LOCUS       DAXLPC010000001       118955 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.001, whole genome shotgun sequence.
ACCESSION   DAXLPC010000001 DAXLPC010000000
VERSION     DAXLPC010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 118955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 118955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..118955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.001"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(513..2009)
                     /gene="lysS"
                     /locus_tag="ACF3UE_000001"
     CDS             complement(513..2009)
                     /gene="lysS"
                     /locus_tag="ACF3UE_000001"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFD3633464.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2120..3124)
                     /gene="dusB"
                     /locus_tag="ACF3UE_000002"
     CDS             complement(2120..3124)
                     /gene="dusB"
                     /locus_tag="ACF3UE_000002"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFD3633465.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3125..4012)
                     /gene="hslO"
                     /locus_tag="ACF3UE_000003"
     CDS             complement(3125..4012)
                     /gene="hslO"
                     /locus_tag="ACF3UE_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFD3633466.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4229..6340)
                     /gene="ftsH"
                     /locus_tag="ACF3UE_000004"
     CDS             complement(4229..6340)
                     /gene="ftsH"
                     /locus_tag="ACF3UE_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFD3633467.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6430..6975)
                     /gene="hpt"
                     /locus_tag="ACF3UE_000005"
     CDS             complement(6430..6975)
                     /gene="hpt"
                     /locus_tag="ACF3UE_000005"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFD3633468.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6975..8420)
                     /gene="tilS"
                     /locus_tag="ACF3UE_000006"
     CDS             complement(6975..8420)
                     /gene="tilS"
                     /locus_tag="ACF3UE_000006"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFD3633469.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8540..9010)
                     /locus_tag="ACF3UE_000007"
     CDS             complement(8540..9010)
                     /locus_tag="ACF3UE_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFD3633470.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9056..9481)
                     /locus_tag="ACF3UE_000008"
     CDS             complement(9056..9481)
                     /locus_tag="ACF3UE_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFD3633471.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9548..9817)
                     /locus_tag="ACF3UE_000009"
     CDS             complement(9548..9817)
                     /locus_tag="ACF3UE_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFD3633472.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9828..11423)
                     /locus_tag="ACF3UE_000010"
     CDS             complement(9828..11423)
                     /locus_tag="ACF3UE_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFD3633473.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11438..14959)
                     /gene="mfd"
                     /locus_tag="ACF3UE_000011"
     CDS             complement(11438..14959)
                     /gene="mfd"
                     /locus_tag="ACF3UE_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFD3633474.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVSDQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14976..15536)
                     /gene="pth"
                     /locus_tag="ACF3UE_000012"
     CDS             complement(14976..15536)
                     /gene="pth"
                     /locus_tag="ACF3UE_000012"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFD3633475.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15889..16863
                     /locus_tag="ACF3UE_000013"
     CDS             15889..16863
                     /locus_tag="ACF3UE_000013"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFD3633476.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17033..18433
                     /locus_tag="ACF3UE_000014"
     CDS             17033..18433
                     /locus_tag="ACF3UE_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFD3633477.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18511..19233)
                     /locus_tag="ACF3UE_000015"
     CDS             complement(18511..19233)
                     /locus_tag="ACF3UE_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3633478.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19312..19818)
                     /locus_tag="ACF3UE_000016"
     CDS             complement(19312..19818)
                     /locus_tag="ACF3UE_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFD3633479.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19941..21740
                     /locus_tag="ACF3UE_000017"
     CDS             19941..21740
                     /locus_tag="ACF3UE_000017"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFD3633480.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21808..23382)
                     /locus_tag="ACF3UE_000018"
     CDS             complement(21808..23382)
                     /locus_tag="ACF3UE_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFD3633481.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23637..24146)
                     /gene="mreD"
                     /locus_tag="ACF3UE_000019"
     CDS             complement(23637..24146)
                     /gene="mreD"
                     /locus_tag="ACF3UE_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFD3633482.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24150..25004)
                     /gene="mreC"
                     /locus_tag="ACF3UE_000020"
     CDS             complement(24150..25004)
                     /gene="mreC"
                     /locus_tag="ACF3UE_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFD3633483.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25159..25797)
                     /locus_tag="ACF3UE_000021"
     CDS             complement(25159..25797)
                     /locus_tag="ACF3UE_000021"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFD3633484.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25798..26448)
                     /gene="rpe"
                     /locus_tag="ACF3UE_000022"
     CDS             complement(25798..26448)
                     /gene="rpe"
                     /locus_tag="ACF3UE_000022"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFD3633485.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26461..27360)
                     /gene="rsgA"
                     /locus_tag="ACF3UE_000023"
     CDS             complement(26461..27360)
                     /gene="rsgA"
                     /locus_tag="ACF3UE_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFD3633486.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27525..29594)
                     /gene="pknB"
                     /locus_tag="ACF3UE_000024"
     CDS             complement(27525..29594)
                     /gene="pknB"
                     /locus_tag="ACF3UE_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFD3633487.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29591..30331)
                     /locus_tag="ACF3UE_000025"
     CDS             complement(29591..30331)
                     /locus_tag="ACF3UE_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFD3633488.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30344..31702)
                     /gene="rsmB"
                     /locus_tag="ACF3UE_000026"
     CDS             complement(30344..31702)
                     /gene="rsmB"
                     /locus_tag="ACF3UE_000026"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFD3633489.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31702..32640)
                     /gene="fmt"
                     /locus_tag="ACF3UE_000027"
     CDS             complement(31702..32640)
                     /gene="fmt"
                     /locus_tag="ACF3UE_000027"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFD3633490.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32633..33124)
                     /gene="def"
                     /locus_tag="ACF3UE_000028"
     CDS             complement(32633..33124)
                     /gene="def"
                     /locus_tag="ACF3UE_000028"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFD3633491.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(33139..35547)
                     /gene="priA"
                     /locus_tag="ACF3UE_000029"
     CDS             complement(33139..35547)
                     /gene="priA"
                     /locus_tag="ACF3UE_000029"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFD3633492.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35800..36105)
                     /gene="rpoZ"
                     /locus_tag="ACF3UE_000030"
     CDS             complement(35800..36105)
                     /gene="rpoZ"
                     /locus_tag="ACF3UE_000030"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFD3633493.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(36110..36724)
                     /gene="gmk"
                     /locus_tag="ACF3UE_000031"
     CDS             complement(36110..36724)
                     /gene="gmk"
                     /locus_tag="ACF3UE_000031"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFD3633494.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(37211..37495)
                     /locus_tag="ACF3UE_000032"
     CDS             complement(37211..37495)
                     /locus_tag="ACF3UE_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633495.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37513..38403)
                     /locus_tag="ACF3UE_000033"
     CDS             complement(37513..38403)
                     /locus_tag="ACF3UE_000033"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFD3633496.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38423..38641)
                     /locus_tag="ACF3UE_000034"
     CDS             complement(38423..38641)
                     /locus_tag="ACF3UE_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFD3633497.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38611..40311)
                     /locus_tag="ACF3UE_000035"
     CDS             complement(38611..40311)
                     /locus_tag="ACF3UE_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFD3633498.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40578..41351
                     /locus_tag="ACF3UE_000036"
     CDS             40578..41351
                     /locus_tag="ACF3UE_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633499.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41432..42001)
                     /gene="thiT"
                     /locus_tag="ACF3UE_000037"
     CDS             complement(41432..42001)
                     /gene="thiT"
                     /locus_tag="ACF3UE_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFD3633500.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(42067..42169)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42175..43146)
                     /locus_tag="ACF3UE_000038"
     CDS             complement(42175..43146)
                     /locus_tag="ACF3UE_000038"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFD3633501.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(43240..44613)
                     /gene="glmU"
                     /locus_tag="ACF3UE_000039"
     CDS             complement(43240..44613)
                     /gene="glmU"
                     /locus_tag="ACF3UE_000039"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFD3633502.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(45116..45934)
                     /gene="purR"
                     /locus_tag="ACF3UE_000040"
     CDS             complement(45116..45934)
                     /gene="purR"
                     /locus_tag="ACF3UE_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFD3633503.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(46101..46925)
                     /locus_tag="ACF3UE_000041"
     CDS             complement(46101..46925)
                     /locus_tag="ACF3UE_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFD3633504.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46898..47578)
                     /locus_tag="ACF3UE_000042"
     CDS             complement(46898..47578)
                     /locus_tag="ACF3UE_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFD3633505.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47601..48539)
                     /locus_tag="ACF3UE_000043"
     CDS             complement(47601..48539)
                     /locus_tag="ACF3UE_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFD3633506.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48784..49635)
                     /gene="ispE"
                     /locus_tag="ACF3UE_000044"
     CDS             complement(48784..49635)
                     /gene="ispE"
                     /locus_tag="ACF3UE_000044"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFD3633507.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(49789..52362)
                     /gene="mprF"
                     /locus_tag="ACF3UE_000045"
     CDS             complement(49789..52362)
                     /gene="mprF"
                     /locus_tag="ACF3UE_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFD3633508.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52503..53309
                     /gene="proC"
                     /locus_tag="ACF3UE_000046"
     CDS             52503..53309
                     /gene="proC"
                     /locus_tag="ACF3UE_000046"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFD3633509.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53388..54944)
                     /gene="rny"
                     /locus_tag="ACF3UE_000047"
     CDS             complement(53388..54944)
                     /gene="rny"
                     /locus_tag="ACF3UE_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFD3633510.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55355..56404)
                     /gene="recA"
                     /locus_tag="ACF3UE_000048"
     CDS             complement(55355..56404)
                     /gene="recA"
                     /locus_tag="ACF3UE_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFD3633511.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56513..57754)
                     /locus_tag="ACF3UE_000049"
     CDS             complement(56513..57754)
                     /locus_tag="ACF3UE_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFD3633512.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(57994..58572)
                     /gene="pgsA"
                     /locus_tag="ACF3UE_000050"
     CDS             complement(57994..58572)
                     /gene="pgsA"
                     /locus_tag="ACF3UE_000050"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFD3633513.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58781..59704)
                     /locus_tag="ACF3UE_000051"
     CDS             complement(58781..59704)
                     /locus_tag="ACF3UE_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFD3633514.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(60443..61729)
                     /locus_tag="ACF3UE_000052"
     CDS             complement(60443..61729)
                     /locus_tag="ACF3UE_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFD3633515.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61722..62990)
                     /locus_tag="ACF3UE_000053"
     CDS             complement(61722..62990)
                     /locus_tag="ACF3UE_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFD3633516.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            63242..63703
                     /gene="mscL"
                     /locus_tag="ACF3UE_000054"
     CDS             63242..63703
                     /gene="mscL"
                     /locus_tag="ACF3UE_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFD3633517.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63762..64208)
                     /locus_tag="ACF3UE_000055"
     CDS             complement(63762..64208)
                     /locus_tag="ACF3UE_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3633518.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64301..64546)
                     /locus_tag="ACF3UE_000056"
     CDS             complement(64301..64546)
                     /locus_tag="ACF3UE_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFD3633519.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64661..65239)
                     /locus_tag="ACF3UE_000057"
     CDS             complement(64661..65239)
                     /locus_tag="ACF3UE_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFD3633520.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65316..65846)
                     /locus_tag="ACF3UE_000058"
     CDS             complement(65316..65846)
                     /locus_tag="ACF3UE_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFD3633521.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65850..66710)
                     /gene="rlmB"
                     /locus_tag="ACF3UE_000059"
     CDS             complement(65850..66710)
                     /gene="rlmB"
                     /locus_tag="ACF3UE_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFD3633522.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66703..67098)
                     /locus_tag="ACF3UE_000060"
     CDS             complement(66703..67098)
                     /locus_tag="ACF3UE_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFD3633523.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(67095..68507)
                     /gene="cysS"
                     /locus_tag="ACF3UE_000061"
     CDS             complement(67095..68507)
                     /gene="cysS"
                     /locus_tag="ACF3UE_000061"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFD3633524.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68504..69040)
                     /gene="epsC"
                     /locus_tag="ACF3UE_000062"
     CDS             complement(68504..69040)
                     /gene="epsC"
                     /locus_tag="ACF3UE_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFD3633525.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(69126..69365)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(69362..70822)
                     /gene="gltX"
                     /locus_tag="ACF3UE_000063"
     CDS             complement(69362..70822)
                     /gene="gltX"
                     /locus_tag="ACF3UE_000063"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFD3633526.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(70992..72149)
                     /locus_tag="ACF3UE_000064"
     CDS             complement(70992..72149)
                     /locus_tag="ACF3UE_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFD3633527.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(72183..73553)
                     /gene="radA"
                     /locus_tag="ACF3UE_000065"
     CDS             complement(72183..73553)
                     /gene="radA"
                     /locus_tag="ACF3UE_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFD3633528.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73616..74143)
                     /locus_tag="ACF3UE_000066"
     CDS             complement(73616..74143)
                     /locus_tag="ACF3UE_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFD3633529.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            74373..75179
                     /gene="proB"
                     /locus_tag="ACF3UE_000067"
     CDS             74373..75179
                     /gene="proB"
                     /locus_tag="ACF3UE_000067"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFD3633530.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            75176..76423
                     /locus_tag="ACF3UE_000068"
     CDS             75176..76423
                     /locus_tag="ACF3UE_000068"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFD3633531.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            76499..76843
                     /locus_tag="ACF3UE_000069"
     CDS             76499..76843
                     /locus_tag="ACF3UE_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633532.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(76960..77286)
                     /locus_tag="ACF3UE_000070"
     CDS             complement(76960..77286)
                     /locus_tag="ACF3UE_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633533.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(77901..79103)
                     /locus_tag="ACF3UE_000071"
     CDS             complement(77901..79103)
                     /locus_tag="ACF3UE_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3633534.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            79220..79735
                     /locus_tag="ACF3UE_000072"
     CDS             79220..79735
                     /locus_tag="ACF3UE_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3633535.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(79934..80380)
                     /locus_tag="ACF3UE_000073"
     CDS             complement(79934..80380)
                     /locus_tag="ACF3UE_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFD3633536.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(80427..81905)
                     /gene="msr(C)"
                     /locus_tag="ACF3UE_000074"
     CDS             complement(80427..81905)
                     /gene="msr(C)"
                     /locus_tag="ACF3UE_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFD3633537.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(82259..82888)
                     /locus_tag="ACF3UE_000075"
     CDS             complement(82259..82888)
                     /locus_tag="ACF3UE_000075"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFD3633538.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(82872..83336)
                     /locus_tag="ACF3UE_000076"
     CDS             complement(82872..83336)
                     /locus_tag="ACF3UE_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3633539.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(83823..85091)
                     /locus_tag="ACF3UE_000077"
     CDS             complement(83823..85091)
                     /locus_tag="ACF3UE_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFD3633540.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(85322..86059)
                     /locus_tag="ACF3UE_000078"
     CDS             complement(85322..86059)
                     /locus_tag="ACF3UE_000078"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3633541.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(86126..86695)
                     /locus_tag="ACF3UE_000079"
     CDS             complement(86126..86695)
                     /locus_tag="ACF3UE_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFD3633542.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            86823..87695
                     /locus_tag="ACF3UE_000080"
     CDS             86823..87695
                     /locus_tag="ACF3UE_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3633543.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            88037..88909
                     /locus_tag="ACF3UE_000081"
     CDS             88037..88909
                     /locus_tag="ACF3UE_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFD3633544.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            88906..90864
                     /gene="nagE"
                     /locus_tag="ACF3UE_000082"
     CDS             88906..90864
                     /gene="nagE"
                     /locus_tag="ACF3UE_000082"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFD3633545.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(91196..92047)
                     /locus_tag="ACF3UE_000083"
     CDS             complement(91196..92047)
                     /locus_tag="ACF3UE_000083"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3633546.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            92170..92637
                     /locus_tag="ACF3UE_000084"
     CDS             92170..92637
                     /locus_tag="ACF3UE_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFD3633547.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(92900..93382)
                     /locus_tag="ACF3UE_000085"
     CDS             complement(92900..93382)
                     /locus_tag="ACF3UE_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFD3633548.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(93482..94345)
                     /locus_tag="ACF3UE_000086"
     CDS             complement(93482..94345)
                     /locus_tag="ACF3UE_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFD3633549.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            94943..95818
                     /locus_tag="ACF3UE_000087"
     CDS             94943..95818
                     /locus_tag="ACF3UE_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFD3633550.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(95963..96115)
                     /locus_tag="ACF3UE_000088"
                     /pseudo
     CDS             complement(95963..96115)
                     /locus_tag="ACF3UE_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(96383..97714)
                     /locus_tag="ACF3UE_000089"
     CDS             complement(96383..97714)
                     /locus_tag="ACF3UE_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD3633551.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(97863..98576)
                     /locus_tag="ACF3UE_000090"
     CDS             complement(97863..98576)
                     /locus_tag="ACF3UE_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3633552.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            98751..100175
                     /locus_tag="ACF3UE_000091"
     CDS             98751..100175
                     /locus_tag="ACF3UE_000091"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3633553.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            100474..101181
                     /locus_tag="ACF3UE_000092"
     CDS             100474..101181
                     /locus_tag="ACF3UE_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFD3633554.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            101168..101491
                     /locus_tag="ACF3UE_000093"
     CDS             101168..101491
                     /locus_tag="ACF3UE_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFD3633555.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(101580..102617)
                     /locus_tag="ACF3UE_000094"
     CDS             complement(101580..102617)
                     /locus_tag="ACF3UE_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFD3633556.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(102938..103921)
                     /locus_tag="ACF3UE_000095"
     CDS             complement(102938..103921)
                     /locus_tag="ACF3UE_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFD3633557.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(104336..105106)
                     /locus_tag="ACF3UE_000096"
     CDS             complement(104336..105106)
                     /locus_tag="ACF3UE_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3633558.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(105099..106034)
                     /locus_tag="ACF3UE_000097"
     CDS             complement(105099..106034)
                     /locus_tag="ACF3UE_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3633559.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(106350..107999)
                     /locus_tag="ACF3UE_000098"
     CDS             complement(106350..107999)
                     /locus_tag="ACF3UE_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFD3633560.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(108116..110719)
                     /locus_tag="ACF3UE_000099"
     CDS             complement(108116..110719)
                     /locus_tag="ACF3UE_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFD3633561.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(110731..111780)
                     /locus_tag="ACF3UE_000100"
     CDS             complement(110731..111780)
                     /locus_tag="ACF3UE_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFD3633562.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(111806..112120)
                     /locus_tag="ACF3UE_000101"
     CDS             complement(111806..112120)
                     /locus_tag="ACF3UE_000101"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_function: GO:0090582 -
                     protein-phosphocysteine-D-fructose-phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HFD3633563.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(112136..112582)
                     /locus_tag="ACF3UE_000102"
     CDS             complement(112136..112582)
                     /locus_tag="ACF3UE_000102"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFD3633564.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(112583..114505)
                     /locus_tag="ACF3UE_000103"
     CDS             complement(112583..114505)
                     /locus_tag="ACF3UE_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3633565.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(114717..115613)
                     /locus_tag="ACF3UE_000104"
     CDS             complement(114717..115613)
                     /locus_tag="ACF3UE_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3633566.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(115606..116286)
                     /locus_tag="ACF3UE_000105"
     CDS             complement(115606..116286)
                     /locus_tag="ACF3UE_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3633567.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(116287..117069)
                     /locus_tag="ACF3UE_000106"
     CDS             complement(116287..117069)
                     /locus_tag="ACF3UE_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFD3633568.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(117062..117979)
                     /locus_tag="ACF3UE_000107"
     CDS             complement(117062..117979)
                     /locus_tag="ACF3UE_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD3633569.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(118143..118397)
                     /locus_tag="ACF3UE_000108"
     CDS             complement(118143..118397)
                     /locus_tag="ACF3UE_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633570.1"
                     /translation="MSTITTITMVASPLGLALFGALFDWKTTQPRLRDSLIFLGGSLA
                     IVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEKKESGN"
BASE COUNT        33814 a        25297 c        20978 g        38866 t
ORIGIN      
        1 tttttggctg ccgtagcaac ttttatatca tatcagagag acaagcgatt gtcaactctt
       61 ttttaaaagt ttttttcgat ttcgtttttc gaaatctttc ggcaactcat ttaccataac
      121 ttatcgtttg ttatttgtca agaacttttt tgaagttttt ttcgatagaa tcaagcttcg
      181 caagtggttc ttttttaacg actcagttat cttatcatgt cgttagtaac atgtcaataa
      241 cttttttgtt atgtttttga ataaatattt tcttctgtct tttggacaag taataatata
      301 ccaactaaat ttagcttggt caacgaattt tttgtatttt ttcaagtttt tttcaataaa
      361 cgattattca taacttttct ttctttatcg ttcgttttcg tcttctttaa tgtctagaat
      421 agtcggcatt agcttttgaa ctttcgttat tatttattcc tttctacaca gcaaaagctg
      481 cctaaggaat tccttagaca gcttttattc gattatctca ttgttgggaa tagcaaaaca
      541 tcccgaattg attgtgcatc agttagcaac attactaatc tgtcgatccc gatgcctaga
      601 ccaccagttg gcggcatacc gtattctaag gcttccaaga agtcttcgtc tacaccgtga
      661 gcttcgtcat ttcctagttc acgttctttt tcttgcgctt cgaatctttc tctttgatca
      721 attggatcgt tcagttctgt aaaggcatta gcaaattcgc gccccactat gaatagttcg
      781 aatcgatctg tgaatcgagg atcttctgga tttttcttcg ctaaaggcga aacttcgact
      841 ggatgtccgt atacaaacgt cggttgtgtc aatgtttctt caacaaatgt ttcaaagaat
      901 tcattgataa catgtccgac acccatagct tcggttactt ctacattgtg tttttcggct
      961 aaagctaatg cttcttccaa tgtcatttct tgccagaagt ctacaccagt ttgttctttg
     1021 attgcatcta ccatatggat gcgtttaaag tcactttcta agtcgacagc ttgtccatca
     1081 tatgtgattt ttgctgttcc tagtactttt tcagctgcgt tacggataat accttctgtc
     1141 agattcatta catcattgaa atcagtatat gctgtgtatg cttctaacat cgtaaattct
     1201 ggattatgtg tagtatcaat tccttcatta cggaaaacgc ggccgatttc ataaactttt
     1261 tccattccgc caacaattag tcgttttaaa tgaagttcta gcgcaatacg caaatataaa
     1321 tcaatgtcca gtgcattatg atgcgtgata aatgggcgtg cggcagctcc acctgcctca
     1381 ttgtgcaata ctggtgtttc tacttcaata tagccattgc catctaaata gcgacggatt
     1441 tcgctgataa tttggcttcg tttcataaat cggtcaaagc tttcgcgatt actgattaaa
     1501 tccaagtagc gttgtctgta gcgttgttca atattcgtta agccatggta tttatctggc
     1561 agtggacgaa gtgcttttga caaaatcgtg atttctgaag ctttgataga aacttcgcct
     1621 gtgtctgttt tcatgatttg tccagttaca ccaaagaaat ctccaaggtc tgcatgtttg
     1681 aatacttcat aggcctcatc acctacttgg tcttttctta cataaatttg aatttggcct
     1741 tcacgatctt gtagatgcgc aaatccagct ttcccttttc ctcggcgagt catcatacga
     1801 ccagctacac tagcggtcaa tcccatttct gctagttctt cttttgttct tggatcaaat
     1861 agttcatgca attcttctga gttgtgcgtg cgttcaaatc gttttccaaa tggatcgatt
     1921 ccatcttcac gcaattgttc cattttttga cgacgtacaa gcatttgatc atttaaatct
     1981 tctacttgat gttgttgttc ctgtgtcaca aaagttcctc cattctcatg ttaatctctt
     2041 tcctataatg ccaatgaaac acaaaaaaag caagccgaac ttggaatttc ggcttgaaaa
     2101 ttcacgaaaa acttagaaat cacaacgttt gtttcaatag tactttttcc gctttttcta
     2161 caaattgatc cagcaggtca ttgatttctt gctgtttttc tgtctgattg attgctactt
     2221 tcactttcgc tgctcgagga atccctttta aataataagc cgcatgtgtt ctgaattctc
     2281 tacaagctac tttttctcct ttgagatctg ctaagcgttg taaatgaagt ttagctgtag
     2341 caattttttc ggctggtgtt ggttcaggaa tcagttcccc tgtttcgaga taatgctgtg
     2401 tgcggtgaat catccatgga ttgcccagcg ctgcacgacc aatcatcaca ccgtctgcac
     2461 cgacatagtc aagcatccat tttgcatctt ctggcgtttt gacatccccg ttccccataa
     2521 atggaatcgt caaatgtttt ttcacttctt tcaatacttc ccagtccgct tttccttcat
     2581 acatctgaac ccgtgtacgt ccatgcatag cgatggcact tgctccagct gattgtgctg
     2641 ctaatgcatt ttctacagca aagacgtgct cttcatccca accaatacgc atcttgattg
     2701 ttactgggat atttactgct gaagaaacag cttggaccat ttcgtatact ttctcaggat
     2761 ctaaaagcca ttttgctcct gcttctgctt tgattacttt atttactgga cagcccatat
     2821 tgatatctat tatatcggca gctgtgtttt cttcgacaaa ttgagcagct tcaactagac
     2881 tatctttatt tccgccaaat atctgtaaac ttaatggatg ttctgtttct tcaatgtgga
     2941 gcatctctaa agtttttttg tttctgaaat gaataccttg gtcactgatc atttcacata
     3001 cgactaagcc cgcaccaaat tctttgacag tgactcgaaa tgctgaattt gttattccag
     3061 ccatcggtgc aacaacgaca cgattaggga tttccacatt gccaattttc catgtgtgtt
     3121 ccacttaaat ccctcctaag gcttctttct tcaatccatc taattcttct tcgctatact
     3181 tgtatttgtt attacagaaa gaacaaaccg cttctgcacc gtgatcttcg tctatcattg
     3241 cttggatttc ttctgcacct aacgcgataa ttgcttctgc aaatttttct tttgaacagt
     3301 cacatttgaa ttgaacaggc attttttcca aaatgttcaa ttcttctgta ccaagcaatc
     3361 ctttcaatat ttcttctggt gtctgtcctt catctaagag ggtagagatt cttggtgtcg
     3421 tttttaattg ttcttcgatc ttgctgattg tttcttcatc ggcacctggc atgatttgga
     3481 tcatgaatcc tcccgccgtc ttgatgctgt cgtcagtatt gaccaataca ctcagtccaa
     3541 cagctgaagg gatttgttct gagatagcaa gatagtaagt aaaatcttca gcgatttctc
     3601 cagaaacaat cggcgtttgc ccagaaaaag gttcttttaa tcctaagtct tttgtgacag
     3661 taaacattcc ttgtgttcca actgctcccc gcacatcgat tttaccttca ctatttagag
     3721 gaagactgag atgcggattt ttgatgtaac ctttcacatc tccctttcca tttgcatcta
     3781 ctacaattcc tgttgctgga ccatcgcctt ggattcgaac agttagtttg tcttctcctt
     3841 tgagcgtcgc accaagtagc agactaccga ccaatgtccg tcccaaagca gctgaggagg
     3901 tgtgccaagt atcatgacgt ctttgtgcct ccgctacggt atttgttgct tgaacggcgt
     3961 atgctcggac gaatccgtcg tgagcaagtg ccttaaccaa ataatctttc atttgttatg
     4021 tactcctttt tccgttttta aactcatagt gaatcatact agcaactact gcttttttca
     4081 actttggaat gcttctttta aaaataattc agaatcatct agaaaacagg acatcaccct
     4141 atttacaact taaataaaga aatctcccga aaaccggttt ttgttccggt tttcgggagt
     4201 catatcagat caattgacct atattttttt atttgtattg atcgtctgaa tgattatctt
     4261 ctgattgttg agaatctgaa tcatgttctg ctttattttc ctcattcagt tcatgttttg
     4321 cttcttcaaa atcacgtttt tcttccgctt gtttttcagc gtctttttct tccaaagcac
     4381 gttttgcttc ttcaaaagtt ttcgcttctt tttcgcttgg ataatcattt gactcagtac
     4441 cttcaggcat cacaccgtgt tcaaacaatg acttgattgc tttggcatcc aatgtttcga
     4501 attccaaaag tttttcagca atcagtttat gctgtgcacg atgagcttcg atgatttctc
     4561 gagctttatc atgagcttcc atcaagattt ttcgtacttc ttgatcaatc tcgaaagcga
     4621 cttgttccga gtaagctttt gtttgaccat agtcgcggcc aacaaacact tgatggtttc
     4681 cttcatattg aacaggacct aaacgatcac tcattccata ttctgttacc atgcttcgtg
     4741 ctagagctgt cgcttgctca aagtcattgg aagcaccagt tgattggaca ttgaagatga
     4801 tttcttcagc tgtacgtcca ccaagtaagc ctacgatttg ttcaaacata tcttctttcg
     4861 tcatcaagaa ctgatcttct tttggtaaag cgatcatata tccgccggcg cgtccgcgag
     4921 ggatgatcgt tactttgtgg acgacccgag cgcgactcaa tactaatccg acaatcgtat
     4981 gaccagcttc gtgataagca accatttcgc gttctttttt gctgattacg cgatcttttt
     5041 tagctggacc tgcaatcacg cgatcttccg cttcatcgat atcagaagca tcgattttct
     5101 ttttatttct tctagcagct actaacgctg cttcattcaa gacattttct aaatctgctc
     5161 cggcaaaacc tggtgtctgt tgagccacaa ctttcaagtc aacgtcatct gccatcggtt
     5221 tattccgtgc atggactcgc aagattgctt cacgaccttt tacatctgga cgtccaacta
     5281 aaatctggcg gtcaaaacgg cctggacgta gtaacgctgg gtctagtaca tcagaacggt
     5341 tggttgcagc aatgacgatt actccttcat ttccgtcgaa gccatccatt tctacaagca
     5401 attggttcaa tgtttgttcg cgttcatcat gtccgccgcc cataccggca ccacgttgac
     5461 gacctaccgc atcaatttca tcaatgaaaa tgatagctgg tgcgtttttc ttcgctgttt
     5521 caaacaaatc acgaacacga cttgctccaa caccgacaaa catttctacg aaatcagaac
     5581 ccgagatcga gtaaaacggt actccagctt ctccggcaac agcttttgct aataaggttt
     5641 tacctgttcc tggaggtcct tctaaaagta cacctgccgg gatacgggca cctaattcaa
     5701 caaatcggcg aggatctttc agaaattcaa caacttcaac tagttcttgt ttttcttctt
     5761 ccgcacccgc tacatcagaa aaacgtacgc gattagcttt tttgtctgct tctttggctt
     5821 ttgatttacc aaagttcatg acacggccgc caccgccacc gccgccgcct tgttgtccca
     5881 tcatcatgta aaagaaaaag atgatgatta cgattggcaa gaagctaagc aatagggaaa
     5941 cccatatacc gctgcttgat tcttctttta ctgttgtagc aactttgttt tcttttgcca
     6001 gttctgttac ttggctcaat gttgtatcat ttggcaaaat gattgttgtg aaatgggtag
     6061 tagtcgtatc tgttgaacct aagatagcta acccaccgct gttagcgacg gtctgctgtt
     6121 ctttgtattc accagtgatc ttatatacac catttgcagg ctgcacttca aattctttga
     6181 tcttgcctgc ttgtagttgt tctgtgaatt ttgagtactc gatatctgac gatcgctggc
     6241 cgttattacc aaaaatgaaa taaacgacca ttaccatcgc taagattacg aggacataat
     6301 acaaggcatt tttcatcatg ccgttgttct ttttgttcat agttgccctc cctaagcgtc
     6361 aatttaattt aacagttttt tatcaatcct gaccattcta ttgtaccata atttaattga
     6421 gatacagcat taatttgatt gataaacact aggtttcaat acaccgatgt acggaaggtt
     6481 acgatatgct tctgcataat ccaagccata accgaccaca aattcatttg gtacgttgaa
     6541 gccaacataa tctgcttcga tatttactac tcttccttca ggtttgtcaa gtagtgtaac
     6601 aattttgact gattttgctt tgcggtattt gaaaagatcc actaaataag caagtgttct
     6661 tccgctgtca atgatatctt caacgatcaa cagatcgcga ccttctacat tcgtatctaa
     6721 gtctttgacg atttttactt cccctgacga gactgttgca ttcccgtagc ttgaaacatc
     6781 catgaaatcc aattccaaat acgtatcgat agaacgaacg atatctgcca tgaatggtac
     6841 cgctcctttt aagacaccta ctactagggg attggtgttt tggtaaattt ctgttaactc
     6901 tttgcctagt tctttgcaac gaacttgtat ctcttcttgt gagatcaaaa ttctctcaat
     6961 atccttttcc aacatcaggt tctccttcca attgcttctt tttgatattt gtaaagaagt
     7021 atgtagtgta ttttatcagt ttcttcacga atactcaaat atgaaaaggc aaaaggtatc
     7081 aagctatata tatttctttt ggcatctgta atgatccaag catgctgcct ttgtgaatta
     7141 ggtactttct gatcgataaa atatctagat actttttttg tgagattctc tgttaattta
     7201 atgcggtctc ctgcttttct tttttcgaca tacagttgca catcagcagg aatccaaatg
     7261 tcatgagaaa atagagacca tgaatctgtt gctttgatgt cccctgcatt ttcaggtttg
     7321 accagaccaa tccattctgt ttcattcaaa tatattcctt gttctggaat cagcaacaag
     7381 cgctggtctt ctgtctggct agttgcttgt ttttcttttt tagagagtac aacaaaatga
     7441 tactctcttt tcagtatcca attattgcca atactgagtt gccattggct ttttttctgt
     7501 tgccactggt ctaaaatcga ctccatttgt tgttctttca aaataattcc tgtttttgag
     7561 aatgctttgt cgaaaaagga gtaaaaaaaa tagtatcgtt cagcatctgt catttcttca
     7621 atcatttctg cagaaaatcg aaattgttcc tcccactgtt cgacttcctt ttcgatcaac
     7681 tgtcccatat atttttgaat gacttggtct gcccattgga tctgttgcga aaattgctgg
     7741 aaatgtctca acgcctgtgt attttcttgt ttcaattgag gaactaccaa atgacgaagc
     7801 cgatttctct ggatatctaa caattggttt gtctgatcct caaagtaaac aagctgcgat
     7861 tccgctgcat aagtatatag gtcttctttg ctaaaactca gcaacggacg aatcagtctg
     7921 cccgtagcaa atggttgtac ttctttgatt ccagaaaaag tatttaactg tcccccacga
     7981 acgattttca ttaacaccgt ctcgatttga tcatctccgt gatgagcagt catcaacgtg
     8041 tcatattgtc cttcttccat cacgcgagtg aattcttgat aacgaaagtt acgagcttct
     8101 gtttctatgg cggatttggc tggatcttcc caaatactta catataaagg gagattcttc
     8161 tcttcacaat atgagcgaag ataggcagct tcttctgctg attcttctct taattggtga
     8221 ttgatgtgga cgatacctaa agaaaaaccg atttggcgtt gcacttgtaa aagtaaatgg
     8281 agcaaaacca tcgaatcaac accacctgat accgctgcta aaattctcga tccttgttgc
     8341 cagaatcctt gttcattccc gtgccgaata aatgactgct gtaatagcgg tgcttttttc
     8401 ccgccttttt caacgttcat cctttccaca ccctttcttc ctaaaaaaaa gagagcggga
     8461 aaacgtctaa aacgacaatt aacctgccct ctgttgatac tatgacccaa atagtcgcac
     8521 tatcattatt tgcggctttt tagctgcgac gtccgccacg gccaccgcgc tttccttctg
     8581 tgtttcgctt caatgaagat aagcggtcat cgctatcttt caaaaatgaa ctcatcaatg
     8641 aatcgaagtc ttctttttga gctgaaggtt gactgcgaga aaaagatttt ttctgtgctg
     8701 gacgatttcg gttgtcacgg ggatcttttt gttgatattt tttaggacgg ctttcttctc
     8761 cagattcagc aggttgttcc tgcgctttcc ggatagatag tccgattttt ccatcatcat
     8821 ttactgaaat aactttaact gttacttcat ctcctacact taaaacatca tggatgtctt
     8881 ttacatagcc atttgacact tcgctaatat gaactagacc cgtttttcca gcacctagat
     8941 caataaacgc accaaaattt gtgattcctg atacttttcc ttgcagtttt gctcctacct
     9001 cgattgacat aaaaaaaatg ttcctcctaa ttatttccct tttttatatt cctgcttatt
     9061 ttgcagttgt agaactagtt gattgatctg tttcatttgt cgagctgtct gtatttgatt
     9121 ctaatatagg ataaactttt tcaccgtctt ttgagtaaaa gaatttgctt ctggcaagtt
     9181 tagctacata ctcatcatct ttcagcaatg aaacatcttg gtgcagctga tcaacgtctg
     9241 cgttgacttc tttcatttca gtatttgctt cgactctcaa ttcgttcaat tgatgcatcc
     9301 tttgcatgtc atggaaaatc tgcacaccta ttatcgcgaa aatgaccaaa gcaccaacaa
     9361 aaattgcagc cagtctgcgt cttcgaaaaa tcagttgacg ttgttgttgc tgaaattcag
     9421 catacttttt ctttgcatat tccgtatcta gcgcagcgat tttattgctt tttttcgtca
     9481 cttggattcg ctccaatctt tttgattgtc tttttcatta taccaatatc gtgaaagctt
     9541 gtctaatcta tttctctagt gtttctgtgc gattttcaga aataatttcg tacatttttt
     9601 gtgcatcttc ttttttggtt gattcatgta attccgtaat tttcacttcc aacgttttgt
     9661 tgccaaactg gactttcaaa atatcgccta ctttgacatc actggaagat ttcgccaatt
     9721 taccgttgat ttgaattctt cctttatcag ctacttcttt tgctactgat cgtcttttga
     9781 tgattcggga aatttttaaa aatttatcta atcgcatatc ttattcctca ctttttaatt
     9841 tttttattta atcgcaggat tttcttacca aaaggcaaca ttagccattc tcgtactgta
     9901 aacagacgaa gacgaatcac tgcataaatg aacacagaag ccccgatccc aactcctatc
     9961 acgctgacaa aaaaagcagt ggaacgatga gttacaggac caaatactat attcaataca
    10021 ccataataca gcagcagtac tactgtcata caaagaaggc tgaacatcaa cttccgtcca
    10081 aaatgccgtt ctttccaaaa agcatttagc tcttttgttt caattcgaac aaaataccaa
    10141 agcgtcacac ctaatcctaa aagggtagac aggcttgcac ctgctgttcc taataaaccg
    10201 gtcagaaaag aagtagtcaa tccttttacc aatagtcccc atcctgcgcc ttttaaagaa
    10261 gggcgaaacg agttcttgct ttgagcaata ctttgataag cttggatgac tgcagtgaaa
    10321 gcaatggaaa aaacaaataa tacaagcgct gcatttcccg cataatcttt aaacaacgca
    10381 taattgatat aagggagcag caaggctaat cccaaagacg cagctaatgc taaagcggtc
    10441 gtcaatctaa gatagatttt ggctgtctgt aaaaactgac gatagatccg gttggtcaaa
    10501 tgacgagtca acgcaggcag gaatgtcgca cttaatgcag tggcaatcac taaacctaat
    10561 tgtactaaag gctgacctcg atcatagacc ccttttgcta tcttcgcacc gtattctgac
    10621 agtccgtaaa cttccaaagc attttttaca aagaaagagt cgatcagctg gaaaaagata
    10681 agcaatccac tataaatcga aaccagtccg ccttctacca gaaaacgccg gatcaagggc
    10741 tttgacggct gtttgaacaa tggaaaccgt cggaagctta acgctcctcc atgaatcttt
    10801 tgttcatagt agtgaaggat cccatatgcg cataaaccgc caaaaacagc tccactcatt
    10861 gctgccgtcc ctgtttggta caccgtccat ccaagctttc taaaagcaaa cgcactacag
    10921 acaatcacaa aaacacgaac gaactgctca actacttgag aaacagcagt tggttccatc
    10981 aagaatcttc cttggaaatt ccctcgataa aaagatagac caggcatcag caaaaaggta
    11041 aaggaaacta cttggatcag cggtttcaat tgtatgtctc ccatcatcca agcaatccag
    11101 ctgctaaatg caaagacaaa caaccacaaa aagacacctg tccaaaatac taagggataa
    11161 agattttgca aagcttgctt tcgctcgaaa ggattctttc tttctgcaac gtactttgat
    11221 atgaactgcg gaagaccgga taaagctaaa gtcattgcta tcccataaat tggataaact
    11281 tgctgataaa cataaaaacc ttcgtcgccg actaagtttt ggaggggaat tcggtaaagg
    11341 gcacttaata cttttgctat gaaagaagca atcgtcaata caaatgctcc ttgcatgacg
    11401 cgccgcattt ctttatgatc caaatcattg ctccttccta cgctgacaga tatttttgct
    11461 cacgcaacgc tttgacaaac ttttggattt cctgaagcca tactgcttct tccatttggt
    11521 tggggatcgt caagcgtatc accatctgtt ctttttcaac gcctagactg gcttttagtt
    11581 ttgtcgctgt cagtgcttcg aataactgtt ccacactata gcgttttgtt ccaactttac
    11641 ttagagtaaa gactatatgc gcctcctgtt tccttatcgt ttctaggagc gctcgatcgc
    11701 catccatttt gatctgccca attgtcaaga gatgtgctac ttcttctgga tattctccaa
    11761 aacggtcgag cagatcatct tctagttcat ctagcatttc ttgcgaatca agttcacgaa
    11821 ttcgtttata gatctcgatt ttctgccgtt gatctgacac gtatgtttca ggtagatacg
    11881 catcgacacc gaggtcgatc tcaacagtgg tcttctccac ttgactattc tttccttgtt
    11941 tacgagaaac agcttcgctt agcatttgag aatacatatc gaaaccgact gcatcaataa
    12001 atccatgctg ctgagcacct aagagattac ctgcaccgcg aatggaaaga tcccgcatcg
    12061 caatcttgaa tccagatccc agttctgtaa aatctttgat tgcctgaaga cgtttttcac
    12121 tgacttcgtt aaggatcttc tgctgctcat acataaagta agcatatgcg acacggctgc
    12181 ttcttcctac ccgccctcgc aattggtata acgtggataa tcccatataa tcagcgttct
    12241 caacgaacaa cgtatttgcg ttcgggatat ctactcctgt ttcaatgatg gttgtagtga
    12301 caagaacatc atattgacct tcaataaatt caaaaagcgt attttctaat tgcgcctctg
    12361 tcatttgccc atgagcataa ccgatccgtg cttccggaac gagttcttgg atttcttcta
    12421 ctttttgttc gatcgtttct acccgattat ataaatagaa tacttgtcca cctcgtccca
    12481 tttctcgatg gattgcttcg cgaatagccc caggattttt ttccataaca tacgtttgga
    12541 tcggataacg attcgcaggc ggtgtttcga ttactgaaag atcccgcacg cctaacatcg
    12601 acatatgcaa agttctcgga atcggtgttg cagtcagagt caaaacatcc acttgtgcac
    12661 gtaactgttt caatcgttcc ttatgtttta caccaaaacg ttgttcttcg tcaatgatca
    12721 gtagacccaa atcgctaaat tcaatatctt ttgacaaaat tcggtgggtt cctacaacaa
    12781 tatcaacttg acctgtacgc agttgttcga tggtttcttt ttgttgcttt cttgttctga
    12841 aacgacttaa tagcccgata tttacgggga aaccttcaaa tctttccagc atcgtttcat
    12901 agtgctgctg tgccaagatc gttgttggaa ctaaaaaggc tacttgtttg ctttccttta
    12961 tcgctttaaa ggccgctcga agcgctactt ctgttttccc ataaccaaca tcacctacga
    13021 gtagtcgatc cattggtttt tctttttcca tatcccgttt gatctccgct gcacttctca
    13081 actggtcatc agtttcagag taggggaagg cattttcgaa ttctttttgg taggcgtcat
    13141 caggtccaaa agcatatcct ttttctgact ctcttgcggc atataatttg attagatcgt
    13201 cagcgatatc ctcgattttt gaagagactt ttcgcttggt tttcgtccat tcacttccgc
    13261 ctagcttatt gatgcgaggc gctttggctt cagaggcgac atatttttgg atcagattca
    13321 gttgagtaac aggaataaac agtttgtcgt cgttttgata caaaatagtc atatagtctt
    13381 ggtgaacgcc atctacttct agcgtttcca tcccaatgta tttcccgata ccatgattgg
    13441 catggacaac gtaatctcct gcttttaact cattatagct tttcaatcgc tctgcgtttg
    13501 ttactgtttg acgtctcgtt tgttttttcg tcgttttttg gaaaatttct ttttctgtga
    13561 tagctactat tttttcttga ggaagttcaa aaccagcctg caaagctcct tcaactaatt
    13621 gtacctgtcc tctgatcaat gcattttttt ctgtttctac tactaatatg tcttcatctc
    13681 gaagcatttg ttctgctttg cgtattctgt cctttgtcgg aataaagatc acaacagtct
    13741 gtttttgctt gcgccaacgg tccatttctg ttttcagcaa tggcatttgt ccgaagaact
    13801 gttgcatcgt ccgatattga aaattatgga ttgcttggaa acgaagattt cccatccctt
    13861 tttggaagag tgagaaaaag gttgtggtga acttttcctt ctgcacgatt ttttgtatat
    13921 ctgctgaaaa tgtctgctca gaaaacaccc gcaattcgct gattttttga gtctgccatt
    13981 ctgccgcttc cctttcgatt tcccgatttg tttccatgat tcgctgataa tcatcaacga
    14041 ctagtaaact atttgaaggg aaataatcca agatcgtcac agattcttgg taaagaagat
    14101 ctgagtagaa ttttgcttct tctgtcggga cacctgcttg ccagcttgaa gtcagctgac
    14161 cgaagtaatc ttgcaaaaac tcgcggtctg cttcttctgt ggtcgcagca agccgttttt
    14221 ctagcatttt ttgcatttgc tctattccat gttctagatc ctctggtccg tagacttgtt
    14281 cactcgttgg ggaaacccag atttcttccg ttttttcgat tgagcgttgt gtttctgctt
    14341 caaaataccg catagaatct atctctacat caaatagttc tacacgaaca ggataggttg
    14401 tcgttaacgg gtaaatatcg ataatgcttc ctcgaatact gaattctccc ggttttgcga
    14461 ccatctcttc tcgtacatag cccatcaaag tcaattggcg aggaagattt tccacgtcta
    14521 tctcatcacc aatatgccaa ttcaattgcg cctgtagcca agttttctta ttcggcagtc
    14581 gtttgtgcaa agatgcgact ggcaacaaat agatacctgc ttttttttct tgaagtgcgt
    14641 taagcgttgc aactctctcg cctcgcgctt ctggagaaga aaaggccatt tcagcagaaa
    14701 gcacttcatc cactggaaat aaatggatct gatcttgcgg aatcacatgt tgcagatctt
    14761 ctgctaactg attcgcataa tacaaatttg gcatcagaat aatcatgttt ttatttgttt
    14821 tcttaaacgc tcgagcaaat agaagtgttt tcgctgagcc cgctaatcct gtgattagtt
    14881 gtctaggcat tttttcttct aaattgctga cccattcttt tacttgcgga tcttttccga
    14941 ctaattgaat aatatccatt ccttttcctc cttcctcaat tgaatcgatt catcgcatcc
    15001 acgaacgaat gcccttctat gagatattcg actgctttaa cagattgaca catgctttct
    15061 tctatcaaag gctgattttc tttgctgaaa ggactaagca catgctggac tactgttttt
    15121 ttcccttctg gcctgccgat tcccaccttg attcgatcaa agacattcgt attcaaatgg
    15181 gaaataatac ttttgatacc gttatgcccg ccggcacttc ccttttgacg gagccggatt
    15241 tttcccactg ccagatccaa atcatcgtag attacgacta attcctctgg ataaatccca
    15301 aaataagtca ttagtgggcc gactgcacga ccagattcat tcatgaatgt ttgtggtttg
    15361 actaaaagga tcttttctcc attatgaaaa aattcggcaa cttctgcttc gaacggattt
    15421 tttttgaaag tagcttgatg ctcgcgtgca attttatcca cgaccataaa gccgatattg
    15481 tgttttgtat attggtattt ggtacctggg tttcctaacc cgacgatcat tttcattttt
    15541 gttttccacc taattctaaa aagcagcaca aaaggctgga ctgctaatta gcggtccagt
    15601 ccatcgagct tttttctttt ttacacttgt caatgcatag tataacacaa aacaaggcgt
    15661 ttcggctaaa agagaatcgt taataaatga taaagaaatt aaaaatttct tcaaagttta
    15721 atgaaataat tgatatataa aaatagtgaa ataacgcaca tgtaagcttt tacatataat
    15781 acaaccttgt tatctgttat attttatagc caaatagcgt gacatggggc ttgagaaatg
    15841 ttagcataag catgggaaaa aacaaatcaa tggaaggatt gatactaaat gactgcagct
    15901 gcagaaaaaa aagatcatca aaaagttatt cttgttggag acggcgccgt aggttctagc
    15961 tatgcctttg ctctagttac tcaaaatatc gctcaagaag taggtattgt ggatatcaat
    16021 actgctaaaa ctgaaggaga cgcaattgac ttgtctcacg ctttggcatt tacttcacct
    16081 aaaaaaatct attctgctac ttacgcagac gcacatgatg ctgacttagt tgttattaca
    16141 gctggcgcac cacaaaaacc aggtgaaact cgtttagact tagtaaacaa aaacctaaaa
    16201 atcaaccgcg atgttgtcac acaaatcgtt gaatcaggat ttaacggtat ctttttagtt
    16261 gccgctaacc cagtagatat tttgacttac tcaacttgga aattctcagg tttccctaaa
    16321 gaacgcgtaa tcggttcagg tacctctctt gactcagctc gtttccgtca agcacttgcg
    16381 gaattagttg acgttgatgc acgtaacgtc catgcttaca tcttaggtga acacggagat
    16441 tcagaattcc cagtttggtc acatgcaaat gttgccggct tgcaaatcta tgaatgggta
    16501 aaaaacaacc cagaaatcga tgaagaagct atggttaacc tattctttgg cgtacgtgac
    16561 gctgcttaca caattatcga gaaaaaaggc gctactttct atggtatcgc agtagcatta
    16621 gcacgtatca ctcgtgccat cttagatgat gaaaatgctg ttcttccttt atcagtattc
    16681 atgaatggcg aatatggatt gaacgacatc tacattggtg cacctgctgt tatcaaccgt
    16741 caaggtatcc aaaaagtaat cgaaattcct ttaagtgaca gcgagcaaga ccgtatggct
    16801 gcttctgcta agcaattaaa agaaattcta gatgaagctt ttgctaaact agacgctgaa
    16861 taatctttga acatgacgga aaacatctat tcggtgtttt ccgttttttt attttatcac
    16921 ccttatggtt tctaaatttt ttcataaagt agagataacc ttcgtctttt cctctaaatt
    16981 atgctatcat gagaccgttc caccctaaac ttttacttaa ggagttgtcg atatgacaag
    17041 atcttcgcat cgaaaaaaat cgaaacatgt tgctttgctt tcagttcttg gtgttctctt
    17101 agtgctgatc agcttttata cctatcgcag tacatactac acaaagcatt ttttgccgaa
    17161 tacagaaata aatggaataa atgtcagcaa tctaacagtc gaaaaagcaa atgaaaaatt
    17221 aaaagaagct tattctgata aaaaactggc tattaaagaa gatggaaaag tctggcagga
    17281 agtaccaaaa tccgagctcg gctacaaaga tgatttcact tcggagcttt ctccgatcct
    17341 aaatgaacaa aacggatgga cttggggaat gacttatgtc tcagcggcag aaaaacaaga
    17401 aatagatcct gtcagtcaaa accaccaaaa actagacact accgttcaga cattgacaac
    17461 taagctgact gatttgaaca aagaccggac acctactact gatgcaacga tcgaaaaagc
    17521 aggtgactct ttcgttatca agcctgaagt caatggaaat acgatcgacg tcgatgctgc
    17581 ggtcaaacaa ttaaaaagtg cggtaaactc tggtaaagat acaattgaat tgactgaatt
    17641 caaagaaaaa ccaaaagtaa catctgaaga cagctcactg aaagaacaac tcgcatccat
    17701 gaatgctatc gcaaatgtaa aagctactta cagtataaac ggtgagactt tccagatccc
    17761 atcaagtgat attatgagtt ggctgaccta caatgatgga aaagtcgatt tagatacaga
    17821 acaagtacgt caatatgtaa cagatttagg cacaaagtat aacacaagta cgaatgacac
    17881 aaaatttaaa agtacaaaaa gaggagaagt tacggtccca gttggcactt acagttggac
    17941 gatccaaaca gacagtgaga cagaagcatt gaaaaaagcg attctggcag gccaagattt
    18001 tactcgttca cccattgtgc aaggtggcac aaccgctgat catccattga tcgaagatac
    18061 gtatatcgaa gttgatctgg agaaccagca tatgtggtat tacaaagacg gaaaagtggc
    18121 ccttgaaaca gatatcgttt ccggaaagcc aactacacct acacctgctg gagtcttcta
    18181 tgtttggaat aaagaagaag atgcaacttt aaaaggaaca aatgacgatg gaacacctta
    18241 cgagagtccg gtaaactact ggatgccgat tgactggaca ggtgttggta tccacgattc
    18301 agactggcaa cctgaatacg gtggagactt atggaaaacc cgcggttcac acggctgcat
    18361 caacacccca ccaagtgtaa tgaaggaatt attcgggatg gtcgaaaaag gaacgcctgt
    18421 attggtcttc taacaaaaat aatatataaa aagaaagcac ccgtacgatt ggtacaggtg
    18481 ctttcttttt attatctaac aatgtgctac ttacatttca gcagcagtaa agacttctga
    18541 aacatcatca tcgtcttcta gcttatctac tagacgttcc aattgctctt tttgttcctc
    18601 atttaaatca atcgtcgttt gtggaatcat cgtcaattct gcttgcgcca aagtgaactc
    18661 tttttccaac tcatctcgta cagcagcaaa atcttctggt gcagtataaa tctcgaatac
    18721 ttcaggagaa gtttgcagat cttctgcccc cgcctctaat acatcctcaa acatcgtctc
    18781 ttcatcaaca gtcaacccat cgcgttcaat agcgatatat cctttgcggt caaacaagta
    18841 actgactgaa cccgtttctc ccagtgatcc accgtttcga gtaaaagcta ctcggacatt
    18901 tgtcgctgtc cgattacggt tatctgtcaa tgcatggact aagattccta ctccacccgg
    18961 accatatcct tcatacgtga tttcatcgta attcgtttca tctacggcac tcgtagcctt
    19021 tttaatcgcc cgttccacat tgtcgttagg catatttgca gcttttgctt tgtccacaac
    19081 aagccgcaaa gctggattca tagatggatc aggaccgcct gctttagctg ccatataaat
    19141 ttcacgagaa agtttctgaa agactttccc tcgttttgca tcttgggcat tttttcttcc
    19201 ttggatatta tgccatttac tatgtcctga catgattttt cctcccttgt tcttttgaga
    19261 atacacttct attctagtac tatttcacaa aaaaacaaag ccacagccaa tctataaacg
    19321 cttcttgaat gccgcaaaaa gcacacataa tatcacagca gtcagagcac cgatcgaatc
    19381 caacatgaca tcttggaaca taggtgttcg tccaccggtc atcatctgat ggaattcgtc
    19441 caaacctgcg taccctgttg ctgaaagcca agcaaggatc gctgtcagcc accaaatttt
    19501 tagcttgggg aaaacaccta aaaacaagct gcctcccaaa ataaaatagg taccgaaatg
    19561 tgcgcccttc cttaaaaaga actctaaaaa tttggcgtag cccagatggt tgatactcac
    19621 catacttcca ccataattaa aacgtatacc cgctaatgtg tctttaaatg gctgattagg
    19681 cagccagctt tctaatcgcg aaacttgtga ttgctgtccg taagtttgag aagaactgta
    19741 aaataagatt ataacgacta tcagtgcgat tactaaataa atatttccgt ttttcatttg
    19801 tttttttgaa gaattcataa gtcacctctg tattttatct tagacttttt ttgaagaaac
    19861 aacaatcatt ttcatagaga cttcttccat aaaaaagtgc tatacttaat tttgtattac
    19921 aatatgaagg gagttttttc atgagttatt cattaaattg gaatctagat tctatttttt
    19981 ccggaggcag tcattctgat gctttgaacc aacggatgaa gcaattggaa gaccaaatga
    20041 acgagtatta tcaccgcgta acaaaatggt cacctagttc tgacaatgca gagcagttaa
    20101 acgctattct tcaattgcaa gaaacgatta cgaatggttt tacccaatgc agcagctata
    20161 ttactgcatt gctttctgcc aatgtcaatg attcagatgc aaaggtctta tcaggcaagc
    20221 tttacgcaat gctgcctcgt ctgcaatcag ccgaaactgt attgtcaaag aaatttgcag
    20281 aaatatctga caatgattgg aatcagatgc tttctcaatc ttcgtttgaa acaattgctt
    20341 ttcgtttaaa cgagattcgt cgtgatggct cacaattatt atcagaagct gaagaaaaca
    20401 ttataaatac gctttcttta gatggtctaa atgcttggag cagtcattat gatacgattg
    20461 tagccagcat ttcgattccc ttcgaacaag atggacaagt agtcgaatta tctgctggac
    20521 aagccttcaa taagatgatg ggcgatccag atccaaaagt cagagaaaca cttttcgcag
    20581 catgggaaga agcctggaaa gaaaaggcac ccctcttcac ggatactttg aatcatttag
    20641 atggttttag actttctgac tatgaacttc atggtgtcac agattttcta caaaaaccat
    20701 tagagtacaa tcggttgaag aaagaaacat tgtctgtcat gtgggataca atccagaaaa
    20761 acaaacaacc ccttgttaat tacttgacta gaaaagctaa tcttttcggt aaagaaaaaa
    20821 tggaatggca agatcaagat gcacctatta ttttaggcga tttgaaagaa aaaaccttta
    20881 gttttgacga agcagcagca tttattatcg aaaactttaa caaattcagt ccaaaaatgg
    20941 ctaaatttgc ccaatctgct tttgaaaaga gctggatcga agcagaagat cgtcctggga
    21001 aacgtcctgg tggttattgt actgagttac cagaaacaaa agaatcaagg atctttatga
    21061 cctacagtaa ttctgttaat gaggttgcga cacttgctca tgaactagga catgctttcc
    21121 atagcagcac gatgtgggat ttaccttctt taaatcgcga atatgccatg aatgtcgcag
    21181 aaacagcaag tacattcgca gaactgatcg tagccgatgc tacattaaaa gtcgcaaaaa
    21241 caaaagaaga aaaaatcaat ttgctagata caaaactgca aaatgcttta gctatgttca
    21301 tgaatatcca ttcccgattc atttttgaaa atcgattcta tgaagcacgg caagaaggat
    21361 tagtctcaga agataagatc acagagatga tggttgaggc gcaaaaagaa ggctatcaag
    21421 gagctttagc tacttaccat ccatatttct gggctgcaaa attgcatttc tttattgatg
    21481 acgtaccgtt ttataacttc ccatacacat ttggctacct ctttagtttg ggcatctatg
    21541 cttacgccaa ccaaaaggga gcaaattttg aagaagaata tatccattta ctacgcgata
    21601 ctgcctcaat gacgacggaa gatcttgcga agaaacattt gaatgtcgat cttacccaac
    21661 cagatttttg gcaagcaggt atcgacatgg tgactgaaga tatccaaacg ttcatggaat
    21721 tgacagaaga atttatctga tttctatttt atcacaataa aaaaagagtt agtccagaat
    21781 gggctaactc tttttgatta atcattctta catgctgaca gcaaagtcag gggcaaacca
    21841 ttgaactgaa ccaactttta cgctttcgcc tggttgagga gcatggatat attgtcctcc
    21901 gcctaaagca atcgctacgt ggtaagttcc gccttgtgac ccccagaata acaagtctcc
    21961 agcttttgct tgagaaactg aaatttttgt tccagctgat tcttgaggaa ctgtccaacc
    22021 accgatgtca cgaccagtta cttgcatgta aacatagcgt gtgaaccctg agcagtcaaa
    22081 gccacttgga tctttaccgc cccaaacata tggagtacca atatatttgt aagcttctgc
    22141 tacgattgct gcaccattca cacttccaga aggagctgga gcaggtgtta caggttttgg
    22201 ttgttcaggt gttggtgttg gcgttggagc cggagtacta cttcctgtgc cgtttcctgt
    22261 atcaacactt tgatctgttg atggtgttgt aggcgcaggt gttgttgatt cttctgttgt
    22321 tgaagattca ggcactgttg ttgattcttc tgttgctgaa gattcaggca ctgttgttga
    22381 ttcttctgtt gctgaagatt caggcgctgt tgttgattct tctgttgctg aagattcagg
    22441 cgctgttgat tcttctgttg aagattcagg tgttgttgat tcttctgttg ctgaagattg
    22501 tgtagctgat gatgattctt cagtcattga agattgtgta gctgatgatt cttctgttgc
    22561 tgagctttgt gcagtagatg aagcttgagt agcttgtgct tcagcctctg cttgttcgcg
    22621 tgcttctttt tcagcttttt cttgtgcagc ttgttgacga gcttgttctg ctagacgttg
    22681 ttgttcacga atacgagctt gctctgcttc agcttctgct ttttgacggt tcaagtcagc
    22741 tttcttgtct tcagcagttg cttgttcagc agctaatgaa gttttcagta cgttcaaatc
    22801 agcttgttta gataaaagat cgcctttttg agattccaaa gcagcttggt tttcagctaa
    22861 ttcttttagt ttagcatcgt tttcagcttt tttgtcttct acagcttttt tatcttgttt
    22921 ttgttgttcc atcaagtcgt tgtttgcttt taccatcgtt gtcattgctt gaacgcgtcc
    22981 aatagcatct gctaatgaat cagcattcaa tacagcatcg atgtagtttg agcttgtgtt
    23041 gcttacttgt gcttcgcgtg cttgtttttg gattgtatct tcacgttttt caatacgttc
    23101 ttgtaaatct gcaatgtctt ttactaattg tgcagattct tgacgcaatg tatcttgttt
    23161 tgctaatagg tcttgtgctt gtgtgttgat ttcagaaact tggctttcta aggcatcgat
    23221 ttgtgattgt gcatctgctt gttgattttt caagtctgca atcttttgat cttgctgttg
    23281 tatctgagaa tcaaaatcgt ccgccgcggc agcgatcggt gatgctacgg cagtcaaggt
    23341 cattgaacat accattactg ctgatattaa actctttttc actcttcatt cctccgactg
    23401 gcttaattta ataaatatct aaatatattt aagtctttct taacgatata aaaattgtac
    23461 catagcagtg tgtcaacgat ataatagtta tgttacaaaa atgtttcaaa acaactttta
    23521 aaaatgacaa aactgttcgt ttcagaaaat gatcatgaaa aagccgcgtt aagtctagca
    23581 tttcttaaga taacaacgat tctttttcgc tttcgaccta aaaataaaaa aagaaattat
    23641 tcatcactga ataatttctt aaagggaaaa atgaataata caaatataat catgttcaac
    23701 agcagtgtag gtcctaaaaa ccttgtaata aaatacgtgt tatttactac tgctaattta
    23761 aaaatcaact ggaccaccat cgtaaacaat tcataacccg tgacaaagat gatcatactg
    23821 aaaaattcag taaagatgtt gacatggata acgtctttca ttacatacat caaccataca
    23881 attaaaggga gagctactgc atagataccg ataacgccaa tatagtaagc gtcatagata
    23941 gccccgagaa caatcgtggt aatcagtaaa taacgttttt caaacgccat actgcaacat
    24001 aataatgcca atatcagaaa gtgggcattt gacatatagg tgcctttcga ccactcccct
    24061 agcattcttg ttaaatgacc atctatcaac atcaaaaaga acaaaacgat tggcagatag
    24121 tacttcattg tttctttctt caacatggac taatcctccg ctagccgttg gacaatcgtc
    24181 acaactgaca cgtcatacat ttctgcataa ggtttcacat aaacttcccg atccagccca
    24241 taactatctg gtttcgtttt aataaccgta ccgatcggca agttagctgg agaattccct
    24301 ccaagaccgg atgtctggac aacatcccct tctttgatat ccgtatcacc agttaattgg
    24361 gtcaccacta aggcatggag cttttcatca tagtttttaa gcaaaccaaa cgcttcgcca
    24421 ttagccgaag atacccgtac tggaaaatga ttggagcttt cattagagga tgacagtaat
    24481 tcgattttag acgaagccgt attgacctcg atcactcggc caatcaatcc tttttgcgac
    24541 atgactgcca tatttgcttc gataccgtct ttagaaccct tgtctacgat cagcatgtcc
    24601 tgccaactgt caggcgaacg agtaatgaca tttgccgtta ctttttcgta actagtcagc
    24661 gtctgattca actcaagttc ttttttcaac gcttcgattt ctctctcgta attcttgttt
    24721 tgctgtgaaa cgtcatcata gctatcgatt ttttctttta gccgctcatt ttcggcataa
    24781 gttgaaaaaa gattatggac agaatctact ccatttcgta cccaccgtac tggggcagag
    24841 attgttttat caaccattgc aacactgtca ttaacgatgg attggaagaa attgggcttt
    24901 ccttcattcg ctcgctgcgc agcggtcaca cttagtatcg tcaccacgat gataacaata
    24961 accaaggtaa taataatatt tttattagga ttgaacttct tcacaaagac acctcgaatt
    25021 aattagactc ttgtgttcaa ttttatcact aaatgccgtg aaacaaaagg taagttgctc
    25081 ctcttaagct tttttttagc aaataataga ttctgtcatt tttagcctga aagacaaatt
    25141 tttttatttg tttatggatc aatctttgct ttgaataact gcaatcatac catctgaaaa
    25201 agaaaattct gcggtatctg aaagaaattc gttacttgca taagatgtcg gatattctac
    25261 ttctttattt tccaatacat acttgctgcc ttttaatgta agattcgaga cgggagtcaa
    25321 gcagcaataa gctaaatact tcatatctgg tatctgtctt actatatgct ctccaggcaa
    25381 ataataagac aaataatttt gacaatctct gataataagc tgatgggcaa agggtttgaa
    25441 gcgaggttcc atacctaacc agagattggc taaaagatga tccaatcttc cgcccgtagc
    25501 tccaatcaaa gtgacttccg cttgcgggta acgttcaaat gtttttaaga tacctaactg
    25561 tgtatctgta tcgtcttttt ctgcagggga acgggtatac tctttggctt ttgcaaatac
    25621 ttccttctgc tcttcgttcg acaatgaatc aaaatcaccc actgccagat ctactgggta
    25681 gcctgcttga agcaggtaca gcgcaccacg gtctatcccg acataggcat cgtatttgga
    25741 cagcagagac tgcggccagt tttgcggatt acctccagca gctaataaaa ttttcattta
    25801 gtctaatgcc tcttttaatc gttcgatttg tccgactgga ttttcggctc catagatata
    25861 tgatcctgca acgaagacat ccgcccctgc atctttacag atttttgctg tttctggaac
    25921 gattccgcca tctacttcga ttgcataagt ccaattgttc tctctacgta gatcagcgag
    25981 ttccgtaatt ttttctactg tttcttcaat aaagctttgt ccgccgaacc caggattgac
    26041 agtcatgact agtacttgat cagccaaagg caaaacatgt ttgatcatgg agactggtgt
    26101 tcctggattg ataactactc cagctttaac tcctaagctt tttgtcattt gaagtgcccg
    26161 atgaatatga ggagttgctt cgacgtggac agtaatgata tctgctccag cttttgcaaa
    26221 tgctggaatg tagttttctg gatcaacgat catcagatgg acgtctaacg gtaatttagt
    26281 aacaggacgg attgcctgaa caatatttgg ccctaatgtg atatttggga caaatcggcc
    26341 atccattaca tctacgtgga tgtaatctgc gcctcctttt tccactaact caatgtctct
    26401 ttgtaaattg gcaaaatctg cactcaaaat ggatggtgct atcttcattc ttgtttcctc
    26461 ctattttcgt ttaccttctt tttttgcata cattggtttt cttttttcga tttcttgtaa
    26521 gaattgcaaa taattgtcgt aacgtgtctg tgcgatacca cctgtttcta ctctatgttt
    26581 tacttcgcag ccaggttctt tagcatgcat gcactctcta aatttgcaat ggacagaagc
    26641 ttctacaaat tcaggaaatt gtctcggcag ttctcctgct tcaattgtca aaaagtcaat
    26701 cgagctaaat cctggtgtat ctgctactaa cccgccatag ataggaatca gttccacatg
    26761 acgtgttgta tgccgtcctc ttccaagtgc atcagaaatc tctcctgttg ctaaattcag
    26821 ttccggtgat atttgattca gtagcgtcga ttttcctgct ccagactgac ccataaagac
    26881 cgatagccgt tctgggaagt aacggatcag ttctgtcgta tcacccgtat gattgggtac
    26941 aatcaccgga tagcctattt tagtataggt ttgcttgatc tcttcgattt tttctgggtc
    27001 gtctgacaag tcggtctttg tcaaaaaaat aatcggttcg atcgactcgt attccaaggt
    27061 aactagaaag cggtcaagta gattataaga aaatgcaggc tctacgatac ttgtgacaat
    27121 gattccaaga tcaacatttg tgactggtgg gcgaactaat tgattttttc tcggcaagat
    27181 ttccagaaga tagccgtctg tttgattttc actctcaaag atcacctgat ctccgacaag
    27241 cggcgtgatt ttccgattcc ggaaatttcc tcttcctctt gtttgatagg tctctccgtt
    27301 tgcgtataca tagtaaaaac cgctgattgc ttttctgatt tgtcctttga taagtgccac
    27361 ctccgttttt gtttatttta ccatacgaag aggaaagtag gtgttattcc atgcaaactt
    27421 ctcaaagtat atggcttgaa aattgatcaa aagagataga aacacaaaaa agagaatgca
    27481 acaaatcaat gtcgcattcc cttctgatat attttattca gcacttattt tgaactttct
    27541 gaggtgctag ctgatgaact tgtggagctg gaagattctt cttttgaaga gttgcttgtg
    27601 ctactggagc tacttgagct gctagaactg tctgaagagt ctttttcaga actagaagac
    27661 gctggatctg gtcctttaga gtaaattacg ttcacaacca ttcctttggt aattgtcgtt
    27721 cctgcccctg gtactgtacg aatcacttta tctttatcca ccgtgtttga atattcggaa
    27781 gtctcatgcc cgatatattc tgcaccgaca ctagctaaat aactttgtgc ttcgcttttt
    27841 gtatagccgg agatatcatt caatttaggc tctgttcctt ggcttacgac aaaattgatg
    27901 taagtttctt ctgctacaac ttcacccgag gctggatcct gactgatgat cgaacctgat
    27961 ggtacagtgt cgctatagtc ataagtagca ctaatattat tgatattgaa tccttgtgta
    28021 acaagccaat tacgaacagt ttcgtagttt tctcctacat gactactcaa agtcactgtt
    28081 tctggtcctt tgctgactgt gaaagtaatc gtgtctgttt taggatcgac ttctgtatct
    28141 tctgatggag attgcgaaat gatcattccg ctttctacct ctgaactgaa ttcctcttct
    28201 ttttgaatca agtcagcaga aaaccctaat tctttcaaac ttgcttcggc atcttcataa
    28261 cttttaccac tgtaatcatc taatttgatt tttttcgtgc cgctactaat atacagagtg
    28321 acttcgcgtt tttgcttgac tgtcgttccc gctgccgggt ctgtcttcac tacattacct
    28381 tcttcgattt tgtcatctgc aatttcttct gtttttgttg ctacttctaa tttcgctttt
    28441 gcgagtgttt ctctagcaga agcttcagaa agatcagaaa catcaggaac aacaacttct
    28501 cctcgcccgc cagaagcaaa gaatacagct gttccgattc ctaaaacagc aagaatagct
    28561 aataggatca gccaccattt tttctgtcct ttctttttag gatcaggcag aacttcttcc
    28621 tcctctggta aggtttcgtt ttctggcttg tcttttggca gaggcataga tttgaatgaa
    28681 tcaggcattg gtgcatcttc cgtaaggggt gtgataactt ttgtttcatt atccatcaca
    28741 tgaggctgcc atttttcttc gtttgcacga gctggtgata atactgtaga aagatcatca
    28801 gacatttcct cggctgactt ataacggtct gcaggttctt tagccgttgc ccgtaaaatc
    28861 acgttttcca gtgcttgtgg cacatttgga tcaagtgctt ttatagatgg aagatcatct
    28921 tgaaaatgtt ttaaagcaat tgttacagca gattcaccat caaacggtac gctacccgtc
    28981 aacatctcat aaaggatgat ccctaaagca taaatatctg actgcttcgt tgccatactt
    29041 cctctggcct gctcagggga cagataatga acagatccta gcatcgtatt cgtctgcgtg
    29101 atcgatgttt cagataaagc gatagcaatc ccgaaatccg tgatttttac aacaccttca
    29161 ttatcgatca gtacgttttg gggtttcaaa tctcggtgga tgatttgatg gttatgagct
    29221 aaagaaatag cagaaaggat ctgctgcata atatttactg ctgtttcata aggaacagga
    29281 taatgtgttt ggatatatcg tttcaagtcc attcctttga cgtattccat caccagatac
    29341 tgcatgttgt cttcttcacc aacatcgtaa acactaacaa tgtttggatg aacgagttct
    29401 gttgctgcta aagcttctct ctgaaatcgt cgaatcgcag tctggtcatt ttgaaagtca
    29461 aatcgtaaga ctttaactgc tacatcacga tccaagatta aatcgtgcgc caaaaataca
    29521 tttgccatac caccgctacc gatatttcca gtgatttgat aacggccatt taattttttg
    29581 cccaactcga tcatacactg tcctccttat attcgataag aagaacggtg atattatccg
    29641 ctccgcctgc ttcattggca cgatcaatca gctcagttac tttatgagac aatgggcctt
    29701 cttgattgat gatcgttcct atttcttctt cagacagcat gttcgtcaag ccatctgaac
    29761 ataacagcag tcgatctttt agttgccaaa gatgagtaga aacatctact tcgactgttc
    29821 caggcatgcc gacagaacgt gttaaaatat ttttccttgg atggttcact gccatttctt
    29881 cgctgatttc tcctgatttg actagttcat tgactaaaga atgatcctcc gtcaattgca
    29941 tgattttatc ttcacgaatc aaataagctc tgctatcccc aacattggca atcgtgaacc
    30001 agtcatctga cagagcggcc gctacgattg ttgttcccat accgttatat tccggctgtt
    30061 cttgtccacg ctgataaatc agcatatttt cttcttgaat cgattgaatg aaccattggg
    30121 cgattttttc atcgtcaaca gcttcttgtt tttcccaagc ttcgcctaga ttcgttaccg
    30181 ccatctgact ggcaatgtct ccggcacgat gaccacccat cccgtctgct aatacagcaa
    30241 gcttgagacc tgaacggctg gtaaatacac tggcatagtc ttgatttgtg ttacgtcgtc
    30301 ttcctacatc tgattgatat tcaatctgca ttttttcacc tcattacttt ttgcgcaaac
    30361 aacaaatgaa aaatccatct gtgtaaaact gatgcggata caaagtcaac attttctctt
    30421 cgattgatga ttgtagcata ggattggtca aaacatcaat cctctcaaaa tcagggtgtc
    30481 tttccaagaa agcagaaaca acgtcttggt tttcttcttt taagatcgta caagtgctat
    30541 aagtcagaat accggaagac tttaaagttg gtgcgcagct ttctaaaatt tccaattgga
    30601 tttttggtaa attcgctaat tcatccggct gttttttata acgaatatct ggttttcgcc
    30661 gaagcagccc aagacctgaa caaggcgcgt ctactaaaat ccgatcaaac tgctctgctt
    30721 cgaactgttt actgacttct ctagcatcca tcttttgagc gtagacagca gaagagacac
    30781 ctagacgtgc tgcattatct tcaatgagtt tgactttgtg ttcgtgtaca tctaaagcga
    30841 ccacttctcc accgcatgac ggatctaaaa aagaagcaat atgcgtcgtc ttacctccgg
    30901 gtgctgcaca ggcatctaag acatgatgtt caggctcgat ttgcatagac ggcgctacaa
    30961 gcatcgaact ttcatcttgg atcgtcatga cgccatcgtg gaacaatgag ctagaagcta
    31021 aatgcccttt tttcgctact ataccgtatg gactgacttg gcttttttca gctgtgatct
    31081 cttcttcttg caaaacagtg atggcctgat ctctggaaag tcggcgtgta tctactcggg
    31141 cactagcatg gctaggctga tatagcgata aaccgagctt ttcagtttct tcgtatccga
    31201 tttgatccac cagtcgtttc gtcatccata gaggcaggct gattttgaca gaaagtcttt
    31261 cgataggatc agcaatgcct tgcagatctg gtgctccttg acgctgataa ttcctcaaga
    31321 caccatttac aaatttccct gtcccaggat ttccttttac ttttgcgatt tcgaccgcct
    31381 cgtttaaaat agcatgtgca gggactttat ctaaaaattc taattggtat acagaaagat
    31441 aaagaagcat cttgacccag tcatccactt tttttgcttt agcgatcaat ggtgcaacgt
    31501 aaaattccaa tagtcgctga tggctaatcg taccatagat caattctgta aataaaccca
    31561 catctttttg atttagctcg ctttgtttga tcatctcatt caacaaaaga ttcgagtagg
    31621 cgccaccctt gttcactcgc tctaatgtca gtaatgccat atatcgtact gattttttca
    31681 tttttttagg aatttttttc attatttcac ctgctgacca atctgaactt gctgaccgct
    31741 tccgttaagg aaatcatgta cggcctgttt tcctttacca gctggctgta attcattgat
    31801 ggctaagacg gtctgtttac cgcaagcaat ccatagattt tttttgtctt tccggatgat
    31861 cgtaccaggt gctttgtctg tagtttctgc caatacttca accgataata atttccagcg
    31921 tatgccctca taggtcgtga atgcaattgg ccaaggacgc attccgcgta cttggttgtc
    31981 aatttcttct gcagttttat gccaatcgat tgcttcttgt tcccgtgtga tgtttggcga
    32041 aaaagttgct tctgactcgt cttgaggtac tggtttttgt ccatccaaaa tattgggcaa
    32101 tgtttctagc aatagctttc ttcctaaaag gctaagcttt tcaaacatcg tccctacatc
    32161 atcttgttta gtgattggta tgctttcttg cgcatagatt ccgcctgcat ccattttttt
    32221 gatcatttcc atgatcgtta caccagtttc tttctcccca ttcatgatgg cataatgaac
    32281 aggcgcacct ccccgatatt taggaagtaa agaagcatgg acattgattg cccctaattt
    32341 tggtacttgc aataactttt caggcaagaa ttggccaaat gccgcagtga cgatcacatc
    32401 aggcaccaat tcaatgattt cttccatttc tggcgaaccg gagattttct ctggctgcag
    32461 cacacggata ccgtgcttca gagccgcttt ttttaccggt gtcggcgtaa ttactcgttt
    32521 ccgcccaact ggacggtcgg gctgtgttac cactgcctgg atctcgtaac ctgattctat
    32581 cagcccttca agaatcggca cagaaaaagc aggtgtgccc ataaatacta gcttagtcat
    32641 caagatgttc ctccatatat tcttcaagtt cttcttccgg gatctgctgt atcattttct
    32701 caatgaacaa gataccgtct aagtgatcga tttcatgctg gaaggcacgg gctaaatagc
    32761 caaaagccgt cacttctatc tcttctccgt ctcgatcata ataacgcacg gtcacttcat
    32821 ctgctcgctt gaccgttcca tagacatgcg gaatactgag acaaccttct acgtcaaggc
    32881 tttcaccttt tgcttcgatg atttctgggt taatcagttc aaatttctcg ccttcatcta
    32941 cttcgatcac agcaattctc ttgttttgtc ctacttgagg agcagcgatc cctattccgt
    33001 cattcgcaat cattgtctca tataaattgt ctaataaagc gattgtctcg tccgtgatta
    33061 catcgattgg ctgagcagtt ctttttaatt tatcattagg gtggatcaat ataggatagc
    33121 gcataatttg gccctttctt aaataaagtt taatggttcg ttgtcaattg ccacaaaaag
    33181 accttgtcgc tgttctttct ggcttccatt caaaatttca tccaaaacat gaggaagatt
    33241 cggttcatgt ttatatttga tgattagttg ataataatat cggtttttca ctctcaaaat
    33301 catgctgggc gttggcccta atagcaagct ttgagggctt aacacttctt ttagctgatt
    33361 ggcaatctga aagattttct ttgccgctac ttgttcttca ggatggctgg cggttatttt
    33421 cacagtaaag taataaggag gatagcctcc acgatgccgt acatgcattt cctgctgata
    33481 aaactgctca taattttgtt ttttagccaa ttctatggcg taatgttgag gattgaatgt
    33541 ttggatcacg acttcgcctg ctttttccgc tcgccctgct cgtcctgaaa cttgggtaag
    33601 caattggaat gtatgctcac tagaacgaaa atccggtaaa ttcagggagg tatcagcatt
    33661 caacacccca actaatgtca cttctggaaa gtccaaacct ttagcaatca tttgtgtccc
    33721 taataatata tctgcttctt ttgcaccgaa tttttgtaaa atctgttcgt gtgccccttt
    33781 tcttcgagtg gtatctacat ccatacgcaa aatcctagct tgcggataaa gttctcggag
    33841 ttcctcttct actttttgag tacctgttcc atagtagcgg attttattgc cgccacaatt
    33901 aggacagcga ttgggaatag gttcttcatg tccgcaataa tggcagcgca ttgaacgtgt
    33961 atccatatgc agtgtaagag agatatcgca attaggacat ggaagaacaa atccacagtc
    34021 cctacacatc acaaaagacg aatatcctcg acgattgagc agtaggacag tttgttcttt
    34081 tttgtctaat cgattttgta ttttttcctg caaattagca gaaaaagtag aggtccgatg
    34141 attctgaaac tcttcacgca tatctacgat ctcaatagct ggaagctgtg cagctgcttt
    34201 ggctcggtgg tttaactgca ataactgata aacgcctttt tgagctcgtg ctcttgattc
    34261 taaagagggc gtcgcgcttc ctagaactat tgggcaatga tgatatttac tgcgccaaat
    34321 tgctagatct ctcgcatgat aacgcggtgt ctcatcttgt ttgtaacttg attcatgttc
    34381 ttcatcgata atgatcagcc cgatattttt cagcggggca aaaatagcag atcgtgcgcc
    34441 tactactact tgcgcttctt cccgctcaat cttgcgccat tcatcatatt tttcaccttg
    34501 ggaaagtccg ctatgtaaga ccgcaactga ttctccgaag cgtcctttga atcgctcgac
    34561 catttgcgga gtcaatgcga tttcaggcac taacataata gccgttttat tttctgacaa
    34621 aacatcagcg attgcctgaa gatatacttc tgttttcccg ctgccagtga ttccctccag
    34681 caaaaagacc tgatcttttt gctgctgacc tgctgtgatg atttgttcga cagcattttt
    34741 ttgttctgca ttcagttcca atgccgtcgt ttggtcaaat actcggtctt tataagggtc
    34801 gcgataacgt tctgattcta taaactccag ccagcccttt tcttttcctt gattcaagac
    34861 agcagtactg attcctttat ttttgaaata agcaattggt tcttcttggc tcagttcaga
    34921 taaacacaaa agaagttctt tttgtttctt ggcattttgc cgtaattttg cccattcttc
    34981 ttcgatttgc ttttcagtta acaaagaacg gaccaaacga atcgttttta ctttatttcg
    35041 tgtatggact tcatatttga tatctactaa ttgctcttgg cgccagcgaa tcaattgaga
    35101 aaggctgcct tcttcttctg cttccttcca ggaaatcact tctcgctgat caaacaatac
    35161 ctgaacttct ggtgtgtctg ccaaaggata gatcaattta tcatattctg ctttcatcac
    35221 actcggaagc atcgtttgta gacaagtgat tttgaatgcg taagtaattt ttttcatata
    35281 atcagctaat gaaagtaatt cttcattgac caccggagca aggtctagca aacgaataac
    35341 tgccttcaaa gatggattag ctgattcttc tgatttttgg atagccataa caaatccttg
    35401 gacatgacga ttgccattac caaaagggac ttctactcgc atcccgactt gcaaagctgt
    35461 ttccatttca gagggaacca aataagtgaa tggctgatcg gtctgcatag taggtacgtc
    35521 cacaatgact tcagctgtta atgtcatggt tcgtttcctc ctttttttgt cttttcttat
    35581 caagcgacaa aaagttcctt gcctatttta ctagagatcg atggatttgt cttatcttct
    35641 gccaaatcct aacaaaaaat taacagcaga taagaaaaaa aagaactgtg tcaaaaagtt
    35701 cagacacagc cttttctacc agacaataag tggcgaatgt ttgaaaagga aacagctggg
    35761 tttgcttttc tttttagatg ttcgctctat ttttctttat tacatttttt gctcttcacg
    35821 gatacgtgat tccaattcgt gttgttcacg ctctttttgt gcttgacgtt cctcttcttc
    35881 catcttcaaa cgttcacgtt ttaattcagg atgtggatca ttgactacat ttcctgcatc
    35941 gatttcttct aaagcttgac cgacgctttt tactgaatca aaagaatcta gagtaggctg
    36001 tgcacttgca tccaattcat gcgcgcgttt acttgctaaa atcactagag aatattttga
    36061 atttacacga tctaatagtg agtcaattga aggttttaac atcataagac tacatctcct
    36121 ttaacatttt aatatattta ccgattacgc gatctactcg aaaatgttca ctggcaataa
    36181 tgtttttgat tcgttcaact gctagcggca cttcatcatt tacaacagca tagtcgtaaa
    36241 gagccatcat ttcgatttct tcttttgcaa ctttcattcg tttttcgatt acttcatctg
    36301 catctgttcc tcggcctacg atccgtgatt ttaattccgc taaatctggc ggagtcaaaa
    36361 agatgaatac accatcgggc actttttctt tgacttgttt tgctccttgg acttcaatct
    36421 ccaagaaaac atcttttcct tcatccaatg tcttgttgac atatgacaaa ggagttccat
    36481 aataattccc gacatattct gcgtattcca gcatctctcc agcttcgatc attgattcaa
    36541 actcttcttt gcttcggaag aaataatcaa cgccttcgac ctccccttca cgcattttac
    36601 gggtagtcat tgagatcgaa tactgaaaat cattatcctc actctcaaaa attgcttttc
    36661 gtactgtgcc ttttcctaca ccggatggac cagacaacac gattaataat ccacgctctg
    36721 acatgacgac gtcctttcaa ctagtctttt tgtacttatc gtttattttg cacttttttt
    36781 ctgcaacttt caaggttatc tttaattata gctagaaatt ggtaaaaaag ctaccctgta
    36841 ccaagaggtc gtaaaaaagc tgtcctgcat caagtaataa gaacagccaa acataaacag
    36901 cttctcatgt ttttcgtttg gttggggtta ttatcgcaga tgcaagcttt tgaacgccgt
    36961 gtataagagg tcgtgaagaa gccgattagt ttcgagtatg aagaaaaatt ttgtgaaaat
    37021 agtttctcac atttttgcat aaatttggct taataccgag aaaatggttt ttgaacatca
    37081 cttattcaaa ataaaaaaag attgtgacac gaattttgtc acaaccttta aatgtattcc
    37141 tagagcaaag aagctaagcg aagaaatcca attctgttta tttattgtat ttctttgttc
    37201 agcatccttg ctaaaagccc atattggaca aagtattcac tacacccatg atctcatctt
    37261 ttcgagaacg tgctttttct gtcggatctt ctacctcttc tgtgtcaatt cgaacaataa
    37321 atttccgatt catcgtcacg taagcaccgt cgttgatcaa aataaacagt tcgttctcat
    37381 tatagtctgc acaggcatct ttccatacgt caaagccgtt tttttcagaa gggatatccc
    37441 gtttaaccac agtttttcca cttaattcgt ggaacgttac gtcataatat ttcattatct
    37501 ctacctcttt cgtcattcaa tattttgtac ttgttctctg attttttcta agatcgtctt
    37561 agactggacg acttgatttt taatttcgat tgcatttgat ttggaaccga tcgtgttgat
    37621 ttcccgattc atttcttgga tcaggaaatc taattcccga cctacaggac attgtgcttc
    37681 gataagttca tctagttttt gtacatggat cgccagacga tccagttcct cgtgaatatc
    37741 tccgcgttcc aacaagatgg ctagctccgt caacaaccgt tgctcatcga ctttcgctcc
    37801 aagaaattcc tccagctttt tttgatacct tatttgaaat tccttttcat agatttctac
    37861 aaaactatcg agttttttta gtacttcttt gaattcttca gtattctttt tcaacactaa
    37921 agctaaagct tgaccttctt tttctcgact cgcctcaata gaatcaagtg cgcttttcaa
    37981 tgtatctaga gctaactgtg ccaattcttc catgctctct tccggttttt cttctaccgt
    38041 tacgaagttt tcgtccagca cgaagcgttc cgccatccga ctaattgaca cttgattttg
    38101 actaccgtat cgttgttgaa ttccgtctgt caattgagtg ataagtgaat caatcaattc
    38161 ccagttgatg acgatctgtt tttcgttttt gccaatataa gctagattca caaatacttc
    38221 gattcgaccg cggcttaact gctgtttaat aagctgacga aaatcgtttt caacaaagtt
    38281 caggatttta ggacttcgta tttgaacatc tagaaaacgc tggttgacac tttttatttc
    38341 aatatctaac tgatacgctt ttgtttcgcg gatggctttg ccaaaaccag tcatactttt
    38401 cattcgacag ggtccttcct cattacatat tttctattgc tttttgcagt tgttcaaact
    38461 cttcgttcgt caatgtcagg cctttcccca ttttttcatg gtctggcgcc caatctcgaa
    38521 gatcgaattt tggcgggcga ccattccagc tgactaggtt cagttcttta cgccacccct
    38581 tgttgttttc tgacaatata gcgatttctt ctacgatttc atatgaaaat tcttgtgcca
    38641 tggttgttcc tccttgagat aatataaata taggatcagt aatgtgtcaa ctggttgctt
    38701 aagcaattca tgctgcaaac gatccttgcg ttttccttgt agcagataat caaaataaac
    38761 agttttcgtg cgctcatttt gtattttttg ctggtatttt cgataccttc gccattcttc
    38821 agtacttaat tgaccaattt gtgccaataa atcatccggc atacttttta tatcttgttg
    38881 gcagatcatt tgaatcatca tgtctacttg atagatttca ttgggcagta aaaaatgttt
    38941 ttttgctaaa agttctagca tcgccaatcc gcatgtctct ggtacgaccc tgttcttata
    39001 taaattacgc agtttttgcc aaaattttat gcttttgaaa aaagataatt ctaactgaat
    39061 ttcttttgtt aagtaagaca aaaatcctcg ccagtatgtt cttgcaggtt taacagaatg
    39121 aaatgtatac cagttcccat agtaatagcc taatcgtttt ttcatttcca gatagcctaa
    39181 ttgtaaattt aattggttcc tttggctatc aaaaagcaga aagctgccta gtgtccacaa
    39241 tgtttgacat ttccaatgga taaaaatgtc tggcatacga atttttttcg ctgggcctgg
    39301 cccttgcaca tctacgacaa atgcctctgt tgctcctttg ttaatcgcaa tatcaatagg
    39361 tattttgttg cgatacccac cgtctgcata tttatttttt ccgatctttc gataagccat
    39421 agcgggataa aatgaagcag aggcgagtat ccaatctggt atttcttctg tttttgtctg
    39481 ttggatatca gtcactactt ccgctagttc tggcagttta gtagacaccg tatataaacg
    39541 tattttggga ttatgtttga gtaaggacaa atccaaattg tctttgacca tcttttccaa
    39601 tggagcagaa gaaaccccgc cttcaattag tgctgttttc gtcatttggc gtctttctcg
    39661 atagaagcgt tcacgaaggt cttcaactgc agccatttct ggtaacgcaa gcacttgtct
    39721 tgtcgacagc tttttccata aattcacagc ttttttcata tctccttgta aaatcaatgc
    39781 gccgttcaac gcacctaccg aggtacctgt gataatctca aagttgatat catgttcctt
    39841 cagcgcctgc cacacaccaa tctgataagc accgtgcgct cctcctccac ctaaaacaag
    39901 tgctgtatga tagaccagct ttttatttaa ttgtgtggtt ccttgatagc cgtttttatg
    39961 aaaaatacgc aaccattctt ctgatagagg agattgaaat aaaaaacaac agttttcttt
    40021 aataaaaaaa cgagcgcaag cttccatata ccgaaaaaat tttttccatt caaaagtttc
    40081 accttcaatc aacagattat taaaaataac atctcctcta cttttagcaa tagtaaaata
    40141 gacggtatat tttttcgata ctgctttaaa agcacattgc ttttttgcag aacgccaaaa
    40201 agcgtctcta ctttcttgat gactttgaaa aaatggaagg ggttgttttg cttgctggat
    40261 aggcgaatac agcgacattt tctgtgaaaa gtaaactttt tttatctcca tcgcgctctc
    40321 ctttttcttc aagtatacca gtacgtcata aaaaggtcat gagtctcgta ttcgactttg
    40381 tagattccat aagaaaacaa ttcataaaac ctcctttaaa taaaaaaata caaaaatcac
    40441 aaaaattaat tgaaaatgag agtgttttca atgaaaacgt gattttgtaa tggaatttta
    40501 aaataaaaga aacaagcttt tttaatgcaa atgttgtaaa ataaaagaga ttaagaggaa
    40561 ataagaggag gaacatgatg actgagtcag tttatgtaca tattgatacc acaagtaatg
    40621 ctgttttaac aaaagggctg actgctactg actttgcaaa cagtatcgtg cattttcctc
    40681 aaaacttgct cttgcttgat ccatctgctt ctgctggaga atatgaatcc catacagggc
    40741 tgaaagtaat ccgtggtaca gaaaatattc agcgtttctt ttcctcttct cgtaacaggc
    40801 gtggattcga tgaattgaag tggatcgact ttactgattt aacgatgctg aaagaattga
    40861 cacctttaga aatttcagaa ttattatatt ttggtcatat gaaaacacat cttcattcgc
    40921 cgttttttta taaactacag aataattttg tatacttcga tcttaatgat cagctgaatc
    40981 ggatttatta tcgctattta gatgaatttt ataggatttt tgctagtaaa ttaagttcga
    41041 tcttgtcaga taagatcaat gtaaaaaaat cttttttcaa aaaagaaaca cctgttgaaa
    41101 aaatcagtgt ggaattattg aaagaaatgc gtaatttgat gcaggaaggg atcatttttt
    41161 cttttgatca agttggtttg atcgatggta aatatcgtat cccaatctat gtgattgaag
    41221 attatatttg gaaattaaaa ggcacccggt atcgagaaga ggaaatcatc gctactttaa
    41281 tctactctgt caccgatcga cactggcaat tggtagaaga tgccgatctt tcttatctgc
    41341 cattgaagta gatctatttc ttatcaaaaa ataaaaagga aacaagaaac taggacatga
    41401 ttctgtctca agtttcttgc ttctttttta tttacagctc ctgtcgttta tctggcacaa
    41461 aaatcgaagg agtcgtttgt tggatcccta ataaaacgat gatcgttaca atagctgtac
    41521 tcaacccgct ggcaccattc attacgaaag aaaagagcca aggattcatc ccccatagtg
    41581 catacgctcc ccagaaaacc actcctgcaa taaaatgcca aaaatatctg gaaagtgcgc
    41641 caatcaatgc accaaacacg atgctttttc taatttgttt cgtattatcg tctacatagc
    41701 ctttttggac atttgaagcc atgagccctg ctgcgcctgc aaaagtatag gcaatcgggt
    41761 actcaatcaa cacttgaacg acacttaaat aataaacttg tcccaacgga aaatgtagga
    41821 tgccccaaat gaaacctgcc agcatccctg cctttgtccc tcttcttaac gcaaaaagag
    41881 tcaatggaat ctgccctaat gaaatagaaa aactgctgcc gatctggatc ggaatcaacg
    41941 acaacaccat cgctaacgct gcaacaatcg ttccttctac ccaaactcta ttttttccca
    42001 taaaaaaact tcctcctttg aataaaaaag tcacaaagga ggaagcagct ttcgaaaata
    42061 gtcaaacagc tgtttattca caattcctac gctcgcataa ccgatacagg tacgaagggt
    42121 ttagaaatag attcaatctc agcccaattg gactcccctt tgtgagttta tttattattt
    42181 attttttgtt tcaaacaatg gactaactgg tttgttttca tggatacgtt tgattgcatc
    42241 tcccattagt ccgccaacac ttacttcatc gattttgtcg attttacgat cttctggaag
    42301 atagatcgag tctgtaacaa ctagacgctc gatagctgaa tcttctattc tttgtaaagc
    42361 agggccggat aatactggat gtgtacatga agcatacaca ctagttgcac cagcttcttt
    42421 caaagcattg gcagccaatg tgatcgtacc tgctgtatcg atcatatcat cgatcagtac
    42481 acaagttttg cctttgactt gtccaatgat attcattact tctgcaacat ttgcttttgg
    42541 acggcgtttg tctatgatcg caatcggaga tttcaaaaat tccgctaatt tacgtgcccg
    42601 tgtgacacca ccatggtctg gtgaaacaac gacaacatca tcgcctttga ttcctttttc
    42661 taagaaataa ttggcaataa gtggcgcacc catcaaatga tcgactggaa tatcaaagaa
    42721 accttggatt tggactgcat gaaggtccaa agtcagcatt cttgttgcac cagctttttg
    42781 aatcatgttt gctactaatt tcgctgtgat tggttcccgt gcacgtgctt tacggtcttg
    42841 acgcgcatag ccataataag gcatgactac gttgattgtt tttgcacttg ctcgtttcag
    42901 tgcgtcaatc atgatcagca actccatcaa gttatcattg actgggctgc tcgttgattg
    42961 aataacatag acatgcgatc cacgaatact ttcttcaatg tttacttgaa tttctccatc
    43021 actaaattga gtaacagatg attttcctaa ctcgacgccg actgctgctg caattttctc
    43081 tgctaatggg cgattggaat ttaacgcaaa aatttttaat cttgggtcaa agtaatgttt
    43141 tgacatgggg acctccactt tctttttcac aactctagaa ttctacctaa taaatagtag
    43201 tcatattttt taaataaatc aagtgatttt gcaaaagtct tagtttagat aagggagttt
    43261 ttttgcatat ccttctttat tgacttgtct tgctctcgca attgccagcg catattctgg
    43321 aatattgtct gtaattgttg acccggcagc aatcgaactg tttttagcta cctcgacagg
    43381 tccgatgata ttcgtgctag aaccaataaa gctgtggtcg ccgacagtcg tatgatgttt
    43441 gttctttcca tcatagttga cgaagacaac accacatccg acattgattt cttctcccag
    43501 cgtagcatca ccaacataag tcaagtgacc gactttagtt cctttgccga tttgagcatt
    43561 tttcacttcc acaaagtttc cgatatggac gttttcgcca atttcagctt ttggtcgtaa
    43621 atgtgcataa ggtcccacat ctgcatgttt cttgacatgg ctgctttcaa tgactgagtt
    43681 ttcaatgacg acgtgatcct caatcctact gtctacgatt tttgaatgtg acccgatgac
    43741 acaatcagaa ccaatgactg tatttccttg gatttgtaca cctgcttcga tcaatgtgtc
    43801 tggaccgatt tctacgcctg catcgatgta tgtcgttgct gaatcgacaa agcttacgcc
    43861 attgaccata tgcatctggt taattcgctt tctcatgatc tcatttgctt tagctaacgc
    43921 gatccgatca ttgactccca ttgattcttc aaaatcatcc gtttgataag cagcaactgt
    43981 atggccttct tcttttaaga tttcgatgat atctgttaga tagtattcac cttgagcatt
    44041 gtttgttcca actttgctta acgcatcgaa caaagcttcg ttgtcaaaac agtaagttcc
    44101 tgtattgatt tcttgtacaa gagcttcttc tggtgttgca tctttttgtt ccacgatttt
    44161 ttctacgatc ccaatatggt cacggatgat tcgtccatat cctgttgggt tttctgcttg
    44221 tgccgtcaag atcgttgcac ttgcattttt tccttggtga tattcaaaaa gattgttcag
    44281 cgtttcagta gtcaataatg gtgtatcgcc actgataact aacgttgttc ctttttttcc
    44341 ttccaagaaa gaagcagctt gcaaaacagc atgtcctgtt cccaattgtt ctgcttgtaa
    44401 cgcatattta ctgcgttctc ctagttgtgc tttaacttgt tctgctccgt gtccaacgat
    44461 cgtaatcact tcatctggtt tcgtttcact gacccgatta atgatatgtt ctaccatagg
    44521 tttaccagaa acgggatgta aaactttata taattttgac ttcatgcggg tacctttccc
    44581 tgccgccaaa ataattgcat aacgtgcgtc caactgcgtc actcctaaat atagtttgct
    44641 gatttcagtt tatcccagta tacccatttt ttcaacaaaa caagtgattt tcttttatcc
    44701 cagcgttttc tggataaaaa aatagataga ccataacggg cctatctatt tggtaaccgg
    44761 tgctctcctg ccaactcctc ggtcacaagt cacactactc ataaaacatg aaaagctgtt
    44821 ttttgaaatc gtttcttgtg acttagagtt aaacggtagg cttacaacct cttcattaaa
    44881 cgtttttcaa tcagctgacc ttcggtatta gctcaataaa cggcaaaata tgaggagcaa
    44941 tttttccgtt tattgagcta atactcagga caggacgctg atttcacaac ctctagataa
    45001 acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgaaaaaa tgtggaaagc
    45061 cattttcaca aaatttttct tactactcga aactaagcgg ctttttcaca acctcttatt
    45121 ctgaaaaata atttcctggc acaaccgtaa tatttttcgt ttgagtatct acatctttga
    45181 cataaagcag tgacgtataa tcatcgatgg cgcgatgacc gttgaatttt gattcggcaa
    45241 atacagtgat gccaacaagt tctgattcga attcttcaat caagctcttc attccgttga
    45301 ctgttccgcc gcctttcatg aaatcatcca ctacaaggac acgtgaacca cgtttcaaac
    45361 ttctcttaga cagttccatc ttttcaattc tttcagaaga tccagacaca tagttgacac
    45421 ttactgttga tccttctgtt atttttgagt cccggcgtac aataacgaat ggcgcattca
    45481 gataatagga cacagcttgg gcaataggta cgccttttgt ggctacagtc attacagcat
    45541 cgattttttc accaaggtat ttagaagcaa tgattcttcc aacttgacgc agcagttcag
    45601 gttctcctaa caaatcagag agataaacat atcctcctgg aagcagacgg tcttgttctg
    45661 atagacgttc tgctagagat tcaatatatt ttttcgcctc ttcatatgaa atttcaggga
    45721 tgaacaatac accacctgca gcacccggga ttgtttccaa ggttccatac cctcgttctt
    45781 taaatgtttt cttgatgatt cccaaatctt cactgataga agatttagca gattcataac
    45841 gttcggcaaa gcttgttaag gaaatcaatt catgcgggtg attcaataaa tactgtgtca
    45901 tgtcaactag acgttcactg cgacgtactt tcacctattc caactccttt taagaaattt
    45961 tatcgtttta cattatataa gtttttcttc aaaaattcga gcattttatg aaaaaataag
    46021 aaaatagttc ggtatttatt aaaataaaaa gaagcctata aaaaattttt cgtttttata
    46081 aggcttcttt tctttataat ttagttattt tttcttctga aggcaaccaa tattcgtttg
    46141 atgatattta caatcaggaa caaagcaata aagactaatg tgattgttgc tcctggaggt
    46201 gtatctagat aaaacgagct agttagtcct gacagcatcc ctagaaatcc tacacaaaca
    46261 ctgatagcaa tcacgacatt gaagcttttg cctaatcgca taccgattgc tgcgggaaga
    46321 accatgattg cggatatcaa aagtgcaccg gcaatcggga tcatcacagc aatagccaca
    46381 ccagtaatca cattgaacat catcgacatc aaatgaacgg gtagcccatc cacgtgggcg
    46441 gtatcttcat caaaagtcag aacatacatc ggccgtttga ataaaaagaa caatataccg
    46501 atggcaacga ataagattcc taaaaagatg acttgctccc atgtaatggt cacgatcgaa
    46561 ccaaacagat aggattggat acttgttgct gaattccctc cgctcaaatt catcaatact
    46621 aacgctagcg ccaaaccacc agccattaaa atggcaatgg agatttctga ataggttcgg
    46681 tagatcgttc gcagatactc caatatcaca gctgctaata caacgactag catggtcgta
    46741 agtgtaggat taaggttcaa aaagaatcct aacgctaccc ctgctaaaga gacatgagaa
    46801 agcgtatcag ccatcagcga ttgtcttctg atcactaaaa acacacctag catcggggcg
    46861 attccggcaa tgaagatagc ggcaagaaac gctcttctca tgaattcata tgaaagcaac
    46921 gccattgaga atcctccttt ctcaccagtc ggatctgtct gtccgcatac tgtttgatat
    46981 cttcatgatc atgggtgatc attagaactg atttcccatg gacatgcgca ctatgtcgga
    47041 gaagacgata aaattcattt ctggattctt catccatacc tgttgttggt tcatcaagaa
    47101 caaataagtc agggtcagta gcaaaaatac gcgctaaact gattcgctgc ttttgtccgc
    47161 cagacaattc acctattcgc cgatttcgca tatcccacat ccctacagct tctaaagcac
    47221 gctgtacatg ttgatgatct ttttcagaga gacgcttgaa ccagcggcct cttggatatc
    47281 ttcctgaacg gactaattcg atcaccgtac taggaaaacc tgcattgaaa gatgcaactt
    47341 gttgaggaat ataaccgata cttaattttt ttccttcttg atttttctca gcaatcttta
    47401 tcattccttt tgaaggtttc agtaatccta acgatgcttt caccaaggtt gacttggctg
    47461 ctccattttc tccagttaaa atgacaaatt cacccgcatc tacatgataa gagacatctt
    47521 ctagtacagg ttcatcatca tagtaaaagg tcaaatcaga tatttcgata taacgcacct
    47581 tacaacctcc attctaaaac ttaattgata ctttctttta aagctttcag atttttttcc
    47641 atgacagaaa tataattttc gcctgctttg atttgttcat tagtcaagct ttctaaagga
    47701 ttcaacactt ctagcttcac tcctgtttca ttcgacaatg tctcagctac cttcgaagag
    47761 gcattttctt caaaataaat cactttgatg ttgtttttct tcacaaattc ttttagctca
    47821 gctaagcgac ttggtgtggg ttcctgatct ggtgaaacgc ccgaaatcgc tacttgtttt
    47881 aagtcgtatt gattcgctaa ataagcaaaa gcagcatgct gagtgacaaa tgtgcggttt
    47941 gttgcatctt ttagctcatc ggagtatttt tgatccagtg cttcaagctt tttgatataa
    48001 gcatcggcat tcttcgtaaa agtttccttt ttatctggat atttttcgcc taattcttca
    48061 gcaatcgttc tgacttcttt tatagctaat accggatcga gccaaacatg tggatcgtat
    48121 tcatgtgaat gaccatgccc ttcttctgat tcttcatgtt cgtctgcttc ttgcgattct
    48181 aaacggtcga ttcctttagc tgcttcgatc atcaaggtct gtttgctatc cactgaatcc
    48241 tttaacgaat ccacaaaaaa ttccatgtct gaactattat acacgaaaac atctgcatcg
    48301 gaaatttctg ctctttcttt tgcacttggt tcgaaatcat gcggctccgt tccagcaggg
    48361 atcaaaagtt tcacgtttcc ttcatcccct acgatctctt ttgtaaaatc atacatcgga
    48421 taaaaagtcg taacgatcgt caaatcctct tttttgtctg cttccttgtt cgtatttcca
    48481 catgctgcaa acagtaaagc acctatcatt accgtagctg tcaaaagata ttttttcatt
    48541 tatatgctcc tttcaatgaa caaatcgtaa ttttacgatt tattaacgtg aactaatgta
    48601 tcaaaataaa aaaacacagt caatagaaat ccatcaattt ctgatttaag catgtatatt
    48661 cttgattaaa tcgtaaaatg gatgagttgc tgctcatatc tagccatttc actacaataa
    48721 aaaactgaag aataccattt taggattcct cagtttttca tcacctattt tacttcttat
    48781 attttattgc agggttcgta ctaaataaac ttcctcacaa aaacctttta acccattata
    48841 tactctctgc gctcttgaat aatgttgaca caaggcaaaa acggttggtc cgcttccact
    48901 catcaatgca gcatctgctc cgtacttgat catacgctct ttgatttgat ggatgactgg
    48961 atgccgcttt cccgttatat cttctaaact gtttcccatt tttttgatca tctgctgata
    49021 atcttgctct cggatggctt cagcaagtcc gtggatgtct tgatgttgga tggcttgcgt
    49081 atctacttct ctaaacactg tacgtgtaga gacactcatt cttggtttga ccaacacaac
    49141 ccagcactgt ggcatagaag gtaatacttg gatttcttcc cctttgccac cgacaaatgc
    49201 cgtacttccg tagacacagt aaggaacatc tgtaccgact tccaaaccga tttctgccag
    49261 ttcttctaac gaacagccca gattccataa ttggttgatc cctcttagag cagctgcaca
    49321 gtctgtactt cctccgccta atccagctgc tactggaata ttcttcttaa caaagatctt
    49381 gacaccggtt ttgatattgt atttattttt tagcaataaa gcagcttgat aaacattgtt
    49441 ccgttcatct accggtaaaa atgctttatt tgtttctaca atgattttgt cttctgttat
    49501 ttcttcaaaa aatagatgat ctgccaagtc tacgctcgac atcaccattt ccaactcatg
    49561 atacccatct tgccgtctat ataatacatc cagtcctaaa tttatcttgg ctggcgcttt
    49621 ttcaatcaat tccatcctct cacccattcg aaaagtctaa gtcgcaagta ttctatcata
    49681 gggaaaaata aaagtatagc ttatgtctgc ctagtggttg attttgtcat cgtttcaaca
    49741 gctttcacag aattttctct tcataatcca aacaagttct agtgattctt ataattctgt
    49801 gagcacttct tctgccaaac tcggaacatt tcctttttct tttcctatca gactgagtag
    49861 ctgcatggta gcaaatccga aattacttcc tttcctataa gcaaaataac gtccttccca
    49921 atgatcgaca tattttaatt tcttttcata agcagactgg aaggaataga aaaaattacc
    49981 ataattatat acgatatgca tgactttttc ttgaaagaaa gaaaaatctg tttctccaac
    50041 attagctaat ggagctaagc ctagattggc ttccgagtag cccattttct cgtatacaat
    50101 aaacagattg gctaacagat agtcagctaa ttcctcagat tctttaggta agacccgcaa
    50161 caaatcatat cccgcctgct tcttcgtcat cggctgagcg gtgatgaagc caacgacttt
    50221 ttgatcttta cggacaatac cgacaccgct agataataca tatgatttat caaatcgtcc
    50281 cacagagaag tatttttctc gtgcaccttg aagccatttt tgtgaaactt catttacagc
    50341 ttgatgtaat tcttccggca gttgatcgta ccaagtaaaa tggtatcctt ctttcatcaa
    50401 acgttgatat tcaagttgct gactcagccg agacaagtct tctgttgcta gatcaacaat
    50461 ccctgcttca cctactttcg tgaagtgaaa acccaattca tgaagcatca ctacgtagct
    50521 ttctgatatc ttataaaacg caagctgata gcctaaacaa tctgcttgtt tcataaactg
    50581 attcgttgct gcccgcatca ttttaggatt gccaactgga tctcctaaaa caaagcattt
    50641 gtttcctttg atctgataac caaaaacgac ttgatcttgg tcgtcttctt ggtaataaaa
    50701 ataactgtaa cctgacaagc gaagctgatg gcttgtagct gtgcctccgt atgtttccaa
    50761 taaacggtca aaacggtctt tttcgtactc actgccaagc ttcgtagtat cttcagctaa
    50821 atattgataa agcgccacta aagctagcaa tgagatgccc aaaccaataa gccctgagaa
    50881 ccacacatca tctgaaggaa acaaaataaa atgatttcct gttattcgac cgactaaaaa
    50941 gcgtccgctg tgatagcctg caattgcgta aacgataaac aaaaagccga acaagctagc
    51001 atcaaagatt atagctcccc aagaataaac gaattttgtt cgataaaatt cttttctgga
    51061 taaccacaca gctaacagaa tcaagacata taccaatatc aactgccaag ataacgtacg
    51121 tgtgattgta tttaaaatac caaaagatag taaagcaatc gtaggcagaa atgccttttt
    51181 gacttttact gaaagtgctc tagcaaggcc gagtaataaa aagccaacca atagattcac
    51241 tgtctgatct aaaaaattga atgagaacgg caataatact tgaaatagcc gactgattgc
    51301 agacagatta gtgattgttg atagaagtac catcatgatc cccgcaaaat agacagcact
    51361 tacgagcacg atatgcgcaa ccttttggaa aaacagtcgc ggaatgttat ctaaaaatcg
    51421 attgattttg actcctgtat gtgtgatgaa caatagaagt cccgtcataa aaggtagaac
    51481 ataataaaac aaccgataat ataatagcca aactactgct acatcttgcc gaacagacaa
    51541 ttgactcatt cctaagatca tcaaaacgtc aaaagtcccc attccacctg ggaccatcgt
    51601 cagcattcct atcaatgtag caatcatgaa cataggatag atcgaaagca tcgaaatatc
    51661 tattctcatc aacttgccga tgatcaaaaa taccgcaagg gctcccgtcc attgtccaaa
    51721 ggatgccagt agcagaccaa gcaagccttt tggataaaac tcgaagaaca atgtctttct
    51781 ctttagataa gcaaaaaaga aaatgactgg tgctaaaaaa ctaccgccga aaagccagat
    51841 ccaatagctt cgaaaaatac tttctgactg aataaaaaag acatcaataa atgtaagaaa
    51901 cgaccataca gacaaaccag tcagcataaa tagtgcgact tttgatacag tggctaaaac
    51961 catttttcta tttgtctgct ttccataaaa actagcccgc agacttgctc ctaccacacc
    52021 accaaaaccg gcgagattgt tgatcgtgtt tgttacccac gcagcaagaa gaaactcttt
    52081 tctttccatt tttggttttc cttgtttttc taagactctg atcgtcaccc aatcatacaa
    52141 caacatcgga gtgacaccca gcagtccagc cagaatcatg agcaggatcg tcatgcggct
    52201 ttgttgtccc atcctttgcc aaatatcttg ccaactcatg ccattagcaa tatttgcgac
    52261 ttgatttgcc acaaagacta acacggagcc gaaaaaaatc agttttaaaa tcagactatg
    52321 ttcctttatc cattgcagca tcaagtatcg tttatttttc acattttccc attcctaact
    52381 tgtatacttt tgtgtcatac cccaatgtta tcttatttat tttaattttt ccactttaga
    52441 cctgttcttt gcttgcgatg atagaaaaag aaagatatcc taatgctaaa ggagaggata
    52501 acatgaaagt aggatttatc ggcacaggga atatggcaca agctattatt gatggtttat
    52561 taaaaaaagg aacagtctcg aaagaagagg tgttcgtttc cagtggacat tttgaaaatg
    52621 cacaaaaatt tgctgctgaa actggcgtcc atgcatgcaa aagtaatcag gaagttgcat
    52681 cacaatcaga tatcgttctt ttagccgtga aaccaaaaat cattgaaaaa gtattggaag
    52741 aactaagaga atatagccag aaagtcttat tcatttctat tgcttcagga aaatcattaa
    52801 tagatttaga aacagcgctt gaagatcctc aggcctccat cgtacgtgtg atgccgaatg
    52861 tcaatgtcag cgtaggagca ggcgtttctg cgatttgcaa aaatgaagct gccacggagg
    52921 aacagcttca gcaagctacg atgatttttg aagcaatcgg cagcgtctat cctttagcag
    52981 aatcagattt cagtacattc attggccttg ctggcagctc acccgcattc gtttacatgc
    53041 tgatcgatgc gatgggacgg actggtgtac tgaatggttt gtccaaacag acagccactg
    53101 agattgctgc aaaagcaatt atgggttctt gtcaaaaatt cctttcaagt gataaaaatc
    53161 catgggaact tgtagaccaa gtttcttctc ctggcggtac aactgttgca ggtgtagttg
    53221 ccttagaaga agcaggattc atcccagcaa tcatcaaagg aatcaatacg acgatcgaga
    53281 aagatcttga gatgttgaat aaaaaataat gatagcaatg ttttttcgtg ccttacaaaa
    53341 aaagaagagc tgtggctttt gccgcggctc ttcttttgta ttttttatta tttagcataa
    53401 tcagttgcac gagtttcccg aataacgatt actttgatgt gtccaggata atccagttct
    53461 tcttcgattc gtttacgaat atcacgtact aaacgaacag cgtctaaatc cgagatttct
    53521 tctggcttga ccattacccg aacttcgcgt ccagcttgaa ctgcgtaact tgattctaca
    53581 ccggcgaagc tgttcgaaat attttccaga cttcttaaac gacggatgta gttttctaat
    53641 gattcacttc gcgcaccagg tcttgctgct gagagcgcat ctgctgcagc tacaaggaca
    53701 gagataacag aagtagcttc cacatctcca tgatgagaag cgatcgcgtt gattactact
    53761 gggttttctt tgtacttggc agctaattcc gcaccgatct caacgtgaga tccttcaatc
    53821 tcatggtcaa gtgctttccc aatatcatgg agcaacccgg cacgttttgc taattggata
    53881 tcttcgccaa gctctgctgc taagatacca gctaattttg caacctcgac cgaatgcttc
    53941 aagacgtttt gtccataact agttctgaat cgcagacgtc cgatgatctt gattagatct
    54001 ggatgaagtg tatgagcacc gacttcaaac gctgcctctt ccccgtattc gcgaatacgt
    54061 tcatccattt ctttacgaga tttctcgacc atttcttcga tacgcgctgg atggattcgt
    54121 ccatcttgta tcagtttttc caaggtcatc cgtgcgattt ctcttcggat tggatcgaat
    54181 ccggaaagaa caactgcttc cggtgtatca tcgatgatta aatcgatacc agtcagcgtc
    54241 tcaagcgttc gaatattacg accttctcgt ccaatgatac gacctttcat ttcatcattc
    54301 ggaagggtaa cgactgaaac agtcgtttct gaaacttgat ctgctgcgca gcgttgaatc
    54361 gctaatgata ataagttttt cgctttgcga tctgcttctt ctttggcacg ctgttcagat
    54421 tcttttacca ttagagttaa ctcatgattc agctcttctt cagtcgattt catgatgaca
    54481 tctcgtgcgt cctcttttga taaaccagca attttttcta gttctttttg ttgatcttca
    54541 atcatttttt caacgtcttt ttctcgctct tcaattaatt gctgttttga actaagtgct
    54601 tcttctttac tttcaagtga gttctcgcgt ttttctaacg agtcatcttt acgattcagc
    54661 gtttgttcgc gttgaatcaa acgattctct tgagatttta attctaactt actttctctc
    54721 agctcacttt caacttcaga acggtatttc tgattttctt ccttagcttc taacaatgct
    54781 tcttttttta gagtttctgc ttcttttttt gcactatcga tgattccagc agctgatgat
    54841 tgtgcaccag ctatttcttt ctcgtgacgt gactttgcga ccataaaccc taaaccaaga
    54901 ccgacaatta aaccgatgat agcgaggaga atgttgaata ccataaaatc cacctccata
    54961 ctatcttttt catttttatc atctatacag cttctatgat aaattattct aaactcgtca
    55021 atatgcatct tcgcatatat gtgtacaaaa aacatgcaca actttattct aatgtttgta
    55081 ccccgtagtg tcaactttaa ataaacaaag aaacggcttt ctacttattc attaaacgat
    55141 ggtttttaaa ataaatgaca ctagtttcat ataggtaaac ctttaaattg agaaactttt
    55201 ctattaaatt attctttgta gatgaacaga tatttttatt ttatgtaccc actcgtataa
    55261 ttaaataact cacgatttct ttattcaata aaaaaacggc aggtcaagga gagtacctac
    55321 tcttcagacc agccgttttt gtttatcata atttttattc ttctactaaa ggcaattctt
    55381 cttgtccttt ttcatcttct gggacagcga cttcttcacc aataccataa gctgctctaa
    55441 ctagagcaga aacttctgcc atcatttcag gatgattagc catatagatt ttagcgtttt
    55501 cccgtccttg accaatccga tcttctttat aagaatacca agcaccgctt ttatcaacaa
    55561 tgtctttttc tactgccatg tctagaagtt ctccttcttg tgagatccct aaaccataca
    55621 tgacatctac ttcagcgatt ttgaaaggag gtgctacttt gttttttacg actttgatct
    55681 ttgtacggtt accaacaata tctgtacctt gtttcaattg ttctgcacga cgtacttcca
    55741 aacggatcgt tgcgtagaat ttcaatgcgc gtcctccagg agtgatttct ggattcccaa
    55801 acatcacgcc tactttttca cggatttggt tgatgaaaat agcgattgtt tttgttttgt
    55861 tgatcgaacc agagagttta cgcaatgctt gagacatcaa acgtgcttgt aacccgacat
    55921 gtgagtcacc catttcgccg tcgatttctg ctcgtggaac taaagcagca actgaatcga
    55981 ctactacgat atctacagcc ccacttgata ctaaagcatc agcgatctct agaccttgtt
    56041 ctcctgtgtc aggctgtgaa agaagtagtt catcgatatt cacacctaat ttttgtgcat
    56101 attgcggatc taacgcatgc tcagcatcaa tgaaagcggc cgttccgcca tttttttgta
    56161 cttctgcaat agcgtgtagt gcaactgttg ttttacctga actttcaggt ccatatactt
    56221 cgatgatacg tccacggggg taaccgccga cacctaaagc gacatctaac gcaagagagc
    56281 cacttggaat tgtagagatt tgttggtcga ttttttcgcc caatttcata atagagcctt
    56341 taccatagct cttttcaatt tttttcagtg cagcatctaa ggctgcttta cgatcatctg
    56401 ccaatacgat aatcctcctt atatttacaa atcagagcaa catttcatta tccttatcat
    56461 atctttttta gtgaaaaaaa gcaagaaaaa accgaacaaa tattcgcatt tatcattttc
    56521 ttaaaagctg ttttctcaaa agatcaaatc cttgcataac cgcattatat ctgatagcag
    56581 cacgatctct ggcaaagtga tatttttccg aaaccacgcc gtctttagat gaaatagcga
    56641 tccatactgt tcctgcagat tgaccttcta acgtgtccgg tccagccact ccggtgaaag
    56701 ctacactgta atctgttctt gctatctcac gtgcttgaat ggccatctgc tccacacatt
    56761 ctttgctgac tgttccatat tctgctaata gctccggatc aatctccaga aaaccagctt
    56821 ttgtttggag cgagtaggta acgaatccgc ctggaaatac ttcagataca ccagcaatgt
    56881 cgcctaatgc ggcttggaag gcgccggctg tcaaactttc cgctgctgtt acagtctgct
    56941 tgttttcttt cagtagttcc actacgactt ttgctagcga attatcatcg ccgtatccat
    57001 aaaaatattc ccctactcgt tcttggattt tttcttctaa tgctaaaaga gcttgattcc
    57061 ctgcctgaac atcatttgtt ttcactgtca gtcgtaatgt cacttcattt ggtttggcat
    57121 atggtgcgat cgttggattg atctgtgtct caatcagatc ttttagctca gtgaccagtc
    57181 gcgattcacc aatcccataa aagcgcaaaa ctttagaaat tagtttttct tcagaaggaa
    57241 aacgttcctc tagtaaagga cgtacttgtt ccacaaacat tggtttcaac tcattaggcg
    57301 gaccgggaag aaggatatac gcatgtgtat ctgtttgata aaaagtccct aaagcaagcc
    57361 ctgtacgatt tggtagagga accccgcctt cgataatctg ggactgttgc agattgtttt
    57421 tggtcatttt tcgatgggtt gtttcaaaat atgccaataa ttttttgtat ccttccgtat
    57481 tttgtatgag agacttaccg aggtgagccg cagttgcttc ttttgtcagg tcatcttctg
    57541 tcggtcccaa tccgccacat aagagtatga gttcacttct tgtttcagct agagcaatca
    57601 actcttctaa acgctgctga ttatctccta caactgtttg ataataaact tcgataccta
    57661 gatcagctag ctgttctgac aagaaagtgg cattcgtatt cacgacttgt cctagtaaaa
    57721 gttctgttcc gacagctatt atttctgctt tcattacttc ccgctccctt atatagtata
    57781 cgctgtattt ttatattttt ttatttaaaa agagggcaag gagctgtgac aaaaatcttg
    57841 tcacagctcc ttgttccaaa taaacagtgt tctcctgcca aaacctcggt cataagtcac
    57901 aatatacata aaacatgaaa agctgttttt tgaaattatc ccttgtgact cagagttaga
    57961 cggcaggctc acaacctctc cactaaacga tacttacatt gatcctttga acacaccgct
    58021 gtttttgatg aagtaatcca cacctgaata gatagtaaag atcagacaag cataaagcat
    58081 gatttgatct actggaatac cgatcaggct gaatgggata ttattgataa acagcaagat
    58141 aatagcaacc atttgtgtag ccgtcttgac ttttcccggc caagctgcag ccatgacttc
    58201 tccatgttcg acaagtagta aacgcaagcc tgtgacggct aattcacgac agacaatgat
    58261 cgctactacc caaccagggg cctttccttg gtcaaccaac atgataaaag cagtcataac
    58321 tagcatttta tctgccaacg ggtccgcaaa cttgccaaaa ttagtgacaa ggcctcgcgc
    58381 acgggcaatt tttccatcta accagtctgt gatactagct aaagcaaaaa taactgcacc
    58441 tactagctgt gtgacagcca gtgtggtgtc tcctacgtta aattgtcccc aatctaaagg
    58501 taaacctaca accaaaatga aaatcgggat catacaaatt ctaagtacag ttaatttatt
    58561 tggtaaattc acactatcga ctcctttctt ccctattcta cgtgactatc agcgaagttt
    58621 ccaccgatat tatttacttt tccaaatgaa tttattcaaa ggagtatttt tattgaaatt
    58681 gatctttttg aattaacgaa gaaggaccgc gacacagatt tgtcacgatc cttctttttt
    58741 atacctacaa gtaaacagat gcgtaaacta atttatacga tcattctgcg tattgaagag
    58801 taaggttcac attttttgga ctctgattgt tttcccctgg attaactggt acggattctc
    58861 cattcgcttt gatcgttgca ttgcttgctg caccaatcgt gatggtcgca tttgttgctg
    58921 tttccggtaa cacggtactc tgtgtttcat ttgctgccag tgtcccttga taaacatagg
    58981 cattgtctac tagcacacct aaccatacac gattgacagc agtaaattca agggttacag
    59041 gcttggtagc gtctgtgata tttactgcga tggcactgcc agaatcttct cctgtagcta
    59101 ttgccatttt cttttcttca cttgattttg ttgttgattc tactgtagaa gactctttgg
    59161 tctgcgtgct ttgctctgag gaagaggact cctcgactga tccttctact ttaagcgaag
    59221 aagctgtgtc tccgattatt ggatcagctt gacgatcttg ccaagtcata tagcccacga
    59281 caacgacaat cgccaaagca accaatccta ataaaatgac aggaagactt gtccaaaagc
    59341 gacttggatg cgattcttcc tgatgcattg cttttctaga agtacttact gtttcaggct
    59401 gcggacgttc agggaccgat cctgtcaatt tgcttttccc atcaaaaaca tcgactaaat
    59461 ggtctccatc ttctcctaca gcttcagcgt attgccgaat aaatgcccgc acgtaaaatt
    59521 taccaggcaa ttggtcaaaa tcatcattgt cgattgcttc caaataacgt ttttgaattt
    59581 ttgtaatctg ctgtaattca tctaaagata tttttttatt caggcgtgct tgccgtaatt
    59641 tttctccgat ggtttcaaaa gccactcgtt catcttctcc agtctgtttg attctccgaa
    59701 gcatctgctg ttgcaacgaa agacgttatg tttgggtgct gtgacaaaag tcatgtcaca
    59761 gctccttttt tccgaataaa cattgttctc ctgccaactc ctcggtcaca agtcacaata
    59821 tccaataaat ataagaagct gttttttgaa cttgttcctt gtgactcgga gttaaacggc
    59881 aggctcacga cctctttctt aaacggtgtt caatcagctg ttcctcggta ttagctcaaa
    59941 aaccggcaaa atataaggag atatttttcc gtatgtttct ctaatactca ggtcaaaacg
    60001 ctgatttcac aacctcttcc ttaaacggtg ttcaaaagct tgcatctgcg gtaataagtc
    60061 caaccaagtt aaaaacatta agaagctgtt tttacttggc tgttcttatt acttgatgca
    60121 gggcagcttt ttcacaacct cttggtacac ggtgttccag aagtagcttc ttcggcaata
    60181 agccgaaata tcacaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa
    60241 gctgaccact tctgtcacaa cctctttgat tacttcgttt gattttattt taatataagt
    60301 tgattaaaag agagcatgat ttgttttatt ttctcactaa tttttccaac acaactaaga
    60361 ataccataaa agctgatttt ggaggaggtt cctactacaa gtctaaaacg aaatttaaga
    60421 cttttcctca taaaatactg gtttattttg gtctcatgta aaactcgctg aaggcctctt
    60481 cacttataaa tgcttcccca gctgccagta cgtctttcat ttggatcgaa tcgatgattt
    60541 caggaagatc aaataaagtt cgatcgccaa ataaactttg cgtaaattga ttggcaatat
    60601 attcgatcga atttaatgat tggaaatatt gtccaagcat tttcttcttc agcaaatcga
    60661 gatttgtttc tgacacttcc ggatcatcag cgaatccaag aatgatttct ttgacttttt
    60721 ctgctgcttt ctctggttcg tccgtatctc cgctgaagtc cgcaaagtga aattcacgat
    60781 ccaagctgaa ttcaaaacca aagctgtcat cgataattcc ttgattgtac atcgctagat
    60841 agtttcgaga agtattgcct aaaatcattt ggaacaacag attgattgct gttttatagc
    60901 gtaacagttc tgttccttct tgcggcaatg tgtctaatcc tttaatacca agtacaaatt
    60961 tatctcgtgt aatggctgct tccaatgcac tttgtttgat gatttctttt gtgttttcag
    61021 ggaaataacg tacaatttct tgctttggag ggaaattttt tgcttcttgg ttttcccgaa
    61081 taagtttcat caatttctca ggctccatct taccaactac aaataaaacc atattgcttg
    61141 gctgataaaa cgtccgatag cacgtataca agtcttgagc tgtgattttg tcgatacttt
    61201 caaccgtgcc cgcaatatcg atatgcaatg ggtgtgtagg atacaagtta tttagtatgc
    61261 caaaaaacat ccgccagtta gggtcgtctt catacatttg gatttcctga ccgatgattc
    61321 ctttttcctt gtttacagtt tcttctgtga agtaaggtgc ttgtacaaaa tcgatcagag
    61381 tcgtcagatt cttttctacc tgatccgtcg tagaaaacag atagctggtt ttcgtaaaac
    61441 ttgtgaaagc attggcggaa gctccttgtt tcccaaataa ttgaaagaca tcaccatctt
    61501 ctttttcaaa caacttatgt tctaaaaaat gggcaattcc atctggaact ttcacctttt
    61561 ctttttcacc atagggaata aattcgttat cgatcgaacc ataattcgta ctgaacaaac
    61621 catatgtctt gtgatagtca tttttaggca acaaatacac ggtcaaaccg tttggcagta
    61681 cttcatgata aagtgtttca ttgatttgct catattctgt tttattcatt tgcatttcct
    61741 cctgctaaaa agaagattgc ctgcaattcg atttgctcag ctacttgttg tatctctttg
    61801 atcgttacgc tctccatacg tttcaaccat tcttcatcag ataattttgt ttccggcagc
    61861 cagctgtcca aaaaagaagc ttcgattgcc gcttgcggag agtctagaga aagcagatat
    61921 tggtttctca gcattgcttt tgtctgagac agttccaact ctgttatttc accatttcgc
    61981 aaactttcta attgctcgtg aatcagatga agtacttgat ttcggttctt ttcatcgata
    62041 ccggtttgga cactcatgaa tcctcggaac gtatccacgc tactagaggc ataataagct
    62101 agactttctt tctctctgac attcatgaaa agtttagagt gaggaaaacc gccaaataaa
    62161 ccgttaaaga ccattagcgc aaaacgttct ggttcatcgt aatacacatt tgtctgataa
    62221 gctaggttca gctttgcttg aacgattggc tcacgtactt gtcgttcctt cacgatattc
    62281 acttgaggtt gggtataaaa cagatctgga taaactgttt cccgcgactc aaatggtaat
    62341 tgcccaactg cttcagctgc tttgtccgga tcaacatcgc cgacaacaaa aatgtcgatt
    62401 tgatcatttg ccatcatttc ttgatagtag gacgctagcg aactagcagt gatcttgtcc
    62461 aaatcttcga ctacgcccaa ccctgggatc ttttgttccg ggctgttttc aaaataaagt
    62521 tcttgcaagg cataggaagc aaaagtttgt ttatcttcct tcaaactttc caaatataga
    62581 cgcagattgt tcttttccaa gtcaaacgtc aactgatcaa actgatgatt tttaatattt
    62641 ggataaaata aaacctcttt taaaaaatct accgcttgag aaaaaaggtt tggatcattg
    62701 acatattcac cattcacaaa actgatccct gcgtttagcc aatgtaaatt tccttttttt
    62761 ctaactgata atccaaagct tgcgccataa agctctgcaa gttgcgcact taactttgtc
    62821 tgatccgaat aattcaaact atttgtttcc aacatgctgc tgagaagtga acgtttcgtg
    62881 atgacttctt gttgcagacg cgcagtaaaa cggataaaaa tccggatcgt tttgtattgt
    62941 tttgttggta agacatgaag attcacgcct tctgccaatt gatacaccat atttatatgc
    63001 tccttttcac agttgattgc ccgcttactc ttttaatggg tcaacctgcc ttttttactt
    63061 attcctctgc ttgaaattta taagttcagg caattcgccg ttttttctaa atgatgttac
    63121 actttatagt atagcataga tgttttttat caaaagaaac agacggctaa aagcgtatat
    63181 tgttttttta ttttttattt ttcgatatac taaagacaaa taaaagaagg gagggtcatt
    63241 catgatcaaa gaattcaaag agttcatcat gcgtggagat gtcttggatc ttgctgtcgg
    63301 cgttgttatt ggtagtgcgt ttacaagcat cgtaaaccaa gtggtgcaag gcttgatcac
    63361 accactaata ggttggtttg tcgcaatgat cacaggtact tctgatttag aaggagcact
    63421 ttcaattctt gactggtcgc cgacaaaagg cgtcacattt gcgtttggta acgttattag
    63481 tgctatcatt acatttctga tcactggttt tgtcttattc ttagttgtca aagcggcaaa
    63541 ccgtgcgaag aatttacgct ccaaagaaga gcaagtggaa gtggaagaaa ctcctactgc
    63601 agaagattat cttagtgaca tacgcgatct tcttgccaaa caagtggcag aagacaatac
    63661 acatccagta gagcaaacaa atctttccga tacttctaaa taataaagaa tctaaaaaaa
    63721 agaaagccga ttttcagtgt cggctttctt tttttagatt cttaacttgc tacttgttcc
    63781 tttttcatgt cgatatgtgg aatatcatct tccaaataca catctgagat tgccttgaat
    63841 ccaaacgact cataaaaagc ttgtaggtat tcttgtgcgc cgatcacgat tggtttttct
    63901 ggaaaatttt tctggatcat gttaatcgtt tcttgaacaa tctttcttcc taaaccatct
    63961 ttacggttgt cctgatgaac aaggacacgt ccaaaatgga tactctccgc ttcttcatat
    64021 actcgcgtgt aggcaaggat cttcccatca gtatcttgaa aaaacgtatg ccaagcttct
    64081 ccatcaatgt catcaacttc ttgataagga cactgttgtt ccacaacaaa aactgcgatt
    64141 cgttctttga cgatcgcgta aaactctgct gttgacaatt cttcaaattt ctttacctga
    64201 tattccacta agcaaacgcc ccctgctttt ttattcttag cataccgatt cgcacacaaa
    64261 aaagcaaacg aaccttacga atctcaggct cgtttgcttt ttaaactgct tcagttaaaa
    64321 attcgatctc aactgtccga gtaagtacat ctgaatagct gtaagatact cgttcaaaag
    64381 aattttcttc aggatccaaa tcaacaacga atactgaagg ataggtttct gttaaaacgc
    64441 cgcggcgttc tgtttgacgc tttcttcctg tctgagcaac caacatgatt gggctgccga
    64501 tacgaccttc taaatctttc ttgattgaag ctaaagttgt tggcatacag ttcacctcta
    64561 ctatcaacta taccacatat ttttaaaatt ttcaagttta ccataaaaaa aaaagaaatg
    64621 caataaaaat aaataagaag ctcattaaga tttttctaaa ttattcctca ttataaaatt
    64681 tcaagtgttt ttttattttg agttttactc tcccgtaagc gctcattact tgcttgtgat
    64741 ccattgctaa acattcagcc atgtctacaa aatcaacgcc ttgcatataa taatgaaaaa
    64801 ttttagcttc tatttttgaa aactggattt cgcaattttc gattgcttct tttaataaaa
    64861 gatgctgaat tgctaaaggt tcttgcaatg tgatctctgc taaaaagtct ggtccttctg
    64921 tctctatttt ttggtcgatt gagacttcat ctttttgatc acgacgcttc agcgcgttct
    64981 gcttcctcaa cagagaatag atttgattgc ttataacgct tttataataa cttccaaagc
    65041 taacaccttt gcttttttcg taagttctca atgcctgata taaagcgatc cttgcttctt
    65101 gttcccaatc ctcagaaaca taatttctta aataataggt gtttttcaaa cgtagtaaaa
    65161 gtggaaaata tttttgatac agggcagcaa atgcttcttc gtcaccatta cgtgcagcgc
    65221 gcaataactc ctcagacata aaataattcc tccataaatt cgtttatgga ggaatcttat
    65281 catcaatgat tcatcgaact gattagaacg atatgttatt tattttttct cattaaatcg
    65341 tccaattttt gggacaattt ttttaactgc tcttcattcc atggagaatt acgtcggaaa
    65401 tcaataaaat gcatatcttt attttcttgg gctattgttt tttccgtttt ttttatcgtc
    65461 ttatataatt cataagcaga agttcgtaat gctccttggg aaaagatcat ccactgttct
    65521 gctaaatcgc ttgtcgccac tgtcacttgt gtcaaacggt cattcagctg accagcgatt
    65581 ctctcgatat aactgtcagc cgtttcgtct tctttcgtaa aaacaacatc caactggtat
    65641 ttcttataat tttgttggat gcccggaact agttgggcat cgaagacaac gatgacttcc
    65701 attccttcat atttcgcata atttgataaa cgatgtaaaa gagcttctct tgcatccgcc
    65761 attttgtcct gctttttaag ctggacaagt tccggccacg aaccaatcat gttgtagccg
    65821 tctacaatca acagctgttt tttcatggtc tactccccct gacgttggga aaaagcctga
    65881 tacataagca aaccagcagc aacactggca tttaagctct ggacgtgccc ggtcatcggg
    65941 atcgtcagca attcatccat ttcttttttc aatcctggac tcattccttt gccttcatta
    66001 ccaatgacta aagcaattga tcctttggca ttccattttt ggaagtttgt gccggtcata
    66061 tctgtgccaa atacccaaaa tcctgtttct ttgagctgtt gcacagcttg taccaaattc
    66121 gtcacgcgtg caacagggac atgttcgact gccccagtgg aagtctttgt tacgataggt
    66181 gtgattccaa ctgctcggtg ttttggtatg atcacaccat cgacgccact tgcgtctgct
    66241 gtccgtaaaa tcgacccaaa attgtgtgga tcttcgatgc tatccaaaat caaaaagaag
    66301 gggtcttctt ttttctcttt tgttcgttca atcagttggt caagggataa atattcataa
    66361 ggtgtaatcg caagaacgac tccttgatgc acgccgtgat cgctcaaagt ttctaatttt
    66421 tgtttaggaa cccatttgac tggcacagct tgttcacgtg cgatttcttt cagttcttct
    66481 actttttctc ctcgtgaatc ttcttgaaga aagagtttat tccctcgccc ttgttgtagc
    66541 gcttctactg cggcatggtg cccaaagacg aaattatctt ctaatgcttc ttcattttga
    66601 tcagaaactg actgatttcg tccagtttgc tttttatttg aatatctatt ttgttttttg
    66661 tcttcaaatc cacgtttcga ttgatgtttg tttgttcttt ctttacccat ttttttcacc
    66721 aactttctga atacaccagc ggatcaattc ttccatccgc tcggtttgtt ttgtcaaatg
    66781 cagatagccc atgagcgctt cgaaccctgt tgcgacccga tacgtcgtaa catcagcatt
    66841 ttttgcgctc gtatggcttt tagcatttct tcctctgcga taataaagtt cttcttcttc
    66901 tgtcaaaaga tgttcttcca gcatttgctg aatcaaaaag gcttgtgcat tcgcagaaac
    66961 ataattcgtt gccgcacgat gcagcttatt gggttttgtt tctccttgat caatcaggtg
    67021 gtcacgaaca tagatttcgt aaatcgcatc tccaacataa gccaaggcta aaccgttcaa
    67081 ttgtgtgtaa tctctcatgc ttctcttctc catcgggttc cttgcggtgt atcttctaat
    67141 aagatccctt tttctttcaa caaatcacga atttcgtcgc ttcggacaaa atcacgattg
    67201 cttcttgctt gatttcgttc ttcgatcaat tgttcaatct cttcatctaa taactcttct
    67261 gctgtaaata aaataccgaa gatcgaaagc cattgcgaga ataaagcttc tccttgtgcc
    67321 aagacagcgg cagaaacttt cggctggtct agataagtgt tcagccactt agcaagctca
    67381 tagaccactg tgatcccatt tgctgcatta aaatcatcgt ccatttcttc gatgaatcgc
    67441 tgttctaaat tttctaacaa agcgatttta tccgcatcat ctgccaaatt ctctgaggca
    67501 gtttcttggc ggaatttcaa attgtcaaac gtattcttca gtcgttgtaa attggtggct
    67561 gcttctttca tcgtcgtttc actgtagcgg atcggacgac ggtattgtgt ggtcgccatg
    67621 aagaaacgca agacttgtgg atcaacgttt ttgatcattt catgtacagt gatgaaattc
    67681 cctagagatt tactcatttt ttcatcgtct tcgccaatcg ttacatagcc attgtgcatc
    67741 cagtaattag cgaatttttt ccctgttttc gcttcacttt gtgcgatttc attttcatga
    67801 tgaggaaatt ctaaatcttg cccgccacca tggatatcga tcgtttctcc taaatgtttt
    67861 gttgccataa cggaacattc aatatgccaa ccgggacgtc ctttgcccca tggtgaatcc
    67921 caagaaatct cgccaggttt tgcttgtttc cataaagcga aatctaatgg gtcttctttt
    67981 tgctgctgtt cttcccctgt acgctgactt gctccgactt ccagttcatc gatggattgg
    68041 tcacttaatt tcccataatt ttcaaattta cgggtacggt aatacacatc acctgaagat
    68101 tcataagcat agcctttttc aaccaacact tgaataaatg ctaaaatatc tggcatatga
    68161 tccatgactc ttggatgcag tgtagcaggt tcgacattca acgctttcgt atcttcttca
    68221 aatgctcgga tgaaacgatc agcaacttct ggtgctgtaa tacctaattc gtttgctgta
    68281 cggatgattt tatcgtctac atccgtgaaa ttcgatacga aatcgacttt atagcctcga
    68341 tattcaaaat agcgtcgaat tgtatcgaaa gcaatggtgc tacgagcatt tccgatatgg
    68401 atataattat acacagtcgg tccgcagaca tacataccga catgtccctt ttgtataggg
    68461 atgaattctt ctttttttct ggtcaatgta ttgtagattt ttatcattct gatctcctca
    68521 ctttttctcc tttgattcga acgacttttg ctggtactcc taccgctgta gcgtcgtctg
    68581 gaacatcttt caacacaacg gcacctgcac cgattttggc gttttttccg atcgttaccg
    68641 gtcctaatat ctgcgcattc gcagagagca tggctccttg tttaacagtt gggtgtcttt
    68701 tacccgtttc ttttcctgtg ccgcctaatg ttacgccatg gaataaaatc acatcgtcct
    68761 cgatttctgc ggtttcgcca atgacgattc ccattccatg gtcgatgaac acgccagttc
    68821 caatcgttgc tcctggatgg atctcaacac cagttaggaa acgccagaat tgagcattga
    68881 tcttcgccaa taaaaagagc cggtgctgat ataaaaaatg agagaaacga tgccaaaaca
    68941 aggcatgaaa accagggtat gtcaaaacga tctcagctgt cgaacgtgca gccggatcgt
    69001 ttctctttgc tgcatcaatc gctcgggtaa accaactcat gactttccac tcctttcgta
    69061 agaattttat gtaggaaatc atcttcttat aaagaaaaga agcgcctttt aaataagttt
    69121 ccttatcaaa agacgctttc cgcgtggttc cacttttctt cataatcaat gattatctct
    69181 gacagctaac gcctgttata cgttcttggc tactttgttt cctataaaac agtttttcct
    69241 gttttctgtg tttcgccaag accactccca gaggcatttc ggcaaccatt cattgatacc
    69301 ttgcaccacc cggtatctct cttgtaatga tcagctgctt acttttttct gttcatcgtg
    69361 tttagttcag tacttgattt aaatgtgcta atgatttttc acgaccaagc aattcgatcg
    69421 tttcaggcaa ttctggacca tgcatttgtc ctgatacagc tacacggatt ggcatgaaaa
    69481 gattttttcc ttttacgcca gtttcttttt gaacagcttt gatggcagct ttgacagttg
    69541 gagcatctac tacttccatt tgttctagct gtgctttgaa tgcgtggaga acagtaggaa
    69601 ctgtttcacc agcaagtact tcttttgctg cttcattcaa tacaggatgt tcattgaaaa
    69661 atagcgtaga cagatcaacg atttctgcag catagctcat ttgaggttga tacaggctaa
    69721 cgatcttctt cacccattcg attgtctttt catctgggtt ttctgctaca cgtccatcag
    69781 cgattagata aggcagacac atgtcagtaa atgcatctag atccattgct ttgatgtaat
    69841 ggttgtttac ccattgcagt tttttcgcat cgaaagctgc gggtgattta cttaggcgtt
    69901 ttggatcgaa cattttgatc aattcttggt gttcgaagat ttcgtcttcg cccacaggtg
    69961 accagcccaa taatgcaata aagttgaaca ttgcatctgg tagatagcct aattcgcgat
    70021 attgttcgat aaattgcaag attgattcgt cacgtttgct tagtttttta cctgtttcac
    70081 tgttgatgat caatgtcata tgtccgaagg ttggtggtgt ccagccaaat gcttcataga
    70141 tcatcagttg ttttggtgta ttggcaatat ggtcatctcc acgtaaaacg tgagtgattt
    70201 tcatcaaatg atcatcgacc gcaacagcaa aattataagt tggcatacca tcgcgttttt
    70261 ggatgacaaa gtcgccaccg atattatcgg attcgaacga aatagcgcct ttcaccatat
    70321 ctgtaaatgc gtattctgta ttgcgaggca cacggaaacg tacaacagat tctagacctt
    70381 gtgcttcttt ttctgcttgt tcttcaggtg tcaagttcgc acatgttcct gcgtaatgag
    70441 gcatttctcc tcttgcgcgt tgtgcttccc gttctgcttc taattcttct tctgtgcaat
    70501 agcatttgta tgctcgattg ctagcaagca gctgatcaat cagcggttga tagatttctt
    70561 tacgttcaga ttgacggtaa gggccgtatt ctccaggatt ttcaggagat tcatcccaat
    70621 tcattcccaa ccaagcaagg ttttccaact ggcttttttc gccatcttcg atattacgtt
    70681 tttggtcagt atcctcaata cgaataataa agtctccatc attgtggcgg gcaaacaaat
    70741 aattgaataa tgcagttctt gcatttccaa tatgcaggtg cccagttgga cttggtgcat
    70801 agcgtacgcg tactttcgtc attttcttcc tcttctttca aactagactt tgactaacag
    70861 caaaaattcc gtcagttacg gcttctcaaa tatcatttat ttaaagccac tcagcacaaa
    70921 ttttaccttt tctaaggtaa atagtaaagc caactggttg aatttcctta ccagttggct
    70981 gaatttcttt tttattttga ttgtttagtc tttttctctg tctctttttt attgtcgatt
    71041 cctcgtcctg catgtgcagg tttagcaaag atcatgcgtc cagcagctgt ttgaagggca
    71101 cttgttacaa cgacttcgat acgttcattc atgtaatgct gtccatcttc tacgacaacc
    71161 atcgtgccgt catcaaggta ggctactcct tgttggcgtt ctgtcccggc ttttactact
    71221 agaacattca tcgtttcacc agggatgacg actggtttta cggcatttgc caacgcattg
    71281 atattaagaa caggtacatt ttggaattca gagactttat tcaagttata gtcattggtt
    71341 acaatgacac catctaaaag cttagccaat ttgatcaatt tgctgtctac ttcactgata
    71401 tcttcaaagt ctccatcgta catttcgaca gatataccct cttctttttg caaggcattt
    71461 aggatatcta atccgcgacg accacgcaca cgtttcaaac tatcccctga gtccgcgatg
    71521 tattgtagtt cgtaaagaac aaaattaggg atcatcaagg ttccttctaa gaatccagtc
    71581 tttgtaatat cataaatccg accgtcaatg atcacgcttg tatccaagat tttatattta
    71641 tggaaatttt ctcctgattt tcgttctaac agttgactct caacttgact agctgtttct
    71701 tgctcgattt ttttgcttcg tgaaccaaaa actttcttcc attcttcgat tcgtgtcgtt
    71761 cccattctca atcccagata gcctaagatg atcatcagta aaatcggcaa tacactattg
    71821 acgaatggaa tttccatatt gtaaagaggg gtcgagatca caacacctaa agtcaatccg
    71881 atgatcgcac cgatcgcacc gaagagaaga taagtcaagc tgacctcact tagtttttgt
    71941 tctacttgtt tgataatagc tgagatatgt ttggccaaca gcaaagataa taaaaagaaa
    72001 ataagtgcgc ctaacaggct gttggtaaat gtattattca gccatccgtt tgactgttga
    72061 ccgattgcct gccaagctga gggtaaaaat gaaataccca agcttgcgcc gacaatgatc
    72121 atcagcaaag taatgacacg tttttgcatc gtttttcctc cgtttcgaca atcatttatt
    72181 agttagcgga acacacgctt caacgtttca gccaaagttg ctactccaac tatctcgatt
    72241 ccttttggcg cttcccagtt acctaagttg tttttaggta ggtatacttt tgtgaagccg
    72301 agtttttgga cttctttgac tcgttgttca atatgactga cacgtctgat ttctccagtc
    72361 agtccaattt caccgatgaa acattccgtt ggctgtgttc ctttttcttt atagcttgaa
    72421 gcaatactga cagcgatagc taaatcaatc gctggttcat ttaattttac cccacctgca
    72481 gcttttaagt aagcatcttg attctgaaga agcaacccag ctcttttttc cagcactgcc
    72541 atgatcagag atacccgatt gaaatcaaga cctgttgttg ttcgtttggc atttccgaac
    72601 atagtaggtg tgactaatgc ttggatctct accaaaattg gacgtgtccc ttccattgcc
    72661 acaacgatag cagagccagt tgcaccgtct aggcgttctt ctaagaaaat ctgtgaagga
    72721 ttagcgactt cttccaatcc atgctcatgc atttcaaaaa tcccaatctc attcgttgag
    72781 ccaaatcggt tttttactgc tcgcaaaatc cgaaaactat gatgttgttc accttcaaaa
    72841 tataacaccg tatccaccat atgttctaac attcttgggc cggcgatcga gccttctttg
    72901 gtaacatgac cgacgataaa aatggctatc ccatttgttt tagcggtttt gagtagttct
    72961 gcagtggttt ctcttacttg gctgacactt cctgccacac ttgtgatgtc tggctgcgtc
    73021 atcgtttgga tggaatcaat gataacataa tcaggggaga tatgttcgat ggcacgactg
    73081 atttcgttca tatctgtttc agcgtataga taaaattctg tgttgatact tccgaggcgt
    73141 tccgcgcgta attttatctg ctctgcgctt tcttcgccgg atacatataa gacttttccg
    73201 cctatggctg ctaattgctg agaaacttgt aacagcaaag tggatttccc gatacctgga
    73261 tcgccaccaa tcaagaccat agaccctggc accacacctc cgcctaacac acggttcagt
    73321 tcttctaatt ttgttttgat ccgaggttct tttttaggga cgacgtctgc gatttttgtt
    73381 ggttttgctt tttctcctgt caaacttgtc cgagttctgc ggtccgttgt atcttgttcg
    73441 atttcttcga ccatcgtatt ccattttccg caatttgggc agcgtcccaa gaacttaggc
    73501 gacacatacc cgcaattttg gcaaacaaat tgtacttttg atttttttgc cattgtaccg
    73561 cctcctttta tcctaatcat gagacattaa atcaagctta agtatcttta acgttttatt
    73621 tactggaaga accaaatccg ccttgacgtt gagcagtcgt ttgatcttga tctgctttta
    73681 aaaacggcaa aaagatccct tggccgatac gctcgccttt tttgatcact acatccttga
    73741 aaccaaagtt ggtgaattgg aacatgatat ggccttcatt tgcctcatta ttgtaataat
    73801 cactgtcaat cacacctact ccgtttgtca acactaaaaa ccgcttcaac ggattgcttg
    73861 aacggttagc aagctgcaaa aattcatctt ctcccatgta agctttgatt ccagtaggca
    73921 cgagggttgg tttcaattgt ttttcatttt ctgatacatc ttttttcaat ccatctgcga
    73981 ctgtttccaa cccctttttc cagcctgctt tccagatact tggaatcacg acctcttctg
    74041 ctgcttcaaa atcatagcca gcagcatgat gtgtagcgcg ctgcggtaga ttgatatttt
    74101 gatctttata tttagaaata acttcaaatc ctctttttct caccggtttt cctccctaaa
    74161 taaactactc ctattctaac atatccgagg ctgtaaaaga ctttctttac aaattcttca
    74221 agaaattctg ctatcttaaa gtaaaccatt aattcgttct ttttccaaac gactgcaagt
    74281 tgtacaaaaa aactattttt tacatgactt tactcgtcaa aacaagtaga atagaacgaa
    74341 attaatgagt ggatatttga ttgaggtgtc acatgcgtaa agaaattaaa aatgcaaaac
    74401 gaattattgt caaagtagga acaagtacat tgatttatcc caatggaaat atcaatcttg
    74461 cggcaatcga tcagttagct tttgtccttt ctgatcttag aaatcgggga aaggaagtga
    74521 tcttagtctc atcaggagct gtaggcgttg gtatgcataa attacatttg tcagaacgtc
    74581 cgactttgat tcctgaacag caagctgcgg cggctgttgg tcaagccgaa ctgatgaata
    74641 tctataatca aagattcagt gtatataatc aacagacggc acagatcctc gtgacaagag
    74701 acgtggtaga ttatcctgaa agtcgtaaaa atgtgaggaa tacattggaa cagcttttga
    74761 ttatggacac gatccctatc gtgaacgaaa acgatactgt agcagtggat gaattagatc
    74821 atctgacaaa atttggcgat aatgatcagc tgtcagccat catggcaaaa cttgtcgcgg
    74881 cagacctttt gatcgtcctt tctgatatcg acgggtttta ttcagataat ccgactacaa
    74941 atcccgaggc tcagatgtat cgctatatcg ataaaatcga tgaaaagatt ctggcacaag
    75001 caggtggtgc tggtagcaca tttggaacag gcggtatgca gagtaaatta aaagccgctt
    75061 ctaggatatt tgaagcaaac agcgcaatga ttttagcaaa tggaaaaaat ccggcaatta
    75121 tttttgatat tcttgcagga aaagaagtag gtactttatt taaggaggac ttgaaatgac
    75181 tgacttgatg caattaggac aacaggcaaa agatagcgcg caacaactag cacttatgcc
    75241 tacaaaccgc aaaaatgagc tacttgttca aatggcacaa accatcaaaa agaatcaaca
    75301 agcgatcatt gaagcaaatc ataaagactt agaaaaagca gtcgaaaaca atatcagtga
    75361 aacgatgcaa gaccgcttgc agctgacacc tgagcgaatc aatgccatgg ctacagagat
    75421 cgaaaaaatt gcttcgttag acgatcctat tggaaaagta gatgagatgt ggacgaacac
    75481 cgacggattg agaatcggca aaaagcgcgt gccactaggc gtgatcggca tcatttacga
    75541 atctcgtcca aatgtcacga cagatgcagc tagtctagca ttcaaatcag ggaatgccgt
    75601 tatccttcgc ggtggcaaag aagcattctt ctcgaatcaa ttattagtcc aattattgca
    75661 gcaagtactg gtcagtgctg gcgaatctcc ttatgccatc cagtttgtcg atgatacttc
    75721 tcatgaaact gcaggacagt tgatgcgatt gacagaatac ttagatgtgc tgattcctcg
    75781 aggcggagca aaattaatcc aacgagtcaa agaacaggca acggtaccta tcattgaaac
    75841 aggtacagga aataatcacg tatatatcga taaagaagca cagttatcta tggcagtgaa
    75901 catcatcgtc aatgcaaaag cttcccgtcc atctgtctgt aacgcggcag aaacattgct
    75961 gatccattct gagatcgcac cttttttctt gccagctatt gaaaaagaac tggtagaaca
    76021 cggggtctct ttacgtgcgg atgctcgtgc gttagaatat ctagagacgg ctgctttagc
    76081 agaagacaca gattgggata ctgaatatct agattatatc cttgctgtca aagtggtcga
    76141 ttctttggat gaagcaattg cacatatcaa tcggcataat actaaacatt cagaaacgat
    76201 cgtgacagat agttatgcgg ctagtcaacg tttcttaaat gaagtggacg cggcggctgt
    76261 ctatgtcaat gcctccactc gttttacaga cggatcggta tttggttttg gtgcagagat
    76321 tggtatctct actcaaaagt tgcatgcccg tggtccaatg gggttaaatg aattaacttc
    76381 cacaaaatat atcatttatg gcgatggaca aatccgcgaa taatgtttcg tgtgaaacat
    76441 tattcccgcc ttttgccttt tttctgtaaa ggttctatcc aactagaaag gtgtcaatat
    76501 gtttgaaatt ttaatgattt tttttattta ccttatttct ctgaatatcg ctgcttttct
    76561 gggagtcggt attttatccc ttttctttca attcaaaaaa cgaagcatag ggagtcaacg
    76621 ggaaaaatgg tcgcagtatt ttgacaaaat cgggcaaaaa gggctggtta cacgcttgca
    76681 cattagttac atggttgcat tatgcttatt agcgacaatc aattactatt cttttttcga
    76741 tcattcaatc gcttatacga ttacgctact gattgctggg atttttcact tatcttataa
    76801 atatcagctg aataaaaacc acttgaatcg gactttccgc taaaaaatat ccgtacgata
    76861 agtagagtgc cttgaagatc ggcaaaaaac tgccggactt tttagaggct gtgacaaaga
    76921 ttttgtcaca gcctcttttt ccatataaac ggcgttcgcc taccagctgc ctggtaaatc
    76981 tgtttcctct tcgttaagaa gcgaaaatcc gtcaaatgtt tcgccatcat aataacgaag
    77041 cagctcatcc atggacaagt tcatcgtttt ttctttttct tcttccgctg attcagccag
    77101 tagctgttcc cgatacacct gatacatacc agctattttt tgctgcatcg cttttctagt
    77161 ttcaccttcc gcattgatta ttggcaattc tttgatatag ccacgataaa tcaaccgatc
    77221 atctgaaaat tcaatgggta attcaacgag tgtcaacccg acttcctgaa aatattcttc
    77281 cagcatctat tatcccccca ttctttttct taaatgaatt ttagcttacc tactgaaaat
    77341 tttccagttt cattattttg agaaaaaaag ggaatgtgac aaaaatcgtg tcacatcccc
    77401 tttttccgaa taaatggtgt tcttctgcca actcctcaat cataagtcac aatattcaac
    77461 aaacatgaga aactgttttt tgaaattgtt ccttgtgatt cagagttaaa cgacagtctc
    77521 acaacctctt ggtaaacggc gttcaatcag ctgaccctcg gtattagctc aaaaaacggt
    77581 aaaatatgag aagctatttt tccgttttgt ttctctaata cttaggataa aacgctgatt
    77641 ttacaacctc tgttaaacgg tgttcaatca gctgtccttc ggtattagct caaaaaacgg
    77701 caaaatatga ggaactattt ttccgtttgt ttctctaata ctcaggacaa aacgctgatt
    77761 ttacaacctc ctgataaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaaccaa
    77821 acgaaaaata tgagaagcta tttttgtttg gctgttctta tgacttgatg caggacagct
    77881 ttttcacaac ctctgatttc ttattcttct tcatttgtag caaaataatt acggtgataa
    77941 atgatacaac atacactgat aagaacaatg gcacctgcaa aataaaacgc atagctttca
    78001 ccaatatgtt caccaatcac acctgcaata aatggtgcta aagctccacc gaaaaagcgg
    78061 acaaaactat agctggacga agcaacgttt cgttgcagac ctggtatttc catagcaatc
    78121 gtcgtcaaca gtgtattgat aattccttgg aaaaatcctg ctaacacaat gctgatcggt
    78181 acaaggactg gcatagaagt tccagctcct aataacagca aacaaataat gaataagaca
    78241 aatgctgcta aaattgtccg ataagtcgta aacttccgct caagagccgg tgcaacgaaa
    78301 atcgaagcaa tagccagaag cacaccccag ccaaaaaata caaaaccgac ttctaattca
    78361 gaatagccaa tcaataaaaa tggcgcatac gcaagtaaag taaagaatcc gaaattatat
    78421 aacaatgcga ttagtccaac tgaacgaagt ttatgattgc ttaacgcttt gacaccttcc
    78481 caaaggccta cttttctctt tggtttctca gtttcaggta aaagtaccgc tagggctata
    78541 aaaccgcaaa acatcaaaaa tgctacccca aaaaatggat aacgccatga accactgccc
    78601 aagaccccac cgactagagg gccaacagcc attccgcagc caagtgctgc ttcatacatc
    78661 atgattgctt tttctgtgtt accaactaaa atactgacga tcgttgctaa agcagtagag
    78721 acaaataaag cattcccgac accccagccg gcacgtaacc caatcagcat tccgatattc
    78781 ccagataatc cgccaagacc agcgaataca acgatgataa acaatcctgt catcaatgtt
    78841 tttttcaaac cgatccgact agataagaaa cctgtaaata gcatcaccac accagtgact
    78901 aacatgtaac tagtaaataa cagggtcgtt tcagctggcg tagcgtttaa ctgtgcagca
    78961 atcgttttta agattgggtc tactagaccc actcccataa aagcgatcat acaggtagct
    79021 gctacaacta gcgctgaact tttccccttt gtttcttcat ttgtttgttc ttgtatatct
    79081 atttgattct ccaatatttc catccctttc tctctattag catcatacat gatttatttt
    79141 acatgtcaat atgcacatgt aaaacgtgga aactttactg tgatataata aagaaaataa
    79201 gacgagaggt aggattttta tgaatacttt agcctatata ttattatgcg tgcttttatc
    79261 caaaccacgt tctgggtatg aattgaagca gctgatcaca attttttggg aagcccatca
    79321 cagtcagatc tatacaacgc ttgccaagtt agaccagcag ggttatgtga ccgttttgga
    79381 caaagacgag cactctcaaa aaaagatcta ccacttgact gatgaaggac gtgctcttgt
    79441 agaggaatgg atcaaagagg aaactcccgc tcctacgcaa aaagatgaat ttctagcaaa
    79501 aatctatgct ttttcgacgc tcgataaaac aacagctact ggactgctat tcactagaga
    79561 acaacagctg aacaaaatca tgcaaaaaaa tcaaaaaaaa ttgaatgacc tctcgctaga
    79621 caagaaacaa gaatttggac gttatgttgt gatccagcgc agaattatgc tttgtcagca
    79681 ggaactccaa tggtgtcagc aagtaagaga acaaatgcag cagttttttg agtaagggat
    79741 aaacagaacc tttctagaaa tatctattga agagcaaatt atcttcaata aaagagcaat
    79801 acagttggaa aagaaaaagc gatccgaacg acaggccaaa acctatcgtt cggatcacta
    79861 tttttctaga actgcattca agagactatg acaaaaagca tgccaaggcc ttttttcaaa
    79921 taacagtgtt ccatcattca ttactttgaa ttgcttttag cacacttctt gaaagcgggc
    79981 caacgatgat caactgcaac ggtaaagcgg caatcacatt cattttccaa gcattcatat
    80041 aagcagagaa taattgatca ggtattcctt gttccatgat cacaccgaat aaagacatac
    80101 atgtcaccat tcctaaaacc atcaagcatg aaatagttaa gatcatttgg accttgcttt
    80161 ctggatttac tggtagttta aaggcaattt ttttcgccag cacaccgatg atgaagacat
    80221 ccaaaatgaa agccaccacg aatccaggca ctagaccaat caacaaactt gataaatgaa
    80281 gatcttgatg cagccataaa ttatacgcgc tcatccccaa gaccatcaaa aaacacatca
    80341 ttgttgtaaa aattattcct tcttttttat ttgtaggcaa tctgtaccac tcctttaaat
    80401 ttgtcacgaa aatcatcgta gcacatttaa aaatttctcg taagtacttt ttttattttc
    80461 tgccctttta tttcataaac ttcatcagcc gtacgctcga caaagtaaga atcatgagaa
    80521 gtaaacaaaa tcgttcccgg atatatttgc attagcttct ctaaagcttc gatcgttgcc
    80581 atatcaataa aattagtcgg ttcatctaac agcaacacat tacttggctt agtaaaaagc
    80641 aaagcaatcg tcagacgggt cgcttctccc ccacttaatg tacataacgg tttcgtcaaa
    80701 gtttcctgag caaaccctaa gtgattcagc aaactacgga caagcgattc tgaaaactct
    80761 gtttgtctca tgacaaaacg aatgatggat tcttcagatg tcatttgata acccttttgc
    80821 tgatatactt gaaagcttac tttcggagag agaaggattc cttctccttg tttgcggata
    80881 tgttctaata aggttgtctt acctgaacca ttttcaccga caatcgcgat ttttttacct
    80941 aaagaaaact gaaaatcacc atttaccagt aatgttctcc cacttctttc caattggaca
    81001 ttttgtccca tgatgggata gcggctgtgg agttcaagag attttggtac tggaaaacgg
    81061 atttgtttca tctgctgcgg cttggttgtt tctcctattt tttggagtct tctctctaat
    81121 gttttcgcat tcttttggat ggctttttgt acactgtctt tttgtttaga ggaagacaac
    81181 cgatccagtc tgatttgttg ctttttcttt ttactggaca ctttttccaa cttttccgct
    81241 tgttttttct tttcttggat cgatttttcc aatcgttttt tctctttcat gatcgactct
    81301 gcttctcgta gctgagtctt tttctccaat tccttttgag tgagataggc actataattc
    81361 cccgaaaact ctcggatttc tccgtctttt acttcccaga ttttcgatgc tagctcatct
    81421 agaaaatagc gatcatgact aacaaaaacc agcgtaccat aataataacg aagctcttca
    81481 atcagtcgat caatactttt tctatctaga tgggttgttg gctcgtctag aagcatccct
    81541 tgttcataag aagaaagaag acgtatcaac tcgatctttc gttcttcccc tccgctccat
    81601 ttccgctctg aagtttcttc cagtcttaac tggaaatgac tggctaattc caaatttagg
    81661 tcctttgctt cagcgagata ggttaattga ggcaggtagt tgaaggtgat ctctgtttgg
    81721 attttcccat gatcgggaaa aagttcaccg gctattagtt tgagcaaagt cgatttaccg
    81781 acaccatttt ctcctatgat ccctatacga tcttgctgat agacacgaag agaatcaata
    81841 gatagttcta gctggttgcc aaagctgact tgtagatttg ttatatttac tgctaaattt
    81901 tccatatgtt ttacactcct atttcatgta aaacaacaat tatcgatact aaaaaagagc
    81961 agaaaaatct gtttgcaaaa aaactgcatc acatcttttc ctactctgaa cgaaataact
    82021 atgactaaat caccaaatct gtcatagctt tcacctattc tactgtcgtt cgaaaaaatg
    82081 gacatactcc atccatgaaa ttgttgttta tacatgtctt ttgaatttat ttagttgtta
    82141 ttcaaaagtt cgaaacgtaa tttcatcgat gcagtcattt ttccgacctc cttttttatt
    82201 aggttaccac acacgattca aaaaaagcaa tagctactga atagtaactg aaaacctttt
    82261 attcgaacat agtgatcttt tctggtgcta aacgaacaga ctcgtaacct tcttctaccg
    82321 cttttcctat tgataaaata ataactggaa cataacggtc tttatccaaa ccaaatgcct
    82381 ctgccaactg atctgcttcg aatccaccaa ttggatttgt ttcatagcca tgatcacgcg
    82441 caactaacat gaattgcata gccgctaagc tagaatcgac tttgactaca tcgttcattt
    82501 cttctcttga aaaactcttg taataaggaa tgatcgcagc taattgttga tctctgactt
    82561 cttttggcat cttccctgat tcgtaagctt ggttgtagat ttcttcgcca tattcgtaac
    82621 attgcatatc gccaaaaatc atgaccattg cagaagaagt atcattttgt ctcgtattga
    82681 aacggatcaa aggacgcaag atttcttttg cttcctcgct ttcagcgacc acaaagcgcc
    82741 atggtttcat attgacagaa gaaggtgcag tcgtcgcttc tttgatcatt tccagcattt
    82801 cttcgtgtgg gattttgtat gtttcatcat atacgcgaac ggatcttcta ccagtcataa
    82861 ttgttgaaaa atcatttttt tgttccatta ttattaacct ctttcgtttc tgttgttata
    82921 ttgcaaagtt gggtattcaa tttatctaaa agtgttagaa attgtttcat ttctacatcg
    82981 ctgaaagccg gggatagcac ggaacctgta tctttatggt ccatttcaca atgcttgatt
    83041 ttcttctggg ctttttctgt tagcgctaca tacacttccc ggttgttctg aggatttctc
    83101 tgacgcgaaa catagccatt tgcttccaat accttcagat gacgagtaac tgctccttga
    83161 tcaatctgca acttttcttg caaactgctt tgtagcaatg gattttcttc tttcagtctc
    83221 atcatgatct cgtatctagt aagacttata ccgatatttt cttcaaagat ctggacgatt
    83281 ttttgatcgg ctaatttgat ttgatataaa aggtgactaa tctcttctaa agacataatt
    83341 tcctcctttc taataattga ctcgtcaacg attgacttgt caataataga ataaaaaaag
    83401 aaaaaagtca aagaatcagc tgtgtaataa aaaaaacgct ctcaatagaa aagtatagag
    83461 aaaagaaatt ttttgtagaa tgaacggaaa aaatgataaa gaaagcacaa cgctaaaacc
    83521 aagattattg attcttatca aactatagaa gatagctctt ctgcagtaga taattttaca
    83581 ccgccaaaaa tttccgaaat cgccttttgc aagaatcccg tcgaatatta gaaattggat
    83641 cagtatgctt aaacagtaat aaaaaagtta tgacaagatg ttgtcacaac cttttttgag
    83701 taaacggtgt tcaaaaactt gcatctgcgg taataagttc aaccaaacaa aaaacatgaa
    83761 aatctgtttt tgtttggctg ttcttactac ttgatgcagg gcagcttttt cactacctct
    83821 ttttaataac cataaaatcc tattccttca tatctccagc ccatcggtgt tagccaatct
    83881 ctttccttag cactcaaggt atagtgatgg gtaccagttt tttcatttgg attaaatagt
    83941 cgataaattg gcttggaacc accagaataa aaacttagac cttcataacg ccaaccgatt
    84001 tttgttaaag agttgatctc agattgtgcc attgtgtaat gatggtctcc actgtaagga
    84061 ttgtataaac ggtagacagg ttgtccgctg tttggtgctt gccaagcaat cccttcatat
    84121 tcccagccta cagttggcag ataatttttt tctccggcat tcaatgtata taaatgttct
    84181 cctgtatgac ggttatacag acgatacatc ggagaagttg aagttggtgc tgtatcatac
    84241 tgtgtcagat tataggtttc gattacattg ttcaatgtag aaccataatt aggcgcagtg
    84301 gcataacgac ctgttagcca agccgtagca tctttgtaag agttcgtatt gcttttccat
    84361 gcaccggaat agtagtaaac gcctggctga aaagaagtcg tcttcaatac cgttacgtta
    84421 tcttgcaatg attctttgta cgaaggatat tttctaaaag cggcattcac cgtaatccat
    84481 tgcccattca catattccga agtaggcatc gtaacagatt ggccattata gcttccttta
    84541 atcccaaata gattgtaatt aggggcagaa gccaaagtac tgttccccca gccactttca
    84601 acgatggctt gagcaatcat gactgatgca tataagtcat tggcacttgc caaactttgt
    84661 gcagttgagg caatactatc aatgaacgct tgttgagaat tagcagatga gcgagcataa
    84721 aaagcatagc cagtatagtt ttcgaattca gacaaatctg cttgatgggt atgtgtcaat
    84781 gtttgcccat ctgtcaattg gttcgtgatt tcttctgcat tctctggatt gttctgagct
    84841 tctgctgatg tactgtcttc ggtttgtgtt tgttctgttg tttcagttgt tggttcttcg
    84901 gttgaaattg tattttctga gacagtagct gactgcaaag tactttctgt atcgttttca
    84961 attcctgttt ctgaagaact cgatgtctga gttgcgacag tttctgtcga ttcttcagct
    85021 agcactgttg tgttggcaac tgctagattt cctaaaagaa taacgctaaa taataaattc
    85081 tttgctttca tcttttttct cctttgaatt atgaaacttt tcctaaataa cagtgtaact
    85141 aaaaaagtaa aagcaagtca atgtccatat ttaaataaca tttgtttctt tttaataaat
    85201 ttgctttttc tgcataaaaa gacgtaaatg aagaatattc ttctccattc acgccttaaa
    85261 ttgatggtcg tttgaataac tatttaacaa gtaattctct ctggatatta tccgttatgg
    85321 attatacttc ctgtgtcgtc ggacggataa tcatgttgct gacagacatc cggtctggcg
    85381 tttctatcgc aaatgctaca gcagaagcta tatcttcaga tgttaatccc cattcttttt
    85441 gcgcttcatg aagttcaaga gcagcctttt tgtcgctgat ggtttgatat aattcagttt
    85501 gaacagctcc tggagagatg atcgtagatt tgatgttatt ttgccgttgc tcttgacgta
    85561 atccttccat gattgcacgg acagcaaatt ttgttccgca ataaacggcg gaatcaggat
    85621 aaacaacatg tcccgccaca gaatcagttg aaatgatatg cccagatttt tgtttttcca
    85681 tgattggaag tacggcggaa attccattta acacacccat gatgttgata tcaagcatat
    85741 tttgccattc atcacggtga ccttcaacta atggagcggt tggcatgatt cctgcattat
    85801 tgtacaatac atcgattcga ccgaactttt ccatcgctaa atcgataact gcttggactt
    85861 gtgcaaaatc tcttacatct gctgtttgaa tatatagctc agcttctggt aaagattctt
    85921 ttattgcttt taggcgatct tctcggcgtg cagctataac tagtttagcc cctttttctg
    85981 ctaatagctt cgttgttgct tcaccgattc cgcttgaagc gcccatgatg acaatcactt
    86041 tttctgataa atcattcatt ctattctcct cctgttttga aaaatctctt gcttatactc
    86101 actatctctt atttcatctt actgttcaaa taatccgttc gacaggtttg acgattttgg
    86161 cagggattcc tgcaacgatg gtattgtctg ggacatcttt cgtaacagtt gcattcgctg
    86221 caacaatggc attctcgcca atcgttacgc ctggcagaat agttgctcct gctccgatcc
    86281 aagcattttt cttgatgtgg attggcttta ctgacaagcc tcttcgttct tttggatcgg
    86341 ttagatggtt caccgtgatg aggttgacac gaggaccaat caatactgaa tcttctaaac
    86401 agatgccacc taagtcaacg aacatcactt gacgattgat aaagacattt ttccctatac
    86461 taatatgttt gccgaaatct gtataaaaag gcagcagaac agtcaccgta tcatctactt
    86521 tgtcactaat gatattttct agccgtttgc ggatatctgc tggttcatgg tacccagtat
    86581 tcagcgctgc taaaggctct tcgttttccg cttggatctg atggatcact tcaaagagcg
    86641 gatccgttac tcgaatctct ttattgacga tttgtttttc gatgaggctt gtcattttgc
    86701 tccctccttt tatccttact ttataacgga cggcttatga tgtctaatac ttataaaaca
    86761 tacttaacta ttccttttaa ctatacttag tggtatgctt ttttaaaaac aggagggaaa
    86821 aaatggatat tcgtatactg acgtattttt tagcagtagc tagagaaaaa aatatcagcc
    86881 gagcagcaaa atctctgcat atcacgcaac ctactctctc aaaacaactg aaagatttag
    86941 aagaagaact tggtgtgaca cttttcactc gaggctcccg agagatacag ttgacggatt
    87001 ctggtcgata tctttattca aaaggaaaag aaatcttgtc gttggtagaa aaaacggcga
    87061 acaatttaac aaatgacgca atcatctctg gagaaatcta cattggcgga ggcgaaacta
    87121 aagcaatctc tttcatttct gatagccttc attcgttgat caaggcgcat cctgatatcc
    87181 agtttcattt atatagcggg aatgcagatg atatcataga caaactggat agcggattac
    87241 ttgattttgg actcgtaatc gaaccgacaa acaaacaaaa ataccagtca tttcgactgc
    87301 cagcccaaga tcgttgggga cttttgatac atcggaatca tcctttagca aagcaaacag
    87361 tcatccatcc gcaggaactg aaaactgttc ctttgatcat ttcccggcaa acgtcagtgg
    87421 acagtcaact agctgaatgg ctaggtttca gcatagatca gttatcgatc gtcggaacat
    87481 ataacttatt gtacaatgct tctttgatgg tcgataacgg gacttttggt gcattagctc
    87541 tagatgggat catcaatact tatgggacgg aaaaagtatt catcccactc gatccgccat
    87601 tacaagcttc actgaatctc atttggaaaa aagaccagcc tctttctcct gctgctcgta
    87661 aatttttaga tgtcctaacg gagaaataca gttaagtaga gtttttttcc ttcgctttca
    87721 gctttttaac aacgaataag ttaagcaaaa gatccaatga ttaaataaca taagtttctt
    87781 aatttgttcc ttccttttat ttctgataat tccagtaaat tactataatt ataaaaaaag
    87841 aattgacaaa acataactgt ctatataaaa ttgattacgt taacaataat tcgtttcatg
    87901 tgactagatc atactaggca tgaaaaatct ctgaggaaca tggtttccct aggaggtttt
    87961 tcgtgtctat ttttgtttgg ccgcaatcaa ctggtctagc aaacgtgaaa accaaatctt
    88021 caaaaagggt gcgcgcatga aaatcaaaaa gatctttaat caaaatgcag tattggtaga
    88081 tgacggtgga caggaaaaag tagctattgg aaaagggatt ggatttgaca gaaaaagaaa
    88141 tgatttgatt tttgatcgtg atgtcgaacg gatatttgtc atggaaccag aaggtcaaat
    88201 caagttgcaa aatttactta atcagattga tgaacgcttt ttatttgcag cagaaacgat
    88261 cattgatcat gcggaaactg ttttgatgga aaagttgaat gaacatgtat tgatcgcttt
    88321 gaccgaccac attgcttttt ctgcggagaa cattaataac ggtatcgtca tccgcaacaa
    88381 acttttaaga gaaatcgaag tgctttacag tgatgaattc agtattgctc aatgggcagt
    88441 agagtatctg acaaaagagc ttgggattcc atatacttat gacgaagcag gatatatcgc
    88501 aatccatatt cacagcggac gaagcggtcg gaacaataac catcgcagta tccgtgaagt
    88561 gacgattgta tctgacatca tccatttagt ggaatcagaa ttggaaacag atatccattc
    88621 agaaccattt tcactgaatt attcaagact ggtgaatcat ttacgactgc ttctacaacg
    88681 aacccatgcg caacaatatg ctgttttaga cacggaaatc gtagaaatgg tcaaacgaaa
    88741 atacccagaa agctataaga tttctaaaaa aatccgtgtg ttgctgacca aagaatacca
    88801 gctcgcgatc acgaaagaag aactgggtta cttggccatc catatcgagc gtttaagaag
    88861 cgcaatcgta caaacaaatg ttaacaatca tgaggaggaa aaaaattgaa agcatatcta
    88921 caacgaatgg gacgttccct tcaacttcca gttgcggtct tacctgctgc tgctttacta
    88981 gtagggatcg gaaactggtg ggcatcttat agtaacgaca ttgtcgctca ttttttacaa
    89041 gctggcggta acgcagtttt aggtcaatta cctttgctgt ttgccgttgg gttagcacta
    89101 gggatgtcag tggacaaatc aggtgctgct gccttggcag gtttggtcgc atttgaagtt
    89161 ccagtaaatg ttttaaaaac tgattcagta gctactttat tgaatatcaa accagaatca
    89221 gttgatccat cttttgctca gatcagtaac gtatttattg gtattattgc cggattgatt
    89281 gcggcagctc tttataatcg tttccacgaa gcaaaattac cgatggcttt atctttcttt
    89341 agcggcaagc gtctagtgcc aatcttggct gcctttgtca tgttgctgat cagtgcagtg
    89401 ctactgctcg tatggcctcc ggtttactct gctttagttt cttttgctaa attcattttg
    89461 agtttaggct ggggtggtgc aggtctttat ggcttcttca accgtttact gatccctaca
    89521 ggattgcatc aagcaatgaa ctccgtgttc tggtttgacg tagcaggaat caatgatatt
    89581 ggtaaatttt tggcttctga aggaacaaaa ggcgtaacag gaatgtatca agctggattt
    89641 ttcccaatca tgatgttcgg gcttccagca ggagcatatg ctatttacag aaatgcacgt
    89701 ccagaaaaca aagcaaaaac agcttccttg atgttagcag cagcttttgc ttcattcttt
    89761 actggtgtaa cagaaccact tgaattctca tttatgttcg ttgcttggcc attatatgtc
    89821 ttgcatgcaa ttttcactgg gatttcttta gcagtgagtg cattcttcca ttggacagca
    89881 ggatttgcct ttagtgccgg atttgtcgat tacttcctat ctttgaaaaa tccgattgcg
    89941 aatcagccat tgatgttgat cgtccaagga ttagtaacag cagtgattta ctactttggc
    90001 tttaactttg ctatcaaaaa attccatctg atgactcctg gccgcgagga agcagatctt
    90061 tcagatgacg atactgcaac gactaattca gacaataaat atgcggcaca agcaagcaaa
    90121 atctacgctg cattaggcgg agccgacaat gtaacttcta tcgataactg tactacacgc
    90181 cttcgtttgc aagtcaaaga tacaggcctg atcgatcaaa ataaaatcaa agccactggc
    90241 gtacctggta tgaagatcat cgacggaaaa aatgcgcaag tcatcgtagg tacagaagta
    90301 caattcgttg cagatgagat ggcaaaacta catggtggtg ctgcaacacg acctgcacaa
    90361 acaaacaccg tggttaaaac agaaacattt gccggtggaa cgatcgaaca agatatttac
    90421 gctatcgcaa atgggaaact gattccaatc actgaagttt cagatgatgt attcgcggaa
    90481 aaaatgatgg gtgacggcta tgctgtatta ccagaaaatg gagaaatctt ctctccaatc
    90541 gctggtacga tcacaaacat tttcccaacg aaacatgctg tcggaatcca aacagatgct
    90601 ggtatcgaag tcttgcttca tatgggcatc aacactgttg acttaaaagg cgaaccattc
    90661 actttatatg taaaagaagg tcaaaaagtc gcaagaggtc aattgattgc tttagttgat
    90721 cttgccgcta ttcaatctgc aggcaaaaac acggatatgg tcgttgtatt cacaaatggc
    90781 gacaaagtcc aaagcttaga aatcgaaccc gcacgtgatg taaaagcaaa tgataaaatc
    90841 ggctctgttt ccaacaaagc ctgagccatc gtcttcccca gactttttta tcgataaaca
    90901 aacaggagct gagacaaaaa tcttgtctca gctccttttt ccgaataaaa acggcgttct
    90961 cctgccaact ccgcggtaat aagtccagcc aaacgtaaca tatgaagagc tattttttat
    91021 ttgactcttc ttattacttg atgcagaaca gcttttttac aacctctgat aaacggtgtt
    91081 caaaaaccag tttatcggta tgaagtcaaa tttatgcaaa aatgtggaaa gccattttca
    91141 caaaattttt cttcatactc aaaactaatc ggctttttca caacctcttt atacattatt
    91201 cctgatccaa tatttctttt aatgctgctt caagagaagt taatggtttt cccaatactt
    91261 tttctaaatc atcagaggaa atagctaact gatccttttt aatatcatgt tggatcgcta
    91321 aaaacatgtc agctgcttct tgagggaatc cggcttcttt tagattttcg acaaacgctg
    91381 catcacttgc ttcaataatt tctaactttt tacctgtcgc acgctctaat gccttggcta
    91441 attcttcata gtcagttaga ttgccggata attctaagat ttctggagag tcactttcta
    91501 ctagtacttt tgctgcagct tctgcatatt cacgtttcaa tgcccaacct gtttttccat
    91561 ttcctgcagc ataaacgaat tgaccagttt ttaaagcctg cccaatgata ggtaattcat
    91621 tctctacata ccaattattc cgtaaaaatg tatgggaaat acctgaatcc ttaatcattt
    91681 tttcagtgaa ttggtgatct ggcgctaata cactgatcga gtgatcggca tctgcaaaac
    91741 ttgtataagc gatataagat accccagctg cttgtgctgc cttcactaca ttcttatgtt
    91801 cggcttgacg atttcctgga acgccagaga caaaaagcaa tcgatctatt cctttcaacg
    91861 cttctttcat tgagtctaaa tcatcataat caccaatacg tatattaaat ccagcttctt
    91921 tcagtgcttc tcctttttct tcactacgta ctagtacata gatttcattt tgtggaacca
    91981 tcttttttaa gaattccagc gcataaccac caaaacctcc agttgctcct gttactaaat
    92041 aatgcatatt tgccactccc tattcttttt atttgttaag atttacagct gtacatttat
    92101 aaattacacc tttatcataa agagtgtggt aagataagtc aagcaaaaaa aatgaaagga
    92161 tgacaactga tgaagtattc tctgcaattt agtgatgcaa tccatgtact tgcctatatt
    92221 gaaatgtttc aagatacccg atcactttct agtgagatga ttgccagtag tatcgaaaca
    92281 aatgcagcaa atgtacgtaa aatcatgagt cagctcaaaa aatccggttt gatctttaca
    92341 aaaaccggaa aaccgcagcc ttcccttgcc aaaagtccag atcagatttc tttactagat
    92401 gtctatcgca gcatcgaagg taatacacag cttatccaag tcgatccaaa aacaaatcca
    92461 aattgcgtcg ttggtgcgaa tatccaagaa gctttagaag aaagctacgc tcggctgcag
    92521 aaaaaggcag aagaagaaat ggctaagatc acacttgata gtctgataca taaaatagcc
    92581 gttttggaaa aagaaaaaag accagaaaac acaggcctcg tagagagatt tttataattc
    92641 tctctactgt gcctgcattt ttctgatcgg aatcgtctac ataaattctt ttattctccg
    92701 ggggacaaaa gccttgtcat gccccttttt cctctctaat gctcaggtca aagcgctgaa
    92761 gtcatgacgt cttgataaac ggtgttcaag tagctgaccc tcggcattag ttctgaaaaa
    92821 tgcaaaatat ggaaagctat ttcccatttt tcctctctaa tgctcaggtc aaagcgctac
    92881 tttcacgacc tctatattat catggtttat tgactaccgg tatccagatt tctcccatat
    92941 atttcccgtt ggtaactccc atttcgacta cagcatttgg acccccaaca taggcgtaat
    93001 cttctacttc tcttaaaaca tgcccaaagg ccgtattcgt caaatcattt cttaattctt
    93061 caggcgattc tgctaaagcg attacaacaa gatacgttcc ttttgggaat gggatgattc
    93121 gggtagtgtt tggaacatcc tgactcgttt gaacaccgac atagtacatc attttcccgt
    93181 tatagggttc gttgactgta aagaaataat gattttcagc agcttgtttc aatgcatcta
    93241 ttgttccatt accgataact ttttgctcaa atgcttgttt ctctgcagcc aaaccgacaa
    93301 aatccgtatt gctactcttc aattccacac caatacccgt caccgtaaaa tctggttttt
    93361 cttcgatcct atactttgcc atttctccca ccctttctat tatattaagt tcatcttaca
    93421 taaaattaaa gggaaatgac acgattacgc tcttttttct agggatattt ttatttttta
    93481 actatttttt tgctttcact gcaatccaaa tctcactgta aacattactg aaatcctctc
    93541 cccattttgt aaaagagatc tcgggagctt cgactaactc ataatctgaa gaaggaagcc
    93601 attctgcata gattttcccc caagtatctt gtaaagtttg gggaaatggc cctttattag
    93661 gaaaaatggc ccaagtgtgt tcttctatag caagcatttc taaatcagcg tacggatttt
    93721 cttttgtcgt agcaaagcca atcatgtgca tcaaactgcc cttttcttcc aagcgggctc
    93781 catcaaatcc ataagaaacg ttgattactt gatttggata taaatctcct aacttatgca
    93841 tctcttccct ttgagtctcc gtgatcgtct gcgctaactt ttgtatttct tgattgactc
    93901 cttcaaattt gacaggaact tttttcgcca cacctgccac ataaaactgt tctttctttt
    93961 cgatacgaaa ttccatcgat tttcctcctc tgacatcaat aaaaaatgtc aagcgtggaa
    94021 aagatttttg tatgccgtat ctgctgattt ctgaaggcag atatcctgac caatcacgaa
    94081 aagctcttga aaaaccttcg actgtttcat atccatatct aaacgccgtt tctgtcactc
    94141 ttgatccatc taggagatcg cgattagcca aagccaatct acggtttttg atatagtcca
    94201 ttagcgacat ccctgcaata aacgtaaaga tgcgttttaa ttgatattca gagattcctg
    94261 tattttcggc tattatttta taggaaagtc cttctgtcaa atgttcttcg atgtaatcga
    94321 tcaattggtt cagatcttta agcatattta tcttcctcct tgcttgcctt tttatcatat
    94381 tatcaaagaa agtcaattac ttgatgaatc aggaaccaat ttagtcagat gtagaaaatg
    94441 ttgtatggat ctaaagaaaa ttctcaagca gcgtttcgta acggataatt ggtattatct
    94501 gcctatctat gttttacctt tagaaaaata aattttgggg aagacacatt ctaagtaaac
    94561 aaagcggtaa aaatatcttt tattccctta gttaatccgc ttactaccta ctgtacaaag
    94621 caaattgttg ttcaaactgc tgatcagaac gctgcttgga tttttctttg cgatacatca
    94681 tacctctttt atcaattgga acaattattt atttctaaca aaatcacttc atttttgtca
    94741 gataaataaa aaacaaaaaa agttccatct ttaaaacacg ctattctttt actttttctc
    94801 acattctcta agaaaagaaa aggagaatga atttttgaca attcgagcaa aagtgattat
    94861 caaatatgta aaatcagcta cttttttctt aaacgtttct ttatactaaa tataaataag
    94921 tgtttcatga aaggagaact agatgaataa ttggcttgag tattttcctg aaaacgtttt
    94981 ggaacgcggt tacagctatc atctgcacgg ttttgtccgt catttgaact atacaagcaa
    95041 gtacttgtcc gcaacagttt ctggcacgga agattataag gtagtgatca cttgggatga
    95101 aaagaccaac atgacttgtg attgtctata tgccatagaa ggaaaaaaat gcaaacacat
    95161 ggctgctgtc ttattcgctt acgaagaacg tccaataaaa aaatccaact actcactttc
    95221 cgaactctcg tcccttgttt cctccgctag ttcctctctt gtacgggagc ttttaacaga
    95281 gattcttata gaacatccgc aatttatcga acgcttcaaa gttaagatgc catttcatgc
    95341 aataaattat tcagataaat taacaactat catccataaa tacgatcata ttatcaagaa
    95401 aaacaaaaac aggaaaacag cgaagttcat catggagatg cgaaagttca tccaagaagc
    95461 agttgaatcg ctcattcagc aaaatgccta tcttcccgca ttcgaattga tcaatgaagt
    95521 gattgctact ctcgaaacat tctattggga gcctgaggat gaacgaaccc ttcttctgat
    95581 agaggactgt tattatttat ggaaagaatt attagcagaa gcacctcatg cagaaaaaag
    95641 gcaaatgttc tcttggttcg tctgccaagt cgatcatact gacgcctctt attcaaaacg
    95701 ctactccata aaaatcctga aagaagactt tcgggaaaaa gaattttcta accaaaagaa
    95761 aaaaatagat aaaaaaacta aagaaacggt aaagaaagac gatttcaatg aaaaatagca
    95821 agtaaacgat aacaaccatc ctaaatccac aagaaataca gcagaccttg ctttaaaaac
    95881 acgaatcatg caaaggatga agtaaagaag acttaacgcg tacccaatat tagtcatttg
    95941 actattaggt acgcgttttg ttttataagt catgacaaat ttccttcgtt gctgggtaga
    96001 ttttccggca ttgttgatag attttatgat acttttctac attttgtaag agaggttcca
    96061 ctgcatctgt atattggata aaattctgac aacaactttc aggtgtgtcg aaccactcta
    96121 atctttaaag ataaatatta aaataacgat taataatatt aacagtcttt atttttcacc
    96181 accaaaaacc tatctttgca tatactaaat agacgtatat acacagatag gtttgtcttg
    96241 tgaaaaataa tgattatcct taccaaaaaa tgtttgtttt tctacatgtt cgtacttatc
    96301 aaaaaatatg atccttattg aaattactgg ctatttatat tccaacgact tcttgtgtta
    96361 atttttgtta tctcatagta aattatgttt cattttcact taatttagtt gtcacgtgtt
    96421 cgtcaattcg taaaaacggt aaatatataa acacacttgc ggctataatt aatatttgta
    96481 aaacagctgc tcgccagtct ccggctgttg ctaaaaatcc cgatataact ggtggcgtag
    96541 tccaaggaat ttgcactact acatgattaa ttaatcccac agcagttgca aaatatgcta
    96601 ctgtcaaaga aaaaatcggt gcaagcacaa agggaataat cagactgata ttaaatacaa
    96661 taggcaatcc aaaaataata ggttcgctta tattgaatat agcgggagtt accgataatt
    96721 tagcaaagtc cttataatct tttctacgac tgaagataaa tattgcaatc aataaagcaa
    96781 tcgtatttcc cgatccaccc attaccgcaa aggtatcttt aaaggccata ttgataatat
    96841 gtggaatttg ctctttgttt gcataagctg ccatattttc ttgcatattc tgaatcaaaa
    96901 acggatctaa caatgaacct gatattactg cttgatggat accaaatcca aaaaatagat
    96961 tagcaataga tgtaattaac aaaaatcctg gtaaaccagt tgtaatttta cttaatggct
    97021 ctgtaactat cgtggtaatt agcttattta tatccatatt aaacaattga atgattataa
    97081 atgacaataa agcaaacgag gtaatcgtaa taatgattgg gattaataca ttaaaagact
    97141 ttaaaacagc gggaggaata tttccggata gctgaatctg tagtttctta ttattagaaa
    97201 gtttaataaa taattctgta gccgctaatc caacaaatat acctacaaac attcctgaag
    97261 ctcctgtata ggatataggt atcacacccg tcacttcaac agctttatcc gcattttcag
    97321 gagtaaacat catctgcata ggtgttaata caacaaatgt cgaaatagca actaataccg
    97381 ctgcaatatg atttgtataa tttctgcttg cacacatatg ataagatact gctgctacaa
    97441 ctaataatgt agttatgctt aatgtaccat tggcaattga agtaccaatt tgttgtaacg
    97501 tggtcaatgt actagtatcg acaatttccc ccatgaatcc tgttggttct aagatcactg
    97561 aattaataag tgtcacaaat cctgctaaca tcataaatgg cataaatgta gcaaacgcat
    97621 ctcgcaaagt tcttaaatgg atctgattcc ccaacttagt cgcaactata ccaaattttt
    97681 caaatacaat gtccttcctg ctacttttgc ccatattttt tctcctttat gcttattgta
    97741 atcgattact ttttccaccc aaataataca tcacttatca aaaaaagtaa atacttttaa
    97801 ttaaatatat atatcttttt tagtataaaa aaataagctc tgaaaaaata attttcccga
    97861 gcttattttt caacaaaaac agcttcaaaa acaaagtctt gatataaatg tctcgatacc
    97921 gaatactcga aaggtttacc agacgataga gcaacaactt tgtctatctc aatcataaat
    97981 tcacctggat ctatttttaa tatttttgcg tcaaattcat tcgcagtatc tcctttgata
    98041 cgtatgtgcg aagtctttat ttccagaccc agttcatttg tgatataagc atatacagat
    98101 ttctttaaat gttttggttc caagcctggt atgactgcta atggcatgaa tgtttgctca
    98161 atcgagtatg gttgacaatc aataaaacgg cttcgtacaa tattatatac atagtctttt
    98221 acactgatac ttaatttatc agctactttt ttcgatggaa gttcaattga gaaagtatgg
    98281 atttctgaat ctacgtgttc ttcaccaacc acgctaaaca aaccttcgtt tggaccaaga
    98341 actcgtgagt tatcaattgg tgttctgacg acttcagtcc catacccact tctacttcgc
    98401 aaaactcctt cggaaacaag taagtctacg cctttcttta ctgttaactt gcttgtatga
    98461 taaataactg ccaattcatc tcctgtagga agtttctcac caattttata ctctccattt
    98521 acaatttttt tctttatatc taagtaaatt tccatatact tcgcaatttt tttcaatggt
    98581 gaccctccaa tcaaaaacat atcttcatct atactttaac ataaataaac cgataaaatc
    98641 cacatcaaaa ttatacacac aataaaaaag atatatatat ttaaacaaaa ctatttactt
    98701 taagttgtaa gcggtgttat cattaagtgg aaacaggagg taaaaaaatt atgacaacta
    98761 tgaaaaagct aacttttcca gatgattttt ggtggggttc cgcttggtca gctgagcaag
    98821 cagaaggaaa aggagaaaca ggaaaagcag agactatctg ggatcgctgg tttaaagaac
    98881 aaccttaccg gttttatcaa cgaatcgatt cctctattac aaccgatcac atccatcaat
    98941 ataaagaaga tatagaacta atgaaaaaaa ctgggcataa ctcctttcgc gtttctattt
    99001 cttgggcacg aatgtttcca aatggcggta ccggaaaagt aaatcccaaa gccatttctt
    99061 tctatcgaaa attattttcc gaaatgaata ataacggaat caaagtattt gccaacttat
    99121 atcattttga catgcctgct actcttcaag ataaaggagg atgggaatca cgtgaagtag
    99181 ttgatgctta tgttcattac gctgaaactt gttttaaaga atttggtgac ttagtttgtc
    99241 attggtttac cttcaatgaa ccacttgggc ctattttagg tacttatctt gaagattttc
    99301 attatccaaa cctcattgac tttaaacgcg gagcgcaagc agcattcttc actatacttg
    99361 cacacgcaaa agcaatacaa gtatttaaag aactagctct tcctagtaaa ataggcgtta
    99421 ttctaaattt gagtcctact tttcctcgta gtcaaaatcc tgctgatgtg aaagcagcag
    99481 aaatcgctga tttattttat acgcggagct ttttagatcc tatggttaaa gggaattttt
    99541 ctaaaaagct tatcctgtta ttacaagaat ataatcagct tcctgaagat tatacgaaag
    99601 aagatcttgt atgtatctac gaaaataccg ctcaaattct tggactaaac tattacgagc
    99661 cacgtcgcgt caaatctcgt tcttctatgg tggatacatc tagtccattt ttaccagagt
    99721 ggtttttcga accacatatc atgcctggac gacgaatgaa cgaataccgg ggatgggaaa
    99781 tttacgaaaa aggaatttat gatttgtgca tggatatcaa gaaccattat ggaaacatcg
    99841 aagcatttat ctcggagaac ggaatgggcg ttgcggatga agaacgtttc atggatgata
    99901 cagggcaaat aattgatgat tatcggattg agtatatcaa agatcatctt gcttacttat
    99961 ggaaggcaat aaatgaagga tgtaacatta aggggtatca tctttggaca tttattgatt
   100021 gctggtcatg gatcaacgcc tataaaaacc gatatgggct ggtttcactc gaccttacta
   100081 ctcaaaaaag aacaattaaa aaaagtggcg aattttacaa gcaattaagt gatacaaatg
   100141 gatttagata cgatgtagac ttgttagttg aataatattc taaaattcca cttgaagtga
   100201 acacattaga aaacaagaat aatgagaaat accaataaca aatacttttt cttcatactt
   100261 catttatact tgtcagtata agagactgtg acaaatgtag tgatcctcag aagttaggtc
   100321 tggaaatcta acttgagaag atttttttaa actacgtcca gtctttttta tttgtttaaa
   100381 attgaagttg acaagtcttc attaaaaatt tagaatattc acaagtttga cgacaattat
   100441 gaaaatttat gtcgtgctaa aggagttttg ttattggatg aaaagttaga tataaaaact
   100501 gcgatcaaag acacgttacc taccgttttt ggttatatcg gtattggact tgcatttggt
   100561 atcgttggga aagctgccgg gtttcatccg ctggtcgtca cgttgatgtc cctgctgatc
   100621 tatgctggtt ctgcccaatt tatcacggtc agcatgcttg ctagccatag tccactgctc
   100681 tccatcgttc tctcgacctt tctagtcaat tcccgaatga ttctgatgag tatgacgatt
   100741 gctccttatt tcaagaaaaa tcggctgctt caaaatctgc tgattggcac attgctgaca
   100801 gatgaaagtt tcgcactggg aatgaataaa ttgaactata ctggacaaaa gttaaacttt
   100861 cgttggatga atacagctaa ttggatttct tatttgacgt gggtgggttc ttctcttgtt
   100921 ggcgcacttt tagggaattt tattactgat ccgaaaaagt ttggtttgga tttcgccatc
   100981 gtcgctatgt ttatcgggtt actttatctt caagtcattt ctgatagaaa cacctctaaa
   101041 cgattacagt tgatcctgat tggtctcact ttgattctgg tatatgtcgg actgattttt
   101101 atcccaagta acttagtgat tttagttgta acactgattg ggtgcggatt gggggtgtgg
   101161 atcaaacatg ccttcttttg agtttacatt gctgactatt ttaggttgta ctttagcaac
   101221 ttggctttct aggatcctac catttgtctt actgaaaaaa ttcgatttgc cgcaaccgtt
   101281 gcttgagtat ttaagttttg tcccgatcgt cattatgtct gctttatggt tcagcagtct
   101341 atttacccaa aatatcggac atctgccgca gatcaatctc gaaaatgctt tggcttcagt
   101401 tcctacactt ttagctgcta ttctttcaaa aagcttattg gtgatcgtct tggtaggaat
   101461 tctttccctt tcgttgattc gcttattata aataaaaaaa caagagctta tggcaaatta
   101521 ctgtcatgcg ctcttgtttt tatcaaagtc aaataagaaa aaaatcggcg tattcttgct
   101581 tatccgttga acggaccact aacaacgact tttcctaata tatgtcctgt ttctacgtct
   101641 ttggttgctt gtttcaagtt cttcgcattc atcccatctg aatagacctt gctcaatgta
   101701 ctgcggataa tcccttcatt tgctaaagca gcaatgtgcg ctaaagcttc tccttgcgtt
   101761 tcgatttcat agttatagtc tgttttagcg aacatatact cccagtcgaa gctgatagat
   101821 tggtttttcc aaacacctat atctaacggc tctttgatcc ctacgatcgt tcccacatgt
   101881 ccaaatggtc ggacaaggtg tttgatttga tcaaagtagc gggtaatatc gaataataca
   101941 gcgacatact ctacttgatc gattcctaat tcacgaaaac ttttacttaa gtcgtgatga
   102001 taatcgattg gatagtctac acctgttttt ttcagccatt caaaattctt cggacttgca
   102061 gtcgcgtaga cttctaggcc agcccaatgc gctagttgat tcaaaatcga accgacgccc
   102121 ccagctccgt tgatcactaa gatttttttc ccgcggttgg cattttcttc tggagtcaga
   102181 ccaaattttt caaataacaa ttcataagcg gtcaatgagg tcaacggcaa ggctgcggct
   102241 tcttcatctg aaagattttt tggtgcaaga gcgacaatac gttcgtcaac cagttggtat
   102301 tcttgattgc ttcctgctct tgtcgttgta cctgcgtaaa aaacgcgatc gccgacagaa
   102361 aatttttgca cttcatcacc tacagcaaca actttcccga ctccatcaaa ccctaagata
   102421 cgtaaagcat ttcttatccc gttatcttgg cgaagtttcg tatcgacagg attaacagat
   102481 actgcgttga cttttaccag aagatcccgt gaactgggta caggtatctg ttctttttca
   102541 tcaataaagc tttttggatc atcgatcgac aacccttcat aaaaaccgac taccttcatt
   102601 aattcctttt ctgacatacg aattcctcct tagcttcatc aagttggagc atccatacag
   102661 ttttcatttc aatatatata gtatgctatt tgttccactt ttattcatca taattattct
   102721 cttacttaaa gtaaactatt tgcacttttt tggttaaaaa agaggttgcg acaagacttt
   102781 tgtcacaacc tcttttaaac ggtgttcaat caactgaccc tcggtattcg ctcaaaaaac
   102841 gacaaaatat gaggagctat ttttgtttgg ctgttcttat tacttgatgc aggacagctt
   102901 tttcacgacc tctaattcac ggtgttcaag caagaaatca ttgttcactg aaaagcgttg
   102961 gatgttcttt ttcaaaggtg tctaagatct ctcgtacttc atcagtagat ttcgtattca
   103021 tcaactgaac tcgcaagtca tttgctcctg gaaatccttt gatatagatt ttaaagaaac
   103081 gatgtagtcc tgtgatggaa cgcgggatga tttctgaata atgatcttgc agatctagtt
   103141 gcagacgaag tagtccgatc agttcttttt ctgtatgttc cctcggttct ttttcaaatg
   103201 cataaggatt cttgaaaatc ccccggccaa tcatgatgcc atctacgcca tatttttcgg
   103261 ccaattcttc tcctgtctgg cgatctggga tatctccgtt gatcgtgatc agtgtttgcg
   103321 gagcgatttg gtcacgtaaa gcaatgattt tagggatgac ttcccaatgt gcatctactt
   103381 tactcatctc tttacgcgta cgcaaatgga cagaaagatt ggctatatct tgatgaagta
   103441 ggtgactgat ccattcttcc atctcagaca tttccgtata gccgatacgc gtcttgacgc
   103501 tgacaggcaa accgccagct ttagccgctt caatcaattg tgccgctact tctgggcgaa
   103561 ggatcaagcc actgcctttt ccacgttctg ctacattagg gactgggcag cccatgttga
   103621 tatcgattcc ttggaagccc atttctgcca tagcaatgct catttctcta aaaaattctg
   103681 gcttgtctcc ccaaatatgg gcaaccatcg gctgttcatc ttctgtaaag gtcaatcttc
   103741 ctcgtacact gtcttttcca tctggatgac agaaactgtc tgagtttgta aactcagtaa
   103801 agaagacatc cggtgctgct gcatgcttta cgacatggcg aaatacaaca tctgttacat
   103861 cttccattgg tgctaaaaca aaaaaaggct ttggcagctc tttccaaaaa ttagtagtca
   103921 tttatttgtt actctccatt ctatcaagca gtgaagtcgc aatctttctc aaaaacattg
   103981 tcattatact aggaaacaaa aaaagaagca aagtgaacag cttaaaagat gtttctgatt
   104041 gagcaaaaaa agactgtgac aaaaatctta tcacaattcc ttttccggaa taaatggtgt
   104101 tcaaaagctt gcatctgcgg taataagtcc aaccaaacga aaaataggag gagctatttt
   104161 tgtttggctg ttcttattac ttgatgcaga acagcttttt cacaacctct ccactaaacg
   104221 gtgttcaatc agctgaccct cggtattagc tcaacaaacg acaaaatatg aggaactatt
   104281 ttcccgtttg tttctctaat actcaggtca aaacgctgat ttcacaacct cttttctaac
   104341 ttctcaatcc tcttccttta ttgatcaaat accaagtaac ggcgtacaaa acaacgatga
   104401 atagcacaag tacgatcatc gatgttgcta ctggcacatc gattgttcca aggaatccgt
   104461 aacggaaacc gaagatcata taaacgatcg gattgacttt cgaaacagct tgccaaaatg
   104521 gcggcaacat agagatggca tagaaaacgc cacctagata agttaacggc tgcaagacaa
   104581 atgtaggcac gatcgataca tcgtcataag actgagcaaa aatcccgttg agcagtcctg
   104641 ctaacgaaaa caagattgcc gtcatcaata atgtaatgat gaccatgaac catgaataca
   104701 catgaagtgg tacaaagaac aaggaaatga tcgttacgag agagccgacg agaatactgc
   104761 gacccactcc gccaatcaca aagccccaaa tgatcacatg cgtaggaaca ggcgctacca
   104821 agatttcttc gatgtttttc tggaattttt gagagaagaa ggacgaagaa acgttggcat
   104881 acgaactagt gatagcagac atcataatca aaccaggcac gatgaattcc atatatgaaa
   104941 aaccacccat gtcaccgatc cgaccaccga tcatttttcc gaaaataaca aagtacaagg
   105001 atgtcgtgat cacaggcgga accagtgttt ggacccagat acgcaaatag cggttcgttt
   105061 ccttgatagc taaacttttt aatgcagtaa aataaagatt aaacattttt ctcctccgta
   105121 tgattatttt cttctgtgat tttcaaaaac agttcttcta aacgattcga cttattcctc
   105181 atagaaagaa ctttgattcc ttgtcttgtc agctgatcga agattccgtt caccccttga
   105241 tttcgttcaa cttcgacagc gattgtctgt tcatcttcaa atgtacaagc gtatccttca
   105301 atcacaggtt tggtctcata tggcgctaaa tcaaagataa atgtttcaaa ttgcagtttg
   105361 gatagaagct ctttcatact agtattctcg atcagttcac ctgattggat gatcccgatg
   105421 ttgcgacaaa gcatttcagc ttcttctaaa taatgcgtcg tcaaaatgat cgttgtacca
   105481 ttttcgttca attctcggag aaactcccac atctcgcgtc tcaattcaat atcgactcct
   105541 gctgttggtt catccaagat cagcaaacgt ggttcatgca tcaatgccct agcaatcatc
   105601 agtcttcgct tcattccccc ggaaagcata cgtgcacgga catttctctt ttcccaaaga
   105661 ttggactgct tcaaatattt ttcgctgcgt ttcatcgctt ctttgcgaga gacaccgtag
   105721 tagcctgctt gattcacgac gatttgctgg accgtttcaa agggattgaa attgaactct
   105781 tgcgggacta atccaatctg ttgctttgct cggactagat ccgtatccag atcataaccg
   105841 aagacattca cttttccaga tgttttattg actaaagaag taatgattcc gatcgttgta
   105901 gacttcccag ctccatttgg tcctaatagc gcatagaaat ctccttcttt cacggaaaga
   105961 tcgattcctc gcaatgcttc gaccccactt ccataaacct ttttcaaatt atttatttca
   106021 agcgcatttg ccatttattt cctatctcct tatagacatg attctttatt gtatcatgga
   106081 atacagcaga tgaaaaaaca acttggttcc agcgaaaaat caggttgctg ggctcaggaa
   106141 aatctcctaa tgaaagacat caatcggacg aagtcagaca accttttcag aaaaaacaaa
   106201 tcgaagataa aggattacta ttcatatgtg caacaaaagg agcgtgagac aaaagtaaag
   106261 aacacttttg tctcacgctc taaacacgta taaacggcgg aagcaaaagc caagattttt
   106321 gatccaataa atactttcga tcacttcgcc tatcccaata catgccactg ccgcttttca
   106381 tcaaataacg cggcttccgt ttttgcggtt tctactaaag tctctgggta atccaaaact
   106441 ttcagcaagg caatcgcatt tcgggtcctt gaaggtcctt cttttaattt gaaatcaaaa
   106501 ctgattcctt ttccttctgt tacttgttct tcaaagtgga cattctcaca ataattcttt
   106561 aaaatctctg tcaattcgat atcatgtgtg gcgacaaatg ctaaagatgg atactccgca
   106621 agccaccgaa cgactgaagc ggaagaagca atccgttcga tcgtatttgt cccttttaaa
   106681 atctcatcta cgaagcagta gcagcgttct ttggaagcca cttggtccaa caaacgtttg
   106741 atcgatttga tttctgaaac aaaataactg tcgccttcaa ataaatcatc ttcgattgcc
   106801 atggaagtca acacatgtcc aggttgcagg gtaaactgtt ctgcaatcgc tgtttggatc
   106861 gtctgtgcta gaatacagct gatggctata cttttgacat acgtagattt tcctgatgca
   106921 ttggaacccg tgactaatgt attcttctgc cagttgaccg gattcactac cgcttctttt
   106981 aacaatggat gatagatatc tttcgctgtc acaccgccct cagtaaactc tggtcggcaa
   107041 gtgatgggca tataagtacg gtaattcaat attgcagcgg ctacttctaa ttctcccagc
   107101 aattcccaca gcttgatggc ttcagttgaa tgcttttcta atttagtgag aacgaaatga
   107161 taggagataa atggcagcat gaacatgatg ttgacatatt caaaaatcaa ctctgcttca
   107221 ctcccactct tcatacgaaa tgaaaaacct aatttaggga tgtctcttaa tggtttagtt
   107281 tgctgtttca gctcttcttg aagtggtgtc ggcagttttg ctagctgatt ggcggctgaa
   107341 atcgttgaaa ccaaataact catgctattc agctctgttt ctagtgtttg tttcttcact
   107401 agataataga ccgtattgaa tactaaccca ccgattgcca aatagattcc tagtacttgt
   107461 cctaaaagaa gcaaacccaa acccaccagc ggaagcaagc caagaaaaat aaataaacct
   107521 acgcgtccaa tctttttact ttttccatcc gctagatatt gttttgcaaa attatgatct
   107581 ttttttccta aacgagcgaa ttgatattgg attttttctc tcagttgagg attttcctga
   107641 taaaaagcaa tcagtttttc taactgctga tcttcaccaa aatcaaagct gcgtaaacgt
   107701 tgatacaacg cttctgaacc tacactagaa taggtactgt tgattccttc gaatacttcg
   107761 aacatatcca ggtcatacca agtaagatca tcgatttcgc tatcccatga acggaacttc
   107821 ttctccgtga gccatgcttc cttcaagctt tcttctttat caaatctcgg ttgataagga
   107881 attttttccc atttgctacg aactgtttcc tttaatttca aacgtgaaaa aatgtctaaa
   107941 gcaactaata aaataacagc tgcaataata attaaaacga taaattctct ttgacccata
   108001 tccctctccg ttcctttatt tgttagcttt agtatagcac tgttgcgcta tttgaaaaga
   108061 gggtaaaaaa acacctttca aaataaaagg tgtttttttc ttgtatatta catatttatc
   108121 tctcatttat caaaattgac aaataatcat agggaggaat tgttgttaat tcttgtttat
   108181 tctccagtgc attgacaact gtcccaaggg aaaggatagc ctcaggtact attttttctt
   108241 gttctgttgg attagctaag cgaagaacaa atccttgttc atgaaaataa gaaggataaa
   108301 tcgatgatac aattaagtct tcaggtaatt caatcaatga aaatttacga ggaacatcaa
   108361 gttcattttg taatggccaa atcttgttat ctaacctgtg aataaataca ttcagtttct
   108421 gcttttgata agaaatagat tgttctaacc gtttttctgc ctgttttgcc actttgaact
   108481 cattaaatct tccttcttct acattaaatc caaaagtgac tttatactca cctatctctt
   108541 gagctagcgg tgtttccatc atgacatgcc cttcatttgt cgtatctcct gaagctcgcc
   108601 caggtcgcca agcaagatta ggttttccaa gttcccctgt tgttgaaaat aaggttatga
   108661 ttaattgatt ttctatacgt tcatactctt ttaaaccatc tgcataaaac gtaaaataat
   108721 gatcattttc tgccacagag acactcttat cgaatatttc taaattaaca ggtttctcta
   108781 ccatagtttc tgaccaattc ggaggaatga catcaggggt attttcaata aatccgtttt
   108841 gaatttgtgc aattgatttt tcagatttat ctaaaacatt aattgctaag cgcatacgat
   108901 gcgagtaaac agtattatga attttgagtg tgccttcaac gatttgactt tctcccagac
   108961 tgaacgatat ttcataagat atttcttcca tttcgggttt ttcagataaa cgatctttta
   109021 aatctttagg aagttgagct tttccgtaaa caactaatgt ttcttgtaaa gaatctttat
   109081 atactttagc tgtttctaat tttagagata gttctgtatc tccttctaat ggtgaataat
   109141 catacgtatc gccatcattt gctgaatcga tcaaatgaac gaaatcaaga tattgtctat
   109201 ctccaactat caaattcaat tgcccatctt taaaagaaag tttatattta ttgttactta
   109261 tctcagtttt gtctatctcg attgctgttt ctaatttttc attatttttc tcaaattcaa
   109321 caacagtgta tcctagtgct ggcacattta catttatttt tatgtcaagt tcataataag
   109381 ctggttcatc aaaatattcg aaacctgtag caatcatccg ataagcattt ttccgttctg
   109441 gaaaataaac ttctttttca atgatattat agggactacc tttgaagtgt attttctttg
   109501 aatcagctac tacatgcacg attttcgatc cactataatt ctcagtcgtt gtgttgaaaa
   109561 caaggacttc attcgatttt agctttaatg catcagccat ccgttttaca ataaggtttt
   109621 cgattccgtc agctatctca ttagcttctt tgattcgatg gaaaatatct tccgcaacat
   109681 tatctgaaac acagccacca atactatcat gagcctggtt ttgcaaaatc tttttccata
   109741 accgacgaag taggccttta ctgatatgga taccatttct ttctgcaatc agcatgagcg
   109801 gctcaactcg ttttagaatt ttttgttcca atttaaaatt ttctattttc atttttgttc
   109861 ttactgagcc aatagaacga tgaacacgag agtaaaccgg ctgacgaagt tcacctttat
   109921 attcaggtaa ttcttttttg tttctgataa cttctacata agaaggataa tctgaaataa
   109981 tattgtggaa tttactgtat ttattcaact tctctacgac ttgatcaaaa tttaaaatca
   110041 ttgacttttg atctacaccc gaaggtacta aaatatcttt gttttttcct tgcatatgaa
   110101 gcatttcaac tgcttcatcc aacttttctt ttgcaaattc aggaatatct ttaattgcgt
   110161 ctaaggtcat cattccagtc atataaccaa atggaaaatt catggcataa acaaatttat
   110221 ctcccaatcc tttccagata aaataaggag atggaaccat cgtttcaaag tttaatcctc
   110281 gccaacacat gaaattatcg atttctactt gatgcaaaag tgtaggcaaa ttcgcattga
   110341 acccaaacgt gtcaggcaaa taccctacca tcattggatc tccatattta aggatcgtat
   110401 cactgattcc aatcattaag tttcttaaaa ttgattcagc atccactaat aaggcatctg
   110461 tttgtgcata ccacggtccc acgaatagtt gtcctgtttt catcagtcgt tggataacct
   110521 taagcttttg cggattgatc tccaaatact catcgacgat tgaagtttgt ccatctaaac
   110581 aaaagtttac tttagggttc ctttccaatt catctagaac ttcagtaaag acctgatcag
   110641 acaatacgat ggcatcttca tttgtaaaat accattctct gtcccagtgc gtgtgttgaa
   110701 ttatatgtgc atttaccata tcagattctc ctactttcct tcttctactg aatttacttg
   110761 ttgttctttt ttatacttga tggattttag tgcattgacc attaacgctg taaccactcc
   110821 cccaataaca attgatacta aatataaagg tatattcgta acaaaaggaa ttgccataaa
   110881 ggttgaaagc attgtttctt gagtaacacc aaaaaatcca tttagaccac atgctactgc
   110941 agtgcccacc acgatgcttg gtattactcg taaaggatct ttcacggcaa acgggatcgt
   111001 cccttcagta atccccacaa ggcccataat catagctgtc tttgcattat ctcgttccga
   111061 ttcatcataa agttttttgt ttaaaattgt tgctaaaaac attccaaatg gcggaatagc
   111121 aattcctaat aacatggctg tactaggtcc aaagcttccg cttgaaaaag aagcaacccc
   111181 aaaagcatat gcgattttat tgataggtcc tcccatatca aacgccatca ttcctcctaa
   111241 aatagccgac atcaaagcag catttgctcc tgacatgcct tctagccaat tagtcagtcc
   111301 tgttgtcatt gcttgaatag gcgtagctag tacataccat aatatgattc caacaactaa
   111361 tgtagtaaca aaaggaatca gcataattga ttttagacta ataacttgca tcggtacttt
   111421 tacttttttc aatgcattag ctaaatagcc acaagctaat ccagcaacca ttcctccaat
   111481 aaatcccata ccaagatttt gacacatcat cccagtgata aaagctggtg ctagaccggg
   111541 acggtcagca attgaatatg cgatataggc tgaaatcatc ggtacgataa actgtaatcc
   111601 cgtctgacca atcattcgca ggactcccca gaatgtatcc gtctggtccc aaacacctgt
   111661 gccaccaaaa atgactgcaa tagaagttag taaccctgct gctacgacaa gcgggatcat
   111721 ataggaaacc ccactttgga aatgatttag aatttctctt ccttgtttct tgaattccat
   111781 tagtaactcc cccacgatat attttttatt tgttaattaa tgcaattgct tcatcaatcg
   111841 tctcttcacc atcttttact acctctgagg tccctactgt taaaatcggt ttaccgtcaa
   111901 agcgacctcg ttctgaaaca tttgtatcta ctgcaaatat gacaacatct gcctcggaaa
   111961 catccgaaat tgaaagtttg ttttctatcc ccatagcccc ctgtgtttct actttaatat
   112021 ctaacccttt cttcttcgca aacttttcta aattagcttt tgccatataa gtatgggcaa
   112081 tccctgcgat acatgctgtt actgctacta tttttgtcat atgaaattcc tccttttaaa
   112141 atgatagagc ttttaccaat tcttttttat ttctcgaatc ttttattctt ttaacaaact
   112201 cgtcatccat caatcttcca gataattctg ctaaaatacg taaatgatta gtacctttat
   112261 cagtgtcttt tattgctaac aaaaagacga gatcaactgg ttgatcatct aatgcgcccc
   112321 attcaacaga ccgctttaac ttggctacag ccactgttga ttcaattact gctaggcttt
   112381 tgccatgagg aatggcgata tttttcccaa ttcctgtggt catatggttt tctctgtcaa
   112441 atacgtcttt ttgaaattgt ttgtggtcag acacaaaccc attagtctct aacaatttcg
   112501 ataatttttc gactacactt tttttatcag atgcatttaa atctatcact atattattta
   112561 tattgatttt ttcactgatc atttataagc cttctttcaa tatataaact aatttttcaa
   112621 acgacgaact cgtttttaaa tttgctaata actcatgatt cgaagcgatt tcattgaatg
   112681 tttcataaat tttattcaat tcaggtttta ctttttcatt aagtgcaaaa aagaaaacag
   112741 aatgaacaag tgtcccatcc caatcaattc cttctggatt aacgtagaca cagattactg
   112801 gcttttttat aaaatctact tcgatatgcg gcatagcaaa atcattcatc gctgttgaag
   112861 atagtttttc tcttttgatt gctccctcta gtatcccttc tttcgcgtaa ttttctttta
   112921 ccaatttttt ggtaattata tttaaaacgt tcacttgatt atcctttatt tggtgggtaa
   112981 aaaagcaaaa tcgtttatct aataaattta gaaaagcatc ttctgtttgt tcatttaact
   113041 gtagatactg ttttactttt ctgacatctg cccctaacat caaaggacta acaacaataa
   113101 caggaaaatt tgtattttca atcggaatcg tgcttataac aagttcatca gtgacttttc
   113161 tatcttgtag ttcattgatg cttagtacat cttctatctc aaccatatct gcaaaaccgt
   113221 tatttattct ttgctctaat aattttgatg ttccatatcc gctactacaa actaatatca
   113281 ctttcgtttt gtcaggtttg taacgatcca aaagtgattg aatatggagt gttacgtaag
   113341 cgatttcatc ttcattaaaa tgtatacaga atctctcttc gatttcctct aataaatcta
   113401 cacttatcat aaatgacctt ttaaaagaat atttgatttt gtccgtataa gggttataga
   113461 tatttactcc caatttgagt cttttaactg ctgcattgag atgtaatact agattattga
   113521 tcaattcttc atcaggataa aattcattta atttaattct tactaactct tgtagctcaa
   113581 cacccatatc taaataggaa agcttcgttt gatctaagtc gtgattcata gcattttttt
   113641 caatcgaagt aatgtgaatg tcaacataag cttgttcatc tattggcaca ataattgaaa
   113701 atgctttttc aatcattttg attaaaataa gtgtattctt tgagatttct tcttcagaat
   113761 tattactacg tgataagaaa ttgcttgttt caatcctttc tatcgcaata gcaaggtgga
   113821 tagctaaagt ttgaaattca taatctgtaa atttcaattg tgtcttattc atgtatcgat
   113881 taagcaattc ggctactttt ttcaatatgt ccttatttaa gaaattattc gcttcaccaa
   113941 tgaaattgat attcaagtct aagagatctg ttttactgtt agatgctgta aagccacccc
   114001 aataatagtt cacaacttct gacatcaacc ttcttttact tttttcatca gctttgatgc
   114061 gcacgccatt tcgatctgaa actaaggaca tcccatgctt gtttagtctt tttctaacat
   114121 ctttcattgt gctttctacc gtcgacctgc tcacgtataa ttcgtcagca agattttgaa
   114181 tctttagaga atcattagta ttcaataatt tagcaaacac ataagttaga cggtcctccg
   114241 gagagtctgc gatattgatt ttatgactgg ataataaatt tcgaagtgtt tctttttttc
   114301 caataagcga aacgcctttt ttaggttgaa ccaacatttg tacatctggc attttttgga
   114361 ttatttcttt caaaattaaa atatctttgc taattgtttt cgtagataca tataattgtt
   114421 ctgataattc tttgtaagtt gtgtgctcat tttcaatcaa aaagtatagt attttcattt
   114481 gccgttcgct aaattcgatg cccattatct tcacctcctg aatacagctt aagtgtacaa
   114541 ttattatctc tattttcata cagaagaaag ttcttgatta atgtagaagt ttctaatatt
   114601 cttgattatt tcaaatcaat aaaaaagcct gcaatattta tatcacaggc ttttttctct
   114661 attaaatata tataagataa tacatttttc tactagttct cactaatctt gtataattaa
   114721 accctccgca acttgacgga gatggagaag atgcccccgt ctaatctagc ggtcatctct
   114781 cctcccattc cttccaccaa tttttttgac aggtaaagcc cgattccgct agattccgta
   114841 tttgtgcggc tggtattttc ggtataaaaa cgctggaaga ctttttcaac agaggtttgc
   114901 gttcctggtt tgataggatt ggccactgtt aatcgaatga atggatcctc ttttgaaaat
   114961 gtcacctttg cttgtccatc tgcataacgc aataaattct gtatgatatt ttgcagcact
   115021 cgcagcaaca tgagcggatc tgctaataca gttgtattta tcgagtgttc agcgaacgct
   115081 acctcgatat ttttctcaga aaattgttca taaaaagaga aaaatacttc ttccacctct
   115141 ttagaaaaag aaagcgtatg gagatccatt tctttttgct tcgtctctat tcgagcaaga
   115201 tcataaaact gatccgtcat actgagtaat cttgcaacag attgtttgat gatcgttaaa
   115261 tacttctccc gtttctccgt atcctctacc tgttccagta attgtacata accgttaata
   115321 gcagtcaaag gagttctgag atcatgagaa aggccgacga tcgatagtct gatgttttct
   115381 tccatttctt gaaatgcttg tcctttttgt tcattttcat ccaaccatgt attcagtgca
   115441 tctactaggt ccattagatt cttttctcga aattcgactg aaagacgacc accatattct
   115501 tgtcgttcag aaagagtggc gattttctta gttaatctct tgatttccct ttgcaggaag
   115561 aaaataaaac ttcccataaa gataacaacg agaagcaaca gccatttaat caaatctaaa
   115621 ccccactccc cacaccgtat gaatatacac agcatgtgcc tttgctagct tccctcgaag
   115681 attggaaata tgcatattca ctgttttctc actatcaaaa tatggttctt gccaaactgt
   115741 ttcataaaga tttgctcgcg aaaatacttt tttcggatgt tctaaaaaaa gcttcagcag
   115801 atcgaattct cttcctgtca aatggacagc cacaccattc acatttacat ccctcgactc
   115861 tttgtccagt aagatttcct tgtaatagat gcgttgcgac agatctttta cttggacaga
   115921 agtctgatga cgaagttgga tgccgattcg taacaaaagt tcttcgatat caaatggttt
   115981 cgtcacatag tcatccgctc ctgctgccaa caaggaaact ttatctcttt gatcgctttt
   116041 tgctgaaaga acgatgatcg gaacattcga tgtctgtcgg atttctgcta acaatgcttc
   116101 acctgaaagc cctggaagca tgagatctag aaggatcaaa tcgacaggat atgtgcttaa
   116161 caataatttt ccttccgtac ctgaataagc atcaagaagt ttgtatctct gttcaagaac
   116221 ctcctccagt aaggaatgaa cagcttcatc gtcttcgata atcaaaatag tttccagcag
   116281 gaccacctac ttaatgtcag atttttggaa aataaacatt cctagagctg atgataccac
   116341 gattgttact agactgacca gaatcatttt cggtgcttgc gaataagttg cttgttgcgc
   116401 aaagtccgta tacatgagcc acgtttccgt aaaccactcc gttagaaatt ccaagccttt
   116461 gatttttgcg aaaacaccgg gaatgaaggc cgttcccatg atataaagaa aagaaagaag
   116521 caaactgaca ctggtacttc tagtgatgaa tgtcaaagcc actggaacag ataatgtccc
   116581 taatgtcagc agaagcaata caggaaatac ttttagaaca taatttccat agtttttgat
   116641 tccctcaact tcaccaaatc cgaaagcaag tgtgtaagca agcatggcta gtcccgtgat
   116701 caaaaccacg ccaagtgttg tgatcaaaag cgtaacgaga agtttcgaca cataataagt
   116761 cattcgattc cgtcctaaag ataacgtatt gcgaatcgta ccgttttgaa attcttcccc
   116821 aatataaaag cacgcaaatg ctgcgaaagc cagaagaatc catgcagcca ttttttctac
   116881 cattaaaatc cctgttgcac cgttgatgac tgtatccgtt gcttggttta attcattgcc
   116941 gtattttgta tgcatatacc attcgttcca agaataaaaa agcggaagta cgaccatcag
   117001 tcctagtgag acccacattt tacggctctt ccatactttt attttttcag cagttaatag
   117061 attaaacatg tggattgcct ccagttaatt gtaagaaata atcttccagt ttttgcccaa
   117121 ctaggtgaat accatccaca ggaacttttg cttctaccaa tgcttgattg atggctgcta
   117181 cttggtcaat tccttcaaaa agctggataa cacggctaga ttgtacaaaa taatccctat
   117241 aaccaagaga gtcgagaacc gttactgctt gttccgtcgc cgaagtgtca atttttataa
   117301 attgacgaga ttcttgtgcc aattcttctt tcgataattc tttgatcaag tgtccttcat
   117361 gcaaaatacc atagtgagtg gcgatctgtg acaattcatc tagcaagtgg ctagaaagca
   117421 agacggtgat gccccgttct tttaccaaac gttggatgat ttctcgcatt tctgccatcc
   117481 ctgctggatc catcccattc gtcggttcat ccaaaatcaa aaattctgga ttcgtgatca
   117541 gtgcatttgc aatagctaaa cgctggcgca tacctaaaga gaaattcttt gctttctttt
   117601 tccctgtatt ttccaatcgc atcattttca gcaggtcttc gatttctcta tccgacacac
   117661 cgccgttcgc tgcttggata cgtaggttat ctcttgcagt taattctgga taaagagcag
   117721 gggtttcaat cgattgaccc atacgtcgtc ttgctgcctg caaatccgtc gttccaaata
   117781 attcgatcga accttcatca atcgagatca aacccataat agttctcata aaggtagact
   117841 tacccgctcc attttcccca atcaatccat agatcattcc acgtttgatt tcgattgata
   117901 ctttatctaa tgctttggca gcaccgtatt ttttggttat accagttgct ttcaagaccg
   117961 tttcatttcc aaaatccata cttatccttc tttcttattg atgagtgaag tatagttgac
   118021 gggtataaag aaagcagcca gaaatgtata aagaaagtgt aaattttcca attgaatgtc
   118081 aaaaaaaaca atcggacaat acgtgtcttt cctattatca ggcagtttgt tatacgcttg
   118141 tatcagtttc ctgattcttt cttttcgacc aaagtcgttt ctctgtattc ctcttcactg
   118201 aaaatttttg cttctttcag atcaagcttg agtaatttta ccagaccggt tataaggata
   118261 actatagcaa gactccctcc cagaaaaatt agactgtctc gcagacgtgg ttgcgttgtc
   118321 ttccaatcaa agagcgcacc aaacagtgct aatccaagtg gactggccac catggtaatc
   118381 gttgttatcg ttgacataag tcgtccttgt atatgcgttg gaacttctcg ctgaagccag
   118441 accatataaa aagcaaaaga aaacattaat ccttaaaaac ggacttatga aaaataatac
   118501 atgccgtttg ggatttacaa ttagctacca aataagaggt tatgacaaaa gacttttcac
   118561 aatcccttct tccgaataaa cggtgttctc ctgccaactc ctcggtcaca agtcacaata
   118621 tttatcaaac atgagaagca atttttgtaa attccttctt atttcttgaa gctgaccact
   118681 tctgtcacaa cctcagaagc ggataaataa tattgtttga tgatacttta tctttttccc
   118741 gtttgtttat agatcgaatg atattataga ccaagaatcc tacctattaa catagctaaa
   118801 aacacaaaaa aggcactttc caaattgtgg aaagtgccag aaaagttagg attaaggtaa
   118861 ctgcgctcag cattgcttcg cccagtacga ttctcgtaac tcgtgaactc gaacgataat
   118921 cgcaattaac gttttgagaa ctgtgaagct ttacg
//
LOCUS       DAXLPC010000002        79036 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.002, whole genome shotgun sequence.
ACCESSION   DAXLPC010000002 DAXLPC010000000
VERSION     DAXLPC010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 79036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79036
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.002"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..1073
                     /locus_tag="ACF3UE_000109"
     CDS             <1..1073
                     /locus_tag="ACF3UE_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633571.1"
                     /translation="VFEKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAFS
                     LLTFYPFFQLLRGEEINRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRY
                     NYKLSVFSIISLAELIFSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKP
                     FFLDMNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNG
                     NKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTS
                     IFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSVQKN
                     EFMQFGLTVLGICTFIITVINR"
     gene            complement(1313..1396)
                     /locus_tag="ACF3UE_000110"
     tRNA            complement(1313..1396)
                     /locus_tag="ACF3UE_000110"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1360..1362),aa:Leu,seq:gag)
     gene            1469..1630
                     /locus_tag="ACF3UE_000111"
     CDS             1469..1630
                     /locus_tag="ACF3UE_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633572.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            1779..2996
                     /locus_tag="ACF3UE_000112"
     CDS             1779..2996
                     /locus_tag="ACF3UE_000112"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFD3633573.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3180..4016
                     /locus_tag="ACF3UE_000113"
     CDS             3180..4016
                     /locus_tag="ACF3UE_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3633574.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            4092..5240
                     /gene="nagA"
                     /locus_tag="ACF3UE_000114"
     CDS             4092..5240
                     /gene="nagA"
                     /locus_tag="ACF3UE_000114"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFD3633575.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            5518..6519
                     /locus_tag="ACF3UE_000115"
     CDS             5518..6519
                     /locus_tag="ACF3UE_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFD3633576.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
     gene            6538..7557
                     /locus_tag="ACF3UE_000116"
     CDS             6538..7557
                     /locus_tag="ACF3UE_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFD3633577.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(7659..8375)
                     /locus_tag="ACF3UE_000117"
     CDS             complement(7659..8375)
                     /locus_tag="ACF3UE_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3633578.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(8344..9129)
                     /locus_tag="ACF3UE_000118"
     CDS             complement(8344..9129)
                     /locus_tag="ACF3UE_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3633579.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(9120..9869)
                     /locus_tag="ACF3UE_000119"
     CDS             complement(9120..9869)
                     /locus_tag="ACF3UE_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFD3633580.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            10167..10691
                     /locus_tag="ACF3UE_000120"
     CDS             10167..10691
                     /locus_tag="ACF3UE_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFD3633581.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            10707..12206
                     /locus_tag="ACF3UE_000121"
     CDS             10707..12206
                     /locus_tag="ACF3UE_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFD3633582.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(12294..12896)
                     /locus_tag="ACF3UE_000122"
     CDS             complement(12294..12896)
                     /locus_tag="ACF3UE_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFD3633583.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            13000..13956
                     /locus_tag="ACF3UE_000123"
     CDS             13000..13956
                     /locus_tag="ACF3UE_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFD3633584.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(14261..15217)
                     /locus_tag="ACF3UE_000124"
     CDS             complement(14261..15217)
                     /locus_tag="ACF3UE_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HFD3633585.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITINKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            15391..15951
                     /locus_tag="ACF3UE_000125"
     CDS             15391..15951
                     /locus_tag="ACF3UE_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633586.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15944..16768
                     /locus_tag="ACF3UE_000126"
     CDS             15944..16768
                     /locus_tag="ACF3UE_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFD3633587.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16778..17395
                     /locus_tag="ACF3UE_000127"
     CDS             16778..17395
                     /locus_tag="ACF3UE_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFD3633588.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            17413..18096
                     /locus_tag="ACF3UE_000128"
     CDS             17413..18096
                     /locus_tag="ACF3UE_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFD3633589.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18779..20062
                     /locus_tag="ACF3UE_000129"
     CDS             18779..20062
                     /locus_tag="ACF3UE_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3633590.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            20078..20965
                     /locus_tag="ACF3UE_000130"
     CDS             20078..20965
                     /locus_tag="ACF3UE_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3633591.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20982..21818
                     /locus_tag="ACF3UE_000131"
     CDS             20982..21818
                     /locus_tag="ACF3UE_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3633592.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21821..22444
                     /locus_tag="ACF3UE_000132"
     CDS             21821..22444
                     /locus_tag="ACF3UE_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633593.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            22441..23733
                     /locus_tag="ACF3UE_000133"
     CDS             22441..23733
                     /locus_tag="ACF3UE_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3633594.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGNVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      24092..24189
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            24305..24886
                     /locus_tag="ACF3UE_000134"
     CDS             24305..24886
                     /locus_tag="ACF3UE_000134"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFD3633595.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24889..26196
                     /locus_tag="ACF3UE_000135"
     CDS             24889..26196
                     /locus_tag="ACF3UE_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFD3633596.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26612..27100
                     /gene="purE"
                     /locus_tag="ACF3UE_000136"
     CDS             26612..27100
                     /gene="purE"
                     /locus_tag="ACF3UE_000136"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFD3633597.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            27093..28217
                     /gene="purK"
                     /locus_tag="ACF3UE_000137"
     CDS             27093..28217
                     /gene="purK"
                     /locus_tag="ACF3UE_000137"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFD3633598.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            28230..29525
                     /gene="purB"
                     /locus_tag="ACF3UE_000138"
     CDS             28230..29525
                     /gene="purB"
                     /locus_tag="ACF3UE_000138"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFD3633599.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29705..30082)
                     /locus_tag="ACF3UE_000139"
     CDS             complement(29705..30082)
                     /locus_tag="ACF3UE_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633600.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            30338..31066
                     /gene="purC"
                     /locus_tag="ACF3UE_000140"
     CDS             30338..31066
                     /gene="purC"
                     /locus_tag="ACF3UE_000140"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFD3633601.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            31066..31320
                     /gene="purS"
                     /locus_tag="ACF3UE_000141"
     CDS             31066..31320
                     /gene="purS"
                     /locus_tag="ACF3UE_000141"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFD3633602.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            31322..31993
                     /gene="purQ"
                     /locus_tag="ACF3UE_000142"
     CDS             31322..31993
                     /gene="purQ"
                     /locus_tag="ACF3UE_000142"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFD3633603.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31994..34216
                     /gene="purL"
                     /locus_tag="ACF3UE_000143"
     CDS             31994..34216
                     /gene="purL"
                     /locus_tag="ACF3UE_000143"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFD3633604.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            34201..35640
                     /gene="purF"
                     /locus_tag="ACF3UE_000144"
     CDS             34201..35640
                     /gene="purF"
                     /locus_tag="ACF3UE_000144"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFD3633605.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETNFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35663..36715
                     /gene="purM"
                     /locus_tag="ACF3UE_000145"
     CDS             35663..36715
                     /gene="purM"
                     /locus_tag="ACF3UE_000145"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFD3633606.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            36712..37290
                     /gene="purN"
                     /locus_tag="ACF3UE_000146"
     CDS             36712..37290
                     /gene="purN"
                     /locus_tag="ACF3UE_000146"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFD3633607.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            37287..38822
                     /gene="purH"
                     /locus_tag="ACF3UE_000147"
     CDS             37287..38822
                     /gene="purH"
                     /locus_tag="ACF3UE_000147"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFD3633608.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38838..40112
                     /gene="purD"
                     /locus_tag="ACF3UE_000148"
     CDS             38838..40112
                     /gene="purD"
                     /locus_tag="ACF3UE_000148"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFD3633609.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            40234..41148
                     /locus_tag="ACF3UE_000149"
     CDS             40234..41148
                     /locus_tag="ACF3UE_000149"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFD3633610.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(41281..42846)
                     /locus_tag="ACF3UE_000150"
     CDS             complement(41281..42846)
                     /locus_tag="ACF3UE_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3633611.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42839..44290)
                     /locus_tag="ACF3UE_000151"
     CDS             complement(42839..44290)
                     /locus_tag="ACF3UE_000151"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3633612.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIRESKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(44304..45320)
                     /locus_tag="ACF3UE_000152"
     CDS             complement(44304..45320)
                     /locus_tag="ACF3UE_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3633613.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45540..46628
                     /gene="chvE"
                     /locus_tag="ACF3UE_000153"
     CDS             45540..46628
                     /gene="chvE"
                     /locus_tag="ACF3UE_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFD3633614.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46682..48208
                     /gene="mmsA"
                     /locus_tag="ACF3UE_000154"
     CDS             46682..48208
                     /gene="mmsA"
                     /locus_tag="ACF3UE_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD3633615.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            48210..49415
                     /gene="mmsB"
                     /locus_tag="ACF3UE_000155"
     CDS             48210..49415
                     /gene="mmsB"
                     /locus_tag="ACF3UE_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFD3633616.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49672..50649
                     /gene="guaC"
                     /locus_tag="ACF3UE_000156"
     CDS             49672..50649
                     /gene="guaC"
                     /locus_tag="ACF3UE_000156"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFD3633617.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            50913..52337
                     /locus_tag="ACF3UE_000157"
     CDS             50913..52337
                     /locus_tag="ACF3UE_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFD3633618.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(52379..52636)
                     /locus_tag="ACF3UE_000158"
     CDS             complement(52379..52636)
                     /locus_tag="ACF3UE_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633619.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            52798..53907
                     /gene="pdhA"
                     /locus_tag="ACF3UE_000159"
     CDS             52798..53907
                     /gene="pdhA"
                     /locus_tag="ACF3UE_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFD3633620.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            53910..54887
                     /locus_tag="ACF3UE_000160"
     CDS             53910..54887
                     /locus_tag="ACF3UE_000160"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFD3633621.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            54912..56555
                     /locus_tag="ACF3UE_000161"
     CDS             54912..56555
                     /locus_tag="ACF3UE_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFD3633622.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            56563..57969
                     /gene="lpdA"
                     /locus_tag="ACF3UE_000162"
     CDS             56563..57969
                     /gene="lpdA"
                     /locus_tag="ACF3UE_000162"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFD3633623.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            58131..58406
                     /locus_tag="ACF3UE_000163"
     CDS             58131..58406
                     /locus_tag="ACF3UE_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFD3633624.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            58412..59179
                     /locus_tag="ACF3UE_000164"
     CDS             58412..59179
                     /locus_tag="ACF3UE_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFD3633625.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            59347..61176
                     /gene="typA"
                     /locus_tag="ACF3UE_000165"
     CDS             59347..61176
                     /gene="typA"
                     /locus_tag="ACF3UE_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFD3633626.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            61437..63209
                     /gene="recQ"
                     /locus_tag="ACF3UE_000166"
     CDS             61437..63209
                     /gene="recQ"
                     /locus_tag="ACF3UE_000166"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFD3633627.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            63323..63625
                     /locus_tag="ACF3UE_000167"
     CDS             63323..63625
                     /locus_tag="ACF3UE_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFD3633628.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            63628..64791
                     /locus_tag="ACF3UE_000168"
     CDS             63628..64791
                     /locus_tag="ACF3UE_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFD3633629.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            64817..68245
                     /locus_tag="ACF3UE_000169"
     CDS             64817..68245
                     /locus_tag="ACF3UE_000169"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFD3633630.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            68266..69390
                     /locus_tag="ACF3UE_000170"
     CDS             68266..69390
                     /locus_tag="ACF3UE_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFD3633631.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            69371..69817
                     /locus_tag="ACF3UE_000171"
     CDS             69371..69817
                     /locus_tag="ACF3UE_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFD3633632.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            69801..70139
                     /locus_tag="ACF3UE_000172"
     CDS             69801..70139
                     /locus_tag="ACF3UE_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFD3633633.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            70258..70818
                     /gene="rsmD"
                     /locus_tag="ACF3UE_000173"
     CDS             70258..70818
                     /gene="rsmD"
                     /locus_tag="ACF3UE_000173"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFD3633634.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            70815..71306
                     /gene="coaD"
                     /locus_tag="ACF3UE_000174"
     CDS             70815..71306
                     /gene="coaD"
                     /locus_tag="ACF3UE_000174"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFD3633635.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            71296..72339
                     /locus_tag="ACF3UE_000175"
     CDS             71296..72339
                     /locus_tag="ACF3UE_000175"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFD3633636.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            72498..73226
                     /locus_tag="ACF3UE_000176"
     CDS             72498..73226
                     /locus_tag="ACF3UE_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFD3633637.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            73342..73587
                     /locus_tag="ACF3UE_000177"
     CDS             73342..73587
                     /locus_tag="ACF3UE_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFD3633638.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            73584..73802
                     /locus_tag="ACF3UE_000178"
     CDS             73584..73802
                     /locus_tag="ACF3UE_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFD3633639.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            73938..74477
                     /locus_tag="ACF3UE_000179"
     CDS             73938..74477
                     /locus_tag="ACF3UE_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFD3633640.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            74470..76743
                     /locus_tag="ACF3UE_000180"
     CDS             74470..76743
                     /locus_tag="ACF3UE_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFD3633641.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            76781..77827
                     /gene="holA"
                     /locus_tag="ACF3UE_000181"
     CDS             76781..77827
                     /gene="holA"
                     /locus_tag="ACF3UE_000181"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFD3633642.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(77916..78170)
                     /gene="rpsT"
                     /locus_tag="ACF3UE_000182"
     CDS             complement(77916..78170)
                     /gene="rpsT"
                     /locus_tag="ACF3UE_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFD3633643.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(78570..78839)
                     /locus_tag="ACF3UE_000183"
     CDS             complement(78570..78839)
                     /locus_tag="ACF3UE_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633644.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
BASE COUNT        25630 a        13497 c        17199 g        22710 t
ORIGIN      
        1 atgtttttga gaaaataaat gttaaaaatt tattattggt ttgctctata tactgtttaa
       61 taccattgac agtaatgggg gaaaccggtt ggagagcaac caccttgaac tatcagtggc
      121 cagtagcatt tagtttacta actttttatc cgttttttca actcttaaga ggagaagaaa
      181 taaatagaaa aatatattgg gtaagtattc ctttattgat atttttaact aatcaagaac
      241 aagtcaacgc ctgttttttt gttctaacaa gtatagttag tttatatttg attgtcaatg
      301 gacgatataa ttataagtta tcagtatttt caataataag cttagcagaa ttaattttct
      361 ctttgacaac tccagggaat gcattacgtg ctgcacatga aattaataaa tggtttcctg
      421 aatataaaaa tttcaacttt cttaataagt tagatttagg tatttcatca tttggaaagc
      481 cgtttttttt agacatgaat atcttatttt tattgctatt tttcttaatt ttccttctaa
      541 catataggaa atgtcaaaac tattatgtgc gtatattgac tgcattaccg tttttcttaa
      601 acctgattat ttattttggt aatacaatgg gtcaaagctt tacttacgtc aatggaaata
      661 aaagggcaat gatttggagt agtagtaacc tgaataatct ctttacagag ttaggaacga
      721 aactgtcact tttttatcca ggtacttgga tagctacttt agtagtcttg gcattattac
      781 tatgtttaat tgttggaatt tatttaagtt ttgacaataa gaaaacttct atttttttag
      841 ttattttgat gataatggga ttttgttcaa ggttaattat gggattttct cccacagtat
      901 gggcttccgg aatgcggacg tactatatac tttatgttgt tatcgccatc ttagtactaa
      961 tggcagttaa agagctaatg aaaagcatga gtgtacaaaa aaatgaattt atgcaatttg
     1021 gattaaccgt gcttggtatt tgtaccttta taataacggt gataaacaga taatatacaa
     1081 aaaatccctc gctttagtat taggtgaggg attttactcg tttttcgatt aattgtttta
     1141 acacttgcaa gtttctacga gtagcttgtt tccgaccttc atatactcac ctcaggctgt
     1201 ttacatgatt gtacgttctt tttgtaaagg atacagtgat atgtatataa tggcataaag
     1261 aaacgttcaa acaaaaaaac tcgtgaagca aaattaactt cacgagttgt agtgcagatg
     1321 atgggactcg aacccacacg agctaacgct cacatgaccc tcaatcatgc ttgtctgcca
     1381 attccaacac atctgcgtaa taataacaca ctaatgatag cgaggtttta catagttgtc
     1441 aagctcaaaa atgggaggac ttattaagat ggagaaatat gacggagaat tttcaggact
     1501 gggaatgatc ttaggtgtat tgattggact tgcattcgga cgttttttgc ttggttttat
     1561 gctaggaatc atttgtggaa ttgcaatgga ttgggcagcg aatctatgga atgactatca
     1621 tgacaattaa gttctcaacg cttgtttgtg tttttttaat acttacgttt ttcctaaata
     1681 agtggcaaaa ttttctagga tggagtatga tattgaaata gtaaataaca aaaaatttgg
     1741 aaagttctaa ctttttgaaa tgagggattg gctaagtgat gagagaattt gaaaaatcca
     1801 acaaattaga aggtgtcagt tacgatgttc gcggtcccgt tctagaagaa gcggagcgga
     1861 tgcaagaaga gggcattagt attttaaaat tgaacacggg aaatcccgca ccttttggat
     1921 ttgaagcacc aaacgaagtc attcgtgatt tgatcatgaa tgcccgtgac tcagaaggct
     1981 actcagattc caaggggatc ttttctgcta gaaaagcaat tgagcaatat tgccaactga
     2041 aacattttcc gaatgtgacg atcaatgata tctacaccgg caacggagtg agcgaattga
     2101 tcacgatgtg tatgcagggg ttgctggaca atggagatga agtactggtt ccaatgccgg
     2161 actatccgtt gtggacggct tctattgcat tagctggagg cacacctgtt cattatattt
     2221 gcgatgaaga ggcagaatgg tatcctgata ttgatgatat caaatcaaaa ataacgagtc
     2281 ggacaaaagc tattgttatc attaatccta ataatcctac tggggcactt tatccaaaag
     2341 aattattaga agaaatcgtt gaagtagctc gacaaaataa cctgattatt tattccgacg
     2401 aaatctatga tcgcttagtg atggatggtc tagaacatat tccgattgct acattagcgc
     2461 ctgatttgtt cgttgttacg ctgaacggtc tatccaaatc tcatcgtgta gcaggatttc
     2521 gagtaggctg gatggtccta agtggagata agtcacacgt caaaggctat atagaagggc
     2581 tgaatatgtt gtcctccatg cgtttgtgtt ccaatgtatt gtctcagcaa attatccaaa
     2641 ccgcgctagg cggttatcaa agtgtcgatg agctgctcct gccaggcgga aggatctatg
     2701 aacaaagaga atatatctat aatgcaatca atgatattcc tggtctttca gccgtaaaac
     2761 caaaagctgc tttttatata ttcccaaaaa ttgatacaaa gcgattcaat attttggatg
     2821 atgaaaaatt cgttttggac tttttacatg aacatcatat tctacttgta catggtggtg
     2881 gatttaattg gaaccagcca gatcattttc gaatcgttta tcttcctaaa atggatgatt
     2941 tgaaacaaac agctaagaaa atgagagaat tcctagcaac ctatcgccaa aaatgatttt
     3001 aaaaaccaaa tttttcagta ggagggccac agacaaacac actgaggctc tctttctagt
     3061 ggagttttct taaataacta aagtatatta tttagttgca agtcttttct tgaagtttgc
     3121 gacttcctaa agtaaaatac gaatagaatg cgaatacgca tattttgggg aggatactta
     3181 tggaaacgtt aatcgagtcc tttggaacga tcattaaaga gattcgaaaa gaacaaaaaa
     3241 tgacgcaaaa aatgctttcg catgatattt gttcacaaag tgtattaagt cggatcgaaa
     3301 ataatgagga actgccgaat gtattggtga tgatgcagat ttgtcaacgg ctaggggtaa
     3361 cgattgatca tgtgatgaat ctctctcgaa aaactactcg gacaaacgat aaattatttg
     3421 aactgttgga tagttgtttc caaaaacgtg attatcggaa gttagaacaa gtactaaaat
     3481 cttctgatat ttctgaaaat ctgtatcaag caactgactt tcaacgctat tattattatc
     3541 tcggtgtttg cgaattcacg ttgcgtcaaa atatctctca gtccctttat tatttgaaag
     3601 aagcattaag ctactctagc caaaaagaaa gaatccatgt ttctgacaca gaaatacaac
     3661 tgattagttg tatcggaaaa atatatggtg tggcaggaaa aacggctgaa gcacgctact
     3721 atttgagtcg aagcatccaa ctgctgcatc aatcagctga tgaacgatca aaaagtgaat
     3781 tttcgcaaat tttttataat tatggaaatt tcttattcca tcaaaatgaa atcgacgaag
     3841 cgttagaaca ggtgaatcaa ggaatctatt gggctcaaga gaagaatagc tactattacc
     3901 tcaatgattt atttgtgctt aaaagcttaa tatacaagcg taaagaagaa ccagaaagag
     3961 cagcattcta tgaaggctta gcacaagctg tgaaacaaat ttcaaaaaat ttgtaaatgg
     4021 tgtagaccat tcttgacttc ttctctaaat aagagtactt tagaggtaga aaaacaaagg
     4081 gagagaatag aatgagaact tttatctatg ctgacaaatt ctttttagcg tcaggtgtca
     4141 aacatgcagg ctatcttgaa attaccgatg gactttttgg tgaatacacc aaagaactac
     4201 ctgagggaga agtcaacatc attgaccaaa gcggcaaatg gattgctcct ggtttggtag
     4261 atacacatat tcacggctat atgaatcatg atgtaatgga taatgatgca gaaggcatca
     4321 aagtgatgtc tgaaggtctg ttatcttgtg gagtgacttc atttttacca acaacattga
     4381 cgtcaagcaa agaacgttta aaagatgtag ctgagacaat cggcaaaatg tatcaggaag
     4441 caccaggagc taaaatcaaa ggaatctatt ttgaaggtcc tttcttcaca gaagaacaca
     4501 aaggggcaca aaacccaagt tatttcgggg atcctgattt ggatactttc catgaatggc
     4561 aagaagcttc aggtggttta atcaaaaaaa ttgctttagc accggaacgt caaggtgtag
     4621 aagagtttgt caaacaagtg actgaagaag gagtagttgt ttctctagga cacagtaatg
     4681 ctacactaga agaagcgcaa aaagctgttg aagcaggcgc aagtgtattt gtccatgctt
     4741 tcaatggtat gcgtggattg aatcatcgcg aaccaggtat ggtgggtgcg ttattatctt
     4801 tagaacatgt cttttctgaa ttgatttgtg atggccatca tgtacatcca aatgctgcgg
     4861 gaatcctaat ggaaaaagca ggacatgatc atgtcgcatt aattacagac tgtatgatgg
     4921 ccggtgggat gcctgatgga aattacaatt taggcgaatt tccagtagta gtaaaagaag
     4981 gaacagcacg tctagaatct ggcaacttag ctggaagtat attgaaattg aaagaagcaa
     5041 ttaaaaatgt tgtagactgg ggattagcaa caccagaaca agcagtcatg atggctagtc
     5101 tgattccagc aatcagctgt aaaatcgatg atacatgtgg aaaaatcgct caaggacgcg
     5161 atgcagactt tatcgtattg aaccctgata tgacattgga agcaacttat ctagatggcg
     5221 tggaacgttt ccacgcataa tataatttaa gttaacctta aaactaaact tcttaagttt
     5281 ggttttaagg ttttttttgt gttctagtaa aaatcacttt acataagttt caaaagtttc
     5341 tttaatttcc tattgttcaa taagtaacaa tgtaaagata aaattaaaaa tgttaatacg
     5401 tattagcaaa ataaaagctt tttttattgt gaataaatga acataattag gaggagaaag
     5461 atgaacttat ttgacatttt tcgatcgact ttgacagata tgtcgattgt cagtgcaatc
     5521 acttcaacag tttttattat attattaggg tttgtttgta gaaaaaaggg gattttttct
     5581 gaatctgttg gaaaaattct atcgaaagtc gtcttaacag tggctttgcc agcactggca
     5641 tttcgagctt tcatgcaaga tatcaataca gaattactga tgcaaggaat caatgtcttg
     5701 atttggggat tagttattta tattattctt attctagttt caaaaccttt tttcttaagc
     5761 tataaagggg ataagcaaac aacgttgcgt gtcctgacga tctttggttc tacgaccttt
     5821 ttcggaacgc ctatcgtcag tgcgatttat ggtcctgtcg gcgtgatgta ttcctcaatt
     5881 ttcaatattg gctaccgaat ctttttgtat tcttatggat acataaaaat gagtggcttg
     5941 aagatggaag ctaaaaatat caaagcgatg ttcgtcaatc caatcattat cgctactttt
     6001 gccggccttt tcatttggct gttccaaggg tatctgccac aagtgtcagt tacaggtgca
     6061 gaaggagaga taagccaagt agcgtttttg cgaattgacc agactgcacc gtggctattt
     6121 cagccgatgg attatttagc tggtttaagt tcaccattgg cgtggctagc aatcggcgca
     6181 acattaggtg aagtaagctt caaaaaagct gcatctgaaa aaacttcatg gtattacagt
     6241 ctagtcaaag tggtatttgt acctgcattg aatatcgtga ttctagcagt tttgacggca
     6301 acgaatattc taccagtcaa ttttgaagca ctggcaacaa tcgttatcat gatggctaca
     6361 ccagctgcaa cagtggcagc agcctatgct atcagttttg atagggaggc acttttagcc
     6421 tccaatgcat ccttactgtc aactattttt gctgtggtac tgacacctgt atggatcgtt
     6481 gtattacaaa tgattcatgg cataggttta ttttcataag aaatggagga agaaagtatg
     6541 agaatcgcat gttacggtgt tcgtccgaac gagatagatt tttttgaaaa attgaatatt
     6601 taccattatg atctcagtct ttatgaagaa ctgttgacac atgacaatat cgtgtcagca
     6661 aaggaccatg atgctgtatt gttgagggga aattgtatag cagatgagac caatcttgca
     6721 aaaatgcagg aatatgggat tcgttatgtt tttacacgga ctgtgggagt caatcatatc
     6781 gatctacaag cggcagctga ttttggtatg acagtagccc gtgtaccatc gtattcgcca
     6841 aatgcgatag cagagttatc tttgactttt gccatgatgc ttttgagaaa tactgcgtat
     6901 acgacgatcc gaacatcttt caaagatttt cgagtggatg agcaaatgtt tagtcgtgaa
     6961 atcagaaatt gcacagtagg gatcatagga acaggcagga tagggttgac ggaagctgtt
     7021 ttgtttaagg gactaggagc caaagtgatc ggctacgata ttcatcagac agaagctgct
     7081 aaaaaagtat tgacgttcca ctcgcttgaa gagttattag ccaaaagcga tattgtcagt
     7141 attcatgtac ctcatatccc aggtgaaaac gatcaaatga tcaatgaagg atttttagct
     7201 caaatgaaaa aaggtagcat cttgattaat acagcccgtg gagagcttca agataatgaa
     7261 gctattttaa gagctttgaa aagcaatcat ttagctggtt ttgcaaccga tgtttttgca
     7321 aatgaaacag aggttttttt ccgatccttc aagccatggg agacgattcc agaccctgct
     7381 atccagcaat tagtagaaat gtaccctaga gttcttgtaa ccccgcatgt aggttcaaat
     7441 acagatgagg cattatcaaa tatgatttcg acaagtttcg agaactttcg tgaaataata
     7501 gaaactggaa aaacgaaaaa tgaggtatct cttcctaaag cccgtcaatt aagataagaa
     7561 aacatggata ttcgtcaata aaatgtttaa aaatagtcca agtaaacagt tgttacttct
     7621 gtatacttgg actattttgt atgggataat tcgatgactc aacagtaatc tgtgagcttt
     7681 ttccgcccat tctttgtcaa ttcataacag gttagcggcc ggccgatttc caaatatttg
     7741 attctttcgt tcaatatatc ttgttctact aaaaaattca aatatttctt gacggatata
     7801 cgtgacagtg agcttttttg agccagttct tttgttgaaa aaatagtatc ttcttttaga
     7861 ataaatgcac ttattttttt taaagtcagt tttgacagac ctttaggcaa atcgatgaat
     7921 gatggtattt cgtgaatggg agtggtgtgg ttgaatactt gatcgatcaa tttctgatcg
     7981 gctttttcag tcgtttggat tgtctgagag aaagcaagat acttttcgat cgccagctga
     8041 aaacgttgca aagtgaacgg tttgatcaaa taatctaagg caccgtagcg gatcacattc
     8101 tttatggttt cgatatcatc tgcagcagtg atcaaaatca ctgggatatc atttccttgc
     8161 tgtctaagcc aagataaaaa atggatacca ctttcgccag gcatgtatac atcaagcagc
     8221 agcagatctg cgtttttttg tctgaaatat ttttttcctt cttctacatt tctgaaactt
     8281 tcgattacgt tcatattagg gatgctttcc acaaaagtac gattcaattc tgcaaccatt
     8341 ggatcatctt cgattatcag gacatttgtc atcattttga tcttcctttt ttggtaattc
     8401 tagatagacg attgtaccgc catttgtttg tttggaaaat tctaaaaatc caccgtggcg
     8461 tttgacgatt gaatggatga gattcaatcc aaacccacga ttgattccct tcgtcgaaaa
     8521 acctagcgta aatatttttt ctgagatttc ttctgatatc ccgacaccgt catcgcagac
     8581 ggtcacgatg aatacttcag cttctgtgtc atagtttaaa tgaatccgga cctgtccgtt
     8641 tctttcatgt ttttgtagca cggcttcttt tgcattatca agtaagttcc ctaacacttg
     8701 caaaagtgaa tggatggagt catccatctc cattttaggg ataaaagaat cgctttctaa
     8761 cagcatttca acagattgtt ctttggcttc gtttattttg cctaataaaa aaccggcaat
     8821 tgcaggtact ttgatcagac ttgagacttg gccaatctct tttttataat tttgatttag
     8881 ctgctggata aaatgggtga cttcttcata cttcttcaaa tcaatcaaac cagaaatgac
     8941 atgaagttta ttcatgaatt catgggtttg agctctcatg gagtttatat attgtttcgt
     9001 ccccccaagc tcctccatta atttcattac ttctgatcga tttcgtaaag ttgcgactgc
     9061 tcctaaaaaa cggtcattgc taaaaagagg tgtaacgcta gaaatagttt ctatcccatt
     9121 taaatacatg gattgagtcc gaacggtcgt ttgatgctca atcgtctctt taaacaaaac
     9181 gtcatataga ttatcactga tttttttcct acttcgaaat ccaatagctg ctctgtttgg
     9241 tagaaaatgt tttttgcagg tgtattgatc aagaggatag ttttatcaga agagatggct
     9301 aagattcctt catctacttc attttcgata atcgtttttt cacttaactg ttctgctatt
     9361 tcttgtggtt caagtccaag cagtactttt ttcatttttt gggcaagaaa aacggcgcct
     9421 atgatgccta cgctaagtcc aataatcaat gaaaaaacaa tcattttttg tccatctttg
     9481 acttgattgt caatcgtgtt gtttgttaag ccaacacaaa ctgcaccaat aatctcttga
     9541 tcataataaa tagggacgaa atagcggaag ccgaacccta acattccttc tttttcagag
     9601 aaaaattctt gtcctccaat cacttttttc acatcttcat gacttgagaa aggaagaccg
     9661 atgtaacttg ggtctgcgtg agaatatcga atgccttcag ggtccatgac aacgataaaa
     9721 tctaaattcg atgcaatcat gatttcattt gttattcctt gaatcgcatg tgtcgggtca
     9781 ccagtctgca gctttttttg gatgagttta tcattggcaa cgattttagc aatgctagag
     9841 attttatctg acacactaga tcggttcatc gaaagaataa aattcctgat caatatggca
     9901 gaaacaatca aagaaacgaa tgtggagaaa caaacgacaa ggatgatcgt gttctggagc
     9961 tttaatggtt ttttcttaaa aaaaggaaac ataggctacc tcgaaagaat ttattgtgaa
    10021 aattttaaca tgaaaacaaa aatttaacaa attgtcaacg ataaacacaa ccttcctata
    10081 aaaaacacca ctgagtcggt aaaagaagct atacagaatt ttcaaacatt ggtatgatag
    10141 acgtagaaat ggaaggaggc gtgtatatga tagggggaat cgcacttgag acgatttatt
    10201 ggtatacatt gctgatttgt gcaggattgg cagtcctatt gattattttt ggagatgtat
    10261 tcgattttga tggcccgctt gatccgatgc ttattatccc ttggttaact ttcacaagct
    10321 tatttggttt tctaggtgag cgtttaacag atcaatcatc tttattttta tttattgcta
    10381 gtggaggcat atcgatagtg ttggtatttt tgcttaattt ctatatattg atgccgatga
    10441 aacatgccga atcaacgatg tcgtcttctg aaaaaactct ggaaggacaa gtagctgttg
    10501 tgatcacacc gatccctgta cgaggtatgg gagaaattca gttgaaaagt gttaccggtt
    10561 ccattagtcg tccagcttgt ttttacagcc cccaagaaca gacagctgag cggggaacga
    10621 aagtattgat cattgagatc aaggaaagaa tctgttatgt catgccttat gaaagcatga
    10681 taaaagctta aaggagcgtg tgttaaatgg aaataccagt tgtttttatc gcgatcgcaa
    10741 tcgcagcttt gattttactg atgttgctga tcgtctttgt agcgaagtac cagacagcaa
    10801 aaccggatga agcgttgatc atcagtggaa gttatttagg aagcaaaaat gtgcacattg
    10861 atgaaagcaa taacaaaatc aaaattgtgc gtggaggtgg cgcattcgtc ttgccagttt
    10921 ttcaacgttc gaatcggatc agtctattat cgagtaaatt ggacgtctcc acccctgaag
    10981 tgtatacgga acaaggcgta ccggtgatgt gtgatggtac ttcgatcatc aaaatcggtt
    11041 catctgtaga agagattgct acagcagcag aacagttttt aggcaagaca agagaagaac
    11101 tggaaaatga agcaagagaa gtattagaag gacacttgcg ctcgattctt ggttctatga
    11161 ctgtagaaga aatctatcaa aatcgcgata agttcagtca aagcgtacaa gaagtcgctt
    11221 ctgtagacct tgcaaaaatg gggttgatca tcgtttcttt cactatcaaa gaggtcagag
    11281 acaaaaacgg ttatcttgac tctttaggga aaccaagaat cgcccaagtc aaaagagatg
    11341 cagatatagc agaagcggaa gctctaaaag aaacgcgtat caaaaaagct caagcagaaa
    11401 aagaatcaca agcagctgaa ttacagcgac aaacagagat cgcagaatca ttaaaagaaa
    11461 aagaactgaa attagcaacc tacaaacaag aacaagatgt tgctaaagca aaagcagacc
    11521 aagcctacaa tttagaaagt gcccgagcac aacaacaagt aatcgaacag gaaatgcaga
    11581 ttaaaatcgt agaacgtcaa aaacaaatcg aactggaaga aaaagaaatc acacgtcgtg
    11641 aaaagcaata tgattcggaa gtgaagaaaa aagcagatgc cgatcggtac gctaaagaac
    11701 aagaagcaca agctcaaaaa gtcaaagaag tgactgaagc cgaagcagaa cgattccgtg
    11761 tggaagcact ggcagaagcg gaagccaata agacacgttt agctggacaa gcagaagccg
    11821 aagcagcact agcaaaagga aaagcagaag ccgaagcaaa acaaaagatc gccaatgcct
    11881 tcaaggaata tggcgaagca gctgtcttga gtatggttat cgatatgcta ccgcaattga
    11941 tgcgcgaagc agcacagccg ctaggaaata tcgaaaaaat ctctgttgtc gatacaggaa
    12001 gcagttcagg agaaaccagt ggagcgaacc gagtgacaaa ttatgccaca aatttgcttt
    12061 cttctactca agaaacacta aaagcgacaa caggacttga cttgaaggaa atcgtagaga
    12121 atttgtcgac acgtgggact actagccaag taaatatgta tgaagcgcca aaagaggcag
    12181 aacaaaactc gatgaaggaa gaataaagta gtacacttca ccgttcaatc aaaaatggag
    12241 gaagactttt taaagttctt ctctccattt ttttatttta ttgcaaaaga aaattagtcc
    12301 tcgctatttt tcttttgttt ttggatctta gcttctatct cttgtaaatt tgttcttagc
    12361 aatcgttctt tcttttggag ttcgaccaaa tcttctgata gttcttcctt cttttctgtt
    12421 tcaggaggac gaagaaagaa attgataccg attgcaatga atgtccctat aaaagtatct
    12481 agtacacgtt ggatagcata caaagcggat tcgccttgag ggatgctcaa cgcaatcagc
    12541 aacaacgtag ctattgcgga aatgataccg gaattattgt taataccatc tgacacgacg
    12601 atcacaataa taactagaat aggaagcaag atcaattcta ccaaaaaatc attgtgaaaa
    12661 tagcttttga caaaaaaata aatgatagct aatgtaccac ctaatgtatt gccgatgatc
    12721 ctagactttc caaaagaaac ggttgtagtc aagtcctgac gcaaagaaaa aacagcagat
    12781 aatgcagcaa tcatcgggat tcctcgttga gtcaaatgaa aaaacaagat acataaaaaa
    12841 acagctaagg cacttttgat cgtacgcata cctagtcgaa aacggccaaa ttgcatagag
    12901 attctccttt ttggtctttt tactatcata cctaaacttt tgtctgatag ctagtttttc
    12961 attattcaag tataattaaa ataaaaaagg gggaagtaaa tgcgtatagg aatgcgaaca
    13021 gtcaaaacag tgatcagtgt cttcttttcg atggtcacag cgggtagctt atcgctgttg
    13081 tattggccag ctgcagggat cattgcatta ttaagtgtag gaaataccaa gcgctctaca
    13141 ttgcgtacgg gcatgaatcg aatcgcagcc tttatattag ctacggcaac agcactgttc
    13201 agtttttttg ctgttgggta tactattttt ggcttcagtc tttttttatt cctgttcatc
    13261 ccgcttgcct ctcgcttcaa attaaccgaa gggatagtag taaattcggt tttggtcact
    13321 cattatttag tggaggaaaa catgtcttgg cagctgatcg gcaatgaagc gggattaatg
    13381 gcgattggat tagtatttgc tttgcttgca aatgtttaca tgccagatcg tacgaagcag
    13441 ctgaaggaaa accaaataca gatcgaaaaa gaatttcgaa atattttgag acaaatggca
    13501 gaatttcttt tatcagaaaa taaagaagat gtgcagatca aatgcgaaca tttactgaca
    13561 ttcattcgcg aaagccaaga agatgccaga gaacatcaag aaaactactg gctcagacag
    13621 ccgctatact acgaaactta cttctctatg agaagagcac aggccaatgt gattaaagac
    13681 atgctggaaa atctagagag aatccagcaa ccagcttatt atggaaaaca tatctatggt
    13741 ttattgattt atactgcaga aacattttca gagtcaaatg atggcagaca aattttaaca
    13801 cgtattgaag aagtttatgt attgtatcgg caaatgcctc tgccgactag tcgccctgaa
    13861 ttcgaggatc gagcagaatt gttccagttt ttgcagtctt ttaaaagttt tattgaaatc
    13921 aaggcagaat tctcccaaca aaaaatccaa aaatagaggt tgtgaattca gctaatattc
    13981 aggtcaaaaa gctgatttca caacctcttc tttaaacggt gttctcctgt caactcctcg
    14041 gtcacaagtc acaatattca acaaacatga gaagctgttt tttgaaattg ctccttgtga
    14101 ctcggagctg aacggtaggc tcacaacctc tttcttaaac ggtgttcaaa agctttcctc
    14161 tgcggtaata agtccagcca aacgaaaaat aggaggagct atttttgttt ggctgttctt
    14221 attacttgat gcagaacagc tttttcacaa ccttttaaaa ttacatattt ttccatagaa
    14281 cttgcatttg atccaagatt tcgatgacat cttttgtcaa gaagagagag cgattgggca
    14341 agtcaccttc aatcatgtgt accatattct ttatttcgta attcattgct tcagatgtat
    14401 tcccgctttc gatgaattcc tttgtaccat ctgtaaataa gatctccgca cgatcagcac
    14461 gcgggtaatc agcaatcgtc acataaccgt tctcaaaggc aacgataccg acttttggca
    14521 tttttgcctg aaaagtcaag ctgacagcag caagttcatt ttctttgtta cgcaagatag
    14581 tgacggattg ttcgtccacg cctgtttcaa aaggaaccat tgtagaggca actacttcag
    14641 gttgagagct caaaaagaaa cgagcgaaag atacagcata cgtaccgata tccaacagag
    14701 ctcctccagc taattctgga ttgaagaacc ggtttttagg gtctggttct ttgtaactgc
    14761 cgaaaggtgc ttggatcatt tttaaagccc ccagttttcc tgtatccatt attgagcgta
    14821 actgctgata aagtggcatg ttgaagattg tcatcgcttc tgctaagatc aaattctttt
    14881 cttctgctaa gcgcatagcg tcagccagtt cttttttatt tatcgtgatg gctttttcac
    14941 atagaacgtg tttgcctgct tccaatgctg ccaagatatg gtcgatatgc tgtctatttg
    15001 gtacagcaat gtacacgatg tcgatttcag catcgtctaa catttcttga tagcttccgt
    15061 aagcttttgg aatattgtaa cggtgagcga agttttccgc tttttctgaa gttctggaag
    15121 caactgctgt tagttcgctc gtctcttgat tgaagctttc ggcaaactca tgtgcgatgg
    15181 taccaagacc aacgattccc cattgatatt ttttcatctg aaaacgctcc ttcatagttg
    15241 gattgagttt cttgtctgtc tattattata acaaaaatca cgaagaataa agaggagagg
    15301 acttgaaaca ttaaaaaaaa tgaaagcagc gatttaagag gtgctttttg atcaaaactt
    15361 aagtagaata gttaaaagga ggggataaac gtgcatcaag tatatattga tcttattatg
    15421 agtgtattat tagaacagtt tgaaactgaa aaaaattttt tagatgaata cttgctgatc
    15481 agtccagaac aatggcaaaa atggaaagat ggcgagaaaa atctgccatc tgaagcgatg
    15541 cagaaagtaa aaaatctttt cactgattat gaatggatgc taacgcaaaa gattttgcgt
    15601 caaacgatta tttttcccga aaaacgaaac gttgccgttg cagagtacaa gcaaatcaaa
    15661 acacgcatcg cgcaaaaatg gcttagcagc aaagcagcaa aagtcgagct gatccctttg
    15721 aaaaataatc agcaggctgg tagatacctt gacttgaaag taagtattca atatgatgaa
    15781 tggggctatg atgatatttt gaattttcgt ctgccagcag atgttcaaaa acagatcgaa
    15841 ggagaaaaaa tcgaacttct cgattgggtg aatgaaaatc tggaagaaac ttacgttcat
    15901 gaggcgaatg gggaacgtga agaacaacga aaggattttt caagtgaata aatttttagg
    15961 atttggagca gttgtgatta tgatcgcagc aatgggctat gttattttta gcgatgatga
    16021 ttcgcatgtt caagccggca atcaagcagt cgaacgaaca agcaccaaaa caactgctag
    16081 taaagaaaag aacagtcaaa caaccagcag caaggtaaag gacaaagaaa caaaagatcg
    16141 tacgtccaaa caattgccag atgttaaaac agacgattgg aagctagttt tggttggtcc
    16201 agatcacaaa ttagaaaaag aaattgatga gtctactcaa ttggcatcat taagtaacgg
    16261 atacttgatc gacaaacgca ttgctccaga atatgaagca tttgccaagg ctgctgaagc
    16321 agctggattt ccattagtga tggtctcagc ttaccggtct gtatcatccc aacaacaagt
    16381 tttcgaacaa aatgtccaag atgtgatgag tcgtcaaggt gtatcagaag aggaggcgac
    16441 aaagattact aaagaaacga ttacggagcc aggatacagc gaacaccaca caggtctggc
    16501 agtcgatgtc gtcgatcaaa actggtacaa cagttatcct tctactgtat tggatgcaag
    16561 ttacggagat cagcctggag ctaaatggat cgcagataat gctgcgcagt atggatttat
    16621 cgttcgttat ccaaaaggac acgaagatat aactaagatc acatatgaac cttggcactt
    16681 acgttatgtc ggtaaagaaa acgctgagta tatcaccaaa caccaattga cgctagaaga
    16741 atatctgaat gaattaaatg aaaagtagga attgatcatg gcgaaaaaaa agtggaaaaa
    16801 gcaaaagcgc aagaatatcc gttggccagc agtggttgcc ggtgtagcag tgatactctt
    16861 agcctttgtt ttttccttga agaatctgtc ttctcctttt actgataatc agcaagaaaa
    16921 tgaagcgcaa tcccatcagc aatttattga acggcttgtt ccgcatgccc aagaactaca
    16981 agatggttat ggagtgcttc ctagtatcat tttaggacaa gctatattag aatcaaattg
    17041 gggaaaaagt accttggcta gcaaatacaa taatcttttc gggatcaagg cttatgggga
    17101 tcagaagaaa gtaagcctgg aaacaaagga atttgttaac gaagaatgga taactatcca
    17161 aggagacttc aaagtgtatg attcatggga acagtccatg gatgaccata cacaactgtt
    17221 cgtccaagga gtagattgga atcctgcgct gtatgaaaaa gtgattacgg ccaccaacta
    17281 tcaggaagcc gcacaagcat tgcaagatgc aggttatgcg acagaccccg gttatgcgca
    17341 aaaaatcatc caggtcatcg agacgtatca attgaatcag tatgaccgga gatagcaaag
    17401 gagaagtggc tgatggcaga acaatttacg ccagaaatca tgacggaatt gagaaaagat
    17461 atcgtaagag taccggaaat cattttagaa gcaagcggga tcaagatatt tggaaaattg
    17521 atccgttcga tcatctttac tacggatatt gcgatcatac gtaatacaaa tgcgaatgca
    17581 gtaattgctg tgtatccttt tacacctcat ccagcgatta ctaaaagcat tattgaggca
    17641 gctgacattc cagttttctc cggtgtaggt ggtggtttga cacaaggtgc tcgttcttcc
    17701 tacatgagca tgttcgcaga agcgcaaggt tcgttagggg tcgttttgaa cggtcctacg
    17761 cctttagaga cagtaaaaga agtttgtcga gtagttgata ttccagttat cagtacggta
    17821 acgtcgaaat atacagaaat agatgaaaag ttagcagctg gtatttcgat tatcaatatc
    17881 agtgcaggta aagaaactgc agaagcagta cgccattttc gtaaaaaata tcctgaactt
    17941 cctatcattg cgacaggtgg tccaacggaa gaaagtattg ctgagaccat tcaagcagga
    18001 gcaaatgcca tcacatatac gccaccaagt agcggagagc tttttagtcg taaaatggaa
    18061 aaatatcggg aaactgagaa aaagaatcat gaataacagg tgagaatcaa aagacgagga
    18121 agagcagata gtggctcttc ctcgtctttt gtactccagt actatttgtt cagaattcaa
    18181 aaaaaagaga aatttttttg tttttttacc tgtaatgtac ataagaagag ttaaaacctt
    18241 ttgttattat tagcattcta acaaaaaaat gtcttgattt attgaagcgc tttctataga
    18301 atgaaaaacg aataaaaact aaaaaaggca cccgacaatt tagtagcagc taaattgtcg
    18361 gggcttgaaa agtcagcggg aactgaccaa tcaagttgcc atagtcaatg cttgtgcatc
    18421 gacgtgtata ttgtacctaa tttcatacag aattactagt tatttttctg ttttttaggg
    18481 aagagcgcac acgaagaagc atgcttattt agctatgtca aggatattgg gcagttgtct
    18541 gatatccttt tttctttgcg taattatcct cccatcattg aagcaagaag tgtttttagc
    18601 gatgaaagaa gaatcagcac tatctaattt ttcttgaaag tattgagttg ttcatcctag
    18661 gcagaacgat aaggcaagtc ttggttttta ttccccttga aaaagatcgt ttaataaata
    18721 tgttctgtat aaaaatacag tatattgaaa aataacaatg gaagtagagg tgcagagaat
    18781 gaagaaaaga atgagaatca tcttagcttt aagtgttatg ttattcttct tgacggcttg
    18841 tgggcaagaa gatgacaaaa aaatcacgct gaacatggct tggtggggtt cgcaagtccg
    18901 acacgatgca acagtaaaag taatcgagct ttatgaagaa aaaaatcccc atgtgacgat
    18961 cgattatgaa ttttatgatt atgaaggata ttacacaaaa ttaggtacac tagcagcatc
    19021 agatgatatc tgggacattt tccaactgaa caatcaattt cctcaataca tcaatcagat
    19081 tgaaccatta gatgaatatg tggagcaagg gataattgat atttctaatg cagatgaatc
    19141 ctatttagca acgacgactt acgacgggca attagttgga ctgtctaacg gggtgaattc
    19201 gtttgcgatt gcttacaata aaaatatatt tgaacaatta aatatccctg aaccagcttc
    19261 aaattggaca tgggatgaat ttgaacaaat cagctatcaa atcactgaag aattaggaat
    19321 ctatgctatt tcaagattcg aagattttat agctggctgt attattcaaa taccacaagt
    19381 tgagaaagga ttgaattttt ataatcggga agatctatct aacagcttgg gatttgaaaa
    19441 tccagactat ctaacagatt ttttccagct gcgtaaaaat ctggtagaca aaggggccca
    19501 tccagaacca ggtggtggag ctgcaagtac gacggatctg tcttttcagg cggttaggga
    19561 tagagaagcg gcaatggtgt ttctatcaag taaccagttg acagaaatat tgtcaggggc
    19621 tcctgaagat atggagattc agttgattaa tccacctcgc agaaaagcag atggagaatc
    19681 tggtatccct ttacgttctt cgcaaatgct gagtatggca aaaagctcag cccataaaga
    19741 agaagctgct aagtttattg atttctttca aaacagtgaa gaagccaatg aaattttaaa
    19801 aggagaacgt ggtgtaccaa tcatgtcgaa tattcgagaa cagctcgctc gtgcagatga
    19861 tgcaactttg caagcgacat ttgattattt agaaatgatt tccgatatgg acaacggcga
    19921 agtgaatgtc tttgatagtg ctttgaatcc ggaaattcaa gaccaataca atcttttagt
    19981 tgaaaaagtc atttatgaag aagtaacagc agaagaagca gcagagagtc tttatgagtt
    20041 tgcgtcaaac attctaggat agcagcagga ggaaggcatg aaaaaagaaa aactaaaacg
    20101 gttcttggat caagacaatg tggtcggtta cgtatttgct tctccattca tcctaggatt
    20161 tctattgata acagtgatac cgatgatctt gtcactttat tattcgttca ccgattatcg
    20221 tttgggaaat ccagtctcat ggatcggctt ggataattat ataaagatgc tgagtgatgc
    20281 ccgttttttg aactccatcc gagtcacttt tctctatgta tttgcatctg tacctgtgaa
    20341 actgatcttt ggtctattga ttgcttatct tttaacgagg aatatcaaag gaacgacttt
    20401 ctttcgttct ttgtattatg tgcctagttt gatcggtggc agtatttcta tcgctctagt
    20461 ttggcgggag ttgttttcta aaaacgggtt agtgaatatt ttcctggaac gattaggcgc
    20521 acctgcgctt tcctggttta gcgatcaaaa actggtcatg atccctcttg ttttgatgtc
    20581 tgcttggcaa ttcggttcgg caatgatcat ctttgctgca ggtatcaaag agatcccagg
    20641 ctcgtattat gaagcggcag agatcgatgg agcgaacaaa tggcagacgt tttacaagat
    20701 cacgttacct cttctttcgc cgatcatttt gtataacttg gttatgcaga caatcgcggc
    20761 gtttatgact tttacgcagg catttatcat tacccaaggt ggtccgaatg atgccacgaa
    20821 cttttatgct ctttatgtgt ataaccaagc tttttctttt aattctatgg ggtatgctag
    20881 tgctatttcg tggatcatgc tgttgattat gggagctgtc acctttctga ttttcaaatc
    20941 atcaaaaaaa tgggtcgttg tgtgaatgag aggaggaaga aatgaataat acagtaacga
    21001 aatggtttca atacggtttt attttgctat taggtctagt catgatttat ccggtcttat
    21061 ggatgatcgc aggttctttt aaaacggatc aagagattat gagtggttcg ctgaatttga
    21121 ttccagagac ttttcaatgg gaaaattacg caaaaggatg ggcggggttt gctggaattt
    21181 cattttttac tttctttagg aattcgtttg tcatctctgc agtttcgacg atagggacag
    21241 ttctgagctc gacttgtatt gcttacgcat tatcgagaat cgatttcaaa ggaaaaagat
    21301 tctggttcgt cgtcatgtta gtaacgatga tgattcctgc acaagtgatt ttgattccgc
    21361 agtttattat ttacaatcgg ctgaatttgg ttgggacgta tgtgccgctg attttaccac
    21421 atttttttgg acaagcattt ttcatttacc agatcatgca attcatggtc agcatcccca
    21481 aagagttaga tgaatcagcg attattgacg gatgcagcaa gtatagtgtc tttaccaaaa
    21541 ttatttttcc tttgctgaaa ccttcgatca tcacgacgat catcatccag ttttattgga
    21601 aatgggacga cttcatggga ccattgattt atttaaacaa gccgagatct tacacggtat
    21661 cgattgccat caaattattt gcagacgctg gatctagtac gacttacgcg agtatgtttg
    21721 cgatgtctac gttgtcgctg ctaccggttt ttctgatttt cttattcttc aataaatatc
    21781 ttgtccaggg gatcagtaca agcggtctga agggctgaat atgaaaaagc caatagaaga
    21841 gatgtttctt tacaagctca actactatgt ctgtcggatt tttttaacca gtcttatcag
    21901 taatgctctt ttcgctttag ttctaggatg tttgttcact ttaggattag tgctgtctgc
    21961 tcgtgttgtc tatctgattt attttttgat gatgtatcct tcttattatc tatctgtcca
    22021 ttacttggca gaaaaaaagg tatgttggag gaaaggaaaa atcaaacgga tgtgtttcat
    22081 cattacgttg tttcagctgt ttgtcattat ttttgcagtt gattggtatt tattagtggg
    22141 aaagattgga gcttggtatc tgattccttt tctattgtgt ctgttgcttt ttgtatccca
    22201 tagttttttt agtacgctaa ttgatatctg caaagaagat aaagcagata gtcttgttta
    22261 tttgatcaaa aggaatatct ggctgttgtc aaaaaacgtc aaggggtttc tgtggtattt
    22321 atgccttttg tatggactgt tctggtgtat acagcatgat tttttactca ctgcattact
    22381 gtatccaggg ctgccatttg tcacagtatt ttgcttaaaa gaaaaggaga atgactttaa
    22441 atgaagaaaa aatatgtaca agtcggactt ggtgggagag cgcgtttttt ttatgaggca
    22501 attgcctcta cgtatcatca aacttgtgaa ctagtcggtt tttgtgatgt atctcaaaca
    22561 aggatggatt atgcaaatcg gatacttgtg aacaagtatg gacagaaaaa agtaaagaca
    22621 tgtatgccat cacaatttga gcaactactg gatgacgtac ggccggctga agtcattatt
    22681 acgtcagtag atcgaacgca tcatgattat atcattcgtg caatgaaaaa aggatatgat
    22741 gttatttgcg aaaaacctct gactatcgat gaggaaaaag ctcaagaaat aataacggtc
    22801 caaaaacaga cgggaagaag cctgcgagtc acttttaatt atcgttatgc accgtatcac
    22861 acgaagataa aggaactgat agaaagtgat gtgattggta atgtgttttc tatccacttc
    22921 gaatggctgt taaatacgca acacggggca gattatttca gaagatggca tcgaaataag
    22981 cacaatagcg gcgggcttct tgttcataaa tctacccatc attttgatct agtgaatttt
    23041 tggttgaaca gccgtcccca aaaggtattt gcattcggtg gattaaactt ttatgggatg
    23101 cataatgcgg agaaacgcgg agtagaaata ttttacagtc gatgctatgg aagcgaacta
    23161 gctaaagctg atccatttgc tatagacctg tcagccaatg aggaattgcg agaaatgtat
    23221 ttagaagcag aaaaagacag tggatatatt cgtgaccgca gtgtattttc cgatgatatc
    23281 tctattgaag atacactagg cgtaacggtc aaatatgaaa ctggtgcgat tttgacgtat
    23341 tcgctaaacg cgtatatgcc gtgggaagga ttcaatgttt ctttcaatgg cagcaaagga
    23401 cggatcgaaa tgaaagtgat cgaaaagtct tacatcaatg caggtggaga taaaaaggat
    23461 gaaggagcag ccgttcttca gtccatccat gtctatccga tgttcggtga gccatatgag
    23521 gtaatcgtcg aacaagaagc gggcggacat ggcggaggag atccgcgttt attagatgat
    23581 ctatttggtg aagaaaaaga agaagatccg tggaatcggg cagcaactca cgtagatggt
    23641 attttgtcga ttttgacagg aatcgcagca aatcattcta ttgcttcagg aaaagcagta
    23701 gtgattgacg agcttgtcag cttaaaagaa taagaataga tttacggaaa ttacttcccg
    23761 tagtttataa aatcttgcct tattgccgat aggctgtctt ttgaacacta tttattcgga
    23821 aaaaggggct atgacatgct ttttgtcatg ccttcttttt atgtgggctg cttttttaga
    23881 taggagaaaa taaaaataac tatttaaacc cgaacaaaaa ggaataatgc attaaaaatc
    23941 attagatttt acaaaaaaat aagtaaacca cgttgtcagt ttcagaaagt agtgttagac
    24001 tgttttcaat atttgaaaca acatttttta ttcaaatatg gcaaactgcc ttcacgtgca
    24061 aaacagttgc aagaaaatga atttacacta ttattagttt tacataccta cttatatatc
    24121 gtcataatat ggatgacagt ttctagccag taccgtaaat gctggactat aagtaaaaga
    24181 ttggctattt cacccttctt ttcttatgat aaagtggagg gtgtttttct ttaacagaaa
    24241 catagtaggt ttttgcacaa aagcggttat ttcggtatta ataaatgata aaggagcaaa
    24301 taaagtgaaa gaattagttg aacgtattca aaaagacgga cgtatattag gcgagggcgt
    24361 attaaaagtc gacagcttcg tcactcacca agtagaccct gtattgatgg aacaaatggg
    24421 aaaacggttt gcagaagtat ttaaagaaca aggaatcacg aaagttgtga ccattgaagc
    24481 ttctgggatc gcaccagctt tatttgctgc aagagaatta gatgttccaa tgatcttcgc
    24541 tagaaaagca aaaagtttga cgatggatga agaattattg acagcttctg tttattcttt
    24601 tacgaaacaa gtgacaagta cgatttctat ttctcgtaaa tttttatctt cagaagacaa
    24661 agtattgatt atcgacgatt tcttggcaaa cggacaagcg gcaaaaggat tgatcgaatt
    24721 atgccagcaa gctggagcgc aagtagaagg aatcgggatc gtcatcgaaa agtctttcca
    24781 agatggacgt cagttacttg aagaaatggg attgagagtc gtttctcttg cgcgtattgc
    24841 ttccttgacg aatggacaag ttgagtttct tgaggaggac gcataatcgt ggaaaaagaa
    24901 acacaaaatg gaaaagctgc ggttttaggg ctgcagcatc tgctagcgat gtatgcagga
    24961 gcagtagcgg tgcctctttt gatcggtaca ggactaggct ttaatcaaga acagatgact
    25021 tatttgattt caattgatat ctttatgtgt ggattagcga cattattgca attgacagtt
    25081 aaccgatttt tcggaattgg cttgcctgtc gttttaggat gtgcgatcca agcagtagct
    25141 ccactgatct tgatcggaac caatgaagga gtaggagcta tctacggatc tattatcgct
    25201 tctgggatct ttgttgtgtt agtttctggt gtcttttcta aaattaaaaa actattccct
    25261 cctatagtaa caggaacggt tatcaccgtt attggtttga ctttgattcc tgtagcaatc
    25321 gagaaaatgg gtggaggtaa tgcaacagca gctgattttg gtgacaaaac aaatctgcta
    25381 cttgcatttg tgacgattct cctaattgta ggcgtgcaaa tgctggcaaa agggttcatt
    25441 cgttcaatcg cggtattgat tggtttagtc ggaggaagca tcttagctgc tttcatggga
    25501 atgattgatc tgagcgcgat tggagatgcg ccgttgttcc atgttccaca acccttttat
    25561 tttggtaaac caactttcga cgtatggtcg attttactaa tgatcatcat ttccatggtc
    25621 agcatggtag aatcaacagg tgtatatttt gcacttggtg acattactgg gaaaaatgtt
    25681 ggagaagaag aattgaaaaa gggatatcgt gcagaaggac ttgccgttat cttaggcggt
    25741 attttcaata cattccctta tactggcttt tctcaaaatg tcggattggt tcaactttcg
    25801 ggaatcaaaa caagaaaacc catctatttc tctgcattct tcttgattgt tttaggatta
    25861 ttccctaaaa tcggtgcgtt agcacaaatc atccctgagc cggtacttgg tggaggaatg
    25921 ttagtcatgt tcgggatggt ggcagtccaa ggaatccgta tgctgttgga agttgatttc
    25981 agcaatgata aaaatctatt gattgttgct gtttctgttg gatttgggct gggtttcaat
    26041 gttacgccga cattattcag tcaaatgccg caaacattgc aaatgttcac tggaaatggc
    26101 atcgtaatga gtagcattac ggctatcata ttgaatttga tctttaatgg attgaaaaaa
    26161 gatgaagaaa tattggaaga agccttcaag aagtaataga gcaaaagaaa ggttgtgaaa
    26221 tcagcgtttt gacctgattg ttagagaaac aaacggaaaa atagttcctc gtattttgcc
    26281 gtttgtttga gctaataccg agggtcagct gattgaacac cgttgaagga agaggtcgtg
    26341 agcctgccgt tcatctccga gtcacaagga acaatttcaa aaaaaagctt ctcatgtttg
    26401 ttgaatattg ttccttgtga ccgaggagtt ggcaggagaa caccgtttat ccataaaaag
    26461 gaatgtgacc taacttttgt cacattcctt ttttttatct ttaataaaca cgaacaataa
    26521 aatgtttttc tttgttaaca ttcgaaattt ctttgacatc aaaaaaagtg attgttaaaa
    26581 tatgaatgta gaaaaactgg gaggaaaaac aatgacagca aaaatctctg tgattatggg
    26641 gagtacttca gattgggaaa caatgaaaga agcatgtcaa atattggatg aattcggtgt
    26701 gtcttatgaa aaaaaggtcg tttctgctca tcgaacccca gatttgatgt ttgaatatgc
    26761 acaaaacgct cgaaaaaaag gaatcaaaat cattattgca ggagcagggg gagccgcgca
    26821 tctgccgggt atggtcgcat caaaaacaac tttgccggtt atcggtgtac cggtccaatc
    26881 acgaacatta aatggtttgg attcgcttct ttcgattgtc caaatgcctg gaggagtacc
    26941 tgtagctact acagcaatcg gaaaagcggg agcaattaat gctggactac ttgcgataca
    27001 gatgctttcc atgtatgatt tagaattgga ggctaaattg gctgaaagac gttcaatgtt
    27061 ggctaaaact gttatagaaa gtagtgatca acttggttaa acctttgttg cctggttcaa
    27121 cgatcgggat cgtcggtggc ggtcaattag gtcgtatgat ggcgattagt gcaaaagaaa
    27181 tgggctttaa agtaggtgtg ctggatcctg tgagcgattg tccagccgca caagttgcag
    27241 attggcatat tgaaagtgtc tatgatgaca cctttgcgct gaaagagctt gccagaagaa
    27301 cagatgtcat tacctatgaa ttcgaaaacg tcagtgtaga ggcgttaaat gcgattttac
    27361 ccatgtcatt tattcctcaa gggacagact tgcttgcgat tacgcaagac cgcctgttag
    27421 aaaaatcttt tttggaaacg aataacatcg tgattgctcc ttatgcaacg atcgtcagtc
    27481 cgacggatat ccaagatgcg attgacggga tcggctatcc ttgtgttttg aaaaccactc
    27541 gaggcggcta tgatggcaag gggcagtatg ttttgaaaag tcgggcggat ctagctcctg
    27601 ccatggacct tttaagagaa ggaacctgtg ttttagaagc atggatcccg tttgaaaaag
    27661 agatttcgat catggtggca ggaaatggtc aaggagattt cacgactttt ccggtcgtgg
    27721 aaaacatcca ccacaacaat attcttcatg aaacgattgc tccagccgcg attgatcagg
    27781 atgtgatcga ggaggctgag cgtattgccc gtgtgattgc agaagcagtg agcctttcag
    27841 gtgttttagg ggtagaaatg tttttaacaa aaacaggcgg gctatatgtg aatgaattag
    27901 ctcctcgtcc tcacaattct ggacattatt ctattgaagc ttgttctatg agtcagttcg
    27961 atgcccatat tcgaggtatt tgtggttggc cattaggaga aaaagtacgt ttgataagca
    28021 atgcagtaat ggtcaatgtt ttgggagaac aactgctgga aagctatcgc ttgattgaga
    28081 ataagccaga ctggcaattc catttctatg gaaaaaaaca agcaaaaaaa ggtcgcaaga
    28141 tgggacatat cactatcttg acagaagaca tccagcaaac gctggaagaa atcaaacaaa
    28201 cgaatatttg ggattagagg agaaaaaaca tgttagaacg ttatacacgc cctgaaatgg
    28261 ggaatatctg gacggaagag aacaaatacc gtgcgtggct cgaagtcgag attttagcag
    28321 atgaagcttg ggcagaactt ggtgaaatcc cgcaagaaga tgtgaaaaaa attcgtgagc
    28381 atgcatcatt tgatatcgat cggatcttgg aaatcgaaaa attaacacgc catgatgtcg
    28441 ttgcgtttac acgagcggtt tctgaaacat tgggagaaga aagaaaatgg gtccattatg
    28501 gtctaacaag tacggatgtc gtagatactg cttatggcta tctcatcaag caagcaaatg
    28561 atattttacg ggaagacttg aaacgtttta cggaaatcat tggcgaaaaa gcaaaagaac
    28621 acaaatatac agtgatgatg ggtcggacac acggtgtcca tgctgaacca actacttttg
    28681 gattgaaact tgccacatgg tattcagaaa tgaaacggaa catcgaacga tttgaacatg
    28741 cggcaaaagg agtagaagca ggaaaaatct caggagcagt gggaacgttc gcaaatatcc
    28801 cgccatttat tgaagagtat gtatgtaaac aattggggat ccgtccacaa gaaatttcta
    28861 ctcaagttct ccctcgggat ctacatgctg aatatttctc agcgatggcg cttattgcta
    28921 caagtattga acgttttgca acagagatac gcggattgca aaaatccgaa acacgtgaag
    28981 tagaagaatt ttttgcgaaa ggtcaaaaag gttcttctgc tatgccgcac aaaaggaatc
    29041 cgatcggttc agaaaatatg gctggtctag ccagagtggt gcgcggacac atggtcactg
    29101 cctatgaaaa tgtcacatta tggcatgaaa gagatatttc tcattcttca gcagaacgaa
    29161 tcatcttgcc tgataccacg attttattga attacatgtt aaatcgtttt ggcaatatcg
    29221 ttaaaaatct aacggtcttt cctgaaaaca tgaagcggaa tatgtctgca acatttggtt
    29281 tgatttatag ccagcgcgtt atgctgaaat tgatcgataa gggaatgaca agagaagaag
    29341 cttatgatct tgttcagcca aaaactgcgt acgcttggga caaccaagtg cagttccgcc
    29401 cgctgttaga agaagatcca accatcacat cggtattatc taaagaagaa atagacgatg
    29461 cctttgatta tcatcatcat ttgaaaaacg ttgacgtgat attcaaacga gtaggtttgg
    29521 aataaagaag agtgagttgc aaaattcaat taaaatagaa tagcaaaaat aaccaaaaaa
    29581 gaagcagatc cgttagcggt tctgcttctt ttagtttatt atattttctt atcaataata
    29641 ggaacctgat tttaaaagcg gctacctctt taccgtgcct ctttacatac aaaaaataga
    29701 ggaattaagc gtaaatggct tggctattat aactaaaatg ctggttatgg agatgttgca
    29761 gcaagttttc gagaaaagcg tattccatct cttgtccatt gaataagatc tggatacgat
    29821 aatgattttt gaaacgcttc tgttcatgaa tctgactgat tgaaagttcg cctttgtgtt
    29881 ctgtctgata aagaaaagtc cttttacggc attcagcaca gcgtttggtt gctcggcgga
    29941 tttttcggaa tgtataaaaa ctagtatctt tattgcataa ataaacgtct ttgatcgaca
    30001 gcaaatcatt atatagacag gaacgttctt cagctgttaa ttctgataaa aaaagctgac
    30061 cttgttttat tgcatcttcc atcggcaagt gcctcctcga acccattatc caaattttta
    30121 gttaattcta atataccatc attaagtata aatgtaaacg cttgttgatg gtataagatt
    30181 ttcgtttctg ataaaacacg aacattaaaa gaatctaatg ccttaaatgt acatattttt
    30241 gttgatttat aaaaagatga ttgctaaaat ttaaagtgaa aaaacgaaca aaaaacgatg
    30301 tatttgcttt taatgtaaat aaaaaggaga gacgtacatg gagaagaaag aacttttgta
    30361 tgaaggaaaa gccaaaaaaa tatatcttac ttctgatgag aacttgattt ggatagaata
    30421 tttagatcaa gcaactgcgt tgaatggcgc gaggaaagac cagataagtg gaaaaggaga
    30481 attgaataat caaatcacaa gtgcaatttt ccgttatctg actcaaagag gaataaaaaa
    30541 tcattttatt gaacaattgt ctaaaaccga acaattagca aaaaaagtac aaattatccc
    30601 tctggaagtg gttatccgaa atattgcagc aggaagtttc tcaaaacgtc taggtgttcc
    30661 cgaaggtaaa gaattcatca aaccaatcat tgaattctac tataaggatg accagttgga
    30721 tgatccattt atcaatgaag agcatatcta tttcttacaa cttgcaaagc cggaagaaat
    30781 cagtgagctg aaagcccaag cgttggctat taatgaaatt ttgaccgaat tatttgctaa
    30841 ggtcggtttg gttttagtag atttcaagct agaatttggc cggtcgaatg gacaaatttt
    30901 gcttgcggat gaagtaacac cggatacttg ccgattatgg gatgaacgta cgaatgaaca
    30961 tatggacaaa gacgtttacc gcagagatct aggtgatttg atcccagtct atcaagaagt
    31021 atataaccgt ctatcggaac taactgaaga aaaggagcga gtatgatgta tttcgtaaaa
    31081 gtatatgtaa cctataaaga ttcagtgtta gatcctcaag gggaggcagt aaaaaaagca
    31141 gtccatcgta tgggatatga aacaatcgaa gatatccgaa taggaaaata ctttgagata
    31201 caacttgctg atgcagaaga accaatcgat acagtgattg aaacgatttg tgacaagctg
    31261 cttgcaaatg taaatatgga aacataccga tatgaaatca aaaaaatgga ggaagtataa
    31321 catgaaattt gcggtcatcg tttttccagg ttcaaattgt gacgcagata tgttatgggc
    31381 agttcgcgag atcatgggcg ctgatgccga atttgtacgg catgatgagt cctctttaga
    31441 aggatttgat ggggttttac tgccgggagg attctcctat ggtgactatt tgagatgcgg
    31501 tgcgattgct cggttttcta caatcatgga agaagtgatt cgttttgctg aagaagggaa
    31561 accagtattc ggtacatgca atggattcca gatattgaca gaagcaggac ttttgccagg
    31621 tgtactgaga cgaaatgagt ctttgcattt tatttgcaaa actgtaccat tgaaagtcaa
    31681 ccccaagacg gcctttactt cagagtatga agccgacgaa ataatctatc ttccagttgc
    31741 tcatggggaa ggaaattatt tctgtgacga agaaacactt caagaactaa aaaaaaataa
    31801 tcagattgcc tttacttata atgacaacat caacggcagc gtggaaaaca ttgcagggat
    31861 tacgaacaaa gcagggaatg tgttaggaat gatgcctcat ccagaacgtg cagtagaaga
    31921 cttgctagga tcagaagatg ggaaacggtt ctttgcttcc attttaaaaa acttcggaaa
    31981 ggtgaccgta tagatgaaaa cattgaaaga accgacagct gaagagatca agaaaaaaag
    32041 aatctatgcc gaatggggat tgactgatga agaatatcga atgatcgaag aagatatctt
    32101 aggaagaatg cctaattata cggaaactgg actgttttct gttatgtgga gcgaacattg
    32161 ttcctataaa aattctaaac cggttctacg caaatttcct actagtggac ctcatgtgtt
    32221 gcaaggccct ggagaaggcg caggcatcgt cgacatcggt gatggactag cagttgtctt
    32281 caaagcagaa agtcacaatc atccttcagc cgtggagcct tatgaaggag ctgcgacagg
    32341 agttggcgga atcatcagag atattttcag catgggggct cgtccaattg cgttgctaga
    32401 ttcattgagg ttcggcgaat tagataatcc aagaacgaaa tatttactag aagaagtagt
    32461 tgcaggtatc ggcggatacg gcaattgtat cggcataccg actgtaggcg gcgaaattgc
    32521 atttgatcct tgttatgaag gaaacccatt agtcaatgca atgtgcgtag gtttgattga
    32581 acacaaacat atccagaaag ggcaagccgc tggcgtcggt aattcgatca tgtatgtagg
    32641 tgcaaaaaca ggtcgcgacg gtatccacgg agcaactttt gcctcagaag aatttaatca
    32701 agaagaagaa cagcaacgtt ctgctgtaca agtaggcgat ccttttatgg aaaagctgct
    32761 gcttgaagcg tgtttggaat taatcttgca tcattcggat tctctaatag gtatacagga
    32821 tatgggagca gcaggacttg tttcatctag tgcggaaatg gcttcaaaag ctggctcagg
    32881 acttatattg acattagatg aagtcccaca aagagaaact gggatgacac cttatgaaat
    32941 gatgttatcg gaatcacaag aacggatgtt gatttgtgtt aaatcaggag aggaagaaaa
    33001 aatccaagaa ctatttcaga agtatgatct agatgcagtc actatcggta aagtaacaga
    33061 cgacgggcaa tatcggctat atcatcaagg agaagaagta gcaaatctgc cagtcgatgc
    33121 attagctgaa gatgcaccag tttatcataa agaaatgaaa gaaccagctc gaatcgtaga
    33181 atttcagcag ttagctcctt atcagccagt tatcgaagaa cctggacaag tattgcttga
    33241 tctgctgcag caaccgacga ttgcttcaaa acgttcaatc tacgaaactt atgattcaca
    33301 agtacaaacc aatacagttg tccgtccagg aagcgatgct gctgtgatga gggttagagg
    33361 gacgaataaa gcgttagcta tgaccacaga ctgcaacgcg cgctatctgt atttggatcc
    33421 aaaaatcgga ggacaaatag cagtggcaga agctgctaga aatattattg ctagcggtgg
    33481 taagcccttg gcgatcaccg actgcctgaa ctatggttct cctgataaac cagaagtttt
    33541 ttgggaatta tcgacttcag ctgacggaat tgctgctgcg tgtgaaacgt taggaactcc
    33601 tgttatttca ggaaatgtct ctttatataa tgaaacggat ggtcaagcaa tctatccaac
    33661 accaatgatt ggtatggtcg gattgattga ggatcataaa catatcacta ctcaggaatt
    33721 caaaaaatca ggggatctaa tctatatatt aggtaagacg tttgcagatt ttgatggcag
    33781 tgaattacaa aagatgcagc ttggaagaat cgaaggtgtg atccgaaact ttgatctatc
    33841 cattgaaaag agaaaccaag agttagtatt gacagccatc caaaacggat tgattgaaag
    33901 tgctcatgac tgttcagaag gtggcttggc aattgcactg gcagaatcag ctttcaaaca
    33961 tcagctaggg atatctgtac agtttgaatt gtcctctgct caattatttg cagaaactca
    34021 atcaagattt gtgttgacag tcgcaccgga aaataagaca cgattcgaag aaatgatggg
    34081 agatgctgct gttttagcag gtaaggtgac ggatgaagcg ataatcgaaa tttcagcaac
    34141 tgacggtcag atcaaaatag aaactgcagt agcaagaaag tgctgggagg atgcaatcgt
    34201 atgtcttatg aagtgaagag tttaaatgaa gaatgcggga tcttcggtgt ttggggtcat
    34261 ccagacgccg ctagtgtggc atacttcggg ctccatagtc ttcagcatcg aggacaagaa
    34321 ggtgcaggta tcgtgtccaa tgatcgagga aagcttaagg ggcatcgaga tttggggctg
    34381 ctttctgagg tattcaaaga tcaaagaaaa ttgcagcagt taacaggaga agctgcaatc
    34441 ggacatgtac gttatgcaac agcaggcaat ggaagtgtgg acaatattca gccttttcta
    34501 ttcaaatttc atgatcagtc gatcggctta gcgcataatg gtaacttgat caatgctcgt
    34561 tcccttagaa aagagttaga ggaaaatggg gcgatcttcc attctaactc cgatacggag
    34621 atattgatgc atttgatccg acgaagtgaa gaaacaaatt ttttaaataa attaaaaagt
    34681 gctttgaatg aagtcaaagg tggctttgcc tatttattaa tgacagaaac ggcaatgatt
    34741 gccgctttgg acccaaatgg ttttcgtcca ttagcaatcg gacaaatgaa aaacggagca
    34801 tacgtgattg cctcggaaac ttgtgcatta gaagttattg gggcacgttt tataagagat
    34861 gtccagcctg gtgagatagt gatcatcaat gacgaaggaa tccagattga ttgctttacg
    34921 aaggacacgc agctttctat ttgttcgatg gaatatatct attttgccag accagattca
    34981 aacatcgcag ggatcaatgt gcatactgca cggaaaaata tgggacggaa tttagcgaaa
    35041 gaatcgccag taaaagcaga tatggtcgtt ggcgtaccta attcttcttt gtcagccgca
    35101 agcggttatg cggaagctag tggaatccct tatgaaatcg gattagtaaa aaatcaatac
    35161 attgcccgaa catttatcca gccaacgcct gagctaagag agcaaggtgt tcgaatgaaa
    35221 ttatctgctg tacgaggagt agtggaaggt aaaaaggtga ttatggtcga tgattcaatt
    35281 gttcggggta cgacaagcag acggatcgtc catcttttga aagaagcagg ggcaaaagaa
    35341 gtccatgtga ggattgcttc tcctcctttg aaatatccat gtttttacgg gattgatatt
    35401 caaacgcgta aagaactcat tgcggcaaat cacacgattg atgaaatcaa agaatgtatc
    35461 ggtgcagatt ctttaggttt tttaagtgaa gagggtctga tcgaatcgat cggtctggaa
    35521 aaagatgctc cgtattcagg attgtgtatg gcttatttca acggagatta tccgacgccg
    35581 ttatatgact atgaagaaaa atatcaggaa tcactaaaag aaaaagtatc gttcttttaa
    35641 aagcagacca agaagggagt atatgaattc aatggcaaat gcatacgcaa aagctggcgt
    35701 agatgtcgaa gctggatatg aagtagtaga acggatcaag aagcatgtca aaaaaacgga
    35761 acgtttaggt atgatgggcg ctataggagg attcggcggt tgttttgatt tatcggtctt
    35821 tcaattaaaa gagccagtcc ttgtctcggg gaccgatggc gtggggacga aattagcagt
    35881 ggcaatcgaa gcagacaaac acgatacaat cgggatcgac tgcgtagcga tgtgtgtcaa
    35941 tgatatctta gcacaaggcg cagagccgtt atatttctta gactacttag caacggggaa
    36001 aaatgatccg ttacgtttgg aaaatgtagt aaaaggtgta gcagatggat gtgttcaagg
    36061 aaatatggcg ctgattggcg gagaaacagc tgaaatgcct ggtatgtact caggtaatga
    36121 ttatgatcta gccggatttg ctgtagggat agctgaaaaa tctcaattat tgacaggaga
    36181 aacgatcaac ccaggagatg tgttgcttgg aatagcatct agcgggattc attcaaatgg
    36241 gtactctctt gttcgcaaaa ttttctttga gcagcagcag ttttctttat catcaaaact
    36301 gccagaattg aaaaaaacac ttggcgaaga attgcttgag ccaacgaaaa tctatgtttc
    36361 ttccttgctt ccgctgatca aagaaaagaa aataaaagga gctgcacata tcactggtgg
    36421 agggtttgta gaaaatatcc cgcgaatgtt accagaatct atggctgcac aaatcaaact
    36481 tggctcatgg ccgattcttc caatattcgg ctgtttacaa aaatatggtg aaattcctga
    36541 gatggagatg tatgaaatct tcaatatggg catcggtatg gtcctggcag tcgaagaatc
    36601 gaaagtaaaa gaaatagtac acgaaattga gcaagctggc gaaaaagttt atgaaatcgg
    36661 gaaagtgatc gccaaagaaa aacatcgtgt ggtgtttata ggagaagaac gatgagaatc
    36721 gctgtttttg cttctggaaa cggaagcaac tttcaagcgc tagccgatta tctatcgaaa
    36781 aaaggattgg aatcttcgat tgactggttg ttttgtgatc agcctgaagc atatgttttg
    36841 aaacgtgcaa ctgcgttgag tgtaccggca gattgttttt cacctaaaga atttgattca
    36901 aaaaaagagt atgaagaagc aattttgcat aaattgaaag aaaaaaagat cgatttgatc
    36961 gtattagctg gatatatgcg aatcattgga ccggtattgc tgaaaaatta tgataaaaga
    37021 atcatcaata tccatccgtc tcttttacct gccttccctg gtttgcatgg catacgtgat
    37081 gcctttgaag ctggagtaaa agaaacgggt gtcacaattc attatatcga ccaaggtgta
    37141 gatactggac caatcatccg gcaggaaaaa gtgagaattg aacaggagga cacgttcgat
    37201 tctttagaag aaaaaatcca tagagtagag catcgaatct atccagaagt gattagtgaa
    37261 attattgaaa atggaggcta tctgaaatga caagagcatt gatcagtgta tcagataaaa
    37321 ctgggattgt agcattcgcc caaggtttga ttgaacaagg agtagaaatc atttcaacag
    37381 gaggaacaaa gcatgcgttg gataaagctg ggatcaaaac gctttcgatc gaagaagtga
    37441 cagggtttcc tgaaatgatg gatggccgtg tcaaaacact tcatcctaaa atccatggtg
    37501 gtcttttagg aagacgcgat ctccctagcc atatggaggc aatggaaacg gaaaatatcc
    37561 aaccaatcga ctttgtttgt gtcaatttat atcctttcaa agaaacgatt atgaaaccag
    37621 atgtcgaaat agcagaagct attgaaaaca ttgatatcgg tggtcctagt atgctccgta
    37681 gtgcagcaaa aaaccatgaa tttgtcacct ctgttgttga tccatctgac tatgaagaag
    37741 tactttcaga attacgtcag tatgggcata cttcactttc tttcagacaa aaactagcgg
    37801 caaaagtctt tcgtcatact gcggcatatg atgcactgat cgctcaatac ttaacggatt
    37861 gggtggaaga aaaagaaccg gaaaaattga cacttacgta tgaacgaaaa caaacgcttc
    37921 gttacggtga aaatagccat caagccgctg ccttttatca gtccgctctt ctggaaaaat
    37981 attcgatcgc agcagcaaaa caactccatg ggaaagaact ttcttataat aatatccgag
    38041 atgcagatgc tgcgctacgg atcatgaagg aatatgacga gccaacggta gtcgccttga
    38101 aacacatgaa tccttgtggt attgggacag catctacgat tttagaagcg tgggaagcag
    38161 cgtatgaagc agatcctgtt tcaatctttg gtgggatcat cgttttgaat cgagaagtag
    38221 atctgccaac agcagaacag atgcataagc tgtttctaga aatcatcatt gccccttctt
    38281 atacacaaga agctttggaa ttactgcaaa aaaagaaaaa catccgatta ctgacagtag
    38341 actttgcgca ggaagaaaat caaaatcgag aagaaacggt ctcagtctta ggtggacttc
    38401 ttgtacaaga tcaagatctg gcaatagaaa atgaagaaga gtggaaagtc gtgacaaaac
    38461 gtaagccgac tccagcagaa gcaaaagcat tagtgtttgc ttggagagct gtcaaacatg
    38521 tgaaatctaa tgcgatcgta ctggcaaacg aacgtcagac agtaggaatc ggagccgggc
    38581 agatgaatcg agtcggttca gtaaaaattg cgattgaaca agcgcaagag aaaatggaag
    38641 gtgcagtttt agctagcgat gcttattttc caatggatga ttcggttgaa tatgcagcca
    38701 aacatggtat aaaagcaatc attcagccag gaggaagcat caaagaccaa gattctattg
    38761 atatggcgaa taaatacgat ctagcaatgg tctttactga tgttcggcat tttagacatt
    38821 agagaggagt cggataaatg aacattttgg tgatcggtgc aggtggtcgt gaacatgcaa
    38881 taagtaaaaa acttttagcc agtccgaagg tggatacggt gtattgtgcg ccaggaaatc
    38941 cggggatgac aaaagatggt atcaattgtg tcgctatcag tgagcgagat cattcagcgt
    39001 taatccattt tgttaagaaa gaggctattg attggagtat cgttggtcct gaagttcctt
    39061 tgttaaatgg gatcgtcgat gattttatgg cggaaggatt gaaaatcttc ggtccgacaa
    39121 aagcagcagc tctgatcgaa ggttcgaaaa gttttgctaa acaattaatg gatacttatc
    39181 aaatcccgac agctaaatcc agaagttttg aatgttacga aaaagcagca gcgtatatca
    39241 aagaaaatgg tgcgccaatc gtagtgaaag cggacggctt agcagctggg aaaggtgtag
    39301 tcgtggctac cacagtgaag gaagcgctgg atgcggcaga acaaatgttg aaccagcatc
    39361 gatttgggga tagtagcaaa aaaatcgtcg tagaagagtt tttggcagga gaagaattct
    39421 cccttttggc gtttgtccgt aataccaagg tgtatccgat ggtcatttcg caagatcata
    39481 agcgggcatt tgataacgat aaagggccaa atacaggcgg aatgggtgct tattcaccag
    39541 taccgcaaat ttcaaaaaag atgattgaaa aagctgtgga agaagtttta aaaccagcgg
    39601 ctttgggaat gaaagaacta ggacgctctt tcacgggtgt tttatatgcg ggtttgattg
    39661 ctacgaagga aggaccaaaa gtgatcgaat tcaatgcgcg tttcggtgat cctgaaacgc
    39721 aagtcgttct ttctcggttg aagagtgact ttgcgcaagt aatcgatgat ttattagaga
    39781 atcgtacagt agagttaaag tggcagcaag aaggatacaa tgtaggcgtt gtggttgcag
    39841 ctgccggtta ccccgaagaa tatgagacag gaatggttct accagatttt ctggaagaag
    39901 agctttctgt ttactatgct ggagtttcct caaataacgg caaactagtt ggagcaggag
    39961 gacgtcttta tttagtagaa gcatacggtg agacgatcaa agaagcacag aaaaaaattt
    40021 acaccgcgtt aatggataaa acgacagatg gaacatttta tcgtacagat attggagaaa
    40081 aagctgccaa tagcgaactg atcgtgaagt aaatcagctg cttccattta taaaaaatac
    40141 aacaaacata atcggaagcg ccgattttag tgaagccttt tcataaagag tgtggtacac
    40201 ttttgttgtg tatataaata aggaggagtt cagatgaaaa aaattcaatt aggtacttct
    40261 gatcagaaag cagctgcagt gatcttaggc tgtatgcgta tcaacaatgc ggaagatcca
    40321 gtaaaagtga ttgagacagc ttatgaaaac ggcattgatt tttttgacca tgcagatatt
    40381 tatggaaacg gtgaatgtga agaaatcttt gcagatgctc tagcaaaaac atcaatcaaa
    40441 cgagaagatc tttttattca aacaaaatgt ggaatcgttc caggtgtgat gtttgatttt
    40501 tctaaaaaac atatcattga atctgtagaa aaaagtttga cccgtctgaa aatggattat
    40561 gtggatgctt tacttcttca tcgtccagat acattggtag aaccagagga agtagctgaa
    40621 gcgtttgatg aattggaacg gtcaggaaaa gttcgttatt ttggcgtcag caatcaaaaa
    40681 ccaatgcaaa tcgaattgct gaaaaaatat gttcgtcaac cattagtagc taatcagctg
    40741 caatttggct tgaaacatac tggaatgatc gatcaaggga ttcatgtcaa tatgacagat
    40801 gaagcaagta tcgatcatga cggtagtgta cttgattatt cccgattgca tgatatgacg
    40861 atccaagcat ggtcaccata ccagtatgga ttttttgaag gtgtatttat cgggaacgaa
    40921 aaattccctg aattaaacca aacattagaa gaactagcag ctaaatatca aacgacacca
    40981 actggcttgg cttctgcttg gattttacgc catccagcca atatgcaagt gatcgccggt
    41041 acgatgaacg tagggcgaat caaggaaatc gctcaagctt cagaaattaa tatgtctcgg
    41101 gaagattggt acgaattgta ccgtgctgct ggaaacattt taccttaaag attgtcataa
    41161 gcaggtcaaa agggctataa attaaaaaga cagaataact tgaaagctgt tttcagcttc
    41221 gagatattct gtcttttttt attgcaaatg gaaagagtat cattgtacgg atttcgttta
    41281 ttagttattt ttgtttttaa ggaaaagctg tgtccgatat tcttttggag aaatcccttg
    41341 ttttttctta aataaataac tgaaatagtt agggtcatta taaccaattt caaaagcaat
    41401 atctgaaata cgatagtctg attgctgcaa taattttttt gctaattcga ttctttgttc
    41461 tgtcagataa tcgatgaatg tttggttaaa cgattgagaa aaaatcgtac tgaaatgaga
    41521 gggacttaat gcaacttgtt gagcgaccca agttaaggac atatctggat cggtaaaatt
    41581 ttctttgata aaatccaatg catggttcaa aattggctga tatttgttcc ttgaaggctg
    41641 tgagggcaga gcagttaaga aagaaatgaa catataaact gtcgaacggt aaagcgagtc
    41701 gtcggcgctg attgctaagc gttgactggt ggatgtgcaa tgaaccattt cttgcgggat
    41761 tttcttttct ttcaggcaga catgctggag tagcttagtc aagacaaata aacgatataa
    41821 tcgtgttcga gttggtgtgc cttgtggttt cgtcaagtgt tcgatgtact tagatacttc
    41881 gtttttcgat aatgaagaca aatcaagtga gaggtcaaag taaaagacag aatcaactgg
    41941 aagtttcgct tcttgaatca aatcctcata gctgataatt tgttctttaa gggaactggc
    42001 ggtttcaagt atcatctgcg tgatctcaaa agatgcaggt aattcgctga ttctttctgc
    42061 gacaggacca atggcgacag aaaaattatt tttttgtccc ttttctaatt catggaccaa
    42121 cgtttgggct acctgataac tggtctcgat cacattttct tcaagagaat caactattaa
    42181 aaatttgatg aatcgagagg aaacagcaga gaagatcact tgttgattct ccctaaataa
    42241 aaacttcaaa taatcactga gatgagcgta atcttcaaag tctgtactga cttggtttgc
    42301 tgctaataat acggtcattt ttttccctgc taaagagcga ttgaaagatt cagcaagttt
    42361 caatgtttca ctgatcgtaa gtgagccttt gaacaaaccg ttcaagaaat gatttttttt
    42421 caattcgaaa acaagatcag aagaagtgtg cgtttctttt tgctgcaaat ctaaagcagt
    42481 tactgctttt tctattgctt gtttcaattc gctactttta atcggtttaa gcagataatc
    42541 atctgcctgt acctggattg ctcctttcat ataatcgaaa tcgtcgaatc cactaataaa
    42601 tatgagacga gtccaaggaa gtagtttcct tgcttctttt gaaaaagtca acccgtccat
    42661 gaaaggcatt tggatatcag tcagaatgat gtcgggctgt aagtcgataa ttgaagacag
    42721 tgccatctca ccatctccag cttcgccgac ataagtgatt ggataataag aaccaaggac
    42781 agttatttgt tcccgcaagt tattgcgaat gaggtattcg tcttcgatga taaaaacttt
    42841 atacatgttt gtttcctcca attgttttgg gagatagagg gatcatcagt gtgacagttg
    42901 ttccttctcg gtatttgctg tcaatcgtga taggtttttg atcatttccg taataaagaa
    42961 ggagacgctt gtttacgttg taaagtccgt agccgatact gaaatctgaa tcgatccctt
    43021 tggctaactc tttacgtatt tctgccagtt tttctgcagg gatgccaatc ccgttgtcta
    43081 taactttgaa ttggatcatc tcatcaattt tgcatgtggt aatacgaata aatcctttgt
    43141 gacggacgta cttcgttcca tggtatacag cattttcaat caatggctgc aagatcattt
    43201 ttaaaataga aacaggaaaa agtgtttctg gtatatcgat cttatagtca agcatatggc
    43261 cgtatcttat ttttaagatg actagataat cattgatatg gctaatttct ttttcaagag
    43321 gaatccagtc ttgtcctttg cttaaagacg tacgaaaaaa gccggaaagt gcatgggtca
    43381 tagtcagagc ttcttcaaag cagtcttgtt cgatcaaaga aataatggca tccaaactgt
    43441 tataaataaa atggggagta atctgagctt gcaatacacg aacttcactt tgtgctaaat
    43501 ggtattgttt caaagcgttc tcccgtaaag actggtttag atcttccgcc attttattca
    43561 tgctagcggt aagtgtttgt aattccagtg tttccggcag ggttaaacga aagccaaggt
    43621 tccctgaaga aagttgttct gacatctcga tcagctgatt gatcggttct tggacctttc
    43681 tctctaaaaa gcgacgattc tttttcgcat agaaaaaaat ggtactaaga actccaagtt
    43741 ccactattgt taatagaatg agcgagcgga caagtgtcgt attttttttg cttgctaagt
    43801 cgatctccac acgaacaaaa tcttgtaaga tatctgacag cagttgagtg acagaatcta
    43861 cctgattgat gatctcttca ttggtatcca taaaatcttt tgccaagata ttattgatca
    43921 gctcgttttg ataatcttcc agtgtatcga tcgtacgtag cgatacatct aacgtactaa
    43981 tttctttaag tgtatttgta ttatttttgc tctctcgaat atcattccta agttcttcta
    44041 ggatattttc ctcattgaac tcatctacgg ttacttggcc agaaatcaag tcccacatac
    44101 tttccaaaac tttttgatca accttcaaag caattgcatc tgctttttgg atatttgcga
    44161 tcgtctgttg ataaatcaaa agctgttgcg aatataacag tatgctcagt agcaaaggga
    44221 taacagcaaa tagaagcatg gctttgtttg cttgggcaaa aatctgtttt atgcttaaat
    44281 tttttgtcat gatacttctc cagtcaataa tttctggttg ggatgttagc tatattctgc
    44341 tgggaaaaga cagtctcgga aataaaaata tctttaggta atgtttttcc tgtttgaata
    44401 tttccaaaat aacgagtaac ggtattggct acataccagc cgacatcagg tttacactcg
    44461 actacacaat tgacgattcc tgagcgtagc ttctcgatca tatcttcttg tccatcaata
    44521 gttacaatga tcaaatcttc tccaggtttg attgatgttt cttttatcgc agctaaagca
    44581 ccgtgagtca tttcatcact atggctgtat aatacatcga tttcggataa atcatttgtt
    44641 tctaaatatc gtttcatctg gtcttttcct ttcatccgaa taaaatcacc gacaattcgg
    44701 tgaacaatag tcatcggagg tttatggtcg atggttccat ctttttttag ggttggttta
    44761 cgattgattg attccaaaaa tccttcggag cgtagcttgg tcggtgtgga gttctctgaa
    44821 ccagcaagtt ctaggattct gatttcctgt ttctttgaat ttgtgaagtg attgctgaca
    44881 aataaacccg cccgatttcc ttctgctttg aaactggggc caatgtgggt gacgaaaagc
    44941 tcgggatcat tcgtttgaat atgtctgtcg acaagtatga cagggatccc tgctcgcttt
    45001 gcttctttta atacagagtc ccacccggat tcttgcaaag gagtaaaaat gatcatatcc
    45061 actttatagg caatgaacgt ccgtatatct tggatttgcc gttcctgatt catgtagcca
    45121 tttcggtaga gaacttggta atcttctttt tcaagcgcag tgataattga ttcagtatgc
    45181 tttttccgcc agctactctc cgttcctgat tgcgaaaaac caacgactag tgggtcaggt
    45241 gcttcctttg tattaggtgt acaccccatc atttggtaag cgattacaac aagggctaaa
    45301 aaaaataaaa cacgtttcac tttaaatcac tccatctgga tttgttagta ctatcttatc
    45361 agataaaagg gaaaatcaaa gtcaaaagga atcaatcgaa aaaaatccaa gaaacttaaa
    45421 aaaatccaag acaaaaaaag tacacctaaa aaatttaaag taaatcccat aaaaaaatca
    45481 atgttaacgc tttctttatt agctatactc ggtgtatcaa ttgaaatggg ggataaaaaa
    45541 tgaaaaacaa atttagaaag attgttggga ctatcgctat tttgaccgca agcattctat
    45601 taagtgcgtg tggcaattca ggatctgcag atgatagtac ggggtatgta ggaatcgcta
    45661 tgccgaccaa atcagcagaa agatggatcg ctgatgggaa caacatggtc tcggaattag
    45721 aaaaactggg ttataaaaca gatcttcaat atggagaaga taaagtagaa aatcaagtag
    45781 cacaaataga aaatatgatt acaaaagggg tagatacact tgtgattgct tctatcgatg
    45841 gttcggcttt aactgatgtg ttagctaaag caaaagaagc agatatcaag gtgatcgcct
    45901 atgatcgttt actgatgaat tcagaaaatg tcgattatta cgcgactttt gataattttg
    45961 gagtaggtgt atcgcaagca gcttatattg aagagcactt aggattgaaa gaaggaaaag
    46021 gaccattcac gattgaatta tttggtggct cgcctgacga caacaacgca ctaatcaatt
    46081 acaacggagt gatgtctgtt ttacaaccat atatggacaa cggtcagttg gtcgtgccat
    46141 ctggacagac gagtttcagt caaatcgcta cgcttcgctg ggatggttct acggcgcaag
    46201 caaggatgga taatctgtta agcgcaaatt atactgacca aacattggat gctgttttgt
    46261 cgccatatga tccaataagt ttaggaatca tttcgtcatt aaaaggcgtg gggtatggga
    46321 gtgaaagtaa acctttacct gtgattactg gacaagatgc gacagttgct ggcgttaaat
    46381 cgatcattgc cggggaacaa acacaaacga tctttaaaga cacacgtatc ttagcaaaaa
    46441 atacgattga aatgatcaaa gcaatcagtg atggagaaga ggttccggtc aatgatactg
    46501 aaacttatga taatggggtg aaaactgtcc ctacgtattt agcaaataca gtatctgtcg
    46561 ataaagataa ttatcaagca gagctgatcg acaccgatta ttataaagaa tccgatctga
    46621 aaaattaaga ggaaccaaac aaggaactaa agagatctaa gtcagagaga ggataagaat
    46681 tatggcggat tgtattttaa aaatggcaga tatcaccaaa aaattttctg gaatccgagc
    46741 gttagattgc gtgaatctga tgattgaacg tggggaaatc catgcattgt gcggagaaaa
    46801 cggagcggga aaatcaacat tgatgaatgt cttgagcggc ttgtatccat atggctccta
    46861 tgacggggaa atcttttatg atggaaagct gtgtcaattt aaagatttga aagatagtga
    46921 agaaaaaggc atcgtcatca ttcatcaaga attagcacta agtccttatc tttcaataaa
    46981 agagaatatt tttctcggaa atgaacaagc agaaagaggc gtgattgatt gggaactgac
    47041 agaaaagaaa acatatgaac tgctgaataa agtcggtttg tctatcgacc cgaatcttct
    47101 agtatcccag attggcgtag ggcaacagca actagttgaa atagctaaag cattatcaaa
    47161 atccgtccgt ctgttgattt tggatgagcc taccgctgca ttgaatgaag aagaaagcgc
    47221 gaatttgctg agattgatcc gagagttgaa agagcaaggt gtaacctcca tcattatttc
    47281 acataagctg aatgaaatcg tggatatcgc agatcgaatc accattttac gggatggaca
    47341 gacgattgag acactagaaa atgaaatgat cagcgaagag catattattc gcggaatggt
    47401 gggcagagat ttagttgatc gttatcctga aagaaaaccg gatattggag aagtttattt
    47461 taaagtagaa gactggacgg tctatcaccc tcttgatcac gagcgaatca taaacgacca
    47521 catcaacttg catttgaaaa aaggagagat tgtaggaata gctggactga tgggagcggg
    47581 cagaactgaa ttcgctatga gtctatttgg acattcttat ggaagcaaga tatccggacg
    47641 tatattaaag gaaggggcag agatatcagt taagaccgtt ccttcagcca ttgcaaacgg
    47701 actcgcttat gtctcggagg accgaaaatc tttaggactg aatctgctga tggatattcg
    47761 ggaaaacgtg acgctgagca gtttggataa aataagtcaa aaaggagtat tagataaaga
    47821 aaaagaagta actgaggcag aaaatttccg gaaaaagatg cgtataaaaa caaactccat
    47881 ccatcaaatt gtcagtagtc ttagtggtgg gaatcaacaa aaagtcgttt tatccaagtg
    47941 gctgatgaca caacccgata ttcttttttt ggatgagcca acccgtggga tagatgttgg
    48001 ggcaaaatat gagatctaca cgattatcga agaaatggca gcaaatggca aagctgtctg
    48061 tcttatctct tctgaacttc ctgaaatatt agggatgtgt gatcgaatct atacgatgaa
    48121 cgaaggacgt attacaggag aagtctcgcg agaagatgca gatcaggaag tcttgatgaa
    48181 attaatgacg aaagaagagg tgggttaagt tggaacaggc aaaaaatctt acggataaaa
    48241 aagagaaaaa actaaatttg aaaagtagag cagctgatct ttttggtcgc tacagcatgg
    48301 tgatcatttt agcgggacta cttattgcgt ttcaattgat gacggatggt attttctggc
    48361 gtccattgaa tataactaac cttgttctgc aaaatagcca tatattagta ctagctgcag
    48421 ggatgttatt agttgtgctc ttaggtcatg tggatttgtc ggtagggtca gtgatggcgt
    48481 ttgttggtgc aattgcgggc atgatgatgg tcaatcgcca aatgaacccg tggatgacag
    48541 ttatcgcatg tcttgcagta ggcgggctga tcggcgcatg gcaaggtttt tgggtagctt
    48601 atgcagggat accggcgttt atcgtgactt tagcaggatt gctgatgttt cgtggactga
    48661 cacaagttgt tctaggaggc caatctctag caccttttcc agctgttttc caaaaaatgt
    48721 ctacgggtta tttaccagac ttaagcgaag gaagcagcct tcacttcttg acattgattt
    48781 taggaatgat catcacgatc gtgttagttg ttggtcaatg gcgaacaaga aatcgtcgga
    48841 aaaatcattt atttgaagtg gaatctccaa cagctttctt ggtaaaggcg gtatttacag
    48901 cagtcgttgt actaggaata acttatatct ttgcctctta tcaagggtat ccgattattt
    48961 tgatcattct tggtttgatc gttgcagcat atgggttttt gacaaataaa acagtagcag
    49021 gtcgacagat ttatgcgacg ggcggaaatc gaaaagcggc tgaactatca gggatcaaaa
    49081 caaagcgaat cacgttctgg gtattcgtca acatgggagt catggcagct ttagctggat
    49141 tagttttagc tgctcgattg aatgcggcaa cacctcaagc aggtacatcg atggaactgg
    49201 atgcaatggc ggcagtatat tttggtggtg cttcgacttc cggcggcatt ggaacaatca
    49261 tgggtgcgat tgtcggtggc ttggtcatgg gtgtattgaa caatggcatg tcgattttag
    49321 gcgtcggggt agactggcag caggcaatca aaggattgat cttgctttta gccgttgtgc
    49381 tagacttgta taataagaaa aaacgaacaa cgtaggagaa cgccggttat tcagaaaaaa
    49441 gactgtgaca agacatttgt cacagtcttt ttttcgctaa aagcgaacat tcattgtttc
    49501 gtttgtatag actaaaaata atatatgttt ttttaccatt cgtataaatt ctctttttgc
    49561 tcttgatttt tttgcttaat tgagttaaat tacatagggc gctaaaaaaa gccttgatta
    49621 aattaataat gttcgtgttt tgctggatgt gaacatcagg aggataatgt aatgaaagta
    49681 tttgattacg aagatattca attaattcct aataaatgta tcgtaaatag ccgttctgaa
    49741 tgtgatacaa cggtcacatt aggtaaacat acattcaaaa tgccagtagt gcctgccaac
    49801 atgcagacga ttattgatga aacaatcgca gaattcttag cggaaaatgg ttatttctat
    49861 atcatgcatc ggtttgatga agcagctcga attccgttta tcaaaaaaat gaaaaagcgt
    49921 ggattgatta cctcgatcag tgttggcgtc aagaaagagg aatattcctt tatagagaag
    49981 ttggcagaag aatcgctaaa tcctgattat atcactatcg acatcgcgca tggacatgct
    50041 aactcagtta ttgatatgat tcagcatatt aaaaaatatt tgcctgaaac ttttgtgatt
    50101 gccggtaatg ttggtacacc ggaagccgtc cgtgaattgg aaaatgcggg cgcagatgca
    50161 acaaaagtcg ggattggtcc aggaaaagta tgtattacaa aaatcaagac aggctttggg
    50221 actggaggct ggcaactggc agctcttaga tggtgtgcga aagcagctcg caagccgatc
    50281 atcgctgacg gtgggatcag aacacatggc gatattgcaa aatctgtccg ttttggtgcg
    50341 acaatggtca tgattggttc attgtttgcc ggtcacgagg aatctcctgg cgaaacaaaa
    50401 gtcgaaaatg gaatcgtgta taaagaatac tttggttctg cttcagaatt ccaaaaaggc
    50461 gaaaaacgaa atgttgaagg aaagaaaatc tggatccaac acaaaggatc tttgaaagat
    50521 acactagtgg aaatgcaaca agaccttcaa tcatctattt cttatgctgg aggaagagat
    50581 ctggaagcca ttcgaaaagt tgactatgtc atcgtgaaaa attcgatttt taatggagac
    50641 acaatctaaa aaataaataa aatattagga tgttgtgaaa aagttgtcct gcattaagta
    50701 ataagaacag ccaaacaaaa atagttcttt atatgttttg tttggctgga attattatcg
    50761 cagatacaag cttttgaaca tcattattca gaataaggga ctgtgataag atttttgtca
    50821 cagtccctta tgttttgcaa aaaaagtttt tcttttttct cgtaaattcg gtaaaatcaa
    50881 aagaaaaaat agacaataga aaagagaagc ttatgtggga aaaagtagag aaaaaacaag
    50941 gaccgattta tcgtcaaatt atggaacaga ttatgagaga aatcgaaaac ggaaggatca
    51001 atcctggaag tcaacttgaa tcagaacgaa aactagggca actttttggt gtgaatcgtt
    51061 ccaccgttgt ccatgcattg gaagagctta gggagcttgg ggtactaacg agcaaacgtg
    51121 gcagcggatg gtttgttaat cagactgaat gggggaaatt cgctgttcca agaatcgatt
    51181 ggcggcaaat gatctctcct cgttatgagc agacggactg gtatgagcaa aaaataagag
    51241 aagcaaagca gatccaaaaa acatcgtttc ttgatttata cgctagcgag atgccagatg
    51301 agcttttgcc gaattttgag tttccttctt attctcttga agaaatctta gcggaagaaa
    51361 aagaaatgga tcttttaggc tatactccgt tacgtaacaa aatcaaacgg tatttggaaa
    51421 gtaaatttga attggcattt tcccccaacc agcttcttgt gactggtggc ggtcagcaag
    51481 caatcttttt gattttacaa acgattcttt cagctggaga ggggatagct gtagagtcac
    51541 cttctttttt ttaccgatta cctcttttca aagcttcagg aacgcgttta tttgggatac
    51601 cgatggatga agaagggatc gacttagaaa aactgaaaga atcgatccat aaaaataaat
    51661 tgaaagcagt gcttatcaac ccgaattttc aaaaccctac aggaaaagtg atgagtcaaa
    51721 aacgacgaga aaagctagta gaattgtgtc gacagtatcg gcttccaatt attgaagacg
    51781 atgtatttac ggatctttca tttctaaacc aagaagaagt ccttcctata cgaacgattg
    51841 atccggataa tgtgttatac gtcggttcgt tatctagggt tttaggaaaa acaacgaaaa
    51901 tcggttgggt gataggacct gagactttta tctcgcaact agctcaagcg caagaaatga
    51961 tggagttttc gatgaatatc cttacacaaa tcacagtggc taatgtattt aatgaagcaa
    52021 ttgatttgaa aatgcaagat gtaagaaaaa agttgaaaga aaaaagccga ctgataagcg
    52081 cttggggaga ttcacaatcg tttttcaagc ttcattcaat tttaggtggt tactatgcct
    52141 ggattacttg ggatgggaaa aaactagacc ccgaactagc agaaaaagta gtagatatgg
    52201 gtcttggaat tgcaccaagt ctactttttg ggcaagatat aaatggaatc agaatcaatt
    52261 acagtaggct ggatgaaaac caaataccgt tgttttattc aaagatgaaa attctagaaa
    52321 agtggttaac agaataattt cacaaagtaa atagattaaa gaatataaca gcttggattt
    52381 aaatttcaag ctgtttcttt tttttcggaa aaagaatacg atataaagaa actaagaaaa
    52441 aaccattatt tgtacgtccg ttcacgatgt gtaaataaaa taaatgtttg caacaaaact
    52501 gtataacacc aacgttttta aatagaaaca gatggttgta agtttgatta gaaaatagaa
    52561 aaaatgcaga tgaaatataa aacgctttcc ttattgtgat tttattcact aatgctgtta
    52621 atatgcggat tggcataatt tcctttcatc gtgaaaattt gtgcttttag cttgtgtttc
    52681 tcataaatcc atgataattt attaatgaag acggttaaat agtgatacag ttttattcac
    52741 tgtttcaatc gcagaatgaa gagattttct tatagatgag agaggaatgt gtgacaaatg
    52801 gcaaacaaaa aagcaccgat cgacttccaa gcactgctag atgaagtcaa tgcagatttc
    52861 ccagtatatc aagcacttga tcaagatgga aacgtagtta acaaagattt agtacctgat
    52921 ttatccgatg atgaactcgt tgaattaatg actcatatgg tatggtctcg tgtattagac
    52981 caacgttcaa cagcgctgaa ccgccaagga cgcctaggct tttttgcacc aactgctgga
    53041 caagaggcaa gtcagctggc tagtgcttac gcatttgata aagaagatgt tcttcttcca
    53101 ggttatcggg atgtacctca actagtaaaa catggtttac ctttatctca agctttttta
    53161 tggtctcgag gacatgctgc aggtaattct tatccggaag aattgaaagc tctaccacca
    53221 caaattatca tcggtgcaca atatgtacaa gcagccggtg ttgcattagg tttgaagaaa
    53281 cgaaacaaga aaaatgtcgt cttcacttat actggtgatg gcggttcatc acaaggtgat
    53341 ttttacgaag caatcaattt cgctggcgct taccatgcaa atgccgtatt ttatatccaa
    53401 aacaacgggt atgcgatctc tacacctcgt gaaaaacaaa ctgcagcaaa aacacttgca
    53461 caaaaagctg tcgcagctgg gattcctggt attcaagtcg atggaatgga tccgcttgca
    53521 gtatatactg tatctaaaat ggcacgggaa tgggcgatca gtggaaatgg accagtccta
    53581 atcgaaacac tgacttatcg ttatggacca catacactat ctggtgacga tccaacccgc
    53641 taccgtacaa aagacacaga tgacgattgg cagaaaaaag atccattgat ccgcttccgt
    53701 aaatatttga cggaaaaagg actttggtct gaagaaaaag aagaacaagt catcgaagca
    53761 actaaagaag aaatcaaagc agctattgct gaagccgaca aagtaccaaa acaaaaggtt
    53821 tcagatttct tgaaaaacat gttcgaagta tctccacaat caatcaaaga acaaattgca
    53881 atttatgaag cgaaggagtc gaaataatca tggcacaaaa aacaatgatc caagcaatca
    53941 cagatgcctt agcacttgaa ctagaaaatg acgagaatgt cgttgttttt ggtgaagatg
    54001 ttgggaaaaa cggaggagtt ttccgggcaa ctgaaggatt gcaggaaaag ttcggagaag
    54061 accgagtatt cgatactcct ttagctgaat ctggaatcgc aggattgagt ttcggtcttg
    54121 cgttagaagg atttcgtcca gttcctgaaa tccaattctt tggttttatt ttcgaagcaa
    54181 tggacgaagt agtagctcaa atggctcgta caagatatcg aatgagcggc actagaaatc
    54241 tacccatcac aattcgttcg ccatttggtg gcggtgttca tacaccagaa ttgcattcgg
    54301 ataatttaga aggtttgatc gctcagtctc ctggtattcg agtagtgatt ccttccaacc
    54361 cttatgatgc aaaaggacta ttgatttctt ctattagaag taacgatccg gttgttttcc
    54421 tagaacacat gaaactatat cgctcattcc gagaagaagt gccggatgaa gcttacgaag
    54481 ttcctttgga taaagcagca gttactcgtg agggaacaga tgtatctatt atcacatacg
    54541 gagcaatggt gcgtgaagca atcaaagcag cagacaatct tgcaaaagaa aatatatctg
    54601 ttgaaatcat tgatcttcgt acagttgcgc cattagatgt agaaacgatc attcaatccg
    54661 tggaaaaaac tggtcgcgta gttgttgtcc aagaagcaca acgacaagcg ggcgttgccg
    54721 cgcaagtagt ttctgagatc tcagaacgcg ctatcctttc attagaagcc ccaatcggac
    54781 gagtttctgc acctgataca gtcttcccat ttggacaagc agaaaatgtc tggttgccaa
    54841 atgcaaaaga tatcgaagac aaagtaaaag aaatcgcgga attttaagaa aagaagggac
    54901 gaaacaaagt catggcttat caatttaaat tgccggatat cggtgaagga atcgcagaag
    54961 gtgaaatcgt caaatggttc gtcaaaccag gagatacgat caatgaagat gatacattac
    55021 tagaagttca aaatgacaaa tcagtagaag aaatcccgtc acctgttaca ggaacggtta
    55081 aaaatgtgat tgttccagaa ggtaccgtag caaatgttgg ggatgtatta gtagaaatcg
    55141 atgcaccagg acacgaagac aatgaagggg acagtggtgt agccgcagaa tcccaaactc
    55201 cagctaaacc ggctgctgaa cccactgttg atacagaatc agctggatcg tcaagcgaag
    55261 gagtcttcca atttaagtta ccggatatcg gtgaaggaat cgcagaaggt gaaatcgtca
    55321 aatggttcgt caaaccagga gatacgatca atgaagatga tacattacta gaagttcaaa
    55381 atgacaaatc agtagaagaa attccgtcac ctgtcacagg gacagttaaa aacgtgattg
    55441 ttccagaagg cactgtagca aatgttgggg atgtattagt agaaatcgat gctcctggac
    55501 acaatagtgc accgtcaact agtgcgccat cagctgaagc accaaaagaa aaagtggaaa
    55561 catcaggttc agcaagtgtc gttgaagctg ccgatccaaa taaacgtgta ttggctatgc
    55621 catctgttcg tcaatttgcc cgtgaaaaag atgtagatat ctcacaagta actgcaactg
    55681 gaaaaggtgg cagagtaaca aaagaggaca tcgaaaactt cttggcaggt ggtccaagca
    55741 gtgcaccagc gaaatcagaa gcgccagaag cggcagcacc gaaagaagca gctcctgcag
    55801 cagaaagcaa accagctgca ccagcaaaac cattcaagtc caacttagga gacttggaag
    55861 aacgtgtagc aatgacgcca acacgtaaag ctatcgctaa agcaatggtc aacagtaagc
    55921 atacagctcc acacgtgaca ttgcatgatg aagtagaagt gtctaaacta tgggataatc
    55981 ggaaacgatt taaagaagtt gctgctgcaa atggtacgaa acttactttc ttgccatatg
    56041 tcgtgaaagc tttaacagcg actgttaaga aatacccagt attgaatgca tctatcgacg
    56101 atgcaaacca agaaatcgtt tataaacatt actacaatat cggtattgca actgatacgg
    56161 atcacggact atatgtacca aatgtgaaag atgcagaccg caaaggaatg tttgctattg
    56221 cagacgaaat caatgagaaa gcaaaattag ctcatgacgg caaactatct gcagaagata
    56281 tgcgcaatgg aacaattacg atcagcaata tcggatctgt aggtggcggt tggtttacac
    56341 cagtcatcaa ctatccagaa gtagctattt taggtgtagg aacgattgca caacaaccaa
    56401 tcgtaaatgc tgaaggcgaa atcgttgtcg gtcgtgtgat gaaactgtca ttaagtttcg
    56461 atcaccgtat cgtagatgga gcaactgcgc aacaagcaat gaataatatc aaacgtcttt
    56521 tagctgatcc agagctatta atgatggaag gatgataaac aaatggtagt tggagatttt
    56581 gctgtagaat tagatacagt tgtaattggt gcgggacctg gtggctatgt agctgccatc
    56641 cgcgctgctg aaatgggaca aaaagtagca atcattgaaa gagagtatat tggcggtgtt
    56701 tgtttgaatg tcggctgtat tccttcaaaa gcactgatag ctgcaggaca ccattatcaa
    56761 gagtcactag attctgaaat gtttggagta actagtgaaa acgtcaaact agattttgca
    56821 aaaacacaag aatggaaaga aaacaaagtt gtccatacgt tgacttctgg tgttggtttc
    56881 ctattaaaaa aacataaggt tgaaacaatc gaaggagaag cgttcttcgt agatgatcac
    56941 acactacgcg tcattcatcc agattcagct caaacttatt cgttcaataa cgcaatcatc
    57001 gcaacaggtt cccgtccaat cgagattcca ggatttaaat tcggaggacg tgtgttagat
    57061 tctactggcg gattagcatt gaaagaagta cctaagaaat ttgtgatcat cggtggcggt
    57121 gtgattggtg ccgaattggg cggagcgtac gcaaacttag gagcagaagt aacgattctt
    57181 gaaggctcac cacaaatttt accaacttac gaaaaagatc tagtaaaatt agtagaagat
    57241 gatttcaaga aaaaaggcgt aacagtcgta acgaatgcaa tggcgaaaga agcagtcgat
    57301 aacggtgaca gcgtgacagt gaaatatgca gtggacggga aagaagaatc cgttactgct
    57361 gattatgtga tggtcactgt aggtcgtcgt ccgaatacag atgatatggg cttagaacaa
    57421 gcgggtgtcg aagtaggaga acgaggattg atcacggtgg ataaacaagg acgtacgaac
    57481 gtacctaaca tctatgccat cggtgatatc gttccagggg cggcattagc acacaaagcc
    57541 agttatgaag caaaaatcgc tgctgaagca atctctggca aaaaagtagc tgtagattat
    57601 aaagcaatgc cggcagtagc cttcactgat cctgaattgg cttctgtagg tatgacgatc
    57661 aaagaagcaa aagatgctgg tatcgaagca aaagcatata aattcccatt ttcagggaac
    57721 ggtcgggcat tatcgcttgg taaaacagaa ggattcatcc gtctagttac gacgatcgaa
    57781 gataacgtgc ttattggcgc gcaaatcggt ggagtcggcg caagtgatat ggtctctgaa
    57841 ttagctttag caatcgaatc aggaatgaat gctgaagata tcgccttgac gattcatcct
    57901 catccatctc ttggcgaaat cgtcatggat gcttcggaat tagcattagg tttaccaatc
    57961 catatttgat ttgaataata caggcgaaac gcaactgaaa aatcagttgc gttttgtttt
    58021 ttagaattat caataatatt attatgtaaa cttaaaaata tgacaacttc ttggtttatt
    58081 accacttcct atgctacact gaagaggaat atgaaatagg agagttgaag atgcaagaat
    58141 atcagtatcc acttgattta gattggacaa cagacgaaat ggtcattgta atgaagatgt
    58201 gggaagatct ggaacgtgcg aatgaaaaag ggataaacaa tgaagctttt ttgaagactt
    58261 atcagcagtt taaaactgtt gtcaaatcca ttggtgagga aaaacgattg ggacgggaat
    58321 ttgaaaaagc ttccggttat tctttatatc gtacagtgca gcaagcaaaa aaaaatccaa
    58381 acaaaacttt gagaatgaac gggtgagata aatggaacag atgattgatc atatcaagtc
    58441 ctggcttgaa gaagctggtg agaaaatcaa atcttctcaa caaacattaa caatctcgca
    58501 aaaatcaaat cgaacggatc tagtaacaaa tgtcgatcga aacatccaga attttctaat
    58561 cgaaaaaatc cattcctttg atccagaggc gaaaatattg gcagaagaag aagggtgtaa
    58621 tcaattatcg gatctcgatg gaagagtctt tatcatcgat cctattgatg gcaccttgaa
    58681 ttttgtgatt gaaggggaaa atttttgtat tatgctcgct gtttatgaat ccggcgttgg
    58741 aaagcttggt ttcatttatg acgtgatgag aaatgaactt ttttggggtg gaaaaggaat
    58801 aggcgtgtat aaaaatgatg agccattgcc tagaccagca aataaatcct tatcggaagg
    58861 cttacttggt gtgaatagtt atcttttcgg tcataataaa tatggaatcc gagaaattgc
    58921 ggaaagcagc atggggacac gtatgtacgg atgcgctggt cttgaactag tggcaatctt
    58981 gaaaggaaac cacattgctt atatttcaaa ccttagccct tgggattatg cagcgggaaa
    59041 tgtcttattg gaagagtttg gtatggtaac aagcggtctt tttggtactc ctttgacatt
    59101 tgaaaaaagg gaatactatt tagcagggac ttcttgtgca tatgcagaaa tcgcagacct
    59161 tttgaaaaaa gaaggctgaa aaaaaggtag aaatcattca caaaaatgat aaaaacgagc
    59221 aaaagattaa ttttctcgaa aaaatgaaaa cattttacta tatttcatga aaaaagtctg
    59281 ctataattag cagtcgagta aaatttgccc tgtcataaag aaccaataaa aaaggagtta
    59341 gttacattga attatagaaa cgatatccgt aacgtcgcaa ttattgccca cgttgaccac
    59401 ggaaaaacaa cattagttga tgaactatta aaacaatcag atacattaga cgcacatacg
    59461 caattgcaag aacgtgcgat ggactcaaat gcgctagaaa aagaacgtgg tatcacgatt
    59521 ttagccaaaa acacagctgt agactataaa ggtattcgcg taaacatcat ggatactcca
    59581 ggacacgcgg acttcggtgg cgaagtagaa cggatcatga aaatggttga cggcgttgtg
    59641 ttggtcgtag atgcgtatga aggaacaatg cctcaaacac gttttgtatt gaaaaaagca
    59701 ctggaacaac atatcacacc aatcgttgtc gtaaacaaga ttgacaaacc ttctgctcgt
    59761 cctgagcatg tcgtagatga agttcttgaa ctattcatcg aattaggagc agatgatgat
    59821 cagttagact ttcctgtgat ttatgcatct gcactaaatg gtacgtcaag cttgtcagat
    59881 gatccagcag atcaagaacc aaccatggca cctatttttg atacaattat tgaaaaaatc
    59941 cctgctcctg tcgataacag cgacgaacca ttacaattcc aagtttcatt acttgactac
    60001 aacgattatg taggtcgtat cggaatcgga cgtgtattta gaggaacaat caaagtagga
    60061 gaccaagtag cattaattaa attagacgga acagttaaga aattccgtgt aacgaaatta
    60121 tttggtttct ttggactaaa acgtctagag attcaagaag caaaagctgg agacttgatt
    60181 gctgtctcag gtatggaaga tatctttgtc ggtgaaacag ttactcctgt ggatcatcaa
    60241 gatgcgttac ctatccttca cattgacgaa ccaacattgc aaatgacttt cttagttaat
    60301 aattcaccat ttgccggtcg agaaggtaaa ttcgtaaccg ctcgtaagat tgaagaacgt
    60361 ttgatggcag aacttcaaac agatgtatcc ttacgagttg aaccaacaaa ctctccagat
    60421 gcatggacag tttctggtcg tggagaattg catttgtcta tcttgattga aaacatgcgc
    60481 cgtgagggat acgaattgca agtatctcgt ccagaagtta ttgaaaaaga aatcgacggt
    60541 gtaaaatgcg aaccgtttga acgcgtgcaa atcgatacac cagaagaata tatgggtagt
    60601 gttatcgagt ccttgagctt acgtaaaggt gaaatgcaag atatggtcca tacaggaaac
    60661 ggacaaatcc gtttgacatt cttaacacct gcccgcggtt tgattggtta ttcaactgaa
    60721 ttcctttcaa tgacacgtgg ttacggaatc atgaaccata cttttgacca atatctgcca
    60781 atgcttcctg gtcaaattgg cggacgtcac caaggggcgc ttgtttcgat cgatacagga
    60841 aaagcaacga cttattctat catgagtatc gaagaacgcg gtacagtctt cgtagaacca
    60901 ggtacagaag tatatgaagg aatgattatc ggggaaaaca gccgtgataa tgatttgact
    60961 gtcaacatca cgaaagcaaa acaaatgaca aacgtacggt ctgctactaa agaccaaaca
    61021 tctgtcatca aaaaaccaaa acaattgacg ttggaagaat ctttggaatt cttgaatgat
    61081 gatgaatatt gcgaagtaac accagaaagc attcgcttga gaaaacaaat tttagagaaa
    61141 aatgctcgtg aaaaagcatc taaaaagaaa aaataatctg taaaaggatg aagagagaaa
    61201 ccagcttgtt ataaaaaata gctggtttct ttttttgtcc aactcttttc tgtggagaag
    61261 tcatctttgt caatggacat aaattcagaa aatacgccga aagacgttta aaagactttt
    61321 aaaaaactta tttctagaga gtttttgttt cataataaga taatgtttca cgaaaggaga
    61381 tcaacttgtc cttcgaagaa aatcgaagta aaatggcaag agaaaggagc gggaagatga
    61441 acgacttatt aaaacaatac tttggctatg atgagtttag acctggtcaa aaagaaatta
    61501 tccagaaagt cattgatcag gaaaatgtat taggaatcat gcctaccgga agtgggaaat
    61561 caatctgtta ccagcttcca gctttactat tagatgggct tactgtggtt gtgtcccctt
    61621 taatctcttt gatgaaggat caggtggacg cggcgaatca attaggtata cccgccactt
    61681 ttatcaatag ctcgttagat ggttacgaaa cagctagacg cttccaagaa atcgatagac
    61741 agcagtaccg tttactttat atcgctcctg aacgttttat catgccggat tttatccaag
    61801 caatgaagcg atggaacgtc cgtatgatcg ctattgacga ggcacattgt atctctcagt
    61861 gggggcatga tttccgccca agttatttac agatggcgaa ccagctagat caactgccaa
    61921 atcgtcctgt aattgttgct ttgacagcta cagcgactgt gcaagtagct gctgacataa
    61981 aaagactttt aaaaattcca gaaaacaacc atattcagac tggttttgaa cgagaaaatc
    62041 tacgatttca agtaattaaa gatcaaaaaa aagaacaata tctaatcgaa tatttaaaga
    62101 tcaacaaaaa tcaatctggt atcatttatg cagcaacgag aaaagaagta gaccgtctct
    62161 atcatttgct taaaaaattc gatttttccg tgggtagata tcatggtggt ctaaatgaga
    62221 atgagcgaac agaaatgcaa gaagcctttt tatacgatcg cttgcagctg attgtagcga
    62281 caaatgcatt tggtatgggt ataaataaaa gcaatgtccg ttttgttatc cattatcaaa
    62341 ttcctggctc tctagaagca tactatcagg aagctggtcg ggcgggaaga gatggtcttt
    62401 ccagtgaagc catcctgctt ttctctcctc aagatatcca agtccaaaag ttttttatcc
    62461 agcagtccca aagagaagaa gggcaaaagc aaaaagaata tgaaaaatta aaagcgatga
    62521 cagaatacgt gtatattgag tcctgtcttc agcaatacat cctaaactat tttggcgaga
    62581 caagcagtcc gtgcaaccgt tgtggtaact gtttagatga cagagaaata gtagaagtaa
    62641 cgacagaagc acagatggtt ctttcttgct taaaacgtat gggtgagaac tatggtaaac
    62701 aaatgctgat gaaagtctta gcaggatcga aagaacaaaa gctgcaagct ttaggttttg
    62761 gacatttatc tacctatgga ctgatgaaaa accaatcgca aaaagaaacg atgcagttaa
    62821 ttgaatattt gatatcgaat ggctatcttc tgaccatcaa tggtgagtat cctgttttga
    62881 aagtaacaga aagagggata caagtattga aaggacaaga atctgtttat cgaaaggaac
    62941 ccaagaaagt ccagcagcta tcggatgaag aaaccgatac actatttgaa gtgctgcggg
    63001 aactgcgaac ggatctagca tcagaagcag gcgttccccc gtatgtcgta ttttcagatt
    63061 ccacattgaa agaaatgagc cgaatacgtc catcaagcag attggagatg cttcagataa
    63121 aaggagttgg ccaaagcaag cttgataaat atggcgaagc ctttttatct cggataaaaa
    63181 atgcggactc taacgttctg gataagtaga aagaacgaat acgtaaaaat gaataaaaac
    63241 aactggttaa atctgttttt tttgctcctt atgaaaatca aatatgttat aattaaggaa
    63301 ttagaatggg aggtaagcac agatggattc tttgtcgaaa aaacttgcga tccaagtatt
    63361 aaatgatgaa gcagaacgga tcaaacgatt aatccgaaat caaaacaaca gtctctgtat
    63421 ctcacaatgc aaagccttcg aagaagtggt agatacacag atgtacggct tttcccggca
    63481 agtcggtttt gctgtccgta taggagtaat cggaaagaac gagggccagc tgatgttaag
    63541 tgagctagaa cgagaattga atcagttata tagtgaggtt taccaagaaa tttatgataa
    63601 aaaagaagtt ggcaaggagg aatagacttg cctaagaaag tgaaaaaaag gcatctatta
    63661 gactatagca tcttgattcc ctatttaatt ttatgtgtat tgggattgat catggtatat
    63721 agttctacgt cgtatctatt attagaaaac ggacaaaatc cgtccgcatc agtcattaac
    63781 cagagtattt tttgggtgct tagcttgatt gctatcgcac tactttataa aatgaaaaca
    63841 gatgttttga aaaaccagcg tttgatcatg gcagccatcg cagttttgac gattttgctg
    63901 ctgattgttg tgttttttgg taaggagatc aatggggcga aaggttggct gcaaattgca
    63961 ggattctcga tccaacctgc cgaataccta aaaatcattt ctatctggta cctgtctctg
    64021 actttatcta aaagacaaaa cagtgtacaa aaagattttc ttgggactgt gaaacgtcca
    64081 cttgcaatgg ttatcggact tactgcatta gtcgctattc ttcccgattt tggtaatgcg
    64141 gcagttatct ttttgattat tttggttctg cttttagcca gcggagtcaa ttatgtgtat
    64201 actttgattg taggagtagg aggcttttgt ctaagtactt ttacgatctg gctgatcaat
    64261 atcacaaacg gaaagatctt acccggacgt ttacagtata tctataatcg atttgctatt
    64321 taccaaaatc ctttctcaga cgaattaaat aaagggcatc aactagtcaa cggctactat
    64381 gccatgttca acggaggact atttggcagg ggattaggta acagtatcca gaaaaaagga
    64441 tttttacaag aagcacaaac cgattttatt tatgcaatcg tagtggaaga actgggagtg
    64501 attatgggga ttttgatatt agcgttgcta ttctttatga ttgtgcgcat tgtccttgta
    64561 ggtatccgtt caaaagatcc gttcaattcg cttttgtgca ttgggatcgg cgcaatgttt
    64621 ttgatccaag tatttgtcaa tcttggaggg attactggcg ttattccttt gacagggatc
    64681 acgttcccat ttttaagtca aggaggctcc agtttgctga tgctttcgat ttgtgtcggc
    64741 tttgtcctca acatcagtgc ggatgaaaaa cgcaagagct taggtttata ataaaaaaag
    64801 atgtaggagt ggttcgatga aaaaagtttt agttgctaac aggggtgaaa tcgctgtacg
    64861 tgtatttcgt gcttgtacag aattaggaat taaaactgtt ggaatctatg cagaagaaga
    64921 tgaatattcc gtacaccgtt tcaaagcgga tgaagcatat ttagtaggac aaggaaaaaa
    64981 accgattgat gcgtatctag atattgaagg gatcatttct atcgcgaaag aatgcggagc
    65041 tgacgctatt catccgggtt acggtctttt gtcggaaaac ttgaattttg cgcaacggtg
    65101 cgaagaagaa ggcatcattt ttgttggacc caaactgcat catttagata tttttggaga
    65161 taaaatcaaa gcaaaagctg cagctatcga agcggggatt gcttcgattc caggcacaga
    65221 tggaccaatc gcttctatag acgatgcctt ggagtttgcg aaacaatacg gttatccgat
    65281 tatgatcaag gcagctctag gcggcggcgg acgcggcatg cgtgtagctc acgatgaaaa
    65341 gagtgcaaga gagggctacg aacgtgcgaa aagcgaagca aaagcagcct ttggtagtga
    65401 tgaagtgtat gttgaaaaat acatcgctaa tcctaagcat atcgaagtac agattctcgg
    65461 ggatacgcat ggaaacgtca tccatctttt tgaaagagat tgttctgttc agcgccgtca
    65521 ccaaaaagta gtagaagtag cgccttgtgt ctctatgaat gaacagcaac gtcaaaaaat
    65581 ctgccaggca gctgtccaat tgatgaaata tgtcgggtat gtcaacgcag gtacagtaga
    65641 atttcttgtt gaaggagatg atttttactt tatcgaagtc aaccctcgcg tccaagtgga
    65701 acatacgatc acagaaatga ttacagatat tgatatcgta acaacgcaac tgttgattgc
    65761 tcaaggtttg gatctgcata aagaaatcgg attgcctcag caagaaggaa ttaaattaaa
    65821 tggttcagcc attcaatgcc gaatcactac agaagacccg ttgaataact ttttaccaga
    65881 cacagggaaa atcgatacgt atcgttcacc tggtggtttt ggcgtacgtc tggatgtcgg
    65941 aaatgcttac gcgggctatg tagtgacacc gtattttgat tcattgctag taaaagtatg
    66001 tacgcatggt gctacctttg aaacagccat tcagaaaatg gaacgttgct tgaaagaatt
    66061 tagaatccgt ggagtgaaaa caaacattcc atttatgctc aatgtcatca cacatcctga
    66121 attccaatca ggaaatgcaa aaacaacctt cattgatagt acagcaacat tatttgaatt
    66181 tcctcgacta cgagaccgcg gaaacaaaac gatgaaatat atcggtgaaa ttactgtgaa
    66241 tggttttcca ggtatcgaaa gtggcgaaaa accattttat gaagaaccac gtatgcctaa
    66301 agatctaatc acaagaactg attacgtaac ggctaagaat gtattagatg cgaagggtgc
    66361 cgatgctttg gtcgaatgga tcaaaggaca ggaaaatttg ttgttgacgg atacgacatt
    66421 tagagacgcc catcaaagtc tgctagcaac tcgtgttcgg acaaaggatt tcaagcagat
    66481 tgcacgtttg actggagaag gtcttcctga actcttttca agtgagatgt gggggggagc
    66541 aacatttgat gtggcttacc gctttttgaa tgaagatcct tggcaacggt tgagaaaaat
    66601 tcgttcttta atgcctaata cgttgctgca aatgcttttc agaggttcaa atgccgttgg
    66661 gtattctaat tatcctgaca atgtattggt ggaatttgtc aaagaagcag cagcgcaagg
    66721 aatcgatgta tttcgaatct ttgatagttt gaactggact ccacaaatgg aaaaaagtat
    66781 ccaagctgta cgggatactg gtaaaatcgc agaggcagct atttgctata ctggcgatat
    66841 caacgatcca agtcgggcaa aatacaatgt tcagtattat aaagacatgg caaaggaact
    66901 agaacaactg ggtgcgcata tcattgcaat caaagatatg gctgggctgc ttaaaccgca
    66961 ggcagcttat cgtttgatta gtgaattgaa agaaacgaca gatctgccaa tccatctgca
    67021 tactcatgat accagcggga atggaatcat cacttattct gctgcttcaa aagcaggagt
    67081 agacatcgtt gacgtggcaa tgagtgcaat gagtgggaat actagtcagc ctagcatgag
    67141 cagcttgtat tatgcactgg tcaatggtcc acggctgcca gaaatcacga ttgaaaatgc
    67201 acagaaatta aaccattatt gggaagatgt gcgcatgtat tacaaaccgt ttgaaaacgg
    67261 cttgaatgct cctgaaacag aagtatatat gcatgaaatg ccaggaggac agtattcgaa
    67321 tctacagcaa caggcaaaag ctgtcggatt aggtcatcgc tgggatgaaa tcaaacaaat
    67381 gtatcatact gtcaacttga tgtttggcga tatcgttaaa gtaactccat catctaaagt
    67441 agttggagat atggcactat ttatggtcca aaatgatctt acagaagaag atatttatga
    67501 aaaaggcgaa acactaagtt tccctgaatc tgttgtgact ttcttccaag gagaactagg
    67561 gcaacccgtt ggcggatttc ctaaaaaatt gcaaaagatt attcttaaag gcagacctgc
    67621 attgaatgaa cgtccaggtc ttttggctga atcagtcgac ttcaacgaag taaaaaaaga
    67681 attggcagaa aaaattggct atgaaccaaa acaagacgaa gtattaagct atttgatgta
    67741 tccgcaagtc tttttggact atcaaaaagc atataatcaa tttggcgatg ttacattact
    67801 ggacacacca acatttttcc aaggtatacg tttgggtgaa acaatcaatg tacaaatcga
    67861 acgcggaaaa acgcttatca ttcgtttaga tgaaatcgga gaacccgata tcgaagggaa
    67921 tcgcgtactg ttcttcaatt tgaatggaca aagacgtgaa atcactatca aagataattc
    67981 gatcatcagt acggtccaaa cccgattgaa agctgaaccg acaaaccgag aacaaattgg
    68041 agcaacgatg tctggttctg ttttggatgt attagtgaaa aaaggcgata acgttaaaaa
    68101 aggtgatacg ttgatgatta ctgaagcgat gaaaatggaa acggccatcg aagcacgttt
    68161 tgacggagaa gtcgcacatg tatatgtgtc ttcaggagac actatttcgt ctggtgacct
    68221 tttgattgaa gtgactgaga aataataagc gaaaggtggg gaaacatgaa aagactgggt
    68281 ttgttttggc tgattctgct attagttatt gtggcattct acatggaacc agtcttgttt
    68341 ccgccaaaac ttgaagtgaa ggaaaactct gatcaacaaa tatcaaacca aatgacaacg
    68401 tggaaatacc aggagcttaa agcaactggt ttttctactt atatcggaaa accgatcgat
    68461 cagctggaaa aggattttgg ccaagcctat gatcgattaa ctagcggatt tggttttgaa
    68521 acaagatatt atgaaaataa agctagtcat ctcacatttg aagcgaacat ccaagacagc
    68581 agagtcacaa ctgttaaagt actgcaaaca gggcctgctg atatcgcgcc gttttattta
    68641 gggatgacga tgcaagatct tacgaaaatc actactatct atactaattt cacttttgag
    68701 taccatgata cagaagttgg aatcgaacta atggaagagg atatgaatta tcgtccgcta
    68761 attgcttttg ataacgacac ttttgctatt ttattttttg atcaaacaac aaacggccta
    68821 ttttcagttg tgtatttaga taaagatagt cttttgaaac tattgccata tcaagtgttt
    68881 ggtgaaggcc ttccacatta tcaagcagat aaatcggctg attgggaatc aatcaatcgc
    68941 gttaaagaac gaaaaagtac gactttatta aatatgctta gaagagaaga cgaacttccc
    69001 atatacaatc aaacacttgc ctttcaaaac cacagtcagc tgctactaca tgattttttg
    69061 acaaggcctg aggaaatatt gtcagaggaa cgtatggctg attggcaaaa atcgctaggc
    69121 agtgctcaaa cgacagtgaa attctcactg acgaatgatg aattggagaa gttaatcagt
    69181 aaacaaaaat tagaaaatac tagtgggcta tttattcatc cggcgattga cgctactttt
    69241 tcgtttttat attggtacag cgatccttac aaccatgacc gtttcatgga cccgggaacg
    69301 gattctgtag gcattgcttt ttctaaagaa aatatgttag tcttattgca agaagaaaac
    69361 ggagaaagta gtgatagcag tgatcgttaa cgaagagctg tttcaactgg aggatcaatg
    69421 cctccaagtc gctgaaatga taaaaaagag taaaacgatg gcttcttatc ttgaacataa
    69481 acagtcaatg gaagaatctg caaaagtttg ccagttgaaa gaagcgttct tgtctaagaa
    69541 agaagcattt gaaaatgtag cggcatatgg tgagtatgca cctgattatc gtgaaaaaaa
    69601 acgagctgtt cgaaaagcaa aaagacagct tgatatggat gagcatgttg cagctttccg
    69661 atatagtgaa acacagctgc aaagtctgtt ggatcaaatt gtccaagtac ttgccgaaga
    69721 agtttctaat gaaatcaaag tagatgcagg tagcccgttt tttgaaacga aaaaacactt
    69781 tggatgcgga ggtaattgtc atgcaattag acaatagtga atttgaaata acaaaacgac
    69841 gcgggctgat cgtatgggtc tacagcttaa aacaattaaa gaatctgaaa aagttcggct
    69901 tgttgcatta tgtctcaaga agaatgaaat atgtcgtgct ttacttaaat gaagagacat
    69961 tggaagaaac agaagaacga atccgtaaat tacattttgt tcgaaacgta gaacgttctt
    70021 accgaccgga tatcgaaatg aattttgccg aaaaaatagg aaacaaaaca gtattaaaag
    70081 acgaaggttt cgaaattgaa gagctaaata cagaaatccg attagctgaa catctttaaa
    70141 aatctcttat gagcagtttt taaataaaaa ataacttgga taacgatcga tttttgatca
    70201 ttgtccaagt atttttttgg tatactagta ccagtaccat ttctaaggag tgagtagatg
    70261 cggataatat caggaaatta tggcgggcgc cgtttaaaaa gtttagcagg ggcgaacacc
    70321 agaccaacta cagataaagt aaaagaatcc atattcaata tgattggacc atattttgat
    70381 ggagagacag tattggatct gtttgcagga agcggtggtt tagctatcga agcagtatct
    70441 agaggctgca gtcatgcggt atgcgtagac aaaaattacc aagcgctaaa aatcatcaaa
    70501 gaaaacatcg aaattacgaa agaaccagag aaatttacca caataaaact tgatgcggac
    70561 aaagcaatcg aacggctagc agcggagaaa caacaattcg actacttgtt tcttgatccg
    70621 ccatatgcaa aacaaaaaat aatcgatcaa atccataaaa tggaagaact gggacttttt
    70681 tctaaaaccg cagttatcgt atgcgaaacg gataaaacag tcgaattgcc agaaactgtg
    70741 gctggattcc atcaaataag aaaacagatt tatggcataa cggccgtaac tatctataga
    70801 aaagagggaa atcaatgaaa cgtgcattat tcccaggaag ttttgatcct tttacaaaag
    70861 gtcacttaga tacggtggaa cgtgcggcta aattattcga tgaggtagta attggtgttt
    70921 ttatcaatac ttcaaagaaa agtttgtttc ccccagaaga aagaatgaca ttgatcacaa
    70981 aagctgtttc tcatcttcct aatgtaaaag tcatgcatca agaaaatcaa ttgacggtag
    71041 aaacagcaaa agagattggt gcagatgcgt tgatcagagg catacgaagt atcaaagact
    71101 ttgaatatga acgagagatt gctcagatga atcatcatct atatgatgaa ttggaaactg
    71161 tcttcttatt agcaaaacca gaatatagtc acgtgagttc cagtatttta aaagaagtac
    71221 tgcactttgg cggagatgtg agcagctact taccgccagt gatcaacgaa gctttagctg
    71281 gaaagcgtga atcaaatgaa agctaaacaa tggttgaaaa cagtactgat tatcatattt
    71341 ggaatgttga tcattggatt tgtagtagtt cccttgccgt attatgtaga atcaccggga
    71401 gccacgatcg atctgaaaga actaattacg gtcaatgata aggaagataa aggttctggg
    71461 tctttctctc ttacctctgt tggtatcagg caagctacag gtttcttagc tttaaaagct
    71521 aaaatgaccc cttttgaaga attgatcagt gaagaagaat tgactggtgg ggcgacaaat
    71581 gaagaatata atcaaatgca acagtattat atggattctt cccaaaatgc agcaatcgaa
    71641 caagcgttaa aacttgcaga caagccttat aaaatggaat tcaaaggcgt atatgtcatg
    71701 agtgtagaga aaacatcgaa tttctttggc aagctttcag ttggagatac agtaacaaaa
    71761 gtagacggga aaagctttca aagtacagaa gcatttatgg attatgtaaa aagccaaaaa
    71821 gttggacaaa caatcgaaat cagttatttg cataatggtg aagaaaaaac agcttctggt
    71881 gatctgatcg agttaccaac agataaaaag gcaggaatag gtatcacgct tactgaccat
    71941 accgagatcg aatcagatac agatgttcgt attaattctg gctctatcgg tgggccatca
    72001 gcgggattga tgttcacttt agaaatctat gaacaagtca ctggtaaaaa cttgcgacat
    72061 ggtaagcaaa ttgcaggaac tggaacgatc aacagtgaag gagaagttgg ccgaatcgga
    72121 ggaatcgata aaaaagtggc aagtgcggat aaagctggcg tagagatttt ctttgcacca
    72181 gatgatacga tttcagacga tgttaagaaa gaatatcctg aaataaaaac caactacgaa
    72241 gaagcaaaag ctgccgctaa aaaattgaat tcctcaatga aaatcgtacc agtaaaaaca
    72301 gtacaagaag cgcttgacta tctagagaaa atgaaatgaa actaaataat taaagagggg
    72361 ttgtgacacg agttctgtca caacccctct ttttcgtcaa aaatcttcac gataaaaata
    72421 aaaacaaaag aaaaaattga cgtaattaga tgttgaaggg acgattttgc cagagctcac
    72481 tgtttcttca attttaaatg aaaggagtaa tgaatgattt ttactggtca ttctttgaaa
    72541 aaagaacaat gatagaaaaa atcagcaaga aaatactagc ttcacccaaa ttgatcattt
    72601 ggatgtctat gatagttctt atcttttgta tcgcaagtgg ttttttatta tcaaatttgc
    72661 tattttatag agaaacagaa gagactgctg caaaagaaat actttcttcg tttagttcca
    72721 gtggagaaga tccatcagct gaaggaaacg atgtagaaga ggatgctcgt ccaaaggtca
    72781 tgtacaccga tatcaaagga agtgtgaagg agcctggtat ctattccttt tcttcagaag
    72841 aacgggtcta tgatgtacta aagcgtgcag gtggattatt agaagaagcg gatagcgatc
    72901 gaatcaactt ttctgcgaag atagaagatc agcaagtcct atatatccct gctgtaggtg
    72961 aagagctgcc agaacatctt gatcagttgg catcctcgga aggaaaacag cctacagcag
    73021 attccgagcc tcccaaaata aatatcaata cagccactcc atcagaactt cagcagattc
    73081 ctgggatcgg atcagtcaaa gcgcaagaaa tcattcgatt tagagaagaa aacggatcct
    73141 tccagaaagt ggaagacctg caggagattt ctggtatcgg tgaaaagaca gttgaaaaac
    73201 taaaaaactt cgttacaatt aaatagaatg attcaaaatc gactggcacg agcaataaat
    73261 ggacgctaat ggatactaag aataatccaa ttctaagagc ttggcaggac gaggaggtag
    73321 tatttttgga taggaaatag cttgattgtt cgcaaagaaa cattaaaaaa accaatgctg
    73381 aatgtctatc tccaaaataa aatatctggg attcatatta tgaatacggc tgtcagcggc
    73441 aataacagtc aagctctacg agaacgcttt gccaaagatg tacttagcta tacagcagat
    73501 aaagtattta ttctcattgg gacgaatgat ctagcagagc ataaacaact ttctaaagaa
    73561 acgtaccaaa aaatctgcag tggatgatag ttcagctgaa aaaagactat agttctgatc
    73621 atgctttctt tatcacgcca ccagcagtcg atgagacaaa acaaaaatat cggaataaca
    73681 agttgatcaa agaatatatc tctgttctca cagaagtagc aaaacgccat gattgtgaag
    73741 tatcgatttt tatacggaat ttcttgaaca aatggattcg aagaattttt ataatgggct
    73801 aatggatgac ggacttcatt tcggcagtga agggtaggat cttttgtcag acaggatgat
    73861 tcgttatatt taaagaatat tttgtttaag caatgagtac tttttaatca acttgaaaaa
    73921 acggaggaat ataaaacatg ttagaaaaat cttcaaaagc atgcgatacg aataaagaaa
    73981 aagttactga taagtcacat aatgaacgca ttccttggga ccagtacttt atggctcagg
    74041 cagtactgtt atctttacgt agtacgtgta cacgtttaga agtaggagcg acactcgttc
    74101 gagaaaaaag gatcattgct ggcggctata atggagcagt cagtggagat gtccactgca
    74161 tagatgaagg gtgttacgtc gtggatggac actgcttgcg aacgatccat gcagagatga
    74221 atgcactcct acagtgtgca aaacttggta tcccgacgga aggttcagaa atctatgtca
    74281 cacattttcc atgtttggcc tgtacaaagg ctttgttgca agctggtgtg aaagggatca
    74341 attatctcca tgactatcga aatgatcctt atgcccaagc gttgatcgaa caattaggtg
    74401 tatctgtaca ccaagttgct ttagactcac agcatttttc aaaacttcaa aatgaattaa
    74461 caggaaaaca tgtctagcgt tttagaaagg catgttcgaa atcggttgat ttttccggca
    74521 attacgtcga tgattatctg tttgttgtat tacactgaca attggggtta tcgtttgctt
    74581 cttgccggaa tttttttatg gttttcgcta aaagaaggac gttttatcgc gtacttgtgt
    74641 attttgtgta gcataacggt atccatttct tataggctac aagagtattc atttttagag
    74701 gaaaaaacaa catctgcgca aattactgta tttacagata cgattcgtgc aaatggtaat
    74761 tttttgacaa tggaaggaag gttatcagag aataaacaaa agctccagct ttcttatcaa
    74821 gtaaacacag aagcagaatt gaaaacatgg cttaacttcc gaggaaaggg aatagaattg
    74881 actgctgaag gcgagttcat ctctccagca aaaaagcgga atctttataa ttttgaccaa
    74941 gaagcttact tcaggaacca tagaatttct ggacggttcc aaattcaaaa gattgaacag
    75001 atcaccatgc aaaatcactg gcgaaactgg cttcagagaa aaagaggatc ttttatctcc
    75061 tttgtccaat ctgaatttcc gcaaaaaaca agtgtatata ttaattcttt attatggggc
    75121 tataaagatg caggattcag agaaccagaa gaaattttta gggagagtgg tttgctgcat
    75181 ctgttcagtc tatcgggtct acacatccaa ttttatttag ggtggctgta ttatttattt
    75241 cgacgtatcg gatggccact acacgtcagt attattccgt tgagtctact aactatctgt
    75301 tatgtttcta ttgcaggaag ttctatttct gttttgcgtg ctagtttgct gtttttattg
    75361 cgattgctag tcaaattgct gaataagcat tattccacca tggacttatt tgcagttgtc
    75421 ttttggcttc ttttactatt tgatcctcga tttctttttc atgcgggtgg acagcttagt
    75481 tttttcatga gttttttgtt tatcctgatt tcttttgatg gagattggtt gaaaaaaacg
    75541 gcctctcacg tcctgtttac tatgatcacg atgccgttga ttgtatggca tttttatgag
    75601 tggcctattt taggtagtct ttttacatta ctgattgcac cggtattcaa gtttcttttt
    75661 cttcctggtg tgttatttct cacactcttc aatcgctggc tgccggaaac tttacttttg
    75721 ctgatagaag agggattaat cttatttgag cgaataatcg atttttcttc agggtcgtct
    75781 ctcattatag gacgtttgcc ccttgtgcta tctgggatgt atattttcgg attactgatt
    75841 tgtatggata ggttgaaaga acaacctgtg aaacacttgt tttatgttgg tcttttttct
    75901 tttatttttt tgactttgcc atttttacgc ttttcttcaa cgatcgcttt tatcgatgtc
    75961 ggtcaaggag acagtatctt tttgcaaagt ccttttcgaa aagaaacgat tttgatcgat
    76021 actggaggtc agttacactt tgaaagagaa aagtgggcgc aaggtatgat acgtcctcct
    76081 gctgaaagaa atatcgttcc atatctaaaa ggtcagggga taagtgtaat cgataaactc
    76141 atcttgacac acgacgatac ggatcatgtg ggagaattac ccacgttatc tcagcatttt
    76201 actatcaaaa aaatttatat cggttggggc gctggacgaa atgagccatt acaaaggcat
    76261 ttatctgaag ctcaaaaaaa tggtactgag atcattgaaa tcaaacatgg ggacaggatc
    76321 agcggttatt atgatcttta tgtattgact ccttttgaaa agggagaggg aagaaatgaa
    76381 gattcgattg gtctatggat ggaatataac aataggcgct ttttattttt aggagatttg
    76441 aatcaagcaa tggaaaaaca attgcttttg atttatccta atctgaaagc cgatgtagtc
    76501 aaattaggtc atcacggtag ccgtacgtca agtaacacag attttctttc ccatattgaa
    76561 gcaaaacatg ggattatatc ctgcggcgta aataatcgtt atggtcaccc gcacagcgaa
    76621 gtattggaga cactagaaga aaatcagata aaaacatggc gaacggatca acaaggaatg
    76681 atcacctatc gctggcatcc agtttttcat cctcatgggc tagtggaaac aatgatagac
    76741 tagtaattct catctgctca tggtaggata atttttgaaa gtggtgagta atttgagtat
    76801 acaagcagag ttacaaaaaa tacgtaaaga aaaacttgca tcttgttact tgattttagg
    76861 aacagaaaag tttctccaag atcaagttcg gacagaaatt gtcaaaaaaa tccaattaga
    76921 gggcgaagat gacttaaatt ttttaagttt tgacatggaa aatgcaagtt tagatgaggt
    76981 agtagctgaa gcagagacgt tgccgttttt cggagatcaa cggttagtat tcgtagagaa
    77041 tccttatttt ttaacaggtg aaaaagtaaa caatggaatc gaacaaaata ctgatttatt
    77101 gacggcttat ttgaaagaac cattagaatc gactgtatta gtattctttg cgccatatga
    77161 aaagttggat gaacggaaaa aagtaacgaa acaattgaaa aaaacagcaa ttatcatcaa
    77221 tgtccaacag ttgaatgaaa aagaagtacg tcaatatctg atgaatacct tagagaattc
    77281 ctcaatcaaa atggaacgaa gtgcaattga tttattcttg aggttgaccg acttagattt
    77341 atccaaaatg atgagagagt tacagaaatt ggtcctttat ggacaaaatc aacagcaaat
    77401 cacggtaaga gaagtagaag aattagttcc taaaacgtta gaacataata tttttgacat
    77461 gacccaatat attttaaaag ggaagacgga acaagctttg cgtttatacg aagatttagt
    77521 tatgcaaggg gaagaaacaa tcaaaattaa tgcgattttg ctttctcaat tacgtttatt
    77581 tttacagaca aaatttcttg taaagattgg ttatcagcag gcaaatattg ctgaaacatt
    77641 gaaaatccat ccatatcgtg taaaacttgc catgcaggaa gtaaaaaaat tcgatgaaca
    77701 tttgctggta cagttgtttg atcaattagt tgagatggat tatcaaatca aaacgggaca
    77761 aatcgaaaaa gaattaagtt ttcaactatt cgttttgcgc acagggcagt tgttaagaaa
    77821 tcgataagaa gaaagacgag ggcaaagcat gcgggaaggt cgtttgtttt tgtccttttt
    77881 ttgacaaata aaaaaatcgg ccgaagccga ttcttttatt tagcgatttt tttgcttaaa
    77941 cgagatttgt cgcggttagc tttgtttttg tggattagac cttttgattc agccatatca
    78001 atagctttaa cagcttcttt atataacgca tctacgttgt cagcacctga agctacagca
    78061 tcttcaaatt ttttgattgc agtacgcata gcgcttgttt gagatgaatt tttcacatta
    78121 gcgttttcgc ttgtacgaac acgtttgatt gcagattcaa tgtttggcat tagtttcacc
    78181 tccgataact taagttctta cgcgtgttac cgcataattc aacattcatt attataccta
    78241 aaggcagcgt gctttgcaat atgaacatga caagtttttt tccttaacag tcttttatta
    78301 ggattttttt tcagtaaaaa cggatagtac aagctgaaaa aaatcaaaaa gacgctattg
    78361 tgggaggcaa tagcgtcaaa ccaaactaga tttttattta tctatttaaa caaagtttga
    78421 atgggaatgt ttggtactaa gttattatat aacaaagaga accgtttgca aagttttttt
    78481 tgaaaaggga tacgattccc tgttgttctt tgtttttcta ttaagaaact gcagttattt
    78541 tataaccagt atcctttgat cagtaaaggc tattctggtg taccgattat tttaatgtat
    78601 tcatcgatat tttttatcaa catttttttt atgaccaact ggttccgacg gttccatttg
    78661 ccacttactt ccagcacata tttatttagg ggcaaacgta agatatattt tgccaaatag
    78721 cgatctttaa gcaggccatt gatcacacgg tcctcaagct gcaagttgat cccagtcagc
    78781 atcattggct gttcttgtaa aacgtacgta tcaattaaaa gaccttcaaa agtttccaca
    78841 agcgtcttcc tttcttttca aagtaacctg aaaacaggca ctaattcttc cattttgata
    78901 ttcgttgaag tggatgcgat cattctttct tttgtccact gtaatctagt ataacaaaaa
    78961 agagcagaag agccaaaaag aaaaaagagc atcgaattct ataggaagtc tcattggcac
    79021 ggcctaaatt attaca
//
LOCUS       DAXLPC010000003        78480 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.003, whole genome shotgun sequence.
ACCESSION   DAXLPC010000003 DAXLPC010000000
VERSION     DAXLPC010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 78480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.003"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            312..683
                     /locus_tag="ACF3UE_000184"
     CDS             312..683
                     /locus_tag="ACF3UE_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFD3633645.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(957..1649)
                     /locus_tag="ACF3UE_000185"
     CDS             complement(957..1649)
                     /locus_tag="ACF3UE_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3633646.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(1652..2437)
                     /locus_tag="ACF3UE_000186"
     CDS             complement(1652..2437)
                     /locus_tag="ACF3UE_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3633647.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            2674..4074
                     /gene="lacG"
                     /locus_tag="ACF3UE_000187"
     CDS             2674..4074
                     /gene="lacG"
                     /locus_tag="ACF3UE_000187"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFD3633648.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            4099..4416
                     /locus_tag="ACF3UE_000188"
     CDS             4099..4416
                     /locus_tag="ACF3UE_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD3633649.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            4429..6102
                     /locus_tag="ACF3UE_000189"
     CDS             4429..6102
                     /locus_tag="ACF3UE_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFD3633650.1"
                     /translation="MDGIIKQIEKGKAFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            6116..7747
                     /locus_tag="ACF3UE_000190"
     CDS             6116..7747
                     /locus_tag="ACF3UE_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFD3633651.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(8238..9803)
                     /gene="guaA"
                     /locus_tag="ACF3UE_000191"
     CDS             complement(8238..9803)
                     /gene="guaA"
                     /locus_tag="ACF3UE_000191"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFD3633652.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(9862..10785)
                     /gene="coaA"
                     /locus_tag="ACF3UE_000192"
     CDS             complement(9862..10785)
                     /gene="coaA"
                     /locus_tag="ACF3UE_000192"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFD3633653.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            10981..11586
                     /locus_tag="ACF3UE_000193"
     CDS             10981..11586
                     /locus_tag="ACF3UE_000193"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3633654.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            11894..12910
                     /locus_tag="ACF3UE_000194"
     CDS             11894..12910
                     /locus_tag="ACF3UE_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3633655.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13051..14352
                     /locus_tag="ACF3UE_000195"
     CDS             13051..14352
                     /locus_tag="ACF3UE_000195"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFD3633656.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14398..15060
                     /gene="deoC"
                     /locus_tag="ACF3UE_000196"
     CDS             14398..15060
                     /gene="deoC"
                     /locus_tag="ACF3UE_000196"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFD3633657.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            15081..15479
                     /locus_tag="ACF3UE_000197"
     CDS             15081..15479
                     /locus_tag="ACF3UE_000197"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFD3633658.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15545..16627
                     /locus_tag="ACF3UE_000198"
     CDS             15545..16627
                     /locus_tag="ACF3UE_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3633659.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            16839..18401
                     /locus_tag="ACF3UE_000199"
     CDS             16839..18401
                     /locus_tag="ACF3UE_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3633660.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18394..19527
                     /locus_tag="ACF3UE_000200"
     CDS             18394..19527
                     /locus_tag="ACF3UE_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3633661.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19527..20483
                     /locus_tag="ACF3UE_000201"
     CDS             19527..20483
                     /locus_tag="ACF3UE_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3633662.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20582..21748
                     /gene="deoB"
                     /locus_tag="ACF3UE_000202"
     CDS             20582..21748
                     /gene="deoB"
                     /locus_tag="ACF3UE_000202"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFD3633663.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            21772..22590
                     /locus_tag="ACF3UE_000203"
     CDS             21772..22590
                     /locus_tag="ACF3UE_000203"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFD3633664.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22607..23314
                     /gene="deoD"
                     /locus_tag="ACF3UE_000204"
     CDS             22607..23314
                     /gene="deoD"
                     /locus_tag="ACF3UE_000204"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFD3633665.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(23612..24298)
                     /gene="gpmA"
                     /locus_tag="ACF3UE_000205"
     CDS             complement(23612..24298)
                     /gene="gpmA"
                     /locus_tag="ACF3UE_000205"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFD3633666.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(24470..25051)
                     /locus_tag="ACF3UE_000206"
     CDS             complement(24470..25051)
                     /locus_tag="ACF3UE_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3633667.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(25184..25867)
                     /gene="rpiA"
                     /locus_tag="ACF3UE_000207"
     CDS             complement(25184..25867)
                     /gene="rpiA"
                     /locus_tag="ACF3UE_000207"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFD3633668.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            26186..26599
                     /gene="rpsL"
                     /locus_tag="ACF3UE_000208"
     CDS             26186..26599
                     /gene="rpsL"
                     /locus_tag="ACF3UE_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFD3633669.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            26683..27153
                     /gene="rpsG"
                     /locus_tag="ACF3UE_000209"
     CDS             26683..27153
                     /gene="rpsG"
                     /locus_tag="ACF3UE_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFD3633670.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            27247..29334
                     /gene="fusA"
                     /locus_tag="ACF3UE_000210"
     CDS             27247..29334
                     /gene="fusA"
                     /locus_tag="ACF3UE_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFD3633671.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            29506..30693
                     /gene="tuf"
                     /locus_tag="ACF3UE_000211"
     CDS             29506..30693
                     /gene="tuf"
                     /locus_tag="ACF3UE_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFD3633672.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            31100..31408
                     /gene="rpsJ"
                     /locus_tag="ACF3UE_000212"
     CDS             31100..31408
                     /gene="rpsJ"
                     /locus_tag="ACF3UE_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFD3633673.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            31439..32068
                     /gene="rplC"
                     /locus_tag="ACF3UE_000213"
     CDS             31439..32068
                     /gene="rplC"
                     /locus_tag="ACF3UE_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFD3633674.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            32096..32719
                     /gene="rplD"
                     /locus_tag="ACF3UE_000214"
     CDS             32096..32719
                     /gene="rplD"
                     /locus_tag="ACF3UE_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFD3633675.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            32719..33009
                     /gene="rplW"
                     /locus_tag="ACF3UE_000215"
     CDS             32719..33009
                     /gene="rplW"
                     /locus_tag="ACF3UE_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFD3633676.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            33048..33881
                     /gene="rplB"
                     /locus_tag="ACF3UE_000216"
     CDS             33048..33881
                     /gene="rplB"
                     /locus_tag="ACF3UE_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFD3633677.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            33924..34202
                     /gene="rpsS"
                     /locus_tag="ACF3UE_000217"
     CDS             33924..34202
                     /gene="rpsS"
                     /locus_tag="ACF3UE_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFD3633678.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            34225..34572
                     /gene="rplV"
                     /locus_tag="ACF3UE_000218"
     CDS             34225..34572
                     /gene="rplV"
                     /locus_tag="ACF3UE_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFD3633679.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            34586..35242
                     /gene="rpsC"
                     /locus_tag="ACF3UE_000219"
     CDS             34586..35242
                     /gene="rpsC"
                     /locus_tag="ACF3UE_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFD3633680.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            35245..35679
                     /gene="rplP"
                     /locus_tag="ACF3UE_000220"
     CDS             35245..35679
                     /gene="rplP"
                     /locus_tag="ACF3UE_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFD3633681.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            35669..35857
                     /gene="rpmC"
                     /locus_tag="ACF3UE_000221"
     CDS             35669..35857
                     /gene="rpmC"
                     /locus_tag="ACF3UE_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFD3633682.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            35882..36148
                     /gene="rpsQ"
                     /locus_tag="ACF3UE_000222"
     CDS             35882..36148
                     /gene="rpsQ"
                     /locus_tag="ACF3UE_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFD3633683.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            36206..36574
                     /gene="rplN"
                     /locus_tag="ACF3UE_000223"
     CDS             36206..36574
                     /gene="rplN"
                     /locus_tag="ACF3UE_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFD3633684.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            36611..36919
                     /gene="rplX"
                     /locus_tag="ACF3UE_000224"
     CDS             36611..36919
                     /gene="rplX"
                     /locus_tag="ACF3UE_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFD3633685.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            36947..37486
                     /gene="rplE"
                     /locus_tag="ACF3UE_000225"
     CDS             36947..37486
                     /gene="rplE"
                     /locus_tag="ACF3UE_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFD3633686.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            37505..37690
                     /locus_tag="ACF3UE_000226"
     CDS             37505..37690
                     /locus_tag="ACF3UE_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFD3633687.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            37726..38124
                     /gene="rpsH"
                     /locus_tag="ACF3UE_000227"
     CDS             37726..38124
                     /gene="rpsH"
                     /locus_tag="ACF3UE_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFD3633688.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            38156..38692
                     /gene="rplF"
                     /locus_tag="ACF3UE_000228"
     CDS             38156..38692
                     /gene="rplF"
                     /locus_tag="ACF3UE_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFD3633689.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            38853..39209
                     /gene="rplR"
                     /locus_tag="ACF3UE_000229"
     CDS             38853..39209
                     /gene="rplR"
                     /locus_tag="ACF3UE_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFD3633690.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            39230..39730
                     /gene="rpsE"
                     /locus_tag="ACF3UE_000230"
     CDS             39230..39730
                     /gene="rpsE"
                     /locus_tag="ACF3UE_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFD3633691.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            39745..39924
                     /gene="rpmD"
                     /locus_tag="ACF3UE_000231"
     CDS             39745..39924
                     /gene="rpmD"
                     /locus_tag="ACF3UE_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFD3633692.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            39968..40408
                     /gene="rplO"
                     /locus_tag="ACF3UE_000232"
     CDS             39968..40408
                     /gene="rplO"
                     /locus_tag="ACF3UE_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFD3633693.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            40408..41703
                     /gene="secY"
                     /locus_tag="ACF3UE_000233"
     CDS             40408..41703
                     /gene="secY"
                     /locus_tag="ACF3UE_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFD3633694.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            41765..42412
                     /locus_tag="ACF3UE_000234"
     CDS             41765..42412
                     /locus_tag="ACF3UE_000234"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFD3633695.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            42603..42821
                     /gene="infA"
                     /locus_tag="ACF3UE_000235"
     CDS             42603..42821
                     /gene="infA"
                     /locus_tag="ACF3UE_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFD3633696.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            42854..42970
                     /gene="rpmJ"
                     /locus_tag="ACF3UE_000236"
     CDS             42854..42970
                     /gene="rpmJ"
                     /locus_tag="ACF3UE_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFD3633697.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            42988..43353
                     /gene="rpsM"
                     /locus_tag="ACF3UE_000237"
     CDS             42988..43353
                     /gene="rpsM"
                     /locus_tag="ACF3UE_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFD3633698.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            43381..43770
                     /gene="rpsK"
                     /locus_tag="ACF3UE_000238"
     CDS             43381..43770
                     /gene="rpsK"
                     /locus_tag="ACF3UE_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFD3633699.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            43850..44788
                     /locus_tag="ACF3UE_000239"
     CDS             43850..44788
                     /locus_tag="ACF3UE_000239"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFD3633700.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            44816..45196
                     /gene="rplQ"
                     /locus_tag="ACF3UE_000240"
     CDS             44816..45196
                     /gene="rplQ"
                     /locus_tag="ACF3UE_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFD3633701.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            45468..46307
                     /locus_tag="ACF3UE_000241"
     CDS             45468..46307
                     /locus_tag="ACF3UE_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD3633702.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            46283..47152
                     /locus_tag="ACF3UE_000242"
     CDS             46283..47152
                     /locus_tag="ACF3UE_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD3633703.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            47142..47939
                     /locus_tag="ACF3UE_000243"
     CDS             47142..47939
                     /locus_tag="ACF3UE_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFD3633704.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            48142..48888
                     /gene="truA"
                     /locus_tag="ACF3UE_000244"
     CDS             48142..48888
                     /gene="truA"
                     /locus_tag="ACF3UE_000244"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFD3633705.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(49343..52012)
                     /locus_tag="ACF3UE_000245"
     CDS             complement(49343..52012)
                     /locus_tag="ACF3UE_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFD3633706.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFFYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(52250..52438)
                     /gene="rpmB"
                     /locus_tag="ACF3UE_000246"
     CDS             complement(52250..52438)
                     /gene="rpmB"
                     /locus_tag="ACF3UE_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFD3633707.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            52708..53070
                     /locus_tag="ACF3UE_000247"
     CDS             52708..53070
                     /locus_tag="ACF3UE_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3633708.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            53122..54804
                     /locus_tag="ACF3UE_000248"
     CDS             53122..54804
                     /locus_tag="ACF3UE_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFD3633709.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            54921..56957
                     /gene="recG"
                     /locus_tag="ACF3UE_000249"
     CDS             54921..56957
                     /gene="recG"
                     /locus_tag="ACF3UE_000249"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFD3633710.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            57006..58007
                     /gene="plsX"
                     /locus_tag="ACF3UE_000250"
     CDS             57006..58007
                     /gene="plsX"
                     /locus_tag="ACF3UE_000250"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFD3633711.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            58129..58371
                     /gene="acpP"
                     /locus_tag="ACF3UE_000251"
     CDS             58129..58371
                     /gene="acpP"
                     /locus_tag="ACF3UE_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFD3633712.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            58639..59643
                     /locus_tag="ACF3UE_000252"
     CDS             58639..59643
                     /locus_tag="ACF3UE_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3633713.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            59644..60588
                     /locus_tag="ACF3UE_000253"
     CDS             59644..60588
                     /locus_tag="ACF3UE_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3633714.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            60588..61550
                     /gene="opp4B"
                     /locus_tag="ACF3UE_000254"
     CDS             60588..61550
                     /gene="opp4B"
                     /locus_tag="ACF3UE_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFD3633715.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            61577..62491
                     /locus_tag="ACF3UE_000255"
     CDS             61577..62491
                     /locus_tag="ACF3UE_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3633716.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            62517..64298
                     /locus_tag="ACF3UE_000256"
     CDS             62517..64298
                     /locus_tag="ACF3UE_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3633717.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            64646..65332
                     /gene="rnc"
                     /locus_tag="ACF3UE_000257"
     CDS             64646..65332
                     /gene="rnc"
                     /locus_tag="ACF3UE_000257"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFD3633718.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            65352..68933
                     /gene="smc"
                     /locus_tag="ACF3UE_000258"
     CDS             65352..68933
                     /gene="smc"
                     /locus_tag="ACF3UE_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFD3633719.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            68942..69751
                     /locus_tag="ACF3UE_000259"
     CDS             68942..69751
                     /locus_tag="ACF3UE_000259"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3633720.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            69762..70760
                     /gene="ftsY"
                     /locus_tag="ACF3UE_000260"
     CDS             69762..70760
                     /gene="ftsY"
                     /locus_tag="ACF3UE_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFD3633721.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            70947..73214
                     /gene="gshAB"
                     /locus_tag="ACF3UE_000261"
     CDS             70947..73214
                     /gene="gshAB"
                     /locus_tag="ACF3UE_000261"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFD3633722.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(73303..73755)
                     /locus_tag="ACF3UE_000262"
     CDS             complement(73303..73755)
                     /locus_tag="ACF3UE_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFD3633723.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            73905..74855
                     /locus_tag="ACF3UE_000263"
     CDS             73905..74855
                     /locus_tag="ACF3UE_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFD3633724.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            74848..75807
                     /locus_tag="ACF3UE_000264"
     CDS             74848..75807
                     /locus_tag="ACF3UE_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFD3633725.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            75804..76559
                     /locus_tag="ACF3UE_000265"
     CDS             75804..76559
                     /locus_tag="ACF3UE_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3633726.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            76582..77535
                     /locus_tag="ACF3UE_000266"
     CDS             76582..77535
                     /locus_tag="ACF3UE_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3633727.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(78179..78475)
                     /locus_tag="ACF3UE_000267"
     CDS             complement(78179..78475)
                     /locus_tag="ACF3UE_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFD3633728.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
BASE COUNT        25260 a        14199 c        17053 g        21968 t
ORIGIN      
        1 tataaagagt atccagagta ttttatttta acttttgtat atttagtaag tagctacaca
       61 cttctatata aattcagaag ttcttctaga gtttctaaag tttgtttctt aattagctta
      121 ttgattctat aatatttttg atttatatag gaaattaaaa atattataga atcaacactc
      181 agagaacggg ttggttttta atagatttaa taagtactga taatgaaatt tctcctggtt
      241 gggaaaacga agttggttac cctgtagaag aattttttca agattacttt gcggagtatg
      301 ccgataggat aatgagagat tacgtaacag ataaaactca agaagtcatc aatcaatccc
      361 agtcattaaa tgaattatct gataaggcga aagaagaagc agttgccatt atttcttcag
      421 ggattagtga ctatattgat atgagtggtg aaatcaatta tggcgataaa gacaaaattg
      481 tacgcatgat aaaagctttt atcaaaactt ttgatgtgaa ggcagatctt aagtttaatg
      541 atacttacct agtaggaaaa ttaattaata tccttgggac agagaaagat acggaaacgt
      601 ttatttcctc tttgtctatg ttgtttacag ataagcattt ttcaactcag cttggtggag
      661 aggaactagt ggaaatcttt taaccattac gcccagcatt aataaaagta tatcaaaaaa
      721 gtactcctga tgatttttaa gattggtttg agaaataatg tgaaaacact atttttaatg
      781 ttaattatag atagagatga acgcgtcata tggttaaaag aatgaaaaag tcaaagatac
      841 actgctatat ttcactaagg atatagcagt gtatctttca tgtcgtttca ctggcagttt
      901 tttataaaag gaggtgtgca tttcagttgc ttttctttgg tagttagttg aatcgtttaa
      961 gaattaacgg atgtggcaga caggtgctct gtccaaaaac cagtaaaatc tttgatggtt
     1021 ccatctttat ttagctgtgc ctgttcaaat actgttttgt ttttaccgaa tggatcaatt
     1081 gcaataattg ttccgatccc cgcacgtttg gcagcaagta atcctgagta agcatcttcg
     1141 ataacaagac aatcagccgg agctaagctc agtttgtctg ccgctttaag aaaaatatcc
     1201 ggttgcggtt tcccagggaa agagccgtcg tcatagacaa tcttgtccca gtcaaaccag
     1261 cgggctaaat cgaaaatatc aaaataaaaa gcaacattct ctttgacagt agccgtggca
     1321 atcgttaatg gaatctgttg gtcagtcagc tggtcaagag tcgcttcaag cccttttgtc
     1381 aactgaagct cgttttcatt ttgcaagcaa agcatacgat aatagctttc tttttcttct
     1441 gacaatacgg cgatctcaga ggcggtcaaa tgctctgaaa tgaaatgttt caaaatctcc
     1501 gtattcgtcc gaccatgaat attttttaaa atatcctcgt ctgataaacc atcttttgta
     1561 tgatcatgta tcatatgcag ccaagcagct tcatgcagat gagagtccaa aaacattgtt
     1621 ccgttgaaat caaatataat ccctttcata gttacgctcc tatagtggta ttttcggttg
     1681 aatcagcaat ttgcagatcg acatattgtg catagtgctc ttgaacctcc cgcgagatct
     1741 ggcgatccgt aatgagcaga tcgaaatcat gcaaattata aaacacataa aaatcatctc
     1801 gattgaattt tttattatca acgagtagat atttcttacg ggaattattt agagcgatct
     1861 gctgtgcttc tccttcttcg gtactgtaag tagagatcgc ttcgttgtga acgccatttg
     1921 aactgataaa tgcttttgta aactttagtc ttcttaaatt gtcgttggtg atcggtccga
     1981 caaatgcgcc ggtatttttc cggaaatcac cgccaatcag tagaatttct ggtccatctg
     2041 cttgagcaag aatatcaaaa actggataat tatttgtaat gatccgaatt ttcttgttca
     2101 gtaaatgcgt cgccaatagt tcgattgttg tacctggtcc taagaaaatc gtttctccct
     2161 cgtgaatcaa ggaggctgct gtggcagcaa tttctttttt ttcttgaatc tgcagagtgg
     2221 ctttttcagt gtgagaaagt tcttgatcta aagtgtagga aagactttga gcccctccat
     2281 ggacacgcag cagcttgccc gatttttcta attcatctaa atctctgcga acggtcatat
     2341 cagaaacatc taattgattg atgatttcat taacggtaag gattcctttt ttattgacca
     2401 tttctacgat agtaagcaat ctttcttttt tcaacattgt cttcacctct aatttaagga
     2461 taatctatca tataaacgga caacagtcaa tctaattcga acaaaagtaa acatttaggg
     2521 tggtttttat gtttgttaca atagatttta ttgctgtttt ctggttttta tgattatttg
     2581 tgtttgtttt tgttgacaaa tgttttggat gcgtttacaa tgcaatcagt tagaaagagc
     2641 gaaaactgat tatagatttg aggagagatg tacatgctta aattaccaga agattttatt
     2701 tttggcggag ccacagcagc ctatcaggtt gaaggagcca ctaaggaagg tggcaaaggc
     2761 gctgttgctt gggatgactt tttagaggaa caagggcgat tcagtcccga tccggcaagt
     2821 gatttttatc atcaatatgc aaaggacatt gaattgtgtg aacgttttgg tgtaaatggt
     2881 ctaagattat ccattgcttg gagccgcatt tttcctgatg gagctgggaa accaaatcca
     2941 gaaggaatcg ctttttatca tcgtgtgttc gaagaatgta agaaaagaaa cgtaacgccg
     3001 tttgtgacgt tgcatcattt tgatacccct aaacgtttgt ttgaccatgg agattttttg
     3061 aatcgagaaa caatagaagc atttgtttcc tatgccattt tttgttttca tgaattcaaa
     3121 gaagtcaagg tgtggagtac ctttaatgaa atctatccag ttgcaaccaa tcaatatttg
     3181 ttaggtgttt tcccaccagg aatcaaatat gattttacaa agatcgtcgc ctgtcttcat
     3241 aatatgatgg ttgctcatgc ccgtgtagtg aactatttca aagaaaacga acttccgggt
     3301 gaaattggtg tagttcactc attagagacg aaatatgcgg caacagacgc gccggaagat
     3361 aagcatgctg cctttttaga cgatgcattg tcgatccgtt tcttattaga tgctacctat
     3421 ttaggctatt attcaactga aaccttgact gctcttgatg agatatgtga agcaaatcag
     3481 gccagctatc attttcctga agaagatttc gttgaattga aaaaagcatc cacgcgtaat
     3541 gactacttag ggatcaatca ctaccaatgc cattttgtca aagcttacga tggagaaaat
     3601 gcaatccatc ataacggtac gggtgaaaaa gggacctctg tttataaagt gaagggaatc
     3661 ggagaacgta tttataaaga aggaattcct cgaactgatt gggactggct gatttatcca
     3721 gaaggtctat atgacttgtt gctgcgaatt aaaagcgatt acccacatta caacaaaatc
     3781 tatatcactg agaacgggat ggggtataaa gatcagtttg aagatggcat tattatggat
     3841 cagccgagaa tcgactattt gagagtctat ttggaatcct taagcaaggc gataacagcc
     3901 ggggtaaatg tgaaggggta ttttttgtgg tcgcttatgg atcttttctc atggacaaat
     3961 gggtataaca aaaggtatgg cttgttttat gttgattttg aaacccagaa gcgttaccca
     4021 aaagaatcag cttactggta caagttggtc agtgaaacca aaacgattat ttaataagtg
     4081 ataatggagg aagaaaagat gaataaagag gaattacaaa tgcttggttt tgagatcgtt
     4141 gcatattcag gcgacgctcg cagtacatta ttgaaattat tgaaagaagt aagacaagga
     4201 aactttgaac atgttgattc ggcgttgaaa gaagccgacg aaaatttaac ccttgcacat
     4261 aattcgcaaa caaaaatttt agcggaagaa gcatctggga aagagatgga gatgggattc
     4321 atttttatcc atgggcagga tcatttaatg accactttat tgctgagaga tctgattcaa
     4381 gactttattg tactgtacag acagaatcaa ggataggaga agaacgctat ggatggaatc
     4441 attaaacaaa tcgaaaaagg gaaagcattt tttgaaaaaa tctcacgtaa tagttattta
     4501 ggagccgttc gtgacggatt tttaacagcg atgccagcta ttttattttc aagcattttc
     4561 attttgattg ctgcggttcc tgagattttt ggttaccaat ggcctgaatc tgtctccaca
     4621 tggctatgga aagtctataa ttattcgatg ggtgttgtag ggttactcgt ttcagcaacc
     4681 actgctcgct gcttggctga ttcgatgaat cgtcgcttac cgaaaaacaa agtaatcaac
     4741 accacctctg tgatgctggc ctctgtggta agtttcctgt tgttaagcgt ctctccgatt
     4801 gaaggtggat tttcaacgga atatatgggg acaaagggac tactggcttc ctttgtcgct
     4861 gcatttttaa cagttaattt atataagttt tgtgtgctga aagatattac cattaaaatg
     4921 cctaaagaag ttcctggaac gatttcgcaa accttccgag atatttttcc tttctctttt
     4981 tcagtatttg cggccgtttt aattgattta ggcattcgac aaatcttcca aatctcattt
     5041 gcagaagcaa tcattacggt gctgcagccg ctatttacag cagctgacgg gtacttagga
     5101 atcgctatta tctggggagc gatggcgctg ttttggtttg tcggtgttca tggaccgtcg
     5161 atcgtggagc cggcaattgc ggcaattatc tatgccaatg tggaaaccaa tctgcaattg
     5221 ttcaattccg gtgaacaagc ttctaaagta ctgacggtgg gtttagggaa ttttgtagga
     5281 actatgggag gaactggggc aacattggtt gttcctttta tcttcctact ctttgctaag
     5341 tctaagcagt tgaaggcagt tgggaaagct tcctttattc cagtaagttt cgctgtcaac
     5401 gaaccattgc tatttgcggc acccatgatt ttgaaccctt atttttttat tccatttttg
     5461 ttaacacctg ttgtaaacgt ttgcctgttc aagttttttg tcgatgtatt gggcatgaac
     5521 agctttatgt acgttttgcc ttgggcaact ccagcaccga tcggtttggt tctaggaacg
     5581 ggcatgggta tcttagcttt tgttctagca gcggttctaa tcgtcgttga cttcctgatc
     5641 tatctaccat tttgcaaagc atacgatgct gtcttagtag agaaagaagc acaaaaagca
     5701 gaggtgatcg caaccgagga aggtgcttct gccgatgtac gtgaggaagt acctgtggca
     5761 gcgagtcaag ttatcagcga tgcaaataaa gaaatcaatg tgttggtact ttgtgctggc
     5821 gcagggacaa gtgcgatgtt agctaatgct ttaaaaaaag gtgcatctga atcgaaagca
     5881 ccgatcagtg caatggcggg tgcttatggt tctcattacg aaatgctgca ggattttgat
     5941 atggtggtct tagcaccgca agtcaattct tactatgatg atatcaaaga agacaccgat
     6001 cgcttaggaa tcaagctggt tgcgacaaaa ggagcagaat atatcggatt aacgagagat
     6061 cctgaaaaag ctgttcagtt tattctgaac caatttcaat aaaggaggag ccataatgaa
     6121 aatgggaatt tggttgcgta aagctgtttt atttgcagct gtgttagggg ctttgggggc
     6181 tgtttcaaaa actgttgaag catctgccag cgaatttatt cgcggagcag atatttcgat
     6241 cctgtcagat atggaaaaat ctggtgcaaa atattatgaa gacgatattt caaaagatgc
     6301 cttagagatt ttaaaaaata atggtgtcaa ctatgttcga ctgcgtttgt ggcaggatcc
     6361 ttataatagt aatggagaaa gttatggagc agggacaaat gatctggaaa cgacgattga
     6421 ccttgcaaaa cgagcaaaaa atctgggact taaggtgctg ctggattttc actacagtga
     6481 tttttgggtt gatcctggga aacagaatct tcctaaagca tggcaaggtc tgacctttga
     6541 agaaatgaat acggcattgt acgactatac aaagaacgtt ctgtcggaaa tgaagcagct
     6601 ggacgtttat cctgatatgg ttcagatcgg caatgaactg aatagcggaa tgctctggcc
     6661 ttatggcaag tcttggggag aaggcggggg agaatttgat cgattggctg cttttttgaa
     6721 gtctggtatc caagctgttc gagacactca acctaaaaca actccagtaa tgctccactt
     6781 agctgatggt ggcgatacag gagcatttac ttggtggttt gatgaaatca cgagtcgagg
     6841 tgtgtcattt gatttaattg gagtgtcgta ttatccgtat tggcacggtt caatgaatga
     6901 acttcaaacc aatatgaatg cgatcagcca acggtatggt aaagaagtga tcgtagttga
     6961 aacagcttat gggcatacaa cagcgaatgc cgatactatg ccaaatgctt ttggtgaagc
     7021 cgaagcagct gcggggggat atgaaccaac accgacagga caagcagagt atttgctgga
     7081 tcttgccgat cggattcagg cagtaccgaa taatcgcggg gcgggcttct tctattggga
     7141 acctctttgg tacaacggaa atgtgagttg ggcaacacaa gcaggtatga attatctcag
     7201 tgttcaatcc actatgggaa acgaatggga caaccaagcg atgtttgatt ttgctggaaa
     7261 cgccttgcca agcttgcgtg cgtttaaaca agcaggggcg caaataaatc tagttaaaaa
     7321 tgcaagtttc gaaagcgatg gaccaacgac cagtccttcc aattggcaaa cctggtttca
     7381 acaaggaacc gctaagggta cgatcaaaac ggaagcgggc actttttttg gggactacaa
     7441 actaactttt tggcaggatc aagcatacga ggcatcagct tatcaaaatg ttagtggcat
     7501 aagcaaagga acttacacat tgagtgccta tgtaatgtct gggggagagt ttgatactaa
     7561 tcagttatat atcaaaaatt atggtggagc ggaactaaat actgcggttg ttaaaacaag
     7621 tgaatggaca aaaattacaa tcaaagacat tccaattaca acaggtgttt gtgaaattgg
     7681 ggtttatagc aaggcttcag gaaatgcttg gacgaacgtt gattttgttt cattggtgaa
     7741 acaatagact gcggatcgtt tcgattcaag atcggaggtt cccttcagcc acatcgttag
     7801 cgtagaaggc aggaatcgaa cctgcacctc gcctttgcca aaaataacca gaaacgattt
     7861 ccagtcattt ttaccaaaac gagtaaagca ccagacttca tctacacttt gtattatgct
     7921 aaagagagtt caacgatttc gtaagaagca atgaaaaaat tgcaaaaagt tgtgcagata
     7981 acataaagtt tgtttaagaa agggtaacct tagaattccg tcgtgaatat gatttgagca
     8041 cttagatgga tagaaaaaag ttctcggaaa acagttcgtt tttcgagaac ttctttttat
     8101 gataagaatg aaacaaatta acttatatta tagtctcttt tggtagggaa ccatcttatt
     8161 tttaatgaaa atcaagcatt ttagctattg aagaatgttg atttataggg attccccctc
     8221 catattatgt tggctcttta ttcccactcc actgttgctg gtggtttaga agtgatgtca
     8281 tacacgatac ggttgacgtg ggctacttcg tttacgatac gtacagagat tttttgcaag
     8341 acttcccatg ggatacgggc aaagtcagcg gtcattccgt cgattgaagt tacagcacgg
     8401 ataccgactg tgtagtcgta agtacgtccg tcacccataa caccgacaga gcggatccct
     8461 ggaagaacag tgaaatattg ccagatatca cggtcaagtc cagcagctgc gatttcttca
     8521 cgcaagatag catcagattc gcgtacgatt tctagcttgt cttcagtgat ttcgccaaga
     8581 acacgaatac caagaccagg accagggaat ggctgacgcc aaacgattga atcaggcatg
     8641 cctaactgag tccctaattc acggacttcg tctttgaata atgtgtttaa tggttcgatc
     8701 aattcaaatt gcatatcttc tggcagtcca cctacattat ggtgagattt gatcgtctgt
     8761 gctgtttctg taccagattc gataacgtca gtatacaacg ttccttgtgc taggaaagag
     8821 acgccttctt caccagcaag ttttgttgct tcgtcatcaa aaacatatac gaattcattc
     8881 ccaatgattt tacgtttttg ttctgggtca gatacacctt tcaacttgtc taagaagcga
     8941 tctcttgcat tgactttgat gatgttcaag ccgaattttc cgcctagact ttccattact
     9001 tgttccgctt cgcctttgcg tagcagaccg tggtcaacaa agatagatgt caattggtca
     9061 ccgatcgctt tttgtaaaag aaccccaacg acactagaat caacgccacc tgaaagacca
     9121 agcaagactt ttttgtcacc aacttgttca cggatttttt ctacttgcat atcgataaag
     9181 ttatccattg tccagttacc ttcacagtga caaacatcaa aggcaaagtg gcgcagcaat
     9241 tcgattccgt attcggaatg acgtacttct gcatggaatt ggataccata aaaattacgt
     9301 gttgtgtctt ggatagaagc aatcggacaa tctttgcttg ttccgactgt ttcaaagcct
     9361 tcaggaactt tagttaccaa gtcaccatgg ctcatccata ctgtttgttg ttttggtgtt
     9421 tctttaaaca agacagcttg atcgcttgtt acttctaaca aggctttccc atattcgcgg
     9481 tttttagcag gctctacgga accgccaagt ttgtacgtga tcaattgcat accatagcaa
     9541 atccctaata caggaatacc taaattgaag atctcaggat cgatcccaaa tgcattctca
     9601 tcatatacac tgtttggtcc gccagaaaga atgattccct ttggattcat cgcttttact
     9661 tcttctgcag taatgcggtg gctcaataat tcggaaaaga ctccaagatc acgaatacgt
     9721 cttgtgatca attggttata ctgactaccg tagtctaata cgataatctt ttcaacgttc
     9781 gtcatatcgg caacgtttgt caaatttatt acccctatcc ctttaaattt tatctcaaaa
     9841 tagtcaaact attttaaaat gctaatattt tcgcatgaaa atcgaatcga tgatatgatt
     9901 ttcagtttta tggagaatta tatcggctct tcctcgtgta ggcaagatat attcctgtaa
     9961 atttttcaaa ttcacatttt tccatacatc ttttgccatt ttaaaggctt cttcacgatc
    10021 tccgatagca aaacgataat aataattctc tggattttgg aaagccgtat ccagtaacgc
    10081 accaaaacga tccaaatacc atttttcgat cagcacggga tcggcatcga catagacaga
    10141 aaaatcaaaa aagtcgctga cgtagatttg ctgattcgca ggtaattgaa gcgtattgat
    10201 cccctcaacg atcaagatat caggctgctg gatcaattcg tacttgtctg gaatgatatc
    10261 atacacatca tgtgagtaaa caggtacttt tatctcttcc tgaccagatt ttacacggtt
    10321 caagaaatcg atcagcatct ccatatcata actttcagga aatcctttac ggtccatgat
    10381 tccacgctct tttaatatac gatttggata aagaaatccg tcagtcgtga tcagctgaac
    10441 gtttcttcgt ttgaaggtac gagacaaaat cgtctgcagc agtctggctg ttgtactttt
    10501 tccaacggct acacttccgg cgatcccgat aataaaaggc ggtacttcta cgtatttatg
    10561 aagaaataaa cctttactca agaacaaaga ttcaaattct ttcatataaa gataaatcag
    10621 atgagcaaga ggtacataga tatctcgaac atcctgcatg gaaatgcggt cattcaaact
    10681 tttgatatta tctagttcat cttgtgtcaa aggtgcttgc ccattacgat aaaattctcg
    10741 ccattcttct cttgccacac ggtagtagtt cattggatca ttcatattag cctcctgcgt
    10801 tctcccatca atggaactat tttaacacaa aataaacgca aaccccacca cttaagagag
    10861 attgccgatc tttttgtata atctttataa tagaaagaaa cggagtctta ttcttgactt
    10921 gcgcacggat acataaaagg atagactgtt gtcatgaaag aaatgagaag gatggaagac
    10981 atgacaaatc attactattc tgaacgccca gatacggcgc acgattttga acaatgggct
    11041 tttgagttaa aaggcagaac ctttcaattt gtaacagatt ctggtgtatt ttcacgtgaa
    11101 acagtggatt atggttcacg tgtcctgatt gatgctttcg attgggaaga gttacctgat
    11161 gaaggaaaga tcttagatgt gggatgcggg tatggaccga ttgggttagc tttggcattt
    11221 gcgacacagc ggtttgttga aatggtcgac attaatgaac gagcggtaag tctagcgcaa
    11281 ggaaacgcaa agcgtaacca aatcgaacat gttgatatcc atcaatcgaa tatctatgaa
    11341 gcagttcatg aagaaaccta tgcagctatc gtaagcaatc cgccgatccg tgctggaaaa
    11401 aaagttgtac atgaaatttt gacaggcgca tatcctcggt tgaagaaggg cggtacactg
    11461 acaattgtga tccagaagaa acaaggagcg ccgagtgcgc aaaagaaaat ggaagaaaca
    11521 tttggtaatg cagaaatcgt cacaaaagat aaaggatatt atatcatcaa aagtgtgaaa
    11581 gaataactag ctgaaaaata gtggagcgac gaaagagtgg aactgggcgt gcatgtacgg
    11641 gtacgtatca gttctttttt tgttgagaag tttttaaaaa caaagaacta ttttttcttc
    11701 aaaaagaaat agtaggaaca gagtcgttgt tttttacgat aaaataaata agatacagaa
    11761 cttgtataga aggctgccaa gtcggtagat aaaggaggtt tttatcaaaa aacatacttt
    11821 ccttttttct ctattctttt cttgggggtt ttggtacact gatagggaat ttagatagaa
    11881 gggagccaat aggatgaagc tgaccatcag agatatcgca gaaatggcag gcgtatcagt
    11941 aacaactgtc tcacagattt tgaataacaa aggaagcaga tttagtgata agacaagaaa
    12001 aaaagtgttg tcgatcgtga atgaacatca ttataagccc gattatttcg cttcaaatgt
    12061 gatcaatcga cattcaaaga ccatcggaat gatcgtccct gatgtcactg atttcttctt
    12121 ctccaaactg atcgaaggtg tagagagcta tttgaatcct ttgggctatg tgatcatgtt
    12181 atgcaattct cgtcatagcc aagaaaatga gatcaagtat ttacaagagc tttcccaccg
    12241 ctcagtggac ggaatcttgc tggccacacc aaatatttta cctgagaaat atgcattaga
    12301 cagcggtttt tatcaaaaaa tgccaatcat tttaatcgat cgcggattga atcgtcggga
    12361 taacggacgg cttatcgtaa aggaatatga gggcgcctat caagctgttt cgctgtttat
    12421 tgaaaatggc catacgaaga tcggcatgct gaaggaaacc actggatact atcaattaga
    12481 agaacgtttc aacggatatc gtcatgcgct gaaagatcat ggcctgcctt ttaatgggaa
    12541 atttgttgaa catggagagt tgactgtcca aggtggatat actgcatcaa aaaaattact
    12601 caaacataaa gatatcacgg ctattttttg cgggaatgat gccatggcga tcggatgcta
    12661 tcaggcgatc gatgaattgg gcaaaaaaat cccagaagat atctcagtca taggattcga
    12721 tggattaaag ctgtcagaat acatgattcc gcaattgacg acagtgcagc agccaagttt
    12781 tgatattgga ttttatgctg cacgtttcct gatcgatacg atcgaatttc ctcaaagaaa
    12841 agttccgaac aaagtgttcg aaacaaaatt aattattcgt gagagcgtaa aagtattgac
    12901 aaagggctaa ctcggcggta tattgcttat gtaagcattt acaaaggcta gttagtgctt
    12961 tttttatttt tagtaaacca gtttactaaa gtggtttacc tttcctaaaa ataatgtata
    13021 ataccgaatg aagacaagga ggatcaggca atgcgaatgg tggatctgat tgaaaaaaag
    13081 agggatggaa acgagctgtc gaaagaggaa atcgagtaca tcgtcacgaa ctatacgaat
    13141 ggaaagattc cagattatca agtcagtgca ttattgatgg caatttttta tcaagacatg
    13201 acaaatgaag aaatcacgaa cttaacattg gcgattgcta attctggtga tgtcatcgat
    13261 ttgagttctc ttgaaggaat aaaggtagat aagcattcga caggtggcgt tggtgacacg
    13321 accacattga ttttagcccc cctagtagct agtgtcggag tgacagtggc taaaatgtct
    13381 ggacgcggtc taggttacac aggtggtaca ctagacaagc tagaagcaat tcccggattt
    13441 cagatcgagc tttcggatga agaatttgta cgcattgtta atgaaagtaa agtagcggta
    13501 attggtcaat caggaaactt ggcaccggcg gacaaaaaat tgtatgcctt gcgtgacgtc
    13561 acagcgaccg ttgattctct tccgctgatt gccagttcga ttatgagtaa aaaaatcgcg
    13621 gcaggagcag atgcaatcgt tttggatgtg accactggag acggtgcttt catgaagaac
    13681 atcgaagatg caagacgtct ggcaaagacc atgacgagca ttgggaaact ggctaaccga
    13741 gaaacagtgg cggttatctc agatatgtca gaacctcttg gcgaagctat cggaaatagt
    13801 ctagaagttg tcgaggcaat cgaaacatta caaggaaatg gtccagaaga tctagtagaa
    13861 atgtgctacg ccttaggaag ccaaatggtt gttcttgctg gcaaagctaa gacaaccgat
    13921 gaagcaagaa cgttgcttca agaagctctg gaatcaggta aagcgttagc aaaattcaaa
    13981 gaaatgatcc aaaatcaagg gggagaccca gcgatcgtgg aacatccaga acgaattttg
    14041 actgcacgct acacaatgga gcttcctgct aaacaaagcg gagttgtgtc aaaaatcgtg
    14101 gcaaatgaat taggaattgc tgcaatgatg ctaggtgctg ggcgtaaaac caaagaagaa
    14161 gatattgatc acgctgttgg attgaaactg cataaaaaaa ttggtgacac tgtgacaaaa
    14221 ggtgagtcac tattgacgat ctatagtaac gacgaagaaa tcacttctgt cattgaatta
    14281 ttatataaaa atattgaaat tggtgaatcg gcaatgaagc caacgttgat tcatgacatc
    14341 atcacagaat aaaggaaaaa agcggacttt accgttttaa agaaaagggg aaaagaaatg
    14401 gaactaaacc gaatgatcga ccatactatt ttgaaagcag acgcatctaa agaagctgtg
    14461 atgcaaatta tcgaagaagc aaaaaaatac catttttatt ctgtctgcat caatccagca
    14521 tgggttgcgc tagcgaaaga acaattacaa ggtgagccag tagccgtatg tacagtaatc
    14581 gggtttcctc taggagcaaa cacacccgag acaaaagcat ttgaaacaac agatgccatc
    14641 aataacggtg cagatgaagt cgatatggtc atcaatatcg gtgctttgaa atcaaaggat
    14701 gatcaacaag tccaaaaaga tatcgaagca gttgttgaag cagcaaaaga tcgtgcgctt
    14761 gtcaaagtta ttattgaaac atcgttatta gatagagaag aaatcatccg agcttgcgaa
    14821 atagcaaaag ctgcaggcgc tgattttgtc aaaacatcaa ctggtttctc aacaggcgga
    14881 gcaaaggtag aggatgtccg tttgatgcgt gaaactgtag gaccagaaat gggtgtcaaa
    14941 gcttccggcg gtatccataa cgaagaagaa gcaatggcaa tgatcgaagc tggtgctaca
    15001 agaatcggaa caagcgcagg agtagcaatc gtatctggtt caactggtga aggctattaa
    15061 ttttttcaaa ggagaagctc atggcagaac tcaaacaaga atggatcaac acagctattg
    15121 aagcgttaga taaagcctat gttccttatt cccattttcc ggtaggcgct tgtctcgtaa
    15181 cggaatcagg caagatttat caaggcatca acattgagaa tgcatcattt ggattaacga
    15241 attgtgccga gcgcacagct tttttcaaag cagtatctga aggagaaaaa acatttacgc
    15301 atctagtcgt agcggggcac acccccgatc ctatctctcc ttgtggtgca tgtcgacaag
    15361 taatggcaga attctgttcc cctgatatgc cggttacgct agtaggagac aatggtgtga
    15421 cgaaggcaac gaccgttcgt gcactgctgc cttatgcatt tactgaaaaa gatctataac
    15481 tcatgttcat tcagtcagct gactgttgaa aaataaaaca attattttag gaggctttac
    15541 agaaatgaaa aaagcaaaat tatttggttt aggtgctgtc gcactagcag cagggttatt
    15601 tttaggtgca tgcggcaaca acggctctac tgattcatcc ggtggcaaaa gctcatcaga
    15661 cacaacaact gcagcattga tcacagacac aggtggtgta gacgaccgtt cattcaacca
    15721 gtcagcttgg gaaggactag aaaaatgggg gaaagatcaa ggactttcac gaggaaatga
    15781 tggcttccaa tatttccaat cttcaaatga atcagattac atcccaaata ttgaccaagc
    15841 attgaatgct ggattcaaaa cgatttttgg tattggttat aaactaaaac cagcgatcca
    15901 agaacaagca acaaacaata caggtacgaa ctttgttatt atcgatgatg tcatcgatgg
    15961 attagataac gttgtatctg caactttcaa agacaacgaa gcttcttatc ttgcaggtgt
    16021 tgcagcagct tatacgactg aaacaaacgt agtcggcttt atcggcggtg taaaaggtga
    16081 agtaatcgat cgttttgatg ctggattcaa agccggtgtt gatgcaggtg cgaaagaatt
    16141 aggaaaagaa atcaaagtat tgaatcaata tgctggtgac ttctctgctc cagataaagg
    16201 acgttcaatt gctcaaggta tgtatgcaca aaacgcagat atcatcttcc atgcttcagg
    16261 cggtacaggt aacggtgtat tccaagaagc aaaatcattg aacgaatcag gcgacaaaaa
    16321 agtttgggtt atcggtgttg accgcgacca atcagacgaa ggcgaataca cattaaacgg
    16381 cgaaaagaaa aacttcacat tgacatctac actgaaagca gttggaacag tagtagaaga
    16441 tttggcacaa aaatcagcgg acggtaaatt ccctggcggc gaacacactg tttatggatt
    16501 gaaagaagac ggtgttggtc taacagaagg acaactttct gacgaagcga aaaaagcagt
    16561 tgatgaagca aaagaaaaaa tcatttcagg tgacgtaaaa gttccagaaa ctcctgaaga
    16621 aaactaaaac catttctata gccttgttag acacatgttt gacaaggcta tggtttgatt
    16681 agaacaagaa ttgttcattt atccaagctg ccttgtgaca gtttggataa gggaacaact
    16741 ccctgaagta atgtttgttt caaaagaaga acgctcacta agcgtgaatc ttagtcaatc
    16801 gttgccctag atagaaatcg ttaggatgtg aaaaaaaggt ggttcaagaa aatattgtca
    16861 tagaaatgca gaatattacc aaagaatttg gaacattcaa ggcaaatgac aacatcaatt
    16921 tacaagtaaa ggcaggagaa attcatgcgt tgcttggaga aaacggtgct ggcaaatcta
    16981 cattgatgaa cgtgctttcc ggattattag agccgacatc agggaaaatt ttgatgcgtg
    17041 ggaaagaagt aaagatcaca agtccgacca aagccaacca attagggatt gggatggtcc
    17101 atcagcactt tatgcttgtt gatgccttta ctgtaacaga aaacatcgtg ttgggaagcg
    17161 agcctagtcg cgcagggatg cttgaccata aaaaagcacg aaaagagatc caaaaagttt
    17221 ctgaacagta tggattgtca gtcaacccag atgcttacgt tcgtgatatt tcagttggaa
    17281 tggaacaacg ggtagaaatt ttaaaaacac tttaccgagg agcagatgta ctgatttttg
    17341 atgagccgac agctgtattg acccctcaag aaattgatga attaatcgtg atcatgaagg
    17401 aattagtcaa agaaggcaag tcgatcattt tgattacgca taagttagat gaaatcaaag
    17461 cagtagctga ccgctgtaca gttatccgcc gtggaaaagg aatcggtaca gtcaacgtta
    17521 aagacgtaac ctcacaacaa ttagccgata tgatggttgg aagaacggtt tcattcaaaa
    17581 cgatgaaaaa agaagcgaag cctcaagaag tcgttttgtc tattgaaaat ctagtggtga
    17641 aagaaaatcg tggattagaa gccgtgaaaa acttgaactt agaggttcgt gctggcgaag
    17701 tacttggtat cgctggaatc gatggaaacg ggcagtcgga gttgatccaa gctttgactg
    17761 gtttgcgaaa ggcagaaagc ggacatatca agctaaaagg ggaagacatc actaataaaa
    17821 aaccccgaaa aatcactgaa catggtgtag gacacgtgcc agaagaccgt cataaatacg
    17881 ggttagtcct agatatgaca ttatctgaaa atatcgcact acaaacctat catcaaaaac
    17941 cttacagtaa aaacggcatg ctgaattatt cagtaatgaa tgaacatgcc agagaattga
    18001 tcgaagaata tgatgttcga acaacgaatg aacttgttcc cgcaaaagct ttatcaggcg
    18061 gaaatcagca aaaagcaatt atcgctcgtg aagtcgaccg agatcctgat ctgttgattg
    18121 ttgcaaatcc aactcgtgga ctggatgtag gtgcgatcga atttattcat aaacgtctga
    18181 tcgaacaaag ggacaaatac aaagcagtgt tactgatcag tttcgaatta gaagaaattt
    18241 taaatgtttc ggatcgtatt gctgttatcc atgaaggaga aattgtcggt atcgttgatc
    18301 cgaaagaaac atctgaaaat gaattaggtc tattgatggc gggctatacc ttagaagaag
    18361 cacgaaaaga gttagaaaag ggggctggcg cacatgaatg atcgcagcga aaaattccgt
    18421 aatttattag tgcctgtact ttcagttgtt ttaggattga tcttaggcgc gatattgatg
    18481 gctgcttttg gttttcagcc catccaaggt tattcttcta tgctagatgc agcccttggt
    18541 tcgcaaagag ggataggtga aacgttaagg caagcaacgc cgttgatttt tacagcatta
    18601 ggtttttctg tagctaactc agctgggttt ttcaatattg ggctttctgg acaagcactt
    18661 tgcgggtgga tcgtcagtgt ctgggtggca cttgcgtttc cagatctgcc aaaagttgtt
    18721 ttgcttccgt tatgcgtgat cttaggtgcc ttagctggtg cgatggcagc ggctgttcca
    18781 ggtttacttc gagcattttt tggaacaagt gaagtgatcg taacaatcat gatgaactat
    18841 atcttattat acgtaagcac atttgcttta catgaagtga tgcctgaaag ctatcgctca
    18901 agtttggact cttccaatat gatcagtcaa aatgcctcac tgcggttacc atggttaaca
    18961 caagcttttg gcggctctcg cgtaaactca ggattatttt tagcaatcat cgcgcttatt
    19021 ttcgtttggc tgctgatgaa gaaaacgact ttaggatttg aaatccgttc tgttggattg
    19081 aatccttttg cttctgagta tgcaggaatg agtagtaaac gtacgatcgt tttgtcgatg
    19141 gtcatttctg gcgctttggc agggcttggc ggtgtggttg aaggattagg aacgtatcaa
    19201 aacttctttg ttcaaacgac ttcgctatct attggatttg acggaatggc tgtttccttg
    19261 cttggttctg gatcagcaat cggtattctt ttatcagcga tcttgttcag tattttgaag
    19321 atcggtggac ttggcatgca gacaggagca ggtgttccgt ttgagatcgt caatgtatcg
    19381 attgctttga ttatcttctt tgtcgggatc aacttcctga ttcgtttcgt catggctaaa
    19441 gtcttccaag ggaaaaaaca agaagagatc gttgcgacaa tagaatcgaa accaacgaat
    19501 caaaaccatg aagggggcga actataatgt cgactatcga attaattgcc ttgatcctta
    19561 cttctacact ggtttattca acaccgctaa ttctaacgtc actaggcgga actttttctg
    19621 aacgaagcgg gatcgtaaac gtagggctag agggaatcat ggtcatgggt gcttttagtt
    19681 ccatcgtttt caacttgacg atgagtccat cacttggttc tatgacacca tggatcgcta
    19741 ttttagtggg tggcgtcgta ggtatcctat tttctctgat tcacgcagta gcaacagtca
    19801 gtttgcgtgc tgaccatatt atcagcggga cagtaattaa tctgatggca cctgctttag
    19861 gtgttttctt gatcaaagca tggtatggta aaggtcaaac tgataacatc acgcagaatc
    19921 tggggtattt ttctttccca ggattagcag atattccggt cattggacca attttcttta
    19981 aaaatacatt cttacctgct tattgtgcta ttttgattgc tgtcctagct tgggtgatca
    20041 tcttcaagac gaaattcggc ttgcgcctcc gttcagttgg tgaaaatcct caagctgccg
    20101 acacattagg tatcaatgta tatgctatgc gttattcagg cgtactgatt tctggcttgt
    20161 taggcggtat gggcggtgct gtttttgctc agtcgatttc cggtaacttt tcagctggta
    20221 cgatcgttgg acaagggttc atctccatgg ctgctatgat ctttggtaag tggaatcctt
    20281 taggggcaat gggtgcctca ttgttctttg gttttgctca aagcttgagt atcattggcg
    20341 cacaattacc agttatttct tcgattccgc cagtattgct gcaaattgct ccatatttgc
    20401 tgacaatcat tgtgctggtt gttttcttag ggaaagcttc tggtccaaaa gcaaacggga
    20461 agaactatat caaatcaaaa taatctttta gcgaataaaa agggtgggtt acgggaagtg
    20521 tttttcgtct cgcccttttt gttttaaagg caataaaaat aaaaagaaag aaggaataat
    20581 catgtttaaa cgcgtacatc tgatcgtcat ggattcagta ggaattggag aagcaccaga
    20641 tgccgataag ttcggtgatg ttggttctga tacattagga cacattgcga aagaagcagg
    20701 attgaacgtt ccacatttag agcagcttgg tttaggaacg atccgtcctc ttgaaggtgt
    20761 ggaatcagtg aaagatcatc aaggctatgc gacgaaatta gaagaagttt ctgtagggaa
    20821 agatacgatg acaggccact gggaaatcat gggattgaat atcaaaactc catttcgtgt
    20881 gtttcctaat ggattccctg atgatctgat caaacaaatc gaagaatttt ctggccgtaa
    20941 agtcgtatgt aacaaacctt atagcggaac agctgttatt gacgattacg gtgaacacca
    21001 aatgaaaaca ggcgatttaa ttgtatatac ttctgccgat cctgtccttc agatcgcggc
    21061 acatgaagaa atcattcctt tagaagaatt atatcggatt tgccaattcg ttcgtgatat
    21121 aacaaaagat gatccgtata tgattggccg aatcattgca cgtccgtacg tgggtgaacc
    21181 aggagacttc acacgaacaa gcaatcgcca tgattatgcg ttgaatccat tcggacacac
    21241 agtccttgat tctttgaaag aagcaggaaa ggacgtgatt gctgttggaa agatcaacga
    21301 tattttcaac ggacaaggaa tcactgaatc tgtccgcacg aaaagcaata tggatggcgt
    21361 tgaccagctg ctgaaagtta tgaaaaacga tttttcagga atcagcttta ccaatttagt
    21421 agattttgat gcattatacg gtcatcgtcg ggatgtagtc ggctatgcgc atgcgattga
    21481 agaatttgac ttacgaattc cagaattgct tgaagcgatg gaagaagacg acttgctaat
    21541 gattacagcc gatcacggaa acgatccgac gtttactggt accgatcata cgcgagaata
    21601 tgtaccgtta ttggtttaca gtaaaaaaat gaaagaacaa ggggcattgc ctcaaggata
    21661 ttattcagat atttcagcaa cgattgctga gaactttagt gtttcttcga ctgaaaatgg
    21721 cgaaagcttc ttgaaattat taaaataatc tttttaaata ggagaaagca aatgaccaag
    21781 ttaagcgaga tgttacaaga aacgacccag tttatccttg ataaaggagt aaaagaaatt
    21841 gattttggtt tgattctagg ttcaggatta ggtgaattag cagatgaaat cgaagatgct
    21901 gtaatgattt cttatgatga gatcccgttc tttcctgttt cgacagtagt tgggcatgca
    21961 ggaaagctag tttatgggtc tctggcaggc aagaaagtgt tagccatgca agggagattc
    22021 cactactatg aaggtcattc catgcaaaca gtgacctatc cagtacgtgt gatggccgga
    22081 ctaggggccc attcagtcat tgtgactaat gcatgtggtg gtgtcaacga atcatttgta
    22141 ccaggagatt tgatgctgat taccgatcat atcaatttta ctggtgaaaa tcctttgatc
    22201 ggtccgaatg aagatgcaat gggccctaga tttccagata tgagtcaagc ttatacgcct
    22261 gactatcaag caacagcaaa agcagcagca gaaaaactag gtttggatct taaagaaggc
    22321 gtatatatgg gctattctgg accaacttat gaaacgcctg cggagatccg aatgtctcgg
    22381 acaataggag ccgatgcagt agggatgtcg actgttccag aagtcatcgt agcagctcac
    22441 agcggattaa aagtgttagg aatctcttgt attaccaact tagcagcagg tatgcaagcg
    22501 aatctgagcc atgaagaagt tgtagaaaca actcagagag tcaaacaatc ttttaaagca
    22561 ttggttaaag aaacattgac attattgtaa taggaggaac aataaaatga gtgtgcatat
    22621 tgaagcgaaa gaaggcgaga tcgccgataa gattttactt ccgggagatc ctttgcgagc
    22681 taaatatatt gcggagactt ttttggaaga tccagtttgt tacaatcagg tacgcggtat
    22741 gttaggcttt accggcaaat ataaaggaga acgtatttct gttcaaggaa caggaatggg
    22801 aatgccatca gccaccatct atgcccatga attgatccag tcgtatggtg taaagaaatt
    22861 gattcgagta ggtacatgcg gtgcattgtc aaaagacgtc catgttcgtg atttagtact
    22921 agcacaaggt gcagcgacca gttcttcgat gatcgaaaaa aatttccaag cctttcattt
    22981 tcctccaatc agtgatttca atctattact gaaagcatat gagatagcta aagaaaaggg
    23041 ctatacggtt catgtaggaa atgttctttc ggaagattct ttctacaaag atgatttgac
    23101 agagacgttc caattagctg aacttggcgt tttaggagtg gaaatggaag cagcggctct
    23161 ttattactta ggcgcgaaat accatgtgca gacattaagt ttgatgaccg ttagcgacca
    23221 tttgatcacc ggtgaagaaa caacagctgc agaacgtcaa tctacgttca atgaaatgat
    23281 cgaagtagga ttggaaacag cgatagcaga ataagaagga aatgaaaaag ctgccctgca
    23341 ttaagtaata agaacatcca agcaaaaata gctcctcatg tttttgactt ggctggactt
    23401 attattgcaa atgtaagctt ttgaacaccg tttaccaaga ggttgtgaat ctgccgttta
    23461 actctgagtc acaaggaaca atttcaaaaa acagcttttc atgtttgatg aatattgtga
    23521 cttgtgaccg agaagttggc aggagaaaac cgtttatacg aaaaaaggga ctgtgacaaa
    23581 tcgtgtcaca gtcccttttt tatagtgttt tttataggta gtatttttta gcaactgtta
    23641 agtcatcatt taattcataa acaagtggtt gacctgttgg aatttcaaga tccatgatgt
    23701 cttcgtcaga gataccttcg atatgtttag ctagggcgcg taatgagtta ccatgtgcag
    23761 ctactaaaac agttttgttg tctagtaatg ctggagcaat ttcatcttgc cagaatggca
    23821 aagcgcgttc taatgtcact ttcaagtttt ctccaccagg aatatcgcgt ttgtctaaca
    23881 ttgcgtaacg acggtcattt gctgcagaac cttcgtcagt ttcttccatt aatggaggaa
    23941 gagtatcgta agaacgacgc cagatgtgca cttgttcgtc gccgtatttt tcagctgttt
    24001 cttttttgtt caaaccttgt aatttaccat agtgacgttc gtttaagcgc catgatttga
    24061 tttgtggtac ccaaagttga tctgaatatt ctaagatcaa gttacatgtt ttgattgcac
    24121 gagttaaaac agaagtgtaa gcaacatcaa attcgattcc agcttctttg attttgcgtc
    24181 cgccttcttt tgcttcttcg attccttctg gtgctagatt tacatcagcc caaccagtaa
    24241 attggttcaa tgcattccat tcactaagac cgtgacgaga aaaaactaat tttggcatgt
    24301 ttagctctcc ttttaagata ggtttatatt tctgaaattt tcagttctgt tttattgtac
    24361 aattttttgg aagagatttc catcgaaaaa ttagataaga ttctatgaga aaacaagtag
    24421 agaatataaa aaaacgaaca gtgcccacgc aactgttcgt ttttaggtat tagatgcata
    24481 attgctcgat ttctttttca ggtaaattga tatatttata acatgttcca actgaaacac
    24541 cgcattttga agaaataaat tggatcgttt cttttttttc ataatagaga cgtcggattt
    24601 ttttgatcgt ttttgcatcg atttttggtc ttccgccgat ttttcctttt ttacgagctt
    24661 catctaatcc aactaatgta cgttctttga tcaatgcgca ctccatgttt gctaggtttt
    24721 ccattaattg gaaatagatt tttcccattt cgcgcgtatc gattccttca tcaagactaa
    24781 tcaagtgcag cccgcgatct ttgaataatt gcgtgagttc tgttaattgc cgcgtagatt
    24841 tgcctaatcg atgaagttgg caaatgacta gtgcatcgcc ttgttgcatg tcagcgatca
    24901 ctgactccaa atgaacagca gtagaatcat tttgttccac ttcatatgtc tcatggaaaa
    24961 tttcttgaca accaaagtca gataattgat caacctgagt tgttaaatca acgtcattta
    25021 tggttgtgcg tgcataacca ataattttca tggtgattcc tttctagcag tgattttcta
    25081 actggatata acagtaaaaa tgtagcataa agtacgtcaa aaagatagtt ttttcgcaaa
    25141 ttttccgctg tcttttttta ttggatgatc aagcagtttt tctttattta cgacggattg
    25201 cgtcaagaat ctcaacgcct ttttctgagc cgacaactac tttagaaacc atgtttagga
    25261 aaagcccatg ttctactacc ccaacaagtt catctaaata ggtagctaag ctttctggct
    25321 gttcgatgac ttctagatgc agatcaatga tgtaatgacc accatctgtg gttaagactt
    25381 ctccgttttc gtctgtacgc aagacgggtt ggaatctttt ttcttcaaaa atatgaagta
    25441 gctgttggga gccataaggg atcacttcaa ctgggagtgg gaacttccca agtttatcga
    25501 ctaatttaga agaatcaacg atccaaatcg tttcttttga gtacgtagcg actattttct
    25561 cgaaaagcaa agcagcgccg ccgcctttga tcccttgaaa atcagcactg atttcatcag
    25621 caccgtctat tgtcaaatcg actacgggga cttcatcaat actctttaac ggtattccta
    25681 atttttccgc ttgttctttt gtcgcatttg aagtagtaac tcctgtgata cgtaaacctt
    25741 cttcacgcat acggcgacca atctcttcta ccatataata ggcggttgaa ccggtcccga
    25801 gacctacgat catcccgtcc tttacgaatt tcgcggcttc aatgccagct aattgtttta
    25861 aattcatctt tgcgtccacc tttttttagt ttgagcatcg tgctttcctc actattttag
    25921 cgtgatttac ggtaaaaaga taccattctt ttttattcca ataaagcttt ttcaaaaaaa
    25981 attgcatctc ttgttgacat gttttttcat tcgtgatatt ctaacaaagg tgctttatct
    26041 acaggtttct gtgaagaaac gtgctgactg tttatcaaag catatttgat aaggatgcag
    26101 acattgcatt tattttttat cacaaaaaaa gaaccacctg gatgtgtgga actagacgca
    26161 aatcgtggga aggaggaaac aaggaatgcc tacaattaac caattagtac gtaaacctcg
    26221 taaatcaaag gtggaaaaat ctaattcacc tgctttgaac aaaggatata acagctttaa
    26281 gaaaactcaa actaacgtaa actcacctca aaaacgtggg gtagcaactc gtgtgggtac
    26341 aatgacacct aaaaaaccga actcagcttt acgtaaatat gcacgtgttc gtttgtcaaa
    26401 cttaattgaa gttactgctt atatcccagg gattggtcat aacttacaag aacacagtgt
    26461 tgtattatta cgcggtggtc gtgtaaaaga cttaccaggg gtacgttacc atatcgttcg
    26521 cggtgcttta gatactgctg gtgttaacga ccgtaaacaa agccgttcta aatacggaac
    26581 taaaaaacct aaagcttaat tttaattatt aaacaaatga aacttgcttc tactatatag
    26641 aagtaattac tatgaacaat atttcggaag gaggagttac ggatgccacg taaaggtcct
    26701 gttgcaaaac gtgatgtttt accagatcct atttataact caaaattagt aactcgcttg
    26761 atcaaccgtg taatggttga cggaaaacgc gggattgcag ctaacattat ctataatgcc
    26821 tttgacttga tcaaagaatc tacaggtaac gatccattag aagtgtttga acaagcaatg
    26881 aaaaacgttc aacctgttct tgaagttaaa gcacgtcgtg ttgggggttc aaactaccaa
    26941 gtaccagttg aagttcgccc tgaacgccgc gttactctag gtcttcgttg ggtagtaaac
    27001 tacgctcgct tgcgcggtga acacacaatg gaagaacgct tagcaaaaga aatcatggat
    27061 gctgcaaaca acacaggtgc ttctgttaaa aaacgtgaag acactcataa aatggctgat
    27121 gccaaccgtg cgtttgctca ctatcgctgg taagattctc tctgtttggt cggcttttat
    27181 aagtcgacct cagatagtgt ccttattttt agcaactaga tagtaaagag aggagaaaca
    27241 aggagaatga ccagagaatt ttctttacaa aacactcgta atatcggtat catggcccac
    27301 atcgatgctg gtaaaacgac tgctactgaa cgtatcttgt actatactgg taaaatccat
    27361 aaaattggtg aaactcatga aggagcttca caaatggact ggatggaaca agaacaagaa
    27421 cgtggtatta cgatcacttc tgctgctact acagcacaat ggaagggtca ccgaatcaac
    27481 atcatcgaca caccaggaca cgtagacttc acagttgaag ttgaacgttc attgcgtgta
    27541 cttgatggtg ctgtaactgt tcttgatgca caatcaggtg ttgaacctca aactgaaaca
    27601 gtttggcgtc aagcaacaac ttatggtgta cctcgtatcg tatttgcaaa caaaatggac
    27661 aagatcggtg ctgacttctt atattcagta tcaactttac atgaccgttt gcaagcaaac
    27721 gctcacccaa tccaattacc aattggtgcg gaagacgact tcacaggaat tatcgacctt
    27781 gtaacaatga aggctgaaat gtatacaaac gatcttggaa cagagatcga agaaacagaa
    27841 attcctgaag aataccgcga attagctgaa gaatggcgcg aaaaattggt tgaagctgta
    27901 gctgaaactg atgaagaact tactttgaaa tacttagaag gtgaagaaat cactgaagct
    27961 gagttaaaag aaggtatccg ccgcgcaaca gttaacgtag aattctaccc agtactatgt
    28021 ggttcagcat ttaagaacaa aggggttcaa ttactattgg acgctgttct tgattacttg
    28081 ccatcaccgt tagatatccc agctatcaaa gggattgacc ctaaaactga tgaagaagta
    28141 gaacgtcctg cagacgacag cgctcctttc tcagctttag catttaaagt tatgactgac
    28201 ccattcgtag gtcgtttaac tttcttccgt gtgtactctg gtgttttaca atcaggttca
    28261 tacgtacaaa acgcaacaaa aggcaaacgt gaacgtgttg gtcgtatcct acagatgcat
    28321 gccaactctc gttcagaaat ctctgaagtt tacgctggag atatcgctgc tgctgttggt
    28381 ttgaaagaca caactactgg ggacacacta tgtgatgaaa agagtctagt tattcttgaa
    28441 tccatggaat tcccagaacc agttatccaa gtcgctattg aacctaaatc aaaagctgac
    28501 caagataaaa tgggtgtggc tttacaaaaa ctatctgaag aagatcctac tttccgtgct
    28561 gaaacaaacg tggaaacagg cgaaacaatc atcgctggta tgggtgaact tcacttagat
    28621 atcatcgttg accgtatgcg tcgtgaattc aaagttgaag ctaacgtagg tgcgcctcaa
    28681 gtatcttacc gtgaaacttt ccgtgctggc actcaagccg aaggtaagtt tgtacgtcag
    28741 tctggtggta aaggtcaata cggtcacgta tggattgaat ttacaccaaa tgaagaaggt
    28801 gctggtttcg aatttgaaaa tgcgatcgtc ggtggggttg ttcctcgtga atacattcca
    28861 gctgttgaaa ctggtttgaa agatgctatg gaaaatggtg tcttagctgg ctatccatta
    28921 gtagatatca aagctaaact ttacgatggt tcataccatg atgtcgattc aaatgaaact
    28981 gccttccgtg ttgctgcttc tatggcatta cgtgcagcag ctaagaaagc taatccagta
    29041 atccttgaac caatcatggc tgtagaagtt gttatccctg aagattattt aggtgatgtt
    29101 atgggtcacg taactgctcg tcgtggacgt gttgaaggta tggaagctcg cgctggcggc
    29161 caacaagttg ttcgtgcgat ggttccactt gctgaaatgt ttggttatgc tacaactctt
    29221 cgttctgcta ctcaaggtcg tggtacattt acaatgacat ttgaccacta cgaagatgta
    29281 ccaaaatcag tacaagaaga aatcattaag aaaaacggcg gaaaagctga ataatttctt
    29341 gaaaccggat agtcctgcaa agagattatc caaagagact atatttttaa tatagtttcg
    29401 tgtaaaataa ttatcgatga tatgggcatg tggtgtacct tgtgtacatc atatacctat
    29461 cagacaaata aaaaatatat tgtattttta ggaggacatt ttaaaatggc aaaagaaaaa
    29521 tttgaccgtt ctaaaccaca cgttaacatt ggtactatcg gacacgttga ccatggtaaa
    29581 actacattaa cagctgcaat cacaactgta ctatctaaga aaaacggcgg ccaagctatg
    29641 gcttacgatc aaatcgatgg tgctccagaa gaacgcgaac gcggaatcac aatctcaaca
    29701 gctcacgttg agtatgaaac agatacacgc cactacgctc acgttgactg cccaggacac
    29761 gcggattacg ttaaaaacat gatcactggt gctgctcaaa tggacggagc tatcttggta
    29821 gtttctgctg ctgacggccc aatgcctcaa actcgtgaac acatcctatt gtctcgtcaa
    29881 gttggtgttc cttacatcgt tgtattcttg aacaaagtag acatggttga tgacgaagaa
    29941 ttactagaat tagttgaaat ggaagttcgt gacctattaa cagaatacga attccctggt
    30001 gacgatgttc ctgtagttgc tggatcagct ttgaaagctc tagaaggcga cgcttcatac
    30061 gaagaaaaaa ttcttgaatt aatggctgca gttgacgaat acatcccaac tccagaacgt
    30121 gacaacgaca aaccattcat gatgccagtt gaagacgtgt tctcaattac tggacgtggt
    30181 actgttgcta caggtcgtgt tgaacgtgga caagttcgcg ttggtgacga agttgaagtt
    30241 gttggtattg ctgaagaaac ttcaaaaaca acagttactg gtgttgaaat gttccgtaaa
    30301 ttgttagact acgctgaagc tggagacaac attggtgctt tactacgtgg tgttgcacgt
    30361 gaagacatcc aacgtggaca agttttagct aaaccaggta caatcacacc tcatacaaaa
    30421 ttctctgcag aagtatacgt gttgacaaaa gaagaaggtg gacgtcatac tccattcttc
    30481 actaactacc gtccacaatt ctacttccgt acaactgacg taacaggtgt tgttgaatta
    30541 ccagaaggaa ctgaaatggt tatgcctggc gacaacgtaa caatggaagt tgaattaatc
    30601 cacccaatcg ctatcgaaaa cggtactaaa ttctcaatcc gtgaaggcgg acgtacagtt
    30661 ggtgccggtg tcgttacaga aatcaaagct taattcactt aagttttaaa gtaaagcaac
    30721 atttattcgg acgtaatcgc tcggaacgaa ggtcttagga tctttgttcc gagctttttt
    30781 atttattgca ggatcaggaa aaaagacagg agtattataa atagaagaaa cacgaaataa
    30841 aagagtcagt attttctaaa tgaaacttta tgaaaacaaa atgtttttta caagaaaaag
    30901 ccttgctttg tgagtttata tatattataa tgacaaaggt gcgtttactt tagtgaattg
    30961 cacagacgta atcagaatga tttcgtcggc taagaaacga gaggttgcga cacgcccgga
    31021 cgctttgcca cgaacgagcg tgacggaaat tttcgtggag ctatgtctac ttttcaaaat
    31081 aggcgaagga gggaacaaga tggcaaaaca aaaaattcgt atccgtttaa aagcgtatga
    31141 acaccgtatt ttagatcaat cagcggataa aatcgtggaa actgcaaaaa gaactggagc
    31201 tagcgtgtct ggtccaattc cattaccaac tgaacgcagt ctttacacaa tcatccgtgc
    31261 gactcataaa tacaaagatt cacgcgaaca attcgaaatg cgtacacaca aacgtcttat
    31321 cgacattgtg aacccaacac caaaaactgt tgatgctttg atgaagctag acttaccatc
    31381 tggtgtaaac atcgaaatca aattataaaa ctaaaacaaa aataatggag gtgtactcat
    31441 gaccaaagga atcttaggga aaaaagtggg aatgacacaa atcttcactg aatctggtga
    31501 attaattcca gtaactgttg tagaagctac tccaaacgta gtactacaag tgaaaacaat
    31561 ggaaacggat ggctacgaag ctattcaagt tggttaccaa gatatgcgtg aagttttatc
    31621 aaacaaacct gcgaaaggtc atgttgcaaa agcaaacacg gctcctaagc gcttcattcg
    31681 tgaattcaaa aatgttgagc taggagaata tgaagtagga aaagaaatta cagtagatgt
    31741 tttccaagca ggagacatta ttgatgtaac aggtactacg aaaggtaaag gattccaagg
    31801 ggttatcaaa cgccacggac aaagccgcgg accaatggct cacggttctc gttaccatcg
    31861 tcgtcctggg tcaatgggtc cagttgcacc taaccgtgta tttaaaaaca aacgtcttgc
    31921 tggccgtatg ggtggcaacc gcgtaactat ccaaaacttg gaagttgtac gtgtcgatgc
    31981 agaaagaaat gttatcttga tcaaaggtaa tgttcctgga gctaaaaaat ctttaattac
    32041 tatcaaatca gctgtgaaag ctaaataatt gtaggaagaa aggaggaact aaggaatgcc
    32101 gaatgtagca ttattcaaac aagatggaag ccaaaacggt gaaatcacac ttaacgaaga
    32161 aatcttcgga attgaaccta atgaaagtgt tgtttacgat gcaatcgtaa tgcaacgtgc
    32221 gtcattaaga caaggaacac acgcggttaa aaaccgtagc gctgttcgcg gcggcggacg
    32281 taaaccatgg cgtcaaaaag gaacaggtcg tgcacgtcaa ggatctatcc gctcaccaca
    32341 atggcgtgga ggtggcgtag tctttggacc aacaccacgt tcttacagct acaaacttcc
    32401 taaaaaagtt cgtcgtttag caatgaaatc tgtattgtca gaaaaagttg ctgaaaacaa
    32461 cttggtagca atcgaaggct tgaacttcga cgcaccaaaa acaaaagaat tcaaacaagt
    32521 tcttgctaac ttatctatcg actctaaagt attggttgtt ctagaaaaag gtaacgactt
    32581 tgctgcttta tcagcacgta acttaccaaa cgtttctgta gtaacttctg ataatgtgag
    32641 tgtgctagac gttgtatcaa atacaaaagt gttagcaaca caaactgctc ttactcaaat
    32701 tgaggaggtg cttgcataat gaacttacta gacgtaatca aacgcccagt gatcactgaa
    32761 aaatcaatgc ttgccatgga tgacaagaaa tacacttttg aagtggacac tcgcgcaaac
    32821 aaaactttag taaaacaagc ggtagaagct gcttttgacg ttaaagtcaa aaacgtgaac
    32881 atcgtgaacg tacgtgcgaa attcaaacgt atgggcaaat atgcaggata tacaaaaaaa
    32941 cgtcgcaaag cgatcgttac attgactgaa gattcaaaag aaatccaatt attcgaagct
    33001 gctgaataag cactaataga taactcatta aattaggagg gaaaaacgtg gcgattaaaa
    33061 agtacaaacc tacctcaaat ggtcgtcgta acatgacagg ttctgatttt gctgaaatca
    33121 caacatcaac acctgaaaaa tcattgttac aaccattgaa aaaccatgct ggacgtaaca
    33181 acaacggccg catcactgta cgtcatcaag gtggcggaca caaacgccaa tatcgcgtga
    33241 tcgacttcaa acgtaacaaa gataacgttg ttgcaactgt tcaaacgatc gaatatgatc
    33301 caaaccgttc agctaacatc gcgttagtac actatgaaga tggagtgaaa gcttacatct
    33361 tagcacctaa aggactagaa gtgggtatga aacttgtttc aggtccagaa gcagatatca
    33421 aagtcggaaa tgctcttcca ttagaaaaca ttccagttgg tactgttatc cacaacattg
    33481 aaatgaaacc tggtaaaggt ggacaattga tccgttctgc tggtacaagt gctcaagtac
    33541 ttggtaaaga aggcaaatac gtattgatcc gcttgaactc tggtgaagtt cgtatgatct
    33601 tagctgcatg ccgtgctaca atcggttctg taggtaacga acaacacgaa ttaatcaaca
    33661 tcggtaaagc tggacgctct cgttggatgc gtaaacgccc aactgtacgt ggtagcgtaa
    33721 tgaaccctaa tgatcaccca cacggtggtg gtgaaggtaa agctcctatc ggacgtaaag
    33781 caccagtttc tccttggggt caaccagctc ttggttacaa aactcgtaac aaaaaagcta
    33841 aatcagacaa acttattgtt cgtcgtcgca aaaataaata attactttga ccatgtgtcg
    33901 cacattttga gaggaggttc accatgggtc gtagtttaaa gaaaggacct tttgtcgatg
    33961 agcatttaat gaaaaaagtt gaagctcaag caggggttga aaagaaaaaa gttatcaaaa
    34021 cttggtcacg ccgttcaaca gttttcccaa gttttgttgg atataccatc gcagtttatg
    34081 atggacgtaa acatgtacca gtttacatcc aagaagacat ggtaggacac aaattaggtg
    34141 aatttgcacc tacaagaact tatcgtggac atgctgctga cgataagaaa acgaaacgct
    34201 aatttgaggg gaggataaat ccaaatggca gaacaaatca catcagctaa agcaactgca
    34261 aaaacagttc gcacttcacc tcgaaaagcc cgtttagtaa ttgaccttat cagaggtaaa
    34321 agtgtcgcag atgcaatttc aatcttgaaa ttcacaccaa acaaatctgc tggaatcatt
    34381 gaaaaagtat tgatgtcagc agttgcgaat gcagaaaata actttgactt agatgttgaa
    34441 aacttggtag taagcgaagc ttttgttaac gaaggaccta caatgaaacg tttccgtcct
    34501 cgtgcaaaag gatcagcttc tccaatcaac aaacgtacaa gtcatatcac ggtagtcgta
    34561 tcagaaaaat aaggagggat aatcagtggg tcaaaaagta catccaattg gaatgcgtgt
    34621 aggcatcatc cgcgactggg atgctaaatg gtatgctgaa aaagagtatg ctgagttctt
    34681 acacgaagat ttaagaatcc gtaaatttat ttcaactaaa cttgctgatg ctgctgtatc
    34741 aacagttgaa atcgaacgcg caacaggtcg cgtaaacatt tcaattcaca cagctaaacc
    34801 aggtatggtt attggtaaag gcggttctga agtcgaaagc ctaagaaaag aattaaacaa
    34861 attaactggt aaaagaatcc atatcaatat cgtggaaatc aaaaaaccag atctagatgc
    34921 aaaattagta ggtgaaggaa tcgcacgtca attagaaaac cgtgttgctt tccgtcgcgc
    34981 tcaaaaacaa gccatccaac gctcaatgcg tgctggcgct caagggatca aaactcaagt
    35041 atctggtcgt ctaaacggag cagatatcgc tcgttcagaa ggatactcag aaggaactgt
    35101 tcctcttcat actttacgtg cggacattga ttacgcatgg gaagaagcag atacaacata
    35161 cggaaaacta ggagttaaag tgtggatcta tcgtggagaa attcttccaa ctaaaaaaaa
    35221 cactgagaaa ggagggaaat aatcatgtta gtacctaaac gtgtaaaaca ccgtcgtgaa
    35281 ttccgcggaa aaatgcgcgg ggaagctaaa ggcggaaaag aagtagcatt cggtgaatac
    35341 ggtttgcaag ctgttgattc acattggatc acaaaccgcc aaatcgaagc tgctcgtatc
    35401 gcaatgactc gttacatgaa acgtggtggg aaagtatgga ttaaaatttt ccctcacaaa
    35461 tcttatactg ccaaagcaat tggggtacgt atgggttctg gtaaaggggc acctgaagga
    35521 tgggttgcac cagtaaaacg tggtaaaatc atgtttgaaa tcgcaggcgt tcctgaagaa
    35581 gtagctcgtg aagcgttacg tctagcttct cacaaattac caatgaaaac taagatcgta
    35641 aaacgtgagg aaatgggtgg tgaatcgaat gaaggttaaa gaaatcagag aattaaccac
    35701 tgccgaaatg cttgatcaag aaaaacaatt aaaagaagaa ttgtttaatc ttagattcca
    35761 attagcaaca ggtcaattag aaaacactgc acgtattaaa gaagtacgta aatcgattgc
    35821 acgcatcaaa actgtgttgc gtgaacaagc taagtaatta tggaaggagg ccattaagcg
    35881 tatgactgaa ggaagaaatc aacgcaaagt ttatcaaggt cgcgtggttt cagacaaaat
    35941 ggataaaaca attaccgttg ctgtcgaaac aaagaaaaac caccctatct atggcaaacg
    36001 catgaactat tctaagaaat acaaagtgca tgatgaaaac aacacagcaa aagttggcga
    36061 catcgtgaga attatggaaa ctcgtccatt atcagctaca aaacgtttcc gtttgttgga
    36121 agtagtcgaa gaagcagtta ttatctaata acacgagatt ttcctatata gattgaatgc
    36181 aaaatctgaa aggaggatac acaacgtgat ccaagcagaa agtcgtttaa aagtcgctga
    36241 taactcaggc gcacgtgaaa ttttgacgat caaagtcctt ggtggatctg gtcgtaaaac
    36301 tgctaacatc ggtgatgtga tcgttgctac ggttaaacaa gcaacgccag gtggggttgt
    36361 caaaaaaggt gacgtcgtta aagccgttat cgttcgaaca aaatcaggag ctcgtcgtac
    36421 agacggttca tatattaaat ttgatgaaaa tgctgcagtg attattcgtg atgataaaag
    36481 ccctcgtgga acacgtatct ttgggccagt tgcacgtgaa ctacgtgaaa acaacttcat
    36541 gaagatcgtt tcactagcac cagaagtttt ataatcttga gacacttatc aaaggaggtg
    36601 cgaaacagtt atgtttgtta aaaaaggcga taaagttaaa gttatcactg gaaaagacaa
    36661 aaacaaagaa ggcgttgtac tagcagcgtt cccgaaaaaa gataaagtta ttgtcgaagg
    36721 tgtaaatgtc gttaaaaaac accaaaaacc ttctcaagct gctcctcaag gtggaattgt
    36781 tgagatggaa gcgccaattc atgtttctaa cgtgatggtg gttgactcta ctggtgtagc
    36841 tggccgagtt ggctacaaag aagtagacgg caaaaaagtc cgtgtttcta aaaaaaccgg
    36901 tgaagtttta gataaataaa agtttaagga aggagggtct tactgaatga accgcctaaa
    36961 agaaaaatat cttaaagaag taactccatc attgatggaa aaatttaact atagctctgt
    37021 tatgcaaaca cctaaagttg aaaaaatcgt catcaacatg ggtgttggtg atgcggtatc
    37081 aaacgctaaa aacttagata aagcagttga agaattaact ttgatcactg gtcaaaaacc
    37141 aatgattaca aaagctaaaa aatcaatcgc tggattccgt ttacgtgaag gaatgccaat
    37201 tggtgcaaaa gttacattgc gcggagaaag aatgtacgaa ttcttagaca aattggtttc
    37261 tgtttcacta ccacgtgtac gtgacttcca tggtgtaagt aaaaaagcct ttgacggtcg
    37321 tggaaactat actttaggta ttaaagaaca attgatcttc ccagaagtag attatgattt
    37381 agtagataaa gtacgtggta tggacatcgt tattgtaaca acagcaaact ctgatgaaga
    37441 atctcgtgag ttgttgacac aattaggcat gccattccaa aaataattaa aggaggcgaa
    37501 ctacgtggct aaaaaatcaa tgattgctaa aaacaaacgt cctgcaaaat tttcaacaca
    37561 agcttatact cgttgcgaac gttgcggacg tccacattca gtttatcgta agttccatct
    37621 ttgccgtatt tgcttccgcg aacttgccta taaaggtcaa attcccggcg tgaagaaagc
    37681 tagctggtaa aaagtaaatt cgcataagaa ggaggtaaaa gatcaatggt catgacagat
    37741 ccaattgcag attttctaac tcgtatccgt aacgcaaaca tggttaaaca tgagtcttta
    37801 gaagtacctg catcaaaaat taaacgtgac atcgctgaaa tcttgaaacg tgaaggtttc
    37861 gttcgtgatg ttgaatacat cgaagatgac aaacaaggcg tgatccgtgt tttcctaaaa
    37921 tttggtaaaa acggcgaacg tgttatcaca aacttaaaac gtatctctaa accaggtttg
    37981 cgtgcttatg tcaaagctga cgaagtacca aaagtattga acggtttagg tatcgcaatc
    38041 atttcgactt ctgaaggtgt tgtcactgat aaagaagctc gtgaaaaaaa tatcggcggc
    38101 gaagttatcg cttacgtatg gtaatcaagt agaatctaca aggaggtgtc tttaagtgag
    38161 ccgtatcgga aataaagtcg ttgttatccc tgaaggagta acagttactc aagacggaaa
    38221 caacgttaca gttaaaggac caaaaggtga attgactcgt actttttcag cagatatcaa
    38281 aatgaatatc gaaggaaacg aagtaacttt cactcgtcca aacgacagta aagaaatgaa
    38341 aacaattcat ggaacaactc gtgcgaactt caacaacatg gttgtaggtg tcagcgaagg
    38401 tttccaaaaa gcgttagaac taatcggggt tgggtaccgt gcacaattac aaggatcaaa
    38461 acttgtattg aacgttggtt actcacatcc agtagaaatc acaccaccag ctggagtaac
    38521 tgttgaagta ccagctaaca cacaagtaat tgttaaaggt gcgaacaaag aagaagttgg
    38581 cgaattagct gcaaacattc gtggaactcg tcctccagaa ccttataaag gtaaaggtat
    38641 tcgttatgtt ggcgaatatg tacgccgtaa agaaggtaaa actggtaaat aatcgtttag
    38701 aaaaattgca tagaagccag cagcaggaaa aaggcatttg gctgaagttt accttcaaaa
    38761 aaatacattt ttacttgtgc cgcagcttct atttttcgaa acgtatttac tgcttgaaat
    38821 agtagtacaa taaaaataaa gaggtgacaa ttgtgattac aaaaccagat aagaacaaaa
    38881 cacgtcaaaa gagacatcgt cgtgtacgta acaatatctc tggtactgct gagcgcccac
    38941 gcttgaacgt ttttcgttct aacaaaaaca tctacgctca aattattgat gacgtagcgg
    39001 gtgtaacgct agcaagtgcc tctaccttgg ataaagaaat ttcaggtgga acaaaaacag
    39061 aagcagcaca agctgtcggt aaactagttg ctgaacgtgc agctgaaaaa ggcattaaag
    39121 tagtagtctt tgaccgtggt ggataccttt accatggccg tgtgcaagct ttagctgaag
    39181 ctgctcgcga aaatggacta gaattttaga agaaggagga ataccattca tggtttatat
    39241 cgatccaaaa catttggaat tagaagaccg cgttgttgca attaaccgtg taacaaaagt
    39301 tgttaaaggt ggacgtcgtc tacgttttgc tgctttagtt gttgtcggtg acaaaaacgg
    39361 acacgtagga tttggtacag gtaaagctca agaagttcct gaagcaatcc gtaaagcaat
    39421 tgaagatgcg aagaaaaact tagttgaagt acctatggtt ggttcaacaa tcccacacga
    39481 agtaatcggt gcttttagtg gtggtagaat cctaatgaaa cctgctgtag aaggttctgg
    39541 ggttgctgct ggtggaccag ttcgtgccgt attagaatta gctggggtag cagatatcac
    39601 ttctaaatct ttaggctcaa atacaccaat caacgttgtt cgcgcaacag ttgaaggttt
    39661 gaaacaattg aaacgtgcag aagaagttgc agaacttcgc ggcaaatcag ttgaagaatt
    39721 aatcggataa ggaggacaac aataatggct gaattaaaag ttactttaaa acgcagtatt
    39781 atcggacgtc ctcaaaacca acgcgataca gttaaagcgt taggtcttac aaagattaac
    39841 agttcagtgg ttaagccttc taatgaagca attaaaggca tgatcaatac tgtttctcac
    39901 ctagtggacg ttgaagaaat ttaatttaga aaaatcataa ctagaacatt aaggaggtgc
    39961 caaacctatg aaacttcatg aattaaaacc tgctgaaggt tcacgccaag tacgtaaccg
    40021 tgttggtcgt ggtacttcat ctggtaacgg aaaaactgcc ggacgcggac aaaaaggaca
    40081 aaaagctcgt tcaggcggcg gtgtgcgttt aggatttgaa gggggacaaa caccattgtt
    40141 ccgtcgttta ccaaaacgag gattcacaaa cgtgaaccgt aaagactatg cagtcattaa
    40201 tcttgatgta ttgaaccgct ttgaagacgg agctgaagta actcctgttg ctttagttga
    40261 agctggaatc gtgaaaaacg aaaaagctgg aatcaaagta ttagctaatg gggaactaaa
    40321 caagaaatta actgtgaaag cagcaaaatt ctctaaagca gctcaagaag caattgaagc
    40381 ggctggtgga tcaatcgagg tgatctaatg tttagactat taaaagatgc ttttaaagta
    40441 aaagacatta gatcgaaaat cctatttact gtatttgtgt tgtttgtatt tcgcctaggt
    40501 gcacatatta ctgtaccagg cgtaaatgct gcttcattgc aaaacctttc ttctttgcca
    40561 tttttcaaca tgttgaactt ggtaagtggt agtgcgatgc aaaacttttc cattttctca
    40621 atgggggttt caccatacat tactgcttct atcgtcattc agcttcttca aatggacatc
    40681 gtgcctcgat ttgttgaatg gtcgaaacaa ggggaagttg gtcgtaaaaa actgaatcaa
    40741 gcgactcgat atctgacatt agtattggca tttatccaat ctgtcggtat cactgctgga
    40801 ttcaatcaat acgctcaatt aggtttcgtg aataatccta acgtagcaac ttacgtaacg
    40861 atcggtttga ttctaacagc cggtacgatg tttgttactt ggctaggaga acagatcaca
    40921 gaaaaaggta tcggaaatgg cgtatcaatg atcatttttg caggtatcat ttctagattg
    40981 cctgaaagta tcagagaaat ttatgaagat tactttataa atattgatcc ttcagacata
    41041 tggaaatctg ctatttttgt ggccatttta ctagtagcgg tcttgttgat cgtgacattc
    41101 gtaacatttt tccaacaagc tgaacgcaag atcccgatcc aatatacgaa acgcgtagct
    41161 ggcgcgccta caagcagcta tctgccgttg aaagtaaatg cagctggagt tattccagtt
    41221 atctttgcta gttcgtttat tgctacgcca aatgctgttt tacaagcatt gagcggtaga
    41281 ttcggttctg aaaactggta caaagtgatg atggagatct ttaactataa tacagcacct
    41341 ggtgctacga tttatacgat tctgatcgtt gccttcactt tcttctacgc ctttgttcaa
    41401 gtaaaccctg agaaattagc ggaaaacttg caaaagcaag gaagttatat accaagcgta
    41461 cgccctggta aggggactga agagtatgtc tcaagattac tgatgcgttt aagtacagtt
    41521 ggtgcagtct tccttggttt agtggcattg cttccaatca ttgctcaaat ggtttgggat
    41581 cttccacaat caatcggatt aggcggtaca agcttactga tcgttatcgg tgtagcttta
    41641 gaaactgcga aacagttaga aggcttaatg ctgaaacgta aatatgttgg attcattgag
    41701 taagaaagcg tgttgaggtt tcccctcaac acacgttctc acacatttat taggagggaa
    41761 aacaatgaac ctcattttaa tggggctgcc aggcgcaggt aaaggaacac aagctgaaaa
    41821 aatcattgat gcttatggta ttccgcacat ctcaacagga gatatgttcc gcgcagcgat
    41881 gcaaaacgaa acagctcttg gcctggaagc aaagtcttat atggataaag gtgcattagt
    41941 tcctgatgaa gtaacaaatg gaatcgtgaa agagcgacta gctgaaccag atacagagaa
    42001 aggcttctta ttagatggct ttccacgtac gctagatcaa gcaaaagctc tggacgcaat
    42061 gctaaaagat ttgaataaaa aaattgatgc tgtcatcgat atccatgttg gtgaagaaat
    42121 cttggtcgaa cgtctagccg gccgatttat ctgcagcaat tgtggagcaa cttaccataa
    42181 aattttcaac cctacaaaag ttgaagacac atgtgatcgt tgcggtgggc atgaattcta
    42241 tcaaagagaa gatgataaac ctgagacggt taaaaatcgt ctggctatca acatcaaaaa
    42301 tagtgaacca atcttggctt attataaaga acaaggtttg ctaaacacta ttgatggtgc
    42361 tcgtgaaatc gatgctgtat ttgcagatgt acaaaaaatc attgaaaaat agcacgattg
    42421 cccgtagccg acttgcatta tgcagttact cttgtcaagt tcaataaatt atgatagaat
    42481 atgtcagtcc gacttctaga gaatcctcta gatgatccat tttgagaatt ttgaggtggg
    42541 aactgcagtt tccgccattt tatcgtgtga aaatgcgaaa caagtacaag gaggtactgt
    42601 gcgtggcaaa agaagatatg attgaagtcg aaggtacagt cgtcgaaact ttgccgaatg
    42661 caatgtttaa agttgaacta gaaaacggac accaagttct tgctactgtt tcaggtaaaa
    42721 ttcgtatgca ttacatccgt atcttacctg gtgacaaagt aacggttgaa ttgtctccat
    42781 acgatcttaa ccgtggccgt attacttatc gctttaaata attgtactcc gtaaaactac
    42841 aggaggtatt atcatgaaag taagaccatc agtaaaacca atgtgcgaac attgtaaagt
    42901 aattcgtcgt aaaggacgcg ttatggtgat ttgcccagca aatccaaaac ataaacaacg
    42961 tcaaggataa ttggaggtgc tataaatatg gctcgtattg caggagtaga tattcctcgt
    43021 gataaacgtg tagtagtttc acttacttat atctatggta ttggtaacac tactgctaaa
    43081 aagatcttag ctgatgctgg tgtatctgaa gatgttcgcg ttcgtgaatt aacgaatgaa
    43141 caaacagatg ctatccgtgc agaagtagat aaattaaaag ttgaagggga tcttcgtcgt
    43201 gaagtgaact tgaacatcaa acgtttgatg gaaatcggtt cttaccgtgg aatccgtcat
    43261 cgccgtggat tgcctgttcg tggacaaaac acgaaaaaca atgcacgtac tcgtaaaggc
    43321 ccagctcgcg ctatcgctgg caagaaaaaa taattcttaa gtgaaggagg ttaaaacttc
    43381 atggcagcaa aaaaagtgaa tcgtaaacgc cgtgtgaaga agaatataga agcaggtatt
    43441 gcacatatcc attctacatt caataacact atcatcatga tcactgatac tcacggaaat
    43501 gcattagcgt ggtcatcagc tggttcatta ggtttcaaag gaagcaaaaa atcaactcct
    43561 tttgccgctc aaatggcagc agaaactgct acaaaagcag caatggaaca cggattaaag
    43621 actgttgaag taacagttaa aggacctggt tctggacgtg aagcagcaat tcgttcatta
    43681 caagctacag gtttagaagt gactgcaatt cgtgacgtga ctccagttcc tcataatggt
    43741 gcccgccctc caaaacgccg tcgtgtttaa tgagtgccgc tcattttgag ttttatcagt
    43801 aacgtcattg aacaagacac ttttcgtttt gaaaggggta aagataagaa tgattgagtt
    43861 cgaaaaacca agaatcgcaa aaattgatga agaaaaagat tatggcaagt tcatcgttga
    43921 acctcttgaa agagggtatg ggactacttt agggaattcc ctacgtcgta ttttattatc
    43981 ttctttgcca ggtgctgcca tcactaatat tcaaatcgat ggtgtactgc atgaattctc
    44041 taccatcaaa ggtgttagag aagacgtcac tcaaatcatc ttgaacatta aaggcttagc
    44101 gctgaaaatg tatggccaag aagaaaaaac ccttgaaatc gatattaccg gacctgctac
    44161 agtaactgct ggcgatatta tcgttgatag tgatgtagaa attcttaaca aagatatgta
    44221 catctgtagt gtctctgaag gagctacgtt ccatgctcgc ttaacagtga aacctggacg
    44281 tggttatgtt caagcagatg aaaataaaaa agaagatatg ccaattggcg ttcttccagt
    44341 cgattcaatc tacacacctg ttcgtcgtgt gaactatcaa gttgagaaca cacgtgttgg
    44401 acaccgtgaa gattttgata aattgacgat ggagatttgg acagatggtt caattgaacc
    44461 gttggaagca atgagtttgt ctgcgaaaat catgactgaa catttggata tttttgtgaa
    44521 cttaactgat gaagcaaaaa atgctgaaat catggtcgaa aaagaagaaa cacaaaaaga
    44581 aaaaatgttg gaaatgacga tcgaagagtt agacttgtct gttcgctctt acaattgttt
    44641 gaaacgtgca ggaatcaata ctgtacaaga acttacaaat aaatctgagc ctgaaatgat
    44701 caaagtccgt aacttaggac gtaaatcatt agaagaagtt aaagcaaaat tgcacgactt
    44761 aggtttaggt ttacgtaaag aagattaaaa ccttttacga aggagggaaa ccaacgtgag
    44821 ttatcgtaaa ctaggacgca catctagcca acgtaaagcg atgttgcgtg atttaacaac
    44881 tgatttatta atcaacgaac gtattgtgac tactgaagct cgtgcgaaag aagttcgctc
    44941 aactgcagaa aaaatgatca ctttaggtaa acgcggagat ttgcatgcac gtcgtcaagc
    45001 tgcggctttc gtacgtaatg aagttgccag cgtgcgtgaa gaaaatgagg acatcgtcat
    45061 tgaatcagct ttacaaaaac tgttcaacga tattgcacct cgttacgcag aacgtcaagg
    45121 cggatacaca cgcattttga agacagaacc aagacgcggt gatggtgcac caatggttgt
    45181 cttagaactt gtctaaaatc acactaataa catcacttta tagatgattc ttttagagtg
    45241 ttatgatgtt ggaagatatt tttccgagtc tagctcagcg ctgctcctca agcgaatatc
    45301 gcttggggag taagcactca tcataaagtg tttttttata ccttcaatta cctgtcatga
    45361 cagatatgtt tgaaggcata aaaaaacatt ttaagcgaga aataattgaa aattttgtct
    45421 ttttttgata gtgttagtag gaactttagg atgaagaagg agtaatcatg gagccaatta
    45481 ttgaattaga aaagataaat tataaatacc agccagatga tcttcgcccc gcattgaaag
    45541 atgtctcctt tacaattgat aaaggtgagt ggatcgctat tattggacac aatggttcag
    45601 gaaaatcgac acttgccaaa acgatcaatg gattgcttct gccagaatca gggatcgtga
    45661 aagtgggaaa tcaaatattg gatgaagaaa atatttggac gatccgacag atggttggaa
    45721 tggtttttca aaatccagac aatcagtttg ttggttcgac agtagaagat gacgttgctt
    45781 ttggtcttga aaatcaaggg attcccagag aagaaatgct agtgcgtgtg aaagatgcac
    45841 ttgagaaagt tagaatggct gagtttgctt cacgcgagcc tgctcgttta tcaggagggc
    45901 aaaaacaacg tgttgccatt gccggcgtgg ttgccttacg acctgatatc attattttag
    45961 atgaagcaac cagtatgcta gatccagaag gtcgtgaaga agtgatctct acgatcaaga
    46021 agatcaaaga agaaagtcaa ttgaccgtta tatctatcac tcatgatatt gatgaagcag
    46081 ctaatgccaa tcggatacta gtgatgagac aaggcgaact tgtccgtgaa ggtacaccaa
    46141 aagaaatttt ttctgctggt cctgaactga tcgacttagg tctagatcta ccatttcctg
    46201 aaaaactgaa gagcgcactg aaagaacgtg gggttgatgt gcccagtgaa tatatgacag
    46261 aagaaaggat ggtggattgg ttatggacat ccgttttgaa caagtagact tcacttatca
    46321 gccgaataca ccatttgaac aaagagcctt atttgacatc aatatgacga tcaaagaaaa
    46381 cagttatact gcattagtag ggcataccgg aagcgggaaa tcaaccttac ttcagcattt
    46441 gaatgcgctt gttaagccaa caagcggtac agtccatatt ggagaacgag atattcagcc
    46501 ggatacggat aataagaatt taaagcccat ccgaaaaaaa gttggcatcg tctttcagtt
    46561 tccagaagca cagctattcg aagaaacggt agcaaaagac attgctttcg gtcctaaaaa
    46621 ctttggtgtc agcgaagaag aagcactagt cctagcaaaa gaaacattag aacaagttgg
    46681 gctggatgaa agctatttgg aacgttcgcc atttgaactt tcaggagggc aaatgcgtag
    46741 agtagcaatc gctggtgtgc ttgccatgag gccggaagta cttgtattgg atgaaccaac
    46801 ggcaggactt gatccccagg gcagaaaaga aatgatggag atgttttggc gtcttcataa
    46861 ggaacagcag atcactattg tattagttac gcatttaatg gatgatgtag ccaattttgc
    46921 agattatgtc tatgtgttgg aaaagggacg aatcgttaat agcggggagc cgcaagaggt
    46981 ctttcaaaac attgaatggc taaaagaaaa acaactaggc gtacctactg ccaccgagtt
    47041 tgcagaagaa ttaatggcta aagggatgaa ctttgctacc ttgcctttga cagctgaaga
    47101 attagcagac gctatcgtcc attatgctgg aggaaatgcc catgatgaat aaattgatat
    47161 ttggtcgtta tatgcctgga gattccttga tccatcgatt ggatccccga gctaaattat
    47221 tagccagttt ttattttatc ggaatcattt ttttagcaaa taattgggaa acgtaccttt
    47281 tgttggcatt tttcacatta ctttctgtct tcttgtcaaa agtagatttg aaatttttta
    47341 tccgaggcat tcgcccattg atctggctaa tcctcttcac tgtagctttg caggtcttgt
    47401 ttacaagtgg cggagaaact tattggagtt ggggtgtttt ccatatcact gaatttggtg
    47461 tgatgaacgg cctctttatt ttctgtcgat tcgtgttgat catttttatg tcgactctac
    47521 tcacgcttac tacaccgcct ttggaattat cggatgcgat tgagtacttg cttcgtccat
    47581 tgaaagccgt acggttccca gtccacgaaa tttcattgat gctgtcgatt gctcttcgtt
    47641 ttgtgcctac attgatggac gaaacagaaa agatcatgaa cgctcagcgc gctcgcggtg
    47701 ttgattttgg tgaaggaaac ctagttcaga aaatgaaagc agtcattcct ttgctgattc
    47761 ctttatttgt cagcagcttc aaccgtgcgg aagatcttgc gactgctatg gaagcaagag
    47821 gctacaaagg tggggaagga agaacgaaat atcgtgtatt gcattggcat aatagagaca
    47881 cgatggttat cattgctttt gtattattaa ctgtgctact gatcttttta agaggataaa
    47941 cgttcagtgg gccgctatct attcttttct tgctgatctg tttgcaagaa aggatgcaag
    48001 cagtgtatga caagaaatat tagggtctgt ggcagactaa ggtcacaggc ctctttcttt
    48061 tatctgaaaa gaaagaacga aaaaatttta tagaaaaatc attattccag ataacctttt
    48121 aggaacaaag gagagaaaaa catggtacgt tacaaagcaa tcattgcgta cgacggaaca
    48181 aattttaatg gattccaaaa acagccaaat gggcgtactg ttcaagaaga agtagaaaaa
    48241 acattacaaa aaatggcaaa tggaaaagaa atcacggtct ttggttcggg aaggacagat
    48301 gccggagtac atgcgatcgg gcaagtaatc cattttgatt atccagagga gcgtccgtta
    48361 gaacgaatgc gtttcgcgct agatacccag tcaccagagg atattgctgt aagacaagta
    48421 gaaattgttt cagaagactt ccacgcaaga tatttggtca aagaaaagac gtatcaattt
    48481 cgagtggata tagggaaacc acgcagtcct tttcgacgcc attatgcaag ttattttcct
    48541 tacccacttg atttggaaaa aattcagcgg gcgcttcctg atttattagg gactcacgat
    48601 ttcacctctt tttgtgcatc aggaagctcg atagaggata aaatacgtac gatctacgag
    48661 gctaagatgg aggtaaatga aacaaaagac gaattgttgt ttacatttag gggaaatggc
    48721 ttcttgtata agatgatacg gatcttagta ggaacgcttt tgaaaattgg caatggccga
    48781 ttgcctgaag atagtatccc agatattatt gcgaaaaaag atcgtaatgc agcaggacct
    48841 acagcacacc ctgaaggact ttatttgtat gaagtgaaat atgaataaga ggttatgata
    48901 gaagtggtca gcttcaagaa ataagaaggt atttacgaaa attacttctc aaaattttgc
    48961 aaaatttcgg cttattttcg aagaagctac ttctggaaca ccgtttaagg aagaggtcgt
    49021 gaaatcagcg ttttgacctg agtattagag aaacaaacgg gaaaatagct cctcatattt
    49081 tgccgtttgt tgagctaata ccgaaggtca gctgattgaa caccgtttaa gaaagaggtc
    49141 gtgagcctgt catttaactc tgagtcacaa agagcaattt caaaaaacag cttctcatct
    49201 ttgatgaata tcgtgacttg tggacgaggc gttgataagt gaatcatctt tttgttacct
    49261 attttttctg taaccaaaaa acgatggaac gttgttttga ttgcccttgg tgcggacagt
    49321 ctgaacaggt tccatcgttt ctttattttc tacgtcttct tctgtgtgtg tttcgtggtt
    49381 gttcttctat tgctggatca atcgtgccat aaaaggggcg attgcggtca aggtaccaga
    49441 cataaagaat aaacaatgca atacatagga caaaaaggat tgcacctatc gtaaatcctt
    49501 caggcaagta actgaaagtg acagtatgtt tacctgctgg aacttttatc atcaagaatg
    49561 cgtctttgaa attgctgacc ttgactggtt tcccatcaat tttagctttc catcctttgt
    49621 cataaggaat agttgtcacc aacatggaat cttcagcggt atttacagtc ccagaagctt
    49681 ttctgccagt ggcttccatt tcgacacctt tttctttgat ctgattcatt gcggcttgat
    49741 aggctacaac atctagacca acgactttag gctccatgaa acttatttct ttcgtcccat
    49801 aaaaacttgc agtaaatgtc actgttgtct cttgaggata atagccaaga tcatagtatt
    49861 gaccagaaat gttgatttgc gtttttcgcg atgtaccatt gacagtgatc gtcgcactag
    49921 aactttctaa ttgcgcaaaa ttggttggga acaaacttaa gtaagcttgt gtatttgcag
    49981 gcacatggac ttcccaagtg agctcttttg gctggttatc tgctgtttct gagtaagtga
    50041 cgccagtcgt tgtctttgtg atcgtcgtat tcaactgatt cttcaaagta ggtgtataga
    50101 atgtaaaata ctgttcattt agaccagaca atgtattgat caagtttgtc tgactggtca
    50161 aattatctgt cactggctgc tcaacatcat taacggacaa cggtgcagta aatgctagtg
    50221 gcaatgcatt gacattctga tacagtgtat agtcgccgct ttgaccagct tggcggaagc
    50281 catatttact gaacgtgctt tcgtttttag aaatgttata tttgattcct gtaaacccat
    50341 ccatcagcaa agtattattg ttataacgga tattcaaatt tgtccctctt gaacggaaac
    50401 ctaatttatc caggtaagag gaagaattac gatttcttat agaagaaaac aaactgatac
    50461 cactgtaacc atagttgatc gaatcgtttg cagatactgg atccagattt tccaagcggt
    50521 aaaacgagtc ggaatctttt tttgtttcat ttacaagagc tttcaagtca ggataaggat
    50581 cagtatataa actgcgggaa gcataattcc aatcatcaag aatgccatgg atcatactgt
    50641 tcgtattgac cagtgcttca gcagacatga tcaataataa caatatactc agatgattga
    50701 atgaaagttt tttatgctga taaaatccca cagcaaaagc ataaatccct aagaaaacca
    50761 ctgtcaatac aaaggaagtc atcgtcacat aggtgtagct tccttcaggt ttgatgcccc
    50821 atgccaccgc aaagagagca gctacgacca aaatgattcc taacaacagc ccacgatcgt
    50881 cttgttctat cttttcccat ccttttcctg caagcaggag cactaagaaa gagaacagat
    50941 aggcataacg gaataaaaac atattcggtg catgcatacc atgccagaac aaattcaatg
    51001 gaacaagata aaaacttgcg ataagtatgg cgaaaagact gccgtacaaa aatttatttt
    51061 tcaacggtac tttccgactg gcaaaataaa acagacagag gactaatggt agcagacctg
    51121 cgtaaacgaa cggaatcgat ccgtattttg tcgtgtcata aacaccaatc atatttttca
    51181 tgattagatc cagataagaa gtcgcttctg ttttcaacgt agtgatctga ctcagtgcct
    51241 cgccatttga ccgaagatcc agcactgctg gcaatacaat gatcattgaa gcgccgcctg
    51301 ccagtaaaga agtgatacca taaggaacaa tcgttttttt atattctgac cagtttgtca
    51361 atagacgggc gataaaatat aagaaagaaa atacgccaat cataaaaccc atataaaaac
    51421 tggataaaaa caagagtaaa taactgataa ataaaagttt cggccgttta agatccataa
    51481 cacgatgaat ccccaaaatc actaatggaa gataaaaaaa tgcatccagc cacatgatga
    51541 tctccgaatg tgcagtgata aatgagatca atgcgtaact gacgctaagt gcaacatgcc
    51601 cccagcgagg aatcttgaac gtacgtgcaa gaaaccaaaa agccaatccg gcacagccga
    51661 ccttaagcaa agtcagaaca tacagtgcat ctggcatcat ctggtttgga aaaaagaaca
    51721 ccagtggcgt gaagatcccg cctagatagt aagaaattaa agataaataa ttcaatccta
    51781 gagaagcatt ccatgtataa aaaatacttt gctttccaag aagaacattt cggaagctgg
    51841 catgaaaatt agaaaactgt gaaaaggcat cacttgccaa aatacttctg ctgcttccag
    51901 gatagattcc gatacttaga taaacaagtg ctaaaatcaa aaacggaatc aggaaactag
    51961 ctgctgcgta gcgtccgttt tctctaaaga atgactttaa attttttttc atatttattt
    52021 tccaccaaat ttctatgaag ttgtattcag tttatcatat ccttgttttt ctctgcttaa
    52081 aaagagtcta gttttcacaa aaaaataaaa tttagaataa ataacttcat aatttgttcg
    52141 tataacaaaa ataaacgcaa aaaaagggta ggaatcaaaa gtcccaccct taaaaatttt
    52201 tattaaataa aaaaccgttc actatctgaa cggtccaagt atcattcaat taaacgcgtt
    52261 caacttttcc tgatttcaaa gcacgagttg acacccaaac ttttttaggt tttccgtcga
    52321 ccataacgcg aactttttgt aagttaggtt taacagtacg ttttgttgag ttcatagcgt
    52381 gtgaacggtt gtttccactt tttgtcttgc gacctgtaaa gtaacaaact tttgccatgg
    52441 taatttcctc ctttgccttg atttggagca atagaataat tcagctcata ccagactaac
    52501 atatcatata gaatgggaat ttgcaagtac attttcatag atacaattga caattgagaa
    52561 gaataattgt aaattaaaca aggttatacc tgaaattttg caaggttttt gagtactttg
    52621 ggtaactgcc ttttatttca agttgcgcta tgataaaata tgatagaaga aaaatgggag
    52681 ttttttaccc gttaaggagg ctcattcatg gctgtaaaaa ttcaaacgtc agctggaacc
    52741 attgaaatta ccaatgatgt aattgcaaca gttgttggtg gcgccgcgac agatgtgttc
    52801 ggtgttgtag gaatggccag caaaaatcaa attaaagata atattactga gattttgcgt
    52861 aaagaaaatt actcaagagg agtagttgtc cgccaagaag ataatggtat tgctgtagat
    52921 gtttatacga ttatcagcta tggtacgaaa atctctgaag tttcccgcaa cgtccaagaa
    52981 aaagtgaaat acaatctaga ggcattatta ggcgtaactg ccaattcagt taatgtcttt
    53041 gtacaaggtg ttcgtgtact gccagactag gcaggagact ggctggtaac tcagcagtcg
    53101 atctgaagga ggattatcta ggtgagtgta acagaaataa gtgcaagcca gttccaggaa
    53161 atggtccagg caggtgcgaa tcgtctgcaa gtaaatgcag aatacgtcaa ttcattaaat
    53221 gtattccctg tgccagatgg cgatacggga acaaatatga atctatctat gactagtgga
    53281 gctaaggcag tagtagattc aacctcagaa aaagtaggag aattagcagc aatgctttca
    53341 aaaggattgc tgatgggtgc gcgcggaaat tccggcgtta ttttgtctca attgtttcgt
    53401 ggattttcta agcaaattcc agatgttgtc tcattaaatg cttctgatct tgctgcagcc
    53461 ttcactcatg gagttgaaac tgcgtataaa gcagtaatga aaccagtaga aggaacgatt
    53521 ttgacagtag ctagagaagc agcgaaagct ggagaaaaga aagcaaaaag tactgatgat
    53581 gtcgttgaag taatgacagc tgttgtaaaa ggagcaaagc gtgctttagc taaaactcca
    53641 gacttgcttc cagtcctaaa agaagtcggt gtcgtagaca gtggagggca aggactgctg
    53701 tttgtttatg agggcttttt aagtgcattg aatggagaat tccaagcgga tgaaacatat
    53761 gaaccttctc cagcagaaat ggatgatatg gtcaatgcag aacatcatcg cagtgtccaa
    53821 ggtcaaatgg cgacagaaga tatccatttt ggttactgta cagaaatcat ggtaaaaatc
    53881 ggagaaggac ctacagtcga tagtacattc gattacgaag aattccgtaa ctatttagat
    53941 ggtataggag attctttact tgtggtcaat gatgacgaga tcatcaaagt ccacgtgcat
    54001 acagaaaacc caggagaagt cttgaattat ggacaaaaat tcggttcatt agtcaaaatc
    54061 aaagtcgaca acatgcgctt gcagcatgag acgattttgg aacacgatga agaagtgaac
    54121 gagtttgcga aaaaagaaat accacgtatc ccgtatggta tcgtagcgat cgctgctggt
    54181 aaaggcgtcc aagagctgtt tgaaagttta ggcgctaatt atgttatcag tggtggacaa
    54241 acaatgaatc caagtacgga agacattgtt aaagcgattc aagaagtaaa cgcagataaa
    54301 gtgattgtct tgccaaacaa taagaacatc ttcatggcag ctgatcaagc agcagaagta
    54361 gcagatatcc cagtagcagt tgttccttca agaacgattt cccaaggatt gacagctatg
    54421 ctttcattca atgatcaagc ttctttagaa gaaaacaaag aaacgatgac agaaatgttg
    54481 tctagcgttg tgagcggtca agtcactcac gcgatcagag atacctcaat tgacggtgta
    54541 gagatcaaag aaggagactt tttgggcatg atcgatggaa aaatcctgat ctctaaccca
    54601 gatatcacag caacagcgtt aagtacacta gaacaaatga tcaatgagga cacagagatc
    54661 gtaacgatct tggcaggtga tgaaggaaca gttgaacaag caaatgaatt tgctgagaaa
    54721 ctaacagaaa aacatcctga tttggaaatc gagatccacc aaggagatca gcctgtctat
    54781 ccttatctat tttctgctga ataatttctg tgtcagaata tctttctaac acagtattca
    54841 ttcataaaag gccttcggtt agtgatcagg tatgatcgct gaccaagtcc tttttttgtt
    54901 aaaggaggga ggaaaaattt atgcgttctt tagatgatcc aatcactatg ctggcaggag
    54961 tcggagaaaa aagagcagct agtcttgcca gcttgggcat ccaaacgatt gaagacttac
    55021 tgacttatta tccttttcgc tacgaagata ttcaggaaag aaatctaaac gagatccagg
    55081 atcaagaaaa ggttactttg aaaggaatcg tagtctcgcc tcctgtgatg aatcgatttg
    55141 gttataaaaa aagccgattg caatttcgta tgatgcaaga acatgatgtg ttcaacgttt
    55201 ctttttttaa tcaaccttat ctaaaagaaa aagtcatttt atcggaggaa atcgccgtat
    55261 acggtaaatg ggatgcaaag cgtaaagcct tgaacgggat gaagatttta ggttctcaaa
    55321 caatggatga cttttcgccg atatatcacg tcaacaaatc aattcgtcaa acgacattag
    55381 ttgatctaat caaaaaaggg tttcaagaat acggcacatt gattgaagaa aatctgccaa
    55441 acaaccttgt ggagaaatat cgactgcttg accgagcttc tgctgtaaga agtatgcatt
    55501 ttccaaaaga ccacgaagaa aaccatcaag ccaaacgacg tgtcgttttt gaagagttct
    55561 ttttatttca aatgcgtctt caaggattga aaaaagcaga aaaagcagaa acgaatggtt
    55621 tggagatcct ttatgatgtc caaaaattga aacaatttac tcaaaagcta ccttttgaac
    55681 tgacaaatgc acaaaaacgt gtaacgaatg aaatctgtcg ggatcttcgc agtccgcagc
    55741 atatgcagcg acttttgcag ggagatgtag gtagcggaaa aacagtggtt gccgcgattg
    55801 cgttatacgc taccgttaca gcaggtttcc aaggtgcgtt gatggtgcct acagaaatct
    55861 tggcacaaca acatatggaa agcttgcaac agctgtttga tcccaatgaa gtaaccatcg
    55921 cattgattac ggggtcaacg aaagcaaaag aacgacgtga gctccttgaa aaactagagc
    55981 aaggggaaat taacgtcgtg atcggcacac atgcattgat ccaagatgga gtcgaatttc
    56041 agaatttagg tctagttatt acggatgagc agcaccgttt tggcgtgaac cagcggaaag
    56101 tacttcgtga aaaaggctgg cgaccagatg tcttatttat gacagcgact ccgattccta
    56161 gaacattagc tattacagca tatggtgaga tggatgtatc tatcattgat gaacttccag
    56221 ctggacgtat cccgatcgaa acacgctggg taagaacacc tcaattggac agtgtactgg
    56281 attggacgaa aaaagaactg gcaagaggac atcaaatgta tgtcatctgt ccgctgattg
    56341 aagaatcaga agcattagat gtaaaaaatg cagtggaaat ctatgaaaaa cttcgtgaac
    56401 tatttgcacc aaaatatgaa gttggcttgt tacatggtaa aatgaagaat caggaaaaag
    56461 aagtaatcat ggaagccttc aaagacaacc agatgcagat attagtttcg actactgtaa
    56521 ttgaagtagg ggtaaacgtg ccgaacgcga ccgtcatgct gatcatggat gcggatcgat
    56581 ttggattggc acagctgcac caacttcgtg gacgtgttgg acgcggaagt gatgcttcct
    56641 actgtatctt agttgctaat cctaaaaatg aactaggtgt ggaacggatg aaaatcatga
    56701 cagagaccac caatggtttt gtactaagcg aaaaagatct ggaattacgt ggtcctggtg
    56761 aagtatttgg cttccgtcaa tctggtctgc ctcaatttgc gattgctgac ttggtgacgg
    56821 atggaaatgt tttggaggta gccagagaag aggctgcagc cctttggcaa ataaaggatt
    56881 ggcagatgct tcctgagtat cagcctttag cgcaaagcct ccaaatagaa aatcaggata
    56941 atcgttattt cgattagcag actgtgctat actttatact gatgacggaa aaaggagtgg
    57001 aaacaatgaa aattgccgta gatgcaatgg gcggagatca cgcacctcaa gcaattgtag
    57061 aaggcgtggc tttagcgcag caagattttc cagaagtaga attcttactt tacggaaaag
    57121 aagcagaaat caagaaatac ttaacaaatg aaaaaaacat cacgattatc catacagacg
    57181 aaaaaatcaa tagtgatgat gagccagtaa aagcaattcg acgaaaaaag actgcatcaa
    57241 tggtccttgc tgcacaagca gtgaaaaacg gtgaagcaga tgctgtattt tcagcaggga
    57301 atacaggcgc gctactagca gcagggttgt tcatcgtagg acgtatcaaa aatatcgaac
    57361 gccctggctt gatgtctacc ttgccagtag tagggaaaga aggtgccggt ttcgatatgc
    57421 tggatcttgg cgctaacgca gaaaacaaac cagaacattt gttgcaatac ggtattttag
    57481 gttcttttta tgcacgtaaa gtccgaggta tcggacgtcc tcgtgtcgca ctcttaaaca
    57541 acggaacaga agcaacaaaa ggtagtgaag tgacgaaaaa agcctatgaa ctccttcaga
    57601 atgaaacaag cttgaatttt attggaaacg tagaagctcg tgagctactc aatggtgtgg
    57661 ctgatgtagt ggtcacagat ggatttacag gcaacgctgt tttgaaatct attgaaggaa
    57721 cagcaatgaa tatgatgaat ctattaaaat ctgctattct aaatgaaggg atcaaaggaa
    57781 aaatgggcgc tatgctttta aaagacggct tacgttcttt gaaagcagaa atggattatt
    57841 ccaaacatgg cggtgccgtt ttgtttggct tgaaagcacc agtcattaaa actcatggag
    57901 caacaggccc cgatgctgtt cgctatacga tccgccaaat ccacacaatg cttgagacag
    57961 atgtagttgg acaattagtc gaacaatttg aaaaaagcga agaatagtat ttggatatct
    58021 gaagcgatcc gttccattga aaaaaaggtg gacattcctg aaaaatgcca gtaaaattag
    58081 ccatggtgta ggtaattgac aagtgtatga ttcttggagg tgaaaaagtt gactcgcgaa
    58141 gaagtattta acaaagtagc gaaaattatt tcaaatcatt ttgagataga taccgataaa
    58201 gtgacggatg aattgaacat caaagatgat ttaaaagctg attcaattag tattatggaa
    58261 ttcgttttag agcttgaaga tgaattcggt acggaaattt cagatgaaga cgctgaacaa
    58321 attgaaacag tcggtggcgc agtagattat atcagcagcc atcttaaata atttcaaata
    58381 aaagcaaaga aggataaaaa gctgcatgca gctttttatc cttctttttt taatcttttt
    58441 gacacgtaaa agtcattttt ctgataattc tggcgataaa cagaaattat gttgcaaagt
    58501 aaagcggttt tctatataat tattaataat tcattacaca aagataagaa taacctttgt
    58561 tataaaacga tttattctgt gtaatgtcct tttttattaa gaaaaacttc catttaggaa
    58621 gcagagaggg gtattcgatt gtccgataac caattattag aagttcagaa cctacataca
    58681 ggattccgac tcaaagatga ctattacgat gcagtagatg acgtttcatt tactttagac
    58741 aaaaacgaga ttttagcaat cgttggggaa tctgggtgcg ggaaaagtac cttggctact
    58801 acgattatgg gattacttga tcctaataac acaaaaatta caggtgagat tttatataac
    58861 gatctgaatt taatcgacct gaacgaaacg ctctataata aaatccgcgg aaatgatatc
    58921 ggaatgattt tccaagatcc gttgtctgca ttaaatcctc tcatgagaat cgaagaccag
    58981 atcaaagaag gactttccta tcacacaaag atgaatgcag aacagcgtca agctcgtgca
    59041 ctagaattgc tagaacaagt agggattcct aatcctgcga gagttggacg ccaatatccc
    59101 catgaactat caggcggtat gagacaacgt gtcatcatcg caatcgcaat cgcctgcaaa
    59161 cctccaatcg tcattgcaga tgaaccgacg acagccctag atgtaaccat ccaagcacag
    59221 attcttgatt tactgaaaga ccttcaggaa gaaacaaaaa cagggatcat cttgatcact
    59281 catgacttag gagtcgtagc agaaatggct gatcgagtgg cagtgatgta tggcggacag
    59341 ttcgttgaag tagcaggtgt aaaagaactg tttgatcatc ctaagcatcc ttatacacgc
    59401 tctttactga actctatacc acaagaagga aatcatgatg cagaactcca tgtgatcgaa
    59461 ggtgtcgttc cttctctgaa aaacatgcct cgtaaaggtt gtcggtttgc accacgtatt
    59521 ccatggatac cagcaagcga tcatgaagaa gagcctatcc ttcatgaagt cgcaccgaac
    59581 cacttggtac gttgctcctg ctataagcat ttccacttta gagacgaaaa aggagaggtg
    59641 tagatgacag aattaatcac aatcaaagac ctgaaagttc attaccctat tcgcagtgga
    59701 ttcttcaatc gagtaacgga tcatgtatat gctgtagatg gtgtggattt tattatcgaa
    59761 aaaggaaaga catatggttt agtgggagag tctggctctg gaaaatctac tacgggaaaa
    59821 gccgttgtgg gattagaaaa ggtaacagcc ggacaaatca tgtatgaagg aaaagatgta
    59881 acgaagcgaa gcaaccgcaa aaaaatgggt tataacaagg atgtgcagat gatcttccaa
    59941 gattcaatgt ccagtttgaa tcctaaaaag cgagtgttgg atatcattgc tgaacccatc
    60001 cgaaattttg aacggttaag cgatcaagaa gaaaagaaaa aggtaaaagg actgctagat
    60061 atcgttggga tgccggaaga tgcgctatat aaatatcctc atgaattttc aggcggacaa
    60121 cgtcaacgtc taggagtagc ccgtgctgtt gctaccaatc caaaactgat cgtagccgat
    60181 gaacctgtat ctgctctgga tctatctgtt caagcgcaag tattgaattt catgaaacga
    60241 atccagcaag aatacggcct cagctattta ttcatttcac atgatttagg tgtagtaaaa
    60301 cacatgtgcg acaatatcgc aattatgtac aaaggtcgat ttgtagaaat cggtacaaga
    60361 gaagacattt ataatgaccc gcgacatatc tatacgaaac gtctgctttc agctattccg
    60421 caaatcgatg tagaaaatag ggaaagccac aaagaaaatc gacgaagagt agaacaagag
    60481 tatatccaaa accaaaaaga atactatgat gcgactggtc gagtctacga tttgcgtacg
    60541 atcacaacta cacacaaagt ggcgttgaaa gatggaggtg caagctaatg tggaaaacga
    60601 ttctgcgacg tgttttattg atgatcccgc aagttattat tttaagtgtt ctgatcttct
    60661 tattagccca agcgatgccg ggggatccat ttaccggttt gatcaatcca aatcaggatc
    60721 cggcagtgat cgaacagatg cgacaagcag ctggcttgaa tgacccatgg tatgtccagt
    60781 acttccgttg gatcggaaat gctttgcaag gcgattttgg tcaaagtttc ttatacaaac
    60841 gctctgttgc tgacttgatc ggcgaacgga tcatcaacac tttatatcta tcgatcttga
    60901 cagttgtcct tacttatttg attgctgtgc ctctggggat gcttgctggc cggtatcaaa
    60961 attcaatctt ggataagatt gtcgtaatct acaacttctt tagttttgct gttcctttat
    61021 ttatcttcgg cttgatcatg ctatttgttt ttggttatcg tttaggctgg ttcccaacaa
    61081 gtggatcaca aacactaggt ttgcaaggtg gatttatcac tcaatggata gaccgtttga
    61141 aatatattct gttaccatca attacccaag catttttggc gactgccgtc acaatccaat
    61201 atctgcgaag tgaagtaatc gattcgaaat cgctcgattt tgtcagaaca gcccgttcca
    61261 aaggggtacc gacgaataaa gtattcagtc gacatatttt ccgaaatgca gcgttgccga
    61321 tggcttctca aatggggtat gaaatcactt cgttgattgc tggttctgta gttatcgaaa
    61381 agatttttgg ttatccggga gtcggaaaac tatttattga ttccatcggc caacgggact
    61441 ataccgtgat cacatcctta gtattgattt taggaatcgc gacgctagtg gggacattac
    61501 tttcagatat catcatgagt atcgttgacc cgcgtattcg gattcaataa aaccaatcag
    61561 aaaggagaat ggatcgatga gtgaaaaaaa caatacagca gttcaagaaa gtattcctcc
    61621 tatggggata cgaatgattg ctcgagaatt taaaaaagat aaaattgcta ttttttcatt
    61681 aggtttgcta gtggttttat tattagtgat ctttatcggt gcgatgctga ccgatcaaga
    61741 caaagtgatg tatgttagta tcttcgacaa atacgctgca ccaggaacag tttcgacaca
    61801 aggacaaaag ttcattctgg gagcagatga aggcggacgt gatgtattag gacaattgat
    61861 cataggtgct agaaactctg ttacgatcgg atttgcgatc acgatcctta cttcgatcat
    61921 cggggttgga ttagggatca tctctggcta ctacggaggg atcattgaca acatcttgat
    61981 gcggatcgtt gattttatca tgattctacc gatcatgctg atcattatcg tcttcgtatc
    62041 gattatttcc agatacaatg tctggtcctt tatattcatc atgagtgcat tttattgggt
    62101 agctaaagcc cgattattcc gaagcaagac attatctgaa gcaagaagag attatgtcag
    62161 tgcctcaaaa acaatgggaa ccaatgattt taaaatcatg ttccgcgaaa tcatgccgaa
    62221 tctaagttca ttaatcatta ctaatttgac gatgaacttt gcggcaaaca tcggtatcga
    62281 gacaactttg actttcttag gtttcggctt gccggcaaat gtacctagtt taggtacatt
    62341 gatcggttat gcaagtaacg gagaagtctt agtgaatcgg caatggatct ggttacccgc
    62401 atcaatcctt attttagttt tgatgttgag tatcaattat gttggacaag cattcaagcg
    62461 ttctgcagat gcgcgccaac ggttaggcta gtatagaagc gaagggggaa ataggaatga
    62521 agaaaacgat ttttggattt gcagcgctga tgtctgctgt cgttcttgca gcatgcgggg
    62581 gcggaggtac agatacctct ggaaacaact ctggaggcaa cggcaataac aaagaggaat
    62641 taacttttcc aattgcaaca aaaaataatg atgatgcaat cgaagacggc gaattagaag
    62701 ctgcggtcgc aacggacagt cagtttaaag gattgttcca gtgggagttt taccaagatt
    62761 catatgatgc agcttttatg gctccttctc atgaaccgct atttgcaaac gatgacgatt
    62821 tcagaatcac agacgacgga gctgcaacgc ttgatctaga tgaagatacg aaaaaagcga
    62881 caatcaaagt aaaagacaac gtcaaatggt cagatggtga agatgtaacg gcggacgatg
    62941 tgattttccc ttacgaaatc attgggaata aagattacac tggtatccgt tatgacgaca
    63001 ctttccgtaa catcgtaggt atggaagaat atcatgatgg aagtgccgac acaatctccg
    63061 gaatcaaaaa aatagacgac aaaacagttg aaatcgaata taaagaagta aacccaagca
    63121 tgcttcaatc gggtggtggt atctggtcat atgcagcacc aaaacatacg ttagaaggtg
    63181 tagcaatcaa agatatggaa tcaagcgatc aagtacgtaa aaatccagtg acttttggcc
    63241 cttattacat gagtaatatc gttgcaggag aatcagtaga atacttgcca aacgagcact
    63301 actggaatgg tacgcctaaa ttgaaaaaga tcacgatgaa atctgtaccg atggcaagtg
    63361 caactgaagc attgaactct aaattatatg atatgatttt ccaaatgcca acagatactt
    63421 acgataccta taaagaaatt gctggctata caaacttagg ccgtgaacaa acttcttata
    63481 cttatctagg attcaagtta ggtaaatgga atgcagatac aaagagtgtg gaatacaatc
    63541 cagattcaaa aatggctgat aaatcattac gtcaagcaat gggctatgca ttagataata
    63601 atgcagtagg tgaacgtttc tatgcaggtt tgagaagcaa tgcgacttca ttgattcctc
    63661 cagtattcca gtcataccat gatgatgaga tgaaaggatt cacacaagat ctagacaaag
    63721 cgaaaaaact attagatgat gctggctaca aagatgtgga tgacgatggt ttaagagaag
    63781 acaaagatgg aaataaacta acaatcaact ttgcttcgat gtccggtggg gaaacagcgc
    63841 aaccattggc agattactat atccaacaat ggaaagaaat tggtttggat gtccaataca
    63901 caacaggtcg tctgatcgaa ttcaattctt tctatgataa attagaaaac gatgatcctg
    63961 aaattgatgt ttaccaagct gcttggaata caggaactga tccaaatcca agtggactat
    64021 ggggaccaaa tgctgcgttc aactacactc gttatgaatc agaagaaaat acaaaattga
    64081 tcaacgatat cagttcaagc aaagcatttg atgaagagta ccaaaaagaa gcatatcaaa
    64141 aatggcaaca atatgcattt gaagaagcat ttgcgattcc aacgttgttc cgtaatgaag
    64201 tattgccagt caacgaccgt gtcaaagact gggattggtc ttatgatgta ccaaacccat
    64261 gggcaaatgt ttctgttaca gcagattcac gttcataatc actaaaaatg accgaaaaag
    64321 ggcgatgtcc tttttcggtt ttttgatatt tttctgttta tttctctaat attcaggtca
    64381 aggcgctgat ttcatgactt ctccaataaa cggtgttcaa agtccagttt ctcggtatta
    64441 agtcaaattt atgcaaaaat atggaaagcc attttcacaa aattttttct tcatactcga
    64501 aactaaacga atttttcaca acttctcgtc aatcactagg attattaaag ctttacttac
    64561 cttttgaccg aaccatttca aatttgacaa aaaaccagta taataaggaa gtatcgaaaa
    64621 aatatccata aaaggaatgt ggaaaatgga caaccagctg acaaaagaac taaaagaaaa
    64681 ctataacatc gtttttcacg atctaaattt gcttgaacaa gcttttaccc attcatccta
    64741 tgtgaatgag catcgcaatc tgcaattatc ggataatgag cgacttgaat ttttaggaga
    64801 tgccgtttta gaactgatgg tttctcagta tttattccgt ttatatcctc atttgccaga
    64861 aggaaaattg acaaaaacac gagctgcgat cgttcgcgaa gacagcttgt cgaaatttgc
    64921 caaagaatgt cactttgatc aatatgtttt gttgggcaag ggagaagaga attcaggagg
    64981 acgtacgcga ccagcattgc tttgcgacct attcgaagct tttttaggcg cgttatatct
    65041 tgaccaggga ttcgacacga cccatgcatt catcgaaaaa gtgatttttc ctaaagtcaa
    65101 agcaggtgct ttttcacatg agatggatca taaaacaaaa ctacaagaag tcttgcaaaa
    65161 atcaggtgat gtatcaatcg aataccgatt gatcaatgaa gaaggtccag ctcatgaacg
    65221 agtattttgg atcgaagttt atgtagatga tcaattgatt ggcactggac aagggaaatc
    65281 gaaaaaatta gcagaacaag ctgcggcgga aaatgcattg gcagcactgt aaaagtaagt
    65341 gagggaaagc tttgtatttg aaacgaattg aaatagccgg ttttaaatca tttgcagaca
    65401 agacagtcat tgattttgaa aatagcgtca cagcagtggt tggaccaaat ggcagcggaa
    65461 aaagcaatat tacagaggct atccgctggg tattaggaga acaatctgct aaaagtctgc
    65521 gaggcggaaa aatgccggat atcatctttg ccggttccga tacccgtaag cagctgaata
    65581 ttgcagaagt cacagtgatt ttagacaata gtgatcatta tctgccattg gagtacaatg
    65641 agatcagtgt aacccgccgt tatcgacgga ctggggaaag cgagtttttc atcaataaac
    65701 aaagctgcag attaaaagat atccaagaat tgttcttaga ttctggatta ggaaaagaat
    65761 cgttctcaat catttctcaa ggaaaagtag aagcgatttt cagtagtaaa ccggaagacc
    65821 gtcgtgggat ctttgaagaa gcagctggtg tcttgaaata caagcagcgg aaaaagaaag
    65881 cagaacagaa gctttttgaa acagaagaca acctcagccg cgtccaagac atcatccacg
    65941 aattggaaga acagttaact cctttggccg cccagagtga ggcagcaaag gagtttttac
    66001 ggctaaaaga aacactgact caaaccgatg tctctttgat ggttgctgaa atcaagacag
    66061 caaaaaaaga ttgggacaac aaacaagcac agcttgcgaa attcaatcta gaattaggca
    66121 aactatctga gtcgatccaa gaacaagaat ccattttggc gaagcagcgt aaagaaaatg
    66181 cgcaagccga tcgtctgatc gaaaaaaatc agcaagtatt attagatctt tcggaaaaac
    66241 tgaagcagac agaaggacaa aaagatgttt tgcaggagcg gacaaagcat acacaaaaaa
    66301 gctcgcaaga atatcaaact tcattagcag aagcacaaaa aaaggttaaa cattttgaaa
    66361 agcttcaaga aagcttgatg aaagcagcag cagaaaaaga aacagagatc caaaaagctg
    66421 aagcaaatct cataaaaaca cagcaagaat tagaaaaata ccaaaaatca acgaaagaat
    66481 tattggcaga attaagagat caatatgttg atttgatgca agaacaagca gctgtaggaa
    66541 acgaactgaa gtatctagaa cgtcaatata tacaagaaac agcaaaaagc aagcagacgt
    66601 tagccaagca atcggaagta gaagcatcag tagaccgatt gatcttacaa aaagaagaat
    66661 tgacacaaaa gcaggcgcag ctaaaatcat ctttaactga aacaaaagag aagttagaaa
    66721 tgatccaaca aaacgggaaa aagttccaag aagcattagc aaaagaacag cctaaaatgt
    66781 atcaattaat gaatcaagtc cagcagctac gtgctcgtaa gaaaagcctt caagaaatcc
    66841 aagaaaacta ttttggtttt taccaagggg ttcgattggt cttgcagcat aaacagcagc
    66901 tttcgggtat tgtcggagca gtggctgaac tgatcgatgt tcctgcagat ttcacgttag
    66961 ctatcgaagc agctttaggt ggggcagccc agcatgtcat cgttgaaaat gaaaaagatg
    67021 ctcggcaagc catcacgtat ttgaaacagc aaagaggagg aagagcaaca ttccttccac
    67081 tgacgacaat caaaccaaga caattaccgg ctcatatatt gacacaagca gcagctgtag
    67141 aagggtttat agggattgcc agtgaacaag tcagttatcc cgatcaaatc caaactgtgg
    67201 ttcaaaacct gctaggaacg atccttttag ccaaagactt aactagtgcc aatgcaatcg
    67261 cgcaaacgat ccgctatcaa tatcgagtgg tttccttaga aggtgatgtg atgaatgccg
    67321 gaggatccat gacaggtgga gcgaataaac gaggaaacca aggcagtttg tttgtacaaa
    67381 atcaagaatt gaaacagttg actagtgaat ttgaagaagc agataaacaa ctccaagcac
    67441 aagaaaaaaa agttcaggag ctgcaacaag aaacagctcg tttagccgaa gaacaagaag
    67501 ttttgcgtac acgaggcgaa caattacgtt ttgaagaaca agaagcgaca aatcagctac
    67561 aaaacatcat aaatgaactt gaacgttttg aaaaagaaaa gcaaatctca acttttgaga
    67621 cacgtgaact gcagcagttt atcgaagatt acgaaaagca aacgaacgaa ttgaaagaca
    67681 aacaaacaga tcttgaatcg caacgacaaa aaatcgacga agaaatcaaa tcgttaagtc
    67741 aagaaagcga ccagatggaa gccagaagag cacaagtaca aagtcaaaaa gcacaagaac
    67801 aagcagatct tgctgtcttg aaagagcagt ttaatcatct gcagatccag ctccgcggtg
    67861 cccgagtcca aaaagcagag gcaaccgaac gtcaagaagc gatagaaaag cagttggcga
    67921 cattgacagc agacttttct gatcatgaag tcacagaaga aagtttggaa aaacaaatta
    67981 acgaattatc tgctcagcga gaaacattaa aagccgagtt ggcaaaagcc aaagagcagc
    68041 gagatagaag gcaaaaggag atcgataagc ttgaagcagt cttggcagag cgtaatcgtg
    68101 agcaaaaagc acgactgtcg gaacaatcca aattagaagt ccaaaaagac cgagctgaaa
    68161 tgattttaga taatcatttg acctatctgc agtcagaata tcagctgaca tttgagaaag
    68221 cttcccaaga ctatcaagaa acaaccgata tcgaagacag tagaacaaag gtttcatcct
    68281 taaaagaaca gattgaaaaa ctgggaccag taaacttaaa ttcaatcgaa caatacgaac
    68341 aagtcagtga aagacataca ttcttagcaa cacagcgaga tgatctgtta gcagcgaaaa
    68401 accaattgtt tgaaacgatg gatgagatgg atgatgaagt gcggacaaga ttcaaagaag
    68461 tatttgaagc tatccgtcaa gaattcaaaa ttgtctttcc aaatatgttt ggcggcggta
    68521 aagctgaatt agtactgacg gaaccaactg atttgctgaa aacaggtatt gagattgaag
    68581 tacaacctcc tggcaaaaaa ctgcaaagtc taagtttgct ttctggagga gaacgagcac
    68641 ttacagccat cgcgttgctc ttttccatta tccgtgtctg tcctgttccg ttttgtatct
    68701 tagatgaggt agaagcagcg ttagatgaag ccaacgtgaa acgttttggt cgttacttga
    68761 gcgatttcca agatgacaca caatttatcg tagtcacaca ccgcaaagga acgatggtcg
    68821 cagcagatgt actgtacgga gtgacgatgc aggaatccgg tgtatcaaaa atcgtttctg
    68881 tacggatgga agatatcaat gaagaggcga aaatcaacga aacgaaagtg taggaacgaa
    68941 aatgatcaaa ttagtagcaa tcgatttgga cggtacatta ttaaatgaac aaaagctgat
    69001 ttcagatgag aataaacaag cattagcaca agcaaaacag caaggggtca agatcgttct
    69061 atgtacagga cgccccttag ctgcgatggc gcattatctg caagaattag gactggtaga
    69121 tgaaggtgac tacagcatca ctttcaacgg cggtttggta caaaaaaatg atactggtga
    69181 aatcatggaa aagaaagtga tggaagtatc agatatccaa cgcttataca aactggctca
    69241 gcaattggat ctgccactag atgttttgtc tgacaatgtg gttttacagc tgcctagtgc
    69301 cccaaggaag caatccttgt acaatgtgtt gaataagctg ctgcaattcc aaccagcgga
    69361 tataagcgat attacagatg aatttgtgct taataaggca gtaatcgctt atgaccaaga
    69421 agaattagat cctaaaatca aagaaatacc agcagaattc catgaaatgt atgagatcat
    69481 caaaacaaga agtatgcttt tggaatttat gccaaaaggt gttacaaaag cttatggtat
    69541 ttctttattg gcaaaagatc ttggtttgaa acaagaagaa atcatggcga tcggtgatga
    69601 ggaaaatgat ttaccgatga tccaatatgc tggactaggc gtagcgatgg agaatgctgt
    69661 gcctttcgtc aaagaagcag cagatttcgt gacagccagc aatgaagaaa atggcgtagc
    69721 caaagtgatc caaaaatttg tattagagta gggggagtca aatgggattt tttgataaaa
    69781 tcaagcgtgc ttttactggc gaagagaaaa cagaagaagt tgaagtacag gagaagtacg
    69841 acaagggttt agaaaagacg cgtaaaacat ttggtgaacg gatgaatgag ttgtttgcca
    69901 attttcgaac agtcgatgaa gacttttttg aagaattaga agaaacactt atcggtgcag
    69961 atgtaggttt tgaaacagcg atacgaatca ccgaagcatt acgtcaagaa gtgaaactca
    70021 gaaatgcgaa aaaatcggca gaagtccaaa atgcgatcat cgagaaactt gtggatctct
    70081 atgaagcgga aggaatcaat gaagtaaatg aactaaatat ccaagaagac ggactaacag
    70141 ttattttgtt tgtcggtgtt aatggtgtag ggaaaacaac aagtattggt aaacttgccc
    70201 atcagttcaa aaacgaaggt aaaaaagtat tgatggcagc agcagatacc ttccgcgctg
    70261 gagcaatcga ccagttagtt gtctggggcg aacgcgctgg tgttgaagtt gttcgtggca
    70321 atgcaggagg cgatccagca gctgtcgtat tcgatgcttt ggaaagagca aagacagagc
    70381 aggcagatgt tttactagtt gatactgcag gccgactgca aaataaagtg aacttgatga
    70441 acgaattaga aaaaataaaa cgagtaatcc agcgggaatt accagaagca ccccaagaaa
    70501 cacttcttgt attagatgca accactggtc aaaacgcgat ggttcaagca aaacaattca
    70561 aagaaacaac agatgtgacc ggtcttgttt tgacaaaatt agatggtaca gcaaagggcg
    70621 gtatcgtact tgctatccgt aatgaattgc atttaccagt gaaattggtc ggtcttggtg
    70681 aaggaatcga tgacttggag ccgtttgatc caaatgattt tgtcgttgga ttgttcaaag
    70741 gattactaaa agaagaataa cccatgtcta aaaagcagga gctgtgacaa aagttgcagc
    70801 tccttgtttg aatgattgtt tttaacatag ctgtgttttt gatgccttca tttttatact
    70861 tatttgtaag cggttctcaa acaatttcgt tctttttctt agactttttg attataatta
    70921 gattcatatg aattggaggt cacttaatga tgaattttaa gcaattatta ttgcatgtca
    70981 atgcgcgccc ttttatcgac caagctcgat ttggtataga acgggaagga cagcgggttg
    71041 atcttgcagg aaatctagca aaaaccgatc atccagcaat ctttggcgat cgatcctatc
    71101 acccctatat ccaaacagat tttagcgaaa cacaaacaga gatgatcacc cctgttaccg
    71161 attctattcc cgaattattt cagtatctcg ctgctgttta tgatgtgact gctcgttcta
    71221 taccgaaaga agagatgatc tggccattaa gtatgccacc tgccttaccg gaaaaagacg
    71281 aagagatcat tattgcaaaa ttaaaaaatt tcgaagatgt cttgtatcga cgttatttag
    71341 caaaagaata cgggaagcga aaacagatgg taagcggtat tcatttcaat tttgaatttg
    71401 gcgatgagtt gctaagaaca ttgttcagcc atcaggaaga atttcaagat ttttccgaat
    71461 tcaaaacaga actttatttg aaaacagcga gaaactttat gcgctatcgc tggatgatca
    71521 cttatttatt cggtgcttca ccaatgagtg agaagaacta ctttttagat gaatcacatc
    71581 cgcaagaacc tgttcgcagt attcgcaaca gtgcgctggg ctatacgaat catccaaatg
    71641 tgaaagtttc ctatgcttct atgaaacagt atttagcaga tatcgagcga atgatcgaag
    71701 aagggaaact ttcggaggag aaagaatttt atacaccgct tcgtttccga ggcggaaaga
    71761 aagtcgcaga tttagcaaca acaggtgttc gttatattga attgcggaat atcgatttga
    71821 atccttatgc aagattgggt atcaatccag agcaagttcg gttcttacaa ttattcctga
    71881 tgtacatgtt atggacagaa gaaaaagaag actgtgacca atgggtagca gaaggtacga
    71941 ctcgaaataa caaagtagca ctagaacaac catcagatca aacagaattt catcaagaag
    72001 gtagagaaat tcttgaagga atgaagcaaa tgctggttga attggattgg ttggattctc
    72061 tttatttagt agaggaagca ttgactcaaa tggatcatcc tgaacaaacg ttagcagcga
    72121 aactctatca agaagcacag ctatcgagtc agcaagaagt tgctgtggca ttgggacatc
    72181 aatattataa agaaagccat gaacgtccct atcagttggc cggttttcgc gaaatggaac
    72241 tttctactca gatatttatg ttcgatgcca tccaaaaagg tgtccaagtc aaagtattag
    72301 atgagtcgga tcaatttttg cgtctgcaat tccaagacca tgtagaatat gtgaaaaatg
    72361 caaacatgac aagtaaggac agctatatcg tcccacttat catggaaaac aaaacagtaa
    72421 cgaaaaaagt cttaaaagaa gctgggttcc gggtaccagg aggcgcagaa ttttcatcca
    72481 tggaagaagc ggtaaaagct tatccgagat ttgccgagca ggcatttgtg atcaaaccta
    72541 aatcaaccaa ttacgggtta ggtatcacga ttttcaagga aggagctagt ctggaagatt
    72601 atcaagcagg tttagccatt gcttttcgtg aagacagttc ggttttagta gaagaattta
    72661 tgccgggaac ggaatatcgt ttctttgtga tcgacggaga agtccaagcc atcatgttgc
    72721 gagtccctgc taatgttatt ggtgacagta tccgaacagt gaaagaactt gttgaagaaa
    72781 aaaatagtga ccctttgcgt ggaacgaatc atcgtgcacc tttagaattg atccaattag
    72841 gtgaattaga acaattgatg ttgaaagaac aagggttgac gatcgaatca gttccccaag
    72901 ccaatcaaat tgtttatcta agggagaact caaatatcag tacaggtggt gattcgatcg
    72961 atatgactga tgaattttct gaagcttaca aaaaaatcgc cgtttctgcg gtagaagcac
    73021 taggagctaa gattagtggt atcgatttga ttataccaga taaagaaatc gatcctacaa
    73081 ctgataaaaa agcatatggg atcatcgaag caaatttcaa tccagccatg catatgcatg
    73141 tttatccttt tgcaggaaaa ggcagaagat tgacgatgaa tgtattgaaa ttgttatatc
    73201 ctgaagtatt ttaaaagaaa aagcttttga cagattgtcc tatttgatgt caatctgatc
    73261 aaaagctttt tttgcatgta aaaatttatg tgttttttcg ttttaaaata aacgatccca
    73321 gaagcttttt ttcttttttg gtttttcttt ttcagctggc gaagagtttt cttctgggta
    73381 ttttttttcg atatcaatca caggttcatt tactgcttct tttgctgtta agagcaatcc
    73441 gaattcctca ggatttgcag tgacgtaatc gttgactaca gtgaaacggc tattgttttt
    73501 cgttgctagc tggatatatt ggttttggac agaaaggggt agagccccat tcaagagtat
    73561 ggaagcatct ggatgttttt tgagttcttt taaaaagttt tctttgtttt ttggttggat
    73621 catttcagca acagtcatac taagatagca gcgttccctg aatgtcccta aatatttatg
    73681 ctgttcttca gggttcacta aaggtgtacc ataaagtccc ttatccaaat ggctttttac
    73741 atcatcttgt gccataaaaa ataccctcct tcttctcttt gtctttctta cgattatagc
    73801 atattcccaa taatacctaa aacatatgaa aaagcggttg cttttgttca acgattcact
    73861 taaaataaga atgaaaatca ttctcaatta gaaaggtgga ttggatgcgc tacggacgac
    73921 tagtagcatt attagttatt ttaagtagta tttcattgtt catcggagta tcgaatgtac
    73981 aattgtcaga actgctccag ttagatgggc aaagcttaca aatcttgcta gtgactcgtt
    74041 tgccacgaac gatttgtttg atccttgtgg gagcgaccag tagtatttgt gggttgatca
    74101 tgcaacattt gacccaaaat aaatttgttt caccaacgac tgcgggcacg atggatagtg
    74161 cgcgtttagg tattttagtg gctatgattt tcctacctgg tgcatccttg attgtccgat
    74221 ccttgacagc attttgcttt gcttttgcag gaacattgct ttttttatcc cttacgcgat
    74281 tgttcctcca gaaaaatcaa ttgatgcttc cgttgattgg agtcatgtta gggaatatca
    74341 ttggttcagt tgctactttt tttgcttatc aattccagtt ggtacaaaat atgacttcat
    74401 ggcttcaagg gaattttgcg actgtgatac gaggaaatta tgagttattg tatgctgttg
    74461 ttccattgtt gctcttggtt tggctatttg cttaccgatt tacgatcatt ggtctgggcg
    74521 aatcgtttgc agtaaatctg ggaatagatt accagaagat gcagttttta ggcattggct
    74581 tagtatcatt ggctagtgca gtcatgttga tcatggtagg aagcattcct tttatcggag
    74641 tgatcattcc gaatcttgtc tctagaatat atggagatca agtgcacaaa acaattggcg
    74701 taactgcttt agcaggtagt ttgttcttag tattttgcga tcttgtcgct cgcgtgttga
    74761 tttttcctta tgaaatacca gtcagtgtga tcgttggaat catcggtggg gctatcttcc
    74821 tttatcttct gataagggga cgacgatatg cttaaaaaaa agccatctat ttttattggt
    74881 atgcttgttc ttgttttatt tgttacagga atgtacttga cgatccatac atatggaaac
    74941 tggcattttg catgtgcatt gaggagtaag aaaatttttg catttatcct tgtctcgcta
    75001 gctgtcagca gtgccacaat cagctttcag acaattacgc ataaccagtt tttgactcct
    75061 tcagtattgg gacttgagtc gttatatgtc cttgtccaaa cggtcctttt cttctttatc
    75121 ggaggagtga cgatgcttca gcagacaggt acagtttttt tcttattgaa cgttgggctg
    75181 atggtcgggc tgagtctatt gttatttttc tttcttttga aaaaaatgag agcgaatctt
    75241 tttttattac tgatgtcagg gatgatttta ggtacgcttt ttggtagtgt cagtaccttt
    75301 ttacaagtca tcatggatcc gaatgaatat gatttgcttc aaggcagatt atttgcaagc
    75361 tttggcaata tccagagtca gtatcttttg cctgcttctt tgatcattat cggctgctgg
    75421 tacctgttat ttcgatatcg acatgtgcta gacgttttcc atctcggaaa tgaacaagca
    75481 gtaaacctcg ggatagacac agatcgtttt gaatttttga ttttatgttg tgtcagtctt
    75541 ttgacaggga catcaacggc tcttgtgggt ccagttactt ttttagggtt tattgtcgca
    75601 aatatcagtt atcgtgtctt ttctacttat cgtcatggtc agctatttat cggaagcttt
    75661 ctggtagcta tgctgtttct gacaggagga cagctcgcag tagagcagat tttcggctgg
    75721 aatacaacag tgagtgtcgt cgttgaattt gtcggaggaa tttattttgt cacaaaattg
    75781 attcgcgaaa ggaagagtat cctatgattg atttacaaaa ggtcaataaa ctgtaccatg
    75841 gaaaatcagt ggttaaagat gtacagttaa cgattcctga aaagaagttg actgctttta
    75901 tcggtccaaa tggtgctgga aagtcaacgg tgttgtcgat gatcagtcgt ttgataccaa
    75961 aagatacagg tgaaatctat ttagaccata acgaagtaaa ggcttggaaa tccaatgaat
    76021 tagccaaaaa attatcgatc ctacgacaat cgaatgaaat aaatgtccaa atcaccgtga
    76081 aagaattagt agaatttgga cgatttcctt atacgaaagg aaaattgacg acaaaagacg
    76141 aggaaatcgt tcaggaatca ctggaacaca ttgggttaga agaaatagcg gatcaatcga
    76201 ttgacactct ttcaggcggt caactccaac gtgcgtatat tgcaatggtg ctagcgcaag
    76261 acacggatta tattttactg gatgaacctt tgaacaatct agatatgaat tttgcggttc
    76321 aaatcatgca gattttaaaa aatttagtac aagaaatcgg gaaaacaatt gttattgttc
    76381 ttcatgatat caactttgct gcaagttatg cagacgaaat tgttgcaatg aaagatggac
    76441 agttatttac gcaaggaacg acccaagaaa tgataaaaaa agatgtattg gatgaattat
    76501 acgaaatgga catacggatt tgtgagattg aaggccgcag attctgtctt tatttctaaa
    76561 actaacatta ggagagaaga gatgaaaaaa ttagtagtag gtatcttgat tctagcatca
    76621 tttggtttag cagcatgtgg aaatagcaac aacaccagtc aggcagacac aaaaaaaagc
    76681 agcacacaaa ctgaaactac attgacgata acagatagta atggagacca aatcgaggtg
    76741 ccaaataatc cagaaaaagt cgtcgtattc gacaatggtt ctttagatac gatggatgct
    76801 cttggtgttg gagataaggt agttggagca gctacaagca gccttcctga gtatctttca
    76861 tcctataaaa aagtagaatc agcaggtgga ataaaagaac cagacttaga aaaaattaat
    76921 cagcttcagc cagatctaat catcatttct ggccgacaaa gagattttca aaaagatcta
    76981 agtcaaattg ctccgaccat tttcctttct ttagatgcga aaaatccatg ggaatctttc
    77041 cagcaaaatg tcactgcttt aggggagatc tttggtaagc aagaagaagc taaaactcaa
    77101 ttagaggaat tatctagtgc aatcgatcag acgaaaaaga aagcagaagc tactgacaaa
    77161 aaagcactag tcacacttgt gaatgaaggg caattatcag cctacggatc tggttctaga
    77221 ttcggtttca tccatgattt atttggcttt gaacaagcag atgatcaaat cgaagcatcc
    77281 actcacggtc aaagtgtttc ttatgaatat gtgctggaaa aaaatccgga tatcttattt
    77341 gtagtagaca gaacaaaagc tattggtgga gacgacagca aagatgatat ttctgccaat
    77401 gaactggtag cacaaacgaa tgctggtaaa aatcagcaga tcatctccct tgaaccagat
    77461 gtctggtatt taagcggggg cggtttagaa tcaatgaaac tgatgatcga agatgtgaat
    77521 caagcattta aatagcataa ataacagagg attaaactct catactatgt aacaataatg
    77581 tttcttacat tcttaaatag caagagccta tcctcaaaga agttatcaaa aaccatccgt
    77641 aaaatcgtat tgatgatttt acggatggtt tttatttatt tgagaaatct tttttcaacg
    77701 tgaattcatt atctacatca tacgggttga ttctagaatg gggagtggca aaaaatagtg
    77761 tgatccattt tttcagcatc aagatcgcct cctttgattt gaatcaaagg tacaaagcga
    77821 aacttagata aaacttaaat ttagatattt ttattttgta ccgatctctt ctttaaacga
    77881 tgttccatct gctgcttctc ggcaataagt ccactagact agaaaatatg agaagctatt
    77941 ttctgtccag cgttcttatt actcaaaaca aatcgcagtt gtcacaatct cttctaaacg
    78001 atgttccatc tgctgcttct cggcaataag cccactagac tagaaaatat gagaagctat
    78061 tttctgtcca gcgttcttat tactcaaagc aaatcgcagt tgtcacaatc tcttctaaac
    78121 aatgttcaat cagctgacct tcggtattag ctcaaagcac tgatttcaca acctctattt
    78181 aggcatgtgt ctcagcaagc ggttgatagt tgatgatctg catttttcga taaaaatcgg
    78241 cgggaagctt actccaccgt tttagtaatt gatagaaata actctcttct gctttgattt
    78301 tatactcgct taatatcaat ccaaaactat tcgttttttt tgaagctaat tttttataaa
    78361 tatccaatgc tttggtttta tcttcattga caaagagtgt ttttacttca atataagaac
    78421 cctcgatatt ttgtgtttct tcgataaaat agatgttttt tatatattcc ttcatagtga
//
LOCUS       DAXLPC010000004        62134 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.004, whole genome shotgun sequence.
ACCESSION   DAXLPC010000004 DAXLPC010000000
VERSION     DAXLPC010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 62134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62134
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.004"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            117..1436
                     /locus_tag="ACF3UE_000268"
     CDS             117..1436
                     /locus_tag="ACF3UE_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HFD3633729.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            1720..2472
                     /locus_tag="ACF3UE_000269"
     CDS             1720..2472
                     /locus_tag="ACF3UE_000269"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3633730.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(2494..3648)
                     /locus_tag="ACF3UE_000270"
     CDS             complement(2494..3648)
                     /locus_tag="ACF3UE_000270"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFD3633731.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            3833..6274
                     /locus_tag="ACF3UE_000271"
     CDS             3833..6274
                     /locus_tag="ACF3UE_000271"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFD3633732.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKPYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     KVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(6604..7308)
                     /locus_tag="ACF3UE_000272"
     CDS             complement(6604..7308)
                     /locus_tag="ACF3UE_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633733.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(7495..7740)
                     /locus_tag="ACF3UE_000273"
     CDS             complement(7495..7740)
                     /locus_tag="ACF3UE_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633734.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(7757..8608)
                     /locus_tag="ACF3UE_000274"
     CDS             complement(7757..8608)
                     /locus_tag="ACF3UE_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFD3633735.1"
                     /translation="MNSLTSTYRLLNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQPTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            8774..9778
                     /locus_tag="ACF3UE_000275"
     CDS             8774..9778
                     /locus_tag="ACF3UE_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFD3633736.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(10019..10375)
                     /locus_tag="ACF3UE_000276"
     CDS             complement(10019..10375)
                     /locus_tag="ACF3UE_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFD3633737.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            10743..11930
                     /gene="tuf"
                     /locus_tag="ACF3UE_000277"
     CDS             10743..11930
                     /gene="tuf"
                     /locus_tag="ACF3UE_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFD3633738.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(12118..14709)
                     /gene="mprF"
                     /locus_tag="ACF3UE_000278"
     CDS             complement(12118..14709)
                     /gene="mprF"
                     /locus_tag="ACF3UE_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFD3633739.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLVSVLPMIGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDP
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(14735..15496)
                     /locus_tag="ACF3UE_000279"
     CDS             complement(14735..15496)
                     /locus_tag="ACF3UE_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3633740.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            15663..16295
                     /locus_tag="ACF3UE_000280"
     CDS             15663..16295
                     /locus_tag="ACF3UE_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFD3633741.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMRSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            16354..17214
                     /locus_tag="ACF3UE_000281"
     CDS             16354..17214
                     /locus_tag="ACF3UE_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFD3633742.1"
                     /translation="MEKRQKMENQKVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            17399..19714
                     /locus_tag="ACF3UE_000282"
     CDS             17399..19714
                     /locus_tag="ACF3UE_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFD3633743.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            19896..21737
                     /gene="dnaG"
                     /locus_tag="ACF3UE_000283"
     CDS             19896..21737
                     /gene="dnaG"
                     /locus_tag="ACF3UE_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFD3633744.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            21761..22870
                     /gene="rpoD"
                     /locus_tag="ACF3UE_000284"
     CDS             21761..22870
                     /gene="rpoD"
                     /locus_tag="ACF3UE_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFD3633745.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            23087..25228
                     /locus_tag="ACF3UE_000285"
     CDS             23087..25228
                     /locus_tag="ACF3UE_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFD3633746.1"
                     /translation="MMKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDA
                     AMQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIE
                     KNEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHRED
                     TKEEHAKELLKMISEKIAQENKVEPEHEAEKDTEKDISGVNAAGKESLKTNDLKTNDL
                     KTDIPEKTETLSEKQSEDEKSNGLPEADKKEMLEKADKKATESDGINNEADAETQSAS
                     EDSTALEAKIEKEENQPELIEAETEPITIVPNTEKTPQESNPEKKDLDKTQKKKSKKV
                     PYLALAAVLLLGGGGWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFI
                     RADMIHQDLSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDH
                     LADDIKLKADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVV
                     DSATRDQYKTAKEAVEKVKNTDLSAQLNEQLQQVDKMLTDKEKKEEEEKKKAEEAKKA
                     EKAKKAAEEQAKQAAQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARAS
                     DIADASNPAWTWAPGVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKS
                     ALMKGIGESALPFYIVTINCKTGWFGGNGSN"
     gene            25424..26287
                     /locus_tag="ACF3UE_000286"
     CDS             25424..26287
                     /locus_tag="ACF3UE_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFD3633747.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            26392..26865
                     /locus_tag="ACF3UE_000287"
     CDS             26392..26865
                     /locus_tag="ACF3UE_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFD3633748.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            26961..27848
                     /gene="xerD"
                     /locus_tag="ACF3UE_000288"
     CDS             26961..27848
                     /gene="xerD"
                     /locus_tag="ACF3UE_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFD3633749.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            27867..28238
                     /locus_tag="ACF3UE_000289"
     CDS             27867..28238
                     /locus_tag="ACF3UE_000289"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3633750.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGVYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            28235..29005
                     /locus_tag="ACF3UE_000290"
     CDS             28235..29005
                     /locus_tag="ACF3UE_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFD3633751.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            28989..29558
                     /gene="scpB"
                     /locus_tag="ACF3UE_000291"
     CDS             28989..29558
                     /gene="scpB"
                     /locus_tag="ACF3UE_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFD3633752.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISFEEDVSPDLFFDGMNKGE"
     gene            29564..30280
                     /locus_tag="ACF3UE_000292"
     CDS             29564..30280
                     /locus_tag="ACF3UE_000292"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFD3633753.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      30362..30486
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            30609..31220
                     /locus_tag="ACF3UE_000293"
     CDS             30609..31220
                     /locus_tag="ACF3UE_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD3633754.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIP
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            31598..33121
                     /locus_tag="ACF3UE_000294"
     CDS             31598..33121
                     /locus_tag="ACF3UE_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFD3633755.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            33358..34698
                     /locus_tag="ACF3UE_000295"
     CDS             33358..34698
                     /locus_tag="ACF3UE_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFD3633756.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            34852..35589
                     /locus_tag="ACF3UE_000296"
     CDS             34852..35589
                     /locus_tag="ACF3UE_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3633757.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGNSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(35754..35975)
                     /locus_tag="ACF3UE_000297"
     CDS             complement(35754..35975)
                     /locus_tag="ACF3UE_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFD3633758.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            36006..37037
                     /locus_tag="ACF3UE_000298"
     CDS             36006..37037
                     /locus_tag="ACF3UE_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3633759.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYERILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            37024..38427
                     /locus_tag="ACF3UE_000299"
     CDS             37024..38427
                     /locus_tag="ACF3UE_000299"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFD3633760.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGFLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVIHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            38493..39128
                     /locus_tag="ACF3UE_000300"
     CDS             38493..39128
                     /locus_tag="ACF3UE_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFD3633761.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            39177..39857
                     /gene="cmk"
                     /locus_tag="ACF3UE_000301"
     CDS             39177..39857
                     /gene="cmk"
                     /locus_tag="ACF3UE_000301"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFD3633762.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            39992..41221
                     /gene="rpsA"
                     /locus_tag="ACF3UE_000302"
     CDS             39992..41221
                     /gene="rpsA"
                     /locus_tag="ACF3UE_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFD3633763.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            41403..42713
                     /gene="der"
                     /locus_tag="ACF3UE_000303"
     CDS             41403..42713
                     /gene="der"
                     /locus_tag="ACF3UE_000303"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFD3633764.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            42956..43231
                     /locus_tag="ACF3UE_000304"
     CDS             42956..43231
                     /locus_tag="ACF3UE_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFD3633765.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            43466..44512
                     /locus_tag="ACF3UE_000305"
     CDS             43466..44512
                     /locus_tag="ACF3UE_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633766.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            44514..45773
                     /locus_tag="ACF3UE_000306"
     CDS             44514..45773
                     /locus_tag="ACF3UE_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFD3633767.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            45779..46360
                     /locus_tag="ACF3UE_000307"
     CDS             45779..46360
                     /locus_tag="ACF3UE_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFD3633768.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(46442..47317)
                     /locus_tag="ACF3UE_000308"
     CDS             complement(46442..47317)
                     /locus_tag="ACF3UE_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3633769.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            47465..47797
                     /locus_tag="ACF3UE_000309"
     CDS             47465..47797
                     /locus_tag="ACF3UE_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFD3633770.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            47909..49117
                     /locus_tag="ACF3UE_000310"
     CDS             47909..49117
                     /locus_tag="ACF3UE_000310"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFD3633771.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            49271..49726
                     /locus_tag="ACF3UE_000311"
     CDS             49271..49726
                     /locus_tag="ACF3UE_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633772.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            50088..50363
                     /locus_tag="ACF3UE_000312"
     CDS             50088..50363
                     /locus_tag="ACF3UE_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633773.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            50376..52454
                     /locus_tag="ACF3UE_000313"
     CDS             50376..52454
                     /locus_tag="ACF3UE_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFD3633774.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            52617..54500
                     /locus_tag="ACF3UE_000314"
     CDS             52617..54500
                     /locus_tag="ACF3UE_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD3633775.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            54512..55459
                     /locus_tag="ACF3UE_000315"
     CDS             54512..55459
                     /locus_tag="ACF3UE_000315"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFD3633776.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            55479..56006
                     /locus_tag="ACF3UE_000316"
     CDS             55479..56006
                     /locus_tag="ACF3UE_000316"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFD3633777.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(56069..56722)
                     /locus_tag="ACF3UE_000317"
     CDS             complement(56069..56722)
                     /locus_tag="ACF3UE_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFD3633778.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            56854..57696
                     /locus_tag="ACF3UE_000318"
     CDS             56854..57696
                     /locus_tag="ACF3UE_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD3633779.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            57854..58750
                     /locus_tag="ACF3UE_000319"
     CDS             57854..58750
                     /locus_tag="ACF3UE_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFD3633780.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            58753..59466
                     /locus_tag="ACF3UE_000320"
     CDS             58753..59466
                     /locus_tag="ACF3UE_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFD3633781.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            59486..60004
                     /gene="msrA"
                     /locus_tag="ACF3UE_000321"
     CDS             59486..60004
                     /gene="msrA"
                     /locus_tag="ACF3UE_000321"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFD3633782.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            60001..60228
                     /locus_tag="ACF3UE_000322"
     CDS             60001..60228
                     /locus_tag="ACF3UE_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFD3633783.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            60380..60931
                     /gene="lepB"
                     /locus_tag="ACF3UE_000323"
     CDS             60380..60931
                     /gene="lepB"
                     /locus_tag="ACF3UE_000323"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFD3633784.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(61014..61556)
                     /locus_tag="ACF3UE_000324"
     CDS             complement(61014..61556)
                     /locus_tag="ACF3UE_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFD3633785.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(61793..>62134)
                     /locus_tag="ACF3UE_000325"
     CDS             complement(61793..>62134)
                     /locus_tag="ACF3UE_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3633786.1"
                     /translation="FYEKLGFKKNEEFSTEEAGSMVWDDTFWIMLLSHDFYKKFIKDK
                     EIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHEVDMGMPEEEMFSLEVQDLD
                     GNTLEPVWMKM"
BASE COUNT        21008 a        10752 c        12903 g        17471 t
ORIGIN      
        1 tgcctcacgg cagcttacaa ttactttttc atcttcaccc gttaagtgat gaaaaaagaa
       61 cccctttctg ctatggttaa agtgactaaa ccaaccaaaa gaaaggagtt cttttcatga
      121 ctagcttaca caaaaaccaa gtaaaattca attcaaatat cactatttct catacaggtg
      181 gtcaattatc gagtgattcg ggtctcgtcc tagtgaaaga gctgatgaac atctttggtt
      241 tttctgaact ggctaagcaa cacattcaca ttgaagacga acgagcgtat tttactcatg
      301 acaacttatc catacttgag cagttcatta tgcaattaat tgctggttac tcagctgatt
      361 ctgcagctaa tctcctgaga caagatcctg tgtttaaagc tgttttagat aggaaagaac
      421 tcgcttctca atcttcactt tcccgatttt tagatcgact atctgaggag aatatccatg
      481 aacttcaagc tttgaaccaa gaacttatcg ataaagcacg cctcatccgt aatgatacgg
      541 aattaatcat tgatttagat tcgacccatt cagatacatt tggtcaccaa gaacaaacga
      601 attataatac acactaccaa acctatggtt accatccatt ggtagctttt gacggattga
      661 ctggtgactt cttaaaagct gaactacgtt caggaaatca atatacatca aaaggcgtaa
      721 aggagtttct cacaccttta ttagagcact ataatcactc tctaccaaac actgacatct
      781 tggttcgtgg agacagcggg ttcgctacac ctggtgtgta tgattcgtgt gaatcaaaaa
      841 agagtcatta tgttattcga ctgaagaata atcgtagact aggtcaaata gctgagaaat
      901 cagtacttta tggcgataat caaaagtggg aagaacgaga agttcagtac ttctcgacca
      961 cttatcaagc acaatcctgg tcacaaagtc gtcgcgtgtg tatacgctca acacgtgaag
     1021 cgggcgaact actctttcga catgaattta tcgtgacgaa tctatcagaa aatgtttctc
     1081 ctgataccat cttttctatc tatgccaaac gtggcacaat ggagaacttc attaaagaag
     1141 cgaaagctgg cttttacttt gacaaaacag acagtcctcg ctttttggag aatcatgtcc
     1201 gaatgatgct cagcttgata gcttacaact tagtcaactt cttaagaacg attggctttg
     1261 aagaagtcca aaagggaatg accattcatt ctattcgatt gaagtttctg aaagttgctg
     1321 ggaaattagt ccaaacgggt agacgagtct atctcaaatt atctagttat catgtgtatc
     1381 agaatgaatt ctacagggtc tttgctcgcc tgaggcgagc cagtcaatgg atctaatcca
     1441 acaatctaac gattttttta ctgggaagtt atccagggag aagtatgctc aaaatgcctt
     1501 acacccaaaa tttattcctc aatatttttg aacagtgaat gtttgaagta actttttagt
     1561 caaaatcagt tgatagggat attagtgata catatttcaa taaaatgtgc caaagaatta
     1621 aagctatgaa ttattcagga aagagataga atagataaaa gaggagaata atttattccg
     1681 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
     1741 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
     1801 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
     1861 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
     1921 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
     1981 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
     2041 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
     2101 aagtcaagca aatggtgcgt gataatcagg gtagtggaat caatcgatga tgttttttat
     2161 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
     2221 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
     2281 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
     2341 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
     2401 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
     2461 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
     2521 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
     2581 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
     2641 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
     2701 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
     2761 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
     2821 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
     2881 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
     2941 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
     3001 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
     3061 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
     3121 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
     3181 accgacacct tgcgtcactt caccaccgct tgccaagccg taacgagcaa tatcacttgc
     3241 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
     3301 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
     3361 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
     3421 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
     3481 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
     3541 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
     3601 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
     3661 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
     3721 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaacaac tggaacaaga
     3781 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
     3841 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
     3901 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
     3961 gaaaaaagat aaaatcgatc aagtaatatt cggaaatgtc ctgcaagctg gtaatggtca
     4021 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
     4081 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
     4141 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
     4201 gctgaaaccg tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
     4261 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaaggttgc
     4321 aacacaattt tctgtgagca gagaagaaca ggatcgctat gccttgtcgt cccagttgaa
     4381 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
     4441 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
     4501 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcgcc
     4561 attgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
     4621 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
     4681 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
     4741 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
     4801 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
     4861 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
     4921 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
     4981 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
     5041 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
     5101 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
     5161 agtgagtgaa gtggaaatcc caatgggcat cgcgcagaat tttcaaatca atggtaagaa
     5221 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
     5281 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
     5341 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
     5401 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
     5461 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
     5521 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
     5581 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
     5641 tgctacagaa tcattggctt ctgcctgttg cgaaatccca ttcgaacgct tagggagaaa
     5701 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
     5761 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
     5821 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg attcacgcct acgcggcaag
     5881 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
     5941 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
     6001 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
     6061 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
     6121 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
     6181 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
     6241 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
     6301 gcaagattta cagttatttt atttactgca aatcttgctt ttttctctat cagaaaatat
     6361 gtttattatt agaatttttt atagttaagg ttaggcatct taagaaatca ggcaactcca
     6421 agatatcttc aggtagaaga gaagtcgcct aacattgtag gatcataggt gatttgttgg
     6481 acaggtcaag ctgatatttg agcctgatgt tagaaggaat ttctttttac ttgctgtaga
     6541 aattattata tgactaaaaa ggctgggatt ttaaatccca gccttttatg acaaatagaa
     6601 tttttatcga tcagtaatcg ctgtcgctgc aaattgttcg atcaaaggaa tcaaagtcaa
     6661 tttgactttg tatttccgtt cgagtgcttt ttcgataacg aactcatttt cagtagtcat
     6721 agaaatagtt gctaatttac gaggttcatc agcatttttt tcattaataa ctacttcatg
     6781 ttcattttgt tctgtgtaaa atttaggata ctcagcaacg gcttttgaaa aatcagcaaa
     6841 acttaaagcg gcattcgtat cagttgagcg tgtattttca gttgtgtccg cttttggttt
     6901 ttccgttttt tcttctggca cactgactgt ttcttctgta actggtgtcg caacagcttg
     6961 cgcagttggt tcatcgtttt tcaatcgttg atcattccag taagacacga tttcaataag
     7021 aagattgtca cggaatcgtt cgaaaatccc gttttctcct gaacgaattc tctttaatac
     7081 agtattgaag ttgtcatcga ttggcacgtt gatccgtgta tcttcatttg ttttcccagc
     7141 taatccgatc gttaagattt gacggttttt gggatcaagc atgacttgta acggcaaacc
     7201 atagcgtcgc aagctctctt cttctagaga acggaataat tgtcctctta caccatccaa
     7261 tgaaggacgg aattgattta ataatttttg tttctgtttt ttcttcatat gttctctcct
     7321 tcgctcatac cctttcgatt ataagaaaaa aacagccaaa tgaaaaggag taatgcaaaa
     7381 aaacttgcgt atacgcaaat tacaacagaa aaatttgcgt attttcccgt tttttgaaag
     7441 aaaaataaaa aatggaacgg attatgtata tatacataat ccgttccatt ctttctattt
     7501 tttcggtatc aaggcaaaaa caggtagttc aggtgaataa atgacttcat gttcgtgcca
     7561 gggtttgacc attagcgaat gatcgaaccg ttttttcagt tcttcgatga tttgatcatg
     7621 tgtccagttt cttgcaggaa aatgttggat tttctctgca tcgatcaaaa agacaaaatc
     7681 ggaatgaaaa gtctgggtaa cttcttccga gagagaattc aagcgttcga ttggatccat
     7741 aaaatcacct ttcgacttaa aattgggtag tatctgggtc ttttgctttg ccgactacac
     7801 catctaactg atcgatttgt ttcatttctt cttctgttaa ttcaaaatca aataattcag
     7861 tattttcttt gattctgctt ggtgtcactg acttaggaag aggaaggaat tcgtgttgca
     7921 gcgaccaacg caaagcaact tgtgcaatcg tcttgtcatg tgcttcagcg atttgtttca
     7981 tttcaggcac atcgaagatt ttaccagtgc ctaatggact atatgcttcg aggatcatat
     8041 catgtttttt tgcatactca actacagttg gctgtaattc gcctggtgca aggaaaactt
     8101 gattgaccat cggcataatt tttgctgttt ttgctagtgt atctagatgg tggggtaaga
     8161 aattgctcac accgattgct ttgattttac ctgcttcata cagttcttca aatgctcgcc
     8221 atgtatctgc atttgcttgt tcccaattat cacgaaaagc aacagggttt ggccagtgga
     8281 tcaaaaacag atctaaataa tctgtttgga gcttcttcaa tgattcttca aaagaagaca
     8341 tcacaagttc atagctgtgg tttgcattcc ataattttgt tgtcaagaat atctcttctc
     8401 taggaattcc actttcctta atcgcttggc cgacactttc ttcattcttg tatccttggg
     8461 cagtatcgat atggcgataa cctgcagcca gcgcttcttt aacagaggaa acagcgacat
     8521 ccccatcagg tgtttgccat gtgccgaatc ctactaccgg gatttcgtaa ccatttaata
     8581 gacgataagt gcttgttaat gaattcatac tttcagctcc ttttttattc gttcaactat
     8641 aagtgtagcg catttttcga aaaaaagaat ccattttgtt tctactcttg aaatttttgt
     8701 ttaaaagaaa atgattttga ttctggtatt tttgattttt tttccgtaaa ctaagacaga
     8761 agggaatgag aaaatggata tctatttaaa aaaagcaatt ctgcatatta ttgacagaga
     8821 aactggttct ccagtctttt cacaaaaaga gctggatctg acaaaagaat atattcgtga
     8881 ttttcttcaa aagaagatcc aaaaaatctc ttctgctcaa acaaaaactg gacaactagc
     8941 agaagaaagc atgatcgttg aatcacttaa aatcgctcaa gaaaattttg tggaagcaag
     9001 tgaagcaatc gttcagcggt ggttcgatat ctaccaagaa agtgaagaag cacctagtgc
     9061 agatgtattt gttgttttgt atgaattaga tacagtgatg tacttatctt tattgaaagt
     9121 caattatcgt gaggcttaca ctcactttgt tgaagcagac gaagcaggga tcgacaaccg
     9181 cttgattttg aatcgagcaa ttctaggggc gaaaacacaa aaagcagatg aagcattcgc
     9241 tgtgaatttg actgattgga cctacgaatt aattgaaaaa aaatatgagt tttctggcaa
     9301 aaaagagctt tatttttctg gaagagtgat cgaaagtgtt cctgcacctt ctttagaaga
     9361 aaatgtaaaa gtgatccaaa aagtagccaa gcatcttgga aaaaaatttg agacagaaga
     9421 atttgatatc atggctgatt tgaaagaagc tgtctatgat acgatagaag aaaaaggtcg
     9481 gttggatcat gagatgattg cggaaaaagt cttcaaggaa aacatcacgg caaaaatggc
     9541 ttttaaagaa gaagtacaag agcaaggatt tgtcccagaa gcacctcctg taaaagaagt
     9601 acaagaaatt tctgagaaaa aatttggaaa acaaaaattc aagctatcaa acgggatcga
     9661 actgatcgta ccagtagatg tatatcgcaa cccagatttg attgaatttg tgaataatcc
     9721 ggatggtacg atatccgtga tgatcaaaaa tgtggatgaa gtattgaatc gtttataaaa
     9781 atgactagaa cattaggtgt tcaagtacca gtgatcagtt aaatgaattg tgtcaagaga
     9841 aggatcggaa aagacgaata taacaaaaaa agagcgtgag acaaaagtaa agaacacttt
     9901 tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt cttatttctt
     9961 ggagttaaac gcttctgtcc cagcctcttt ttatctaata aaattttaag accatttact
    10021 aattatcgat tttttctgcc gcatttttag gcacttcaga agcctttatt tcttcccagc
    10081 ttaatacacc tttacgagga ttgactttga gtttaagata cgcattcatc tttaatggat
    10141 gttctctttc ttcgcgaagc gtcacctgtt ttttttcacc atctttatta taagccgctt
    10201 gcttgtaggt ataagtcgtg aatttctctc cgttatctgc ttgggtagct gacatttcgc
    10261 cattcgtcgt gatttttgta taataagctt cgccgccgta aaaataatga taagctgcaa
    10321 aacttccgcc gagaaatatg cctaaaacga caagtacgcc aattaatttt ttcatgtact
    10381 tcacctcttt ccttattatt aacgaaatag aagatttcgt ctattgaaag ttgttggcaa
    10441 cagctgaatt ttaaactttt cctcattttg ttcttattgc ttcaaaagaa agttaaggac
    10501 tatcttgaag tttttctcaa aaaacacatt tttttattta taaaaggtac ttttttcgcg
    10561 tataagacaa gcgagtgctc ttagttgact ttgaccaata ttgacgtata ataagcttag
    10621 ttcgaatctt acaaaaagta agtcggacgt attctttttg atttagtcaa aaaaagacta
    10681 taataaaaag gtgagagctg aaatttttca gtgatctata ttatttagga ggtttgtaaa
    10741 ttatggcaaa agaacattat gacagaagta aaccacacgt taacattggt acgattggac
    10801 acgttgacca tgggaaaact actttaactg ctgcgatcac tacagtatta ggcaaaaaag
    10861 gcctagcaaa tcctcaagac tatgctagta ttgatgcagc tccagaagaa cgtgaacgtg
    10921 ggattacgat caataccgca cacgtagaat atgaaacaga aaaacgccac tacgcgcata
    10981 ttgatgcacc aggacacgcg gactatgtga aaaacatgat tacaggggca gcacaaatgg
    11041 atggtgcaat cttagttgtt tctgcaactg acggtccgat gcctcaaaca cgtgaacaca
    11101 ttttattgtc acgccaagtt ggtgtaaaat acctgattgt tttcttgaac aaagttgatt
    11161 tagtcgatga tgaagaattg atcgatttgg tagaaatgga agttcgcgag ttattgagcg
    11221 aatatggttt cccaggcgat gacactcctg tgatcaaagg ttccgcatta aaagcattgc
    11281 aaggcgatcc agatgctgaa gctgctatta tggaattgat ggatacagta gatgaatata
    11341 tcccaacacc agaacgtgat acagataaac cattactatt gccagtggaa gacgtcttct
    11401 caattacagg tcgaggaact gttgcctcag gtcgtattga tcgtggtgct gttcgtgtcg
    11461 gtgatgaggt agagatcgta gggatcaaac ctgaaacaca aaaagcagtt gtaacaggtg
    11521 tagaaatgtt ccgtaaaacg ttagattacg gggaagctgg ggataacgta ggcgtgttgt
    11581 tacgggggat ccaacgtgac gatatcgaac gtggacaagt gcttgctaaa ccaggttcca
    11641 ttactccaca tacaaaattc aaagcagaag tgtacgtgtt gacaaaagaa gaaggtggac
    11701 gtcatactcc attcttcaac aactatcgtc cacaattcta cttccgcaca actgatgtta
    11761 caggaacaat cacattgcca gaagatacag aaatggtcat gcctggtgac aacgtgacga
    11821 ttgatgttga cttgatccat ccaatcgctg ttgaaaacgg aacgacattc tcaattcgtg
    11881 aaggcggacg gacagtgggt tcaggtatcg ttacagagat cgaagcataa gaaacgcgac
    11941 tcgaatattt tggtaatgaa aaatgtttaa aataaaagag cggtccaaac aggatttctg
    12001 tttggaccgc tctttgttct tcaattgtat aagaagagat tgtagaagca tgaactttcg
    12061 ttttacttca gtctctttta ttcatcatga gagtgttcat ctatcggtat gcagttttta
    12121 atactttctt cgtatccatt ttttcaaacc acttattcta ccttgtgtct gctcaactgg
    12181 cgcattatca ataatcagca aagcaatcat aacatatgca atccaactat ctctagaata
    12241 tagagtataa cgtgagaccc agtttgtagc gtacttgctt ttatattctc ttaatccatg
    12301 gaaagaataa aaatgagaac caaactcgta aaccaagtat gcaatccttt cctgtaaaaa
    12361 actctttctg gaagttccga catttgaaag aggggccatc cctaaattga accattggat
    12421 atgttcttct ttcatatagg caaacaaatg caagaacaag aaatccatac tgccagaagg
    12481 tgctttttta ggatcatatc gcatcagatc aatcgttcct actttattgt tcgtgtaagt
    12541 aggcatgatc gttgcaaaag cgacaatttc ttcttgggta tttttgacaa ctgcaatagg
    12601 cgctctttgt agataatctt cagagaaaaa gcctaaagaa aacccttttt cctttcgtga
    12661 acccaaccaa ttatcagaga tatttttgaa agtactcatt tgctcagtag aaaatggtgg
    12721 ttgtaagaca tcaaatgtaa atccttctcg ttcgatccga ttcaagacag cacgagtgcc
    12781 cttcattttt ttccctgaag ttgtaaaact attcaggtct acataagctt cttcccccat
    12841 cttaatgaaa tcgtagccga attcatgcaa aatcataaca atctcttcgc ttgtttcgta
    12901 gaaaactggt aaatagcata gtcgatctgt ttcttcgata aaagcttcga ttgcttctgg
    12961 aaaatcttct ttcttaccag aaggatcacc cattacaata catttattat tgaagcaagc
    13021 gaattggaga agaacagttg gttcaccgtc tttttcatag gcaaacatcc gcttatcttt
    13081 taagaagatc aattgactat cggagtttcc tccataagtt gtaaggatct tcagggcctt
    13141 ttcttcatta aaggcttcgc caatctgttt cttttctcct tgaaggaaat gaacaaatag
    13201 aacgatcatg aaactaacag cgatgatggc caacaatccc gaaaaccaaa tcttttcaga
    13261 aggaaataag aaaaaggaaa taaaatggtg acgccgatga gggaaatccg gcagattgta
    13321 taccccaata acgatgtaaa gcaaggacag tgcaccaata atgattccat cgatcgtacg
    13381 ccactcccat gaatagatca attgttcccg aaataattcg tttttagaag caagaatgat
    13441 cagaagcaga atagacaaga aaaccaccgg tgtgaaacta aaatcactta ataaaacata
    13501 aagtaaagct agaacaatca agaagattgt aggcaaatat gctcgtttca cacgtgctgc
    13561 gatccctctg cccataatga ttaaaagaaa tcccaatagt atactaggaa attggataat
    13621 aaaatgaaat ttcaatgggt tcaaactatg aagccagcga aactctgtaa aagcttgcgg
    13681 gatagtggca gaaagtacta gcatgattcc agaaaagtat aataagacaa ccacgatttt
    13741 atgcgcaatt tctgttgcta attgtttagg gataccagaa taacgctgat caaaagtgga
    13801 accgatattt ttgaagaaaa agacgattcc aatcaaaaac ggaatgatgt agtagaacag
    13861 gcgatagagc aagatccaca caacgactat ttctcttggc acaccaatag cggacaaccc
    13921 gataatcatc attacatcga aactcccaat ttctcctgga atcatagaca cgattcctat
    13981 cactgaagca gcaatgaata acggaattgt ttgccacaga tcaatccgga tttccattaa
    14041 ataaccaaca gaaaggaaac taaacaggac accggtccat tccaacaatg aaactagcaa
    14101 tagctgtcct tgagttttaa gtgaggtacc accaaggaat cctttctttt tgaaagtagt
    14161 aaataaaaag acgacaggaa aatatagacc gccgccgatc aaccatatcc aatattgctt
    14221 caaaaaagga gcaactggcg tgaagactac aagtaaaaaa gaaagcagac tgtaaataga
    14281 aagtccagcc atcaaaaaca agaaaacttt cgataatgct tggatcacgt ttctgctctc
    14341 tttcttttgt ccatatagtt cagagcgaag ccccacacta acaaacccgc cgaaaccggc
    14401 aatattgttg attgtattga tcagccagct tgtctcaaac aagtaacgag gattctgctt
    14461 ttgttcaagc atccgattca aaataatatc ataaccaatc ataggtaaca cagagacaag
    14521 accaatcaac agcataagtc cgcttttcca tacaggtata gtggcaaacg tttctcctaa
    14581 ttgctggata gatagagttt taccgatgga catcaattca ccgacaataa tgacaatgac
    14641 agaaatcaaa aagattgttt tgaacagtcc taggtggttt ttcagccatt gtatggtatt
    14701 ttttaacaaa taaatcacct tctattccta atagttatgt ttcagaaaga aattgaagaa
    14761 cttctcgatt gaagcgttca ggatcttttc tagctaattc atgtccttgt tctttcacaa
    14821 gcacaaagga agcttttggt atagttttag ctatatacaa agaatgtttt agcttgatta
    14881 catctttttt tcccacgatg atcaaagtgg gggagttgat tttttttaaa tcattttctg
    14941 taagcccgat gtcatgcagc aaaagtttga taactaaaag atttttgcga agacttgggc
    15001 gaaataaaga gagtaaccat acccatgcat aatgaatatt actgatgact ctggcagaaa
    15061 aacgaacgcc tttaacaagc gtgtttccag aatttaaaat caatcgatga acttttttag
    15121 ggaagctgct ggcaaatacc agtgctagat ttgctccatc actaaatcca agaaaatctg
    15181 cctgatcgat tttttccagc aacatgatcg tattcagatc ctcggccatt aactgaaaat
    15241 tcaacataga tgcttcgttt gtcgaacgac catgtcctcg gctatctact agatacacgg
    15301 tatagtagcg ttcgagtaca gggacctgtt ctgaaaaaaa gcggccgctg ccgtcattgc
    15361 catgcagtaa aaagagaggg aagccttgac cgctcttttc atagtaaatt tcgctcccat
    15421 ctggcatttt tgcatatttc ttttcttttt tcacataatc acctactgtg taaagtataa
    15481 cgattatatc agtcattggg caattgtttt tactgaaaaa caacgatcat tttcgtaaga
    15541 tgacaaaaaa tacaggaaaa ttcatttttt cttaaggcgt acacagaaat caaggaagaa
    15601 atagccaaga agataaagaa atagtaagat aaaaaaagat gtcaaaataa ctaggtgatg
    15661 aaatgaagcg aaaacgatta tctattatcc gtattctttt ttacatgatc attctgacgg
    15721 ttattggtgc ggtgttgttt ttaggaggaa gaacttatcg ttcggtaaaa cgagtggaaa
    15781 gctatcaaat agaaataaca acagctgcaa aaaattatca tatggaaaac tacgagaatt
    15841 tgatcaaggc gataatattg accgaatcaa aaggaaaagg gacagatctc atgcggagct
    15901 cggaaagtct gcatggagaa gctgagatca ttgataatcc agctgacagt attgatcaag
    15961 gtgtcaaata tttggcggaa atgatagtag aagcaaagaa acaaggatgc gatttatgga
    16021 cagctgtcca agcatataat tttgggaaag attatattgc ctatgtaaaa aatcatggcg
    16081 gagaaaacac agtagaatta gcagaagcgt attctaaaga tgtgctgagc ccacttttag
    16141 gaaatgagga agggaaacaa taccgatatt ggcggatcca gtccttgctt tacaatggcg
    16201 gctatctcta tcataatgga ggtaacatgt tttatcctga tattgtcaaa atgaatgaaa
    16261 aaataataga gacctatgaa aaagttttta agtaaaatag caggaaatgt tcaatcatga
    16321 ataaaattaa atgaaagaag gagtgcgcaa atagtggaaa aaaggcaaaa aatggaaaat
    16381 caaaaagtgg ggtacacaac caaagactgg atgttacggt ttgtgaaggg aatgtttatc
    16441 ggttcaggat ttatcttgcc aggagtcagc ggtggtgcat tagcagctgt ctttggcatg
    16501 tatgagcggc tgatttcttt tttagcccac cttacaaaaa atttcaaaga aaatgttttg
    16561 ttttttctgc ctgttggtct aggcggagtg acaggcatct ttctactttc ttttttagtc
    16621 agttttttat taggtgcgta tgaaacaacg atattatggt tttttgtcgg atgtatcgct
    16681 ggaactgttc ctgcgttatg gaaagaagca gggaaaaaag gaagagatac ttctgatgtg
    16741 atcatcatgg ttgttacttt tgttctggct tatttgtttt tattatacgg cgctcaatta
    16801 tttgacgggc aagtcgatca gaattttgga acatggctga ttgccggcgg attgattggt
    16861 ttgggtatga tcgtcccagg attgagccct tctaattttt tggtgtatat gggattgtat
    16921 aaagcgatgg ctgacggatt taaagaagta cgacttgaag tgattgtgcc gatcggaatt
    16981 ggtgggattc tttgtgttct tggattgtca aaaatcatgg attacatttt ctcaaaggca
    17041 tatagcaagc tattccattt cattttaggt gtagtttttg cttcaacgat tatgatcatt
    17101 cctaccgatt acgcgggatt gggagttgct ggggtactag cttgtcctgt tctttttata
    17161 gccggtacag cactaggttg gtggatgagc cgtttggagg aacaatataa gtaaagatag
    17221 attgataata aaaacagcac acgggtgatt caaacaaaaa ggttggcatc ttttttgtaa
    17281 aatcattcgt gtgtttttct ataaatttta taaaaacaag ttgtttttaa tcttggaaca
    17341 cgctagactt aaacacgtga ttatttttga aagttggcgg aaaatggaga aaaagaaaat
    17401 gaatggactt acacagcaag aggtagttca gaaaatggct tctggccagc aaaatgacta
    17461 ccaggaagat gcatcaaaaa gtacaaaaca aatattcagc gataatatat tgacgttatt
    17521 caattttctg aactttggta ttgggatttg tctgttattt gtaggtgcgt attccaacat
    17581 ggcgtattta gcaattattg tcgtcaatat cgttattgga atttatcaag aaatacatgc
    17641 aagaaatctt gtacggaaat tatcgattgt ttcccaatca gaagtactag tgatccggga
    17701 cggtaaagaa caatcgattt ctactaaaga gctggtatta ggagatttgg taaaaatcgg
    17761 agcaggagaa cagataccag ccgatttaca ggttatatct ggacgggcag aagcaaatga
    17821 agctcttttg acaggcgaat ctgatttgat tgtcaaagaa actggagctg aattgctttc
    17881 tggaagcttt ttgacaagcg gttctgtcat ggctgaagtt atccgagtag gtgcagataa
    17941 ttatgctgtc cgcttgacta gcgaggcaaa gactcacaaa gctattcgtt ctgaacttgt
    18001 agattcgatt cgcaaagtat ccaaattcac tagtttcgtg attattcctt tggggatcat
    18061 actatttttg gaagcactgt tcatccgcga tgcttctatc aaaatttctg ttattgcatc
    18121 tgcagcagct ttgttaggca tgcttccaaa gggtttggta ttgctaataa gtattgcatt
    18181 aacgacaggg gtaaccaaac tggcaaaaaa acgaatcctt gttcaagaca tgtattcaat
    18241 tgaaacgctg gcccatgtcg atacattatg cttggataaa acagggacca ttactgaagg
    18301 aaaaatgagt atccagcggg tagaagcact acatccgctg tacgagaaag ccatcccaga
    18361 aattatgggg acgtatctgg cagaaagcag tgataacaac atcactatgc gggctatgag
    18421 agattatttt gagctttcta atcggtatga tgtgacaaac aaagtcgcat tttcttctga
    18481 tcgcaaatgg ggcgcgatgg aatttccaga actgggagtc gtgtacgtag gagcgcctga
    18541 acgtttggtg gaagaagatc ggcttccgga cagtctaaaa acagcccaag cgaatggcta
    18601 tcgcgtactt atgttaggga tcgctccaaa tcagcaattg aacgaagaaa aaccagcatt
    18661 tgttgagccg gttgctctgt ttgaaatcga tgatccaatc cgaaaaaacg ctcaagaaac
    18721 actagcttat cttcatgagg aaggtgtgga tctgaaagtg atttctggag acaatccttt
    18781 tactgtctcc aatatcgcta gacgtgcagg attaccgaat tatgatgcgt atgtcgatct
    18841 ttctcaaatt actgaagaaa tggaagtgcg agaagctgct catcgctata cggtttttgg
    18901 acgagtgagt cctcagcaaa agaaattgct ggtaaatgaa ttgaaagaaa gcggcagaac
    18961 ggttgcaatg acaggcgacg gtgtgaatga tgttttggcg ttaagagaag cagattgtag
    19021 cattgctatg gcagaaggtg atggagcaac acgtcagatt gcgaatctgg tattgttgga
    19081 ctctgatttt actacattgc cagaagtcct gtttgaagga cgccgagtgg tcaacaatgt
    19141 gacgaaagtc tcaggcatct tttttatcaa aacgatttat tcatttattt tatcgattat
    19201 atgtgccgtt acagcaattg gatttccgtt tatccctatc caaatcacgc tgattgattt
    19261 agcgattgaa gggtatcctt ccttcttttt atcttttgaa caagataaaa gaaaaatcac
    19321 ttaccgttat ttgcctacag cacttattaa tgctttacca aatgccttgc ttgtagtagt
    19381 gaatatcatt gcggtgtatc tacttggaaa aacattcgca tggggaaatg ctgaaactac
    19441 tactttgatg tattacttgc tgattgggat cagttgcatg gcagttgtaa aagcttgtta
    19501 tcccttcaac ccattgcgca tcttcctagc agtaacgacg atcgtaggga tatatgtagc
    19561 tgcaatgctg ttccatggaa ttttggaagt aaacttaggg ttgggagaga gcgtaggata
    19621 cttctttgta ttcatgctcg taaatattgt tcttcgagta ttgtactgga aggctgatat
    19681 tcaaaatcag ttactgaaaa gagtagcaaa ttgatgctta atgagataga aatgtgttat
    19741 acttgaaaaa gcaatgaaat atgatacaat caaacatgta taattgtgtc ctttaaaatc
    19801 gcactgattt cagttagtgc gattttttac cggttattct cctgaaatat cttctgttaa
    19861 acccaaaaga tatcaataga gcagggggtg gaaaaatggc tcaacggatt cctcaagagg
    19921 ttatcgaaac agtacgcagt caaacgaata tcgttgaggt gattggacaa tatgtccagt
    19981 tgaaaaagtc tggtaaaaat tacttggggc tgtgtccttt tcatgaagaa cgtacaccgt
    20041 ctttttctgt tgcagaagac aagcagattt ttcattgctt tggttgtggt aagggcggaa
    20101 acgtgtttac ttttcttcaa gaactagaag gtctaagttt tccagaagca gtggtaaaag
    20161 tggcagactt cgaacagata ccgttagaag atcaatggcg tcagcgtact atagctgtcc
    20221 aaaatcctga atctgctacg gggaaactga ttgctgctca tgaaaaagca gcggaaatct
    20281 atcatcacat gctattgcat acaaaagctg gacagccagc tttagaatat ttgcaaagtc
    20341 gtgggttgtc tttagaatta attgaagaat tcaacatagg ttttgcacct aatgagcgtt
    20401 cttttcttca gcaagtattc aagaatgaat caatttcaaa tgaattgtta gaacgctctg
    20461 gattgtttgt cacgcatgat gatggccgta tgtctgatcg tttttatcaa agagtgatgt
    20521 ttccacttcg taattctcaa ggccagacga tcggtttttc aggacgctgg cttgcacctg
    20581 aaaaagggca ggaaaaagat cagcccaaat acttgaatag tccagaaaca gaactgttca
    20641 ataaaagaca agttttattt aatcttgata aagcaagaag cgatatccgg aaaaacggag
    20701 aaattttgtt gttcgaaggg tttatggatg tgattgctgc atggcaggct ggtatcaaaa
    20761 ctggattagc ttctatgggg acaagtctaa cagctcaaca gatccaacaa atggaaaagc
    20821 tgacgaaaga attggtcttt tgctatgacg gagacaacgc aggttttgaa gcaaccaatc
    20881 gagggattga attgcttcgg caaaacagtc gcttagcact ttctgtcgta gtcgttccag
    20941 aaaagcttga tcctgatgaa tatctccgta agtatggaga agcatctttc caagaattag
    21001 tggctcatgg gcgcgaaaca gtctttactt ttaaatcacg ttatttaaaa caagggaaaa
    21061 atttagataa tgaaaaagac aagatcgaat acctcgaaga attactagtt gaacttagcc
    21121 gagttgtttc accaatcgaa caagatatgt atctatctca actgtcaaca gagtttcaga
    21181 tcggcagaga gacgatacaa aaacaactgc gcgatcttcg aaggacaaat cagcaaaatc
    21241 gtcaagaacc tcaggaaagt caacacactc aggttacgag acaagaaact gcacggaaaa
    21301 agagaccttt gacgcaagta gaaaaggcag agcagattct attatatcgt gcatttaaag
    21361 aagtttctgt ccgtaatatt ttaaaagaac gagaatttca gtttattcat gatgcatatg
    21421 cagaagttta ttttttattc gatgcatatg tctcacaaca ttatgaattc aaccttgcag
    21481 agtttttaga ctttttgcaa gatgaaaatt taaggcggtt ggtggtggaa atcgaatatt
    21541 taccggtggc agaagaaagt tcgccacgag aaatccaaga cttgctagat gtgatcagca
    21601 aatctggctt agctgatgaa ataacattaa aaaaacaaat gcagcaagaa gccagacgaa
    21661 ctggaaacaa acagcttgag cttgaattga cgattgaaat catcaattta acgaaacagt
    21721 taaaacaagc caaatagcta ctcaaggggg gccttctttt atggcaaatg gaacagataa
    21781 aaaaacgtat gaagcagcag tagcagcttt catcaaagaa aacaaaccca aacgacaagt
    21841 tgtatatgat gatttatcca atcagcttgc tacaccattc actttgaatg cagatgaaat
    21901 ggacaaattg atccaaaaga ttgaagacgc aggtatcagt gtggtggatg aaaatggtga
    21961 tccatcaatt cacagcttga agagtgctga gaaaaaagct gaacaagcaa aaacagaaga
    22021 tctatctgcg ccaaccggtg taaaaatcaa tgacccggtt cgtatgtatc tgaaagaaat
    22081 tggccgtgtc tcccttttaa ctgcggaaga agaagtagcg ttagcattga aaatcgaaga
    22141 aggcgaccaa gaagcgaaac agcgtctggc agaagcaaac cttcgtttag tagtaagtat
    22201 cgctaaacgt tatgtaggac gaggcatgca gttccttgac ttgatccaag aaggaaacat
    22261 gggactgatg aaggcagttg aaaaatttga ctaccgcaaa ggatttaagt tttcaaccta
    22321 tgctacatgg tggattcgtc aagccatcac tcgagcaatc gctgaccaag cacgtacgat
    22381 ccgtattcca gttcatatgg ttgaaacaat taataaattg atacgtatcc aacgtcaatt
    22441 gctgcaagac cttggaagag aacctacgcc agaagaaatc ggtgcggaaa tggatcttcc
    22501 aacagaaaaa gtccgagaaa tcttgaaaat cgcgcaagaa cctgtttcac ttgaaacgcc
    22561 aatcggtgaa gaagatgact ctcacttagg tgatttcata gaagatcagg aagcaacaag
    22621 tccagcagaa cacgcagctt atgagttact aaaagaacaa ttggaagatg tactagatac
    22681 attgactgac cgggaggaaa atgtccttcg cttacgtttt ggtttagatg atggccggac
    22741 gagaacattg gaagaagtag ggaaagtatt tggtgttact cgggaacgta ttcgtcagat
    22801 cgaggctaaa gcattaagaa aattgcgcca tccttctcgt tcaaaacaat taaaagattt
    22861 cttagaataa gcatgaacta ttgaccagaa gagaaatcag taaaactgtt tggtttattt
    22921 taaaagaaaa aaagcttgag actacgcagt ctcaagcttt tttttctata ggaaggaaat
    22981 tcattcatta tttttaagta aatcctaaaa ataagctatt ggcgtgacgt atagaatatg
    23041 atagattaaa tggtagcgta aacctagtaa aggagccgat cgctaagtga tgaaaaaatg
    23101 tccaaattgc ggatcgaaaa aaatggagca gaatactatc tgtccagact gcggtcatca
    23161 aataactgca gaagatcagc aaataaaaga atcaattgaa gaaacaaata cagatgcagc
    23221 tatgcaggat aaatcaactg aagatgcagt ctttcctgat acagaattaa acgatccaat
    23281 cgaatggtcg gaattgaaag atttacctct agaatctgta atggaattat tcgaaaaagc
    23341 agaaccagaa gacgaagaac cacctgctca cgatcaagta actaatatag agaaaaatga
    23401 acagaagaaa gcaactgttc atgagacttc ggaagaatca ggaaagaatc aagaagaaac
    23461 gcttgaatca aaacaaaaaa gaagagtagc tgaactgaaa gaaatcgtcg ataatgagga
    23521 agaaaattcg atactatccg cttatatcaa agcacatcgt gaagatacaa aagaagagca
    23581 cgcgaaagag ctgctcaaaa tgatcagtga aaaaattgca caggaaaaca aagtagagcc
    23641 agaacatgaa gctgaaaaag acactgaaaa agacattagt ggagtaaacg ctgcaggtaa
    23701 agaatcatta aaaacgaatg atctaaaaac gaatgatcta aaaacggata tcccggaaaa
    23761 aactgaaaca ttgtctgaaa aacaatcaga agacgagaaa tcgaatgggt tgccggaagc
    23821 agataaaaaa gaaatgctcg aaaaagcaga caagaaggca acagagtcgg atggaataaa
    23881 taatgaagcc gatgctgaaa ctcaatctgc aagtgaagat agcactgctc ttgaagctaa
    23941 aatagaaaaa gaagagaacc agcctgagct gattgaagca gaaacagaac caataacaat
    24001 cgtgccaaat actgaaaaaa cgcctcaaga atcaaaccca gaaaaaaaag atttagataa
    24061 gacacaaaag aaaaaatcaa aaaaagtgcc gtatctcgct ttagcagcag ttcttctact
    24121 aggtggggga ggctgggctt attatgacca tcatcaaaaa gtagaagccg aagtagcagc
    24181 agaagcaaaa agacagcaac aaatggaaga acttcatgag aaacttgctg ccttttatac
    24241 agatgatcac catcaattta ttcgtgcaga tatgattcat caagatttat caaaactaaa
    24301 aaatgattta tccagtctta agaatgaaaa aggatattca gagttagaaa caacttacca
    24361 agatatccaa tctaagatcc gagatatcca aaaagtgaat gagtggttca tagcacctgc
    24421 catcgtcgat gatcatctag cagatgacat caagttgaaa gcagataaag agatccaagc
    24481 aatcgaaacg gataacacag attttggaaa attgattcaa caagcacaaa cagaagctaa
    24541 aaatcaatat gctgaattgc aaacagctaa agaaaaaaca gctatagtct ttaaagacgg
    24601 aaaagtagtg gattcagcaa cacgcgacca atacaagacg gcaaaagaag cagtagaaaa
    24661 agtgaaaaat acagatctat ctgctcagtt gaatgaacaa ttgcaacaag tagataagat
    24721 gctcactgat aaagagaaaa aagaagaaga ggaaaagaaa aaagcagaag aagcgaaaaa
    24781 agcagaaaaa gcgaaaaaag cagctgaaga acaagcaaaa caagccgctc aagcagcagc
    24841 tgcagctcaa gccgctcaac aagctgcggt cgcacaagca gcacagcaag aagcggcatc
    24901 ctcgacccct tcctcttcaa actcagcgaa tcagccaatc aaatctgcca gagcaagtga
    24961 tattgccgat gcatctaatc cagcatggac gtgggcacca ggtgtccaaa gcaaagtgat
    25021 tgctacatgt atccaacgtg gatatatcgt tgaaggagga tacagattag aaaaagccag
    25081 aatcgaaaat ggggaaggct attacaatct atatgccact tcaacaaaat ctgcattgat
    25141 gaaaggcatt ggagaaagtg ctttgccatt ttacatcgta accatcaact gtaaaactgg
    25201 atggttcgga ggaaatggga gcaattaatt ttaggcaaat gaaagaggct gtgagcctgc
    25261 cgtttaacac cgtttattcg aaaaagggga gtatgacaca actgttgtca tactcctttt
    25321 ttcacctttc caaaccaagg ctcagctatt caagtagata acattatgtt atgatagcaa
    25381 agaaatgtat taagaaaacc tttcactata gagggagaaa aaaatgaacg atttattagc
    25441 aactatattt acaggtatta ttattgatga aaatgaaaaa aactactttg tccaaaaaaa
    25501 cggacaaacc tttggcttaa gcaaatcaga aggtgaacac aaaatcggtg aagcagtgga
    25561 aggattcggc taccaaaatc aaaaacatga aaatcggatc actacacaaa ttcctaaaag
    25621 ccgtatcggt cattacgctt ttggaatcgt tactgctaca cgaaaagatt taggtgcgtt
    25681 tgtcgatatc ggtcttccag ataaagactt tgtcgtatct cttgatgaat tgccgacaat
    25741 gacagagcta tggcctaaaa aaggggatcg cttgatgatt tcccttagag ttgatgcaaa
    25801 agaccgtatt tggggcagtt tagcagatga aaaaatattc aaatctttaa gcaaatatgg
    25861 aacagaagaa atgaaaaaca aagatgtgat aggaacagca taccgcttga aattaacagg
    25921 tacgtacgtt ttaacggaag atttctatct tgggtttatc catccttctg aacgatataa
    25981 tgaacctcgt ctaggcgagc aaataaaagg tcgagtgatt ggtgtccgac cagacggtgt
    26041 actgaatctt tcattgaagc caagagcata tgaagctata tcagatgatg cacaaatgat
    26101 tttaaccatt ttagaacgtt ctgcagatca gcaaatcaac tttacagata aatcggatcc
    26161 agaagaaatc atgaaagctt ttggtatcag caaaggagca tttaagcgcg cattaggtaa
    26221 tcttttgaaa caaggattga ttacacaaga aaacggtgtg acaaaactag tcaaaaaatc
    26281 taattgagaa tcccttgcat gtttttctta actagcttat aataatttta attaacatag
    26341 tgttatatct ttttttattt gtaattatta taaattgttg gggttgagta aatggtcatg
    26401 aatgctattt cggcgatgaa aaaaacaaaa cagcagctac atgaagcggg gtttaagctg
    26461 acaccgcaaa gagaagctac tctgcttgtg cttttggaaa atgagaaaga gcatttatct
    26521 gcagaagaaa tcttcttttt agtgaaaaaa aagagtccgg aaattggact tgctactgtt
    26581 tatcgaaccc ttgaaatctt gacagaattg aaaattgtcg ataaagtaag ttttaatgat
    26641 ggattagccc gttatgattt gagaaaagaa ggcgccaaac atttccatca tcatttacta
    26701 tgcttgaact gcggcacgat cgaggaagta gaagaggatc ttttacttga agtggagcaa
    26761 gtagtagaag aacgttatca ttttttagta aaagatcatc ggctaacgtt ccatggaatc
    26821 tgtcaggaat gctatgaaaa agaaaaaaga aaccagtccg tctgagtgtc tagacggctt
    26881 tttctttgct cagattatgg aaaaagacta tcagaatgaa gcggtatctg atatgataga
    26941 gaggcatgag ggggattatt atgaaagagc aaatcaacga ttatctccac tacttgaata
    27001 ttgaacgggg attgtccgcc aatacacgac aaagctatga acgtgatttg gaacagtact
    27061 tgcattttct acaggagcag aaaattgctt catggcagga tgtcgatcgc tttttagtca
    27121 tccgttttct ggagaagttg catgaagaaa aaaaagcgac agcaactgtt actcggatga
    27181 tctcaagtct cagaagattc catcagtttt tacggcaaga gcgtatcact gatcatgatc
    27241 cgatgcaaca tatcgatacg ccgaagaaag cacagaaatt accaagtaca ttgactctga
    27301 cagaagtaga aaagctgatt gaagcacctg atacgacaaa aacgttaggg ataagagatc
    27361 gtgcaatctt ggaagtcatg tatgctacag ggatgcgcgt cagtgaattg attggattga
    27421 aattgggaga tcttcatctt tctcttggac tggtacagac agttggaaaa ggagataaag
    27481 agcggatcat tcctttaggt gattatgcga tccaatggct ggaacgctac ttagacgaag
    27541 cacgtccatt acttgtaaag gacgcatctg aaatgcatgt atttgtcaat aatcatggga
    27601 aaggtctttc tcggcaagga atctggaaaa atctgaagca gctagtacga gaggctggga
    27661 tttacaaaga agtaacacca catacgctgc ggcatagctt tgccacacat ctgctagaaa
    27721 atggagctga tttgcggaca gtacaggaat tgttaggtca cgcggatatc tctacgactc
    27781 agatttatac acatatcacg aagaaaagaa tgacggatgt ttataagcag cattttccaa
    27841 gggcttagtc ataggaaggt gagaagatgt taacacatta ccggaaagaa aaccgtaaaa
    27901 ttgctatggg actattgagt ttccataaga aactgacagg taaaacttct ttgttgaagg
    27961 agattgatac gtacgaatct gaagacgatt atgaactttt tttctttacg ccagaaggtt
    28021 caaccaacat tcaagggatt attggtgttt actgggcaac gaacgatcag ctgatcatcc
    28081 atgacatttc tttgaatccg tcttatcgcg gtgagaatat gggctttcaa atgttagatg
    28141 aattacagga aaagtacccg gatgtctcca tccgtgcaac tgaaatcaca gagccttaca
    28201 ttggaaaatg gctagcaaag aaaaagaaga aagagtgaat gagttgacgg agatcaatat
    28261 taaattagat gtattcgaag gtcctctcga tctgctgctt catctgattc agcaaatgga
    28321 aatcgatata tatgatatac cgatcgctac gatcacggag caatatatga attatatcca
    28381 tacaatgaaa acactagagc tagctgttgc aggagaatac ttagtgatgg ctgctacatt
    28441 gatggcaatc aaaagcaaga cattgcttcc tgtccaagaa ttcgtcacag atgatgaaga
    28501 attatgggaa gaagatcctc gagaagaatt ggtcactcag cttttagaat accgtaaata
    28561 taaatatgca gctgaaagac tgacagaaaa agcagaggaa cgaagtcttt attacacaaa
    28621 agaacctatg aacatcgatg ggttagcgga tgctgaaaag ccgttgaagc gaggacaagt
    28681 caaaaaaatc gatttgatcc gtgccatgca gaaaatctta gaacgtaaga aattttctca
    28741 aaaagtggaa aaaacgatca cgcccgatga cacaacgatc gaagaacgaa tggtatttat
    28801 cgaagagcgt ataaaaagaa atgcgcatgg ctgtactttc gattcttttt ttgagtcacc
    28861 ttctaaaagt gaagttgtca ctacttttat ggctttgcta gaattgatga aaaaagggca
    28921 gatcattgcg caacaaaaag aaaactatga atcaattatg ctttatccag cagtaggaga
    28981 taccgaacat gacgaaatta agtgaacttg aagcccttct ttttattgtt ggcgaggaag
    29041 ggatcagtaa tgaagaatta agcggactgt taaatctcag cgaagcagaa gtcacaagtt
    29101 tagtgaaaga attaaaagaa tcttacactc aaaactcgca ctcagctttg catatttttg
    29161 aaacggaaag ccattatgta ttaacgacta aaaaagagct ggctccctta cttaagcgat
    29221 atgcgcaagg gacatcaaac acattatctc aagccgctgt cgaaacctta gcaatcatcg
    29281 cttataaaca gccaatcaca agagctgaaa tcgagcagat tcgaggagtt caggtttcag
    29341 gagcggtaca gcgtctagct gcccataaac tgattgaaga aaaaggtaga gtagaagggc
    29401 caggtcggcc gatattatat ggaacaactg gctacttctt agattatttt ggtttgaaat
    29461 cattagaaga actgcctgat acacaagaaa tggaaatttc atttgaagaa gacgtgtcac
    29521 cagatctatt ctttgatgga atgaataaag gagaataatt gtaatggaaa gattgcagaa
    29581 agtaattgcc cacgctggca tcacttctcg tcgaaaagca gaagaattca tccttgcagg
    29641 acgtgtaaaa gtaaacggac aagttgtaag ggaattaggg ataaaagttg ggaaacatga
    29701 cactgtggaa gtggatgaag tcccaattta tcaagaagaa tacggttatt atttattgta
    29761 caaacctaaa ggagttattt ctgctgttgc agatgacaaa ggaagaaaag ttgttacgga
    29821 tcttttgccg atggtaaaag aacgtatcta tcctgtaggt cgactggatt acgatacttc
    29881 ggggatcttg ctactgacaa atgatggaga ttttgctcag cgcctgacac atccaaaaca
    29941 tgaagtggat aaagtttacg ttgcaaaggt aaaagggatc gctacaaaat cgatgcttgc
    30001 acctttgaca aaaggaataa agatcgaagg acgaaaaaca tctccagcta aattccaaat
    30061 tttatcagtg gatcctaaga caaaccacag tatcgtggaa ttgacgatcc acgaaggacg
    30121 taatcatcaa gtgaaaaata tgcttcaagc agttggtctt cctgtgcaaa aactaaaacg
    30181 tgaaaaatac ggagatctga ctttacaagg cctacgtcct ggagattacc gtgaactgaa
    30241 caaaaaagaa gtcagcagtt tgctgaacca ctcaaaatga acacttactt tttataagtg
    30301 ttagatgttg cgttttttga atagatatgt ataatgaata tgtaaacaaa aattatataa
    30361 ggttcgtctt caggggcagg gtgaaattcc cgaccggtgg ttatagtcca cgacctattt
    30421 tgcaaaaaat agctgaatcg gtgaaattcc gataccgaca gtatagtctg gataaagaag
    30481 atagagctta tttgacgacg cttgatcaaa taactctaac tctattttcc ctggaaaata
    30541 gagttttttc atttggagag aaacgtcaaa aagttcgctg aagaggagtc ctaacaggag
    30601 gatttcaaat gaagaacacc cgtgtacaga aaatggttgc agtagcgatg tttgctgcga
    30661 tcgcgttagt tttacagtat tttgcttttc cgatcatgcc ggcttttagt tttttgaaga
    30721 tcgattttag tgatatcccg gtattgatca gcatgttctt attcggtcca gcggccggag
    30781 ttgcaacagc gttcttgcgt tcagtattac atctgctgac tacaggtttt tctccggata
    30841 atttggtagg agacactgct agtttcttat caacaacgat ctttacattc ccgatttatt
    30901 atttctttag tgtaaagaaa cagcataaag gaagaaacaa atttttaggt gtcattacag
    30961 gaaccatcgc tctaactatt tttatgagta tcgcaaatta tttcgttatt acgcctcttt
    31021 acttaatgtt tttaggactg aacgcaacac agatgctagg catgtcttta gcaaactatg
    31081 tactgattgg gatcgttcct ttcaacttga tcaaaggatt catcgtgagc gctgtctttt
    31141 tagtgctgca tgcgcaactt cttccatggt taagtcgaaa acaacatcag ttcgaacaac
    31201 gtcatacagc agtcaaataa ttatcaaaaa gatcaagaaa tttcttggtc tttttttttg
    31261 gaaaaaaata caagacatgc aataatgtaa acgttttatt tgtttgtttt gagtattttt
    31321 ttgatttatg cataaaaatc aatcaattct ttgcaaatgt gaaattcttc tccttttaaa
    31381 agacgaaaat gtttgtttat aaaaaaaagg aaacgctaca atgaaaaaga agaaagcttt
    31441 aaaaacctga aaaaagagga gggaataggg aaaaacgaac tttttgaaca aaagttttac
    31501 aaaatgcgtg ttattatttt tgttctgata ctctttttga taaaataaca ttagagccaa
    31561 aattgttgtc tctaacggaa aagaaaggaa gaagaagatg gaacaaacaa aaaagaaaaa
    31621 atttcaaatg ccttcagcgt atacggtctt atttattatt attgcagtaa tcgctgtact
    31681 tacttggttt ataccagctg ggcactatag tgtagacgat gcaggcaaca tcgtcgctgg
    31741 atcatatgaa cgagtacaac aaaatcctca agggctgtgg gatattttca tggcgccaat
    31801 caatgggatg ttaggtgtac cagcggggga gctaactaaa gaaacacctg ctgcaatccc
    31861 aatctctttc ttcattttgg ttgttggtgg atttttaggt attatcaaca aaacaggggc
    31921 actagatgcc gggattgctt cagttgtgaa gaaattcaaa ggaaaagaaa aaatgcttat
    31981 tccagtattg atgctgttat ttgcattagg cggctctact tacggaatgg cagaagaaac
    32041 gattccattc tatgctttac tgatcccagt tatgatggct gtaggctttg atacagtagt
    32101 agcagtagca atcgtattag tagggtctca agtaggctgt ctagcttcaa cggtaaatcc
    32161 ttttgcaaca ggcgtagctt cacaagctgt tgggatttcg atgggtgaag gtattggtct
    32221 tcgattcttg atgttcgtta ttttgttagc tatttctatt gtatatgtgt atcgttatgc
    32281 atcaaagatc gaaaaagatc caacaaaatc attagtatac aaccaacgta aagaagatat
    32341 gaagcatttc gatattgaag caatcggtcg tcaagaagta atcacgaaaa aacaaaaaca
    32401 tgttaatgta ttgttcttta ttacttttgg tatcatgatc atcagtttga ttccttggac
    32461 aaccttgaat gcgaatttca cgatttttga atcattgaca aactggttaa caaaccttcc
    32521 ggtactaggt actgttctag gtaaaagcat gcttccatta ggtgactggt acttcccaga
    32581 aattactatg ttattcttag taatgtccat cgtagtagca atcacttatg gcatgaaaga
    32641 gtctgaattt gtctctgaat ttttagctgg tgcttctgat ttgatcggtg tagcaatcgt
    32701 agtagctgtt gctcgtggta tccaagtggt tatgaacaat ggattaatca cagacaccat
    32761 cttacattgg ggcgaacaag gattaagttc attatcttca agtgtattca tcattattac
    32821 atttattttc tatatcccta tgtcattctt gattccttca acttccggct tagctgctgc
    32881 aacaatggga atcatgggac ctatgggtga atttgccggc gtcggtaagg atttagtaat
    32941 cactgcttat caatctgcat ctggtttagt aaacttaatt acaccaacat ctgctatcgt
    33001 aatgggtgct gtagcaattg ctcgtttcga tgtttcagtg tggtggaaat ttaccggtaa
    33061 attaattgcg atattatttg tagccatctg tgtgatccta ggtgtagcag caatgttcta
    33121 aacctagaca aatacaggta caaggtctat cataagaatg aagaaaccga taaacggcta
    33181 tcgataagca cgtggacaag tcaatagctc cattcagtga gtgttttttc tttcatcatt
    33241 tgttaagaac attctgcttg ctgatggagc aggcttaaaa cgtcattatt tgagaagaag
    33301 aggttgtgtc ggaggaattt gacatgaccc tttttaacat attaggagga taatatcatg
    33361 aaaaaatttg tgacagaaca acatcatgaa caagcattag aatcattgag cgaattgatc
    33421 cgaattcctt ccgtactaga tgaagcagat tcaggacaag gacatccctt cggtaaaaaa
    33481 gtgattgaag ctttggataa agtattggaa atcagtgaaa agctaggatt tagaacattt
    33541 aaagatccag aaggctatta cggttattca gagattggct ctggagatga attattcggt
    33601 atcttgtgtc atatggacgt tgttccagca ggggacgaaa ataattggga aacaaaacca
    33661 ttcgatccaa ctataaaaga cggctggtta gttggtcgcg gatcccaaga tgacaaaggt
    33721 ccttctattg cggcaatgta tgccgtcaaa gctttgattg atgctggcgt ggaattcaag
    33781 acacgtattc gttttatctt tggtacagat gaagaaaatt tatggcgttg tttagaaaaa
    33841 tataacgaaa aagaagaagg aattacgcaa ggatttgcgc cagatgctga atttccttta
    33901 atttatgcag aaaaaggctt attgcaagct tacttgacag gaccaggaac gaacgagttt
    33961 tctgtaaaag ctggaggagc gttgaatgtt gttcctgatg cagctcctta ctctggagaa
    34021 aagctttctg aagtaaaaga agcgttgaaa aaacacgaat tcgatttcga agaacaaggt
    34081 gaaggcatcg tcgttcttgg taaaagtatc cacgcgaaag atgcagcaca aggagtgaat
    34141 gctatttctc gtctggcaat tgctctttca gaagtattcg attttggccc aatcaatttc
    34201 ttaggaaaat tagttcaaga aaatgcaact ggtgaagctg tcgtgggcaa aacagaagat
    34261 gaacaatccg gcgagctaac gatgaacttt gcaagtttgg aaatcacacc agaacaaaca
    34321 aaaatcggtg tagatatgag aatccctgtt acattcaaga aagatgattt agtagctaaa
    34381 ttaactaaaa cagcagaaaa atatgggttg acttatgaag aatttgactt ccttgattca
    34441 ttatacgtgc cactagacag tgagttagtg aaaaatctat tggggacata tcgcgatatt
    34501 actggagaca tgactgaacc gtttgtatca ggcggcgcta cttttgctcg tacgatgaac
    34561 cagtgtgtgg cattcggtgc gatgttccct gatactcctg actttatgca ccaggcgaat
    34621 gaacgatggg aattaagtag tatgtataaa gcaatggaaa tttatgcaga agctgtgtat
    34681 cgtttatgtg ctaaataaaa ataaacatac aaaaagggcg gatattcaaa tggatattcc
    34741 gtcttttttt atttgatgct ggaaagtttg catttctctc ttattttttt taaggtataa
    34801 tcatacttga ttaagaaaaa ggggtcactc agatagaaaa ggtgggagaa agtgaaaata
    34861 tttagacgaa tactaattgg cttagtcatc attttaggat tactcggtgg agccggttat
    34921 tactatatac agcaaaatac gtacgaacca tcgtcagaag cgcaagtgtt ggtaaaagaa
    34981 ggaaaaaaca aagaagatta cttatttttt gaaggagaga aaaagaatca tggaaattct
    35041 ccattactta ttttttatcc tggtgctctc gtagagccag aaagttatag tatttgggcg
    35101 caagatttag caaaaaacgg cttttcagtc gctattgtca aaatgccact tgatctagca
    35161 gtgatgggcg gaaacaaagc ggataaggtc aaagaagatt ttccaaattc cgattatgtg
    35221 atcggtggcc attcattagg tggcgtaatg gcaagtcgtt atgtcaataa gaatcattca
    35281 gacaaacatt taaaaggggt attcttcatg gcaagttatc ccgacaaaaa aggaacattg
    35341 acagaatcag ctgttcctgt tttatcgatc acggcgacaa aagataaagt attgaatcag
    35401 gaagcttatc aagaagctaa gcagtattta ccggaaagaa cagagtatgt atcaatcaat
    35461 ggcggaaatc atggaggttt tggcagctat ggtgagcaaa aaggagatgg agaggcagaa
    35521 atttctaacg cagaccagca aactgtgatc gtcaatacat tggaaaactg gctgaaaaag
    35581 ttgaaataat ataaatgggt cctatagggt ccgtgaaaaa actagtcaat taactataga
    35641 tagcaaatga atctttcaaa ataagtcggg atttcacgga acaagagaaa cagatcccgg
    35701 cttattttca agtttagaga acttagtgta cgtttttaaa gtttcgttta tatttatatt
    35761 ttattttcta ataaaatcgc tcgaactgga catttttgat acgctttttt tacatatgtt
    35821 tcttcttccg gcatcacgaa ctgttgatga gcctctggtt cttgggcaaa taaaacgatt
    35881 ccttcttcat cataatcgaa aatatctggc gcttcgattt gacaaagacc gcatgcaata
    35941 cagcgttcag gtacaagttt acatagtagt gacatttcta accatcctaa cttaaggaga
    36001 ataatatgat tgtttttatt ttatcgctat tttcatcagg acacaagctg cggattagtt
    36061 ctctttacca actccttgtg ggaaaacgaa cgacttcagt acttatttat ggatttaccc
    36121 acgaactttt gtttatccat aacagttttc cagaattgaa gcaggataag ttttatcaaa
    36181 ttttgcaaaa aattgcgcag caaggttgga tcgaaataaa tgaaaatgaa gcaaagctaa
    36241 cgcctgcagg ggctgatatg ttgtccgaac atcaaataga acatactggt ttgcgttttg
    36301 accgctatgg cagaacaggg gaaactagtt ggcggctcat taaatttgct gttcaagtaa
    36361 tttctaatct ggcaacgggt attcaagact atcttccagc agagacaagt cctttttata
    36421 ctttccaact aaaaaaatgg cttagtgaaa gccaattgcc acgtgaaatt ttgattgata
    36481 ctgcgtatga gagtttggtg cagctgtttt cggagatacc agaagaagca gcagattttt
    36541 tagctaacca attatctgga aatgagcgaa cagggctgct tccttatcag ctggcaaaaa
    36601 acaatgatga gtcagcggtt tatctgcaac aaagcagatg tatccacctt ttgttagcac
    36661 aaatcgaaaa acggccagat tcgctttggc acgctttgat cgattcatta ttacagcaaa
    36721 atttcaatca aagcatgatg atcaccaagc agatgtttat gaatggtcag acaattgacc
    36781 agattatggc aatccgtcat ttaaaaagag gaacagtaac agatcatctt attgagtggg
    36841 ccttgttttt tgatgatttt ccatacgagc ggattctctc tgcagaaaca atcgaacgtt
    36901 tggaaccaaa taaggattcc gtgcgagagt ggcgctttag cgaatggaat gtagatggac
    36961 aattagatta tggagaattt cgtttgtatc aaatctatct attgagaaag gaagcgatac
    37021 agaatgttaa taaatgaatt aaaaaaatat tttggatttg attcatttcg tcccggccaa
    37081 gaagaaatca ttcaggcgtt gcttgatgga gaagatactc tcgctatttt gcctacagga
    37141 acgggaaaaa gcctttgcta tcaattgacg gggtttttaa tggaaggtct ggtcatcatc
    37201 gtgtcaccgc tgctttctct aatggaagat caagtgacgc aattacaaaa acgaggggag
    37261 aaacgagtag ctgctttcaa tagtttactt tcgcaatctg aaagaagata cgtcctccgt
    37321 catctatcgc aatataaatt tttgtttttg agtcccgaaa tgttgactaa tccttctctt
    37381 ttagagcatc tgaaaaaaca aaatattgcg ttatatgtag tagatgaggc tcattgcgtg
    37441 tctcaatggg gagttgattt ccgtccagaa tatcaacagt taggaaaaat ccgaaagctt
    37501 ttaggaaacc cggtcacact ggcactaacg gcgacagcaa cagatttagt agcaagagat
    37561 atacgtcatg tactatttga tcgaccacca aaagagatca gacaatcagt caatcggcaa
    37621 aatatctcgc tttttgttcg gaaaacgcag caaaaagaac aagaacttga acacttcatg
    37681 gaaagagcac aaggagcggc aatcatttat tgtgcaacaa aaaaagaagt cgaacgattg
    37741 tatcatttat tcagggaacg ttttacagtt ggatactatc acggtggtct tgatgcagct
    37801 caaagaagac aacttcaaca gcagtttgta aaaaatcagc tgcagtttct cattgctacg
    37861 aatgcatttg gtatggggat cgataaatct gatatccgtt atgtgatcca ttatgatttg
    37921 ccagacagtc tagaaaacta tgtacaagaa atcggtcgag caggcagaga tcaggaagaa
    37981 agtgcagcaa ttctttttta tcaaagtggg gatgaacgta tccattattt ctttaatcaa
    38041 ctttctagag aacagcgaca aagttttgag ctttatttgg aatatgccac agagcaagct
    38101 ccctttgatg agctgcaaaa aaaatggatg gagctgatcc agcagtctga aaaaccagaa
    38161 aattgggtgg aacggctcaa acgtcaggaa aaagaaaaag aattccgcct gcagcagatg
    38221 cttcgctata ttaatgaaga aaactgccgc agaaaattca tcttagctta ttttggcgaa
    38281 aaactctccg aaaagccgca gaattgttgt gatattgatg gagcaaaagc agaacttctg
    38341 ccaaagagga agcttttttc taagactgaa caacttcatt gggaaacgat tttactaaat
    38401 ttatttaaaa aaaacatgga acattgattt tttaggacaa gacacttttt cctatggtat
    38461 aatacacacg atagagttta ggaggtaaaa cagtgagcag aaaagataga catcaatcta
    38521 cagaaaataa cgaaacacaa gaaccatggg aacaaccaat ctacgataca gatgatgaag
    38581 tttcatcaag aagttctcag agacaacaaa agaaaggaaa tacattattt ctttcgctat
    38641 ttttgatttt actggtctta tgtatcgcta ttccagcagg tgcttatttc tggatcagaa
    38701 atggatcaag caacaatgca acagcagcaa cttcttctga aacttcgaca tcagtagtag
    38761 aaagttctac aagtacaaca aaagaggagt caactgagac ttcaacagta gaatctagta
    38821 caatcgcgga agaatctact gtgtctcaag atacaggtgt aacgtcagaa agcagtattg
    38881 cagcagagac aacaccgact tcctcaagtg aggcaactta tcaagcaggg gattcaagca
    38941 gcaatgcagc agaaacaaca ccttcttcat cagctgcagc cggttcaaca acgactgttc
    39001 aagcaggcga aggtccaaaa caagtggctg agcgtgcagg gatcaccact gatcaattgt
    39061 ttgaattgaa tggcttagat ccaaacaact ttatgcttta ccctggtcaa gaattaagaa
    39121 ttaaataata atagccgcgc tttgcggctt tttttctgag aaaaaggagt tatatcatga
    39181 cacaaatcag tattgcaatc gacgggcctg cttcatctgg gaaaagtacc gttgccaaga
    39241 tattagcaaa agaattgaat tatatttata cagataccgg tgccatgtat cgcgcagtaa
    39301 cttatttagc tattacgaac aatgtatctt tttcagatga agaagggcta gtttcgctga
    39361 tcaaaaagta tcctatctct ttttcgcaac aagaagatgg acagcatgta ttcatagcat
    39421 caaaagatgt gactttagaa atccgtcaac cagatgtcac aaaagctgtt tctgaagtct
    39481 ctgcacatgg aaaagtcaga gaagaattag ttgctgtcca acgaaaaata ggggaacgcg
    39541 gtggcgttgt catggacgga agagacatcg ggacagctgt attaccgaat gcagaagtga
    39601 aaatcttttt agtagcaagc gtaagtgagc gtgcagaaag acgtttcaaa gagaaccaag
    39661 aaaaaggaat tccgactgat cttgaaacac tgacgaaaga gatacaggaa agagaccatt
    39721 atgattcaac aagggacgtc tctccgctga agcaagcaga ggatgctgtt cgtatcgata
    39781 cgactggcaa atcgattcca gaagtcgttg cagcaataaa agctgttgtt ttgaaaaaag
    39841 gttatcttct tttttaaatt aagaaaaaaa atgaaaaaca attgtttttt caaggaaaac
    39901 gaacgaaatc gctttatttt ttttgaataa tcaattaaac taaaaacagt accgtactta
    39961 cggcagaatg ttggttagga ggacaagtgt tatgacagaa tttgatcaaa atcaagagaa
    40021 caaccagtca atggaagacg caatgaaaag cgtacaagaa gtaaaagttg gcgatgttgt
    40081 taagggcgaa gttttagtca ttgaagacaa acaagtgatt gtcggaatcg aaggggctgg
    40141 agttgaagga gtcgttccgg caaaagaatt atcaactttg ccggtagaag atatcagcga
    40201 agtagtaaaa gtcggtgatg tattagattt agtcgttatc agtacgatcg gcaaagataa
    40261 agaaaacggc agctatctac tttcaaaacg ccgtttagat gctaaaaaag tttgggaaga
    40321 tatcgaaaga gatttccaag agggcaaggt catcgaagca cctgttacaa atgttgtcaa
    40381 aggcggttta gtcgttgacg tcggtgtacg tggttttgtc cctgcatcaa tggtggaaga
    40441 tcattttgtt gcagactttt cagactataa aggcaaaaca ttgagcttta aaatcatcga
    40501 aatcgaacca tcagaaaatc gtttgatctt atcgcataaa gcggtagtgg aaaacgaaag
    40561 agaagaaaag aaaaaagaaa ttctttcaac tatccatgag ggagatgttc tcagtggacg
    40621 tgttgcacgt cttactgatt ttggcgcatt tgtcgaccta ggcggaattg acggtctagt
    40681 ccatgtctca gagatttcac atagtcatgt agcaaaacca agtgatgtat tggctgtcaa
    40741 tgatgatgta aatgtcaaag tgttgtctat caatcctgaa caagaacgtg tttccttgtc
    40801 aatcaaagac acacagcctg gaccttggtc agaaatcgat acaaaagctc cagttggcac
    40861 agtattagac ggaacagtta aacgtttgac aagcttcggt gcctttgttg aagtgttccc
    40921 tggagtagaa gggctagtcc atatctctca aatttcacat aaacatattg cgacaccaca
    40981 tgaagtgctt catgaaggtg acgaagtgaa agtgaaagta ttagagatcc atccagaaga
    41041 acatcgtatt gcattgagta tcaaagcttt agaagaaaaa ccagcttcag aagaagaacc
    41101 aaaaaatgtt gagtcttatg aattaccaga agaaaatact ggatttacta tgggagacat
    41161 tttaggtgat gcgttgaaag aagaagtaga agaaaaagca accgatgatt ctgaaaaata
    41221 attgattttg tatctgtgac tgagatgaaa gcagctgctt ttgtctcagt ttttcttttg
    41281 aaaagcgatt agtatttcaa taaggaataa aaatacttcg tttaattgac aatctatgct
    41341 tgaaagttgg caatgcattc gttaaactaa gtgagattgg aaacttgtga ggaggaaata
    41401 atatggcaaa tccaacaatt gcaatcgttg gccgcccgaa cgtcggtaag tctacgattt
    41461 ttaaccgcat cgctggtgag cgtatctcga ttgtcgaaga tactcctgga gtaactcgtg
    41521 atcgtattta tgcaaaaggt gaatggttag gtcgagaatt cagcgtgatc gacacaggcg
    41581 gaattgatct tggcgatgaa ccttttatgg atcagatcaa gcatcaagca gaaatcgcga
    41641 ttgaagaagc agatgtaatc atttgtgtag tcagcggacg cgaaggcgtg acagacgcag
    41701 atgagatggt tgcgaaaatt ttatacagaa gtaataaacc agtgatttta gcagtcaata
    41761 aagtagataa tccagaaatg agaaacgata tctatgaatt ttattcctta gggctaggcg
    41821 atccttatcc tgtttcagga agccatggac tagggattgg tgatatttta gatgaagcag
    41881 tgaagtattt ctctgaagag actgaagaag aggacgacga cacgattaag tttagtttga
    41941 ttggtcgccc aaatgttggt aaatcctctt tgatcaatgc gattttagga gaagaacgtg
    42001 taattgtttc ggatattgaa ggaacgaccc gagacgcaat cgacacccac ttcgtttctg
    42061 aaagtggtca gaaattctta atgatagata cagctggtat gcgtaaacgc ggaaaagtat
    42121 acgaaaatac tgaaaaatac agcgtgatgc gtgcaatgcg tgccattgac cgttctgata
    42181 tcgttttgat ggtactgaat gctgaagaag ggattcggga acaagacaag cgagtagcgg
    42241 gttacgccca tgaagctggt cgtggaatta ttatcgtcgt gaataaatgg gatcttgtaa
    42301 agaaagaaac caatacaatg cgtgatttcg aacaagagat tcgtgatgaa ttccggtatc
    42361 ttgattacgc tccaatcgtt tttgtttctg cagtgactaa acaacggttg gaacgtctgc
    42421 ctgaaatgat cgaacaagta agtatgaacc agaatcttcg tatctcttcg gctgtgttga
    42481 atgatatcat tatggatgct gtagcaatca atccaacacc aacagataaa ggaaaacgcc
    42541 tgaagatttt ttatgctaca caagtcgctg tcaaaccacc tacatttgtc gtttttgtca
    42601 atgaagagga attgatgcat ttttcttatg aacgtttctt agaaaatcaa atcagaaaag
    42661 catttacttt tgaagggacg tccatccgaa ttatccctcg taggagaaaa taggcatttt
    42721 accatatcga cgtttttttt tcaaaagaaa aagacagttt cgtttgttac gtttctatga
    42781 ctaaaaaaag catgtgaaaa ttggtaaaaa ccttgctatt aagcggttca tatgatatcg
    42841 tgataacaga atattgaagt taatcaatat ttctttttaa acttctggac cactcagaaa
    42901 gttttaacta aatgatattt ctatcatatc tcttgtggag gaggtgaatc tatccatggc
    42961 aaacaaagca gaattaatcg aaaaagttgc ttcagctact gatttaacta aaaaagatgc
    43021 aactgcagca gtagatgctg tattttcaac tattcaagat gctttagcta acggcgaaaa
    43081 agttcaatta atcggttttg gtaactttga agttcgcgaa cgcgcagctc gcaaaggtcg
    43141 taacccacaa actggtgaag aaatcgaaat tccagctagc aaagtacctg cattcaaacc
    43201 aggtaaagca ttaaaagacg ctgttaaata agacagttga aaaagcgctt gtggctctag
    43261 ggctacaagt gcttttcttt ttatttccta gcagaaaagg aataaataag agacagagat
    43321 tccgaatccg tatgtcatac atagaaaaca catgtatttt atttaatttt tatttatttg
    43381 caagttatga ggtgagcttt gctcttatct tttctagaat ttgcttacta atggtaaaat
    43441 aaaaataaga agaggaggga tgcgtatgga acttgattat caagtagaag atgcgttgac
    43501 gaaagtgttt tacggagaaa cgctagtcag tcagctaaga gaactttcca ttgatcagcc
    43561 aatcttattt ttaacgaatc agcgctatta tgatttgttt gcagataaga tcaacccgtt
    43621 atttgcaaat caagcaaaca atgactggta tatttgtgcc aacactcaat gcaatcattt
    43681 aacagaatta aagaacctgc ttgatttcgt caaacgctat cccgaaaatc aatccatgtt
    43741 tatcatcgga tttggaaatg aagggatcat ggatctggca ggtttttttc aaaaacatac
    43801 aacccttgat tcatcactat ggatgatccc tgtatcgatc cgttctctaa gccgagcatt
    43861 aacaccgcag cggacgattt tgcagctacc aaatcgtgta gtgctgcaaa ccatcaatct
    43921 gccagaacgc atcgtttatg atcaaacaat cagcgagcgg caggtggacg gaaagcagat
    43981 tgactttttg acttttatct gttgcggaat gatttgtgat catcgttttt tgcaaaatct
    44041 gtataaaaac tatccaaata aaaagcaatt aacgactcgg ccgtttgccg ggatgatcga
    44101 agaaatgatc tatttttatc aattagaggc agaaaacctg tcaaattatg gtaaactgtt
    44161 tgaacaagct ttttatctga ccgaaaatgg ccatctactt tctgctagta tgaaaaaatt
    44221 tttaggaatg atgtttcatt tcgtgtggaa tctccaagca tatccttttg atttccaact
    44281 aaaaaacttt tttgtgtggc tggacttgct tggctatcca atccactggc tggaacagat
    44341 ttcaaagatg gagtatttgg aaaaagttct ttttttggca gaaaaaagca aaaaaatact
    44401 tgttttagaa aaaataggta taatagacgg ataccaacat ccaaacgaaa aagaattatt
    44461 gagaacaatg acggtatttc aacaaatcgt cagtgagata agagggaatt gaaatgaata
    44521 caaatagcga aaaaatgttg caagctttat cagatgaaga cttgtcacaa gcacaaatct
    44581 ttttagaaaa agcattaaaa gaagacccag cagatatatt agctgaacta ggcgaagaat
    44641 tgctggctat tggctttttg atcgaagcaa aacagatttt tgaacaactg atcaaccaat
    44701 acccagaaaa tgacggactg aacatcccgt tagcagaaat tgcaatcgaa gataatgaga
    44761 tcgacttagc ttttgaatac ctggaaaaag tggataagca aagtgattac tatccgcaaa
    44821 gcttattggc gatagctgat ttgtaccaag ttatcggaat ccctgaagtg agtgaagcaa
    44881 aattgaaaga agcagctggg ttgcttcctg atgaaccatt gatccagttt gcgctagctg
    44941 aattgtattt ttcagttgat cgtttcaaag aggcagcagt ggtttatgaa acattgttgg
    45001 caagcgggat aaatgaaatt tcaggaatct cgatgcagga acgtttagga caatccttaa
    45061 gtatgcaagg agaattcgaa gcagctatcg tacctttaga agaagcactg aaagaagaaa
    45121 ggacagatga tcgactgttc cagctagctt ttacgaatct tcaattgaaa gaaaatcagc
    45181 aggcaatcaa ctatctggaa gaacttcgag aagttaatcc gcattatcaa tcgttatatc
    45241 tatatctagg acaagctctt caagaagaag aaatgattga agaagcacaa acagtgttag
    45301 aagaaggaat caaagaaaat ccttaccaag tcgaacttta tcacctggcc tcggaaaatg
    45361 ctttccgtct gcatgataga cagcgagcag aagaactttt actgaaagct ttagaagtag
    45421 gagacaaaca agatgaaaca ttacttactt taagtaatct ttacttggat gatgaaagat
    45481 atgaagatgt gatacaagtg atcaatcaga tggaagaaac tgctaatcct tatgcagaat
    45541 ggaacctagc ccatgcttat aatgaattag aagactttac cgttgcagct gtacactatg
    45601 aacaggctta tcatgaacta tcacatgaac cagatttctt gaaagagtat gcctttttct
    45661 taagagaaga agggcagctg aaaagagcgc aagaattatt gacttattat ttaacacttg
    45721 aaccaggaga tatggaggca ctgtcattat tagatgacct aacagagagg tgagaaaaat
    45781 gctaattgat gtacgggaaa agaagaattt tttaacgtgg atggtcaatc atgtatcttt
    45841 tagccgaaga gaagtttttt ggatcttgaa ttatcttgcc aatcatgaag cgattttaag
    45901 caatgtccac tttgttgaag gggcgaattt tgcggatcga ggactgcaga tcagtgatct
    45961 atctgttgaa ggggaaccca tgaaattgtt tttgcaggga aaagaattta cggacacaga
    46021 ccagattttt catgaaatcc gtttgaattg gaaaaagcct ttatatgtgg aatgtatatt
    46081 cgaaaatgct tggcagacaa gagaatatct atctatctta gaagacaatc cattttcttc
    46141 ttgggattct tcagtcagtg aagaagatac tgaattaatt gaacgatatt ttcaagaaaa
    46201 agaagaagag gcaaaactaa aaatgcttta tgctcaaatc gatcaagcac tagaagatgg
    46261 agatagggat gcttttttga aattatctga tgaagttaac cgaaagatcc ttttgcagac
    46321 acaaaagaaa agtaaccggg taagtgaaca taacaattag ttaaaaatag tatagtacta
    46381 aaaaagacaa aggtcagctg gatgtggaat ctttcctcat agcctatctt tgtctttttt
    46441 cttatagttt tttcagtaat cttgtctgtg gcttcaaata agtaaagcct tgcccttcca
    46501 cttcatgcac attgatgatt gaaaggaaag ctttttcgtc aatctcgtgg acgatcctct
    46561 tagcttcagt taattcacta gagctaacga ccatatagat gatttttttt gaattaccag
    46621 agaatgcgcc ttctccagaa aggaaagtca cacctctttg cagaccggtc atcagtagtg
    46681 gtgcaatctc ttcgcttttg ttggagacga caagtagacc ttttgcagaa tatccgccat
    46741 ctaagatcga atcaatcaca cgactgaaaa catacgaaac aatcaacgta tacatcatac
    46801 gtttcaagtc gatataggtt aatgaagcaa gtaagacgat gatatcaaat gccaataggg
    46861 aacgccccat agtgatgccg taattttgtt ctaaaatccg agcgataata tcactgccgc
    46921 ctgttgttcc acccatgcgg tagacgatcc cgcttcctac acctgcaact aaacccgcaa
    46981 gtagagaaac gatcagtaga tcatgctgta aattgatttc tagtggaacc ctttgccaga
    47041 tccataaaaa gaatgacaaa gaaagtgtac ctagaacagt ataggccaag gaacgtttac
    47101 cgaggatctt tcctcctagt aaaatcaatg ggatgttgat taataaagtc gtataagctg
    47161 gatcaatacc aaataaagct cttaagatca aggtgatccc tgagactccc ccttctgcta
    47221 aatgattagc gatgttcaag taaacaagac caaatgcata aatacttgtt cctataatga
    47281 taaaaagaac ttcttttact gtttttcgtt tgaccatatg aattccagct ttcaattatg
    47341 tattttcaca gaatttccat ttagaaattc cttcctaaat gtagcatgga aattcgattt
    47401 tctcaattgc tcttatctag gatttgcgtt aaagttttgg taagatagtt ttggagggaa
    47461 aaagatggat aaaaagcgtt ctttatacag tatgcagcag gaagtggatg aatatatcca
    47521 gcaattcaag gtggggtatt tctctccatt agctcagatg gctcgattaa ctgaagaagt
    47581 aggtgaattg gcaagagaag tcaaccacac ttatggagaa aaaagcaaaa aggcttctga
    47641 accagttaac tcggtagcag aagaacttgg tgatgtttta ttcgttacga tgatcatggc
    47701 taattcattg aatatcgact taactgaagt ttttgaaaaa aacatggaaa aattcaatca
    47761 aagagaccat aatcgctttg agcgtaagga cgagtaaaca agatgaagtg gtcctggcct
    47821 tgaagactct gaaacggact tgtcaaacag tcaccatgca actgagtctt tatctcagga
    47881 caagaaacac gcaggaaagg ttggaaaaat gaaattaaaa caattacctc tggaatacca
    47941 aaaggcaatt ccagttctga aaaaattaga gaatgcagga tatgaagctt attttgtagg
    48001 tggaagtgtt cgtgatatct tgctgaacca gccaatccat gatgtggata tcgcaacaag
    48061 cgcatttcca gaagaaatca aacagctttt tccaaaaacg atagatattg ggatcgaaca
    48121 tggaactgtg ttggtattag aaaatgatga acaatatgag atcaccacat ttcggacgga
    48181 atcaacttat caggactacc gtagaccaga tcatgtcgaa ttcgttcgtt cgttggcaga
    48241 agatttgaaa agaagagatt ttacgatcaa tgcgtttgct ttgaaagaag atggagaaat
    48301 catcgatttg ttcgatggtc tgcaagatct agaagaacag atcttgcgag ctgtaggcaa
    48361 tcctcatgag cggttccatg aagatgcctt acgaatgatg cgcgggttgc gttttgtcag
    48421 tcaactaggg ttcaaattag aggaagaaac cttctacgcc atcaaagaaa accacgagct
    48481 attaggtaaa atatctgtag aacgtataaa tgtggaattc atcaagatgc tcttgggaaa
    48541 tgaacgggcc gcgggaatcc atgcatttat tgaaacagag tgctacattt gctgtcccgg
    48601 tttgaaagaa gaaggcgaag cacttttacg ttttgctgaa ttaccatccg tcccattgaa
    48661 agaagagagc caagcatggg cattattgat cagccaactg gatctaaaag aaaatgagat
    48721 tcgttccttt ttgaaatcgt ggaagtgttc taaccaaatg attaaagacg ttcaagcact
    48781 tgtccaagga ctacgacaac gagaaactgg agctttggaa ccattcgaat tgtacttctt
    48841 aggcaaaaaa catgcactgc aagtagaaga attgatgatc tattttgacg aaacacctca
    48901 gatggatgcc gtaggagaat cctatgatcg tttacctatc aagtcattaa gcgaattagc
    48961 agtagatggt aaaatcttgc tagaagaaac tggaaaaaaa cctggtaagt gggttagtga
    49021 agctttgcaa ttagctgaaa aagccgtcgt agaacaaaga ataaaaaatg ataaaaaaca
    49081 ggttttggat tttttatcga aagaaaaatt gatttaaaaa acactagact gtatctgctc
    49141 agctttgttg gctacttaaa gtgggcagat acgtcattag aagaaaaaac ataagatgtg
    49201 accacttaca taaatttgtg ctaaactgag gtagtacaag aataaattac atcataaagg
    49261 agtcttttta atgagtaaag aaatgacagc gctaaaattt tattttagaa atggagaaac
    49321 ctggacgatc aaccgccgtc atatcggcga tctttggatc aaacaaatca caacaagttt
    49381 tggacgaatc aatggcagtg aatttgttga aatccatccg tgtgctggat ttaaaatcga
    49441 aatcttccat gaaggggacg cagttgcgac acatgatatc aacctaggcg gactggaaat
    49501 gggcatgttt aatcgcgcat tgaaatacga agatatcgag cgaatggaaa tcctttaccg
    49561 aaatggcaca cctgatcttg tgtacttccc atatctagat aaaggaacag aaggattaga
    49621 caatcaatat caatcaacaa aaatcagcga aaaaacaggt aacttgtata tcgtgatcaa
    49681 tccagatcaa cgtgtagaag atgtatacgg ggaatttttc gaataaatcg atttttacgc
    49741 aaaaatgagg ctgtgaaaga gatgtgtctt attactactg ataggctgtc tcttccacac
    49801 cgtttattca gaataaggga ctgtgacaag atttttgtcg cagccccatt tttttgttgt
    49861 gataaaagaa caagaaaggc aggaatggga aagtaaacat ccttttgtca gaaactttta
    49921 tctttcttaa gttttacttg atatctgata ctatttggaa tagaatgagg cgttgaaaaa
    49981 tttatggaaa tttctaacta gcaataaacg atgaaacaat gaaatatttt tcatccaaaa
    50041 agaactttgc tataatgatg gaagtttgtg tataggagat ctggaaaatg agagagagtt
    50101 ttgaacaaca aaaaaaactg ttgcatgatc gctatggcgc cctttcgatg gatgaccgcc
    50161 gtcaaatact ttgtaagttg cgtaaaagaa atatattgat gtatcgtcag ttggaacgtc
    50221 tgaaacatga tctgcttcgt ttggagtcaa aacgtgtaca gtgtgaatta gaggggaacc
    50281 aaacacaggt tgaagtagtc gaaaccaaaa ttttaaagaa aaaagaacaa tttttaaaaa
    50341 tgcttacaca aaataaaaaa taaaggggat ggacgatgga atttgctgag ttagttattg
    50401 tatttgcagt aacgatcacc ttatcgaaca tagctagccg cattttgcca atgattccag
    50461 ctccactgat ccaaattttc cttggagtgg tattaggtct gacagagtgg ggacaatcaa
    50521 tcgattttga acctgaattg ttcttagtta tgattattgc accattgtta tttagagaag
    50581 gagaaaaagc agatatttct tcgattctca aaaatttcgg gacaattttg ttcttggcat
    50641 ttggaggagt cattttgacc cttgtcgggg taggtgcgac gttatcattc ctgttgccaa
    50701 gtgtcccact tgctgcctgc tttgcttttg gagcagcgtt aggtccgaca gatgcggtag
    50761 cagtcagttc tctttctgga cgagtgaata tccctaaaaa ggcgatgcat attttggaag
    50821 gagaaggtct tttgaatgat gcatctggtg ttactgcctt ccagtttgct cttggtgcgc
    50881 tgatcaccgg atctttttca gcagtaaacg cggggatgag tctagtagtt tctagtattg
    50941 ggggagcttt gatcggcttt ttgcttgtct ggttcaaaca aaaaataatt catttgatcg
    51001 aaaaagcatc agcacaagat gtcacagggt atctgctgat cgaacttttg cttccttttc
    51061 tagcctatgt attggcagag gcatttgatg tatctggaat cattgctgca gtggcagcag
    51121 gtattctcca agcttctggt tttaggaaaa tctctgtgtt tgatgcagaa ttgtcgagct
    51181 tgtcccacag tacatggaca actattgctt ttacactgaa tgcattagta tttatatttt
    51241 taggaatcga attgacgcaa gtgttctcgc cagtatgggg agacggttta tatccaaacg
    51301 gtcttttatt agcgattatc gtattaatct ctgtcatgct ttttgtgatc agattcattt
    51361 ctatcagtct tttttatgta ttcaaagatg gcagtaaaaa gttcaaaaaa cagttgaacg
    51421 agatcttgat cttaacattt ggcggtgtaa agggaacagt cagtttggct acgattttta
    51481 ttttgccatt ttcaatcaat aatatgatgt tttaccagcg gtctttgctt ttgtttctga
    51541 cggcgggtgt catcttagtg actttggtca tagggatcat tgtcttgcct atgctgacgg
    51601 aaacagagga agcgaaaagc acggatttga atgctttgat gattttagaa gaggtcgttg
    51661 aagttttgcg aaaagaaata aaggaaattg atcgtaatac aaaagaattt ttagccactg
    51721 aagcagtgat agaaaattat caagaacgga tacgtgatct gtacttggaa gatttaaccg
    51781 atgatgaaaa gcaagaagta caagaaatac aagcactgat tttgtcgatc gaacgggatg
    51841 gattggatga aagttatcgt tcgggcaagc tttcttctaa tggttatcgt ttttactccc
    51901 gttttctttc tcgattcgaa cattctatca caagccagat tttgtctttt atcggctttt
    51961 ggttcattgt tgtccgtagg ttaatgcgaa tcgttctcca tccgaaaatg ttttggcaaa
    52021 gaagatatgc tgatcgtcag acatttatta gtgatgaaga tatccaagaa atcagagaga
    52081 catatcaaaa aaatactcag ttgattattg aaagtttaga taacttgact gatatttatg
    52141 atgaaacgat ggttcaattt tttatccagc aacgcaaact tgaaggaata aaaatgaact
    52201 cggggaattt gatttcttcg tggatgatcc agcaagatag tctgtttacg aaaaaaatgc
    52261 taagaggtta ttatcttgaa agaaaaatca ttgatgaata cgaagttgct gaaaaaatca
    52321 cgacgttttc tgcgaacagc tatcgcagga atatcaattt gttagaatct tatacgatga
    52381 acaaaccatc tgataacttt tctttccgat ttgcgtttcg agcaaagtca aaaaaaacga
    52441 gtccaataaa ataaaaaggt aaaaattttc aagttttata aaaaacaaaa catatcagaa
    52501 caggatcgaa tcggtcctgt tctttttttg agaacacaaa aagaacaaat accaaaaaaa
    52561 ttttcctgaa gttcactatt tttatgatac aatatccaag ataaggaggg aacatgttga
    52621 aagaattaaa agtaactgac ctcaaaaaaa cttatggtga aaaagatttg tttgaccaga
    52681 tttctttttt ggtccacgaa aaagaccgta tcgggttgat tgggacgaac gggacgggta
    52741 aaacaagtct cttaaatatt attgccggta tcgatagcag cgacggtgat cggcaaacag
    52801 tgttttatcc aactgattac cgtattggtt atctttctca agcagctgaa ttttccgatg
    52861 aattaactgt tctccaagca gtctttcaag gaaacagccc cttgatccaa actgttcgag
    52921 catatgagga agcattgatc gaactagggg aaaacggaga agaccctgat gtgcaaaaac
    52981 gttatgctaa agcagaagaa caaatgaata aagaagatgc ttggactaca gataccaacg
    53041 caaagattat tttgcaaaaa ttaggaatca gtgaattaga taaaaaaatc agtactttat
    53101 caggtggtca gaaaaaacga gttagtctgg cgcaagtgtt gattgatgaa cccgatttac
    53161 tattactaga cgaaccaaca aaccatttag attatgaagc gatcgagtgg ttggaaaact
    53221 atttgaaaca ataccgtggc gcactattga tggttaccca cgatcgttat tttctagata
    53281 gagtagcaaa ccgaatcttc gaactttcat ttggaaaatt atacgagtat aaaggaaatt
    53341 atgaagctta cgtcttagaa aaagcagaac gtgatcgtgt agaagtagaa caagaagaaa
    53401 agcgcaagcg gctttataaa caggaattag cttggatgag ggctggcgta caggcacgtg
    53461 gcaccaagca gcaagcacgg atcaaccgtt tcgaagatct aaaggagaac ttgtaccaag
    53521 taaaccaaga agatgattta gagctgaacc tagcgacaca acgtttaggg aaaaaagtac
    53581 tggaaatcaa agatggcagt taccgtataa atgaccaaac actgctagaa catttagatt
    53641 tattgattca atctcgggaa agactaggta ttactggtaa aaatggtgcg ggaaaatcga
    53701 cattgcttaa tattctagct ggcagaattc ccctggatag cggtacaatg tctatcggtg
    53761 aaacggttca tcttgcgtat tatacacaag aaaatgaaga aatggcacca gataaacgga
    53821 tgattgctta cttacaagaa gctgctgaag aagcaaaaac agcagatggc agtcaaatcg
    53881 gagtagcaga attacttgaa cgatttttat ttccaagatt tatgcatggg acactgatag
    53941 gcaaactttc aggcggagaa aaacgccggt tatttttgtt gaaactgctg attcagcaac
    54001 ctaatgtttt attattggat gaaccgacca atgatttgga catagcaaca ttgacgattt
    54061 tggaagatta ttttagaagt tttccaggtg ctgtgatcac tgtttcccat gaccgttatt
    54121 tcttggacaa ggtagcagat aagttattag tattccaagg aaacggaaaa caagaacttt
    54181 attacggaaa catgtccagt tatttactga agcaaaaaga gacccagcag cctgctgaaa
    54241 aagcgaaacc aaaaatacag agcaaggaac ctgctgaaaa gaagaaatta tcttacatgg
    54301 aacaaaaaga atgggaaacg attgaagatg agattgcaga acttgaagaa aaaatctcat
    54361 tgctccaaga agagatgaat catcaaggag ataatttcac tcgattacaa gaattgcaaa
    54421 acgacgtatc tgaaacagaa gcacaacttg aagaaaaaat ggcacggtgg gaatacttga
    54481 gtgaatgggt agaagattag gaggaaaaag gatggaacaa gcgtatcttg acttaggaag
    54541 aaaattgttg gaagaagggc atcgtaaaga agacagaaca ggcacaggca cattaagctt
    54601 attcggatac caaatgcggt ttgatctgca aaaagggttt cctttgttaa caacgaaacg
    54661 agtacctttt ggattgatca aaagcgaatt gctttggttt ttaaaaggag atacgaatat
    54721 ccgctatcta ttacaaaata aaaaccatat ttgggatgaa tgggcatttg aacgctacat
    54781 caaaagtcca gactataatg gaccagatat gactgatttt ggccatagat gtttgacaga
    54841 tcctgaattc aatgaagaat ataaaaagca gagcaagctt ttttgcgaga agatcctaac
    54901 cgatgattcc tttgctgaaa catacggcga tcttggacac atctacggct atcaatggcg
    54961 tcactgggaa acaaaagacg gtggctttat cgatcaaatc aaacaagtga tcgaagcaat
    55021 caaaaagact cctgattcta gaagattgat cgtttctgca tggaatccgg aagatgttcc
    55081 tagcatggct ttgcctcctt gtcatacgat gtttcaattt tatgttcaag agggacggct
    55141 aagctgccaa ttgtatcaac gcagtgggga tgtgtttcta ggcgttccgt tcaacattgc
    55201 aagttatgcg ttgctgactc acctaattgc acatgaaaca ggtttagcgg ttggcgaatt
    55261 tgttcacaca ttaggagatg ctcatcttta tatcaatcat atcgaacaaa tgaaagaaca
    55321 attgagccga gaaatacgcg catttccgac tttagttttg aatcaggaaa agcagtcagt
    55381 atttgatttt gagatggaag atatccaatt agaaggatat gacccacatc cggcgatcaa
    55441 agctcctatc gctgtttaga atcagaaagg atgagaaaat gttagctgca atttgggcac
    55501 aggatgaaaa cggattgatt ggaaaagaag accgtcttcc ttggcgtttg ccaaatgatc
    55561 tgaaattctt caaacaaatg acagaagcaa atacactagt gatgggacga aaaacattcg
    55621 aagggatggg tagccgtccg ttgccgaatc gtcagacgat tgttttgacg agagattctt
    55681 cctataaagc agaaggcgtg catgtcatgc atagtgtgga agacgtgctt gctctggaaa
    55741 aagaaacaga cggtatcttt ttcatcgctg gagggtcagc tgtttatcaa gaatttctgc
    55801 cattttgtac gatattatac cgtacagtca tccatcatgt attcgatgga gatgcttatt
    55861 ttccacctgt tgactggtct gattggtcac tgatcaatac tagtcaagga gaaatggatg
    55921 aaaaaaatcg ttatccgcat caatttgaaa cgtatcagcg taatgagaat cctgtaaaaa
    55981 gcgggacagg cgaattgacg atataaaaaa gctatggata gactagctgt tatttagagc
    56041 tgtcccatcc atagctttat tttttttatt aagtaaagaa taaaacagag aagtacataa
    56101 aacctgcacc taacataaca aacaaatgcc aaacaacatg catatagcgg atagaattca
    56161 agctataaaa gaatgcgcct atcgtgtaag aaagcccgcc tgctaccatc aaaataacac
    56221 cagtcattcc aagagagtga taaagaggaa cagcagccac gacacagagc caccccataa
    56281 aaatatagat gatcgtagat acttttgata ctctctcccg tttatgcaac gtcaacgctt
    56341 tatatataat gccaagaatc gcaaacaacc agattaatac aaataaagtc caacctagcc
    56401 atcctcggat actcagcaaa caaaaaggag tataacttcc tgcaatcaaa agaaaaatcg
    56461 aactatgatc gaatacttgg aacacctttt ttgcttttgt aaaaatcaat gaatgaaaca
    56521 aagtagacgt taaaaataaa agaatcatca tcgatccata gatagcataa gagacaatat
    56581 ggagggagga atgcaagtgg gcacctttta ctaaaagaac cactagtccc gcgatactca
    56641 atccagtccc aattccatgg gtgactgcat taaacacttc atttaatatt tcatacgttc
    56701 gattaaattt cgttttttcc atgaaaacgg ctcctttact aggtgtaatt aatgaaaaat
    56761 cattatttgt ctgttatact aaaaatagaa attgtcttac atgtagttta acatgaataa
    56821 ggcatcttgt taaagaaaga gagagagaaa ataatgacaa atgtaaaaat cgtaacagat
    56881 tcttcatgta cgatggaaaa aaatgtacgc gatgctttag gcattcgtgt catgccgcta
    56941 tccatcatga tcgacggaac agtatatccc gatgatgacc aactagacgg cgaaagattt
    57001 atggaaatga tggcgaaagc aaaaaatctg cccaaaacaa gccaaccacc aattggagaa
    57061 ttcatctcga tgtatgatga gctaggagaa gacggcagtg aagtgatttc gatccatatg
    57121 acaaaaggct tgagtggaac agtagaagca gcaagacaag ccagtaatct aacaaaaacg
    57181 aaagtaacgg ttatcgacag tgataccact gaccaaggat tatcttttca ggtaattcga
    57241 gcagctgaat tagcaaaaga aggtaaaaca gtagagaaaa tccttgaaga agtcaaaaaa
    57301 gtacaagaca atacaaaatt atacatcgga atatccacac tagataactt ggtaaaaggt
    57361 ggaagaatca gccgaacaac tggtttgctg tctagtgttt tgaacatacg cgtggtgatg
    57421 aatttcgccc attctgaatt aatccctgta actaaggggc gaggaaagaa aacgttcgat
    57481 aaatggttta ataatttgaa aaatgaactg aaagaattgc caaatgtgcg acaaatcggt
    57541 atttcacatg cggatgcaaa agaattggcg caagaattca aagagggttt gcaagaatta
    57601 ttcccggaca tgcatatccc tgtactgcat acgaatccgg ttatcgctac gcatactggt
    57661 aaagacgcgt ttgcaatcat gtattatgta gattagtcga aaagaggata agccctcagc
    57721 ctgaaaggct tgcagcttat tctctttttc tttataaaat taggaaaata attgttttct
    57781 tttttcataa agactacctt tttgataaaa tttttgataa cattagaacc aatcgaatac
    57841 aagaggtgaa aaaatgaaat taacgaaacg acatttgatc ctcgttttgt tcccattatt
    57901 aattgcgatc atcatctatg caggtttagc tgcttctata ccgaaagctg gcccactaat
    57961 gaaaccagta actactgtga gagaagatcc aaataaaaaa gaaaaacttc actacatagc
    58021 tatcggagat tcgctgactg aaggagtagg agatcaaacc aagcaaggag gattcgttcc
    58081 ccttgtcgca aatgatctaa aagaccgtta taatttgacc gcggttgaaa cagaaaacta
    58141 tggtgtaaat ggtgaacgaa gtgaccagat cttaaagcga gtaaaaacaa aagaagaaat
    58201 tcgaaacaat atcaaaacag ctgattttat cacactgact gttggcggta atgatttgat
    58261 gaaagttatc caaaataatt tattcgggtt aacggtcaat tcctttaaaa agccactgaa
    58321 aaactatcag gaaaatgtca cagaactatt ggaagaattt cgatccctca ataaaaccgc
    58381 acctatttac attttaggca tctacaatcc attttatttg aactttcctg agatcactga
    58441 catgcagaca attgttaaca attggaacaa aggaacagaa acggtgacaa aaaaaatgcc
    58501 gaactgctac tttatcccaa tcaatgattt gctttatcaa ggattgaatc aggaagtagg
    58561 tgtcacagaa gaaggaacag atcaaacaac tagcacgaca gaaaatctaa atggcatcaa
    58621 aaataatgtg ctctatgaag aagatcattt ccatccaaat aatttaggtt atcaattgat
    58681 ggcaaatgca gtgagagatc agctgatcga gacacaaaac caatggttag agaaggagga
    58741 tgatcaataa acatgaaaac aagatctgac gtatcttcaa acaaaacaaa gaaaacaaat
    58801 tactggaaat tcgccttcct tatccttctt ggggtagtac ttggttcgac cgtattttta
    58861 ggcagccgta tttttgctaa tcgggaacca gaactcccag aaataccagc tcttacggaa
    58921 agacaaggag atcctgtctt aacgatcaat tcaaataaag aaaaagtcaa tcaaatcatc
    58981 agctttttcc ttagtgagta tcaaaaagat agtgatattg aatataaatt ttatttggaa
    59041 aatgaagcac tactcaatgg tactttcgaa gtactaggtt ttcctatcga tttctattta
    59101 tattttgatc cgtatgtgat ggaaaacgga aatgtccaac taaaagctag aagtctttct
    59161 atcggaacat tgagtttgcc aatcaaagat gtgatgaata tgatcaagag aaactataaa
    59221 ttaccagatt ggatcgaagt caatacagat gatctgacta tcatgcttag gttggatcaa
    59281 ttccgaatgc aaaacgggat gtatattaaa gcagataaaa tcgacttagt aaatgatgac
    59341 attcggttta gtctatattt gccaaaagat acctctgatg cttcaaacaa ctcaaatacc
    59401 aacaaaacta gcaccagcag tactgaaagc aagacaaaag aaaataaaaa atcatcggat
    59461 gagtagtatt agagggggaa tcataatgga acgagcaata tttgcaggag gctgcttctg
    59521 gtgtatgatc cagcctttcg acacgcttcc tggtatccat acagtgatgt caggatatac
    59581 tggagggcat gtaccagatc cgacttatga acaagtaaaa agccaaacga ctggacatac
    59641 agaagcagtg gagattatct atgatccaac attgatttca tatgaacaat tagtagaact
    59701 ttactggcag caaactgatc caactgacgc tttcggacaa ttcgaggatc gcggtgacaa
    59761 ttatcgcccg gtgatctttt atttgacaga agaacagcgg atcattgctg aaaaaagtaa
    59821 gaaacagtta gctgaaagtg gacgtttcga acagccaatc gttacaaaaa tcgaaccagc
    59881 ccaaccattt tatctagcag aagaagacca tcaagagtat tataaaaagc atcctgaaaa
    59941 ttttaaaaga aaccatgcac gccgggctgc ctttatcgaa gaaaattgga ggaacgaagg
    60001 gtgaatcgaa gcttttttca ttatttaatg acactgcgag gcggtggcac acatgatgct
    60061 ttatctgttt tcgctacaga agccggtaaa gacatccaat ttcctaagca cagctctagc
    60121 tacgaagaaa tttctaatta tctggaactg aatgtcgact atttgccgtc catggatatc
    60181 tttgacgaag catgggaaaa atatttagaa aataatcatg acatataaga gatagttttg
    60241 tactttatga tcaaaaaagt tttttgtcca atagcctaat tgaaagaatt atttttattt
    60301 cagctatcta gtcgcatttt tttgatattt ttcttataat aaagaaagaa tgaaaaaaag
    60361 agggatggat tgatagagat tgacaaaaaa acaacgctat attaatcgct tctggcttgt
    60421 attcaaatac ttacttgttt ctgtattcct tgcgttcatg ttgcggggat ttttattcat
    60481 cccggtacca gtggaaggca attcaatgga aaacgtgttg aagcaaggtg atatggttgt
    60541 gatggaaaaa ttttcggaga tcagacgatt tgatattgtt gtttttcaat tagcagatgg
    60601 cacgatttat atcaaacgag taatcggtct tccaggagaa aatgtcagct accaaaatga
    60661 tcaattgaag atcaatggga aagtagttaa ggaaccttat ctaactaaaa acctgaaatc
    60721 agatcatgca aatgcatcct atacgacgga ctttacacta caagagctaa cgggacaatc
    60781 caagcttccg gaagataatt attttgtact tggagataat cgaagagttt caaaagatag
    60841 tcgttcgttt ggcacgatca ataaaactga tattctaggt aaagcaagat ttgtctatta
    60901 tccacttgat gaaataaaat ggatccagtg agaaacaata aagcgtgcag tctgttgaga
    60961 ctgcacgctt tattgtttaa tccaaaatca gtttactacc ttagtacgta aaatcaaaca
    61021 gctcgtttaa acacttttct agcctctaaa gttttgataa atgaataaac aaccattatt
    61081 tgaataggga tttggatcat attcctgatg aatctaccta gaaaaattac tttgaaatct
    61141 gcaccaaaca aaacagacat cagccaagaa ttgataaaaa ggctgactgg gatcataatc
    61201 aataattggg cagcgatgac ggaaggcagg tttatctttt tatgatataa aaataagcca
    61261 ttaataaatc caccaaggaa agccgtgata agaaaagcag cttgaaacgt tcctgaacca
    61321 aatatcgtga aatttaaagt gttcgacaac atttcaagca aaccagccca gatcggtcca
    61381 tatagataac ccataagcgc catacttaaa aatccgaatg tgatttgaaa ataagcagga
    61441 ccaatcgcta tcttgtataa gatgacatca agggctaata aaagagcaga ggtcgacaac
    61501 aatcttgcat tcatttcggg caatctaaaa acgtcttttg caatcaaagt gttcaaaata
    61561 ttctctcctt tgtcagttaa taataaaagg ataccataaa atcaccaatg tgtcatgaca
    61621 cattggtgat ttacatacac tggcatctaa caattaaaaa aagggtgaga agactgcttt
    61681 tataaactgt aaaaaagaga ttgtacgaat aaaaaaaata gaggcggaga atacttatcg
    61741 tatcatccgc ctttgttttt ttgttataaa aaacgtcaga ttagttatct gcttacatct
    61801 tcatccatac gggttctaat gtatttccgt ctagatcttg gacttctaat gaaaacattt
    61861 cttcttcagg cattcccata tctacttcgt ggaaagtacc accattttct tttgcaattt
    61921 gagcaaattt ttttacttca tccgcatttt caacactaaa cgaaatcaaa gcaccacttg
    61981 tttttttatt atcagctatt tctttatctt ttataaattt tttataaaaa tcatgagaga
    62041 gaagcattat ccaaaaagtg tcatcccata ccattgaacc agcttcttca gtagaaaatt
    62101 cttcattttt tttaaaaccc agcttttcat aaaa
//
LOCUS       DAXLPC010000005        52237 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.005, whole genome shotgun sequence.
ACCESSION   DAXLPC010000005 DAXLPC010000000
VERSION     DAXLPC010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52237
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.005"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(34..870)
                     /gene="pheA"
                     /locus_tag="ACF3UE_000326"
     CDS             complement(34..870)
                     /gene="pheA"
                     /locus_tag="ACF3UE_000326"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFD3633787.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(867..1376)
                     /locus_tag="ACF3UE_000327"
     CDS             complement(867..1376)
                     /locus_tag="ACF3UE_000327"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFD3633788.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(1369..2664)
                     /gene="aroA"
                     /locus_tag="ACF3UE_000328"
     CDS             complement(1369..2664)
                     /gene="aroA"
                     /locus_tag="ACF3UE_000328"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFD3633789.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREIGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(2677..3768)
                     /locus_tag="ACF3UE_000329"
     CDS             complement(2677..3768)
                     /locus_tag="ACF3UE_000329"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFD3633790.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(3785..4951)
                     /gene="aroC"
                     /locus_tag="ACF3UE_000330"
     CDS             complement(3785..4951)
                     /gene="aroC"
                     /locus_tag="ACF3UE_000330"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFD3633791.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(4953..6017)
                     /gene="aroB"
                     /locus_tag="ACF3UE_000331"
     CDS             complement(4953..6017)
                     /gene="aroB"
                     /locus_tag="ACF3UE_000331"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFD3633792.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(6050..7072)
                     /gene="aroF"
                     /locus_tag="ACF3UE_000332"
     CDS             complement(6050..7072)
                     /gene="aroF"
                     /locus_tag="ACF3UE_000332"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFD3633793.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(7731..8705)
                     /locus_tag="ACF3UE_000333"
     CDS             complement(7731..8705)
                     /locus_tag="ACF3UE_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFD3633794.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(8686..10569)
                     /locus_tag="ACF3UE_000334"
     CDS             complement(8686..10569)
                     /locus_tag="ACF3UE_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HFD3633795.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(10587..12812)
                     /locus_tag="ACF3UE_000335"
     CDS             complement(10587..12812)
                     /locus_tag="ACF3UE_000335"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFD3633796.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            12927..13961
                     /locus_tag="ACF3UE_000336"
     CDS             12927..13961
                     /locus_tag="ACF3UE_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3633797.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(14028..15041)
                     /locus_tag="ACF3UE_000337"
     CDS             complement(14028..15041)
                     /locus_tag="ACF3UE_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3633798.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKHLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(15119..15307)
                     /locus_tag="ACF3UE_000338"
     CDS             complement(15119..15307)
                     /locus_tag="ACF3UE_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFD3633799.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(15747..15875)
                     /locus_tag="ACF3UE_000339"
     CDS             complement(15747..15875)
                     /locus_tag="ACF3UE_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFD3633800.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(15878..17251)
                     /gene="rlmD"
                     /locus_tag="ACF3UE_000340"
     CDS             complement(15878..17251)
                     /gene="rlmD"
                     /locus_tag="ACF3UE_000340"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFD3633801.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(17362..18417)
                     /locus_tag="ACF3UE_000341"
     CDS             complement(17362..18417)
                     /locus_tag="ACF3UE_000341"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFD3633802.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHADDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(18427..19857)
                     /gene="gatB"
                     /locus_tag="ACF3UE_000342"
     CDS             complement(18427..19857)
                     /gene="gatB"
                     /locus_tag="ACF3UE_000342"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFD3633803.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(19854..21326)
                     /gene="gatA"
                     /locus_tag="ACF3UE_000343"
     CDS             complement(19854..21326)
                     /gene="gatA"
                     /locus_tag="ACF3UE_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFD3633804.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(21326..21631)
                     /gene="gatC"
                     /locus_tag="ACF3UE_000344"
     CDS             complement(21326..21631)
                     /gene="gatC"
                     /locus_tag="ACF3UE_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFD3633805.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(21737..23773)
                     /gene="ligA"
                     /locus_tag="ACF3UE_000345"
     CDS             complement(21737..23773)
                     /gene="ligA"
                     /locus_tag="ACF3UE_000345"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFD3633806.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(23790..26024)
                     /gene="pcrA"
                     /locus_tag="ACF3UE_000346"
     CDS             complement(23790..26024)
                     /gene="pcrA"
                     /locus_tag="ACF3UE_000346"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFD3633807.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            26179..27738
                     /locus_tag="ACF3UE_000347"
     CDS             26179..27738
                     /locus_tag="ACF3UE_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFD3633808.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(27848..29779)
                     /locus_tag="ACF3UE_000348"
     CDS             complement(27848..29779)
                     /locus_tag="ACF3UE_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFD3633809.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(29797..30711)
                     /gene="pfkB"
                     /locus_tag="ACF3UE_000349"
     CDS             complement(29797..30711)
                     /gene="pfkB"
                     /locus_tag="ACF3UE_000349"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFD3633810.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(30708..31460)
                     /locus_tag="ACF3UE_000350"
     CDS             complement(30708..31460)
                     /locus_tag="ACF3UE_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3633811.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(31621..31830)
                     /locus_tag="ACF3UE_000351"
     CDS             complement(31621..31830)
                     /locus_tag="ACF3UE_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633812.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(31841..33169)
                     /locus_tag="ACF3UE_000352"
     CDS             complement(31841..33169)
                     /locus_tag="ACF3UE_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633813.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            33305..33460
                     /locus_tag="ACF3UE_000353"
     CDS             33305..33460
                     /locus_tag="ACF3UE_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFD3633814.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(33534..34121)
                     /gene="yihA"
                     /locus_tag="ACF3UE_000354"
     CDS             complement(33534..34121)
                     /gene="yihA"
                     /locus_tag="ACF3UE_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFD3633815.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(34204..35454)
                     /gene="clpX"
                     /locus_tag="ACF3UE_000355"
     CDS             complement(34204..35454)
                     /gene="clpX"
                     /locus_tag="ACF3UE_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFD3633816.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(35701..36990)
                     /gene="tig"
                     /locus_tag="ACF3UE_000356"
     CDS             complement(35701..36990)
                     /gene="tig"
                     /locus_tag="ACF3UE_000356"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFD3633817.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(37144..38076)
                     /locus_tag="ACF3UE_000357"
     CDS             complement(37144..38076)
                     /locus_tag="ACF3UE_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633818.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(38233..38892)
                     /locus_tag="ACF3UE_000358"
     CDS             complement(38233..38892)
                     /locus_tag="ACF3UE_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFD3633819.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(38895..39920)
                     /gene="sppA"
                     /locus_tag="ACF3UE_000359"
     CDS             complement(38895..39920)
                     /gene="sppA"
                     /locus_tag="ACF3UE_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFD3633820.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(39933..40223)
                     /locus_tag="ACF3UE_000360"
     CDS             complement(39933..40223)
                     /locus_tag="ACF3UE_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633821.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            40632..42437
                     /gene="glmS"
                     /locus_tag="ACF3UE_000361"
     CDS             40632..42437
                     /gene="glmS"
                     /locus_tag="ACF3UE_000361"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFD3633822.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(42509..43864)
                     /gene="glmM"
                     /locus_tag="ACF3UE_000362"
     CDS             complement(42509..43864)
                     /gene="glmM"
                     /locus_tag="ACF3UE_000362"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFD3633823.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(43888..45057)
                     /locus_tag="ACF3UE_000363"
     CDS             complement(43888..45057)
                     /locus_tag="ACF3UE_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFD3633824.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(45054..45941)
                     /gene="cdaA"
                     /locus_tag="ACF3UE_000364"
     CDS             complement(45054..45941)
                     /gene="cdaA"
                     /locus_tag="ACF3UE_000364"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFD3633825.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(46130..49822)
                     /gene="nifJ"
                     /locus_tag="ACF3UE_000365"
     CDS             complement(46130..49822)
                     /gene="nifJ"
                     /locus_tag="ACF3UE_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFD3633826.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLHHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLNLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            50021..50542
                     /locus_tag="ACF3UE_000366"
     CDS             50021..50542
                     /locus_tag="ACF3UE_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFD3633827.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(51241..51798)
                     /locus_tag="ACF3UE_000367"
     CDS             complement(51241..51798)
                     /locus_tag="ACF3UE_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633828.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(51977..>52237)
                     /locus_tag="ACF3UE_000368"
     CDS             complement(51977..>52237)
                     /locus_tag="ACF3UE_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633829.1"
                     /translation="DLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDFI
                     LGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
BASE COUNT        14124 a        11385 c         9406 g        17322 t
ORIGIN      
        1 taagttaaat aaatcaatca gtattcttga ctttcatcta cgcgtctctt ctactgtcag
       61 cactggataa cagcccaata tttgactttc tcctccgagc atcttgattt cttggagcgc
      121 attctctact aatgtcattg gacggtccaa caacaaatcg atcacgaaaa aatattctcc
      181 caagctagtt ttcaatggtc gggattcaat cttacttaag ttgatttccc gccagccaaa
      241 agctgccagc attttatgaa gcatccctgg ccgattagca ggtagtgtca agatgacact
      301 catttttact ggagctgact gctggctggt catctttcgg tcaccgacga tccaaaaacg
      361 tgtctggttc aactcattat cttggatatt ctcagctaag atctccaatc caacatgctg
      421 tgctgtttct aatgaagcaa tcgctgctgc gtcttctttc ggatgttctg ctacatacat
      481 tgctgcagca gttgttgatt ctgttgctac taaaggaaca ttaggataat gcgtttctaa
      541 aaactgttgt gattgtgcta gtgcttgtgg atgtgaaagg atttttgtaa tctttgttgc
      601 tggattgcct aaaagctgct gcttgatagg aagaacgatt tcacttttaa cttcgacttc
      661 tggatgtttg gaaagaagat cgattgtgtg atgaacagct ccttccaatg aattctctac
      721 aggaacgaca gccagatcga cttgtttgcg aaacaaagcg cgcaaacaaa cagggatgga
      781 agcatacgca gtcaattgtt ctgtaggaaa tagctgacaa gccgcctgat aagtgaatga
      841 actttctggc cctagatagc tgacgttcat atgcttttga tcctttctat aatggtatcg
      901 atgatctttt ctggtgtttg attggtcgtg ttgattcgat gtgtcgcact ttcttcatac
      961 caagaaagtc gttgtgccaa taatgctttt atttcttctc ttgtttttcc aagagctaaa
     1021 ggtcgaatag acgtttcatc ttgttggata cgatcaacta gacagtccgc ttctgcctct
     1081 aagtaaagaa caatcggctg tgtttttaaa aaacgccgat tttctgcact ttggacaatc
     1141 cctccaccag tcgcgataat tttgtcttca tttgacagct ttcttaaaat atctgactcc
     1201 acttttcgaa agcttttttc accgtaatag tgaaaatatt cggcaatcga caattggata
     1261 tgttcctcaa tctttgtatc taaatctaca tactcttttt gtaaacattg agctaaccct
     1321 ttaccgattg ttgtttttcc agcgcccatg aaaccaatca gcaaaatgct agccatgagc
     1381 ttctcctcct gacacaagtt ctgctaaatc gtcaaaaaat gccggataag agattgaaac
     1441 agcttcagct ccttctagtt cgcaaggtcc atcagctatc aaagcagcta cttgcagcat
     1501 cataccgatt cgatgatcgc ctctgctgga cacttttgcg ccatgcagag gtgtcggccc
     1561 atggatgatc agaccgtctg ctgtcgcttt tatctttgct cccattttct gtaattcttc
     1621 tgccaccgca tcaattctgt tggtttcttt tacttttaat tcttctgcgt ctttgatgat
     1681 cgtgattcct tctgcttgag tagccactaa agctagaatg ggcaattcat caatcagacg
     1741 cggaatgatt tctccaccaa tcgttgcttt cttcaaatga ctcgtcttga cacttaaatc
     1801 agccgattgg ttctgttcat tgtgattcgt ctgggtaatc gctgcgccca tctcctccaa
     1861 cacatctaag ataccagttc ttgttggatt gaccccgaca ttttttaaca acagttggct
     1921 ttccggaaca agaagtcctg ctgctagaaa gaaagcagct gatgaaatat cacctggaac
     1981 agttatctgt tgaccagtta atttttgcgg tccggtcact atgatcgttt tatcttccac
     2041 tgtgatcctt ccgccaaatt gacgaatcat ttcttccgta tggttacggg aacgttcttt
     2101 ttcaacgatt acggatgtgc cttctgcttg taatgccgca aacagcaaag cagatttgac
     2161 ttgcgcactg gctacaggca tattgtatcg gataggtgat aaagagcggg ttcctgtcac
     2221 agtgattggt agatactggt cattttcttc tccttgcaag tcagcgccga tctcgcgtaa
     2281 aggttccatc actcgcccca ttggacgttt agacaacgaa gcatccccga acagagtagt
     2341 cgtaaaaggc tgtccagcca aaatacccat caataaacgt atggtcgtac cggagtttcc
     2401 catgtcaatt gattcggttg gttggacaaa tgagtggcta ccgcgaccat gaatcttgat
     2461 cacctcttcc tcttcttcga tctcgacacc taattgttgg aaggcatgta aagtactcag
     2521 acaatcttct gcgcgcaaaa aattttgtat agtcgtcgtt ccttcagcaa ttgctccaaa
     2581 catgatgctg cgatgggaaa ttgatttatc tgctggtatc ctaacagtcc ctcttaatcc
     2641 atgtatttgt tgtaataatt gcatttatcc agcctcctat ttgatccagc aatgataact
     2701 ggtattagac ataatgattc tttttgcttg taacaaatcc tgttggtttt taaaactgat
     2761 ttgcagtatt cctaaaatat cttccctggt ctcttggatc ttcaaattaa tcaaagaaac
     2821 tcccgctttt ccgatcagtc cagttacttc tgcaataacg ccaggttcat ctggcacatc
     2881 gataaataaa tcaaaaaagg caggaatcgc gccttgctta tggacaggca actggtctcg
     2941 actttctttt gcccgattga aaaaagaaaa gatttccgat tggttctcag tcatgatcca
     3001 ttctgctatt tgtgtcattt cttgttgcca atctgccaat cgttccaata atatctgctt
     3061 attgctcaac aaaatatctg tccacatgac aggatctgag gaagcgatcc tagtgatatc
     3121 tcgaaagcct cctgctgcca gttgtttggc tcgcggatac tcttgattga attgttctgc
     3181 ctgattgact aagccagctg ccagaatatg tggaaaatga cttagcattc ctgttatacg
     3241 gtcatgttct cttgctgtaa gagttacata ttttgctttg gttccgcaaa atagttcttg
     3301 cagtttttca acatcttttt tcgtcttttc caaaggtgta aagatgtaat aggcattttc
     3361 aaatagttta gcatctgctg cctgtatacc tgatttatga gaaccagcca ttggatgtcc
     3421 accgacaaac cgaagatttt tctgctcagc ggatgtcacg acttgctgct tcgtactgct
     3481 gacatccgta atgatgacgt gatcagacaa gttgattctt tcaaggacat caagataagc
     3541 taaggttgta cggacgggaa cggctaataa gataacgtct gcttgttctg cacctgtttc
     3601 aaaatcactt gcaacgtaat caacgatctg ctgttctact gcttgctcac gggtttttga
     3661 ctgactatcc caaccaacta ctatcagttc tggattggtc tgacgaatac aaagtgccat
     3721 agaagcacca atcagtccaa gccccacgat aaaaacatgt tgtgccatct tatttgcccc
     3781 ctttttagta atgtttcaag tagtcacggt actccttcac tgcagctttc aactcaacaa
     3841 gcgaatcact tgggaatttt gacaatagct ctgtcgctac cacagtggct acaacatttt
     3901 ccgcaacgac gctagctgca ggaactgctg tactatccga acgttctaca cttgctttgt
     3961 aaggttcttt tgtatcgata tcaacacttt gaagtggctt gtacaatgta ggaatgggtt
     4021 tcatgacccc gcgaatgaca agtggttcgc cattggtcat tccgccttcg aagccgccta
     4081 gattattggt acgtcggaaa tagcctcttt cttcttccca taggatctca tccatcactt
     4141 ctgagcctgg taatgaacca gaagtgaatc cgaccccaaa ttctacgcct ttaaaggcat
     4201 tgatactaac cacagcttgt gcgattttgg catctagctt cgtgtcccat tgtacgtagc
     4261 ttcctaatcc agctggaacg cctccaacga gcacttctac aattcctccg atcgtatctc
     4321 catttttctt tgtctgatcg atcaaatctt ttattctttg ctcaactgct ggatcaacaa
     4381 ctcgtacttc tgacgcttca gaaatttctt tgatttcttg aatcgagata tttccaggta
     4441 tttctgcttg gattccacca agacaaatca cgtgtcctgc tacgatgatg tcaagttctt
     4501 ccagaatttt cttggcaatt gcgccgattg ctacacgcat ggtcgtctct cttgcagagg
     4561 accgttcaag cacattccga agatctcgat gatggtattt cataccgcct accaaatccg
     4621 cgtgtcctgg acgcggacgt gcaactcgcc gcagtgattg gtctttttca ggcacttctg
     4681 ctacagacat gacagttgtc caatttttcc aatctttatt ttctaccact aaagtgacag
     4741 gtgaaccaat tgttttgccg tgacggatgc cagacgtgat ccgaacacga tctttttcga
     4801 tcttcatcct tcctcctctg ccgtaaccag cttgtctgcg agcgagttcg tgattgattt
     4861 cttcttctga cagaggtaat cctgctggta gtccttcaat aatggctgtt aattctggtc
     4921 catgggattc tcccgcagtc atataacgca tcttacagtc ctcctaagta atctttgaat
     4981 gtctctgtgg gaacaggaac gatttttgct tgcccaatct tttctagcaa gatgatattc
     5041 aattggcttc ctcttgcttt cttatcatgg gttatcgcgt ggaataattc atctggatga
     5101 cttagatcgt acgtaatcgg cagatggaat ttttgaagta tcctttctaa agcagctgtc
     5161 gatccagttg gagacaagcc gattttttct gcatgagaag tgatggctac cattccaata
     5221 gctactcctt ctccatgact gactacccca tatcctgctg tattttcaat tgcatggcca
     5281 attgtatgac caaaatttaa aataagtcga tttccttggt caaagacatc ttcttccact
     5341 acttttcgtt tgatttccaa cgtagcagta atgattggaa cagcatgttc cagaagatct
     5401 ttttcgtctt tcagctcgtt cagctgtttc caaagcgttg catctgctat agctgctgat
     5461 ttgatgattt cagcgattcc ttctcgtaaa cgacgtaccg gcaaagtttt tagaacctca
     5521 ggatcaatca atacaccagc tggctggcta aatgttccga caaggttttt cgctttgttt
     5581 gtattgactg ctgtcttccc gccaatacta gaatctactt gtgcaagtag cgtagtcgga
     5641 atttgaacga aatggatccc acgcatgaac gtcgaggcca cgaatgctgc tagatcaccc
     5701 accattcctc caccaagtgc aagtatccca tcgctgcggg taaaatcatt atctgctaaa
     5761 aaatcgtata actcagctgc ttgttctaaa gatttactgg tctcacccgc cggtacgatt
     5821 gaaaggactg gttcaaaatt agcttgtctc aattggaaca tgattttttc tgcatatagt
     5881 ggagcaacgt ttgtatcagt gatcacagct actttttgag gtctccaaat cgtttgaagc
     5941 catgatccag cctgttctag tgcgcctttt tcaatatgaa tatcgtattt ttggttatca
     6001 acatgtacag taagcattcg tttcacttct ttcttttaaa aagctggaat taatcgagtg
     6061 tctgaatctt ttccattgct tctttcatga tcgcaacttc tttcatcatg cgtgagtaag
     6121 tcttttcatt caacgattgg ggaccgtctg accaagcatt tgcaggatca ggatggatct
     6181 ctacgatcat gccatctgct ccgcttgcca cacccgcacg agccattggt ggtacaagtt
     6241 cccaaattcc tgtaccatga cttggatcaa caatcacagg gaaatgagtt aattttttca
     6301 tcaatgggac agcacttaaa tcaaacgtat tacgtgtcgc tgtttcgtaa gtccgaatcc
     6361 cacgttcgat aaaaatgaca ggagatttgt cttcgactgc aatgtattct gcagcattaa
     6421 gccattcatt gatcgtaccg gaaattccac gtttcaatcc aacaggttta cctgttttac
     6481 cgacagcaga tagcagttta aaattttgca tattacgtgc gccaatctgt aggatatcgc
     6541 tgtactcagc caccatatcg atatgccctt catccatcac ttcagtaatc actttcattc
     6601 caaattcatc agccgcttga cggatgtatt tcaatccttc ttcttctaaa ccttggaaag
     6661 catatggaga agtacgtggt ttgaaggcac cacctcgcag aatttttgcg cccccggctt
     6721 tggccattcg cgcacattct ctgatttggt ctaatccttc gatagaacaa ggaccagcca
     6781 tcgtcacgaa actgccgtca ccaattttta ctccgtctac atccacgact gtattgccag
     6841 gatggaattc tcgagaagtc aatttgtatg tgtttaaaat acgcacagca ttttctactc
     6901 cttcatagcg tgtaaatgct ccttcttgta aacttcgcgt atcacctttt agtccaatca
     6961 ctactcgttc tgttccttga tcgattgaga ctttgaatcc ttctttttcg atatgatcga
     7021 cgactttttt tatttgttct tccgttgctt cttttttcat aattactatc attgtttttc
     7081 ccgctttctt ttgtttactt atctatcttg gctgattttc tctacttttt caaggtggtt
     7141 ttacattaat tcctactaaa tgaccgtgtc ctgttgttct cattttcgct ccttctttcc
     7201 tacttatgac ccagataatc aacaaaaaaa gatgtccctg taggaaattg cctctacagt
     7261 gaacatcttc aacgagcctt aaaaagcgct gcaaaaatat aaaatagcca ctatagatga
     7321 atttctctac gtggctgtaa gtcgtgttta aaaatcttta gccatcatag atacaaacct
     7381 ggtttgtttg tacccacgaa gtcatgaata caaacctatc taaaatagct aaagtaatac
     7441 gtattcagtt ttgtaagttt tctagatttc ataaaaaatc gctccaaact gatgtaagaa
     7501 ttgtacctag tatagacata aaaaaatcga ctgtcaatca tttttatgaa acttttttta
     7561 attttctgat agttaacttt gtttttcaga aaaataacaa ttggttttat tgaagaaaat
     7621 agtcatgaac aaaagtatct gagaactttt ttactctctt gttcatgaca tatagaataa
     7681 agcagctttg tcttgtaaac tccgtttttc aaataataat ctaaagattg ctactgaata
     7741 ataaagccga tttcatggtc ctcttcgctg ctgattcggt aaggtgactc aacatccgct
     7801 ccccagctat tgataccccc gactcctctt acttttgcaa aaatcgtaag aaccgttcgt
     7861 ctttctggcg gtagttcttc tatatgtgtt gcctgttcca gttcttctgc tttgaatggt
     7921 aaagcggaaa aagcaaatgg cgtatcctgc tgttcaaatc gcaacgaaaa atcttcttga
     7981 tctttatccg tattatccaa cgtttgattt cttgttagtt ctacccattt cgtttccata
     8041 tgcatgccgc attcttgggg aacaaggtat ggggaaacgg ggagtcctgc cactttataa
     8101 ataccttcga caccaccagc catccgatcc ggatatgttt cccctgatag gccttcatac
     8161 tcaaaaaatt ttgctttcgt tggcataatg aaccttaaac ccaatgcggg taattccggt
     8221 aatccttttt gtccataata atgcatattg acaagcattt taccctctcc agcgatttgg
     8281 taggaaattg tcacttgggt ttttggtact gtgttgattt ccagtgtaaa aatgatttca
     8341 accgtttcag cgtattcatt acttgaatat tgattattta ctggagcaat cggcaaatcg
     8401 atctttttat tgtccaccag tacttctatt tctttgactt ttggatacaa tccggctcct
     8461 aaccacatac cggatttaaa tccaaatccg ctacctctgt cattatcggt cgttgctcgc
     8521 caaaaaactg gaagtgtttc ccggtatagc cattcttttc cgtttttatt gagcgattcc
     8581 agtccgcctc ttgtataaga aaaaatataa tgcgtattcc ccgatttgac acctaatgta
     8641 cagtcgccga agacgattgc aactttttcc gtatccatat gacttttatt tactgtattt
     8701 ttcataataa tatcttacct cctgcatggc gggtttttct tgtccatctg caaaaacgat
     8761 cccattccct gagaattcat agtcacttgg tttatcgtca aagtcaccgc catagcgcat
     8821 cacttctctg cctgtgattg gatcagtcac ttggatcgcc tgatctttaa aatcccatat
     8881 atagcctcct tggtacattt cataacgatc aagcaacgtc atgtaagaat ccattccacc
     8941 taacgaattc cccatgtcat gcatatattc acataagatg aacggttttt ccgctttatt
     9001 ttcaaggtag tcaatgatct cttctggtgg cgcatacatg cagcttttta catctgaaat
     9061 cgaatcttcg aatgctggat ttggaaaatt cccttcataa tggacaagtc gatcggggtc
     9121 tacttttttg aagtaatcgt tcatttgtcg aatgttttct tccgcataag attcatttcc
     9181 aagagaccaa aaaagaatac ttggatggtt ttttaatgtt tcgaaattcg tttttgctcg
     9241 atcaagaaca gccgcctgcc actgaggtac tgcacctggt acgttgtaag aaggctcaaa
     9301 tgcgcccatt ttttgccatg agccatggga ttcgaggttc gtttccgcca tcacatggat
     9361 tcctgcttgg tcgcataaat aataccaagt gatctggttg gggtaatgag atgtccgtac
     9421 gccgttgatc tttgcatttt ttatgatagc caaatctttt tccatatctt ctatagtgat
     9481 ggcgcgtcct tttttcggat gccactcatg tcgatttacc ccgttgataa tcatccgttt
     9541 tccattgaag tagatgattt tatctttgat ttcgatttta cgaaaaccga aggaatagtc
     9601 aatatactcc gttactcttt tttcttcgtc tatcgtctcc aattcaagct tatataaatt
     9661 gggctgaaaa tgcccccaca gtgccacatt ttcaaatcca tcgatgcgaa tcgtcatttg
     9721 ctcttttaac ggatattgct gttgatagat ttccttccca tcaggatcta gtatcgctac
     9781 attcagctga ctgtttttgg ctacttgctc aaaagacaaa tctacttcaa gtttgccatt
     9841 ttgacatttg tcatctaagc gaggtttgat ccaaagatct tctaaatggt tttgtcctcg
     9901 agcaactaag aagacatctc tgaagatccc aaaaaatcgg aaaaagtcct gatcttccaa
     9961 gaatgcagct gtacttcttt tgtaaacctc cacagctaga atattttctt cttccaaata
    10021 aggtgttaaa tcaaattcag acggagtgaa cgaatcttcg gcatacccga taaaatgacc
    10081 attcaaccaa ataaacattg cttgttctac accagcaaaa tgaatcgaga tttgttttcc
    10141 ctttagacct tcttctaatc gaaaagtcgt caaatacgaa ccaaccggat tgtctttagc
    10201 agctgaaaag atcccttccg cctctttctc agggcttgtc gtgaaagggg gacggcgaaa
    10261 tacatgtccc tcccacggat acatcgtatt gatgtaatgg atcttgtcat aatttgctaa
    10321 ttcaatatga ctaggaacag tgatttcatc aaaagaacag gcatcaaaat cttttttata
    10381 aaatgttttt ggtcgtaccg aaggatttgg cgaataacaa aaacgccatg atccatttaa
    10441 agactgttta agggaggatg tggtttctac ttcttccctt gttgcataac aaacatgatc
    10501 gctatgtgca tttgattggt tcactctaaa aacttgtgga tcatctaacc attttatatt
    10561 tgctttcata cttttttcct tctctctcat aactttttga aatgaagcag ttctgtttgg
    10621 aaatcacctt gaaaatcggg gaagtaaagt ccaactgtca tcaattcggc ccccgaaaat
    10681 atccgcttcg aggtctgttc ctgataaagt gcctcatcat ctaaccccat cagatatact
    10741 tcatggaacg ctggttgagc tgaagctagt atcctcccta aaaacacaat agcttcatct
    10801 tgtttaggag acacaaacat ccatgcggca atattttctt caaaaggact cgccaaacga
    10861 taataatggc catactggat caccggacga atcgtttgat aggatataat ttggtctttt
    10921 acttgctttt cttcttcagg agacagcttt gtcaaatcca gttcataacc aaaaacagcg
    10981 ctcatagctg tttctcctct tgttttcaac gaagtagatc tgtcggtctg atgatttggt
    11041 acagctgata catgagctgt gatggacgaa atcggataag caaggcttgt tccatattgg
    11101 attttcatac gctccactgc atccgtgtta tcacttgtcc atgactgcgg catataataa
    11161 ataaacccgg catcaaaccg tccacctcca ccagaacagc cttcccataa gatttccgga
    11221 taatcagttg tcaaatgttc aagtagttca taaagcccga gcatataacg atgcgctact
    11281 tctccttgtc tctgtgggtc aagggtaatc gaatagacat ctgaaagcga acggttcata
    11341 tcccatttga tgtagtcaag aggaatcgta tctaaaatct ttctcatttg tttctcaatc
    11401 gtctgccgaa catctaacct tgtaaaatcc agtacatgtt gtgatctgga agcagaaggc
    11461 attctacctg gctcctgcat aagaaaatca ggatgtgttc gatacagttc agaatcaacc
    11521 gagatcattt caggttcaaa ccataaacca aatttcaatc ctttgctatg agcataatct
    11581 gctatttcac gtaatccatt tgtcaacttg ccttcatact cgaaccagtc tcctaatgaa
    11641 gaattgtccg catctctttt tccaaaccag ccatcatcta atacgaacat ttcgatgcct
    11701 agctcctttg cttcatcaat gatcgccttg attttttcac tattgaagtc aaagtaagtg
    11761 gcttcccagt tattgaccag aatcggccgt tcagcaaatt gatgacgacc tcttgcgatt
    11821 ctttcacgta gcaactcatg gtggatctga ctcattttgt tcaatccctg acttgagtaa
    11881 gaaaggatca tttcaggtgt ttgaaaagac tggcctgcat tcaattccca cgaaaaacga
    11941 tggctgttga tcccaccgac gactctcaat tgattgatct gatctttttc aagttcgaaa
    12001 gaatggttgc cggaataaac aaattgaagt ccgatcgctt ctccagtatt ttctgtcgta
    12061 tgatgatgaa ctaaagcaat aaagttattc atatggtgac tgctcgttcc tcgacggctt
    12121 tcaaatactt ttgttccaga taaaacagat tgccgtgaaa tctgtctttc attgacatgt
    12181 gctcctggca aagcaatgac ttcatcaaat cgcctagtat gggcaaagtc tagctggaaa
    12241 ctagccgctt tttctagttt gattgtttct ccggtttcat ttcttatctt tacagatcgt
    12301 gtgatcactg ctctatcagt aaatatggta tagaacaaat cgaaataaat cgctgtttct
    12361 ctatccttaa gtgaaatcac caacgtttgt gcctctgact tgtccatcac ataagtttga
    12421 ggcaagcctt cgatctctgg cttcccatct gtaatataat ggctgtcata tctcagatcc
    12481 agtaagtctg atccattctt gcgctgaatg atcgatgcgg gcgttcgaaa gtccatgctg
    12541 ccatgagaag agtattcttg cggtagtgta tctttcgaca gagaccggtc aggatttaag
    12601 ggaacatttc ctgaaaatcc acgatctctt cggggataat ttttattgtc tttgtactgc
    12661 ttgactggtt tgccaaaata aatatgcgcc aatacattgc tttcttctat ctttatcaga
    12721 taagaaagaa atgtatttcg taaatggaag actcggctct tttcatcaaa taagatgaaa
    12781 tttttatctg tttttctatg cgtaatatcc atcatttcac tcccaacaaa acggaaaccg
    12841 tttacttttt tttataattc ctgtatactg tttactaaac aattttgtca ataaaaattt
    12901 tttatttttt tgaggagtgt gtaaaaatgg ttggaattag agatgtcgca cgaaaggcaa
    12961 atgtctctcc tgctacagtt tcccgtgtgt tgaataacga tcagacgatc catgtggctc
    13021 agactactcg gcaacggata gtagaggcag ctgctgcgtt ggattatgac atcagtactc
    13081 gtaaatatat caaaaagaga atgccttcga ttggtgtgat ctctacgatc ggcaaagcga
    13141 gcgaagaaca ggatatctat tacaaacatt tgcgagtagg gatggaagaa gaagctcgac
    13201 gtctgcattt agggatgaat cgaatctata atctatctga taatcctaaa caatgggaag
    13261 atctagatca gttaggtgcg gtgatcgttg ttgggactgt tacgaaagaa tcgattaccg
    13321 ccttgttaaa acaaaacatg caaatagtcg tcgtggataa ccctgacatc cagcaagagg
    13381 tcgatatggt gtatgcagat cttgaacgga tgactaaaac cgtactggaa ttgttcttag
    13441 aaaatggtca taaaagaata gcctatatcg ggggatataa agtcgatatg gatgaattcg
    13501 gtgggaagca gatttctata aatgaaaaga ggatgcgtgc ctatcagcat tttatgatcg
    13561 atcatcactt agaaaaatat atgtcttatc atctaggtgg ctggacagaa aaacaaggtg
    13621 aggtacttgc gactaatcta ttagaaaatg aatcccctct tcctactgcc attcttgtcg
    13681 ggagcgatcc aatggcaatt ggtgtctatc gggcattgaa acaaaaaaat atccaaattg
    13741 gagaagagat tgttgtagca agctttgata atatcgagac aatcgcaaac ctctcccctg
    13801 gcttgaccag tgttcaaatc aatgcgaaat caattgggca agcagctgtt cgaatggcat
    13861 tggagcgaat tgacggtata cgggacgaac caatcatttt gacttatcct gcacgattga
    13921 ttgttaggga aagttttatc ccaagaacaa aaaggtattg aaagagaggt tgtgaaaagc
    13981 cgcttcgttt cttcatactc aaaacgaaac ggctttttca caacctctta cttatactta
    14041 ttcacaaaat ccaatgtctg ctggtaacaa ttttgcgatt cttttagcgt gtaatcaaat
    14101 tggtattcat gggtaatctc tttttttgta tctgtataaa acaaggattg cacgggtacc
    14161 tttaattctg tcaaccgatt ttctaatgct tgaccttgct cctggaatga gtatgcattt
    14221 ccgtcagtta tatacgttgg cggaaattcc ttagaaacat ggtcagccac actagcttct
    14281 ttcaattgct cactcgtttt ccaatctttt gttccaatca acgaccacgc aacggttttg
    14341 acgaaaaact tcataaatcg atcatccgaa tgctgctgtg ctgttagctt caaatcaaca
    14401 ggtccgcaat aagaaatggt tcctttcaga ctatcttttg gaagtagatg tttgattttc
    14461 atttgtttag catacgcatc attcgtttgt atagctgcat attgcaatgc gatttgtgaa
    14521 cctgcactat ctccaccaaa aaataattgt tccatgtcta gcaatttgtc gtctttttct
    14581 tcagctaata aatctttgat cagttcattc acttgaagaa cttgattagg gtattctgaa
    14641 tcaggcgcta attcataatt catcgcaacc actgcgatgt tggcgtctga aactaatttt
    14701 gtcgcaaatt ctttgacacc cgatttatct ccgccgacga atcctccacc atgtacccaa
    14761 aatagaacag gaacaggccc cttgctgttt tttggatagt agatgtcata agtattctct
    14821 ttatacttgg actcatacgt caaatctgtt tttttcgcca cgtttttttc tgcttgatcg
    14881 aacgtttttt tatcagtgat ttgaacagta tttgaaaaca tatggttgat caagaatgct
    14941 ccaggtctgg gggaaagctg gaaggcaaga aagattgcaa acgcgatccc aagaatgatt
    15001 ccgaagaacc atccgataaa tttaagaatt ttctttttca taaggctccc tcagtagtta
    15061 gtattaagca ttctgattat accatagtgt tatttcctat caagctctcc tagatgattt
    15121 aatgattttc cccaaacttc ttctgcaatg cttttgacaa aagaaatttt ttccattgtt
    15181 cttcaaacaa aacattttct tcttctgttg aagcaaatcc acattgagga cttaagcaca
    15241 aacgatccaa aggcagatat cgtgtcgctt cgtagatccg gtcaatcact tgctggtgct
    15301 cttccatttc gccatttttc gttacagtca aaatctaaga caactaattt atcttcagag
    15361 actttctcta aaagaacaaa actcccagca cgttcactat cgtattctaa ataataggca
    15421 cggacatttt cttgagtaaa ataatgggtc tgctacgtcg tcatcccccc tgatgccgcc
    15481 aaaatcgaat aataatttcc gcgtcaaaca tgtatattta gtgttgaatc atttgagaat
    15541 atgaaaataa aaatcttttt gatcaatcag ttaatcaaat tgaaataacg aaaaatctga
    15601 gacagaatga cgttcattct gacccagatt tgattttgca caactcaaca gtccttattg
    15661 gcaaatcgcc aaaataatgt agactaacta aaaagactaa gaaacaataa caaaagttaa
    15721 cacttcttag tctttcttta gcacgtctat ttattaaaga ttttagggcc ttttctcatg
    15781 tttttacgat cattcttagg tgtttccatt tgtttggatc ggcctccacc ttgtttcttt
    15841 ttgatcaatt ctttcatttt ttctttttgg tccattttta ttctccttta acgaatgaag
    15901 cgactaattc gatatgatgg gtttgcggga aaagatctac aggctgaact ttcttcacgg
    15961 cataacctgc ttctgcaaat aacttagcat ctcttgcaaa agttgccgga ttacatgaga
    16021 tatagacgat tcgttctggt gacatttcga ttgctgattc aataaaatga tgatctaatc
    16081 cttttcgtgg agggtcaact acgatcacag atggtttgat ccctttttct tgccattttt
    16141 tcataacttt ttctgctttt ccgacttcat aatgaacatt ttcgatttta ttatttaaag
    16201 cattgaactg tgcatcttca attgcttctg gaataacttc catcccatac accttatcca
    16261 ctctgtctgc taaagacaag ccaatcgtac ctattcctga ataagcgtcg atcacaatgt
    16321 cttttttatc taactcggca aactcgatgg ctgtttggta cagatactct gcttgttgag
    16381 tatttacttg ataaaatgac tttgctgaga ttcgataggt ttttcctaat agctgatctt
    16441 cgatatagtc tctgccatat aaaacttttt ctttgtctcc taaaatcaca tttgtttttt
    16501 cttcattgat attttggatg accgaaacca cttctggcaa ttcttcatga atagcttcag
    16561 caatttcctt ggatttaaag aatttttctt tacgagtaac taaaacgacc atcatttcat
    16621 gggaataatg accacgacgg ataatgatgt gacgaagctg tccttcattt ttttcttcat
    16681 tatatcctcg tacttggaac cgttgcaaga tatctctgac tactttgatt gcttgatcga
    16741 tgacaggatc ttggatataa aaatcttcga tagggactag atcatggcta ttctttttgt
    16801 aaaaaccggt ggctaactgt ccatcgatac ggcgaacagg gatctgtgct ttattacggt
    16861 agccgaatgg ttctgccatt ccgaccgttg gaagtacagg aacttctggc atcttagcaa
    16921 tcttcgccat tacatgctct acttgttttt gtttgaagac aagctgttgt tcatacttca
    16981 aatgggctaa aggtgcgata cctatgcgaa gtaatgcatt gttttctaca ggctgacgat
    17041 caggtgattg tgtaataaat gtttcgactt ttccatatcc aaacttattg cctgctttta
    17101 ctactagtat ttctacttct tctccaggga gtgcattttc gataaataat ggataaccat
    17161 cgatttttgc tacccccatt ccttcataac tcaagtcgac gatttcgact gtatatcgtt
    17221 cgtttttctt tactatttgc tgttctgtca tattttgctc ctttaagcct atttttcaat
    17281 cctactgaac tctactataa atcagctaat tacacaacta aaaccggcac tgaccttact
    17341 acgttcagca ccggcttttg attaattctt ttgattaggt gtttcgtctg ctatttttcc
    17401 gtcaccgtcg atatcttcat ccgttaaacg ttcgacttct tttacgaatt ctttgctgac
    17461 aacctctaat tcttcttcat ctgtacctgt gattgcttca tcaggaatct gatcggtatt
    17521 ggcaaagaac tcaatgtgtt gatgaagatt ttggaaatgc atcggtgctt ccccgccgta
    17581 ttcaccatct aagttgatca ttactggtcg attgatatca tcttctgttt caacgaacaa
    17641 actgcttgtt ttggtataga ttattcttgg atcatcggca tgtcgaccgc cattcagcat
    17701 gagtgctgca atatgcaaga tctcaaagat atttgctgtc ttcacaatga ttaaagaaaa
    17761 cttcccatca tccaatttgg catctggcgc gatctgttcg aatcctccaa cagagttcgt
    17821 cagccctagg aaaaacatcg aagcatttcc gatatattcc ccttcatcat acttcaagcg
    17881 cattttgatt ggctttactc gagggagcat ctctgctcct ttcgcaagat aagcaagata
    17941 accaaaaata ctctttagtt ctgatggaac ttcataagtc aattctgtca aatagccacc
    18001 tgcagcgata ttgatgaagt aactgttatc agaaaggccg atgtccattt ttacggtttg
    18061 gtgttttttt atcacttctg ctgctgcttt aatattatct ctaggaattt ttaatgctcg
    18121 agcatagtcg ttcgttgtac cagctgggat gatggccatt ttaggacggt gttcaagcgg
    18181 agcgattcca ttaaccactt cgttgattgt gccatcgcca ccagctgcca ctactagatc
    18241 aaaacctagt tctgcgactc tacatgcttc attcttggct gaatctggtt ctggtgtagt
    18301 tgcataggcg ctggcttcaa atcctgcttc ttctaatgcc tgtaggatat ccgccaaatt
    18361 ttttttcaat aattcttttc ccgaggtggg gttataaatt acgcgtgctt ttttcatttt
    18421 cagcctctat cgtttcgcta attcatcttt aagtagctta ttcacgacac caggatttgc
    18481 ttgtccttta gttgctttca tgatttgacc gactaggaag ccaaccgcac gatcttttcc
    18541 atttttgaaa tcatcgacag attgttggtt gttatccaaa atttcattaa tgattggcag
    18601 tagtttgttc ggatcagata attgcaccca accatttttt tcaactactt cttgggcttc
    18661 tccgccattt gtgatcaatt cacggaagac ttttttggcg atttttgagc tgatcgttcc
    18721 atcggcgatc aaacgaatca ttcctgctaa gttctcaggt gtcaattttg tctcagctaa
    18781 ttccagtttc tcactgttca agtaagcaga aacttcaccc atcaaccagt tagatgcttg
    18841 cttggcatct gcaccatttt ccaaaacagc ttcaaaaaaa tcagacattt cttttgtaag
    18901 tgtcaatacc attgcgtcat actctggaag tccaaactca cggatatagc gttcgcgacg
    18961 agaagctggc atctcaggca aactagcttt tactttttga atccattcgt catcgatcac
    19021 gaatttcggg atatcaggct ctgggaagta acgataatca ctagaccctt ctttgacacg
    19081 catcaaaact gttttattcg ttgtttcgtc aaaacggcgt gtttcttgtt ggatttctcc
    19141 tcctgaaaga agaacttttg cttgacgttt ttcttcaaaa gctaaacctt ttttcacgaa
    19201 agataaagag ttcaagtttt tcaattctgc tttcgtaccg aactcttctt gtccataagg
    19261 gcgaagagaa atattggcat cacagcgcat agagccttct tccattttca catcgctgac
    19321 ttctgtaaat tggataattg atcgcaatgc ttctagataa gcgtatgctt cttctggtga
    19381 acgcatatca gcttcagaaa cgatttcgat caaaggcgtg ccttgtcggt tcaaatcaac
    19441 gtaagaataa ccgccaatac catgcatgtt ttttccagca tcttcttcta aatggacacg
    19501 ttcgatccgg atttttttct ttttaccttc tacttcgatt tcgatccatc cgtcatgacc
    19561 gattggttga tcaaattggg aaatttgata tgcttttgga ttatctgggt aaaagtaatt
    19621 tttccggtca aaatgagtat ctttagagat ttcacagttt aatgccaaag ctgctttcat
    19681 cccgaattcc agcgcagctt tattcattac tggcagcacg cctggataac cccagtcgat
    19741 cacgtttgta ttgctgtttg gttctgcacc aaaatgagct ggcgctggag agaaaatttt
    19801 tgagttggtt tttaactcga cgtggacttc tagtccaatg actgtttcaa aattcattcg
    19861 tctttccctc ctaaaatagc tggttgttgt ttatggaatt ctgttgcttg ttcaaacgca
    19921 tatgccgctt gatacatcgt tttttcatca aaataattac cgatgatctg caatccaact
    19981 ggtaatcctt ctgataaacc tgccggtaca gacatacctg gaagtccagc caagttgaca
    20041 gggatcgtta agatgtcact catgtacatt gtgattggat cgttaatgtt ctcaccgatt
    20101 ccgaatgcaa ctgttggtga agatggcccg atgatcaagt cataatctgc aaagactttt
    20161 tcaaaatctc gtttgatcaa tgtacggact tgtcctgctt ttttgaagta agcgtcataa
    20221 taacccgcgc ttaaggagaa tgtacctaac atgatacggc gttttacttc ttcaccgaat
    20281 ccttctgaac gtgagttgac atatacatca tctaatgatt tcacattttc agagcgataa
    20341 ccgtagcgga taccatcgaa tcgttgcaaa ttggaacttg cttctgatga ggcaatgata
    20401 taataaacag ccacaccgta ttttgaatga ggcaagctga cttcttccac aacagcacct
    20461 aatgaacgga atgtttctgc tgctttcaat acagcttctt ttacgccagg ggccacacct
    20521 tcgcctaagt attctttagg taaagcaatc ttcattcctt tgatgtcgcc tgtcagtccc
    20581 tctgcaaaat caggaactga aacgcctgaa gaagtaccgt ctttttcgtc ataaccgctg
    20641 atagctgtca atgctaatgc attatctttc accgtacggg tcattggtcc gatttggtca
    20701 agagatgaag caaaggcaat caaaccaaaa cgtgagacac ggccataagt aggtttcatc
    20761 cctacgatgc cgttaaaagc tgctggttgg cggatacttc ccccagtatc actacctaaa
    20821 gaaactggaa tttgtccagc tgcaactgct gctgcagaac caccagaaga gccaccaggt
    20881 acttttgttg ggtcccaagc attttttgtt ttcttgaaat aagaagtttc tgtacttcca
    20941 cccatagcaa attcatccat gtttagctta ccaacaggga tcatatctgc ttgatagatt
    21001 ttatccatga ccgttgcatc ataaattggt tcaaaattgt aaaggatctt agatgcagcg
    21061 gttgtcaaga tatcttttgt tacgatatta tccttgatac caattggaat accagcaagg
    21121 acgttgcttt catcaatccc tttttcatct aaagcttttg cctgttccaa tgctttttct
    21181 tcgttcaatg taatgaatgc ctcgacctca ggctctgttt ctttgattcg ttcaaatgtt
    21241 gtttttgtca aatcttgtac agtgatttct ttcgatacaa gcatatgatg cagttcttct
    21301 agagaacgat tgtgtaattc tgtcattatg cgccagcctc cccattatcg atgattgcgg
    21361 gtactttgat aaagccgtct tctgtttccg gcacattttt caataattca tcgcggttcc
    21421 atccagcttg cgcccgatct tgtcgcatca cgtttactgt ttcaaccaca ttcgacgtaa
    21481 atggaacacc ttccgtatct acttcttcca gcatttcaac catatcgatg attttaccta
    21541 attggtcggt aaaacttgca agttcttcat ctgcgaacgc aagttttgct aatttggcaa
    21601 cgtgtttcac ttgttcttca ctaatcgcca tactacccct tctttctaaa cgagttaaaa
    21661 actttgctct ctattttaac acaagagtgc cgtgtctgaa attgtttatt gaaatttgtc
    21721 tgaaaaaact catttttcat tcttctactg agcgactttt agccaatgca tctgccattt
    21781 gatcttctgt ccaaacttcg attcctaatt cttgtgcttt ggtcagcttg ctgccagcat
    21841 cttctcctgc taccacgata tccgtttttt tcgatacgct accagtcact ttcccgccaa
    21901 gattttcgat cgtctctttt gcttcttcac gagtaaatcg tgttagttta ccagtaagga
    21961 ctactgtttt ttctttaaaa ggagactcga cttcttgcaa ttgggcattt cgaagccctt
    22021 tgtattcgaa attgacgcct gcttgtttta attcattcat caattcatgg acttcttcgt
    22081 tactgaaata agtgactaca ctgtcggcaa tgatatcacc gatcgtatca agcgcaataa
    22141 tcgactcata gtcactttta ctcaatgttt ctagatcacc gaaatgttct gctaaaattt
    22201 ttgctgcttt cgctccgaca tgtcggattc ctaacccgaa aatcaaccgc tcgaccgaat
    22261 tatctttgct gttgtcgatt gctgtcaaaa tattatttgc tgatttttct tttattttgt
    22321 ccaacgtcaa taactcttct tctgtcaatt tgtaaagatc agcaacatct gctactagtt
    22381 ttttatcata catctgttct agtacgcgcg gccccaaccc atcgatattc atcgcatttc
    22441 ttgaaacaaa gtggttcaaa ccttctttca tttgagcagg gcatttagga ttgatgcacc
    22501 gtaaggctac ttcttcatcc aaatggacaa gttcacttcc acaaactgga caatgtgtag
    22561 gcaattggta ttcttcgctg tctttaggtc gtttatctaa cacgacttgc gaaacttctg
    22621 ggatgatgtc tcccgcttta taaatcagaa ctgtatcttt caagcggata tccttcaact
    22681 taatataatc accgttatgc aggctggcac ggcttactgt cgttcctgct actcggactg
    22741 gtgtcatgat agctgttggc gttactaccc ctgttcgacc gactgtccat tcgatgtttt
    22801 cgattagcgt ttcaacttct tctggcggaa acttgtaagc tgctgcccat ctcggtgctt
    22861 tgatagtaaa accaagttga tcttgtagcg agaattcatt cactttgatg acgattccat
    22921 cgatttcata gggcaaatcc acacgtttgt catgatattc ttcaatgtat gaccacactt
    22981 catcaatcga atgacataga cgtttttccc gattcgtgtg gaatccaatt ttttctagct
    23041 cttctagcgc atcatactgg gtttttgctt gcataggacc gaaatcagct actgtgtata
    23101 aaaaagtgtc cagatttctt ttcgctgtga ttttagaatc taactgacgc aaagaaccag
    23161 ctgcggcgtt ccgaggattc gcaaagatat cttttccctc tgcttctctg tcttggttca
    23221 attggacaaa tgaccgtttt ggcatgaaac attcgcctct tacttcgatg ttcattggtt
    23281 cttttaattt gattgggacc gaccggacag tttttaggtt ttcagtgatg ttttctccta
    23341 cagttccatc cccgcgagtc gcacctctca cgaaatttcc atcttcataa cgcaaagaaa
    23401 cggaaagtcc atctattttt agttcacagc aatagtcaac tacacgtccc actgcttttt
    23461 gtacacgttg atcaaaagct atcagctctt ctttgctgaa aacgtcgttc aaactgtaaa
    23521 gcggaatatc atgagtgact ttttcaaaac cttctaatac ttttccgcct actcgttgag
    23581 tgggagaatc agacgtgatc aaatcaggat attgttcctc gattgctact aattctgcgt
    23641 attctttatc ataaacatag tcttccactg ttggtttatc ttctacgtag tattcgcgag
    23701 accattggtt cagtcttgta cgaagttctt ctgctcgttt agcagcttcg tcaatcgtca
    23761 tttcatgttc catcatttac cctccactac taagcttttt caattggcgc aaaggcagcc
    23821 aaaagacgtt ttactccttg acttgggaaa gccacatcta gttctagatc cttcgacgtc
    23881 ccgcttactc ggacgactgt tcctagaccc cattttttgt gtttgacttt atctccaggt
    23941 ttccagctgt tattttcccc tccagtagca cttttagagg gaacaaccgc tgtctctggc
    24001 tgtttatagc tatatgctgt ttttttagcg aatacaggcg tttttttagg cgtaggacgc
    24061 atgccttcga tttccagtaa ctcctgatcg atttcttcta caaaacgaga aggtcggtta
    24121 tattgcgtcc gtccatataa tgttctggag aaagcatttg ttaaatacaa cgcttcttct
    24181 gctcgcgtga tccccacata tgcgagacgg cgttcttcct ccagttcgct ttcttccatc
    24241 aatgctcgag ataaaggaaa aaccccctct tctagaccaa tcaggaatac aactggaaat
    24301 tctaatcctt tggctgcatg caaagtcatc aatgtcactt gggaagcatc ttcttctaaa
    24361 ttgtcaatgt cggaaacaag tgccagatca tttaagaaga ccgttagttt ttcttctggt
    24421 gcatcagcgt cttcttcatt ttgctgttcg aattgtttgt cgaattcttg tgtgaccgtt
    24481 aaaaattcct ccaagttttc gatgcgtgct tgtgcttcta atgtattttg gatttttaag
    24541 tcttctagat atccgctacg atccaaaacc tctttcgtca attctgtcac tgtcaagtat
    24601 gggatcatct gagtgacttc ttggatcatc tctccaaatg cacctaattg ctgtcctgct
    24661 tttccaccga tatttgccag atccacattt tgcgctgctt caagcagtgg ccattcatga
    24721 agagaagcaa aactgcgtag tttttcgata gatcctggtc cgatgcctcg tttgggcgaa
    24781 ttaacgatac gctcaaaact gattgaatct tgaggattta ccagcacatt caaatacgct
    24841 aaaatatctt tgatttcttt acgatcgtag aacttgtgcc ctccaaccat tttataagga
    24901 atatttgctt tcaacagagt ttcttccatt acacgagatt gtgcgttcgt ccggtacaag
    24961 atggcaaagt cgccgtaatt ccgatgattg cttcgaatct cttcttgcat ccggtctacg
    25021 ataaaacggg tttcgtctcg ttcattatct gcacggtagt aagtgatctt gtttccttct
    25081 ttgttttctg tccacaagtt ttttggtttt cgattgctat tgttttcaat gacttggttt
    25141 gctgcgctaa ggatgttttt cgtggagcga tagttttgtt ctagcaaaat tactgcagca
    25201 tctggataat ctttttcaaa atccaagatg ttctgcatat ctgcaccgcg ccagccgtaa
    25261 atactttgat ctgcatctcc cacgacgcac aggttcctaa atctacctgc caataaattg
    25321 actagcgtat actgtgcgtg atttgtatct tggtactcat ctacatgaat ataatggaat
    25381 ttgttttgat aatacgtgag tgaatcagga tgttcttcaa ataatcgaat cgtattcatg
    25441 atcaggtcgt caaagtccat acattgatta tattgaagct ctttttggta agcagcataa
    25501 cattttgccg caatctcttc gtaataactg ccttgcattt ttgcaaaatc ctgaggggtc
    25561 tgcaggctgt tttttgcttg agagattgtt cctaatatac ttcgaggatc atattttttc
    25621 ggatcaatgt tcagttcttt tagtatccgt ttcatcaagg tcagctgttc agaagaatcg
    25681 atgattgtaa agttccggtt atacccgata aaatcaacat ctcttcttaa aatacgcaca
    25741 cacatcgagt gaaaagtcga tacccagaca tcttcgcctc cagatgcgag aatcgcattg
    25801 acacgttctt tcatttcttt tgcagcctta ttggtaaaag taatcgctag gatgttccaa
    25861 ggattgactt ctttttcctc aatcaaatag gcaatgcggt gtgtcagcac tctcgtcttt
    25921 ccacttcctg cacctgccat tagcagtaat ggtccgtcag tgtgaagaac agcttctttc
    25981 tgacgggggt tcatcccgtt taataattca gctttggatg acattaacaa catcctttct
    26041 tttatcaatc ttgttaatta tagcattttc ttggctttca ttaaactagc tagttcaaaa
    26101 tcatttgttt ctttttatgg atttttcctt gtcaattcgt tgatttcgcg ctaaattaaa
    26161 agaaagcgag gcgtttgaat ggaaaaaaaa ggaaaaatca agaaattaga taagactcag
    26221 atatatttta ttctaaaagg aatatttgtt ggactgctga caggaatcgt cgttagcctg
    26281 tttcgattat ctatcgaaaa gctaagcgat ttagttcgaa gtatctatga aatgagtcgg
    26341 gaacagccga tttacttaat tggcctagct atttgctgca tccttgcagc atttttcgtg
    26401 ggttatctgg tcaaaaatga accggatatc aagggaagcg ggattccaca agtagaggga
    26461 cagcttcgcg gggaattatc aatgaactgg ttctctgttt tatggaaaaa gttcattggc
    26521 ggtgtacttt cagttggtgc gggccttttt ctaggtagag aaggaccttc tatacagctt
    26581 ggcgcatcca ttggacaagg agctggacaa ttgtttcgga gtccatcttc agaagaaaag
    26641 attttaattt ctagcggtgc aagtagcgga cttgcagcag cattcaatgc tcctatcgca
    26701 ggattactct ttgttttaga agaaatccat cactcctttt ctccacttgt ttggctgaca
    26761 tcatttgctt cagcaatcac tgctaacttc gtctctcttt actttttcgg cttgagacct
    26821 gttttatatc taggtgacct tccttctttg ccgttgaaat attatggttc cttagtgatc
    26881 ttaggagtac ttctaggcat cttaggtttt atttatcaga atgtcttgct ggctttgcca
    26941 aaattttaca accgattgcc tttaccagct tattttcacg ggttcgttcc tttcttgctg
    27001 attttgccaa ttggttattt atggcctagt actctaggcg gaggcaatca aatcgtttta
    27061 gcttttggac atgcttcctt gccaatcatt atgattatcg gtttgtttgt tcttcgattc
    27121 gttttttcca tgatttctta cggtgggggt cttccagggg ggattttcct tccgatattg
    27181 acattggggg ctttaatcgg tagcttttat ggaaacatta tggttgattt cgggatggat
    27241 ccaatctaca tcaaggattt tgtcgttatt gccatggctg gttatttcac agcgattgga
    27301 aaagcaccgc tgacagcaat tattttagtg acagaaatgg ttggctctct taatcatctg
    27361 atgcctttag gattggctgc tcttgttgct tatatcgtca atgaccttct cggcggtaat
    27421 ccaatttacg aatcattatt ggaacgtcta cttggaaata ctcagaccgc ctcactaaaa
    27481 ggtgcaagga caacttttga ttttccagta acggcagaga gttctttaga cggattaatg
    27541 gtacgagact tcaattggcc taaaaatatg ctgctaatct ctatacgcag aggaaatcag
    27601 gaaatcttga ctcacggtga tacgatcatg aatgtaggag atattttggt tatcttgact
    27661 gatgaagcaa acttgccaag aatcaagcag gaaatcgagg ctaaatcttc tatcacaaat
    27721 ttgaagcaat cattttaacg aacatggaaa aactatttta caacaactat tcatctacac
    27781 tacttgattc tatatgattc tataaaaaag aagaggctgg gaaaacccag cctcttcttt
    27841 tttatttcta tgcttctgct actgcaggag cttttctcaa taaaccataa atcacaccag
    27901 atacgactgc tccgatagca ataaacacca aatacatgac cgggtgactc agtaagaata
    27961 caacgaaaat cccgccgtga ggagccagta atttgattcc gaaagctccg actaatccgc
    28021 cagttaaagc agaaccaata ataaaacttg gaatggcacg aatcgggtca gctgctgcaa
    28081 atggaatcga tccttccgtg acaaacgata gtcccatcac gatgttcgtc aaaccagcat
    28141 cttgatctgt tttgctgaat ttattcttaa acaaacgtgt agcaacgaaa attgccaatg
    28201 gaggtaccat tcctccagcc ataacagaag ccatcacgac acttccgcca gttgcaacag
    28261 tcgtagctaa agttgctgta ccaaacacat aagcggcttt gttgattgga ccgcctaaat
    28321 ctgccgccat cattccagct aataatgcac caagtaaagc agcattcgaa ccactcatac
    28381 ttgtcaagaa accgttcaat gcatcattga ttgctttcat agggacattg accagcaaca
    28441 tcaagaaacc agtaatcagt aagccaaaca ctggataaaa gaggatcgtt ttaattccat
    28501 ccaatgattt tggtaagttc ttgaataatt tacgtaaaaa tacgatgaca taaccagcta
    28561 agaatccacc aatcagtgca cctaagaatc ctgcaccgcc tgtattagct aatgcaccag
    28621 cagcaaatcc aacgatcaaa ccagggcggt caccgatact tgaagcaata aatcctgcta
    28681 ataccggcag catgaaacca aatgcagctt gtccgatttg gttgaaccag ctagcagctt
    28741 gattgtaatt ccctagattt gataattgat catgtggcac gccaataaat tggtcgatca
    28801 tgaaagaaag cgcaatagcg attcctccac caataacgaa aggtaacatg tgtgatacgc
    28861 cgttcatcaa atctttgtaa attctttgtc cgatagtacc atccgcattt ccttcttctg
    28921 aactgctttc ttttccatca ccatggaata ctggtgcagt accactaagg gctagattga
    28981 tcaactcttc tggtttacgg ataccatcac tgacaggacg attgatcagt tcttttccgt
    29041 caaagcgatt catctctact tttttgtctg ctgcaacgat tacaccttct gcacgggcga
    29101 tgtcttcagc agtcaatcgg tttttgattc cttctgaacc gttcgtttcg actttgatct
    29161 ccacacccat ttctttcgct tttttcttca aagcatcttc tgccatgtaa gtgtgagcga
    29221 tccctgttgg acaagctgta acggcaacaa cgaattttct ttctggatga gcagaagctt
    29281 ctgcagcttg tgtttcttgt tctgcttttt cttctgcttc tttttgctct tcagctgttt
    29341 ggaacaagtc ttggacttct tctggtgtat ttgcttcttt taattttcct acgaaatctg
    29401 catcaatcag caatcgagat agtgctgcta atgcttgcaa atgtgtgtcg tttgcgcctt
    29461 ctggagctgc gatcatgaaa aacagataag ttggctgtcc gtctaaggct tcataatcta
    29521 ctcctttttg gctttttgcg aataaaactg ttgcttcttt aactgcactg tttttcgcgt
    29581 gaggcatggc gattccatca ccaagacctg tagaagtttg tgcttcgcgg gctagaattc
    29641 cttctttata tgtttcgata tcggaaatcc ggccggcatc aaacattttt tggaccattt
    29701 catcgattgc gcctttttta tcagtcgctt gcaaatccat gatcatcgct tctttgacca
    29761 ttaaatcctt gatattcatg attatcctcc ttgaaactaa tcaatttttg tgatttcaac
    29821 ttctggcagc aactcatcaa tcaattcgcg agctgccaag tcatcagaaa aagctgttgc
    29881 gcttccgcaa gcaactcccc atttaaaggc ttcgattgga tctttcgtac ggctgtaagc
    29941 cccaataaag ccagcaatca ttgaatcccc tgcacctact gaatttttca atgggcgaac
    30001 taatacattc gttttataag ttccttgttc cgtgaagagc aaagcaccgt ctccagccat
    30061 tgagatcagc acattctgtg ccccttcagc tagtaatttt ttcccatacg gaatgatttc
    30121 ttctacagat tggaaggttg tgttgtaaag ctcagctaat tcgtgattgt ttggtttgat
    30181 caacaacggt ttcttaacaa gtgcattttt taggtcatca cctgttgtat caatcacgaa
    30241 atctgcacct ttttctcgaa tgatatcaat cagttcttga taaaatcctt ttcgcaggct
    30301 agctggcgcg cttcctgaca atacgacgat atctccttgt cctactgttc ctaatgcttg
    30361 cttcaactca tcgatttctt catctgaaat agatgggcct aagccattga tctcagtttc
    30421 agtgtctgat tttagtttga tattgattct tgtatcttct tttacggttg tgaacaaaga
    30481 ctggatttgt tctttttcaa gccacttcga aataaattcg ccagtgaacc ctcctaaaaa
    30541 ccctagtgct gtagattgag aatcgatccg tttcaaaata cgggaaacat tgatcccttt
    30601 tcctccaggt aacttgaagt cttccttcat tcggttcaaa tcgcctagtt ttaacccatc
    30661 tacgcgtacg atataatcaa ttgatggatt aagtgttact gtgtaaatca ttgtattgcc
    30721 tccttaattg ttgtcttttc acggaattca ttaacgaatt ctaatggaca acgctcggtt
    30781 atgatcgtgg ctgcttccaa aggtgcaaca gaggtgaagg acaactggtt gaatttggta
    30841 tgatcaatca atacaaatgt ctcttcggaa tttttcatgg ctaaacgttt aacagctgcc
    30901 tcttctggat ccggagtcgt gaatccttgt tcaagatggg caccgttcat tcccataaat
    30961 gctttattaa aatgaaaatt ttttagttgt tctatcgcat tagatcctaa aacagcatta
    31021 gttgccagct ttatcgttcc acctaaaata atggtagcaa gctccaaatc aactaaattt
    31081 gccgcatgtt gaacggaatt tgtcactact gtgatctgtt ttccttgcag aaaaggaatc
    31141 atttctaacg tagtagagcc agcgtctaaa taaatgacat cttcgtcatt aatggtttca
    31201 gctgccgatt tggcgatttg ctgtttttcg tgaacgtttt tgagtgattt ttcactcata
    31261 ttctgctcaa aattcaataa ttgctctttc ttagctccgc catgaactct ttctagaaac
    31321 ccactattct ccagctcttg taaatcacgt cttatcgttg attcagaagc attcaaaagg
    31381 tttacaagat cttgtgattt cacgattttc tgctgttcaa gcaagtctag gattttttgt
    31441 ctgcgttcct ctgtaagcat tttcacgatc acctcaatac aaataatagc atattttttt
    31501 tctactagca atataaatca gtcaaaaacg ttcataaaag ttataaatca gtcaaaaaaa
    31561 aaaataaaaa accagtcaga aagactggtt ttttattttt ttgtctatca tcaagccgtt
    31621 ttatcgtttt ttattttcgc ttcttgtttt tttcatataa acagaagcag gttttctttc
    31681 cttatgaaga agataataat aaagtcccat cccgccaaac atgaccaaaa aaccgatgac
    31741 tgatcgaata ggaaaattag gaacaaaaaa gagacagacg gataataatg atgccggaac
    31801 cattattcga taatagagtt gtttatccat tttcttcacc tcatattttt tgtaaagtaa
    31861 tcaattgttc taattctcgg taatctaaaa attgcacacg cagatgctgc tcacctttct
    31921 tgacatcgaa ttggatactt cgccgctttt tctttattcg tttgaaggta acatcagaga
    31981 gtctatgttt gatttccttt aacggtaatt ctgacaggga ttctgaagga acatagattc
    32041 ttaaggataa aagatactct tgatattttt catctgttac ctctacttct agatattccc
    32101 taatataata acaataagct tcgattccat tatccaaagc aacagtcgga tcgataactt
    32161 tatagcacat catgcgtgat cgattctcgt caacccaagg aaaatacgcc tgagcattta
    32221 gtgttccgcg aacacgcctt tctttataat ctccttgttg gatatcataa ctttttgtta
    32281 caaaaaatga agcattcttt ttaggaacag gttgcatttg tgcattctga tactggacag
    32341 attggatcgt atggtcagtg taaatgtatt caacgaatgg cggtttcaat aaaccgacac
    32401 cattgtccca agcaagatga tcaaacccaa gctggtccct aaaataggat tgaaacattt
    32461 gattgtttgg cttttgccag ttaaaggggt ctcgataaag ctggatacat atgacttcgt
    32521 tttctaattc cttcactttt tctacttgtt ggatgtcgag aaaaatcggt ttagggatga
    32581 tttgatgata atagcgacta taatacattt cccaacacga agtgaaacat aaaccttggt
    32641 aaaaaagatc gtatcctgga aattggttgc aatcgactac tacttccccg ttttgttgtt
    32701 tcattttagg taaatgttcg atttcatcct ttttctcaaa caatagccgt tgagagatct
    32761 gttttgtatt gtgatagata aactcgctat aagctcgcat ataggcgaac accccatgag
    32821 caatcatttt tttctgaatg aagtctcgaa tcaaaaattg cttttctttg aaaacagaga
    32881 tagacaatac attttttatc aataattgat tatcttccaa gcgaaaacta cattcgttct
    32941 cgtcatttcc tacaactaac caactttcgt ctcttaccga tgctagcatt attttttctt
    33001 gaagctttcg aagatcatac ggatccgctt gttgtgtgaa agagcggata aatgttggct
    33061 ggatcaacag acgtgtcaaa atagcccaat cgcttatttc ctgttttttt tcttcttcat
    33121 ttaagtctgt gagctggata gtcatcaata atttatcttc gccaatcatt ttctcacctc
    33181 tttcaaatct ttttataatt taattataac caatgataaa gaaaaactaa aactttatgt
    33241 cttagaaacc aatttggacg attacatgat agactaagta aaaagaaaca aagaggtgtt
    33301 tacaatgggg ttgaaatttg aacgtacaga taatttagat aaacttttcg aatcatttgc
    33361 tgtcgatccg gaaaaaacag ttgcaccaaa agaagagatc gatcgatttc taaaaccaca
    33421 gccacaaaat gaaaagaaaa aagacaagaa acaaaagtaa gttaagctca aaaaaagact
    33481 taccagccaa acttttatga aagagtttga ctggtaagtc ttttttattc tttttatgat
    33541 tcaattgctt gttcgattgc tgcccacgct tcttcttttc cctgttttgt aacggaagaa
    33601 aagagaataa acgtgtcatt gcgatcaaaa tccaacgctt ttttgatttc gctctcatgc
    33661 ttgttccatt taccacgagg gatcttatct gccttagtgg caacaacaat tacagggata
    33721 tcataatact tcaaaaattg atacatctgg atatcttctt gagaaggctt atgacgcaaa
    33781 tctactaaag aaacgaccgc acgtagctgg tctctagtcg ttaaatatgt ctcgatcatc
    33841 tttccccatt ttgctcgctc agttttggat acttttgcat acccatatcc cggaacatcg
    33901 acaaaatgta atgcgttctc gatcaaataa aaattcaatg tctgggtctt tcctggctta
    33961 ccggaagtac gggctaaatt ctttcgatca atcaatgtgt tgataaaaga agatttccct
    34021 acatttgatc gtcctgccag agctatttct ggcaattgtg tatctggata ttgttttggt
    34081 gccactgcac ttatgataat ttcagcttga tggactttca tggtctctct ccttaacaag
    34141 gtgatgaata aagcaagcgg ctgtcgcaaa agccaaaatg acttttacgg cagcctcttt
    34201 tcatcaaccc gcttttttct ctgaatcttt atagattact gttggctcac cagacaattc
    34261 agctgcttct tttgtgataa tcactttttc gatgttttca tttgaaggga tatcaaacat
    34321 cacatccatc atgatttctt caatgatgga acgaagtcct cgagcaccgg tattgcgttc
    34381 gattgctttt ttcgcaatgg ctctcaacgc ttcaggttcg aattcaagtt cggtattatc
    34441 tagagaaaga agtttttgat attgtttgac tagcgcattt ttcggctcag tcaagatccg
    34501 taccagatca tctgttgtca atttctctaa agctgccata acaggtaatc gtccgataaa
    34561 ctcagggatc aatccgaatt ttagtaaatc ttcaggaatg atatgctgca tgacactttc
    34621 gtcttcagaa agtttttggt tttgtgtacc aaatccaatc gtcttttcgc ccatacgatt
    34681 cttcacaatc gtttcgatgc catcaaatgc accacctacg atgaacaata tgttcgtcgt
    34741 atcaatctga ataaattctt gatgtggatg tttacgtccg ccctgaggtg gcacacttgc
    34801 aacagttcct tctagaattt tcagcaaggc ttgttggaca ccttcgccgg aaacgtcacg
    34861 agtaatagat acattttcgc ttttacgcgc aattttatcg atctcatcaa tatagatgat
    34921 ccctttttct gcaagttcca cattgtaatc agcagattga agcaatttaa gcaaaatgtt
    34981 ttctacatct tcccccacat aaccagcttc tgtcaaactt gtcgcatctg cgattgcaaa
    35041 aggtacattc aatgtttttg ctaatgtttg tgctaaaaat gttttaccag accctgtagg
    35101 tccgatcaag cagatattgc ttttttgcag ttcaacatca tctgtgtttt cttgtgcttg
    35161 ctgattgaca cgtttatagt gattgtatac ggcaacagct aacgagcgtt ttgcgcgatc
    35221 ttgtccaatc acgtagttat tcaatacttc aagaatttct agtggtttag ggacttcagt
    35281 gaattcgcgt acagcttctt cataaaattc ttcatcaatg atttctttac ataggtcgat
    35341 acattcatta cagatgtaga cccctggacc agctacgatc tttttcactt cttcttgggt
    35401 tttcccgcaa aaagaacagc gtacggtctc attgctactt ggattgtcat acatggtctt
    35461 caccccttaa cttgcaaaaa gtatgcaaga aactatcaaa gactttacag tcttttacta
    35521 tcataacata gtttagtaaa aagaaaaagt gtttaacaaa ggatcaactg acctatacct
    35581 ttgcattttt tactcttaac aaaaaataag gaactgtgac aaaatcgtgt cacagtccct
    35641 tatttcgaat aaacaatttt ctagaagtag cttcttcaga aatgatttat tacttgattt
    35701 ctattctttc gcttctgtcg ctgtacctgt gatcaattcg attgcttttt tcattgtcac
    35761 atcatgttcc agcatatctt ctgtcaacac gcgtttgatt tgttcgattg gcatgttgta
    35821 tgtttctgat aattcttgga tttctgcatt gatttcttct tctgttgctt gaagattttc
    35881 agcagctgca attgcttcga tcacaagatt tgttcttgtg cgcatttctg cttcaccttc
    35941 gaattgttta tgcaagtctt cttctgtaga accagttaat tgatagtaca tttcaggaga
    36001 gataccttga cgttgcatgt tgttcaagaa ttcgtccatt gaacgatgta cttcatcatg
    36061 aaccatcacg tgtggcaatt caacgatttc tgcgttttca acagccatac ggatcgctgc
    36121 ttcatctttt gcatcgtccg ctgctttttc ttttgtttct actaattctt tgcgatattt
    36181 ttctttcaat tcgtctaatg ttgatacttc gtcatcaaca tcttttgcga attcgtcatc
    36241 taattcaggc acttcttttg cttttacttc atggattgtc actttgaaga ctgcttcttt
    36301 tccagcaaga tcttctgctt gataatcttc tgggaaagtt acatttacat ctagactttc
    36361 acctgattta tgaccaacta attgatcttc aaaacctgga atgaatgagc ctgaacctaa
    36421 ttcaagtgag taattttcgc cttttccgcc atcaaacgct tcgccatcta caaagccttc
    36481 gaagtcgatt actactgtat cgccattttc agctgcagca tcttctttga taactaattc
    36541 agcttgtgct tcttgttcac gtttgatacg tgcatccacg tcagcatctg ttacttcacg
    36601 gtcttgtttt tcaacaacta gatctttata ttgtcctaat tttacttctg gtttcactgt
    36661 tacttcagca gtgattaccc agtcttgacc tttttccatg ctttcaacat cgatttttgg
    36721 ttgagaaaca ggatcgatgc cagcttcttt gacagcagct tcataagctt ctggtaatac
    36781 agcattcaat gcatcttcat ataaagcttc ttcaccgtac atacggttga atacttgacg
    36841 agaaactttc cctttacgga atccaggtac gttcaagctt tttttcactt tattaaacgc
    36901 agttgttaat cctttttgga tttcgtcttg cgcaatcgta aattttaaaa caccatcatt
    36961 cgtgcctttt ttttcaaatg ttgcagtcat ttaattccct ccgagtttag aaattcattt
    37021 tatacatcaa aaacgtttca tgcatacctt taaatagtac actaaccctt tcaaattgta
    37081 aacatattga atggatagaa tccttgtttt tcataacatt tttatctttt tcactgataa
    37141 aatctaatgg aagaagatca tttgctgcaa aattttttct ctttttttta aaaaatcttg
    37201 tttttcatct tctgtacctt catacatcgt ttttcctgta cacgcctcta cagtcagttg
    37261 aaaccagcgc ttcgggtctt cgatgtatgt atcatagaca ggataaacaa ttgcagattg
    37321 caacgtgaat tcttctttta acacggaact aagcagcgca tcttcattcc cgtaacgatc
    37381 tgaaaataca cataattgct ggtaacttgc ctgctgctgc ggctttggca gatcttttgg
    37441 tatgactttg actaactttt cttcaatcgt caaatagaaa acaggatggc attcgttcaa
    37501 ttgcctaagt gtctccagta attttgccct tgctaaaata tggacctctg gcgatacaat
    37561 aagtttactc gctgtttgga taaactcatg ataaggaagc tgttcgatct catcaataga
    37621 cgcaagctga cgtgcaggtt ccaacgaagg aagttcctcc gatttattgt ggagtgcctt
    37681 gatcttctgc ctctccattt gtccggataa ttcttctgca aattggattt tttcaatgac
    37741 ccgctgctcg aaagcttcat aaaaatctgt acttgctatc aattttctag catataaaaa
    37801 atcttgtgta ctgattaaca agtcaaaata aaattcagca aactcctcat tttgaagata
    37861 ctgtttttca tgcaagagtg cttgcttcaa tgcttctttt ttctcgtcca actcgtaaag
    37921 acaaaaaaca agcaggctat tagcctcaaa gctttctttc aactcgtaag ctcgttgaaa
    37981 taattctttt gcctgctgat attgctggtt tgctagtgct tgttgtgcca ctcgcattaa
    38041 attctcatat ttttctggaa aatcaatcgg cttcacgcag tgtcctcctc ttgctcatat
    38101 tcagctcatg ttcaatagta gcaaaacaaa aaaagcatga caattaaaaa taactgaagc
    38161 accctctaaa agctagattt tagatctgac ttttagaagg tgctttcaac tgttactgct
    38221 ttttattgct catcagctgt tgacttcctg gttgaacgct ttgatcagat tgatcgtaac
    38281 aacacttgta ttagtgaaaa aatcgcccag atgttgcttt ttctgattaa agactgctgg
    38341 aagataccct aacatcagca aaggaaattt tagaatgaac cggcaagcac cttctctaac
    38401 taaaacggtt gaccagctaa gttcttcttc atcaaagctg atgactcgaa taccaaagat
    38461 cattttccca atcgtttggc catgattgaa tttcgtcaat aaaataaaat acgctagata
    38521 aataagtaag gctgtgaatc cgtagagact cagataagaa tctgaaaaat taagccaacc
    38581 tagatttttg gcaataccaa gtgttaaacg cgtaatagct ccgatacaca aaagatcgac
    38641 caagaaggca aacattcgga taaaaaaacc tgcatagaaa tacttaggaa aatcatttgc
    38701 ttttggcggt tcatttcttg tgtccgtata ctttttccat ttacgttgtt tctttttgat
    38761 ttcttcgggc gtcaaaggct ctctttcaaa agagctcagt accttttggg aaaagttgga
    38821 gtcaggtcct acagcaggct gctgttgctt atctttttct tgttccttat tttcatttga
    38881 aagctctgac atgcttactc acctccgtaa taatacattg cttttggtga ttccgctgtc
    38941 cctagattct caagaacgga taagatctga ctagtctcag aaggcttcaa tccctggaat
    39001 tctgctagtt tacttcctaa ccatgtacta gcaaacccag atggcgtgga agaatattct
    39061 actagttccg catcttcaag ctgttgttcc tttcgtatag cttttaaagc atcttcagga
    39121 aatcccaatt catcgactaa acctacttct tttgcttgga caccatcata aatccttcca
    39181 tcagcaattt ttttgacttc ttcttcagat ttattccgtc cctcgctgac gattgctaca
    39241 aaacgactat atgcgctgtc gatatatgct tgaagcaccg cttcttcttc ttttgtctct
    39301 ggtcgcgttc ctgaacccat atctttcaac gctccgcttt taactgttgt atcttccaca
    39361 cccagttttt ctagaagtcc tgaataattc aatcctgaca tgatcacacc aattgagccg
    39421 gtcactgttt cttctgttgc aaagatttta tctgcttgag cagaaatata gtagccaccg
    39481 ctagctgcca tgtttttcat gctgacatac attgggatat catgttcttt acgaatcgta
    39541 tccaatttct tagcgatttc cgcactttcg tagacaccgc caccaggaga atttacttct
    39601 aaaaagatac ctttgactgt tggatcttct tcaatcgcct tcagttgttc cataaaattt
    39661 ttatgattgt aaccttcaga agcaaataaa cctgaagacc ctcccgcagc aatcgttcca
    39721 tctactgata attttacgat tttttgcgta ctgtctccct cttccaacac atttggagct
    39781 agttcttcat ccccatataa ccaactgttc aatccctcaa tttgatcgtt ttcctgaggc
    39841 ttagtcaaac tagctgaaac taacgaaacc acaaataatc ctgcagcaat cagaactgct
    39901 gcccaacgtc ttttattcat tctttctcct ttctaataca agttttttat gacgatcaca
    39961 gtttctgact gctcagaagt gtcgaaccgc tctgcttttt cttcccgcgc atacccggaa
    40021 aacgactctt ttgttaattc atcttctacc gtaaactcac gagcttgagc aacttccaag
    40081 gcatcaggtg cgatttcttg gatgctatcc cagccagtat ctaaaaatat tttcgtatca
    40141 tctgatacac cagctgatgc ttcgaatttg gacaattgtt tttttaacat tcccagtgtc
    40201 atgatctcaa tttttgaatc catttttact cctcctctat ccgattactt tctattgtac
    40261 cgaactcctg aaaaagatga tagataaaaa cccattattt tttgacataa aaaggacatt
    40321 tgacaaagaa tttgatatat accaatttat tttttattct ttttttgttg acaagaacat
    40381 tcgcaaaagg ttatgatttt aaatgtttcc agataaaaaa caaaaaggag gatagttata
    40441 ccttttagga tagcgccagg tctgtgtaaa cagatgacga ggagagggtt tatcgaaaga
    40501 ttcggcggat ggccctaggg actgcactct acagaaaatc cacaaaaaat gtctgcaaag
    40561 ataaaacaaa aggattttcc tgcagctgga agcattcata cgaattcatt atagaaagta
    40621 ggatgttttt tatgtgcgga attgttggaa tgattggatt aaaaaatgta acaccaggat
    40681 tgattgacgg tctagaaaaa ttagaatacc gtggttatga ttcagctggt atctttgtct
    40741 cagatggcac aactgattat ctggtcaaag cacaaggcag aattcaaaat ttgaaaaaca
    40801 aaataaatat tgatactaca ggaaatatag gtattggtca tacacgatgg gcaactcacg
    40861 ggcaaccttc tgaagaaaac gcccatccac atacttccca aagtggacgc ttcgtgctcg
    40921 ttcacaacgg cgtaatcgaa aactttgaag aacttaaaat tgcttattta gcaaatgacc
    40981 actttattgg tgagaccgat actgagatta tcgctcatct aattgaaact ttcgcgaagg
    41041 atactacaac gcaagaggcg tttttaaaag ctttgcgggt catcaaaggt tcttacgctt
    41101 tcgctttgat tgatcggaca gcacctgatg ttatttacgt cgctaaaaat aaaagtccac
    41161 tattaatcgg actcggcgat ggattcaatg tgattgccag cgatgcaatg gctatgcttg
    41221 ctcatacgaa ggaattcgtt gagattgaag atgaagagat ggttaccgtc acatcagaaa
    41281 aagttattat tcaaaatttt gcaggtgaca tcgtagaacg ttcttcattc gaagcacaag
    41341 tagatgcttc agatatcgag aaaggtacct atccttttta tatgctgaaa gaaatcgacg
    41401 aacagcctat tatcatgcgt cgtatcgctc aaaaatacgt aacagaagac aatcgtgtct
    41461 ctcttgatca aaagctggtc gatacattgt ctgatagcga tcgaatctat atcgttgctt
    41521 gcggaactag ttaccatgcg gggttagcag gtaaacagac tttggaaaaa ttgacacaga
    41581 ttcctgttga ggttcattta gccagtgaat ttggctataa cacacctctt ctttcaaaaa
    41641 aaccattctt tattttcttg agtcaaagtg gcgaaacagc agacagccgc caagtgctgg
    41701 taaaaatcaa ccgtctcggc tacccttcac ttacgattac aaatgttgct ggttctactc
    41761 tttcgcggga agcatccttt acactgctat tgcatgctgg acccgaaatc gcagtagcat
    41821 caacgaaagc ttatactgca caaatagctg tactaacttt attagccaaa gctatcggtg
    41881 ataaaaaaga atttgaaact tctcttgtat tcgatatcac tcatgaattg agtttagttg
    41941 ctaatgcgat ggaatcggtc atcgcccaaa aagattattt agaagagttg gcagaagtat
    42001 atctcagcga tacaagaaat gccttttaca ttggacgtgg tgctgactac aacgtttctc
    42061 ttgaagctgc tttgaaattg aaagaaatca gttatatcca ggcagaaggt tttgccgctg
    42121 gcgaattgaa acatggaacg attgctttga tcgaagaagg aacaccagtg atcggaatca
    42181 tcagtgaaga agtgactggt gcgcatactc gaggaaacct gaaagaagtc gaaagccgtg
    42241 gcgctaaaac actagttatt gtctcagagg gattagaaaa ggaaagtgac cagctggtgc
    42301 taccaactgt ccacccttat ctaactactc taaccacagt cgtaccgact caattacttg
    42361 catattacgc aacgctatta cggggattcg acgttgacaa accacgtaat ttagcgaaat
    42421 cagtgacagt agaataataa aagaacaagg accagtgtca gacatctgac actggtcctt
    42481 gttcttttat tttttatgaa aatatctctt aatccagtcc gatttcttct ttgactactg
    42541 ccgcgatttt atcgacatag taattaactt tctcatcagt aggcgcttct gccatcactc
    42601 gaagtaatgg ttctgtaccg gaaggacgaa ctaggattct tccttctgat cccatttcag
    42661 cttctgcctc ttcaatcact tttttgattg ccggaacatc catcgcaccg tttttatcac
    42721 ttacgcggat attcactaat ttttgcggat agattgttac ctctgctgca agctctgata
    42781 atttcttacc tgtctgtttc atgatattca gtaactgaat tcctgaaagc atcccatctc
    42841 cagttgtgtt aaaatctaag aaaatcatgt gcccagactg ctcgccgcca aagttataat
    42901 cgtttttgcg catttcttct acaacgtaac gatcaccaac ttgtgtaacg acatctttca
    42961 aaccgattcc ttccaccgct ttgtggaatc ctaagttact catgacagtc gtaacgatcg
    43021 tatctttttt caatcgattt ttttctgcca agtatttagc acagataaac atgattttat
    43081 caccgtcgac aatgtttcca agttcatcca ccgcaataat acgatcgcca tcgccatcga
    43141 aagctagtcc agcatctgct cctttttcaa cgaccatctc agctaaacgt tctggatggg
    43201 tagagcctac gccgtcattg atatttaacc cgtctggatt tgtgcccatt gtataaaaat
    43261 ctgtttcaag atcggcaaac aaacgattaa cacttgttga agttgctccg tttgctgcat
    43321 cgacacaaat ggtcaaaccg gaaaggtcac cgttgatcgt ttgtacaagg aattgagaat
    43381 atttcaataa gccttctgga aattcttcta cagttcccaa tccttcagct gatggacgag
    43441 gcaattcatc cacttcagca tctaataatg cttcaatttc tagctcttgg tcatctacta
    43501 gtttaaaacc atctgcaccg aaaaatttga ttccattatc ttgtgctgga ttatgagaag
    43561 cagaaatcat gacccctgcg cttgcttttt gcaaacgtgt cagataagca acacctggtg
    43621 tagagatcac acctagctgg aacacttcga tacccaccga taaaagtcct gaaatcagcg
    43681 cttcttctaa catttgacct gagattcttg tatcccgccc tactaacacg cgtgggcgtt
    43741 ttccttcttc ttcatgctgg cttaggacat aacctccgca ccgtcccagc ttaaatgcaa
    43801 gttctggcgt aagttccttg ttggcttcac cgcgtacgcc gtctgttcca aaatatttac
    43861 ccatagttgt aaaattactc ctttaactta attttctgag gaatttgttc tgctcatttg
    43921 tgttgattcg cttgtttctg atgtttcttc tgtacttgtg gtcgagctgc ttgtcccaga
    43981 ttccgaactg gaagaaatgg ttgttgtcga tggttccgtt cctgaatcag cagatgaaat
    44041 acttctactc gtacttgtat tttcttgtgt ccgactgctc gtcgaagcag agctactgct
    44101 tgacgtttgc aacacgggtg taatctccac actaactgat tcgggcttga tacttaaccc
    44161 ctcttctact ggtatttcaa ttttacgagt tgttcgatga ttgatacctg agacattgat
    44221 cggtacagca atactgtcac cgatcgatgc aagcaaatcg ctagagccgc ttacttctgc
    44281 ttccagtttt gaaaaactga aatcatagct ttctaccccg gcagctggtg ttccttgctg
    44341 tatcccataa agtcgtaccg acttgcttgg cttgatcgaa tcagctctca ctgttacttg
    44401 cactggatca gagacgatac ttaatacttc ccctgctgca ttcagcgcct gtattgggac
    44461 ctcactatta atcccatcat ctgtgaccat cgaagcgtcc acatcagcta ctactcgttt
    44521 gatttctgcc aatgttttgt cacctgtagt gatagagact tttttaggac taacggaagt
    44581 atcatcaagt tcatatccag atggtgtgaa cgttgaagga atcaacgttt ccacatcgaa
    44641 atcttttatt acctttttct caaccgttac tgtaatagtc gatggttcga tctttgctgt
    44701 gacagcactg ctcaaatttt gaatttttag cggaacttca tgtgttcctt cgcccagctt
    44761 agtgatatct gctgtgacgc ggaacatccg tgtatcttcg tttgcctctg cattcaactg
    44821 aactcggttt gcactggaaa gtttgacagt cactgcattt tcatatccat ggatatagta
    44881 gcgctttgaa tcataagaaa tcttgatcgg cacccccgta actgtttgat tatacgcttc
    44941 atttccagaa agcgtatttg gaacggactg gccatttgca ttgaagtaca gcgcaatact
    45001 gaacagcaat gcaataaaac tgtaaagaat gcttgtccgt ttctcttttg agatcatttg
    45061 cgatcccctc ccttagtcat accgtctagg aaagattgaa tcacgttttt cttgtttttt
    45121 gttttctctt cagcaattag ttctctacgc aagattgcca aatattcttg ctgggataag
    45181 ccagccatca gttcattatc taacgtgatg ctgacgtccc cggtttcttc agagacaacg
    45241 atggtaatcg cgtcactgac ttcgcttata ccgacagctg cccggtgtcg agtcccgaat
    45301 tctttaggga tcaacatact ttctgataga ggaagatagg cgcttgctac tgcgatcttt
    45361 ccttctttta caataactgc accgtcatgc agcggtgtat taggaataaa gatattgatc
    45421 agcagctccc cagtgatatc tgcatctaaa gcaatccctg tctcaatata ctcatctaat
    45481 ccagtatgac gttcgatagt gatcaacgca ccgatttttc gcttggacat atattggatg
    45541 gctttgtcaa aagacaagat catcttctca tcttcctgct gttcgctttt tgattgtttg
    45601 aaaagcgaac tgcgtccaag atgttccagt cctctccgga tttccggctg aaaaatcacg
    45661 atagcagcta tcaccccgta cgtaatgact tggttcatca gccaagacaa ggtgtgcaga
    45721 ccaatgattt ccgctacgat tcggataaca ataaaaatag ctacaccttt cagaagctga
    45781 atcgcttttg tgcctcgcag cagttggatc agtttgtata caagatacca gacaaccaga
    45841 atatcaagta tgttcaccaa aaaattcaga gagaacaagt caccggaaaa catttgctgc
    45901 caatagtcca aattaaaaag ttccccgatt tgaaatgaca taaaaagcct ctcttctctt
    45961 ttgagatttc ctctctagta tatcatatgt tttaatttta gaggctgata tgctcgtatt
    46021 tttcttgaga aaaacgcata attttcaaga aaattgcaag tatgcgtttt atttttctct
    46081 gcaataaata tttttaaact tcagagaatt attcattata ttttttctgt tatttttcct
    46141 ttttttcttt tgtagcttgt tccatttttt tacgtcgttc tgctctggca gctcttctag
    46201 cagctcttct ttcttctgct tcaaggtccg tcgttttttc ttttctagtc ttaacgggta
    46261 catcgataga ttcctctggt tcaagtcgtt tcttgatttt ttctaattct cccgtcagtg
    46321 cagcatagtt gtaaaaacgt gttttagcgt cgtggacagt cttttcaaat aaagcttttg
    46381 caagatttgg atttgcgtta tctagcgagg aaaagcgaac ttgtttcctc atgaaatcag
    46441 gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat tgggttcttg tttttttcga
    46501 ccattgtagg gttatatcga tataatgacc aataaccaga agaaacagct tcttttgctt
    46561 ctttaagcga ttctttcatt ccgccaagca agccatgtgt gatacaaggc gtataggcaa
    46621 taatcagaga aggaccagga tacttttctg cttcttcaaa tgccttgatc gtttgcattt
    46681 gattggcacc tgaagcaatt tgcgccacat aaacatttcc atatgtcatc gccatcattc
    46741 ctagatcttt ctttgaagca tactttccac tagccgaaaa tttagcgatt gccgaagctg
    46801 gtgttgcttt tgaggtttga ccgccagtat tggaatagac ttcgttatcc aaaacaagga
    46861 tattcacgtc tgctccgctg gcaagtacat gatcgatccc gccaaaacca atgtcgtaag
    46921 cccatccgtc tccaccaatc atccattggc tgttttttac gaatagatcc tttctcttgt
    46981 atatatcctc cagttcaggg aaaattgatc gttcgctttc gatcgcagct tgcagttttg
    47041 ctgctctttg ctgcgttcct tcactctcaa acatgtgtac taaccagtct tccatcaatt
    47101 ctcgtagttc ttctgatact tttggcaata cttctttgat tgaacttgcc aaagcctcgc
    47161 gacgagtctg tgccgctaga agcataccat aaccaaattc agcattatct tccaataaag
    47221 aatttgacca tgcaggccct tgaccacatt cattggtcgt ataaggagaa gcaggagaag
    47281 caccgcccca aatagaagaa cagcctgtcg cattcgcgat catcattcga tcaccgaaca
    47341 tttgtgtcaa taattttaca taaggtgttt cgccacagcc tgagcaagcg cccgagaatt
    47401 caagaagcgg ttgattgaat tgtgtagaca agacagtatt ctttcctttg actggatttg
    47461 ctttttgtct taatgtcatt gcaaaagccc aattcacagc ttgttctttc tgttcttcat
    47521 aaggcttcat cactaaagct ttttcttttg cgggacaagc ctctacacac agaccacaac
    47581 ctgtacagtc ttccactgaa acttggatac ggtattttac gccgtctgcg cctcgcattt
    47641 ctctcacgat aaatccttct ggcgcttctt ccatttcctc ttcatctgct aaaaatggac
    47701 ggatggcagc atgaggacaa acaaaggcac attcattaca catcgtacag cgatcactaa
    47761 tccactcagg tacttctaaa gcgacgcccc gcttttccat agaagccgtt cctaaaggca
    47821 tttcgccagt tgtcattcca tttgctacaa gtgtaccaac agagagttga tttccttcct
    47881 gtgcattcac tggttcaagt atttcttgta tataaccagt gttcctttta ttgatttttt
    47941 caggcatctc caacgttctc caatggtctg ggatcgcgac ttgatgaagc agttcggtcg
    48001 tccgatcgat tgcttgtatg tttttttcta cgatagccat tgatttatgt ccatagcttt
    48061 tcagggcttc ttcttttagc agcggaagca cctcatcaaa aggaatgatg tcagctaatt
    48121 taaaaaaagc cgtttccatt gccgtattga tccggcgtcc caaaccgact tcttgggcca
    48181 atctcatggc attgatcgta tagaatctaa tgttattttc agccaagtaa cgttttaatt
    48241 ttaagggcag atgcgtttct aattgttcgt cgctccaaag agtattcaat aaaaaaatgc
    48301 cacctggctt caatcctttg accaagtcat agctatgcag gtaagctggt gtgtgacagg
    48361 caacaaggtc cgcatgctcg acaagatacg ctgaacgtat cggcgtatct ccaaaacgaa
    48421 gatgagagac agtcagaccg ccagattttt tcgaatcata ataaaaatag ccttgcgcat
    48481 atttatcggt gtgatctcca ataatcttga tagctgattt atttgctcca actgttccgt
    48541 cagatccaaa tccccaaaac ttggcctgga atgtttgcgg ttctgtcaaa ttcagacttt
    48601 cctttggttc caaagattga taagtcacat catccacgat ccctatggta aaccgttttt
    48661 tgcgtatgct tgggtctttt ttcaattcat caaaaactgc tgagatttgg tcgggagtca
    48721 catctttaga ccccaatccg tagcgaccac caataacagc cgggcgaagt tcagaatcat
    48781 ataacgcact ttgaacgtct aataagagag gttctccacc tgcccctggt tctttacttc
    48841 gatcaagaac agcaattgtt tttactgtat gatgcaactt ttgcacgaat gtttccactg
    48901 gaaaaggacg ataaagatgg atattcaaaa aacctgtttt ccgtccgttt gcattcaagt
    48961 aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat agaaacaatg acttcttccg
    49021 catcgtctgc tccgtaataa gtcaccaagt cataagaagt tcctcgtaat cggttgatct
    49081 ctttcatata tttttgaacg atttcaggta atttatcata ataggggttg atcgtttccc
    49141 gttgttgaaa atggatgtct ggattctggt tcgtaccact aacagtcgga tgattgggat
    49201 tcatccctcg tttacgaaat gaagctaatt tctcctgatt gatcagagga gctaattctt
    49261 catattccaa aacttcgatt ttttgaatct cgtgactcgt acggaatcca tcaaagaaat
    49321 tcaaaaaagg gacttctcct tcaatagaag caagatgggc aacaggtgct aaatccatca
    49381 cttcttgtac actgctttca gctaacatag caaatcctgt ttgtcttgca gccatcacgt
    49441 ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac tgcccgacta gcaacgtgga
    49501 aaacacttgg cagtagttcc ccagcaatct tgtacatatt cggtatcatc aaaagcagcc
    49561 cttgtgaagc ggtatatgta gttgtcagtg caccagtttt caatgatcca tggaccacac
    49621 cagctgctcc tgcttcggat tgcatttcta ctacttttac tggttgaccg aatacgtttt
    49681 cttttcctgc tgctgaccat tgatctacta attcagccat ggtcgaactg ggtgttattg
    49741 gatatattgc agcaatctcg gtaaatgcat aagaaatata tgcggctgcc gtattgccat
    49801 ccattgtttt catttttcgc atgattcatc atccttgttc atattctctc ttattatctg
    49861 ttccattata acgtaaaaca tgccattttt ttcttttatt tataaaaata ttttacatgt
    49921 atctatttga attggtcatc taatttttag acaaacagtc taaatcgttg cctttttttg
    49981 tcagacatgt ataaactata agcgaaagag gtgttttaac atggatatat cagtgattga
    50041 tgcaacgaaa acaaatacac aaaaaggaat cctttatggt tcatcgaatg ctcctaaaaa
    50101 aatggtcgaa ttcatcaact tagcttgtcc gtattgccga caatggtttg aagaatctta
    50161 tgagctatta gaagaagcag tccaaagcgg gcaattgcag cgagtgatca aattgttcga
    50221 taaagaaaaa gaaagcttac agcgagggaa cgtgatgcac cggtatctca caatcagcga
    50281 tggccaaaaa gcgatcaaag agatcaaaca aatattcgat actcaagacg agtggaaaca
    50341 tctttctctc caagaagtag cggattttgc agtagataaa ctaaagctga cagaacaaaa
    50401 agacgaacag ctgagccaag ctgtcatcaa cgaagctgag caagcacata ttcgatttgt
    50461 tccaactgtc atcttgggta aagaaatctt tgatgaatct atttcaatag aggaattaaa
    50521 agaattgatc caaacaaaat aaaaaaataa ggagcgtggg acaaaagtaa agaacacttt
    50581 tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt cttatttctt
    50641 ggagttaaac gcttctgtcc cagcctcctt attccgaata aatggtgtcc aaaagcttgc
    50701 atctgccaga ttatctcatt tcttatgaca agctaagcaa attatctcca ccaaataatt
    50761 tattcatatt tttgacttgc gcatactaac taattcttaa attttcatac aaaatttctc
    50821 aatttccctt aacgagtaat atttatgtac ggtgattctc actagtatcc caatcacttt
    50881 ttaagttatc ccgatttcaa ttctacttca aaaatagttg cttttatgta tgctgttagt
    50941 tgattagatg gtcatttgtt gagctaggtc gtttatttta aacaagttgt ttctttagct
    51001 tatacctatc tcgtctacca aacgcaagat ggcaaacaca aatgcatacg catctgtatt
    51061 tgccactttg attcgtataa agctaacaac tattaactcc tctcagctaa tagttgctct
    51121 cttttttatt cagattcatt tttgctgatc acagcctagt atttcaatgg ttttgaacac
    51181 taaaccaaat tgttccatta caacattcac tggctgatga aatggattag tagatttcga
    51241 ttattcaaag cgattttcta ttggtggatc gtgttcccaa ctaataagac ggattccaaa
    51301 cctatcgtac agatcttcta aaccacttat aaattttgca cctatttcag gtgttttatt
    51361 gcgtggatat tctattgtta cgccattaaa tggataccaa ttaggattag gctctctttt
    51421 tttctgtaca tctcccatag aatagttagc actttctggg acataatata ttcttcgacc
    51481 atcctctaat tcatctaata agatatttcg tgatcgtcta tcacttgcta aatgtagacg
    51541 ccacgtgcga taccatgcca tgctacctgc atctgcagaa aatccatcaa ataatgcaac
    51601 aattgtatct tctatcacaa tcctttcccc atctacttca tattctaatc taaaatcaaa
    51661 ctcccctcgg gtaatttctg gtcttggtgg cttaggaccc aatattattc tacttaaaac
    51721 cgcattcgtt cccagatgaa acacagctat aacaacaata atgattaata ttttgtttct
    51781 atttgataaa tttctcatta ttcgcacatc acctctacat tctcacatat tagttcgtaa
    51841 tactccttta atatcaaaat atctactggt cgtaataata ttcgctatga attcctacta
    51901 ctcgtataag aaaggccaaa tcatcagctt ttacttgctg atgatttggc ttgtttctat
    51961 ttatcgtaat tgttttctaa tcaccaaaat tgttaacaat cggttcagat atttcccagt
    52021 tgattaaggt aattccgtat tgtgtcaaaa cttcttgcgc ttctccgaaa ttaagtacag
    52081 ttcttatgta tccactttct cctaatataa agtctacctc tcttttaaaa ccttcctcga
    52141 gatttctaag ggctatatgt ggttttaatg acattgattg tacattttcc cccatataat
    52201 attgcgcact tcctcgacta aaatagattc ctagatc
//
LOCUS       DAXLPC010000006        51177 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.006, whole genome shotgun sequence.
ACCESSION   DAXLPC010000006 DAXLPC010000000
VERSION     DAXLPC010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.006"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            290..1135
                     /locus_tag="ACF3UE_000369"
     CDS             290..1135
                     /locus_tag="ACF3UE_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3633830.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="ACF3UE_000370"
     CDS             1416..2636
                     /locus_tag="ACF3UE_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFD3633831.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="ACF3UE_000371"
     CDS             2633..5353
                     /locus_tag="ACF3UE_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3633832.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="ACF3UE_000372"
     CDS             5337..6281
                     /locus_tag="ACF3UE_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD3633833.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6350..7360)
                     /locus_tag="ACF3UE_000373"
     CDS             complement(6350..7360)
                     /locus_tag="ACF3UE_000373"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3633834.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7540..7884)
                     /locus_tag="ACF3UE_000374"
     CDS             complement(7540..7884)
                     /locus_tag="ACF3UE_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFD3633835.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7877..8311)
                     /locus_tag="ACF3UE_000375"
     CDS             complement(7877..8311)
                     /locus_tag="ACF3UE_000375"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFD3633836.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8449..9186
                     /locus_tag="ACF3UE_000376"
     CDS             8449..9186
                     /locus_tag="ACF3UE_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3633837.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9179..10390
                     /locus_tag="ACF3UE_000377"
     CDS             9179..10390
                     /locus_tag="ACF3UE_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3633838.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10594..11376
                     /locus_tag="ACF3UE_000378"
     CDS             10594..11376
                     /locus_tag="ACF3UE_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFD3633839.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11446..12108
                     /gene="trmB"
                     /locus_tag="ACF3UE_000379"
     CDS             11446..12108
                     /gene="trmB"
                     /locus_tag="ACF3UE_000379"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFD3633840.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12206..13960)
                     /gene="ade"
                     /locus_tag="ACF3UE_000380"
     CDS             complement(12206..13960)
                     /gene="ade"
                     /locus_tag="ACF3UE_000380"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFD3633841.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14092..15021
                     /gene="comGA"
                     /locus_tag="ACF3UE_000381"
     CDS             14092..15021
                     /gene="comGA"
                     /locus_tag="ACF3UE_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFD3633842.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14978..16027
                     /gene="comGB"
                     /locus_tag="ACF3UE_000382"
     CDS             14978..16027
                     /gene="comGB"
                     /locus_tag="ACF3UE_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFD3633843.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16024..16302
                     /gene="comGC"
                     /locus_tag="ACF3UE_000383"
     CDS             16024..16302
                     /gene="comGC"
                     /locus_tag="ACF3UE_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFD3633844.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16277..16747
                     /gene="comGD"
                     /locus_tag="ACF3UE_000384"
     CDS             16277..16747
                     /gene="comGD"
                     /locus_tag="ACF3UE_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFD3633845.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16719..17066
                     /locus_tag="ACF3UE_000385"
     CDS             16719..17066
                     /locus_tag="ACF3UE_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633846.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            17029..17454
                     /gene="comGF"
                     /locus_tag="ACF3UE_000386"
     CDS             17029..17454
                     /gene="comGF"
                     /locus_tag="ACF3UE_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFD3633847.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            17426..17785
                     /gene="comGG"
                     /locus_tag="ACF3UE_000387"
     CDS             17426..17785
                     /gene="comGG"
                     /locus_tag="ACF3UE_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFD3633848.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17957..18964
                     /locus_tag="ACF3UE_000388"
     CDS             17957..18964
                     /locus_tag="ACF3UE_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3633849.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18989..20173
                     /locus_tag="ACF3UE_000389"
     CDS             18989..20173
                     /locus_tag="ACF3UE_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFD3633850.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20610..22193)
                     /gene="abc-f"
                     /locus_tag="ACF3UE_000390"
     CDS             complement(20610..22193)
                     /gene="abc-f"
                     /locus_tag="ACF3UE_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFD3633851.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22298..22426)
                     /locus_tag="ACF3UE_000391"
     CDS             complement(22298..22426)
                     /locus_tag="ACF3UE_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633852.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(22771..22914)
                     /locus_tag="ACF3UE_000392"
     CDS             complement(22771..22914)
                     /locus_tag="ACF3UE_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFD3633853.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23136..23615)
                     /locus_tag="ACF3UE_000393"
     CDS             complement(23136..23615)
                     /locus_tag="ACF3UE_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFD3633854.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23688..23972)
                     /locus_tag="ACF3UE_000394"
     CDS             complement(23688..23972)
                     /locus_tag="ACF3UE_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633855.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24050..24244)
                     /gene="ssrS"
                     /locus_tag="ACF3UE_000395"
     ncRNA           complement(24050..24244)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACF3UE_000395"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24316..25602)
                     /locus_tag="ACF3UE_000396"
     CDS             complement(24316..25602)
                     /locus_tag="ACF3UE_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFD3633856.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25740..26411
                     /locus_tag="ACF3UE_000397"
     CDS             25740..26411
                     /locus_tag="ACF3UE_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFD3633857.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26377..26865
                     /locus_tag="ACF3UE_000398"
     CDS             26377..26865
                     /locus_tag="ACF3UE_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFD3633858.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26878..27825
                     /gene="prmA"
                     /locus_tag="ACF3UE_000399"
     CDS             26878..27825
                     /gene="prmA"
                     /locus_tag="ACF3UE_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFD3633859.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27826..28590
                     /locus_tag="ACF3UE_000400"
     CDS             27826..28590
                     /locus_tag="ACF3UE_000400"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFD3633860.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28823..31036
                     /locus_tag="ACF3UE_000401"
     CDS             28823..31036
                     /locus_tag="ACF3UE_000401"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFD3633861.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31047..31493
                     /gene="dtd"
                     /locus_tag="ACF3UE_000402"
     CDS             31047..31493
                     /gene="dtd"
                     /locus_tag="ACF3UE_000402"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFD3633862.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31664..32923
                     /locus_tag="ACF3UE_000403"
     CDS             31664..32923
                     /locus_tag="ACF3UE_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFD3633863.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33012..33959)
                     /locus_tag="ACF3UE_000404"
     CDS             complement(33012..33959)
                     /locus_tag="ACF3UE_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFD3633864.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34353..35645
                     /gene="hisS"
                     /locus_tag="ACF3UE_000405"
     CDS             34353..35645
                     /gene="hisS"
                     /locus_tag="ACF3UE_000405"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFD3633865.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35660..37429
                     /gene="aspS"
                     /locus_tag="ACF3UE_000406"
     CDS             35660..37429
                     /gene="aspS"
                     /locus_tag="ACF3UE_000406"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFD3633866.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37538..38413
                     /locus_tag="ACF3UE_000407"
     CDS             37538..38413
                     /locus_tag="ACF3UE_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3633867.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38679..40562
                     /locus_tag="ACF3UE_000408"
     CDS             38679..40562
                     /locus_tag="ACF3UE_000408"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFD3633868.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40637..40921)
                     /locus_tag="ACF3UE_000409"
     CDS             complement(40637..40921)
                     /locus_tag="ACF3UE_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFD3633869.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40911..41645)
                     /locus_tag="ACF3UE_000410"
     CDS             complement(40911..41645)
                     /locus_tag="ACF3UE_000410"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFD3633870.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41774..42397
                     /locus_tag="ACF3UE_000411"
     CDS             41774..42397
                     /locus_tag="ACF3UE_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFD3633871.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42589..43710
                     /locus_tag="ACF3UE_000412"
     CDS             42589..43710
                     /locus_tag="ACF3UE_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFD3633872.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43717..46845
                     /locus_tag="ACF3UE_000413"
     CDS             43717..46845
                     /locus_tag="ACF3UE_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3633873.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46864..50058
                     /locus_tag="ACF3UE_000414"
     CDS             46864..50058
                     /locus_tag="ACF3UE_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFD3633874.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50204..50911)
                     /locus_tag="ACF3UE_000415"
     CDS             complement(50204..50911)
                     /locus_tag="ACF3UE_000415"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3633875.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        16746 a         8942 c        10629 g        14860 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 ttgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgttttcttt tattttgatg
     6361 aatcagttgt ttcttcagtt gaagattctt ttgttgaatc agttgatttt gtgtcagaac
     6421 tctttgttga agctgtagtt tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg
     6481 cactcaacac attttcaaag gcatcatctt tgatttttac atttgcatct tttaattctt
     6541 caccgattac tttagttgtg aatgcattgt cacttagttt agtttcagta gcgatatctt
     6601 ttagttgatc tttgtattta tccatgtcat tgcctttatt ttggtttttc accattttga
     6661 caacgtagta ttctgtcgca taagaagtag gatttgttgt agtaataaca tcggagatct
     6721 caccgtcttt caatttgaaa gctgcttctt ttacttctgc aggaatagtt gttgtcgttg
     6781 agtcgaattt aactttaccg ccatcttctt ttgtctctgt atcagttgat ttgtctttgg
     6841 ctaatttaga gaaatcatct ccatcatccg ctgatttttt cacatctttt gcttcatctt
     6901 cacttgataa tttgatgatt tgtgcttcta cttctggatg gaaagatttc caagcagttt
     6961 tcaaatcgtc atctgtaata tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt
     7021 tacgaatata ttctttataa gtatctttcg tatatccagc agcttctaat tgtgattcaa
     7081 aagtatcacc taatgatttc gcttgtttgt cgtattctgc atccacttgc ttatcggtta
     7141 ctttatcgcc atatttgtta ttgaatactt tataaatgat catccgttgt actaaggatt
     7201 ggttcgatga ttcaagtttt gcttcatcat agaaatcaga tacagtgatc gttccgcctt
     7261 tcatcgttgc gatatcttta ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca
     7321 acgcactagt agctgccaaa ataattgatt tttttttcat taaaatttgc actcctgtaa
     7381 ttagttatta tttttatata ttaactatac catatcccat ttcctttaaa aacgttgtcg
     7441 tggtagtttc aaacaaaatt caaaatttca tcacattcct aggaaatacg caaacttttc
     7501 tcacttatat agttaaatct gttgagaaaa taatcattat tatatttgtt caggatactc
     7561 tggcagatca gcttttagtt tttctacttg ttcattgatt tgtgtgatac gtggttcggc
     7621 ttggaattta aaatcttcga tatctttttt gattgcttct tggaaagcag gaatcacaga
     7681 ttcagctgtt tcttttgttt cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa
     7741 atcatttgtc agagttgttg cttcttccaa ttcttcgatc agtttctttc ttgtttcatt
     7801 cccgctcctg ggcgccaata acagacctcc gacagtgcca gcagcagctc caaataacag
     7861 tcctttgaaa aagtttttaa tcatcgcagg acacctgctt tacgattgtt tcttgaatag
     7921 cttttagttc ttccgatcca taactatctt gatgattgac aaagtgaata gaaaaatcat
     7981 cctctttgct gtagcgaggg actaaatgga tatgtgaatg aaaaacagat tgataggcta
     8041 gttcacggtt gttattcaag atattaagac ctttcatttc tggaaaagct ttttccaatg
     8101 cttgagcaat cttaggcaca cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa
     8161 aaatatctgc tacatgacgt ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga
     8221 tgtctaaaaa agcatagacc ttgtcgtctt catatatttt atagcttggg atttcttgat
     8281 tgatgatttt gcaaaaaata cagttttcca tataaaacat cctttctata aagaataaat
     8341 acttcagctt aactttacca taagttaaag ctattgtaag gaaaaaaaca aaataccgtc
     8401 attttcttcg tggtataata aataaaaata aatggcggag gaaaaagaat gagtttaatt
     8461 atcgatcatg tcacaggggg gtacggacat ctccctgtgt taaaagatat cagtttcgat
     8521 gtacagcctg gagagatagt agggttgatt ggactgaacg gagcagggaa aagtacgacc
     8581 atcaagcaca ttatcggtct gctggaagct tcaaaaggaa cgatagaaat caatcatcta
     8641 tccttaaaga aaaatacgga agaatatcgc aaacaaattg ggtatattcc agagactcct
     8701 tctttatatg aagaattgac attgagagaa catatcgaag tcactgcgat ggcctacgat
     8761 atacctatgg atatagcaat gaaaagagca gaaaagttgt tggagacttt tcggttatct
     8821 aatcgtcttg actggttccc agctaatttt tcaaagggaa tgaaacagaa agtgatgatc
     8881 ttatgcgcct ttttgatcga gccttcttta tatatcatcg acgaaccatt tttaggcttg
     8941 gatccactag ctatcaatgc attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc
     9001 ggtattttga tgtctacgca tattttagct actgcagaaa aatattgtga tcgttttgtg
     9061 gtcttacata acggagagat acgagcagac ggttctcttg agatgttgag aaaagaattt
     9121 cagctgccgg attcttcttt ggacgaaatc tatattgctt taacaaagga gcaggcacat
     9181 gagtagtttt tttcaaaaac gtttagcaag acatcaaaag aaaatgatga aatatatgcg
     9241 ttatgtattg aacgatcatt ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt
     9301 atattattct aattggttga aaaccctgca gccaccgttt gcaattggag ggctcataat
     9361 ctctgtattt tggatgctct gtttattcgt gggtaagatg gctacttttg cagaggcagc
     9421 agatattgtt tttttacttc ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt
     9481 tcgctattct tgcatttttc cgttgatctt tttgatattg gcatgcggat tggccatgcc
     9541 attagtggtg gttagtacgg agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt
     9601 atggagtttg aaattcagtc atctgcaaat caagagagca gaattgtttc gactagatca
     9661 acaagttatt cgttattgga aattaggctg gtttttttct tctctgatct ttttgtttct
     9721 atcattttat tggctaatat gggcaggaat agcaggtgca ttagtacagg caagtctata
     9781 ttactggttt ttgtggaagc aacaagaaaa aggattggat tgggagaaaa tggtgcatgt
     9841 agaagaacat aggttgcatc agatctatca atttatcaat ttattcacag atgttcctga
     9901 aattacggca aagatcaaaa gaagacgcta tttggatcct atattgactc atattaaaag
     9961 agaatcaaaa aacacttatc tttacttgtt tgcaagaaga ttggcaagag gttctgattt
    10021 tagtggtctt tatttccgat tagtaattat aggtgggtta ttgattgccg gagtagtcga
    10081 cttttatttt agtctgatta tcggtttctt atttttatat ttgatcggtt tccaactgtt
    10141 acctttagcg aaccagttcc gctatatggt tctcgttcag ctttatccaa tccataagaa
    10201 tcagaagaag caggcgattc agtatctact cacatgggta ttaattatcg cgtcggttat
    10261 ttttggtttg attgctgcag tcgtattaga tgggcagcag cgatgggttc cgctagcggc
    10321 ttatttgatt gttactatgc tctttgttaa actatatgta ccaactcgtt tgaagaagat
    10381 gtcagactga aaacaaagct gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca
    10441 gtaagaatgc tgttcgttct attttttttg agaaaagctg gttttttgaa tggcaattaa
    10501 atgaaaaaga acgtatatgt gcttgacgtg tagtgttcag gcgactagaa taataagtac
    10561 tgcaaaacaa agagtaagag gacgggagaa tgcatgatgg agtttcagtt agaccaagag
    10621 tggcggttac gtcccatcaa aggcgacaca ggaaaaacat acataggcat gcgtgatgag
    10681 gacaaagtct ttattaaacg aaacacgact ccgatgttgg ctgctctttc aagggaagga
    10741 attacaccaa aacttgtttg gacaaaacga acggggaatg gcgatacttt gacagcacaa
    10801 gagtggctgg aaggtcgctt gctgactcct aatgagattg gtcaaagaaa cgacgtgatt
    10861 gatgttttgt accatttaca tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt
    10921 ggtcgtgtca tgacgccgga gaagatgctg caaaaatatg aaaaagaatt accggaagaa
    10981 ctccagaaaa atcaatttct gcaaattgtc catcgttttc ttcgtgagca gatcccgtca
    11041 atagataagg aaaacttatc agtagtacac ggagatgtaa accatcgtaa ttggttagta
    11101 tgtaaaaatt atttatatct agtcgattgg gattcaatca tgtttgcaga ccctgcggtg
    11161 gatattgcaa cgattttagg aaattatgtg ccactgtcta gctggaatca gtggctgatc
    11221 agttatggca tacgcccgac tgacgaaatg cttgaaaaat ttcattggta tgcggccatg
    11281 aatttgctcc aagaaatcac cagatattgc aaacgtgaag atcatcgacg gatgaacgaa
    11341 gaaattttac aattaaaacg aattttcagt ggctgaggtt tggcccaaac tctgcggaga
    11401 tttggccaga cctttttaat tagaggaaag gaatggagat aaataatgcg tgtccgaaat
    11461 cgtccgggag cagcggaaat gttagcggct cacccgaatt ttgtaattag tgatccaaca
    11521 ttgtggaagg gaaaatggaa tgaattgttt gaaaacgatc atccaatcca cattgagatt
    11581 ggtatgggga aaggccagtt catcactgga atggcaaaag cccatcctga aatcaattat
    11641 attggagtag aaatgcaggt cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa
    11701 ccgcttccta acctgaaact tctacatgtg gatggatcag cgttgacaga gtatttcgct
    11761 gacagcgaag tagatcaaat ctatctgaat ttttccgatc catggccaaa aaaacgtcat
    11821 gaaaaacggc gattgacata taagactttt cttgctgtag atgaacagat tcttcgtcca
    11881 aatggagaaa tccatttcaa aacagataat caaggattgt ttgagtattc tctggcaagt
    11941 ttttctcaat atggcatgat cctcaaacag gtatggttag atttacatca aagtcaattt
    12001 gaaggcaata ttatgacgga gtatgaagaa aaattttctt caaaaggtca acgtatttat
    12061 cgagtagaag ctcaatttca agataagacc aaaaagaaaa gtctgtgaaa ctaactttct
    12121 gctttcataa aaacattaat atccataaat aaatctcaga aaatgaacat tacagatgta
    12181 atgtattttc tgggatttat ttgatttaaa atgtatttat ttcatcggtt tttccacaag
    12241 gtggaatcaa ttggaagcga gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg
    12301 gtatgacaga taatgttaag aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc
    12361 ctagttgatg tgctttagtt attaattcat tcaactgttc atagacgatc gaaaaaggtt
    12421 cctgtgtcat gattccgcct ataggaagag aaacacaagc tatttcctgc tgtttgttga
    12481 caacggtcat cccgccacct ttttgaatca aaagattagc agcatacagc atatcctcgt
    12541 cgtttgtccc aacgacaact agattatgcg agtcatgggc aatcgttgtc gctatcgctc
    12601 cttgtttcag ctgaaatcct ttcactatgc ctaatccaat gtttcccgtt tgatggtgac
    12661 gctcgatcac cgcaatcttt aattggtctt tttcgattga aggaatgaat cgttcgcctt
    12721 gtcggtccac tttttctacc aaatctttag tcactagact attcgggata atttcgatca
    12781 catgggcttg tgaagaagaa agaagcagct ctaacgaatg tggatttaat ggttgagcgt
    12841 ttagttttgg cagacaacac gtatatgaat ttgaatgatc agcaaataaa tggtcttgga
    12901 gttgcccaga ttgaacaact aatgttccct tatagaaaac ttcatgaatt ggcagcttgg
    12961 taagatcgtc tgttaagaag aaatcagctt gatacccagg ggcaatcgca cctagtgttt
    13021 tcaaatcaaa acattctgct gcattcaatg ttgccatctg aatggcttgt aatggatcga
    13081 ttccaagtgc aatagcttga cggacgatat gatcgattga tccttctttt actaaatcat
    13141 tgatcagttt atcatcggtg acaaagaagc atcttcttga attttcaggt gtgatcgccg
    13201 gtagtagcga tgccagatct tttgcaacgg tcccttctcg aaccattaaa tacataccaa
    13261 gatccaaacg ttctttagct tcttttgcag ttgtagcttc atgatccgtc cgaatacctg
    13321 ctgcaggata aacatttaac tcttccatgc cgataccagc tgcatgcccg tcaatttttt
    13381 tcttatgctg gtgcatcaat tggatctttt ctaggatgtc tgtttcatta tttgctactg
    13441 cttgatagtt catgacttca gctaagccta aaacttcggg tttttgtaaa aaaggggcta
    13501 atttttttgc atttaaattt gcaccattgg tctcaaaagg ggttacaggt acacaagaag
    13561 gtagcataaa aaagatattc atgagtgttt gtcttgcatc ttctatcata aactcaagac
    13621 ctgtactccc agcaatgttt cctatttcat ggggatctgt cactacagta gtaactccat
    13681 gaagcaagga tacttttgaa aattcgcttg gtgataaaag tgagctttcg atatgcacat
    13741 ggccatcgat gaatcctggc actagatatt gcccattagc attatgtacg ctttttcctt
    13801 cgtattcacc gattcctacg atcattcctt cgcagattgc tacatctttt tccatgattt
    13861 ctttcgtaaa gacgttgacg atcttagcat gcttgatcac taggtcagca ggcttttttt
    13921 tacttgctac ttcgatatat ttccttaatg ttgtttccaa tggagtgcct cccaagataa
    13981 atttttataa gtataacata aattcggctt ttgccaatat ttttttgtaa attcatttta
    14041 tttgaaacaa aaagatcaaa aagacgtatg ttttttgtgg aggggagaat aatggaaata
    14101 aaacgattat cggatcaaat gataagtgaa agttttgcca aacatgccca agacgtatat
    14161 atattgccag cttcagaagt attttacatc tattttcgct atggaaaaaa acgaacattc
    14221 tggaagaaag tctcttcggc agatggacag caactgatct caagatttaa gtatttggga
    14281 cagatggata tcggagaaaa aagaaaagct cagttaggtg catttactta ttctttagaa
    14341 aaacaggaag ttcgtctgcg gttgtcttct gtaggagatt accttcaacg agagagttta
    14401 gtgattcggc tattatacgg tacttttgaa acaccccatc gttgctttag ttctcgagat
    14461 tttgcaacta ttttacagaa aaccgtcaga cgtggattat accttttcag cggaccagtc
    14521 ggatcaggca agacttctct aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt
    14581 actatcgaag atcctgtaga gatagaagaa ccgttttttc tgcagctaca gatcaatccg
    14641 aaaatagcac agacttatga tacacttttg aaactcgcat tacggcatcg tccagacttg
    14701 ctaatcattg gcgagataag agatgaatca actgcacatg ctgcggtaag agcagcacta
    14761 acagggcacc gggtttttgc aaccgtacat gcacgcaatc ttgaaggtac attggtcaga
    14821 atccatgaac tgacaaagaa aaaagaagag ctatctgaat gtttagctgg tgtcatttat
    14881 caagaacttt tggaagatgc caatcaccat ccttctgttt tatggagtta tcaatttatg
    14941 gaggaagaat cagtaaaaaa atcatgggag gaaagttatg aagaagctca ggaaaatatt
    15001 tggcagtcag aactattcta aaggattaac aagaagccag caaaaccagt ttgcacaaac
    15061 catgggagaa ctgcttttat ctggttttag tctgcaagaa tccctttatt tattactcac
    15121 gatccgttcg tttccacctg ttattttggc aaatatccaa catcagctaa aggaagggca
    15181 agcgtttagt gaggtacttt cgcaaatagg atatggagca gagcaactgg tacagatcga
    15241 gttagctgaa cgtcatggga atctgccgac aactttgttg gaaattgcca aacagtttcg
    15301 gcttgttgaa ggatttcgca atgatttgaa aaagctgctt gcatatccga tgctattgct
    15361 cacctttttg ctaggtatct tgtttagtat gcggttgttc gttttgcctc agcttattgg
    15421 ttcaggaatg gtcatgcaag agcattgggg tattcagctg atacaagtct ttcattggta
    15481 tgttctacta ttcatcctag cggttactct attggcttta ctagtaaggt atcgtctgat
    15541 gaagttgtct cctgttgatc agagtgaatg gataagcaga caattattga ttggaccgat
    15601 atattccttg tatcaatcgg cttatttgtc actagagatt ggaaagcttt ttcatgaagg
    15661 tttcgaatta aggcaaatca tagtctgctt aaaggaaacg aaacaagaaa gtctgattca
    15721 gcatcttgcc tctaagttga ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt
    15781 ccagaattat cgttttctat cagaagaatt cagtaaaatt gttttacagg gagaggcaaa
    15841 gggaagttta ggtaaagaac tgatttttta cagcgaatgg acaagaaaac agcttttcaa
    15901 acgtcttcat cactggatgc attttattca gccaatcatt tttttgggcg tagcggcttt
    15961 gattttatta gtttatgccg ctgttttatt acctgtttac ggaagcatag aggaggtttt
    16021 gccatgaaaa agagaaaaat atcttattat agcggtttta cattgatcga aatgctaatc
    16081 gtcttactga tcatcagtgt attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg
    16141 aatcatgtag accaagaaag tcgtgaagcg atcatccagt tggtagacac acaaaaagag
    16201 ctctatgcgc ttcaaaataa tggaagagtt cctactgtgg aggaattgtt gaatgaaggc
    16261 tatatcaaac gagaacatgc agaaatctat cagcggcctt gaaggtaagg ttttagcatc
    16321 aggatatacg ttgtttgaat cactcttact gattttatta cttacaacga tcctttcttt
    16381 tccagttctc gcattttctg catggaagaa tgaattggca gtctatcaat ttttcggcca
    16441 atttgaaaaa cgaatctatt ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg
    16501 cttttattgg aatagtgaag agaatcaaat catttttcat gttccgaatc cagataaaat
    16561 aaattgggaa gtattagata ttcctgatga gattaccttg aaacgccatg cttctattac
    16621 ttttgctgct agaaccggga atgaaagttc actaaaagct tatcaatttt attgggaaga
    16681 aaaagagcgg acgattacgt atcaattcca gatagggagt ggtcgctata caaaaagaat
    16741 tgaataaaac aggatttgtt ttgttggagt cccttacagc gcttatgatc gcttctgtct
    16801 gtgtctactt agtgagcttt ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg
    16861 aggaactgct atttattcga atgatttatg aagatatcaa gacgcagcgg atgtatcaca
    16921 aaagaccaga gcgaagggaa gaaatgatcc catacgatat ccaaattgtc gataataatg
    16981 gagtaatcga aaaagtgttt gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa
    17041 gtaattccag catttacgct gattgaatgt ctaattggac tgatgatatt gagcagtcta
    17101 ttgctcacat tcaatctttt gattcagcaa accatccaag taagtgaatt tttgcagcgt
    17161 aaagatcaaa aagagtggct aatattttta gcacaattag aagaagaact caagagcagt
    17221 cacaatgtct ctgtgaaaaa tcagcaactg cactacacga tcgaggataa acagtatatc
    17281 atcgaaagat atcaggcaat gatacgtaaa agaagaactt ccggcggaca tcaacctatg
    17341 ttaacaagta tcactgagct tcaattattg gaaaaagaac acacaatttc tttttatgta
    17401 cactttgaaa atggagaaga tggatatgcc atatggacaa aaaacgatca gtagaaaatg
    17461 ttataagggc tctattttat tttctgtctt gcttttattt cttttatgta cgtttttatt
    17521 gatggcagca ttagaaagct accgtttgtc aatggatctt aatatacgaa tcaaaaatta
    17581 ttatatagca aaaataatga agcagatggc tttatcggaa cagtctacgc ttgccgaaag
    17641 ttcggaagga gttttttact acacaactgg atctgtaaca tatcagtggg tacaacagtc
    17701 cctattctta gaggtggaag tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa
    17761 tgatacagat actagtacag aatgatggaa tgttcgtgaa aacgccctct tttctgttat
    17821 aacactgttt ttaataaaaa aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat
    17881 tgaaattttg tcaattgttc gatagaatta aacaggtgaa aaaattgtta taatatatct
    17941 agaaatgagg tgcaccatgt taccagaaaa aatggaacaa gggtttaatc aaaacctgga
    18001 agctattcag cttttacaga atgcattggg aacttccttt ttagaagcct atgtcgaaaa
    18061 tgcagaaaat ttaatagatg attatcaagt acgtgtggtg gatggagtgc cgacaaaaga
    18121 gacaacgcaa cggatcacag ctctttatga agagttgaag aaactttctt tcgagccaga
    18181 agaatggcgc agactgtctc aattactttt attgaagggc agccagacag aacatttgca
    18241 ggcgaaccat caactcactc ctgatagtat cggtttttta tttgtttttc ttattgaaca
    18301 actatacaca aataaaaaag caccggttaa gattctggat attgcggcag gaatgggcaa
    18361 cttgttatta acagttcttt taaacctatc gaatgcgggg taccaaacag aaggaattgg
    18421 tgtggatatt gatgatacat tgttggctgt cgcagcttct acaagtgatt tgacacaagc
    18481 aaatgttcaa tactttcatc aagacgggtt gcaggaatta ttaatagatc ctgtcgattt
    18541 tgcaatcagc gatttgccaa tcggttatta tccgaatgac gaaaaagcaa aagagttttt
    18601 aacaagtacc gaagaaggcc atagttatgc acatcattta ttgctagagc aatcaatgaa
    18661 atatgtgaag ccggatggtt ttggtttgtt tttgatgccg agtggatttt tagaaacgga
    18721 tcaaagtgaa gaaatcaaaa aatggtttaa agaagaaggt tatcttcaag gaatgattca
    18781 attgccagat gaattgttcc gtaataaaca atcgcaaaaa agtattttga tcttacagaa
    18841 aaaaggacca caagcacaac aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa
    18901 agaaccagag aaggtgacgg aatttttcaa cgagtttaaa aactggaaat catctgctct
    18961 gtaatcattc aacgagaagg agagtcatat gtctaaaaca attgcaatca atgctgggag
    19021 ttcaagtttg aaatggcaat tatatcaaat gccagaagaa accgtagttg cgaaagggat
    19081 cgtcgaacgt atcggtttac aagattctat ttttaccatc aagtacggcg ataatcaaaa
    19141 attcgaacaa atcatggata tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca
    19201 gttgattgaa ctgcaaattt taagctctta tgatgaaatc accggagtag ggcaccgtgt
    19261 tgttcacgga ggagaaactt atggggattc agtagtgatc gatgagaaag taatggaccg
    19321 cattgctgaa ttagcagaat ttgctccttt gcataatcct gcaaacttaa tggggatcaa
    19381 agcgtttaaa aagattttac ctgacatttt gagtgtggct gtattcgata catctttcca
    19441 ctcaacaatg ccaaagcaaa attatttata tagcttaccg gtgtcttatt atgaagattt
    19501 caaagtaaga aaatatggct tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc
    19561 aaaattattg aacaaaccga tcgaagaact aaaaatcatc acttgccact taggaaatgg
    19621 tgtatcgatc acagcagtcg atggaggtaa atccatggat acttctatgg gattcacacc
    19681 attagctggg gtgacaatgg gtacacgttc aggtgatatc gatccagctg ttctcccata
    19741 tttaatggaa aaattagaga ttgatattga tgaaatgatc aatgttttga acaagaaatc
    19801 tggtctgcta ggcctaacag gattgtctag tgatatgcgt gatcttgaaa agaactatga
    19861 aaaagaacat attcgtttag cttatgacat tttcgtggac cgcatccgaa aatacatcgg
    19921 cggttatgtg acaacgatga atggtgttga tgcaattgtc tttactgctg gtatcggcga
    19981 gaatgacgga catgtacgta gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat
    20041 cgatccagcg ttgaatgaat tgcgtggtga agaagtagat atctctacaa aagaatcaaa
    20101 agtaagagta ttagtgatcc caacagatga ggaactaatg attgcccgtg atgtggagcg
    20161 tctgcgcggc taagccaaag cattcgttag gataaaagat gaaacgcatg caagagggaa
    20221 ttcttgcatg tgtttttttt gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc
    20281 cttctttttt acaggatctt cttagggaat tttgcttgga aaagtggtca aaagggaaaa
    20341 gactggcatt ttatttattg attttcagga aaatcccaat attttatttt cattcatctt
    20401 tataagggac attacatatg taaaaagaaa aaacattttt agatcagcct cgtgggctgt
    20461 cgactttatt cttcgcttta tgtttagcta gaaaaccgat ccgaaacatt cattgatcga
    20521 ataataaaaa cttgattttc cacctgtact ttgcctgaat cgtgaaagca caggtatgaa
    20581 aatcaagttt tttgttgcga aaaaacgtcc tagtcaatca gttggccgag cggctggcgg
    20641 ctgatctgct cctgatcaat aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg
    20701 tcatggctga ctgctaggag cgttccttga tagtcttgca gcatttcttc aatttcttct
    20761 cgagcatagc tgtcgaggtg attggttggt tcatccaaaa tcaggacgtt gattttttct
    20821 aaaaagagtt tcagcaacgc caaacggatt ttttcaccac cggataaatc tttgatccgt
    20881 ttacccacat cgctttgata aaagccactt ttggctaatt gccgtcgagc gacttcttcg
    20941 tttccagtca atgtgatggc gtaagccagc aaacggctat cgggatcggc aaactgcagc
    21001 tgctgcggca aataaccgat ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc
    21061 ttttcctcac cgagtaataa tttgagtaag gttgattttc ctgcaccatt gtcgccgatg
    21121 atggctaaat gatctccacg atagactgca aaactgctgt ctttgaatag tacttgatca
    21181 gcgtactgct ggtgcaagtt ttgaatgatg aaaacttctt tgccagattt tccaccatta
    21241 gacaagcttt gcagccgatt tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc
    21301 aggcggcgtt ccagttcttt ggcttttttg aagaaggact cattgtctcc ttcatgtgcc
    21361 cactgacgaa aacgacgaat catgactttc aaccgctgga cttctttttg ctgcagttcg
    21421 taattttttg tcagctcagc caagcgagct tctttcaaga ctcgaaaacg gctgtagttt
    21481 ccgggatact caatcaatgc accttcttcc agttcccatg tttttgtggt gacttgatcg
    21541 agaaattgcc gatcatgaga aacgaccaga accgattttt ttgtattctg taaatagttt
    21601 tccaaccagc gaatactgtt aagatctaaa tgattggtcg gttcatcgag taaaagtaaa
    21661 tcggcatcgg ctgctaaaat tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt
    21721 tctgttaacc gtgcttcctg acggtgtgga atccctaagc cttgcaagat cgctgcaatc
    21781 cggtcttcta atacgtaacc gcctagttct tcaaagcgat gctgcagctc accgtaacgg
    21841 gccagacact tctctaagtt tgtatctggt tctgtcatca atgcttcgta gcgactcatt
    21901 tgctgtttga ggtcctgtat ctcagcggca gaatggagca agtagtggtt gacggtcgct
    21961 tcggaaactg taagttcttg ttcgaccgtc ccgatcttta agcctttttt gcgactgata
    22021 acaccgctgt cgacaccttc tctgccggtc aagatttgta aaaaggttga tttgccagtt
    22081 ccgttgatac cgactaaggc aattttttca ccagcttcaa tttgacagga taaatcctca
    22141 aataatggat tcccgccgat tgttttttta atagaaattg cttgtatgat catgatctct
    22201 ctccttgaga ccactcaaaa aggccatggt tatccctggc ctgtgttatt taaactcaga
    22261 ttatcatgag aaaaatacct tgagatggcc attgatttta cgtgaattca actgttttgg
    22321 acaaacttgt cccgtcaaca gcaactgtaa aaccaattgc atggctaaat gcgatatggt
    22381 atcgttggta attttcatta cttgttattt tagtcatgcg catcatagta ttttccctcc
    22441 ttcgtgtagt tgtcttttcc agtgtacctg aaagtgtcag aaagttcaac tagcgctgac
    22501 atttacttaa tatttatcga tgtgtaattc tgtcagagag ctttttttat ctgactgagg
    22561 gtaatgtctc gtggaccaca tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca
    22621 tatggtgttt gataaaaaac tttgtctaca tgacttcctt ttgccatttg cttaataccg
    22681 ttgcattaaa cagctcttct ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt
    22741 gtggttgcaa tggcaagcgg tagcctttca tcaattcttg aatgatttac cgaatgtagc
    22801 acttgccttc tcgcggtacc cgaacccgaa ataaaatttt agtttggcga taaaatcggt
    22861 atccgccatc gatacttcat attttttcgt atcagattca tcggaaactt ccacattgac
    22921 gaaccaataa gctttggcat gcttaggtcg ttttaaacca caccagggcg actaatcgcc
    22981 ctggtgttca ctttttttat tttacttgaa ctcattgact gttttccctt tattttaaac
    23041 attataaaga ccgatgagtg cttgccgcgt cttttgtttt tatcacggtt ttttgtgcaa
    23101 aaaaacctgc cgatagttgg caggtcgtct acgtgttaag ctttggtgtg gtctttagct
    23161 ggcaattggt tttctaaatc agttcggaca acaagcacat cgcaagctgc gtttctaata
    23221 acatattcag aaacagaacc aataaataaa cgttctacag cattcaatcc tgtggctcct
    23281 aacataatca aatctacttg attatcttct gggatttctc tggcaataat ttgttttggt
    23341 gagccatatt ctacgacaga ggttacatta ttcaagccag ctttcttcgc attgctttca
    23401 taatctgcca atgtttgctt tgccatttca gtagcttgtt ctgcaagcat tccatcaaag
    23461 gatgaaacgg tttggaaaga acgtgtgtca atgacatgtg ctaatagaag ttctccgtta
    23521 tttcggatag ctacattgac cgccttttta aaagctaatt cagcttcatc agaaccatct
    23581 acggcaacca tgattttttt gtattgttgt aacataagca ttcactcctc aagtcaatcg
    23641 tattgtactc ttttattgta gaacacttta gggaaaaaga gaattattta ctgctttggt
    23701 tcagcaattt tttttgcaaa tcggatactg aaggtggcag aaacaataat tacgatcagt
    23761 aaaaagacca aggcaataaa gcgttgattg aaaaaagctg ttaaaatacc cattacgcct
    23821 aaaacagcat atgcagcacc gtaaaattgt aggaatcctt gatttttatc atttttgttg
    23881 atcaatacaa aaaagatatc ctgtttatta aataaataat agctaacgaa taataatact
    23941 aaagtggcga taatcattaa aatcctaatc atgaacaaat cctccaaaat aagcaacaaa
    24001 tagaaaaagc aatttgccaa gagcaaattg ctttattctt taaaagatgg taatctccgt
    24061 taatgccgtt gtttgtcctg tagtattgat cccgcgaatt caagcaggtg ggtcccatgg
    24121 tcgtagcttc gaactaccaa atgataaggc atgttaccag cagtgacaca agacgggtcc
    24181 caagatatca ataaaaatgt tcggtcaaca cacaaagagg acaattcgaa catcacagat
    24241 ttcccacctc tatagtagca tatgaattta aaaagagcaa tgagagagct cgcagaaaca
    24301 gaaccgtttt cttgtctagt tttttggagg atgctttttc cactctttta tacggtaata
    24361 ctgttgaccc agagcctgtt catatttccc tgtatctttt ggctgataat actgagcatt
    24421 cttcagttta tctggtaaat attgctgatt gacccaagcc tgatcaaaat gatgaggata
    24481 ctgataaccc acgccacggt tgagtgattt cgcacctttg taatggctat ctctcaaatg
    24541 atcaggaaca tctccagctt tgccctctcg aatatcagca agtgctgcat ctaatgccat
    24601 gtaggcagaa ttggattttg gcgacaagca aagatcgacg acgacgtctg ctagtgggat
    24661 acgtgcctca ggcaatccca atttttcagc agctaataca gcgttcactg tacgagccgc
    24721 agcagcagga ttacctaaac ctatatcttc ataaccgata accatcagac gccggcaaat
    24781 acttgccaga tcacctgcct caactaaacg ggcgagataa tgaagtgcag catccacatc
    24841 acttccacga atcgattttt gaaaagccga aataacgtca taatgagcat ctccattttt
    24901 gtcatgggta agagcttttc tttggacaca ttcttcaatg atcgacagtg taagatgaat
    24961 ccttccttct ttatctgaag gagtcgatag tgtagccagt tccagcccat tcaatgcact
    25021 ccgcaaatcg ccgttcgttg cacgcgaaag gtgaagaaga gcatcttcgt ctaactggat
    25081 tgcttgttgt ccaaggccgc gttctttatc ccttaaagca tgttcgactg ccaactggat
    25141 gtcttgttct gttaatggtt tgacttcaaa gatctgtgta cggctgcgga tcgctggatt
    25201 gatggtaata taaggattct cagtagtcgc tccgatcaag atgattcggc cactttctaa
    25261 atgaggaagc agaaaatcct gttttgtttt atctaatcgg tgtacttcat ccaataagag
    25321 gatcactgta ccactcattt ttgcttcttc cgctacaact tgtagatcct tttttgaatc
    25381 tgtagcggcg tttagcatgc gaaatgcata attagtagag ccggcgatcg cacttgcgat
    25441 actcgttttt ccagtaccag gaggtccata tagaatcatg gaagagagca tgcgagcatc
    25501 gaccatgcgg cgtatgattt ttccttcccc gactagatgc tgctgaccaa cgacttcatc
    25561 gatcgttcga ggtctcatgc gataagccaa tggctgttgc ataggatttt cctccttctt
    25621 gtttttacgt cccttaatta tatcatattt agcaagatgc ctagaaagaa cagccttctg
    25681 ttgttttgtt ttcatagctt atccaactaa tattgtgtat gataaagtag gtgagaaaaa
    25741 tgacggataa acaaaagata gatgaatttt tttggaataa aacgacgcca gaagtggcac
    25801 gggatttatt ggggatgtat ttggagcatg acacaccaga aggaagatta gctggatata
    25861 ttgtagacgc ggaagcatac ctaggtccag aagacgaggc cgcccatagc tatggtttaa
    25921 gaagaacacc gcgtgtgcgg gcaatgtatg aaaaaccagg tacgatctac ctttacacga
    25981 tgcatactca tcggattttg aacatcatta ctcagccaga agggattcct caaggagtaa
    26041 tgatacgtgc aatcgaaccc gccgcaatga ttgatcaaat gagtaaaaat cgtggcggaa
    26101 aaactggtcc agatatcagc aacggtccgg gaaaattagt ggaagcatta gcaattcctc
    26161 aagaacttta tggtcagtct atagcagata gttcgttacg cttagttttt gagaaaaaaa
    26221 agacaccaaa aaagatcaat gctttgccta gaatcggtat cccaaacaaa ggtgtatgga
    26281 cagaaaagcc gttgcgtttt gttgtgtcgg gaaatcctta tatctcttta caaagaaaaa
    26341 accaaatcga gaaagattgg ggttggagga aagaaaatga aaaagaagga tctattaaca
    26401 tatttagatg aaataattga aaaacaagtg acagactatg atgtagcttt agattgggat
    26461 acaaaaaatc atacgatcga gatcgttgtt cgcttgtttg cagaaaataa agcacaattt
    26521 gagattgatg atgcagaagg gatcgtttcg caagaaccaa ttatcgaatt tgaagacggc
    26581 gtacttcttt ttaatcctca gaaatctgtt tttgatgaac gcaattatct agcagtaatc
    26641 ccttatgaag gaaaaaaagg gttggcaaaa tcagtagctg attctttagt ggaatatcta
    26701 aatgaagtat tagctcaagg gcaaagcgat ttgcttgatt ttttggatga agacgatgac
    26761 gaagctgtat tcgagcttca ctgggataat caacaactag cagaattagt agaagtaaaa
    26821 cagcaaaatg aagcagatac ttatttaccg tacccaagtt attaaggagt gacagatatg
    26881 aaatggaatg aagtaaaagt agaaactgaa agtgaagcag tcgaagcagt tgctaatatt
    26941 ttgatggagg caggggcgag tggtgtcgcg attgaagatt ctttagatgt tgaacatttt
    27001 cagtcggatc aatatggtga gattttagat aaaaatgatt ttacatcgct gaaagaaggc
    27061 gcactagtca tggcttattt tccggaaacg actttcttac cggaaatctt gccttttatc
    27121 aaagatcgta tcacacaatt acctgagttt ggtctagcta ttggaaaaaa taaagtaaca
    27181 gttagtgaag tagaggaaag caactgggca acagcctgga agaaatacta tcatccggtg
    27241 cgtattacgc gaatgctgac ggttgcgcca agctgggaaa actaccagac agaagatcct
    27301 ctagaaaaaa ttatcacact agatcctggt atggcatttg gcacaggcac tcatcccacg
    27361 acttccttga cattgacagc actagaaaca gtcttgcgtg gtggtgaaac attgctagat
    27421 gtgggaactg ggtcgggcgt gctaagtatt gcagcaaaat atcttggtgc aaaagatgtc
    27481 tatgcctttg atttagacga agtagccgtt cgttcggcga aagaaaatat ggatatgaat
    27541 gaaatagcca aagatgtcca tgtatcagct aacgatcttt tgacaggaat cgagattgaa
    27601 agtgatgtaa tcgttgcgaa cattttagca gatatcatct tattgatgat cccagatgct
    27661 tggcgtttac tgaagcaaac aggcacgctg atcgtttcag gaatcattga agagaagaag
    27721 caaatggttc tggatgccat gttagaacaa gggtttatcg tggatcaaat tttccagcaa
    27781 aaagactggt atgcaattat tttgaaaaaa ccagaggtgg aatagatgca gcggtatttt
    27841 ttaaaagaat catatgaatc aaaagactat tttgttttag aaggggaaaa ctatcaccac
    27901 attgtacggg ttatgaggat ggaacccgag gatgaagttt ttttggcatt caatgatcaa
    27961 atagccattg ttgcagaaat cacggagatt actgaagagg ctgtttatct gaaagaaatt
    28021 aaaaaagaag aaaatcaaaa ggaactgcca agttcgatta ccatagcgag tggctatcct
    28081 aaaggggaaa agctggattg gatcgttcag aaatccactg aattaggagc gcaagctttt
    28141 cttggtttcc cggcatcagc ctctgtcgtt aaatgggatg caaaaaaacg tatgaaacga
    28201 caacaacggc ttgaaaagat tgctcaagag gcagcggaac aatcccatcg gcagatcgtg
    28261 ccatcagtag agttattgga aacgaaacaa gatttatttg agcggctaga tgattatgac
    28321 gtggtcttgg ttgcttatga ggaatcagca aagcaaggcg aaaaatcaaa tgcagccaaa
    28381 attcttagtg aaacaaaacc agatagtcga atcttagctg tctttggacc agaaggtgga
    28441 ttatcccgcg atgaagtcga ttattttgta gaacacaaag ggatactttg tggattagga
    28501 ccaagaatcc ttcgtacaga aacagcacct ctttatttat taagtgctgc tagctatcaa
    28561 tgggaattaa tgaatccttc tttcagctaa cgttcttcat taataaaaga gtatcgacag
    28621 aaagaattga aaaaatagtc aacaatttgt ataatagaaa caattattta tacaatggat
    28681 acgaaaaatc gtttgaaaaa gcttttaaaa agcgaacatt tccgtaaaaa aacgtataac
    28741 tgcacggatt ttgggacaat tatcaaacag atatttgtcc cgattcccgt tttaccgaaa
    28801 aaagaaaggg ggatcgattc ctgtgacaaa agaagaaatt ttaacgggac ccggtgtcat
    28861 aaagctcgtt agtcaataca tgggtcccga acatgtagca tttgttgaga aagcatgcga
    28921 atacgcgact gctgcacatg acggacagtt tagaaaatca ggcgaaccct acattattca
    28981 tcctatccaa gtcgcaggta tattagcaga tttaaaaatg gatccccata cagtggctac
    29041 aggcttctta catgatgttg ttgaagatac agaaatcact ttagaagatc tgagagaaga
    29101 atttggcgat gacgttgcta tgttagtgga cggcgtaacc aaattaggga aaataaaata
    29161 taaatcccac gaagagcagc tagcagaaaa ccaccgaaag atgctgctag caatggctca
    29221 agatttacga gttatcatgg tcaaattagc tgatagacta cataacatgc gtacgttgaa
    29281 gcacctgcga gaagataagc aaagaaggat cgctcaggaa actttagaaa tctatgcgcc
    29341 tcttgcacat cgtctaggga tcagccggat caaatgggaa ttagaagata cagcacttcg
    29401 ttatctaaat ccaaaacagt attaccgtat cgtccacttg atgcagacga agagagaaga
    29461 acgtgaaaaa tacgtaagtg gtactgttga agatattcga atagcgacag aagagctggg
    29521 gatttttgca gaaatctatg gacggccaaa acacatttat tcaatctatc gtaaaatgaa
    29581 agatcagaaa aagcagttca acgaaattta tgacttgcta gctattcgag tgatcgtaga
    29641 ttcaatcaag gattgttatg ctgtattagg agcaatccac acaaaatgga aaccaatgcc
    29701 cggcagattt aaggattata ttgccatgcc aaaagctaat atgtaccaat ctttgcatac
    29761 taccgtgatc ggtccggcag gaaatccggt agaaattcaa atccgaacac aggaaatgca
    29821 tgaaatcgct gaattcgggg ttgctgcaca ctgggcctat aaagaaggaa aaaatgaaaa
    29881 agtagaacca gatggtatga cgaaacaatt aagctggttc catgagatac tcgaacttca
    29941 agacgaaagc tatgatgctt ctgaatttat ggaaggcgta aaaggagata tctttagtga
    30001 taaagtctac gtcttcacac caaaaggaga cgttactgag ttaccaaaag gatccggacc
    30061 attggacttt gcatacagta tccatacaga tatcggtaac aaaaccactg gtgcaaaagt
    30121 aaatggcaaa atggtgcagc ttgattacaa attgaaaaac ggagatatca ttgagatcat
    30181 gacttctcca aattcatttg gcccaagtcg cgactggttg aaattagttg ctactagcaa
    30241 agcaagaaat aagatcaaac gtttcttcaa agcccaagat cgagaagaaa atgtgatcaa
    30301 aggccacgaa tccgtggtca aatgtattac agatctagga tttacgccta aagatatttt
    30361 gacgaagaac aaactgcaag aagcactcga tcgttttaat tatcaaacag aagatgatct
    30421 ctatgcagct gtagggtatg gagaagttag ccccttgacg atggccaatc gtctgactga
    30481 aaaagaacgt aaagaacaaa aaatcgagca gcaaaagcaa gaagcagaag aaatcatgaa
    30541 tcagccgaaa aaagaacctg acaaaatgaa agtacgtcat gaaggtggcg ttgtcattca
    30601 aggggtagaa aacttactaa ttcgtatcag tcgctgctgt aatccgattc ctggtgatga
    30661 tatcgttggt tatatcacta aaggcagagg gatatccatt catcgtcgag attgtccgaa
    30721 tgttcagcct gacaaaccaa atgtagcaga acgtttgatt gaagtcgaat gggaagatac
    30781 atcgaataca cgaaaagagt atgatgcaga tttggaaatt tacggctata atcgttcagg
    30841 cttattgaat gatgtacttc aaacagtcaa tgcgctaacg aaaaatctca acagcgttga
    30901 agcacggacg aataaagata aaatggcgac gatccatttg acggttggta tccagaattt
    30961 atcccaccta aagagtatcg tggataaaat caaagcagta cctgatgtct acagtgtacg
    31021 ccggacgaat ggataggagg acagatatga gagcagttgt tcaacgggta agtaaagctg
    31081 ctgtgtcagt cgatcagcaa gaaattggaa aaattggcta cggcctactt gttttattag
    31141 gcattcatga aaccgatacg caaaaagatg tggactatct ggtaaaaaaa attgcacaaa
    31201 tgcgtatttt tgaagatgaa caaggaaaaa tgaatattag tgtagaagat gtgggaggac
    31261 aaattttaag tatctctcaa ttcacactgt ttgcggatac gaaaaaagga aatcgaccaa
    31321 gctttgtgga agccgcacga ccagaaacag ctattccttt atacgaatca ttcaatgaag
    31381 gaatcagaag tcgcggcatc acagtcgcta ccggacaatt cggagcagat atgtcggttt
    31441 ctctcgtcaa tgatggacct gtaacgatca ttattgattc taaaaacaaa taaagtaatc
    31501 tggttttcac tagtaaaaac tatgaaacac gtcgcttaag ttagactgat aaactctaac
    31561 ttaagtggct tttttgtctg caaaaagcgc ttcttttgtc agcagtcgga aaaaaagtta
    31621 agcttaaatt atacaagtta ttttttatag gaggttgctg aagatgaaag aagtaccagt
    31681 agtagatatc aaaatcacag atttaaaaaa attgtatcaa aaaggataca acatgttgga
    31741 ggagttacgc catgaagcgg acgctcccgt cgtcaaagca aagattttca ataaagaagc
    31801 tatcacgatc tacggatcat cagcagcaaa agtattttat gatccaagga atttcaaacg
    31861 aaaaggtgct atgccaaaat tagtattgaa gacacttttt ggtcaaggtg gagtacagac
    31921 tttggatgga gctgctcatc accatcggaa aaatattttt atggatctaa tgacaccgga
    31981 aagaatggaa gattatcatc gtatcttaga taagaatctg acacaagcac ttgaagcaca
    32041 gcatggtcaa tttgaactat ttgatttaag taagatggtt ttctttacat ctatttgcga
    32101 gtgggcaggt atcaatttat cagcgatttc taaagatgag gtcgaaaaat tagcagaata
    32161 tcaaatctct atgatcagcg gaacgtttac ttctccgatt gatcacataa aaggtgtcga
    32221 gaatcgcaaa aaatcagaaa aatgggcgca aggcttgatt gaagaagctc gacaaaatcc
    32281 tgtggctgga aaagaaaatg tggcattata tgcttttgcc aatgccacag atttagatgg
    32341 tcagctttta cctctggaag tggcagctgt tgaattattg aacatcatcc gtccaacggt
    32401 tgctctaact gtgtgggcgg cattgatggg acatgcactt ttcagtagac cagatttgta
    32461 tcagcaatta aaaaatgact tttcgacgtt acaagatccg tttattcaag aaatgagacg
    32521 ctattatcct ttcttcccaa tgctacctgc gatttcgctg aaagaagtag aagtagatgg
    32581 ttatcgtata ccagaaggca gttgggttat tttagattta tatggaacag accatgatga
    32641 acgaacagtt gaagcgccag attcctttat gatcaaacgg tatgtaggga aagcaaaaga
    32701 tatttcctat aaagaagaat atgagatgat tgcacaaggc gggggaaatt ttcgacaaat
    32761 gcatcgctgt gcaggagaat ggatcactct tcatagtcta cgtgtgtttt ccgatcagct
    32821 agtaaataag tttgagttct ctgtacctga acaagattgg acgattccat tcaatcagtt
    32881 tccgacttat ccgaatagcc gagcgctact ttacaagaat tagattagca taaacttatc
    32941 gaaaaaaagg aagatcaaac agtgctgatc ttcctttttt catattacta taaattgata
    33001 aggtcaattg atcaaaatcc acgaaatgct tcatcaatgg tttgataatc ttcattggat
    33061 aaatgcaaat ctaaagcttg gacattgtca gatacttgct ctggacgctt agctccaggt
    33121 ataactacag acactcgtgg attcttcatg taccaagcta aaacaagttg cgcaggagtg
    33181 gcttggtatc ttttagcaat ggggcgaagt acatcgacag cggttaaaat ttctctgaaa
    33241 cgttctcctt ggaaatctgg atttcttttt cgaggatctc cttcaccaaa ttgtttttcc
    33301 tcaccaagtt catattttcc tgtcagcaaa ccggaagcaa gaggaaaata gggaacaaaa
    33361 ctgattttgt ttttttcaag ataagggaat aattcttttt cagcctgccg atggatcaaa
    33421 ctgtatttat cttctactac atcgacatat ccatctgcat tcgcttcttt caattgttct
    33481 aacgtgaagt ttgacacacc gactgctcgg atttttcctg cttcttttaa ttcgtgcaat
    33541 gtagcaactg attcattttt tggtgtgctt tcatccggaa agtggatata aaaaatgtcg
    33601 atgtaatcag tttgcagacg ttttagtgca tcttccaccg attgtttgag aaactcagga
    33661 gaattatcaa atgttcgccc tttatttggt acatgagcag cttttgtagc gatgacgaca
    33721 cgtgagcgat catattcttt ttccttcagt acctcgccaa tcagttcttc ggaacggccg
    33781 tttccgtaag cataagcggt atcgatcaaa ttgatcccgc tattcaaagc tgtacgaact
    33841 acttgttttc ctgtctcatc ttccaaaccg tcaaaaagat tatgtcctcc aacggcattt
    33901 gctcctaatc caagctgttc tgcgtagact tgtgaatgtc cgattcttat ttctgccata
    33961 gctgattcct cctttttgtc tagtctaaaa caaaatacca aaaagctaaa ctaaaacgtt
    34021 tttgtgaggg gaaatagtca gatatctctt gactttgaga ctggttttta gtaggttata
    34081 agtaatatcg aatgtcaatg aaagagcgag taagtttttg aaactttaca agagaggatc
    34141 atcgaggctg aaaatgatct aaagtttcat tagcctaaag acactctgga gatggacgag
    34201 tgaaaagccg tcccgcgtac gagcgttatt cgtaagagga aagagaaatc tttcaaaatt
    34261 aggtggtacc gtgtatgaat ttcattcacc cttgttcatg atgaacaagg gtgatttttt
    34321 tatttacata gctaagaaag ggagagaaaa ctatgagttt ccaaagacca aaaggaacaa
    34381 atgatatttt gccaggcgaa tcagaaaaat ggcagtttgt cgaagaaaca gcacgtttat
    34441 tattcagaga ttatcagtat aatgaaatgc gtacaccgat ttttgaacac tatgaagtga
    34501 tatcccgaag tgtaggggat acaacggata tcgtttcaaa agagatgtat gatttttatg
    34561 acaaagggga acgccatgtg acgcttcgac cagaaggtac agcaccaatc gttcgttctt
    34621 ttgttgagca taaattgttc ggcccagagt atgcgaaacc gttcaaaact ttttatatgg
    34681 gaccaatgtt tcgctacgaa cgccctcaaa aaggacggtt acgtcaattc catcaaatcg
    34741 gagtagaagc atttggatca gaaaaccctg caactgatgt ggagagcatg gtgatggcac
    34801 ttgatttctt caaacagttg gggatcacgc aaatccggct agtcatcaat tcattaggtg
    34861 ataaagaaac gcgtcaagcc tatcgtcaag cattgatcga ctatctttta ccttttgaat
    34921 cagagctgag tgaagactct aaacgccgcc ttcatgaaaa tccattacgc gtattggaca
    34981 gtaaagacaa acgagatcaa aaatttgtgg cagaagctcc atctatctta gattatctaa
    35041 gcgagcctgc tcaaaaacat tttgataccg ttgtttccat gctggatgca ttggctgttc
    35101 cttatgaaat cgacagtaat atggttcgcg gactagatta ttacacacat acgatttttg
    35161 aaatcatgag tgacgcacca aaaatggggg cacaagcaac gatttgcgca ggcggacgtt
    35221 atgacaatct agtggaagaa ctaggtggtc cttcaacacc tggcttcgga tttgcaatgg
    35281 gtatcgagcg attactcttg actatggagg cagaggaagt agttatccct gcatttaatg
    35341 agttggatgc ttacgtggtc gcactcggag acgaaacaaa tatcgaagca ttgaaagtgg
    35401 tccaagcgat tcgaaacttt ggtttttcag ctgaccgcga cttcatgaac cgtaaagcaa
    35461 aagcgcaatt taagacagca gataaagcga atgccaaatt agtattggtg atcggtgaag
    35521 atgagcttgc tagtcaaacg attaatgtca aagcaatggc aagccgaaaa gaaaaaagtt
    35581 ttccattaga agagatatat gaacattttg atgaagtcta tgatgaaatg actttattcg
    35641 agtaggagga aaaaaataaa tggcacaaag aacgatctat tgcggattag tttccgaaca
    35701 acaattagaa caaacagtta cattaaaagg atgggtacaa aaaagacgag accttggggg
    35761 agtaatcttt atcgacctac gtgatcgtga aggaatcgtt caaatcgtct ttaatcctga
    35821 aatcaacaaa gaagcatggg aaatcgcgga taaatgtcgc agtgaatacg tgatcgaagt
    35881 gactggggaa gttagaagac gcggagaaaa tgcagtaaat cctaaaatgg ccactggtga
    35941 attcgaagtg attgcaagtg aaatcgtgat tttgaatcaa gcaaaaaccc cgccatttca
    36001 aattgaagat gatcaagcaa tcagtgacga aatacgtttg aaatatcgtt atttggatct
    36061 gcgtcgtcca aaaatgacta aaaacatcaa attaagaaat gcgacaacaa aagcgattcg
    36121 tcattattta gatgataatg actttctcga tatcgaaaca ccttacctag ggaaatctac
    36181 accagaaggc gcaagagact acctagttcc ttcacgtgtc catgctggac atttctatgc
    36241 gttgccgcaa tctcctcaat tgtttaaaca attgctgatg aatgctggat tcgaccgtta
    36301 ttatcaaatc gttcgttgtt tccgcgatga agatttacgt ggagaccgtc agcctgaatt
    36361 tacgcaagta gatattgaaa caacgttctt aacagcagaa gaaatccaaa cttacacaga
    36421 gggattgatt gcgaaggtaa tgaaagaagt tcgcggtatc gaagtcacat tgccatttcc
    36481 tcgtatgacc tatgatgaag caatggctcg ctacggcagc gacaaaccgg atacacgttt
    36541 tgatatggaa ttgatcgatc taagcgatac agtcaaagaa gtagaattca aagtcttcca
    36601 aatggctctt gaaaacggcg gtgtcgtgaa agcattgaat gctaaaggcg ctgcagatcg
    36661 ctactcacga aaagacatgg atcagttagg tcaatatgta ggacaattcg gagctaaggg
    36721 gcttgcatgg ctgaaagtag aagaagacgg attgaaaggt ccaattgcta aattcatggg
    36781 agaagcaaca gaagcaatca ttaaagcaac agatgcaaaa ccaggtgact tgctgatgtt
    36841 tggcgcagat aaaagtgaaa tcgtcgctgc tgcattaggt gctatccgga cacgtttagg
    36901 aaaagaatta ggactaattg atgaatcgaa attcaatttc ttatgggtaa ctgattggcc
    36961 acaatttgaa ttttcagaag aagaaggtcg atatgtctct gctcaccatc cattcacgat
    37021 gccaaaagaa gaagatatcc cgttattggc tgaagaccct gcaaaagtct atgcagaagc
    37081 ttatgatatc gtcttgaacg gttatgaatt aggcggaggt tctatccgta ttcatactcg
    37141 tgagcttcaa gaaaaagtac tagaaactct aggctttaca aaagaacaaa tggaagaaca
    37201 atttggtttc ttgttaacag ctttagatta cggattccct ccacatggcg gtattgcatt
    37261 aggattggac cgttttgcaa tgttattagc cggagaagat aatattcgtg aagtcattgc
    37321 ctttcctaaa aacggaaaag cagcagatgt gatgagtgat gcaccaagta tggtttcgcc
    37381 tttacaattg ttcgaattga atattgatgt aacgaatata gaagaatagc cgataaaaag
    37441 gtaaaaagga tttgtcgaat acgcttcttt tgacaacctt gatttaattg aaaaacactt
    37501 tataatgaag ccataacata taaagcgggg cttttccatg aaaaaaacat tcgaaaattg
    37561 ggcttatcat gattacacga ccaagctttc ggtatctatc gtttatgcgt tgatcgcatc
    37621 agtcgcattg aatttctttt atcagccagg acatatttat tcaagtggta ttactggtct
    37681 agctcagatt ttgacgactt tgtcaaaatc actgatagga ttcgaagtac cggtatcaac
    37741 aactttgtat ttactgaata tacctttgtt tgtattggcg tggttaaaaa tcgggaagaa
    37801 gtttacaatt ttcactttta tcacagtcac tttgacctcc ctttgtatcc atattttacc
    37861 ggaaacagtc ctatctaccg atccaatcat ctgtgcgttg tttggggggg ctgtgatggg
    37921 actaggtatt gggctagcgt tgagaaacgg cctatcatcg ggcggtctag atatcgtgag
    37981 tatcacgatt cgtaaaaaaa caggaaagtc gattggttct atttcgatct acttcaatgc
    38041 attgatcgtt tttgttgccg gaattctatt tggctggcaa tatatgtttt acagtacgtt
    38101 gtctattttc gtcagtggaa aagtaactga tgtcgtttat actaaacaaa agaagatgca
    38161 ggtaatgatc gtaacgaaac atccagaaaa agtagtaaat gaaatccaaa actgtatgcg
    38221 tagagggatc acgatcatca atgaagcaga aggtgcttat aagcatgata agcagacagt
    38281 attgatgacg atcgttacac gatacgaact gcctctactt agagaagcaa tgaaagcttc
    38341 tgatccacaa gcttttgtaa gtattgcaga aaacgtccag atacttggtc gtttctatga
    38401 ggatggcatt tagatcgagt ttgacaaaaa ttcatgaaat actgctgtag acagacgttc
    38461 gtttgtctgc agtttttttc taccatagta gaatcagcaa agaaaaactg cttttttatt
    38521 tgaaattttc ttaaagttga aaaaaagcat gtttattttt ttaaatttat gggatgatag
    38581 aaaaaaatag tagagaaagg acacgattct acttgctatt ttcacttaat acccgtatat
    38641 tacgaatgaa aaaagtttat gaaaagttgg aatattgaat ggaaaaacaa aaaaggttaa
    38701 aaaacagccg ctacatcact gggtttgatg ggctccgttc attagctgtg gtgggtgtta
    38761 tcttctatca ccttctgcca actagtatga aaggcggcta tttgggcgtt ccgatttttt
    38821 tcgtcgtatc tggttatttg atcacggatc tgctgcggca ggaatgggaa caaaatggaa
    38881 aaatcaatat ttggcaattt tatgtcagaa gaatgaagag actctatccg gcacttgttt
    38941 ttatgcttgt gacagcttcg gcttatatca ctttgtttca gcgagggctg ttaaacaatc
    39001 ttcgaggagt tgtggtcagc agcttactgt atgtcaacaa ctggtggcaa atcaataacg
    39061 gtttatctta tttcgatcga tttgctaatg agtcaccgtt tacgcatatc tggtctttag
    39121 cagtagaagg tcaaaactat ttggtttggc cgatcttgtt tgtattgttg atggtatttg
    39181 ttcgtaaaag aaaatggatc ttttatactg tgttaggtac atccttcctc tccgccatct
    39241 tgatgatgat cttgtataca ccaggaggcg atccaacccg tgtttattac ggtaccgaca
    39301 ctcgtctgtt ttctatatgg ttgggaagtg cgcttgcgtt tgtttggcca agtacgcgtt
    39361 taaagaaaaa catcccgaaa caagcgaaaa atattctgaa tatcgctgga ggaatctcgc
    39421 ttttggcact gattctttgc ttcttctttt tagatgatca ttacaatttc atctattacg
    39481 gaggaatgct cctagtgagt ctgttatgcg tagtgctagt tgcagtgaca gcacaccccg
    39541 gagcaagttt gaatcgatgg ctgacaaatc cagtatttac ttggattggc aaacgaagct
    39601 atggcattta tctgtatcag tttccagtta tgatttttta tgaagcaaag gtgactgata
    39661 ttgccgatca tgttttgttg catactttag tggaaatcac attgattcta atcatcagtg
    39721 aactttctta tcgatatgtg gagcgtccgc tagcacgttt tgattatggt cgtacattcc
    39781 aagtgatgaa aggatggttc agcaaaccga tcatcagtaa gagcaaacca tgggttgttc
    39841 caggcacatt acttgtagca attgcactcg ttggtttcgt tacggcaccg aaaaacgctg
    39901 taacagccga tcaaaaacaa ctgcaggcaa aaatcgctga aagtaaaaaa ttagcagaag
    39961 aaaccagaaa caattcagaa aacaccacta gttcggttga ccaagcgatc cttgataagt
    40021 acgagttgtc caaggcacaa gggaataagg cacaaaaatt agaactaacg gcatttggtg
    40081 attcagttat gttggatgct gcaacggatc tacaagaact ttatccaaaa gtagtggtag
    40141 atggagatgt cggacgacaa ttatatgcca gtgtaccgta cattgaaaaa ttaaaggaac
    40201 aagatttgtt gaaagacact gttctgattg gactaggaac gaatggctca ttctcggaag
    40261 ctcagtttga tagtgtgatg gatgcaatcg gtgatcgaaa agtatactgg gtcaatgtcc
    40321 gagtaccgac gaagcgctgg caaaatgacg tgaatgcgat gcttgaacag atgacgaaaa
    40381 aatacgacaa tatgacgctg attgattggt acagctacag taatgaccat agtgactggt
    40441 tttatgatga tcaagtccat ccaaatcctg aagggatgac acattacatt cacttagtca
    40501 gcgaagcctt gctaggagga agttcaagta cgaacagcag tgagacaaac gtgacagaat
    40561 gatagctaca aaaaacttca ggcaaaaaca tttgtttttg cctgaagttt ttttatattt
    40621 accgtgtttt taacattcat atagattcag gaagcaaaac ggttgagtgt gtctgtaaat
    40681 aacgttcttt ttgttttcgg gtgagttttt tgaatgcagc ttctgctttt gttgcttcgc
    40741 ttcttgaaga aaatacttct gcatggatca tcttaacagg tcttcttttt tgaagacgag
    40801 tatatttagc accagtacca ttgttatgtt cctctaatcg tctagaaaga tcggttgtat
    40861 atccaccata aaatgtctga tctttacaga ataatacgta aaaataatgt tcatttgcca
    40921 tagagcatct cacgaatctc tgcagtgtat tctccatcca tattgtaagt gatcaatggt
    40981 ggagcgactt tgaatccgtc taatttgcct tctttgattc cttcaactaa caaaatattt
    41041 gcctcttttc caggttttgg gtaaacaaat tggatccttt taggtgcaat tcgatagtct
    41101 tccatgacct gaatgatttc taagaaccga tcaggacgat ggaccatagt aaagcgtcca
    41161 tttgttttta gtagcttact tgaaatatcg atcacttctt ctaacgtcgt atgaatctca
    41221 tgacgggcga ttgccaggtg tttattaggg ttcgttttat ttgttggcag ccctttgaaa
    41281 taaggtggat tacagacgac taagtcacaa gaattatgtc gaacgacaga taagctgtct
    41341 ttcagatcga tggtgtggac agtcatttgt tcatttaaat ggttaagcgc gatactacgt
    41401 cttgccatgt ctgctagacg aggttgaagt tcgatagcgt cgatagccgc ctgggttcgt
    41461 ttacttaaaa aaagtccaac tgcgccattt cctgcacaaa ggtcaacaat cttccctttt
    41521 ttaggtacac gggaaaagtg agcaagcagc acagcatcta aagaaaaaga aaacactttg
    41581 gaactttgga taatcttgat atcttctgcg tataattggt cgattcgttc gtcttcgtga
    41641 agcatggatt ccctccaaaa tgaaaaaaat agtcgtctgt attatactat ttttattaaa
    41701 aagaaccaag gtggcttgtc aaacctctat tttttatgca tactatgacc ataagaaggg
    41761 aaaggaagag actatgtttt atcgatttat gcgcggggta gttcgagtac tattagcctt
    41821 agttaatgga aatgcccgct atgagaataa agaagtttta ccgcaagatg agaattacat
    41881 actagttgct ccccatcgta cttggtggga cccattatat ctggcggtag ctgcagcacc
    41941 caaggaattc agctttatgg caaaagaaga actgttcaaa aatccagttc tgcgatttat
    42001 attaactcga tccaatgctt ttccagttaa aagagaaaat ccaggaccaa gcgtcattaa
    42061 aacacctgta aagattttga aatcgacaaa tttgagtttg atcatgtttc ccagtgggac
    42121 aagacatgct acagaactta aaggcggaat ggcattgatt tccagaatgt ctaaagcgaa
    42181 aatcgtgcca gctgtatatc aaggtccgtt gacacttggg gatctgttca agcgtcagag
    42241 agtgacagtg cgtttcggcg aaccaatcga cttatcagat atcaagaaaa cggataaaga
    42301 aggtatggcg gagatcgaac gacgaacaca agcagctttt gacaaattgg acaaagaagt
    42361 gaaccctgat ttcaaatatg aagtcaaaaa aaaataaaat gataagttta tgcgtgggcg
    42421 gtcttttgaa tctactgtcc tgttcagttc agactttttc aatgaaaacg agggagagac
    42481 gtcaagtctg ccctcttttt gcgttccaat atgtaaaata gaagacaggt gtcatgtaat
    42541 ggatcaaagt gttataataa ttagaaggac attttttgag gtgattgaat gcgtttttta
    42601 catacagccg attggcatat cggaaaaaaa ctacaaggtt atgacttgat tgaagaccag
    42661 cgtcatgtac tatcttctat actagatatc gcgaaagaag aaaaagtaga ggcaatcgtg
    42721 attgccggag acttatatga taggagtgtc ccagctgttg atgccgtaga attatacaat
    42781 gaattgatgg tcgattggaa tttaaaggaa aagatcccga tttttgctat atcaggaaat
    42841 cacgatagca gtacgagact ttcagcgggt acgccatggt tcagttattc gaactatttt
    42901 ttgcgaacac agctagcaga agcatttgaa ccagtcgagt ttaaaaacgt acaatttttc
    42961 tttcttcctt actttgaacc aattgcagcg agattatatt ttgaagatga caatatccga
    43021 acgatcaagc aagcggtagc caaggtgata gataaaatgc aggagctatt tgattcagaa
    43081 aaaaaacaag tattgattag ccattttttt gtaatgggaa gtgtaaaatc tgattcggaa
    43141 acgaaaatcg aagtaggcgg gttggattcg atccctggtg aactacttac accgtttgat
    43201 tatgtagcac taggacattt gcataatcaa gctgctttga gacaggataa tgctcgctat
    43261 agcggttccc cattgaaatt ctctttatct gagatcaacc aaaaaaaagg cgtatggatc
    43321 gttgacctga caacaggcct ggagttgaat tttagggaga tcgaacccct gcatgatatt
    43381 gaagaaataa cagcgagttt caaagaattg ctggatcctg ccttttatca gtccgtcaat
    43441 cgggagaatt acatctatat ctatctcact gatagaacga tcatcccgaa tatgatgaac
    43501 cagcttcggc aaatatatcc tcgtattttg gggattgaac gggcaaacgg tcgagcagaa
    43561 caaacaaagc gcaaacgaaa agtactagaa atgaaagatc ctcaaaaatt agcagaagca
    43621 ttttttagtg aaatgacgga agagcagcta actgcaaacc aagaaaaatg gctcggagaa
    43681 acgttgcaag aaatcatgga aatggaatga tcaagaatga aaccgaaaaa attacaactt
    43741 aaaaattttg gtccttttat caatgagacc gtagattttt cacgtttgac agaagcaccg
    43801 ctttttttga tcagcgggaa gacaggagct ggcaaaacga cgatttttga tgggatcacc
    43861 ttcgcacttt ttggtgaaac ttccggaaga cttcgctctg gaaaagagat gcgttctttg
    43921 tttgctacac cagacgaaga aacaagcgtg actttttctt ttgaacatca gcagatgagc
    43981 tatgaaatcg aacgaaaacc agaacaagtt ttagcaaaac gaaaaggaaa cggaacaaaa
    44041 aaacaggcag ccaaagtaac gttgaccatt tttgatggga aaggaaaaga aataaaacaa
    44101 atcacaaaac gtacagaagc agatcagttg atcagagaac tgatgaatct cgatgcgaaa
    44161 cagttttctc aaatcgtttt actaccccaa ggagaattcc gtaatttttt ggtttcatca
    44221 agcagtgata aagagactgt tttacgtcat ttattcggta ctcaattttt ccaacagttc
    44281 aatgagcgat taaaagaaaa agcaaaacaa cagcaacaaa aattggatca tttagagcaa
    44341 gagctgcatc ttctgcaaaa aaggtttgtt ttagtcaaag aagaggaacc agcagcaggg
    44401 tttgaagccg ttttagccca atggacaaac catcaggcaa tactcgaaaa acaaatcacg
    44461 gaagaaaaag aagctctaac ggaacttcag gaaaaacaaa agcaactaga aaattcctac
    44521 tatcgttttg aaagcttgaa aaaaagttat gaagaaaaaa cgatattaat aaacaagcaa
    44581 aaggaattag ctgctcaaaa agacgaaata gaggaaaaga aacgatggat tgggtattat
    44641 gaatttacgc aacgattagt cgaaccaatc cagcgcctac aagaaataaa agttgaaaaa
    44701 atagaactgt cacaaaaaag tagtgagcaa acaaagaaac tagcgatgac tacgcagaat
    44761 tatgaagagt ggcaaaaaaa tgaagcaaac cgcgtacgcc gacaaacaaa aatcaaagaa
    44821 gctgctcaaa aactgcaaaa caaacagatg atggtgccaa ttgtcgaatc cttacgtagt
    44881 aaaaaacaag acgcagaaca attaacaatt tcattggata aagaagaatt gaatgccgag
    44941 aagctgtatc aaaatctcgc tatctatcag gaaagaactc gaattcttca agaaaattta
    45001 ctggatcagg aaaaactgca agaagatcgt cttgcttttg gacagttaaa atatctagat
    45061 gaaaagcagc aagaaataga aaaacaaaaa gcaaaagaca ctgggtcgct cgcacagata
    45121 agagaagaac tcaaaaaagc aactgaagaa ataacaaaaa atagtcagct attgaaagaa
    45181 cagacagaac aagcagaaca gctgaaaagc caatgggcaa agcagcaaat tgctcgtctt
    45241 cagctttttt tgcgtccagg ggagccatgt cttgtttgtg gatcaacgga acaccccata
    45301 caacaattaa aacacgaaca gccaaataag gaagatatct taaaagtaga acaacaactg
    45361 gcagaagctg agtctgctgt agaaagaact cagcaaatca ttgccaaaag tgaagcacat
    45421 gaaaataatc ttcaacaaca attatcagat ttagaacaaa aaatcatggc aacgaatata
    45481 caattggctg aacaagaaga acacttgcaa caggctttga aaaaggcatt tcctgagata
    45541 acagaacaaa aaacaaaaac aactcttgta gtaatcgaac aatctttaga tagacgaaaa
    45601 agcaagatgg ccaatgcaag aatagagctg gaagaaataa gacaacaagc agaaaagctc
    45661 gaacaacaat tagctgtcta caaacagcag cagacagaaa aaaataatca gctccagcaa
    45721 ctgcaaggag aaatcaaaag tttagaacaa caattgcaag atacggatag taactgttta
    45781 gaagaggaga tacgacgact tgaaaaacag ttagaagaag actcgaatca actagctgtt
    45841 gagcagaaag caggagtgca attgttgcaa gatcttcata cgcttcggac acagcttgat
    45901 cttcaacatg aacaaataga aaaaatagat gaaaaaatag aaaaggaaca agaaagaata
    45961 gctaaaaagt tagaaagcca gtcgtatttt tcaacaattg aagaaatctg tgcatttgca
    46021 caacagcaag cacaatataa agaaaaccaa cgtacagtta cttcttatca tgaagagcaa
    46081 ttagtgacag ctgaccggct gcgtcaatta gaaaatatcc agctaactga gacattccca
    46141 gatacagaag agatcagcca acagttagaa gaaataagac gtatgatcga aataaagcaa
    46201 gaaaagatat acggtttaca agaacaaaaa attagtaatc aaaaaatcta cgatgaatgt
    46261 ctttcgattt atcacacaag ccagacgaaa ttagatgagc ttacgcaatt acagcagctt
    46321 tcgcaaacat tcaacggaga aaatcctaag aagactagtt tggaacggta tgtgcttcag
    46381 gtttatcttc aagaagtgtt acaagtagca aatgatcatc tccaacgttt aacgaaaaat
    46441 cgttatcaat ttgagctagc ggataccatt ggcagttatc gagggaaaac cggattagaa
    46501 atcaatatct atgatgatca ggcaggtatg tctcgaagtg cgcataccct gtctggcggt
    46561 gagagtttta ttgcagcact ttctttagca ttagctcttg ccgatgtgat ccagacacaa
    46621 gctggtggtg tagcaatcga tgcattgttt attgatgaag gatttgggtc attagatgaa
    46681 gaagctttgg aaatggcaat ggaagcttta gaaacgatcg aaagtgaagg aagaatgatc
    46741 ggcatcatta gtcatgtaag agaattgaaa gaacgagtat tacaacaaat aagaattgat
    46801 acagaaggta gcggacaaag caaaatacgc tatcaacttg gataaaaagg gagattggta
    46861 actatgaaat ggagtattcc agaaaaagtc attgcacgtg gacgtcaata cttgcaagaa
    46921 ggccgagtgt tatcggttgt ccctgaccaa gaagaaaacg tgtggcatgc agaagtcttg
    46981 ggcagtgaat tgtatatggt tgatttggat ggtacagcaa aagagataga ttactgccaa
    47041 tgtccctatt gggaggaaca taaatattgt aagcatacag ttgctgtgga actttattta
    47101 cggtcgaaaa atctatctcg tatcatgaaa aaagaccagc caatgctaga accggtaaaa
    47161 gcaacaagtg agggagaaat cattgcaaaa ggtttttctc gtctaaaaac acaaaacaat
    47221 cctcaagcgg tgcaaccttt gattattgaa taccaagtag aaacgattga gactaatcag
    47281 tatcacccag agctttctat tttggcactt tacttgcgta tcggttcatt ggcatcaccg
    47341 aaaaaaacat atatcgtaaa aaacatctat gattttttac aagcttacac agaaaaagaa
    47401 acttacactg ttaataaaca gtaccagttt cgtctagata aacgggcgtt tcaaaaagaa
    47461 gatcaaaaaa tactcacgca tcttgcagga agtgctcaga cgcatcaatt attaggtacg
    47521 aacggcttac aagtcaaagg aaaactagat aaaagatatc tgcttctccc agtagaacaa
    47581 gcccgcttcc tgttagagca gatgaatcag actacacgtt tgcatctgca gataaatgaa
    47641 caaaacgatc aaggaataca attttccgat caaaacaaac ctttatcatt caaagtggaa
    47701 aaatttggag aagattattt gctgcaagca ttgaatgatt ttgatttttt ctttatgcat
    47761 tatcagtggg gagttatcca agggacattt tattctctga cgaaatatca acaaacggtt
    47821 tatcaaactt ggaaacaatt gattcgccga ttggagaaac cagaagtagt gttcaagaaa
    47881 aaagaattac cgtctttgtt taaagagatt atccctctgc tgtcagagat cggcgacgta
    47941 gctattgccc ctgcagtaga agaggaagta gcagatatcc ccgtcgaatt tattttcttt
    48001 ttccgaaaag caaaaggaaa aatccaagct cgagtcgatt tcgtctatgg tgaagtcatc
    48061 tattcgactg acccgaagca tgaggtctcg acagaacagg cttttcaggt gttacgtgac
    48121 acagtagaag agaaacgagt acttgatcta ttcagaatgt atcgctacca gaaaaatgaa
    48181 actggttatg aacgtccatt gccaagcggg gaagaactat atgccttttt ccgcacagaa
    48241 ctatctgtct tccgtcagtt tggtgaagtc agacttggaa gaaaattgcg agagttgtat
    48301 ttagatgcgc ataaacatca accgaaaatc gaagtaaccg agaccggttc atggctcgat
    48361 attcgattcg atgtgacagg gatagaggag caagaaatcg atcatgtcct gcaaagcttg
    48421 ctgagaaatg atgcttttta tacattagaa aatggtcagg ttctttcttt tgattcagaa
    48481 gaatttcaac aaacaagcca agtgttgcaa caattacggg aatcgatacg tacagaagaa
    48541 ggaacgatcc atgtacctaa aaatcaagga ttgatcattc aaaatcaatt ggaaaaaagc
    48601 aatgctactt ttagtgaatc gttccaaacg atggtacaag atctcattca tccagaaaga
    48661 taccaggcac agcttcccaa aggattgaat gcaacgatga gagattatca aaagcaaggt
    48721 tttcgatggt tgaagatgtt aggtcattat cagtttggcg gtattttagc cgatgaaatg
    48781 ggacttggga aaacactaca gacaattgcc tttttacttt cggaaaaaga agaacggaaa
    48841 agcttctctg ctttgatcgt agcgcctgcg agcttaattt acaactggca ggcagaggtg
    48901 agaaaattcg ccccttcttt aagtatccaa gtaatcaatg ggaataaaaa agaacgtgaa
    48961 gaattactgg ctaaagacac agatatccga gtgacttctt atgccagctt aagacaggat
    49021 ctagctaatt atcagtcgca aaaaattgat tatttgattc ttgatgaggc acaaatggtc
    49081 aaaaatagca gtacgaaaac tgcacaagca ttgagagaat tagctgtacc tcagcggttt
    49141 gcactgagtg ggacaccaat cgagaataat ttagaagaat tgtggtcatt gtttgcaacg
    49201 attatgccag gatttttccc gactaaaaca aaattcaggg aacttgccgc agaagaaatt
    49261 gcgcaaatga ttcgaccgtt tattttacgg cgagataaac aaactgtgtt gaaagacttg
    49321 ccggaaaaaa cagagatgaa tctatattct gcacttacag aagaacaaaa aactgtttat
    49381 ttagcttact tgcgtcaaat gcgtgaagaa atcacatcaa tggattctga agcattcaag
    49441 aaaaaccgga tcgggatact tgctggtctg acaagactgc gacaaatttg ctgcgatcct
    49501 cgtctgttta ttgaagatta ccaaggcggt tccggcaagc tcgaacaagt aaaagatcta
    49561 ctggtagctg ccaaagagaa caaacgaaga gttttgctgt tttctcaatt tacagggatg
    49621 ctgactatct tgcaagaaga gttagccgag ctagggatct cgacatttta tttaagaggc
    49681 agtacgaaac cacaagatcg gttaagtatg gtagacgcat ttaatgctgg cgaaaaagat
    49741 gtttttctga tttccttaaa ggctggggga actggattga atctcacggg agcagatacg
    49801 gtcatcttgt atgacctttg gtggaatcct gccattgaag aacaagctgc tggacgtgca
    49861 catcggatcg gacaaaaaaa tgtggtagaa gtgtggcgta tgatctctga aggaacgatt
    49921 gaggaacgca tggattcact ccagcaagaa aaacgcgaac tgttccaaaa agtgatccaa
    49981 ggtaatgaag aacagttgac gaaactgact gaagaagaca tccgcatgat tttaagtgta
    50041 ggagaaatcg aggagtaaga gactcgaaaa agcgttcagt aatgggtaag aaagcctttc
    50101 taaagaagcg attgtttatt tgatttaaaa aatagcaagg aggctgggat tccattttat
    50161 cccagcttcc ttgctatcat ttttttattt ctatttttaa aggttataca aagattgtct
    50221 tcattgtctc taacagctga tcaaaagaag aaatctcgat atcgcaaatt ggagtctgtt
    50281 caattttgcg ttctcgatgg ttgaaccaaa gcgcttgcca gttagcactt tttgcaccta
    50341 gaacatcatt gtcgtaatta tcgccaacgt ataaggtctc ttctggaagc atatgaaatt
    50401 ctttctcagc cagctgaaaa atctcttttt ctggtttttg gaaacctgtt gcttgagaaa
    50461 tgagcatatt gcgggaagga atccaattgt tcaattgaag ttgcttcagt ttttttgtct
    50521 gatggtcagt cggcccattt gtgataattc ctaatgggac attcttttcc ttcaagaaat
    50581 cgagggtttt tttgacctcc tcatgcaagc agatattatc aagttcttcc tcgtaaattt
    50641 tttgaaataa gaggccatct tcttccgtaa tatgagggta gtctaaatct tttagtgatt
    50701 ggctgatccg atgtgctcgc atatattcta gtgtccaatc tcctgccatt acttttggga
    50761 agttttcatc actatgatgg cggaaccgga tatatagtgg atgcatatct gcatctgaaa
    50821 caagcggaac gactcttttg accgcgtttc gaaatggctg ctgctgatca tacatcgtat
    50881 catcaacatc aaacacaact gatttaatca aaattttaca cgcctttcgg ttttcattga
    50941 ttttttcaca aatccttgac tattgtaaca gaaaaaattg tctaaaaaag ctgataaata
    51001 aaggtttttc ttactatatt tctatttcct tgacagaata aggtttttat atttcagttt
    51061 ttttcactaa aaatcgtgaa acacgtcaat aagtttgatg aacaaattaa tcattatggt
    51121 agaagtcgat tgatttattt taatgcaatc tctgtggaat tttcgaaaga tttattt
//
LOCUS       DAXLPC010000007        49483 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.007, whole genome shotgun sequence.
ACCESSION   DAXLPC010000007 DAXLPC010000000
VERSION     DAXLPC010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.007"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(271..1998)
                     /locus_tag="ACF3UE_000416"
     CDS             complement(271..1998)
                     /locus_tag="ACF3UE_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFD3633876.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(1991..3184)
                     /locus_tag="ACF3UE_000417"
     CDS             complement(1991..3184)
                     /locus_tag="ACF3UE_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFD3633877.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3371..4015)
                     /locus_tag="ACF3UE_000418"
     CDS             complement(3371..4015)
                     /locus_tag="ACF3UE_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3633878.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4109..4243)
                     /locus_tag="ACF3UE_000419"
     CDS             complement(4109..4243)
                     /locus_tag="ACF3UE_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFD3633879.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4245..6377)
                     /gene="feoB"
                     /locus_tag="ACF3UE_000420"
     CDS             complement(4245..6377)
                     /gene="feoB"
                     /locus_tag="ACF3UE_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFD3633880.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6374..6847)
                     /locus_tag="ACF3UE_000421"
     CDS             complement(6374..6847)
                     /locus_tag="ACF3UE_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFD3633881.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7248..7472
                     /gene="nrdH"
                     /locus_tag="ACF3UE_000422"
     CDS             7248..7472
                     /gene="nrdH"
                     /locus_tag="ACF3UE_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFD3633882.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            7631..9790
                     /gene="nrdE"
                     /locus_tag="ACF3UE_000423"
     CDS             7631..9790
                     /gene="nrdE"
                     /locus_tag="ACF3UE_000423"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFD3633883.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            9840..10805
                     /gene="nrdF"
                     /locus_tag="ACF3UE_000424"
     CDS             9840..10805
                     /gene="nrdF"
                     /locus_tag="ACF3UE_000424"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFD3633884.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(10894..12033)
                     /locus_tag="ACF3UE_000425"
     CDS             complement(10894..12033)
                     /locus_tag="ACF3UE_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3633885.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12342..13055)
                     /locus_tag="ACF3UE_000426"
     CDS             complement(12342..13055)
                     /locus_tag="ACF3UE_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFD3633886.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13309..14010)
                     /gene="nagB"
                     /locus_tag="ACF3UE_000427"
     CDS             complement(13309..14010)
                     /gene="nagB"
                     /locus_tag="ACF3UE_000427"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFD3633887.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14244..15776
                     /locus_tag="ACF3UE_000428"
     CDS             14244..15776
                     /locus_tag="ACF3UE_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD3633888.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(15967..17169)
                     /locus_tag="ACF3UE_000429"
     CDS             complement(15967..17169)
                     /locus_tag="ACF3UE_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3633889.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(17251..17940)
                     /locus_tag="ACF3UE_000430"
     CDS             complement(17251..17940)
                     /locus_tag="ACF3UE_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFD3633890.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(18046..18414)
                     /gene="rplL"
                     /locus_tag="ACF3UE_000431"
     CDS             complement(18046..18414)
                     /gene="rplL"
                     /locus_tag="ACF3UE_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFD3633891.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(18467..18970)
                     /gene="rplJ"
                     /locus_tag="ACF3UE_000432"
     CDS             complement(18467..18970)
                     /gene="rplJ"
                     /locus_tag="ACF3UE_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFD3633892.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(19174..19301)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(19380..20069)
                     /gene="rplA"
                     /locus_tag="ACF3UE_000433"
     CDS             complement(19380..20069)
                     /gene="rplA"
                     /locus_tag="ACF3UE_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFD3633893.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(20173..20595)
                     /gene="rplK"
                     /locus_tag="ACF3UE_000434"
     CDS             complement(20173..20595)
                     /gene="rplK"
                     /locus_tag="ACF3UE_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFD3633894.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            20938..21606
                     /gene="sdaAB"
                     /locus_tag="ACF3UE_000435"
     CDS             20938..21606
                     /gene="sdaAB"
                     /locus_tag="ACF3UE_000435"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFD3633895.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            21619..22491
                     /gene="sdaAA"
                     /locus_tag="ACF3UE_000436"
     CDS             21619..22491
                     /gene="sdaAA"
                     /locus_tag="ACF3UE_000436"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFD3633896.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(22582..23682)
                     /locus_tag="ACF3UE_000437"
                     /pseudo
     CDS             complement(22582..23682)
                     /locus_tag="ACF3UE_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(23774..24661)
                     /locus_tag="ACF3UE_000438"
     CDS             complement(23774..24661)
                     /locus_tag="ACF3UE_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFD3633897.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(24738..25283)
                     /gene="nusG"
                     /locus_tag="ACF3UE_000439"
     CDS             complement(24738..25283)
                     /gene="nusG"
                     /locus_tag="ACF3UE_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFD3633898.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(25384..25554)
                     /gene="secE"
                     /locus_tag="ACF3UE_000440"
     CDS             complement(25384..25554)
                     /gene="secE"
                     /locus_tag="ACF3UE_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFD3633899.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(25578..25730)
                     /gene="rpmG"
                     /locus_tag="ACF3UE_000441"
     CDS             complement(25578..25730)
                     /gene="rpmG"
                     /locus_tag="ACF3UE_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFD3633900.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            25892..26536
                     /gene="cbpA"
                     /locus_tag="ACF3UE_000442"
     CDS             25892..26536
                     /gene="cbpA"
                     /locus_tag="ACF3UE_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFD3633901.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(26592..27095)
                     /locus_tag="ACF3UE_000443"
     CDS             complement(26592..27095)
                     /locus_tag="ACF3UE_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFD3633902.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(27108..27154)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            27692..28657
                     /locus_tag="ACF3UE_000444"
     CDS             27692..28657
                     /locus_tag="ACF3UE_000444"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD3633903.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(28756..29928)
                     /locus_tag="ACF3UE_000445"
     CDS             complement(28756..29928)
                     /locus_tag="ACF3UE_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3633904.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(29915..31060)
                     /locus_tag="ACF3UE_000446"
     CDS             complement(29915..31060)
                     /locus_tag="ACF3UE_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3633905.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(31074..31998)
                     /locus_tag="ACF3UE_000447"
                     /pseudo
     CDS             complement(31074..31998)
                     /locus_tag="ACF3UE_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            32115..33194
                     /locus_tag="ACF3UE_000448"
     CDS             32115..33194
                     /locus_tag="ACF3UE_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFD3633906.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            33191..33819
                     /locus_tag="ACF3UE_000449"
                     /pseudo
     CDS             33191..33819
                     /locus_tag="ACF3UE_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            complement(33929..34156)
                     /locus_tag="ACF3UE_000450"
     CDS             complement(33929..34156)
                     /locus_tag="ACF3UE_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3633907.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(34259..36847)
                     /locus_tag="ACF3UE_000451"
     CDS             complement(34259..36847)
                     /locus_tag="ACF3UE_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFD3633908.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(36867..37526)
                     /locus_tag="ACF3UE_000452"
     CDS             complement(36867..37526)
                     /locus_tag="ACF3UE_000452"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD3633909.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(37575..38078)
                     /gene="trmL"
                     /locus_tag="ACF3UE_000453"
     CDS             complement(37575..38078)
                     /gene="trmL"
                     /locus_tag="ACF3UE_000453"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFD3633910.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(38299..39165)
                     /locus_tag="ACF3UE_000454"
     CDS             complement(38299..39165)
                     /locus_tag="ACF3UE_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFD3633911.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            39274..39915
                     /locus_tag="ACF3UE_000455"
     CDS             39274..39915
                     /locus_tag="ACF3UE_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFD3633912.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(39977..41338)
                     /gene="mgtE"
                     /locus_tag="ACF3UE_000456"
     CDS             complement(39977..41338)
                     /gene="mgtE"
                     /locus_tag="ACF3UE_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFD3633913.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(41356..42255)
                     /locus_tag="ACF3UE_000457"
     CDS             complement(41356..42255)
                     /locus_tag="ACF3UE_000457"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFD3633914.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(42257..43054)
                     /locus_tag="ACF3UE_000458"
     CDS             complement(42257..43054)
                     /locus_tag="ACF3UE_000458"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFD3633915.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(43032..43736)
                     /locus_tag="ACF3UE_000459"
     CDS             complement(43032..43736)
                     /locus_tag="ACF3UE_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFD3633916.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            43867..44442
                     /locus_tag="ACF3UE_000460"
     CDS             43867..44442
                     /locus_tag="ACF3UE_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFD3633917.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            44560..45237
                     /locus_tag="ACF3UE_000461"
     CDS             44560..45237
                     /locus_tag="ACF3UE_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFD3633918.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(45316..47124)
                     /gene="pepF"
                     /locus_tag="ACF3UE_000462"
     CDS             complement(45316..47124)
                     /gene="pepF"
                     /locus_tag="ACF3UE_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFD3633919.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(47300..48298)
                     /locus_tag="ACF3UE_000463"
     CDS             complement(47300..48298)
                     /locus_tag="ACF3UE_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFD3633920.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(48524..49177)
                     /locus_tag="ACF3UE_000464"
     CDS             complement(48524..49177)
                     /locus_tag="ACF3UE_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFD3633921.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        14794 a        10394 c         8723 g        15572 t
ORIGIN      
        1 gtatataaac tatgtatatt ctttaatatt ttttgagaat gcacttcgta cataataaac
       61 tttaatcaca ttagtctttc atacctacga tcgatctctt tgactcgcac ccataaattc
      121 ataatagttt gtcggcgtct ttggacgttt cgaagatgag ctacgcattc tcttttttta
      181 tagacaaaaa agatagagac gaacatggag cttccaaatt tggatatttg atccaatttt
      241 ggaagctcca tttatttcgt gtctgtcttt ttattttttc cagctttcga ctaattcttg
      301 gttctctttg atccagtctt ttgctgcttg ctgtggatct tttccattgt tgatttccaa
      361 cataactttt tccatatctt tttctgacca atggaaattg tctaatactt tgtaagcttc
      421 tggctggtct tctttcaatc cttttcgaac catcgtatgg atctgctctt cgcttcccat
      481 tccgttttca ggatcttcta agtatttcag atcatatttg gcaaacatcc aatgaggtgt
      541 ccatcctgta actacaattg gttcgtgttt tttgatcgct tgacctagtg caacggtcat
      601 tgctcctgaa gaagatgtct ctactttcca gtctttcaag ttgtcatatt tttggatcgt
      661 gttttcagca gccgtaacta caccagctcc tggctcgatt cctatgattt tcttacctgc
      721 ctgatcggtt aactcatcga tcgaatttac atccatgtag gctggcactg ctaaaccaac
      781 ttttgctcct gtcaaattgg cacctaggtc ttcgacttga tctttatatt gtgcatattg
      841 tgaaccatga gttttaggta gccaagctga aaccatggca tctgactcgc catttgaaac
      901 agatttccac atgattgaat tatctaatgg cgtcatcgtt acatcatagc ccatttgttt
      961 caatacttca ccgactacat ttgttgaagc aacttctgta tcccattcaa cataagataa
     1021 gttgatacgt tttgtttctt tggcagatga aaaactccct ataccaatcg cacctaagat
     1081 cactactact acagcaccaa tgatcagtcc ttgacgtttt ttacttttct gtgttgttgc
     1141 tcctgcagct tttttattgt ttggctggtt caaatgctgt gtaaaacggt caatgatgat
     1201 tgctaagata actaatgcaa ccccgttgac aaatccattc ccgacttgtg ctctttgcaa
     1261 tgctgataat acgccgcgtc ctaagccggg tgcaccgatc atagaggcaa taacgaccat
     1321 tgaaagtgac agcattgttg tttgattgat ccctgccatg atcgtacttt tagctaaagg
     1381 caattctagt ttgaatagtt tttgacgact tgtgctcccg aatgaatcag aagcttctac
     1441 taattcttta ggaacttgtc gaatccctaa attcgtaaaa cgaacggttg gtggcagagc
     1501 aaagatgact gaggcaaata cccctggaac catcccgata ccgaaaaatg caactgctgg
     1561 aatcaaataa acgaatcctg gcattgtctg cataaagtca aggatcggtt tgataatact
     1621 ttgggcttta ctgctttttg ccatcaagat ccctaatggt accccaatga tgatcgagat
     1681 cacactagat aaaagaacaa gtgtgacagt attcatcaaa tcattccata gaccttggtt
     1741 ataaataaac catagaccga ttaatgtgaa caacgtaagt cctggacgtt tcttagaaat
     1801 aaagaaagct gctaccgtca ataacaagat aaacaaagga gctggaatca ctaacagtaa
     1861 atttgtaatc cccgacatca ctgcctgtcc aatcgtttgt aaaaatgaaa ataggccaga
     1921 aaaagttgtc gtaaaccatt ctgtgatatt ttctacccag tttgccactg gtaattgata
     1981 gttcaataga ttattcatgt tcactcacct cgcttgtttc tgctaatgct tcaatcacac
     2041 tacctcggat gacgacacct tttaattttc catcctctac aactgcaagt ggagtcggtg
     2101 agtcataaat aatattgaaa atatcactta ccaccatgtc tttcccaatc accgtcacat
     2161 tttcatctag gaagtcgatc aatggacgtt tttgcttcct agcttctaac gcttgatctg
     2221 cagtgatgat ccctttcagg tgtctctttc tgtcaacagc catcagcatg ctgacttctt
     2281 cattacgcat ccttgtcaat gcaacgtttg gtccatcaga ttcgatattc gtcgtcaatg
     2341 caggtaccat gatgttttga gccgtaagca ctttggaacg atcgacttct tccacaaatt
     2401 cacgtacata atcatttgct ggattggtca atatttcttc acctgttccg atctgcatga
     2461 tttcgccgtc tttcatcaag gcgattctgt ccccaatccg taaagcttca ttcaaatcat
     2521 gggtaatgaa aataatcgtt ttttgaacat tggcttgcag gtccagtaat tcgtcttgca
     2581 tttctcgccg gatcagcgga tcaagagccg agaacgcttc gtccatcagc aagatctcag
     2641 gatcatttgc taaagctctg gctaggccaa cccgttgttg catcccacca gataactgac
     2701 taggatattg gtctttaaat gaaagcaaac tagaattttc taatgctttt tctgcttttt
     2761 cttgtcgttc ttctttaggt acaccacgga cttctaaccc gtattctgta ttttccaaga
     2821 tcgttcgatg tggaaacaga ccgaagtttt ggaaaaccat attgatttta tgacgacgga
     2881 cttctcgcaa ttcttctttg cttaacttcg atacatcttc tccatcaata tagatactgc
     2941 ccgaagttgg ctcaatcaga cgattcaata gacggatcaa tgtggatttc ccactcccgg
     3001 aaagccccat gatcacgaag atttctcctt cttttacgtc aaaattcacg tcatacacac
     3061 caaccgttgc accggttttc tttaaaatct ccgttttcgg ctggtgatca ttcatcatat
     3121 ctaaagcggc ttgtgtcttt ttaccaaata tctttgttaa atgttttact tctactttta
     3181 ccaaacaaat tctccttttt tatgtaaatt catttttctt tctgaaaaaa gtgaccacac
     3241 tatgttaaca tcatgtagtc actttgtcaa aaatgaaaga aatttgcttg tccaaactga
     3301 aaaaaacttg gctaaatctt tgtaaataaa aggtttagcc aagttaatat ttttttaata
     3361 tttcacacaa tcattctgca agctgatgct ccgggtaaaa aaagtttgtc atacgctgta
     3421 gtgtatattc atttccaata aaatgaacga tgtcccctgc cgtaaattta gcataggggc
     3481 caggtgaaac aagcagttct tcattatgag aaattgcgat aactgtggcg ccagtcgcct
     3541 gccagatatt caactcgcta attgaacggt ccagatgcat tgctttttct gataaagata
     3601 attcaaacgg aagtaaagga ttcatcttat gtattcgctt cgtttgattg accagctgat
     3661 ccaataattg agaaaaatga ttcagctcat cttgttgctt ctccacactt gccatgattt
     3721 ctgcttttgt atcttggatg gattgtacat cttgatattg caataggaaa tcttttgctt
     3781 tttccttcga agcaacaaat gccccacttc catgccgtac ttccatgatt ccaagatcta
     3841 ccagcacatt gatagccttg cgggtagtct caggagaagc attgtacgta ctggcaagtg
     3901 ttgagcgggc atggatcttc tcacccactt tatatcggtt ttcaacgata cgttcggcta
     3961 aatcaacagc aatctgctgg tagcgcgggc ggacgatttt tttctttcca gacattttct
     4021 ttcctctttc tttttttact ttccctcatc ttactatgct ctagcaaaat aagcaaaaaa
     4081 ggggagaata gcctcttgca acgactgatc atcgcttgat ctgttccttt tttactgggc
     4141 aagctgtttg acagtcatca caattcttac cggattttaa acgagtatag acaattgcgc
     4201 ctgcacttcc aaagattaac acacttaata agaatgtcgc catcctattc ctctccttct
     4261 aatgacaata tagtataaaa ctggttcttg gattttggct gacggaacaa aacataaacg
     4321 agtcctatca tcagtaaaat agcaagatac gtccctaacg ctacctgtcc accctccaat
     4381 aagtgtccca actgataaat cacaaaacta actaaataag ctaaaccgca ttgatagcct
     4441 atggcgatcc aagtccattt cttggcattc atttcccgat ggatagcccc aattgccgca
     4501 aaacaaggcg cacaaagtaa attgaaggct aacaatgaat aagctgctgc gggagtatat
     4561 gtgtgttgta gcacttgcca gatttctctg ccattttcgg atacttccgc atgaccaaac
     4621 aaaataccaa atgtgccaat aatattttct ttagcgacca atcctgtaat cgctgcgact
     4681 gttccttgcc agtttcccca accaagcggc tgaaaaacaa ctgccaggat tcgcccgaaa
     4741 aaggctaaga tactttggtc ttcagaaaca ggttgagcat aaaaattata agaagagctg
     4801 aaccagatca cgatactaga aacaaagata atcgttcctg cttttttaac aaaagacttg
     4861 ctgcggtcat aggtttgtct taggaccgct gaccattgag gaaaatgata tgcgggcaat
     4921 tccatgataa aaggagctgt atctccagca aacaaacgtg tttttttcaa gctgattcca
     4981 gagaaaataa ttgcagtcat accaagaaaa taggcagaag gagctaccca agattgatga
     5041 ggaaaaaagg cccctgctac taaggcaata atcggcaact ttgcagaaca aggcatgaag
     5101 gttgtgacca tgatcgtcaa acgacgatct tgctcgtttt caatcgtgcg actggccatg
     5161 acgcctggca ctccacatcc tgtagcaatc agcataggaa tgaaggattt tcctgaaaga
     5221 ccgaatttcc tgaaaagtcg atccatgaca aaagcgatcc tcgccatata tccgcagtct
     5281 tccagaaagc tcaagcataa aaacaatata atcaattgcg gtagaaatcc taacactgct
     5341 cccacgcctg cgatgatgcc gttcaagatc agctcctgca tccatcccgc tacttgccat
     5401 tcagctaaca atctgccaac atgttctggt aaccatgtac caaacaatgt gtcattgatc
     5461 caatctgtcc ccattgttcc tactgtttga atagccagat aatagatcag ccacatcaca
     5521 aatgcgaaga tcggcaaggc taaccaacga ttcgttgcaa tctgatcgat tttgtcactc
     5581 atcgataatt ggaaagaatc atttgacaca acacagagtg tacatagttg ggtaataaat
     5641 tcataacgtt cattgaccag aatcgtctca ctatcgtcgt ccaatagttt ctctgttaac
     5701 tggatcagtt gctcgatctc tttttgctga gaaactgcta tctcgtaatc ctctcttacc
     5761 ttctgatctc gttcaaaata tttcattgca taccagcgtt tcttgccgct ttgttctcct
     5821 agtacatctt caatttcatg taaagctgct tctaaacgtg gatcatatgt acagggaaca
     5881 ggaatagaag gccgcttttt tgcagactcc tgaatctttt cgattagttt ttcgattcct
     5941 tgctttttca atacgctgat tggtaaaact ggtacaccaa gaccatagga aagcttttct
     6001 agattgattt tttttccttc ttttttgatg acatccatca tattcagacc aatgatcata
     6061 ggaatgtcta aatccaataa ctgcgtagtt aaataaagat ttcgttctaa attggtagca
     6121 tcaataatgt tgatgatcag ttcaggctgt tcctgaacca aataatctct tgcaatcact
     6181 tcttctggtg tataaggaga caaagaatag atgccgggta ggtcctgaat atgaatgttc
     6241 ggattttttt tcaacgatcc ttcttttttt tctactgtta cgcccggcca attccctaca
     6301 tattgattcg aaccagtcaa gagattgaac aagctagttt tcccgctgtt tggatttccg
     6361 actaacgcga tattcattct ttttcctccc tttgtatcaa gattagttcg gcctctgact
     6421 ttcgtaacgt cagttcatac cctcgcactg tcagttcgat tggatctccc agaggggcta
     6481 gttttcggat aactattttt acatttcgcg tcaatcccat atccattaac cgtcgcttca
     6541 ctgcgccttg tccgtggatt gctacgacga tcccagtctc tcctgctttt aattgatcaa
     6601 gagaagtcca gctttcagag gaagcagtct ttttattgac aaagatttga cctagtattt
     6661 cccgacttac tgccactcga tgacttttta ccagtaaaat ggcattgttg cctgataaat
     6721 tgacgacgac gattttactt ccggcaacga tcccgatatt ttgcaaatgg cgttttgttt
     6781 tttcttctgt ttcgattcgt tcgacttgat aaacgaaatt ctgctttgcc tgcgctaagg
     6841 tctgcatatt gattcctctc ttgtgaaata aatcatgtat taaaatcatt cattatatgt
     6901 tctaattttc ttacgtgtta cgcaaataaa tgagaatcat tctcacatag aatactctcg
     6961 gtaattgaga atgtcaatta tacttgtgat attatgagcg aatctttagt attgatagat
     7021 aaaaatgaga aaaaaatatt tcttcatagt tttccacaat tttttctcta ttaaatttgc
     7081 tattttccca cacgatactt gttttcagct cttttttcaa aaacacaaaa cttagtattc
     7141 cacagtttcc acaacacaat atgtagtgtt tgttgtttga cttttttact aagagtttta
     7201 tactatctat tatagataat aagaatgtgt tagaggaggc actcaccatg aacgtaaaaa
     7261 tcttttctaa aaataattgt atgcaatgta agatggtcaa acggttttta acagaaaatc
     7321 aaattgcttt tgaagaagtc aatatcgatg aacagcctga agcagtagac tggttgaaag
     7381 cacaaggatt ccaaagtgtt cctgtcatta cttctgatgc agaaacagtt atcggattcc
     7441 gtcctgatca gttgcgtaaa cttgccagct aacatgacta aaagaatcaa aacgtgatac
     7501 atggatttga agggcttgag acagcaccag tttttgtcgc aaacttccaa atcctttttt
     7561 aaagcttaaa aacaatgcaa tgatttgcaa tcaagcatca tcaaatacga aatgaaggtt
     7621 gggcgtacgt atgagtctta aaaatttaca agatgtcagt tatttcaagc tgaataatga
     7681 aatcaatcgg ccagtcaatg gtcaaatccc tttgaataag gataaagaag ctttagttgc
     7741 cttttttgag gaaaatgtca aaccaaatac gatgactttt ctatctatta tggaaaaaat
     7801 caattacttg atcgatcaag aatatataga agcagaattc attcaattgt attcaccatc
     7861 atttattgaa aagctatatc aatttttgga cgagcaacat ttttctttca aatcttttat
     7921 ggctgcttac aaattttatt ctcaatatgc gttgaaaacc aacgacggtt ccgcttatct
     7981 ggaaacttat gaagatcgag tagccttcaa tgcgctttac tttgcgaacg gggatgaaga
     8041 attagcactt gctcttgcag acgaaatgat ccatcaacga tatcagccag ctacaccttc
     8101 tttcttgaat gctggacgta aacgtcgggg cgaattggtg tcttgtttct tgactcaagt
     8161 cactgacgat atgaactcta tcgggcgctc aatcaactct gctttgcaat tgtcccgtat
     8221 tggtggcggc gtagggatta ctttatcaaa tcttcgtgaa gccggcgctc ctatcaaagg
     8281 atatgagggt gctgcaagtg gtgtcgttcc agtcatgaaa ttattcgaag atagtttcag
     8341 ctattctaat caattaggtc agcgtcaagg agctggcgtg gtttatttga acgttttcca
     8401 tccagacatt attgctttcc tttcagcaaa aaaagaaaat gcagatgaaa agattcgcgt
     8461 aaaaactctt tctcttggcg tgatcgtacc tgataaattt tatgaattga cacgtaaaaa
     8521 cgaagatatg tatttattta gtccatatag tgtcgaaaaa gaatatggtg tcccattctc
     8581 ttatgtaaat attacagctg agtatgatca tctagttgca aatccaaaca ttcgcaaaca
     8641 aaaaatcaaa gcgcgtgatc ttgaaaatga aatctcaaaa ttacaacaag aatctggcta
     8701 tccttacgta atcaatattg atacagcgaa ccgcgagaat ccaatcgatg gcaagatcat
     8761 catgagtaat ttatgttcag agattttaca agttcaaacg ccttctgtga ttaacggcaa
     8821 acaggaatat gaagtattag gaacggatat ctcatgtaac ttaggctcga caaatatcgt
     8881 gaatttgatg caaagcccta actttggtca atctgtgcgt acgatgactc gtgcattgac
     8941 atttattaca gatgcatctg atatcgatgt cgtaccaccg atccaaaacg gaaataagct
     9001 gaatcatacg attggattag gtgccatggg cttacacact tatcttgcaa aagaacaaat
     9061 ggaatatggc tcagaggatt cattagactt tacaaatatt tacttcatgc tgttgaatta
     9121 ttggacactt gttgaaagca acaatatcgc tcgtgaaaga aaacaagttt tccataattt
     9181 tgaaaaatca gcttatgctg acggcactta tttcgaaaaa tacgtaactg gagaattcca
     9241 gccaaaatca gaaaaagtca aagcattgtt tgaaggcatt tttatcccaa ctgctgaaga
     9301 ttggaatgct ttgaaacaag cagtaatgaa agatggactg tatcatcaaa atcgcttggc
     9361 agtagcacca aatggctcaa tttcatatat caacgatacg agtgcaagta ttcatcctat
     9421 cactcgcatg atcgaagaac gccaagagaa gaaaatcggt aaaatttatt acccagcgcc
     9481 ttatctatcc aatgagacga ttccgtatta cacttctgct tatgatatgg acatgcgtaa
     9541 agtaatcgat gtttatgcaa tggcacaaca acacgtcgat caaggcatga gtttgacttt
     9601 attcatgcgt tctgaaatcc cagaaggcat ttatgaatgg aagacaacaa cgaagcaaac
     9661 gacacgtgat ttgaatattt taagacatta cgctttccac aaaggaatca aatccattta
     9721 ttacgtacgt acctttactg atgatgcaga agaaatcgga agcaatcaat gtgaaagctg
     9781 cgtgatctaa tatcatagat agattcgctt attcatattt taattaaagg agcattctca
     9841 tgtcagaaac atattatgaa gcaataaact ggaatgaaat tgaagatatc attgataaat
     9901 ccacttggga gaagctgaca gagcaatttt ggctagatac acgtatccca ctttcaaatg
     9961 acctagatga ttggcgtaca ttgtctcaat tggaaaaaga tacagtagga catgtatttg
    10021 gcggtttgac actgctagat actgtccaat ctgaaagtgg catggatcag ttgcgtaaag
    10081 atgtccgcac tccccatgaa gaagccgttt tgaacaatat tcaattcatg gaatccgttc
    10141 atgccaaaag ttattcttct atttttagta cactgaatac gaaaaaagaa atcgaagaaa
    10201 tttttgactg gacaaatacg aatccttatc tgcaaaaaaa agctgagcgt atcaatgaaa
    10261 tctacaaaca cggtacaccg ctagaaaaga aaattgccag cgtcttttta gaaacattct
    10321 tgttctattc aggtttttat actcctcttt attatttagg aaacaacaaa ttggctaacg
    10381 tagcagagat catcaaacta atcatccgag atgaatctgt acatggaacc tacatcggtt
    10441 acaaattcca attaggattc aacgagttac ctgaagcaga acaagaaacg ttaaaagact
    10501 ggatgtacaa tcttctttat gagctttacg aaaacgaaga acgttataca gaagaattat
    10561 acgatccaat cggctggaca gaagaagtca agacattcct acgctataat gccaacaaag
    10621 cattgatgaa cctagggatg gatccactct ttccagatac tgccaatgat gtcaacccaa
    10681 tcgtaatgaa cgggatttca acaggcacaa gcaaccatga cttcttctca caagtcggaa
    10741 acggctattt gttaggtcat gtagaagcga tgaaagacga cgattatttg attggattgg
    10801 aataaggatt tattttaatt caaaaatttt tcgaaaaata aaaagagttt agcgtacaga
    10861 tattttaaat gtacactgaa ctctttttta tgcttattca cttgtttctt ccagcacttt
    10921 tggactgtct aacttttccg aaacatgttc cattcttctc aataaataga ttttccggat
    10981 atttaatatt atcgtcttaa tcactgcata gacaggtatg caaatcagca tgcctaatat
    11041 tcctgcgaca cttcctgctc caatcaatac caagatgatc gtcaaaggat ggatattcat
    11101 tgatttccca aataacaacg gcttgatcaa atttccatct aattgttgga tcactaaaat
    11161 cgacaacgcc atatacaaag cttgaaatgg agagataaac aaaccgacaa tgattgctgg
    11221 taccgctcca ataaaagggc cgacatacgg gataatattc gtgattccgc aaatgaccgc
    11281 aagcaacaag ctataaggct gatcgaatat tctcattgcc aaaaagctca ttacaccaat
    11341 aatcaaagca tctaagatcg tactgctgat ataggcagat aatgtttcgt ttaattcttt
    11401 taccgtttgg cgtaactctt tacgaatcgc tttcggaaag aagtgagaca acgcatcaat
    11461 aaatttgtgc ccatccttga acataaatag caaaataaat ggaacggtaa ataacaaaat
    11521 aaaaaattgc atcataaatg aaatgatttt tgagacactt gcagataaac tgactaatat
    11581 gatattgaac aaattactaa gagataaatt tgctgatgct aattgttctt ccaaattgaa
    11641 atttttaaac tcttcccgct gcgccaattc atttaaccat ttgcttgttt catctgcata
    11701 cattggcaag ctctgggtca attgaattgt ctgttccatt aactgaggca ctacattcat
    11761 gacagttaaa acaactaaaa tgattacgac caaaaacgtc aataaaaaac cgaacactct
    11821 cgggatccga tgcttttcga gaaaaacaac gattggatcg aacatataat agataaaacc
    11881 agcaacaagc aatggtaaaa aaactgccga aagcattttc aatattggac taaaaatatt
    11941 cggcatttgt aaaataaagt acacgccgat gatcgtgagt actagctcca ctgtccagaa
    12001 aaataatttt gattgtttaa aacgtgattg catacatctc ctccaaggtc ctttgatact
    12061 tctattctat catttaacaa agagttacgc gctgagattt tcatttgctt aaaaaaaaca
    12121 aaaaaaataa acatatttta atgagtagac gagtacttaa acaaaaacac ggtttggagt
    12181 agtgacaaaa attatactgc agtccctttt tccaaataaa cggtgttcaa aagcttgcat
    12241 cttcgtaata agcccagcca aacgaaaaat ataaggaact atttttattt ggctgggctt
    12301 attacttgat gtaggacatc tattttacaa cctcagatca tttattgcgc aatactgact
    12361 aaatgcaact ttgtgatatt tttgtgtacg gacaactcct cgatcacatc ggcataagtg
    12421 agcccttttg gaagatcaat cgtatagata tttttgtaca ctcggtagtc atcaacgaat
    12481 tttacgtcaa aattcacatc ttcgattacg atatttttct cttcaaaata atcggtaaga
    12541 aaatctttgg tttcttttct atggataaat tggatttcta actttttagt cgtaggtaca
    12601 tggatcacgc gtttcactac tgtgagtgca atagcaatcc cgataaaact gatgatcgca
    12661 atggaatagt aacccatgcc gatggcgatc cctaatccag caattgccca taaagaagcg
    12721 gcagtcgtaa gtcccgtcac cgattgtttc gtgacgatga tcgttcccgc gcctaagaaa
    12781 ccgacaccac tcaccacttg agcaatcagc cttgcttcat ctgaacgaat cgttccagca
    12841 agctgtggat actctaaagc atctcttaat gcaccactag cgatctcaac ttggatcaat
    12901 gcaatgatac atgctcccat acaaactaaa atatgcgtac gcatacctgc tggacgattt
    12961 ttatattgtc gttcaaaacc gattgctccg ccaaatagca tagcgatccc taaacgtaaa
    13021 ataatctctg gaattgtcaa taccatatca ttcatctaaa caccctccag tccaatatat
    13081 catgtctgaa aggagcagac aaaaaaagtg caatttttac ctcttacgaa aaaaggactg
    13141 tgacaaaatt tttgtcatag tcctttttat gaataaacgg tgttcaatca gctgaccctc
    13201 ggtattactc aacaaacggc aaaatatggg gagctatttt tcctttgtct tctctaatac
    13261 tcaggtcaaa acgctgattt cacaacctct ttagcctact attgaaaatt acaacttact
    13321 tgctgcttct tcatcgatga tcacaacaac attgtcgtga ttttgcaata cacttgctgg
    13381 caaatgattc gttacaggtc cttcaatcat ccctttgatt gcatcagctt tgctttcgcc
    13441 aaatgccatc aagacgattt ctttactttt cataattgaa ccgattccca ttgaaacagc
    13501 ttttgttggt acatcttctg ctttatcgaa gaatcgtttg tttgcattga ttgttgattc
    13561 tgttaagtca actactgaag tcgttccgtc aaatgaagca ccaggttcat tgaaaccgat
    13621 atgtccattt tgcccgattc ctaagatttg gatatcgatt ggatgtgcat cgatgatttg
    13681 atcatacttt ttgcatgctg cttccagatc ttctgctttt ccatctggta caaacgtttc
    13741 tttgaatggt tttttatcaa ataattggac atccatgaaa tgacggtagc tttgttcatc
    13801 tgaaccgcct agtccaacgt actcatctaa gtttacagaa gtcatttcac tgaaatccaa
    13861 atcgcttgaa gtcatttctt tatataaagt aactggtgtg cttcctgttg ccaatcctaa
    13921 tacttttgca cctttgttca taccttcttt gatgatttca aatgcttttt ttccgccttc
    13981 ttcagcgttt tttacacgaa tgatttccat agtgattgct cctttatatt ttggtatagc
    14041 ccaattatag cattcttttt ttctttttac aataattagt atagaccaaa ttgcattttt
    14101 ttcattttct tgacaataaa taggaatccg tgttaggttt cataagatgg ttcaatcaaa
    14161 caatccatgt tgcatgaaaa ccaagcaagt gattcactgt ggacgcttta tgtctgcagt
    14221 ttttttatga aaaaggagtt attatgagta tactgacatt aaacaacatt acccagcaat
    14281 ttggcgacaa aatcctctat gaaggtgtcg atctgcaatt aaatgctggc gaacatcttg
    14341 ggctgattgg acaaaacgga gccggtaaaa gtacattgat taaaatcatc actggtgaga
    14401 tcttaccaga tgacggacag atccattggc aaaaaaatat tcacaaaggt tacctcgatc
    14461 aatatgtgga agtcgatgaa acattaacaa tcgaagaatt tctaaaaact gcgtacgcaa
    14521 aagaatacga aaaggaagaa aaaattgctt ttctttacca aacatatagc gagaccttcg
    14581 atgattcctt gctggaaaaa gctgggaaac tccaaacgga attagaccaa ggagtgtttt
    14641 atcaaatcga caccttagtt gctgagatga gcagcgggtt ggggatcgat gtcttaggtt
    14701 tagattcact gttgaaaaat ctaagtggtg gacaacgttc aaaggtgatt ttagcaaaac
    14761 tacttttaga aaacccagat gttctgatct tagatgaacc aaccaatcac ttagatgatc
    14821 agcatatcca atggctgacg cagtttcttc aggattttga cggtgcgtat atcgtgattt
    14881 cccatgacca agaatttctt gatcagatca ccacccatat cgcagacatc gagtttggaa
    14941 agattactaa gtatactggc catctaaaac aagcattgaa acaaaaggaa caaaatcgcg
    15001 aaagctattt gcgccaatat catgctcaac aaaaacaaat cgaaaagacc gaagcttata
    15061 ttcgaaaata caaagccggt tcccgatcaa cgatggcaaa aagccgacaa aaacaattag
    15121 ataaaatcga acggctgacg cctccagctt cagcaagtaa agctgtcttt gattttccat
    15181 tctcgcctat tgtcacgaca ttagcagtgg aaacaactga tttagtcatc ggatatgatc
    15241 gaccgctact tgcacccatc aatttgacca tccgctttgg tgaaaatatt gccattcgag
    15301 gcttcaacgg gattggaaaa tctactttat taaaaacact gatcggtgag attgaaaaaa
    15361 taagtggcga tttccacttc ccagataaca caaaaatcaa ttacttttca caagatctgt
    15421 actgggaaaa tccattagaa acaccactac aatatttaag cagtcaattt ccaaaagcga
    15481 ctatcaaaga attacgtcgc caactagcta aagcagggtt agttaatcaa ttagcaagtg
    15541 aacctctcac tacattaagt ggtggggaac aaactaaggt gaaacttgca cagttgacaa
    15601 tgaaccaagg taatttactg attctcgatg aaccgacgaa ccatatcgat caagaaacga
    15661 aagaaagctt acaagacggg atacagaaat ttccaggaac agtaatcatc gtctctcatg
    15721 aacaagaatt ttatcaagat cttgtgcaac gagtcattga gattgaacca aaataaacgt
    15781 ttgattgaat agttgaaaaa aaggagctgt gacaaaagtt ttgtcacaac tccttcttct
    15841 gaataaatgg tggccaatta gctgaccttc ggtattagct caaaaaacgg caaaatatga
    15901 ggagctattt ttatttggct attcttatta cttgatgcag aacagctttt cacaacctct
    15961 tttcgtctat tttttatttt cgagatttct ctttccttta aaaacaactg tttgaaagaa
    16021 gaacgcacat ccttgaaaaa caagcccgct aaccgttaca cctaaccagc catactgctg
    16081 ccacattgtc gtccctagca atgaaccagc cgcacctcca ataaagtaca taaacataaa
    16141 tacagtatta tttcggttgc ttgctgcttc acctagccct tgtactcgtg tttgattggc
    16201 gacttgacca aattgattcc cgacgtctaa taaaataata gctaaaagca aaatggccaa
    16261 atggcttccg ccaaccaata aagcaataaa gcttattgtt tgcataacaa gtcccatata
    16321 cacgattttt ctttcagaat aagaatctgc cagtcgtccc acgataggtg cagcaactgc
    16381 tccagacaaa ccaaaaatcg ctaatatccc tgcttcgaat gttccccaat tgtaggcggg
    16441 actgctgata taaaaaatca acgtagacca aaagatcgaa aatgttccaa acatgaaaaa
    16501 tccactgact gccgcttctc ttaatagacg ttgagaagca actaaatgcg gcaaactttt
    16561 aagtgaatca aggtatgaaa cagctgtact actttgctgg acagaacgcg gcattttcca
    16621 gtaaagcaga agtgtaagaa ttccgactgc acataaagca aataaataga tcatccgcca
    16681 agaaaaaaga ctggcaacaa taccagatac cgtccgagaa agcaaaatcc ccacgagtaa
    16741 accgctaagc aatgtaccca tgaccttccc tcttgctttt ggtcccgcta gtaccgcacc
    16801 gtaaggaatg atgatttgcg gcacgatcga aagtaatcct attaaaaaag aagcgcatgc
    16861 aaataacgta aacgaaggcg caaaaaaagc ggccaacaga gagacggcag ataacgctgc
    16921 cattcgaatg atcaattttg gacgatccac cacgtcccct aaaggaacta aaaacagtaa
    16981 ccctaacgca tagcctaatt gggtcaacat cgtcaatatc ccgactgcac ttgtgctaac
    17041 agataaacta gctgctactt ttgttccaat cggctggatg taatacatat tggcaacaac
    17101 aacgccacaa gtgattgata atagtaaaat aagcgaagtt gttaaaggtt ttttttcatt
    17161 actcttcatt gatttccccc atttcctatc ttagtttaca acttatggaa aagattggaa
    17221 atagaaaaat acaactattc gccacactta ttatttgtgc ttttgttttc cttgtttttt
    17281 cttgcgatct ttataaatga agacaactaa ccctactagc acagtaacac ttgcaaccaa
    17341 cgtgactgca gttttgttat atccgtgaaa cagagcttct ccaccacacg catacaacac
    17401 agacgaaggg atgactccaa tcacgatcga caatatgatt tgctgtagag gcaatttcat
    17461 cgcatctgca gcaaaattga ccatagaaga tggaataacc ggtatcatat agcctaacat
    17521 tacacctatt tttggatgtt tcatttgtcg gattgcttgc acccaatgat tcgtttcggt
    17581 tttcttatct aaaaatttta agcgatgcat aaggaaaatt gcagtgatgt taccaagagc
    17641 attacccaaa atgttgatga tcgcacctgt cagtggtcca aagctcaaac cagcaatgac
    17701 tccaactact gaagtaggaa tacctggaac agcacacatc accgctgtca atacgatcaa
    17761 gagtatcgat gcaaaagtcc catgcgaacg aatatgtgcg agtagctctg ccttactcgc
    17821 tctcggattt aaaaataatt ggatgtctgt ctgatattct aaatacaacc gatagcccac
    17881 taccagtatc agaatgattc ccaacgagat caatatcaat cggattattt tctttttcat
    17941 atttcctcct gaaaaaaatc tatattcatt aaataatagt ttaacataaa aacaaaaaag
    18001 caccgaaatc caacatagga tctcagtgct tttaaatagt aaaaattatt taacagttac
    18061 agatgcgcca acttcttcaa gtttagcttt caattcttca gcttcttctt tagatacgcc
    18121 ttctttaact ggtgcaggag cgccatcaac tacagcttta gcttctttca agcctaaacc
    18181 agttgcttca cgaactgctt tgataacttt aactttttgg tctccagctg cagttaattc
    18241 tacagtgaat tctgtttgtt cttcagcagc agcagcgcca ccagcagcag ctacagctac
    18301 aggagcagca gcagatacgc caaattcttc ttcaatagct ttaactaggt cgttaagttc
    18361 taggatagtt gcttctttta actcagcaac gatgttttca atgttcaatg ccattataat
    18421 ttcctccgtt taattgttct tttttattta atgctttatg cggcaattaa gctgcatctc
    18481 catcttcttt gtctgccact gctttgacag cgtaagccac gttgcggact ggcgcttgta
    18541 gtacagatag caacatagat agaagtcctt cgcgatttgg caattttgcc aatgctgtga
    18601 tttcttccaa tgaagagact ttaccttcga tgataccgcc tttgatttct aatgcttttg
    18661 cttctttagc aaattcgtcc atgattttcg ctggtgcgac tacatcttcg ttactgaatg
    18721 caacagctgt aggtccagtg aatacttcgt ccatgccttc aaggccagct tttttagctg
    18781 cacgtgaaag aatagaattt ttgataactt tcatttctac gttagcatca cgaagttgtt
    18841 tacgtaaacg tgttacttca tcaactgtta atccgcggta gtcaacgact actactgatg
    18901 cagctgctgt aaatttttcg cttacttcat caacgattgc tgcttttttt gcgataattg
    18961 cttcactcat ttttgagttt cacctcctga attttgatgg aagagttttt tgcactgaaa
    19021 aggcaagtca cttttatagt tactttgctc aaccagtatt attcatcacc tattcacttc
    19081 gttcatagtg attctactcg ctttgctcga aaggaaactc ctttcgcttt gctcaaccag
    19141 tattgttcat catctcttca cttcgttcat agtgattcac aataaaaaac tctatgccac
    19201 cgcagacata gagggactat tgaatatatt caataaacgt cctcggtagg aaattaaggc
    19261 ttgatgccac ctactgtctt cggtacaagt taattattaa cctcaactag cttagcatgc
    19321 taaactagtt gagtcaagaa ttatttttca gttggatcaa tcaacattct aatatttaat
    19381 tagaaagaag cttggtcaac atggatacca ggtccaaatg ttgttgtgat cgttacattt
    19441 ttcatgtatt gacctttagc tgctgatggt ttagctttta gcaatacatc atggattgct
    19501 gcaaagtttt caactaattt ttcatcgtca aatgaaactt ttccgattgg tacatggata
    19561 tttccagctt tgtccacacg gtaagttact ttaccagctt tcacttcgtt tactgctttt
    19621 gttacgtcca ttgtaactgt accagtttta gggtttggca ttaagccttt tggtcctaat
    19681 actcgtccta gacgacctac agtagccatc atatcaggtg ttgcaacaac tacatcaaag
    19741 tcaaaccatc cgttttggat tttttgaacc atgtcgtcgt cacctacgaa atctgcacca
    19801 gctgcttcag cttcttttgc tttgtctcct ttagcaaaaa ctaaaacagt ttgtgtttta
    19861 ccagttccgt ttggtaatac aacagcacca cggatttgtt ggtctgcttt tttagggtct
    19921 acgttcaaac ggtatgcaac ttcaactgtt gcatcaaatt ttgcaatgtt tgtttctttt
    19981 gctaaagcta ctgcttcggc aacaggataa actttacttg aatcaacttt ttttaatgca
    20041 tcttgcattt ttttgctctt tttagccatt ttggttcctc cttgattgtg gttataacgg
    20101 ttgtacctcc cacgtgttct atatctttca atatagagcc aactgagaag ctgctgtctt
    20161 agggtgtata gattattcta cagtgatccc catgcttcgt gcagttcctt caaccatgcg
    20221 cattgctgct tcaacgttag ctgcgtttag gtcttccatt tttaattcag cgatttctct
    20281 tacttgatcg ctagaaactt tcgcaacttt atttttgttt ggttcgcctg aacctttttc
    20341 gattttagct gcttttttca atagaacagc agctggcggt gtttttgtaa cgaatgtgaa
    20401 tgaacggtct tcgtatacag aaataacaac cggaatgatc aaacctgctt gatcagctgt
    20461 acgagcgttg aattcttttg tgaatcccat gatattgata cccgcttgac ctagtgcagg
    20521 acctactggt ggagctggag ttgctttacc tgcaggaatt tgcaatttaa cgattttttc
    20581 tactttcttt gccacgagac atacctcctt aagtccgtga tgtggttaat tggagatgca
    20641 tatttctcct cccacgtttt atctgatctg aaaaaatcca gacaaataat gtgcaaaaca
    20701 atgcacactg gtacagtata gcaaatttat ttgttttttc aagatttttt tctgctattt
    20761 ttacattttg cttgaataaa cgctaaattt attctaaaaa aacaacaatt tttcgttctc
    20821 atttcttctt ttatgttaca cttgcgctag catggttcaa cagatgaaag caaacaataa
    20881 cacggttttt tagacccttg tacaaagatt cctacataac aaaatgaggt ggagaaaatg
    20941 aaagatttaa ggtatagaag tgtctttgat attattggac ctgtgatgat tggtccaagt
    21001 agctctcaca ctgccggagc tgctagaatc gggaaaatca tacgtagtat atttggcgaa
    21061 cagcctgatt ctgtagatat ttatctatat gaatcatttg caaaaaccta tcgggggcac
    21121 ggaacagata ttgcattagt tggcggcctg ttagggatgg aacccgatga tgaacgttta
    21181 gctgattctt tgaaattggc atatgaagcc ggtatggaag tcttgtttgt tcctaagagt
    21241 gaaaaagccg aacatccaaa ctctgtaaag atgcttctaa aaaaaggaac acgaaagctt
    21301 tcagtcactg gcatttcgat cggcggtggc aatatccaga tttctgaatt gaatggattc
    21361 aaaatttctt taagcatggg tactcctacc ttgatcgttg tccaccaaga tgttccaggt
    21421 atgattgcta aagtgactag tatactttct gagaccaata cgaatatcgg cactatgaca
    21481 gtgacacggg aatcaaaagg tgaaaatgcc attatgataa ttgaagtaga tgatcctcaa
    21541 gtagaagaaa cggtaaaaag actcaaacag ctgccaaata tcgacagcgt aaattatttc
    21601 gattaaggag ctaaaaaaat gtttttatcg attgaagaat tagtagatca agcaaaagct
    21661 tatccaagtg tagcagaatt gatgattgca gttgaaatgg aaatgagtgg ccgttcccgt
    21721 agtcacatca tcgagatcat ggaaaaaaac ctctcagtaa tggaacaatc aatcaacgag
    21781 ggaaaagaag gtgttacctc cgtcacagga attaccggtg gtgatgcaaa aaaattagat
    21841 gattatttaa atgaggcaga ctttttaagt ggagaaacaa tcttaaaagc tgtacgcaat
    21901 gctgtagctg ttaatgaagt caatgcaaaa atggggttga tttgtgctac accgactgcc
    21961 ggaagcgcgg gtgttgttcc tggtgtgctg atggctgtcc gagatcggct tgatttgaca
    22021 catgaacagc aattggaatt cttatttacc gctggcgctt tcgggttagt catcgcaaac
    22081 aacgcttcta tcagtggtgc agaaggggga tgtcaagcag aagttggttc tgcaagtgca
    22141 atggcagcag cagctttggt ttgtgcaaaa aatgggactc ctcatcaagc agcacaagca
    22201 gtagccatta cattgaaaaa tatgatggga ctgatttgcg atcccgttgc aggcttagtt
    22261 gaagtcccgt gtgtcaaacg taatgcttta ggctcttctc aagcttttat ctctgctgat
    22321 atggcattag cgggtatcga aagtgtcatt ccgccggatg aagtcgttgc tgcaatgtac
    22381 caagtcggac gtcaaatgcc gtcgattttc aaagaaacag cagaaggtgg cttagctgtt
    22441 acgccaactg ctaaacgact tgcggaagag attttaaata agagggcgtg ataaagctcc
    22501 ttaatttcga gtattaagag attagttatc ttcataacaa aaaacgaaga gaggactaat
    22561 tgcccttctc ttcgtttttt attaatccat caatttcgta ttttttactt catcgatcgt
    22621 ttttgttcct gcaagttgca tcgtgatcga caattctttg ttcaggtgtt caaaaacaga
    22681 tgttactcct tctgccccac ctagattcaa cccataaatc actggtcggc caatcgcaac
    22741 taagtcagca ccacttgcca gagctttgaa gacatgctct cctcgacgga caccagagtc
    22801 gaaaatcact ggtacacgtt tgttgactac ttcggcaatt tttggcaata cttcaaagga
    22861 cgcaggacct ccatctagtt gacgtccacc atgattggat acccagatac catctgcccc
    22921 tgcagagata gcgattactg catcttctgg cgattgtatt ccttttacga taactggaag
    22981 atgggtgatt tctttgattg ttttgatgtc atctggtgtc aagccttgtt ttgcagctgc
    23041 ataaatttct gcgattcctt ttccttcgcc attaccactt gcactttgtt cgctatacgc
    23101 agctaagtta ggcattggta atggaaattg gaattgattg atgacgtctt cttcacggta
    23161 accaccgagc gttgaatctg ccgttaaaat gatagcttta gcccctgctt ctactgcttt
    23221 gttcaaaatg aactcattga atctgtcgtc tttactcata tataattgga aaaactgcgg
    23281 tgcgcctggc gctgcatcgg ctgcgtcttt gattgtcgta tttgcataag tgctgatgga
    23341 aaagattgat ccagcagcag ctactccttt agctgtatca gcttcccctt tttcatgtgc
    23401 caatccttgg gccgctgatg gcgcttggat aatcggtgta tctaattcaa ttccgaaaac
    23461 agatgtatgc aaatcggctg agtcgattcc gcgtaatatc cgtggcatga ttttctttgt
    23521 attaaaagaa gtcgtatttt ctttcatcgt ccactcatct tcagaaccac cgcgaatata
    23581 gccaaaagct cctgcttcca tgcgctcttt tacacgacct tctagttagg caatgtttac
    23641 aatatcgatt ggatgttctt cattacttgt atgataagtc atagtagatc cttctttcat
    23701 cttcttgatt acatataaat catactaaac ttacaaaaag taagcaaaca tttactctca
    23761 gatactttta tcgctattct ttccaaataa atcgacttac aagctgatct acttcttggt
    23821 tttcatgaag catactatga gaggcatttt cacctgtcac tactttttcc tctatttcat
    23881 ttccgcgttg cttcaacaac gcatagaccg ctaatgcact gtttaacggt actgttccat
    23941 cactcaagtc tgtttcatct agttgaccag caatcaagaa aaatcgagtg gttataggaa
    24001 tattaccgat catttgctgg taatcttgat agcggttaga aacgacagca ggcccctttg
    24061 ctaactcatc tgtcagagac tgcgcactat catcgacaaa atcattaaaa ggcgcgccaa
    24121 ttgctgttaa tgtctgaact tgtggcaatg acgtatcctg tccatacgtt cctaaatagc
    24181 gtagtgcact aactcctccc atggaatgcc ccactatgtt gactttatct atgccgtagt
    24241 tttctttcag atacaaaaga caagttttga tccattctgc ttgattccac tcgttatttt
    24301 tattatcttc aaacaatact tggaccatcg gattgtctgc ttttccagac aaatctcctg
    24361 ttgcttgtat ttgtccatct gttcctactg ttaaaaccaa ttcttttact gcttgctgat
    24421 ttttttccaa acgccgcaac atccctttaa aggaattttc tgtcccgctg tagccgtgga
    24481 aaaaaagtgt tggaatagtg gttttttcta tcactttact ggattctgcc gttttttctt
    24541 tatcagaaac ttcagtagta tttatcttcg tcgtctggca accacttaac gcaaacaaac
    24601 tgataaggac taaagctgct gcagttgcac gtttgcataa atttttgatt ggttctgtca
    24661 tacacctctt cctttccata tagaaaaaag aaagacttga aaggccaatc atatgatcga
    24721 catttcaagt ctctttatta atcgatttta tctacttgat cgaaatcaag ttctgtactg
    24781 gtttcacgtc caaacatatc gatgttgact ttcaattttt ctttttctcc gtcaacttct
    24841 gttacttgtc cttctaatcc agcaaatgcg ccttcgatga ttttcacgac ttcgccaact
    24901 tctacttcta gatcattttg tcgcaggctc ataccgatag aacgcaagat atgattgact
    24961 tcttctggaa gtaatggtgc tggtttgctt ccggctccgt gtgaaccaac gaatcctgtc
    25021 acaccaggtg tgttgcggac aacataccat gaagcgtctg tcatgatcat ttcaacaagt
    25081 acgtatcctg ggaatgtttt atgaacgatt tctttttctt tcccattttt gacttcagtt
    25141 tctttttctt caggaacaac gacacggaaa ataaagtcgg ccattttcat actttgcgca
    25201 cgagattcga tatttgcttt tactttgttt tcatatcctg aatatgtatg caagacatac
    25261 cagttttttt caaaagattc cattgaaggc tcctcatttc attgtaaaat aaaaaaacct
    25321 cagtacaccc gaagtttttc tttcgcttca ttatagcact aaaagtacgt tgtggctagc
    25381 gagttatttt aaaatccagc caaataagct ttggatggct gtatccatta cgtaaaacat
    25441 caatccgaaa ataatagaag tttcgatgac tactaacgta tctttacgga gttgttttct
    25501 gcttggccaa gttacttgtt tgatttcatc ttttacgctt tttagaaatt tcatgagaca
    25561 acctcccttg ctactgttta tttcgtttct ttatgtaatg tatattgatt acaatattta
    25621 caaaacttat tgatttccaa acgttcgccg ctttttcctt cactgactga ttttgtgtag
    25681 ttgcgagacc cacaaacgga acaagcgagt gctgcttttt tctttgccat ttacttctgc
    25741 ccccttgctg agaatcagac ttatacttca taacagtatc acgtaacttt ttacttgtca
    25801 atttgtgaaa taaactatct attgttttgg ataaaattat gatatgatta atttgaaatt
    25861 aagctaaaat gagacaattg gaggtatagc gatgctatta aaaacacttg tatataagaa
    25921 aaaagatctg acaaccgtta cagagactag tacattagaa gaagcattaa aaattttaga
    25981 aacttccgga taccgttgtg tgccgatctt agattcttca ggtaatattt tccgtggaaa
    26041 catttacaaa atgcatatct atcgtcataa agcaaatggc ggtgatatga cgcttcctgt
    26101 cactcatctt ttgaaaaacg ctacaaagtt catttacctg gatacttctt tcttcaaagt
    26161 attctttacg atcaaagagc ttccttatat tgctgtcctt gacagtgaaa atcattttta
    26221 tggtattttg acacatagta cgttgcttaa tatgctctct caatcttgga gcgtagaaca
    26281 aggaagctat gtactgacaa ttgcttccac aggaaagcaa ggagatttgg ctgctattgc
    26341 aaaaatcatt tcaaaacaca gcagcattgc cagctgtatt actcttgata tcgaaaaaga
    26401 cgaatacatt cgacgtacat tgatcacgct accggctaac actgaagcga aagtatgtga
    26461 aacgatcgtc aaccacttag agaaaaagaa ttataaagtg gtagaaattg aaaatttgca
    26521 aaaccaagaa gcataatcaa aaagcgaaaa aagaaaacag ctaatctgct ttcttttttc
    26581 gctttttata attagacacg cttttcaaaa tcaagcgcgc gatctaaata atacatcaat
    26641 ggtgctgaaa cagccatgac gataaactca cttaatgcaa gcgtgccata ggttgtccaa
    26701 aatgcttggc cacctgttgg aactaacata taagcaatca gtcccatgct gatggtaaag
    26761 aagatcgtgt tcaatactaa acgcatcttt acatttttca ctttgttttg caataaagct
    26821 gtcaggccta aagaaagcaa tgtttggccg ccaccaaaaa ccacatccat gataccaaaa
    26881 ccaaagaagg cattatagac gatgaccccg cctaaaactc cccaaagcaa tttacggtta
    26941 aagacaacta aatgattcaa actttctgaa atacgaaact ggatcggccc tgaggataca
    27001 ggcgcaacta aaatagttaa cgctagataa agagccatga tgatgccatt tacaacgatt
    27061 acggataacc gttgtctgct tttcgttttt tgcattttct ctcctctttt ctcctagttt
    27121 ttttaacgcg ggatggttga tgaaccgcgg ttatgtgaaa caaacaataa ttataacaga
    27181 cttttcattt atttcaatcc gtcttatctg cttttaaaaa agcaaaagct taaacaatgt
    27241 aaacgtttgc taaaaatcgt gggatatggt ataaagtaag tgtaaggggt cataagaatt
    27301 cccagtaaag cagacgaagt aggatctgca agaacagaat tgttgtgaaa cttaaataaa
    27361 taaaaaagga tgtgggaatt tgagcaacct cttactagag aacggtctag caagcagctg
    27421 aagatctaag tggacatgcc gaaccttgga acttctcctt acgtaagtaa tggatcatgc
    27481 gcttgctagg cttttttgtg tttttcggtc ttcggacctt tttcattttc ctagacttct
    27541 gctataataa ccaagaatta attttgtaac agattttttt gaaaaaacaa gtttctttca
    27601 ttcaaaaaat agaaaaagct tgctaattat tggttaacca gcaaacagga gtattaaaat
    27661 atcttgtttt attgaatagc aggaggaaat catgaaattc cattatcata tattgatcaa
    27721 tccatcggca ggcagcggaa atggctataa agtagcagaa agaattttac cggtattaaa
    27781 aaataagcat attgactata cacttcatta tagtgaatac aaaggacacg atgctgagat
    27841 tgctgaaact ttggcaaaag aaacattgat tccttggata gaagaagaac agaaaacaat
    27901 cgatactttc ccccttttga tcatcgtagg aggtgacggc accttacatc aggtacttga
    27961 tactttctat cagatggaag tagaattccc agttgcttat attccagcag gttctggaga
    28021 tgattttgct cgaggggcag gccttccaaa aaatcccaaa aaaggacttc agctgatttt
    28081 agcagctcaa tcaccagaaa aagtccacat aatggcttat gaagaaaaaa taagtgaaaa
    28141 aaaaggaata gctgttaata atttcggtat aggattagat gcagctatcg tccatgcgac
    28201 aaatcattct tccacaaaaa agcgattgaa caaatacaac ttaggatcat tttcgtattt
    28261 attctctatt ctccgtgctt tattcactca aaaaggattt ccaattctgg tagatgcagg
    28321 aggaaaacaa ttaagttttt caaacgcatt tttatgtaca gcaacgaagc atcctttttt
    28381 tggcggagga atcgcgattg ttccaactgc tgatgcgtct aaaccagtca ttgattttgt
    28441 cgtggtcgaa cgaatcaatt tctttaaaat cttgtggctc attcttttac ttatacagaa
    28501 aaaacaattg aaatcgaaat atttccatca ctacacaaca aacagattac gtatcgtttc
    28561 aacaacaccg caacatggtc aagaagatgg agaagaaatg gaaaaacgac cttttgatat
    28621 cacaataacc acaactaaac agttgttttg gtgttaataa aagaggtttt gtcagaagct
    28681 acatctggaa caccgtttat tcggaaaaaa ggactgtgac acgacttttg tcacagtcct
    28741 ttttttacta tgcagttaat tctttgccca attgggttgc catcgatagt ttctttcttt
    28801 acccaaaata aattggatca ttgaaaacac cgcagcaaaa gcaactaaga cacaaccatt
    28861 gaaccaaaaa gattctgcaa atgtttgatt gtaactgagt gtttcactga tcaagttatt
    28921 attttgaaca aaccaatatg ttggtgtgaa tgccgctatt ttgctaacca tttctggcaa
    28981 gtattctgct ggtacaaaca ccccaccgat aaagcaactg cctgtgataa aaatatcttt
    29041 gatcccaccg ctggtttctg agttttttac caatgaagtg atacaagccg aaaagctaat
    29101 gatcggcaat aaaaacaaga aagtatttaa aatatgatac cataccgtta tatcccacga
    29161 ggtgtggatc actaacagaa ccattagaag taagaagcca ctgaacaaca gcagcgagta
    29221 actaatcaaa ctaaaggtta ctttgcgatt caagtttcgt ttggtaatgg gcgcactctg
    29281 gtttcgttta ctgatctctt tgcgattaaa tgctagattg atgacgctga aaccgctaaa
    29341 aatggataga aacaacccat aagacaagaa attaaaggtt gtgcccgtca acagcttttt
    29401 catccgctga ctatatcccg cacttagctc aacttctcca gtaaccgaga gtgccatttg
    29461 tgtctgttcc atagctgcat cgattgtttt atcttcttct tgaaacagaa tcagtgtttg
    29521 caaaaaggtg ttcacttgct gtgtaacaac tgttttagaa aaggcatctg ggcgactctg
    29581 tatcttgatc gtcggcatct ttcctacttc gacttgttcg gtaaagtctg caggcagatg
    29641 taagataatg tttacacgat taaaataaag agcatcatcg atttcttttt gtgaggttcc
    29701 atccaatgta acgactgttt ccttgtcatt caaatattta cgaaggccat cgactacagg
    29761 cgactcttct tcactaatca aggcgatttt cgcatcttgc agagaggtat tttcaacatc
    29821 aatattttgc gcaaaaaaga atgtggcaac aacagtgata attacaccta tcagtaaatt
    29881 cgatttattt gctttaagca atgtccaaat cgttttataa agcgtcataa cgcacccctc
    29941 tttccatcca agcatttcct aacgcaaaaa ggaaaataaa tccgatcaac catagaagat
    30001 tggtataaaa actagccaaa tcagtgtaga aataaagttt atacaaactt tcgctgatca
    30061 agttgacgag atttaattga ccaacaatcg gaatatgaag atcaatccaa tacttcactt
    30121 gttccgaccc catcatacca gcaaaaaagc tcatcgcaat cgtcactgaa atcaagatgc
    30181 tatccttttg caccagattc atttttggta tcaaattacc aaccaatgta cctaacaaaa
    30241 tcgcacacaa cgaccccaga gcggtaacaa tcatcaacca ttgccaacgt tcaccaaagt
    30301 ctacttgata gataaaacga aagacagcta acataatata aatctctgtc aaaacaatcg
    30361 taaagcttgc tgccaaatta gcgattgaaa ctaacgattg ctttctagga atcaaggaca
    30421 agcgaatacc atttgacgat tgatttgctt gctgatcctg tacattgcgg accccccaca
    30481 tcgtcccgta gagaatcgcc attccaatca gagtgaagaa ataaaaactt ttgaaactca
    30541 tattacgacc tgcatgaact tcttgaaaag atacttcttg ttcaaaaaca gtcatgatgg
    30601 gcgcgagatc aacgttctcc acttctgcca ctttactcga aattatacca atacgctgta
    30661 aaaattgatc catgacgttt ttcatcaacg tctgactcat tcctgcttga cccacatgga
    30721 gcgaaacaga tgaaccatca atgagataaa aaccagccaa atcatctgca tttagctttt
    30781 cattcgcttc tacttccgat agttcctgta cttcaaataa tggtttatca ttgacttcga
    30841 cttgttctaa gactgtggta aaattttccg aaagcgctgt ttgatccgct ttgattacaa
    30901 ttccagtatt aatcgtttcg agattgccac cttgatcaat ctcgccaaag gccgccataa
    30961 acatcaatcc taaaagaatt ggaaaggcca atgtccaaaa caacatggat ttatttcgca
    31021 gcagtatttt tgtgcgatat ttataaaaat gccaaaacat tatttcccct cctctagtct
    31081 ctcaaatcct tgccagtaat ctctaaaaag acatcattca aggacgcttc tttggttgct
    31141 atttttccgt aactgatctt ttcttcttgt aagattgtaa gaatcggcaa caatactgta
    31201 tttagttcag tagttgttac ttggagctga ccttttttat aagcgattcc atcagaagct
    31261 attgttcgct gacaacacgt tttctgggag taatgggatg tcgatcgtca aacgatccgc
    31321 cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct gtccttgatc
    31381 catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg ttgtatagac
    31441 aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat tccgactttg
    31501 ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt gggcaatccc
    31561 acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac gaaacgaaac
    31621 atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc ttttctcttt
    31681 ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta gttcgtcaaa
    31741 gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat tttcaggagt
    31801 cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag aaagcataca
    31861 gttgatggca gtcgatttcc cactgccgtt tggtcctaac agacctaaga cttctccttc
    31921 ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt tgactaattt
    31981 atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat ctgactataa
    32041 taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca tttgtcacaa
    32101 tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt ctactggtta
    32161 tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc tatttattga
    32221 tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat tggattttcc
    32281 aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt ctgccagcga
    32341 cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg ttaggttttt
    32401 tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc gtaattttgc
    32461 tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt gagaaaaagt
    32521 acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa caaaataaag
    32581 cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa cggaaccgaa
    32641 ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt ttacaaattg
    32701 gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa aatttaagtg
    32761 ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc catgagacat
    32821 cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct tctgttacga
    32881 ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc ttaatggtca
    32941 tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt gttttacatt
    33001 ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc agcccacaaa
    33061 aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa gaacaaaagg
    33121 gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt ttaccaaggg
    33181 agggacacca atgataacag tagtcattat tgagatgatc catttgtgac gaaatcgtta
    33241 caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca ttgtgccaag
    33301 gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga catccgcatg
    33361 cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc
    33421 cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt
    33481 gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct
    33541 tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag
    33601 aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc
    33661 atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt
    33721 gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc
    33781 acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa
    33841 cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc
    33901 gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg
    33961 gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg
    34021 attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca
    34081 tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt
    34141 cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca tatcacactg
    34201 aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc
    34261 aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat
    34321 ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt
    34381 ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt
    34441 ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt
    34501 ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag
    34561 aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga
    34621 tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg
    34681 cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca
    34741 aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt
    34801 cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt
    34861 ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc actttatctt
    34921 cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg aatacattca
    34981 attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc
    35041 aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta
    35101 acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac
    35161 ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca atttgataag
    35221 catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc
    35281 cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct
    35341 gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag
    35401 gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa
    35461 tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca
    35521 aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc
    35581 ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg
    35641 ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat
    35701 ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt
    35761 tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag
    35821 cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct
    35881 tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg
    35941 aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt
    36001 gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga
    36061 tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg
    36121 gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc
    36181 gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt
    36241 tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca
    36301 aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac
    36361 gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca
    36421 tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga
    36481 ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga
    36541 ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt
    36601 cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc
    36661 cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct
    36721 ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat
    36781 tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg
    36841 gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct
    36901 aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca
    36961 gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc
    37021 tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa
    37081 agtgggccat ctttatgttg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt
    37141 gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc
    37201 aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa
    37261 gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc
    37321 tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct
    37381 ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta actttgtggc
    37441 aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc
    37501 ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact
    37561 ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta
    37621 gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc
    37681 aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc
    37741 ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca
    37801 tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta
    37861 cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca
    37921 ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc
    37981 tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt
    38041 gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt
    38101 atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg
    38161 tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca
    38221 ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt
    38281 ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa
    38341 taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg
    38401 ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg
    38461 tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt
    38521 ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg
    38581 acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga
    38641 gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa ccgcgttgaa
    38701 tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga
    38761 ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat
    38821 ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag
    38881 cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga
    38941 ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg
    39001 ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat
    39061 caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg
    39121 attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt
    39181 ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc
    39241 tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac
    39301 tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac
    39361 ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct
    39421 ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat
    39481 aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg
    39541 gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa
    39601 ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt
    39661 cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc
    39721 ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa
    39781 ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag
    39841 aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg
    39901 gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc
    39961 aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa
    40021 tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat
    40081 caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga
    40141 ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac
    40201 ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt
    40261 cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa
    40321 cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga
    40381 agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg
    40441 tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta
    40501 ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag
    40561 cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat
    40621 cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt
    40681 cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg
    40741 cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt
    40801 gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt
    40861 acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg
    40921 cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg
    40981 acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag
    41041 cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta
    41101 ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt
    41161 taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt
    41221 gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt
    41281 cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac
    41341 caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa
    41401 aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca
    41461 atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag
    41521 cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag
    41581 ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc
    41641 cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg
    41701 caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata
    41761 ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg
    41821 ctttgcaaaa agcatcaaac cagatgtatc ccgatctagt cgcgtcacca catggattac
    41881 ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt
    41941 tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg
    42001 ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc
    42061 ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc
    42121 tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt
    42181 tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc
    42241 ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat
    42301 gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc
    42361 ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt
    42421 ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa
    42481 acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga
    42541 tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca
    42601 atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg
    42661 tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt
    42721 catccaaata actgatccga acatccagca agggataact aacactttgt tcccggttcg
    42781 ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta
    42841 aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga
    42901 acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat
    42961 ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct
    43021 ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct
    43081 ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac
    43141 cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca
    43201 gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta
    43261 taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt
    43321 tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga
    43381 taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc
    43441 atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac
    43501 atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc
    43561 cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt gacaaattca
    43621 atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc
    43681 aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct
    43741 gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt
    43801 actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc
    43861 gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac
    43921 gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt
    43981 tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc
    44041 gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca
    44101 acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt
    44161 tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa
    44221 accggaaagc ttacaacaaa acgggctgaa ttccctattg aagaaggact tttagctatt
    44281 gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca
    44341 tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct
    44401 gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca
    44461 aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta
    44521 gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt
    44581 gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa
    44641 gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat
    44701 ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa
    44761 cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt
    44821 caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat
    44881 gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg
    44941 aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa
    45001 aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc
    45061 tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc
    45121 acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat
    45181 acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc taattaaaaa
    45241 aatacgtcga ctcccttaca agagagccga cgtatttttt tcgtttctat tcgagaaaat
    45301 caaaaataga aagccttata aacgatcgat caattcttct aattcattta gacgttgttc
    45361 aaacatcgac attgcatctt caatatatgc agcctgtgtc atatcaactc ctgctttttt
    45421 cattacttcc acaggataat cgctgttacc tgcttttagg taagccaagt agttctctag
    45481 tgcctctggt tcctggttta gtattttctt cgccagtgct gaagcagcag aaaagccagt
    45541 cgagtattgg aaaacatagt aattataata aaaatgcggt atccgtgacc attcgaattt
    45601 aatttctggg tcttcttcga ctgctggacc ataatatttt gcattcaatt taccataact
    45661 atcacttagg tattcactag tcaatggcac acctttttca tcttccgtat gcatgaaatg
    45721 ctcgaattca gcgaattgtg tctggcggaa aactgttcct ttaaacccat ccaagtaatg
    45781 gttgagtaca taagcccgta cacgagggtc tttttctgtt tccaataaat actccgttag
    45841 gatattttca ttcgttgtcg aagcaatttc tgctaaaaag atggagtagt cgccgtacac
    45901 ataaggctgg ttcgaacgag tgaaataact atgaacacta tgtcccattt cgtggacaag
    45961 cgtaaatagc tgatccagcg tatcatgcca attcaataaa atatatggat ttgtgtcata
    46021 gcttcccgaa gaataagcat cgcttcgttt ccctttattt tcgacaacat cgatccaacg
    46081 ttcagagaat gctttttcta cgatggccat gtattcttca cccattggtt tcagtgcttc
    46141 taaagctttt tcttttgctt cttcgtacgt aaaggtaatt ggagcttccc ctaagaccgg
    46201 tgtataaaga tcatacatgt gcagtttttc cacttctaat aaacgtttcc gtaattccat
    46261 gtatcgatgt aacaaaggca aatgcttgtt taccacgtct accaaagtat cgtatacact
    46321 ttcaggaata tgattattgc tcaaagacgc ttctctggca gagctgtaat tacggacttt
    46381 cgctttaaaa ttatgtcctt ttatatgtgt gcctaaagta gaagcaaatg tatttctaaa
    46441 ttgttcgtaa acactgtaca atcccttaaa tgctgcttcg cgcacccttc gatccgtgct
    46501 ttctagcaac tgaccataca cgccatgaga taattggact atttcaccat tttctccttc
    46561 aatcgttgga aaaactagat ctgcattatt caaaacagca aatgtatcac ttgaagcatc
    46621 aaagatttca cctgctccag caagaagaga ttcctgctca gcagataaga catgggctcg
    46681 attatctact atttgctgga tataatggcg atagacttcc aattttggtt cttctttgaa
    46741 atattgccaa atctggtcat ctgacaattg caatatttct ggttcaaacc aggaaacggc
    46801 ttcactaact ttcgaaaaca gactgcttgc tcttgcataa agcgcttggt aatctgtatt
    46861 tccagtgtct tgatcgtttt taaggtgcgc atatacataa atgacttcag tttggcgata
    46921 aaccctcaat acgaattcaa tcgcatttaa aaattgagaa gcgccttgat caagtgttcc
    46981 tttgtgtttt tcagattgtt ttaactcttc tgataattcc aaatatttct catcaaactc
    47041 ttggtcgctt gaaaagatct tggtcaagtc ccaagttaaa ttttcaggca attcttctcg
    47101 ttttggcaac tgctttactt ccatgaaatc cactcctttt cttcccttag ctctatctat
    47161 caaaatagat catagtctaa catccacatg tcacagcatc taacttttct actcattcat
    47221 gtgtctgctt ccatcaattt tagcataact aaatcttgtt ttacatagaa aaccgattcc
    47281 tagcctattt ttatacttac tattttttca aagaagacaa gtgtatgcat tcgttaaaaa
    47341 actgctgata gaccatctct tcatcaatca taggaaaaag ccattccctt ttatgttctt
    47401 ttatttggca aagccatgag ttgaaatcag gaactttctg gttttccaag gcttcttcgt
    47461 acaacattcg ataaagaaaa acctgttctt gtaaataaaa gaaaaaccga cttttttgat
    47521 agatccacga tgatagatgc aaaagatgtt tatgacgcaa gtagcattgt tcttgtatgg
    47581 atactgtatt cttttgcttg tgaataagtt ggcgtgtcag ccatttcttc ccatcttcac
    47641 tcactttttc tatttttttc atttggttca ttttaatttc gttactagtg aatatttctt
    47701 taaggtccct actagaaaaa gtccagcagc tactgcaaaa ggaaatatgc cctgatacag
    47761 tctctgtaat atgatgatac aaataaagct tttgtttctt gagatcagct ttccagcaat
    47821 gcactcctct ttttctatta tagtagcagc aacttttttc tatcaatgag aattgcgatt
    47881 gtccaagaaa agaattacca agtatccacc atacttggta actgttattc aaataatttt
    47941 gggttctttc aataaatctc tggtgagaca gtctagaaca ttggatttct attgctagat
    48001 tcgccaacaa aatatccggc ctttgccgca acctcggcaa ataggcttcc aaaaatactg
    48061 gttctactga ctgtcccagc caatccatga agcattcctt taactgtaag tgctcttttg
    48121 attctctttc actaaagacc gaacagttat ctgatttttg atgggcaaaa tgagcacatt
    48181 ttttctttcc ctttttcaaa atcactcttt ttcgacagcc acgacaataa tatttctttc
    48241 ctttttctgc atgtttagca aaacagcact tattatattc attcattgca agcagcattt
    48301 ttctccctct gaacttattt acgtctaaga atttatttac acgaaaaaag agggcgtgaa
    48361 aaagctattc tgcatcaagt aataagaaca gctaaacaaa aatagttccc aatatttttc
    48421 gtttggttgg gcttgttacc gcagatgcaa gcttttgaac acatttatac gaaaaaaaga
    48481 ctgcgacaca atttttgtca cagtctctta ctataatgct gatttataca aaataaaatt
    48541 tcgttcgctc gatagcatta cgcgccatca gacattgtcc atattcattc aatgtttctg
    48601 gtgtacgatc gctcttttca gcaaactcca aaattcgagc aatctgattc tctacatccg
    48661 cttggttgag attttccatc cagaagtgaa cgactaggta atagcgctct tcgaataaat
    48721 acaaatcagt ccaagcagac tctagttcga catctgttgc aagttggatc acttgttcaa
    48781 aatcttcaaa agcaaaagtt gcttgtcttt cctgttcttc tagggcgctt ccagataatt
    48841 cttcctccgg atcgctgcca ataatctgct gacgaagaaa gtcactcaca tcttctgaat
    48901 caacagtaga atcttctgat tgagaaattt cttcatccgg aagattttta ctgataaaca
    48961 gttctaatcc gtctcctttt ggcaaaactt ggaaagtgac agcttcgctt cctcggaact
    49021 cctcttcgat atcaacttct tccaaaatac tataaaagaa attttcgatt tctttgtgat
    49081 tgccaagtaa atccaaaaat gaaacgcccc gttcctctaa atcttcatga ccaattagta
    49141 cacggatcgt attttcatta atatgttcca tttccatttt gctacacctc actttgccac
    49201 aatgtttaat atagattcat tgtagcgaaa tcagcttaaa tgtaaagaaa aaaaatctcg
    49261 ctgttaagcg aatttaataa aaccagcgga tttttcaacc tttcaagcta tcttatttaa
    49321 ctataacatt tttggcagac gaatactata tagccgactt ttcagctaat tttccctctc
    49381 tatttttcgt gcaatcatca tcttctacta cctttttata catctaatca agaatacttt
    49441 ttgtaaaaac aaaaaaactt ggaaaaacta tctttgtaat agt
//
LOCUS       DAXLPC010000008        48965 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.008, whole genome shotgun sequence.
ACCESSION   DAXLPC010000008 DAXLPC010000000
VERSION     DAXLPC010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48965
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.008"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            591..1280
                     /locus_tag="ACF3UE_000465"
     CDS             591..1280
                     /locus_tag="ACF3UE_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3633922.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="ACF3UE_000466"
     CDS             1267..2475
                     /locus_tag="ACF3UE_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFD3633923.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="ACF3UE_000467"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="ACF3UE_000467"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFD3633924.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACF3UE_000468"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACF3UE_000468"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFD3633925.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="ACF3UE_000469"
     CDS             complement(6578..7273)
                     /locus_tag="ACF3UE_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFD3633926.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACF3UE_000470"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACF3UE_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFD3633927.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="ACF3UE_000471"
     CDS             complement(8472..8663)
                     /locus_tag="ACF3UE_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFD3633928.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="ACF3UE_000472"
     CDS             complement(8684..9574)
                     /locus_tag="ACF3UE_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFD3633929.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="ACF3UE_000473"
     CDS             complement(9561..10328)
                     /locus_tag="ACF3UE_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFD3633930.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACF3UE_000474"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACF3UE_000474"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFD3633931.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACF3UE_000475"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACF3UE_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFD3633932.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACF3UE_000476"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACF3UE_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFD3633933.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="ACF3UE_000477"
     CDS             14899..15282
                     /locus_tag="ACF3UE_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633934.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACF3UE_000478"
     CDS             complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACF3UE_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFD3633935.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="ACF3UE_000479"
     CDS             complement(16226..17044)
                     /locus_tag="ACF3UE_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFD3633936.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACF3UE_000480"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACF3UE_000480"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFD3633937.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACF3UE_000481"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACF3UE_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFD3633938.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="ACF3UE_000482"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="ACF3UE_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFD3633939.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="ACF3UE_000483"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="ACF3UE_000483"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFD3633940.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="ACF3UE_000484"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="ACF3UE_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFD3633941.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="ACF3UE_000485"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="ACF3UE_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFD3633942.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="ACF3UE_000486"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="ACF3UE_000486"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFD3633943.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="ACF3UE_000487"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="ACF3UE_000487"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFD3633944.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /gene="rpsF"
                     /locus_tag="ACF3UE_000488"
     CDS             27086..27385
                     /gene="rpsF"
                     /locus_tag="ACF3UE_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFD3633945.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="ACF3UE_000489"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="ACF3UE_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFD3633946.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /gene="rpsR"
                     /locus_tag="ACF3UE_000490"
     CDS             27973..28209
                     /gene="rpsR"
                     /locus_tag="ACF3UE_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFD3633947.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="ACF3UE_000491"
     CDS             28352..30325
                     /locus_tag="ACF3UE_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFD3633948.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="ACF3UE_000492"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="ACF3UE_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFD3633949.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="ACF3UE_000493"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="ACF3UE_000493"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFD3633950.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="ACF3UE_000494"
     CDS             33204..34496
                     /locus_tag="ACF3UE_000494"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFD3633951.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35283..36146
                     /locus_tag="ACF3UE_000495"
     CDS             35283..36146
                     /locus_tag="ACF3UE_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD3633952.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36275..37897)
                     /locus_tag="ACF3UE_000496"
     CDS             complement(36275..37897)
                     /locus_tag="ACF3UE_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD3633953.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38146..38667
                     /locus_tag="ACF3UE_000497"
     CDS             38146..38667
                     /locus_tag="ACF3UE_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFD3633954.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSVLTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38853..40583)
                     /gene="spxB"
                     /locus_tag="ACF3UE_000498"
     CDS             complement(38853..40583)
                     /gene="spxB"
                     /locus_tag="ACF3UE_000498"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFD3633955.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40748..41566
                     /locus_tag="ACF3UE_000499"
     CDS             40748..41566
                     /locus_tag="ACF3UE_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFD3633956.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41669..41866)
                     /locus_tag="ACF3UE_000500"
     CDS             complement(41669..41866)
                     /locus_tag="ACF3UE_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633957.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            42035..42613
                     /locus_tag="ACF3UE_000501"
     CDS             42035..42613
                     /locus_tag="ACF3UE_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFD3633958.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42708..42845
                     /locus_tag="ACF3UE_000502"
     CDS             42708..42845
                     /locus_tag="ACF3UE_000502"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633959.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43658..44161)
                     /locus_tag="ACF3UE_000503"
     CDS             complement(43658..44161)
                     /locus_tag="ACF3UE_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFD3633960.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44520..45545
                     /locus_tag="ACF3UE_000504"
     CDS             44520..45545
                     /locus_tag="ACF3UE_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFD3633961.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45868..46746
                     /locus_tag="ACF3UE_000505"
     CDS             45868..46746
                     /locus_tag="ACF3UE_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HFD3633962.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47222..47338
                     /locus_tag="ACF3UE_000506"
     CDS             47222..47338
                     /locus_tag="ACF3UE_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFD3633963.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48266..48604
                     /locus_tag="ACF3UE_000507"
     CDS             48266..48604
                     /locus_tag="ACF3UE_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3633964.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48698..48928
                     /locus_tag="ACF3UE_000508"
     CDS             48698..48928
                     /locus_tag="ACF3UE_000508"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFD3633965.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
BASE COUNT        15099 a         9137 c         9593 g        15136 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagat caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgtaaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggatcaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggtggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccggc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagacatt gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atggggaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatcc
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaatcct tgaaaactat
    25441 atcgaacatc aacgcgaagt catcacacga cggacggtct ttgaaaaaga aaaagcagaa
    25501 gcaagagcac acatcttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaggcaaaag caacaatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgtacagc caaaggaatc ccaatcatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggtcagagg gatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aaaatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaataa ccatcaagac taagtgtgta agctagcaag
    26881 aataaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataattag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattagatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaat gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atattgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaagagg tagtgaaaga gacgtttagc cttattgccg ataggctgtc
    34621 tcttgaacac tgtttattca gaataaggga ctgtgacaaa aaccgtgtca cagtcccttt
    34681 ttccgaacaa acggtgttca aaagcttgca tctacggcac taagcccaat cagatgaaaa
    34741 atatggagtg ctatttttat ctgattgttc ttactgcttg atgcagagca gctttttcac
    34801 aacctctcca ctaaacggtg ttctcctgcc aactcctcgg tcacaagtca caatattcaa
    34861 caaacatgag aagctgtttt ttgaaattgt tccttgtgac tcggagctaa acggcaggct
    34921 cacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct caaaaaacgg
    34981 caaaatatga ggaactattt tttccgtttt tttctctaat actcaggtca aaacgctgat
    35041 ttcacaacct ctgattcacg gtgttccaga agtagcttct acggaaataa gccgaaattt
    35101 cacaaaaatt tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag ctgaccactt
    35161 ctgtcacaac ctcttatttt gattagaact tgcgaaaata aaccggttaa agtgtgtcta
    35221 gcgcaagaga tttgctataa tagacgataa gggtaaaatg taacgagaag gggttgaaaa
    35281 atgtgtatca aattgtaaca gattcttgtt gtgatctgcc ataccatgta ttagcaaaag
    35341 aaaaagttga ttttttatca atgaatctcc aattgaatga tcaagagtta gtagatgacc
    35401 tcggaaagac attcaattat gaccgctaca tgaatcagct gaaaaatggt gcgatgccta
    35461 cgacatcaca aatcaatgtt ggccgatatt tagaattttt ccgttcttat gcggaaaaac
    35521 agattcctgt tttatatgtg gctttttcca gtggattaag cggctcttac agtagtgcgc
    35581 ttcaagcggt tgaattgctg aaggaagaat atgaagaccc tgagatctat gtttttgata
    35641 caaaagctgc aagtattggg gaagggcttt tagtattgga agctgtaaga ttgaaaaaag
    35701 aaggtaaaag catcgaagaa accctagagt ggctggaaag taattatttg aaagtccatt
    35761 catgggtaac agtagacgat ctgaaatatc tagaacgagg cggtaggatt tccaaagcaa
    35821 gtgctactct tggcagtcta ttgagtgtaa agcctattat tacggtggat aaagaaggaa
    35881 ggctgacgaa tgttgacaaa gttcgaggaa gaaacaagtc gatccagaca atcgtcaatg
    35941 agacggtaaa aacaatcgtt gcaccacttg atcaaatcgt ttatgtggct tacgctgggg
    36001 atctagagag cgcggagaag gcaaaacggc ttttggaaga gcagataaag atgaaagatg
    36061 tgaagcttta tcccttagga ccaacgatcg ccagtcacac aggctatggc tgtatcgcga
    36121 ttttttcgat gggaatcagt cgataaaagc agtaactcat tctgtaaaaa agcccagaaa
    36181 ttgattgtaa caaaaacagc gactcttaaa agatagatga gcatcctatc tcttagaggt
    36241 cgctgttttt ttatttttta agctaaatag gccattatgc ccataactcg ttcaattgtt
    36301 tttgaatatc tgcattttcc aaaaattcat catatgtcgt atcagctcga tcgatcacac
    36361 ctttatccga aacggcaatg atgcggtttg ccaatgtttg gataaattga tggtcatgtg
    36421 acgcaaataa gattgagcca gtaaatgcca tcaagccgtc attcaatgct gtgattgatt
    36481 ctaagtctaa atggttcgtt ggatcatcta atacaagtac gttagctttc gaaagcatca
    36541 tttttgaaag catgcaacgg actttctctc caccagataa aacattcact ggtttcaata
    36601 cttcttcacc agaaaacaac attcttccta agaagcttct taagaaggtg ttatcatctt
    36661 cttctttact tgcatattga cgcaaccagt ctaaaatcgt tagatcagta tcgaattctt
    36721 tcgttgtatc ctttggtaaa taagaattac ttgttgtcac accccaacgt actgttccag
    36781 tatctggcgt aatttcaccc atgataactt tgaatagcgt tgttgttgtt atatcatttt
    36841 ctgcgacgaa agcgaccttg tcttctttgc tcaaattaaa agatatatca tctaaaattt
    36901 tctttccatc aatcgttaca cttacatttt ctacctgcaa taagtcgttt ccaatctcac
    36961 gttcaggttt gaatccaacg aatggataac gtctagaaga aggttggata tcgtctaaag
    37021 taattttttc aagcattttt ttacgtgaag ttgcttgttt tgattttgat gcattcgcac
    37081 taaagcgggc aataaattct tggagttctt tgatttgttc ttcttttttg gcatttgcgt
    37141 ttgcttgaag tttagccgct agttgactag attccaacca aaaatcataa tttcctacat
    37201 aaagtttgat tttaccaaaa tctagatccg ccatatgtgt acatactttg ttcaaaaagt
    37261 gacggtcatg ggatacaacg atcacagtat tttcaaaatt gatcaaaaat tcttccagcc
    37321 aattgatcga ttggatatcc agaccgtttg ttggttcgtc tagcaaaaga acatcaggtt
    37381 taccaaatag tgtttgtgct aataacactt ttaccttttg tccaccagtt aattcactca
    37441 tttgctgatg gtgcaattct tcagggatgt tcagaccttg cagtaaaaca gctgcttctg
    37501 gttcagcttc ccatccatta agctcagcaa attctccttc taattcagct gctcgaatac
    37561 catcttcgtc agtgaaatcc tctttcatgt aaatcgcatc tttttctttc agcacttcat
    37621 acagacgctt gtgtcccatg atgactgttt caagtacagt atagtcttca tagtcgtaat
    37681 ggttctgttt caatacggcc atccgttcat ctggtcccat agtaacggaa cctgtggaag
    37741 gctgcagatc ccctgataac actttaagga acgttgattt acctgcacca tttgcaccaa
    37801 tcaagccata gcagtttccg ggggtaaatt taatattcac atcatcaaat agtttgcggt
    37861 ctgaaaagtg caaactcaca tcatttacag taatcaattt ttttcctcac ttttatcatt
    37921 attagttttg acaagtctta tagaattata taggggaaag gtaaaagatt caaggcaatc
    37981 gaacattctt tgtgtttcac gtgaaacaga atgaaaaaaa taaaaataaa agcggagcga
    38041 aaatagctac tataggattt attagtttgc aacagcataa tttttgacgt tatttataag
    38101 agggagtact ataaaactgt aaaagaaatg aaagaaggat tgaaaatgga tgaaaaaaga
    38161 accatcgact ggggctcatt gattttggga attttatttg tacttgtctc attgttatca
    38221 tttcaagacc ctgtcggaaa tttagttgca attgtagtag tctttgcgat ttttgccttt
    38281 attaaaggga tatttgaact gtttgtacgg aacagattaa aagagctaac aggatataaa
    38341 ggaaagatgc ccttaataat cgggatcatc gatattctag ttggcgtctt tttcttattc
    38401 aatattggtg caggagtcgc agcattgcct tttgtttttg cagtatggtt tattgctgat
    38461 tcagttttag cgttatttac tgctgacttg gcaagaggag taagtgaagg atattattgg
    38521 tttacgatca tcgtcaatat tttaggaatt ttattaggaa ttttcttatt gtttaatcca
    38581 atttcttctg tgttgacatt aagcttttta gttggattct attttatgtt atttggtatc
    38641 acacatatcg tctatgcatt tagataagta aaatcaaaca aataaaaaag ccggcttccg
    38701 attacagttt tactgttgta attggaagcc ggctttttta tcatggacaa atatgcacga
    38761 ggtgattttt aggtgtcgag acaaatttat gcaaaaatgt gagaagctat atacacaaat
    38821 tttatcttaa tactcgaagc atagcgcagt tgtcacaacc tcttttcata taattcattc
    38881 aatactggca aatcatggac ttcatatttt tctttgaatg cttggatttc ttcttcagaa
    38941 tattttcttg gatctaaatg cagatcttct actggcaatg ggcgcttgtt attgatcttc
    39001 acatcgatta ctacaggacg atctgatttt gcagctgcat caaaggcaaa tcgaagttgc
    39061 gagtattctg tgactgtaaa gctatttgcc ccgagcgctt ctccaacttt accgaaatct
    39121 gcatcttcta aaaatacacc aaatttcttt tgttccgtat cttcttgttc tgcttcgatg
    39181 aaaccaaaag aatcattcga aaagacaaca ttaataattg gaagctgata tttgacttgt
    39241 gtaatgatat cttgcatgac catagcaaac ccgccatcac cacttaaggt aaatacttgt
    39301 ttttctgggt agcttagttg tgcggcaatt cctcctggca caccattacc catagttgcg
    39361 aaccatccag atgtcgtatg tttttgttta ccgttcatat tcaataaacg aatagaatgg
    39421 atagtcgtgt taccgacatc tgtgacgaaa atcgcatcgt cttcagcaat acgattgatt
    39481 tctttataga cagcctctgg acgaatcggt tcttcctctc gatcttcaaa agatttcaac
    39541 caatttaccc atttttcttt attttcttga tttgctaggt accagctatc agcagggcga
    39601 gcatccccta actcgacaag tctttgcaaa gctgtgtttg catcaccgag gatcgacaaa
    39661 gatgtttcat ggcgtcgtcc aaattttgac gcatcgatat cgatttggat aaattcagca
    39721 gttggattaa aaaatgcacg tccaaatggg aagtcgctac cgacaaataa gatcagatcg
    39781 gcttctgcca atgcttcatt tccgggttta gtagcgacac gtccagcaaa accaagaaag
    39841 ttttcataat catcaggaat aattcctttt gctagaacgg aagcgacaac aggaactgaa
    39901 aaatgttctg agaattcttt gatttgcgga aatccgtttc gcgttccttg accaacataa
    39961 agaactggtt tttttgcttt ttcaagataa ggcaaagcag ctagcaaatc tttttcttct
    40021 ggtaatatca cacttgtttt gtgagtgtga gcggtggaga aaggttgttc gtcaatttct
    40081 tcaaaaccaa gatcaacagg gatagtcacg atagccacgc ctttatgctc ataggcggct
    40141 ttaatggctt catctactac atgcggaaga ctttgtggtg tcatgactgt acgattgtat
    40201 acgctaacat ctgcgaaaat aggattttca tttagttcct ggaaagagtt atagttcatg
    40261 gatgtagaag caacttgtcc taagaacgct actagaggca catggtccat ctgtgcatca
    40321 tacaaaccat tgatcaaatg tgtcgcacca ggtcctgcag agccgaagac agcgccgact
    40381 ttccccgtta attttgcatc tgcagcggct gcgagtgcgc cgacttcttc atgacgaact
    40441 tgaatgtagt tgatttcggt tttttcttga tatagcgcat ccataattga attgaaagat
    40501 cctccgggaa tgccgtaaat atggtcgata ccccagcttt caagaacttt taccattgcg
    40561 attcctgcat tgatttttga catggtgttt cactccttta gcaatgatga tacataaatt
    40621 ttttgtatct agagtataga actttttatc gaaaatccca actaattcgt cttttcacaa
    40681 aaatgtagtc atgtttttgg gaatatgcta gagtagtaca tagatagatt caagagaggg
    40741 gaatggcatg gttgaatggc tattgagact tgaaccttgg cagcaagcac ttgctgggac
    40801 agcttttact tattttatga cagctcttgg tgccgggttg gtttttttct ttaaagaaat
    40861 caaaaaagaa gtgctaaact tgatgttagg atttgcttct ggtgtcatga ttgctgcaag
    40921 tttttggtct ttgttagatc cggctattac aaaagcagaa gaaaatggag atattgcttg
    40981 gctagttgta agtattgggt ttggtttagg cggtgtgttt ttatatatgg cagataaaac
    41041 actgccccat atgcattttg gaccacaaca tgaagcagaa ggattgccta cccatttaaa
    41101 acggacgatc ttgcttgttt tttctattac attgcataac attcctgaag gtttagccgt
    41161 gggggtagca ttcggtgcag cagcaactgc ggataatccg acagccgcta tattagccgc
    41221 tgtttcggtg gcgctaggta ttggtatcca aaacttccca gaaggagcag ctgtatcaat
    41281 cccgttgcga caagaaggtc tgagtcgtaa aaaggccttt gtttacggac aagcttctgg
    41341 aatcgttgaa ccaattgctg gagtgattgg agcgctacta gtaacgaaag tggagctgct
    41401 gcttccttat gcacttgctt ttgccgcagg agcaatgatt tatgtcgtgg tggaagaatt
    41461 gatccctgaa gcacagcaga cattgtccag caaacgtcat tttgcagttt ttggcgtcat
    41521 gagtggattt atcattatga tgattttgga tgtggcatta ggataaataa aaaaaatata
    41581 tatgatatat caaatagggc cgcgaactta tatcgcgacc ctattttttt agtaagttat
    41641 atcataatga agtgaatggt atcatacatt aataatagtt ttttctatgt gtatttcctt
    41701 tgatccagcg aacaagccag atgataagtg cgattgggat tagaactttg accgcaaacc
    41761 ataaaagccc gcttaggaca ctgacaaaaa gactgatgac gaagctagct gcaattagca
    41821 ctaaaagaac catgaagata tttaagaaca tatttttttg acgcatacaa aaccctcctc
    41881 ttgttcattc tttactatag aaaaagtata acagggattg tttaaaaaca cctccaactg
    41941 aagactgatt tttacttcat ctacttaaat gatcaaacaa ttgctttttc tctggtttat
    42001 catctaaaat agagcggaaa aggaggagaa tatcatgcct aaaaatcgtc ttgaagcatt
    42061 tacagatgct gtaatcgcga ttatcatgac tattttagtt ttagaacttc atgaacctaa
    42121 cggagacacg tgggaggcgc tcgctgcatt aggttaccga ttttttatct atattgtcag
    42181 ttttatcatt ttagcgattt attggaacaa tcatcatcat ttatttcaag ttgtacataa
    42241 gataaatgga cgggtcttat gggcgaacag tttctttgtt tttgcgcttt cgctttttcc
    42301 gtttgcaact tcatggatca gtgagtacat caatagcctg gctccagaaa tgacttatgg
    42361 ttttgttacc ttgaccgcta atattgcgta ttatatcttg gcaaaagaac ttgtcaaagc
    42421 aaataaaggc cacgagaaag cattgaaggc gatgttgaat aattacaaga aatcgtatct
    42481 atcgattggt ttgaatgtgt taggaattgt cttagggtat ttagtagcgc cagtagccgt
    42541 gctgatcgca aacatcgtga ttctagctgc ttggatcatc ccaagtcgta ccatcgaatc
    42601 acaatatcgg taaaatgatc cgtgtttaaa atttaagaga aaaatataga aaaaataaat
    42661 aaacgatcaa atatccgagt gatactagta ttcaaagagg gatgcagatg gatcaaaaaa
    42721 gaattcatgt aggactgatt actagttttg tcacgatgct tatttatttg gatcaaggtc
    42781 atttgacttg gacagtagtt ggtgtcgtag gatttttgac attattcaca gcaataaaaa
    42841 aataaacatc tttatgtaat ctgatgttct atctatttaa gaaaagcatg tttacagcag
    42901 tatgattctg ttgtaaacgt gtttttattt gtggaaaatt taatttttag aaaagtgtat
    42961 cgaaaaatag atagttagtt tttccacagt ggataacttc gtaagagata aaaataaaaa
    43021 attagtcaaa gaagggcgta tagatttctt ttgataggag atatacaaca gaaatgaata
    43081 aatattaacg tgttttcaaa cagtataaaa cggtgtggtt tttggaataa aaaaataaca
    43141 tatctcattt tacacttttg ttattttata cttaaaaaat aacgacacag aaaataccgt
    43201 gtctcagatt tctctactac ttctaaaaac tactgttttt ttcctttgaa atgccttcaa
    43261 aaagtaggat caggcagaat atactggcag aatcaaggag aagggagcct aaataaggag
    43321 aaaaaccata gaaaatataa agtaattact tataaaacaa gctttttata gaaaaataat
    43381 atacctgagt agggtataaa ttaagacgga attcctttct agattgagat attgactagg
    43441 aagaatgtta agattttaag cctttaagct aaaaaaaaac cctttttgtt aaataagggg
    43501 aatatagcct gtcagtttca aactgcaagt cgtcctgctg caataatata gtagattaga
    43561 gatgaaaata gattttttta aaccaatgac tgaataaaaa gaccgtcata gatacacatt
    43621 ggaatgtgtc tattacggtc tttttttacg aacgatttta ttgaagacgg acagttcggg
    43681 tcaaaaataa aaaagctacg atcagaaata agaataaaat gtatcccaaa ataatggcta
    43741 gacggtctaa cttatttgtc gatagatgtt tgtttagaag ttgataggcc cataaaccta
    43801 tcagtcctcc tgttgtatta gttatcaaat cagtgatgtc cgctacgcca ataccgaata
    43861 ggaattgaat caattctgcc aagaagctta caaggaaaat aatccctaat tttttagaaa
    43921 aagaaagtct cttgaaattg acattcaaaa gcaccccaaa aggaaaaaag acaatcaagt
    43981 tataagtggt ctcacgtaat accgtcgtat tttcaaaaga aaaagtagaa aaagggacga
    44041 gattgacatt gctgtaagaa taagtgagaa attgtggaag attaaatgat agcttgaata
    44101 aaatcaacca taatagaaag aataaataaa tccctaataa aaattttgat acataccgca
    44161 tagacatctc ctccatttaa aaagtatacc atcgaaaacc gctgaaaaat cataaaaaag
    44221 tatgaagttt aaggaccaac gtagttatcg tacgaaaatt agaagctttt ttttgttggg
    44281 aatccggttt ctttaacaaa gctaagatag cgagttgctt ggaaaagttg ctatcttttt
    44341 tctgtcaaaa cgactcggaa tgttcgtttt ttgttctaat ttctccaagt tgtttacttt
    44401 ttgatactaa gtttatgaaa aatcaagaaa tagttgttat actaggtaat gctgacaaac
    44461 gggattggca tttcatcttg gttcagcttt ttttccaatt actaggaagg agggatagat
    44521 tgttcaagac ttattttcgt ttcaataaaa tacaagataa tccttttcgt atcatgaatc
    44581 tgatgctact tatctttatt gtattatggt taggttacat aaatcatgat tttttgattt
    44641 caagtttttc atcattaggg atctttactt ttttctatta tcaaaacata ccgatgaaat
    44701 atttgctgaa acgtatgttt ctgatcggtt gcggactgtt ggttgctttc gttttgggga
    44761 tcttatcgac ttatgtttta tggcttgaac catttgccgt agctttggtt gctttttcca
    44821 gcagattcgt gttgcgatta ttccatattt ctaaaccagg tggcttgttt tttgcgatgc
    44881 tttctgccat gggaacgagc atgcagctgc caatcgctca attaccgatc gtctcacttt
    44941 atttttttat gggtgtcgtt tttgccctga ttgcggcagt gattacaaaa ttactggatt
    45001 cacggcctga gcagacaatt gaaaaagcaa ctttaaaaga aagatttcac gaagagcctt
    45061 tagtgatcat tgattctgtt ttctacagcg ctgccttatt tctttccgtt tatgtcagtc
    45121 acggcttgaa tctgcataat ccttattggt tgaccttgtc atgtgcatcg attttgctag
    45181 cagaaaactt ggatgcgatg aagcatcgac aagtccaata tctgattgga tcgatgggtg
    45241 ggttatgtgt gtcggcattc ttgtcatttg tgccgtttac gcagttgcag accatttttc
    45301 tgatcacttt tctatatgga atcgcacaat ttctagttgc tagaaattat gcagttgcta
    45361 atatttttct taatccgatg gcgttgatgc tatctacact tattcgtgga gcatacttga
    45421 tttctttgat cgaatatcgt tttttaggga tcgtcatagg aagtttcatc ggtttaggtg
    45481 ttgcgtgggt aatgacggtt ggtttgcaac attatttaac ggttgttcgt caaaaattag
    45541 aatagaagga caaatatatg tgccaaaaga ggttatgaca agatttttgt cacaacctct
    45601 aattcaaggt gttcaaaagc cagattctca gcattaagtc aaattcacac aaaaatgtgg
    45661 aaaggaactt tcaaaaaaat tttatattta ttctatcaaa aaattttgtt tatgatggta
    45721 actgaataaa ctttcctgag atggtcaatg ctttccttga aagtcttaca gatattcttt
    45781 cttcatagaa agtttaagtt ttatagttag tgtacaataa aagtatgttt ataccatatg
    45841 gtgtccggat aatcagtcat ttaaacaatg aggttcaaag atatgaaaag gggaaatttg
    45901 atgaagaaaa taagcaatga aatccaaatt ctggcagaaa ctttaactct tcccaaagtc
    45961 gttatagagc aaatgattgt acaagcaaaa aacatccttg atgaggtgtt tgagcaatat
    46021 agtcatgaac taatggatcc taataaagca aaggcgactg caaagaaaat agacaaagtc
    46081 tatgaagagg aaccttttgc agcattagct atttatctat atgcagcttc tcaaagttgg
    46141 aaaaaaattt atcaaccatt gaagattcca agaactatct atttggcaac aatgaatgct
    46201 tttactagat ttattcatga acatttccaa gtaacaggaa gctatcgctt tgaccgtggt
    46261 ttttggattt ggcattacac tagtggcttg atctttcgga ttggtgaatt ggagtacgaa
    46321 atgacatatt ttccgaaagg gtacacggat ctaagattag aaggaaagca gtgcctttct
    46381 cttcatattc cttccgatgc agatttatct cagaataaga taagagatag ttacgaaagt
    46441 gccattcgtt tttttgaact ttattttcct gattaccatt accaagtgat gtacacagat
    46501 acttggttac tatcacccaa tcttactaaa tggttgaaaa aagagtcaaa aatctgtctt
    46561 tttgcagccg attatcgatt attatcagtt gatgaacagg acgatagtgg agtcccttgg
    46621 atctttggac gagtagatgc ccaaatacat gattatccag aaagtacgag tttacagcga
    46681 caagcaaaag agcaattgct tgcaggcgag cacattggct ctggcttagg tattcttact
    46741 tcataagttt agtacttcga aatagtttaa aagagcgtga gacaaaagta aagaacactt
    46801 ttgtctcacg ctctaaacac gtataaacgg cggaagcaga agcaactcct tcggaaataa
    46861 gctgaaattc acaaaaattt gaaaagcaat tttcgtgaat ttcttcttgt ttcttggagt
    46921 taaacgcttc tgtcccagcc tcttttttag tgttctatcg aacacacagt acgttcaata
    46981 ggtaaactag ctataacaat agatattaaa gttaacggac aagagggcct tttttaggta
    47041 gctaaaacgt aataatgaaa atttatttcc agagatagga gtcaatcagc tagtctgatc
    47101 gactgtttta acaagttgac tttcatttta acttttgata ccatttaaaa cacaaatcgt
    47161 aattgtttcg atttgtgttt tttagcatga ctacaatcaa agaagaaagt gggtcgtcca
    47221 tatggaaaaa acagatatct caagtgcata ccgccgcttg aaaagcccaa atatcaaaac
    47281 acgaaaacgt gcgctgaaga tcatcaaaga tgtgaaacgg aatagtggga aaaggtaaga
    47341 agaaggaaac ttaattaaaa aaatagccga aaaacgtttt tcggctattt tcaataatcg
    47401 gtttttgtgt aaggtttccg aaagaactgc tgttgatttt ccatttttaa catatgataa
    47461 attggtagaa tctttctttt caaattgata ccattcccta attccagtta tatagttaac
    47521 tacagaacca caaagcacgt acgtttataa aagtattatc tgtagttatt tttcaattcc
    47581 ctttcaacct cttattttga ccagtagtat tgatcacttt accttttaac acctttgttc
    47641 gtttttgaaa catttttagt caagaatgga aacgtaacta cataatcaaa ggttttgcga
    47701 aatatttcat gaaatatttc atgtagaagc gagcaatacg gttgcaaata accattatcg
    47761 tttaataagc agttacgaaa gctcccaata tctctaacgt tcagctcact ccatttcttt
    47821 tcttcaaaaa aatcagtgat tcgtatctct ttctatttgt cgaaaaagtt aactttaaaa
    47881 agtaacgccg aaaaaatatg caaaaaaata aaaaagcagt tactattgct agaataacat
    47941 caaggaataa taagttttgg ttttcagata atagtcgata agttgtgtat tggaatttta
    48001 gatacagtaa taaagtattt ttcatgaaat tttgtgagaa tcactattac aagtatcttt
    48061 aataaaatta atggttaagg aggaacttaa agtagaatgt aaatgaatag ttgtagtcag
    48121 tcgattgtga tactagactc aaagttgcag gaataagttt ttcaatttgt gattggaaga
    48181 taaaaaatga aaaagaaggg ctttttttta tactttgttg attgtagtgt ttattttccc
    48241 tctgtttagc caagtaacat tttctatgac tcaaccagtt tcaagtgagg aacatgataa
    48301 cctttttcgt gctacagaag agtttaagaa atatcaggaa aatattgttc cggagactcc
    48361 attagctagt gagccaatta ctgatattga tggaaaccaa ataggatggt atatacagta
    48421 cgaagttatg gtggtaaata atgactcaat agtaaaaaat acagtaggct tagagctaac
    48481 accgattgaa aaggtgagtt cattgttaac gtatatttat actgatgaaa gtgacgagac
    48541 tgagatcatt ttaacggatt actcaaaaat tgctactgat aaaaagtata tattgtggat
    48601 gtagacacta gtgaaatact ttatgatata gaaattgatg aaaatttact agatgtagca
    48661 caagaaatcg atcatcaaaa gcaggaagct attcgatatg ctggtagaaa agggaaaaga
    48721 aaatatttat tacgtgaatg tagcaaaagt tagagaagat gaaaatgagt ggaaagaatt
    48781 caagagtcgc tactcaatta actcgactcc gacatttaca gtttacagag aaggatcgat
    48841 agaaaaaact gttttttgga ctaaagaaag tggaatgtct ttagctgaag tagaagagtt
    48901 tttggattat gttagtatgc aacagtaagg gagttcttat tatgaaaaat tttgacacat
    48961 attat
//
LOCUS       DAXLPC010000009        48032 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.009, whole genome shotgun sequence.
ACCESSION   DAXLPC010000009 DAXLPC010000000
VERSION     DAXLPC010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.009"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..1008
                     /locus_tag="ACF3UE_000509"
     CDS             <1..1008
                     /locus_tag="ACF3UE_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFD3633966.1"
                     /translation="TIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDHQLITGKLM
                     NTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGWLFFFTSIF
                     IGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISILFVVIGMIISIL
                     ALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRPYRSVFLSS
                     VLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSMTNILLFVY
                     ISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLFFLTVRRLK
                     R"
     gene            1005..1772
                     /locus_tag="ACF3UE_000510"
     CDS             1005..1772
                     /locus_tag="ACF3UE_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFD3633967.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            1872..3440
                     /gene="liaX"
                     /locus_tag="ACF3UE_000511"
     CDS             1872..3440
                     /gene="liaX"
                     /locus_tag="ACF3UE_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFD3633968.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            3737..4057
                     /locus_tag="ACF3UE_000512"
     CDS             3737..4057
                     /locus_tag="ACF3UE_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFD3633969.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            4057..4407
                     /locus_tag="ACF3UE_000513"
     CDS             4057..4407
                     /locus_tag="ACF3UE_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFD3633970.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            4574..5512
                     /gene="hprK"
                     /locus_tag="ACF3UE_000514"
     CDS             4574..5512
                     /gene="hprK"
                     /locus_tag="ACF3UE_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFD3633971.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            5527..6357
                     /gene="lgt"
                     /locus_tag="ACF3UE_000515"
     CDS             5527..6357
                     /gene="lgt"
                     /locus_tag="ACF3UE_000515"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFD3633972.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            6401..7426
                     /locus_tag="ACF3UE_000516"
     CDS             6401..7426
                     /locus_tag="ACF3UE_000516"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFD3633973.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            7441..8379
                     /gene="galU"
                     /locus_tag="ACF3UE_000517"
     CDS             7441..8379
                     /gene="galU"
                     /locus_tag="ACF3UE_000517"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFD3633974.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            8504..8944
                     /locus_tag="ACF3UE_000518"
     CDS             8504..8944
                     /locus_tag="ACF3UE_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFD3633975.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            8947..9549
                     /locus_tag="ACF3UE_000519"
     CDS             8947..9549
                     /locus_tag="ACF3UE_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFD3633976.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(9608..10714)
                     /locus_tag="ACF3UE_000520"
     CDS             complement(9608..10714)
                     /locus_tag="ACF3UE_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro peptidase family protein"
                     /protein_id="HFD3633977.1"
                     /translation="MNNVKINELRQWMAQHQVELSYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            10924..11925
                     /gene="ccpA"
                     /locus_tag="ACF3UE_000521"
     CDS             10924..11925
                     /gene="ccpA"
                     /locus_tag="ACF3UE_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFD3633978.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(12262..14607)
                     /locus_tag="ACF3UE_000522"
     CDS             complement(12262..14607)
                     /locus_tag="ACF3UE_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFD3633979.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            14886..15788
                     /locus_tag="ACF3UE_000523"
     CDS             14886..15788
                     /locus_tag="ACF3UE_000523"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFD3633980.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            16001..17776
                     /locus_tag="ACF3UE_000524"
     CDS             16001..17776
                     /locus_tag="ACF3UE_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFD3633981.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(17842..19428)
                     /locus_tag="ACF3UE_000525"
     CDS             complement(17842..19428)
                     /locus_tag="ACF3UE_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFD3633982.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            19679..19903
                     /locus_tag="ACF3UE_000526"
     CDS             19679..19903
                     /locus_tag="ACF3UE_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFD3633983.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            20045..21796
                     /locus_tag="ACF3UE_000527"
     CDS             20045..21796
                     /locus_tag="ACF3UE_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFD3633984.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLMLDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            21796..23580
                     /locus_tag="ACF3UE_000528"
     CDS             21796..23580
                     /locus_tag="ACF3UE_000528"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3633985.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIITRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTSDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMMKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPIEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVEHGNHETLLAQNGLYADMYKLQSSGI"
     gene            23906..24757
                     /gene="licT"
                     /locus_tag="ACF3UE_000529"
     CDS             23906..24757
                     /gene="licT"
                     /locus_tag="ACF3UE_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFD3633986.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEDLQVHLNDSVYIALTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDKAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRCYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVIQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            24852..26738
                     /locus_tag="ACF3UE_000530"
     CDS             24852..26738
                     /locus_tag="ACF3UE_000530"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFD3633987.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVRVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTVARKFKVNEFVGMLLGAALMNPNLSLEVLSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVNYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAMPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKDEAGETDDIQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(26778..27680)
                     /locus_tag="ACF3UE_000531"
     CDS             complement(26778..27680)
                     /locus_tag="ACF3UE_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3633988.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNDVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            27911..29314
                     /locus_tag="ACF3UE_000532"
     CDS             27911..29314
                     /locus_tag="ACF3UE_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFD3633989.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLDIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETITSIYGNKETQIV
                     VSTKNDGAVPDLSADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETIGRLKEEGIEVQ
                     DELARELSSNTHIMEEV"
     gene            29314..30747
                     /locus_tag="ACF3UE_000533"
     CDS             29314..30747
                     /locus_tag="ACF3UE_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFD3633990.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEKGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWDSRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            30892..31818
                     /gene="trxB"
                     /locus_tag="ACF3UE_000534"
     CDS             30892..31818
                     /gene="trxB"
                     /locus_tag="ACF3UE_000534"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFD3633991.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            32033..33760
                     /locus_tag="ACF3UE_000535"
     CDS             32033..33760
                     /locus_tag="ACF3UE_000535"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFD3633992.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EENHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAKKVASYE
                     AIIKKMTEE"
     gene            33775..34125
                     /locus_tag="ACF3UE_000536"
     CDS             33775..34125
                     /locus_tag="ACF3UE_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFD3633993.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(34217..35077)
                     /locus_tag="ACF3UE_000537"
     CDS             complement(34217..35077)
                     /locus_tag="ACF3UE_000537"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFD3633994.1"
                     /translation="MTSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            35169..35597
                     /locus_tag="ACF3UE_000538"
     CDS             35169..35597
                     /locus_tag="ACF3UE_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFD3633995.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            35759..35935
                     /gene="rpsU"
                     /locus_tag="ACF3UE_000539"
     CDS             35759..35935
                     /gene="rpsU"
                     /locus_tag="ACF3UE_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFD3633996.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            35962..36408
                     /locus_tag="ACF3UE_000540"
     CDS             35962..36408
                     /locus_tag="ACF3UE_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFD3633997.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(36562..37941)
                     /gene="brnQ"
                     /locus_tag="ACF3UE_000541"
     CDS             complement(36562..37941)
                     /gene="brnQ"
                     /locus_tag="ACF3UE_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFD3633998.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
     gene            38647..39618
                     /locus_tag="ACF3UE_000542"
     CDS             38647..39618
                     /locus_tag="ACF3UE_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFD3633999.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            39642..41834
                     /locus_tag="ACF3UE_000543"
     CDS             39642..41834
                     /locus_tag="ACF3UE_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFD3634000.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKVNDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            41851..42327
                     /gene="ybeY"
                     /locus_tag="ACF3UE_000544"
     CDS             41851..42327
                     /gene="ybeY"
                     /locus_tag="ACF3UE_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFD3634001.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            42311..42706
                     /locus_tag="ACF3UE_000545"
     CDS             42311..42706
                     /locus_tag="ACF3UE_000545"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD3634002.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            42721..43620
                     /gene="era"
                     /locus_tag="ACF3UE_000546"
     CDS             42721..43620
                     /gene="era"
                     /locus_tag="ACF3UE_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFD3634003.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            43763..44575
                     /gene="recO"
                     /locus_tag="ACF3UE_000547"
     CDS             43763..44575
                     /gene="recO"
                     /locus_tag="ACF3UE_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFD3634004.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            44959..45876
                     /gene="glyQ"
                     /locus_tag="ACF3UE_000548"
     CDS             44959..45876
                     /gene="glyQ"
                     /locus_tag="ACF3UE_000548"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFD3634005.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            45878..47953
                     /gene="glyS"
                     /locus_tag="ACF3UE_000549"
     CDS             45878..47953
                     /gene="glyS"
                     /locus_tag="ACF3UE_000549"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFD3634006.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGKASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT        15668 a         8534 c        10148 g        13682 t
ORIGIN      
        1 actatatttt ttatttgtgt gcttacttca tgggttattc agcatcaagc cgctttatat
       61 gaagtacctg tcatcgagat agaaaaagta cgaataaaag aggatcatca attgattaca
      121 ggaaaactga tgaacacgga tcaaaaagga gaatcgattt atttatcggt tccttatcaa
      181 aaaaatcaaa tagaaacagc aaatataaaa gcgagacaaa tgtatctagt ccaaatgcat
      241 ggagatgaat ggcagctagt agcaaaaaaa aatgatggct ggcttttctt cttcacaagt
      301 atcttcattg gcgccatgtt gcttattggt ggaaaacagg gtctatttgc tttaggaagt
      361 ctcatcatca atatcgtttt acttttactt ttgttgctca tctttactaa aacagaaggg
      421 atttctctat taaatatatc tatcctgttc gtcgttatag ggatgattat tagcatattg
      481 gctttagatg gatggaatag aagcagtata atcaaaattt cagctgcagt tacgagtgtt
      541 tttttagcat tttttatttg tcttttgaca atgaatcatt ggaaagacca aggactgcgc
      601 tatgaggaac tgaattatct gacacgaccg tatcgttctg tttttctttc tagcgtactg
      661 attggaacag ctggaggaac actcgatacc gttatcacag tcattgcgac attagaagaa
      721 ttgactaagc gacaaccaga aataacagcg aaacagttat ggctttcagg aaggcaagtg
      781 ggtcgagatg tgattggctc gatgaccaat atccttttgt tcgtctatat cagtgggtca
      841 gttccatcgc ttcttttata tttaggaaat caatggtcgt tcaaagaaac gatagaacag
      901 catttatcat tggaattttt acgcgtcatt gctggcagct taggaatagt attatcgatc
      961 cctatctcgg tcctcttttt tctgactgta aggaggctga aacgatgaat gtacttatta
     1021 tacttgttgg gattttagca atcagcgtgc tacttattgg cggtacgcaa ggtatgtata
     1081 ttcttttagg cttattcatc aatttaggga tctttttcct gttgttattc ggttatcatc
     1141 agaagtggcc gatactggca ttgtcggtca taggattttt attgattgct gtggttatct
     1201 tattttttat caacggttat aatctaaaaa tgcgtgcagc ttttgtgagt atactgatct
     1261 ttttattttg tttcctacta ttgcttccta tcactgattt tttagcaatc caaggtttta
     1321 catcggtaga actagaagaa ttatctggct tagataagac tttagcgatt gattttagat
     1381 tacttacgag atcgttgctt ctgattagtc ttagtggtgc tgttttagat gcgagtgtag
     1441 caatttctag tgggacattc gaagtatatc aggcaaatcc gcaattatct ttttaccaat
     1501 tgcgccattc tagtttcgct attgctaaaa aaatattggc gtcaacagta atgacacttc
     1561 tttttgcatt catgggaagt tctttagcgt tgatcctctg gtttattgat ttagacattc
     1621 cttttcagca agtgatcaat gaaaaatcat ttgttctaga atatacgatg gctattctta
     1681 ccacattgtc cgcactactt gttcttcctt taacctgcgt gactacagca tatctcttta
     1741 caaaaaagaa agaacaactc aagatggagt aaaagttaca acttaagtcc tatgacattt
     1801 ttactgaatc agtgcataat atggatgtaa ggaaaagctt gcaaacaatt ttgcttaagg
     1861 aggcaatttc catgaaagaa agagaacgta ttttagattt agtgaaaaaa ggaatccttt
     1921 cgactgaaga aggcttagat ttattagaaa gcatggcaac tgaaaaagac gaaaagcaaa
     1981 tcaaaaaaga agcagacaag gtaactgcta gtcataaaga aaaagatcag gcaagtcaat
     2041 tgatcgataa acttgaaaac ggcgaagaag aaatttctga gccagttgat ccaaaggaaa
     2101 gagaaagaca agatcaagaa aacttagaaa agatcttaga tgaactagca actgaagcga
     2161 ataaaacttc ggcgcgtcta gatgaagtaa atgctcaatt cgctgacaat aaggcagcac
     2221 gcaatgagaa acaggaagca ttgatgcagc tgaatacaaa agaagaatta ggcgagttga
     2281 cagaagaaga attagcacag cgtcagacgt tagaagcaga aatcaaagaa ttagaagcta
     2341 gtggcgatac actgttagaa gaacaattga aattagaagc agaattaaaa gatatccgta
     2401 agaatcaatg gtctgagaaa aaagaaacgt ttactgataa gtttgaattg ccagatgatt
     2461 ggaaagatca agcaacagat acactgaatc aagtaggcga aaaaatgtca gaagctggat
     2521 cacagttagg caaattcttg aagaaaacat tccaaactgt ttcagaaaca gtgaatgaca
     2581 acatggaatg gaaagatgtc agcttacgtg tccctgggat tgcgacaacg aaatttgagc
     2641 atgaatttta ctatgaagct cctgcagcaa gtatccttga tatcaaggca gcaaacggaa
     2701 acgtgacgtt aaaaacgtgg gacagcaacg atgtgaaagt tgaagctaag atcaaacttt
     2761 acggaaaaat gggtgctgaa ccatttgaag cattctctga acggagccag attgaggtta
     2821 atgaagatca tatctccttc caaattccaa ataaacgtgt gcgtgcagac cttgttttct
     2881 acttacctaa acgagtatac gaccacgcag ctattaaact tctaaatggc aacatcatga
     2941 ttgaaacatt ggaagctaaa gatatttata caaaatctac gaatggtaac atcatcgtgg
     3001 accaattaac tgcaacgatg ctggaagtag aaggtgtaaa cggcaatatc gatattcgaa
     3061 acgggaacat cttagattct attatcgaaa cagtaaatgg tacagtgaca tttggtgcga
     3121 cagcagaaaa cctttctgtg tctttggtaa atggtgatgt acgtcttacg attaaagaag
     3181 ataatttgaa aaaagtagaa gcaagttcag tgaacggaaa tgtcaaagtc gctttaccag
     3241 atggcatcgg tttggaagga catgctaaaa caagtcttgg aagtatcaac agccgtctgt
     3301 ccaattacga agtagttcgt gagaaaaaag aacggacaaa ccaaatgttg caattccgtc
     3361 gtgtttcaga tggtgaaatc gcgcaagtgc aactttcaac gacaacagga agtatctatt
     3421 taaaagatac agataaataa agaggttgtg aaagagatgt tcagccttga gcaataagaa
     3481 gcgattttgt aaaatagctt cccctatttt acaaaattgt gccttattgc cgatagtcta
     3541 tctcttgaac accgtttacc aagagattat gaacctgcca attatcgccg agtcacaagg
     3601 aataatttca gaaaaagctc gtcacgtttt atgaatatgg taatttgtga ccgagaattt
     3661 tgcagaaaga caccgattaa gaagaaggtt gtcacaacga ttttcttcat ttaaaatagt
     3721 agaacagagg tgagacatga tgaaaaaaaa gttgacaaaa tctaataaaa atgttgtttt
     3781 gacagggact ttagcaggaa taggagaata catcgggatt gatccgactg ttatccgtgt
     3841 gctttatgta ttcctgagct tagttgcttt tggaagtcca attattttat acattttatt
     3901 agctttgatt atcccatctg cgcgttctgc acgaacaaac tatggacata acaatgcata
     3961 ttatgaaaaa aacaattatc gtgaacaaac tcgtgaacaa acaaaaaaac gcaaagaagc
     4021 ggaaaaaatc gatgatgacg aatggagtga cttttaatgt cgtactttca acgtatttta
     4081 gttaatacgt taacattcat atcattggct gttctttttc ctgcgatggt ccatgtgagc
     4141 agtatttgga cggccgttct tgccagcttc gtattgtctg tgttgaatat gtttgtcaaa
     4201 ccgattttga cgatactgtc cctgcccttt acattagtca cattgggatt gtttacgttt
     4261 gttatcaatg cagcgattct taaaatgacc tccttttttg tgggagcaga acattttagt
     4321 ttttcttcat tcggtgcagc gttgttagta gctatcttga tgtcgcttgt caatgtaatt
     4381 gtcagcgaac ataacagtag aaaataaaag aaagctgtgc cgaactatcg gcgcagtttt
     4441 tttatttaga atcaggaatg cgttttctat tacattggta attaaataaa aacgtttttt
     4501 ttaattggta gtacttttgg ctagacaatg ataaaatgat agagaacact ctaatagaaa
     4561 tgaggtagca tgaatgtcag aagttgtaaa agttagccaa ttagtgaaaa aattatcttt
     4621 ggaaatcgtg acaggcgacg agaaaagctt agaccgtgtc atcgtaactg gggacatctc
     4681 acgcccagga ctagagttga ctggttattt taattattat tcccataatc gtttacagct
     4741 atttggcagt aaagaaatca gttttgcgga acggatgatc ccagaagagc gtttgatcat
     4801 catgagaaga ttatgtagtg aagatatgcc cgcatttatt atttcaagag gattaccagc
     4861 tccagaagaa atgatccagg cagcaaatga aaatgggata gctgtactgc gttctcccat
     4921 ctcaacttct cgtttattag gagaattatc cagttattta gatggtcgcc ttgcccctcg
     4981 aacaagtgtc cacggtgttt tagtggatgt ttacggatta ggtgtactga ttcaaggtga
     5041 cagtgggata ggaaaaagtg aaacagcgtt ggagttgatc aaacgcggcc atcgattgat
     5101 cgcagacgat cgagtagatg tttatcagca agatgaatta acggtgatcg gagaaccgcc
     5161 taaaatcctg gaacatctga ttgaaatccg aggaatcggg atcattgatg taatgaatct
     5221 ttttggtgcg agtgcggtac gtggctctat gcaagtccag ttggctgttt atctggaagc
     5281 atgggcaaaa gataagaaat acgaccgtct gggctctgaa gacacgaccg ttgaaatcgc
     5341 ggaagtgggc attccacaaa taaaaatccc tgtcaaaaca ggacgaaacg ttgcaatcat
     5401 cattgaagta gccgcgatga atttccgtgc acgtacaatg ggctttgacg caacgaaaac
     5461 atttgaagaa agattaagtc gcttgattga agaaaactca ggcaacgact agcaaggagt
     5521 gacaatatgt tagcacaaat caatcgagtt gcttttgagc ttgtagggat tcctatctac
     5581 tggtatgcat tgatcatcgt atcaggtatc attatcgcta tgtggcttag cagcagagag
     5641 gctgttcggg taggattaaa agcagatgat gtgacagatt ttatgttgtg gggattgcct
     5701 atctccatta ttggcgctcg cttatattat gttttatttg atcttcccca gtatatagct
     5761 gatccaatcc aaatattcaa tatccgttca ggaggcttag ctatttatgg cggactgatt
     5821 gcaggcgcga tcacgctgta tttttttact aaatatcatt ttatttcttt gtggactttt
     5881 ttagatatcg ctgcaccaag tgtattatta gcacaggcaa tcggtcgttg gggaaatttc
     5941 atgaaccacg aagcatatgg accagacacg acgcgaagct tcttagaaag tctgcattta
     6001 ccgcaattca tcattgataa tatgtatatc gaagggatct atcgtcaacc aacatttctt
     6061 tatgaatcac tttggagttt gattggattt attttgcttt tgtttttacg aaagaaacca
     6121 caccttttga aaaaaggcga agtcctttta tgttatctaa tgtggtatag tttcgggcgt
     6181 ttctttattg aaggattacg tacagacagt ctttactttt taggtgtgat ccgtatttct
     6241 caattattat ctgctgtgtt atttgtcggt acattgattc tatttatttg gcgcagaaaa
     6301 aaaggaaatt taccggatta tgaccgctca ttaggaaaaa atcaacaaat tatctgattt
     6361 ttagagcgtt aaaaatgaaa aaaatttcag gagtggtaaa atgaattata gagtagcggt
     6421 tttaggacca ggctcttggg gtactgcttt ggcacaagtc ctcgccgaaa acggacatga
     6481 cgttcggatt tggggacatc gtgcttcaca agtagaagaa atcaacaccc aacacacgaa
     6541 tcaacgttat ttaccagatc attatctacc cgattccatc caagcattca ccaatatgga
     6601 agatgcagta aaagacgcag atgcggtgct attcgtcatt ccaacgaaag caatacgttc
     6661 tgttgcaaaa gaactagtgc ctaaattgaa tacaaagcca gtgatcatcc atgcaagtaa
     6721 aggattagaa cagggaacac ataaaaggat ctctgacatc ttgttagagg aaatcccagc
     6781 agaaaaaaga aaagctgttg ttgttctttc tggaccaagc catgcagaag aagtagcaaa
     6841 acatgacatc actacgatca cagctgcaag tacagatgca aaagcagcaa aatatgtaca
     6901 agagctgttc atgaataatt attttcggat ctataccaat cctgatgtga tcggtgtaga
     6961 gatgggggca gctttgaaaa atattattgc tattggtgct ggcgctattc acggcttagg
     7021 gtttggcgat aatgcaaagg cagcaatcat gacgcgcgga ttagctgaga tcagccgttt
     7081 aggtgtagca atgggtgcca acccgctgac ctttatcgga ttaagcggaa taggcgatct
     7141 agtcgttact tgcacaagtg ttcattctag gaactggcgc gcaggcaact tgttaggaca
     7201 agggcagccc ctagaagagg tgctagccaa tatgggaatg gtcgttgaag gtgtgaatac
     7261 tacccaagca gcgatggaac tagcccaaat gatggaaatc gaaatgccca tcactcaaac
     7321 aatctatgaa gtgctgtatg aacaaaaaga aatcaaaaca gccgcaaaag aaatcatgtt
     7381 acgtgatgga aaaaaagaaa atgaattctc attaacaatt ttttgaagga gcgaatgtat
     7441 atgaaagtta aaaaagcagt tattccagca gcaggattag gaacaagatt tttaccagca
     7501 acaaaagcta tggcaaagga aatgttgcca attgttgata aaccaacaat ccagttcatc
     7561 gttgaagaag cgttgaaatc aggtatcgaa gacatcttga tcgttacagg aaaagctaaa
     7621 cgaccaatcg aagatcactt tgattcaaat attgaattag aaacaaacct aagtgaaaaa
     7681 ggaaagaccg aattattgaa attagtagaa gaaacgacag atgtcaactt gcatttcatc
     7741 cgtcaatctc atccaaaggg tttaggacat gccgttcttc aagcaagagc ctttattgga
     7801 aatgaaccat ttgtcgttat gctaggcgat gatataatgg aagacgaagt accattgaca
     7861 cagcaattaa tcgatgatta cgaacgtact catgcttcta cgatcgccgt tatgcaagtt
     7921 cctcatgatg aaacttcaaa atacggaatt atcaatccag gagaagtatt ggaagatggg
     7981 ttatacaatg tcaaaaactt tgttgaaaaa ccagatccaa gcaaagcacc aagtgattta
     8041 gctattattg gacgttactt attgactcca gaaatttttg atgtattgtc cgagcaacaa
     8101 ccaggagccg gaaatgaaat ccaactaact gacgcaatcg atacattgaa taaaacacaa
     8161 cgcgtatttg cccgtaaatt cacaggtaaa cgttacgatg tcggtgacaa atttggtttt
     8221 atgaaaacaa gtattgaata tggtctaaca catccagaag taggtgcacc tttacgtgag
     8281 tacatcctgt ctttaggtaa aacattagaa gcagaaggaa gcaagatcga tcataatcca
     8341 aaaggaataa cagaaatcaa agaagaaaag aaaaaataac ccttttttct aacgagcttc
     8401 agctgctaat tgaataaaaa gtagttgaag ctcgttttta tttgtttaaa aaacacgaaa
     8461 atgctatcct tatagaaaag agagacaaga agggagtttg atcatgtcag gaggagaaat
     8521 tgcaggattg atcgcagcaa tcgcctttgc gatacttgtc gtttttatcg ttcgtgtgtt
     8581 gttgcaagtt tctaaaactt tagaaaaagt agatcagact gtagcagaag caaatacgac
     8641 gatcgaaatc gtcacaaaag acgtagatct tttgtctaga caagtagaag gcttactggt
     8701 caaaagtaat gaactgctct tggatatcaa tggaaaagtc gcaacgatcg atccattgtt
     8761 cacagcagtt gctgatttaa gtgaaagtgt atcagaactt aatcattcta gtaaaaacat
     8821 cgcgacgaaa gtcggcggaa tcggtaaaac gacagctaaa gcgacggttg ccggaaaagt
     8881 cggtgggaca gcgatgaaat tttttaaaaa caaaaaacat actgaaacga caggaggaaa
     8941 ataaaaatgg ctaaaaaagg tggattttta ttaggtgcag tagtcggagg cacagccgca
     9001 gcaatcgccg cgttattgtt agcaccaaaa tctggtaaag aacttcggga tgaattagct
     9061 gcccaagcgg atgatttgat ggatatggct tcagattaca cagatatggc gaaagaaaaa
     9121 tcgactgagt taacaggtat tgcaaaagaa aaagcgcaag atctttctca acaagcaggt
     9181 gatctagcag gtagtgtcaa acaaaaagta agtgaatcag cagatgaagc aggaagtgaa
     9241 tctgacgata tcttgttaaa tcttaaagaa caatcagctg acttatctaa tcgtttcaaa
     9301 aaaacggcag aagatatgaa aaaacctgca gatgaattag gaagtattgc taaagatact
     9361 tcagaagata tcatgattga tgtaaaagac gctgctggta aagcaggaga tactgtcaat
     9421 gaaggaatgt cagaagcaaa accagttgca gatgactcaa aagaaatgat gaaaatggca
     9481 aaagaagatg cgaaagaagc taaaaaagaa ataaaagata caatgacaga ttcatctaca
     9541 aatcactaaa atcacaaatt tatagaataa aaaggtggga gcggactagc tctcaccttt
     9601 tttactctta tttttctaaa acaagtaatt cttttggtgt agtcgtgaat ggcacacagc
     9661 catcgcttgt cacatataca cagtcttcga tacgtacccc tactttttca ggaatataga
     9721 ttcctggttc aagagagaag cacatccctt cttcgattac taagtcattt ccttctacaa
     9781 gggaagggaa ttcgtggacg gttgttccga tcccgtgacc taaacggtga ttgaaatatt
     9841 cgccgtagcc atagctgttg atcacgtttc gtgcgatttg atcaagttca cctgctgtca
     9901 cacctggacg gacggcttct tgtgcggcaa gctgtgcttc aagagtgatg ttgtagattt
     9961 tttcttggaa gtcggttggt ttttgataag caattgtacg agtagcatca ctgcaatagc
    10021 cattccaaac aacgccaaga tcgaataaca caagttcatt cggtgaaatc ttcgtatttc
    10081 ctggtgtacc atgagggctt gcagcatttg ctcctgcaag gactaatgtg tcgaaagaca
    10141 tttgtgaaac accttgtttt ttcaattggt attcaatttc tgcaatgatc gcttgttcag
    10201 tcacgccttc tttcactgct ttaaagccaa tctcaaatgc aacatcggcc catttaccag
    10261 cttcgatcag tttgtctttt tcctctagag ttttgatcag ttgtagacgt tggatgatgg
    10321 aagttagatc agtgtaagaa tccgttcccg tcaagatatc agagatagca tcgaagcgct
    10381 cgacagtcaa ggcgttcttt tcaatcccta cattgccagg ctgaccatag cgagcacgaa
    10441 gttcttttcc gatgatctcc caagggtttt cgctgtctaa atagccacgg acatcatacg
    10501 cccaactact gttttgagca tcttcaactt ccaaagcagg agtgaaaagg aaaggatctt
    10561 gttcaagagg gataaaaaga gctagtacac gctcatgagg atcactttcg tatccggaaa
    10621 agtaagcgat gtggccaggg tcgctgatat aagacaattc gacttggtgt tgtgccatcc
    10681 attgacgtag ttcattgatt tttacgttat tcatttggca acctactttc taaattaatt
    10741 ttgtattcaa taattgtacc actgatttat taaaagacca acgttctaaa aactgaaaaa
    10801 agtaaaaatt ttcatgaaaa cagagataaa acggttgcaa ttcttgagat tatttgatat
    10861 tctattttag aaatgtaaga cgtattttca gaaaacatat aaaatatgaa taggagaaca
    10921 caaatggaaa agcaaacaat cactatctat gatgtagcga gagaggcaaa tgtttcgatg
    10981 gctactgttt cacgtgtcgt aaatggcaat ccaaacgtta aaccagcaac aagaaaaaaa
    11041 gtcttggaag ttatcgatcg cttggattat cgtccaaacg cagttgcgcg tggcttggca
    11101 agtaagaaaa caacaacagt tggtgtaatc atccctgatg tcagcaatat gttctttgct
    11161 tctttagcac gtggtatcga tgatgtggca acaatgtaca aatacaatat tatcttagca
    11221 aattcagatg gcaacgacca aaaagaagtc aatgtattga ataacttact ggctaagcaa
    11281 gtggacggcg tgatcttcat gggtcaccat atcacagacg aaatccgtgg agaattttca
    11341 cgttcaaaaa ctcctgttgt attagctggc tctattgatc cagatgaaca agtaggtagc
    11401 gtaaacattg attatgtatc cgcaacaaaa gatgcagtaa acaaattggc aaaaagcggc
    11461 aataaaaaaa tcgcttttgt cagtggtgcg ttgatcgatc ccatcaatgg acaaaatcgt
    11521 ctgaaaggct ataaagaagc attaagcgaa aataacctac catatagcga aggattgatc
    11581 tttgaagcac aatacaactt caaagatggt ctatctctag tcgatcggat ccataatagc
    11641 ggtgcaacag ctgtctatgt ttcagatgat gaattagcca tcggtatttt ggatggttta
    11701 ttagaccgtg gcgtgaaagt accggaagaa ttcgaaatca tcacaagtaa caattcacta
    11761 ctgacagaag tagctcgtcc tcgtttaaca agtatcacac aaccattata cgatttaggg
    11821 gcggtatcta tgcgcctatt gacgaaaatg atgaataaag aagaagtcga agaaaaaacg
    11881 attatcttgc cttatggaat cgaagaaaaa ggatctacaa aataataaaa ggacaaccat
    11941 tcagaggttg tgtgcctgcc gtttaactct gcgttacaag gagcaatttc aaaaaacagc
    12001 atctcatgtt tgatgaatat tgtgactcgt gattcggagt tggcaggaga acaccgttta
    12061 tttgggaaaa ggggttatga caaaattttg ttataatcct ttttttgtgt cttaaaaaag
    12121 agagaaagtg gttgaaatta catttatcgt atataaaaca atccgtgtat agatgctgca
    12181 ttttgttcac caccatcaaa aaaataaggg actgtgacaa tactattgtc acaatccctt
    12241 attactgtgt attctattaa atcaatcatc tttctcatct gattctttag ttgcttgatt
    12301 cgctcttgca taagctgaag cggtgttcca gtaatctgta tagttttcat cggtaccgcc
    12361 aacgccaaat ttaaaggcgc ttttcttcgg tccatttttc gcccatagcg attcaactgt
    12421 ttttcctggt gtttggatgg attttttatt gacagtaact tttccaggtg tttgaccagt
    12481 aaatccagat acttttttct tcatcacatc agatgataat tcgaatttct catcagtgcc
    12541 aaaaatgtca ggttttgctt ggtaagcttg attgatcaga ttggcaagat aattagccga
    12601 acgtatcctt gctttgctgt ccattccagt attgtcatcg tgccctgccc agctactgat
    12661 ggtaatagac ggagtagaga caattagcca tgaatctcgg tattcattgg tagaaccagt
    12721 ttttccgacc caatctgctt ttcctagatt tccgtttaag cttgagatgg catctttgaa
    12781 tggtgtagtg atttttgcat tgatcacact acgcatcatg tcattcatga tcgatgccgt
    12841 tgcttccgaa tagatccgga cagagttgct ttcgtgttta taaattacat ttcctgcgtt
    12901 atctgtgatg gaatcgatga tatagccttc ttcatagacg ccgccgtttg ctaaagcctg
    12961 aaatccgttg gtctgttgaa gcgtcgtgac atctactgta cctaaaggag cagattcaac
    13021 gccccaattg tcatttgccg ggtagttcat ctttgccaag tagtgctcgt aagcatattg
    13081 tttcgatcca ccggaattca acacatcttg atataagtga taagccggga tattgttgga
    13141 ccattctagt gactcacgga cggtttggaa ggtgttcgat ccttcgttag tagcattgac
    13201 gattttctcg ccagcatttt ctccttcttg ccaagttgtt gcataatctg atacacggga
    13261 ttctgatccg ataagcccca tgtcgattgc aggtccataa acaagaactg gtttgattga
    13321 tgagccagct tgacgttctg tatcgaaggc atggttattt tgattctgac tgtaattccg
    13381 tccgccaacg aatccgtaga tgcggccagt tctgttatcc atcaatacat ttccggtttc
    13441 tacttgactg ccagcaccat catctaacat gtatccataa ttttcaacgc cattttgcaa
    13501 tgcagcatag acatctttat cgattgtcga atggattgta tatcctttat tttggatcgt
    13561 ttgctgtgcc ttttgataat aagcgtcact gaccgatgaa tcagacatat cagcgttgtc
    13621 tttttcagcc aattgttgtg caatgattct tgttgcttca ttcatcacag tataatacaa
    13681 gaattctctg tcagtctgtt ctgcgatttg ttgtggtaga aagtcttttg taaggtcata
    13741 ggcttttgct tcttcgtatt gttctttcgt aatttggcct tcacgataca tactgaataa
    13801 aacaaaatct tttctggcaa ggccggcaga aagatcttct tttagcgcgc ctgtgttcgt
    13861 gtatggacta tacgtgatcg ggctttgggg taatccagcg atataagcag cttgcggcag
    13921 cgtcacatct tttgcatcta caccaaagat tccttttgca gcttcctgga ctccagcaat
    13981 gttttgtccc ttattattac gaccaaatgg tgagacattc aaatacgtag caatgatctc
    14041 atcttttgaa aagtattttt ctacttgtgc agaaagaatg atctcgtttg ctttacgttt
    14101 gaatgttgtt tcatctgtaa ggatctgctg tttgactaat tgctgtgtca aagttgatcc
    14161 accagaagag ccaataccag tagcttcaga tactaatgct cgtaaaacag ctttaggaac
    14221 gtaaccttgg tgtttatcga agtattcatc ctctgtgctg ataattgcag ttttcaataa
    14281 aggtgaaatc ttatcagatg aaatagtcgt gcgcatcaga tctgtctgga tttttgatat
    14341 ctctgtatta tctgcataaa caatctttga cgtttctgta atgtttccta gttctgtctg
    14401 cagtgctttt ttagtcggca attgtgtgtc ttcgacgaga taggcaaaat agccagcgcc
    14461 tattccaata cctagagctg cgaacatcaa aagaagaaca gtaataaaaa cagtcaatga
    14521 ttgaaaaact ctaaaaataa tcttaggaac aaaccatttt tctttttttc ttctattctg
    14581 tttttttcga gtatttttgc gtggcaaaag ggtcacctca actaatggtt ttatttcgct
    14641 aattatagca aataatagaa caaaaaaaca gacaaggctg tttttggcag gaatttcttt
    14701 tttaaaagag ttaaaacgtg agaaaatgat ctttattata aaagagttct taagcttttc
    14761 tttagagaaa atttcagtta ctatggagaa cagggcaaag aaaaatcaat cattttcttt
    14821 gtatatcatc ttaccaatat ataggaattg ttagtaacaa ttgcctttca aggaggaatc
    14881 catccatgtt attaggctca cacgtcagca tgagcggaaa gaaaatgctg ttaggagcag
    14941 cagaagaagc agccagttat ggatcttcga cttttatgat ctatacaggc gcccctcaaa
    15001 acactagaag aaaagccatc gaagagatga atattgatgc cggaaaagcg tacatggcag
    15061 aaaaaggtct aacaaatatc gtcgttcatg ccccttatat cattaatttg gggaatacga
    15121 tcaaaccaga aatgtttcct tttgccgtcc aatttctgag agaagagatt gttcgtgcgg
    15181 aagctttagg cgctactcaa attacacttc acccaggtgc tcatgtaggg gcaggaacag
    15241 aagccggaat tgctagaatt attgaaggct tgaatgaagt tttgacaaaa gaacagacgg
    15301 cacaaatcgc tttggagaca atggcaggta aaggtacgga aatcggtcga acatttgagg
    15361 aattagcgca aatcatcgat ggagtaaaat tgaatgaaaa attatccgtt acttttgaca
    15421 cctgtcatac gaatgatgcc ggttataata ttaaagaaga cttttcaggt gtaatggaag
    15481 agtttgataa gatcatcggg ttagatcggc ttaaagtact ccatatcaat gattctaaaa
    15541 atccgcaagg ttcgcataaa gaccggcacg ccaatattgg ttttggaaca atcggattcg
    15601 acacgctgaa taagatcgtc catgatccaa tgtttgacaa tatttcgaaa atcttggaaa
    15661 ctccctatgt aggcaaagat aaaaagaaag cttacgcacc atatggaaaa gaaatcgcca
    15721 tgttcaaagc gcaaacattc gatccagaag tgtttcctga gttattagca gaagaagtga
    15781 tactctaaga ttttctatct gacagcagca aaaaaggacc aggcacattg ccttgtcctt
    15841 ttttgtttaa gaaacaaagg agtacttttt gcagtctttt tcatcatgca tcttctcccc
    15901 cctcttttta aatttagaca aacaaggtat actggtagaa aagtaaaaaa acgaaaagtt
    15961 tcacaagcaa gtggcaaaac gtgattggaa ggacgaaaag atgctgaaca ctttaaaacc
    16021 cttgatcaac caactaaaaa agaaacatac atactttatt cttggcatag ccctattatt
    16081 tacaattatt cgtttgtatt tatatagtaa agcaatctat ggaacagaca tgtcggcaac
    16141 ctatgatgac cagctgctga ttcgctatgc tcaaaatatt ttggacggta aatggctagg
    16201 ggagtatacg actacaacac tttccaaagg aatctcctac agcttatttt tagtacttgc
    16261 acataaactg catctttctt atgcagtttt gttcggcatg ttcagtattt ttgccagtat
    16321 attggttgca ctcgcgttta aaccgattgt gaagaacaag tatcttcttt taagtatcta
    16381 tttttatttt ttgttttctc cgattagttt tacacatgaa tattccactc gaacatatcg
    16441 taatgccctc gtgattccgg ctgttgagat cattatcgct tgtttattag ctatttatta
    16501 ccgcaaatac ggttctagca gaaaattgct gccatggttt ttagggcttt ctgtcgcttt
    16561 tcctttcttt tggttcattc gcgaagattc tatctggctt cttcctttta ctgtagtagc
    16621 tttgggtatc agtttcgtcc agatcttgct agggcaagac ttttctttca aagaagtaaa
    16681 gaagttaaaa aaacgactct ttcttctctc gaaacgggaa tggctgaaac tttcattgtt
    16741 tttacttcct atagttggct tttccatcgt ctatcaatgg atcgaatata aaaatgagac
    16801 aacatacggt attgcaacca tcaatgaccg ttccagtgga gaatttggac gtttgatgaa
    16861 acaactgatc cgaatagatg atgaaacgaa cttgaataaa gaaaacagtg agatatgggt
    16921 ctcacatgct gcactaaata aagcattagc cgcatctcct acattccata ctgtttctac
    16981 ccgtattgac gaattatata cgactcacgc gtggactcaa ggtggaaaag taaaagaatt
    17041 acccggagat atcatctttt gggcattgcg agatgtggta agcgaatctg gttattacca
    17101 aaacaatgca aaagaaacca atgatttttg gaaaaaagtc aaccaagaat tagaagaagc
    17161 ctatcacaag ggaacaatca aaaagaaaaa agagttctat ctgatgggat caggagatgg
    17221 aaagacgatg agtgatctgc caatcgtatt cgatttcctt caatcaggat acgcttatgc
    17281 atggcgatat aaagatttcc atcaaggagg aaattatagt ttcggaacgc aagaacaagt
    17341 caaacaggct caagaattat taaaccttcc gctaatggag aattggatcg atagtaatga
    17401 accgagaaca cctaatttcc aattaacaaa atcagcaaaa gtcgcgaatg tcatcataaa
    17461 aatttaccaa gttctggcta ttcccgtgct gattgcttca atagcaggga tattacttat
    17521 gatactagga accgtatttg caaaagctga tcgtgcctat tatagttcct ctttgattgt
    17581 ggtcaccgga ttaatactga cacaattggt ttttcttttc ggtgtctcat ggttttgttc
    17641 ttatgcgcca gaaaaaaagg actatttttt aagtgtctac actggtgcag gcgtgccatt
    17701 aacgcaattc atcgtagtaa caagcatgct agttttcagt aaattaaatc tgaaaaaagc
    17761 tttatcttct aaataaaaag acccttggta gctagatttt taacctaact atcaagggtc
    17821 tttgtgtgga aaaatcagtt tttattcgat ttcttctacc gtttcctgca aaagctgttc
    17881 atattttttg tttcctttat ataaatcacc aatcgtccat gccaacagga gaaggacaag
    17941 aacaatgatt acataagcga tgtgatcagc caatgctagt tgagcggaag tggcttgctc
    18001 gccgaagaaa ctttcgatct gtcctggtaa tcctcgtaag ttcaagtaag ttagactaat
    18061 cacagagaac cagccaagaa gttttacgat gaatgaattt ttaaatcggc tacccatctc
    18121 cgcttggctg ttggtcatca tcagtaaagg aatcatcgaa aacggcaacg caaaagccaa
    18181 gaacacctgg gattcattca ttaagttatt caaagcggca tgttcttcga tcgttccttt
    18241 tgtacttgta aacaaaacac aaatcaatac aggaatcaca gaaagcaatc gtgtgaccag
    18301 tcttcttagc caaatcggga tacgcatatg gatgaatcct tccatgatga cttgaccggt
    18361 caacgtacca gtaatagtag agttctggcc agaagcaaga agtgctacag caaataaagt
    18421 ggacaagata ccagattttg ctacagcaat caaaatacca ttgctcatag ctgatggatc
    18481 agataaagct tcatacagac caaaaaagga aggatcttgg acagaaccgg ttttgaagac
    18541 agcgacaccc atgatcaata gcagtgcatt gactagaaaa gccattgaca actggatatt
    18601 agaatcccaa gtagaaaaac gtacagcttg tgctacatct tcttcgtttt ggtgatcgat
    18661 cttccgagtt tgtgaaactg ctgaatgaag atataagtta tgcggcatga ctgttgcacc
    18721 aataatccct aaagctccag tcagcggagt ttcgccgccg atgaccggtg agtctgagaa
    18781 tgtatgactg ttagggataa agccagcaaa taaactgtgc caatctgggt tagacaagcc
    18841 aacttgatag acaaaaacga ataaaatgac gaaaattaag cagacaacca gtgcttcgat
    18901 cttacgaaac ccgacttttg tcagtagtaa gagaacgaaa acatctaata cagtaataaa
    18961 gacggcaatc accaatggaa tatcaaaaag taagtagagg gcgattgctg caccaatgac
    19021 ttctgcaata tctgttgcca taatggctaa ttcagtcaag atccataaaa tgacacctaa
    19081 tgtcttactt gtgcgtgctc ggattgcctg tgccaaatcc atttggctca cgattcctaa
    19141 ttttgctgcc atatactgta aaagcatagc aatcagacta gacatcaaaa taactgacat
    19201 caataaatat tggaaatttt gtcctccggt gatcgaagta gaccagttac ccgggtccat
    19261 atacccaact gctactaacg caccaggtcc agagtaagca agaagtgttt taaaaaaact
    19321 tttccccttt ggtacatcaa ctgttccatt tacttcagct aaagataaac catttgtatg
    19381 ttcaataagt cgatgcttat gaaattgttt attggattga ttattcaaga aaaaaccacc
    19441 tttcctattt atctacgatt acattctaca cctcaaaaag aaaaaattaa agaaaaagat
    19501 tcggtacgcc taattttttt tcatggcgcg tcttgctaga tgacgaaaga aattttgttc
    19561 tcctctaaaa aaaccactat tttttgcatg aaactaaaga atacgccttt cttttttcaa
    19621 taaactttag taaaataagt cattgagagc aattcggaaa tagaaaggag agatttatat
    19681 gttatcaaca ggtattgtcg tacttattgc tattattgct ttgctaatcg gcgcagtagg
    19741 tggctttttc ctagcgcgta aatatatgaa agactattta gaaaaaaatc ctcccgttaa
    19801 tgaggacatg ttgcgatcaa tgatgatgtc aatggggcaa aaaccatctg agaagaaaat
    19861 tcgccagatg atgcagcaaa tgaagaacca agggaaaaaa taggttctga cccaacgact
    19921 ttttacgggc tgattttttc agtccgtttt ttatttcgta atttgttaga ctattcagat
    19981 tattcagcaa aaaagacaag cacagacaat cctaggctct tgataaagac aaaggaggag
    20041 taaaatgtcg atttttagaa aattaggctg gttttttcgt caggaaaaga aacattattt
    20101 aattggggtt ttctcgctat tcgcagtggc cttggtacag ttagttcctc caaaagtgat
    20161 tgggatcatc attgatgaga tcgccgataa aaatttatca ataaagatca ttttcgggtg
    20221 gatcttccta ttgattatcg ctgctttttt acaatatctt tttcgttata tctggcggac
    20281 gaatatttgg ggaagtgcag ctcgattgga gaaagaactt cggcagcagt tattcaaaca
    20341 ttttacagaa atggacaatc tcttttacca aaaatatcgg actggggatt tgatggctca
    20401 cgcaacgaat gatttgaatg cgatccagaa tgtagcagga gctggtatct tgacctttgc
    20461 agattcagtg attacgggcg gaacaacgat cattgcgatg attttgttta ttgattggcg
    20521 cttaacactg attgcgctga ttcctctgcc tttgctggcc gtcacttcac gagtgctggg
    20581 gtcaaaactc catgatgctt ttcgtgattc gcaagaagct ttttctagta tcaatgataa
    20641 gacacaagaa agtatcactg ggatcaaagt cattaaaaca tttggacaag aaaaagaaga
    20701 tctagcggat tttgaagaaa agattgaaga tgcaattatt aaaaacaaac gagtcaattt
    20761 tttagactcc ttatttgatc cattcattac cttgattatc ggtctgtctt atgttgcaac
    20821 aattatttta ggtggaaagt atgtcttgga aggcacgatc tcgatcgggc agatggtctc
    20881 atttattagt tatatcggta tgcttgtttg gccgatgttt gcgattggtc gattgttcaa
    20941 cgtattggaa agaggaaatg cttcttatga tcgcgtcaat gaacttttgc atgaaaagac
    21001 gcatatcgtg gaacaactgg gtgcagtgca gaccccggca aaaggcgagc tgaatgtagc
    21061 tatttcctct tttaattatc cgaaagaaga atcaccagca ttagaacaaa tcaagtttgc
    21121 gatccaagaa ggagaaacat taggtattgt tgggaaaact ggtgcgggaa aaacgacgat
    21181 catcaaatta ctgatgcgtg aatacgatga ttatcaaggg aaaatccaat ttggcggacg
    21241 ttcgatcaaa gaatattcat tgaatgcttt attaggatca atcggctatg tgcctcagga
    21301 ccacttcttg ttttcgatga ccattcgaga taatatccgt ttttctaatc caaaactttc
    21361 agaagaagaa gtagagcatg cggcttcttt agcatttatc aacaatgaaa tcaaggaatt
    21421 accaaaaggt tatgatacct tagttggaga acgtggagtc tctttatctg gcggacagaa
    21481 acaaaggatt tcgattgctc gagcattgat caaaaatcct gaattattaa tgttagatga
    21541 tgcactttct gcagtagatg ccaaaacaga agaagctatc ttgcataatt taaaagaaat
    21601 aagaaaagag aaaacaacta tcattgcagc tcaccgttta agtagcgtaa tgcatgcaaa
    21661 agaaatcatt gttgtcgatc aagggaaaat cattgaacga ggaacccatc atgagctgct
    21721 tgcactaggc ggctggtatg aacaaatgtg ggagaaacag caattagaag cgaagataga
    21781 aggaggcgag gcctgatgga tgaaaattat caatcggaat ggacaaaatc gattccactt
    21841 aaagaacaga aaaagatcat cacacgactg atgaagttcg ccaaaccttt tagaagaacg
    21901 ttcatcgttg ctatcttatt tgcgtttgct ctgtctgtga tcaatgtcct attgccaagg
    21961 atcatccaaa cttttatgga tgatcatctg gctaaacagt cggctacgac acaagttatt
    22021 ttgttttttg ctggtatgta cttatttgga gtcatagtaa aaagtatcat ttggtttttc
    22081 caatggtatt tgtattccat ggcttcattg aagacctatc agtatattag ggtaaaatta
    22141 tttgaaaagc tgcatacact aggtatgcgt tattttgatc agacaccggc aggttcaacc
    22201 gtttctcgag tgacgagtga cacagaaacg ctatttgaat tttggtacgt ctttttgatg
    22261 gtattgactg ggatctttgc agtcgtttct tcattcattg ccatgtttca aatcaatgga
    22321 gaaattgcct tgtggacttt ggtgttcttg ccaattttag gaatcgtcat ctggtattac
    22381 cagaaattta gttctcgtat ttaccggaat atgcgagaaa aattaagtca gctgaatacg
    22441 aaattgaatg aatcgatttc cggcatgcgt attatccagc agtttcgcca agaagctcgt
    22501 ttagctaaag aatttgaaca agtgaacaat gagtatttag acacgcgtta tgcgatgatg
    22561 aaaacgaatt cgattctatt aagtccgatc atcaattttc tatatgcact ggcgattgcg
    22621 ttggtgttga ctttgtttgg gatcgatgcg ttgcattctc ccatagaagt tggactgatc
    22681 tatgcattta cgacctatgt ccagggattt tttaatccaa tgtctcaaat gatggacttt
    22741 ttgagcatct tcacagatgg gatggttgct ggtagtcgta tcttgaagat tatggataca
    22801 gaagaatatg caccacaaca aaaccctgga gcagatcaaa tgattacttc aggtaagatt
    22861 gagtttcgca atgtaagctt ttcttatgat ggagagcaca atgtattaaa caatatctct
    22921 tttgttgcta atccgggaga gaccgttgca ttagtgggac acaccggaag tgggaaaagc
    22981 tcgatcatca atgtgttgat gcggttttac gaattttatg aaggtcagat attgattgat
    23041 gatcatgaca ttcgagaata tccaatggaa gagttacgta agaaaatggg gctggtcttg
    23101 caagatgctt tcttgtttta tggggatatc gcaggaaata ttcggatgat gaatccagct
    23161 atcacagacg aacagatacg ccatgcggct gagtttgttc aagcaaacaa attcatcgat
    23221 gaattaccaa aaggatatca ctcaaaagtg atcgaacatg gtgccagcta ttctagtgga
    23281 caacgacagc tgatcacttt tgcgcgaaca atcgtgactg atcctaaaat tctagtattg
    23341 gatgaagcaa cagcaaatat cgatactgaa acagaaggat tgatccaaga aggattggcg
    23401 aaaatgcgac aaggacggac aacgattgcg attgcccatc ggctgtcaac gattcgagat
    23461 gcagaattga ttttagtttt agacaaaggt catatagtag aacacgggaa tcatgaaaca
    23521 cttctagcgc aaaatggttt gtatgcagat atgtacaaac tgcaaagcag tggtatataa
    23581 aagatgttgt gacagtagca ttttgaccta agcactagag tgaaaataaa acatagcttc
    23641 ccatattttt catctgtgag agttagtgtc gtagttacca gatttaaaaa agacgacgcc
    23701 agctagtcag aagtgcctag tagcccctaa gaaagcgttg acaaaatcgt ttgctttcga
    23761 taatacaaag aaaacgatac aacttggata gtgattgcct aatgcaagct aaacctgatg
    23821 agtctcccat ggtttcatgg acggcttttt gggtttttct ttttgttttg gatacagccc
    23881 tatatatcat ggaaaggagc aaaacatgct gattgagaaa gtactgaata acaacgtcgt
    23941 aataaccagg gatgaaagaa atcaggaaat gatcgtgatg ggaaaaggtt tggcattcaa
    24001 aaagaaagtg ggtgacccga tttttgactc atgcatcgac aaaaaatttc agttgacaaa
    24061 tgacggactt tcacaacagt tccaagaatt ggcacaagcg attcctcttg agtacttaga
    24121 aatttcttgt gaaatcattg aatatacaaa agaggatcta caagtccatt tgaatgattc
    24181 tgtgtatatt gcattgacgg atcatttgta tacagctatc gaacgtcaaa aaatggggat
    24241 ctttgtgcca aatgtattgc tgtatgatat caaacaactg tttcctaaag agtatgccat
    24301 tgggaaaaaa acagtgaaga aaatctcgga taaataccac atcaagttat cagaagacaa
    24361 agccggattt atcgcattgc atttagttaa tgcacaaggc attcaaagcc agcaagacaa
    24421 tacctacctg tttaccacaa caatacagga tattttaaat atcgtccgct gttactataa
    24481 gattactttt gatgaagatt cagtccattt ttttcgattt gtcacacacc tacgtttttt
    24541 tctgacacgt gttctagatg gagcgaaatc agaagatgga gaagtttctg aggaattgtt
    24601 ccaagttatt caaaaaaaat ataaggatac gtttggttgc gttgagaaaa tagcagactt
    24661 tttaaccggg gctttcgact accagatgtc cacggatgaa aaaatgtatt taacgatcca
    24721 tactgcgcgt ttagtgcatg agaatcgttg taaataaata aaaaggagga caaattaaca
    24781 cgaacgtatg aaataagggt agtgacattc agttggctaa accttccact aattaattgg
    24841 agggaacaga aatgggaaaa taccaagaat tagcgagcaa aattgtagaa aatgtcggcg
    24901 ggaaggaaaa tatcaatggt ttgacacatt gtatcacaag gcttcgtttc aaattaaaaa
    24961 acgaagaaaa agcaaatgat gagatcttga aaaatatgga cggtattgtg acggtaatgc
    25021 gagcgggagg acagtaccaa gttgtcatcg ggaatcatgt gcgagtcgtg tttgaagagg
    25081 ttataaaagc aggaaacctt acttttgatg aggctgtttc aacagaaaaa atgagaccgt
    25141 ttgatatgct tattgatgga atatcgggat gtttccagcc attccttgct atcctggctg
    25201 ctggtgggat gattcgtgga ctgacagcat tacttgtctt cttaggcgcg tttgatcgcg
    25261 gttctggaac atttgttatg ttcgacaata tcggtgattc tgtattccaa tttatgcctg
    25321 ttattatcgg tttaacagtt gcccgtaaat ttaaagtaaa tgaattcgta gggatgttgc
    25381 ttggcgcagc attaatgaat cctaacttgt cgctggaagt tttgagtggt gcagcagaag
    25441 caccactgac gaccatattt tctggtacta tttttgaagc acctatttat caaacagtat
    25501 ttggcattcc ctggattgcg cgtaactacg cttcttctgt cattcccatt atctttattg
    25561 tgttgttagc tagccaaatt cagaagccaa ttaaaaagtt agtacctgag atgatcgcga
    25621 atttcttcgt tccattcttc accgttctta ttacaatgcc cttaggtttt ttactcgttg
    25681 gaccagcatt cacattcgca actgatattt taatggctgg atttgaaaca cttttagcac
    25741 tttcgccagt taattatgga gcaatcgtag gcttcttctg gcaaattctg gtgatgtttg
    25801 gtctccattg ggcaatcgta ccaatgggat tgatgcaatt ttctgtgaat ggctggcaaa
    25861 atatcatgac acctgttgca gtagtgtctt ttggacaaac tgcagcactt actgcactct
    25921 actttaagct tagaaaccca aaagacaaag caatcgcaat gccagccatt gtttctggta
    25981 ttgtggggat tacagagcca gctatttatg ggtttacatt gccacgtaaa aaaatattta
    26041 tttttacctg tgtcggtggt gcgttagggg gcgcgtatag tgggttaatg aatttaactt
    26101 cttggaatca aggtggacta ggcatcttta cgattcccaa ctatattaga ccagatggtg
    26161 atttaacaga tgtgattaat gtattaattg ggatcgccat tgcgatggtg gtatcctttg
    26221 cgctgacttt tttcttttgg aaggatgaag caggtgaaac agatgatata cagaaaagat
    26281 cgggtaaaga aattgtaaaa acaccgatac aaggacaaat cgctccacta aatgcagcga
    26341 aggatgcagc ttttgctcaa ggaacattag gtcgagggat cctgatctac cctgaaaaag
    26401 gagaagtacg tgcccctttt gacggaacag ttatgaccct gttcccgacg aaacatgcaa
    26461 tcggaatggt ttctgaaaca gggctggaat tgctgattca tgtcggattg gatactgtgc
    26521 agttggaagg gaaatatttt gaaagcttag tgcagcaagg agaaagagtg aaacaaggcg
    26581 acctgttgct acgcttcgac aaaaagaaaa tcgaaaagga aggatacagt ttagaaacac
    26641 ctgtgatcgt caccaattat acggattatt tggatatttt ggaaaaccaa ggggagacgg
    26701 tcgggccaga cgatgcactt atcaccgcac tgacctgaac ggttaggtga agaatggact
    26761 aggcttaact attcttttta ttccacttct ttattttcaa aattgaaagg ctctttcatg
    26821 atggctgagc tgatagggcg tttatcgaat ttttgaccga cagaaattag atggactaaa
    26881 ttctgctgat aattttctgc aaaaacacaa ctatataaca cgtctagaag ataacaaatt
    26941 gatgtattga tcgtaaaatt accaattttt gaatacagtc gctcgcgtgt cgtaagtcgc
    27001 aaagcggctg tactcattgc agatagcgtt gaatcaccga tactggtcaa agctaaaatt
    27061 ggaacatcat tttgtttcaa tatttctgcg gtacgaagga tcacattgtt ttcacctgta
    27121 taagaaatca gaatcccgca catatcgctc gtgcaattgt acgcttcata gaatgattca
    27181 ccaaaagtgg tgacaattgt gacatccatt ttgatgcgct tcattttcag catgaaatct
    27241 tgagaaatca aagtattcga gttactggcg aagatcacga ttttttttgc ctggagcagt
    27301 aaatacttag ctttttgcag ttggtcatga tgaatgagag aaagtgtatc ttgaatcgtc
    27361 atctgttcta aagaagccat tttatttgcg atcgtcataa taccgtctgt ggtggaaaaa
    27421 ggaagattcg catctacgtc ttgaaaattc ccttcaagat aggctgtttc agctaaaaaa
    27481 gcattacgaa aactgaccca gccatcaaac cccatttttt ttgctacacg gatgagtgtg
    27541 gacgggtgga cataacatcg ctcagcgatc tcttggatgg tcatttcgcc aagtgctgga
    27601 gaatcgctta agagaaactg gatcacttca ttttctgaag gagaaaagga gatttctttg
    27661 attttttcac gtaataacat gtagatacct tcttcttatt tttttacgta aattataact
    27721 tttttgaaaa tgatttgtaa acggatttat actatataac ttaaaataga cattttttga
    27781 caagatattt acaaaaatcc actagaaaac agtaactttt gtaaatgtta ctggaaagaa
    27841 acggatttct attgtttgtt ttgtttacaa aaaagataat taaagtgtaa aaaagtaaag
    27901 gagtgagaac atggcaaaag gaatcaaaat cgctacgatt ggtggaggca gcagttacac
    27961 ccccgagttg atggaaggat ttatcaaaag atatgaggaa ttaccgatac gagaaatctg
    28021 gctcgtagat gtagaagaag gaaaagaaaa gcttgatatc gttagtcaga tgtctcagcg
    28081 tatgtgggat gcttctccgt atgaagtcaa gatctatgca actctggatc gggaagaagc
    28141 attgaaagat gcggattttg ttacgactca gtttcgtgtc ggtcaattag atgcacgaat
    28201 caaagacgag cggatcccta gttattacgg gatgatcgga caagaaacaa atggtgctgg
    28261 cgggatattc aaagcttttc gtaccgtgcc agtggtcttg gcaatcgttg aagacatgaa
    28321 gcgtttatgt ccaaatgctt ggctgatcaa tttcgcgaac ccaagtggga tggtgacaga
    28381 agcagttatc agatatggta aatgggataa agtgattgga ttatgcaatg tgccagtaat
    28441 ggcgatgatg acagaaccag caatgcttgg caagaaaaaa gaagagctga tctacaagtt
    28501 tgccggtcta aatcatttcc attggcacaa agtagcagat aataaaggaa atgaccgcac
    28561 ggcagaattg attgatcgtt tatacgatga agacaatgga ttgccgaaaa atatctttga
    28621 tatcccgttt ttcaaagaac aattaaaaca aatgaacatg atcccttgtg gctaccaccg
    28681 ctattactat cgtgaagaag aaatgctgga acatgcttta gaagaatatc aaacgattgg
    28741 tacaagagcg cagcaagtga aagaaacaga agcagagctg tttgaattat acaaagatcc
    28801 agaattagac cataaacctg aacaattgca aaaacgaggt ggcgcttatt attcagacgc
    28861 tgcctgtgaa acgattactt caatctatgg aaataaagaa acacagatcg ttgtatctac
    28921 aaagaatgat ggagctgttc ctgacctgtc ggcagattgt gttgtagaag tcactgccta
    28981 tgttggcgca caaggagcga gaaatgtagc gtttggttct cttcctgctg ctgaaagagg
    29041 ctggttgcag gtaatgaaga atatggaatt gctgacgatc gaagcagctg tgactggtga
    29101 ttatgggaca gccttacagg cgtttacgat caatccactt atacgatcag gaaagacagc
    29161 aaaacggatc atggatgagt tgtttattgc acaccagcag tatttaccgc aattcaagga
    29221 aacaatcggc cgattaaaag aagaaggaat cgaagttcaa gatgaactgg caagagaatt
    29281 atcaagtaat acacatataa tggaggaagt ataatgggat tcagaaaaga ttttttatgg
    29341 ggcggtgcta cagcagccaa tcaatgtgag ggcggttatg atgaaggtgg acgcggacta
    29401 gcaaacgtag atgttgtgcc aatcggaaaa gaccgttttc ctgttatcac cggaaagaaa
    29461 aaaatgtttg aatttgatga ggaccatttt tatccagcaa aaattgcaat cgatatgtat
    29521 catcgttata aagaagatat tgctttgttt gcagaaatgg ggttcaagac ttatcgaatg
    29581 tccatcgcct ggagtcgtat ttttccaatg ggggatgaga aagagccgaa tgaagctggc
    29641 ttgaaatttt atgaggatgt ctttaaagaa tgccaaaagc acggaattga gccacttgtg
    29701 acgattacgc attttgattg tccaatgcat ttgatcaaag aatatggtgc gtggcgttcc
    29761 agagaactcg ttggttttta tgaaaatctg tgtcgagtca tcttcaatcg ctataaagga
    29821 cttgtcaaat attggctgac attcaatgag atcaatatga tccttcatgc accattcatg
    29881 ggcgcagggc tgtattttga aaaaggagaa aatgaagaac aaatcaaata tcaagcggca
    29941 catcatgagt tggttgcaag tgccatcgca acgaagattg ctcatgaagt agatccggag
    30001 aacaaagtag gctgtatgct ggcagcagga gcatattatc catacacttg caatcctgaa
    30061 gatgtttggg attctagaaa atcagatcga gaaaattatt tcttcattga tgttcagtca
    30121 cgaggagaat acccagctta tgcattgaaa gaaatggaac gaaatggcat tcagatcgaa
    30181 atggaaccag gggatgccgc attgctgaaa gaacatactg ttgattttat ctccttttct
    30241 tattattctt cccgagtttc gactaccgac aacgaactct tggaacagac tgcaggaaat
    30301 atctttgctt ctgtcaaaaa tccatatctg caagcaagtg aatgggggtg gcaaattgat
    30361 ccattaggct tgagaataac gatgaatgat atttatgatc gttatcaaaa accattattt
    30421 attgtagaaa acggcttagg tgcagtcgat acgccagatg aaaatggtta tgtggaagat
    30481 gattaccgaa tcgattacct ggcagcgcat atccaggcga tgaaggatgc agtagaacta
    30541 gacggagtcg atctattagg ctatacgact tggggatgta ttgatttagt atcagctggt
    30601 accggtgaga tgaagaaaag gtacggattc atttatgtcg atcgtgataa ccaaggaaat
    30661 ggcacattag cccgttcaaa gaaaaaatca ttcaactggt ataaaaaagt aattgattca
    30721 aatggagaaa atctttcgaa cgattgatca atgatttata aaagtctatt gtttttcagc
    30781 ggatttttcg agtataataa agctattcga gaaacgcaag cagaacaata gacttttttt
    30841 cgcattggct gtaaagtatg cttacttgat taagtaaagg agaatctaca tatgtatgat
    30901 gtaatcgtta ttggcgcagg tcctgctggg atgactgctg ctttatatgc ttcacgttca
    30961 aacttatccg tattgatgat cgaacaaggt gcccctggcg gccaaatgaa caatacggca
    31021 gaaatcgaaa attatcctgg attcgattcg atcatgggcc ccgatctagc ttataagatg
    31081 tatgaaagtg tctcaagatt tgggacagaa aatgcttatg gaatcgttca agatatcaag
    31141 gatcacggca gccataaaga agtcatctgt gaagataaaa gttacgaagg aaaaacagtc
    31201 attatcgcaa caggctgtat ccaccgtaaa ttaggcgtac ctggcgagga agaatttgct
    31261 ggacgaggcg tttcttactg tgcagtctgc gatggtgcgt ttttccgtaa caaacgtcta
    31321 gtagtcatcg ggggtgggga ctcagcagta gaagaagcca tctatttgac acaatttgct
    31381 tctgaagtag tgatcgtcca ccgtagagat gaattacgtg cacaaaagat catccaagac
    31441 cgtgcatttg caaatgaaaa aatttccttt atgtgggata cagtcgttga cgaaatcgtt
    31501 ggaaacgaaa tggtagtgac aggtgtgaaa gcacgtaatg tcaaaaccgg caatgaattt
    31561 gatttagcag cagacggagt attcatctat gttggactgg atccattaac tgcacctttt
    31621 agagaagcag gtttgacgaa cgaagctggc tggattccaa cagacaacga aatgaaaacg
    31681 aatatgccag gcgtttttgc catcggagat gttcgtgaaa aagatttgcg acaaatcact
    31741 acagctgttg gtgacggcgg tattgctgga caacaagtgt ataaatactt ggagtcttta
    31801 gaagaaacaa cagcataagt ttaaaaagag tgaaagaacg gttttaattg ttcttttact
    31861 cttttttttt cgcgtgaaat ccactgaatc cgatttatgt gaatacttgc aatcatgctt
    31921 gataaaagaa tcctttcttg atttaagcgt tttttggtcc tcatactttc atatctaata
    31981 agtgaatgct atacttatta agaaccatat ttcagaaaga ggtgttattt tcatgtcttg
    32041 ggaacaagtg tatgaacaat gggtacatga agaaaattta gaagaaaact taaaaaaaca
    32101 attaaatgat ctgggtgaag atcctgaaaa acttgaagat gctttttatg caccgttgga
    32161 attcggtact gcaggcatgc ggggaatctt aggacctggg atcaatcgaa tgaacatcta
    32221 tacggtaaga caagcaacag aaggactagc acgtttcatg gatacacaag gtgaagaaac
    32281 aaaacgccga ggtgtcgcta tcgcttatga ctcacgccat cagtcaccag aatttgcaat
    32341 ggaagcagcc aaaacactgg cacatcacaa tatcccgtct tatgtattcg aaagtctgcg
    32401 tccaacacca gagctttctt ttgcagttcg tcatttgaag acgtttgcgg gaatcatggt
    32461 aaccgcatct cacaacccag cggcttacaa tggatataaa gtctacggag aagatggcgg
    32521 acaaatgcct cctgcagacg cagatgcatt gacgaaatat gtccgtgaag tcagcaatcc
    32581 gctaaaagtc gaagtattat ctgacgaaga agctaaacat agcgggttga tcacgatcat
    32641 cggagaagaa gtggacgctg cttatctaga agaaatcaaa gcagtgacga ttgatcgtga
    32701 attggttgaa acaatgggga aagatttgaa acttgtgtac acgccacttc atggaacagg
    32761 gaaaatgttg ggcgaacgcg cgttgaaaca agctggattc gaacaattcg tactagttcc
    32821 cgaacaagct gtggcagatc cagatttcac tacggtcaaa tcgccaaatc cagaagaaca
    32881 ttcagctttt gaatatgcta tacgacttgg agaaaaagaa ggagctgact tgctgattgc
    32941 aacagatcct gatgcagacc gtttaggcgc agcggttcgt ttgccagatg gttcttatga
    33001 agtattgact gggaaccaaa tcggagcatt gtttgctcaa tatattttgg aagcacatca
    33061 atcaagaggc actttaccag aaaacgcagc ggtattgaaa tcaatcgttt ccagcgaatt
    33121 gcctacagca attgcggaac actacggtgc taccatgttc aatgtgttga cagggtttaa
    33181 attcattgct gaaaaaatcc aacaattcga agaaaaccat tcacatactt ttatgtttgg
    33241 attcgaagaa agttatggtt atttagttaa accttttgtt cgcgataaag acgcgatcca
    33301 agcattgctt ttattagcag aagtagcagc ttactataaa aaacaaggca aaacgttgta
    33361 tgacggcttg caaacgattt ttgaaaccta tggctatttc gcagaaaaaa cgatttctgt
    33421 gacaatgagc ggacaagaag gttctgcgaa aatctctgct ttgatggaaa aattccgtaa
    33481 agaagcaccg acagaatttg ccggagcaaa agttattcaa acagaagact ttaaagaatt
    33541 gacgagaaca gaccgtgaag gaaacgtaga aaaactcaca acaccgccat ccgacgtatt
    33601 gaaatataca ttggaagaaa atggctggat tgctatccgc ccttcaggaa ctgagccgaa
    33661 aatcaagttt tatattggtg taaaaggaag ctctacagaa gacgcagcca aaaaagtagc
    33721 ctcttatgaa gcgattatca aaaagatgac agaagaataa aaaacttgag actgatggaa
    33781 aaagtggtaa actttagaag tcagtctttt ttcaagttgg aggtgaatgg attgccagac
    33841 acgcaaaaat caaaagtaga gaaagtcagt caattattca aaatgttgag tgatcccact
    33901 cgtcttaaaa ttctgctata tctgaaagac ggggaacaaa atgtgacagc aatcacccaa
    33961 gcagtggaaa tggagcagtc tgctgtatcg catcaactac gtttattaag agaaaatcat
    34021 gtcgtcaagt ctcatcgcga gggaaaagcg attttgtata gtcttgatga ttctcatgta
    34081 ctggatattt tgaaccagac actcaaacat gtggaacatc aataacgata ggtgcaaata
    34141 gataaacact ggagtgtgac aacgaaattt cttcgttgtc acactccagt gttttttaag
    34201 aaaaagacaa aaatgatcaa tcgctttttt ctgttgtttc agttccataa taactatgat
    34261 cttctaggtc taaagcattc aaaataagcg aagccgtttc ttcaatagat aaagatgcta
    34321 cattgatcac tacacatcct agtttttcat aaagatcatt cgcaaaatcg agttcagctc
    34381 taattttttc gatatcggaa taagcagtat cagggtttaa tccgtaagag cgcatccgtt
    34441 ctttacggat attatttaaa atatctgggt tattcgttag tcccacgatt tttttaggat
    34501 cgatctccca aagctgtttg ggaatatgtg cttgtgggat caaaggtaaa ttggcaactt
    34561 ttaaattttt gttagctaaa aacaagctca aaggcgtttt ggaagttcgg gatacgccta
    34621 gcaaaacgac atctgcttct aaaaaaccac gaggatcttt cccatcatcg tattttacag
    34681 caaattccat tgctttgatc cgtttgaaat agttctcatt caataaatgg agggcaccag
    34741 gttgccgaat tggcttgata ccagttaaac gttcaatttc tgatatcggt ggcgtcatca
    34801 catcaaaact aaataattga tgttcttcac aaaaagaacg tgttatctcg atcagttctt
    34861 gattgattaa tgtatgcagg acaagtgctt tttcttctaa tgcatcttgc aatgcctgcc
    34921 ttaatgtttt ttcatctgtc acgaacgttc tgcggaatag gttgaactca acggtaggat
    34981 actgagccat agtagcttgc gctagttttg tcgcagtttc tccagcagag tcggagatga
    35041 caaaaaaagt aacgatttct gtagaatcgg aagtcatgga taaaacctca cttgcatttt
    35101 ttttatgttt attataccat actctagaat gcgtacttcg taatcatttt gatttggagg
    35161 aataagtcat gaaaaaacag acattgatcg aacaatcatt agaaacattg aaaaataacg
    35221 gttttaaata tactaaaaaa agagaagcat tgttaactta tttagtgaag cgtaaccgct
    35281 acgtatctgc taaagaagtt tttgactata tgaatcagga attcaaaggg gtaagttatg
    35341 atacgattta ccggaatctc catgattttg cagagatcga tttactggaa gaaaccgatt
    35401 taaatggaga aatgaagttt cgttttcatt gctgtcaggg ggaaatcggc catcaccatc
    35461 attttatctg tacagtgtgc ggaacaacga aagaaatcca tatgtgtccg atgaattatt
    35521 tcgaagaaca gctaggtgga tgcacgatcg aagggcatag attcgagatt ttcggaagat
    35581 gtgaaaattg tcaataagga tttaaataaa ataacatttg ataatttaaa aaaaaagcaa
    35641 gatttccttg acggtcaaaa cagcattaga tataatattt acaggacagt cttgtttttt
    35701 gagatatatt tcaataacaa ttacggttac tttttaagct cggagggagg gaattaacat
    35761 gtcaaaaaca gtcgttcgca aaaacgaatc acttgacgat gctcttcgtc gcttcaaacg
    35821 ttccgtgtca aaagcgggta ctttacaaga atctcgtaaa cgtgaattct acgaaaaacc
    35881 aagtgtaaga cgcaagaaaa aatctgaagc agctagaaaa cgcaaaaaat tctagttctg
    35941 tgatgaattg gagttggtag tgtgtcacta ctaagtagat taaacgatga catgaaagca
    36001 gcgatgaaag cgaaagataa ggaatcttta caagtcatcc gaatgatcaa gtcatctata
    36061 caaaacgagc agattaaaga aggtcacgac ttgacagaag aagaagaact aacggtgttg
    36121 tctcgtgaaa tgaaacagcg acgtgattct ttgcatgagt ttgaagaagc aggacgtgac
    36181 gatttagctg aaaaagtaaa aagtgaaatt gtaatagtcg aaaaatatat gccggaacaa
    36241 ctttccgacg aagaaattcg acaacttgtt caagaagcaa tcactcaaac tggtgcttca
    36301 tcaatgaaag aatttggcaa agttatgggt gcaattatgc ctaaagtcaa aggaaaagca
    36361 gatggaaacc aagtgaatgc gattgtgaaa gaactattac aatcttaatt ttatcattta
    36421 aactgcggac agtgattatc cgcagttttt tgtgttcgta aaaaaagaac taaaaaacag
    36481 ctagaagaaa gaatcttatt ctttcttcta gctgtttttt tcctgtttaa tatctcttat
    36541 gttaaattgt gtttgatttg gttattcttc tggtaactca cttgcttctt gtttatatcc
    36601 tgatacgcga tatacataat aaaagagcaa gctgccagcg taaccaagca acgttgggac
    36661 gacccagcca agacctaatg cagcaaaagg aacataatga tgataaaatc ctagtaagct
    36721 tgctacgaca gtttgctgac tcactaatgc aggcgaattt gccaacatat ccaatacggc
    36781 tggaacggca gaaaagaaca tcgttacttg atagacaaat ggactctttt ggaagaattt
    36841 tgctgttaag gaaagtaaga ttaacgcaag tgacaatgga tacaaaagca tcaatactgg
    36901 taaagaccat tggatgatat tatccaatcc ggcattcgca acgacaaaag agacaaaagt
    36961 cgttaaccgc agccatgtca tataactgac tttagggaac agtttatgga aatcttgtgc
    37021 aaaagaaaca acgagtccca tagcagtagt gaagacacct aatgtgacca ttacccctaa
    37081 gaagctagca ccgaagttac ctaaataaaa attagtgatc tgagaaagtg cagttccgcc
    37141 attttctgat aaagacatct tattcaaact catcgcaccg agaaggacca gaccaaaata
    37201 aatcatgact tctaacgcaa cgctcaggct accagctttt gctgttaatt ctgtgacttt
    37261 tttatcttta aaaccaagat cacgaactgc atggacaaaa gtgacactta aagcaagtaa
    37321 agctactgca tcaaccgtgt tgtatccttc taaaacgcca tttgtcaaag cgttcgtctg
    37381 ataagaatct gcagcagatt ggtttagatt ccccatgggt tggaataaag aaacgacaaa
    37441 aatgatagct aataatgcaa gaaacaagga gtttaaatac tttccgacat atttgaccaa
    37501 acgtgttgga tgtacagtaa ggaaataagc aagtaaaaag aaaagagcag agaataaaaa
    37561 catacctaat gaatcatatt tttcaggcaa aaagggttta gcagccattt caaaagcagt
    37621 tgctgctgtc cgcggtgtac caaagaatgg tccgatcgtt aaatgaacaa ggatcaagaa
    37681 caaggcagca taccattttc cgacaggttt agctaagtca tacagaccat cactttttgt
    37741 cactactaca gctaagatag ctaataatgg gaaaagagcg cctgagatgg caaatcctac
    37801 accagcgctg atccagtttg atccagccat ttgacctaag tgtacaggaa agatcagatt
    37861 acctgacccg aagaacatcc cgaagataag tgaactgacc atcaataatt gcttccatga
    37921 ataagttttt gtttcttcca taaatttttc ctccaataat tatcattttg agtaacaaaa
    37981 taaacgttgc agaaactaga aataccacta atatcagatt ccatgaaaac caccacctta
    38041 aaatataaaa aaagcccttt tccacttggg aaaagggctc tagattctag aacggtacca
    38101 ccttttttcg cttaaaaaag cttcttcatt cacggacgct tttcgataaa gttatccgct
    38161 agcctgataa tggaggcagc cacaatgatc tacgttttcg acattgactc ggaaatgatg
    38221 ttcgtctatt cgatttattg tcatttctca cttacatgac tcactgggaa taaatcactg
    38281 aatagcctac tgttttcctc gacgctttgc tgtatattta tttgttgacg ttataataca
    38341 cctgtttttt ttgaaatgca agaatatttc aaatattttg ttttcttttt ttgaaacaag
    38401 aaaaataccc agagaatact tgctaagtta gacggaatac ttgtcctcta tcttatgcat
    38461 agcttacatg atcagctttt tttattcaaa cgagaccttt agagaatgga agcggctagt
    38521 tttttaacgt ttcttggtac ttatggttaa gcaactcttt tagaaccttt tcttatttgc
    38581 tatatagttt cttctgagta tggtaaaata ggaaagaatt aatcgaaaaa aaggggatgt
    38641 ctatttttga cggaagagtc tagttcttta gagattagat tgacggctgc tgatgatgtc
    38701 agcatgcttt taggtgcaca cgacaagcat ataaaactga ttgaggaaac aacggaaaca
    38761 accatccata cacgtggaga aatcattcag atcattggtg agcaatccca gatttccttg
    38821 gctgcctcag tcattcggac attacaggaa ttgatcaaac gaggaatcca cgtaagtacg
    38881 cccgatgttg tgacggcatt gaaaatgggg caaaaaggta cattagatta ttttgttgag
    38941 atgtatgagg aagagatcgt caaagaccgt aatggaaaac ctatacgggt aaaaaacagc
    39001 ggccaaaaga aatatgtcga atcggtagcc aaacatgata tcgtatttgg cgtaggacca
    39061 gccgggacag gaaaaacttt tcttgcagta gtattagcaa tcgctgcctt gaaaaaaggt
    39121 gaagtgcaaa aaatcatttt gacgcggcct gctgtggaag caggtgaaaa tctaggcttt
    39181 cttcccgggg atctaaaaga aaaagtggat ccttatctgc ggcctgttta tgatgcttta
    39241 taccaaattt ttggattgga tcatacgaac cgattgatgg aacgaggcgt aatcgaaatc
    39301 gcacctttag cttacatgcg ggggcgaaca ttggatgatg cattcgttat cttggacgaa
    39361 gcacaaaaca cgacagtcgc tcagatgaaa atgttcttga cccgtctcgg ttatcaatca
    39421 aaaatgattg tcaatgggga tacaagtcag atagacttgc ctcgagggac gacaagtggt
    39481 cttgttcatg cagaacgaac attaaagcaa atcaagaaaa tcgattttgt taattttgaa
    39541 gcaagtgacg ttgttcggca ccctgtagtt gccgaaatca tcaaagctta tgaaaaggca
    39601 gatctccatc aagaataagc tttgcttagg aggataagca catgttgaat aaaacactgc
    39661 agaaactaca agaaaaactt ggaaaggcag cattgccttt cctgctgttc ttgtttttta
    39721 tcattatctg cggcgttaca tttagtagtg tcaaacaaaa ggtcaatgat ttcagagaag
    39781 gccaagtagc agaagaaagt atccgtgcga acaaaacgat cgagaacacg gaagaaaccg
    39841 aacaaaaaag aaaactggca gcagaagcag tcactccaga atacacttac caaaaagatc
    39901 ttgcagatga ccagaacaat cggatcaagc aactatttga attgatcgat aagacgaatg
    39961 atgccatcaa caaatcttat gacgaaaaga ttgataaggc aaaggaagat gaaaatatcc
    40021 caaagcctac tacagaagag cggatcgccg cgctgaagaa aaattttgaa aatgtgaatg
    40081 cagaaaatgt tgtgttttat caaaaactac cgaacaattt ttattcgacg atatttgaaa
    40141 tgactgaaac tgagattcat actgtgaggg atgagagtct gaagctcatt gacgaacaga
    40201 tgagcaaaca agttcgtgaa agtgaattgg aagcttttaa acaagaagca gaagagcaaa
    40261 tccaatattt gaatgtcaca ccagcacaac aacaaatgat tcgctactta gtggatcaag
    40321 gtatcgtagt gaatgacgta ttgaatgaga aaaagacaga agaattgaaa caatccgcac
    40381 gagaagctgt acagccagtg atgatcttcc aaggagaaat cattgttcgt gaaggtaatc
    40441 aaatcgatgc ttcagctatg aaaaaattgg aattactagg actgactaat caaacaactt
    40501 cgatttttcc gctaattgcc atggttttag ctgttttgct tcaaatcggc gtactgattt
    40561 ataattcact tcaattccaa aatgcaggag aaagaacaaa atacgtgctt ttctatgtga
    40621 cagctatgtc agtcagcata gtgctgatga aatttttcca attattccaa acggaacaag
    40681 ctacttatat cccgctgttt tatcccgctg cttttgcacc acttgtttta agctttttct
    40741 tgaatcgaag agcagggatc atggctggta ttttccaagc agtatccgca cttttcattt
    40801 tttatgattc gattggcacg aactttctaa cgattatctt gatgtcttat gttttctctg
    40861 ggctcatggc aacgattgtc agacgcaaac ggatctcaga acaaggatta tctgctgcca
    40921 tgtgggtcat tatttttcct gtgatgatgg atgtcatttt gatcgtctat caaggaatga
    40981 gctttggtga tgcaacgact tggttaatgc tcgtctgcgg gttcactggt gcactcttct
    41041 cattcttgct gacgatcggt ctacacccat atattgaatt gatggtcaat gatgacagtg
    41101 taattgtatt aaatgaactc agcaatccaa atcatccttt attgaaacag ttgctggaag
    41161 aagcgccagg tacttatcat catagtatga tggtagctaa tctaagtgct aacgctgtag
    41221 cagaaatcgg cggacgttct ttgctaactc gagtagcttg ctattatcat gatatcggca
    41281 agatcaaaca tgctagcttt ttcgttgaaa acttgccttc aggagcggaa aacccgcaca
    41341 atttcttatt gccagaagac agtaaacata ttatctttgg acatgtgaca gatggagcca
    41401 aaatattgga agattataat atgccgcaaa tggtgatcga tatttgcaaa cagcatcatg
    41461 gaaccacgct aatgcgttat ttctacatca aagcgaaaga acgcaatccg gaagtaacag
    41521 aagagcaatt ccgttatcct ggaccaaaac cgcaaagtcg tgaagcaggg atcgtcaata
    41581 ttgctgacag ttgtgaagct gcagtacggg caatggatca tccgacgagc gaaaaaatcg
    41641 aaagttttgt ccataatctt atcgaagagc gtatttccga tggtcaatta gacgatagtg
    41701 gactgacctt gaaagaaatc cgaaaagtgg aaaaatcatt aatcagcggt ttaagtagca
    41761 ccttccattc tcggatcaaa tatcctaaaa tgaaaacaga agttgagaag ataaaggaag
    41821 aacaagaaga atagaaagaa gcgatgtata atggatatta cctttatgga tgaaacaaac
    41881 caagtctcag aagagaaaat gaaagaaatc gatgacttgc tgcaatttgc agcatcttat
    41941 ttaaagctgc cagaggaaac agaaatgtct gttactttca tggacaatgc ggcaatccaa
    42001 gtaatcaatc gtgattaccg tggaaaagat gcaccgacag acgtcatcag ttttgctctg
    42061 gaagaagaag gcgaagacga aatcccagtg atttttgaag atggagagaa tccattacct
    42121 cgtgtactag gagacatcat gatctctatt gaacgtgctg ctgaacaagc agaagcttac
    42181 ggccattcat atgatcggga acttggcttt ttagcggtac atggattctt gcatatcaac
    42241 gggtatgacc atatgacacc agaagatgag aaagaaatgt ttggtttaca gaaagagatc
    42301 ttggatgcct atggactcaa aagataaaaa cgtagagaaa aacaaacatt tcctgatgtc
    42361 tgtggaattt gctgtccaag gagtcaaaac cgtttttgag gaagaacgca atatgaggaa
    42421 acatgttgcg ttcggtattc ttgctttatt tatgggcgtg attttccagc ttgatcggat
    42481 agagtggtta tggctgcttt tagctgtttt tctcgtttgg atagtagaga tcatcaatac
    42541 tgtttttgaa aatgtagtgg acatgtttac ggattttcat tttcatccga ttgggaaaaa
    42601 aatcaaagat atggcagctg gagcagtttt agtgaccgct tgttttgctg tcatcattgg
    42661 gttgatttta tttgtcccta aaatatatca tttgttgttt aattaaaaag gagaacgtat
    42721 atgccagaac ataaatcagg gtttgtcgca atcgtcggcc gcccgaatgt aggaaaatcc
    42781 acattattga accgaatcgt gggtcaaaaa attgccatta tgagtgacaa ggcacagaca
    42841 actagaaata aaatccaagg agtatatact acaccagaag ctcagctgat ttttatcgat
    42901 acaccaggaa tccataaacc aaagcatcgt ctaggagatt ttatggtaga agcagcttac
    42961 agtgcgttga aagaagtgga tgcagtctta tttatgatca gtgctgatca aaaacgcggc
    43021 cggggagacg attttattat tgaacgtcta aaaaacgtgc attctcctgt ttatctgatt
    43081 atcaataaaa tcgataagat ccatccagac gagttgctgg gaatcatcga agattattcg
    43141 acgcagatgc cttttgcaca agtgattccg atctctgcta cagaaggaaa caatgtcgaa
    43201 cgcttaatgg atgtattagt cagtgaaatg ccagagggcc cacaatattt tccagatgat
    43261 caagtgactg atcatcctga atacttcatc gtttctgaat tgatccgtga gaaagtcttg
    43321 tttttaacac gagacgaagt gcctcattct gtcgcagtcg ttgttgattc gatgaagcga
    43381 aacgagaatg ataaaatcca tatccaggcc acgatcatcg tcgaaagaga tagccaaaaa
    43441 ggaatcatta tcggcaaagg cggaaaaatg ctgaagcaag taggaacgaa agcaagaaag
    43501 gatatcgaaa atcttttagg agacaaagta tttctagaac tttgggtcaa agtccaaaaa
    43561 gactggcgag acaaaaaagt ctatctgcaa gacttcggct accgaaaaga tgaatactga
    43621 tattctgaac ttcttatagg ttaagtatag aaataaactg gataaaaatc cgcacgttga
    43681 gaaaaacggc ggaagatcga aacataaata atctggatcg gcagaatctg cttttccaga
    43741 tttatttttt aggagggaga atatgagcca gcttgcagaa tcgaaaggct tgattttatc
    43801 tagccgtaat tacaaagaaa aagataaatt agtcaaaatc tttacggaat cttctggcaa
    43861 aatgatgttt tatatcaaag gaatccatcg gcaaaatcag ccattagctc cggctttgct
    43921 cccctttacc gaagcagtct atatcggtaa ttttcgaagt gaaggtttgt cgtttttaag
    43981 cagtgtcaaa gacgtccatg cgtttcggaa catccaagaa gatatctttt tgagcggtta
    44041 tggtacctat ttgctaaatc tagtagatgc agcaatcgaa gatcatcaat atgacccgca
    44101 tttattccaa tttacgcaac aagctctgca gcggatggat caaggagatg atgcagaaat
    44161 catcacgaat atctttgaag ttcaaatact gcaacgcttc ggaatcgcgc caatttggac
    44221 tcactgtgtc gtatgcggag aaacaaaagg aaaatttgac tattcttcca aatatggcgg
    44281 tgtgatatgc gagaaacact ggccaatgga cgaacaccgt tatcatgcag atcctcgtgc
    44341 tgtttatttc gtccgaatgt tttcggctat ttcttatgat aagatcagtg gaatccactt
    44401 gaaagaagaa acgaagcagg caatccgtga cctcattgac cagttgtatg atgaatatgt
    44461 cggtattcat ctaaaaagca aaaagttcat tgatcaaatg aagtcttggg cacacgtatt
    44521 aaagacgcca gagaaaaata tgcctgaaaa agagatacct gaaaaagaag aataaatgaa
    44581 agatacaaca aaaaaatcaa aactatttga caaatacagg gacttccgtc tattattaac
    44641 cgtagattaa atagatcgtt cactgagagg atctattata taaacaagaa aactgcaaaa
    44701 tgaatacgta cattgaccaa gatcagtaaa aaacacgtgg tttagcgagt tcgggagagt
    44761 ggaagccgga cccaaacgat ttttgaagag gcacttgcga gtacgataaa tgaagctgcc
    44821 gaatctttat tcggaagtag ggtggaaccg cgaaattatt cgtccctatg tctgtaatca
    44881 gacataggga ctttttgtcg ttttctttcc tgtattctta ttgacagcaa cgcttaaaaa
    44941 ttgaaagggg caaaacagat gagtaaaaaa ttgaccgtcc aagatatgat tttaacatta
    45001 caaaaatttt ggtcatcaaa cggctgcatg ctgatgcaag cttatgatac agaaaaagga
    45061 gcaggtacga tgagcccata tacattctta cgggcaatcg gaccggaacc atggaatgct
    45121 gcttatgtag agccatcccg ccgaccagct gacgggcgtt atggagaaaa cccaaaccgt
    45181 ttgtatcagc atcatcaatt tcaagtcgta atgaaacctt cacctgaaaa tatccaagag
    45241 ctttatttag aaagcttgcg tcttttagga attgatccat tagaacacga tattcgtttt
    45301 gttgaagaca actgggagaa cccatcgatg gggtgtgccg gtgtgggttg ggaagtatgg
    45361 cttgatggga tggagatcac acaattcacg tacttccagc aagtcggagg actaccttgt
    45421 aaaccagtta cttctgagat cacttatgga ctagaacgtc ttgcttcata tattcaagaa
    45481 gttgaaagtg tctatgatct ggaatgggct gatggcgtga aatatggcga gatcttcaaa
    45541 caaccagaat atgaacattc caaatattct tttgaagtaa gcgaccaaga cttgctacta
    45601 agtaattttg accgttttga aaaagaagct aaacgctgta tcgatgaaaa tcttgttcat
    45661 ccagcgtatg attatatttt gaaatgcagc catacattca acttattaga tgcccgaggt
    45721 gcagtatccg taacagaacg agcaggttat ctttcccgta tccgcaacat ggctcgtgct
    45781 gtagccaaaa tctttgtggc agaacgcgaa aaattaggat tccctttatt gaataaaaac
    45841 acagcaaatc cagaaaacat gaaggaggct gaataagatg gcaaaagact tattacttga
    45901 aatcgggctg gaagaaatgc ctgctcatgt tgtcacacca agcatgaaac aattagaaga
    45961 aaaaacagca aaatttttag atgaaaacca attgacttat gatacgatcg aaacattttc
    46021 cacaccgcgc cgtttagcaa tcaaagtaac aaatattcca gaacgacaag cggacagcga
    46081 agaagaagtc aaaggaccag ccaaaaaaat tgctttggac gcagatggaa actggacgaa
    46141 agcagctgaa ggatttgtcc gaggacaagg tctgacgaca gatgctatca cttttagaga
    46201 attaaaaggc gtggaatatg tctatgtaac gaaatacact cacggcaaag aagcaaaaga
    46261 agtattgaca ggtttagcag atgtcattaa aagcctcact ttcccagtaa cgatgcattg
    46321 ggcagaatac gattttgaat atatccgccc tattcactgg atcgtggcat tgttagatga
    46381 cgaagtaatc ccattcgaaa tcttggatgt caaaacaggc aaagcctctc gaggtcatcg
    46441 tttcttaggc gaagatgtaa catttacgca tgcaaaagaa tacgaagaaa aattaaatga
    46501 acaatttgtt attgcttcac cgcaaaaaag aaaagaaatg atcatcacac aagcaaacga
    46561 attagcagaa aaaaatcact ggatcattga tctagatgaa gatttactag aagaagtcaa
    46621 caatctagtc gaatatccaa ctgtcttttc tggcgacttc gaagaaaaat atctatctgt
    46681 tcctgaagaa gtactagtca cttctatgaa agaacatcaa cgttatttcg aagtacggaa
    46741 cgatcaaggt atgttgcttc ctcattttat ttctgctcgt aatggcgatc gggtaaaatt
    46801 ggaaaatgtg gtacgaggca atcaaaaagt attgactgct cgtttagaag atgcggaatt
    46861 cttttataat gaagacaaga aagcttcaat cgaccaatac gttgaaaaat taaaaactgt
    46921 tactttccat gaaaaaatcg gtagcatcta tgagaaaatg caacgggtac aagtcatcgc
    46981 tcgcatcata ggcgaacaag taggactatc tgaggaagaa ttgatggatc tgcaacgcgc
    47041 tgctgaaatc tataaatttg atctagtaac caacatggta ggagaattcc ctgaactaca
    47101 agggatcatg ggagaaaaat atgctctgct taaaggcgag aaaccagccg tagcaacagc
    47161 gatccgtgaa cattacatgc ctatatccag tgaaggagat ctacctgaga ctacagtagg
    47221 ttctgtttta gcgattgctg ataaattaga tagtatcttt tctttctttg cagttgggat
    47281 gatcccaagt ggctcaaacg atccatatgc tttgcgccgt caagcatatg gtgtcgttcg
    47341 aatcatcgaa tcgaaaaaat gggcctttcc tttgtctgtt ctgcaagaaa cgattagtga
    47401 agttatcagt aaagatacgg atcgttttgg cattggcttg tcagcgggac aacaacaggt
    47461 gatcgacttt atcaaaggcc gtctgcgcca attattgaca actaagaata ttcgtcatga
    47521 tgtcatcgaa gctgttttga acgcagaaca aaaagatctg acaaaagtat ttgcagcagc
    47581 acaattgttc aagcagcatc ttgcagatga agacttcaaa ccatcgatgg aagctttgac
    47641 acgtgtcgtg aacttagcga aaaaagcgga gcttgaaaaa caatcagaag tagaccctga
    47701 actgttcgaa aacgaagcgg agaaagaact gcacaaagca gtagaggcaa tgaaaacaag
    47761 ctttgctgac caaacgatca acgaaaatta tgatcagctt gtaagccttc gcccactgat
    47821 cgaaaattat tttgatcaga cgatggtcat ggcagaagaa ccagcagtac gtaagaaccg
    47881 attaacgcaa ttaagtcaaa ttgctgccat ggctttgtca ctagcaagtt tagatcaaat
    47941 catcacaaaa taatttctaa tatgtaaata aaccagagaa caggcacaaa ataggctatt
    48001 tctctggttt atttgttata aatataaata ac
//
LOCUS       DAXLPC010000010        47470 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.010, whole genome shotgun sequence.
ACCESSION   DAXLPC010000010 DAXLPC010000000
VERSION     DAXLPC010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.010"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(55..789)
                     /locus_tag="ACF3UE_000550"
     CDS             complement(55..789)
                     /locus_tag="ACF3UE_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFD3634007.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1116..1526
                     /locus_tag="ACF3UE_000551"
     CDS             1116..1526
                     /locus_tag="ACF3UE_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFD3634008.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1519..2220
                     /locus_tag="ACF3UE_000552"
     CDS             1519..2220
                     /locus_tag="ACF3UE_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFD3634009.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2220..3806
                     /locus_tag="ACF3UE_000553"
     CDS             2220..3806
                     /locus_tag="ACF3UE_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3634010.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3825..4046
                     /locus_tag="ACF3UE_000554"
     CDS             3825..4046
                     /locus_tag="ACF3UE_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFD3634011.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4043..4804
                     /locus_tag="ACF3UE_000555"
     CDS             4043..4804
                     /locus_tag="ACF3UE_000555"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFD3634012.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5184..5693
                     /locus_tag="ACF3UE_000556"
     CDS             5184..5693
                     /locus_tag="ACF3UE_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFD3634013.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5768..6307)
                     /locus_tag="ACF3UE_000557"
     CDS             complement(5768..6307)
                     /locus_tag="ACF3UE_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFD3634014.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="ACF3UE_000558"
     CDS             complement(6447..7058)
                     /gene="rpsD"
                     /locus_tag="ACF3UE_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFD3634015.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7320..8171
                     /locus_tag="ACF3UE_000559"
     CDS             7320..8171
                     /locus_tag="ACF3UE_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFD3634016.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8199..8834
                     /locus_tag="ACF3UE_000560"
     CDS             8199..8834
                     /locus_tag="ACF3UE_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFD3634017.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8854..9627
                     /locus_tag="ACF3UE_000561"
     CDS             8854..9627
                     /locus_tag="ACF3UE_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3634018.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10035..10832
                     /locus_tag="ACF3UE_000562"
     CDS             10035..10832
                     /locus_tag="ACF3UE_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFD3634019.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10810..11223
                     /locus_tag="ACF3UE_000563"
     CDS             10810..11223
                     /locus_tag="ACF3UE_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFD3634020.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11207..13852
                     /gene="mutS"
                     /locus_tag="ACF3UE_000564"
     CDS             11207..13852
                     /gene="mutS"
                     /locus_tag="ACF3UE_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFD3634021.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13870..15978
                     /gene="mutL"
                     /locus_tag="ACF3UE_000565"
     CDS             13870..15978
                     /gene="mutL"
                     /locus_tag="ACF3UE_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFD3634022.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            16000..16560
                     /locus_tag="ACF3UE_000566"
     CDS             16000..16560
                     /locus_tag="ACF3UE_000566"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFD3634023.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16645..18633)
                     /gene="treP"
                     /locus_tag="ACF3UE_000567"
     CDS             complement(16645..18633)
                     /gene="treP"
                     /locus_tag="ACF3UE_000567"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFD3634024.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18856..19569
                     /gene="treR"
                     /locus_tag="ACF3UE_000568"
     CDS             18856..19569
                     /gene="treR"
                     /locus_tag="ACF3UE_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFD3634025.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19646..20092
                     /gene="msrB"
                     /locus_tag="ACF3UE_000569"
     CDS             19646..20092
                     /gene="msrB"
                     /locus_tag="ACF3UE_000569"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFD3634026.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20262..20864
                     /gene="ruvA"
                     /locus_tag="ACF3UE_000570"
     CDS             20262..20864
                     /gene="ruvA"
                     /locus_tag="ACF3UE_000570"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFD3634027.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20877..21878
                     /gene="ruvB"
                     /locus_tag="ACF3UE_000571"
     CDS             20877..21878
                     /gene="ruvB"
                     /locus_tag="ACF3UE_000571"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFD3634028.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21907..22485
                     /locus_tag="ACF3UE_000572"
     CDS             21907..22485
                     /locus_tag="ACF3UE_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3634029.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22537..23019
                     /locus_tag="ACF3UE_000573"
     CDS             22537..23019
                     /locus_tag="ACF3UE_000573"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFD3634030.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23136..23510
                     /locus_tag="ACF3UE_000574"
     CDS             23136..23510
                     /locus_tag="ACF3UE_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634031.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(24188..25540)
                     /gene="brnQ"
                     /locus_tag="ACF3UE_000575"
     CDS             complement(24188..25540)
                     /gene="brnQ"
                     /locus_tag="ACF3UE_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFD3634032.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            25687..26277
                     /locus_tag="ACF3UE_000576"
     CDS             25687..26277
                     /locus_tag="ACF3UE_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFD3634033.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(26405..27754)
                     /locus_tag="ACF3UE_000577"
     CDS             complement(26405..27754)
                     /locus_tag="ACF3UE_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3634034.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(27922..28662)
                     /locus_tag="ACF3UE_000578"
     CDS             complement(27922..28662)
                     /locus_tag="ACF3UE_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD3634035.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(28675..30267)
                     /locus_tag="ACF3UE_000579"
     CDS             complement(28675..30267)
                     /locus_tag="ACF3UE_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFD3634036.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     regulatory      complement(30405..30579)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            complement(30835..31131)
                     /locus_tag="ACF3UE_000580"
     CDS             complement(30835..31131)
                     /locus_tag="ACF3UE_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634037.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            31307..32032
                     /locus_tag="ACF3UE_000581"
     CDS             31307..32032
                     /locus_tag="ACF3UE_000581"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFD3634038.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            32025..32867
                     /locus_tag="ACF3UE_000582"
     CDS             32025..32867
                     /locus_tag="ACF3UE_000582"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFD3634039.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            32870..33391
                     /locus_tag="ACF3UE_000583"
     CDS             32870..33391
                     /locus_tag="ACF3UE_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFD3634040.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(33644..34207)
                     /gene="def"
                     /locus_tag="ACF3UE_000584"
     CDS             complement(33644..34207)
                     /gene="def"
                     /locus_tag="ACF3UE_000584"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFD3634041.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            34458..34727
                     /gene="rpsO"
                     /locus_tag="ACF3UE_000585"
     CDS             34458..34727
                     /gene="rpsO"
                     /locus_tag="ACF3UE_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFD3634042.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            34915..37041
                     /gene="pnp"
                     /locus_tag="ACF3UE_000586"
     CDS             34915..37041
                     /gene="pnp"
                     /locus_tag="ACF3UE_000586"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFD3634043.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            37551..37817
                     /locus_tag="ACF3UE_000587"
     CDS             37551..37817
                     /locus_tag="ACF3UE_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3634044.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            37961..39952
                     /locus_tag="ACF3UE_000588"
     CDS             37961..39952
                     /locus_tag="ACF3UE_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFD3634045.1"
                     /translation="MATTHNTKKISMTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            40306..41607
                     /locus_tag="ACF3UE_000589"
     CDS             40306..41607
                     /locus_tag="ACF3UE_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFD3634046.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(41737..43107)
                     /locus_tag="ACF3UE_000590"
     CDS             complement(41737..43107)
                     /locus_tag="ACF3UE_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFD3634047.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVNPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(43289..43612)
                     /locus_tag="ACF3UE_000591"
     CDS             complement(43289..43612)
                     /locus_tag="ACF3UE_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFD3634048.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(43937..44545)
                     /locus_tag="ACF3UE_000592"
     CDS             complement(43937..44545)
                     /locus_tag="ACF3UE_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFD3634049.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            44875..45591
                     /locus_tag="ACF3UE_000593"
     CDS             44875..45591
                     /locus_tag="ACF3UE_000593"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFD3634050.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            45604..46299
                     /locus_tag="ACF3UE_000594"
     CDS             45604..46299
                     /locus_tag="ACF3UE_000594"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFD3634051.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            46383..47012
                     /gene="udk"
                     /locus_tag="ACF3UE_000595"
     CDS             46383..47012
                     /gene="udk"
                     /locus_tag="ACF3UE_000595"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFD3634052.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        15391 a         8788 c         9878 g        13413 t
ORIGIN      
        1 ataaaaaaac ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc
       61 cataaataat aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac
      121 tggtacccat gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg
      181 tacaagacgt ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag
      241 tgaagcaact aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc
      301 ttggaagaat ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa
      361 gaattcattg acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc
      421 taacacatgg tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat
      481 caattgtcca atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca
      541 agggaataga ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct
      601 gattccacca aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag
      661 catccagtca ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt
      721 acctagaacg attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga
      781 gtaatccata aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg
      841 aaaagcatcg gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat
      901 aaaaaaatga attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt
      961 taaaagttct ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt
     1021 tttctcaaaa attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta
     1081 gtaaaatgaa agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca
     1141 ttattatttt cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc
     1201 ctggaagtat cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc
     1261 ctgaaaaaat cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc
     1321 ctgctggtgt aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac
     1381 tgggagcagt cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag
     1441 gtgtagaagc tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg
     1501 aaatggagga gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg
     1561 actttaggag tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg
     1621 aatcctctcg tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc
     1681 tataaagact ataatatcgg gggcaatttt ttgactatgc tgattactcc tgcgacagtg
     1741 gcacttgcca tccctcttta taaaaacttc cgtttactga aagagaattt ttatcctgta
     1801 atggctgcga ttttagcagg aatagtcgca aattgcttgg ttagtgtagg gttcggttac
     1861 ttcttctctc ttcataaaga gatggtgatc tcattactac ctaaatctgt aacgacggct
     1921 atttctgtcg atttatctca tacgatgggc ggggtgaatg ccgtgacact tgctattgtt
     1981 gtctctacag gtatttttgg ttcgctgatc gccactcata ttttccgcct attcaagatc
     2041 gaaagtccag ttgctcgcgg tgtggcgtta ggaagtactt ctcatgctat tggtacagca
     2101 aaagcaatcg agattggtga aatagaagga atcatttccg gacttgcgat atgcgtcaac
     2161 ggaatattga ccgttttatt gctaccgtta ttctttcagc cttttgctgg cttgttttga
     2221 tgcgaaaacc actattttat gctacaataa ccaaaacgtt cgagcataaa aaaggaggga
     2281 aagacgtgta tttgtcttcc gagtatctta aacaatttga taaagatcta tattataaga
     2341 ttctcctcct agaaagtttt gaggatcaag cttggcatac cgctgcacaa ttagcgcaag
     2401 ttgttcagct ggatgcccgc agcgtgtcga aatacctgaa cgagctgtct aaaaactatc
     2461 agcagtttag cggtaagaca caccctttgt ttacaaaaaa tcaccgttct ggttataact
     2521 tttatgatac gctcgattca attgaacatg agcgtttttt gatctatctc gtgcaaagta
     2581 cgctgaaatt ccagttgctg cacgacattt tttttgaaga attccataca atgtaccaat
     2641 ttgcgcaaaa gcattacatt agtgaatcta ctgctcatcg aaaaatcaat gaatggaaac
     2701 agcaactgca aacttacgga attcggctgc aacgaggtac atatatcgct caaggcgaag
     2761 aagaaatcat tcgactttac ttgcatatga cattctggca gttgtttcga gggaaaatct
     2821 ggccatttga aacgatttct caaatggacg taaagaatat ggcagaacat atcatggctt
     2881 tttttaatgt tcgtctgaac gagatcaaaa aaagacgatt ggaatatatg ctaggtgcct
     2941 tttttttaag aaaatcacag aagcattatg ttgtattgaa tgagaaaaaa agacggctga
     3001 tttctgacaa tctgttgttc cagcgatttt gccaggtcat ggagccggta tttcctaatt
     3061 attttcaagt agaagacgag ttaggcgcat tatttcttgt actgatgact cgtgaagaat
     3121 attatagtga tcctaagata cggaagaaaa tttttgattt tcatcaacaa gcaaaaacac
     3181 cgccctttac agccctttca gaagcaaaag ccgctctttc tctttatcag gaagagcagg
     3241 ggctgccagc agaaaatcta accttcgagg cagaaaacta tttattcagc agtcattttt
     3301 tcgcctatct ttttcctaat gcgaaagaaa cgattgatgg caatagtagt gattttatta
     3361 atcatttagt tattgaaaac aaggaattga aacaatggct cgtacatttt tttgaaagta
     3421 gacacaaaca tcccaatcat ctggcattta aaaatcatgc gtttttgatg gggcggtatc
     3481 tgactgtgtt taaaacatta ggagccttta ctccacagct tccaaagatc acgatccttt
     3541 taatgacaga tttcccatta tttgaagagc aactgttaga ggagggatta cggacatttt
     3601 tccgtaatga gtatcagctg atttttctgc caacagatta tcgggggaga gaagttgatc
     3661 ttctgatttc gacaagtaaa gtccaccgca aaccatgggc ggatcttgac tattttattg
     3721 tgactgaaga actaaaatta attgattaca tccaactatc tcaaaaattt gaaatgattc
     3781 aaaaacaaaa actattaaaa caataacaaa gaaggagaaa aaagatgaca tttgaagaaa
     3841 ttttaccaga attgaaaaaa ggtgcaaaga ttattcgtaa aggatggagt ggatttgaac
     3901 tttatgttgt tctcgtatcc gatgatgaat ttgatggctg tccggtgacg ccgtacttat
     3961 tgatcaaaac aagtgacgaa ggtttttcca gcttcgctcc tacagtttgt gatattttag
     4021 cagatgattg ggcgatcgta gaatgaaaaa ccagtatcca gatctagcta aacaggttgt
     4081 atttatcaca ggagctgctt ctggaattgg tgctgcgcaa gcccgagcgt ttcttgaaca
     4141 agatgctttt gtatttggat tagatcaaaa gttcggtaaa atggaagaaa tttctttgcg
     4201 atttcctgaa acttttgcct acgcactagg tgatgttcga caaatgaaag aactccaaca
     4261 agcggtatcg aaatgccaaa atcattttgg tgaagttacg attttactga atacagcggg
     4321 gatattggat gcctacaaac ccttgatgga aactgacgaa tcgctgtggg atctgattta
     4381 tgagacgaat gtgaaaagca tgtatcagct gacaaaaatc atccttcctg atatgatccg
     4441 ccaaaaaagc ggaacgatca tcaatatggc ttcgattgct ggcttgattg ctggtggagg
     4501 tgggatcgct tatacaagcg cgaaacatgc gattgtcgga tttaccaaac aactcgctct
     4561 ggattacgca ggacagggta tccgagtaaa aggaattgct ccaggagcca tccaaacacc
     4621 aatgaatgcg gctgattttg aagggaaagg tgagatggca gagtgggtgg caaatgaaac
     4681 accagtcaag cgatgggcac agccggaaga agtagctgag ctgacgttat ttcttgcctc
     4741 tcctcaagca agctacatac aaggaacgat catcccaatc gacggcggat ggttgttaaa
     4801 ataaccttgt gtttttttca agcttctgta tgataaaact aaagagagaa acaacggttg
     4861 atgataaaaa aagtcgatga ctgttcccga cattcgatgc cgaacagcca gttcaaaaaa
     4921 ttctttttaa taatcgttaa tattcgaaac taagcggctt ttcacgacct cttgatataa
     4981 acgatattca aaagcttgca actgcggtaa caagtccagc caaatgaaaa atataaggag
     5041 ctatttttat ttgaccattc ttattacttg ttgcagggca gctttttcac taccttctgc
     5101 gacacttcag ttggaatttt cttcccatcc tttggtcgcg gtcattacca agataaaatt
     5161 atcttgcaaa ggagaaatag aacatggaaa aaaataatac ccgttcagcc aaacgctgga
     5221 caacgacaga tgtgactcgg atggcgctag tcactggttt atatgtggca gtgacgctgg
     5281 ttttgtctgt ctttagcttt ggagtgattc agattcgtct ctcggagatg ttcaactatc
     5341 tgtccttgta taacaaaaga tacatcgtcg cggtaacagc gggagtagct ttggctaata
     5401 ttgcttctcc tcttggactg atagatgttg cagtaggaag cgtcagcacg ctgcttgtat
     5461 tgcttatcaa ctataaaatc actagtcgca tcaaaaacat gaaaatcaaa atggccgtga
     5521 cagcatgcgt atttgctttt tccatgttta cagtagctgg tcagctaacg attttatatc
     5581 aactaccttt tttcttgaat tggtgggtga ttgctttagg agaattggca tcaatgattg
     5641 tcggtgggat aattatttat tggatcggta aaaaagtgga tttgtcaaaa taaagatctg
     5701 tttaatttaa aatagggcag catggaagag actgaatgtt gagtcttctt ccatgctgct
     5761 tttttgatta atttgtatga agaaatcgat ttagccgttt tttcatcaag ataccgatat
     5821 aagctgctcc agttgccttg attgcttccg gcagtaaaaa cggcagtagt ccactggcaa
     5881 atgcagttgt aaaagtaaga tcaccactta ttttcagcca gatcgttccg cagatcaatg
     5941 cagcaagaga gcccattaga ttggcaaaga ttgcatataa gtaatgagca tccgttcttt
     6001 cgatcatcca accagttatc cacgtttgta agagaaatcc aatcaaatat ccgccagttg
     6061 gcccaaataa aacagctata cctccagtca tccctgaaaa tacaggaaga ccaatcaagc
     6121 caagtaaaag ataaactcca acagatatca atcctagttt tcttccgaga aaagttgctg
     6181 ttaatccaat agcaaatgtt tgccctgtca aaggaaccaa accaaaagga atggtcatct
     6241 gagaaaggac agaaataatc gcggcaaatt ccgcagcaag tatcaattct ttcaatgttc
     6301 ggttcataac gccctctttt cgttaactta atatttttat ttggttaacg aaattgtaaa
     6361 acaaagtgat tactttgtaa atagaaaata taaaaaaaga ccagctatcc aatagatagc
     6421 ggtctttttc aagaaagctt ttgaaattat aagctttggt tgtagtattc aacgacaaga
     6481 gcttcgtcga tttctggata tagttcgtca cgttctggta aacgagtcaa tgaaccttcc
     6541 aatttttcag cgtcaaagct tacgaatgct gggcgtccaa cagttgcttc tacagcttct
     6601 tttactgtta cgatgttttg tgatttttca cgaactgaga tcacttgacc cacttctacg
     6661 tggtatgaag ggatatcaac gcgtttgcca tcaactaaaa tgtgaccatg gttaactaat
     6721 tgacgtgctt gacgacgagt cgttgcaagt cctaaacggt aaacaacatt gtctaaacgt
     6781 tgttctagta agatcatgaa gttaacacca tgtttacctt ctttgatttt gctagctttt
     6841 acgaacaagt tacggaattg acgttcgttc attccgtaca tgtgacgaag tttttgtttt
     6901 tcagttaatt gcatgccgta ttctgattgt ttgccacggc tattaggtcc atgttgacct
     6961 ggtgcgtaag ggcgacgtgc taattctttt cctgtgcctg acaatgagat gcctaagcga
     7021 cgagaaattt tccatgatgg tcctgtataa cgagacatta aaatttcctc caatgaatat
     7081 aagtttttgg agtaaaataa tccgttgaaa aattcataat catatagttt gttcttcaat
     7141 cttcaccttt gcagccgcgg ttacacaatc gaacccgaga cggggcaaca aactagggat
     7201 gagttattat ttttctgctg cattatttta cacaaattac agtatatgat agatcatcca
     7261 cgaatgtcaa gataattagt acataaaaac gctttacaaa cctaggctgt ctttataaaa
     7321 tgagagggta tgtgcaaatg gaaaaaagcg aaggaagttt aaggagaaaa tcaatgaatc
     7381 cggtatcacc attatttgag aaaatcgatg cttcaattga aaagaaggcg aatctttttg
     7441 aaaacagctt ttcacgttac gctgttcgag cggttctcgc ctgtttgttt ttgactttag
     7501 gaacggctgt ggcatttgcg atcgcgatga agggggaaga tatcgcgcat ggtctaggaa
     7561 agattttata cgcatttatg ttcagctggg gtctggtcat gattctatac atgaacgccg
     7621 aattaggaac atcgaatatg ctttatatga ccgtgggtgt ttttcggcag agacttgctt
     7681 taagtaaggc agccaagatt ctatttgcct gtattttttt caatatgatt ggcggtatat
     7741 tatgtggatt tctaatttct atgactacgc catttcaaga tttaacgttg gacaacttta
     7801 tgttagaatc aatagcagta aaactagcaa aaccttcagc aacgattttg gtggaaggga
     7861 tgtttgcgaa tatcgttgtc aataccgctg tactgatcag catgcggatg aaagaggatg
     7921 tcggaaaagt gatcacagtc gtattcatca ttttcatttt tgctttttta ggatatgaac
     7981 acgtgatagc gaattttcct gcctttacgc ttacttactt tgcttctcac ggacagatgg
     8041 atggaatgac agtcagcaat gtgttacata atttgttttt tgctttggca ggaaattata
     8101 ttggtggcgg tttagtaatg ggactgggat atgcttggct gaatcagtca aaatcatcct
     8161 atgtggacta aaaagtcgtt cattaaaggg gaagtgccat ggaagtttta gtttttccaa
     8221 aaaatgagga aaaagcgtta caaatggaaa agtacatgaa aaatcttttt tcctttgctg
     8281 gagtacctaa gccggaacgc gctcttttac aacaaccgtt actggatgag agcaaaaatt
     8341 tatctatttc tgaagtttta gcttttgttc attattatta tgaacaaatc gaaagagagt
     8401 atcagtatgt agcgatcgat ttagtccaga aaaacatcaa acggcttaca tttgaagact
     8461 tagtcgtatt gttgccacta gttcagaaaa aagaatggtg ggacagcatc gactcttgga
     8521 gaaaagtata cagcacatgg tgtaaagcct acccagagca gcgtgaagaa gtctttcaat
     8581 tgtttgaaaa aaaggaagat ttttggctac gtcgaatagc aatcacgttg caattaggtt
     8641 ataaacagca aacagacaca ggactattga tccgagcaat agacgaagat cgtcaaacaa
     8701 aggaattctt tatccaaaaa gcaattggtt gggcattacg cgattatagt aagaccgatg
     8761 ccgattgggt aaaaagacag ctgacaacag atttgagtaa gttagctgtt cgagaggcaa
     8821 gtaagtattt ataagaaagc gagacgacaa gagatgagac gcaaattatt tgcttttgat
     8881 attgatggaa cgttgttaga ttcaaacaaa caagctttag atagcacaag agaagcattg
     8941 gaaaaattac gcaaagccgg tcatctggtc acgattgcta cagggcggag ccgatttcat
     9001 gcgcaagaga tcattcgcga tcttgatttt acgaactaca ttttatgtaa tggagcggcc
     9061 ggttttttag accatgaaca agtatataag aatttactag atcgcgacca gttggatgcg
     9121 ttcgttcaag aagcgcatca tgagcagatc gatacagctt ttgtcagctt agacaatatc
     9181 aagcgttctt cttccaatga tgtaacggtg atggaagaag cgatgcattc tttcggtgct
     9241 gtcttgcctg aattagatca gttttttgca gaggaacaag aaatatacca agcgttagca
     9301 tttttcgatc aaacatatga tgggaagttc tcttcatatg ataaaattcg atttgtccgc
     9361 tggcatgaga acagtgtaga tgtcgtacct aaaaatggtt ctaaagcagc gacaattctg
     9421 cacttagcag aacaagtagg catccctcat gaagacatca tcagctttgg cgatggacaa
     9481 aacgaccgtg aaatgttgcg catgtcagga attgggatag ctatggggaa tgctgtgcca
     9541 gaagtacaag cagaagctaa gatggtcact gatacaaacg atcaggatgg aatttggaag
     9601 gcattgaaag agttaagcgt gatttaaaag aggttgtgaa aaagctgttc tgcatcaagt
     9661 aataagccca gccaaacaaa aatagctcct cctatttttc gtttttctgg gcttattacc
     9721 gcagatgcaa gctttcgaac accgtttaag gaagaggtcg tgacagaagt ggtcagtttc
     9781 aagaaataag aagggattta cgaaaattgc ttctcaaatt tttgtaaaat tacggcttat
     9841 ttctgaagaa gtagatgaaa caacgtttat tcgggaaatg ggactgtgac aagatgtttg
     9901 tcatagtccc atttttttat tttatttttc aaaactaaga aataccagga aagagttcct
     9961 tttgtttgac cttttctttc ttattgaaaa caactataat atagagtgat gttaaaagag
    10021 aagaggaatt tagtgtgcgg gtattgttta ttggtgatgt agtaggttca atgggacgag
    10081 agatgattac tgaatatctt cctagattga agaagaagta ccgtccgcaa gtaacgattg
    10141 taaatggtga gaatgccgct tctggacgtg gaatcacaga aaaaatctat aaaaaatttt
    10201 tgcaagacgg cgtagatgtc gtgacgatgg ggaatcatac gtgggacaac cgcggaatct
    10261 ttgagtttgt aaatgaagct aaaaagatgg ttcgtccggc aaattttccg gaagggacgc
    10321 ctggacaagg gatggtcttt gtcaaagtga accaagtcga actggcagtg atcaacatgc
    10381 aggctcgttc ttttatggtg gacttggatg atccttttcg taaaatgaat gagctggtag
    10441 aagaagccag aaaacgtacg ccgatcattt ttgtagattt tcatggagaa acaacaagtg
    10501 aaaaacaagc aatgggctgg tttttagatg ggaaagtttc agcagtggtc ggtacacata
    10561 cacacgttca gacaaatgat gcgcgaattt tgccaagagg aacagcgtat ctgacagacg
    10621 ttgggatgac aggtccctat gatggtattt tgggtatgcg cagagaacct gtaatcgaaa
    10681 agtttctgac tgcattacca aaacgttttg aagttgtgga acaaggccga tcgattttaa
    10741 gcggctgtat cttggaattg gatgatacga caggtcatgc aaaagaaatc cagctgattc
    10801 agatcaacga tgatcgaccg ttcatggagt agaaagagag gcagtttttt gcagcaggag
    10861 ccggaaattc aaaaagaagt aaggaaactg acaaaacttt taagagagaa tgaaacgatc
    10921 attcgctaca aagaacttga agaaaagatc cagcaaaacc agtatttagc tgagttgaga
    10981 gaaaaaatca aacaagcgca aaaagatgct gttcattttg cccactatga caaaccagca
    11041 gcagaaaaag aagcaatcaa acaagcggat caattcatgc aagaatttga tcagcatccg
    11101 cttgttgtag cttatagaaa acagctgttg gaagcagatg atctgcttca tcatttaaca
    11161 actatgatac aagaagaaat caatggacaa atagaggagg aaaaacatgc ctcaaaaaac
    11221 taaaaatact cctatgatgg aacaatatct aagcatcaag gcccaatacc aagatgcttt
    11281 tttgttctat cgtttaggag acttttatga actattttac gaagatgcga tcaaagcgtc
    11341 acagcttttg gaattaacgt tgacgagcag aaatcgaaat gcagaagaac ctattcctat
    11401 gtgcggtgta cctcaccatg cagcacaagg atatatcgat gccttgattg aaaaaggcta
    11461 taaagtagcg atttgcgagc aggtagaaga tccaaagacg actaaaggga tggtcaagcg
    11521 cgaagtgatc cagctagtca ctcctggtac agtcatggac agcaaaggat tgtcggcaaa
    11581 agacaacaat tttttaacag ctgtagttag tcaaggaaat gaatttggct ttgcttatgc
    11641 cgatttaagt acgggagaat tgaagacggc tcggttgcat gatgaagaag ctgttttaaa
    11701 tgaagcctct gcattgcaga caaaagaact cgtattaggc agtgagatca ctgataccct
    11761 tcgtgaacag ctaagcgggc gtttagggct agtcttttct caacaaaatg agatggaaga
    11821 aaacgcggaa tttagctttt tgacaagcga actagtcgat ccgctggaaa aagaagcaac
    11881 cggcaaacta ttgacttatt tatcggtgac acaaaagcgg agtttagctc atatccaaaa
    11941 agcagtagaa taccaaccag atcatttttt gaaaatggat tattattcaa aattcaacct
    12001 agaattaagc caatctattc ggactgggaa aaagcacggc actcttctat ggttgttaga
    12061 tgaaacaaaa acagcaatgg gtggccgttt actaaaacaa tggctagacc gtccgcttat
    12121 ccaggcaaaa caaattaaag caagacaaga aatggtcgct tctttgctag acagctattt
    12181 tgaacgtatc gatttgcagt cagcattaac gaaagtctat gatctggaac gcctagcagg
    12241 tcgagtagct ttcggtaatg tcaatgggcg agacttgatc cagctgaaaa cttctttaga
    12301 acaagtgcca atgatcagag ggttgattga aggaatcgat caaggtcaat ggcaaagtct
    12361 gctttcagaa atgcagccga tggaccatct cgtccaattg atcgaccaag ctatccaaga
    12421 tgatccgccg ttacaaataa cggaaggaaa catcatcaaa gatggattca atgagcagct
    12481 cgatatgtac cgttctgcta tgagaaacgg aaagaaatgg ttggcagaac ttgaagcaaa
    12541 agagcgtcaa gaaacaggaa tcaagaactt aaaaatcgga tttaaccgcg ttttcggtta
    12601 ttatatagaa attacaaaag caaatcttgg aaatgcagaa ctggagaagt atgaacgaaa
    12661 acaaacttta gcaaatgcag agcgtttcat cacaccagaa ctaaaagaat tggagacaca
    12721 aatcctcgaa gcagaagaaa aatctgttga tttagaatat cagttgtttt tagctgtgag
    12781 agaagaagtc aaaaaggcta tccagccgct acaagtactt gcaaaagcaa tcagtgcagt
    12841 agatgtgcta caaagttttg caacgatcag cgaacgctat cagtatgttc ggccagaact
    12901 tgtcagtgac aagcatcagc ttctgatcaa agacggacga catcctgtag tagaaaaagt
    12961 attaggacat caggaatata tccctaacag cgtagaaatg gcagaagacg aaatgatctt
    13021 gctgattaca ggaccgaata tgtctggtaa aagtacgtat atgcgacagt tggcattaac
    13081 tgttctgatg gcgcaaatgg gctgtttcgt tccggcaaaa caagcagttt tacctatttt
    13141 tgatcggatt tttacccgaa ttggtgcaag tgacgactta attgctggac aaagtacttt
    13201 tatggtagag atgatggaag ccaatcaagc cctgcgttat gctacgccaa acagtttgat
    13261 tttgtttgac gaactagggc gaggaacagc aacctatgac ggaatggcgt tggcccaagc
    13321 aatcatcgaa tatatccatc gtcatgtaca agcaaaaaca ctcttttcta ctcattatca
    13381 tgaactgacg gtacttgaga aagaacttcc gcagcttaaa aatgtccatg ttggagccgt
    13441 tgaaaaagac ggagaagttg tcttcttgca taaaatgatg gatggacctg cggataaaag
    13501 ctacggcata catgtggcaa agatcgcagg attgccttcc aatctactag aacgagcagc
    13561 agatatcctg catacgctag aaaatggcga taacggacac catactgttc cagctgaagt
    13621 agaagagaaa actaaaacag ccaaacagga gcaaataaaa ccacctgcag aaaaagtaaa
    13681 tcaagaccat atacaagacc gtgtaaaaga agaaaaccaa cagctttctt tattcagtga
    13741 attatccgaa aatgaaacag aagtcattga atcactgaag caaataaatt tactagaaat
    13801 gacgccaatg gatgcactaa acacattata tgaattacaa aaacaactgt aggaagaagg
    13861 cggatatcga tggccaaaat ccaagaatta tctgaacgtt tagctaatca gatcgctgcg
    13921 ggagaagtag tggagcgacc agcttccgtt gtgaaagaat tagtggaaaa tgcaattgac
    13981 gccggcagta ctcagattga tatcttagtt gaagaagcgg gactgcggac gatccaagtg
    14041 attgataacg gagaaggcat tttggcagac gacgtagaga atgccttcaa gcggcatgcg
    14101 acaagtaaga tccataatcg cgacgatctt tttcgcatac gaacgctggg ctttcgaggg
    14161 gaagctttgc caagtattgc ctctgtttct gaaatgactc tggaaacggc gaatcaggaa
    14221 gaaaaacaag gcacctatct gtcgctgaaa ggcggagaag ttattgagca tcgaccagca
    14281 ccactgcgtc aaggaacgaa gattaccgtc agcaatctgt ttttcaatac gccagcccgc
    14341 ttgaaatacg tgaaaacact gcacacagaa ttagcgaaca tcggggacat cgtcaatcga
    14401 ctggcattga gtcatccatc gattgctttt cgtttagtac atgatggaaa caaaatgctg
    14461 gcaactgctg gaaatggcga tctgaaacaa acaattgcgg gaatctacgg attatctacc
    14521 gcaaaaaaaa tgctgaaaat cgaaggaaaa gatctagatt ttgagttatt tggctatgtt
    14581 tcattgcctg aggtgactcg tgccagtagg aattacttat cgacgatcat caatggacgt
    14641 tttatcaaga acttttcctt gaataaagca atcgttgcag gttatgggtc aaaattaatg
    14701 gtcggtcgtt tccctattgc tgtattggaa atcaaaatgg acccgctttt agtagatgta
    14761 aatgttcatc cgacgaagca ggaagtccgg ctgtcgaagg aaaaagaact aacagagcta
    14821 attagtaacg ccattcaaaa agcattgtct caagaaaatc tgattccaag tgcagcggat
    14881 aatctacggt ttaagaaaaa agtacctgat cagcctaaaa cagaacaaat cgaaatcgat
    14941 ttgtcctacg cttttgaaga agaaaaacct aaaaagccaa gtagtttgaa ttttgatcga
    15001 gagacaggta cctttttcgt agaagaacta aagaacacat ttgttgacag aattgttgat
    15061 aagtctgtgg aaaatgttga aaactattct ggtttttctg aagaaaacac cacttatcca
    15121 gaaaaaacag cgaaaacggt ggataagttt ggtgaaaatg ttgataactt tgtagaaaaa
    15181 acagtggaaa aatctgaaaa gaaagaattt cccattgtgg ataacatgga gaaaacaaat
    15241 gaagaacaag cagataaatc cgtagaagag gatgaaaaga tttacgagga agaattgaca
    15301 ctccatcctg aatttgattt cactcaagga aacgacaaaa cattagaaca agccatcaag
    15361 aaattagaaa cggaaaaacc agtacaacgt tttcctcagt tggaatattt tggacagatg
    15421 cacggaacgt atctttttgc ccaaagtagc gatgggttgt acatcattga tcagcatgct
    15481 gcccaagagc gcattaagta tgaatatttc cgggaaaaaa ttggggaagt atctgatgat
    15541 ctgcaagaat tgcttgttcc atttgtgtta gactatccaa acagtgatgc tttgaaatta
    15601 aaagagcaaa aacacttgct agaagatgca gggatttatt tagaagaatt tggtcaaaac
    15661 agctttattg tacgggccca tcctacttgg tatcccaatg gagaagaaga atcgattatt
    15721 cgggagatga tcgatatgct gctgacaact ggaagtgtga gtgtaaaaaa attccgtgaa
    15781 gcaacagcaa tcatgatgag ttgcaaacga tcgattaaag ccaaccatta tttgaatgaa
    15841 gcacaagcac gtgtgctgct gaaggatctg gcacgatgcg aaaatccttt caattgtccc
    15901 catggccgtc cagtattgat tcactttacc aattcggata tggaaaggat gttcaaacga
    15961 atccaagacc cgcattaagt caaagagaag agggaaaaca tgaagattgt attagcatcc
    16021 caatcaccaa gaagaaaaga gttattggct catatcgttt cagaattcga gattgaacct
    16081 gctgatatcg atgaaacgcc atttccagac gaacagcccg tcgattatgt tcgtagaatg
    16141 gctgaagaaa aagcacgaac tgtctgggaa caagatgaaa aagaagacca tttagtgatt
    16201 gccagtgaca cgactgttgt tctcaatcaa gagatcatgg gtaaaccaga agatctggct
    16261 gaggctgaat tcatgctgaa aaaactaagc ggggaaacac atactgtata tacagctgtt
    16321 gttttaaaaa caaaggaacg agaagaacgg atactagcag aagcacatgt cactttttat
    16381 cctttgacag acgaagagat caaacgctac ttggagacgg gggattatgc ggataaggca
    16441 ggggcatacg gcatccaaaa tgctgcgagt gtattcgtca aagaaatttc tggagattat
    16501 tacagtatcg taggatttcc gattggtgct gtcaatcagg cactgaaaac attcatttaa
    16561 acaaaaaagc ggactatctg attttcgatt gaaaatccat gatagcccgt tttttttatt
    16621 gaaaagatta cttatctact ctgactaaga ttttacttca gctttaccga ctgcttcgcc
    16681 cgggcgaaca agtcctgatt ggtcaagaga aagtcctgca actttttcat tattggtcaa
    16741 agcaacaata atgtcagttt tcttgccagc ttgttctatt tctggcaaat ccatttcagc
    16801 aatcagggtc tctggtgtga caaggtatcc ttctttcacg aatacattga aaggaacacc
    16861 ctttagttca acagtatcta atcccatgtg aacaagtact tccagcccct cattagaaag
    16921 aataccaatg gcatgttttg tttcaaagac actcgtcact ttaccgttta ctggtgcata
    16981 gactttgccg tttgacggtt cgacagcata accgtcaccc atcatttttt gtgagaaaac
    17041 tgggtcattt acttcagtta tttccttgat ggtccctgca gcgactgcga ataatgtttc
    17101 ttttgttgca actgccgtac cagttgctga aacaggttcg aaagactgtg gcgttgctgt
    17161 tgcgccattt gctgtttgaa gttgtacatc agcagcattt tcaggaacag caggatcaat
    17221 cttattcaaa attccctgac gtctaaagat gatcgtcaag ccaaatggaa tgatgacagc
    17281 aatgatcatt gcgatgatga aaggtaccca tgtttctgct tggatagcta gtattcctgg
    17341 caaaccgcct actccgatcg cgttagctcg aacacccatc aagttagcaa acatgccagc
    17401 taatccagag ccgaccattg cagcgacgaa aggatagacg tatttcaaat tgattccgaa
    17461 catagcaggt tcagttacgc ctaagtaaca agaaatcatt gctggaatcg agatttgttc
    17521 ttctttttta ttcccacgat gtaagaagat gatggctaag actgcagagc cttgggcgat
    17581 atttgataaa gcaatcatcg gccataaatt cgttgatccg aaatctgcaa tcagctgcat
    17641 atcgatggca ttggtcatat ggtggagacc agtaatcact aaaggagcat acaggaatcc
    17701 gaatacggca ctaaacaacc agctgataga agacgtcaat ccagtattta cgatatttga
    17761 gatccagctt ccgactgtcc agccgatagg acctaaaata acgtgtgcag ctaaaacagt
    17821 tggtaacaat gaaaacaatg gaacaaaaat catcgagatc gactgaggga tatatttgcg
    17881 gaagaagatt tctagatacg ctaacataaa ccctgccagc atggctggaa taacttgcgc
    17941 ttgataacca atcatctgga cttgagcaaa accaaaatcc caaaatggaa tatctgctgc
    18001 ggctgtggaa gctacactat aagcatttaa taattgcgga gaaactaacg taattcctaa
    18061 aacgattcct aatatttgtg tagtacccat cttttttgca atactccaag tgatacctac
    18121 tggaagaaaa tggaaaattg cttcaccggg taaccacaaa aaggcattga caccattcca
    18181 aaacttcgag tgttcaacga ttgttccacc aagactttca aactggatac cttcaagtac
    18241 atttctgaat ccaaggatca atccaccgac aatgattgca ggaatcagtg gtgtaaagat
    18301 ttctgctaaa acggcaatag cacgttgaac gggatgaagg ttttgttttg cagctgcttt
    18361 tccttgttct ttggaaaccc cttcaactcc agatactgca acgaagtcgt tataaaaagt
    18421 agaaacatcg tttcctatga tgacttggaa ctgtcctgca ttcgtgaaca tcccttttac
    18481 gctaggtata tcttcgatcg ctttttcgtc cgcttttcct ggatcattca ggacaaaacg
    18541 catacgagtc gcacaatgac taactgcagc aatattttct tttccgccga tatcatgtaa
    18601 cagcttctcg gcatctgctt gatattttgc catatcaata aacccctttc tcttaacttg
    18661 tctatgcaag ttgtttcttc atttactata ctttttttcg gagagaattg caagcgtttt
    18721 attaaaaagt acgagagaaa atgatatcgt tttaaaaagc ttaaaataag cttttcttaa
    18781 aaataggaac attgaaatac aaaaagagct gtagtatagt gaagaaatga tggaagaacg
    18841 agtgagggaa aaaacatgaa taagttcaat gaaatttttt tagatttgga acagaaaatt
    18901 ttagcgaaag aatatcctcc gcattcgctt ttacccagtg agaaccaatt gatcaaaatt
    18961 tatggtgttt cacgagaaac aattagaaaa gcgctgaatc ttttgactac ggaaggttat
    19021 attcaaaaaa aacaaggaaa aggttcgatc gtactggatc ggaatcgctt cgactttcct
    19081 atttctggat tgactagcta taaagagcta caggagaccc aacgtattcc aagtgaaacg
    19141 atcatccata cgttagaaga aacagaagtg acaaaagcat tgaacgagat cactggctgg
    19201 gagatcggtg cgcctgtttg gcatttgata cgcgaaagaa aaatcaatgg cgaagtagtt
    19261 atattagaca ccgattatct attaaaggaa atcgttccta ttttaactcc agcacaagca
    19321 caaggatcga tctatgaata ttttgaaaat gagctttctt tgacgattgc ttacgcgcaa
    19381 aaggagatca cagtagaaga agtaacggaa atcatgaaaa cagcgatgga tcttcacgat
    19441 gacacttatg cagtagtagt cagaagcctc gttcatctgg aagatacccg ctgtttcgag
    19501 tattctgagt cggttcaccg attagataaa ttccgtttcg ttgagtttgc ccgacgccga
    19561 aaagtgtaaa tagttcaaaa gaaagcaaat tgttggcatc tgtccacttt ggcgctatga
    19621 taggatcaca aagggggcat ttttaatgga taaaccaata agaccagaaa aagaagaact
    19681 gaaagaaaag ttatcaccca tggcttatgc agtcacacaa gaaaatgcaa cagaacgacc
    19741 atttagcggg aaatatgatg atttttacga aaaggggatc tatgtagata tcgtcagcgg
    19801 tgaaccgtta ttcagctctg cagaaaaata tgatgcaggt tgtggctggc catcattcag
    19861 caaaccaata acgaaaagac aagtgcgcga aaaagccgat ttttctcatg gcatgcatcg
    19921 aatagaagtt cgaagcaaag aagcagattc tcatctcgga catgtgttta ccgatggacc
    19981 agtagatcaa ggtggtctac gttactgcat caattctgcc tcactgaaat tcattccata
    20041 tgaaaagatg gatgaattag gttatgggga attcaaatca cttgtagaat aatggaaata
    20101 cacaaagagc ggtacaatac ggggatttac tcgatcgtcc gctctttttt tattcaagcg
    20161 attgctattt gaaagaaacg ctccctagac tccttttttc acaaggtgaa atgtgctaca
    20221 ataaagggaa cgtatgtgtg caaaagaaag aggactagaa tatgtatgaa tatctgacag
    20281 gtgtggttac ctttatcaac ccctattaca tagtagtaga aaccaatggt atcggctacc
    20341 agatcgcact aggaaatcct taccgctaca gtagcaaact aaatcaaaaa ataaaaattt
    20401 atgtccatca ggtaatacgt gaagatgcgc atcttctgta tggatttgat tcgctagaag
    20461 aaaagcaact gtttttgcga ttagtaagtg tttcaggaat cggtccgaaa agtgcccttg
    20521 caatcatggc aagcgaagac cactccggtt tgattcaagc agtagaatcc agtgatgtca
    20581 cttatttgac gaaatttcca ggagtaggga aaaagacagc acaacaaatg atcttggatc
    20641 taaaaggaaa attcggtgag ctgagtatcg atacaccttt tagtctattt gatgaagcaa
    20701 acacaaaaga cgctacagct ctatctgaag caatggaagc tctctcggct cttggttaca
    20761 gtgatcgaga aatcaaacgt gtagaaaaac aattaaaaga agtagataat cagacaacgg
    20821 atgagtatct acgccaagca ctcaagctaa tgatgaaaaa ataaggagga gaccaaatga
    20881 cagatgaata cttgttatca ccagaatctg gcgaaaatga actgagtttg gaaaaatctc
    20941 ttcgaccaca gctgctttct caatatatcg gacagagaaa agtcaaacaa gaacttcaga
    21001 tttacatcga agctgccaga aatcgggaag aacctttaga tcatgttctg ttgtacgggc
    21061 ctcctggatt aggaaaaacg acgatggcca tggtcattgc taatgagatg accgtaaata
    21121 ttcgtacgac gagtggccct gctatcgaac gtccgggtga cttagtagca atcttgaatg
    21181 aactggaagc aggggatgtc ctgtttatcg atgagatcca tcgattacct agagtggtag
    21241 aagagatgct ttattcagct atggaagatt tctatgtaga tatcatggta ggacaagggc
    21301 caaccgcaca tccggttcat ttccctcttc ctccctttac tttgattggc gcgacgacac
    21361 gggcaggtat gctttctgca cctttacgag atcgatttgg catcatttct catatggaat
    21421 attatgacga acaggatctg caggagatcg ttttacgttc ttcggatatt tttcaaacag
    21481 agatcattga agaaggggca ttggaaattg ctcgccgatc acgaggaacg cctagaatcg
    21541 ctaatcgctt gctcaaacgg gttcgtgatt ttgcgcaagt ccaaggagac gggaaaatcg
    21601 atcgtcctat agcggatcag gcacttactt tgctacaggt cgatcaggct ggattggatt
    21661 atgttgacca gaaattgttg cgaacaatga tcgagttata tggcggcgga ccagtagggt
    21721 taagtacgct ttcagtaaac ataggagaag agcgtgagac ggtagaagat atgtatgaac
    21781 cgtatctgat ccaaaaagga tttttaaagc gtacacctag agggcgaatt gctactgctt
    21841 atgcctatga acattttggt tacgactatc atatatgatt tttgctttta gattggagga
    21901 aaatgaatga gtgatacaac acgtacgaaa caattgatca aaaacgtatt gattgatttg
    21961 tgccaaacgc aatcttttcg aaaaatcagc gtccaaaaaa tcgcaaacga agcaaaaatc
    22021 aatcgacaaa cattttatta tcattttaca gataaatacg atttgcttcg ttgggtctat
    22081 tgtgaggatg cattgcatta tttagatcca caatgtcttt cacttgataa ttgggaagag
    22141 caagcattga aaatgctgaa agcaattgct gagaagaaag aattttatgc aaatactgtg
    22201 ctttctgacc cagaaatttt acaaaaagag ttttctcaac tgatccaaaa atcatttatc
    22261 aagatttttg aacaaatgga tgaagaaaga caactttctg caagagacaa actattttat
    22321 gctcgttttt tttcttacgg ttgcagtggt gtattagtca attggatcac gaatgaatat
    22381 gaagaaacac cgatggaaat cgctatgcag cttttccgtt tagccaagga tacggaatta
    22441 tattcttatc gtctttatgc aaaagaagag ttggaagaac agtaatagaa aaattttttg
    22501 ttggaaaagc aataatcgct aaaaggagat ggggaaatga caaaaatttt atttgtttgt
    22561 ttgggaaata tttgccgttc accgatggca gaaggcttgc tgagaaaacg aatagcatta
    22621 gaaggaaggg aagcagaatt ttttgtggat tctgctgcta caagcacgta tgaagttgga
    22681 aagacaccgc accctggaac gaaaaaaata ttaaaccaag aaaaagtaga tatgacgaat
    22741 atggttgctc ggcaaatcac accccacgat tttgaaactt ttgattggat cattggcatg
    22801 gatcaagaaa atgtagaaga actgaaacga agagcaccac gctcagcgca ggggaaaatc
    22861 catttgtttt taagtagcat tcctggaaaa gaaaaagaaa atgttcccga cccatactat
    22921 accaataact ttgatgagac atatcacttg atcacagaag gcctgaatca ttggtggaat
    22981 atttggattg atgaaaataa aataacaaac aatttgtaaa gttaacgctt tctttttaag
    23041 gcgatgttag agcatttcct tgtttttttg taaaatgtta ggtaaaataa aattaattaa
    23101 gtaacacttt cttagctaaa ggaggagtgc attcgatgaa cgaagagaca gtatcgccaa
    23161 tgaagaagct tacgaagtta gttactcata cttcgtatca actttttgat tcttttgtaa
    23221 atgacactga agaacatgct aagaatgtac gattgcaagg aaagtttatt cttgagctgc
    23281 aaaaagctgc tactgaacat agtctagtta tcttacaagt aagagcaaat cgtttgagta
    23341 gcaagtatga aacgatctca ggctgggtgg cgacaaaaac ggtcgaaaaa gaccgagtga
    23401 tgatccgcct acaaaacgaa gagcagcaga tccggatggt tcctgtagaa caaattgaaa
    23461 aaataacaat cctttcacca gcaggggaac aggaacggtt atcaaaataa tttataccag
    23521 atagaaaagc acgtatgagc ttgtaccatc aatcattact aatcaaaaat aaccgaatgc
    23581 tttaagctga tatcagtaaa acggaacgtt ttaggatgag tatcacagca tgacagcatt
    23641 gggttgatta gttgaatcga ttggatggta caagtttttt tgataaaaaa aggtcctgct
    23701 agccggggag ctagcaggat aaggagttaa aaatgaaaaa gtgttgttag ggttgtttgt
    23761 tggtatgctt atataatagt cactagttgt gaatattttg tgacgaaagt tttcgaaagt
    23821 tgttaagttt ttttgcgaaa actattttta tatcatatat atgtctaaaa tctatattat
    23881 aaaagaaatg ttgtttgatc agcttctctt cggtattagt tcaaaacaaa acggcaaagt
    23941 atatggagct actttgccgt tttgtttctc taatactcag gtcagtttat agacgctcaa
    24001 taaacggtgt tcaaaagcca gtttctcggt attaagtcaa atttatgcaa aaatgtgaga
    24061 agccattttc aaaaaatatt tcttaatact cgaaactgag cggctttttc acgacctctc
    24121 aataaacagt gttcaagaga cagcctatcg gcaataaggc tgaacgtctc tttcacaacc
    24181 tcttttatca atctgctact tcttctttct tagcgaaact ccaaatcagt ccgataacaa
    24241 aaccgataac tgctggtacg atccacccca tccccaattt gaaaaacggc aagtagcttt
    24301 ccgcaacata taaaagattt tgaacaatag gtgtttgttt gatagtttct gggcaagcgt
    24361 tcaacccatc aaaaatcgaa gcaatcaatg taaaataagt agtcattcga taaacagccg
    24421 tacgctgctt aaacaaagga ccaactaaca ctagtaaaat cagtgtcatt gctaatggat
    24481 agatgaacat caaaacaggc aacgaaaatt gaatgatatt cgtcaagcct acgtttgccg
    24541 ctaaacaagg aaggatacta gcaagtgcaa caaagaatgc gtaatttctt tgcggaaaca
    24601 aatctgtgaa tgtttctgca aaagctgtaa tcaaaccaat accggtcttc aagcaagcta
    24661 atataacgat aaatgctaat aagatactgc cataagtacc taaataatga tcagcaatct
    24721 gagccagcgt gatcccgcca ttttcactta gagcaaagct acctaagctc atagcaccta
    24781 aataagcgag caaagtataa atgattccca tcaatataat gctgatcgca ccagatttga
    24841 tcgtgtcttt agcgatttca gcaggttttg ttacacccat gttttggatt gttgtgacaa
    24901 tgatgatccc aaatgctaaa gcagcaagcg catctaatgt gttatatcct tgagtaaacc
    24961 ctgtgaaaaa agcatgctct tgataatttg gctgaatagg cgcttgattt acagaaccta
    25021 gtggattcaa aaaagcaagg agaagcaaag cacctaataa aaccaaaaat gcaggattca
    25081 ggaactttcc aacataatct aatatctttg tcggttttct tgaaaaccac caagccagca
    25141 caaaaaatac aatactgaaa attgctagat atagcgtctg tctgctagga tcgataaatg
    25201 gtgctaaacc aatctcgaaa gatgtggttg caaggcgagg taaagcaaaa aacggtccga
    25261 taactaagta aagcaagatg gtaaaaacca tcgcatatgt ttgatttatc cgttttgcta
    25321 attcatatac acctgagctt ttcgatacac caatggcaat cacccctaag aagggaagac
    25381 cgataccggt aaccaagaaa cctagattcg cccaaaaggt agcagcgcct gcttcttgac
    25441 ccaaatgaac gggaaagata agatttccag caccaaaaaa tagaccgaaa agcatggagc
    25501 ctataaaaag atagtcttta aatgataatt tttttgtcat acataactcc tttacggttt
    25561 ttttaaaagt aacaaaattt cgaaaaatat gcaacaattt tcagaaaatt tcctatataa
    25621 aacgacggtt atttaataac gtaagtgata aaataaaagc gctgaatcat ctgaggagga
    25681 atcatcgtga caaagtcgag attagaagca tttactgatg gagtggtagc cattgttttg
    25741 agagttcttg tattagagat caagatccct aatacatcta gctttcattc tttatgggtc
    25801 atccgaaata cattattagc ttataccatc agctttatat ttgttgcggt gatctgggtg
    25861 aaccatcatc gtatatttca gatggcagaa cgaattaatt accgagtggt ctggtcgaat
    25921 atctttttgc tcttttggct gactttatgt ccttctgtta ctagttgggt cgggcgtaac
    25981 cctgaagctt tttggcctga gatggcttat gtcttagtat acacgatgtg gagtttttct
    26041 tttggtatct tgatgaggca aatcatgaaa gcaaataaac cagattccca tgtcgtgaga
    26101 gttttgtcaa aggaccgtcg aagtcttatc tccatgatga ttaacttatg cttgattgcc
    26161 ggtgtctttt ttgtaccgtt gatcgggtta ttcggacgtt tttttgtatc tggtatttgg
    26221 attttttcct ataaaaaagc agatgcctat tatcagcggt tgtttccggg gaaatagaaa
    26281 agaggctggg acagaagctt ttaactccaa gaaataagcc gaaatttcac aaaaatttaa
    26341 gaagcaattt tcgtaaattc cttcttattt ctcgaagctg accacttctg tcacaactac
    26401 tttcttactt cttacgttca tatttcatat gatagattag taatagaagc aagaaccaca
    26461 caggtgttag taataaagcg attctcgtat cttttcctag gaacaagacg acacacacaa
    26521 aggccatgta aagaaatacc agataattac taaatgggta caacggcatt ttaaatgaat
    26581 gagctttttt gccgaggata cttttacgat atttcatgtg cgtgtagaca agcatactcc
    26641 agataaacaa gaaacaagta gtggcaatac tgcttactag tgtgaatact tcactaggca
    26701 tcacgtaatt caagataaca gaaatgaaaa tgacgatagt agaaaatgtc aaagcattcc
    26761 ctggcacatg atgtgttgtt aactttttga attttttagg ggcactgcct tcttgcgcta
    26821 aagaacgaag catacgtcct gtactatata ttgcactgtt gcaggcagaa gctgctgcac
    26881 ttaatacgac taaattgatc aaggaagcag caatcgtgat cccaatttcc gaaaatactt
    26941 ctacaaatgg actgttatct ggattcaagc tgttccatgg atagattgcc ataatgacaa
    27001 aaagagatcc taagtaaaat aagatgatcc tgataggaat attattgata gcttccggca
    27061 acactttttc aggattttct gtttctccag cgactaatcc aactaattct atcccagcaa
    27121 aagcaaaggt taccatttgg aaagctaaga taaatccttt tgcaccagtt ggaaagaatc
    27181 cgccatgaga ccatagattc gtgatactgg ctgtgccaat atctgtcgta tagtgggtga
    27241 ggatcatata agctcctacg aggataaagg caatgatcgc tacaactttg atcaatgcaa
    27301 accaaaactc taactcacca aacaatgaga cagccaccat attcaagcaa agaagaagac
    27361 ctaatgcaat cagttcagga agccactgag gaacaccagg cgcccagtag cgtacataca
    27421 ttccgatggc tgttaaatcg gccattgcaa tcgataccca gcagaaccaa tacgtccagc
    27481 cagtgatgaa agccgctttt ttgccaagat attctgcaac aaaatccaga aaagaatggt
    27541 tattggtgtt tgataacaga agttcgccta acgcacgcat aatgaaaaaa cagatgcatc
    27601 cagtaataag ataggcgagc aatatcgaag ggccagctag ctggatagac tttccggaac
    27661 ctaaaaacaa ccccgttcca atcgctccgc caatagaaat cagttggaca tgtctatttt
    27721 tcagtccacg ctgcagttct tgctcttcat tcatttttaa atcatcctaa ctaaaaaagt
    27781 ttaattactt ccatattaaa agagttttct gaaaaacaca actaagattc caaaattttc
    27841 agaaatttac cttttatgag taattcataa aaaagaactg cggtaaacac cgcagctctt
    27901 tgtcccaatc agctattgat cctaagcatt taaaatacgt gaaaggaatt cttttgtacg
    27961 ttcttctttc ggatggacaa agatatcttc tggtgtacct tcttctgcaa tcacaccttt
    28021 atccataaaa atgacacggt cagatacatc ttttgcaaat tccatctcat gcgtcacgat
    28081 aagcattgtc aagccagtat gtgctaagtc tttgatcgta ttaagcactt cgccaaccat
    28141 ttcagggtct aacgccgaag taggttcgtc gaatagcaat acatctggat tcattgataa
    28201 tgcccgagca attgcgacac gctgtttctg tccaccagat aattgtgctg gtttggcttc
    28261 gatataacga tccataccaa ctttttccag attttcgatt gctacttttt tggcagtttc
    28321 tttatctcgt ttcaggacag ttgtttgacc agacatacag ttttccaaga cattcatatt
    28381 gttgaacagg ttgaaggatt ggaaaaccat acctagattc gttcgatatt taggtaaatt
    28441 atatttagga gctaatacat tttctccatt ataaatgatc tcgccgcctg ttggtttttc
    28501 cagtaaattg atacagcgca agaaagtaga tttaccagaa ccggaagaac cgatgatcgt
    28561 cacaacttca cctttattga ctgttacgct gatatctttc aatacttcat tttcaccgaa
    28621 gctttttctt agatgtttga tttcaataat tttttcattc atgattcttc ctccttattc
    28681 ctgcaaattt gaattgtcga tttcttcaag cttggtataa gctgaaggac catcgatttt
    28741 cttttctacc gcccgcagga ttctggtgat cgtaaaggtc atgactaagt agatgatccc
    28801 gacgatcgta aatgtttgga agaattggaa attcgcaccg gaagcagagt ttccttggaa
    28861 gaacaaatca gctacgccga ttacacttaa aactgctgta tctttgatat tgataacaaa
    28921 ctcatttcct gttgctggca agatattccg taaaacttgt ggaataacaa cttttctcat
    28981 cgtttggcca tgggtcatac caatggcttg cgcagcttcg aactgccctt catctactgc
    29041 aaaaatcccc ccacgaacga tctctgtcat gtaagctcca gtattgagag agacaataaa
    29101 caaagcggca atcgttcggt tcaatgaaat gccaaaagcg agtgccagac cgtagaagat
    29161 gaccattgct tgtaccatca tcggtgttcc gcggaatact tcgacataga tagaaagaag
    29221 tgcatttccg attttttgga agaagcgagt cagtgcattt cctgattcag gtaccgaacg
    29281 gaagacacca atcagtaatc caagtgtagt accgacaact gtcccgatca atgcgatgaa
    29341 caaggtaagt ccagcacctc gtaagaacat attgccgtat tgtttccaaa tcgtagtgaa
    29401 atcagaaatg atgccaggtt tttcttcact atcagttgca gcaggctgat ctttgactgc
    29461 ttggtccata attttggttc gttcatcgtt agagatgcca gaaagaatct ggtttacttt
    29521 ttggatatcc gggtcgcctt tacgcatacc aacagaaatc tgaacatctt ccgggtttgt
    29581 ctggaagcca tctgcaccgc tgaattcaag catttccaag tctttgttca cactagttgc
    29641 cgttacacct tccggacgtt cgctgacata accatcgatc attccagaag ctaaagctgt
    29701 tctcattgct gagaaattat ccattgcttg ttgtttctgc acatctggta tctgatcgat
    29761 cacagtatag tggaatgtat ttaactgagc agtaatcttt gctccagaaa gatctgctaa
    29821 actttttgct tttgcatatt tgctatcttt ttgaactact actactaatt gtgattcgta
    29881 ataaggatcg gtaaaatcaa tttcttttcg tcgttcagca gtagggctca ttccggcgat
    29941 gatcgcgtcg atcttgcctg attgaagggc aggagccaga ccatcccatt tcgtttggac
    30001 gatgactaat tttttcccta aaccatctgc tactttttta gcgatttgaa catcataacc
    30061 gccggcgtaa ctattttggc cttgaattgg caaggcatta ttctcatctg tttgttgaga
    30121 ccagttgaag ggtgcatacc cagcctccat acctacgcga aactcatcgc tcggtgtttt
    30181 ttcatctgca tttgccagag atcccacact gaatagtgag aagacaaaag caaatagtac
    30241 ggcaactgaa accatatttt ttttcatttt tttctccctt tctgattata tgatacacga
    30301 gcggtctaga tgaaatgcgg taaagcttta tctgaaaaaa taaaaagcga ccgatttata
    30361 gatataaaaa ggccgctaaa attccataag gtgataaacc tctcacaaaa catagcgcaa
    30421 cttagcatca ctgctaagac agtccgcaag ctcttaactt gcgtcccaac atacactcca
    30481 agcaaaaaag tgcacatttc ggcgatcctc cctattcctg cttctccatg tttgcttcac
    30541 tccacagggt taatgattct cgcgacctct acctcattga ttgaggcatc tcgtattcag
    30601 ttatttatac aaaaaaagtt tacgatactc gagaggcttt gtcaatctat aactgctgtt
    30661 ttttgaaaaa atactgataa atatagaaat ctttactttt accgaaaaaa caatcaaaat
    30721 gtgaatcatc tatccattgc aaacgatagt ataattatac acaaaaatgt atgtaataca
    30781 ataaaaaaag aactagaaca gaaaatttcc tgtgtccagt tccatctcga tcatttaagc
    30841 tgccgctttc tttggctcac gtcctaggat cgcttgcaaa agaacaacga cgccataaat
    30901 ggctaatatt agataaatca aacttgagta ttgggtgatt ccccagcccc atgttcgata
    30961 tacggctaat gtaatggcta aaacaattgc ggcaatcacg ttgaataaag caaaagccca
    31021 aagatttcca ttttctttgc gtacaagata aaaaacagag aaataaacgc ttaacgctaa
    31081 ccaggcgata caagccagaa taacgcccca ataaataaag aatggtaaca tatcgattca
    31141 cctcactttt atacagcagt attgtaacac gttttcattc ttttgtcagt gaacattgtg
    31201 ataaattgtt caaatgccca taacactttt ttattcccat ttttctgact tttcaacaat
    31261 aaatttgttc gagtatgggc tataatggaa agtgaggtga caaaacatga aacaattaac
    31321 agtagacgaa gcagcaaaag agatattagc ttatcagcaa attacatttt tgaccggtgc
    31381 aggggtatcc acaccttctg gagtgccaga ctatcgatct ttgtcaggaa tctaccacgg
    31441 gatggagcag ccggaatact tgctgagtca tcaagcaatg gtgaatgaac cggataaatt
    31501 ctatcaattt gtcaaaaaga tttatcatcc tgaagcaaaa cccaatatca ttcatttgga
    31561 aatggcacat ctagcgaaag aaaaaaatgt ttgggttgtt tcccaaaaca tcgacggttt
    31621 gcacgcaaag gctaaaagcc cgcaactcgt caattttcat ggaagtttgt atcaatgtca
    31681 ttgtcgaaaa tgtcaacaaa cggtagactg gaaagaatat cttcacagcg acaaacatca
    31741 agcatgcgga ggacaaatac gcccagacat cgtgttatat ggtgaagggt ttcaagatgg
    31801 agtcatggag caggcggctt atgccgtcag ccaagcagag ctgatcgtca ttgttggaac
    31861 gagttttcaa gttcatccgt tttgtgatct ggtacagttt cgccagccgt cagccaaaat
    31921 cttagtaatc aatcaaacgc ctgtttattt agcggagcct tatacgttta ttcaagaaga
    31981 cggagcggtt gttttcaaaa aaatacaaga attaggagca gattatgact gaattcaaaa
    32041 ccgaaaaaga aaaaatgatt gcaggcgagc tttattttgc caatgatcct gagctggttg
    32101 ccgaccgtat gtttgcaaga agtcaaagcc aaatcatcaa ccaagcagaa tcagcggaac
    32161 tgcgatccca attgttgaaa gagacttttg gccgtacagg gaaaaaaatc tatatggagc
    32221 cagttatcaa ttttgattac ggatataata tatttgttgg ggagaatttt tatgcaaatt
    32281 tcaattgtac atttttagat gtcagcacga ttgaaatcgg tgataactgc atgttcgctc
    32341 cgaatgtcca gctttacacg gcgacgcatc cactacatcc agtgaaacgt aacagcggtc
    32401 tggagtacgc aaaacccatt aaaatcggta ataatgtttg gttaggcgga ggagttatcg
    32461 tcacgccggg tgtcactcta ggggacaacg tagtagtcgg cgcaggttcg gttgtgacca
    32521 aatcttttcc cgacaatgta gtgattgcag gaaatcctgc tcgtatcatc aagacagtag
    32581 aggaagaact aacagaagag tctcttgaaa cattacgtca taagatcgat atgatcgatc
    32641 gagagttgat tgctttatta gaaaaaagaa tggatacggt aactaaaata ggacaagtga
    32701 aaaaagaaga aaaccaagca gtttatgatg caaaaagaga gcagcaagta ttggataaag
    32761 ttgttagtct gctgaaaaat aagggatata aggaaacaat aacagatacg tatgttgatt
    32821 tgatgaaaca ctcgcgcgaa taccaaaaca aaatgaagga ggaataagtg tgatcgaagg
    32881 agagacacgg cgaaaacaaa tcatgcaaac cttggcaaat acagaaaaac cagtgagtgc
    32941 tagcaagttt gcgaaaactt ttggagtcag ccgtcagatc attgtaggcg atattgcttt
    33001 actacgagct gcaggtaaaa gtatcgtggc aacagcaaga ggttatatcc tcgaaacaga
    33061 agaaaccaat actgggcaca tcagtaaaat cgctgtccag catggaaaag atcaaacaga
    33121 agaagaactg agactaatcg ttgaaaatgg tggtgaaatc attgatgtaa ttgtggaaca
    33181 tcccctttac ggtgagttag caggaacttt gcacatcaaa acgccacaag atatcgattc
    33241 ctttatgaga cgttatcaaa aaagtaatgc tactttgtta tccgaattaa caggcggcat
    33301 ccatctgcat acgatccgct acccagaaaa gcatatgctg aaaaacatca aacaaaaact
    33361 agctgaagca ggaatcctct acgaaggata acatcgtagc tgctactttt tatcctagaa
    33421 actattctat catctctgag ataaacaccc atatggaaga aataagaaaa aataagaaaa
    33481 gatgcgtatc caatacacag aattttttgg aattgcgatt tctagatgtc tatctaaatt
    33541 tcgattagtg gagaaacata aaaaagggaa gtgcagcttt tgagcactcc ccttttttat
    33601 aaagctttct tgtagcatag tatcgaagga acctgccaat tctctactcg atcaccaata
    33661 cgccttcttt tagtgcaaat ggattttgat cgttgatgtg gtcatagaac atcacaccgt
    33721 tgatatggtc gatttcatgt tgaacgacga tcgattcata attcttcaaa cgaatcttgt
    33781 gtttttcacc attcatatca taataagaca cagtgatttt ggcatggcga acaacatatc
    33841 ctggtacttc tcgatcaaca gataaacagc cttcaccttc ccctaaacaa gcatcttgaa
    33901 cagaatggct caaaatttta ggattataca taacagtact tagagaaggt ccatctgcct
    33961 ctgggtcagg acttggtacg tgaacagcaa tgattctttt agaaatatct aattgaggag
    34021 cagctaagcc aacaccgcct cgtaagtgta gttcttcagc tttgattgga tcttggctgt
    34081 tttttaagaa ctcaagcatc tcttttccta aagagatatc ttcttcgctt aatggaagag
    34141 aaacttcttt tgcaacttcg cgtaaggtcg gatttccttc acgaatgata tcatccattg
    34201 taatcatgga atatgtaccc ctttcttaaa agactgtgtt tcaagtctat tttcgcatta
    34261 tagtttacca caaaaatgga aaagtagtag taagattgtt tgaaaactac cttttcttaa
    34321 tgattaacta cttgattttc aacccggttt caggtaaagt atagctgtgt gctctaggca
    34381 catgacctgc cacttggtta agcgaatcac caacgtttta ctcagtcgca ggggaataat
    34441 cgaaagaggt gaaagaaatg gcaatttcaa aagaacgcaa gaatgaaatc atcaacgaat
    34501 acgctcgcca tgaaggggat actggttctc cagaagtaca aatcgctgta ttaactgaag
    34561 aaatcaacca cttgaatgaa catgcacgcg tgcacaaaaa agaccatcat tcataccgcg
    34621 gcctaatgaa aaaagttggt caccgccgta acttgttagc ttacttacgt aaaactgacg
    34681 ttcaacgtta ccgcgaattg atcaaacgtt taggcttgcg tcgttaattt tagtcaaaaa
    34741 gagtgggatt cacatgaatc tcactttttt tactcgtata tcaattaagt aaaattccgt
    34801 gatcaagcta gatggactcc tactaaccaa atgaaagctg ctcaaaagac ggctttcggc
    34861 agttttcatt tgtttagtag cgtcttgctt tcacgagaag gaaaaggaga agttatgtca
    34921 gaaaaacaag tattcaaaac gacatggggc ggccgtccct tacaaatcga agtcggtcag
    34981 ctagcaaaac aagcaaacgg agccgtttta gtccgttatg gagatacagt agtcttaagt
    35041 gcagctgtgg cctctaaaga agcaaaagat acagactttt tcccattaac gatcaattat
    35101 gaagaaaaaa tgtatgcagc agggaaaatc cctggaggtt tcatcaaacg agaaggccgt
    35161 ccaagtacgg aagcaacatt gactgcccgt ttgatcgacc gtccaattcg cccgatgttt
    35221 gcagaaggct tccgtaatga agtccaagta acgaacatcg tgatgagtgt agaaacagac
    35281 tgctcgccag ctatggcagc aatgctaggt tcttctttag cactatcaat ctcagatatc
    35341 ccatttgacg gcccaatcgc aggcgtagaa gttggtcgtg taaatggcga gtacgtcttg
    35401 aatccaacag tagaacaagc agaacaaaca gatatcgaat tgactgttgc cggaacgaaa
    35461 caagccatca atatggttga aagcggcgcg aaagaagttt cagaagaaga catgcttggt
    35521 gcattgctgt ttggttttga cgctatcaaa gagttagttg ctttccaaga agaaatcgtt
    35581 caagcagtag ggaaagaaaa aatggaagtg actttactgc aagttgatga agtattgaaa
    35641 aaagaaatct ttgatgcttc ttacgctaca atgaaagcag cagtaatgac tgaagaaaaa
    35701 cttgctcgcg aagataatat cgagcaggtg aagatcgata tccgcgaagc ttatgctgag
    35761 aaatttgcag gtcatgaaga tgaagatcac ttgttgaaag aagttaaaca aatcacagaa
    35821 gatcttgaaa aagatgtcgt acgtgaattg atcaccatcg ataagatccg tcctgacggg
    35881 cgtaaattgg atgaaatccg tccattgtca tcagaggtca gcttattgcc acgtgtacat
    35941 ggatcaggtt tgttcacacg aggacaaaca caagctttat cagcttgtac actcgcacct
    36001 ctaggagagc accaaatcat tgatggttta ggggtggaag tcagcaaacg attcatccac
    36061 cactacaatt tccctcaatt ttctgttggt tctacaggac gtgcaggctc tccagggcgt
    36121 cgggaaatcg gacatggcgc attaggtgaa cgtgcgttag cacaagtaat cccttcagaa
    36181 gaagaatttc cttatacgat ccgtttagta gcagaagtat tggaatcaaa tggttcttct
    36241 tcccaagcaa gtatctgtgc tggcacatta gcattgatgg atgcaggtgt accaatcaaa
    36301 gcgccagtcg ccggtattgc gatgggactt gtttctgatg gtgaaaacta tacgatccta
    36361 actgatatcc aagggctgga agatcatctt ggcgatatgg actttaaagt tgccggtaca
    36421 aaagatggta tcactgcttt acagatggat atcaagattc aaggaatcac agaacaaatc
    36481 ctaactgaag cattaactca agcaaaacaa gcacgtatgg aaatcttaga agaattgact
    36541 tcaacgattg ctgctccacg tgaagaatta agccaatatg caccaaaaat cgaaatgatc
    36601 cagatcgaac ctgctaaaat caaagatgtt atcggtaaag gcggcgatac gatcaacgga
    36661 atcatcgatg aaactggtgt gaaaatcgat atcgatcaag atggaaaagt aagtattgct
    36721 tcagctgatg cagaaatgat caaaaaagct atcaagatca tcgaagattt gaccaaagaa
    36781 gtcaaagttg gtgaagttta tctagggaaa gttgtccgta tcgaaaaatt cggtgcattc
    36841 gtcaacttga tcaaaggaaa agatggactt gtccatattt cccaattagc aaacgatcgt
    36901 gtcaataaag tcgaagatgt tgttaaacta ggtgatgaga tccttgtgaa agtaactgaa
    36961 atcgataaac aaggacgcgt aaatctgtca agaaaagcaa tgttgaacga agatggttca
    37021 acgaaaaatg aagaaaaata atttaattca taggaataat gtacttgtga tcgtgaaggt
    37081 gacaggggga caataattat tcgaaaaaag gggactgtga caaaagccgt gtcacagtcc
    37141 ttttttttcg aataaacggt gttcaaaagc ttgcatctgc ggtaataagt ccagccaagt
    37201 taaaaacatt aggagctgtt tttatttggc tgttcttatt acttgatgca gaacagcttt
    37261 tttacaacct ctccaataaa cgatgttcaa tcagctgtcc ctcgatatta gctcaaaaaa
    37321 cggcaaaata tgaggaacta tttttccgtt tgtttctcta atactcaggt caaaccgctg
    37381 atttcacaac ctctgattca cggtgttcca gaagcagctt ctacggaaat aagctgaaca
    37441 cttttgttac aacttctttt tttctggagt ttcttggcgc atatttttgg agtccttctg
    37501 aataaagcgt aaaataaaag tgagaaatat ggataaagga gggaaaggag atgctgaatt
    37561 ttttatggtc gttatttatc ggcggtatat taggtttgat agctggcgca attttaggaa
    37621 aggaagtccc gggaggcgta tctggaaata tcattatcgg ttttttaggt agttggctcg
    37681 gcgaattttt actaggacca ctgggaccgg aactcggcgg tttttatttg ataccagcat
    37741 tattgggtgc aattttttgc cttgctcttt attcatttgt ggcaagacgt atcagagaac
    37801 gtccaaagaa agaataattt tattcaaata agttgacact tcagtgtgtt acttggataa
    37861 ttagaagcaa tttaggaaag cgggtgtcat ggataagaat atcatctatc attcaagctt
    37921 acctaaagga tatccatata acaagaaatg agggaaaaac gtggcaacaa cgcacaatac
    37981 caaaaagata tcaatgactg gcctgcttgt agcgatggga gtcgtctacg gagacatcgg
    38041 gacaagtccg ctttacgtta tgaaatcgat tgttgaagat aatggcggat tgtcaggaat
    38101 caatcctgat tttgttatcg gatcagtctc attgattttt tggacattga ctctactgac
    38161 aacaatcaaa tatgtcgtga ttgcattgaa tgcagataac catggtgaag gtggaatttt
    38221 ctcactctac acacttgtcc gaaaaggtgg gaaatatttg atcattcctg caatgatcgg
    38281 aggagctgcc ttactagcag atggggtatt gacccctgct gtgacggtaa cgactgcgat
    38341 tgaaggcttg cgaggaattc cgcagttttt tgaccggttc ggtaataacc agaacgtgat
    38401 cgtcattatc actttagtta ttatttttgt tttattcatg gtccaacgct ttggtacaga
    38461 tattgtcgga aaagcattcg gaccaatcat gttcgcttgg tttacttttt taggcgtaat
    38521 gggattaatg aacttcagtc aagactggac agttatccgt gcactgaatc cttattatgc
    38581 tatccagctg ctttttagtg cagataacaa attaggcttg ttcattcttg gaaatatttt
    38641 cctggctacg acaggtgcag aggcgcttta ttccgatctt ggacatgtcg gcaaacgaaa
    38701 tattcgtctg agctggcctt acgtcaaaat ttgtttggtt atcaattatt ttgggcaggc
    38761 tgcgtggttg ttgaatgttt atcaaaaccc tgaagcacag caaatcaaga acctgaatcc
    38821 attcttccaa atgatgcctc aaagttggat cgtgatcggc gttgcttttg caacagtcgc
    38881 tgcagtcatt gcttcgcaag cattgattac aggttcgttt acgctagttt cagaagcaat
    38941 caagttgaaa ctgctgcctc ggttaaagat catgtatcct gggaacagta tcgggcaaat
    39001 gtatatccca gcagtcaatc tgattttatg gatcgcctgt tctctagtgg ttgtcacatt
    39061 ccgaacgtct catcatatgg aagctgctta cggtctatcg atcactgtga cgatgttgat
    39121 gacaacagca ctgctttact tttatcttat ccaaaatggg cattctcgtt ggcttgcata
    39181 tttagttacc tttttcttcg gtgcgataga agtcgttttc tttatctcaa gtgttgtcaa
    39241 attcttccga ggcggttttg tagccgttct gattggtttg atcatcttag tcgtgatgtt
    39301 tatttgggaa caagggaaca ttattcgcga atcgtcaacc gaggatgtgt ctttgagaga
    39361 ttatatcccg cagcttagag aattacgtga tgatacttct ttaccaatct atcagacaaa
    39421 tgtggtcttc ttggttcctg atatggctga agataaagtt ggccgacagt tcatctattc
    39481 gattttagat aaacggccta aaagagcacg agtctattgg tttgttcatg tggaagtgac
    39541 ggatgagcca tatacgaaag aatatcaagt agatatgatg gacactgatt ttattgtcca
    39601 agtgaatctg ttcttaggtt tcagggtcca acaggaaatc aacgtatatg ttcgccaagt
    39661 catccatgat ttgatgaaac aaggccgttt gccaaaacag ccacaaagat actctctgac
    39721 accagggcga gaagttggcg atttccaatt tgtcctgatt gatgaagtag tttccaatgt
    39781 gacaactcta ggaaaatggc aacgtcaaat catgcaggca aaactggcaa tcaaaaaaat
    39841 cgctacctcg ccagaaacat ggtttgggct agagtacagc gaagtaaaac atgaaactgt
    39901 tccgcttatc attggaaata ctcggaaaac atggttgaaa gagcggttgt gaaagtagcg
    39961 ctttgacctg aactaatgtc gaatgtcagc tacttgaaca ccgtttatca gaggtcatga
    40021 aaaagctgta ctgcaacaag cagtaagaac gagcagataa aaacagcttc tcatgttttt
    40081 catctgtttg ggcttaatgc cgtagatgca agcttttgaa taccgttttt atcagaggtc
    40141 atgaaaaagc tgtttagcaa caagtaacgc aatgattttg aagtgataag gagatgtggc
    40201 tgaaaaatgc cgcatctcct tttttattcc taaatatgaa tacgcattat tttcaatctt
    40261 tttgtagaaa aagggtacaa tagaaaaaga gaaaggcggg agaatatggt tatcaatttc
    40321 attattttat ttttgatgat tgcaattact tcattttttg tagcaagtga atttgcttta
    40381 gtgaaaatca gacgatcaag attggaacaa ctagaaaagg aaaatgtaaa gaacgccaag
    40441 ctagctcttc atgttacaca ccatttagat aactatttat cagctagtca attaggaatt
    40501 acgctaaccg gtttgatcat cgggtgggtc ggtgaaggat ctgtcgcggc tttactagaa
    40561 ccagtgatcg gtaaactacc ttttagttcg gctattagca gtacaatctc tgtggcgctg
    40621 ggatttattt tagttacgta tatcgatgtg gttattggcg aactgcttcc taagagctat
    40681 agtatcgtca atacggagaa ggtcgtcttg ttcgtagtta aaccacttca ttatttttat
    40741 aaagtaatgt ttccttttat ttgggtattg aatcattcag ctgcagggct agggaagcta
    40801 ttaggtgtgc gtctcgtatc tgaaggagaa gagacattgt ctcaagaaga gctgacatta
    40861 gtcgcattga attcttatga aaaaggagag ttgaccaaag aagaatatta ttatttggaa
    40921 aacgtgtttg aatttgatga taccttggca aaagatatac aagtagaccg tacgtccatg
    40981 caagtattcg aagcttcaga aaccgtcaaa gaagcgataa aagcttcgat tgaacaagga
    41041 catactcgct atccggttat cttagaatca aaagacaatg ttttaggtta tgtcaccttg
    41101 ccagatttga tcaagcaatc ttataaagat gaccagctga cagtagaaca gttgattgaa
    41161 gagccgatcg taacaactga aacgatccct ataaaaaaat tattgacgat catgcgaaaa
    41221 aagggtaagc atattgctat cttaaaagat gaatacggag ggacaagcgg cttagtgacg
    41281 attgaagata ttttagaaga aatcgtcggg gaaatccgag atgagacaga tttggacgaa
    41341 gcattgatag cggaacagtc agatggctct tatatcatct ccggcaaact aacattagat
    41401 gatttccagc gttattttca tgtagagatt ccagagtttg aagaaacgaa ttttactaca
    41461 cttgcgggct ttgcttctag ccgatataaa gaaataaaag caggaacaat cattgagatt
    41521 gcatcattcc gtttcacggt attagaatac cagcatgcac atatcgatta tttcaaagta
    41581 gagtccacgg aaagaaaaac agaataaaag aaaaaaggct gtgacatttt ttgtcacagc
    41641 ctttttgtta tctaaaaaac ctgttttcgg taaacgaaga agatattttc aataaaagtt
    41701 ttcattttta gccgcaacga tttcttttaa tcaaggctat cttgcttctg catgttctaa
    41761 tgtgaaatgt tcctcttcac ccatgtgttt caattgtttc atcgaacgca tataagagta
    41821 aagcaacacg gcaacagaac cgatccaagc taaaggagaa gctgctgctg ctcctgggta
    41881 tccccacatt cctgtaagaa cgatagctgc aaaagaacgc ataagcaatt ccatcatacc
    41941 ggcgatcgta gggatcttgc tttgtccaag cccttgaagt gtgtagcgta aaatgaacag
    42001 gactgctaag atccagtaaa gagacccatt gatattgaag taggtttgtg ctaattcaaa
    42061 tacacgtgtt tctgatgggt taacaaacaa ttgaacaaag aaatgaccga agaaaatgac
    42121 gatagcacct gctaagagac taaatccgac actcatcagt aaagtttgac gtaccccttg
    42181 caagattcgg ccatattctt tcgcaccata gttttgtgca gtgaaagttg ccattgcaat
    42241 accaaatgac atcatcggct gatttgcaaa ttggtcgata cgaccagcag cggcttgagc
    42301 agctacgaca tctgtcccta gactatttag tgctgcttgt aacacgatag caccaacagc
    42361 gatgatcgaa gattgaaacg ccattggcaa agcagcattt aggtgtacag caaactcttc
    42421 tttttcaaat ttgaaatctt ttttgcgtaa ctgtaacaaa ggcatttttt tcttgatata
    42481 cactagacac agtacgctgg aagaaacttg tgcgattact gtagcaatag ctgcaccttc
    42541 cacacccatg ccaaaataga taataaagat caaatcaagt acgacgttga tgatgaccgc
    42601 aatgatcaga aagaatagtg gtgtgcggct gtcaccaagt gcgcgaatga cattagaaag
    42661 caaattgaaa ctgactgatg caaagatccc taataaaata attgaaataa atgtttgtgc
    42721 ttgatcaagt atttcaggag gagtttgcat caattgaagc atcggacgaa taaacaggag
    42781 acttaggaca gttaaaatca cagtgacgac aagactaatg acaacactag cagcaaaact
    42841 tttcttcaga ccccgataat cttttgcacc gtaacgttgt gcggtaataa tggctaaacc
    42901 agctgttaaa ccttgggcaa agccaatgat caaaaatgtc aggcttccag ttgcaccaac
    42961 cgctgccagc gcatttttac ctagcgtctg acccacgatg atcatatcga tcatattgta
    43021 gaactgctga aaaacatttc cgatcagtaa aggaacagtg aacatcaaaa tcagtttagc
    43081 ggggcttcct tttgttaaat cgcgcatctt ttaaactcct tatatcttta aaatttagtt
    43141 agtagtatat agcgtttatc ctgagaatac caattagaaa tcaatgataa tttatgaaac
    43201 tccataaaaa gaagccaaga attgagtcaa agaatcaaca acttggcctg gtctgtaaaa
    43261 taagggacat ccacgtttat ctatcacctt aatattgtct aatctcactt ggtaaaagga
    43321 tcgtttctct cgtaccgtca tcataggcgt atacttgagc aggaaattgg ttcgaatagg
    43381 caaacggcaa atcaatatcc atttccacat tgcttcctgc ttgagaaaaa tgcatcgtca
    43441 cttttccacg attttcgatc aaatcaaagg ttaatatatt ttctaatgga atgactccct
    43501 taagatctag gtcaataata aaccatatac tgtcaatcaa ttcatctggc aaacttgata
    43561 cgacaccaac tgaagcgtaa cggttgcggc tgctatcaaa actttcaaac atctgtttaa
    43621 cctccttcga atcaacgaat gttttatttt tataattaat cctaggataa actagaaata
    43681 cttacttcaa cgagggttca ttctaataaa gaatcaggaa aaatgcaaca ataattgaat
    43741 actttttttc aaagtataaa tttttataaa ggtacgataa aagtatgcga ggaaaagctt
    43801 ggtaaattag gatttttcgt ttgtaaagcc atttacaaaa gtggaagccc catatgaaaa
    43861 taaacgatta gaaataaaaa aggcgtgtta aaagctgctg acccgccgct tctaacacca
    43921 cctgattgtt tcagtattat tcttctgttg aaccgatcac ttctggttcg ccaccttcac
    43981 ctgtgctttc ttcttcttca ctttgagcga ctacagcagc gatttgctct tcactgtcgg
    44041 tcacgaattt gtaatcgtcg ttttttggaa gatcggctac tgtaatagaa tcacctaatt
    44101 ccaagtttgt cacgtcaact tcaattcgtt caggcaattt gtctggtgta gcagatacga
    44161 ctactgtata caagttttga gctaacactc caccagattt agcacccact gattcgccaa
    44221 caagaacgac ttctgtttcg acttctgttt cttccgacat gtttacagat agaaattctg
    44281 catgttcgaa atgattggta aaagtgttcg tttggatctt gtgaaccaat gtattgactt
    44341 tttgtccatc gatgtccatc gtgatgactg tgttcgctcc atgttcacgc aacaatttgc
    44401 ttagtgtcaa accatcgaat gagatagggg tactttctac tttataccca taaacaacag
    44461 ctggaacttt cccttcgtga cgaagtttgt ttcttaatga acggggacgt acttctcttt
    44521 tacttacttc taatgatact gacataacca aaattcctcc ttaaaatgtg actgtctgct
    44581 ttggtaacgg acagatttta tttaagtgaa ttctaaaggc taatctcgtg cacatcatcg
    44641 aaggcagggc gcttaaaaaa gcgcaaaagg agagatgcgc gcatctcccc ttagaaagtc
    44701 aggattcaac ttttctccac caggtcatta cgctgtgtat gagaaatcca attcacttta
    44761 ctatttaacc gtaacgtgaa ctgttaatta agtcaaggaa taactatgat gatgtatttg
    44821 caagcaagaa tattcaaggt ataattaatt agtagtaata agaaaggaaa cagcatgcgt
    44881 ttagataaat taatagaaga aaaattagaa acgacacgca aggaaatgaa gcggctgttt
    44941 gctttgaagc aagtgatgat agatggcaca gtcgaatttc gacaaaatcg aaatgtagat
    45001 agtttactgc atcaaatcga agtagcaggt gaacacttag aaacaaatga gtcctattat
    45061 cttctcaata aacctgaaaa agctgttaca gctgtatcag atccagaaaa gacgacagta
    45121 atcgatctga ttgcaagtgc cgatcgtttc caaccattat atccagtggg aagactagat
    45181 agagatacaa caggactatt gctgatcact tcgaatggac aattgggata tgaaatgcta
    45241 cttccagaaa aaaaggtttc aaagacttat caagtagttg tgaacgaaag ggtgacaccg
    45301 gcagacgtaa cagcatttga aaatggaatc gtattcgctg atgggtatca atgtaagccg
    45361 gctgatttaa aaatactcaa agcagacaag caccaaagta cggttttatt gacgatccaa
    45421 gaaggaaaat tccatcaagt caaaaagatg ttcttagccc aaggaaagaa agtgaccgca
    45481 ttgaaacggc taagcatggg accattggaa ttagatgaac agctaggagt aggcgagtat
    45541 cgatcgttga cattagcaga gatgaaaaag ttaagtattt attttaaata ggaggtcaaa
    45601 aagatgaaat ataaaacttt attgtttgat gtagatgata cattgttaga ttttcaatta
    45661 actgaagcca atgctttaag tgctttgttt gcagaacaag gaatcacatt gacaccagaa
    45721 atcgaaacca gctataaggc tttgaatcat catttatggc aggagtttga aaaaggcaga
    45781 ctatcacgag aagaaataat aggcagtcgt tttgggttac ttttccagca atttgggaaa
    45841 acagtagata gtgatcaaat ggaaaaacgc taccgccact acttgaacca aggtcatgat
    45901 cttgttccag gaagtctaga aatcctgaaa aaggtccatc cgcatgctga tctttatatt
    45961 gtgacgaacg gtgtgtcgca cacgcaacat cggcgattaa cagatgcagg aatgcttgat
    46021 tacttcaagg atatctttgt ctcagaagct gtcggagcgc aaaagccgat gaaagaattt
    46081 tttgatcatg tcttttccca cattcctaat tttgataaaa agcaaactgt gatcattggt
    46141 gattctttga cttctgatat caaaggagga aatatggcag ggatcgatac gatttggttc
    46201 aatagaaata aattaccaga aatcgaagaa atccagccta cttatcgaat cgattcatta
    46261 gaggaacttt attcattatt ggaaattgaa aaggattaat tttcagaaaa atatagcatt
    46321 ttcgtgtttt ttcgctataa tagattagaa tgaaaaaacg gatacgaaag aggttttagt
    46381 caatgacaaa aagcaagcca attatcattg gtgtgacggg tggatccgga agcggaaaga
    46441 caagtgtcag ccgtgcgatt ttcaacaact tcccggacca ttccatcatg atgcttgaac
    46501 aagattctta ttacaaggat cagagccatt tgagttttga agaacgattg aacacaaatt
    46561 acgatcaccc atttgccttt gataatgatc tgctgattca gcatgtaggc gacttactga
    46621 actataaagc cattgaaaaa cccgtgtatg actatgtagc gcatacaaga agtcaggcaa
    46681 cgatcattca ggaaccaaaa gaagtgatca ttctagaagg aatcctgatt ttagaagacg
    46741 aacgtctgcg tgacttgatg gatatcaaag tatacgtaga tacagatgat gacattcgta
    46801 tcattcgtcg tatcaaacgg gatatggaag aacggggacg cacattggac tccgtgatcg
    46861 aacaatattt gacagttgtt aaaccgatgt atcatcaatt tatcgaacca acgaagcgct
    46921 atgcggatat cattgttcca gaaggcggag aaaaccacgt tgctattgat ttgattacaa
    46981 caaaagtagc tagtttctta aaccataaat agtgcgcagc gaaacagttg aacggactgc
    47041 gaccgtttga aaagcaagga ttctgctttt tgaacagtca ccagccaact gtttttttat
    47101 ttataacaag aggttgtgaa aacagcatct tgacctaagt attaaaaaga agaaacggaa
    47161 aatagctgtt tatattttac cgttttttga gctaataccg aaggtcagct gattgagcac
    47221 cgtgaagtag aggttgtaaa aaagctgtct ttgcatcaag cgataagagc atccaaataa
    47281 aacagctcct cacgtttttc gttgggttgg gcttattatc gtagatgcaa gcttttgaac
    47341 accgtttaac gagaggttgt aacagaagtg gtcagatgca ataaataaga agaaacttac
    47401 gaaaattatt tctcgaattt gtgtgagatt tcgacttatt tttttgaaga agctcttttg
    47461 tcgcaccccc
//
LOCUS       DAXLPC010000011        46219 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.011, whole genome shotgun sequence.
ACCESSION   DAXLPC010000011 DAXLPC010000000
VERSION     DAXLPC010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.011"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            160..840
                     /locus_tag="ACF3UE_000596"
     CDS             160..840
                     /locus_tag="ACF3UE_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFD3634053.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="ACF3UE_000597"
     CDS             930..1964
                     /locus_tag="ACF3UE_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFD3634054.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="ACF3UE_000598"
     CDS             1978..2313
                     /locus_tag="ACF3UE_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634055.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="ACF3UE_000599"
     CDS             2297..4777
                     /locus_tag="ACF3UE_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634056.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="ACF3UE_000600"
     CDS             4833..6392
                     /locus_tag="ACF3UE_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3634057.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="ACF3UE_000601"
     CDS             6389..7753
                     /locus_tag="ACF3UE_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFD3634058.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="ACF3UE_000602"
     CDS             7924..8994
                     /locus_tag="ACF3UE_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3634059.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="ACF3UE_000603"
     CDS             9009..9677
                     /locus_tag="ACF3UE_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634060.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="ACF3UE_000604"
     CDS             9697..10275
                     /locus_tag="ACF3UE_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3634061.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="ACF3UE_000605"
     CDS             10676..11587
                     /locus_tag="ACF3UE_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFD3634062.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /gene="rnhC"
                     /locus_tag="ACF3UE_000606"
     CDS             complement(11965..12882)
                     /gene="rnhC"
                     /locus_tag="ACF3UE_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFD3634063.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="ACF3UE_000607"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="ACF3UE_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFD3634064.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="ACF3UE_000608"
     CDS             13579..14127
                     /locus_tag="ACF3UE_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFD3634065.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="ACF3UE_000609"
     CDS             14242..16602
                     /locus_tag="ACF3UE_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFD3634066.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="ACF3UE_000610"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="ACF3UE_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFD3634067.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="ACF3UE_000611"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="ACF3UE_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFD3634068.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="ACF3UE_000612"
     CDS             19108..20007
                     /locus_tag="ACF3UE_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634069.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="ACF3UE_000613"
     CDS             20000..21262
                     /locus_tag="ACF3UE_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3634070.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="ACF3UE_000614"
     CDS             21423..23321
                     /locus_tag="ACF3UE_000614"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFD3634071.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24370)
                     /locus_tag="ACF3UE_000615"
     CDS             complement(23651..24370)
                     /locus_tag="ACF3UE_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFD3634072.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     misc_feature    24560..24607
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            24707..25039
                     /locus_tag="ACF3UE_000616"
     CDS             24707..25039
                     /locus_tag="ACF3UE_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634073.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25026..27029
                     /locus_tag="ACF3UE_000617"
     CDS             25026..27029
                     /locus_tag="ACF3UE_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFD3634074.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27048..27518
                     /locus_tag="ACF3UE_000618"
     CDS             27048..27518
                     /locus_tag="ACF3UE_000618"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFD3634075.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27539..28123
                     /locus_tag="ACF3UE_000619"
     CDS             27539..28123
                     /locus_tag="ACF3UE_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HFD3634076.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28138..29124
                     /locus_tag="ACF3UE_000620"
     CDS             28138..29124
                     /locus_tag="ACF3UE_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFD3634077.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29114..29425
                     /locus_tag="ACF3UE_000621"
     CDS             29114..29425
                     /locus_tag="ACF3UE_000621"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFD3634078.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29447..31228
                     /locus_tag="ACF3UE_000622"
     CDS             29447..31228
                     /locus_tag="ACF3UE_000622"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFD3634079.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31221..32597
                     /locus_tag="ACF3UE_000623"
     CDS             31221..32597
                     /locus_tag="ACF3UE_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFD3634080.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32604..33239
                     /locus_tag="ACF3UE_000624"
     CDS             32604..33239
                     /locus_tag="ACF3UE_000624"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFD3634081.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33269..34624
                     /locus_tag="ACF3UE_000625"
     CDS             33269..34624
                     /locus_tag="ACF3UE_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFD3634082.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34816..36210)
                     /locus_tag="ACF3UE_000626"
     CDS             complement(34816..36210)
                     /locus_tag="ACF3UE_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFD3634083.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36302..37273
                     /locus_tag="ACF3UE_000627"
     CDS             36302..37273
                     /locus_tag="ACF3UE_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFD3634084.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37270..38052
                     /locus_tag="ACF3UE_000628"
     CDS             37270..38052
                     /locus_tag="ACF3UE_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFD3634085.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38221..38592)
                     /locus_tag="ACF3UE_000629"
     CDS             complement(38221..38592)
                     /locus_tag="ACF3UE_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3634086.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38726..39169
                     /locus_tag="ACF3UE_000630"
     CDS             38726..39169
                     /locus_tag="ACF3UE_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFD3634087.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="ACF3UE_000631"
     CDS             complement(39212..40021)
                     /gene="yidA"
                     /locus_tag="ACF3UE_000631"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFD3634088.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40040..41407)
                     /locus_tag="ACF3UE_000632"
     CDS             complement(40040..41407)
                     /locus_tag="ACF3UE_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD3634089.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41391..42221)
                     /locus_tag="ACF3UE_000633"
     CDS             complement(41391..42221)
                     /locus_tag="ACF3UE_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFD3634090.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42384..42821
                     /locus_tag="ACF3UE_000634"
     CDS             42384..42821
                     /locus_tag="ACF3UE_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFD3634091.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42897..43517
                     /gene="rpoE"
                     /locus_tag="ACF3UE_000635"
     CDS             42897..43517
                     /gene="rpoE"
                     /locus_tag="ACF3UE_000635"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFD3634092.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43706..44212
                     /locus_tag="ACF3UE_000636"
     CDS             43706..44212
                     /locus_tag="ACF3UE_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFD3634093.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            44229..45128
                     /locus_tag="ACF3UE_000637"
     CDS             44229..45128
                     /locus_tag="ACF3UE_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFD3634094.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            45215..46099
                     /locus_tag="ACF3UE_000638"
     CDS             45215..46099
                     /locus_tag="ACF3UE_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFD3634095.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
BASE COUNT        15236 a         7977 c         9766 g        13240 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccagc tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttcgttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgatcga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgactcgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gtttccgtta
    24121 gctttggatg aggatcttcc atgtaaagtt gtggactgac atcttgacca cctgcaagaa
    24181 taagtttgtc gatttgtcca atcagttgag gagctgaatc tggagacatg actggcagaa
    24241 taagaggcaa tccttgagca tctaaaactg catccacgaa tccttgcggt gtatagctca
    24301 cttgatttcc ttggaaagta tctgttgctc gaatcagttg atttccggca atgccgatga
    24361 ttggtttcat ttgtattccc cctaaagtag acttattgta acaaggattt aaaaaaaatt
    24421 aaactatgta agacttgccc ctatacttat ctgttcttgc tgtgttacta tctgtaaaga
    24481 gaaatttcgt gtgaaattca tgacgatagt tgaaaatatt gcttaatttg ttataataaa
    24541 aagtaagcag aaataaaaag gttgggcgta agcttcaagg atctagttct tcaaggggtg
    24601 agaaggacat tttattgaag gggcctgcct atactaagtt atctttagag gtacatactt
    24661 tcaatgaaaa aagaaagcat gtacctcttt tttaaatcga aaggaagtga agcaagtgtt
    24721 agaagctttg gaacaaatcc gaaaagcaga agaagaaaat gaaaagcgtg ctcaaacact
    24781 gcggcagcag ctgaagatct atgcaacaga aaaagagcag gaattggaaa cgatccaaac
    24841 aaactatcga caacaactaa aacagttggt ggaagaaaaa gaacaatttg aaatacaaga
    24901 attagaaaaa gaaaaaatga aattgaaagc agaagcagac aaggtgcaag caactttgaa
    24961 agatcaatat caaaagcatc agagtcaagc gatcggtgcg atcattgaaa gggtgaaaga
    25021 aacttatggc cgtcactaag atggaaaaag tgaccctcat ttcagataaa agaaatcagg
    25081 agaggatttt acaagcagta caaggaatcc aaaacgttga aatccgggat ctgtatcaaa
    25141 atagaacaaa caaccagtgg gtggagaagt attttccaga taccacgatt attgataaag
    25201 aagcaaaatt aagcgcttta ggtaatcggt tgaaagacat ccaagaagct atccaattca
    25261 tacaacacca cggcgatagc cgtcaaaaga aactccattt gaaacgtcaa gaactttcct
    25321 tacaagattt ggaagccaat tattccgaag aaaatttcat aaataaattg aaagaagtcc
    25381 ttgatttaaa agaaaagtgg gaacaactaa ctgaagaacg tgatcgttta gaagaagagg
    25441 aagaatggct tcttcattgg caacagctgg atattgctcc aagtatgtat gcaagtaaga
    25501 cgaccatttt tgagatgggg actgtgagtg cagcaaattt tgaaagtttc aaggaagaac
    25561 tgagtaagct tgatgacgtt tatatggaag aaatagatta tacgccaaaa caagtttatc
    25621 tttcgtatgt tgctttaaaa aaatcagttg ctgttataga agaaattgct gggaaatacg
    25681 ggttcaataa agaaacgtat ccttatgaac aaaatcctaa agaaaaactg caagagacca
    25741 agcagcaatt atccattgtt cacgagcagc aaaagaagat aacgacagcg ttaggtcagt
    25801 gcagtggcta tatccaagaa tttgaatggg tagaagaagt cacacttgcc gttgcagaac
    25861 gagaaaaaat aaaagaacgg tttatccatg cgacttatct gatcgttttg caaggttggg
    25921 tagatgcaga agaaaaacag aatttgctgc atgtgttaaa cgaaaccgta tcagaagaag
    25981 atatatacgt cagtttcgaa acaccaaact cagaagagat tcagcaggaa gtccctacta
    26041 aattgaaaaa ccatccgctt gtcgaacctt ttgaattgct gactgaaatg tacagtctgc
    26101 caaaatatga agaagtagat ccaacacctt ggatgacacc attttatctt gtcttcttcg
    26161 ggatgatggt cgcagatgtt ggttatggtt tgctgatgct cattgggaca atactagctc
    26221 aaaaactact tgttctacca cgcgggatga aacgtttcgt aaaattcttt gagattctct
    26281 cgataccatc gatcatctgg ggattgatct acagttcatt tttcggacag tcattaccaa
    26341 aagaactgtt tggcatccgc ttgcctttcc caatcctatc tacgacggat gacgtcaata
    26401 cgattttgat tttatccgtg attttcggtc tgatacagat tttggttgga ttatttgtgg
    26461 cagcaaagga aaatatcagg agaaaagatt acttgagtgc tgtcagtgat ggatttgcct
    26521 ggcaagggat cctaattggg atcgttattg cgttggttgg tgccatgttg ataaaaaata
    26581 cagcatttgt ttaccttggc gctgggctat cgatcattgc tgccttatgt atcttgatcg
    26641 ttccgattat ccaaacgccg tctaaagtca aaggtgctgc caaaggtgcg tataatcttt
    26701 acggactgac cggctatatc ggtgatttag tcagttatac acgtttgatg gcattgggta
    26761 tttcaggcgg aagtattgga gcggcattca atatgctagt tgctttcatg ccgccagctg
    26821 ctcgattcag tgtagggatc cttttgatca tcgctttaca cgcactgaat atgtttttga
    26881 cactgctaag tgcctatgtc catggcgcac gattgcagta tgtcgaattt tttgggaagt
    26941 tttatacagg aggcggacgt gcctttgatc cgctgaaaac ggcggaaaaa tacgtcaaca
    27001 tcaatcacaa gaaaaaaaac aataaataat tggaggattt ttatataatg atggattact
    27061 taattagtca aaatggtgga atggtatttg cggtattagc gatggcaaca gcgacgattt
    27121 tttcagggat cggttcagct aaaggtgttg gaatgacagg tgaggcagca gcagcattga
    27181 caacaagtca acccgaaaaa ttcgggcagg ctctgattct gcaattgctt ccaggcacgc
    27241 aaggtttgta tggattcgtt attgcctttt tgatttttat caacttagga aatgacatgt
    27301 cagttgtaca aggactgaac tttctaggtg cttctctgcc gattgctttt acaggcttgt
    27361 tttcaggtat tgcccaagga aaagtcgcag cggcaggtat tcaaatttta gcgaaaaaac
    27421 ctgaacatgc tacaaaagga atcatttttg ctgcgatggt tgaaacatac gcgattttag
    27481 gtttcgttat ttccttccta ttagtgttga atgcctaagc ataaaggagg aaaagcagat
    27541 gaacgccatt gaaaaaatca tctctcagat gaacgaagca gcagagcagg aaagagcggc
    27601 gttagaacaa gaagagcgaa tgaagatcga tcaaaacttt gaacaaaaac gtacgcaagt
    27661 tgaaacagaa catcaaaaac aaaaagaaaa acaaatcgaa ttactcgaaa aaaaataccg
    27721 tcagctaagg aatcgccagc aagtagaagt acgacaagaa aatttgaatg cgaagcagga
    27781 atttttaaga cgattgtttg cagatgcggt aactgaaatg gaaaattggg atgaatctga
    27841 acaaatccag tttatcaaaa atgcattgta ttcattacct ttgacaggaa aagtagcatt
    27901 cattgctgga gaaaaatcag cagcctatct ttctcagacg ttgttggatg aatggaacaa
    27961 tgaacttccc tttatgatgg ttttaagtga tgaaactgtt gctgatcaag cgggttttct
    28021 gataaacgat caaggagttc agtataattt tcttttcagc agccttgtac aagatatcca
    28081 aggaacgatg agttttgaga ttgccaatca attattcgaa taaggaggga tcagtgtatg
    28141 gaataccacg aactaaatcc cttgattcgc ggaagagagc ttgaactttt gtccaatgag
    28201 acatttgaac ggatgattca aacaaattct gtcgaagcac ttggtgaaat attgaaatcc
    28261 acgatttaca gtccatatat ttatgacgga tatgaatatg acttcgaaca gaatctttta
    28321 aaggagcaga gccgtctatt tcgctggtta aaggaatcag caccggagcc tgaaatcgtt
    28381 tggatctata cgatgcgtta tactttccat aatctgaagg ttttgacaaa agctgagatg
    28441 acaaatcaaa atctggacca tttgtatatc gacgatggat tttattcatt agaaaccttg
    28501 aaggatgcca ttcatacgca agtttcaaat gaacttcctg aaagcattat ggacagtata
    28561 cgagaagtac gtgattattt tgaagagtct accattcttc agggaattga cgtgatttat
    28621 gatcgacagt ttttgacaga gcagcgacgg cttgccgata agctaggata tcaagaattg
    28681 ctgacagaag tcattgcttt tattgacttg accaatatca caacgatggc tcgaggaata
    28741 ttgcagaaaa gaacatatgg gttcatgacg acggtacttt ccagctcggg aagtatcgaa
    28801 aaagaagtat ttttgaactt tgtagataaa gatatggaag attacacgaa ttttctatta
    28861 gagacagatt atgctgattt tctgcgccct gtcatccgtg agggaaatat tgatctcgta
    28921 aagcttgaac agttgaaaga tgattatcta agttcattgt atcaagaagc acaaacccag
    28981 gctttcggac cactgccact actagccttt ttgaacgcaa aagaggtaga aagcaaaaac
    29041 cttcgtttac tggttatcgg caaaagaagc catttcgaat cagaaacaat cagaaagcgg
    29101 gtgagacaag tctatgacgc ataagatcgg tgtagttggc gacaaagatt ctgttttgcc
    29161 attcaaattg tttggctttg atgttcgtta tggtacaacc aagcaaaccg ttcgtcaggc
    29221 aattgaagaa atggcaaaga atgagtatgg cgtgatttat gtcacagagc aatgtgcagc
    29281 attgagccca gaaacgatcg aacgttacaa ggaacaaatg atacctgcta tcgtattgat
    29341 tcccaatcat caaggatcat tagggatagg gctggaagaa attcaaaaaa acgtagaaaa
    29401 agcagtaggt caaaatatct tatagtatga aaaggagata gaaattttgc aaattggaaa
    29461 aatcataaaa gtctccggac ctcttgtaat ggctgagaac atgtctgatg ccagtatcca
    29521 agacatgtgt ctagtgggag atctaggagt tatcggagaa attatcgaga tgcgtggcga
    29581 tgtggcgtct attcaagtat atgaagagac ttctggaatt ggtccaggcg aaccggttcg
    29641 ctctactggt gaagctttat ctgttgaatt aggaccaggg atcatttcac aaatgtttga
    29701 cggaatccaa cggccattag atacctttat ggaaatcaca caaagtaatt tcttagggcg
    29761 cggagttcaa ttgcccgcat tggaccatga gaaaaaatgg tggttcgaac caacagtaga
    29821 agccggagaa acggtgagtg ctggagatgt tatcgggatc gtagaagaaa caaaagttat
    29881 aaaacataaa atcatggtgc caaatgggat aaaaggaacg atcaaaacaa tcgaaaaagg
    29941 ttcattcact attgatgaaa cagtatgtgt cattgaaacc gaaaatggtg acaaaaattt
    30001 gacgatgctt caaaaatggc cagtaagacg tagtcggcca atcaaagaaa aattaaaccc
    30061 ggatgcaccc atgatcactg gacagcgagt gattgataca ttcttcccag tgacaaaagg
    30121 aggagcagca gctgtacctg gtccttttgg tgcagggaaa acagtcgttc agcatcaaat
    30181 tgcaaaatgg gccgatgtgg acatggttgt ctatgtggga tgtggcgagc gtggaaatga
    30241 gatgacggat gttttaaatg aattccctga attgattgac cctaatacag gagaatcgtt
    30301 gatggaacgt acggtattga ttgctaatac atcaaacatg ccagtagcag ctcgagaagc
    30361 ttctatctat acgggaatca caattgcgga atatttccgt gacatgggtt atgacgttgc
    30421 tatcatggca gactccactt cacgatgggc agaagcactt cgtgagatga gcggacgttt
    30481 ggaagaaatg cctggtgatg aaggttatcc agcttatctt ggttcacggc ttgcggaata
    30541 ctatgaacga tctggaagag tcattgcatt aggatcagaa ggtcgcgaag gaagtataac
    30601 cgcaatcagt gctgtatccc cgtctggagg ggatatttcg gaaccagtca cacaaaatac
    30661 attgcgggtc gtaaaagtat tctggggtct tgattccagt ttagcccaaa aaagacattt
    30721 tccttcgatc gattggatac aaagctattc tctttattca acagaagtag ggaagtatat
    30781 ggatcatatc cttcaagctg actgggcatc catggtcacc gagggcatgc gtattttgca
    30841 ggaagaacag cagctgaatg aaatcgtgcg tttggtaggg attgattccc tttcagataa
    30901 tgaccgtctg acattagaag tggcaaaatc cattcgtgaa gattatttgc agcaaaatgc
    30961 ttttgatgat gtcgatacat tcacttcaag agagaaacaa ttcaaaatgt tgaagatgat
    31021 cttgaccttt ggtgaagaag gacgccgtgc gttgtcgtta ggtgcttatt taagtgagat
    31081 catggacggt accgtatcga ttcgtgaaag gatcggacga agcaaatata tcccggaaac
    31141 agaattagaa aaactagatc aaattattgg tgaaatcaag caaacgatgc aaacgatcgt
    31201 ttcagaagga ggcatgagca atgattaaag aatatcgtac gatcggtgaa gtcgtcggtc
    31261 cattgatggc ggttgaaaaa gttgctggtg tcaaatatga agaattaatc gaagtccgta
    31321 tgcaaaatgg cgagattcgt cgtggacaag tattggaagt ccaagaagat aaagcaatgg
    31381 tccaaatatt cgaaggaaca agtggtatca atttacgtga ctcttctgta cgatttttag
    31441 gccatccttt agaactaggt gtatcggaag acatgatcgg tcgagtattc gatggtttgg
    31501 gacgaccgaa agataacgga ccagagatcc tgcctgaaaa gcatttggat attaacggag
    31561 aagtaatcaa tccagtagct cgggattatc cagatgagtt tatccaaaca ggtatctctg
    31621 caatcgatca tttgaataca ttagttcgtg ggcaaaaatt accagtattt tctggctctg
    31681 gtcttcctca taaagaatta gctgctcaga tcgcgcgaca agcaacggta ctcgattcat
    31741 cagatgattt cgccgtagtc tttgctgcta ttggaatcac ttttgaagaa gctgaatttt
    31801 tcatggaaga ttttcgtcaa acgggcgcaa tcgaccgttc tgtcatgttt atgaatttag
    31861 caaacgaccc tgcaatcgaa cgtatcgcta ctcctcgtat ggctttgact gctgcagaat
    31921 atcttgctta tgaaaaggga atgcatgttt tggttatcat gacagacatg accaactatg
    31981 cagaggcatt gcgagagatt tctgcagcac ggcgagaagt tccaggaaga agaggatatc
    32041 ctgggtatct ttacacgaac ttagctactt tattcgaacg agcaggaaga atccgcggac
    32101 taaaaggatc ggttactcaa attccgattc taacaatgcc agaagacgat aaaactcatc
    32161 caatccctga cttgactggt tatattacag aaggacagat catcttgact agagagcttt
    32221 acaagagtgg gattcagcca ccaattgatg tactcccgtc tctttcgcgg ttaaaagata
    32281 agggaactgg acccggaaag acaagagaag accatgcagc tacgatgaat cagctttttg
    32341 cagcctatgc acaaggaaaa caggcaaaag aattagccgt agttttaggt gaatctgctt
    32401 tatctgatgt agacaagatc tatgcgaagt ttgctgagcg gtttgaaaaa gaatatgtca
    32461 atcaaggatt ctacacgaac cgttcgatta ctgaaacact tgatctaggg tgggaactgc
    32521 tatcgatgtt gccaagaacc gaattaaaac gaatcaaaga cgacatgctg gacaaatatc
    32581 tgccagaagg gaagtgagtt ctgatggcac gattgaatgt gaatccgacc cgcatggaat
    32641 tgactcgatt gaaaaaacag ttgacaactg ccacaagagg gcataaatta ttaaaagata
    32701 agcaagatga actgatgcgt caattcatcc tgttgattcg aaagaacaac cagctgcgtc
    32761 aagaaatgga agagtctatg acagaagcaa tgtctgattt tgtattggca aatgcttcga
    32821 tcacggaacc tttcatcgaa gaattatttg ttttgccggc ggaaaacgtt gatttgtcta
    32881 tcgtagacaa aaatatcatg agtgtaaaag tacctgtgat gaattttgaa tatgatgaac
    32941 agctgacaga cacacctttg gaatacgggt atttgaattc cagtgccgaa ctggatcggt
    33001 caatcgatcg gtttactacc ctgcttccaa aacttttgga actgacagaa atcgaaaaaa
    33061 cttgtcaact gatggcgagt gaaatcgaaa agacacgtcg gcgagtcaat gcattagaat
    33121 atatgacgat ccctcaatta gaagaaacga tctattatat tcgtatgaag ctggaagaaa
    33181 acgagcgcgc agaagtaaca aggttgatca aagtaaaaaa tatgggtacc actgactaag
    33241 tggtatcttt ttttaaaaga ggaaaacgat gattaaacaa agcaaacaaa taaagaaacg
    33301 tttgccggct gttcagcttc tcgcattagg attttttctc ctgattttag ttggcggcgg
    33361 cctacttacc ctaccatttt ttagtaatag tgggcatggg acaaatttta tcgatgcgct
    33421 tttcactgca acttctgctg tctgtgtaac gggattgaca acattgaata cagcagagca
    33481 ttggaacagt gctggtcaat ttttgatcat gcttttgatt gagatcggcg gtcttggttt
    33541 tatgatggtt ccgattctat gctttgcatt gataaagaag aaagtcagtc tcagcacacg
    33601 tattatatta aaagaagcgc tgaatctaga agaagtatca ggtgtgatga agctcatgct
    33661 ttacatccta aaattggcct ttgtgatcca attgattggt acggttgctt tatcttttgt
    33721 atttgtgcct gaatttggct ggttgaaagg tatctggtac agtttgttcc atgcaatctc
    33781 tagtttttgt aatgcagggt ttgatttgtt aggagacagt ttagccaatc accagcaaaa
    33841 tgtttatttg atcatggtgg tatctgcttt gatcatttct ggtgggttag gcttcatcgt
    33901 atggcgtgat ttactggaat atcatcagaa aaagaagatg acgattcatt caaaaatcgc
    33961 attaaccgtt acaggtaccc ttttattagg cggattcgtt gtgttctttt tcacagagcg
    34021 caatggggca acgctagtgg aagggaatat gtttcaacga ttggcaaaca ccttttttat
    34081 gagtgtgaca cctagaacgg ctggatatta ttcagttgat tacctccata tgagccatgc
    34141 aggtctgatt ttaacgatgt ttttgatgta catcggcgga acatctgggt cgacggccgg
    34201 cggattgaaa acaactacgt taggtgtgtt gctgatccag atgcgttcga tgttgaaagg
    34261 acgtacgaga gcggaagcat ttggccgtac catccgacaa ggcgcagtgt tgcgggcact
    34321 tactttattt tttgttacgt tgacgttgtg tgtagtcgcc atcatgattt tatcggtgac
    34381 tgaaacgata cctaaaactt ctggcatcga atatattgct tttgaggtct tctctgcgtt
    34441 tggtacagta ggtcttacga tgggattgac gccagacttg actgcaatag ggaaattgat
    34501 cattatagcg cttatgtaca ttggacgagt tggtgtattg actgtggtct tctctctgat
    34561 gacaaaagca caaagaacac aatcaaaata caaatatcca gaagaaagtg tcatgattgg
    34621 ataatttcat cttctgacag aaacctagtg atttagtaaa ataagaaaat aaaataattt
    34681 ttcttgcttc ttggatactt taagtgcaaa atgttcgttt attttttgag gcactacccg
    34741 ttgttgaacc tcgggtagtg cctctttttt attgaaagga atcaataaga tttgattcct
    34801 ttatttatca ataggttata attcatattt ttttattttt tcttttacga tacttagtcc
    34861 agaagctaaa atttcaaggt tattagagga tagggaaatt cgaacgaatg catctggttg
    34921 cgcacgtgta gtaaagcgtc tggaatgata aagtcggata ccgttagcaa gaaagtcatt
    34981 ctcaattatc ttagggtcaa tctcaggatc aactggaaga attcgatagt aagggacacg
    35041 attcgttggt ttttctactt tgaaaagaga atcaaaaagc tgattggctc tttttgtaag
    35101 acttaattta gtttctaaga tcctatttgc ttcatttgaa tggaggattt gagtgatgac
    35161 ttccacatct aatccagaag ttttcacatt tatattaaaa attgcttgtt ctatcttgct
    35221 ttggacatgt actggaacta caagataagc aactcgcaat ccagaacaaa taaattttgt
    35281 cattccagct aagtagattg tttggttagg taataaattt tggaaaggag gaatgatcgt
    35341 atgttgatag taagttgtta aaaatgaatg gatatcatct tcaataaccc atagaccttc
    35401 tttttcaatc acttcggcta attgctctcg tcttttgtga gagatttgaa accctatagg
    35461 attattacaa gaaggcataa gaaagacacc atgaatcttc ttttttctac attcctgaat
    35521 caatatatca ggtcgcattc cttgctcgtc aaaatcaatt ggaacgatct ctaaatgata
    35581 taactgagcc aattcaatga aattagcgta tgtatatcgg tctgttgcta ttctatcacc
    35641 tggagagaaa agtgcagaaa gtgtgatagc caatccattt tgaacaccgg aaacaataga
    35701 tagagattct aaggacggaa tgactccttg agtttttaac caatttgctg cagtagtcaa
    35761 ttgaaaattt gtgcctttgg gatcttggta attaagcaaa ccaacaagat ttgggttatt
    35821 actagttgat tgaataaacg ggacaacgaa tttattacat tcttcaaaag aactaaccag
    35881 accaaaatca atgatatgtt cggttacttc attggtagag atggtgatgg actcaaagac
    35941 attgggagaa ataaatgtgc cacttccaat attcgtatac agcaaacctt tctcaattcc
    36001 atatttataa gccttgccaa cggtagtaaa atttaaatct aaataatcag ctagctctct
    36061 ttgggagggt aactgagtgt ttttctgtaa tttattcttt aaaatatctt gttctaattg
    36121 ttgaatcaac gatcgataat aaggacgctt caatttttgt ttgtctggtc gccaagttaa
    36181 cgggtaattg tcataagaat taataggcat tttctccact ccttaaaatt gtataccata
    36241 caattttacc attgattgta ttgattttag aagttaatct tttgtgagga gggaattgtc
    36301 tatgaaaatt attaattttg aggaagtagt agcttctttt agttttgaag aagcgattca
    36361 agtaatgaaa aaatgttttt ttgattatga aagtggtaaa atcagccaaa atcctcgatt
    36421 ggtggaaatt ttacctgacg gaaaaggcaa aaatatgttt gcgatgatgc ctgcttattt
    36481 gggggagaac agatattttg gcacaaaagt cattaccgct tttccggata atcatcagta
    36541 tcatttacct tctcatttag gagagatttt cttgtttgat gctcaaaacg gactacccaa
    36601 agcattgata aacgcaaatg cagtcacctg gattcgaaca gctgctgtat ctgcgctggc
    36661 aacagattac ttagcaaatc cgcatgcaga aacacttgct ttaattggag ctggtcaaca
    36721 agcattgtcg catttgactg cgatttctac cattcgtccc atcactacag tgtttgttta
    36781 cgatatttta gaagaaagac gaaatacttt tatcgctaaa gctaaaaaac agtatcctaa
    36841 aataacgttt ataaatgcaa tatcagtaga agatgcagta cgtccagcgg aaatcatttg
    36901 tacgttgacc tctagtaaag aggcatttct tcaaaaagag tgggtaaggg aagacgcaca
    36961 tatcaatgct gtgggcacat ttactcctga tacaagagag ataagtacat cgttgatgga
    37021 aacttctcaa atctatgtag atgattactc agctgcctta acagaaagcg gggacctgct
    37081 tatagccatg gcagaaggag atttagagga atcttgtatt gttggtacat taggcgaatt
    37141 agtttctgag aaaaaaacat tttataaagg agaatcgagg ccgacgattt tcgacgcagt
    37201 tggtctagct attgaagatc tttgttgtgc agaatatatt tataacaaat tagagaaagg
    37261 ggctttaaaa tgaacttaga ttattacgta gttgatgcat ttgcagatga ggtgttcaaa
    37321 ggaaatccag cagcggttta tgtgctagaa gaatggctgc cagaaggtac gatgcaaaaa
    37381 attgccattg aaaacaattt atctgaaaca gcatttacag tgaagaaaaa ccaagaattt
    37441 gagcttagat ggtttacgcc agatcgagaa atcgatcttt gtggtcacgc gacattagca
    37501 acagcatttg ttttatttaa ctattacaaa atacctgatg aaacgattaa attttctact
    37561 caaagcggta atctatttgt gacaagaatt aaagattatt attacatgga ttttcctagt
    37621 attatgccga aaaaagtgcc gatattgtct gaatatgaag aagcgattgg ggctaagatt
    37681 aaagaagcct acttagcacg tgatttattt ttcgtattag aagatgaaaa aacggtggct
    37741 aaattgcagc cagattttac agctatcaaa aattttgaat taggaatagg agtcatcgtg
    37801 acagcagaaa gtgtgcaaaa agactttgtt tctagaacct tctttccaaa attaacaatc
    37861 aatgaagatc cagtatgtgg atcagcacat tctaatctta ttccttattg ggcagaaaga
    37921 atgaataaaa caaaattgtc agcttatcaa atgtcatcaa ggggcgggga tctagaatgt
    37981 gaattaaaag aagatcgtgt gataatagga ggaaaagcag ttttgttttc taaaggtacc
    38041 tcgtttattt gatttctttc aaatgaatta aaaataaatt ggtggagagt ggcaacctta
    38101 tagctacaat ggttgttaaa aaaagacgca aactttttca atttaatgaa aagtttgcgt
    38161 ctcattttaa ttattggtgt ttgtttttta ttcaatcaag agtaaaatgc cccatactaa
    38221 ctatcctcgg atgacttcga ttttataacc atcagggtca atgacaaagt agtaagaagg
    38281 cgcagtgcca ggtaatcctt ttaagtcagt aatctcaaga ccagcagctt tatgttgctc
    38341 gtgtaatttt tctagatcat cagctgctat agcgatatga ccatagccgt ctcctagatc
    38401 atacgcacca tgatcatagt tgtaagtcaa ctctaattca tagtcatccc caggaagtgt
    38461 caaataaaca agtgtaaatt tgttttctgg aaaatcacgg cggcggcttt cttcaaaacc
    38521 aaatgccttt tgataaaatt cgattgatgc ttcaagatct ttcactcgaa cacatgtgtg
    38581 agccattttc atagattcat ctctcctttt ccttttactc aatcataaca aaaagaagta
    38641 aggaaatagt tgatttgtgc ttgttcatga gaaatttctc atgtaaaatg gatagaaaat
    38701 aaaactgtta aggtggaaac tattcatgga taaaccaatt tttggtgaaa aaaagcaatt
    38761 tgctgattat caaacccgtt atgcagcata tattgtcata gaaagagatc agcagattgc
    38821 agtaatcgag gctccaaatg gtgctttttt tcttcctggc ggggaaattg aaggagaaga
    38881 gacgaaagaa gaagcgattg tccgtgagct gatagaagaa atgggaattg tggcagaaat
    38941 ttcttcttat ctgggagaag ctgatgagta tttttactcg aattatcgtg caacttatta
    39001 ttataatcca ggatatttct ttgttgctga ttcttggaag cgtataggag aaccaactga
    39061 aaagaccaat aaaatttggt gggtgagccc tcaagaagcg cttgtgaaat tgaaacgtgg
    39121 tagccaccga tgggcagtcg agagatggat cgaaaaaaat aaaaactgaa agaaagcgag
    39181 tagatcagct ttctctcagt ttttttattt attacagtac atattttttg attgcttcag
    39241 ctacaccgtg ctcgtcgttt gatgaagtga tgacatttgc tgcttctttg acaagagaaa
    39301 cggcatttcc cattgctact cctagaccag catattcaat catggataag tcgttctcgt
    39361 tatctccgat agccatgatt tcatcttgat caataccaag gtgctgtgcg agattcgcaa
    39421 ctgccgcacc tttacttgct tctttattta gtacttcgaa gtaatagggc gcacttttga
    39481 ccgttgtgta tttatcacgg aaagtttgcg gtaaacgcgc aattgctgca tctaaaattt
    39541 ctggttcgtc gatcatcatc attttgacga tgttcatgtc tggtgtcatt tcttcaggtg
    39601 ttcgatattt tagcggcatc ttgactaaac ttgcttcgtg gatcgtataa gcgctgatat
    39661 ctcgattagg cgtgtagatc gctttgtcat cgatcgaatg gagatgactg ccgacacggc
    39721 gtgccattac ttcgatctct aggaaatctt catgtgtcag tccgtgacgg gcgatgattt
    39781 tacctgattt cgtttgttgt acgagtgccc cgttataagt aataacgtaa tcattatctt
    39841 gaaaaaggtt caactcgttt aactgttcct ggacacctgg taagggacgg ccagtgcata
    39901 aaacgatcga aacacctttt gcaacagcag cggcaatcgc ttcttttact tcttttgtta
    39961 cttctctttt ctcatttaat aaagtaccat cgatgtcgat agcgactagt ttgatagaca
    40021 taatttcctc caatatattt taatttattt caatcaatgc gccattacgg atatggctgg
    40081 caaattcttg ataagtttcg tcaaataaat cataatgatc acgcaaggac ggatcaacca
    40141 tttcttttgg aaagaaaaat cgctcatctc cttgttcttg tcccgctaat gcagcaacaa
    40201 gctgactaac ctgtgataat tctatcaaag ttccgtcatt tcgcaaaatc tcgatttgtg
    40261 tgcgatgtct gccttgttct gggcgataaa aatcataagg tagatcgtag ctagaattca
    40321 cagcagtgta ataaacagga ttatatccga ccttttctac taacaaagtg agttcttgga
    40381 ctaattttga atcccggttg ccagaaaaag tagcagattt cagtggttta cgattcaaaa
    40441 aacgtttagc taaatcattt aaaataggat cagcagattc agaccattga gtaaagtaag
    40501 tgcccaagac cccatcatca agtttgaggt attcttctaa agtaaagctt ccgtcaagaa
    40561 atggcagaag taattgagaa tggagttcaa aactgctggc atcttcttga tacaactcgt
    40621 gtgcgcgatg aagcagatgc tccaaaatta cttccatacc acgggaaaca ggatggaagt
    40681 acacttgcac atacatttga tatcggctaa cgatataatc ttccactgca tgcatgccac
    40741 tcatggaaaa agcgatcccg ccttcataag gacgaatcac acgtaatatt cgggtaagat
    40801 caaatgttcc atattctgtt ccagtgaaat aagcatcccg aagcaaatag tccattcgat
    40861 ctgcatcgat ctgactagaa atcatttgga caacttgtgg gttggggtaa gttttttgga
    40921 tcacactagc taccttttca ggaaaacctt cttctactcg gttaagaatc tgatacactt
    40981 ctgtttctgg agaagtgatg atctctacag tgatggcttc atgattcgta tggaagatat
    41041 gttcaaatgt atgagagtaa ggaccatgac cgacatcatg caacagtgcc gcacataaag
    41101 tcaccagccg ttcctgatca tcccagcctc cgttgcctat tttttctttt gaaaaatttc
    41161 gagaaaagat atcgcagatt cgtcttgaaa tctcataaac gcctaatgaa tgagtaaaac
    41221 ggctatgttc tgctccgtga aaagtgaaag aagaagtgcc taattgttta atgcgtcgta
    41281 gacgttggac ttctttcgaa ttgatcaaat ctaagattac ttgatgctgg acatggatat
    41341 agttatggac tggatcacga aaaacttttt ccataggcag catttgatat ttataagggg
    41401 ttgtcataat gtagctcctt tatgttatta cgttgttcca ttctctggat ttggttgttc
    41461 cattgctcca gctggatttc tttttttagc cagtcggtag aatcctgtaa atcacttgca
    41521 gaatacagct tttcaaaagc ttttgcaaat gcttctttga cttcttttac aaaaaggggt
    41581 tggtcaagca gttcttcaag tgttgccatt gtagcaggat ccactgcagg atagccattt
    41641 gtaccaaagt cttcttttaa agcagattga taaaatcgct tcatgacttg cccacgtttt
    41701 tcctgattac cgttgacact taagtacatc ataacagaaa tcccattttt gatccgacgc
    41761 tgagcgatac cggcaaattt tttgccatgg atgcttaaat cataagttcc aggacaataa
    41821 gaatgggtga tttcgaatgc ttgtatcggt gcctttggaa aagcgtattt agtcaatagg
    41881 agcatttgct cgtaagcgtc atctatggtt attttttttg tgtcactttg ggggaaaatc
    41941 aaagaaatat tcaaaattcc ttcatctgat acgatcccta atccacctga atttctgatc
    42001 actggagcgt aacctgcatc ttccagtgtt tggatcccgt cacttagaaa aggagttcga
    42061 acatccttca tacctaagat gactgtgcag tcatattgcc agaaatgtaa aaagatttgc
    42121 tggtgttctt tagaatattc cgttaatata tctgttaatg caaaagggga aaagtcgttt
    42181 ttttgataaa tgtgctgatc tagtcgaatc gcagggttca ttcaaccggc tcctttgtat
    42241 aaattcatat tttctacaat attatactct aaaatcaaag agttgttttg gaaaaaaggt
    42301 tttctgtaaa aatggacaag ttggttgaca aaacaaaaga aactaggaac aatgtagcta
    42361 tgagaagtaa aggagaatga ataatggaat tatcacaagg aacaccgatt tcaatcaaat
    42421 tgcgtacaaa agtaaaacag caaggggaag tgcaagattt ttattttgat ttgaaagggc
    42481 aaatggtgac aattggcgat acgctgtaca tacgttataa agagattcag gaggagacgg
    42541 gcgatgagat tcctgtaacg atcaaattag ttccagatgg tcatgtacag ctgatccgtg
    42601 caggagaaat gcggatgcgt ttgaaatttg gctataaaga acggttagaa acatcctatc
    42661 gaacaccata cggtatgatc cagattgcta cttttacgaa agaactgcat gttagtttga
    42721 aagaccgtcc cacagcaggg aaggttcgaa tcgattatga tctgttcatg ggaccggaaa
    42781 aaatcggcga atattatttg accttggatt ttacagcgta aatataaaag aaaagtttga
    42841 ttttttgtgt ctgattttgt atgataagga gtagactgtg aaaggacgtg tcctgattgg
    42901 aaattagtgt atttgaaggt gcaaacaaaa gcgaattatc aatgatcgaa gtagcacacg
    42961 cgatcttaga acaacgtggc gatgtcatgg atttttctga tttagctaac cagatccaaa
    43021 actatcttgg gaaatcagac agtgaaattc gtgattcact cgcacaattt tatactgact
    43081 tgaatattga cggcagcttt atctcattag gggataatcg ttggggcttg cgttcatggt
    43141 atgctatcga ttcgatcgat gaagaagtaa accatggaat ggacgaagag gatgaagata
    43201 ctccacgtcg ccgtaaacgc aagaaagtca acgcctttat caatgatgat gaagacgcga
    43261 tcgattacaa tgacgatgac ccagaagata cagatctgac agaagaagat gacgatgatc
    43321 tgtttgatga cgatgatgat gaagatgaag aaatcgctgc ttataattct gacttgcaag
    43381 aaatcggagc agatgacccg acagatgatg aagaagactt gccaggaaat atcgaagaag
    43441 atttaagtat catagacgaa gacgatgatg atgaagatta tgaagaggaa gaattttctg
    43501 actctgaaaa agaataaaca ttattttctt acgagaggtt gtgacagaga cgatcagcct
    43561 atcagaataa ggaggtgtga cacgattttt gtcacacctt cttttttgta tataaaaatc
    43621 ccaagtaaat acataaaaaa taaaaaaatt gaaactttta gcgcaccttg tacgtcatat
    43681 taagtgaggc agaaaggagt ggagaatgat ttttactgga tataagaaaa aacggcagat
    43741 cgaaaaatac cgtcacctgc tgaatggact catcgaaact gattatcaaa aaatgttccg
    43801 tatcacgatg aattacgtac atgataaaga agaggcctta gatgtgatgc aagatagttt
    43861 tcataaagcc ctgaactatt ttgaaaaaga aaaagagatc gagcatttta gtgcatggtt
    43921 ttatcggata ttgatccgca cggcattaga tagttggcgc agacaaaaaa ggacgcctgt
    43981 ggacttattt gaaattcaag atatccccca acagttacct ttagaaactt ccgttgcaga
    44041 gctccatatg attttagata aaatagacag tccggaaaaa gagattctga tcctctactt
    44101 ttttgaagga tttcgtttga aagaaattgc gactatcttg gatatgaatg aaaacacagt
    44161 taaaacgaaa atgtaccgct cattgaatgc tttacgtcaa atcctagaat gaaggagaga
    44221 agagtgccat gtattcccaa aaagaaaatt taaaaaaact aaagaaaact tataaagaac
    44281 aagcaattcc caaagggctt aaagaggaga tccgccagcg ttttattatc gaagagcaat
    44341 catttataaa agcaaagcgg agaaagagac gtctccaagg gttcggagta tctttggcta
    44401 tcgtaatgat tacaacaagt agccttcttt ttaatagtca agttcgaagc tttgcagaag
    44461 atttacccat cttaggatca gtcattgaat tgatcttagg cgaacgcttt actgatcgat
    44521 ctgaaaaaat cgatattcag gtaccgaaga tcaatacaca aaatgagaaa gaaaataaaa
    44581 caattcatgg attaaatcaa aaatactttc gcgaaggaca agcagatttt gaaaaagctg
    44641 aaaaagaata tggaaatttt gaaacggatc attaccaagt tttgggagat tatcagaaaa
    44701 tcgtagacga taaccggttt ctcgtgattg aaaggcagat cacccaaaca gcagcagata
    44761 gccatgttga aaaaagatac gacacaatcg acaagaaaaa cagtgtccag ctctcacttc
    44821 cacttttatt caaagatgac acctatctat ctgttttgac aaaagaagtc aaacggcaga
    44881 tggccgaaca agtcaaggaa gatccatcta agtactattg gactgagcaa gatattcaag
    44941 aagggacgat agaaaaacca acacttgtta cgcctacacg aagtttttat ttgaacaaag
    45001 agcatcaatt agttttgact ttttctcaat acgaaattgc tcctggttat atgggtacac
    45061 cagaatttgt cattcctaag tccgtgacaa aaacgatttt ggcatcggaa gattatttgg
    45121 atcattagac gagaagtagt tgcgactagc agtttcaatt ttcaagtaag tacaagtaaa
    45181 taataagaag agaaaaagag aaagaagaga tatagtgaaa agaaattatt tagttatcag
    45241 tattattgct ttatccgtgc ttttgttttt cgaaattact tcggtggcct ccttgatcac
    45301 cgaagtaaaa ggacaaacac actcttcgga gcattcgtca caatctttca aacaatcaga
    45361 acaatcaacc attaaaagcc aatcaactga aacagctaac gtcaaagaag ccattcaaga
    45421 atcagcggaa aaggtacaaa gtcagtcatc acaatcaaca caagacagta caaaaacgag
    45481 ccgagatccg gctgtcaaaa gcgtcgcaat cagctttgat gatggaccag gagcgaccac
    45541 aacaccgcag cttctgcgaa tcttaaaaga aaaaaacgtg catgccactt ttttcgtctt
    45601 aggagaaaat acggcgcagc atcctgaaat cgtgaagcag acagctgaag cagggcacga
    45661 gattggcaat cacacatacg atcatcagaa tctggccact ctttctgccc agtcgatgac
    45721 ggaggaagtg acgaaagcag acactgagat caaaaaagtc actggcaaaa cccccacttt
    45781 tgttcgtccg ccctatggtt ctgtcacgaa tgtaggagca acgatcatcc agcgaccgat
    45841 catcgaatgg tctgttgatt cagaagattg gaagacaaga aatcctgatt tgattttgca
    45901 gaagatccaa gcaacagtat acgatggggc aattatttta ttccatgata tctatcctga
    45961 aacgattcgt gccgttcctc aagtgatcga ttatctgaaa gagcaagggt atcgcatcac
    46021 gacagttggg gatttattag ggcatccaac ggctgtcgag aactattatg gcagaaacga
    46081 tcatcggcca gttcagtaag tgagacaagt atctttaata aataacacat tttaataagt
    46141 agttgaacac ataactacct tacttgcaaa ggcttaacaa tatctataca ggtacaacaa
    46201 aaaactgtcc accaatttt
//
LOCUS       DAXLPC010000012        43826 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.012, whole genome shotgun sequence.
ACCESSION   DAXLPC010000012 DAXLPC010000000
VERSION     DAXLPC010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43826
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.012"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(465..2846)
                     /locus_tag="ACF3UE_000639"
     CDS             complement(465..2846)
                     /locus_tag="ACF3UE_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFD3634096.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2836..3483)
                     /gene="recU"
                     /locus_tag="ACF3UE_000640"
     CDS             complement(2836..3483)
                     /gene="recU"
                     /locus_tag="ACF3UE_000640"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFD3634097.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3547..4086
                     /locus_tag="ACF3UE_000641"
     CDS             3547..4086
                     /locus_tag="ACF3UE_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFD3634098.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            4176..4595
                     /gene="gpsB"
                     /locus_tag="ACF3UE_000642"
     CDS             4176..4595
                     /gene="gpsB"
                     /locus_tag="ACF3UE_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFD3634099.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4617..4984
                     /gene="rnpB"
                     /locus_tag="ACF3UE_000643"
     ncRNA           4617..4984
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACF3UE_000643"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            5193..6359
                     /locus_tag="ACF3UE_000644"
     CDS             5193..6359
                     /locus_tag="ACF3UE_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFD3634100.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6405..7901
                     /locus_tag="ACF3UE_000645"
     CDS             6405..7901
                     /locus_tag="ACF3UE_000645"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFD3634101.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYGIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     LLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            7982..8665
                     /locus_tag="ACF3UE_000646"
     CDS             7982..8665
                     /locus_tag="ACF3UE_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD3634102.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            9310..10500
                     /locus_tag="ACF3UE_000647"
     CDS             9310..10500
                     /locus_tag="ACF3UE_000647"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFD3634103.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            10602..11555
                     /locus_tag="ACF3UE_000648"
     CDS             10602..11555
                     /locus_tag="ACF3UE_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFD3634104.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            11624..12973
                     /locus_tag="ACF3UE_000649"
     CDS             11624..12973
                     /locus_tag="ACF3UE_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD3634105.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(13156..13479)
                     /locus_tag="ACF3UE_000650"
     CDS             complement(13156..13479)
                     /locus_tag="ACF3UE_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634106.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            13608..14771
                     /locus_tag="ACF3UE_000651"
     CDS             13608..14771
                     /locus_tag="ACF3UE_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFD3634107.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            14841..16190
                     /locus_tag="ACF3UE_000652"
     CDS             14841..16190
                     /locus_tag="ACF3UE_000652"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFD3634108.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(16235..16666)
                     /locus_tag="ACF3UE_000653"
     CDS             complement(16235..16666)
                     /locus_tag="ACF3UE_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3634109.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            17054..19696
                     /gene="alaS"
                     /locus_tag="ACF3UE_000654"
     CDS             17054..19696
                     /gene="alaS"
                     /locus_tag="ACF3UE_000654"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFD3634110.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            19896..20492
                     /locus_tag="ACF3UE_000655"
     CDS             19896..20492
                     /locus_tag="ACF3UE_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD3634111.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            20614..21762
                     /locus_tag="ACF3UE_000656"
     CDS             20614..21762
                     /locus_tag="ACF3UE_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFD3634112.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(21800..22213)
                     /locus_tag="ACF3UE_000657"
     CDS             complement(21800..22213)
                     /locus_tag="ACF3UE_000657"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFD3634113.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            22292..22723
                     /locus_tag="ACF3UE_000658"
     CDS             22292..22723
                     /locus_tag="ACF3UE_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFD3634114.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(22822..23055)
                     /locus_tag="ACF3UE_000659"
     CDS             complement(22822..23055)
                     /locus_tag="ACF3UE_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3634115.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            23238..24908
                     /locus_tag="ACF3UE_000660"
     CDS             23238..24908
                     /locus_tag="ACF3UE_000660"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFD3634116.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            25055..25441
                     /locus_tag="ACF3UE_000661"
     CDS             25055..25441
                     /locus_tag="ACF3UE_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634117.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            25428..26126
                     /locus_tag="ACF3UE_000662"
     CDS             25428..26126
                     /locus_tag="ACF3UE_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFD3634118.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            26131..26595
                     /gene="lspA"
                     /locus_tag="ACF3UE_000663"
     CDS             26131..26595
                     /gene="lspA"
                     /locus_tag="ACF3UE_000663"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFD3634119.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            26592..27503
                     /locus_tag="ACF3UE_000664"
     CDS             26592..27503
                     /locus_tag="ACF3UE_000664"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFD3634120.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            27738..28277
                     /gene="pyrR"
                     /locus_tag="ACF3UE_000665"
     CDS             27738..28277
                     /gene="pyrR"
                     /locus_tag="ACF3UE_000665"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFD3634121.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            28291..29574
                     /locus_tag="ACF3UE_000666"
     CDS             28291..29574
                     /locus_tag="ACF3UE_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFD3634122.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            29587..30513
                     /locus_tag="ACF3UE_000667"
     CDS             29587..30513
                     /locus_tag="ACF3UE_000667"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFD3634123.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            30532..31812
                     /locus_tag="ACF3UE_000668"
     CDS             30532..31812
                     /locus_tag="ACF3UE_000668"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFD3634124.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            31817..32893
                     /locus_tag="ACF3UE_000669"
     CDS             31817..32893
                     /locus_tag="ACF3UE_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFD3634125.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            32898..36083
                     /gene="carB"
                     /locus_tag="ACF3UE_000670"
     CDS             32898..36083
                     /gene="carB"
                     /locus_tag="ACF3UE_000670"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFD3634126.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            36137..36913
                     /locus_tag="ACF3UE_000671"
     CDS             36137..36913
                     /locus_tag="ACF3UE_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFD3634127.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            36910..37842
                     /locus_tag="ACF3UE_000672"
     CDS             36910..37842
                     /locus_tag="ACF3UE_000672"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFD3634128.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            37839..38555
                     /gene="pyrF"
                     /locus_tag="ACF3UE_000673"
     CDS             37839..38555
                     /gene="pyrF"
                     /locus_tag="ACF3UE_000673"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFD3634129.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            38562..39191
                     /gene="pyrE"
                     /locus_tag="ACF3UE_000674"
     CDS             38562..39191
                     /gene="pyrE"
                     /locus_tag="ACF3UE_000674"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFD3634130.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            39179..39493
                     /locus_tag="ACF3UE_000675"
     CDS             39179..39493
                     /locus_tag="ACF3UE_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634131.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            39531..40172
                     /locus_tag="ACF3UE_000676"
     CDS             39531..40172
                     /locus_tag="ACF3UE_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFD3634132.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            40215..40907
                     /locus_tag="ACF3UE_000677"
     CDS             40215..40907
                     /locus_tag="ACF3UE_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFD3634133.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            40904..41806
                     /locus_tag="ACF3UE_000678"
     CDS             40904..41806
                     /locus_tag="ACF3UE_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3634134.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(41964..43670)
                     /gene="efbA"
                     /locus_tag="ACF3UE_000679"
     CDS             complement(41964..43670)
                     /gene="efbA"
                     /locus_tag="ACF3UE_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFD3634135.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        14056 a         7710 c         9506 g        12554 t
ORIGIN      
        1 taaagtaaat ttatttaata ataaacaaaa tttttcagct tttttattct tggaataacg
       61 aggtattgtt ttcgataaaa aaagatggtg cagacaaatt atgataatta agcatactat
      121 cagataactc aaaatgaagc cttctttcaa aaaattattc aaaaccatat attgtatttt
      181 ttatttgata ataacaatgg gattattaag aagtggcact aaataaaaga ctagtgtgta
      241 tttagccgat ttaattataa acaagtaaat ggataaagta tatgtaatga taaaagaaaa
      301 atggattttc taatttttaa gctaaatgtt agatcacaca tgtatatgct ggatagtctt
      361 ataaaaaatc atgtaataca gcttggtaca tgatttttat ttgtagctgt tttttacata
      421 gacacaaaaa agaaaccacg cttgtagacg tggtttcttt tttactatct gtttccagaa
      481 gctgaggtgc tgctggatgg tgtatggtca tttgcagcat ccgctccgct agttgctggc
      541 tcactggaag aagcaggagg agcagatgaa gacggtgtcg agctttcttc ggatgaagaa
      601 gaaggaaccg ttgttgaaga cgctggctcg cttgtttctg ctgtcgtgct ttcttttgag
      661 gactcagcag ttgattcgct ttgactagta gagctagagc tttgagtcgt tgtctctgtt
      721 gttgagcttc caggagtctg gacatagctg gaagatggaa tagttgttga tggtgtaatt
      781 gcattcgatc tagctgtata ttgatctttg tagtacagtt caccgcccac acgaattaat
      841 ccgcttggca tctcccagtc tgtatttgtc acgttagctg aaacatactg cataagctcg
      901 cgataaacat cagaggctac gtgtgacgat tctgaagtga caggtgtcat ttttttattg
      961 taacctgtcc acacggaaat cgaataattt ggcgtatagc ccgcaaatag gatatctgga
     1021 tacaccccag aagaaatacc aagttttgca tactcgtcat ctgtgtaatt ggatgttccg
     1081 gtcttaccgg cttgatataa cccagcgatt tgcgcattcg taccagttcc ttcagtgatc
     1141 gtatctttta aaatgtctgt gatcatataa gctgtttctg gagacatggc tgtttttcca
     1201 tctggctcat aagtttcttc tgttccgtct tggaagacga ttttattaac atattgaggt
     1261 ttgtaataag tccctccatt ggcgaaagcc gcataggctg ctgccatttt taaggaagaa
     1321 gctccgtatt ttgtcccatc ttgttcttcc gtattactag agatcgcatt cgattgatgg
     1381 atcgtactgt attcgatccc aagatttttt aagaaagaag ccactttatc tgaaccgact
     1441 tcattgaata atttgactgc tggaacatta cgggataagt aaagtgcttg gcgtaaagta
     1501 atggtgccca tatattgatt atcccagttt cctacaggag tcgaagtccc ttcatagtta
     1561 tacggtgcgt cagtaatagt ttttccagta gaatatttca aatattcaaa agctggtccg
     1621 taatctgtga caggtttcat cgtagaacca aaatcacggg aagtattcac tgctaagttg
     1681 ttgcctaaag ttacgtcttc tgcgatgtga cgtccgccaa tctgggcttt tactttcccg
     1741 gtattggtgt cgataagggt ggaggcaact tgcatctcgt cgtctgggta agagacatac
     1801 tgatccgtgt tgacgatatc atatagtttc ttttgggcgt ccagatccaa attcgtataa
     1861 atctctaaac cgtctgtgta gacattctta tctgtttttt cttgtacttc attgatgact
     1921 tctttgacat aattatcgac gatcttagta ttgtcatcgg attgagttag ttcttgcaga
     1981 ccatccgtta ccggtacatt aacagcttga tcatattctg tttgagagat tttttcgttt
     2041 tgaagcatcg tatacaaaac agtatctcgt cttttcttcg cctgatctgg ataaacataa
     2101 ggatcatagg cggaaggggc ttgaggcatc ccagcaagca atgctgtttg cggtaaagaa
     2161 agttctgata atttcttacc aaagtacatc tcagaagctg tctccatccc gtacaagccg
     2221 tttgacatat acactttatt tacgtagtag gtcaagatct cttgtttcga ttttttttgt
     2281 tccaatctta cagccatcca cgcttcttgg gccttgcgtt tcagagtctg atcctcggca
     2341 ctggtggaga agaaggaaag tttgatcaat tgctgtgtca aagtacttcc gccttgcagt
     2401 ccgccagagg taaagttaga gagggcagaa ccgatgatcc gaatagggtc aaccccgatg
     2461 tgtttataaa aacggcgatc ttctaccgac acgatcgcat cttctaatgt tttcggtaat
     2521 tcattcgcag aaattttttc acgcttttct gcgcctaaat cttcgaatag ttcgccatct
     2581 tgtgtatata gtttggaaga tacggtagcg tctaattttt tatccgtcaa ttcgggcgca
     2641 tcttttgcgt aataccagaa aagtcctaca cctgctaaaa agaggataca gaaaaatgag
     2701 agtattccta aaaggatctt gataaataat ccttttttat gtgttccaga ggactttcca
     2761 gaacctttgc cagaattctt cttcacactc tttttaggag taggctgttt ctgtcgtcta
     2821 gagcttctag tttgttcatt tgccattctt gctttctcct tcaatagata atgttgataa
     2881 atagaagtca accgcgtcca aataaggaat ccgcggagaa ataccagttt tgatctctat
     2941 tcctagttct tcgatcaaag ataaaggtag tgatttgcgt cctttttcct tttgggcgtc
     3001 ccagtaagca atcaaatgaa cactattcaa ataaaaacag cgcttcaaag acgaaaacca
     3061 taacaagaca aagcagaccc cattttgttc gaggcatgct ttcatatgtt cgatttgatg
     3121 ggcatggaag tttttaaagg gaaaagatgt tttgttcttg gtttcttttg cttcaaagtc
     3181 caagtaaaag cctcgataga cgccattata gtctgtagtt gaggcttggg taaagtaggc
     3241 ttccttgatc acagcagcac ttctcttagg atagtctact ttcacgattt ggataggggt
     3301 aggcttttta tggataaccg ccaacccgcg ggaaagataa tatttattac tttcattgat
     3361 tgcttcttca aagcgcatcc cccgattgcc gaattcagtg atctgatttc ttttttcttg
     3421 aattttttcg acgggagagg cattcttata ataaggttgg ccatttggat agcgcaatac
     3481 catctttaat cacactccta ggccacatta tagcaaaaaa gcggatagaa agaaaaggaa
     3541 tctgagatgg ataagtcaaa agtaatctat gtgtctgggt atcgaagttt cgaactcggt
     3601 gtttttaaag aaaatgatcc taaaatccaa gttgttaaaa atgttttaaa aaaagaactc
     3661 catcagttag cagaagaagg gctggaatgg gtacttgtca gtgggaattt gggcgtcgaa
     3721 ctatgggctg tgcaaatagt agcggaattg aaagaagaat atccggaact atctcttggt
     3781 attttgtatc ctttttctga ttttggtaat aactggaatg aagggaacca agaaaaaaaa
     3841 caattagcag aacaattagc agattatgtc gaagctgtta gccatcaacc ctaccaatca
     3901 cctagtcagc taaagaatca cactcgtttt atacttgagc atacagtggg ctgtctgctg
     3961 atctatgatg aagaattccc tggaaaaacg aagtattttt ttgaagatgc acagaattac
     4021 caagcagatc atccctacga aattcggctg atcagtatgg acgatcttca aaattttagt
     4081 gaataatcga tattgtgttt gatttatcaa cttttttcct atacaatgaa aaaggtagaa
     4141 atgttattac gtaaatgaaa actagaggtg taaatatggc gaatttggtt tatagtccta
     4201 aagacatttt acaacaagaa ttcaaaacaa aaatgcgcgg ctatgatccc gttgaagttg
     4261 atgaattctt agacaatatc atcaaagatt atgaaactta cagcaaagaa ctccttgctt
     4321 tacaagaaga aaacgatcga ttgagtgcaa aagtagctca attatctaaa actcaaggag
     4381 cagctcaaac acgcgtgcaa caaacagagg caccaaagag cgcagcagtg accaattttg
     4441 atatcttaaa acgcttgtca aatcttgaac gtgaagtatt tggtaaaaag cttgatcaac
     4501 aagcaagtgc agtcaaacca gcacaaccta atccaaataa ctacacaaat gcagacacaa
     4561 gcttagatga taatgaaaaa acacgtcaat tttaattttt gattaatgaa tttgcggttt
     4621 tcgggtaatc gcggtctgac ttgatcaggc tgaggaaagt ccatgctcgc acaggctgtg
     4681 atgcctgtag tgttcgtgct tagcgaaacc ataagctaag gtactctttg gagtaacggc
     4741 aggaaaacaa gctaaggctt cggctatgct taagtatcct tgaaagtgcc acagtgacga
     4801 agcggctggg gaaacccatc cggtggaacg cggtaaaccc ctcgagcgag caacccaaac
     4861 aatggtaggg gcgctttttg tctggaagaa gaacaggaca aaaaggcagt ataactgcag
     4921 atagatggtt accgctttgt tttttctccc tggaaaagca aagtacagaa catggcttat
     4981 agaaaaccgc aaacatcagg gaattaggtc gtgacaaaag taatgcgtta taagaaacaa
     5041 gaaaaacatt tgaaagctat ttttcaatac ttcagatgaa tcgttcttat tacaaaacaa
     5101 acttttgtat caccggttat tcggaatttg agtaaaagtg tggggtagga ctgatgtccc
     5161 acctcctttt tttataaata aggagattgt gtatggaaaa aaacaggaag ttcaacctcg
     5221 tcgcaactgc ggcaagcggg ctagaagcac tggttggtaa agaattaaga gatcttggaa
     5281 tcgaatgcca agttgagaac ggacgtgcac gttttgaagg aacaatggaa acgatcgcta
     5341 cagctaattt atggttacgt acagcagatc gagtaaaaat cgtggttggg gaattcgatg
     5401 cgtatacgtt tgatgaattg tttgaaaacg taaaagcatt gccttgggaa gattttcttc
     5461 cactagatgc agcttttcct gtagctggaa aatcgatcaa gtcgaaacta tatagcacac
     5521 ctgattgcca agcgatcaca aaaaaagcaa tcgttgaacg tctccgtacc tattatcacc
     5581 gtccagcttc tgtaccactg acggaaactg gcgcacattt tcagttggaa gtagctttgc
     5641 tgaaagacca tgtgatggta actctggata cgacaggacc aagtttattc aaacgtggtt
     5701 atcgcttaga aaaaggtgga gcaccattga aagaaaacat ggcagcagca cttattatgt
     5761 tgacaaattg gcgaaaagac cgtccatttt atgatcctgt atgtggttca ggtacgcttt
     5821 gtattgaagc agccttaata ggccataata tcgcaccagg attcaatcgt gagtttgctt
     5881 gcgaatcttg ggattggttc agtcaagaaa tcatggaaaa tgttcgatca gcagccgaag
     5941 aaaaagcaga ttatgatatt gaattagata ttactggttc agatatcaat ggacggatga
     6001 ttgaaattgc caaagccaat gcagaagaaa tcggattagg ctcttcgatt acctttaagc
     6061 aacaagcagt caaagacttc aaaacggata aagaatacgg ggtcatcgtg gctaatccgc
     6121 cttacggaga acgtctagga gaagaagaaa ctgttcggaa attatataaa gaaatgggcg
     6181 atgtattccg tccattaaaa acatggagta aatatatctt gactagcgac ttagcgtttg
     6241 aggaatttta cggacaaaaa gcaaccaaaa aaagaaaatt gtacaatggt gcattgcgta
     6301 cggatctatt ccagtattgg ggaactcgtc cgcctagaaa aaaagagaaa gacgaataat
     6361 cttactaatt gattcattca attggatgtt tggaggaata gggaatgaaa gaaaaagagt
     6421 ttttacaaga agtaaaagaa atcaatcttc tacaacaagc tttaggaatc ctcgattggg
     6481 atacacaaac aggtatgcct gaaaaagcta gtgcataccg aagtgaagta gacagctatc
     6541 tttacggcat ttatttttca aaaaaaatcg gtccaaaaat caaagaagcc attcgctatt
     6601 tttctgaaca tccggaagaa ttgtcggaag ttggaactgc cgtttttgcc aaagtaaaag
     6661 aagagtatga tttggaacat cgcgtaccgg aagatcttat gagaaaatat acagctgccg
     6721 tttcttcagc acacggacaa tggcaaaaag ctagagaaac acaacaattt tctgattttc
     6781 aacacgcatt gaatcaaaat attgaattaa caaaacagtt gataccttac tggagaaaag
     6841 atgaaaagac gaattatgat gttttgctga atcaatacga acccgggatg actgtcgaaa
     6901 tccttgataa ggtatttgat cagcttaaag aaggaattct ttcgatccgc cgtacgctcc
     6961 aagaaaaagg gactgaacct gaaacagact ttttaaatcg gagaatgacg aaaaaacaac
     7021 agaagagatt tgtagtgaaa gtaatcgaac aacttggtta tgattttagt cgtggtcgtt
     7081 tagatgacac tgtccaccca tttatgactg gaattaatcc gaatgatgca cgaatcacga
     7141 cacgatggaa cgaaacagat ttcaaaatgg ctgtttttgg agtgatccac gaggctggtc
     7201 atggtatgta tgaacaagac atcgatgata aatatgcgta tacaccggtt tatgaaggta
     7261 catcaatggg tatccatgaa tcacaatcgt tgtttaacga gatcattatt ggaagtagtc
     7321 gcagcttctg gaaaaagcaa tatcctttct ttcaagaatg tgcagaagga acattcgatg
     7381 atattccttt tgacaaattt tatcgtttat tgaaccatac aaaatcaagt ttggttcgta
     7441 tcgaggcaga cagtttgact taccctctcc atatcatcat tcgttatgaa atcgaaaaaa
     7501 tgattttcaa tgaaggggta gatgttgctg aactacctga aatatggaat caaaaatatg
     7561 aagagtatct gggaatacga ccaacaaatg atgtggaagg catcctacaa gacgttcatt
     7621 ggtcaggtgc aagctttggt tattttccct cttatgcatt agggtacatg tatgcggcac
     7681 aattacttca ttctttgcag caagaaatag atgtggaaaa tgttctagcg tcagacgatt
     7741 attctccaat caaaaactgg atgtcagagc atatccatca atatggtgca tctagaaaac
     7801 caaatcaatt aatcatggat gcaacacatg aaccgcttaa tccgcaatac ctgatcgact
     7861 atatgaaaga cctgtatttt aatgtatatc aggtaaaata aaatacaatt tacaaagata
     7921 gctgaaattc atctaatcta tagatgtttt cagctattta cttaagaaag aagtggaacg
     7981 aatggataaa ttacaagtga tcgctgatta tagtatggac caattagcgc atgatcaaac
     8041 aggacatggg agcgatcata ccaaaagagt tgtcaagtta gctgaaaaaa ttttggagac
     8101 ggaaccgcag gcagaccgct ttgtgacgct tgcagcagct tacctacatg atacgattga
     8161 tgataaagtc gttaaaaatg agaacgaggc aaagcaacag cttcgtgtat tccttcgctc
     8221 tttgccaata gtagaggaac agatctcgat gattttttcc attatcgaaa atatgtcctt
     8281 ttctaaaaat ctctctgaag cggccgaact atctctggaa ggtaagatcg ttcaagacgc
     8341 tgatcgtatc gaagcattag gagcaatcgg cattttgcgt actgcttatt tcggcggtgg
     8401 acatgggcac ccgatttttg atcctgaact gtatccgcaa acattcaagg acaaagaaaa
     8461 ttaccgaaaa ggcacgacag tgatcaatca tttttatgaa aaactgttct tgctgtctga
     8521 taaaatgaat actgattacg gatatgaaga agccaaacga agagaaacct tcatgcgtga
     8581 attcttagaa gaattttttc tggaatggtc tattgacgat gaaaatttta ctccagacaa
     8641 ttggatcaaa aataacaaaa aatgatggag gttgtgacag aagtggtcag ctccaagata
     8701 tttcggatca ttttccgtaa aagttacttc tggaacactg tttaccaaga ggtcgtgagc
     8761 ctgccgttca gctccgagtc acaaggaaca atttcaaaaa atagcttctc gtgtttgatg
     8821 aatattgtaa cttgtgattc ggaattggca ggagaacacc gtttattcgg aagaatagga
     8881 ctgtgacaag acttttgtca cagtcctttt ttcgaattca acaagtaaaa cttttaagaa
     8941 atattcagag agtaaaatta aaaattgctg ataaacgaag atggaaattt tatgtatttt
     9001 tattggtcta tgcaataaat aaattaaata ttcagaatac aattgatttt aacgaaaggg
     9061 cttctatcaa tggttgtgtt gtatttatct gcccaggtag agtaaaatag atcattatct
     9121 aaaaggtaat tgttcatact atataagtca tttgaaagta aaaagatact gtaaataaaa
     9181 aatgtggtta aataattctc ataatcagtg taagcgttat caaaaatata gcatacttgc
     9241 tttgtagatg aatgacacga tatatgtttg gtatgttctg caagacagat gaatatggag
     9301 gtggagacaa tgtcttccaa agaactaaca atgtatttag agaaagaatt ggatcaactg
     9361 aaagaaaagg ggttatacaa tacgatcgac atactagaaa gtgaaaatgg tgcttgtatc
     9421 atcgtagacg gaaaaaagat gatcaatcta gcatccaaca attatcttgg atttgccaat
     9481 cgcgaagaat tgaaaaaagc atgtattgaa gcaaccgaaa cttatggtgt aggagcagga
     9541 gcagtccgaa cgatcaatgg ttcgctgaaa atccatcagc aattagaaga aaaaatcgca
     9601 gaattcaaag ggacagaagc agcaatcgcc tttcaatctg gattcaactg caatatgggc
     9661 gctatctctg cagtaatgac aaaagaagat gctatcttat cggatgaatt aaaccatgca
     9721 tctattattg acggttgccg cttatccgga gcaaaaatca tccgaattaa acatcaagat
     9781 atgaaagacc ttgagaaaaa agcaaaggaa gcgatagaaa gtaagaaata taaaaaaatc
     9841 atgtatatca cagatggtgt tttctccatg gatggagaca ttgcacgatt gccggaaatt
     9901 attccgattg ttgaaaaata tggactgatc acctacgtcg atgatgcgca cggctcaggc
     9961 gtaactggaa aaggtgcagg aaccgtcaag cattttggat taagcgacaa aatcgatatg
    10021 caaatgggca cgttatcgaa agctataggt gttgttgggg gttatgtagc tggatcgaaa
    10081 acactaatcg actggttgaa agctagaagt cggccattcc tattttctac ttcgctaact
    10141 ccaggtgcag ctgcagctgc attggcttcg attactttga tgcaagaaca tccggaactt
    10201 gtcgaaaaag tttgggaaaa tgctaattat tttaaagaag aattgaaaaa agtaggctat
    10261 aacatcggta tgtctgaaac acctattact ccagtcattt tgggagacga aaaagtgact
    10321 cagactttct ctaagaagct gatcgaacat gggatttatg ctaaaccaat cgtttatcca
    10381 actgtgcctc ttgggacagg caggatcaga aatatgccga ctgcggaaca tacgagggaa
    10441 atgcttgatg aagcagtagc agtttatcaa aaaataggaa aagaaatgga aattatttaa
    10501 ctaaatttag ttttttcgtc tatttaaaat tagagaacat gttcacgcat atattgttaa
    10561 tcatctgaag atagtagtaa aaaagatcag ggaggatcat catgaaaaaa gtattggtga
    10621 caggatgttt aggacaaatt ggttcagagt tgatcacacg gctacgtcaa gaactaggca
    10681 gtgaaaatgt cattgcgaca gatatacgca tgcctgaagt cattgagaaa aacgatatct
    10741 ttgagatcct agatgtaatg gattacgaaa aaatgcgcag catagcagaa caatatcaag
    10801 tggacacatt gattcatttg gctgctcttt tgtcagctgt tgcagaagca aaaccacaat
    10861 tagcctggaa tttgaacgtg actgggctgg tcaatgcatt ggaagtcgct agagaattcc
    10921 agctgaaatt ttttacgcca agttcaatcg gcgcgtttgg tccaaatact ccaaaagatc
    10981 ataccccaca agatactctt cagcgtccta caaccatgta tggggtaacg aaggtagctg
    11041 gagaactact atgtgattat tattatgtga aatatggcgt agatactcgt ggtgtccgtt
    11101 tccctggatt gatttcttat gcaaccttgc caggaggcgg tacgacagac tacgcagtcg
    11161 atatttatta ttcagcaatc aaagaaggaa agtacactag tttcattgat caaggtacat
    11221 caatggatat gatgtatatg ccagatgcga tcgatgccat tataaaactc atgaatgcag
    11281 atcctgatcg attggttcat cgaaatgcct tcaatatatc ggcgatgtct tttgacccgg
    11341 aagagatcaa agcatctatt caaaaaatca taccagattt tgaaatggat tatgatgtgg
    11401 atcctgtacg tcagtcaata gcagaatctt ggccaaattc actagatgtt tcttgtgcgc
    11461 aagaggaatg gggcttttcg ccgaaatacg acttagatgt gatgacaaag gatatgttgg
    11521 aaaaactgaa agaaaaattg gtagagacgg tataaaacaa gaaccacatc caaaaagttt
    11581 tttatacttt tgggattggc tatggtatga aaggggacaa gggatggaag aatatcaagc
    11641 cacgccagta aaagaagtaa aaatagaaaa tgaattaaaa cgtacgatgg gattttttac
    11701 tgctttatcg actgttatgg gcacagtgat cggtgcaggg gtatttttta aagccgcaag
    11761 cgtagcagaa gttacaggat ccgccagttt gcatatgttt tcttggtttc tcggtggtat
    11821 gatttctgtc tgtgcaggac taacaggagc tgaactggca gctgctattc cagaaacagg
    11881 agggatgatt aaatatatcg aacggattta cggaaataca gcagcttttt tattgggctg
    11941 ggcgcaagtc gtgatttatt ttccagcaaa tgtagcagcc ttgtcgatca ttttcggtac
    12001 acagttcgtc aatctatttg gtctttccca gtcaatgatt gttcccgtag ctgttacagc
    12061 tgctgtatcg atcctgttga tcaatttttt aggttctaaa gctggagggg cttttcagtc
    12121 gattacgctt gtctgcaagc ttattccttt gtttgtgatc gtcattttcg gtttgttccg
    12181 acaagaagga gtagacttcc aactgtttcc gatccaagca ggagaaaatc tttcattttt
    12241 ctcagccttg ggagcgggct tgctagcaac gatgttcgca tacgacggtt ggatacacgt
    12301 aggaaatatt tcgggagaat tgaaaaagcc ggcgaaagat ttgccaaaag caatttcttt
    12361 aggaatcatc ggaatcatga tcgtttattt attagtaaat gcggtgttct taagaaccgc
    12421 atctatcgac ggagtcgcag gaaacagcaa tgcggcaagt gacgttgcaa aaatgatttt
    12481 tggcggcttc ggtggaagac tggtcacagt tggtatcttg atttctgttt atggaaccat
    12541 caatggctat acccttactg gaatgcgtct cccttatgtt atggcaaaag aaaacaacct
    12601 gccttttagc aagctctttg ctaaacttca tgataaaact aaagttcctg tagccgcagg
    12661 tatcttagag ctagtcatcg ctattggcat gatgatgatc ggtggttttg atacactaac
    12721 ggatatgctg atctttgtca tttggatttt ttatacgatg gtctttgttg gtgtcattct
    12781 tcttcgtaaa aaagaacctg atttgtttcg accatacaaa gttccaatgt atccgtttat
    12841 tccactagta gcaatcattg gagggacttt tatcgtatca agcacgctta tcactcagac
    12901 ctttttagct tcgatgggga tagtattgac acttgctggt atcccgattt atctctattt
    12961 aaaacgtaga tagctaaaac attcgaattt tattagaact gcacttctct gccaaacaaa
    13021 atattttatt taaatgagga gtacgtggaa gaaatgtcaa aagtactcgt taattttgat
    13081 cacgtaaatg tcgttttgtc tacgatgaaa tagcaaagta aaagacagaa atcgggctca
    13141 accgatttct gtcttttact ttgatttgcg taactgaact attcggcgta cgccgcgata
    13201 aatatttaat aaaaccaagc aaccagaaat gaaaatggga agccaaatca gatagacagg
    13261 gtagccaagc actttagaca aagcatgtgg agtcatttta tccatttcaa gaagtgcttg
    13321 ctgccaagtc tgaagattga agactagcat gaaacccgaa ataatcagga gaataaatcc
    13381 taaataatga attgtagttc tttttcttac ataagcgatc gtagcataaa ggaacagtaa
    13441 aaaaataggt acgccaaaaa caaagtacat attcagcatc tcgacacccc ctttgtgttt
    13501 atcttacttt actttgaaag aaatgagaaa taatagcctc gttacttgct tgaaacagca
    13561 aaggactgct aagataagag agatacaaag aatcaaggag gagtcatatg gcaagttata
    13621 tcgaaccgat tcgttttgcg ctgattgttt ttccattttt agccttagcg atctcatctg
    13681 ttttttttat ttatgaatat cgaaagtatg gaacatttct agtaacaagg gcagttattt
    13741 tgtattcttt cgttttttat ttattgtgtg cgtatttttt ggtgatctta ccacttccgg
    13801 caaaggagac ggttgcccaa atgacagggc caaagatgga gctgcattta tttgcttcat
    13861 ggcaacattt cagagacaac acggtattgg tcttgtctga acctagtacc tacctgccgg
    13921 caatgaagca gagtgtattt ttggaaccag cttttaatgt tttattactc ataccatttg
    13981 gcatttattt aagatattat ttccggcttt cttttatgaa aacgatgatt gctagtttct
    14041 gcctttctct attttttgaa ttgacgcagc taagtggact ttattttatc tacccaagac
    14101 cataccgctt atttgatgtg aatgatttag tgacaaatac attgggtgga atcattggtt
    14161 ttgtcgttac gccgttattt acatttatgc ttcctacaag aagacgaatg gatgaacttt
    14221 cttatgaaaa aggaaagact gtctcattga ctcgacgctt ggtcgcttat ttgatcgact
    14281 ggacattttt atctcttatt aatttggtag cggcgatttt ctttaaaatt gcgttcgatt
    14341 caggggcagt tacttctcat atctggtggc ttttattaga agtaggggta tactttatga
    14401 ttgtaccgtt tataaccaat ggatggacac ttggcaaaaa aattgtgcgt atccgtttgg
    14461 tggaagaaga ccgcgaacga atttctttaa aagcattgat gatccgctac gggtatctgt
    14521 actttctttt ttatggttta agctggttgg ggcagttgct tcagcaaatc atgaattcga
    14581 caacgaatac ggtgttgcag atgagtgcag tattcatttc tctcggtgtc ttgttactac
    14641 aaggtatttt tattttaaat atcttgctat catttttgag aaaaaaacgg attctgtttt
    14701 atgaaaaagc tagtcacaca tatactgtta gcacgattgg ccaaacaaag gatgatgatt
    14761 ctcgaaatta gctgagcaaa aacgctttgt ctgtgttata atgccaaagt cgtgataatt
    14821 taaagagaag aggtgcacga atgaataatt ttgatatatt ccgcttcaaa ccgtttatca
    14881 atgaagcgtt aaccgcaaag ggcttcaaac agcccacaga ggtccaggaa cgtttgattc
    14941 ctttaattgc aaaaggaaaa aatatcattg ggcaatctca aactggtaca ggaaaaacac
    15001 atacgttttt gttgcctttg tttgaaaaaa tcaatgcaga aaaagaggaa gtacaagttg
    15061 ttattacagc tccaagtagg gaactagctg cacagatcta tgaagcagct acacaaatcg
    15121 ctaaattttc tacaccggag atccgtgtct cgaattttgt cggcggtaca gacaaacagc
    15181 gtcaattaaa tcgtctgcat caccaacagc cacaggttgt agtaggcacg cctggtagaa
    15241 tattagacat gatgaatgaa caagcgctga agattcacac cgcatttgca tttgttgtcg
    15301 atgaagcgga tatgacattg gatatgggtt ttttaaatga agtagaccaa attgcaagtc
    15361 gattaccaga aaagctgcag tttttagttt tttctgccac tattccagaa aaacttcgtc
    15421 cattcttacg aaaatacatg gaaaatccaa tcattgaaga aatcaaacca aaagcagtta
    15481 tttctgaaga cattgaaaat tggctgattt caacaaaagg taaagatgag aatcaaatga
    15541 tttatcaact gctgacaatt ggtcatcctt atttagcaat cgtatttgcc aatacaaaac
    15601 agcatgtgga tgaaattgcc gattacttga aaaaccaagg cttgaaagta gcaaagattc
    15661 atggagacat caccccaaga gagagaaaac gagtgatgcg acaagtacag aatctggagt
    15721 atcaatatgt tgtagcgact gatttagctg ctagagggat cgatatcgaa ggtgtctctc
    15781 atgttattaa tgcagaaatt ccagaagatc tagacttctt tatccatcgt gtcggacgta
    15841 ctggacgtaa tggcttaaaa ggaacggcca ttacgttata ttcgccaaat gatgagcaag
    15901 ccattgatgc gatagaaaaa ttgggcgtct catttgaacc aaaagaaatc aaaaacgggg
    15961 aaatcgtcaa aacatacgat cgtaatagac gtgccaaacg agaaaaatca aaagatgtat
    16021 tagatcccac gctgattggt cttgtgaaga agaaaaagaa aaagatcaag cctggttata
    16081 agaaaaaaat cgattgggca attgcagaaa aaaataaaaa agaacgcaaa atcgaacgca
    16141 gacagcaaag ccgtactgct cgtaaaaata agaaaaattc acataaataa aaaacaagag
    16201 gttgtgacaa aaggcgtgtc acaatctctt gtttttaagc tagacttttt ttcattccga
    16261 tacaaagtac ttcatcttca ataaaaggtt ctgtgcaagt atgataccct tgtttttcat
    16321 aaaaatctac agccgtcatt tcagctacta cataactagt ctgacaacct tctgaaaccg
    16381 cccgtttttc agcagcttca agcaactgac cgcctaaccc ttttcctcgg tattcttttg
    16441 ctacgcaaaa tcgttccggc ttgaagcaag taggtgtttt cttttcataa cgcaaagtag
    16501 ctactggtct tttttgatca agaaatagat aataggtttg ttgcgggata tcttttccgt
    16561 cgaattctag ttctgcagga atcccttgtt ctaatacaaa aacttgatat ctcaaaaagc
    16621 agctagctgc gcgtatccat tcatccgctc caactatttt tttcatcata ttcctccttg
    16681 tcatgaatag cagagatgta ttgattcctt tattcttatc gtaccaaaaa tcgtggagta
    16741 tgaccaaaag gaaatgaaaa taaaaattga gatattgaca gtgatcaata gaatgcgtat
    16801 actaattaag tacgaaaagg atatgatttg ttttttaaga ctcacagaaa attctttctt
    16861 ggctgaaaaa agaatagtca ctaatcaaat tgctcccttt ttctattttg gtagaaatac
    16921 cgacgcagct cagcgttatc gagtttaaga ggtaatgatt acacatcatt gcaatcaagg
    16981 tggtaccgcg agttttcgtc cttggctgtg atggtgtttt tttgtattta atttatagaa
    17041 agcaggtaat gacatgaaac aattaagtag tgcacaagtt cgacaaatgt ttcttgattt
    17101 cttccaatct aaaggacata cgattgaacc tagtgcgtct ttgatccccg tgaacgatcc
    17161 aaccttattg tggatcaact ctggtgttgc aacattgaaa aaatattttg atggttcagt
    17221 tgtgccagaa aatccaagaa tcacaaatgc ccaaaaatct attcgaacaa atgatatcga
    17281 aaatgtcggt aaaacagcac ggcaccatac gatgtttgag atgctgggta atttttcgat
    17341 tggtgactat ttcaaaaatg aagccatcca ctgggcatgg gaatttttga ctgatccaaa
    17401 atggatggca ttcgatccag aaaaacttta tgtaacagtt tatccaaaag atacagaagc
    17461 aaaacgcatc tggcatgaag aagttggcct gccactagat cacattattg atgtagaaga
    17521 caacttctgg gatatcggtg caggcccatg tggtccggat acggaaattt tctatgaccg
    17581 tggagaagct tataacgatt tagcagaaga cgatcctgaa aactatccag gaggagaaaa
    17641 tgaacgttat ttagaaatct ggaacttagt attttcagaa ttcaaccata agcctgataa
    17701 cacatttgaa ccacttcctc ataaaaacat tgatacgggg atgggattgg aacgcatggt
    17761 ctcaatcgtt caagatgcgt caacgaactt tgagacagac ttgtttatgc ctattatcca
    17821 cgccgtagaa aagctaagca aacaagtaaa atatggtgaa aacccagtaa cagatatttc
    17881 ttacaaagta atcgcagatc atattcgcgc cctttcattt gctattggcg acggtgcatt
    17941 gccatcgaat gaagggagag ggtatgtctt acgccgtttg cttcgtcgtg ctgtcatgca
    18001 tgggaaaaaa ttaggtattg aacaagcatt cttatatcgt ttagtccctg ttgttgggga
    18061 aatcatggta agttattatc ctgaagtact tcaacaaaaa gaatttattg aaaaagttat
    18121 ccgtacagaa gaagaacgtt tcaatgaaac aatcaatgaa ggtttggaaa tcttaaatca
    18181 agtgatccaa gaagtaaaaa acgaaaacgg gacgactcta gcaggaaaag acatcttcaa
    18241 actatacgac acatatggct tcccggtaga attaacggaa gaggtggcag aagatgaagg
    18301 actgaaagtt gatcatgctg gttttgaaaa agaaatggat gcacaacgcg aacgtgctcg
    18361 ctctgcccgc agtactgaaa aatcaatggg ggtacaatct gctttattga cagatatcaa
    18421 agtagaaagt aaattcattg gatacacaga acaagaatca gatagtcaat tattggtcat
    18481 cgttaaaggt gagtctcttt tgaatgaagt cgcagaaggt gaagctcaaa tgatctttga
    18541 tcaaacacct ttctatgcag aaatgggtgg gcaagtagcg gatcaaggat ggatcatgaa
    18601 tgaagtaggc gaaatcgtag cagttgttac agatgttcaa aaagcgccta atggtcaatt
    18661 tatgcacacc gtagaagtaa aagcaccaat gagtgaagga caaacctatc atctattgat
    18721 cgatcaatcg atgcgcaatc ggatcatcaa aaaccataca gcaacccatc tactgcacaa
    18781 ggcattgaaa gaagtacttg gcgagcatgc aaatcaagct ggttctttag tcgctcctgg
    18841 acatttacga ttcgacttta cccactttgg tcaaatcact tcagatgaat tagctgaaat
    18901 ggaaagaatc gtcaacgaaa aaatctggga agctatccca gttgaaacaa ttgaaacaga
    18961 tatcgataca gccaaaaaca tgggtgcaat ggctttgttt ggtgaaaaat acggacatga
    19021 cgttcgagta gtaaatattg gcggctggtc aatcgaactg tgcggaggca cacatgtagc
    19081 aaatacagaa aacatcggaa tcttcaaaat cgtttctgaa tcaggaattg gtgcaggcgt
    19141 gcgacgaatc gaggctgtaa caagtaaaga agcgtacgaa ctacttgaag aagaagaaaa
    19201 acaactaaaa caagtagcaa caattgttaa atcacctcaa ttgaaagaag ttgtttcaaa
    19261 agcggaacaa ttgcaacagc aagtaagaga gctacaaaag gaaaatgaac aattagctag
    19321 caagttagcg aatcaacaag ctggtgatgt attcaaagat ccagaaacga tcaatggaaa
    19381 aacaatcatt gcagcacaag taaaagtgaa agatatgaat cagctgcgtc aattagctga
    19441 ccaatggaaa caaaaaaata tttcagatat tcttgtttta gcaaacgaac aagaaggaaa
    19501 agtcagtctg ctagcggcaa tgacgaaaga atcaaatgaa gctggactaa aagctggcga
    19561 cttgattaaa gcaatcgcac cgaaagtagg cggtggcggt ggtggacgtc cagacatggc
    19621 acaagctggc gggaaaaatc ctgctggtat tccagatgca cttaaagctg cgaaagaatg
    19681 ggttgcgcaa caatagggcg tttacgtttg acagaaaaac aaaagttcaa acattgaacg
    19741 aaacatgatt atgggggcga agacaaacaa gtcttgccct catacttttt tcaattggat
    19801 ggcgcatcta atcaaatggt cggattcgga tggtctttag ttgacgaaag tgacagaaat
    19861 ttttacgatt agtataaata aaaaggggtg aaaaaatgaa tagtagaaat aagacctttc
    19921 gactagtctt acgtgcgatc ttgttagcaa tcatcatcgt acaagcgatg gttccttggc
    19981 tggggtttat tccattagga ttcattagtt taacaattat ccatatcaca gtaattattg
    20041 ctgcagtagt attaggccca aaagatggca tggtgattgg cttgttttgg ggaatcgcta
    20101 caattgttcg tgcctatgcc atgccaacaa cgccatttga tacattagtg ttcacgaatc
    20161 cgattatctc ggtagttccc agagtacttg ttggcttagt agcaggcttg gttttccact
    20221 ggatttatca aaaaaataaa tcaataacga tcagctcagc ctttgcaggg gtactgggtt
    20281 cattggtcaa tacagtctta gtgttaggat tcatgggatt attttataca ggtgcaacgg
    20341 cagatgccta tggtgtagac tctgctcttt tatttaaaac cttagcaggg gttgcagcaa
    20401 tcaatgggat accagaagca ataggtgcgg gaatcataac accattacta gcaaaagcgt
    20461 tatttgcagc aacaccgttg aaaccagaat aatgaccatc ttttaatagt aataggacgc
    20521 acgatagata gaaaaaggaa gagaggagag gaaaacaatc gtcctctcca tctttttacc
    20581 tgagcaacaa gcaaactaga aggggtaaaa aacttggcta agaaacaaga agaaaaaaag
    20641 aaacaaatac cgcaacagcg gacaaaaaaa ggagtactag cgggtatctt aggattggtt
    20701 acgaatctga tcttgtttgt ctctaagcta atgatcgggc ttttttcagg aagtgtctcc
    20761 attatggctg atgcagtgaa cagtctatca gatactgctt catccatatt gactttgatc
    20821 ggatttaaaa ttgctgcaaa gccagcagat caggaacatc cttatggaca cgaacgcttc
    20881 gaatatatca gtgggttatt tgtttcgatc atcattactt atgtaggatt tcaattttta
    20941 gagtcttctg ctgaaaaaat catccatcca gaaaatgtct ctttaacacc catcgtcttt
    21001 tttgtcctaa tcatttccat ctttttgaaa tttgcacaag gcaaaatgta tcaggttatt
    21061 gcgcaatcca ttgattctga aacattgaga gctacagcaa cagatagtta taatgatgtc
    21121 tttactacac tggctgtatt gctttcagca gcaatcgaat gggtaactgg atggcgtatt
    21181 gatggatata taggttttgc tttagcatta tatatccttt atagtggatt gacgatgctt
    21241 cgaaattttg tatacgaact attaggaagt cgcccaacgc cagcagagat tgaagaaatg
    21301 gaagagcatt taaatgcttg cgatgatata cttggctatc atgatttatt ggtgcataac
    21361 tatggaccca ataaacgctt tgcatcagtc cacatcgaag tagatgaatc aatgaatttg
    21421 aatgtggctc ataagattat tgatctgata gaaaaagact ttaaaaagtc tttggatgtg
    21481 gaacttgtct gtcacttgga tccaatgcct gttgataacg aaaaatacta taatatcttg
    21541 cggcagttaa agcaaattct tcttgaaaca ggtacagggc ttaatattca tgattttaga
    21601 gtaattcatc aaggaaaaac gctgcaattt gatgtagtgg tccctgagaa attccagttt
    21661 gttgatacag aactagaaag aatcttacgt agtcaaatag aagaaaaaat cggagattac
    21721 caattggaaa ttacgtttga tcacaattat cttttatatt aaatgagaaa ctataaaaag
    21781 actccttaaa gtttttaatt taaagagtct ttttttcttt taattgttta tggagagcct
    21841 gacgtgcaag attatctgct cctttatttt tgttttcggg caaccattgc aggatcaata
    21901 aagaaaattc ggatagaagt tcttggattc tttgaaggta gggaaggaag agctcgttct
    21961 tcgttgcgtt tttgtcgacc gtagaaacta gtgttttgct gtctgaaaaa cagaaaatcg
    22021 tttcattctg taagtcgttt ttctttagaa attctaaagt ttttaaaaag acttcgaact
    22081 ctgcttgatg gtttgtccct atagaaagcg ggatagatag ctgttcttgt ttaccttgat
    22141 agacaatcaa gattccacct ccactaggac cagggttgcc ttttgtagag gcatcaatgt
    22201 atacttttaa cataaaaaga gattctcctt tttgttcaaa ctaatgttat ggtaagatta
    22261 tatcattact gaatcggtga gaggttagag aatgaaaaaa aatattcgat ggcagcctga
    22321 actggcacat acgatcatct attggtcatt gaccttgatc attctgtttt ttagtctgat
    22381 tctttcttta gaaaacacag gtccttattg gaaaagcaat tttgttttag gtatttttct
    22441 tgtttttcta tttctaggtt tgcggcgttc ttttatttta aaatcaaact ctgtgattat
    22501 acgttatgct gctttttgga aagaccgaga aatatctgtc ggacagattc gatctttgac
    22561 gccaactaat actggggtgc aaatgatgtt gcaagatgag aaagccccat ctgttttcat
    22621 gatgcgaaaa aaagatcaag tagtcctttt tgatcatttt gaaaaaaacg gacccaaatc
    22681 agaatcaatt ccttatcctt atacgaaaaa aagaaaaagc taattttaaa aatcagaacc
    22741 taaaaaaacg aatttttaca ggaaaagaaa agagtgagac gtacggttca tcccgtttag
    22801 cgtctcactc tatttgttta tctattcatg catactagta tcggtagtct gaacgttgcc
    22861 tttcttgaca tgggcagctt gtgttcctcg attcccttcg atgatctcaa attcgaccac
    22921 ttgattttct tccaaagttt tgaatccctc ttcttcaatc gcagtaaaat gtacaaaaat
    22981 ttcttctgtg tcatcataac tgataaagcc gtatcctttt ttgttgtcaa accattttac
    23041 aattcctgtg gtcaaagcac tcacgacctt tctaaagtct gatcatagcc ttcattataa
    23101 agagtattta taagtacgtc aaataaatta aaaacctgta attttatgtt ttttttctga
    23161 ataaaaaaag gtataattgg catatcttaa caaagaagat attttgttga ataaagttcg
    23221 tgaaaagggg taatcaaatg aagaatgatc tgcaaatttc acaagaaaca gagctagaac
    23281 cgattgttga agtggctagt aaattagatc ttaaggaaga cgatttggaa ctgtatggga
    23341 aatataaggc gaaaatcaat ttttctggaa tcaatcgatc aaaggataac gctgaggggc
    23401 atttgatctt agttacttcc atcaatccaa caccagctgg cgaaggaaag tcaacgatca
    23461 ctgtagggtt aggagacgcg ctcaataaaa tcaataaaaa atctgttatt gcattgcgag
    23521 aaccctcact tggtcctgtg atgggaatca aaggtggtgc tgcaggcgga ggatatgcac
    23581 aggtattgcc tatggaagat atcaacttgc attttactgg tgacatgcat gctatcacaa
    23641 cagctaataa tgcattatct gctcttttag ataatcatat tcatcaagga aatgaattga
    23701 acatcgatgc ccgccgagtg atttggaaac gggtagtcga tctcaatgat cgtgaactgc
    23761 gtaaagtaat tgttggcttg ggtgggccaa tccaaggtgt tccaagagaa gatgggtttg
    23821 atatcacagt tgccagcgaa atcatggcta tcttgtgtct tgcggcagac cttgaagatt
    23881 taaaggctcg tcttgcaagg atcgttgtcg gctatacatt tgaccgtcag cctgtgactg
    23941 ctggagactt gaaagcagaa ggcgctctgg cattactgct gaaagatgca atcaagccga
    24001 atcttgtaca aacaatttac ggaacaccag cttttgtcca cgggggaccg tttgccaata
    24061 tcgctcatgg ctgcaatagt attttagcta ccaagacagc attgagatta gcagattacg
    24121 ttgtcacaga ggcaggattt ggtgcagatc ttggcggaga gaaattttta gatatcaaag
    24181 tacctaactt gaaaaaagcg ccggatgctg tggtgattgt cgccactgtc cgtgcattga
    24241 aaatgcatgg cggaatgaaa aaagatgaac ttaaaaatga gaatcttgat gctttgaaag
    24301 taggttttgc aaatttaaag cgccatatac gtaatatgga acaatatcag ctacctgtga
    24361 tcgtcgcaat caatgaattc gtaacagata cagacaatga actcacactg ttggagcact
    24421 tgtgtgaaaa tcaggggatt cttgccaaga gagcgagtgt atgggcagat ggagcagaag
    24481 gcggcgttga tttagcaaaa gctgtagtac gattgattga tagaaaagaa gctaattaca
    24541 agccattata ccgcctagaa gaaacgatac aagaaaagac agaaacaatc gtcaagaaaa
    24601 tttacggagg aaatggtgtt gttttcagca aaaaagcgca aaaacaaata gaagagttta
    24661 cgaagaatgg atgggacaaa ctgccgattt gtatggcaaa aacacagtat tcattttctg
    24721 atgatccttc actgctaggt gcaccggaag atttcaccat cacgatccgc gaaatcatcc
    24781 caaaattagg ggcaggattt ttagtagcct tgactggaga tgttatgacg atgcctggtt
    24841 tgcctaaaaa acctgctgca ttgaatatgg acgtgacaaa tgacggagaa gtgttgggat
    24901 tgttttaagc ttgattataa tctaccatcg aaggagctgt attttgacta cagcttcttt
    24961 ttttagacga tagggaatta attttgttta cactaggatc attctttttc tttattgtat
    25021 tttgagctat actaaagcat aataggaggg tatgatgaaa acgacattta taagaaaaac
    25081 cggtttttac ggtatgggta gctcgattca gctaagaatc aacaatgaaa aacgcagtgt
    25141 tctcagtcat gaacaaaaga taacgcttga tctggaagtg ccctttacga tgcaggtcac
    25201 cttttattgg ctaaaaagcc ccgtttatac agtgaaagaa gcaaagcctg cttatgtgat
    25261 cacaatgaat tacttgattc ttcaaatcta tccgttttta tttctagcaa ctgggttggg
    25321 ggccgttttc ctacaaaatt tatttttcag tttttttgca gttattgtgt tgattgcgtt
    25381 ctttttctat ataaaaaacc gggcatattt gatcaaggag gaaaattatg gcaaactctg
    25441 atcttttttt aatcagtttc aatcgaatcg aaaaatggat gagagacgag atgggaaatg
    25501 cacgaaatat gggatttacc gaacttgtca gacgcctagc tcaaagaaaa caattaatga
    25561 tcagaaaata cgaagatgat cttttacagc ttgctcagtt aaggaatgcg atcgtccatg
    25621 atcggatcgc agtcgatttt gtcattgcag agccaaatga ttggacagtc aagcgaatcc
    25681 agctgatcga acaagaactg attcagcctg aaaccgtgct gcctcgattt gcaaaacgtg
    25741 taacaggttt tgaacaagat cttccgttac ttgaactgtt aaagatagta gcagaaaaaa
    25801 ggtattcaca atttccgtta tacaataaag gaaaatttgt agcattgatt actttacgta
    25861 atatcgggtt ttggctagca aaagaaagcc aaaaaggtcc ggttgattta acaaataaac
    25921 gagcgttgga tttgatcatc caaaacggaa agtacacaaa ttatcatttt gttccagcta
    25981 aaacacatat ttacgaggtt gaagcgatgt ttcgtgagca agggactttg gaagccgtac
    26041 ttatcactaa agatgggaat cccgatggta atctgctcgg gatcgtacga cctcgtgata
    26101 tttataaaca aatagaaaag gattgatttt ttgttaatta tttattggat attcagcgct
    26161 ttgctagtag gagtggatca gttggtcaaa tggtggatca ctgataatct agcgcttgga
    26221 gagacgaaaa atcttatacc aggtattttg tcactgaatc atattcgaaa cactggagcc
    26281 gcatggagta tgctagaagg gaagatgtgg ttctttacta tagtgacact cattgcagtc
    26341 gttgtgattc tcacattgat gattaaaaat cgtgaaaaag gtaatcgctg gttcatgatt
    26401 ggattgagtt tgattctagc tggtgcgatt ggcaatttta tcgaccgtat tcgtcttggc
    26461 tatgtagtag atatgttcca gacagatttt atgagctttc cgatttttaa cgtagcagat
    26521 gtgacacttg tatgtggagt gatttgtatg ttaatttata ttattttaga tgaaaaggat
    26581 caaagaaaaa aatgacagaa cttaaaacga cgattcacca tgaatctggt aggatcgata
    26641 aagtattgac taatttattc accgattaca gtcgttcgca aattcagctg tggctgaaaa
    26701 atggagcggt ttctgtcaat ggacagccag tcaaagcaaa ttacaaagta aaacaaggag
    26761 acgagattac tgtcttgatc cccgaaccag aaacattaga tgtggtccca gaaaatatcc
    26821 cgttgacgat cgtttacgaa gatgaagatg tagcggtgat aaacaaacct caaggaatgg
    26881 tcgttcatcc ttcagcaggt catacgcatg gcacaatggt caatgcgctg atgtaccata
    26941 tcaaggatct ttctacgatc aacggcgtta ttcgtccagg tattgttcac cgaatcgaca
    27001 aagatacttc cggactgcta atggttgcca aaaatgacca ggcacacgaa tcattagctc
    27061 agcaattaaa agataagacc tctttgcgca aatatgttgc tttagtccat ggagagattc
    27121 ctcacgaaaa aggaaccatc aatgcgccaa tcggccgttc gaaggaaaac cggaaaatgc
    27181 aggcgataag agaagatggg aagtcggctg tcacacattt tactgtattg gaacgtttcg
    27241 aaggatttac tctggttgaa ttaaaactag aaaccggaag aacacaccag atccgtgtgc
    27301 atatgaagta tatcggttat ccgttagctg gagatccagt atacggaccg aagaaaactt
    27361 tgaaaggcaa tggtcagttt ctccatgcgc aaatgttagg ttttacgcac ccgactacaa
    27421 acgaaaagat gatctttgaa gcacctcttc cagaagtttt tgaaaaaact ttagaaaaat
    27481 taagaaaaaa cattgcattt taatttagat aacggtatag taattaacaa cgaaagcata
    27541 aaacttaata gaattccttt aagtttagtc ccgtgaggct aagaagggtg ggagcaagga
    27601 tacgtatggt gcgccataag tagattgctc attgacatag tatagctatc agtgtatcag
    27661 tatacgctca gtctaaacat tcctcctgtc ctcttagggc aggagttttt ttatgcaaaa
    27721 aagtaggggg aatgaaaatg caagcaaaag aagtagtaga tcaggtaacc atgaagcgag
    27781 cattgactcg aattacttat gagattatcg agagaaacca tagtatccaa gatatcgtat
    27841 tggtaggtat caaaacacga ggaatctaca ttgcatcaag aattgccgaa cgcctgaagc
    27901 agctagaaga tatcgatatt cctgtaggag aactggatat cactttatac cgagatgaca
    27961 aaaaagaaaa tccagaagaa ccggaacttc attcttctga catcccagtt tccttagaag
    28021 gaaaagaagt tattttgatt gatgatgttt tgtatacagg acgaacgatt cgagcagcaa
    28081 tggacgcagt aatggatttt ggcagaccaa gaaaaatttc attagcagtc ctggtcgatc
    28141 gtgggcatcg agaattgcca atccgtgcag attatgttgg gaagaacatt ccaacatctc
    28201 gggcggaaga gattttagta gagatgcaag agcttgatgg acaagatcgc atcatgattt
    28261 tgaaagagga agattagagg agagagaaac atgtcggaga aaaaaggatt tcataatgat
    28321 gacgtggtgt tagatatcca cgatcgccca accccaggac attgggtagg attaagttta
    28381 caacacttgt tcacgatgtt cggagcaacc gtgttagtcc ccatcttagt aggtatcgat
    28441 ccaggtattg cgctagtcag ttcaggacta ggtacattgg tgtacttatt tactactaaa
    28501 ggaaagatac ctgcgtactt aggaagcagc ttcgctttca ttgcagcgat gcagcttttg
    28561 atgaaaacag atggttatcc agcgattgca caaggagcag tcacaactgg attagtctat
    28621 ttgattgttg cgctgatcat caaaaagatc ggttcagcat ggctggataa aatcttgcct
    28681 ccaatcgtcg tcggtccagt catcatggtt atcgggttgg gacttgcggc aaatgcagca
    28741 acaaatgcta tgtataatca gggcacgtat gatttcaagt atattgctgt agcgctgatc
    28801 acattaggat taacaatttt cttcaacatg tggctaagag gttttctcgg attgattccg
    28861 attttactag gtattattag cggatacatc gtagccttgc tgtttggaat cgtggatact
    28921 aagccaatcg tagacgctgc ctggtttgct gttcctaact ttgagattcc ctttgtacaa
    28981 tatgaaccaa agctatatct tggagcaatc acaacaatgg cacccatcgc ttttgtgacg
    29041 atgacagagc atatcggcca tcttatggta ttgaataaac taactaaacg taatttcttt
    29101 gaagaaccgg gtcttcataa gacgttgaca ggtgatggat tagcacaaat cgtggcagcc
    29161 tttgtcggag gtcctcctgt aacaagttac ggtgaaaaca ttggtgttct ggctatcaca
    29221 cgtgtccata gcgtgtttgt gatcggtgga gctgcagtat ttgcagtcat tttaggattc
    29281 gtaggaaaat taagcgcttt gattttaagt atccctggac cagtcatctc aggaatcagt
    29341 tttatcttat ttggagtaat tgccgcaagt ggaatgaaga ttttaatcga gaacaaaatc
    29401 gattttgata aaaagaaaaa tctgttgatt gcttcagtta tcttagtagt aggaattggc
    29461 ggactcgtct ttgaagtagg cacatttaca ttgtcggcaa tggcattagc aactgtactt
    29521 ggcatcattt taaatcttat cttaccagaa acttcacgaa gcgaagaaaa ctaaggagga
    29581 aacattatga tcatcaaatc agaacgtatc agcttaaagc atttattgac cgttgaggca
    29641 cttactgatc aagaagttat gggcttgatc cgcagagggc aggaattcaa gcaaggtgct
    29701 aattggactc cgcaaaagcg ccagtacttt gctacaaacc tctttttcga aaatagtact
    29761 cgcacacata aaagcttcga tgtagcggag aaaaaactag ggctagaagt gattgaattt
    29821 gaagcaagca caagctctgt ccaaaaaggg gaaacactat acgatacagt actgacgatg
    29881 tcagcattag gcgtagacgt agcggttatc cgtcatggtg atgagaacta ttatgacgaa
    29941 ctgatacaaa gtaaaacaat ccagtgttcg attatcaatg gaggagacgg aagcggacag
    30001 catccaaccc aatgcttgct tgatttgatg accatttatg aagaatttgg tcattttgaa
    30061 ggtctgaaag ttgccatcgt aggtgatatc actcactctc gcgtagctaa atccaatatg
    30121 cagatgttaa aacgtctagg cgcacaagta ttcttctcag gtcctagaga atggtacgac
    30181 gatgaattcg aagtgtacgg acattatatg ccattggatg aactactaga tcaagttgat
    30241 gtcatgatga tgcttcgggt gcaacacgaa cgccatgatg gaaaagaaag tttctcaaaa
    30301 gaaggctacc atcaggaaca tgggttaaca gttgagcgtg cgaagaagtt gcaaaaacat
    30361 gcaatcatta tgcacccagc accagttaac cgtgatgtag aattagctga ttcattagtg
    30421 gaaggattac agtcgcggat cgttcagcaa atgagcaatg gagtattcgt cagaatggca
    30481 atcttagaag cagtgctaaa tggaaaagcg taattatagg aggatgaaaa aatgaaaaca
    30541 ctcattaaaa acggtcagat caatacacga aaaaatatga cgacaccagc agaaatttgg
    30601 atagaagatg ggcgaatcaa agcaatcggt acaggattct cagaagccga atttgatgaa
    30661 gtgtttgatg caaagggaca attgatcaca cctggtttag tggacgtcca tgttcatttg
    30721 agagagccag gatttacata caaggagacg atcgaagctg ggactcgctc agctgctcgt
    30781 ggcggtttca ctactgtatg cgcgatgccg aatttaaatc ctgtacctga tacggcagaa
    30841 aagctgagac aagtatatga catcattaga aaagatgcag ttgtgaaggt attgcagtat
    30901 gcgccaatca cagaaaatct gcgaagtgag aaattagttg atcaagaagc actgattgaa
    30961 gaaggtgctt ttgctttcac aaatgacggt gtaggtgtcc aaacagctgg gacgatgtat
    31021 ctggctatga aagaagctgc aaaaaacaat aaagccctag tagcccatac agaagatgaa
    31081 tctttattat ttggcggcgt tatgcacgct ggcaagaagg cagaagaact tggtcttccc
    31141 gggatcttaa gcgtaaccga gtcttctcaa attgctagag atctgttgct agctgaagca
    31201 actggtgttc attaccatgt ttgccatgtt tctactaaag aaagtgtccg tgtaatcaga
    31261 gacgcaaaaa aagcaggaat ccacgtaaca gcagaagttt caccccatca tcttattttg
    31321 atcgacgaag atattcccga agatttcggc ttttggaaaa tgaacccgcc gctaagagga
    31381 cgggaggaca gagaagcttt gatcgaaggc ttgcttgacg gtacgatcga ttgcatcgct
    31441 acagaccatg ccccccatgg attagaagaa aaaagccaaa gtttcatgaa atcaccattt
    31501 ggtatcgtag gaagcgaaac agcgtttcaa ctgatctata ctcattttgt agaaactggt
    31561 cgattcacgt tggaacaagt gatcaattgg ttggcagtta aaccggctga gatttttggt
    31621 ttgaatgcag gaacgctaac ggttggtgcc cccgctgatg tagcagtttt tgatattaca
    31681 caaacttgca cgatcgataa agaagacttt ttatcaaaag gggagaatac accttttatc
    31741 ggctggaaag taaaaggcga aacacaaatg acttttgtca acggaaaact tgtgtggcag
    31801 aagggagaat aaaagtatgg aacgtttgct tatattagaa gatggaacag ttttcgaagg
    31861 aaaggctttt ggtgcagatg ctagtgtctt cggagaaatc gtttttacaa caagtatgac
    31921 tggttatcaa gaaactatca ctgatcaaag ttttaacggt caaatcatta catttaccta
    31981 tcctatggtg ggtaattatg gggtaaatag agatgattat gaatcgattt ctccaacatg
    32041 caaaggagta gtagtaaaag aacatgcacg tgtagcttca aactggcgaa accaaatgac
    32101 gctagattca tttttgaaac aaaaaggaat tcctggaata tcaggtatcg atacgcgcgc
    32161 ccttactcgc aaaatccgtg aagtcggaac gatgaaagct agtatagttg atgctggaga
    32221 ttccttcgaa catgcatttg atcagctgaa agcaaccgtt ctagcaacca atcaagtgca
    32281 gcaagtctca actaacaaac cttatccaag tccaggaaca ggtcggaaag tcattgtcat
    32341 tgacttcggc ttgaaacata gtattttacg agaattgagt aaaagaaact gtaacctcac
    32401 agtacttccc tataacacag atgccgagac gattttagcg ctatcaccag acggagtcat
    32461 gctgacgaat ggacctggtg atccaaaaga tgtgccagaa gcaatcgaaa tgatcaaaaa
    32521 aatccaagga aaagtaccga tttttggtat ttgtctcggt caccagttat ttgctttagc
    32581 caacggtgca gatacctata aaatgaaatt cggacatcga ggattaaatc acccggtacg
    32641 agaagtagcg accggaagaa ttgattttac ttctcaaaat catggctatg cagtcgatga
    32701 agccacgatt gatccagaaa aactcatcgt aactcatgta gaagtaaatg acggaacagt
    32761 agaaggagtc aaacacagag attatcccgc tttcagtgtg cagtttcatc cagatgctgc
    32821 ccctggtccg catgatgcac tacatttatt tgatgaattt atggaaatga tggacgcagg
    32881 aaaggagcag taaacagatg ccgaaacgta cagatatcaa gaaaattatg gtgattggat
    32941 ctggtccgat catcattggt caagccgcag aatttgacta cgcaggaaca caagcctgcc
    33001 ttgccttaaa agaagaagga tatgaagtgg ttttagtaaa ttctaatcct gcgacgatca
    33061 tgacggataa agaagtggca gatcaagtat atatcgaacc gatcacactt gaatttgtat
    33121 caaggattct tcgaaaagag cgtccagatg ctctccttcc aactttaggc ggacagacag
    33181 gcctcaatat ggcaatggag ctggcagcat caggtatttt agaagaattg aacatagaac
    33241 ttctaggaac aaagctttct gcgatcgatc aagcagaaga tcgtgatcta ttcaaacagt
    33301 tgatgaaaga attgaatcag ccaatccccg agtctgaaat cgtcaataca gtagaagaag
    33361 ctgtagattt tgcaaataaa atcggctatc ctgtcatcgt tcgtccagcc tttactttag
    33421 gcggaactgg tggaggtatg tgtgaaaatg aagaagaatt acgtatcgta tcagaaaatg
    33481 gattaagtct ttcccccgct acccaatgtt tgattgaacg aagtattgca ggttttaaag
    33541 aaattgaata tgaagtgatg agagattcgg ctgataatgc aatcgttgtc tgcaatatgg
    33601 aaaattttga cccggtgggt atccatacag gtgattctat cgtatttgcc cctagtcaaa
    33661 cattgtctga ccatgaatat caaatgcttc gtgatgcttc tctttcgatt attcgagcac
    33721 ttaagatcga gggaggctgt aatgtccaac tcgctcttga tccacatagt tttaattatt
    33781 atgtgattga agtcaatccg cgtgtttctc gttcatctgc gttagcaagt aaggcgactg
    33841 gctatccgat cgctaagcta gctgctaaaa tagcgcttgg attaacatta gacgaaatga
    33901 aaaatcctgt tacaggaacg acttttgcag aatttgaacc tgcattagat tatgttgtag
    33961 ctaaaattcc tcgctggccg tttgataagt ttgaaaacgg agaacggctt ttaggcacgc
    34021 agatgaaagc aactggtgaa gtgatggcta tcggtcggaa tatcgaagag tctttattga
    34081 aagctgtgcg ttctttagaa atcggtacac accatatcga acttcctgag ttggcagaca
    34141 tcacggacga tgacctaatc caaaaagtgg ttcgagcaca agatgatcgc ctgttttatg
    34201 tagctgaagc tattagaaga gggtacacca tagaagaatt agcggatttg acaaaaatcg
    34261 atttattctt tttagataaa ctgttgcata tcgtagaaat cgaacagcag ttgaaacagc
    34321 agccgttgga tgacaagata ttgaaaacag cgaaacaaaa cggttttaca gacaaaaaag
    34381 tggcggagct gtgggaaata aacgaagaag ccgttcgcca gatgagaaaa gaaaatgatt
    34441 tgattcctgt atataagatg gttgacactt gtgcagcgga attcgaatca aaaacacctt
    34501 atttttatag ttcctatgaa tatgaaaatg aaagttcacg atcagaaaag ccctcaattc
    34561 tagtactggg atctggtcct atccgtatcg gacaaggggt tgaatttgac tatgcgactg
    34621 tgcattctgt caaagcaatc cagcaggcag gatacgaagc aatcatcatg aacagcaatc
    34681 ctgaaacagt ttcgactgac ttttctattt cggataaatt atattttgag ccattgacct
    34741 tcgaagatgt gatgaatgtg atcgagctag aacagccgat aggagtaatc gttcaatttg
    34801 gtggtcagac agcaatcaac ttagccgaac ctttgactgc tgctggtgta aaaatcttag
    34861 ggacaacgat cgaagacttg gatcgtgcgg aaaatcgtga tttattcgag caagcgctga
    34921 aagagttgga tattcctcaa cctttagggg atactgctac aagtaaagaa gaagccgtgg
    34981 ttatcgcttc gagaattggt tatccagttc ttgttcgtcc aagctatgta ttaggcggac
    35041 gtgcgatgga aatcgttgaa aaccagcgag atttagaaga ttacatggaa catgctgtga
    35101 aagcatctcc agaacatcca gtactagtgg accgttactt gcttggtggt gaatgcgaag
    35161 tggatgcgat ttgtgacggt gaaacagtac tcatcccagg gatcatggag catattgagc
    35221 gtgctggtgt ccattcaggg gattcaatgg ctgtgtatcc acctcaaaca ttatctgaat
    35281 cgatcaagaa aacgatcgaa gattacacga tccgcttagc attaggtttg aattgtgtcg
    35341 ggatgatgaa tatccagttt gtcatccatg aaaatgaggt ttatgtgatc gaagtcaatc
    35401 ctcgagcaag tcggactgtt ccattcttaa gtaaggtgac aggaattcca atggcacaaa
    35461 ttgcgacgaa agctattttg ggagagaaac taaagacact tggttatgaa aacggacttt
    35521 atccagaaac aaaagaagtt catgttaaag cacctgtctt ttcttttacg aaattgcaga
    35581 aagttgatac ttacttaggg cctgaaatga aatcgactgg agaagtaatg ggatctgaca
    35641 gacaattaga caaagctttg tacaaggcat tcgaagcttc tggattacac ttgcctgaat
    35701 atggagccgt attatttacg attgcggacg aaacaaaaga agaagcacta gaattagcta
    35761 aacgttttac agaaattggc tatagtctga taggaacgaa acatacagct gcttatttcg
    35821 aaaaaaatgg tctggtcgtt gaaacagtag cgaaaatttc tgaggaagca gcagaaaaaa
    35881 atgtagtcga cttaataaga gatggtaaaa cacaagtggt tgtcaatacg attgataaag
    35941 atcggggaaa tgcttctaaa gacggtttca tcatccgaag agaagcagtt gaacatggta
    36001 ttccattgtt tacttcttta gacacagcag atgcgatcgt tcgagtgatg gaatcccgtg
    36061 ctttttcaac taaccctatt taacggcgag cacatgttaa gacaaaaaga cgaaaaaccg
    36121 ttgcaggagg ggacagatga aacaagaaat gatggaaatc gttcagcaaa aacagctggc
    36181 accaaagatt tttgaaatga cattgaaagg tgatctagta aaagaaatgc agcaaccagg
    36241 acagttcttg catattctcg tgccgcgtgc agacttgcta ttacgccgac cgattagctt
    36301 gaatcatatc gaccacgaaa caaatacttg ccgtatcatt tatcgggtgg aaggtgaggg
    36361 gactagagtc ttctctactc tttctgccgg agaccattta gatgtcatgg gtcctttagg
    36421 caatggtttt gatttgtcca atcttcatac aggagacgaa gtatttataa tcggtggagg
    36481 aatcggtgtc cctcctctat atgagttatc aaaacagtta gtcgaaaaag gaattaagcc
    36541 aacgcatttt ttaggttttg ccacacatga agtcgtttat tatgaaaaag aatttaatcg
    36601 tctaggagaa acaagaatcg ctactgacga tggaacatac ggtatgcacg gaaatgtcgg
    36661 taatttattg ttaggaacga agacggaacc tacagctgtt tttgcatgtg gttcaaacgg
    36721 gttattgaag acagtggaac agctgttttc ttcgcatcaa aatgtccagt tatcattaga
    36781 atcccgcatg gcatgtggga taggggcttg ctatgcttgc gtttgtcata cgccggaaga
    36841 tgaaacagga acaaaaagtg tgaaagtttg tgacgaagga ccgattttta aaataggaga
    36901 ggtaattata tgaatgagaa tcctttagcg gtcaaacttc ctggcctaga attaaaaaat
    36961 cctatcatgc cggcaagcgg ctgtttcggt tttggcaaag aatacggaaa atactatgat
    37021 ttgaatcagc ttggatcgat catggtcaag gcaacgactc caaatgcccg ctttggcaat
    37081 cccacgccaa gagtggcgga aacaccatct ggcatgttga atgcaattgg tttgcaaaat
    37141 cctggtctag acgttgttat gcataaactt cttccagaat tagaggagta caatgagtta
    37201 cccatcatcg caaatgttgc tggtgcttgt gaagaagact atgtagaagt ttgtagcaaa
    37261 attggcgaag caccaaatgt gaaagcaatc gagctgaaca tttcttgccc aaatgtcaaa
    37321 catggcggaa ttgcttttgg aacagattct gatgttgctt ttcaattaac acaagcagta
    37381 aagaaagttt cttctgttcc tgtctatgtc aaattgtccc caaatgtaac agacatcgtt
    37441 ccaatcgctc aggcaatcga agctggaggg gcagatgggt ttacgatgat caatactctt
    37501 cttggtatgc ggattgacct taagacaaga aaaccgattt tagccaatca aacaggtgga
    37561 ctctccggac cagcaatcaa gcctgtcgct attcgtttga ttcaccaagt agcaagtata
    37621 tccagccttc caatcattgg gatgggcggc gtgcagacag tggatgatgt tcttgagatg
    37681 tttatggctg gagcaagtgc tgtagctata gggaccgcga atttcaccga tccgtatatc
    37741 tgtcctaaac taattaaaga gctccctgtg cgaatgagcg aactaggcat cgaatcgctg
    37801 gaaagattaa tcaaagaagt gagagaggaa cgtgaacgat gaatcaacta gaccaacgac
    37861 caattattgc attagatttt tcaactaggc aagaggtaga agactttctt cgatttttcc
    37921 cgaaagaaga aaaattgttt gtgaaaatcg gaatggaatt gttctaccaa gaaggacctg
    37981 aaatcgtacg ttatctaaaa gaggctggtc ataatgtatt tttagatctg aaacttcacg
    38041 atattccgaa tacggtcgaa aaagcaatgc ggggattggc aaagcttggt gttgatctca
    38101 cctgtgttca tgccgctggc ggtattcgta tgatggaggc ggcaatgcga ggattagaag
    38161 aggggactcc agaaggtgga aaacgtccgc tacttctagc tatcactcag cttacttcta
    38221 caagtgaaga agaaatgcat gccgatcaac taatcgaagt ttctttagaa aaaagtgtga
    38281 tccattatgc tagctgtgcc aaaaaagcag gattagatgg tgtggtttct tctgcttggg
    38341 aagtagaagc gatcaaagaa atggcaggag acgaatttgt ttgcttaact ccgggtataa
    38401 gaccagaagg aacagtcgca ggagatcaga caagagtagt cacaccttct caggcaaaaa
    38461 agatcggctc aacttttatc gttataggtc gaccaatcac tcagtcaact aatccttata
    38521 aagcatatca aacgattcaa acagaatgga gctaacctaa aatgaatgtt gaacaaagta
    38581 tcgcaaaaga cttattagaa attgaagcag tatttttaaa tccaagtaat ccttttacat
    38641 gggcaagtgg aatcaaaagc ccaatttact gtgataaccg aatcacgatg agctatccaa
    38701 aagtccgaaa agagatcgca aaaggattag caagcaaaat caaagaagct taccctgaag
    38761 tacaagtgat tgctggaact gcaacagcag gaatccctca tgccgcatgg gtagcggaaa
    38821 tactggattt gccaatggtc tatattcgaa gtaaggcgaa agatcatggg aaaggtaacc
    38881 aaatcgaagg acgtatattt gaaggtcaga agatggttgt gatcgaggat ttgatttcta
    38941 caggcggaag tgtcttggaa gcagctgaag cagcaaaaag agaaggtgcg gatatccttg
    39001 gtgttgcggc tatctttacg tatgagttgc caaaaggaaa agcaaatttc gaaaaagccg
    39061 aaatccctct tatgacgttg accaattatt ctgtattgat tgaagcagct ttagaagatc
    39121 gttatatcga tgagcaagaa ttaactctgc taaaagaatg gaaaaaagat cctgaaaatt
    39181 ggcagattta agcgcgcttg atgaagatag agaaatccga tttgtgtctc cagaatcatc
    39241 aattggaata gcaaaaatcc aaaaactgat tgcgagaagc atcttttcat caggtatgaa
    39301 aagaaacttc tatcgtgatc agtttttgat ttttttaaaa ttcatttttc taagactggt
    39361 tagcagaaag aagagaataa tctcttctct tttttctatt atatatagat tttctctatt
    39421 ttttggtaag ggagctgttt caaaaatggt aaagagcgga aatgttgcga atatcagtta
    39481 tttaatgata tgatattcgg aaaaagaaat ctcaaaggga ggtaactttt atggggttga
    39541 atgaatttat tttaggattg aacaatttag agacgatcac aagggcacct ggatttttta
    39601 aatatacaga gcatacagtt gcagcacatt cgtatcgtgt agcatctatt gcgcaagttc
    39661 taggagacat tgaagaagcg aatggacaac cgatcgattg gaaactgctc tatgaaaaat
    39721 cattgaatca tgactacaca gagcgtttta ttggtgatat caaaacgccg gtgaaatacg
    39781 caagcaaaga gttaagaggg atgctgcaaa cagttgaaga aaagatgacg gacgaattca
    39841 tcaaccaaga gattccagct gagttccaag aagtttatcg ccgtcggttg ttcgaaggaa
    39901 aagatgaaac cgtagaagga gaactattag ccatttcaga taaggttgac cttctttatg
    39961 aatcttttga tgaaatcatc aaaaataacc cggaaaaagt ttataaggag atgttcattg
    40021 aggcagtgac tacgattaaa agctttgaac atcggccttc tgttcagtat ttctttaaag
    40081 agatatttcc ggaactattg aaccaggaat tttatggaaa agaggcgttt ttagaaaccg
    40141 tctcaacgat tgtaaagaaa gaagaaaaat aaaaatgata tgagatgcag ggggaagtat
    40201 agttgaaaaa gaatatggat gtcgaatggg gctattctgg agacaaaggt ccggaaaatt
    40261 gggcgagttt atgtgattgg tttgcgagag gtgcggaatt tccattgcag tcgcctattc
    40321 atttgaccaa gggggaagaa accaaaatag aaggagacac gctttccttt cattatcaaa
    40381 agcaacggtt tactgacaag gaattcaaaa acacgattca tttagtacct tttgaccaac
    40441 tcagttatgt agagttcaag aaagaacgct attatttgac agatattcat ttccacttgc
    40501 cttctgaaca tatcatcaac ggaaaacagg aagatattga atttcatttt gttcatatga
    40561 acagcaaaaa agagaatcta gttgtgggtg tcatgtacca gctaatggta caggaaggtt
    40621 ggctgtataa tcaagaaaat ggggaaagtt ggaacttaga aaaacatgag cattgggtaa
    40681 atccggatgt gttctttccg gagcaaaaaa gccatttcca ttatattggc tcattgacaa
    40741 ctccgcctac cagcgggcca atccaatggt ttgtaatgga tcatgtagga aaactgaacc
    40801 aagagtttct tctccccttc gatggtcagt atgctcgacc gaacaaccga ccaatccagc
    40861 ccttgaatgg aagagaaatt tattatttcg aggagtttga gcaatgaata ttcagcagat
    40921 gaaatacgtg gtcgctgtag caaacaatgg tagtttcaga gaagcggcaa agaaaatgtt
    40981 tgtctcccag ccaagtcttt cagctggtat caaagaatta gaaaccgagt tagggatcac
    41041 gctgtttact cgaacgaatc gaggggcata tttaacagaa gaagggcaag acttcttaaa
    41101 tcgtgccgag aaaatattgg tccagcttga tacattagaa actcactatc taacgagtga
    41161 aaagagagac aatttttcga tcgctgccca gcattatgat ttcttaggtc ctttgaccgc
    41221 acagctactc gaggaattca aagacgagat caaacaattt cggatcatgg agacgacaac
    41281 agcgagagtg atcgaagaag tcaaagagca gcacagtgag atcggcatta tttatatgaa
    41341 tgagcataat caagctggta tcagaagata tttacaacaa ggagagctaa gtggccgcag
    41401 cattggaaaa ttcaaaacgc atattttttt aaggcaagga catccattag ctgaacacgc
    41461 agagatcacc aaagaagaat tgttatctta tcctcaagtt cgttttacac aggatggaaa
    41521 taatttcccg tatttttatg aagaccttat cgagatccct gatcaagaaa cagtgattta
    41581 tacgagtgat cgaggtactt tgatgaatat cgttcttgaa actgatgctt acgcttcagg
    41641 atctggtatt gtgattggag ggattcgcga gcacttgcgg ttaatccctt tggcagaagg
    41701 cgaactaaat gaattttata tcatttattc ggcgaaacgt ccgctcagtg aaatcgctca
    41761 aagatttatc aaagagctta ctcggttact ggaccagcag agctaagaaa agcagatgag
    41821 aacgctgttt attgaacacc gttgatcaaa aaagaggggt tgtgacagaa ttttgtcaca
    41881 actcctcttt ttgtagcaaa caatttataa ctaattgctg ttgtgggaaa gtacgcaaat
    41941 atgattctag aaacactcat tgattacctg ttttgtttca tagctgtaat tttttcttct
    42001 tctggtgtca cgataatcgt cttttggttt tcataaataa cataaccagg cttggcgcca
    42061 tttggttttc ggatatgctt tacctgtaca agatcaaccg gcacttgggc agagtatcgg
    42121 tattttgaaa aataggcagc taactcggca gcttctgtaa ttgtttcatc tgagggcttg
    42181 tcacttttaa tgatgacgtg cgaaccgggt atattttttg catgaagcca atagtcggtt
    42241 tttttagctg tcttcattgt cagctggtca ttttgaagat tgtttttacc aacaagaatg
    42301 agcgttccgt cagaagaaaa gtattgatca ggctgagatg gtttcttacg tttttgtttt
    42361 tttaagttct tctttttcag gtatccttct gaagtcaatt cttctttaat tgcttcgata
    42421 tccattgggc cggcaatttc cagttgagat aagacagatt caagatattg gatttcatct
    42481 ttggcttctt ggatttgttc gccaatcagc ttaacagcgt tcttcagctt ttggtatcga
    42541 tggaaatatt tctgtgcatt ttgatttggt gtcaatgccg gatctagtgc tattttgatt
    42601 ggccgatctt cttcataata attaggtaaa acaacttctt ttgcgccgcg tggtacttgt
    42661 gtcagaaaag tagtaagtag ttcgccattt ctacggtaat tctcagcgtt ttcggattct
    42721 ttgagtgttt gttcacgttt tttcaattta tttttatttc gttttagttc attttcgatt
    42781 tttcgaatca gttctccgcc ttgttgtttt gcccgatctt tctctgcttt ttcgtgataa
    42841 tagctatcta ataattgact gagtgttgga taagctgtta cagcagatgc ctgttcggac
    42901 aatacctgat aagcaatcgg tgtgaaaaaa tctttatttt ccgtttcgta aaaagtagga
    42961 ataggctgat ggctgatggc tgagaaaaat tcgtcccata caaccatctt ttcattagga
    43021 cgttccagta atcttttggt cagctcttga gcgatatcga aaccgattcc ctgaaactga
    43081 cgttggattg cttttggatc tagttcagtt tgggaaagcc gctgaaagat tttttctttc
    43141 tcggagctaa atgggttcaa gacctcttgt tttggcggag caacatattc tacaccagga
    43201 agcaaagaac gataagtgtt ttgagagctt ccaatgtgtt tgatcgcatc cagtattttt
    43261 ccagtttctc gattaactaa gacgatcgta ctatgacgtc ccattaattc aacgatcaat
    43321 atgatatttt gtagatcacc caactcgttt cgtttagcaa agtggaaatg gatcactcga
    43381 tcattttcga tttgttcgat gtcttctaaa atagcgccat ccaaatattt tcgaagcatc
    43441 atcacgaagt taggcggatt atcaggattc tgataatcga tttgggtaat ctgtacacga
    43501 gcataacttg ggtgcgcaga taataataat cgatggtttt tgccgcgtga acgaatcacc
    43561 agcacgattt cattttcata aggctgatgg attttcgaga tccggccaga tagtaacgtt
    43621 tcacgcaatt cgttgaccat cgcgtgggta aatacaccat caaaggacat ggttcattcc
    43681 tcatttcttt tcataagtat attcattata acgaaaaaaa gaagaaaaac caatttggcc
    43741 gaatagtaaa gcaaaagtct agaaaaatct tggactaatt acataaaaaa cagtgtttct
    43801 atcgttgaaa tccaaatttt taggta
//
LOCUS       DAXLPC010000013        42894 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.013, whole genome shotgun sequence.
ACCESSION   DAXLPC010000013 DAXLPC010000000
VERSION     DAXLPC010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.013"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            109..3387
                     /locus_tag="ACF3UE_000680"
     CDS             109..3387
                     /locus_tag="ACF3UE_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HFD3634136.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(3928..5835)
                     /locus_tag="ACF3UE_000681"
     CDS             complement(3928..5835)
                     /locus_tag="ACF3UE_000681"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFD3634137.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            5965..6840
                     /locus_tag="ACF3UE_000682"
     CDS             5965..6840
                     /locus_tag="ACF3UE_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFD3634138.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            6920..7894
                     /locus_tag="ACF3UE_000683"
     CDS             6920..7894
                     /locus_tag="ACF3UE_000683"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFD3634139.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            8074..9219
                     /locus_tag="ACF3UE_000684"
     CDS             8074..9219
                     /locus_tag="ACF3UE_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFD3634140.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            9356..9700
                     /locus_tag="ACF3UE_000685"
     CDS             9356..9700
                     /locus_tag="ACF3UE_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFD3634141.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            9971..11257
                     /gene="efmA"
                     /locus_tag="ACF3UE_000686"
     CDS             9971..11257
                     /gene="efmA"
                     /locus_tag="ACF3UE_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HFD3634142.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(11395..11994)
                     /locus_tag="ACF3UE_000687"
     CDS             complement(11395..11994)
                     /locus_tag="ACF3UE_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFD3634143.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            12398..13519
                     /gene="mnmA"
                     /locus_tag="ACF3UE_000688"
     CDS             12398..13519
                     /gene="mnmA"
                     /locus_tag="ACF3UE_000688"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFD3634144.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLIYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            13765..15186
                     /gene="arcD"
                     /locus_tag="ACF3UE_000689"
     CDS             13765..15186
                     /gene="arcD"
                     /locus_tag="ACF3UE_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFD3634145.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            15200..16318
                     /locus_tag="ACF3UE_000690"
     CDS             15200..16318
                     /locus_tag="ACF3UE_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFD3634146.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(16378..17670)
                     /locus_tag="ACF3UE_000691"
     CDS             complement(16378..17670)
                     /locus_tag="ACF3UE_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFD3634147.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            17820..18380
                     /locus_tag="ACF3UE_000692"
     CDS             17820..18380
                     /locus_tag="ACF3UE_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3634148.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            18509..18886
                     /locus_tag="ACF3UE_000693"
     CDS             18509..18886
                     /locus_tag="ACF3UE_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFD3634149.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            18819..20891
                     /locus_tag="ACF3UE_000694"
     CDS             18819..20891
                     /locus_tag="ACF3UE_000694"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFD3634150.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(21102..22049)
                     /locus_tag="ACF3UE_000695"
     CDS             complement(21102..22049)
                     /locus_tag="ACF3UE_000695"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3634151.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            22295..22759
                     /locus_tag="ACF3UE_000696"
     CDS             22295..22759
                     /locus_tag="ACF3UE_000696"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFD3634152.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(22821..23864)
                     /locus_tag="ACF3UE_000697"
     CDS             complement(22821..23864)
                     /locus_tag="ACF3UE_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFD3634153.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(24241..25206)
                     /locus_tag="ACF3UE_000698"
     CDS             complement(24241..25206)
                     /locus_tag="ACF3UE_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFD3634154.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            25440..26285
                     /locus_tag="ACF3UE_000699"
     CDS             25440..26285
                     /locus_tag="ACF3UE_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3634155.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            26476..27663
                     /locus_tag="ACF3UE_000700"
     CDS             26476..27663
                     /locus_tag="ACF3UE_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFD3634156.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            27669..28025
                     /locus_tag="ACF3UE_000701"
     CDS             27669..28025
                     /locus_tag="ACF3UE_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFD3634157.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            28027..28365
                     /locus_tag="ACF3UE_000702"
     CDS             28027..28365
                     /locus_tag="ACF3UE_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFD3634158.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    28441..28697
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            28760..29794
                     /locus_tag="ACF3UE_000703"
     CDS             28760..29794
                     /locus_tag="ACF3UE_000703"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFD3634159.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            29787..30473
                     /locus_tag="ACF3UE_000704"
     CDS             29787..30473
                     /locus_tag="ACF3UE_000704"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFD3634160.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            30497..31345
                     /locus_tag="ACF3UE_000705"
     CDS             30497..31345
                     /locus_tag="ACF3UE_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFD3634161.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            31542..32315
                     /gene="sufC"
                     /locus_tag="ACF3UE_000706"
     CDS             31542..32315
                     /gene="sufC"
                     /locus_tag="ACF3UE_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFD3634162.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            32328..33614
                     /gene="sufD"
                     /locus_tag="ACF3UE_000707"
     CDS             32328..33614
                     /gene="sufD"
                     /locus_tag="ACF3UE_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFD3634163.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            33611..34846
                     /locus_tag="ACF3UE_000708"
     CDS             33611..34846
                     /locus_tag="ACF3UE_000708"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFD3634164.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            34833..35303
                     /gene="sufU"
                     /locus_tag="ACF3UE_000709"
     CDS             34833..35303
                     /gene="sufU"
                     /locus_tag="ACF3UE_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFD3634165.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            35308..36699
                     /gene="sufB"
                     /locus_tag="ACF3UE_000710"
     CDS             35308..36699
                     /gene="sufB"
                     /locus_tag="ACF3UE_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFD3634166.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKAVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(36794..37936)
                     /locus_tag="ACF3UE_000711"
     CDS             complement(36794..37936)
                     /locus_tag="ACF3UE_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3634167.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(37975..38709)
                     /locus_tag="ACF3UE_000712"
     CDS             complement(37975..38709)
                     /locus_tag="ACF3UE_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3634168.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIIEEFDNNILLLTSSIEEQLEEMIDEGIHSQVEDMNYPEEAVNEIIDN
                     INKLKQTISSIGKKYTKKKMKGGDTI"
     gene            38944..39219
                     /locus_tag="ACF3UE_000713"
     CDS             38944..39219
                     /locus_tag="ACF3UE_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3634169.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMEQYKG"
     gene            39317..41314
                     /locus_tag="ACF3UE_000714"
     CDS             39317..41314
                     /locus_tag="ACF3UE_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634170.1"
                     /translation="METPMINIPINVDKERLLEKPVIEDEKKRIRKRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNKSEEFLETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKALSINLVHNSAFAIQKSIRYSENLEKFKIVFLLKEAITDYSKMIAVYEYLKKI
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHDDHNPSASIFTSKTGHSIFYCHSSNCGISENFIGVVMLILEKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMEDKLFRTINNYLEEMRRVYDALLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKWNKLLSFMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLKKVHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNFRSELSKEKQLILDEAHEVLQDLSWQGTYLMTEKELINTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELIASGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(41390..41725)
                     /locus_tag="ACF3UE_000715"
     CDS             complement(41390..41725)
                     /locus_tag="ACF3UE_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3634171.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            41851..42066
                     /locus_tag="ACF3UE_000716"
     CDS             41851..42066
                     /locus_tag="ACF3UE_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3634172.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            42103..42465
                     /locus_tag="ACF3UE_000717"
     CDS             42103..42465
                     /locus_tag="ACF3UE_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFD3634173.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADEVKKSTEQTFS
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            42511..42837
                     /locus_tag="ACF3UE_000718"
     CDS             42511..42837
                     /locus_tag="ACF3UE_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634174.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
BASE COUNT        14055 a         7675 c         8991 g        12173 t
ORIGIN      
        1 tctttttata aaatacactt attataattt tgttttttat tgacagtaaa aataaattag
       61 gtaatacttt aagtaaacgc tttctaattt gttacgggag gaatacactt gttaaaaaaa
      121 cgtataaaat acagtgcgct aatgatgaat ctccttatgc tcagtacccc ggttttaatt
      181 tctgtcgttg aagttgctgc taacgaacaa cagtctgtga acgaagaaaa tgcacacgtg
      241 aacattgaag ggatgtcaac aatggaggaa ataccaagaa ctagtgaaga tatggatacg
      301 gaagaaggaa atgatcctat gatgaaagaa tcagaaaatg aaaagacaaa aaagcaatct
      361 gaagaagcaa atgaagagtg gaaaggggtt gttttcggag aaagcacaag tgctagtagg
      421 tatgccattg aaccattaga agacggcgtg cggctctctt ccacgaataa cggcggaaaa
      481 ttccagtcaa gcggatcaga tggaatgacc tattattatc aagcaatccc caaagacatc
      541 aactttagga tgcgggcgac gatcgaaata gaatcttgga cctatacgaa tgcccaagaa
      601 ggatttgctt taatggtaag agacgcagta ccaaaaaatc atttgtttgg gcaggcattt
      661 tattcaaatt catttgccat actaggcagt cggatcgaat atgtctggga ctcggataga
      721 caagaagtgg tcaacacgag cggcagcaaa tatacgatgc gacttggatt ggggacacgg
      781 gcaatcacag gaatatcatc tgaagatccg caagctgcgc cagctcctgg gagtgtctca
      841 gtggaaacaa cacctttaga gacttcagca gggttcttgg aaaaagaaac aggttcttat
      901 aatatattcg gaaacggtca tgggaatctg tttccggcca cgaactcgat tactaaactg
      961 gacgtagaga tgaaaaaaac gaatactggt ttagaggcat attattacga tcctgaaaca
     1021 ggagaagaaa tggcttctga catcatgtat gactgggaaa aattatacgc ttcagatgaa
     1081 tcggttattt atgcaggatt tgctgcagca aggaatatga cgatcaaggt agaaggaatc
     1141 gaagttgctt actcagatcc tgcgacagat cctcctgggc aagaaagacc tactcgcttg
     1201 attgatccga tttacactgt gacctctagt aatcattcag gaaaccaaga tcatactatg
     1261 tcctttagag caaatgctga cggattattg acaattaaaa ataaagcaac aggagaggtg
     1321 cttaagaacg caaaaaactt ggctatcact gcgaatcggg aatttgatta tcagacaaaa
     1381 ctgatggaag gaacgaacga atttactttc agttttacgc cagataaaaa ctatccgcca
     1441 gaagaatacg tagagatgac tagttatgaa acaaaagaga ttcttcatac agtggactac
     1501 cgtaaaccta aatattcgac agtttatgta acaccagaag ggtcagatgc aggaaacgga
     1561 agcagacaaa atccattatc tctgacacaa gcattgagat acgcatatgc tgggcagaca
     1621 atcgtcatgg cgcctggaac ttattccttc gaaagaggat tgacgattcc aaaaggcgtt
     1681 aacgggacaa gagaaaaccc gattcagttg attgcagaga aaaatccaga aaacaagcgt
     1741 cctgtacttg attttaaagg aactggaaat gggatgacac tgttcagtca ctactggggt
     1801 ttacgagggt ttgacattac aaatagtgca gctatgcaaa aaggattaca gatttctgga
     1861 aatcataatt tgatcgaaga gattcatgct tatcggaatg gaaatacagg aatccaaatc
     1921 agcggtagct caaatgatcc tttcgaagca tggcccgcgc ataacttagt caagaactgt
     1981 acatcttttg aaaatgccga tccaggattt gaagatgccg atggatttgc ggccaaactg
     2041 acaataggag aaggaaatgt atttgacggt tgtatcgcgt atcataatgc agatgacggt
     2101 tgggaccttt ttgctaaaaa tgaaacaggt tcgatcggaa aagtaatcat caaaaactca
     2161 gttgcttatc gaaacggctg ggtaccagga attgagggag aaggtaacgg taatggattc
     2221 aaaatgggcg gttcttcttt aacgggccct catgaattga tcaatagttt gtctttcgaa
     2281 aatcttgcga aaggaatcga ttccaatagc ggaacagata ttatcgtcaa tagcagtaca
     2341 agttttaata acggttcata taatgtggct ctttatacct cttcagcagg aaacacagac
     2401 taccatgctt ctggtatctt atctttccga acagagaatc ttgagatgag agagcagatc
     2461 cgcccattga atcaaaacga agatcaaatc taccactcgt tgaactacta ttggaatgaa
     2521 cgagagaaac aatcagaaaa tactcttgga cataccatat caaaagattg gatcgagtct
     2581 ctaaatacat gttcgaaaga aggtcagcag cctgttacgc gctatgaaaa tggaagtatc
     2641 catgttcatg gactgatgca gattaaaccg gggaatcgtc aaacagaaaa ggaaagagtg
     2701 gatggtcttc cattatctgt aggtgctatt tttgacggag aaacctcacc gtcttcggaa
     2761 tatccagagt atgcaatcgt acaagaacca aatcagacaa aaccaaatga acaaaataat
     2821 ccgattatta tacaagaagc aaatggtgtg gcggagaatg cagaaggaaa tatcattgaa
     2881 ctgaagcctt ttacagtttt tgtgtcaact ttcacaccaa atcaaggaac gcctgtcttt
     2941 gaagatatgc gttatttccc agaaaagatc caaatcgttg aaacacagtc aagtgctcaa
     3001 ttttctaatc ataccgctat tttttcagca ccttcaaaag gagaatatac gctagaagtc
     3061 acttatcgtt cggaaatatt tgatggggaa aaatggtctg ctcatacaga atctgttacc
     3121 cagcaaaaag cgatcactgt gcgagaaact gccgatgtgc ccccgggaaa tgacaaacca
     3181 gaaagagaaa atccaggaaa tgaatcacca aatggaaaac caaatggaaa accttctcat
     3241 ccggatagga cagcaaaaga aagtgaaaaa aatggcactc aaggactccc aaaaacggga
     3301 gaatttaata acccgttgct agcattagct ggaggaattt tgttaatcgg tgtagttgtt
     3361 tatgtcatga aacagcgaaa aaaataagtg gaatttctcc ttttatgatg taaaacaatt
     3421 gactgaggaa agtaaaaata gaaggaaatg agaccaatag atgtctcact tccttctatc
     3481 tttttataga tgaggttctc cttgctgctt ttgattggct gttcttatta cttgatgcag
     3541 gacagctttt tcacaatctc tccactaaac ggtgttcaat cagctgaccc tcggtattag
     3601 ctcaacaaac ggcaaaatat gaggaactat ttttccgttt ttttctctaa tactcaggtc
     3661 aggacgctga tttcacaacc tctcgataaa cggtgttcaa aagccagttt ctcggtagta
     3721 agtcaaattt atgcaaaaat gtggaaagcc attttcacaa aatttttctt actacttgaa
     3781 actaagcagc tttttcacaa cctctaatac atggtattcc agaagtaact tcttcgaaaa
     3841 ataagccgaa atgtcacaaa aatttgagaa gcgattttcc caaattcctt cttatttctt
     3901 gaagctgacc acttctggca caacctctta ccagattcgc actctttttt ctggcgctag
     3961 atacatagcg tcttgttccg tgataccaaa tgtttcatag aattcgtcaa ggttttttgg
     4021 ttgcacgttt gctcggagtt tagcaggggc atggacatcg atttgcagta aaagttgttg
     4081 gtattctttt tttgcttttg tacgccaaat cgttgcccaa ttgacaaaga attcctcgat
     4141 agaaagatct gattccgttt ttgctgcttc caatgcacag cttagaccgc ctgcatcagc
     4201 aatattttcc gaaacggtta attttccgtt tacttttccg tcagcaaaag gcagaccatc
     4261 gaattcttcg atcattgctt gtgctttgtt ttgaaattgt gtaagatctt cttctgtcca
     4321 ccagttgttc aagttgccat attcgtcaaa taaagcgccg ttattatcaa atgcatggga
     4381 aatctcatga gcgataacag ctccgattcc accataatta gcagagcttg attgttctag
     4441 actgtaaaat ggtgcttgaa ggatcgctgc cggaaagacg atcacattcc gaaatggatg
     4501 ataataagca ttgaccgtgt cagcactcat ttcccattct gaacgatcca ctggtttgtt
     4561 ccatttgctg aaacgatctt ttaatgtgag tttgctgaaa acaagagtat ttgaaagcaa
     4621 agtaccaccc tgatctgcag gtactgtttt gaactggtcg aataatgctg ggatcttatc
     4681 ggggtagcct acttggatac ctaagttatt taattttatg acggcttttt cttttgttgc
     4741 atccccaagc cagtcatttt cttctagacg ttttttataa acggcgatca tttttttcac
     4801 catttgttct acgtcttttt tagcagcttc gccaaaatat ttttttccgt agtaatcgcc
     4861 aactacttga tcgaattgtc cagaggcaag gtaatacgct gcttttttct gaggcattgc
     4921 ttcgtctgtt ccagacaata cgcgagaata gattccgctg acttggcgga attcttctga
     4981 tagataacca ctaagagaac gtactgtttt aatgatcatc cagcttttga ataacggaaa
     5041 atgagcttct gtcaggatgt cattcaaatg atcgaagtac actggatcag ttacgatcac
     5101 tttatctgga gttgtcccaa tcaaacccgt gacaagtttt ttcaagtcca gtttatctgt
     5161 gtatttaata aatgtatcaa aagattgcgg attatacatt ttgctgtaat ctgcgttttc
     5221 ttctgcactt tttacatgag gagcaatcaa tttatcaaat tgcactgctt gttccgtgat
     5281 tgcttctgcc tgactttttt ctttgccggc aagctctaat aactgaacag ccatatcaaa
     5341 gaaaacgcct attagttgtg caccgttggg atggtctgat gcataatacg tcttatctgg
     5401 aaggaataaa gaaggcggat aagcaaagaa ggcgttcgtt tgcgcattct tcatatctgc
     5461 atctacatcc agattaaatg gcaatggtaa tgtatccaac agccattctg gaaattgctt
     5521 attcaattcg tcgaaagact gcaatgattc aactttttcg attataggtt gaagcggttg
     5581 agcatgcaac tcatttcttc ggtcataatc gtttgccagt tgataatatg caaggaaatg
     5641 tttcattttt tctgaagaca ctttttctgg atgggcaagc agatcgtctg tttctcccat
     5701 caaaagttgg tcgatcccgt caactaaatc ttggaaaccg cctgtagctg gtttatctgc
     5761 agggattttt gctgtttttt gccattcttc attgactgct tcatagaaat cttgtttcaa
     5821 tcgttctttg ttcattcatc gatcgctcct tttttgtttc gtgtgcccat tatcttacaa
     5881 aatgaaggaa ttaacaaata gaacataaaa aattgaaaat tcgaacaatc aaactgattt
     5941 gtttttttca atccttcact tataatgaaa aaaaggaggc gatcccaact gaatcaagta
     6001 gtggataaac ctttatattt caaagtagat aaaaaaatta aaaaattagc cagcactcag
     6061 cagctgcagt caagaaaaag taaattgctt tttttagctc tggtttttga agatcaaagt
     6121 tatgtgatta tcgatcaatc aggacatccg gtagaatatt ctccagcaaa atatacttat
     6181 caagagggtc tttcttgtaa aaaatggaag ctgatcaatg aagagccaat cgagttatct
     6241 agatggatca acagaaaaga agatattccc gttttgatcg aagaaaaaag gtcaggaaag
     6301 gaactcgcaa attgctgggt gggattgcca gaagaacgtt ttttgaggta taagaaatgg
     6361 gctaccccct caggctatct ttgtggtact tacgcggcag cagttctcct tgcctattat
     6421 caagactatc gtaaggggtg gatgcttcca aatgagattc gcaagaaaaa tacggctgat
     6481 tcgttggttt tgacgaaggc attgcgtagc cagatccaac cactaggact tcctacgatt
     6541 ccttttcagg ttagtacagg gatttctagt tttttaaaga agaatggcaa tcatgagcgt
     6601 gcacgagcaa ctcttctagg ttcatggcag cgagctacaa aacgtatacg tgaaggcaaa
     6661 cctgtgatga ttggtatttt gaaagtactt ggcagtacat atggcaatca ttgggtgaca
     6721 gcgtacgctt attttgaaac tgaaacagga gaacgttatt acaaagtaca cgacaactgg
     6781 ggcgattatc ataaagtcat tcctgccagt tggagtaacg gaacagtttc acttccttaa
     6841 gaatttgctg aaattaacag aaaatcttgg aaaaatatgt taaactatcg aagaatagag
     6901 aagttttggg gaggactaca tgagtaataa gtatcaggat gacacgttga agatttttag
     6961 tttgaatggc aaccgtccat tagctgaaaa aatcgcgaaa gtgttcggaa cagaattagg
     7021 taaaagcgtc gtgaagcaat ttagtgatgg cgagatttcc atcaatatcg aagaaagtat
     7081 tcgaggggat catgtgtata tcgttcaatc aacgaatgca cctgtcaatg attactatat
     7141 ggaactactg atcatgatcg atgcaatgaa gcgagcaagt gcgaaaacga tcaatgtcgt
     7201 attgccttac tatgggtatg ctaggcaaga ccgcacggcg aaacctcatg aaccgatcac
     7261 tgcgaaattg atcgctaact tgatcgaaga agcaggggca actcgagtac tgactttaga
     7321 tctgcacacg gttcaagtac aaggattctt tgatattcct gtagataatt tatttacgat
     7381 gccgttgttt gctcattatt accgtcaatt aggtctgacg ggagatgaca tcgtagttgt
     7441 ttcgccaaaa aacagcggtg ttcagcgtgc acgtagtctt tcagaatatt tgaacagcac
     7501 attagccatc gtagatcatg cagatgatgc ttcaactgag ggtggttatg tgatcggtga
     7561 tgttcaagga aagacatgta tcatggtaga tgatatcttg aacacaggag caacgcttgc
     7621 acgagcagca aatgtattaa aagaaaacgg cgcaaaagaa gtatatgcct gtgcgtcaca
     7681 tggattattg tccgatcatg cgaaaagtat tttagacaat gcaccaatca aagatatttg
     7741 tatcactgat tctgttttca cagaagaaaa tcgtcatcca gaaaacttaa caatcgttac
     7801 atgttcagaa ttaatgggtg aagcggtcaa acgcatccat gaaaatacac cgatgagtcc
     7861 gttattccgt ctggaagaaa aagaattcga ataaacaaaa aaaagaggga aagaagttgt
     7921 gacagaagtg agcagcttca aggagctgcg acaagacttt tgtcacagct ccttttttct
     7981 atgcccatga aacgtcctct agacaaaaat gagctcttct ttggtttgtt cgctatttta
     8041 tgctagaatg tgcctagcaa taatttggaa gggatgaatg aagtgaaaac tatttatctg
     8101 gatcatgcgg caactacccc catgcatcca caagtaattg aagcgatgac ggcaatcatg
     8161 caagacacgt ttggaaatcc ttcaagcata catggatttg gtcgccacgc gcatgaaaaa
     8221 ttggaaacag caagacaaat cattgcagac agtctgcaag caaaacctca cgagatcatc
     8281 tttaacagtg ggggaacaga aggggataat acagctatct tagaaacagc gttctcgcgt
     8341 caaaaagaag gcagacatct aatcactaca gctatcgaac atcctgctgt tcttaatacc
     8401 atgaaatatt tagagacaaa ggggtttgac gttacatatc tgcctgtaga tgaaaaaggg
     8461 aatctgtcga tcgaagaggt caaaaaagcg ttacgagaag atacgatctt ggtctctgtg
     8521 atgtacggga acaatgaaat cggaaatttg atgccaatca aagaaatcgg tgaactttta
     8581 gcggatcatc cagcttattt ccatacagat gcggtacaag cgtacggaaa ccaaacgatc
     8641 catccagaag aattaggaat cgatttatta agtatctctg ctcataaaat caatgggcca
     8701 aaaggcgtcg gtttcttata taaacgagac ggagtaaata tccctgcatt gcttttaggc
     8761 ggggagcagg aagaaaagcg gcgtgcaggt acagaaaatt tagcagggat ctggggtatg
     8821 gcaaaagcag ttgaactgct gtcacctgaa gaacgtgaag cacgtaacaa caaatataaa
     8881 ggattccagc aattgattct tgatacatta gaagcaaacg aaatccctta tcaagtaaat
     8941 ggtgatttaa cgaataaact ccctcatgtg ttgaatcttc gcttaattgg cgaagcaaat
     9001 gatttgctac tgatgaagct tgatcttaat ggggtcgcta tttctactgg ttcagcttgt
     9061 acagcaggaa atatcgagcc ttcacacgta ttagaagcaa tgtatggaga agatacaccg
     9121 atactaaaag aatccatccg tatcagcttt ggtttgggaa ataccgaaga cgacatccag
     9181 tatttccttg atcaattagt tcgtgctgtc aaaaaataac tagtgaagtc attcttatat
     9241 gaacagatgt ctgagagaac gccttcattt tttagggaac ttaactgaaa aacctagtaa
     9301 aaatcaggat aaacttttat aataaagaga aactaatttt atcgaggtga aaatcatggc
     9361 atttgaaaca acagcaacgg tactgggcgc accaattagc tatcgtttgc atcctgatgc
     9421 aaaaagatat acattgcgcg ataatggatt tacagaaaca aacggaggca attatcaatt
     9481 gatccgacca ttagatgcca cgccgcaaag caaagaagga ttcaaattaa aaatcactgt
     9541 atcaaaagat attcaaacat tgaaaatgtc gatcactaca gcaaatggat tgaaagcagt
     9601 caatattttc aaagatccaa aacagaaaat gagccaagat aaattttatt ttctgatgga
     9661 tgggatgatt agccgtgggt tattcgaaaa agtcgaatga tctgtggata taaaaagaca
     9721 actagttttg aaacggccta ttgttagatg actaactttg taaggacgac gcaaattagt
     9781 tgtctttttt atttttaaat ttaacacatg ttgttatttt taatattttg ctgatttatt
     9841 gtttctaagt aaagaaattt aaattgaaac gattgttatt tagggaaaaa ggtatttttt
     9901 gaaaaaagaa tcccgtataa tgattgttgt gcaaacgcta tacaaaatga aaaagaaaag
     9961 agggatgttt atggaaaatg aacagtcggt cgttttaacg aattggaaga gaaattattt
    10021 gttcttttta tcgggacagt ttttgtcagg aatcactagt atggtcgtcc aatatgcgat
    10081 catctggtat ttgacaagag aaaccggttc ggcgacaatt ttgagttttg ctactttact
    10141 aggaatgatt cccatggttt tactaagccc atttgtagga ccgctagtgg atcgctggga
    10201 taaaaaagct cttttgattg tcacggatat tattgtagcg attttcgcgc ttattttagc
    10261 agtagtcgga acgatttcag aatccttccc gatttggcta gtttttgtgt ctttgtttat
    10321 gcgttcggtc gcacaaacat tccaaatgcc aacgatccag tcgattatgc cgacaatcgt
    10381 tccatcttct cacataacaa ggacgaatgg acagttagga atggtccaat cagcgaattt
    10441 catcattgcg ccagctctag gtgcggcttt gttttcagtc gttcctgtca attaccttat
    10501 tttattagat gtattggggg cagtttttgg tgtcggctta ttgatttttg tgaagatccc
    10561 aaaagtttct cctgaaatat tggaagttcc gcttactatt tttaaagatg caaaatttgg
    10621 gctgcagcaa ttgatggata ataaagggtt atggtacata acgatcaatg gtgcatttgt
    10681 gatgctgttg ttcatgccag caatcagtct gtatccattg atgacgctag attactttgg
    10741 tggttccgtt ggacaggcgg gagcagtgga agtagtctac gcagtcggaa tgctcttagg
    10801 cggtgcactg atcagtttta taggaacatg gaaagaccga atgaaaccta ttattatagc
    10861 ctacatcatt atgggcctga cgatcggtgc aagcggattg gttccaaacg atagtcaagg
    10921 gttcttgtac tttcttatct tgaatgcagg agcaggttgt gcaacgccat atttcaatac
    10981 actgctgatg gcaatgatcc agcagagtta tgaatcgaat gttttaggtc gtgtcttagg
    11041 gaacttcaac tctttgatga acctggcagg tccaattgga ttattatttg caggaccatt
    11101 agctgatcgt ttaggggtag aaaaaatgtt cttgttttcc ggaatcggga ttttattatg
    11161 cggaatcgtt ttatttttaa cgtcagctgc ccgaaattat gataaagaat tacagaaaaa
    11221 actggtaaaa gaacaccatg agcaaaaaga cgaatagtat ggaatggagt tgtgacagaa
    11281 gtcttgttac aactccattt ctgatcctaa tgttcctgtg gcaataagcc tactcaaatg
    11341 aaaaatatga gtaattatct ttatttgttt aatacttgat atagggcagt tttttcacga
    11401 cctatcgtac ttcctctttg cttcatagat ttctttgatt tgttgctcag ataacggagt
    11461 gccaaatggt agtttttcct ttaagagttc tctttccggt gcgtctacgc ctacattgac
    11521 atcgttctcg ataggtacgc tgtaatgatg gatatgtcca tgaagattgc ggatagtgtc
    11581 gttaggcccg agcaacatcg gataatgagt caagtaatat tgttgatggt cgaatttaac
    11641 gatggcacct acatcataaa aataaaattt gggacttccg tcagtaagcc taggatcatt
    11701 tttttctaaa taacggaaaa aagcgcgact gtcatggttc cctttgatca agtggattgt
    11761 tccttgcagt tgagtgacca gttccaaaat ttctgcattt gctttttcat attgcggatg
    11821 catagcaagg tcgcctagat gataaacatg gtcggtttct tttattactg cattccagct
    11881 agtgatcaac tgttggttca tttcatccac atttgcaaag agccgcggag caaagtcgtt
    11941 ttttcctaat aagcgttcat ggaaaaagtg catatcactg ataaagtaat tcatgtatct
    12001 tttgcctccc ttttttctta gagtaaacaa aatcacttat ctgagcaact cataacatct
    12061 aaaaagaaaa ggttgtaaat gagacgtgca gctttaagcg ataagaagca attttgaaaa
    12121 atagtttttc acaatttata aaattattcc ttattgccga aaggctggcc ctttttatga
    12181 gtatgccaat tttttatatc gaatgctcaa aagatgagtg attttttggt tgactatcat
    12241 gtttgtgtac tgaataggtc cagtagaaca gtatttttac gacttgataa ttaagggatg
    12301 aaattttcag aaatatgacg tataatgtaa aatactgaaa agttgcgacc ttcaactcgt
    12361 agatgtttca gaatctaatt gaaatgatgg tgatatcatg acagacaaca gcaaaacacg
    12421 cgttgtcgta gggatgagcg gcggtgtcga ctcatctgta acagcacttt tgttaaagga
    12481 acaaggatac gacgtgatcg gaatattcat gaaaaattgg gatgacacgg acgaaaacgg
    12541 tgtatgcacg gccacggaag attataagga tgtagcgaaa gtagctgctc aaatcgggat
    12601 tccttattac tctgtgaatt ttgaaaaaga atattgggat cgtgtatttg aatatttcct
    12661 agccgaatac cgcgcaggac gtacacctaa cccagacgtg atgtgcaaca aagaaatcaa
    12721 attcaaagca ttcttggatt atgcaatgga tcttggcgcc gattatgtag ctactggaca
    12781 ttatgcgcaa gtcactcgcg atgaaaacgg cgtggtccac atgcttcgtg gagtagacaa
    12841 taataaagat caaacttact tccttagcca attatcacaa gaacagcttt caaaaacgat
    12901 gttccctcta ggcggcatgg aaaaatcaga agtacgggca attgctgaac gcgcaggcct
    12961 tgcgactgct aagaaaaaag attcaacggg aatctgcttt attggtgaaa agaacttcaa
    13021 acaatttttg agcaactatc tgccagcaaa aaaaggaaat atggtcactc ttgatggtga
    13081 agtcaaagga caacatgctg gcttgatata ttatacgatt ggtcaacgtc aaggactagg
    13141 gatcggtggc ggaggagatt cgcaagaacc ctggtttgtt gtaggaaaag atctagcgac
    13201 aaacacatta tatgtggggc aagggttcca tcatcctgca ttgtatgcca caagcttgga
    13261 tgcaagtgaa atccacttta cgacgaatga accaatgcca aaagaattca agtgtacagc
    13321 gaaattccgt tatcgtcagc aagacgttcc tgtgacagtt cgcttattgg atgataatcg
    13381 tgcagaagtc gtattcgacg aacctgtacg tgcaatcact cctggacaag cagttgtatt
    13441 ttatgatgga atggaatgtc tgggtggtgg tttgatcgac cacgcatatc aagaaacaaa
    13501 agttttacaa tacgtttaag cgatattaaa tgaatcaaaa cagctatggc taacaaaaga
    13561 aacacctttt cttttggata gcatagctgt ttttttgcaa taaaattaat ttttattcat
    13621 tttatacttg aaatacttgt gtaaaaagtt cataatatcc aataatatga ataaagttgc
    13681 tttttgttaa gcaagagcag ttgcaaaata gaagggaatc ttttgcaagt gatttgttca
    13741 attttataag tgagggtgat ggaaatggaa aagaaatcga cgggtattag caaatgggga
    13801 ctggttgctc tggttgtcag ttcgtcaatc ggaagcggtg tgtttgggat cacaagtgat
    13861 ctggctagtt ctgcagctcc agggccagcg atcctttcat ggataatcgt tgggattggt
    13921 attttagctt tggtattatc gctgaatcat ttaggagaaa agcgtccaga tctagatggt
    13981 ggtattttcg gttacgcgga agcttcattt ggtaaattag gtggcttcat cagtggttgg
    14041 ggttactggt tgtctgcgtg gctgggaaat gttgcttttg caacgatgct gatgagcgcc
    14101 atgggagaat ttttcccgat attcaaaggt ggacaaaatg ttccttctat tttatttgca
    14161 agtattttta tttggggtct gactttatta gtaaacaatg gagttgaagg agcgagcgtc
    14221 atcaatacaa tcgtgacgat ctgtaaatta gtgccattat tcctattttt aatatttgta
    14281 tttatcgcat ttaaagtgaa tatattcact gctgattttt ggggtaacgt atctgataat
    14341 ctagtgaatg gaacagggca gcaaggaacg atctggttgc agattaaagg ttgtttgatg
    14401 gttatgatgt gggtctttgt agggatcgaa ggcgcaagtg ttttagccaa ccgcgcgaag
    14461 aaacgttcag aagcccagca agcatcgatc attggtctgc tttgtttatt gtttatctat
    14521 atccttgctt cgatcttgcc atacggcgtc ttatctcaag aagagttagc aactatttca
    14581 caacctgcta tggcaaatat tttaaaagga atcgtgggaa attggggagc agcgctgatc
    14641 aatatcggct tgattatttc gatcattggt tcttggttgt cttggacgat gctcccagca
    14701 gaaacaacga tgttgatggc tcgagacggt ctgttgccga aaggttgggg aaaaacgaat
    14761 aaaaaaaatg ccccaactta ttcgttagtt gttactgcaa tcttgactaa tctattctta
    14821 ttgactttct tagttactga ttatgcctat caatttgcct attctttatg tacagcggca
    14881 attttgattt gttatctact tgtcgggatc tatcaagtcc agttttcttt aaaagaagga
    14941 atcaaaaaac aagtagtgat cggtgggatt gctgtagttt ttgaattgat gggcatcatt
    15001 ttagcaggat tttcttatgt ccttttatgt agtattgcct atcttcctgg tttttgcttc
    15061 tactggatcg cttgtcgtga aaccaaacat caaattacgg gaaaagaaaa agtaatgatt
    15121 gggctgattt gtgtggccgc actgctttca atcgggttgc ttgctgtagg ctggatcaag
    15181 atataagggg gaaagaaaca tgaaaatcgc aaatttcggt gtagaagaat ggctaaataa
    15241 atgggaaaag aaagcggtat atgatattgc acaaagctcg atcgaagcat tgacattaga
    15301 cgaactcgtt ggcttagatg ggactagcgt aagtaaattt ttcgaaaaac gcaaaaacga
    15361 accattggac tatggctgga tcgaaggatc agatgttttc aaacaagaag tcgcttctct
    15421 ttatcaaacc gtcgatccgg aaaacatctt acaaacgaat ggagcgactg gtgctaatct
    15481 tttagctcta tacgcgttag tggaagcagg agaccatgtt gtttcgatgc ttcctactta
    15541 tcagcaatta tatgacatcc ccaaatcttt aggtgccgct gttgactttg ttcatttgaa
    15601 ggaagaagaa gattggcagt ttgatttaga acagctagaa gccttagtca aacctgaaac
    15661 aaaaatcatc tgtttgaata gtgcaaacaa tcctacaggc acattgctag atcggaaaac
    15721 tttagaaaaa atcgcagaaa ttgctcgtac agtagatgca tatgtattga tagatgaagt
    15781 atatgcgcct ttaacggata aaggtgaatt cttgtcgatc gtagatgtct atgaaaaagg
    15841 tatagcaacc aattccctat ccaaaaccta ctccattcca ggtattcgta ttggctggac
    15901 agctactgga cctgagttgg cagaagtttt tcgaaagtat cgagactaca cgatgatttg
    15961 cggcggagtc ctgtcagatg atcttgctgt acatgcattg aagaataaag aaaaaatatt
    16021 ggcgcgaaac aaaaagatca ttacagagaa ccttgtgatt ttaaaacaat gggtagccaa
    16081 tgaaccgaaa gttgaacttg tcgctcccaa ttacgtctct acttctttca ttaaattagc
    16141 catcgaagaa gatgaccaga cattttgtat caatttatta gaagaaacag gagtactatt
    16201 agtaccagga agtgcctttg atttaccgaa gcatgcccga ctaggttact gttgtaaaaa
    16261 agaaaccttg gaaaagggat tattcctctt atctgagttc ttgaaaaaac aggcctaaac
    16321 aaaaacactg caaggacagt ctgtgacaac tgttcaagca gtgtttttca tttacgctta
    16381 ttgtctatga gaaggagagt gccctgaagc tatggagact cctgaagctt tttcttctgc
    16441 agtttcttgc tgatggatct cttgtgtatt gtgtcgtaca agcaagaagt tgaccaaaac
    16501 aagaagagaa gtcgaaagaa agacgccacg ataaccaaat gcactggaaa cactggagcc
    16561 gatcataggc cctactacgt taccagttgc ttggaaagat tggttataac tgaagatccg
    16621 tccagcagct tgatgaggcg aatattttgt gatcaatgct tggacagcag ggagcagaca
    16681 agcatcagag ataccaatca aaaaacgtaa ggcagctaat tgccaaacat tcgtgacgaa
    16741 tgccattggg atataaacca gaatcgcaaa acccaaacca atcgcaagta ttctttcact
    16801 cccaatcttg tcacctaagc gaccaaatct tggagcggct atcaaagtgg caatcccagg
    16861 tatcgaagca atgattccgc tgatcaacgt aacattccca tgtccatgca gcaattggcg
    16921 aatgtacaga ctgatgattg gactaatgga attgttggat gcttggatga tcatcgttgt
    16981 gacgaacata ccgatgacga cgtgtggata tttcaagtct ttgaaaatct gtttggcaga
    17041 aaccatgttt tcttttttca ctgggacaaa tttttcatgg acgaaaaaca gactcaacaa
    17101 gaagacgaaa aataagatga tccctgtaat gaaaaaggta gggcgatagc caaacgctga
    17161 agcagagatc ccgccaagaa gcggtccaag taatgttcct gtaacagaac cagttgctaa
    17221 ggttccaaga acttgaccac ttttttcttt tggcgtccca gttgcgacaa gggcagtggc
    17281 attactgata taaccagaaa aaatcccttg aagcagacgc aatgcgacta attgatacac
    17341 actagtcacg caacccatca aagaaatgac gattgccatt cctaatgaag cacgcaacag
    17401 catcaatttt cttccttttt ggtcggctaa ttttccccac caaggagaga taagcgtagt
    17461 caccaagaaa gtagatgaaa aagtcaatcc gctccaaaag ttcaattgtg acgtactata
    17521 attacctaac gtatctatgt aaagtgacat aaaaggcatg actaaactaa atccgatacc
    17581 agccataaat gttccaaacc ataagacaaa caagttttgt tcccaagttt ctcttttcct
    17641 aaataatttt tcctttattc ttgcagccaa ttagactcct tctttctgaa aattttcatc
    17701 tacagctctt tattataaac tacaatatgt agtttatcaa tgaaagtctc ttttttctct
    17761 ttctttttcg tggtaaactg aaagagtgaa ggatttattt tatgagagga aacatggaaa
    17821 tgaaaaaaag aaatctgtct caagagaaaa tcatcgactg ctttcgagaa ctagcagaag
    17881 agatggatgt tcagcaaata acctttcagc atttagccaa acgcttggat atcaaggctc
    17941 cctcgctgta taaccatttc aaaaatattc gtgatgtcaa aacagcgcta acagcgaaac
    18001 ttctgcagga acttaatgac cagctgcgac gggctcttgt gggaaaaagt ggtcaggaag
    18061 cactgcagat ctatgcagaa acttatcgat cctttgcttt ttcaaatcaa gcagtgtatg
    18121 agttactgat cagtgtaccg cataccaatg aagctgtttt attagatgga atccatgaaa
    18181 cgaatcagat cattttgcag atatttgagg cttttcaatt aacgaaagaa gaaaaagttc
    18241 atcgaagcag ggaacttcgt agtatgatcc acggttatct ttccttacgt tttttaggat
    18301 actttacaaa agaaccaaca atcgatccag aagacagcta tttttggatg atcaataact
    18361 ttatcgctac tttgccttaa acaatcagat tcatttgtaa caattttaag atgttcatta
    18421 aatgaccctt ttataagaga aaattcttgc aactttcttg aaaagtgact aagatgagtc
    18481 tagaaaagct gaaagaagga gcacgagtat gtatcaagta attaccatgt tcggggacaa
    18541 tgagccttgg tggttttttg aagactggga agaagatatt gaagaagaag aaacattcga
    18601 gtctttcgaa gaagcacgac aagcgtacga aaaacaatgg aacgaaatcc atcaaaatta
    18661 tgaatatatc aatgcaaaaa gtaactttct cagcgccttt tggaatgacg gagatgagcg
    18721 ctggtgtgaa gagtgtgacg atgatttaca gcaatacaag ggacttgcgt tgttgaaaaa
    18781 tcatcagccc atcacagtag aaagcagaaa ggaattttat gaaacaacta attctagcgg
    18841 aaaaaccaag cgttgcgaaa gacctaagca aggtgcttgg tgctaatcaa aagcacaaaa
    18901 attattatga aggacccaag gtgatcgtta cttgggccct tggtcattta ttaggattga
    18961 aaatgccgga agatctgaat aaggaatggc agagctggca aatggacacg ttgccaatga
    19021 tccctaaaaa actaggaatc aaaccacttc ctaaaacagg acatcaatta aaagcaatca
    19081 agcagctggc tcagcgaaaa gatgtctcag aagcagtcat tgcgacagat gccggaagag
    19141 aaggggaact tgttgctcgc tggatcttag agtatgtgca tttcaataaa ccagtgaagc
    19201 ggttatggat ctcttctcaa acagataaag caatcaaaac tggattcaag caactaagac
    19261 ctgcgaaaga atatgatgca ttgtatgaat ctgctcttgc ccgggcaaaa gcggactggc
    19321 tggtaggatt gaatgtgacc agagccttaa ctgtgaagta cgcggataat ttatcagcag
    19381 gccgtgtgca gacaccgaca ctagcattag tgagagacca agaaaagaaa atcgagcagt
    19441 tccgtccaca aacgtatttc acgatcacgt tgcaagctgg aaaagaacaa gccaaaatgc
    19501 ttcaaaaaaa tcaatttgct ttaaaaacac aagaagaagc acaaaaactt gttcaattga
    19561 tcagtacaag caaaggaact gtcacagaag tccaagaaaa attaaaaacg gaatctgcgc
    19621 cattgcctta tgatttaaca gagatccaaa gagaagccaa tcaacgctat ggctattctg
    19681 caaagaaaac attaagtctt gtacaaagtt tgtatgagac ccataagatc gttacttatc
    19741 cgcgtacaga cagcaaatat ctgacaaatg acatgaaaag tacgatgaaa gaacgattgc
    19801 aagcagtcag cgactttgct cctgaggtca agcagtattt gaaaaacgga gccatcgtcc
    19861 aacagacaaa agtattccaa gacagtaaag tgaccgatca ccatgcactt ttgccaactg
    19921 aaaacagagc acgttatgaa aaattaagta atgaagagcg aaaaatctat caaatgattg
    19981 tctctcgttt tttaggactg tttgctcaac cccataaagt cagccaaaca aaagttacgg
    20041 ttgaatttgg taaagaacga ttcatttttc ggcaaaatcg tgtcgtccaa gcaggatgga
    20101 aaggcgaaac tgaaactgag acggaaacag tcaaatggga aaaaggaatg agaatcaatc
    20161 ccgatttcgc catcaaaaaa gaactatctg caccgcctaa accattgtca gaagcaagct
    20221 tgcttggtca aatggaaaaa tacagtctgg gaaccccagc tacgcgtgca gagattatcg
    20281 agaaactaat caaatctgaa ctgatggaac gtacccctca aggactgcaa gtatctccta
    20341 aaggtaagca attattagta ttggtaaatc cctctttagt aacaccagat ttgacagaaa
    20401 gctgggaaaa agaccttgaa gctattgctg caggaaagaa acaagcagga accttcttga
    20461 atggaatcga aaaagaaaca aaacgcttgg tgaatgagat caaatcaagc aaacaagaat
    20521 atcaagattt ctcgattacc caaaagaaat gcccagaatg tggggccaat ctgcgcgaga
    20581 aaaacacacg tgacggcaaa atctatgtct gcaccaattc agattgcaac taccgcagaa
    20641 gaaaagatcc aaaagtctct aatcatcgat gcccgcaatg tcaccggaaa atggaaatca
    20701 tcgaaggtaa aaacggtgct tatttccgtt gtaaatacga tggaacgaca gaaaaattgc
    20761 ttgataaaaa agagcagaag aagaaaatga ccaaacatga agaacgacgc ttgctgaaaa
    20821 aatatgcaca agcagaagaa ccagaagaaa gcccattagc agcagcacta aaagcagcaa
    20881 tgaagaagta ataagatatg aaagaggttg tgatagaagt ggtcagcttc aagaaataag
    20941 aaggaattta cgaaaattgc ttctcaaatt tttgtgaaat ttcggcttat ttccgaagaa
    21001 gctacttctg gaacaccatt tattcggaaa aaaggactgt gacaagactt ttgtcacagt
    21061 cctttttcat ttaaaaaaat gtttacttca tttgacgtat attattggtg aggcttcaat
    21121 tcatttggct tcactttttc tgtttctctt atgatataaa caggacgctg tttcgtttct
    21181 aagaagattt tcccaatata tttcccgatg attccaagac ataacaattg gattccacca
    21241 atgaacagga agatcgagac catggaaggc catcctgatg taggatcacc aaacaacaat
    21301 gcccgcaaaa taatgaacaa aattgcaata ccagaaccga cacaagacaa agcgccgata
    21361 aatgaagcaa tcgttaacgg tgcatccgag aagttcacga taccatcaat cgagtagttg
    21421 aataatttcc agaaggacca agatgtttcg ccagccacac gttcgcggtt ttcataagaa
    21481 atatattctg ttttaaatcc gacccagcta aataatcctt ttgaaaatcg gttgtattct
    21541 gttaattcta ggacggcatc caccatttga cgagtcatca agcggaaatc acgagcgcca
    21601 tcgaccattt ctgtatcgct gattttattg atcaactggt agaatttttt cgcaaagaaa
    21661 ctgcgtatcg caggctcgcc ttcacgagtc gaacgccggg tgccgacaca atcgatatca
    21721 gaagtagtga tccggttgat catctcagga agcagttcgg gcggatcttg cagatcaaca
    21781 tccatcacgg tcactaaatc tcctgtagaa gcttgcaatc cagcgtacag agccgcttct
    21841 ttcccaaaat ttctggaaaa tgagacaaag cggacataag gataagctga ggctagcttc
    21901 ttgattgctg ctaacgtacc gtcttttgat ccgtcgtcaa taaacaaata ttcgaactca
    21961 tgggcacctt tgaatttttc aacctcatca aaaaaaagag gaacagtttt ttcttcatta
    22021 aaacatggga caacaattga tactttcatc gtttctatcc tttcaatcgt atgtttatat
    22081 atggtttaca ttcaaaattt aataaacctt aaataacacc tttaaaattt gattttacgt
    22141 aaaagaacag gtattctttt tgtaaactaa cgtatttagt ttaccatgtt tcctcggttt
    22201 atcaaacttt taagaacaat ttttattagt tggcaagtag ttttggatag agaaaaagga
    22261 ggaagttcca gtctattgac taggagcaaa caaaatgaaa atacacacac ctatcggctt
    22321 tttatggtta gatgcagatg aatccggatt gactgctgta tcttttcagc caatttcaga
    22381 aagcgaatca gcgaatcagc gaattttaac gcgcacacaa gaacagtttg aagaatattt
    22441 tgcgggaaaa agaaaagaat ttgatgttcc tttatctata aagagaggta cgccttttca
    22501 gcaaaatgtc tggaaagctt tgtcgaccat tccttatgga gaaatccgaa cgtataaaga
    22561 agtagccgtt gctgttgata gtccgaaagc tgtgcgagcg attgggcagg caaatcgaac
    22621 caatccattg ccaatcgtta ttccttgtca tcgagtgatc gggcaaaatg gaaaactgac
    22681 aggatatatg ggaaacgcaa tagatggggt tgaaatcaaa cgccaattgt tgttgttaga
    22741 aggatatctg caaaattaaa aacagttgtg attcggacat tgttccatgc gagaatcaca
    22801 actgtttttt catgttcatt ctaaactttg atcagccaaa taaatagtaa agccatcact
    22861 gtttggagaa gcccgacagc taatccataa gataagaagc gtgtaccttc tttcatgaat
    22921 tttgcaaagt ctaaacgcag accaattgcc gctaaagcag tgatctcaaa ccagctgctg
    22981 ataaaatgtg ccgattggtc aataactaca ggtaaagaaa acaagctgtt gaccaaacaa
    23041 aagatcacaa accctaatac ataccaagga agcggtaatt ttcgtttttt ctgcgtatca
    23101 gttggcgttt caaacagagc tggttgtttc ttgtgcatga atttttcaaa cagatagaca
    23161 acaacaacga gcatcataat acgtagaatc ttaaatagca tggcgaattc gacaacagaa
    23221 ttgtcaagta agcttgcccc agcgactact tgaccaacag attggagtgt accacccaaa
    23281 agtgcacttt tttcaatgag atttccacca aacaactgta atccaagaaa agggagagtc
    23341 aacatcatca cagtacccag tagattgact agtgtgatga tctgtccttt ttcttcctct
    23401 ttcgcatgga tggaaggggc gattgaagca atagcagaag aaccacaaac agcgtttcct
    23461 ccagccatca tcaaagaaga agtatcgctg aattgcagtt ttttaccaat caagtaagca
    23521 ccgatgatag tgactgacat ttgcagtaac acaaaaacaa ttccttttac accaatttga
    23581 gcaatcgttt gagctgtgac agttgcacct agtaaaaaaa cagagaattc taatagtttg
    23641 ctttcagcaa attttgtgcc gattgctaga acaggctgtt taaaaaaagt atttcctaat
    23701 aaaataccca ataaaatagc aatagtcgct ccacctaact gtggcagata aatagcaaga
    23761 agcctgctga aggcagcgat ggcaaaagaa agcagtaaac cgggtaagat ttcgcggacc
    23821 gctgaatcct ttacagattt tattggatgt gacaatgatt tcatttgatc ggttcctttc
    23881 gtcaataaat actaaaagca tactcgaaca tagtagcact aaaccagtat tttgacaaaa
    23941 gaacaagagg tcgtgacaaa agtcttgtac gacctcttgt ttcgaataaa cggtgttcca
    24001 gaagtagctt ctacggaaat aagccgaaat ttcacaaaaa tttgagaagc aattttcgta
    24061 aattccttct tatttcttga agctgaccac ttcttttacg acctcttggt aaacggtgtt
    24121 caaaagcttg catctgcggt aataagccca accagtacaa aaacatgaac agctgttttt
    24181 gtttggccgt tcttattact tgatgcagaa cagctttttc acaacctatt gaatcgatta
    24241 ttaagcgatt tttttagaaa caaattttcc atgtttgcta tgttctttaa ttaagaaacg
    24301 tacgtaatga gcaagaacgt agaagacaac tacacttgca aacagacatt ccgcaacttt
    24361 taagaaatcc aatacgctac tatagatacc taaactgttg aagtaatgaa cagtagtaaa
    24421 tatagctgtt gcagagataa caagcgggaa tgtaaaggct gcatagcttg gataaaaacg
    24481 aagcttgaac aaacgtggaa gcatagacag cacaacgaaa tacaatactt gagataaagc
    24541 gaacaatgct acgacaagat aaaaattagg ttcagcaaag tttttaagat aacctgttag
    24601 gcaaagagaa ccaggtgctg caacgatcgt aatcagcgga cgtgtcggat gagccatatt
    24661 tcttacgaaa aagacacgtt tgatgatgat cggcaataag aacgcatagc agatcaatga
    24721 aatccaaaag aaaatttttc caataagtgg gaagaagttc ccggcagtta cagtgatgac
    24781 cccaaatcca acgtaaatga taaaccagct tggataaatt gcttcaattg aaagatcagc
    24841 tttgataaca tggtgataat tgaaataaaa gacaaggatc acttggaaga taacagcgca
    24901 cagccaaatg aatttgacaa ttggtgcaat actttcatat gaaacaaaat aagtacaaat
    24961 aaccatgagt gacatcgtaa aagttggtga aacggaggcg atgattggat catgcaacgt
    25021 ttgtttcgtg tgttcgaata agataaacaa tttaacaaaa atgaatatca taagaatcat
    25081 agagataccg ccagttagat tgcctaaagc aacatggtga tagtctttaa acagatttcc
    25141 aagggaagct aacccaagga tcaacccgca gatcgggatc ggaataattt tcaaaaagtt
    25201 cttcatatat aatattctcc tttttattta atagatttta gtaccaagat gaacgaatac
    25261 attgtaaaat gaataggaat gtatgattac gagcaagcag acagctgatt gtcttcatct
    25321 aagttactag ttggatcagc aactgttttg ttgtacattt ctattataga tggttttttg
    25381 tatatttaaa tcaaatagtt tttatagtaa ttatcataaa aagttatgga agtggtgcca
    25441 tgtttaagtt attaacgact tttcgagcag tatatgaaac aagaaatttt tccagagcag
    25501 cagaagtact gtttttatct caaccagcag tctcgaatca aatcaaacag ttggagcggg
    25561 aattgaatat cgatcttttt caacgtaacg gaagaaaaga gatgcttcca actaagcaag
    25621 ccgacttatt atatgaacgg acactggttt tgttagaaga atgggaagaa actcagcaaa
    25681 aattgctcaa tgaacaaaat gaagaagaag tatgtcggat cgttgcttcc cacacctttg
    25741 ctgtctatct tttgcctcag ttgatgaaac atctgatcaa aaggtttcct aaagtgcatt
    25801 ttgagatcga aatcacgaat tctcatgaat cattagaaca agtagcgaaa catgaatccg
    25861 attttggttt tatcgaaaag ccattagaga cttccggcgt acaaagatac tctttgatgg
    25921 aagaccagct agtcatcgct ggggacccaa aaagcaaatt gtggcttgta agagaagcaa
    25981 actctggtgt ttttcattac acgcagcgtt attttgaaga gatgaatatc caagataaga
    26041 agatgatcgt gaaaagtaac gatgtaattg ttgcgttgct gaaggaagga atcggtcgct
    26101 cgattttgtc taagcgctct gttccagaaa atgtgccaat gactccgttg aatttccatc
    26161 gatattttta tttcatccaa cgaaccaatc tggtttctga tcagctgcta gagattgccg
    26221 aagagatcct tcgatacaat gaaagcacag aaacttctca cagcgaggag aatctcagct
    26281 ggtagataat tgcatgtatc aaaaaaagtt ctatgataca ctaaagataa gcagtaggct
    26341 tttgtactgc atttgctcaa gcaactgcac aaacggaaag ttaatttttc ccaaatgtct
    26401 atggaaagac tttccattat ctaactggac cgctataata atcagcagta tggtttttaa
    26461 gaaaagggat gaaacatgga aaaaaaatta aaagcttcga acgataatcg tattgattat
    26521 ggcgtgattt taccagtctt tctgttatgt ttgattggtc tgctctcatt atatgtagca
    26581 cttagccatg atccgaacaa tccagcagtc ttgaaaggcg tagggatgca agttgtctgg
    26641 tatttagttg gagcggcagc aatcgttgtc atcatgcatt tgaattccaa atggatctgg
    26701 aaactgactc cttaccttta tggtttgggg ttagtggtaa tgggactctt gctcaaattc
    26761 tatgatcaga atttagctgc ttcaacaggg tctaaaaact ggtttcgatt cggtgcgttt
    26821 actttccagc cagcagagtt gatgaagatt gcgtacatct tgatgatggc actgatcgta
    26881 actaaacata atacgcaagt aaaagaacgg acgatgaaat cggacttttg gctgattggg
    26941 aagctcttga tcgtgacaat accggtttta gcattgatca tggcccaaga tgactttgga
    27001 acgatgcttg tctttcttgc gatctttggc gggattttcc tgatgtctgg aatctcttgg
    27061 cgcatcatcg cacctgtagt aatcttggca gtagtcgttg gagcaggaac gatcttcttg
    27121 gttacgactg aaggcggaag agacttgctt tataaagttg gattcaaatc ttatcagttt
    27181 gcacgtattg attcatggct ggaccctttc catgatacgt caggaatgag ttatcagccg
    27241 gcccaaggac ttttggcaat tggtaccggt ggcttgtttg gtaaaggatt caacgtaagc
    27301 aatatctatg tgcctgttcg tgagtccgat atgattttta ccgttatcgg tgaaaacttc
    27361 ggctttatcg gtggtgcatt cgtcattttc ttgtatttta ttttaatcta tcgtatgatt
    27421 cgggtgtgtt tcgatacgaa taatgaattt tacgcctata tcgcaagcgg tttgatcatg
    27481 atgctgctgt tccatgtctt tgagaatatt ggagcaaata tcggattact tcctttaaca
    27541 gggatcccat tgcctttcat tagtcaggga ggatcctcga ttttagggaa catgatcggt
    27601 atcgggttga tattatcgat gagataccaa aatgaagcac ctgcaagatc ttcaaggagg
    27661 taagaaaatt gtacaccttt tactggtacc cgaaatgttc aacatgcaaa aaagccaaag
    27721 cgtggttaga ccagcatggc gttagttatc aaaccgttga tatgatcaaa gaagtaccga
    27781 aggcctcaac gattgagact tggctagaaa cgagtcaagt accaatccgt cgcctgttca
    27841 acacaagcgg gatgaaatat cgggaacttg gactgaaaga tcaagtaggc gagtttacgg
    27901 cttcaaaagc gagccaagtc ttatcgacag atggtatgct gatcaagcga ccactgatct
    27961 tacgagagga ccagcttgtt gcaattggat tcaatgaaaa aatttatgaa ggagaactga
    28021 tataaaatgg caggcaagca tttgaagaaa aaggacaacc tttggatctt atttaatgga
    28081 aaagaatact gtgttggttt gacaaatgaa gcgcaagaag aacttggaga catcacgttt
    28141 gccaatctgc caaaagcagg acaatcgcta aaaaaagatg aacctctgat cgaagttgaa
    28201 gcggaaaaag cggtcaatga atttgccagc ccgctaacgg gtacagtttc ttctgttaat
    28261 gataaaatcg gtgaagatat caatatcttg aatgattcag atgaaatgaa tgcgtggatc
    28321 ttaagtttca aagatgttga tccaaaagaa tttgacgaat tataaaatca gaaaatcact
    28381 tgaaaaaagt tgacactgat tcttccagtt gctataatca taagcaatcc tatatgaaac
    28441 gagaaagctt tgaaaagaag agtacatgtc acggacgttt gaagagagcc ctgtttgctg
    28501 aaaatgggta acgaaaatga gatggaagat ggtcttagag cagagtaagc gagcgtaagc
    28561 aaacttacta cgggagtgcc cgttacagcg cgacagtata cggaaagaag ctaagtccaa
    28621 gtactggaag aggctgttat tgcgaagtaa cggtaaatca aggtggtaac acggaagttc
    28681 aagctttcgt ccttttgctt aaggcaagag ggcgaaggct tttttgtttg aaaaatcata
    28741 agagaaagat gtgaatggca tgtcattaat ccaactaacg aatgtcaaaa agacattcaa
    28801 tgggaaaaac ggaaacatcc aagccgtcaa tgacgtttca ctaaacgttg aaaaagggga
    28861 tatttatgga atcgtcggct attctggcgc aggaaaaagt acattagtcc gtctcctgaa
    28921 tggacttgag cttcccacga gcggcgaagt gatcgtaaac gatcaagata ttacaaaatt
    28981 aaaaaacaaa gaattacgta cattccgaaa gaaaatcggt atgatcttcc agcatttcaa
    29041 cctgttatgg tcaagaactg tacttgaaaa tatccagctg ccgctggaat tagctggcgt
    29101 accaaagagc aaacgtaaag aacgggcaga agaactgttg cgtttagtcg ggttagaagg
    29161 acgcggacaa gcatatcctt cacaactttc cggcggacag aaacaacgcg tcggtatcgc
    29221 acgagcattg gcaaatgatc ctgagatcct gctttgtgat gaggctacta gcgcattgga
    29281 cccgcaaaca acagaagaag tattagactt attgttagcg atcaataaga aattgaattt
    29341 gaccatcgtc ttgatcacac atgaaatgaa tgtgatccgc aaaatctgca acaaagtcgc
    29401 tgtgatggag ttggggaaag tcgtagaaga aggagacgta ttgactgtct tcagacaacc
    29461 gaaaaaagaa gtaaccaaac gctttgtaca acaagacatc gaaccagaag ctgattcgac
    29521 agaactatta gctgaactca tcaaagaaaa tccaagcggc cgtttggcaa ctttgacctt
    29581 tagcgaaaga aatgccaacg agccagtcat ttcccaagcg attcgacgct ataacatcga
    29641 tgtcaacgtt gtgtatggaa agatcaaaca agtgaaagaa ggttcctttg gttcattgac
    29701 tgtcttgatg actggtgaaa ccaaagaatt agatcaagca gaagtgttca tcaaagaaca
    29761 aggagtagga attgaggtga tccatcgtgg ataaaagctt ttcagaaaca tatctagatt
    29821 ttaaacaaat caacccggaa acgatgaatc aggctatcct tgatacacta tatatgacat
    29881 taatctcaat ggtcttagtg acgatcatcg gattagtttt gggattgatc ctttactcta
    29941 ttggacgcaa aaacaaaccg tatgctcgaa tcatttatgg aatcgtatcg atcatcagta
    30001 atattttccg gtcaacgcca tttatgatcc tgatggtttt gatcattcca tttactaaag
    30061 caatcgtagg cactatgcta ggtgcgcaag cagccattcc agctcttgtt ttatccgcag
    30121 caccatttta tgcccgtcta gtagagattg cttttcgtga agtcagccct ggtgtactgg
    30181 aagcagcaga tgcaatggga gcaagttact gggaaatcat ctggaaggtc ttgatacctg
    30241 aaagtattcc cgcattgatt tctggattaa cagttacaac gatctcgatg atcggattta
    30301 ctgcgatggc cggcgcgatc ggcgcaggtg gacttggagg tcttgcttgg caggaaggct
    30361 accagcgtgg taatctaaca gtgacattcg ttgcgacttt aattatttta ctaatcgtat
    30421 ttatcgttca aggaatcggt gatttcttaa ctaagaaaac agacaaaaga taataggata
    30481 tagggggatg taggatatga aaaagaaaat ttttggattt gcagcagcgc ttttgctgac
    30541 tgtaggatta gcagcatgcg gtaacaacag cgacagcaaa gattcagcaa ataaagcaga
    30601 cgacacgaca ttgaaagtcg gcgcttcacc gacaccgcac gcagagattt tggaacatgt
    30661 gaaaccatta ttgaaagatg aaggaatcga tcttgaaatc gtcaaattcg atgactatgt
    30721 attaccgaac caatctttgg aagaaggcga cattgatgcc aattacttcc agcatattcc
    30781 ttatttgaac aaagaaatca aagaaaaagg atatgacttt gtcaatgccg gtgctgtcca
    30841 catcgaacca atgggcttgt actctaaaaa agtcaaagat gtttccgaat taaaagatgg
    30901 tgcaacaatc attacttcaa attctgaatc agactgggga cgcatcatca caattctaca
    30961 agatgctggc ttagtcaaag tcaaagatgg agtagatctg gaaacagcaa cattcgatga
    31021 tattgaagaa aaccctaaga acttgaagtt caaccatacg atcgacccat cacttttagc
    31081 ttctacgtac caaaatgatg aaggtgacct agttgcaatc aacgcaaact tcgcttacgg
    31141 cgcagggttg aatccattag aagatgccgt attgcttgaa aaggacaact ctccttacgt
    31201 gaatattatt gcgactcgta aaggtgatga agacagtgac aaaatcaaaa aactgattga
    31261 agtgcttcac cgcaaagaag tccaagaatg gatcacagac aaatggggcg gctctgttaa
    31321 accagtaaag gctgatgcaa aataaggtat ggaacaaaaa agatgagaaa taagtctgta
    31381 atggcttatt tctcatcttt tttataccta ttctaattta gaaatcaaaa ttgtttaata
    31441 ataaataaaa gatatttgat tttagtaagg aaggtcattg cgcttcattc tcaattagtc
    31501 taaaatgagt gagaacgaaa gagaatttgg gggtataatg catgtctgtc ttagaaataa
    31561 aaaatctaca tgtgtcgatc gaggaaaaag aaatccttaa aggcgtaaac ctaacaatga
    31621 aaaccggaga aatccatgcc atcatgggac ctaacggcac aggaaaatct accttatctg
    31681 ccgctatcat gggcaatcca aactatgaag taacagaagg cgaaattttg tttgacggga
    31741 aaaatgtttt agacttggaa gtagatgaac gtgcgcgact tggcttattt ttagctatgc
    31801 aatatccaag tgagatacca ggtatcacga atgcggaatt catgcgtgca gcgatcaatg
    31861 cgaaacgtga tgaaaacgac aaaatttctg ttatggcatt tttgaaaaag ttagatgaaa
    31921 aaatggcttt actaaatatg ccagaagaaa tggctgaacg ttatctgaac gaaggttttt
    31981 ctggcggaga aaagaaacgg aatgagatcc tgcaattgtt gatgttagaa cctacatttg
    32041 caattttaga cgaaatcgat tcaggtctgg atatcgatgc tttgaaagtc gttgctaaag
    32101 gagtaaatga aatgcgcgga gacaatttcg gtgcattgat catcacccac tatcaacgat
    32161 tattgaacta tatcacacct gatgtcgttc acatcatgat ggaaggccga gtagtcatga
    32221 cagggaatgc tgacctagct aaacgtctgg aagcagaagg ctacgctggt atcagtaaag
    32281 aattaggaat cgactataaa gaagaagaag cgtaaggggg agcaagaatg aaagaaaaaa
    32341 actggctcga ttatcttgac gcggtaaatg atttttcttt aagtaaaggc gaacctgatt
    32401 ggatgagaac cttccgtcaa gacgcactag cgaaagcaga tgaactgcca ttgccgcata
    32461 tcgatcgggt gaaattccat cgctggtcgt tatttgatgt gaaagaaaca caaaccatca
    32521 gtgaaacagg cacgattccg gcatttgatg caatgaaaga caatcctgtg cttgtccaac
    32581 aaggttcatg gacgattttt gaacaactgc ctgtggaatt agcagaaaaa ggagtcattt
    32641 ttaccgactt gttcactgca atgatcgaat atccagaact agtccaagaa tattatatga
    32701 aaaaagcagt aaacatgaac gaagaccaat tgactgcact ccatgtagct tttatgaaca
    32761 gcggtatttt cctgtatgtg cctaaaaatg tcgtgatcga tgaaccactc gagtccttat
    32821 tcattcaaga tggcgcatcc gatgagcact tcttcaagca tgtgttgatc gtggcagatg
    32881 aacatagtga attttcttat ctggaacgtt tccagacaac caaagaacaa gtagcaaaat
    32941 catcaggtaa tatcatcgtg gaagtcatcg ctaaagctgg ttcaaaaatc aaatattcag
    33001 ccgtagatca attaggagaa aatattactt cttatatgaa tcgccgtggg cacattttac
    33061 gagatgcttc tgtcgactgg gcaattggtg tcatgaatga cggtcatgtg atcgctgact
    33121 ttgactcaga tttagcagga gaaggtgcac acgcagaagt caaaatcgtg gcaatcagct
    33181 cgggcagaca aatccaagga atcgatacac gagtaaccaa taaagcccct catacgatcg
    33241 ggcatatttt gcaacacgga gtgatccgag aaaaaggaac attgaccttt aatggtatcg
    33301 gccacatctt gaaaggggca aaaggtgcag atgcccaaca agaaagtcgt gtcttgatgc
    33361 tttctgataa agcacgtggt gatgcgaatc ctattctttt gatcgatgaa aacgaagtaa
    33421 ctgctggaca tgctgccagt gtaggacgag ttgatccaga agaaatgtac tatctgatga
    33481 gtagaggatt gcataaagaa gaagcagagc gcttagtgat tcgaggattc ctcggttctg
    33541 tcttaacagc aatccctgta gaacaagttc ggaaagaatt agtcgaagta atcgaaggga
    33601 agttgaatgg atgatcgatg ctaaaaagct acgcaatgat tttcctatct tatttcaaga
    33661 cgtcaatgat gaacctttag tttatctgga taatgcagcg acgacccaaa agccaaaaca
    33721 agtactccag gcattagcgt actattacga acacgataac gccaatgttc atcgcggtgt
    33781 ccatacgtta gcagaacgcg cgacccatga ttatgaacaa gcaagagaaa aagtacgggc
    33841 gttcatccat gcaaaagaaa cagcagaagt gctgtttact cgtggtacga cgacaagctt
    33901 gaattgggta gccagaacct tcggcgaccg ctatatcaaa gcaggagacg agatagtgct
    33961 ctcttacatg gaacatcatt ctaatgttat cccgtggcag cagttggcaa aacgaacagg
    34021 tgctgtcttg aaatatatcg aactaacaga agaaggcttc ctggatatgg aggatgcagc
    34081 gaaaaagatt acggacaaaa ccaaaatcgt ctccattgct catgtatcca atgtcttagg
    34141 tgtcttcaat cctgttcaag aattagctga acttgtccat gaaaacggcg gggtcatcgt
    34201 agtagatggt gctcaatctg ccccgcacat ggccattgat gtccaagcac tagactgtga
    34261 tttctttgct ttcagcggac acaaaatgtg cggaccaaca ggtattggtg ttttatatgg
    34321 taaacgaaaa tggttagaag aaatggaacc tgttgaattt ggtggcgaaa tgatcgattt
    34381 tgtcgaatta tacgacagta catggaaaga actaccttgg aaattcgaag cagggacacc
    34441 aaatatcgcc ggcgctatcg cattaggcca tgcaatcgat tatttgcaaa aactcggtat
    34501 ggacaatatc catcgatatg aagaagaact agccgcttat gtgttgccaa aattacaagc
    34561 aattgatgga ttgactgttt atggtccaca agacccgaat tttcggacag gagtcgttgc
    34621 attcaatttg gatgggttac atccccatga tgtcgcgaca gctttagaca tggaaggggt
    34681 agccgtcaga gcaggtcatc attgtgcgca accgctattg aagtaccttg aagtatcagc
    34741 gactgctcgc gcgagctttt atttctacaa cacaacgcaa gacgccgacc gtttagttga
    34801 agcaatcatg gcaacaaagg agtttttcca acatgggact atctaaatta gacaatttat
    34861 accgtcaagt gatcttggat cattcttccc atccgcatca tcgtggaagc ttgactgact
    34921 cgacaagcaa gatcgaattg aacaacccca catgtggaga tgtgatcgaa ttgcaagtcg
    34981 atgtaaaaga cggaatcatc aaaaatatcg cctttgacgg cagtggctgc tccatcagta
    35041 cggcaagtgc ctcgatgatg acagacgccg tcatcggaaa atcaatagaa gaagcagaac
    35101 atttaactgt agactttcta cagcttgtcc aaggaaaaga agtcaaagat cccgaccaat
    35161 taggcgatgc tgctatgctt ggtggtgtag ctaaatttcc cgctcggatc aaatgtgcga
    35221 cacttgcctg gaaagcacta ggaaaagcaa tggaaaacga tggtaccgca gctttccatc
    35281 attaccacaa ggaagaggag tgagaacatg ggcgtaccag aattagaaga atataaattc
    35341 gggtttcacg atgatgtcga accggttttc agtacaggag aaggcttgac agaagaagtg
    35401 atccgtgaga tgtcaagaat caaaggcgaa ccagaatgga tgcttgaatt ccgtctgaaa
    35461 tctctagaaa catttaacaa aatgccaatg caaacatggg gccccgacct ttcagacatc
    35521 gatttcgatg ccatcaaata ttaccaaaaa ccaagtgaca aacccgctcg tgactgggaa
    35581 gacgtaccag aaaaaatcaa agatacattt gaaaagattg gtataccaga agctgaacga
    35641 gcttatctag ccggtgcttc cgcacaatat gaatcagaag tcgtgtacca taatatgaaa
    35701 gatgaattcg aaaagttagg aatcgtcttt actgacactg actctgcttt gaaagaatac
    35761 cctgaattat tcaaagagta cttttcaaaa cttgtaccgc caaccgacaa caaattagca
    35821 gcgctgaatt cagccgtatg gtcaggtggg acctttattt acgtgccaaa agccgtcaaa
    35881 gtcgatgttc cattacaaac gtacttccgg atcaatgcgg aaaacacggg gcaattcgaa
    35941 cgtacgctga tcattgttga cgaaggagca agcatccact atgtcgaagg ttgtacggca
    36001 cctacttatt caagtaacag cctgcatgcc gccatcgtag aaatctttac aagaaaagat
    36061 gcgtattgcc gttacacaac gatccaaaac tggtcagaca atgtgtacaa cttagtaacc
    36121 aaacgagcaa aagcatacga aggcgcaacc gttgaatgga tcgacggaaa cctaggtgca
    36181 aaaacaacga tgaaataccc aagtgtttac ttagatggaa aaggtgcacg aggcaccatg
    36241 ctctccatcg cctttgcagg agcaaaccaa atccaagata cgggtgcaaa aatgatccac
    36301 aatgcaccaa atacatctag ctctatcgtc tctaaatcaa tttcaaaaga cggcggagaa
    36361 gtaaactatc gaggacaagt aacctttgcc aaaaacagtg cgggttcgat ctctcatatc
    36421 gaatgtgaca cgatcatcat ggacgaatgg tcgaaatccg atacgatccc attcaatgag
    36481 atccacaaca gccaagtctc tttagaacac gaagccaaag tctcaaaaat ctcagaagaa
    36541 caactctact atctgatgag ccgaggcctg accgaatctg aagcaactga aatgatcgtc
    36601 atgggctttg ttgaaccatt caccaaagaa cttccaatgg aatatgcagt cgaactcaat
    36661 cgattgatca gttatgagat ggaaggcagt gtaggataaa cttgttatag gagctagaat
    36721 ccttggtata taagggttct agctttttta ttttgtctat atactagaaa tgaccagctt
    36781 ttgaccagct cttttactga tgagccatca tatcagcaaa gtcttgacct gttttcttag
    36841 gtgcattatt tgtaatatgt gcatagatgt ctaatgtcac tttactattt tcatgcccta
    36901 atcgttgttg aactaccttg acagattctc ctgcttctaa taataaacta gcatgtgtat
    36961 gtctaaaccc atgaggtgta atacgaggca agttatattt tttcaaaata tatcttaacc
    37021 aatcattaac agtgtttgga atgtatagag tgtttttaac tgttgtaaaa acatgttgct
    37081 ctttagagct agtattgtat ccaagtttta aatactcttc tttttgctgt aatttccagt
    37141 tgttgaggat agaaagagtc tcagtatcta aagagataac tcgtctagaa gctcttgttt
    37201 tcggagattg aattataact ttaccaaatt catctacagc aagagtttta ttgacatgta
    37261 gttctttatt aaacgtgtct atgtctttcc actgtaaagc gagtacttca ctctttctca
    37321 tacctgtgta tgccaataat ctgaagaagg cgtattgttt catgttacca aaatctttaa
    37381 aagcatccag taaattatta agctcctctt ttgagtaaaa tttacgattt ttctcatact
    37441 ctttttttcg tggaagaagt gttttttcca taggattatt gtcaatatat tgcattgcaa
    37501 ccccgtagcg taaaatttgt gcagtctgtt ttctcatata atcgtaactt tcatatttac
    37561 tgtgccattc atctaccact ttttgacaat atgggacaga gatattcgat agtttaagct
    37621 taccaaatgc tggaagtatt tgattatttg cgtatcttac tgagattgcg attgttgaag
    37681 ctttaacact ggtacgctga tgagttatcc attcattata caggtcttca aatgtcatat
    37741 caggtgcttt ctttttaaca ccgtataata tttgatgtct gtactcgtca taatcttttt
    37801 gagcttcttg tttgctacta aaacctcttc tcgtagtatt tattttttca ccagttcgtg
    37861 gatcggtggc aatgtgtcct ttatacatcc acgccacttg accgtttttc tttttgtact
    37921 ttgatatttt tgccatgaaa tcatctcctc ttagtttaca aggagtactt accactagat
    37981 ggtatcacct cccttcattt ttttcttagt gtattttttc ccaattgatg aaatcgtttg
    38041 ttttagcttg tttatattat caataatttc gtttacagct tcttcgggat aattcatgtc
    38101 ttccacttga ctatgtatcc cttcatctat catttcttct agttgttcct ctatactgct
    38161 agtgagcaga agaatgttat tgtcaaattc ttctataata gcattgatga ataattcttc
    38221 tatttttaag atattgaaaa gactaatttt ttcattttta actttattac aagtcttgtt
    38281 agcaataaat tcttgcatct ctggttctaa tttggaatat ctatccagcc atgtatctaa
    38341 attagagtgt actggtggga actgttgacg aagatgctgg aacaggtttt tatctggaaa
    38401 tgttatacca tctagtacaa tgctatctct ataaagaata attcccaaaa tatattcttc
    38461 tacattgcca caaactaact cctctatact catatttccc aaatcagcaa ttcgggataa
    38521 tcgctctggt attggtaaat aggttccctt ttcccattcg tagatagttt ttttgtcaat
    38581 caattgacca ttgttaatca taagaccaaa tgctggttgt gttaattttt tactctttct
    38641 tatagctttt atttttgttc cgagtatctt ttttcgttct aaataattta ttggtggacg
    38701 ctttatcata ttgaccacac ctcctaaaat tagtatacct caaaaagggg gtgttgtaaa
    38761 taaattcaca caacatattg acaccccttt tgtatcgagg tattatgtgt atgtcgatga
    38821 actgataatc attttttatt tgattaatcg gttaataaca acaaaatact tttattttga
    38881 tcaaataata cgaagatgat tcttagaaaa tttgttcaag taatcacgaa aggaggggga
    38941 aatatgtctc tacaaatcat tgatagcatt gtttctatac aagttgaaca acaagtgaaa
    39001 gagataatta cagtgctaaa gcctatgcta gaagacatta tttctggtgt tactctagag
    39061 tatatggact atcagcaggc aagtgaatat ctaggtgtat cagtaggaac gattagaaaa
    39121 tatgtttctc aatacgggtt acctgttata aaaattgata cggtcattag attcaaaaaa
    39181 tctgatattg atagtttcat ggaacagtat aaaggttgag taaacaaata agactaaaac
    39241 atatagtaat aaagagtttg tgtttattat ctgtatgttt tagtctttaa cagaatttta
    39301 taaggaggaa acacaaatgg aaacaccaat gattaatatt ccaattaatg tagataaaga
    39361 aagactatta gagaaaccag ttatagagga tgaaaaaaag agaatacgaa aaagatgttt
    39421 agataactac agagaagtta caagagatga gtttgtagag atactaaatt catcacaatc
    39481 atttattcca agtaagacaa agaataaagg caacaaaagt gaagagtttt tagaaactag
    39541 agtaattatt ctggatgtcg ataacactgt taaagatgag aaggggaagg tagtagattt
    39601 aagtaaagat gatagtagat acttaagcat agaaaaggct ttatctatca atttagttca
    39661 taattctgcg tttgcgatac aaaaaagtat tcggtactct gaaaatctag aaaaattcaa
    39721 gattgtcttt ctattaaaag aagcaattac tgactatagt aaaatgattg ctgtttacga
    39781 atacttgaaa aaaatcatac ccgggtgtga tgacaatgta aatgcttcga atagaatgtt
    39841 ttttggagga tataagtcag atgcagtgat aataattaat gaagacaaca tgttagatat
    39901 tactgagctt ccgattgatt ttaccatgac atgttctaaa aattgtcaaa gtgattcagg
    39961 gagagagtat gaactagtca atgaaactga ttttgttaag ttgataaaaa atgacgacaa
    40021 agaagaaatg aaacagtggt ttaaagactg cctgtttgat tcctccgaca tgtcttttaa
    40081 tgagatttat gaaagattgt taaccattga tatgaataaa ttacttaagt caagtaaaaa
    40141 cttaagatgt ctgtttcacg acgaccataa tccatctgct agtattttta ccagtaaaac
    40201 tgggcattcc attttttatt gtcattccag taattgtggt atcagtgaaa attttattgg
    40261 ggttgtgatg ttaattctag agaaagatag tcgggtagaa acatttaatt ggctattaga
    40321 gaatctagac ctgtatccta cacattttcg aaaattgaaa gaggaatcaa aagtactttt
    40381 tgacactctt gaatctatgg aagacaagct tttcaggaca ataaataatt atctagagga
    40441 aatgcgacgt gtctatgatg ccttgctttc tgatgttaat ttttttgatg atagtaagga
    40501 aagtgtgact tgtattttat caggagaaca actagctaaa aaaatgagtt cttactatgg
    40561 taaaacttat gacatagata aatggaataa gttactatca tttatgacat ttataggatt
    40621 gataaaaaaa ttagatgatg aagatgttcc tttgaagatg ctcgaatacc taaataggtt
    40681 aaaggaagag aaagcgttag gaaactttaa tcataagaga agcaatgtct atcgattaga
    40741 cgtttttaat gcaacttctg tgattcaaaa attgaatgaa gatatccttc cacttctgaa
    40801 aaaagttcat tttacatatc aatatttttc ttatgaatgg gttaagatat gttttaacga
    40861 aaaagaggct aaaagagtat ttcctcaaaa ttttcggtca gaactcagca aggaaaaaca
    40921 attgatttta gatgaggcac atgaagtttt acaggactta tcgtggcaag ggacatatct
    40981 aatgacagag aaagaactta ttaacactgt ttgtgaacgt ctacgtaatg ttgggaataa
    41041 cagcgtggaa aatgctttaa aagaaaacag aggctacttt gttaaacaag gattcactct
    41101 tgaacgagct tctaaggata ttaagaaact atacaatgtg aaagcaagca gtagtttttt
    41161 agtctaccta gcaaaaggag cagggataga tgaagtaata aaagaattga tagcatctgg
    41221 tgttgaatta gttcctcttt atcaatttac aagtgtaaca agagatgatg gacggagagt
    41281 aaggaagaga aaagacccaa ttgtattaaa ctagacaggt tatccatagc tcttaatctt
    41341 atttcatctc aatacaccca ccgttaaagt tcggtgggtt atttattttt caatctttca
    41401 atagctgatt gcgttcattt tcttgccttt ttaatagctt catatagtca attgttcgaa
    41461 ctgcatcttc agtgctaaga gaacgataga gagccaaaaa ctcttcctca taatctacga
    41521 caacattgtc tagaaaatgg cttacagggg ttcctagggc tctagaaaga gctgttaagc
    41581 tatcgaggtt aggctctgtt acagaatttt cccatcttgc tactgcctgt tgtgtagaga
    41641 agattttttc agctaattct ttttgtgtcc acccgagagc ttttcgcttt tctctaatga
    41701 cctttgcata ttgtttctgt ttcattaata cacccccatc tcagtatagt acaacaagtt
    41761 gttgtatttg taatggtatt tgaagttttt atattttatg agttgaaata catcatattg
    41821 ttgtatataa taaaacagga ggggagaatc atgaaaaaag taagtaatct cagccgatac
    41881 agaaaagaaa aaggactttc tcaaacggag ttagcaaaaa aaatgaatgt tacacagcaa
    41941 tgtgtaagtt cgtggcaaac agggagaacg attcctaaac cctatcaaat gaaaatgctt
    42001 tctgagatat taagtgtacc aataaacgag ctgttttctg atgtgtttaa taaagtaaac
    42061 agttaactat taagcaattg aatgatttta ggaggagaag acatgtattg tagaaaatgt
    42121 ggtaaagaaa taacagatga aagtaagtat tgccagtttt gcggagcatt acaagaaaca
    42181 gatgagacaa ctggagcaga cgaagtaaag aaaagtactg agcagacatt tagtgaaatg
    42241 aaggaacaaa tcgtacatgg acaagagaca gggaagctgt atttgattat tggttggatt
    42301 tctatggtag tatcgttagc atttattcct gttgtatttg gtgctgttgc tgttattatg
    42361 ggctacttat atcgagaaaa agatgagaaa atgggtacga ttttgatgat agcaggggta
    42421 gctggagcaa tctttggtgt acttttaggg atgtcaatgt actgataaga gggataagag
    42481 caaattattt tggagatagg agataaaaag ttgaataaag taaatatgaa caagaagttt
    42541 gtcattatag gtatcgttgt cttggctatt ataggtatca ttttttcaaa aatgacaggt
    42601 acatctggat tagagaagtc atctaaacca ttggtgacac agattttaca agaacagtac
    42661 aacttaaata ggtcatgtga tgatgtgacg attactcatg aaaatggaga taacacatac
    42721 cgggctaaag ctacgttaga caatggaagt gctatcaata taaatgtcga gtactatcca
    42781 aagaaagacc gtgtatatgt agagatacca tatactgagg tgttaatgtt aaattgattt
    42841 aaatgtatta tgtataccgt ccaaacagga actcctaaag gtgtaagctt acta
//
LOCUS       DAXLPC010000014        41047 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.014, whole genome shotgun sequence.
ACCESSION   DAXLPC010000014 DAXLPC010000000
VERSION     DAXLPC010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41047
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.014"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(37..1188)
                     /locus_tag="ACF3UE_000719"
     CDS             complement(37..1188)
                     /locus_tag="ACF3UE_000719"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFD3634175.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1201..1638)
                     /locus_tag="ACF3UE_000720"
     CDS             complement(1201..1638)
                     /locus_tag="ACF3UE_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3634176.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1653..3419)
                     /locus_tag="ACF3UE_000721"
     CDS             complement(1653..3419)
                     /locus_tag="ACF3UE_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFD3634177.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3683..4360
                     /locus_tag="ACF3UE_000722"
     CDS             3683..4360
                     /locus_tag="ACF3UE_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD3634178.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4363..5490
                     /locus_tag="ACF3UE_000723"
     CDS             4363..5490
                     /locus_tag="ACF3UE_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3634179.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5690..6130)
                     /locus_tag="ACF3UE_000724"
     CDS             complement(5690..6130)
                     /locus_tag="ACF3UE_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3634180.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6141..8174)
                     /locus_tag="ACF3UE_000725"
     CDS             complement(6141..8174)
                     /locus_tag="ACF3UE_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFD3634181.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8176..9879)
                     /locus_tag="ACF3UE_000726"
     CDS             complement(8176..9879)
                     /locus_tag="ACF3UE_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3634182.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9973..10923)
                     /gene="manA"
                     /locus_tag="ACF3UE_000727"
     CDS             complement(9973..10923)
                     /gene="manA"
                     /locus_tag="ACF3UE_000727"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFD3634183.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10962..11987)
                     /locus_tag="ACF3UE_000728"
     CDS             complement(10962..11987)
                     /locus_tag="ACF3UE_000728"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFD3634184.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(12196..13065)
                     /locus_tag="ACF3UE_000729"
     CDS             complement(12196..13065)
                     /locus_tag="ACF3UE_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3634185.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13524..15416)
                     /locus_tag="ACF3UE_000730"
     CDS             complement(13524..15416)
                     /locus_tag="ACF3UE_000730"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634186.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15413..17140)
                     /locus_tag="ACF3UE_000731"
     CDS             complement(15413..17140)
                     /locus_tag="ACF3UE_000731"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634187.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17156..17806)
                     /locus_tag="ACF3UE_000732"
     CDS             complement(17156..17806)
                     /locus_tag="ACF3UE_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFD3634188.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18010..18306
                     /locus_tag="ACF3UE_000733"
     CDS             18010..18306
                     /locus_tag="ACF3UE_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFD3634189.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18478..19098
                     /locus_tag="ACF3UE_000734"
     CDS             18478..19098
                     /locus_tag="ACF3UE_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFD3634190.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19190..20356)
                     /locus_tag="ACF3UE_000735"
     CDS             complement(19190..20356)
                     /locus_tag="ACF3UE_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3634191.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20368..20721)
                     /locus_tag="ACF3UE_000736"
     CDS             complement(20368..20721)
                     /locus_tag="ACF3UE_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFD3634192.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20849..21871
                     /locus_tag="ACF3UE_000737"
     CDS             20849..21871
                     /locus_tag="ACF3UE_000737"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFD3634193.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            21890..22051
                     /locus_tag="ACF3UE_000738"
     CDS             21890..22051
                     /locus_tag="ACF3UE_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634194.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(22310..22744)
                     /locus_tag="ACF3UE_000739"
     CDS             complement(22310..22744)
                     /locus_tag="ACF3UE_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634195.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22854..24713)
                     /locus_tag="ACF3UE_000740"
     CDS             complement(22854..24713)
                     /locus_tag="ACF3UE_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFD3634196.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            24714..24854
                     /locus_tag="ACF3UE_000741"
     CDS             24714..24854
                     /locus_tag="ACF3UE_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFD3634197.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(24831..25991)
                     /locus_tag="ACF3UE_000742"
     CDS             complement(24831..25991)
                     /locus_tag="ACF3UE_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD3634198.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26298..27722)
                     /gene="araA"
                     /locus_tag="ACF3UE_000743"
     CDS             complement(26298..27722)
                     /gene="araA"
                     /locus_tag="ACF3UE_000743"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFD3634199.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27738..28436)
                     /locus_tag="ACF3UE_000744"
     CDS             complement(27738..28436)
                     /locus_tag="ACF3UE_000744"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFD3634200.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28393..30054)
                     /locus_tag="ACF3UE_000745"
     CDS             complement(28393..30054)
                     /locus_tag="ACF3UE_000745"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFD3634201.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30272..31672
                     /locus_tag="ACF3UE_000746"
     CDS             30272..31672
                     /locus_tag="ACF3UE_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFD3634202.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31924..33003)
                     /locus_tag="ACF3UE_000747"
     CDS             complement(31924..33003)
                     /locus_tag="ACF3UE_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3634203.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33089..34048)
                     /locus_tag="ACF3UE_000748"
     CDS             complement(33089..34048)
                     /locus_tag="ACF3UE_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFD3634204.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34060..35571)
                     /locus_tag="ACF3UE_000749"
     CDS             complement(34060..35571)
                     /locus_tag="ACF3UE_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFD3634205.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35593..36156)
                     /locus_tag="ACF3UE_000750"
     CDS             complement(35593..36156)
                     /locus_tag="ACF3UE_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFD3634206.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36162..37025)
                     /locus_tag="ACF3UE_000751"
     CDS             complement(36162..37025)
                     /locus_tag="ACF3UE_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3634207.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37039..37935)
                     /locus_tag="ACF3UE_000752"
     CDS             complement(37039..37935)
                     /locus_tag="ACF3UE_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3634208.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38110..39399)
                     /locus_tag="ACF3UE_000753"
     CDS             complement(38110..39399)
                     /locus_tag="ACF3UE_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3634209.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39371..40888)
                     /locus_tag="ACF3UE_000754"
     CDS             complement(39371..40888)
                     /locus_tag="ACF3UE_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFD3634210.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
BASE COUNT        11846 a         8592 c         7097 g        13512 t
ORIGIN      
        1 aaaatttcgt cacattcccc tttttcgtat cctattttaa gcgacttgct tggcataacg
       61 gttcacgttt tgcttgatat tcccgattgt tttcggatca ttgattcctg tgacttcttg
      121 aatcaattgt tccaagtttt catggatctt catttcatgc aattgacggc tttgttcatc
      181 ttcaggatca tagtaattaa aaataatccc cattgttgcc gtcaaatgtg ggcaagtcaa
      241 gttatgttct tgtagttctc tcactggacg tgtaaatctt tcttgataac ctaacttacg
      301 taatggtgtc cgagcgacac gtgtgatcgc atcagagata tttttgtttt ggaagcgatg
      361 aatgattttt tcaatatacg catgatgctg ctctgcatca aacccccatt tggcaatcag
      421 caaacttcct gtttcctgca aaactgattt taattgtgcc acaactaacg catcttgcat
      481 tgcttcatca atggtctggt aacctaacaa ggcacctgta taagcgacag tcgcatgacc
      541 agtattgaca ctaaatagtt tgcgttcgat atatggttct agatcatcta catataaaac
      601 cccttttaat tggatttttt tattttttct ttggctatcg tcaatgaccc attctttgaa
      661 aggttccact tggacgaata aaggatcttc atggtgttgt aatgggacga ttcgatcgac
      721 tgctgcattt ggaaagccga tatatttgtc agtaaatgat gtttccggaa gatatttata
      781 cacttctttt tctagaaatg ctgaaccgcc aatcatattt tcacaggcaa tgatatctaa
      841 agatgttgtg cttccttcct tttctctttc ttggatacct tttgcaatca actcagcaat
      901 aaaaggtaag atattcgggc caatggcggt agtaactaaa tctgcttcag cgatttcttg
      961 gattactttt tctggatttg tttgattgtt gattcctttg acatttttta cagtgatttt
     1021 ttcttttgat tcatctgcta attcgatttc gtattctttt ctttcattta aagcatcaat
     1081 gatcgtgtga ttcacatcta cgaaagtaat ctcaaatcca ttagctgcca aaacctctcc
     1141 aataaatcct cgaccgatat ttcctgcacc aaaatgtact gctctcattt ttctctctcc
     1201 ttaagcaatt gctagatttt ccgttacttc ttctttgctg agcgcgtctg ctagctggac
     1261 aacattgtcc atatcactgc aataaagtgc gatttgctgt acaagttgca aatgctcatc
     1321 tccgactcct gcaataccga acaaaacagt cgcaatcttt tcttcttctt cggtaccaaa
     1381 atctacacca tctggtactt gaacgacaca gatgccggat tttttcacat atttttttgc
     1441 ttcatctgtt ccatgaggaa tcgcgataaa attccccata taaacagata acattttgtc
     1501 tctatctacc atggcatcga tatattcctc atcaacgcac cctgcttcta caagcatctg
     1561 accgcaatag cggatcgctt cttctttggt tttaaaagat cgattgagct cgatcatgtc
     1621 gaatggcaaa ctttgcatgc tgttttcctc ccttaagctg tctgtttcaa atattgtgca
     1681 atcgattcgt atttttgcgg attgaccatg ctgttgactg ataaatgaat ggattgaggt
     1741 gcagccatct gtactttttc cgctaaactt tctttggcta cgatcagtga atcaggttca
     1801 tcttttaaat cttggatatt gacttttctt aacgggatag ttaaatggtt cttgtctaat
     1861 atatctttga gcacggtcat ccccattgtt gctgatccgg aacgatcatc gtggacaagt
     1921 agaatctctt tgatttgttt gatgtttgct gaaagaaact cttctgctgg ctcattctca
     1981 atttcagaaa ctgatgtttt ctgcttgctg cttaattctt gaatgatttc atcatatcga
     2041 ggtgaattca aaaagttttc tactgagaca aaacgcgcgc tcggtgcttt ttgttttgct
     2101 ctttcttgta gttcgacctg agtaacgatc aatgtattcg agtcatctgt cagttggctg
     2161 attgcttgat tggtcaccgt ttgaggcaag tctgcttcct gtactttttt tctcaagatc
     2221 gaagcgccca tcgcacttga tcccattcct gcatcacaag caaaaatgat tttttgtacg
     2281 ccagagaatg tagctccttg aggaatacct tgggcacctt tggaagcttg cttagctgcc
     2341 tttgtctctt gaacagattt ttcgaagtct tcatttgtat ctttcgcatc cgctttcaaa
     2401 attactgcag aaataccaaa cgaaacagct gcggcaacaa tcacgcccaa aataacagga
     2461 aggtaagaat tgaacggtgt catcgctaga atcgcaatga tcgaccctgg agaagctggc
     2521 gctcttagtc cagcatccat caattggaaa atgaaacttc ctgacattcc tccgcctata
     2581 actgataaga ataataacgg tttcatcata acgtaaggaa aatagatttc atggatcccg
     2641 cctaaaaagt gaatgatcat ggctcctggt gctgaagatt ttgctgctcc tttgccaaac
     2701 aaagtaaaag caagtaatac gccaagtcct ggaccaggat ttgcttcaag caagaataga
     2761 atagattttc cagcctctgc tacttgttca gttcccaatg gtgtcaaaat cccatgattg
     2821 attgcattat tcaaaaataa gatttttgct ggttcaataa aaatacttgt caatggaatc
     2881 aaatgggcag ataaaatgat ctctacacct tttgccattg cttgagtcaa tgcatcgaca
     2941 actggaccaa tcgcagaaaa acctaataac gctaatccaa aaccgataag acctgctgaa
     3001 aaattattga ctagcatttc aaaaccggat ttgatccgtt tttggaatag ctgatcaaat
     3061 ttcttgatgg catatccacc aagaggtccc atgatcatcg cgcctagcat cattggaata
     3121 tctgttccga caatcacacc catcgttgca attgccccaa caactgatcc gcggtcacca
     3181 gcaattactt ttccgccagt ataaccgatc aataaaggaa tcagataagt tagcattggg
     3241 cttaccatgg tagccaaagc ctcatttggt aaataaccat ctgggataaa tagagccgtt
     3301 aatacacccc aggcaatcag tgctccaata tttggcatga ccatgcttga taaagtactg
     3361 cctaattttt gtaccctcgc ttttagcgaa atgttgtttt tgggaatcgt ccgttccatt
     3421 ttgtctctcc ctctctcctt ttgatactct aattgtatcc gcttactaaa aagagaaata
     3481 gtcgtacttt ggcacgaaac tttgtgccaa aggtttgagt atgtcagcaa aataaaaaga
     3541 tttcggtatc agaaaacttc aattttaaat aaaactgtta ttttaatttt tttataatat
     3601 gcaaacaata acttttgtta gcatttaatt tagatgtttt ccattctatt atgttattaa
     3661 attttatatt ggaggcctat ctatgacatt actgatcaaa aacatgaaca tgaaacgtgg
     3721 taaaaaacgt gtgattcgac aattgaatct tttagtagaa tcaggagaag tagctgcttt
     3781 gattgccccg aacggatttg gcaaaacaac tttgctgaat ggcattgccc aactgctgcc
     3841 aacaacttat gatcaattgt cccttcacaa catctctcct actgcttata cagattatcg
     3901 ccggtctttc ttttttctag aatcaacgaa tcagttatcc gactatctat cggctgttga
     3961 ttatttgact ttgatcaaat actattggca gagcaaagta gaatgccaaa ctgttttcca
     4021 acgattgaag atgactgagt accttacttt gccgattgga aaaatgtctc taggaatgaa
     4081 acaacatgtc ttgcttgctg cttacttgat cagtgattca tctgtcatgt tattcgatga
     4141 accgttgaac ggattagacc caggaagtat tgatatcttg aatagcctca tcagacaatg
     4201 gcagaaagag gggaagacga ttcttctttc ttcccacgct atcgcgaata tccaatcgat
     4261 ttgttctaaa gcatgttttc taaaaaatgg agaaatcgtc acagaatcct caaatatgga
     4321 agagatttta gctatttatc gtaaattata tgaggtgtaa ctatgtcttt acttacattt
     4381 gaacgcaatc tcttactaaa aaacaaagta aactttttat ttcctctatt gttggtcgtg
     4441 ctctttgcat tcccactttt ttttgatcat aaacttgctt atacagaatt cgatgaactg
     4501 aatcataact atgaagagat gcaacgtttg attgaaacgt tgaaagaaga tgagaatgag
     4561 aaagaatttg tggaaagttt agagaaaagc aacaaactga tcgaagcaat cttacatgca
     4621 aaaaacacag ggaatgtcca gcaaatggtc gaagcaactt atcattatga aaaagatata
     4681 ctggatcgac tgatttctgg tcaaagacaa ggaattccaa tcattgaaca acaaaaacgt
     4741 gtcgagttgc tccgttatat gaaagaacat cagatccaaa gatattctat ttttgacttg
     4801 ccagcgcatc tccctttagc aaattactac gaaaatattt tttcaggaat gatttctagt
     4861 tttttgattt tatgtataac cgccttgttt ctttcttcca tcatctctta tgaaaaaaga
     4921 aagcaggtaa tctctctagt caatctatta ccggatagta tggtaaagaa acatagcatc
     4981 cgttttacca tttattatgg tgcagctatg ctaagtctcg tgatgccatt tttgatcgtc
     5041 tctatactag taataatcaa aaatggtttg ggagacttcc gttatcctgt aggaacgatc
     5101 attggtcagg agatacgaat ccttccgatg tatgagtatc ttttccagag ctttctgttc
     5161 ctgttgttgt gggtgctctt tttaagtaca atcagttttc ttctatctgc tttatttgaa
     5221 cattctctag tcaatctttt aggtacactt ctttgtcttt tcttagcaga gtatcgcttg
     5281 ttttcttcga ttggatggat agaatcaatc agtcattact tgccaacttc ttatgttgat
     5341 tttcaaaatg tgatcatagg aggagatatt ttctcgccac tagcttcaga acaggttact
     5401 ttcatgaatg gtatcttgac acttggtata tggagtatcg ttttattatt cataggtatg
     5461 ggcactatct atataaaaaa gagctattaa aacacaaaaa taataggggc ggtgacaaaa
     5521 accttgtcac cgtcccctat ttcaaataaa cggttttcta gaataaatag ttttcaaaag
     5581 cttgcatccg cagtaataag aacctcccaa caaaaatagc tcctcttatt tttatcttgg
     5641 ttgaagttat tacttgatgc aaggcagctt tttttactgt gaacattggt tatatatgtc
     5701 catgttcaaa aatcatttgg acttcttcaa tggttttcgc atcactgagc gccattactt
     5761 ggtcgatgtc tgaacagaaa aaggctaaat cttggagcac cgctaactga tgttcttttt
     5821 ttaaagccac tacaaataag agtgtcgcga tttttggttc ctcttttgtt ccaaagtcca
     5881 caccatcagg cacttggact aaatagattc cttcttctac tacttcttca tctttgtcag
     5941 tcccatgtgg caaggctacg aaattcccga tatagacact cgctttttct tgtctttcga
     6001 tcattgattg gatatatgcc ggtttgattc ccccttgttg ggtcatccac tggccgatct
     6061 cggtcaacgc ttctttccaa ttttgatagg attgatcgag caatattttt tctgctggta
     6121 gctgtatcat cttttcacct tcatttcttt atttcttcaa tcaggatttt cgctaacaac
     6181 tgataaacga tttctttatt tcctgagcgg aagatctcgg tgttcaagtc attcatgatg
     6241 attgctccac tgatctttcc taaaagaatc ccgtcttttt cttggattgg cgaaggcgcc
     6301 agcataacta acatacggga caaatcgact ggctgtctat ccatcccttc aatggtcaac
     6361 ggatgtttca aattgaaaat acaaaagatc ggtttagaaa tcaatgagct ggatgtatgg
     6421 aataacccca tatttgtatg aggaataccg ataggtgctt gttcatatcg cttaagcagc
     6481 cggcgatgaa ccacctcttc atccgttact agtccttcag gaaaataagg aaataagctg
     6541 cgaatcgttt cggaaatcgt ctcaggatta tccagttctt ggataaaaaa acgaccgagt
     6601 aattgattga tttgatccat gaaatgcatt gtttcctcat aagtatcttc tatcatccac
     6661 tcgttattgc tgttatacgt aattttttgc ctttttttct tctcaatatg cgaaaaagct
     6721 tcttttagct gcttgacttc atcttctagc agtagcgggg agactaaaat atattttcca
     6781 ccgtatcctg gtaaaataga tgtagaaata acaacatcat attcttcttg taaatcgatt
     6841 ttttttaaat cagcaatccg atagaaatga atttgttgga tgaagggaaa ataccttttc
     6901 aatcgtagtt ccaacatgct agtagaagct aatccacttg gcgaaaatcc tgcaatactg
     6961 atattgcttt ctttcggact tcgttccaat gaattcgcaa aatgaaggac catataagcg
     7021 atctcttctt cggataattt tttttcttga aaaatccgct ctactgcttt acggattgca
     7081 ttcgcaactt cctcgtattg aaccatgatt ttttctaaaa tcggattggt cagtgtctct
     7141 tcttgtaaaa cggctcttga aaacacacca gataaatgag tcaacagcat tttgtacaaa
     7201 gtttcatctt cataaaaatg gacattcgtc tcttcactta cttcttgaat cagttgtttt
     7261 actaaataag caagctgtgt atcgaacgtc tcttcaaaga aattctgatc aaatgagttc
     7321 gtgaagtcat ttaataatcc tgcaaaaaag acgatctcat ttactggata aagttgtttt
     7381 gtctcagaag cgatccgtga aaacaatcgt ttagctgtct gtagtaattc tttgtttgcc
     7441 agactattat atgtctcatt tgtcagtaaa tgatttttag tcacacgctc catcgtcaat
     7501 gtcagcatca aaaccaaatg ttcaagcttt ctatcactta gattggtctt tttttggatc
     7561 aattcttccc cgattacttt gcgtgcaaga gatagatgtt gcggatcaac gaatcgaaaa
     7621 aaataattca gtgatgcatc gaaagaaata ctatgaaaaa gttcatattc attgatttct
     7681 aattctaata cattcgctgt cagaagccgg cggtattttt ccggtccttc gatctcgtat
     7741 ccctggttcc gaatgatttc caaaggcagt tggcgaatac tttcttccaa ctgtttgata
     7801 tctgcataaa aagtggtatt actgatgcga tatgattcca tgaaatgagc aagactcaac
     7861 ggctctgtcg tcagtaacaa ctcggctaaa atcgcgtgtt gtcgtttagc agtggataag
     7921 tcattacttt tcccatctgt attttctttt aattgctcta atacttcttc tgatgcctca
     7981 atgacaaatg agcctctagc tgcttttttc aaagaagcat ttaccgattt caatgagact
     8041 tcaagattat ctaattcgcg gtaaatagtc cgtttactga ccttcaataa attcatcatt
     8101 ttttggatag atacaggtga cgggctactg agaaattctg ctaataattg tttttctctg
     8161 ggcgataaat acatcttata tttctccctt cacgagtttt tcgtattcat tcgtagctac
     8221 ccaatgttca actagaacta gccgagggat cttttcttct agctgttcag ttacagctag
     8281 ttctctttgt gcgatataaa tcgtttcttc ttggattttg attttttcta ttgattcttt
     8341 tgagataaca aactgttttt tcgctttttt tgctaattga cttaaaatcg tcatgcccat
     8401 agtttgtgag ccgcgtctgt tgtttttata caaaaataca atattagcag gcgacttttt
     8461 ttgttctgtg atatctgcta tctctttttt ttcttcccgc tttggaaatt ggatcgcttc
     8521 ttttattcgt gacagcaaga tatctgtttc caaaaagtga tccagtacat agatttgact
     8581 ttgaggtact ttttctcttg caagacccgc tagttcatgt tgcacgataa ccagctgatt
     8641 tacttggtta ttcaattcat agatagagct gtatccgaca gaaagatcga ttttttctgc
     8701 tgctaatttc tttttcagca gggcggctcc catagcactt gatcccatac ctgagtcgca
     8761 agcaaaaatg acggaatgaa tgatagatgg ttccaagatt tctccccttt ctttgaccgt
     8821 tttgttctct ttttctttat ttggtaattt caatagtatc gctgcacaaa tgaaggtcac
     8881 aaatgtactg attgctatcc ctatacttac cccagctagt tgtggataag gcgcattggc
     8941 aaaaatcacg agtagtgacc caggcgatac aggtgcagct aatcccgtat ctaaccattg
     9001 aaatatcaac gtgccgcttg ccccaccagc cattacagct aaaaatagat acggtcgcag
     9061 caagacaaat ggaaaataga tttcgtgaat cccgccaatc gcatggatca tcaatgctcc
     9121 actcgcattt actttttcct gtttttctgc aaaacaaagg atagaaagta agatccctaa
     9181 accaggtcca ggatttgcct ccatcaaaaa taaggaagag tacccgactg tttgtgagaa
     9241 ttcgattcct aaaggtgtca atacaccatg attgattgca ttattgaaaa atagtacttt
     9301 tagaggttct aagatcagac tgacaagtgg taacagattc attgtgacta gccaagacac
     9361 aacggaggcg agcaacaagt gaacactatt taaaactggt tcaataaaaa cgattccaat
     9421 tatacaaata acgctaccag tcagtcctac tagtaggttg ctgacaagca tttcatatcc
     9481 agccttgaat ttcacgtgga atctagaaac aaattgttca tatacgatgc cggcaagcgg
     9541 cccgataatc atcgctccta cgatttgtgg agcattggaa cgagcgatca accctaaaga
     9601 agcaattgca ccggcgactg cccctttttg tccccctacc gatttcccgc ctgaataact
     9661 gatcaagatg ggtaaaagca gctggatcat ccaatggcat acctcttcta atgtggtgtg
     9721 caaatcgcca gacacacctt ttgttgctaa tgacaagatt ccccaagcga taaacagact
     9781 tagatttggc atgatcattt catttaagtg atgtccagct tttctcagtt gtttcataga
     9841 cacgcgactg ctgttgtttg ctttccattt gtattccatc tttttcacca tacttctatt
     9901 tattgatgga cggattttat gtagaaaaag cagcaaacga aaaaccgtct gctgctttca
     9961 gctatctggg aactatttgc ctggttcagt cgcaatgatt gctagttcac cttggaccgc
    10021 ccactcagaa acgccatttg gaataataca gcttgttcct ttttctaatg gatatgtttt
    10081 tccgtcaacg acaaggtctc ctgctccttc gattaccgtc atcaatgtat aaggggcttg
    10141 ttttttgaaa gatgtgattc ctttaatatc ccactcatat acattgaaaa actcagtttc
    10201 taaataagtg acgatcgatg aattcccttt tcggacttct ttgatttgta attctggtgt
    10261 tttcgcaggg acagttgtta catcgatcga ttgttggata tgcagctctc ttgtttgtcc
    10321 ttgcgcatct tttctgtcgt agtcatacac gcggtaagtc gtgtcagaac tttgctgtgt
    10381 ttctaaaatc atgattcctt taccaatagc atggatcgtt ccgcttggta cataaaagaa
    10441 atcacctttt ttaactggta ctttcttcaa aaggtcatcc cagcgcccat ctttgatcat
    10501 ctcagctagt tcttctcttg tctttgcatg atgaccatag atgatttctg caccaggttc
    10561 agcatcgatg atataccagc attcagtttt tcctaattca ccttcatgtt tcatcccata
    10621 ggcatcatct ggatgtactt gtacagatag atcatcttct gcgtctaaga tcttgatcaa
    10681 taatggaaac actggttctg aaggatggcc aaacaattcc ttgtgttctg accatagttc
    10741 atctaatctt ttccctttga attcgccatt ttctactaca ctgacaccat gaggatgcgc
    10801 actgatcgcc caatcttctc cgattttatc gttagggata tcaaaaccaa agactgaacg
    10861 taaacgactt cctccccaaa ttttttcttg aaaaactggt tttaaaaaca taggttcctg
    10921 cataattcaa actcctctca tttttcatag ctattatagc attatttcgg taataccgct
    10981 ttctctttca aaaagttttc aacaatttca tctcgacata tgagatactc cgcacgatga
    11041 tcgacaggat gtacgcgatt tgacaaaaat atcaacgctt cttgtgtttt tatatcaatc
    11101 aagaaaaacg tacctgtata accagtatga aaaagaatcg catgaccgtc ttctacatcc
    11161 ttttttaagt cccatcctaa agaacgatag ccattttttt tcggtgtttg atcttgcagt
    11221 aaagaatcaa tcgtctcttc ttctaaaaaa cgaccattac ggatttttcc cttgttcaaa
    11281 tacatttgga caaaagtaat gctgtctttc aaatcaataa agagacccgc gttacctgca
    11341 tgttcagcca aaactcttgc tttcggatca tgagtttgtc cacgcaaaac ctcacccgaa
    11401 ggcagttgtt ctgtgggaac gatttttttg gaaggaaaag gaagaaataa gctgttcatc
    11461 attcctaatg gttccaatac ttgttcttga aagatttcca ctgcagtttc ttggtaaatt
    11521 tcctctagca tcaacccaag aagaatcgta ccggcatctg tatattttac ttcttttcct
    11581 agttgctcac ctggttctag cttcaaataa gcggcgatca attcttcctg agatagctta
    11641 tctctgtttg gtatccatgt tttgatatca gaagtatgtg tcagtaaatg acgcaaagtg
    11701 attgtctgat tttcaaattc aggaagatat ttatgaagcg gttgatcgag ttctatcttt
    11761 ccatcttcta atagacgtaa aactaatgaa gtggttgcaa cgactttcgt cagtgaggct
    11821 gcatcaaaca acagatcttc tgtcatcagc tgcttttcag gaacgacttg ggcaaagccg
    11881 gctgtaaatg tttctacttg attttctttt atgaaggcga ctgctacacc tggataaaat
    11941 ccttcttcca tctttttcaa aataagctgt ttcgtgtgtg gatacatctt tttctcctgc
    12001 ttttctatca gattcttaca gtccaagctt aaagcttaat ctatgaggaa tcaacctttt
    12061 ttacacaaaa aaactgcgcg aaaaaccgcg cagtttcccc cggtatacta ttttctcttt
    12121 ctatctctag aataagcgat agtatgaccg ttcataaaat gacgagacat gcgacaatcg
    12181 ttaagaaaga aaaagttaag cgtcgcatcg aatgtcagtt ttattctttt cttttggctc
    12241 actgacgaac caccattcga ttcctatagc atcatagatt gtgagtactg tgtgcttttt
    12301 gtctaagaag aaatcaactg atagttgctg caagtgagca atcagtcctt ccatgctttc
    12361 agtatcgatc atgaatttca gaaaatcaag tccaatcact tcatctgtag gcaaatcaat
    12421 tgcgcctccg ctagcttctg tcaaaccaac atggaaatct ccttcattca atacatggat
    12481 gccctcttct tcattatgta ccttcaaacc aagtacatga ttaagaaatt ggcgttcttt
    12541 tgttaagtta gtaacattta aatggatttt ttcaaaataa gaacctgttg atagtttact
    12601 gaatttttct tcagattttc ttaataatgc ttcttgatcc attgtttctg gaatttctct
    12661 ttggtcgttc ttattctctt catggtaaat ttccaattca ttctcttctg ggtctacgag
    12721 caaaatcccc atacgtccat gatcttctaa agcttctttg attggataat tcattttacg
    12781 gatacgacaa aggatatctg ccatttcttc tgtgctaggg ataatcaatg aaaaacggtt
    12841 cagctttttg atcaccccca tgtgatcatt cgctctagga ctttcttcca gcagcaacat
    12901 ttcacttcca gcttcttctg ttcctaaaat ggctaattcg ttttcttctc ttttcaaatc
    12961 aaagccaaca acgttcttgt aaaaatcaat cattttatct cggtctttca cccgaatggc
    13021 tacacttttt aaataggtgg cagcccccaa ttgaaaatct ttcatatttc ttgctcccct
    13081 ctacgtcaag ctttatttta acgatggatt cttcttcttt caagcaataa ctttgatttt
    13141 gttaaaaaaa atgtgagaaa attcgcattt tgcttgtttt ttgtaaatta atgagtaaaa
    13201 actcttataa aaagaggttg tgaaaaagct gttctgcatc aagtaataag aacagccaaa
    13261 caaaaatagc tcctcctatt tttcgtttgg ttgggcttat taccgcagat gcaagctttt
    13321 gaacaccgtt taaggaagag gttgtaaaat cagcggtttg acctgagtat tagagataca
    13381 aaacggaaaa atagcttctc atattttgcc gttttttgag ctaataccga aggacagctg
    13441 attgaacacc gtttattcgg aaaaagggac tgtgacacga cttttgtcac agcccctaaa
    13501 aaaaataata aatttgtact attctatgaa gcttcttctt cagaaaactg actgttataa
    13561 agatctgcat agaatccgtc tttttccatc aatgtatcgt ggtttcctgt ttctacgatc
    13621 gaaccatgat tcatcacaat aatgttgtct gcatcgcgta ttgtagacaa gcggtgagca
    13681 acaacgaaac ttgtccggtt ttccaatagg cggttcatcg ctttttgaat cagtatttct
    13741 gttcgtgtat ctacactaga tgttgcttca tcaaggatca ggacatctgg atttgctaag
    13801 aatgcccgcg caattgtgat tagctgacgc tgcccttgcg aaatattgct tgcatcctcg
    13861 tttaatacag tgttatatcc ttctggcaat ttacgaacaa aatcgtctac gtgagcagct
    13921 ttagcagcct caatgatttg ttcgtctgtt gcatcgtcgt tcccatattt gatattgtca
    13981 tagatacttc ctgtaaacag ccaagtatct tgcagtacca ttgaaaactg tgcgcgcaat
    14041 tcatcacgtg aaagatcacg ggtatctaca ccatcgtaac gaatactacc tccagaaaca
    14101 tcgtagaacc gttcaagaag gttgatcagt gtcgtcttcc ctgcaccagt cggacctaca
    14161 atagcgacca tctcaccagg tttgacatcc aagttaaaat cagtcattag caagttatct
    14221 ggtgtgtagc cgaattgaac attttcaaaa cgaactttgt atggtgtatc tttttcttct
    14281 ggaaggccag atttttcatt ggacatctct tcttcatcca acacttcaaa tacccgttcg
    14341 gctgaagcaa ctgttgattg gatagtgttc atcaaacttg caagttgagt gattggttga
    14401 gagaactgtg ttgtatattg caagaacgct tgaacatccc ctaatgtcat gttcccattt
    14461 gcaactttta ctccgcctag tacagcgacg aacacatagc ctagattttt aacgaaattc
    14521 atcaacggca tgatgattgc cgaaataaat tgagctttcc aaccagcggc atacagattc
    14581 tgattttctt tttcaaatac ttcctggtct ttttcagtat gattgaatgt tttaacaatg
    14641 gtatgaccac catatgtttc ttctacttgg ttattcaata aacctaaact tttttgctga
    14701 tctgcgaaaa acacttgtga tttcggcgct acgatcatca cgatgatcaa gcttaaaggg
    14761 atcatcaata acgcgactaa cgtcaattgc cagctgattg aaagcatcat cacgatgacc
    14821 ccaatcaatg tgactgcact agttacaaat tgagtcaaat tttgctgcag cgtgcttgcg
    14881 atgttatcca tatcattgat tgctcgagac atgatatccc catttgtatg tgtatcataa
    14941 taggaaatcg gtacacgatt cattttggct tccaaatcat gacgtaattc ataaactgtt
    15001 cgttgggaaa cacgtgtcat aataaattgc tgtaaaaagt tgaatacagc agaaatcaaa
    15061 tacatcacga ttactgtcgc aatgatctgc gcgattttat caaagtctat cggaaatttt
    15121 gttacttgtt ggccttgttg catctgttga gcgccagcca ttacaccttt gaatatttct
    15181 gtggttgctt tccccaagac ctttggtgtt tggatttgga agatcacggc tgctattgct
    15241 agtacaaata cagcgatgat cgcaaccata cgtttagaca tatagccaaa caatcggcgt
    15301 accgttcccc agaaattttt aggcttttca ccttttacac cgagatttct gccaggtcca
    15361 ccatgtcctg gaccgcctgc tggtccatga gagggacgtg tgtttgtttt actcatgcta
    15421 agtcctcctc tcttagttgt gaatgaacga tttcttgata agtttcgttt gttgctaata
    15481 gttcttcatg tgttcctttg ccaaccagtt ttccttcatc tagcacaagg atcatatctg
    15541 catccattac tgtacttact cgttgagcaa ctaaaacggt gatactttct ttcatattcg
    15601 ttttcaatgc ttggcgaaga ttggcatccg ttttgaaatc caacgctgag aaggaatcat
    15661 caaacacata gatatctgct gttttgacta atgcccgtgc aattgccaga cgctgtcttt
    15721 gtccaccaga gaagtttcct cctccttgtt ccacatggct atctaagcca tcttccatct
    15781 ctgaaacaaa atctttagct tgtgcgattt ctaatgcttt ccaaatcatt tcatctgttg
    15841 catccggctt accatactgc atattgtctc ggatcgttcc agagaacaga actgcttttt
    15901 gaggaacaaa gcccattaat tctcgcaaat tatattgagt catgtcacta atgtccgttc
    15961 catttatttg gatcgaacca gattcgatgt catataatcg agggatcaaa ttgactaagg
    16021 tcgttttacc tgaaccagtc ccccctatga ttgcgacgat ctcgcccgac ttggcttgga
    16081 aatcaatatc ttccaatgca agtttttctg ctccatgata tcgataattg acatgattga
    16141 aggccaatgt tgcgtttttt ccagcaaaag aaactgtttt aggattttca gggtcatgga
    16201 taccgatttt ttcatccaac acttcattaa tacggtcagc tgaagcttgt gcacgaggca
    16261 ccatgataaa aatagcggaa agcatcataa agctgatcaa gatctgcatc gcataagtca
    16321 taaatgcaat cagattaccg acttccaaag tcatatctgc tatgtagtgt ccaccaaacc
    16381 aagtgattgc tacgtttgta ccgctcatga tcaatgtcat cattggcatc atcaatgcga
    16441 cgatcgtatt aactttgatt gccgtatttg tataatcttt attcgctaaa tcaaaacgat
    16501 tttcttcaaa gcgtgtctta tcgaatgctc gaatcactct gacccctgtc aatccttctc
    16561 gaaataccag gtttaaacgg tcagttttct tttgcatact tttgaataat ggaacagcaa
    16621 agtacatgat tccgccgatc aaaataatca ttactgggat gacaactaag aagatttttg
    16681 tcaactgatg atctttttga taagcaagta tgctcgcgcc aatcaacgtg attggtgcat
    16741 tgatcatcat acgtaaaaac atttgtgtaa ccatttggat ttgagtcaca tcattggtcg
    16801 ttcttgtgat caaagaggcc gttccatatt tatcaaacgc atcttttgtc agactctctg
    16861 attttttata gacatccgta cgcaattgct tacccagttt ctgtgattca cgagtagcaa
    16921 aaaatgtatt tgcgatagca gctaagatac tgatcaaaga aaagccgatc atcacaaaac
    16981 ctgtatgcca aatataatcg acatctcctt gcgctacccc tttatcaata atattggagg
    17041 taagtgtcgg caaatataaa tctgccagta cttggatcac catgaaaact gcagctgcaa
    17101 ttgctgaagt caaggagatc cgttttacga tttttagcat ctagttccct tctttctatt
    17161 tatatactcc gtttttcagc caagaaagtt tcaaattgaa ttcactgatt gcttgctcta
    17221 ctgagtaatc ttcagatgtt gaaaataagc gatacgaatg cgcaattgtt gtaaatacag
    17281 tattcatcac taattggatc agtaattcca attcatgatc attttttact ttcagcttcg
    17341 tccgatcgat caattcaagc aactcttttg catcttgttt gtgttcttta tgtggatcgt
    17401 gaggcgtttt ttggcgactc gtatgaggag cgacttttct tgaggcacgg taatccatgt
    17461 tcataaacaa gttacgataa aaagaagcat tctcgccttc caaaatctca taaatcattt
    17521 tagaaaaata ggattcgaat cctttgaata gatcaccatc ggattctttc attagttgta
    17581 acatatcttt agagctgtca cgtctcattg tctcaaagta ataaaaataa agatcctctt
    17641 tatcttcaaa atactgatag aaactgcctc tagggatatc cgctaatttg acgatattag
    17701 caatcgaagc ttcttttaag ggtactctag aaaactcgat tctcgcagcc tcgattagtc
    17761 ttttttgttt ttctttaggc aaatggaaaa atgtctgtgt cggcatatgg atcctccttt
    17821 ctttcaagat gacacattgt catatgacgc tgtgtcatta taacacctcc tacctgtttt
    17881 gcaagacatt tgcatagttt ttttcattat catccgatac attaaaaaag tgataagagg
    17941 aatccttcca tttgaattaa tgagagttgc ccattaaaat agccacatac taaacaaagg
    18001 atgagataaa tggcccaatc aattagtgtc caagacttca ataaattgcc tctcgatgct
    18061 gacagcatcg ttttagatac aagaaatacc ttagattaca caaaaaacca cttaagccac
    18121 tcgctttcta tccccgctgc tatcttgcca agacaattaa aaaatctaga tccaaagaaa
    18181 ctttattata ttctaagcta tacaggcagg cgatcagaag cattagccga tcaacttact
    18241 gctaatggtt ttcgtgctgt ttatatcatt ggtgggatgg aagctcttca gtcgagtgtt
    18301 gcttgaatat tgcttgttag attcaaaaga ggctgtgaca aaaaatcgtg tcacagcctc
    18361 ttttataccc tgtctttttt tagttattta ttcttcaacc ttatcaatat gacttgatag
    18421 ccttttcttt ttctcatagt tataacaatc atagcaataa aaggagaagg taagcatatg
    18481 gcatctgttt tagtagtcaa aggtcatccc ctaactgcag aagaatcgcg cacagttaag
    18541 gcattgacgt cttttttaac aagttataaa gaaaatcatc cagatgatga agtgactgtt
    18601 ttggaacttt atcgcgatga tattccggaa atcgatgaag aattattatc aggttgggaa
    18661 gcattacgtg ctggtgcaga attcacttcc ttatcagaaa gtcaacaaca aaaaattgct
    18721 cgtttcaatg aattgactga tcagttcctt gctgctgata aaatcgttat cgcaaacgcc
    18781 ttatggaatc taaatatccc aacaaaatta aaagcttggt tcgataccgt caatgtagct
    18841 ggaaaaacgt tccgctatac agaaaacggg ccagaaggat tagtgacagg taaaaaagca
    18901 ctgcacatcc aatctaatgg cggtgtatac aacggacaag actttgcctc tcaatatgta
    18961 aaaggtattt taaactttgt aggcatcgat caagtagatc agctattcat cgaaggaatc
    19021 gattatgacc ctgaccgtgc agatgagttg atgcaaaatg cattagataa agctgctgct
    19081 ttaggtaaat cattttaaaa attgagataa atgcatacaa aagagacaga ggaaaaaatc
    19141 ttcaaagcag catttgtacc ttggatattt tcccatctgt ctctttttgt tattctttct
    19201 gctttttcaa cggattttct tcataaagag aagagattgt tgtgtaccat tcaaaaacat
    19261 gagtaatcac tactttagct gctgcataaa caggaatccc caagatcaca ccgatgattc
    19321 cgaacaattt cccagaagtc agcagaacta ataaaatcgt tactggatgg attgctaact
    19381 gattccctag tactaatgga gagatcaagc gtccttctat tgtctgctct actgcaaaaa
    19441 cgatcagtac tttgatgatc atgaatggac ctgctacaat ggctaaaaag atagccggaa
    19501 tcatcgctaa aaatgatcct aagtaaggga tcaggttcaa aaaacccgca ataatcccca
    19561 acgtgacagc atactctaaa ccaatgaccg caaaaccaat cataaacatg attgccacag
    19621 caaaagccac agttagttgt cctcttatat aagaagaaac ttgactattc atttcactca
    19681 gcacattcaa cgtcggtttt tgcatgcgtg tcggtaaaaa tttgacaaaa taaggtgcta
    19741 attgtttacc gtctttcaat agataaaata agataaacgg catcgtcagc agagccacta
    19801 aaatagtcgc taccgcgccg acaaaacttc caagactctg aactgtactc ttagatatat
    19861 cttggatcat atcgcctgcc gaattcatga acttatcacc tgctgtttcc aactgttcgc
    19921 gaaattggtt gaacagcggg tcccgcaaaa tctcggttaa tttattatca atcgtatcta
    19981 catattgagg gaagttactg atgaagctca ctgtttgttc ctgaatctta gggatgatca
    20041 ctacgctccc ccatgcgatt agtgcaacaa ccaaaacaaa cagcccaatg atactgtaaa
    20101 gccttggtac ttttcgcttt tcaaagtaat caactaccgg attcatcaag taatacaaga
    20161 ttcctgctaa aatgataggc agacctacga ttgctaaaaa ttgccagatt ggtgcaaaca
    20221 aatatgaaac ttttgtaaat aaaaagacga tcagcaatat taacaataca acaagtaagg
    20281 ctgtgactac ttgattattt aaaaaccagc gccaaaacca cgataccggt ctgttcttct
    20341 tattttttcc ttccataatt cctcctgtta gttataaaaa atttggcttc ccaaaccaat
    20401 agcaggcagt ctatgcggat gaagatagat tccatttgca atttgtcctt cttctggaca
    20461 agcatcaaaa atcaatgata cgtgagctac tgtctctaaa ttcccattgg ccatcggacc
    20521 gacataatcg atcgtatata cctgatcatc aaaagcaatt gttccgcctg ctttcaaaga
    20581 aaaaggttcg tcttttgata cttcttgaat caccgaatat tttcgtaagg cagctgttgc
    20641 tgttttatcg aacaaaatca gcatgggttc ttccttgttt attgcttctg tcccaatttc
    20701 tgtaatcttt gcctgaatca ttgcactctc tcctttaatt gctttcaaaa acagtataac
    20761 acattctcat tctttagccg tgtggaataa ttatgtgata gaataaaaac gaaaactatt
    20821 tcattacaat taggaggaat cagctcatat gatcgaaaag ataattttag gaacctatac
    20881 gcgtcgcgaa agtaaaggaa tctatacgat cgaccttgat acagaaaaag aagaattagc
    20941 caacctttca ttagctgttg aagaaaatag ccctacctat gtagcaaaaa gtaaagctgg
    21001 caatctttac acagttacta gtgtggatgg attaggtggt gccggtgcgt acgataagga
    21061 ttttcatttt ttgaatgcgg taacagagtc tggcgctcct ttgtgttatg tagcggttga
    21121 tgaagcacgt caattactat acggggcgaa ctatcataaa ggtgaagtaa atgtctacca
    21181 tatattagga gatggcgaac tgaaagcagc agattcaata ttccatcaag aagcgacagg
    21241 tcctcataaa aaccaagatc atgcgcatgt ccactatacg gatctgactc ctgaccaacg
    21301 attagtcgta tgtgatcttg gtacagatcg tgtgtatact tatgatgtgt ccgaaaacgg
    21361 caaattgaat cttgtaacta ccttcactgc agagccagga acaggccctc gccatcttgt
    21421 ctttcatcca aatggacaat tcgcttattt atttggtgaa ttagacagca cagtccgcgt
    21481 gctttcttat aataaagaaa caggtgcttt tgaagaatta cagaaaatat cgaccttgcc
    21541 agaagaattc gacggtgaaa atggaggggc agctatccgc atttcaaatg atggcaagtt
    21601 cctttatgct tctaaccgag gacataactc gattgctgta ttcgcagttt ttgaagatgg
    21661 ttcccacatt caaaacaagc aaatcatctc aacagaaggg gattttcccc gcgatttcgc
    21721 actagatcca agcaataatt ttgtcgtgtg tgccaatcag aacaccgata atctgacatt
    21781 atatcgccgt catcctgaaa caggattact ggaattactg aaaaaagatg tctatgtacc
    21841 agaatgtgtc tgtgtttatt ttgatcgtta gtaagaaaag gagaatgaaa tgaatcagca
    21901 agacgtatta gacagactac gggaagaact aaatattcct ttctttgatg ggaaaatcga
    21961 agataaagag tatagcgaag aggaatatca gaaactcaaa gccgatttac agaactactt
    22021 tgaacaatat gtacagaatg tagaaaacta atcagctttc catactatct gaaaagaaca
    22081 tcaggacaag acttttccgt ctatcctgat gttcttttct acaaataaaa aaccgccgag
    22141 atggttagac tcgacggaaa aggagtattt actcgatttt gagtaagtac aaggttgttg
    22201 ttggttatag gtatgtcatt atcataaagg attttgatca ctctatcata aaggtaatat
    22261 tacatttata ttagataact ctagttttta ttgttatcaa agatttcttt tattttttca
    22321 acaacaaatt agtcattttt tggatggcag ctgtcaattg gtctgtcgct tggtcttgtt
    22381 ttgcttcaga tgtattgaat agatcttcat ctacccctga ttcaagatcg atactttgga
    22441 tcatttcttc acagcctgct acatatgaaa gataagcttt ttcaaaattt ttatgaatgc
    22501 ccattgcttt tgctggtgga cgcaaagtac tgactttctt aagcattgcc cgatattttt
    22561 ttgttccttc ttcaaataac aggatgatct cttcaagagt cgatttgtcc agttcacttg
    22621 tttttccttc atcaattgcg tttctgatca cttcatattt cggatgcatt ccttctccga
    22681 ttgcttctgt ttccttgacg atttgatcga tggactgcac ataatagcca atattcggta
    22741 acatgttcgt tttcctactt tctccattgt tgttattatt tattctactt gtttttatcc
    22801 tcaaatgaca agtacttgaa aaaatttaat ggtttctata cagctcgcca ttcttattcg
    22861 tgctcaaaga aaccatctgc taaactatat tgtttccctg cgacaatgtc atattggatc
    22921 aattgatatt cgtcgtaaat ctcttgttgc gagcgattga attgcgcttc tttataccac
    22981 tgtccgtttt gatagtacag ttctcgttca aacgccggaa gttcctgttc taatgataaa
    23041 agcagctgat aaaagccatt tgttgtctga ttcgtctgtt ccattagatt cgctgcaaaa
    23101 taaaacggac tggtgattgc atcgtgagtc gtttgctttt ctaattctcc tttactgtcg
    23161 aacataagaa attgtgtttc atgcaatgtt tgtttgtcat tttttgcttg gatcgtatct
    23221 gaatagatcc ctggaagatg atccccccaa aaaacaacta aagtccttct agaaagattc
    23281 ttcaattctt ccgtgaactg cttcagtgcc gtgctgctat aggaaatatc ttgcagataa
    23341 ttctctaagt caagtgtccc acttccatct gaagtttttg caggatagtc tagattatca
    23401 tactttccat cgtagggcat atgtgtctgc atcgtgacta aatgaatgaa ctgaggtgtt
    23461 ttttcttcct tgagaagtgt cattacttct ttgtaagctg actcatcaga aatatatgga
    23521 ttattctcta tcgtatccgt ataggtcatc gtacgctcgc tgatgaactg gtcaaatcct
    23581 aatgtctgat aaacatcctc tcttttatac atcgaagtat tgtatggatg gatcgctgtc
    23641 gtctggtatg attgtgcgtt taacgctgaa acgatagaag gaagctgatc catttttggt
    23701 acaagcatcg tgtaaggggt ggtgagttgc gcattaaata acgccataga aaaaccagtc
    23761 aatgcttcaa attcgatatt tgctgttcca ccgccatagt tttgagaaag catattgcca
    23821 ctatatgttt gatcagctac ttcataataa tctgccaatg gctcaccaga tacttctacg
    23881 ccgtttaatc gactaggatc tgagaaactt tcactcatca cgaacacgat gttcggcgac
    23941 tcttcctcta cagttttatt tttttcatcg gctagcttct ggtatttttc agtgatttct
    24001 ttgatctttt ctttcgaata tccttcaggt tcatccattg gttctacctt cagattgtac
    24061 aaaaacccac cgataaaacc agtgttatag tagttcattt tctggctgta aggtatccat
    24121 agtgccgttt tattatatgc ttttcgcaac aaattatcgg gattgttgaa attactgata
    24181 taccctagca gtccaattgc cacaagcagt gtcgttaatc ggatcaattg gaatcgcctt
    24241 ccttttttca ggcttcgaaa catgtaccag caaaacaatc ctatcacggt tcctgcggca
    24301 gctaagatca ctgtaaacag catagtgccg gtcatatctt tcagcaatcc gatttcagtg
    24361 atcatcttca aatcgtctgg ataaatcggt tcttgccgat aactcatttt catataattt
    24421 gcaaaaccta atacaccgat ggctacgaca tacgtaaggg aacctaaagg gacagatcct
    24481 gctagtgcaa tcagaaaaat aagaataatc agcaagacga gacaggctaa gaagaatttt
    24541 tccgtatgcc aagaaaaagc aaatttcaac gcaaggtcta cggatagatc attttgacac
    24601 cactgcaaaa ataaattact aaaaacaaca agaaaaaaga tactgatgat tgctgctgtt
    24661 ccttttaaaa tctttttctg tttggtcgaa agtctgctta tatatctttt caaatgcttg
    24721 ctccttcatt tctatcaata aaagaatgtt gcttctctta ttttagttgt acgaaattcg
    24781 aaagtaaaga acggaaagaa gaattaatga aatccaaata ttctctttct ttatggcctt
    24841 tctggtttct ttaataagcg gacctttcgt actccagaaa ttttttctag ctgttgtttc
    24901 acttgattga gctgttcaaa atcagtactg tctatgtcaa tcaatatgta gacatgctca
    24961 ttcttatggt tacgcgatat atctgcgatc gctagctcgt tctcattcag cagagaaaat
    25021 atctctgcta atatattggt tttcttttga taaaatatag tgaatcgaaa cggcgcttgg
    25081 aaaaacattc gtgcggatgg ataattgacc gcttctctaa ccgtaccgaa caaaagataa
    25141 tcttttaagg cttcaactgc caaacgtccg ctgtctgcca aagcttcctg agtcgatccc
    25201 cctagatgag gcaacataag tatacggtca ttttctaaga actcttcttc tggaaaatca
    25261 gtcaagtatt tagccagatg ttgtttttcc aatgcttgca taacagcata tttatcaaca
    25321 atttcacttc ttcctacatt gataagtaca gcatcttttt tcattttttc tatattcgcc
    25381 tgatcgatca atccttttgt atcttctgtc aacggcagca tgactacgat gtaatccgag
    25441 gtagaaagaa ctgtttctaa atctgcttgc cgaacataat ccaactgggc atcgcggata
    25501 gaataaccca agacatccat ccctaagcta tagcaactta gcgctacttt tgtgcctatc
    25561 gctccaagac caagaagacc gatggttttg ccttgcaatt ctcgtcccac ataagcactt
    25621 cttttgtttt ctgcctgttc taaaatatta ggacctgtta gtgtttgtac catacgactt
    25681 gcttcgatta tcggacggga agataagagc aaacagcaca aaacaagctc ttttactgca
    25741 ttagcattta cacctggtgt attcatgacg atcgtcccgt tttcagaagc tttttcaacg
    25801 ttgatcgtgt tcaccccaac accagctctt gaaattgcta gcaaatctgg tgtaagccat
    25861 tcatctttca ctttcgtact acgaataact attccttcgg ctggcaaatc atctattatt
    25921 ttgaaatatt ccccttgtaa cttttctatc tcttgttctg gaatagcatc aatcaaatga
    25981 acgtgataca taaaaccccc tccttactaa caagtatctc gaaatttctg caattagaca
    26041 actgtttacc atttgacttc ctagaagcaa aaagagcagt tagagcagag taggctgagt
    26101 gataaaaata aggctatgac aagttactgc cataagcctt attttcgaga gcaaaatatt
    26161 gagggtgaga tatcttgata aatggtgttc cgttagctga cattgataat aagactaaat
    26221 ttcaaaaaag ttgaaaagca aatttcgtca atctcttctt atttcttaaa actaagtggc
    26281 tttttcacaa cctcttttta tctaataacc actgtttcca actcaactaa ttttgcccac
    26341 gtttcaattt gatctgttgt tagatttagc gagacaacgg tatgatgacc gccacctgcc
    26401 tgaatccatg aatggacacc ttcatggaaa ttcggtttag ttttccataa cacacgtgca
    26461 acaggtaaat taggtgcttc agtcgttggt tcaaaggctt ctacttcatt gatcagcagt
    26521 ttataatgcg taccgaaatc tgccatcgat acgactaccc cttctcctgc tttcccatca
    26581 aatacaagac gcgccggatc ttctctatct cccattgata aaggagaaac aacgattctt
    26641 ggtttcgtcg cagcaagcgt cggatctact tccatcatat gggattccaa gattgcttct
    26701 tggccactag ctagctcgta agtataatct tccatgaatc ctgtatcttt ccctcgagcc
    26761 atgattttca gcaaccgatc aatcgctgca gttttccagt cgccttcccc agcaaaaccg
    26821 tatccttctg ccatcaaacg ttgtacagct agtccaggta gttgtttcat tccatacagg
    26881 tcttcaaaat tagtcgtaaa agcgttatag cctccttctt ctaagaaacg gcgaataccg
    26941 atttcctgct gagcttgtac ttttacatgt tcctcccatg tcttttcttc ataatcacca
    27001 tagtcgaagg tatacaattc cttgtactct tcaaataatt gatcgacttc ttcgtctgat
    27061 acgcgatcga ttacttgtac aagatctccg ataccaaaat aatcaacagt ccaaccaaat
    27121 tgaatctgtg cttccacttt gtctccttct gtgacaccca cgtttctcat gttgtcacca
    27181 aaacgagcca cttttattcc aaaactttca ttataggcta ctgcaacatc catccaatca
    27241 gcaatctctt tttggatctc aggtcgtttc cagtagccaa cgacgatttt attttgttta
    27301 tttaatcgag cattgatgaa cccatattcg cggtcaccat gagcggattg atttaaattc
    27361 atgaaatcca tatcgatcgt tttccaagga atgctttcgt tatattgcgt agctaaatga
    27421 agcaatggtt tttgtagaag ctttgtcccg cggatccaca tttttgctgg tgagaaagta
    27481 tgcatccaag tgatcacacc tgctacttct tctcgataat tgacctcttt catgattttt
    27541 gtgatcgtat cagcagtaac tgctaattct tgaaggcgga ttggataagg caattggcca
    27601 ttttcattca gttcatcgac catttcttgt gcatgtttct ttacttctcg cagtgcttct
    27661 tccccatata aatgctgtga tcctacaaca aaccaaaatt ctttttctcc aatattcaac
    27721 ataattagcc actcctttta tttgttttgt ccgtaatacg cattttttcc gtgttttcgt
    27781 aaataatgtt tatctaaaat ccgttgaggc agctcttctg aaaatgaatt gagctgtctg
    27841 gtaaataaat tcatcttgca tacttcatct agtacgactg cgttcattac cgcactttgc
    27901 gcatctttcc cccaagtaaa tggaccgtgt ccgtgtaaaa gtacccctgg aattgctaag
    27961 ggatcaattt tgcgttcttt gaatgtttct atgataactt ttcctgtttc atattcgtac
    28021 ccgctgtcga tttcctgttg tgtcaaaaat cgagcacaag gtaccgatcc ataaaaagta
    28081 tctgcatgcg tcgtccccat cgcaggaaca tccaatcctg cttgtgccca gatcgtcgcc
    28141 catgtcgagt gagtatggac gattcctccg atttgaggaa atgaacgata taaaacagca
    28201 tgagtaggcg tatccgaaga gggattgagt ttaccttcaa tgatatgatt gtccaagtcc
    28261 acaacgacca tgtcgtctgc tgtcatctct tcataactga ctccgctagg tttgataacg
    28321 aaatatcgtg tttcaggatc aaaagcgctc acatttcccc atgtatattt gacgagtccg
    28381 tgtttaggca agtcaagatt tgcttggtat acttcttctt tcagttgttc cagcattttc
    28441 tatcactcct ttttcttgca attgatgaat cgctgttttt tcaatgtcga tcccctcacg
    28501 gtaacgtctc ataaatatct gatagcctgc tatttcttct gctgaaggtg tgatggtgat
    28561 tccttggtct tgtccaaaca cgtcttctgc caagaagttt tctaaagact tcccatgtcg
    28621 atccatcata taggctgcta ataacgcgat tccccacgct ccaccttctc cggctgtgtc
    28681 catcactgta actggtgcct ccatagcaga tgctagaatc cgctgtccaa cttctggtgt
    28741 tttaaaaatc cccccatgcc ccactaaacg atcaatttgg acattctcag atttcaatat
    28801 atccattccg attctcattg caccaaaagc actggctaaa tggatccgca tgaaattcgc
    28861 taaatcaaaa cggctacctg gtgtacgtac aaataatggc cttccttcat ttactcctgt
    28921 aatgttttca ccggaaaaat aaccataaga aagtaatccc ccgcaatccg tatcgccttc
    28981 tagcgctttg ttgaataata ccgtgaataa tttatctctg cttatctcca tacccaaaga
    29041 attggtaaat tcttcaaaaa tactgaccca agcattgata tccgaagagc agttattcgt
    29101 atgaaccatg cctactagtt ctcctgaagg tgtagtgacc atgtcgattt ccggatggac
    29161 attttctagt tctttttcta atacgatcat agcgaaggcg gaagtaccag ccgaaatgtt
    29221 ccctgtccgt ttggctacac tgttcgtagc gaccataccg gttcctgcat ccccttctgg
    29281 cggacaaacc gggattcctg gtctcaaatt tcccgtaggg tcgatcagat aagcccctga
    29341 ttcgcttaac ttgccagctt cttctcctgc tactagaact ttaggcaaaa tgtgatccaa
    29401 gtcaatcgct acgtgcgctt tttcgattaa ctgaccaaaa atatttttca tttcttgatg
    29461 gtaggttttc gttgaaggat cgataggaaa catgcctgat gcatctccta cgcctagtac
    29521 tttctcacca gtaagctgcc aatggacata acctgcaagc gttgtcaaaa aattaatttc
    29581 tttcacatgt tcttctttat tcaaaataga ttgatacaaa tgagcgatac tccatctctg
    29641 cggaatattg tattgaaatt tttccgttaa tattcgttct gcttcttcag tgattgtatt
    29701 tcgccaagta cgaaatggta ctagtaactg ttccttgcta tcaaatgcta gataaccgtg
    29761 catcattgca ctgaacccaa tcgacccgat tgtcgtaaga ttctcgccat agatttcgaa
    29821 tacttctgct gccatttttc ggtaactgac gcgcagtcct ttccaaatat cttctaatga
    29881 ataggtccag ataccatttt ctagtttgtt ttcccactca taactaccag cggcaatagg
    29941 agtaaaagat gaatcaatca atacagcttt gatcctagtt gatccaaact caatccctaa
    30001 agatgtacga ccatctatga catctaacat actttgcgca tttacttcct tcataatgat
    30061 ttaactccct ccttctcgtc aaacctgatc aaaccgtctt tttagtagcg cttacaatga
    30121 ttattgtata cttttgtacg tacatgtcaa gcggttattt acaagaatac aataaaaaac
    30181 acttgttttg tacgtacata agttataaaa tgaaattgct tacaaaatct gatcaaccgc
    30241 cttctcgaaa ttctagaagg agagaatact tatgaaaaaa gaaaaaaaag tttcctcatc
    30301 gtttatttat ttttttggcg catttggcgg cattctattt ggatatgata ttggtgttat
    30361 gaccggcgcc ttaccttttt tacagcatga ttggggtttg gcaggtaaag cttctttgat
    30421 aggatggatc acgtcttcgg tcatgttagg tgcgatcctt ggcggctctt tatctggtct
    30481 tctttctgat aagcttggac gacgaaaaat gattcttctt tctgcactta tttttatggc
    30541 tggttctgtc ctttctgcat ctgcccctca caatggttct tattttctga ttgcagcaag
    30601 gattcttcta ggtttagctg ttggcgctgc atctgcccta gttcctgctt atatgtctga
    30661 aatggctcct gctagactaa ggggaagatt gtcagggatc aatcaagtga tgattgcttc
    30721 tggcatgctc ctttcctatg ttgcagatta tttgctaaaa gtgttgcctg aaacgatggc
    30781 ttggcgcgtg atgttagggc tcgctgctgt ccccgcgctg attttatttt tcggtgtttt
    30841 agctctacca gagtcaccgc gttttcttat gcaatctggc cgcttggaag aggcaaaaag
    30901 agtattgaac tatattcgga caccaaaaga agctgaacag gaattcgaac aaatccagct
    30961 gaatgtcaaa caagaaaaga caaccggaac ttcttggcat actttgtttt tagaaaaata
    31021 tcgttcctta gtcattgccg gtattggtgt agcagtattc cagcaatttc aaggagctaa
    31081 tgctattttt tactatattc cgctgatcgt agaaaaagcg actgggcatg cagcgagcga
    31141 tgcattgatg tggccgatca tccaaggaat cattttagtt gctggttctt tgctcttttt
    31201 ggttattgca gacaagttca atcggcgaac tttattgaaa ataggcggta gcgtgatggg
    31261 actttcattc atcctaccag ctgttttagg aactgtactg gatgctcata caaattcgtt
    31321 gttgattctc ttgtttttat gtatttatgt cgcattttat tcttgcacat gggctccact
    31381 gacatgggta atcataggcg aaatattccc actagctgtc cgcgggcgag catctggcct
    31441 agcctcttct tttaattgga ttggttcttt cctagttggc ttgctttttc ctgtgatgac
    31501 tgcttctatg tctcaagaaa tcgttttcgg catttttggg atcatctgct ttttaggggt
    31561 tttatttatt caagagatcg taccagaaac tcgtgggaaa tctttagagg aaatcgaaca
    31621 aagtgcatct aaaaaaactt atcctaaacg tatttctatc catcattctt aaagaggttg
    31681 tgacagaagt ggtcagcttc aagaaataag aaggaaccgc ttagtttcca gtcacaagga
    31741 acaatttcaa aaaacagctt ctcatgtttg atgaatattg tgacttgtga ccagttggta
    31801 ggagaacacc gtttagtgga gaggtggtga aagaaacgtt cagccttgag cgatgacaaa
    31861 agctctcaca aacattgcga cgagtaaccg taggagcaat aagaggcggt aaaaacccgt
    31921 ctcttatttt tcgttttctt tcactgtttc ccgttcaact agtacaggtt catagagaat
    31981 atttggctgt gcctgtcctt tttcaatcgt tgtgacgatc caccgtgcgg catcttgtcc
    32041 caacttttct tttggatgcg tcaatgttgt caatttttta ttccctaaat ggcttaaaga
    32101 agaatcgtct gttcctacga tcgataggtc atctggaata tgatagccat tttctgtcaa
    32161 cttatctagc attaaactag ctatttgatc gttatagcaa atgatgccat ctaaagcttg
    32221 ttcttctttc aaccgttgta ctgttttttc agcgattgtt tctcgtgttt ccgtggtgaa
    32281 agtaatgata tcttccgtca aaaaacgcac attatactgt tcacacgcgc tgataaaacc
    32341 tttcatcctg tattttcctt gaagatcgtc gatttttgtg atgaacaaca gacgctgatg
    32401 tccttttttt atcaaatatt ctgctgccat aaaaccgact ttcacatcat ctaaacaaat
    32461 ataagaggca tttaactctt cataagcagc attgatcatc accatcggaa tgccttgttc
    32521 tctcaaagca acataaagtg ctaagtttgg gttatactga ttacttttcg taggctcaac
    32581 gatcaaacca tctaccccat aagcaatcat tttcttcaaa cactctttct ccaattcgtg
    32641 atcgttattc gtactggcta aaagcaatga atacccagat tctcgtaatt cattttcgat
    32701 tcctcggata atcgacggaa aaatataatc agagagatat gtggtgatga caccgatcgt
    32761 ttttgttctg ttcaatggtg ttttttcttt cttatagctg tcatctacat atgtgcccga
    32821 ccctttttct ttacgcagat agccctcatt taccaacaca gcgattgctt gccgaatcgt
    32881 atgtctgctg acgtcatata tttcttgcag cttgaattct gagggaatgg ttgtatttac
    32941 ttcgtattcc tcacgaagga tcttttgttt tatctcttct gcaatatctt gatattttgc
    33001 catttgcctt gccccttttt atttgtacgt acatatatca taacgagtct gcaaggttta
    33061 ttcaagcaaa aatcaaggtt tcttgtgctc ataaggcata cggaacaggt tcaccaaatt
    33121 ctggaaatcc ttgctcattc cacgtaaagc attgcgcgtt cgcgtgccga ttaggattgt
    33181 ctaacggatc ccctttttgg ttcttctctg gtcgagcatg atagatcaaa atatcaaagc
    33241 acccgtcttc tgaaaccgta aacgagttgt gaccaggacc aaattgctta tttttttcag
    33301 aagaaacgaa tactggctcc gataatttat gccatgattc ttttaataaa agattcttgt
    33361 gctcatcagc ccacagcagg cccatggcat agttttcatc tgttgcacta ccagaatacg
    33421 taatgaatat tttcccattg cgagtaagga ctgctggacc ttcatttact gaaaaacccc
    33481 gtttttccca ttcatactca ggtatagaaa ggaggatctg cttccccttt aacgtccaag
    33541 gattatccat ttcggataga taaagattag aattcccagt aatttcagga tcttgttggg
    33601 cccacacata atatagcttt ccttgagaag agaaagttgt tccgtctaaa ctgaaagttt
    33661 cccttttcgt ttttatttgt cccttttcta tccaatctgt attcattgga tctatatgct
    33721 gattttcaag tacgaacatg cggtgatgat gagattcatc acgtatagtt ttatgattgc
    33781 ttgcagcaaa gtaaatatac cattttccat tgatataatg gacttcaggt gcccagatca
    33841 attcactcat cggtccttct tcatgagcct gccatacaat caggcttgca gcatgttcta
    33901 attcattcag tgactttgcc cttcttaatt caatcacttg gtagcctgga accgatcctg
    33961 taaaataata ataaccatct gtatgtttat atacccaagg atctgcccgt tgccgaacga
    34021 taggattatt ataaagtgtc ttcatcataa caaatttcct cacattttct ttattctaat
    34081 tacattccaa gagtattttt ctatccctac atttaattcg tcatgttttt ctattgaaaa
    34141 atagtttatt tcaggtttta ttttttctgg ttcttcacgt gtatttttgt ccaacagatc
    34201 gctactggtt aatgtgtagt gctctccttg atctagcaaa ttgaaatcat gttcaatcgt
    34261 tatcttttgt tgttcatttg tgcgattgat caagaaaata gtcagctgat tgccgttatc
    34321 tacgatcaca ctgtccacat aaggaacatt ttttatcttt tcacaatcat aaacagggca
    34381 aatgatttgt tgtttcaata cttgaccttt agcatatttc gataagtgtt gcatcacata
    34441 ataagttgga ttcctccatg cttgtccttt agcatctgtc agtattaaag gtattgtgtt
    34501 tactaacaat gattgacaac taatctttac gcgatctgcg tgtcgtaaaa tagccagccc
    34561 taatgaacca aataataatg tatcttccat agtaaagtaa caccaatcga tgggactacc
    34621 gacttcaaaa tccctatgtc ttttttccgg ttgggcatgt acattccatt catcaaacgc
    34681 tagatacatt gttttctcac ttctcaaata tccttttaca taatcacaag tagcaacgat
    34741 ttcttcaatt tgacgatcga atcgataagc ttttgcaagg tatgtcgctg tatcatcacg
    34801 ctcattttta ggaggtttag tcaagtcttc ttcatcatac ttatcaatat agttatgcaa
    34861 agctaaataa tctacattct cataagcttc ttctaatgcg atacgatccc attcagggta
    34921 cgatggtaaa cgtggcgtag agcttccaac taagattgtt tcaattgaat catccactaa
    34981 cttcatgact tttgaggctt catttgctaa cctaccatat tcataagcac tcttagcccc
    35041 cacttgccat ggaccgtcta gctcattccc taaacaccat aatttaacgc caaaaggctt
    35101 tttttgccca ttttttattc ttaaatcact ccagaaggtt ccttttggaa aattacaata
    35161 ttctactaaa ttttttgctt catcaattcc ttttgttcct aaattcaccg tgaatatcgg
    35221 tttcgcttgt acatgactga tccatttaaa aaattcgtgg agtccaaaag aatttggttc
    35281 tatacctcgc catgctaaat caattttttt tggtcgttgt tctttcctac ctacagtatc
    35341 cacccaatca taaccagatg taaagtttcc tccaggatag cgaatgacac ctaattctaa
    35401 ttcctttaca taagagagga catcttgtct aaacccgtca ccatcagctg tttcatggcc
    35461 cggttcataa atccctgtat agacgacact tcccatatgc tcaacaaatg agccaaacag
    35521 ccgagaactg atctctccta ccgtaaaatc ctctctgatt tttactttca cttcttcgtc
    35581 caacagcttt ccctaccttt catttcctat agtcaagata atagatacaa gtttccatac
    35641 gccaccagca aagataaaaa taaaaggagg gaaaagaaat atgagcagta caaatcctaa
    35701 taacaatacg caacaaagaa tatttctcaa aaaatcaaaa aatactttcc atgcactttg
    35761 ttcaaaaatt tgtaaaaatg tgatatcttt gttttcagaa atcacatata tccaggataa
    35821 aagaaacatg gaataaataa gtaaaactac atatccacta attgaaagta cgattgtctg
    35881 ttcttctaat aattgattaa caagaaaata aataatgatc gttaacagac taaggaacaa
    35941 gttcttacca aaatgttgct ttattccttg aaagaaaaaa taaatgatat ttcctgatcc
    36001 ctcacctttc cattgcgcca ttacataaaa aacagcacat gtagcaggca cgatagtaat
    36061 aacaggcaaa cacacgatta cccagagaat acctaataag atgtaatcag aaaccacaat
    36121 caactgtcca taaaatttag tctcaactat tttcatcttc ctcactcttt cattccagac
    36181 atagctgttc cttgaacaaa atatttctgt gcaaaaatat aaaccactag taatggcagc
    36241 attgaaataa ccgttccagc cattacaggt ccataaaaag aaatgttctg ccctgtaaat
    36301 aaagctaacc ctgctggtaa agttctcatt tttgaactac ttgtcaatat caatggataa
    36361 agcaagtcat tccaactatt catcagcgtg aaaatcccta atgataaaag agtaggtttg
    36421 ctcaatggca acatgatttt caaaaaaata ttaaactcac ttaatccatc aatgcgtgct
    36481 gcctcttcca aagaatctgg taaagtaata aaaaaggaac gcatcatgaa gataccaaat
    36541 gcagttgtca tacgaggaat gatcaaacct gcataagtat caagcatgcc aagcaaattg
    36601 acttcaataa atagaggaat catgaagact tggaatggga tcatcattgt cagcaaaacg
    36661 aaatagaaca aaactgattt tcctttgaaa cgcatacgag caaatgcata ccccgcaaga
    36721 gaatcaaaga atacagaagt gatcactgtc cctccagcaa aaatcactgt atttttgatg
    36781 taatctaata aagggatcgt tgtccaaacc ttaatatagt tatctagggt atagctatct
    36841 gcaaatattc taggcggaaa tgagataatg tctttttcgt gtttaaaaga agaaataatc
    36901 agccacaaaa aaggaaacgc aataaccaac aatataacta gcatactaat cgttcgaatg
    36961 atttttttac cactaactgc ttttcgacta ttcacagtaa ctgtaatcga gctttctggt
    37021 gccatacagg tttccctcct atttcatttg tttttctttc cgtgacatgt acacattagt
    37081 ggagatagct atagttgcaa caatgataaa caaaaccgaa gacagtgctg atgcatagcc
    37141 caattcataa ggtgctgtaa atcctcgact gtaaatatat tgaacagctg tttctgtctt
    37201 aaattgtggg ccaccagcgg ttgcaacata tacttggtca aacacttgca tcgaaccaat
    37261 cagattcgtt aaaatacaaa aacctaagga gggaacgatc tgaggtagcg taatgttaaa
    37321 aaactgctgt cgatttgttg caccatccat ttgagcagat tcatacaaag agggagagat
    37381 tccctgaata gcagtcaaga gaatcgtcat agtaacacca aaattcttcc aaacagtcat
    37441 gatggctacc gtcggcatag caagggttgg atcgcgaaaa aattgaggga tcggcaagcc
    37501 gacttgtgaa aacaagtaag gaatcgcccc tacattcgga tcaagcaaca tagaaaaaat
    37561 aatcgcaatt gacgtcaatg aacaaataac tggaatgtaa aatgtcgaac gacaaaaacg
    37621 attgaatctg gtatttttag ataatgctac tgctgctaat aaaccaacga taatttgtgt
    37681 tggcgtttcg agtacggtga aatataaaga atgaatcaac gaattaactg ctcgttcatc
    37741 actaaatata cgtgtgaaat tttcaaaact tacaaaattt cttgatgtaa agaaaatatt
    37801 caaatctgta aaactaatag caaatgttcc taaaagcggt atgacagtaa ataataataa
    37861 aactaaaaaa gatggagtta aaaacaaata cgcagcacga tcaggacgat tccaatattt
    37921 ggtgaatccg ttcatatagt ccacctcatc tttcattttg ataaaatata caatcttggt
    37981 ttaaacgaat ctgaataaga tatccgaaca atcgctgtga tttttgcaat aacacctatc
    38041 tgcaaatact aggtcgatca ttcagatatc tgtatcttgc caacagtcta tcctgtataa
    38101 agttctgtac tatttttgca gtaattgatt gatggcatca tctgcatcgt tcatgagtgt
    38161 ctcaggatct tctcctgcta ataatttttc aatcagtgga ttgatgatat cgttattgat
    38221 cgcagagatt tgggtaaaac ctggtaaata tggctctgca tagtccattt gtttcgataa
    38281 ttcagataca ataggatcat tttttacttc ttcatctttt gctactgaat ccaagtaggc
    38341 aggaaaacca ttttcgatac tccatttttt accaatttca gttgtattcc aatatttcaa
    38401 aaactcatag acagcttctt ttttattatt atctgtactt gccggaatgg catatcctac
    38461 gccatctaaa atagctgttt ttttgtctga atcactccct tgtggtaagg tagtcacatt
    38521 ataatcaatc tcgtttgctt tcaatccgtt atttaaccat ggcccattga tttcaatggc
    38581 tagttgacca gcattcatta aattgtccat ttcggcgcca gaaatcgatt ctggaccagt
    38641 cttgtctaca tggatcattt tttggatcgc ttttaacgtt ttaaggttct caggagacgc
    38701 aaattcagac ttagtataat catcgttcac taatttaccg ccatttgcta acatccagtt
    38761 atataacggt gcagttccat ccttattgaa gacaaaacct gatacatttt tactactatc
    38821 agttaatttt ggtgccattt ctgtcaattc ttcccaagta gtaggtggtt gttcagtatc
    38881 taatccagct tgtttaaaca aatcattatt ccaatacata tacatgcctt gtacctgcat
    38941 ggggacaaaa tactgtttac cttctacttc acctaattca atagccgttt ctttaaaatc
    39001 agatttatct actccatcat attcccagaa atcgtctaat ggttgtaccg ctccgttttc
    39061 tacatactgt gcaaaatctg gataatttaa tgcaataaag tcaggtgctt ttttagaaga
    39121 aatcgctgta ggaagttttt cattcaaatt ggcccaagtc atgatatcca tttcaatttt
    39181 gatgttttta tcatttgttt tattaaattc attaacgatt tcttgcaata tttcaccatc
    39241 agatgcagta aacccattcc aaaaagtcaa agtcacttct ttatcagaat cagattctgc
    39301 tgaacttccg ccaccgcaag ctcctaaaat acctgttgca gctaccaaca aagagccaat
    39361 taaccatttt ttacctttca ttttttgttc ctccttcatc tgataaacga catctgacca
    39421 cattccaaga tagcggtttc aataaacaat tgattttccc atcttcagct tttacatttg
    39481 ttgaatgact tggttttact tgttcacttt taggaagatt agttgctttt gtatcaaatc
    39541 cactcatttc agaaaaatca atcactccct ctaatgataa ttcagacaag tgaacagtta
    39601 gattcatttc ttcttctcca cggttaactg caaatatgac aagttctttg tcatttatta
    39661 cggctatact ttctaaatac ggcacttctt caaaatcttc cgtcgcatag tttgctgaac
    39721 gaatttgtgg gcttaacacc tctccttgtc catacacagc agcttgcata aatggataat
    39781 agatcgtctg tctccaagct tctccgtttg tttctgtcct gattggtgca ataacgttta
    39841 ccaattgagc aagacaagca atctttactc tatctgcatg tttcaataaa gtgattaata
    39901 gacagcctaa tagtaatgca tcttcaaaat tatagttatc ttctagtaaa ggaggagcaa
    39961 tctgccaagg cgctgcttgc tcatcttgtt ccgctgaatg ataccaaata ttccattcat
    40021 caaaggacag gttgatctgc ttcttactat gtttcttcgc cttgactgta tcgcacatcg
    40081 ctgtcacttc agaaatgaac cgatccatgt ctaaggaacg tgcaagataa tgagaaagat
    40141 catttttttg gttgccataa tattgatgca gagacaaata atctatttga tcgtacgctt
    40201 gatcaagaac tgttaactcc caatcaccaa atgtaggcat ttgccgattc gaacttccgc
    40261 ataaaaccac ctcaattgaa tcatctacga gtttcatcgc cttagccgtt tcctctgcta
    40321 accgtccata ttcttccgct gttttatgtc caatctgcca aggaccgtcc atttcattcc
    40381 ctaaacacca tgtcttaatt ccaaaagggc tctcttgacc attcgaacgc cttaaatcac
    40441 tccaataagt tcctttagga aaattacaat attcgactaa attacgagct gcatctactc
    40501 cacgagtacc cagattgaca gccatattga tttcggcccc cacatgctga caccagttat
    40561 aaaattcatg aatcccaact tcattcgttt caattgtccg ccaagctaaa tccaaccttc
    40621 taggtctatt tgctatgggc ccaatactgt cttcccaacg aaatcctgac acaaaatttc
    40681 caccaggata tctaatcatg ggaatgttca attcttttac caagtgaatg acgtcttggc
    40741 gaaatccact tttattagct gatggatgat ctggctgata aatcccttca tatactgctc
    40801 gtcccatatg ttcaataaat gaactgtaca accgcggatc aactttgcct acacgcttga
    40861 cactactaat caacattgtg gcttccataa ctgacctcct ttaatttata catgaataat
    40921 acacctcgtt gaaagcgttg tcaataatat aaatgttaaa cttacttatt ttttatcgat
    40981 tttaattaac caaaatatta ataatgatta aaacaaataa tttaatataa cttttattaa
    41041 caaatat
//
LOCUS       DAXLPC010000015        40425 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.015, whole genome shotgun sequence.
ACCESSION   DAXLPC010000015 DAXLPC010000000
VERSION     DAXLPC010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.015"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            212..604
                     /locus_tag="ACF3UE_000755"
     CDS             212..604
                     /locus_tag="ACF3UE_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3634211.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="ACF3UE_000756"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="ACF3UE_000756"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFD3634212.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2698..2943
                     /locus_tag="ACF3UE_000757"
     CDS             2698..2943
                     /locus_tag="ACF3UE_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634213.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3164..4774
                     /locus_tag="ACF3UE_000758"
     CDS             3164..4774
                     /locus_tag="ACF3UE_000758"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFD3634214.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4751..4963)
                     /locus_tag="ACF3UE_000759"
     CDS             complement(4751..4963)
                     /locus_tag="ACF3UE_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634215.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5066..5935
                     /locus_tag="ACF3UE_000760"
     CDS             5066..5935
                     /locus_tag="ACF3UE_000760"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFD3634216.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6100..7371
                     /locus_tag="ACF3UE_000761"
     CDS             6100..7371
                     /locus_tag="ACF3UE_000761"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFD3634217.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7368..8663
                     /gene="rho"
                     /locus_tag="ACF3UE_000762"
     CDS             7368..8663
                     /gene="rho"
                     /locus_tag="ACF3UE_000762"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFD3634218.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8762..9025
                     /locus_tag="ACF3UE_000763"
     CDS             8762..9025
                     /locus_tag="ACF3UE_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFD3634219.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9470..9919
                     /locus_tag="ACF3UE_000764"
     CDS             9470..9919
                     /locus_tag="ACF3UE_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3634220.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9976..11394
                     /locus_tag="ACF3UE_000765"
     CDS             9976..11394
                     /locus_tag="ACF3UE_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFD3634221.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11394..12254
                     /locus_tag="ACF3UE_000766"
     CDS             11394..12254
                     /locus_tag="ACF3UE_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFD3634222.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12428..13201
                     /locus_tag="ACF3UE_000767"
     CDS             12428..13201
                     /locus_tag="ACF3UE_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3634223.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13348..13713
                     /locus_tag="ACF3UE_000768"
     CDS             13348..13713
                     /locus_tag="ACF3UE_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFD3634224.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13861..15069)
                     /locus_tag="ACF3UE_000769"
     CDS             complement(13861..15069)
                     /locus_tag="ACF3UE_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3634225.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15088..15366)
                     /locus_tag="ACF3UE_000770"
     CDS             complement(15088..15366)
                     /locus_tag="ACF3UE_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634226.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15559..16215
                     /locus_tag="ACF3UE_000771"
     CDS             15559..16215
                     /locus_tag="ACF3UE_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFD3634227.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16657..17454)
                     /locus_tag="ACF3UE_000772"
     CDS             complement(16657..17454)
                     /locus_tag="ACF3UE_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFD3634228.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17451..18635)
                     /locus_tag="ACF3UE_000773"
     CDS             complement(17451..18635)
                     /locus_tag="ACF3UE_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFD3634229.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18660..19907)
                     /locus_tag="ACF3UE_000774"
     CDS             complement(18660..19907)
                     /locus_tag="ACF3UE_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFD3634230.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20122..21867
                     /gene="dnaX"
                     /locus_tag="ACF3UE_000775"
     CDS             20122..21867
                     /gene="dnaX"
                     /locus_tag="ACF3UE_000775"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFD3634231.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21887..22201
                     /locus_tag="ACF3UE_000776"
     CDS             21887..22201
                     /locus_tag="ACF3UE_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFD3634232.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22226..22822
                     /gene="recR"
                     /locus_tag="ACF3UE_000777"
     CDS             22226..22822
                     /gene="recR"
                     /locus_tag="ACF3UE_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFD3634233.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22886..23530
                     /gene="tmk"
                     /locus_tag="ACF3UE_000778"
     CDS             22886..23530
                     /gene="tmk"
                     /locus_tag="ACF3UE_000778"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFD3634234.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23545..23874
                     /locus_tag="ACF3UE_000779"
     CDS             23545..23874
                     /locus_tag="ACF3UE_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFD3634235.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23888..24826
                     /gene="holB"
                     /locus_tag="ACF3UE_000780"
     CDS             23888..24826
                     /gene="holB"
                     /locus_tag="ACF3UE_000780"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFD3634236.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24862..25686
                     /locus_tag="ACF3UE_000781"
     CDS             24862..25686
                     /locus_tag="ACF3UE_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFD3634237.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25679..26026
                     /locus_tag="ACF3UE_000782"
     CDS             25679..26026
                     /locus_tag="ACF3UE_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFD3634238.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26095..26967
                     /gene="rsmI"
                     /locus_tag="ACF3UE_000783"
     CDS             26095..26967
                     /gene="rsmI"
                     /locus_tag="ACF3UE_000783"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFD3634239.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27076..28197
                     /gene="dinB"
                     /locus_tag="ACF3UE_000784"
     CDS             27076..28197
                     /gene="dinB"
                     /locus_tag="ACF3UE_000784"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFD3634240.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="ACF3UE_000785"
     CDS             complement(28251..28853)
                     /gene="nrdG"
                     /locus_tag="ACF3UE_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFD3634241.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="ACF3UE_000786"
     CDS             complement(29168..31357)
                     /gene="nrdD"
                     /locus_tag="ACF3UE_000786"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFD3634242.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31683..32450
                     /locus_tag="ACF3UE_000787"
     CDS             31683..32450
                     /locus_tag="ACF3UE_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634243.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32440..34482
                     /locus_tag="ACF3UE_000788"
     CDS             32440..34482
                     /locus_tag="ACF3UE_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3634244.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34763..34912
                     /locus_tag="ACF3UE_000789"
     CDS             34763..34912
                     /locus_tag="ACF3UE_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFD3634245.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34923..36437
                     /gene="dltA"
                     /locus_tag="ACF3UE_000790"
     CDS             34923..36437
                     /gene="dltA"
                     /locus_tag="ACF3UE_000790"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFD3634246.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36434..37639
                     /gene="dltB"
                     /locus_tag="ACF3UE_000791"
     CDS             36434..37639
                     /gene="dltB"
                     /locus_tag="ACF3UE_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFD3634247.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37684..37917
                     /gene="dltC"
                     /locus_tag="ACF3UE_000792"
     CDS             37684..37917
                     /gene="dltC"
                     /locus_tag="ACF3UE_000792"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFD3634248.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37920..39188
                     /gene="dltD"
                     /locus_tag="ACF3UE_000793"
     CDS             37920..39188
                     /gene="dltD"
                     /locus_tag="ACF3UE_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFD3634249.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39329..40411
                     /locus_tag="ACF3UE_000794"
     CDS             39329..40411
                     /locus_tag="ACF3UE_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFD3634250.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
BASE COUNT        13016 a         7089 c         8463 g        11857 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga atttcggctc cctattctta ttgaagaata gggagctttg tttattgtct
     3121 gagacttttc ctgcacataa attaaaaagg agtttttgaa cttatgacaa aatatatttt
     3181 tgtgaccggc ggtgtcgttt catcaatcgg aaaagggatt gttgcagctt ctttaggacg
     3241 cttattgaaa aaccgcggct taaaagtaac tatccaaaaa tttgatccat acatcaacgt
     3301 ggatccgggg acgatgagcc catatcagca cggagaagta ttcgtaacag atgatggtgc
     3361 tgaaacagat ttggatctgg gccactacga acgttttatt gacatcaatt tgaacaaata
     3421 ctccaacgtg acgacaggaa aaatctattc tgaagttttg cgtaaagaac gtaagggcga
     3481 atacttggga gcaactgttc aagttattcc tcatattaca aatgagatca aagaaaaaat
     3541 catgcgagca gctaaaatga ctgattcaga tgtgatcatt acagaagtag ggggaacagt
     3601 aggggatata gaatctttgc cattccttga agcacttcgt caaatgaaag cagatgtcgg
     3661 tacagataat gttatgtata tccatacaac attgattcct tacttgaaag ctgctggaga
     3721 aatgaaaact aaaccaacgc agcacagtgt aaaagagcta cgtggtttag gtatccaacc
     3781 gaatattttg gtggtacgta cagagcaacc tgtttctcaa agcgtgaaaa acaaattggc
     3841 acaattttgt gatgtcgaac cagaagcagt tatcgagtcg ccagatgtag atacacttta
     3901 ctccatccca ttagttttac aagcacaagg aatggatcaa attgtttgcg accatttaaa
     3961 actagataca ccagaagcag acatgacaga atggaaagaa ttagaagaac gtgtcttgaa
     4021 cttgaagaaa aaagtacgga ttgcgcttgt cggtaaatat gtcgagttac cagatgcata
     4081 tatctcagta gttgaagcat tgaaacattc tggtttcgcc tataattcag acatcgagat
     4141 cgattggatc aaagcacaag aattaacgag agaaaatgta gaagaacgtt tgaaagacgc
     4201 agatggaatc ttggttcctg gtggatttgg tgatcgcgga gtagaaggga aaatcgaagc
     4261 gattcgttat gctcgcgaaa atgacgttcc gtttttaggt atttgtcttg gtatgcagat
     4321 ggcttgtgtc gaatttgcac gtaacgtcgt tggattagaa gatgcgtcat cagctgaaac
     4381 gaatccagat acagcaaaca atattattga tttaatggct gatcaggaaa acatcgagaa
     4441 tttgggtgga actttacgcc ttggattata cccatgtaaa atcaaaaaag gaacgaagac
     4501 ggctgaagca tatgatggag ccgatgttgt gcaagaacgt caccgtcacc gctatgagtt
     4561 caataacaaa tatcgtcaat tgtttgaaga acaagggcta gtcttttcag gtgtctcacc
     4621 agataaccgt ttagtagaaa tcgtagagct gccagagaaa aaattctttg tgggatgcca
     4681 attccaccca gaattgattt ctcgtccaaa tcgcccgcaa aaattaatca aagcatttgt
     4741 cggagcatca ttagcagatc acgaaacaaa ataatttttg aacttgatag aaagagaaaa
     4801 gtagcaagag aaggggataa gcaattttct tgtcactttt ctctttttct gatttgttat
     4861 tatttgtagg aaaaaagata gaaagcaaaa gacttttttc gattaaagcg ctattggata
     4921 ttttattttt tgcaaaaaac ttcttgaaaa ttttcatttt cattgatttt agtagaaaac
     4981 taccgaaatg tttggtaaaa tagggtcgtt ggttaagaat tgtcttaaca aatttagttt
     5041 tacaaaactt aggaggaatt ttattatgcc agtagtatca ggagctgaat ttttaaaagc
     5101 tgctcgtaaa ggcggttacg ctgtcggcgg attcaacaca aacaacttgg aatggactca
     5161 agcaatcctt gaagcggctg aagcaaaaca agcaccagta cttatccaaa catcaatggg
     5221 tgcagctaaa tacatgggtg gttacaaaat ctgtaaagat ttaatcactg atttagttga
     5281 agcaatgaac atcactgttc cagttgctat ccacttagac catggtgatt acgaagctgc
     5341 tttggaatgt atcgaattag gctatacttc agtaatgttc gatggttcac atctaccatt
     5401 tgaagaaaac ttgaaattag ctaaagacgt tgttgaaaaa gcacatgcaa aaggtatctc
     5461 agttgaatgt gaagttggtt caatcggcgg agaagaagac ggaatcatcg gtaacggcga
     5521 attagctgat attgaagaat gcaaacaaat ggttgctaca ggtatcgact acttagcttg
     5581 cggtatcggt aacatccatg gtcaatatcc agaaaactgg aaaggattag cttttgacca
     5641 cttacaagca attgctgatg ctgtaggtcc agacatgcct ttagtattac atggcggatc
     5701 aggtattcct caagatcaaa tcgaaaaagc tatctcaatg ggtatctcaa aagtaaatgt
     5761 taacactgaa ttccaattat catttgctgc agctactcgt aaatatatcg aagctggtaa
     5821 agataaagaa ggtaaaggat tcgaccctcg taaattatta gctccaggta aagcagcaat
     5881 cgttgaagat gctaaatctc atatcgactg gttcggttca gctaacaaag cgtaagcatc
     5941 cacataacag atacgatata taggaatgga gaacgacttt tgaagtcgct ctccattctt
     6001 ttttacttaa aacggcagac catgctcgtt tctttttttt atctatgata aaatacaagc
     6061 atatccatga aaaaagatta ataaacaagg tggaaacaga tgaaaaaaat cgtaatcaaa
     6121 ggaaaccgac ctttagctgg tgaagtaacg atcagcggtg caaaaaatag tgcagtcgca
     6181 ttgattccag ctgcaatctt agctgattcc ccagtgatct tggaaggtgt gccggacata
     6241 caagatgttc attcattaat tgaaatttta gagatcatgg gcgcaactgt ccatttttcc
     6301 aacaacatac tagaaatcga tcctcgagaa gtcgtatcga ttccgatgcc gcacggaaaa
     6361 atcaatagtt tgcgtgcttc ttattatttt atgggaacac tgcttggtaa atttggcgaa
     6421 gcggtagtag gcctgccagg tggctgttat ttaggcccta gaccgattga cctacacgtc
     6481 aaaggatttg aagctctagg tgctgaagtg acaaatgaac atggtgccat gtatttacgg
     6541 acagaaaata aaggattgcg tggcaatcgg attttcatgg acgtggtttc agtcggagca
     6601 acgatcaatg tgatgttagc tgctgtaaaa gcaaaaggac agacagtaat tgaaaacgct
     6661 gcacgagaac cggaaatcat agatgtggca actttactga ataatatggg ggcaaaagtt
     6721 cgaggagcgg gtacagatgt gatccgtatc gaaggagtcg aaacattaca tggctgtcgg
     6781 catttcatga ttcctgaccg catcgaagca ggaacctatc tagcattagc agctgcagta
     6841 ggaaatggta tcaaagtgaa aaatgtgatc tttgaacatt tggaaagctt tatagcaaaa
     6901 ttgcaggaaa ttggtgtcca tatgaaaatc agcgaagatg aaatcgaagt ttacccctcg
     6961 aaagaattaa aacccgcaaa catcatgacc tatccttatc caggatttgc cacagatctg
     7021 cagcagccac ttactgcgtt actattgatg actacaggca cttcagaaat catcgatacg
     7081 atctatgcga aacgtgtgaa ccatgtgccg gaactagcac gaatgggcgc tgatattacc
     7141 gtggaaggaa atatgatcat cgtgaatggt ccaaataaac ttcacggcac agaagtcgtg
     7201 gcttctgatc ttcgggcagg tgcttgttta gtgattgctg gactattggc agaagggaca
     7261 acgacgattt acaatgtaga ttatatctta cgcggttatg atcatattat cgagaaacta
     7321 acagccttag gggcatcaat tgaaatgata gaggaagtgg gagctgaatg agcgattatt
     7381 tgacaatggc agaactagag aacaaaacgt taaaagaagt ttatagttat gccaaagaat
     7441 ttaaaattcc ttattacagt aagatgaata aaaaggaatt atctctagct gtgattcgtg
     7501 cacaagcaga gaaacaagga ttttattata tggaaggaat attggatatc gttggtcaag
     7561 atggttacgg ttttttacgg ccaatcaatt atggaccaag tgcagaagat atctatattt
     7621 ctgcctcaca aatcagacga ttcagtttga gaaatgggga caaagtggca ggaaaagccc
     7681 gtccacctaa agaatcggaa cgttattatg gtttgatgca cgtggaaagc gttaatggaa
     7741 aagatccgga agaagcaaaa gaacgtccgc attttccagc cttaacacct ctttatccgc
     7801 aaagacagct tcaactggaa acaacaccgc aaagactatc tacccgaatg atcgatatct
     7861 tttctccaat cggttttggt cagcgtggat tgatcgtcgc accgccaaaa gcagggaaaa
     7921 cttctgtatt aaaagaaatc gcaaatggta tcaccgaaaa ctatccggaa gtagaattaa
     7981 tcgttctact gattgatgaa cgaccggaag aagtaacgga tctagaacga agcgtgaaag
     8041 gcgacgtggt atcttctaca tttgatctgc agccgcaaaa ccatactcga gtttctgaat
     8101 tagtattgga acgcgcaatg cgtttagtcg aagataaacg agatgtcgtt atcttgatgg
     8161 atagtattac tagacttgct cgggcctata acttagtcgt tccaccaagc ggacgtacat
     8221 tgagtggcgg gattgaccca gccgcattgt ataaacctaa gaaatttttc ggggcagcaa
     8281 gaaacatcga agaaggtggc agtttgacga ttttagcgac cgctttagtc gatacaggaa
     8341 gccgtatgga tgacgtgatc tatgaagaat tcaaaggaac tggaaatcta gaattacaac
     8401 tttcacgtga attatctgaa cgtcggatct tcccagccat cgatatcaaa aaatcaggta
     8461 cccgaaaaga agaattattg atgccaagtg aagaattaga agaaatttgg aaacttcgaa
     8521 aaaatatgac tggagattca ttagaatata cggaacaact gatccgcttt ttgcgtaaaa
     8581 caaaaaacaa tcagcaattt ttcaaagaat ttcaagatgt ctcctttggt aaaaaaaatc
     8641 cgaccagaaa tctgaaaaga taattgcaac cttgactgaa acatgttaag atgttaatgt
     8701 tgtaaatcga caaatcaact ctggttcagc aaatggagca gggcaaagga gcgaaaaaat
     8761 catgaaagaa aacatccatc cagattacca cccagtagta ttcatggatt caacaactgg
     8821 tttcaaattc ttgtcaggtt caacaaaaac ttcacaagaa acagttgaat gggaagacgg
     8881 taatacatac ccagtcatcc gtgtcgaagt aacttctgac tcacatccat tctacactgg
     8941 acgtcaaaaa ttcacacaag cagacggacg tgtggaccgt ttcaacaaaa aatacggtct
     9001 caaagacgca aacgctgcgg aataataaaa acgctgataa ctcaacgttt agcagactat
     9061 ctgataggga tagtctgttt ttttatgttt tttgccaatt taaaacttcg tttgatgctg
     9121 aaaaagtcgt aggatcataa tgcacaaaac aatgaaaaac tagtatatag ttttaattat
     9181 ccacttgata aaaacacctt atattaacga aatgaagagg ggttatttcg aagtaaaaaa
     9241 ccatttacct aaaattagaa gctaagcttt cctttcaagg aaggcttttt gttttgttat
     9301 agacttgcga ttgtttgtga gctagatcgt tcattttaat gacttataca cgcggatgat
     9361 gggtcttttt cctctgttca ttcataatat tgaacggtac agctagcgat gctatactga
     9421 cctcagttcc aagaaaacgt taacattttt tgtgggggag aggtttttta tgaggtttga
     9481 tcaattgatc gcagaagaac tgattgtttt cgatccatcg atagattcaa aaggatcatt
     9541 atttgagcga ataggggatg tgttgaaaaa aacaaataag gtaagaaatg ttcaaaaagt
     9601 cgttaaggca ctattcaaac gagaggagga gatctccaca ggaatagaag atggatttgg
     9661 gattccccat gcaaaaagca aatatgtgac aaaaccagca ctgtgttttt ttcatacagc
     9721 caaattaacg gactatagcg ggatagatga aatgccaatt gaatatattt ttgccatcgt
     9781 agttcctgaa aaatcagcag atatgcatct agagattctc agcacactct ccagacgatt
     9841 gatgaatgca gattttagaa agggaataaa agaagccact acgccagcag atatcatcag
     9901 acagattagt caagaatgaa aatagtagag tctttgtccg agtatcgata gtgaagaaaa
     9961 aggaggaaaa taatcatgaa aatcgttggt gtaactgctt gcccgactgg aattgctcat
    10021 acttatatgt cggcagaaaa attagaagta acagcaagaa atctaaacca tcaagcaaaa
    10081 ttcgaaacac aaggtgtaaa aacagaaaat cagttatctg aacaagaaat caaagaggca
    10141 gatgcaatca ttcttgcagt agataaagaa atcgaattgg accgatttgc cgggaaaaaa
    10201 gtaaagcgtg tctctacaag ccgagcaatc aaagaaccgc aagtagtaat agacgaagca
    10261 ttgagagata ttggcgtatt cgttgtgtct aatgaaaaag aaccagctgc aaatgagaaa
    10321 aagccgacaa tctataatca tttcatgaat ggtgtgaatt acatgcttcc atttgtgatc
    10381 gcaggcggaa tcatcatcgc actgagtttt gcctttggga ttacagcggc tgatcccaac
    10441 tcagcagact ataatgtgtt agcagctgca ttttcaagga tcggaggaga tacagcgttt
    10501 gccatgatgg ttcctgcgtt aggcgcgggg attgctacat cgattgctgg aaaagcaggt
    10561 tttgccccag gaattgttgc cggattactg gcctctacag gtggttcagg ttttcttggc
    10621 ggaatgattg gtggcgtgct agcagggtat atctgtgatt ttctggcaaa taaaattagc
    10681 gtaaaaaaag aattttctgc tatttatcag ctgattgtcg tccccttttt atcgatctta
    10741 attattgggc ttttgatggt atttgtgatt gaacaaccga tcacatgggt gttggatgct
    10801 ttgacaaatt ggctgaatag cttgggaaat acatccgggc tattgttcgg attacttatc
    10861 gggatcatga tggcagctga tatgggtggg ccgatcaata aatcgacttc gactttctcg
    10921 atcggtttga tgtcagctgg agtaaatgca ccgattgctg cttgtatggc tgcaggaatg
    10981 acacctcccc taggtattgc tttagccact ttattattca aacataaatt taccaaagaa
    11041 gaacggactt caggtcaatc atgctggatt ttaggcgctt cgtatattac agaaggtgct
    11101 ataccgtttg cggtatctga cccgatccgc gtgataccta gtttgatgac aggttcagca
    11161 gtcgctgcag ggatttccat ggcagtagga gttacttcaa tggcacctca tggagggatt
    11221 tgggtgatgc taattccaaa tgttatgaac aatttaccta tgtatgtctt ggcaattgca
    11281 tcaggtacag tcactacagc ctttatgctt ggactattga aaaaaacagt gaaagagaaa
    11341 aaacaagaca agtggacgaa aaatgaaaat ctaacaaatg aggtggaagc gtaatgttat
    11401 atacaatgaa agagttattg aaagtggcta aagagaatca atttgcagta ccagccttca
    11461 atatttgcag ctatgatatg atgaaagcaa tcatcgaaga agcagagaga ttagaagcac
    11521 cagtaatctt agaaattcat cctgatgaaa tcgcctattt aagtgatgag tttgttgcgg
    11581 cagtaagagc ctatgcttat acaagtaaac tgccgatcgt tatccacttg gatcatggcg
    11641 gtacgataga agatgtctta cgggcgattc gaaacggcta ttcttccgtg atgatcgatg
    11701 cgtctttgaa atcattcgac gacaatgtac agattacgaa aaaagtggtt gcgttagctc
    11761 atgcggtaaa tgtctcagtg gaggctgagc ttggaacgat tgggaataat ggttctgctg
    11821 aaggaggtgc tgaaacaatc atttatacag atcctgatca agcgaagatt tttgtgaaag
    11881 aaacaggaat cgatacactt gctgtagcaa ttggaacagc gcatggcttg tatccgaaaa
    11941 acagaactcc aaaattaaat atcgacttac tgaaagaatt gaaccaacaa atcgatcttc
    12001 catttgtttt acatggcggt tcaggtaatc cggacgcaga agtcagcgaa gcagtaaaat
    12061 acggagttgc caaagtgaat ttgagctcag atcttaaaag cgtctttttc aatgctttga
    12121 gagaaatatt gagtgaaaat ccatcgatgt acgagccgaa tgcaatttat ccagcagcta
    12181 ataaaaaggt acaagaagtg gtcaaacata aaatggaaat tttgaacaca gtaggcaagg
    12241 ctagtttata ctaaaaataa aaatgtgtgg tcaagagggt atgacaatag tcttgtcata
    12301 ccctcttaac cacacacgat gttcagaagt agttttttcg aaaaatttct tcttatttct
    12361 cgaagccaat cacttctgtc acaacctctt ttttcctgtt actatataaa gtaaatgggg
    12421 tgattttatg ttgaatgaag tggagaatag acagcaggag attgtgaatt atctaaaaaa
    12481 caaccaattt gcaagagtca ccgatttgat cgagttagta aattatagcg aagccacgat
    12541 taaacgtgac cttgtttttc tggaaaaaag tggattgatc cgtagagttc gcggtggcgc
    12601 catgcttatt gacaatcgaa aaattgacgt gccttacctg atgaagatca ccaaattaga
    12661 agaagaaaca gaaaaacgta agattgcaga tacagcttct tctttgattc gagatgatat
    12721 ggtcttattc ttggattcca gtacaacctc tttacactta gtcagaaacc tagcaagatt
    12781 tgatggtttg cagatcatta cgaatggcat cgtcacagct gctatgttga gtgaatatac
    12841 aacggcaaaa gtatctgtat tgggaggggc aattgttccg aaacgagcaa caatcaacgg
    12901 ttcaaaagcc tataacgatg cattgtcata ttatgcggat ttagcgataa tgagttgtcg
    12961 cgggctagat ttcagccaag gagtaacaga aactcatgaa ggagaggcaa tggtcaaaaa
    13021 agcttttaga aaacaatcag accggcttgc cgttttagtt acacagcaaa aaattgcaca
    13081 taaattcatg catcaagcca ttgcttttca tgaaatcgat tatctggtga caagtaaaga
    13141 actgacaaaa gaacagtatg cgaaagtaaa ggaacaccat atcgaatgtc tgtacggata
    13201 aattattacg tgaatgttct aagtggcttc ctcattttta gataggacct tatctttgct
    13261 cgcttctctc agccgatggt ataataatga aaaggttatc ttgttagata atcttacttt
    13321 tttatccagg agaaaggagt gcagaaaatg aaacatgtga aggcgttggt agtgaaggca
    13381 atcatgatct gggcgattct gtgggtcgtg ctgacaggtt tatacggtgt tagctttatg
    13441 gattcaacga ttgttggggt aattattgta gtcatgatct atgtgctagg ggatctgttg
    13501 atcttacgta aagtagggaa catcgcagcg acgatcgcag atgctggttc agctgcagtt
    13561 atcttgtggc tctatctata ttttatgaat gatacagtcg atatttggat gaaagtattg
    13621 attcctgctc tattgatcgg tgtggcagaa tggttcttcc acaagtggtt gctaagtcaa
    13681 ggcatcgtac cagatgaacg gaaaatggaa taaatcaaca gttaaactat tcttatcgat
    13741 aaatgaaagc tttaaaaata aatagatgtt taattaagaa taatcataaa ctatttttac
    13801 tcaaaaaacc gctcagatta ttttcagatc tgaacggttt tttttatcta ttcatcaaga
    13861 tcaaatttca tttttcaatg attcaatcaa ttcgccctct gcttcatgac tatgttttcg
    13921 gccattaaca agatagagtg ctgtacatat caatggaatg actccggcaa tcacatacaa
    13981 tcctctaaat gaagtaagag attttagcat ccccatcaaa taaggaccaa cgcctaagcc
    14041 taggtctaaa ccaataaagt aggtagataa agcaatactg attcgatgtt cgcggacgat
    14101 ttttaaacaa acagcctgtc catttgacat aaacgtacca taacctaggc cgactaatgc
    14161 tccagagata agcaatgtca cactattcgt cgttacactc agtaaaaata atcctgctgt
    14221 taagaataaa tagctaggat acatcacgta ttgttctcct ttgacatcga aaatccttcc
    14281 agtcaatgga cgtgtaaatg tgatgaccaa agcatatacg acgaagaaaa atgacccagc
    14341 agcaactaag tggattactt ttgtataaga agataaaaat gataaaacac ttgaataaga
    14401 aagacccatc aaaaaggcaa ttcctgtaat gaaaagtgct ttcttttcaa taaaactatt
    14461 gatattccat gagcgaagag atattttttg ttcttcagat aatggaatat tttttacagg
    14521 aaagacaagg caggcaatcg taacaaagaa gaccagtaca attgaaaacc agataatgaa
    14581 acgaaaatca gtcatattca gcaaaatcat tcctaaaaat ggcccaacag cggcagctaa
    14641 actagtactt aatccataat aattgatgcc ttcccctttt ttagatgcag ggatatatgc
    14701 agtaacgata gcatttgtag ctgtagaaac tgtaccgtag ccgaatccat tcaagaatcg
    14761 aactaaatac aatgccccga tagttggcgt ataaagatat gctaatgttg aaaggagata
    14821 gaagatcgcg ccgcctctta aggtaaactt ccgaccaaat agttctaact gtttccccat
    14881 gaataagcgt gccagcaatg ttccgatgat atagatccca gaagcaaaac ctgcttggct
    14941 caagctggcg tgtaaggtgt cttgcgcaat gactgccatg atgaccatca acagataata
    15001 aatcaggtag acaataaaat tgatcaatgt gattccaata aaatatttat taaataattt
    15061 cttttccatg tatgttatac attcccctta agctgaatat gcttttaatt tttgtatttg
    15121 aacttctaca tcgtgataat tggatggata gcgatcaaca agttggcgaa taaataaatc
    15181 tcttgtagac ataaacagat ttaaaaattc ttcgcattcg tttgttggat tctcatccac
    15241 tgctttgatc aattcgatcg agttttgata cgcatcattt aaaaagacta aagaagcttt
    15301 catatcaaat cttgtttgat atgctgtttc taatcgatta atgattgtgt tcatccagta
    15361 attcatgttt tttccctcta ttcttaaaaa attttacttc tgcagtataa cgaataaaaa
    15421 aaaggaaaaa aatcgcataa gtgatggaaa aaggtactta acaaatgtta atatcattag
    15481 taaaatacct ttggacttta aaaagtttta aagtactgta tgatcttttt agatgaaagt
    15541 ttggatgggg gagcatcatt ggatagtaga gtcttaaagg aatatttgga taaaaatgat
    15601 tttccgatta tacgcaaagg atatcataaa tatttgacat tcgaagggat ggaagattcc
    15661 catacgtata tcttgaaaga gggaacggta aaagcaagtg ttatttcaaa tgatgggaga
    15721 gaatttaacc ttcgctatat caaagatctt gaaatcgtct ctcttttaaa agacgaatat
    15781 tcacaattca tcgattcgcc gtataatatt cgagttgaat cagaatatgc agagttttat
    15841 cgaatcaatc gtgtgcgctt ttggcaaaat atcaaccaag acccaaagct acaacactat
    15901 gtaaaagagt attaccgcta tcgtctgctt tattcgatga aaaaaatgca gcaaatgcta
    15961 ttaaacggaa agctgggagc tgtttgtacg caactttacg aattatatga tttattcggt
    16021 gtgcggacag aagaagggat gctgatcgat ttttcgatca cgaatgaaga aatcgccaaa
    16081 ttttgtggca tctcaactgc tagcagtgta aacagaattt taaaacaact gaaaaaagat
    16141 ggtattatca ccgttaaaga ccatcatatc gttattttga atatggactt gttagaagac
    16201 aatattatct tttgatgaac aaagaggttg tgaaatcagc gttttgacct gagtattaga
    16261 gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
    16321 agctgattga acaccgttta ccaagaggtt gtgagcctgc cgtttaactc tgagtcacaa
    16381 ggaacaattt caaaaaacag cttttcatgt ttgatgaata ttgtgacttg tgaccgagga
    16441 gttggtagga gaacaccgtt taccaagagg ttgtgaaaaa gctgttctgc atcaagtaat
    16501 aagaagagcc aagtaaaaac agtctcttat gtttttaact tggctggact tatcaccgta
    16561 gatgtaagct tttgaacgcc gtttatttgc aacaaaaggg gctgtgacac gatttttgtc
    16621 acagcccttt ttttgcgaac attcatttag caatttttag aaacttctgc cgccaccgcc
    16681 aaaagtcccg ccaccgctag aatgggtagt acttccgcca ccgccgcttc caggaggtgg
    16741 gcttttgggg attcttcttg tcgtgacaaa agaatttgtc agacgatcgg ttttttcagt
    16801 taatttgata ctggattttt ctcggaatgg atatttgtag atgcctgatt tcaattgata
    16861 acgcgaaaca gtcacaaaat aaaagacaag actaaggata agagccaaaa caacagcaat
    16921 gatgatttct actgtcgtca aaaccttata gcgtgtaatt ttgccagttt cttcgtctac
    16981 acgataatgt cctcctggaa ctccgtcttc cacatatgtt gctgatttag acaggtaagc
    17041 ttttgcagca ttgtaatagg cagcatttgt catctgatca taaacatcat ctaagatcga
    17101 atcgattctg ctatcagtca aataatcgat catattacca gaagtcgaaa tgtagatttc
    17161 acgctgtccc atatctaata gcaatactga gccattttga tcatttccga ctgcgtctct
    17221 taagtaatta tcagcaaagt ctcttggttc ttctgaatta gatgtagtcg ttacgatcaa
    17281 gactcgtcct ttgatttttt cattcagctt ttctgcctgt tgttccaaag attggatttg
    17341 atctgttgtg aataacccag cctcatcatt taccgtagct gtatctgcat gagtagccac
    17401 cggccagcca acacttacta gcaaaagaaa gaataaaaaa aattttttca tcatatcaag
    17461 taacctccga tcagaaagag gatcgctagc ccagcgaaaa tcccaagagc ggtcagtccc
    17521 aattttttct ggctgatcgg caggacaccg ctgacctttc ctgtttgtcc attcattgcg
    17581 tagtagtaga cttttttact tgagtcattg cttcgataag taacaagcca taccggcagt
    17641 aatacgtaat tatttacttc gtttgtgatt gaagcagaag ttcgcacacc ggtcaatgtt
    17701 gtatatccat ttgcggtatc ttttaacagc ttctctgaat agtcttttaa ttcagattga
    17761 atctgtgatt tgattgcctc atattcgata tctctttttt ctgcttggaa cccggctaaa
    17821 tactggcttt taaaatcaat tgctttatct aacgggaaag gttgcacgcc ttcgaccatc
    17881 ttttgttgcg tattttttga taaggcattt tttactagtt ctttaaaaga aagcttgcct
    17941 gctcttgaaa cagcaaattg cttcgtttct gtgtattcga tgtcacctat ccgccatatg
    18001 cggataactg taccattcgc ctgcatggca ccatctactt cagcatctgt agcccaataa
    18061 gggaaataca cacctgtcaa cttatcgatt tgatccttat tgaaaaaagc tttgggaaca
    18121 aaccattttt tcttggtcca agcgagaaat ctgttgattg cttcttcttt ctcgacagca
    18181 aaaggaagta ctttatttgg caagaattct ccgcttaaac gtcccgatag tacgacggga
    18241 ttatggcagt agtaacaata agtcgcagca gttgtcgcat cagtcacgat ctctgcacca
    18301 cagttgggac aaagaaaaag atctatcgct gcggtattat ctgcagattc gtccgctgta
    18361 tctgaaaaac cgcctgcctc gtcaaccgct ttgcgctcgg cttcattcat atcggcaagc
    18421 tgttcttggg ctgtaaaagt aaaatcttcg gtaggtgaag gttcttcttt gctttcttcg
    18481 ccagccatac gcgcttcttt ttgcttttgc tcatattggc tgacttcttc ttctgtatag
    18541 atattcaggc agtattcgca atgaaatttt tggtctttgg gatcaaaagt caacggaccg
    18601 ccgcaattag gacatttatg tgtaagaaca tccatcagct gcacaccttt ctaaataaat
    18661 taattaacgg ggattccttt aaacggttta ccacagtttg gacagaattt agggatgccg
    18721 ttggaaagat ccacgatctc attgcattca ctgcatcgca tttgtagctt aggctgaacg
    18781 ttttctacag gtttggcagc tccgcagttg gaacagaatt ttccggaatt ttctgtcccg
    18841 caaactggac atgtccaagt atccgcattt ccttgtgcag tttgttgatt ttgtttttct
    18901 gcttgttgtt tgatttgttc ttggttattt tgagctgctt gagaaagata agaaccattt
    18961 gcattcattc ccatacctac acccataaag ccggtcattg ctcctgcttc attttttccg
    19021 gctgcttcca taccacgtgc aatggaacct tgcacgtatc cttcacgtac gctaggatca
    19081 cctagcatcg ccccttcgtt acgcatattg atcagtttca cagaatcatc ggtgtaagaa
    19141 atgctggcta cagccacaga aacaatctcc atcccacgta attcacgcca agaatcatcc
    19201 aatgcagtat ccatgtattt gcttaattcc aaactcttag atggtacata agaaatccgt
    19261 tgaccatctg cagacatctg attgattgct gattgtagcg ctgttaggaa ttcagctaaa
    19321 tactgctcat tgatatcatt gatttccact tgtgttttgt ttttagggat tgcgtttgta
    19381 taaaataaaa tcgggtcaac gacatgaata gaataagtgc catgtgcccg taagaataat
    19441 tctgcgttat agaaattgtc aaagtagttc aacggcgcgc ttgtaccgaa tttgattccc
    19501 tttatttctt ggagattgat ataaaaaact tgttgtttct gcggtgtgac gccgccaaat
    19561 ttgaatcggt caaaagtttc agcaattgct tctttcagtg ttccattgaa catggaagga
    19621 gctgcgtcat ttttaatggt gtaataacct tcctcagcgg tataatcgat gatttttcca
    19681 ccatcgacca aaagcatcat catgtttgga tagacatgga cgactgttcc gtctgttaaa
    19741 acatcttctg ttcctttacg attggagcca cgtttgtcat ctttgcggac tttgacacct
    19801 tttgtcatga ccgttgtatc actcatattg tctggttcga tgacttctag ccattgatct
    19861 gccagaccgc cgccaaccat acttgttgct gctttgataa gacccataaa aaattcctcc
    19921 tctgattcag ctagtgccaa acaattattg tttatttatt ataccatagg aagatgtgaa
    19981 acttctcgga ctagagacgg aattgaaatg gaaaattgcg tattgtttaa atacctgaaa
    20041 aagccgagaa ggatagtagt ttttttacct aatatcacgt ataataagag atagtgaatt
    20101 ttttaaaaaa gggggatcct tatggcatat caagcacttt atcgagtctg gcgttcgcag
    20161 cgtttcgaag acatcgttgg acaaaaagct gtgacacaga cactaaaaaa tgctattgtt
    20221 tcccacaaaa cctcacatgc ctacttgttt acaggaccca gaggaaccgg aaagacgagt
    20281 gcagcaaaga ttttcgcaaa agcaatcaac tgtccgaaca gtaaagacgg tgagccatgc
    20341 aacgaatgcg aaatgtgtcg atcaattact gctggtacgc aagaagatgt gatcgaaatc
    20401 gatgctgcca gcaataacgg agtcgaagaa atccgattta tccgtgatcg ggcaaattat
    20461 gcgcctacaa aggcagcgta caaagtgtac attattgatg aggtacatat gctttcaaca
    20521 ggagctttca atgccttgtt gaaaacattg gaagagccaa aagaaagtgt catattcatc
    20581 ttagcaacga ccgaacctca caaaatacca gctacgatca tttcacggac tcagcgattt
    20641 gattttaaac ggatcaatac ggcagatatt gtcgaacatc ttgaatttat cttgaaagaa
    20701 tcgactatca gctatgaacc agctgcattg aatgtgattg cccgttctgc agaaggcggg
    20761 atgcgggatg cattgagtat tcttgatcag gcaatctcgt ttagtgaagg aacaattact
    20821 ttagatgatg ccatgcaagt gacaggtagc ttaactgacg aaatgatgga cagttacttg
    20881 agtgcttgcg tgaaaaaaga agtaccagaa gcattggaaa cattgaacca aattctcgca
    20941 gccggcaaag aatcacgtcg ctttctagag gatatgttac aatactgccg tgacttgctg
    21001 atgtatcagc aagcacctaa cctagttgag gaacaatcga gtacgatcag aagtacattt
    21061 acagaattgg cacaaactgt ttcagcggat cagctgtttt caatgataaa gattttgagc
    21121 gatactcaaa atgaaattcg ttttaccaat agtgccgcta tttatttgga agtcgctaca
    21181 gtcaaacttg cacagctacc gtctgcttct gttccttcag cagatgtagc atttgcagat
    21241 gatcagatag taaaacagct acaacaagag attaaggaac taagaaacga aatcaaggaa
    21301 ctacgcagta atacaggaat tgagaataca aaagtacagc cggtacagca aacaaatcat
    21361 aaaaaacaga caagtaccta tcgtgtaccg acggaacgag tatataaagt tctgcgggaa
    21421 gcgacaagac agcatctgaa ccaagtaaaa gaagtatggg aagacttgct gatgagtcta
    21481 tctgtcactc agcgagcaat gcttaaagca agcgaaccag ttgcagctgg acctacagga
    21541 ctagtgattg cgtttgatta tgagattgtt tgtcaaagag cagcaaatga cgaagaattg
    21601 cagctttcgg tacacaacaa cttaagccga atgatcaaag attatgcgcc tgatcctgtt
    21661 tatattacaa gagaaagctg gccagaactt cgaagaaatt atttgacgca ggcacaagaa
    21721 gagggaacag aaaactcttt tgcttctgaa gactcagaag gagaaatcga gttgcttcct
    21781 caagaacaag aagtaccaga agaaacactt gtagtaaaag cagaggaact gtttggctcc
    21841 gaagctgtta cagtggtaga tgattaataa aaaggagtag ataattatga tgcgtggaat
    21901 gggcaatatg caaggcatga tgaaacaagt acaaaaaatg caaaaagaaa tggcagaagc
    21961 acaagagctg ctaaataaaa cagagtttac aggtaaagcc accaatgaat tggtcaaagc
    22021 ggtttttaca ggcgatcgtc gcatgaaaga tatccaaatc aatgaagaag tcgttgatcc
    22081 tgatgatatc gagatgcttc aggatcttgt cgtaatggca gtcaatgatg cgatcgcaca
    22141 aattgatgtg gaaactgaga aaaaattagg gaaatacgca aaaggtttgc caggatttta
    22201 gttttaaact gaaggagtaa tgaatatgca atatccagaa ccaattgcga aactgatcga
    22261 cagctacatg aaacttccag gaatcggtca gaaaacagcg acaagactcg ccttttatac
    22321 gatcgatatg aaagatgaag tagtaaatga atttgctaaa tctttgttaa gtgtaaaacg
    22381 cgatttgcat ttttgtagta tctgcggaaa catcacagaa gaagatccct gcgaaatatg
    22441 tagaaatcct tcacgtgatc gaagcgttat cctagtggtc gaagagccga aagatgtaat
    22501 ggcaatggaa aaaatgcgag aatatcacgg actttatcat gttctccatg gtgtgttatc
    22561 accgatggaa gggacaggtc cagaagacat caatatttct tctctgttgc agcggctgca
    22621 tgatgcagat gtaaaagaag tgattatcgc aacaaatgca acaacagagg gagaagcaac
    22681 agctatgtat ctctcacgtc tgatcaaacc cgcaggtatc aaagtgactc gtctagcaca
    22741 tggtctgtct gtaggctctg atatcgagta tgcagatgaa gttactttat tgaaagctgt
    22801 cgaaggaaga cgtgagttat aaatttctaa ttaagtgttt tttcagatac aatataaaag
    22861 cagcacaaga gatgggggca acaatgtgaa cggactattt attacaatcg aggggcctga
    22921 tggtgcagga aaaaccagca tcttgaatga actttaccct cttttgaaag aagtagcaaa
    22981 aacagaaatc attcaaacaa gagaaccagg aggcattccg attgctgaag agatccgagc
    23041 agtgatcctt gatccaaaaa atgatcggat ggatgaacgt acggaagcac tgctttatgc
    23101 agcagcaaga agacaacatc tagtcgaaaa ggttctgcct gctctggcaa aagggaaaat
    23161 cgttttatgc gatagatttg tcgacagttc tcttgcttat caaggtgcag gccgacgcat
    23221 cggcgttacc gagattgctc ggttgaatga gtttgctaca gaaggtacta cgccggattt
    23281 taccctttat cttgacgtag attcagacac cggattaaga agaatcaaga aaaacagaca
    23341 aaatcaaatc gaccgtttag attcggaagg tttggaattc caccagcgtg tacgtcatgc
    23401 ttacttaaag ctggcagaag agaatccgga aagaatccac aaagttgatg caagaaaaag
    23461 ctttgaagaa gtgctgcaaa caagttatca tacaattatt gaacagtatc cgcaattttt
    23521 tgaaaactag gaaggtgaac gtttatgaaa attattttag cgattatcca agacaaagac
    23581 agcaaccgtt tatcaaatga attgattgat gcaaatatcc gtgccacaaa actatcatcg
    23641 acaggcggct tccttaaggc tggaaacagt acgtttatcg tgggtattga agatgaccgt
    23701 gtagaagaag cattggaaat catcaaaaaa acgtgtgaat caagaaagca atttgtatct
    23761 acacctgtta cactggatat ttcgatggat gggggcgtcc cttatccagt agaagtagaa
    23821 gtaggcggtg ccacagtctt cgtcttacct gttgaaggat tccatcaatt ttaggaggag
    23881 ctgagctatg aatcaagaaa taaacttggc tcaaatgcaa ccgatcgtgt atcagcagct
    23941 tcaacggagt tttgagcatg ggcgtatcgc tcatgcttat ctttttgaag gggagaaagg
    24001 aacaggaaaa catgaagtag gtatatggct tgcacagcac ctgttctgta cccaaatgaa
    24061 agacaatctg ccttgtggaa aatgcaacaa ttgtcagcgg atcgaaaaga aagaacatcc
    24121 agatgttttg gttattgaac cggaaggaca aaccatcaaa gtcgatcaga tcagacgttt
    24181 gcagacggaa ttcagtcgca gcggttacga atcaagaaaa aaagtttttt tgatcaaaga
    24241 agctgaaaaa atgaatagca gtgcggcaaa cagtttgttg aaattcttgg aagagccccc
    24301 tggagatttt ttagcggtgt tagaaacaga tgcagtagga agaattctcc ctactattca
    24361 atctcgttgt caagttctgc attttcaaga actttcgaaa gaagcactga tccatcgatt
    24421 gcaagaagag cagattccat tggaaaaagc aaaacttttg gctttcttaa caaacagttt
    24481 aggaaaagca gttgaaatct ctcaagatga atggtttaat gatgctaagg acttgattta
    24541 tcaatggttc gtttacttgc aaaagcaaga tactcaagcc tttatctatg tccaaaaaaa
    24601 attggtaaaa tcatttaaag aaaaaacaca acagtttaca ggattatctg tcttgatgtt
    24661 ttattatcag gaagcacagc gtcaagcagt agcaaacggc gaatatggca aagtgaaaca
    24721 gataaaccag ataattgaac ggatattgat cgcagagcag aaactacgca gcaatgtcag
    24781 ttttcaggct gttgcggaac agttcgtttt gcatacgatt ttttagcttg ccgcaaagga
    24841 tgatgatcaa ggaggatgga aatggtagaa gtagtaggtg tccgatatag agatgcaggt
    24901 catatctatt attttgcacc aggagactct gaatatgttt atagtgacaa ggtattagtc
    24961 gaatctcagc aatccttaca tattgctact gttgtccttc ctaaaaaaga gattgatccc
    25021 aatgaccttc ctgaagctat ccgtccgatc ttgcataaag cgtcacaagc tgaattagaa
    25081 aaagacaaaa aaaacaaaaa agatgcttat gatgcattga aaatcgcaaa agaaaaagtg
    25141 cagttgcgtg agttggaaat gaaaatggtc aaagccgaat acacatttga tcgaaataaa
    25201 ttgatttttt ctttcacagc ggacgggcga attgacttta gagaattggt aaaagatctg
    25261 gccgctgtat ttcgtactcg tattgagctt cgacaaattg gtgtccgcga tgaagcaaag
    25321 ataataggcg gaattggtcc atgtgggcgt ccattatgct gttcttcttt tttaggcgat
    25381 ttcgtgcctg tatcaatcaa aatggcaaaa gatcaaagtt tatctttgaa tccaacaaaa
    25441 atttccggtt tatgcggacg cttgatgtgc tgtctgcaat atgagagcga agaatacgag
    25501 acagcgaaaa aagaactccc tgactttgga aaagtaattg ctacacctga tggtaaaggg
    25561 aaagtcgtag ggttgaatct gcttagccgt atcgttagta ttcggctgac tggacgggaa
    25621 aatcctgtcg aatatgaatg ggatgaattg aaagaattta tccaagtagg tgagatgaat
    25681 ggataagaga tcattatacg acggattgaa tcaattagaa tcagagttga gaaatacatt
    25741 aacagaactt gttgaaatga agcatgcttt gcatgagatc gtagaaaaaa atacaacttt
    25801 ggagatggaa aatcaacgtc tgcgggaaca cctgcgggaa ttgaaccaag ttgcacaagc
    25861 tccagctgaa aatgtgaagc aggaactttc taagtctcgt atgaatcttg aaaaaattta
    25921 tgaagaagga ttccatgtct gctacgattt atatggatca agaagggaca atgacgagcc
    25981 ttgtgcgttt tgtctagaag tgatctatcg cgaaagcggt cgatgaccaa taacaagagg
    26041 agactggagc ggagaaatac tgctccagtc tttttattaa ggagattgtg acagatgtat
    26101 aatcaaaaaa gtttcaaggg aaatccggta tatggggatt tatatcttgt accgacgcca
    26161 attggaaatt tagaagatat gagctacaga agtgttcgta tgctgcaaga atccgatctt
    26221 atcgcaagtg aggatacgcg taatacacaa aagttattga atcattttga aatccataca
    26281 ccccaaaaaa gtttacatga acataattat aaagaacgtg tccctcaatt gattgctttg
    26341 ttaaaagaag gaaaaacgat tgctcaagtc agtgacgcag gaatgccttc catcagcgat
    26401 cctggacatg agctagtttt agcctgcata aaagaaggga tttctgtgat ctctatccca
    26461 ggacctacag ctgggatgac ggctttgatt gcttcagggc tagtgcctca accattttta
    26521 ttttatggct tccttccacg taagaaaaaa gaacagaaag aaacattgaa aaagctaaaa
    26581 gaacagacag ttacgctgat tttttatgag tcaccttatc ggatcactgc tacattgacg
    26641 aatttcttag aaatttttgg aaatcgccaa gtcgttttgt gtcgggaatt gacaaaggtc
    26701 catgaagaat accttagagg aagtacggaa gagctactcg cttatatcga agaacatcca
    26761 gtaaagggtg aatgttgtct gcttgtagaa gggaatttgt tcgaaatgcc agtgacggaa
    26821 gttgatgaag agttgggaac gttaaaggaa caagtagaag caaagatcgc ttcaggcgaa
    26881 aaaccaaatg ctgctatcaa agcagtagcg ctgaaaaatg ggctgaaaaa acaagaagtc
    26941 taccgtcagt accatgaatt agactgagat agtataagtt gtctataatg aaagactaat
    27001 gaggaaatca gctactaact tttcaaatct cttgaacgcg aacgaatgtt cttgtataat
    27061 gaataagagg tgaggatgat ggagctgcaa tttcctttac ataatgatac atcaagaaaa
    27121 atcattcata ttgatatgga tgcttttttc gcttcggttg aagaacgaga tcatcctgag
    27181 tttcgcggac atccattagt aattgccaga caccccagtg acactggtgg gcgtggagta
    27241 gtgactacag caaattatga agcaagaaaa ttcggaattc attcagcaat gagtgcacaa
    27301 aaagcgtatg agctttgtcc gcaagccatc tttaagcctg gcgaccatca taaatacagc
    27361 gatatttcca aacaagtacg ggaagtattc tatcgttata cagatattgt ggaaccagtt
    27421 agtatcgatg aagcgtatct tgatgtgacc gaaaataaaa tcaattgcaa gtcagccatc
    27481 aaaatcgccc gaatgatcca agcagatatt tgggagagtg tccagctaac atgttctgcg
    27541 ggagtaagtt acaataagtt tttggccaaa ttagcatcag actatcaaaa acctagagga
    27601 atcacggtag ttgcccctca agacgctgtg ccatttttaa aagctttgcc aattgaaaaa
    27661 tttcatgggg tagggaagaa aactgtacct agaatgcatg agctagggat ttatacagga
    27721 aaagacctat atgaatgcac agaaatgatg ttgattcgaa attttggaaa aatgggctat
    27781 tctctttatc gtaaagtcag aggaatccat gattctccag taaacgttac aagagagcga
    27841 aaatctgtgg gaaaagagca tacttatggg cagccgttgc aaacggaaga agcagtgctg
    27901 actcagttgc gccaactagc tgaaaaagta gaagaagcac tgagaagagt ccaaaaacat
    27961 gggaaaacag tagttttgaa ggtcaggtac acggactatt ctactgtgac caaaagagtg
    28021 acattgccag aatatatcta taaaaaagaa gcactctttt atcaagcaag ccttatatgg
    28081 gaggaaatct tgggagtaga aaaaggaatc cgattgttag ggattacttt gacgaatctg
    28141 gacccgatga cttatgaaaa catcgtcctt ccattatggg aaaatcaaga aatataaaaa
    28201 cagctttgag agttgaaacc ggaaatccgt tttctctccc aaagctgttt ttatatcaag
    28261 tcttgctttt tgatttgttc ataggtttct gttgcatccg tacatttttc ccaaatcaca
    28321 acttgattgg attctaaaga tttttggacg tcaatgatcc gctggttgct acttccgcga
    28381 aattgtagtt ttaggtcacg tttgcttaat tcaaagcgtc cgtcaacaag gatatcgatt
    28441 tgcgaaagga gttctaattt atcttctgaa tcttgtagca attcatcaaa ggtatagcct
    28501 gtccatgacc agatatcttt tgtcgtaccg aactcttttc ggatacgtcg tacgacttgc
    28561 agacaaacat ctgtattcaa aaaaggttcg ccaccaagta aagttaatcc ttgcacgtaa
    28621 tcgttgcgca agtcagcgat gatttgttct tctaattcag gtgtgaatgg tttgccatat
    28681 cggaaatttt gtgcagcttt gttgaagcag ccttcgcagg caaataagca gccactaacg
    28741 taaagactgt tgcggacacc ttcaccatcg acaaaattaa acggtttgta gtcagcaata
    28801 tagttttggc tgtagtcttt tgctaaccat tcttttggtt ttggatttct cataaaaaaa
    28861 cttctttcat ttaaggttca aagatatagc tattgaagat aaaatctact cgaccacata
    28921 aataagaaca aactgaccta aatccattgt tcaagaaagc ttgttcttat tttgatagag
    28981 ggcgttcaaa gatacaaagc catcgaaaga gggtggtgaa aaaagacttg tcatagcctc
    29041 ttattctgaa taaacggtgt tcaaaagctt gcatctgcag taataagccc aactaaacga
    29101 aaaatatgag gaactatttt tgtttagcta ttcttattac ttgatgcagg acagcttttt
    29161 cacaacctca tttcatgtgt ttcacacgtg aggaaatttc tttatggcgg ccatgtacca
    29221 tcggacgagc ttgcggattt cctaaatagc cacaagtacg tttgactaca tcacatgttt
    29281 ttggatcatg atttccacat tctggacatt cgaaccctcg ttctgtcggt ttgaaatcac
    29341 cttcgaaacc acattgatag caatgatcga ttggcgtatt cgtaccaaga tacccgattt
    29401 tgtcatatgc aaaatcccat acagcttcta aagctttcgg attttgttgg agcatagggt
    29461 attcacagta gtggatgaat ccacctgaac aatattttgg ataatccttc tcaaattcca
    29521 atttttcaaa tggcgttggg tttttacgca catcatagtg gaaactgttt gtataatatt
    29581 ctttatctgt gatattttcg atgatgccga atttttctgt atccaaacgg cagaaacggt
    29641 cagttagact ttcacttgga gttgaataga cactgaaatg ataaccatat tcatcccccc
    29701 atgcatctgc attagctttt aattctttga cgatatcaag tgtgaaagct tttgcttctg
    29761 ggtttgtttc ccattcgcca ccgaagaaag ctgaagcaac ttcatacaat ccaatgtagc
    29821 ctaacgatac agtagctcga cggtttttga ataattcatt gacagaatcg gtacgtgaaa
    29881 gacgtttccc gaaagcacca tacatatata aaattggcgc atttgctgga atggcttctt
    29941 tacaacgttc tacacgatag agaagcgcat ctttcatgat ttctaagcgg tcagacagta
    30001 actgccagaa tttattctga tctccttttg attcgatcgc gattcttggc aaattcaatg
    30061 taacaacacc taaattcatt cgtccgacat ttacttcttg accattttcg tctttccacc
    30121 cttgcaagaa tgaacgacag cccataggta ctttgaaact tccagttaat tcaacgattt
    30181 tatcgtaatt cagaatatca ggatacattc ttttcgttgc acattccaat gctagttgtt
    30241 tgatgtcgta attaggatct tcagggttta agttcacacc ttttttcaaa gtgaagatca
    30301 gtttagggaa gatagctgtc cgcttttcac tccctaatcc attgattcga atctgtaaaa
    30361 ttgctttttg aatttctctt tcaaaccagt tttctcctag tccaaatcct aatgaagtga
    30421 aaggagtttg tccatttgaa gtaaataagg tattgatttc atattccaaa ctttgcatag
    30481 catcgaagat atcttttttg gtttttgctt ttgcatattc tttttggcgt tctggcgaat
    30541 cgatccattc ttccgcgtct tttagatgtt ttttatagtt caattctgca aaaggagcaa
    30601 gcaattcatc tgttcggtcg gcagaacagc caccatattg acttgacgct acattggcaa
    30661 taatctgtga gatttgtgct gtggcggtct ggatagattt tggcgattcg acttcggcat
    30721 tgccgatttt gaacccattg ttcagcatgc ctttgaaatc aatcaagcag caattcgtca
    30781 tcggtgtata aggatgataa tccaaatcat ggtaatggat atcgcctttt tgatgcgcat
    30841 ttgctatatg tggtggcaac attttcagtc cgattgattt tccaacgatc ccggctgtca
    30901 gatctcgctg tgtattgaaa acattactgt ctttatttgc gttttcgttc acgacagttt
    30961 ggtccttgtt gattagcttt tcaatcgaaa agttgatatc tgttgcttta ctgcgagcaa
    31021 aatctcgttt ggtacgataa ttgatgtact cttctgctaa ttcatattcg tttttttcta
    31081 gtaatatatg ttccacgatg ttttgaatct catagatttt gacattttca gcaaaccggc
    31141 ttttgatttc ttggacaacc aagtctgcaa tcatttgaat tttttcataa gtaagtggtg
    31201 ataatgagcc gtgaattttc ttttctgctt tgatcagtgc ttcattgatc ttttgttcat
    31261 cgaaatcaac atggcggcca tcgcgtttga tgactttcat ctgggatgtc tctggctgct
    31321 gagtaacgac agttttttct tcataattta ctttcattat cttcaactcc tgctaaattg
    31381 ttcttgtcta tcataaaaca aaatcgggga aggagcaact aaatatcggc tatatatagt
    31441 attcaatgtg ctgtataatt ggatttctat actatatgta gtgtatattt tattgtgaaa
    31501 aaaggtgaaa acttgtagct ggtggatttg ttttttgcat atttaatttt gctgaataaa
    31561 ataattgaat aaaatttttt attcagtcca agtaaaagtg acaaaaacat aagagcaaat
    31621 tattcgtaga tatgctacta tgcaaataaa tagaaatgaa aaatgaaaga ggaggagaag
    31681 aattggaaaa gatgatcgaa gtgaaacatc taagtaaaag ctacggcagc aaactttctc
    31741 ccgtcaaagc cttagataat atctcattca cagtagaaga aggcgagttt gttgggatta
    31801 tgggcccaag tggtgcagga aagacaacgc tgatgaatat cttgtccacg atcaatttgc
    31861 ctacgatggg cagtgtctcg atccaaggaa aagaaatcac aaaaatgaaa aacagtgagc
    31921 tcagtgactt tcgtcgaaaa aaactaggat tcatttttca agagttcaat ttgatcgata
    31981 ccctaaatgc aaaagacaat atcctattgc ccctagcagt tgaacggatg actaaagagg
    32041 aaatggaaaa gagagtaaga catgtagctc aattgttgaa tatagaagaa ctgctcaaac
    32101 ggtatcccga tgaactttct gtcggacaga gacaacgaat tgcagctgct agagcacttg
    32161 ttgttcagcc acaagtgatt tttgcagatg aaccaactgg ctctttggac tcgaagtcgg
    32221 ctacagaatt gttgaactac ttgaagacca tgaatcaaaa agaaaaagca acgatactgt
    32281 tagtcaccca tgatccatat acagcaagct actgcgatag aattttattt attaaagatg
    32341 gtgtgatttt ttctgaagtt gtcagaagag ggacaagaag agagttcttt gagaaagtaa
    32401 tagacatgca ggcgacgatt ggcggaggag gaaaaatgaa tgctgtataa actagccgtt
    32461 aaaagttttt ttcggcagtc acgaggctat cttgtttatt ttttcagttt gactttatcc
    32521 gtaatgatct attattcctt cagcgcaatg acctacgatc aatctttagt cagaagagca
    32581 agtcaagata cttcgataga tggtggattg agttttggtg gatttatcat tactgttgtt
    32641 ttgctttttt tcgtattcag tgccaaccga tttttcttga atagaaggca aaaggaaata
    32701 ggcatctatc agctttttgg tatgaataaa ctgcagatat caggtatata tgtgttagaa
    32761 atcatgataa ttggattgtt cgcctgtatt tctgggatat tactcggtat tattttttcc
    32821 aaactctttt caatgatttt ggttcgaatg atggatatgg atcttactag tccatttttt
    32881 atctccattc catcagtagt agatacttta tttgcttttt tcatcatcct tttagcagta
    32941 tctgtatatt caatatggaa aatatggcgc tatccaatga ttcgaagttt tggagaaaaa
    33001 gaacaagcag atagttcaac aatgcgcttc aggacaaggc accgattact cgcagtcatc
    33061 gggttactac ttttaacgag cggatatttt ggagctagtc attttaggga aatcacttca
    33121 tggatgatca gttatcatta tcttgataca ttagttttct tttttccttt tttaattttt
    33181 ttcgtttgtg tggtcggtac ttatttgttt ttctgttata catttcggtt atttttgatc
    33241 atattgagta aatggaagat ttattactat ggtatcaatt ttttgataat gggtaacacg
    33301 caagttcatt tgctcaaaag ttggcgtaca aattctctga ttacagtcat tctcggaatt
    33361 tctttaatga caattggcgg cacggctagt atctctacta ttttatccta ccaggagaaa
    33421 gtttcctccc cgatggacta tcagtttgat gttgagacag agaaaaaaat caagccgatt
    33481 ctagcagagg aagggcagaa gataactaaa gaaatcacct tgcattataa agtcattggg
    33541 agtatctata gtcaaaatct cgaagaacct atgtttcaaa ctgctaatct gatcacggaa
    33601 acacaatatc aagccttcag aaaagttaat ccagatttgc cgaacatttc tttgaaatca
    33661 cctggtcata ctgttttgct tgatcaaatg caaactcttt ttcggaatat ttcattatat
    33721 ggatctagta ttggactgcc agataatcaa gaattgaaga ttcaacaaat gcttccaagt
    33781 gtattaggtg acgaaacaat ggtatatcta agtcctgtac tgattgtaga tgataccgtt
    33841 tttgaaaaag caaaaggtgt ggattatcaa gtagtcaatg tagatgtatc aggtggaaat
    33901 aatgaaaaaa tagatgaacg actgagcaat gacctgtcga taaagtggct caatgctgtt
    33961 tattattctt atgatatcgt aaatggaagt ctacaaggag aaattagcac aaagaaactt
    34021 ccggatgacc aaatgaagga agcacaattt agccaagaaa gctctcgttt gaatttctct
    34081 tccagctatt cgaaattgcg tgcagttaat cggcgaatcg gtatcaatat ttttgtcaca
    34141 ctatttgtcg ggatgatcgt gattattgct actggtagta ttttgacagt ccggcaatta
    34201 gcagaagcag aggaagaaaa agaaaattat cacctattga ctaagctggg gattccacaa
    34261 agaaggatca gacggatgat cttcgagcaa aacgcactta ccttctttcc acccatgata
    34321 ttagggatca ctcacgcagt atttgcaatc aatgtcttca ctcagtatat aaaaactgcc
    34381 gattactggt tggcttatct tgtgagtggc ttattgatcc ttatctatct tttgctttat
    34441 gtcattacga gtcagttata ttgtcggatt atcgaggaat gatatacgga ataagacaag
    34501 ataataaata gaactaaatt ttgaatacca tttatttgga ataagaggtt gtgacacgat
    34561 ttttgtcaca acctctttat tttttatatt ttttaaaagt acgagaaatt ataaagaaaa
    34621 aagcagtgat ttgatgtgct atttttataa aagctatgtg acaaaactgt tagtaaaaaa
    34681 acggtttctg taagctagac acatgtttct ttttgtcaaa attagttaca ctttgtgtga
    34741 ggttatatga ggagggaatc caatgaacaa atggcgttct aatccaaaat tgaattattg
    34801 gggaaaattc atcattcgaa caatttttta tagtgcagta ctgctgttcc tgatttatct
    34861 gtatcactat aaaaatattc aaggaggaac ttttatctat aacgaatttt aggaggaaga
    34921 gtatggaaat caaaacgatt attgaagcaa tcgatgattg gggaataaat gaacctgatc
    34981 gagttgctta tcaggcggat gagacgcata cttttggtga attgaaacaa gcatcagacg
    35041 cacttgctta ttatttagaa aaaaaggtag aaggcgatgg accaattgtc gtttttggca
    35101 atttggagtt tgaaatgatt gtctcatttc taggggttgt caaatctggc catgcctatt
    35161 tgccgattga agagcataca cccaaggagc gtatcctatc gatctttcgg gtggctaaac
    35221 catctatggt catcagtatc ggggactgga tagaagatat tccttcggtt cctgtcataa
    35281 caaaaaaaga atttcaagaa atcaagaaga taccagtagg attttatccc agaaatagcg
    35341 taaaaggtac agaaaatttt tatattattt ttacttctgg tactactgga gaaccaaaag
    35401 gcgtacaaat cagtcatgat aatctagtca gctttgttca atggacgatg gaagactttg
    35461 ggatcaagcc tggtatgcat ttcttagccc aagcgccatt ttcttttgat ttatcggtat
    35521 tttctattta tcctgcatta gtttctggcg gaatgctgaa gccgttaaat aaagcagttg
    35581 ttcaagactt tcgtcaatta ttcgcgacat tgccagcctt gaagttgaat gtgtgggttt
    35641 ctactccatc atttatggat atttgcttga tggaacctac attcaatgga gaaaatgtgc
    35701 cggaattgga catgttttta ttttgcggag aagaattgac gaaaaaaact gcagaaagtc
    35761 tacttgatcg attcccaaat gcacggatat ataatactta cggtccaaca gaagcaactg
    35821 tagctatttc aagtattcag attgaccagc atgtactaga tagttatgac cgactaccga
    35881 ttggctacgt aaaaaaagac acgaaagttt ctattgtcca agaaggtaaa cctgtttcaa
    35941 aaggagaaac gggtgaaatc attattgcag gaccaagcgt atcaaaaggt tacctgaaca
    36001 atcccgaaaa gacagctgct gcgttctttt gtcaaaatga cttagcaagt taccatacag
    36061 gggatgcagg tagactagat gaatatgggc ttttatttta tgaaggacgt atggatcagc
    36121 aggtcaaatt acatggatac cggattgaac tcggggatat cgaacattat ctgctccaag
    36181 acaaccgaat caaacaagct gtcgtcgtac caaaatacca aggaacaaaa gtacagcagc
    36241 tggttgcttt tgtcgtatta gaaaacaaaa cgaaacagcc ggattttcag ttgactaaat
    36301 ctatcaaaga acaattacta gaagttgtaa tggattatat gattcctcag aagttccatt
    36361 atgtcgatct gctgcctcag acagttaatg gaaaaatcga tcgaaaaaaa ttaacagctg
    36421 aggtgaatcc tgaatgatgt tacctcatat gatcccttat gcagagccgt tttatttttt
    36481 tcttttagcc attgcgcttg taccgatcgt tctatcttta ttgatatggg aaaaaagatt
    36541 accagtttat caatcagcag tgacactttt ctttttattt gtcagctttg gaggtaatta
    36601 ttggcaacag ggagcggcgc tgattgggta tgttttgtgg cagacgatac ttgtatgggg
    36661 ctattttgtt tatcggcaaa ggaaaaatca gacaggatgg ttttttgccg ccgttatttt
    36721 agcgataatt ccactgtttt taacgaaagt gactcctttt tttgaacatg gaaaagcatc
    36781 gttacttggt tttttaggaa tctcttattt aacctttaaa tctgtacaaa tgatcatgga
    36841 aataagagat ggcatgatca aaacatataa gccatttcgt tatatccagt ttctgctgtt
    36901 ctttccaaca atctcttctg gaccaatcga tcgctatagg agatttgaaa aagatcagct
    36961 ccatccgcct gttcgtgata aatatgttga tcttttggga aaaggcgtcc aaaatatttt
    37021 tgtcggtttt ttatataaat tcattatcgg ttattatttt ggtcaagtac tgcttcctgt
    37081 agtgggacgc attgccttac agcatggtgg tatttcatgg gcattagtag gttatatgta
    37141 cgtgtacagt atgtatttgt tttttgattt tgctggctat agcttatttg cagtcggtac
    37201 aagctacatg atgggatatc agacaccaat caatttcaat aaaccttttt tatcatggaa
    37261 tatcaaagaa ttctggaatc gttggcatat gacgctgtcc ttttggttcc gtgattatgt
    37321 atatatgcga ttgatgttct tcatgatgaa gaaaaaattt tttaaaagca agatcgtaat
    37381 gtcaaatatc ggttattttg ctttgtttct tctaatgggt atatggcatg gattgacgtg
    37441 gtactacatc gtatatggac tgtatcatgc ttgtctgatc tgtctgacag atgcatggat
    37501 ccgatttaag aagaagcata aagagcagtt gccttctaac aaatttacgc atggcttagc
    37561 cgtatttttg acatttcaag cagtatgttt tagcttcctg attttttcag gatttttaga
    37621 taaacttttt tttagctaac gaatagtgac atattaattt atataacaaa ggagaaaagg
    37681 aaaatggaag aacaaatttt atcaatctta gaagaaataa caggaacaga tgaagtaaga
    37741 aaaaatcgtg atattgatct atttgatgaa gggttgcttg attctttagc atctgttcaa
    37801 ttattagtcg agctagacgg agagctggat atccaagtcc ctgtatctga attcgagcga
    37861 gaggattgga gcacaccgaa taaaatcatt caacaagcaa ctgcattgaa gggttgagta
    37921 tgaaaaagaa actttttgct attttcggcc cggttgtttt agctgttggc ttactgtttg
    37981 tgttttttac ctcctcctat caagtagata tctctaatcc agaaacgatt agacgtgcct
    38041 cttcttccat gtcagtgaac gtgttgaaag gagatgcgat aaaaaattat gcattatctg
    38101 aaaaacaata tattcctttt tttggctcaa gtgaattaag cagaatcagt ccatttcatc
    38161 cgtctgttct ggcagaaaaa taccagcgaa actatcgtcc atttttgctg ggagcacccg
    38221 ggacacaatc gttaagccaa tatatgatga tgcgttctgc aggagatgct atgaaaaaca
    38281 agaaagtcgt ctttattatt tctcctcagt ggttcgttaa aaatggtgta aaaactgatt
    38341 actttaatac gtattattct gaacttcaaa catacgactg gttgttttca atgaagaaag
    38401 taacgcctgc tgatcgctat ttagctagaa gattattaac tttctcaaaa gtaaaagaga
    38461 atgatacgtt gacggcgatt ctgcaaacga tcaaaaaagg gaagctacct ttacctgaat
    38521 ctttgaatca gctgcgcagc caatggaaca tgctgaagag agaggatgaa gtattcagca
    38581 atattgggtt gaaagatcga cagcaaaaaa tcgatcatga gtcaaaacga ttaccaaaac
    38641 aataccaaga aacagaatta tccattttag caaatcaaat tggagaacga gaaacgacga
    38701 ataatccatt cgggttgaaa aacgattttt atacgcatcg tatccgagcc cacgagccag
    38761 agctcaaaca gtcacaaaaa aattgggatt atcgtttttc gccagaattt tctgattttc
    38821 agctggtctt ggatcaatta gcaaaaaacc ataacgaagt attgttcatc atcccaccgg
    38881 ttaacgagaa atggagcgat tataccggac tatctcaaga aatgttacaa ggatttgcca
    38941 aaaagatcaa atttcaatta aatagccaag gattcaatcg aatagctgat tttgtcaatc
    39001 aagcgggtac caactatttt atggaagaca cgatccatct aggctggaaa ggctggttgg
    39061 ctgcagatca acagatcaga ccgtttttag aagaaaatca tattactgct agtaagtatc
    39121 atcttgacga tgcttttttt agcaaatctt ggcaacatca aataccagat aaactacaat
    39181 taaaataaag aaaacaggcg agtgttgctc gcttgttttc tttatttttg aatattctga
    39241 ataaaagata aaaataccaa gtttgcctga acaaaaatca taagcaatgg tataatcaca
    39301 atatgaatat agaaatgggg gaaaacattt ggatacaaaa gaagaacagc tacttattga
    39361 tttaacttct gcaaaaggag tacctggaaa tgaagaagag gtaagagaag tattcagaga
    39421 atatgccaaa ccattcgctg atgatatttt ttatgacggt ttaggcagtg tgattgccaa
    39481 acatggtgct ggcggaggcc ccaaggtctt tatttctgga catatggacg aagttggttt
    39541 tatggtaaca aaaataaccg aaaaaggatt cttggaattc caaactcttg gaggttggtg
    39601 ggggcaagtc atgcttgctc agcaagttga aatcaaaaca cgtgaaggga aaatcgtcca
    39661 cggtgtgatt ggttccaaac caccacatgt tttaacacct caagtaagaa ataaacctta
    39721 tgaaataaag gatatgttca ttgatattgg cgcatcaagc caagaagaag ccaaagagtg
    39781 gggcatacgt cctggagata tggtcactcc atatattgaa tacaaacgaa tgaatggcag
    39841 taaatattta ctggcaaaag catgggataa tcgtatcggg acagctgttt ctctgcgagt
    39901 attagagaat ctatctaaag aagcacaccc aaatgtttta ttcgcaggaa gcgatgtgca
    39961 agaagaagta ggcttgcgag gtgctcgaac aagtacacac cttgtaaatc ccgatattgc
    40021 ttttgcttta gatactggta cagcaggaga cactccagga atgacaccaa aagaagcaga
    40081 ttcgatttta ggaaaaggcc cacagatttt gatttttgat gcatctatga tcccgcataa
    40141 aaaattattg aattttgtta ttgatgtagc agaggaaatg gatattccat tccaatatac
    40201 agtgatttct ggcggaggaa ctgatgcagg acaaatgcat ttgacaagag atggtgttcc
    40261 gtctgtagcc attaccgttc ctgttcgtta tctgcattcc catacatcag tgattcatga
    40321 agatgattat ttgaatacag tgaaactagt cacagaatta gtgaaacggc ttgatagtga
    40381 aacagttgaa aaaattcgga gttatgaata atgaataata gaata
//
LOCUS       DAXLPC010000016        36706 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.016, whole genome shotgun sequence.
ACCESSION   DAXLPC010000016 DAXLPC010000000
VERSION     DAXLPC010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.016"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..300
                     /locus_tag="ACF3UE_000795"
     CDS             <1..300
                     /locus_tag="ACF3UE_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFD3634251.1"
                     /translation="DGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKEN
                     RKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(653..1501)
                     /locus_tag="ACF3UE_000796"
                     /pseudo
     CDS             complement(653..1501)
                     /locus_tag="ACF3UE_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1654..2766
                     /locus_tag="ACF3UE_000797"
     CDS             1654..2766
                     /locus_tag="ACF3UE_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFD3634252.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(2844..3137)
                     /locus_tag="ACF3UE_000798"
     CDS             complement(2844..3137)
                     /locus_tag="ACF3UE_000798"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFD3634253.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3305..3619
                     /locus_tag="ACF3UE_000799"
     CDS             3305..3619
                     /locus_tag="ACF3UE_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFD3634254.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3640..5619
                     /locus_tag="ACF3UE_000800"
     CDS             3640..5619
                     /locus_tag="ACF3UE_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3634255.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5632..5958
                     /locus_tag="ACF3UE_000801"
     CDS             5632..5958
                     /locus_tag="ACF3UE_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFD3634256.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            5974..6492
                     /locus_tag="ACF3UE_000802"
     CDS             5974..6492
                     /locus_tag="ACF3UE_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634257.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6492..7844
                     /gene="celB"
                     /locus_tag="ACF3UE_000803"
     CDS             6492..7844
                     /gene="celB"
                     /locus_tag="ACF3UE_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFD3634258.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(7928..9433)
                     /locus_tag="ACF3UE_000804"
     CDS             complement(7928..9433)
                     /locus_tag="ACF3UE_000804"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFD3634259.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9525..10115)
                     /locus_tag="ACF3UE_000805"
     CDS             complement(9525..10115)
                     /locus_tag="ACF3UE_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3634260.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10294..11940
                     /locus_tag="ACF3UE_000806"
     CDS             10294..11940
                     /locus_tag="ACF3UE_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFD3634261.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            11989..12708
                     /locus_tag="ACF3UE_000807"
     CDS             11989..12708
                     /locus_tag="ACF3UE_000807"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFD3634262.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13187..14134
                     /locus_tag="ACF3UE_000808"
     CDS             13187..14134
                     /locus_tag="ACF3UE_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3634263.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14146..15066
                     /locus_tag="ACF3UE_000809"
     CDS             14146..15066
                     /locus_tag="ACF3UE_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3634264.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15107..16564
                     /locus_tag="ACF3UE_000810"
     CDS             15107..16564
                     /locus_tag="ACF3UE_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3634265.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            16909..17523
                     /locus_tag="ACF3UE_000811"
     CDS             16909..17523
                     /locus_tag="ACF3UE_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFD3634266.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17516..19240
                     /locus_tag="ACF3UE_000812"
     CDS             17516..19240
                     /locus_tag="ACF3UE_000812"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3634267.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19237..20688
                     /locus_tag="ACF3UE_000813"
     CDS             19237..20688
                     /locus_tag="ACF3UE_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3634268.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21161..23314)
                     /locus_tag="ACF3UE_000814"
     CDS             complement(21161..23314)
                     /locus_tag="ACF3UE_000814"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFD3634269.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23316..24362)
                     /locus_tag="ACF3UE_000815"
     CDS             complement(23316..24362)
                     /locus_tag="ACF3UE_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3634270.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24512..25801
                     /locus_tag="ACF3UE_000816"
     CDS             24512..25801
                     /locus_tag="ACF3UE_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFD3634271.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            25814..28516
                     /locus_tag="ACF3UE_000817"
     CDS             25814..28516
                     /locus_tag="ACF3UE_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFD3634272.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            28501..29358
                     /locus_tag="ACF3UE_000818"
     CDS             28501..29358
                     /locus_tag="ACF3UE_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3634273.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29429..30286)
                     /locus_tag="ACF3UE_000819"
     CDS             complement(29429..30286)
                     /locus_tag="ACF3UE_000819"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFD3634274.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            30497..32668
                     /locus_tag="ACF3UE_000820"
     CDS             30497..32668
                     /locus_tag="ACF3UE_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFD3634275.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            32736..33077
                     /locus_tag="ACF3UE_000821"
     CDS             32736..33077
                     /locus_tag="ACF3UE_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFD3634276.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33353..35107)
                     /locus_tag="ACF3UE_000822"
     CDS             complement(33353..35107)
                     /locus_tag="ACF3UE_000822"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634277.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35118..35954)
                     /locus_tag="ACF3UE_000823"
     CDS             complement(35118..35954)
                     /locus_tag="ACF3UE_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFD3634278.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(35956..36639)
                     /locus_tag="ACF3UE_000824"
     CDS             complement(35956..36639)
                     /locus_tag="ACF3UE_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFD3634279.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        11843 a         6446 c         7481 g        10936 t
ORIGIN      
        1 gatggcttag caccaggagc atatcagctg gtagaaactc aagcgccaac ggggtatgaa
       61 ttggatgcga caccagtaac tttcaagatc gaaaaagaac aagaagtggc gatcttttta
      121 acaaaagaga atagaaaagt tgctgatagc tcagatataa gaggaaacaa tccaacaagc
      181 agtggaaata agcatcttcc aaaaactgga gaaaccatca ttagccagtt tatattgtca
      241 atattgggtg tgctacttgt tttcatcagt ataaaattta gaaagaaacg aaatatatga
      301 gctaaaataa aaaattgaat aagcatagtt tttaaaatca actagtaccc atcaattgaa
      361 tggaaactac cgattttaga aggggtatac aaacaaatat tagtatcgga gtagagaagg
      421 ttgaacccaa ccagtaaata agtaaagaca attttgtgct gcgttgagaa gtgaaaaata
      481 aacctttgta gtaatactag ttaataaaaa atatacaaaa acactgcgaa aatcattctt
      541 gagtttcgca gtgttttttg cctaatgact caagtttatt gggtaatact ttgattttct
      601 ttctacaaat aatcagcgat cagttgtaat tttttctcta gttttaatgg ctctttgtca
      661 ataaggagaa aaacaagtcg ggtcttttgt ctcggaaagc ttcaaccaac tcgtgaataa
      721 aggttacgcc tccttgaaag gcgtggaaaa accaagtaat cgatcaatca ccaatttcgc
      781 atttggtaga acatgtttgg tgagctgaaa gtaggtggcg ttcatgtctg taactaagaa
      841 ttctatttct ttaggattag tgcagctaag gaaatagttt gttaatcgag gaattttttg
      901 tgtaggtaaa ttttctcgat taatttttct gtctcgccat ccgcggaaat aaaactcagt
      961 ttatcctcaa cggaaacgtg agaacgaaat tcacaaccct caacactcaa gacagaattc
     1021 ttttggaaga ctttggtaaa tagcttctca actctttcaa tgtgcgaata acggttgtca
     1081 aagataccta acaacttttc gaaataaaaa ataacgacac tttttcagtc agtaaagaag
     1141 tgattttatg tctgacatga tttgaaatcg agtgccttgg acggataaaa taactttgag
     1201 cgttccaatg gcttcgacag tttttacagg tatagcgctg cttttttagg cgtataacca
     1261 ttggcatatg attatattat tcaaagtgga caatggtttc cttcttcttg tttttcacca
     1321 ccattaattt cctatttcca tctaccacag cagaaccaca atttctacag acacatggag
     1381 cagggaagag aactgcagca acgatcaatg tttttttctt ctgtaaggtt tcgtaagaga
     1441 cctctgtaat catcaaattt ttgtctattg atctcagaat ttttttgata gaaccattca
     1501 taaagcatat cgttctctca gttgtttatt ttgtggtgat ttaatcatac aagaaaacga
     1561 tatgtttttt tataaaaaca tgaataggaa aaatagttga caagaaaatg acaacgccat
     1621 atgatgttcc atagtattta caacctgtca tagatgactg taaaaaataa aagtaaaaag
     1681 aaaggacgac aacaggtgga tttttatcag tctctacaac tagatccgtt tattttaaaa
     1741 caaaaaatac gagaagcagc ttctaaaaaa gaaaagtgca tgtatatttg ttcattgttt
     1801 ttacgatcat tattcatcgt attgtttgcc atttgtttta tcattataat tacaacatta
     1861 tttgaatcga agcataaacc atacgctgtg gttttattct gtatgttgat gagtattcgt
     1921 tttgttgact ttggttataa gatttcccat tcgatcatag gtttagcaat cgtcatgttc
     1981 tcactattag tagcaccgta tgtccagctg atcaaatggt cagttatggg catgttgatt
     2041 cattttattt tactaagcag catattaatg gcaaccgcta gtgatcccaa aatggggaat
     2101 gcttctttgt acggcttttc atatctcttt attgtttatt cgttacctaa agattcgttg
     2161 aacaagaatt tctttacaca aacaagtagc ttattatttt tgtttttttg ttggttttca
     2221 gttcttcttt acagaaaaca tcgagaaaag aacaaagaca aaagcttgtt taaagagatt
     2281 tttttgaaag gcatgtattc gcaggaaaaa atttggatgc tcatctatgc atttggcatt
     2341 agtcttttga tcgttgcagg agagtatgtc ccttttcagc gattgatgtg ggcagggttt
     2401 gcattttctt ctattgtatc tagctatgga ttgatgtcga ttggtttcaa agaacgagca
     2461 gtagaccgaa tcattggctc attgattgga tgtgttttat ttattggtat cagccaattt
     2521 attcctttta actgggtcgg tatattaggt ggtctagctt taggtgtttg ttctacctat
     2581 agatataaaa cagtttttaa ttcttttggt gctttggcaa tcactgccag tttattcggg
     2641 gttccaggag cagtaacgat ccgcattttt gagaatatcc ttggggtatg tttaggaatc
     2701 atgtatattg gggtgactga aatacttatc cgaaaaataa gagaaaaaca cggtttgaat
     2761 cattagatga gatcgaataa aaaataagga aaaagtgaag atacacatgg atgataaatt
     2821 gctatcattc catgtgtatc tttttacggt aaatcagtga aacgttcgac tttcattttt
     2881 aatttatact ttttacggag ttcgtttatt tgagccatca tttcggattt gtgatgcttt
     2941 tcgattgctt cttcatcttt ccaacggtcg atcagtaaaa gagattctgg atcttctagt
     3001 ggaaagtaat agtcatattt ctcgtttcct tcttctgcac gaatcgcttt gacaatgttt
     3061 ctttcgacca tttcttctgc aaattttctg gcttgtccat ttgtacttgt atacaaaata
     3121 ttcactgtga tactcactaa atcccctcct gaaaaaattc tatcactagt atatcacggt
     3181 gccagaaatt attattcaag atatgataca cattttttcc gcaatgctac ggaaatatat
     3241 attttgaata gaaaacgctt acaagatatg cttggtttat aaaaataaaa ggagtgattg
     3301 atttatgaaa aaagcattga ttatttgtgc ggcaggaatg tcatcctcga tgatggcctc
     3361 aaagacaacg gatttcttta agcaaaaaag agaagaggta ctcgtagatg cagtttcagc
     3421 tacagaaggc gataatatga ttaagaatag tgattttgat ttatttctga tcagcccgca
     3481 aacgacgatg tttttggata aattcaaaaa attaggagaa tctgttggaa agcctgttgt
     3541 tagtatccct ttccaagcgt atgtcccaat ccctacaggc atccagaagt tagcagaggt
     3601 gatcgaagag aacatatgat ggaataggag tggatgataa tgaaacagaa ggaaaaattg
     3661 ctgttgagat atttgattga tcacaagaag gagtatgtca ccagtcaacg tttagcttct
     3721 gaattgttat tatctgatcg gacaatccgt aattacttgc agcggatcaa agagttagta
     3781 gaaaaaaacg gaggtaagat cattgctaaa ccaggttatg gctaccaact gcatatttta
     3841 caaagactga catttgactt gtttttgagt cggcaagaaa tagtacctgg atatgctaga
     3901 gaaccgcaag gattttatga gtccgaagat cgacaaaagt atatattgaa ccaattgctt
     3961 ttggaagatg ccattctttt tatggatgat ttggcagaag agctttatat cagtcgttcc
     4021 agtttgacaa aggacatgca agaaatcaag gagcgattga ttccatattc actaaaaatc
     4081 gtttctaagc atggtcaagg gacatggatc gaaggggaag aaagaaatcg acggcatttt
     4141 atcatggata ctttttttgg aaaccattat ggaaattcat tgaaagaata tttagggcaa
     4201 agccgttttt tcccagacat cagttttgaa gagctagtca ttatcattct cgatgaaaca
     4261 agagaagcta agttaaaagt ttcggatttt atcatacaga atctgacttt acacttggct
     4321 ttggggatca aacggctccg agaagggttt gaaatcaagg aattaggcat cgaacaagaa
     4381 gtttctaagc gagtagagta tcaagtggcg cagcggatcg ttcaacgtat tgaggtaatc
     4441 gcaggtgtat cgtttcccga agaagaaatt gcttatttga cattacatct catggctaag
     4501 tcgaatcaca aagaaaatca aaatgatcag gaactatcaa aggaattagc gaaagttctg
     4561 aaaagattgt ctcaggaatt tcatttttca ttagtagagg atctccagct tttcaatgga
     4621 ctactcgatc atttgtcacc gatgatgatt cgattgagcc gaggtattcg cattgagaac
     4681 ccattgactg aggagataaa gaaagaaaat cccaaagtct ttgacgcagt aaaaaggcat
     4741 ttcagcaaca tgccggcttt gaaaaactat accatcaatg aagatgaatg ggcctatttg
     4801 gctttgcatc tcatggcggc attggaaaaa gaaagagctg cgcataaact acatgcattg
     4861 attatctgtg caacgggtta cggcagtgcc caactattaa agaatcgcgt agtcagtgaa
     4921 ttcggtaaaa atattacagt ggtaagtgta aaaggctatt atgagatcaa tgaaacaact
     4981 ttaaaaggaa tcgacctgat tatttcttct attgatcttt cgacaatgtt tttcaaaatt
     5041 ccagttttac atgtcagtat ttttttgaat gaagatgatg ttcgtaaaat acgaaaggta
     5101 gttggagaat ctatacccta tcattcctca gatagaccga taccagcatt ttctctacag
     5161 caaaaaaagc agatttacac cgaacagttg tctgaaaaat ttttcaagac ttatacgtac
     5221 gaaccgaaaa aggaagaaat tcttcatgat ttgctgcaaa agctgagcat aaatgaagaa
     5281 gaaggatata taagagaaat gcgaaagcag atccagcaac gtgaaaatat gggacaaatc
     5341 atattcagtg atacagtggc agtcccacat cccgctgttc cagttggaat cgaaacaaag
     5401 gtagccgttg cattgattcc ttctgggatg cagtgggatc aatatcaaga aattcatttt
     5461 gtttttttag tttcgccttc ttatgtcgaa aatgaaggaa ttacggtcgt gactaaagca
     5521 atcgttaggt tagttgacca gctaaaagta cagcaggaaa tcttagctga acctattttt
     5581 gagaatttca gcagtaaatt tatcaaactg atcgaataag gaggaaaaca gatggctgaa
     5641 aaaataaaca gtgaaacact acaagtgact tcttttgata tcattttcca tagcggaaat
     5701 gcacggacac tgatacatga agcatttcgc tcgatgcgta aagagatgtt tgaagaagta
     5761 gaagagaagt tgcgacaagc aaatgaagag attcttcatg cgcatcagtc acaaactcaa
     5821 cttctgaaag aatatgccag cgggacaaaa atagaaatgg aaattatcat ggtccatgca
     5881 caagatcatc tgatgacgac gatgacatta ttggaagttg cacaggaaat gaattatttg
     5941 tatcaaaaaa ataaatagaa aggaaggatc attgtgcagg atacagtaaa aaggaaaatc
     6001 gaattagaaa aaaagcaact tagtttgaaa aacatgtatt tcaatcgtta tctaatcgta
     6061 cgttacctga ctgccttttt ctttttcatg aacatgcaat ggatgattct gcttctatca
     6121 gctaaaagtt taggaagtag tttaccgatg attctgattt tagctatttt gcctgcagta
     6181 ggagaacaag taaagcttta tcgaaaacac caaacgaacg ttccatggac aaagtggtat
     6241 tttttgttcc agagtgtctt taatttatta gtgattccag tgttgtttac ctcaggattt
     6301 acattcttgt atccttttat ggcaaataac aatggaggac agttatttgt tttcattctt
     6361 gttgtaagcg gtatttttgc cagtgcattt atacagtatc gtttaaagaa aatttcactc
     6421 aaccaagacc aacagtatat ccgtattaaa caatatgaaa aagcgttata tttaggaaag
     6481 gagaataact aatgtttgat tttttgcaga aatacctgat gggacctatg gggaaaattg
     6541 cgcaacttaa aatcgttcgg gctgtcatgg cagcggggat ggcttctatt cctttcacga
     6601 ttgtaggctc gatgtttttg gttttaaata ttttgccatt accgttccca tttttagaag
     6661 gattttttaa tgcaactttt ttcaaagtta gtgacttgta catgatcgtc aatacaatga
     6721 cgatggggat tttatctatt tactttgcca ttgtgtttgc ttatgaatta acgtcaattg
     6781 aacgagatga acaaaaatta aatgttaatc cgctcacggg ggcattacta tctgtttttg
     6841 cattctttat gtgtatccct gaattgatca tgactgatgg taaaatcagc ttgattgctt
     6901 ctatcaatga gacagaaact gtagtaaatg gtattaggat gggctctttt gtcgaacgtt
     6961 taggaacttc aggaatcttt acagctatta ttatgtcgat tattgcggtc gaattgtatt
     7021 gtatgtgtgt caagagaaat tgggtcataa aaatgccaga tgttgttccg ccaggagttt
     7081 ctcgttcttt cactgctctg atcccaacat ttgtcattgc gtttgtggtg atgatcatca
     7141 atggattatt agttgcacta ggaacggata tcttcaaaat gattgctatc ccatttgggt
     7201 ttgttacgca gttgacgaat acatggcttg gtgtcatggt gatttatttc ttgatccatg
     7261 cattgtggat cgtagggatc catggagcga atatcatcac ttctttcttg accccgatcg
     7321 tattagctaa tatggcagct aacgcacaag gcgcaaatta tccgttggca ggagaattca
     7381 acaattctta tgtaaccgtt ggtggatcag gtgcgacttt aggattgatc atctttattg
     7441 cattcctcgc gaaatctgat cagctgaaag tgttaggaaa agcctcactt gtaccaggat
     7501 tattcaatat caatgaacca atcattttcg ggatgccaat cgtctacaat ccctatttag
     7561 cggttccgtt tttcttagct ccgatggctt ctgctacact cgcttatttt gccattcggc
     7621 tggaaatcgt caaaccgatg cttgcacaga tgccgtggcc ttcaccagtc gggatcggag
     7681 catttgttgg tagtggtggt gattggaaag ctgctgtgtt agcagtcatt tgtgcaatca
     7741 tcgcattcat tatctggttc ccatttatca aattctatga taataaatta ttaaatgaag
     7801 aaagagaaaa ggcagcagaa ttagctagtg aaaagttaaa atgatttcta agaaaaaagg
     7861 aactgtgaca aaaaatcaca gtcccttttt ttcttagaaa tgggaaacca ctagtatata
     7921 aataccatta ttcttcaatc aaccgcttca cgattgcata atccccttca taaggttcat
     7981 ctacaccatt gattttttga tagggatcca cgccttttcc cgcaataacg actgaatctt
     8041 gcggagcgct ttctgctaaa gcgcgtcgaa tcgcttcagg acgatccatt tcataatgaa
     8101 cgatcaaatc tggattagta attgcttcat tgatttcttc cgcgattttt ttcggatctt
     8161 caaatgctgg gtcatctgcc gtcaaaaagg cgatgtcagc tgtttctgat agcacttttc
     8221 caaaatcatg tcgacgggag attgctttgt ttcctgggct gcctaataca acaattacac
     8281 ggccatctgg atgttcattt ttggcaaatt ccagcaatgt tttcaagctt agataattat
     8341 gtgcatagtc cacatagaca tgcgctccat tggattggat caattgatcc attcggcctg
     8401 gtacacgagc ttcttttaat ccgtcttgtg catcttgact ggaggcacct gttagtgctg
     8461 cggcaatgat cgcactggct gcattttctt ggttgaatcc tccagccagc aaaatatcat
     8521 aagcagtatc gcagatagct aagcgatctt catgagaaga taaagtaaaa ccgtgagtac
     8581 ctttatctga acggatcact tgataattgc tttcttccga acgaccataa gtgatcgttg
     8641 gaatctggaa tagatcggct gtttccctaa gtaaatcaaa atagtcactt tcatgattta
     8701 aaacaactgt ttttgaattc aagatcaatt gtcgcttgca atagaaatag tcatcaaatg
     8761 tcggatgttc gatcggactg atatggtcag gcgagatatt caagaagatt ccgacatcta
     8821 aagtcaagcc gtatacgcgt tgtgttttgt aagcttgtga agaaacttcc atcactagat
     8881 gagtcatacc attttcaact gcttctgaca tcatacgata taaatctaat gactcaggcg
     8941 ttgtcaaatg ggatttgaaa tatgttttgc catctaacgt tgtattcata gtagaaagca
     9001 atgctgtttt tttatttgtt gtgtgatcca agattgcttt tgtaaagtac gcagcagttg
     9061 ttttaccttt tgttccagtg aatccgatca ctttcaattt attttgcgga tagtcgtaaa
     9121 aagccatagc aagaagcgcc attgctttac ggatatccgt tacgatgatt cctactgctg
     9181 aattttcgta tggttgttct gatacataat attgaatacc ctgttcgatt gctgaatcca
     9241 aatattcttc tttgaaattc attcctttac agaaaaacaa agtagaagca tcagcttttc
     9301 ttgaatcata acttaactga agaaattcag ctttttctgg tacatcaaga tgccagcctc
     9361 ttgttgaaac aaattctttt aatagatttt cttttaatag taaatgacgg atgtcttcta
     9421 aagagaagct cattgattga tccctcgctt tattcaattt cttggtttat tatagcacac
     9481 tctttttaat atatcgtttg tttccgctat gacaaaatcc agctttattc aaattttctt
     9541 gacacagggg acaagcggat gagtattttc ataaacaatg aactgactgt aatagatagg
     9601 agaacgaata gtgtctccaa caatccaaaa acataataat tcaaaaagac gataagacta
     9661 ttggtaagta aaagtccttg cggcattgga agccgaaaaa atttgtggaa aataatcggc
     9721 ggtatcgtta taccgccatt tgaggccccg actgtgtaca atgtgtaaac cccaagactg
     9781 aacaaaagac ttcctgaaat cagtgaaaag aaatgtgagg agatcatttc cacttttgga
     9841 acaatctcta aaacaacagg aaaaagcaga cttcccgcta cagtcttaaa aaatactgat
     9901 tttcctaata ggacagcggc tagaagcagc atcataagat tgatgctcca aacagtaact
     9961 gagcgttgga tagaaaaggc cgtttcaact aaatgtccga tggcgcccac tccggcggaa
    10021 gctatatcgt gagggagcaa gaaccaattc aatccaactg tgataaagaa aagacctaaa
    10081 aatataacgg gtagtttttt tatttcttgt gtcattgata tctcctataa atgttagcca
    10141 taaaaggctg tatatttctt tactttacca aaaaaacgaa accgaattca aaaaaacaat
    10201 tgttcttata aaagttatat aaaatcgatt gccagtttct gttttaccaa ttaaaatgat
    10261 agtaatgttt tgtagaaagt tggaatctga ccgatggata atcaaagaaa accagcatta
    10321 gatcaattaa caccgcaaga aaaaatggca cgaggctctg cttggatgac cgccagtaat
    10381 atcatttcaa gattgctagg cgctgtctat atcattccct ggtatgcttg gatgggcgaa
    10441 aatgctaagg ctgccaatgg attattcaat atgggataca atatatatgc attgtttcta
    10501 ctgatctcta cagcaggaat acctgctgcg attgcaaaac aaactgcacg ctataattca
    10561 ttgaatgaat atggcacttc acgacgatta tttatccgtg cattacagat gatgggcggg
    10621 ctaggcctgt tgtttgcttt gttcatgtac atcgcctctc cttggctagc tcatgcttct
    10681 ggtggcggag aagaactgat tccaacgatg cgttctttga gtatcgctgt attggttttt
    10741 ccttgtatga gtgtgatacg agggtatttt caaggcaatc aagaaatgat gccttatgcg
    10801 ctgtcgcaga ttgtagaaca ggtggcacgt attttttata tgctattggc tacattcatc
    10861 atcatgaaag tcatggatgg tgactatgtg acggcggtca cgcaatcaac tttcgcggca
    10921 tttatcggta tgctagcaag tattcttgtc cttttgtatt ttttgaagaa acatcaagcg
    10981 tatacatcgg cgtttattca ctacagcgaa aacaaaataa atattgcaac gaaggaattg
    11041 ttgttagata ccgttaaaga agcgattccg tttattattg tgggttcagg ggtaacgatc
    11101 ttcaaattag tcgatcagtt cacttttatg aagatcatgt ctgcatccac cgagtattcc
    11161 aatgcacagt tactggatct tttttcgatt tttagtgcca atccagataa gttgacgatg
    11221 gtagttattg cattggcaac atcgatcgcg tctactgggt taccgttgat tacagaagct
    11281 gttacgttga aagatcgagt aggtctggca aaattgacaa gcggaaattt acagttgttt
    11341 tcatttttta tgtttccggc gacatttggt gttatgttac ttgcctatcc gctaaataca
    11401 ttattttata caccggattc tctaggaagt aatgtactga tccaagcaag ttttgtagga
    11461 ctcttcctag gactatatat gctagtttcc aacatgctgc aaggaatgtt tgaaaacaag
    11521 gcggcaatta attatttggt tattgggttt ctagtgaaac tccttcttca atacccagcc
    11581 attcgtttat ttgaagtata cggcccttta ttggcgacaa tgatcggatt tgctgtgtct
    11641 tgtaccttga tcttaaagag aatccatgaa gtagcccgct ttaaaccaag ttttgtctgg
    11701 cgcaggacat tgctgatctt tattcttacc ttgattatgc ttttggcttc gtggatcaca
    11761 aagatgattt ttggtgcttt tttaaacgaa gatagcaaat tccagtctct attgttgatt
    11821 cttgtagtag caggtatagg ggctttagtg tatggttatt tagctttgaa aatccgcttg
    11881 gcagaaagac tactaggacc aggaatagcg cgtttacgac ataaattaaa aataaaataa
    11941 gtgaatcaga agagctagat tgatgctctt ttgaaatggg ggaaacgcat gcgtttagat
    12001 aagtttttag cagatatggg acttggcagc cgcaaagaag tcaaaggatt gatcaaaaaa
    12061 ggaacgatcg aagtcaatgg acaagtggtg aaaagcgata aagcgcaagt aaatgaattc
    12121 gaagatgcgg ttacttattt aggagaaatc attacgtatc aaaaagattt ttactacatt
    12181 ttgcataaac ctgcaggagt catttctgct actcaggata atcatgatca aaccgtaatc
    12241 gatttattgg aagaccagga ttatcgggaa gatctttttc cagtcggccg attagataaa
    12301 gacacagagg gcctcttgat tttaacgaat gacggggtgt ttgcccatca gttactatca
    12361 cctaaaaaac atgtggagaa agaatatcta gctgaggtta gcggtataat gacagaagaa
    12421 gatatccgtt tatttgcaga aggactgatt attgatggcg atgagcagac attgccggca
    12481 aaactccaaa ttgatcaagt agatcaagag acagaaactt caattatccg tctgattttg
    12541 catgaaggaa agtttcacca agttaagcga atggtcaaag cagtaggaaa agaagtctta
    12601 tatttaaaaa gaatccgtat gggaaaattt tggctgccta aagatttgaa taaagggcaa
    12661 tatcgaccca tgaccaaaga agagctagaa caagtgagag aaaaataatt gaatggatag
    12721 ctaaaagaat aagcagagta gttgtagcgc catctgaaaa gcagacttgt ccgtctgact
    12781 ttcggatggc ttttttgtga aatttcggct tatttccgta gaagctactt ctggaacacc
    12841 gtttgttcgg aataagggac tgtgacaaga cttttgttac agtccccatt gttccttgtg
    12901 actcagagtt agatagtaag gacacgatct ccctaatact caggccaaaa cgctgaattc
    12961 acaacctctg ataaacggtg ttcaatcagc tgaccctcgg tattagctca aaaaacggca
    13021 aaatatgagg aactattttc ccgttttttt ctctaatact caggccaaaa cgctgatttc
    13081 acaacctctc ctatactttg tttcattttc cctatacttt gtttatttat tctcattatt
    13141 gaaagcgcta taattacgtt gcgaatgaat cgaaaggggt ttttagatga aaaaacgaaa
    13201 ggggttcaat cattttttta tgaatctatg gcgttataaa gcacttgtcc tgatggctgt
    13261 accgggtatg ctttggatga tttttttctt ttacatacct gtaatggcga atgtcgtagc
    13321 attcaaaaat tttcatattt cagcagatgg gttcttggct agcttgaggg aaagtccttg
    13381 ggtgggttgg gaaaatttca aatttttatt ttcttcggat caagcatttc tcatcactaa
    13441 aaatacaatt ttatataatg tagcatttat ccttttgaat ctgctgatct cagtcgtatt
    13501 tgcaatcatt atgagcgagt tgagaaataa acgactcgtt aaagtttatc aaacgatgtc
    13561 cttactacct tattttctat cttgggtcat tatcagttac tttgtttacg cttttttaag
    13621 tcctgacaaa ggaatattca atcagtggat cactggacat ggaggagaag ctgtcaattg
    13681 gtataatgaa ccgaaatatt ggccgtttat cttggtgttc attggtacat ggaaagggat
    13741 tggttataac agcattattt actttgcatc tgttatggga atcgatccga cttattatga
    13801 agctgctatg gttgatggag ctagcaaatg gcagcagatc aaacatgtga cgataccaca
    13861 acttattcca ctaatgacga ttttaacgat tttagccgta ggaaacattt tccgagctga
    13921 ttttggcctg ttttataaca ttcctaggaa ttccggtgca ttatatgatg tgactcaagt
    13981 tttggatacg tatatctaca atggcctgac atccacagga gattttggta tgacggctgc
    14041 tgcaggactt taccaatcag ttgtcggctt tgtcttgttg atgatcacaa atacgatcgc
    14101 ccgacgtttt gatagcgatt ctgcattatt ctaaggagga aaaaaatgaa aaaaaagaaa
    14161 gtggagagag tccaagtccg ctctttcaat aagacggcta attttttctc taatataatg
    14221 attgcactct ttgctatttc ctgtattttg ccatttatat ttgttatcgc catctctttt
    14281 accgatgagt ccatattgtc gactcacggg tacagttttt ggccagaaaa gttcagtata
    14341 tttggttata cgtacttgtt cgaccagatg caggataaaa ttttccaagc gcttttcgtc
    14401 actgtacttg ttactgtttt aggtacactg atcaatagca cggctacttc tttatatgct
    14461 tatgcgattt cacggtcaaa ctttccattc cgtcgttttt ttaccgtttt ttgtttgatt
    14521 acgatgttgt tctcaccagg gatggtggcc aattatcttg ttatgacaaa tcttcttcag
    14581 ttaaaagata cgatttgggc attgatcttg ccaatggctg tcagtccctt caatattatt
    14641 gtgatgcgca cattctttaa acgttcggtc tctgattcga ttattgaatc ggcacggatc
    14701 gatggagcta gcgaactgcg aatatttgtt cagatcgttt taccgttagc tgttccaggt
    14761 attgcgacaa tcagtttatt tgccgcattg ggttactgga atgactggtt caatgcttta
    14821 ctatacatcc aagatgataa gctagttcca ctacagtatc ttttgatgaa aatccaaagt
    14881 aatattcaat atctgacaca aaattcagga gcaggaagcc aattgacagg cggattagcc
    14941 tcagttccag gagaatctgc cagaatggcg atcgtagtca tctcgacgtt gcctattgcg
    15001 atcagctatc catttttcca gaagcatttt gtcaaaggtc taacaatcgg cggagtaaaa
    15061 gaataaagaa acaaaaatat aaatcataaa attaggagga agaaaaatga agttatggaa
    15121 gaaactagcc tttacaggtg tttcagcgtt gttgttggga acattagcag catgcggagg
    15181 ttctggttct aaagaccagg cagaagctag caattcggac actttgcaga tgtatcaaat
    15241 cggagataaa ccagataatt tcgatcaatt gatggaagta gcaaacaaac gaatcgaaaa
    15301 agagatcggt gtaaaagtca atatcaatta cattggctgg ggcgattacg aaaagaaaat
    15361 gaacgtcatc atttcttccg gggaaaatta tgatatcgcc tttgcgaaca actatgtttc
    15421 caatgcccaa aaaggagcct ttgctgattt gactgaatta gcgcctaagt acgctgaaaa
    15481 agcttataat gatttagatg aagcatatat taaaggaaat ctggtcaatg gaaaattata
    15541 tgctttccca gtcaatggaa atgtctttgc tcaacaagta cttactttta acaaagcttt
    15601 actagataaa tacgatcttt caattgatgg aatccaatct tacgctgatg cagaaaaagt
    15661 cttgaaggaa ttccatgaaa aagaaccaaa cacggcagct tttgccattg gacaaggctt
    15721 caaagtccaa gggaactttg attatccttt agggaatacg ttaccatttg ctattgatct
    15781 ggatggagat gattcgaaaa tcatcaacca atacgataat gaaacgtata tcggactgtt
    15841 acgtacaatg catagctggt acaaacaagg actcattcca agtgacgctg caacgagcaa
    15901 taaggattat ccactagaag gaaatacttg gctaatgcgt ggagaaacac aaggaccgta
    15961 tgattatggc gatacaattt tgacaaatgc agcaaaacaa gaacttgtct caaaagcaat
    16021 tactgttcca ctaaaatcta cagctcaagc acaaatggca aattttgtcg tatcaaatac
    16081 ttcaaaaaat aaagaaaaat cagtagaact tctagggctg cttaacagtg atccagaatt
    16141 attgaatggg cttgtttggg ggatcgaggg agaagcatgg gaaaaagtcg atggttcaga
    16201 tgataaaatc aaattgctag atggttatca gccaaataca catatgtctg cttggaatac
    16261 aggaaacaac aagattctat atacacaaga gtctattacg gatgacatga ttgccaaacg
    16321 tgatcaatcg attgctgatg cagaaacttc accgatttta ggattcagct tcaacactga
    16381 cagtgtcaaa acagaattaa gtaatatttc taatgtcatg aatcaatatt tagatggatt
    16441 gaatacaggg actgttgatc cagatgaaac attaccgaaa ttgaaagacg ctttggacaa
    16501 ggctggctat gataaggtat tgaaagaaat gcaaaaacaa tatgatgagt tccgacaaga
    16561 ataataatga ataaagacaa aggggttgtg acaaaagacg tgtcacaacc tcttgttccg
    16621 aataaacggt gttcaaaagc cagtttctcg gtattaagct aaatatatgt aaaaatgtgg
    16681 aaagccatat tcacaaaatt tttcttacta ctcgaaacta agcggctatt tcacaaactc
    16741 ttggtaaacg gtgttcaatc agctgaccct cggtattcgc tcacaaaacg acaaaatatg
    16801 aggaactatt tttccgtttg tttctctaat aatcaggtca aggtgctgat tgcccaacct
    16861 ttttttgtat aatgagaaag tataaactta atgtttggag gagaagatat gttagggaag
    16921 gttttggaag agttatttat ccggatctgg gtcattataa aactaacctt gtatttctgg
    16981 atatatacat ttgccggcgg gatcatcttt ggattaggtg cggcatggaa aacagtcaat
    17041 gaactatttt atttgtacgg attcgagtat aaagaaatca caataaaaag aggctggaat
    17101 atatataaaa gaaatttttt aagaggcaat ctgctattta gtttattttt atctggtact
    17161 gctttattga gttacaattt atatttatct gttcaaatca aagggctcat ttttttagct
    17221 attgatttta ttttactttt tgccttgctc tgcctatttg ctacttatca atacagtatg
    17281 attttagata gtgaatatac gatctctgtt cctaatctgc taaagctaag ttttatttcg
    17341 gttttttcca gcttttcgtc ttttctaaaa ataattattg gtagcggtat aattttaggc
    17401 gtgacttggc aattcaaagg attgatcctg tttggtgtca ttggtctttt gacggtttgg
    17461 aatggtacga tgacaacaca ttggcgtgaa gaattagata aacagttgga aagttatgaa
    17521 taagtttcgg attctatttt caaaaggaac cttactaaat cgtctgttgc ggaaatacgc
    17581 ggttatcatg atcggtgtaa cgatgactgc taccgttatt tttagtatcc atacttggga
    17641 acaaaatcaa aaacaggcag aaaacatgac aagtgatgcc gttcaaagca caagcagaat
    17701 gctgaatgat aaaacaacct tgagtaggat catcaaaaac cagcttgtag ggaattccga
    17761 aaagatcgaa aatgtgacga cctacttaac aaaacccata gatcagtatc tgatgtatgt
    17821 atacgaacag caaaacagta ccgatgaatt agtttctttc ccaaatcaaa tcaaagatct
    17881 ctacgcaaat tatgaagaac taagtgcgat atatatcgtg ttgaatcaac taccggagta
    17941 ttatgaatct tctagagaaa acaaaggtgg ggaaataaaa aaggggacac caaaattact
    18001 agacgccttt tatatcaagt tgcctatcac acaaggagga gctgagtcag gaagtatttt
    18061 tattggtttt caaaagaaag aactagatat gattttagaa aatctaacgt cattcaatgg
    18121 actctcttta tacatgattt ctggaacgac aaatcgacta tacacattcc atgataataa
    18181 aatagctaaa gaaacgtttg aaagacaaga aatgatcatc acagagagtc tgaagaaaaa
    18241 ttcacaattg ccgattgacg atctggaaaa aaacaatttt gttcaacacc aagaactgtc
    18301 tgatgattat cgtatattag ctgtactaga taaaaaaagt gtaaaaatcg aaacgggaaa
    18361 aaatcttgcc ccgctgatca ttggtatcat tattttagac aatatactgc ttatctttct
    18421 ttataaaaca ttcaaacgat attcacagca agtatctatc gtcatgcagg ccatggatca
    18481 aacagcagca gggaatttag agacgcggat cgacataaca aacacggaat atgaactgaa
    18541 ggaactttca atcggtatca acgaaatgtt ggatagcatc aatcagtttg tagaagacat
    18601 ctacaaatta gaaatcaaac agcaagacgc acatatgcgg gcgcttcaag cacagatcaa
    18661 tccacacttt ttatataata cattagaata tatccgaatg tatgcaatca gcgaaggaag
    18721 tgaagaatta gcagatgttg tgtatgcgtt ttccgctttg cttcgaaaca atacgaatca
    18781 agagaaaacg atcactttaa aagaagaact ggacttttgc gaaaaatatg tctatttgta
    18841 tcaaatgcgt tatcctaatc gagtagccta tcattttatg atcgatcctg atttggaaaa
    18901 gatcgaagta cctaaatttg tgatccagcc attagttgaa aattatttta aacacggtat
    18961 tgattttact cgattcgata atgcgctaag tgtcaaagtc ttgcaggaag gcaaacgggt
    19021 aaggatcatc atcaaagata atggaaaagg gatgactgaa aaacggctaa aacagattga
    19081 agaaaaactg tctcatccta aagtggaact tcacggttct atcggtctgc aaaacgtgaa
    19141 tgaacgttta cgtgccagct tcggcagcag ttattatatg tcgcttgaga ataatgagac
    19201 aggtggactg accgtttcta ttacattcaa ggagggatga gcgtgtatca agtgttattg
    19261 gtagatgatg aatacatgat tttgaatggg ttaaaaaaga taattgattg gcaaagttta
    19321 ggctttcaaa tagtagcaac agcagagaat gccaaagaag gactagctgt acttgaacag
    19381 cgacagattg atttagtagt aacggatgtg acaatgccag aaataaatgg actggaattt
    19441 attgaagcgg ctcaaaaaga acgtcataat tttgaattta tgattttatc aggataccaa
    19501 gaattcgatt atttgaaagg aggtatgcaa ttaggcgccg tgaattattt gatgaaaccc
    19561 gtgaataagt tcgaattggt tgaaagcctc aagaaaatca aaacacggtt agatcagcaa
    19621 aatgaacaaa aaaatcaaca agaaatctat caagaactgt tattcagtca atggttgaat
    19681 gaagaattgg atgaaataag tgaagaagaa ataataggac aaataagtga gaagcagcat
    19741 aggatagtat tgattcaact ggcaagaact catgatactc ttatcaatag atggttgcaa
    19801 gaacggcaac aaatctttta ctatcaacga aattacggag accgtgtatt gatcacgttg
    19861 ttgttggagg cagatgaagt tgatggcttc tgttgttttg ttcaagaaaa ctttcctgat
    19921 caggaatggc tgatcagtat cggggaagag acagattctt tggacaaaat ccctgaaaca
    19981 ttccaacaag cgaaagacaa tctacagttg catcaatttt atggagataa agacgagcat
    20041 gttttttacg cagtacaagc agaaacaaaa gatcaaacca tcgatttttc aagtttcaga
    20101 cgcgtgctgc aaaataaaca attggaagtc gctcaaaaaa tgatcactga tttttttgaa
    20161 cagtttcagt tagcagccat gatgccggaa gatatacgat attccagttt tttactgttt
    20221 atggagattc aacgggaatt gattgatctg gaagatgagg aatatttaca aggaatcgaa
    20281 aaaatccatc aggcaaaaac ggtgcaagaa cttcagcagc tacttctgtc attcatcaaa
    20341 aagcatcaga gacagaaaaa gtacagtgac aatgtggaaa aagtaatcgt aatcctgcac
    20401 cagcattatc aagaaccact tacactcaaa gaagtgtcag aaaacctgca tttaaatgtc
    20461 atgtatctag gacagctgtt caaaaaagaa acgaaaaaaa gtttttcagc ttatttgaac
    20521 catttacgta tggaaaaagc gaaacaactg cttttgcaca gtaatcaaaa catcaatgag
    20581 atagcaagtg agattggcta caacaacacc acgtatttct ctaaattatt caagaaaatc
    20641 gtcggcagat cccctaaaga gtaccgagaa aacagtggag aatcataaaa aaaaaagcca
    20701 atgtaatgaa ataacttata aaaaattgtc tagaaatcta attttgggct gttcttatta
    20761 cttgaggcaa ggcagctttt tcatgacctc tcgataaacg gagttcaaaa gccagtttct
    20821 cggtattaag ccaaatttat gcaaaaatgt ggaaagccat tttcacaaaa tttttcttaa
    20881 tactcgaaac taaacagctt tttcacgacc tctccactaa atggtgttca atcagctgac
    20941 cctcggtatt agctcaaaaa atggcaaaat atgaggaact attttgccat ttgtctctct
    21001 aatactcagg tcagaacgct gatttcacaa cctctcaata aacggtgttc aaaagcttgc
    21061 atctgcggta ataagaccaa ccaaacgaaa aatatgagga tctatttttg cttggctgtt
    21121 cttattactt gatgcaggac agctttttca caacctcttg ttaattatag tttgataagg
    21181 aaaaaggcaa atcttttgct tgatatttct tagggtgagg gatgatccct aattggtaag
    21241 agatcgtgcc gcctttcagc aaatcttgat gggtaaaata taatttcgta tattctctgt
    21301 ccatccgttt gattttatgg ataaattgtt gctgcggccg attaggcgtt gcttcaatcg
    21361 tcaattcctt tccatttgac aaaagcaaaa cagccttgtc aattaatggc ataccgataa
    21421 catattcacc ggttccaggc gtgacaggat aaaatcccag actattgaag atataccaag
    21481 cggccatact tccattgtcc tcatctccag ggtaacccat tggagaatcg tcgaaggtct
    21541 gagtcatcaa ctgtttaagc agtggctgtg ccatttcagg ttgtcctata taactgaaca
    21601 agtaaggata gtgaaaactt ggctggtttg aaatagctaa ttgtccaaat tctatcgcgg
    21661 ccatctcact catttcgtgg atctcaaaac catatcctcc tgggtcaaac gttgggggct
    21721 gattgcacag ctcaatgagt ttttctttat atctctcact gccaccatat tttccgatca
    21781 gtcctgaaaa atcgtgataa acagcaaagc tgctttgcca agcacttcct tctgcataat
    21841 cttgtcccca acgattagct gaaaatggtt ctctgaactt gccatcttta tcttttgaac
    21901 gcataaatcc tgactcatag tcaaagatat tttgatagtt caatgattgc tgctgatatt
    21961 tcttcgtcat ttcctcttct tctagtacct tggcaacttg gctaatacaa aaatcgctat
    22021 aagcatagtc taatgtgtga ttgactgatt cgtggtagtg attaggaaca tagccatatg
    22081 tcaagtaatc ttctgttcct tggcgtccat aatttggatg tttgctttga accgtagcac
    22141 ctttttccat tgccgttaga aattcaggca tcaagtctcg tcggatatct tttacagcag
    22201 catctgcaat gaccgcatcg atcaatgtcc caggcataag tccacgttca tcaggagaca
    22261 gccattttgg caaatagcca ctttctctat agctgttcaa aaaaccttcc agcatttctt
    22321 cgtatttttc tacagcaatc aaagaataaa gaggataaac cgttttatac gtatcccaaa
    22381 acccattatt tgtatagaga acaccaggtt ttatagatcg actagtcgta tcatagtgga
    22441 ttttttgccc actaggatca atttcataaa atgtttgtgg aaataaaaac acccgatata
    22501 aattatgata aaacgtccgc aattgttgtt gatcatggtg tgtgagctgt atacgatcaa
    22561 aataggactg ccattgttct tgactgtgag caaggtaagt ctctttgctt tggttttgtt
    22621 ctagttccag gttataagct gcttgttccg agctgataaa agatgtccca aatcggatag
    22681 tttgtttttt tgtctgttca aaatacaacg ggatcgagtc gctatttttg ttggaaacag
    22741 ctaactcatc aattgttaaa ggatattcaa atctcaatat aaaataaaaa gaaaaatcag
    22801 gatcttctga accagcaaaa tgtgtgattt ttccttccac tgtgtaagga tctataacaa
    22861 agagctgatg gcgtcccgga aaggataaaa gtaaaccgct gtcatttttg ctgtaatcaa
    22921 tagataagat tccgccatac atgctaggta tcaatgtaga acagatgcca taacgtaatt
    22981 gacagatcga cagatgagtc gggcaaaata tactttcttc tgggcggtaa gaactttgag
    23041 catggaaaag ggtgttctcc tgtagttttc cattgatcgg cgtaaacagc atatgactga
    23101 aatcacccat ccaaggactt ggttgatggg taagacggta gccttgaaaa acgcggtcat
    23161 caggatgaaa ccaccagctg ccgttttgat ccgtagtttg cggtgcaaaa taattcatcc
    23221 caaaaggaac gccagtataa ggctggcagt tcccattaga gaaatttggc tgattcgctg
    23281 ttgcatgtct agtatctatt tgaccgatat tcattttatt tctcctttgt tgattgtctt
    23341 ttgatgaatg aaactggaaa tttactatcg gatggtcgat cttttgtctc taaccaagtg
    23401 accaaagcat ctcccgcaag cttacctaac tgttcaaaat cttgtgcgat ggttgtcagt
    23461 ggcgggtcaa caagagctgc tgcttggata tcatcaaatc cgataattga aaaatcttca
    23521 gggatatgat aaccatgctg tctcaagaga ttcatggtct ggatagcgac aacatcgttt
    23581 tcacaaacaa aagcagttac ttcatactta gtgatataag aaagcaattc atctaatgtc
    23641 gcgcttttgt catccagtga agtgtggaaa gtcaaaccag ctttgtccaa tgcttcaagg
    23701 taaccaaggt aacgctgtcg aacggattgt ggatgagtct gcgtaccaaa caaataagcg
    23761 atttttgaat gtccctgttc gatcaaataa gaggcagcaa gcgcaccgcc ttggaaatta
    23821 tcggaaagaa cggtaggaaa aggtaactca tagatttttt tatctaatat gacgacaggg
    23881 aattctttca atgaaagctc aaaaagtaag tcaagatgtt gttctgtatc aagagcataa
    23941 taaatcaatc cgtcaaattc attgattagc tcttttgctg ttttattttg tagaaagtca
    24001 agcgtcgtca tcatgacatc aatctgttta tcttgcatca cagggttcaa tcccttgcta
    24061 aaatcaccaa cagacaaatc agcgacatat ggaagaagaa acagaatccg tcgtgttttt
    24121 gtaggagaag caagaatctg ttccggagaa gcggatttaa cgaaactgcc tttcccgcga
    24181 acgcgataaa taagtcctaa ttgctctaat tcagtcaatg cacgtttgga agtgattctg
    24241 cttactttat aggtacgtga aagttctttt tcagttggta gttggctgtc tacaggtaat
    24301 tcaccagtta aaatagccgt ttgcaaatca ttaaatattg tctggtacaa tggttgagtc
    24361 atataaacac ctcttaatga tatatcatat tcaaataata ccataatgga tgaaaaagta
    24421 aataaaaaga tattttttga aagcgtagac ataattggct gtatgaagta taatctttaa
    24481 agatatatca aatagaaaga aggttttatt agtggtttat aaagatatac caaaatcggt
    24541 gcagaaattt atggaagata tcacacaaaa atgtggggat atccatgcgg actgggcaaa
    24601 gaattttaca gcagcatttg ccaatactct gttgacaaca gtcaaaaagc aaaatgacgg
    24661 aaccaccttt ttattgacgg gagacattcc agcgatgtgg ttaagagact ctactgcaca
    24721 agttcgtcct tatttagtga ttgcaaaaga agatgaggaa ttagctgaca tgatcagcgg
    24781 gttagtcaaa aagcaatttt tttatatcaa tatcgatcca tatgcgaatg ccttcaacga
    24841 agaagctaac ggtgctggcc accaaacaga tcatacaaaa atgaacgatt ggatctggga
    24901 aagaaaatat gaaattgatt ctttatgcta cccaatacag ttggcctatc ttctttacaa
    24961 aaatacagga aaaactgatc aattcaatca atcttttatt gaaggtatca aaaaaatctt
    25021 ggacgtgttc aaaacagagc aagatcatga acactctcct tatacatttg tacgagacac
    25081 gacaagaaaa gaagatacgc tgatcaatga cgggcgaggt gcaaaaacag cttttacagg
    25141 aatgacatgg tctggtttcc gtcctagcga tgatgcttgc cgttatggat atctggtacc
    25201 atccaatatg tttgcggtgg tcgtgttagg ttatgtggaa gaaatttttc aaacgatact
    25261 cgatgataaa gaaattgtac agcaaacaca gaaattgaag aaagagatcc aagaggggat
    25321 tcagaatcac ggacgaacgg ttaatcaaaa agggcaaacg atttatgcat atgaagtaga
    25381 tggaatggga aacgccacag tcatggatga cagtaatgtg cccaatctga tcgccgcacc
    25441 ttacttggga tattgttctg aacaagagga agattatctg caaacaagaa gaacattgtt
    25501 gagtaaagaa aatccatatt tctatgaagg aaagtacgca aaaggaattg gatcctccca
    25561 tacgccagaa aaatacgttt ggccgattgc attagctatg gaaggaatga caacgtcaga
    25621 caaatctgaa aaagagcgga tattgaattt acttgtagca actgacgcag gaacacacct
    25681 tatgcacgaa ggattcgatg tgaacaatcc tgaaaattat acgagagaat ggttttcttg
    25741 ggcaaatatg atgttttgcg aattagtcat ggattacttt gatattagag tagaaaagta
    25801 ggaggtatcg taaatgaaaa agaaagtata tatcatttct catagccact gggatcgtga
    25861 atggtacatg gcttacgaac agcatcacat gcgactgatt gaattgatag acgatctact
    25921 agagctattt gaagttgatc cgtccttcaa cagttttcat ttggatgggc aaacgattat
    25981 tttagatgac tatcttcaag taaggccaga aaaaagacag gcaatccaac aagcaatcaa
    26041 tgaaggaaaa ttgagaattg gaccatttta tatcttgcaa gatgattttc ttatcagctc
    26101 ggaatcgaac gtgagaaata tgctgattgg catggaagaa agccgtaaat ggggaacccc
    26161 tgtcatgtta ggctattttc ccgatacatt tggaaatatg ggacagacgc ctcaattaat
    26221 gaaacaagct ggtatttcag cagcagcgtt tggccgtggt gtaaaaccaa ttggctttga
    26281 taatcaagtt ttggaagcag aaaactattc ttcccaatac tcagagatgt ggtggaaagg
    26341 ccctgatcaa acagcaatct ttggtctgct atttgccaat tggtatagca acgggaatga
    26401 gattccagta gaaaaagaag cagctcttgc cttttggaag caaaaattag cggatgcaga
    26461 acaatatgcc tctacgaacc acttattgat gatgaatggt gttgatcatc aaccggtaca
    26521 aaaagatata tcaaaagcaa tccatctcgc aaatgaactg tttccagatt acgagtttat
    26581 tcattctaat tttactgact atctggaagc agttcaaaaa gatgtgccag aagacttagg
    26641 ctcagtagaa ggagaattga caagtcaaga aacggatggc tggtatactt tagccaatac
    26701 agcatctgct cgggtttact taaaacaatg gaataccaag gtccagcgac agctagaaaa
    26761 tattacagaa ccacttgcga cgatggctta tgaagttagt ggaaactatc cccatgatca
    26821 attagattat gcttggaaga cattaatgca aaatcatcct cacgacagta tttgcggttg
    26881 ttcagtcgat tctgtccatc gggaaatgat acctcgtttt gaaaaagcag atgaagttgg
    26941 aaagtatctt gcacaagatt ccttagaaca gctgaccgca gcaatcgata cgaccggatt
    27001 cccaaaagac agctttccat ttgtcattgt aaatactgca ggaatggata aaactggtga
    27061 agcagaaata accatcgaat tagaaagaaa aagattcgct gaaggaatac ctgaacaact
    27121 atatcaagag ttagaaaatt tgcctaaacg taagtatcat gtagaaacaa aaagtggggc
    27181 cactatacca gctattttat ctgaagaaac tgtccaattt ggttatgatt tgccgaaaga
    27241 ccgtttccgt gtgccatata tggcaagaat gatcaaagtg actttaccat tagaaaacat
    27301 gccagcattt tcttgggaaa cattcgcgct tgtagaaggg gaagcgaaag cagaagaaaa
    27361 ggaaacaatg attcatcaga gtggacgaat catcgaaaac ggccctctac atttgacgat
    27421 tgaaaaaaat ggtaccatta caatggaaga tcgcaaaaac aaacgaaagt tgaataatct
    27481 gcatattttt gaagatatcg gcgatatagg aaatgagtat atctttaaac aacctttctg
    27541 tgatcagcca atcctatcca gtaacaaaga aaactctgaa gtaaaagtat tagtagatac
    27601 accggaaata gcaaaaataa gtattctaca ggaaatggaa atccctgttt ctgcagacga
    27661 gcgtttagaa aaagaacagc agatggttgt ggaatttcgt tatcgaaaag cagaacgatc
    27721 caaagaaaaa cgaatccttc aaataaaaac aatcatgaca atcagaaaag atagtaaaaa
    27781 aatcgacttt gaaacgactc tcgacaatca gatgaaagat catcgcttac gtgtcttgtt
    27841 tcctacaaag ttacatgtgg aacatcacga agcagatagt atttttgaag tggtgaagcg
    27901 cccaaaccat gtgtctaaaa gttgggaaaa ccccacgaat ccgcaacatc agcaagcatt
    27961 tgtcaatatt catgatgaag agtacggtgt aacagtcgga aactttggtt tgaatgaata
    28021 tgaagtaaca gaagacggac aaatcgcagt gacgctactt cgcagtgtgg gagaactagg
    28081 cgattgggga tattttccaa caccagaagc acagtgtcta ggtgagcatc ggttcaatta
    28141 cagcattgaa ctacatggac cagaagaaaa attctctact tatttgcatg catacgcagc
    28201 acagattcct ttttccactc aacaaatcaa acatcatgaa ggaacattga tttcaaaaca
    28261 acaatattta acgataaaaa gtgaaacgtt tgcaattaca gctttgaaac gcagcaagtt
    28321 tagtgataaa gtagtagtaa gaggtttcaa tatgtctagt catttagaaa aattggaaat
    28381 aactaaagac aatggaaaaa ctgtcatatt gaatctgctt gaagaaccaa cgaagcaagc
    28441 ggttgtccca ataatccaac cttatgagat tcggacaatc ggattcgagg aggaaaacga
    28501 atgtatggcg gaatagaagc aggcggaaca aaatttgtgt gtgcggtttc agatggtgga
    28561 gaaattttag aaaaattaag tatccctacc acaacaccag aagaaacatt ggatcaggta
    28621 tttgaatttt ttgatcgtta tgaattgaag ggaatcggga ttggctcatt cggcccgatt
    28681 ggtatcgaca aaacaaaaga taattacgga tacgttttgg caactcccaa aaaagggtgg
    28741 gcacaattcg attttcttgg cacaatcaag gaacgctaca atattcctgc tgcttggaca
    28801 acggatgtca atgctgctgc atatggggaa ttgaagcaag gagcagcaca aggaaaaaat
    28861 agttgtattt accttaccgt gggaacagga atcggtgcag gtgtcgtgat caatgaagaa
    28921 attttttcag ggatcgcaca tcctgaaatg ggacatattt gggtgaaacg ccatccagat
    28981 gaccattatg aaggtacttg tccttatcat aaagattgtt tagaaggatt agcagcagga
    29041 ccgtctattg aggcacgcac agggatcaaa gggcaagatc tgccgcaaga tcatcctgtt
    29101 tgggctattc aggcttatta tattgctcaa gcactgatca actatacgtt gacgttagca
    29161 cctgaaaaga ttattttagg cggtggggta atgaatcagg atcatctcct tcaaaaaatc
    29221 cgtcagcaat ttgttgaatt gatgggtggt tatatggaaa cacctcaagt aagtgaatat
    29281 atcgttcgtt ggggactgcc gaatgaaagt gggattatcg gtagtttgct gttagcagaa
    29341 cacgaacatc aaaagtaagc agacaaatta cacaaaaaga acagagtctt atcattatct
    29401 gctgataaga ctctgttctt ttttatttct attcccataa tccaggtaaa gctttaccga
    29461 ctattttttc ttgagtaaat ggatggatca tgtgcagttc taatgcatgg agcatcagtc
    29521 gttcagctgt tctattttgg tagagagggt ctccaacgat cggatgtccc ttatgagcta
    29581 aatgaactct gatctggtgt gtacgtccgg tttccaaaac acaatagact tgtgtttgtt
    29641 cagaaagtac tttgttgaca gtgacatgtg tcaaggcgct ctgaccattt ttatcatcta
    29701 cgaccctttt tctccgatca tggcgatctc gtccaatttt attggtgatg gtcatatctt
    29761 tggcaatttc tccccatacg atggcttgat atctccgata gatcattttt tgttccaaca
    29821 ttcttccaag tatcggcaag acaaatggat tttttgcaaa taaaacggca ccgcttgttt
    29881 ctttgtccaa gcggtggaca acgtaaggtc gttgctgttt agtgtcgaga taagcagcta
    29941 aatgattgag taaggtactg ttttctgtcg gttcatttgg atgagtcttc attcctgcag
    30001 gcttatccac tataatcaaa tgctcatctt catataaaac acggatgtgc ttcgcatctc
    30061 ctaattgaac ttcttgataa ttataatctg tttcttcgaa taacaatgtg atctggtcat
    30121 tgccctttac ttcatgatgg aacaaagcag gttgttgatt gatccaaacg tttttacgta
    30181 tacgcaaaaa gtgtcgaacc tttctaggaa ctaaccattc cttttcaagc aagtcgcgaa
    30241 ttgttgtttc aggatggttc ataggtaaag tgatcgtgat tttcacaagt gtactccttt
    30301 cagtgcaatt gcagactaat tgtaccattt ttaaaacata tttaagaaaa aacttacatt
    30361 tttctgttca ttcttatgtt actctacttg cactaacgta aaaaaacata ttgaactaca
    30421 acttaagcag gaagaaaaca ctctttcact atggtaaaat aagacgattg aatcaaatag
    30481 acaggagaag aagcaaatgg attttcaaag cattttagaa aagataaaag ctgctttgat
    30541 cagtttttgg cgttggatca gaccatatct cggacaattc catcgatggc gaaagcgcat
    30601 ctggaaaaaa tatcatgtga acaaattgat tttgctgatt ggtttgatct gtgtcttagt
    30661 gacaagtatc tacctcttta ttttagcaaa acaagcaaat gtcgaaacgt taaaatcagg
    30721 attaagccaa tcgacagtca tttatgataa gaaaaacgaa gaagctggca cactgtacgc
    30781 ccaaaaagga acatatgtag aattaaacgc gatttctccc tatatccaag atgcagtaat
    30841 ctcgacagaa gataggaatt tttacgagca tcacgggttt gatatcaaag ggattgcccg
    30901 tgcagcagtc cgaatggtct tgtctggcgg aacatcaggg ggcggaggaa gtacgatcac
    30961 tcagcagctt gccaaaaatg cgtatctgac attagaccaa acgtttgatc gaaaagcgaa
    31021 ggaattattt ttggcaatcg agatcgaaaa gaagtacagc aaagaagaaa tcttgaccat
    31081 gtatcttaac aatgcctatt ttggcaacgg ggtatggggt gtccaagacg cttccagaaa
    31141 gtattttgga gtagatgcaa cgaatgttac gctgtctgag gctgctactt tggcaggaat
    31201 gctgaaaggt cctggtattt ataatccgat cgatcaccca aaaaatgcga atgatcggaa
    31261 aaacacagta ctaagtgtaa tggaagaaaa cggaaaaatc acaaaagaac aagaacaagc
    31321 agaaagccag acagatatca gcgcgtatct taatgacaca tacgataatt cagattctgg
    31381 ttatcgttat ccttattatt ttgatgcagt gatcgatgaa gcagttaacg agtatggtct
    31441 tgatgaagaa gatgtcatga ataaaggcta taaaatctat acagctttag atcaggatta
    31501 tcaaaagcaa ttagaagcta cttatcaaaa cagtgcatta ttcccagcaa atgcttcaga
    31561 tggtgccatg gtccaatctg cttcagtagc tttagatccg aatacaggtg gtgtacaagc
    31621 actagtagga cgaagaggag atcatgtctt tagaggattc agctttgcta cacagatgcg
    31681 tcgttcacca ggatcaacga tcaaaccatt aagcgtatat acaccagcac tggaagctgg
    31741 atacaagcct tccagtatct tgaaagacga accgcaaagt tattacgatg cgcataattt
    31801 tgacgggaca taccaaggag aagtaccgat gtatcaagct gttgcacaaa gtttgaattt
    31861 gcctgctgta tggcttttgc atgagatcgg tttacaaaaa ggatatgata aagcagaaga
    31921 attcggcctg cctttagcaa aatctgataa gtattatggc ttagcccttg gtggactgga
    31981 aaaaggagta tctccattga tcatggcggg tgcttacagt gcatttgcca atgatggtca
    32041 gatgtatacg ccgcatctta tcacgaaaat cgttgattcg actggagcgg tgatcgtcga
    32101 taacacaaac aaaaaaccaa aacaggtcat atcaaaggaa acagccgatg aaatgaccag
    32161 catgcttctt ggtacatttt caaatggaac agcggctgct gcgaatcctg caggttatac
    32221 gatagcaggg aaaacaggaa ccacagaaac taatttcgat gccacaaaag caaatgacca
    32281 atggatgatc ggttacacgc cagacgtagt gatttcgaca tggatgggtt acgaagaatc
    32341 cagcaagctg cactatttgg aagggacaag tggaaatgtt gtcgggaaag tcttcaaatc
    32401 agcggcagaa ggcatccttc cgtatacttc aaaaacagga tttagtgtag cagatgccta
    32461 tgccacagga ggacaagtgg tagctgcaga tcaagttgga aacacaggaa attctaatgg
    32521 agagtctgga aattggcaag ataacttgaa tcaatatggt gaacaagcaa aagaagggct
    32581 gaaaaacttc ggcgatatgg tgaaagaagg cgttcaggga attggtgaag cggctaaaga
    32641 cctctggcgg aaatatcaag gagagtagcc cctttgaaaa cgaataaccc catgttacaa
    32701 tagagagtaa ctactaaaag aaaagagggc ataacatgtc aaacatctac gatagcgcga
    32761 atcaaatcga acgtgagatc cgtgaattac cagaattcaa agcgttgaaa gaagcgtacg
    32821 agaaagtaca agcaaacgaa gaagcacaca aactgttcaa agacttccaa gcgatgcaaa
    32881 tcgaattaca agaaaaacaa atgagtggac aagagttcag cgacgaagat gcaatgaaag
    32941 cacaagaaat ggctgtgaaa atccaatcag aagaagtaat caatgacttg atgcaaaaag
    33001 agcaaggctt cagtacaatc atcaatgact tgaaccgtat catcatgaca ccagttcgcg
    33061 acctttacag cgaataaaac tattttatga aacaacagag ggtgtgaaag agacgttcgg
    33121 ccttgagcga tgacaaaatt gcttcttatt gccgataggc tgtctcttga acaccattta
    33181 ccaagaggtc gtgagcctac cgtttaactc tgagttacaa ggaacaattt caaaaaacag
    33241 cttctcatgt ttgatgacta ttgtgacttg tgaccgagga gttggcagga gaacaccgtt
    33301 tattcagaaa taggagctac gacaaaagtc ttgtcatagc tcctattttt tgtcattcat
    33361 ttttcaagcg gtagaaatag cctttttgag ctaacagttt ttcgtaagta cctatttcaa
    33421 cgatttttcc ttcatcgatc acaacgattt tatctgcctc tttgatcgtt gaaagccgat
    33481 gagccacaat aaaagtagtg ggtgtttctg tcaggtaatt cagggcttgc tggatttttt
    33541 tctctgactg gttatctaaa gctgaggttg cttcatctag caaaatgatt tttggctgac
    33601 gtatcaacgc tcgtgcaatg gagatacatt gcttttggcc accagacagc ttgttgccat
    33661 gttcgcctac taaggtatcc agaccatcag gaagctggtc aatcagtgaa gaaagttgcg
    33721 cagcttcgat gacttcatct aaacgttctt ttgatacgtt tttcaagcca taagtgatgt
    33781 tctctttgat cgaagcggag aacaacaaag tggtttgagg aacaacggct aaataatttc
    33841 gcacacttcg catatccagt tcatccaaag gctgatcatc tagaaaaatt tttcctgaag
    33901 tcggctggat aaatccaatc aataagttaa ggagtgtaga ttttccagag ccagatggcc
    33961 caacaaaagc aattgtttct ccagctttca cctctagaga aaaatgatcg ataatcggtt
    34021 tgagtgagtc cggataaaga aaagaaacat cctcaaaacg aaaatttcca tccaaatgtt
    34081 ggattttttt cttaccgtga taagtttcta catcgccagc aatcaacagt tcgccaatag
    34141 aagtgataga ttccatgcct tttgaaatcg taggaatcag cgtgatcatt ccagaaacgg
    34201 aattgacgat cgtcgtgaaa tacgtctgat acatcacgac atcgccgggt tggatgcgcc
    34261 cttgtaaagc taatatccca gtgaaactca aacaaatcag ctgaaatatc tgaaaactag
    34321 cccagctgac tgatccgaaa acagattgca ggatatctaa gtggaatcct ttttcataga
    34381 tttgagtaaa atgcttattt aagcgagttg tttcgtgttt ttctaaccca tgagctcgag
    34441 caatcggtgc taattcgatc acttcgatca cttttgcaga agtctcttcc atttcttgcc
    34501 tgaagtctga gttggactgt ctgatccttt tacggaaaaa gagagtaacg aatgcggcga
    34561 gaggaacagt caataagaaa aacatgaaaa caacaggact tttataaagc gtgataccta
    34621 aagctacgaa taaattgaca gcgatattta atccgctgac aaatacttga gaggacaacg
    34681 tttggatagc ttctacatca cggatgatct ttgactggat tcgtccagat tgcaattctt
    34741 tttgataagg aatagatagt tcttggattt tcttgataag ggtcgctctt agtccagctt
    34801 ctacttgacg gatcgaagtg ctatggtatt ttacatgaaa ataattcgtc aatatatttt
    34861 gaccaatcag acaagccatc aaaaaagcgt tgaaataaat ggcctgcaac tgagaagaat
    34921 ctttcgatga agctgcattg attacattgg caatagcgat cggcattaac caagatggaa
    34981 gatgtttgat aataaaaaag agtcctgaca tggcaaaacg ccaataattt ccctgataaa
    35041 gatgcagcaa tgtctgaaaa gcatttgcat gatatttttg ataacttttc tgtattcgtt
    35101 cctccataat cttctcctta acaatcttgg taaataaact gcaagtgttc tattgcttca
    35161 ggaacataaa tctcaggagt agcttcaaga gtggcgtaca ttagaggacg ctcatatttg
    35221 atataatgca gtaccgggcg gaaatctaaa cagcccttgc caacaggtac catgcggatc
    35281 tttccatttt ccatgatata gtctttgaga tgaagcgctg taatataacc atgtaaattg
    35341 tccaaggcac ctcggatcac tttttcctga tcagcatgat tttctttatg catcaaattc
    35401 gcacaatcta aaatgatttt taaatttggt gaagctactt catcgattaa acgtttagct
    35461 aactgatagt tatagattgg atgattgatc cctgcttcaa cagcaacagt tacgccaaaa
    35521 ttttctgcat gagcgactaa ttcaatgata gaatttctgg cgatctgata agcttcttca
    35581 gtaaaatttt cttttgtgta accgacagag acactaccgg tttccgtagc aatcatcttg
    35641 gcttgatagg cagagcacag agcaatttgc tgtttgaaag ttgccaatgc ttgtgcacga
    35701 acttcttgat ttttgctgga taggttgata tagcatccta aaatggaaag ttcgatattg
    35761 tttttttgga agtattcacc aaaataggca gcactcccaa gtgtcatgtc agttaattta
    35821 agttgttcag gaaatgcttt ttgtggtgca aattggatat gggacaagtg aagctgtgat
    35881 actttttgaa cgatttcttc acgatttcga acatctaaat cgtgggcacg gatgcctaaa
    35941 tttaatggaa acatctcaaa ctcctttttg taaataatta gcaagaggca gacgggattc
    36001 ttttatcaat tcaacaatta ttcgggcaac tttatcagcg ccttctggac taaagtgggt
    36061 attgtctttt agtccttctg ggtaattttt acaagtatca ggcataagat gcaggtagaa
    36121 tttttttgtc tcttcttttg agaaggtctg gaacaattct tgtgatcttg agaacacatc
    36181 taaaagagga atatggtgtt tctcagcaaa tgcacgcatc gcttttggat agtctccaag
    36241 tatatctgga ttcaatgttc cgttttctaa gtaatctcgt cgcgtcacag atgtcagtaa
    36301 gaccatttgg acgttcgctt tttttgcgca ttcaaaaaat atctgcagat tttttaaata
    36361 gctaccgaag ggaagcgtac ctctttcttc ttggattttc tggtcgttat gtccaaattg
    36421 tacaaataag aaatcattcg gctgaaactg tgaagctaga cgggctaacc ttccttcctg
    36481 gataaatgat ttggtgctgc gtccattctt tgcttggtta ttgatctgga tctcgggtga
    36541 aaaataagca gagatttttt ctccccaacc tgtctcggga cgcttgtttt catctttttc
    36601 tgccgcagta gaatcaccgg caatatggat agtaggcatg ttatctcttc tttcataaag
    36661 gtttataggc aatgaagcag aacagcaaga gaagaagacg gagcaa
//
LOCUS       DAXLPC010000017        36552 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.017, whole genome shotgun sequence.
ACCESSION   DAXLPC010000017 DAXLPC010000000
VERSION     DAXLPC010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36552
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.017"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            25..696
                     /locus_tag="ACF3UE_000825"
     CDS             25..696
                     /locus_tag="ACF3UE_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD3634280.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            755..1195
                     /locus_tag="ACF3UE_000826"
     CDS             755..1195
                     /locus_tag="ACF3UE_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634281.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1207..1875
                     /locus_tag="ACF3UE_000827"
     CDS             1207..1875
                     /locus_tag="ACF3UE_000827"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFD3634282.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1939..2562
                     /locus_tag="ACF3UE_000828"
     CDS             1939..2562
                     /locus_tag="ACF3UE_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFD3634283.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2618..3004
                     /locus_tag="ACF3UE_000829"
     CDS             2618..3004
                     /locus_tag="ACF3UE_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFD3634284.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3217..4608
                     /locus_tag="ACF3UE_000830"
     CDS             3217..4608
                     /locus_tag="ACF3UE_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFD3634285.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            5219..5587
                     /locus_tag="ACF3UE_000831"
     CDS             5219..5587
                     /locus_tag="ACF3UE_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFD3634286.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5767..6708
                     /locus_tag="ACF3UE_000832"
     CDS             5767..6708
                     /locus_tag="ACF3UE_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFD3634287.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6777..7508
                     /locus_tag="ACF3UE_000833"
     CDS             6777..7508
                     /locus_tag="ACF3UE_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFD3634288.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7652..9832
                     /locus_tag="ACF3UE_000834"
     CDS             7652..9832
                     /locus_tag="ACF3UE_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFD3634289.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9852..10334
                     /locus_tag="ACF3UE_000835"
     CDS             9852..10334
                     /locus_tag="ACF3UE_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFD3634290.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            10350..11111
                     /locus_tag="ACF3UE_000836"
     CDS             10350..11111
                     /locus_tag="ACF3UE_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFD3634291.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            11242..12576
                     /gene="murC"
                     /locus_tag="ACF3UE_000837"
     CDS             11242..12576
                     /gene="murC"
                     /locus_tag="ACF3UE_000837"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFD3634292.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12883..13368
                     /locus_tag="ACF3UE_000838"
     CDS             12883..13368
                     /locus_tag="ACF3UE_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFD3634293.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            13361..14044
                     /locus_tag="ACF3UE_000839"
     CDS             13361..14044
                     /locus_tag="ACF3UE_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFD3634294.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            14170..16815
                     /gene="polA"
                     /locus_tag="ACF3UE_000840"
     CDS             14170..16815
                     /gene="polA"
                     /locus_tag="ACF3UE_000840"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFD3634295.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16860..17696
                     /gene="mutM"
                     /locus_tag="ACF3UE_000841"
     CDS             16860..17696
                     /gene="mutM"
                     /locus_tag="ACF3UE_000841"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFD3634296.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17660..18289
                     /gene="coaE"
                     /locus_tag="ACF3UE_000842"
     CDS             17660..18289
                     /gene="coaE"
                     /locus_tag="ACF3UE_000842"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFD3634297.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            18341..18673
                     /locus_tag="ACF3UE_000843"
     CDS             18341..18673
                     /locus_tag="ACF3UE_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFD3634298.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18985..19476
                     /gene="nrdR"
                     /locus_tag="ACF3UE_000844"
     CDS             18985..19476
                     /gene="nrdR"
                     /locus_tag="ACF3UE_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFD3634299.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19499..20872
                     /locus_tag="ACF3UE_000845"
     CDS             19499..20872
                     /locus_tag="ACF3UE_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFD3634300.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20872..21798
                     /gene="dnaI"
                     /locus_tag="ACF3UE_000846"
     CDS             20872..21798
                     /gene="dnaI"
                     /locus_tag="ACF3UE_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFD3634301.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21927..22367
                     /locus_tag="ACF3UE_000847"
     CDS             21927..22367
                     /locus_tag="ACF3UE_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFD3634302.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            22511..23212
                     /locus_tag="ACF3UE_000848"
     CDS             22511..23212
                     /locus_tag="ACF3UE_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFD3634303.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            23209..24330
                     /locus_tag="ACF3UE_000849"
     CDS             23209..24330
                     /locus_tag="ACF3UE_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFD3634304.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            24345..25577
                     /gene="pepT"
                     /locus_tag="ACF3UE_000850"
     CDS             24345..25577
                     /gene="pepT"
                     /locus_tag="ACF3UE_000850"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFD3634305.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            25709..26617
                     /locus_tag="ACF3UE_000851"
     CDS             25709..26617
                     /locus_tag="ACF3UE_000851"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD3634306.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            26652..26924
                     /locus_tag="ACF3UE_000852"
     CDS             26652..26924
                     /locus_tag="ACF3UE_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFD3634307.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            26935..27981
                     /locus_tag="ACF3UE_000853"
     CDS             26935..27981
                     /locus_tag="ACF3UE_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFD3634308.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            28232..30841
                     /gene="clpB"
                     /locus_tag="ACF3UE_000854"
     CDS             28232..30841
                     /gene="clpB"
                     /locus_tag="ACF3UE_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFD3634309.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(30992..31678)
                     /locus_tag="ACF3UE_000855"
     CDS             complement(30992..31678)
                     /locus_tag="ACF3UE_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634310.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(31656..32150)
                     /locus_tag="ACF3UE_000856"
     CDS             complement(31656..32150)
                     /locus_tag="ACF3UE_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFD3634311.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(32170..33390)
                     /locus_tag="ACF3UE_000857"
     CDS             complement(32170..33390)
                     /locus_tag="ACF3UE_000857"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3634312.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            33537..35372
                     /gene="lepA"
                     /locus_tag="ACF3UE_000858"
     CDS             33537..35372
                     /gene="lepA"
                     /locus_tag="ACF3UE_000858"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFD3634313.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(35466..>36552)
                     /locus_tag="ACF3UE_000859"
     CDS             complement(35466..>36552)
                     /locus_tag="ACF3UE_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3634314.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT        12166 a         6465 c         7815 g        10106 t
ORIGIN      
        1 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
       61 gagcgatcta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
      121 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
      181 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
      241 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
      301 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
      361 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
      421 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
      481 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
      541 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
      601 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
      661 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
      721 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
      781 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
      841 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
      901 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
      961 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
     1021 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
     1081 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
     1141 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
     1201 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
     1261 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
     1321 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
     1381 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
     1441 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
     1501 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
     1561 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
     1621 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
     1681 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
     1741 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
     1801 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
     1861 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
     1921 gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac attgtttgat
     1981 acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg tatcagtatg
     2041 gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt gatcaatgaa
     2101 tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa agaaagtacg
     2161 gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa agacaacggc
     2221 ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct gttaaaagaa
     2281 catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt tcctcgtaaa
     2341 cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag aacagacacg
     2401 atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg agtcgctact
     2461 tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt ggtaggaaat
     2521 ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct ttcaaaggag
     2581 atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa gacaaaaaga
     2641 agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag aaacagattt
     2701 gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag aacatagcat
     2761 cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat ctggaagtgt
     2821 gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg tcacacaaga
     2881 agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt cttatgaggt
     2941 gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag aaaaacaaga
     3001 atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt ttttttatta
     3061 ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat aaaagtcact
     3121 gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt tacttccttc
     3181 gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat cacagtttta
     3241 gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa gcgccataca
     3301 aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg cggtctgctt
     3361 caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg gatcgggatt
     3421 gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt gtttatttcg
     3481 atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat tagtgcgact
     3541 gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat tggttcaaca
     3601 atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac agcacgaatc
     3661 tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca gcagatttta
     3721 tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac aagtacgatt
     3781 ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa aagaaaagcg
     3841 ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat cattatgcgg
     3901 atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat gacaaacgtt
     3961 ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt tgcttcttac
     4021 gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc aaaagtcaat
     4081 ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac ttcacgttca
     4141 agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg agtagatgat
     4201 gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg ctgtgctggc
     4261 gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa tgtctttagt
     4321 ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg tgtagctgga
     4381 gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa cttgccagta
     4441 gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg tacagcagta
     4501 aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa agatttagat
     4561 cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc aaaaagaggt
     4621 tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat agtttctcaa
     4681 atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg tgaataagag
     4741 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa tagttcctca
     4801 tattttacgt ttggttgagc ttattaccgc agatgcaagc ttttgaacac cgtttaagaa
     4861 agaggtcgtg agcctgccgt ttcactctga gtcacaaaga gcaatttcaa aaaatagctt
     4921 ctcatgtttg ttgaatattg tgtcttgtga ccgaggagtt gtcaggagaa caccgtttac
     4981 cagaggttgt gacttgtttt tagtcacgac ctcttttttt atttattcca tataaataca
     5041 cattatttat tccgaaaagt gaaagcgcaa ataacaaaaa caaccaactt atttattatt
     5101 aaagaaaagc gtatttaagt aggacgattc tgttgagagc tttcgtagat tttcccattt
     5161 tcctatggta aactgacaaa gttgagaatg ttagaacaga tcgtttagga ggaaacagat
     5221 gtttacgaat gaaataaaaa tcatgcttta tgtggacgat gtagaaaaaa atgcaacgtt
     5281 ttggagagca gttggctttg cggaaaaaga tcgtcaagaa atggatggga cgcttataat
     5341 tgaagtagga gttgaggaca gtcaaacctc atttctgtta tatgatcgag catttgttga
     5401 gtcccattca cctggcacag ctactagtgc cccatctttg atgttttaca gtaaagatat
     5461 ctttggacta tataaaaaaa tgcagacgca atcagtcaca ttaggtgata tggtacagct
     5521 tggagaagaa tatgtcttta actttgctga tcccgatggc aactactttg cggttacagg
     5581 taaataatag aaataaagac tttgtttttc tgtgcgaaac aggaaagcga agtcttttta
     5641 attcaaataa taatattatg taaacaaaaa actttccatg cgtaattata cacaagcaaa
     5701 taaatcgtca aatgcgaacg ccttctttat actgtttagg aacgaaaaga aggaaggaag
     5761 aaatacatgg attatcaagt actgctttat tacaattata caaaaatcga agaaccagag
     5821 gaatttgcca aaaatcattt agccttttgc aaatctttgg atcttaaagg tcgtattcta
     5881 gtagctgaag aaggaataaa tggtactgtg tctggaaccg ttgaaaacac gactgcctat
     5941 atgaaagcaa tgaaagctga tcctcgattt gctgatacga tgttcaagat cgatccaagc
     6001 gaaggacatg cctttaagaa gatgtttgta agataccgtc cagagcttgt aagtttaaag
     6061 ctagaagagg acattgatcc aaaccaagtg acaggtgcct atctttcacc gcaagaattt
     6121 aaagaagcta ttttagatga acagacagtg gtgattgatg cacggaatga ttatgaatat
     6181 gacttgggac attttcgagg ggctgtacgc ccagatatac gcagttttcg agagcttcca
     6241 gactggatcc gcgagcacaa agaagaattt atggaaaaac gggtagtgac ctactgtact
     6301 ggtggcattc gttgcgagaa gttttctggt tggcttgtcc gtgaaggatt caaagatgtc
     6361 ggacagctgc atggcggtat tgctacttat ggtaaggatc ctgaagtcca aggagaatta
     6421 tgggacggca agatgtatgt gtttgatgaa cggatcgctg tcgatatcaa ccaagtagat
     6481 aaacaaatcg tcggtcgcga ctggtttgac ggaacaccat gtgaacgata tatcaattgt
     6541 agcaatcctg agtgcaatcg tcagattctt gcttccattg aaaatgaaga aaaacattta
     6601 ggagcatgta gcatagagtg tgcgaaacat ccgcgcaatc gctatgttca agaccatgga
     6661 atctctccag aagaagcaga actgcggttt acagctttaa ttaaatagaa aacaatagtt
     6721 ttgattgtcg accatttcca atatgcgcta tactagcgtt gaggatggtg atccacatga
     6781 aatcattgat ttatgctatt ggggatgtcc atggcaaaca tgagcttttt gaaaaactta
     6841 ttcactatta tgatccaaag atccatcagc ttgttttatt aggggatctc aatgatcgag
     6901 gtcctcgtac aaaagaatgt tttttattag gaaagcaatt agtcgaagaa acaggagcca
     6961 tttacctccg gggaaaccat gaagaatatt ttttgcaatt tctgcaatca ccggaggact
     7021 ggtatgcgcc ttatatgaga aatggtggaa aagaaacgtt tgaaagcctg attcacccag
     7081 gggcatcgga ggaatactcc ccaactgaaa tctcgatgat gatccaatcg agatattcag
     7141 aactgattaa atttttagtc cagcgcccct tgtattatga atgggaaaat tatctttttg
     7201 tccatgccgg tgtggatttg acaaagaaag actggcgtaa gacaagtcta agagacttta
     7261 tttggataag ggaaccattt catgaaggga aaaacaatac aggtaagaca attgtatttg
     7321 gacatacgat tacaccaatg ctccatggag atatgcagac aacagacctc tggattcagg
     7381 atcataaaat cggaatggac ggtggggctg tattcggagg gtcattgcat ggggttgttt
     7441 ttgacaagga aggtattctt caagatattg aatatcagaa caacgaagga ccttggcatg
     7501 gaatctgact aatggaaaga atgaaggagc tgtgactttg ttgcggctct ttttattttt
     7561 atagagaata ttgtttcttt cagtagttta acccaggata aaaagtatga tagaataaag
     7621 aagcaatttt tagcagaaaa gaggcatttt aatgacggaa aatttgaacc agacgatcat
     7681 tcagcttgta caaaaagaac tttcagacta tcgtcctaag cagttgacta ctgtacttaa
     7741 tttgttaaat gaaggaaaca ctgttccttt tatcgcgcgt taccgaaaag aaatgactgg
     7801 aagtcttgat gaagtccaga ttcgtgaaat cgaagagcgg tatgcctatc ttgaaaactt
     7861 agaaaaacgt aaaactgaag tgattcggct aatcgatgaa caagggaaac tgactcccga
     7921 gttagaagca gaaatcaccc aagccgtgaa aatgcaacaa gtggaagatt tgtatcgtcc
     7981 atacaaacaa aaacgacgga caaaagcaac gattgctaaa gaaaaaggac ttgaaccact
     8041 cgcgaagtgg ctgatgcagc ttacagatgg agaggtgcaa tctgaagcag aaaaatatat
     8101 tgacaaagaa aaagaagtct cttctgccga agaagcgttg cacggtgctc atgagattat
     8161 tgctgaacaa gtcagcgata atgcaaaatt tcggacttgg attcggtctt atacgtataa
     8221 caaaggtatg tatgtcagca atgtcaagga tgagcaagca gatgaaaaag gcgtatatga
     8281 aatgtattat gactttgcag aacccgtcca taaaatggtt tctcatcgaa tattagctac
     8341 taatcgtgga gaaaaagaag atattctgaa agtattcttt caagtagatg aagcagcaat
     8401 tttagcttac ttggatcgcc aaatagtcaa aaatcctgcc tctccttctt cttcattcgt
     8461 cagagaagcc tatcaggata gttataaacg ctttattcag ccagcaatcg agcgagaact
     8521 gcgcaatgaa ttgactgaaa aggcagatga gcaagcaatc gctattttcg gcgaaaacct
     8581 ccgtaatctt ttgttgcaac cgccactaaa aggtaaagtt gtcctgggat ttgatccggc
     8641 ttatcgtact ggatgtaaac tagcagtcgt agatgcgaca gggaaagttt tagcaatcga
     8701 agttatttat cctcataaac ctgcagcgca agcaaaaaga gaagctgctg gaccagcttt
     8761 tatccaatta attaataaat atcaagtaga tatggtagct atcggaaatg gtacagccag
     8821 tcgggaatct gaactttttg tggctgagca gttgaaatcc gccgaccata aaacctatta
     8881 cgctatcgtc aacgaagcag gcgcttctgt ttactccgct agcgaaattg cacgaaaaga
     8941 atttccgcat ctacaagttg aagaaagaag tgctgtttct attgcccgtc gcctgcaaga
     9001 tcctttagct gaattagtca aaatcgatcc taaagctgtc ggagtaggcc agtaccaaca
     9061 tgacgtttct caaaaacgtt tggctgaaca attggatttt gttgtggaaa cagcggttaa
     9121 ccaagtaggt gtggatgtga atacagcaag cccgcagctc ttgcagcata tatcaggatt
     9181 gaataaaaca actgcccaaa acattgtcat ttatcgtgaa gaaaacggag aattcaccgc
     9241 acgaactcaa ttgaaaaaag tgccacgctt aggaccaaaa gcatatgaac aagcaatcgg
     9301 attcttgcga gtccctggtg ggaaaaacat tttggacaac acaggtatcc atcccgaaag
     9361 ttattctatt gcaaaagaaa tattaacttc agtccaactt tcagaaaaag agcttggtac
     9421 agaagaagca gtagaaaaat tgacacgatt atccgtagag aaactggctg aaagcctatc
     9481 agtcggagaa gaaacgttag ccgatatttt agctgggctg acacaacctg gacgagatat
     9541 gcgtgatgag atgccagcgc ccttattacg tacagatgta ttgagtatgg aagacttgaa
     9601 accagggatg gaattgactg gaacggtccg taatgtcatt gacttcggcg catttgttga
     9661 tatcggtgtg aagcaagacg gacttgtcca tatatcgaaa ctcagcaaaa aattcgtcaa
     9721 gcatcctaca gatgtcgtgt cagtaggaga tatcgtaaca gtttggatag aacaagtcga
     9781 tacgaaaaaa ggcagaatca gtttgacgat gctttcccct tatgaagagt aacaatgagg
     9841 agtaacaaaa attgacacaa gaagaactgc agcagttagt agaagagata tcattaaaaa
     9901 gcttccagct tcctttcaag caccaagcaa tgttcaatcc acgcttacgt acaactggcg
     9961 ggcgctatca tttaaacgat catcatttag attttaatgc gaagctattt gaagagtcag
    10021 acgaagagac gattgcagga atcatcaaac atgaactttg ccattatcat cttcatctag
    10081 ctggaagagg gtatcagcat aaagatatgg atttcaagta tcttttgaaa aaaacaggag
    10141 ggttgcgcta tgcaccagcc ttgacgaaga aacagataaa gatggagtat tatcgatgcc
    10201 aagattgttc tgccacgatc tgccgcaaga gaagaatcga tgtacgcaaa tatcgttgtg
    10261 gaagatgtca tggagaaatc aaatggattg agacaaaaag agaagacttt aatgaagcac
    10321 aaaaaatcag atgaaaggat agaaggcctt tggaaaaaag tgagcagagg aatctaaaag
    10381 actggaatca gctattaaat tttttagccg cacctgaaga gggaaatttt gaggaactga
    10441 cggcacctac acttatttta gctggaaact gtcttcctat cttagctgat aaagcagcac
    10501 aaatgtattt aaatggccaa gtagatcaat tgtttttggt cggaggggtg gggcatgcga
    10561 ctagaatcct ttatgagaat tttgaaaagc aaggatttca ttttgaagat ggcatgagtg
    10621 aaagtgaaat ctgtcgtcag tatctaaaag aagtctatga tttgcccgat aaggcttttc
    10681 tgatagaatc gaagtctaca aattctggag agaacgccac tttttcactg gagattcttc
    10741 attccttagg agctgtacca gaaaaaatct tattgatgaa tgatccgaca ctgcaacgca
    10801 ggactcgagc aacttttgag aaagtatggc aaaatgaaca aactattttc gcgaatgctg
    10861 tgccatttgt gccggaaatc cttcactttt ctgaagagat catctttaca gcaaaagaac
    10921 tgaatcatca atggcctaag gaatatttcc atgcgctagt attaggagaa atggaacgtc
    10981 tccatgacga tgagaacggc tatggtccga aaggaaaaga ttttattcct cacattgata
    11041 tatcagagga agtttggtct tcttacacca gaattaaaga gtcaataaaa acggattttt
    11101 ctcgtacttg accattttag caagcgaatc ctcctttcca aataaatttg gttgaaattt
    11161 tcaatcgttt ataagataat gaggagcgtg ttgaatgtaa tagctaaaag aatggacgct
    11221 agataagaga agaggattca aatggaaaat caaaataaat tgtatcattt tgttggtatc
    11281 aaaggttcag gaatgagctc cttggctctt gttttacatg aacaaggtct aaatgtccaa
    11341 ggatcagaca ttgaaaaata tttctttaca caaagagatt tagaaaaagc aaatatcacg
    11401 attctgccat ttaacgcaga taatgtaaaa ccagggatga cgatcattgc aggaaatgca
    11461 tttcctgatt cacatgaaga aatccagcga gcaaaagaat taggtttgga agtgattcgc
    11521 tatcacgact ttattggtca ttttatccaa aattatacga gtatcgctgt aacaggctct
    11581 cacggaaaaa caagtacgac tggactgctc tctcatgtat tgagtggtgt ccgtccaaca
    11641 agttatctaa ttggagatgg aacaggacat ggtgatccgc aagcggaatt cttttcattt
    11701 gaggcctgtg aatatcgccg tcatttcctt gcctattcac cagactatgc aatcatgacc
    11761 aatatcgatt ttgatcatcc ggattattat acaagtatcg acgatgtatt tacagctttc
    11821 caaacaatgg ctggacaagt gaaaaaagct atttttgcgt atggtgacga tgcttattta
    11881 cgcaaattaa aagcaaatgt gccgatttat tattatggtg tcacagaaaa cgatgatatc
    11941 caagcacgaa acatcgaacg cacaacttct ggttctgctt ttgatgtcta tcatggggat
    12001 gaatttgttg ggcacttcac tgtaccagca ttcggtaaac acaatatctt aaatgcttta
    12061 ggtgttattg cagtagctta tttcgaaaaa ctggatctga aagaagttgc agaagaaatg
    12121 ctgactttcc caggagtaaa acgtcgattc agtgaaaaga tcgtagcaga catgaccgta
    12181 gtcgatgatt atgcgcatca ccctgcagag atcaaagcaa cgattgatgg cgcacgccaa
    12241 aaatatccag ataaagaaat aattgcagtt ttccaacccc atacgtttac gcgtacgatt
    12301 gcattgatgg atgaatttgc agaagcactt gatttagctg ataaagttta cttatgcgat
    12361 atttttggtt cggctcggga agaacaagga aacgttaaga ttgaagacct tggagcgaaa
    12421 atcaaaaaag gtggagaagt catcaaagaa aataatgtat ctccattgtt agattatcat
    12481 gatgcagtag taatcttcat gggtgctgga gatgttcaaa aatttgaaca agcgtatgaa
    12541 aaacttttaa gcagcacgac gaaaaatgta ctgtaataca attactgcag tgtccttata
    12601 aaaatagaaa gagggggagt ggcaaaaatc ttgccaagcc cccttttttg caacttatga
    12661 taaacggtgt tcaaaagctt gcatctgcgg taataagccc aatcaaatca aaaacatgag
    12721 aagctgtttt ttcttggctg ttcttattat ttgatgcagg acagcttttt cacgacctct
    12781 gtaaactata ggaatctgtt aaatcaaggg agcagaactt gccttttacg ctacttttgg
    12841 tacaataatg tatgattaaa aataaactgg agggtttcta tcttgaacat aggtaagccg
    12901 agaaaactag gaaaaacaat aaatgaaatc gaggaaggcg actcgttatc cttaacagaa
    12961 tctattgaag ataaccagct tttgctgtat ttgggattga cgaatgatgc aaatcctttg
    13021 tatatccaac atgactttgc acaaaaaaca gaatatcaac agccaatcgt tccatcagtg
    13081 atgctgatgg ggatcatcac aagtgcaatt tcaaagcatc ttcctggacc aggatcacat
    13141 gttgtcaatt tttctgtcaa ttttattgaa ccggttttcc attatgaaac actgactttt
    13201 cagtttgagg tcataaaagt agataagatg aaggatgtgg tgacgatttc tgtagaagcg
    13261 gagaatacga acgaagatcg tgtgttggat gctgtcgtta tggtccaacc gccacaagtt
    13321 cctgaattgg aaatagcaat cgaaagtgaa ggtgaattga atgaataatc caagtacatc
    13381 aatgtcaggt atcaatcgtt tttatgcaaa agtttatgga tttttaggta tgggacttgc
    13441 ccttagtgca gtcacttctt acttggctct ttgggtattt cctttgcaat tagcaacttt
    13501 tatcaataat tttccactag gctttgtggg tctgtggatc gttgaactga ttttagtaat
    13561 ggttctaggc gtaaaagcac aaaagaatcc gagcttagca atcggtggat ttattgccta
    13621 ctctcttttg aatggcataa cattagcggt tactcttgca tactacgata ttggaacagt
    13681 aacgcaagct ttcttgacag ctactttgat gttcatgggg atgtctgttg tcggagtaac
    13741 aacaaaaaga gatcttagcg gggttggaag agcaggacag gcagctttaa tcggagtgat
    13801 cattgcacta gtcttgaaca tcttcatttt gagaagtagc gtagttgagc tgttcatctc
    13861 cctactgtta gtcgtcatct ttgcagggat tacagcttat gataaccaaa gcatccgtaa
    13921 tatctatgtc cagacaaacg gaacagcaca tagtggaatt gctgtattca tggcattgaa
    13981 gctgtatttg gactttatca acttgttctt ggcgtttctg agaatctttg gacggaacaa
    14041 ctaaaaaaaa aaaaaattca tcagttgggg ctataccgaa ttatttggta tggtcccgct
    14101 ttttcttttc gcattccgca ggattctttg ttagaatgaa taagaacttt acagtaagga
    14161 gttaagaaga tgacaaaaaa taaattatta ctcgttgatg ggaacagtgt ggcttttcgc
    14221 gcattctttg cgcttcacaa ttctcttgaa cgtttcaaaa atagaaacgg tcttcataca
    14281 aatgcaatct atgcattcaa tacgatgttt gaaaatgtta tgcaaaaaga gcaaccgact
    14341 catgttctgg ttgcgttcga tgcaggaaaa acgacttttc ggacagaaat gtatgcggag
    14401 tacaaaggtg gaagatccaa aacacctggc gaattcaaag aacaaatgcc atatatacgt
    14461 gatttgttga caggactagg ggtacagtat tacgaattgc ccaattatga agcagatgat
    14521 attatcggta ctttggcaga aaaagtagac aaagatcaat ttgatgtcgt cgtgctttca
    14581 ggtgatcggg atttgactca attagctagt aaagaagtaa aagtggatat cactgtaaaa
    14641 ggtgtcagcg atatcgaaag ctatacacca gaacatgtag cggaaaaata tgatgggttg
    14701 acgccaaaac agattattga catgaaggga ctagccggag atgcctctga caatatcccc
    14761 ggtgtgacta aaatcggtga aaaaacagct atcaagctat tgaaacaata tggctcagtc
    14821 gaaggaattt atgaacatat cgatgaaatg aagcaaagca aaatgaaaga aaatctgata
    14881 aatgacaaag agcaggcttt cttatcgaaa aaattggcga ccatcaatac ttcagcgcct
    14941 gtggatgtct ctatcgactc attgaagtat gaagggaaaa atctcgataa actcgttccg
    15001 ttttataaag aaatggattt caatcagttc ctttctaaat tgaatatcgt agaagaagaa
    15061 gtaaaaatgg atgatatttt gtttgaagtc gttcatgaat tcaaagagga aatgtttact
    15121 acggatatgg cgttgtacgt ggaaatgatg ggcgacaatt atcatacaga ggaaatcgtc
    15181 ggagtagcgt gggggacaga aaagaaaatt tatgtcacga acgatctatc tgtattcgaa
    15241 aaccgagcgt tccattcttg gatcactgat ccgactcggc tgaaaaaagt atatgatgcg
    15301 aaacgaactt atgttgcttt aaaccgctat actggaaaaa cgaaaggaat cgattttgat
    15361 gtcttgctag gtgcatacct tctcgatacg aatgaaaaaa gcacagatat cgaaggaata
    15421 gctgctcatt acggatacaa cgatatccaa tcagatgaag ctgtatacgg caaaggggcg
    15481 aaaaaaggtt taccagaaga agaggaactc ttttttgctc atttagcgcg aaaagtagct
    15541 gcaatcaatg cgttgacacc aaaattgagc caagaactgg cagaaaaaaa ccaagaagat
    15601 cttttccgga aaatggaact gccattgtct atcattttgg cagagatgga aataagcggg
    15661 atcaaagtag atgcgactcg cttacaagaa atgaagggcg agttctctgc tcgcttaaga
    15721 gagatcgaac aaaaaatcta cgaagaagcc ggcgaagaat tcaatttgaa ttcaccaaag
    15781 caattaggag tgatcttatt tgaaaaaatg ggattacccg ttatcaaaaa aacaaaaact
    15841 ggatattcca cagccgtaga tgtactggaa cagcttcgtg aacaagcacc aatcgtagag
    15901 gatatcctca cctatcgtca aattgcaaaa attcaatcta cctatgtcga gggactgctg
    15961 aaagtgatcc aatcagatgg aaaagtgcat acccgttatg tccagacatt gacccaaaca
    16021 ggacgattaa gctctgttga tcctaatttg cagaacatcc cgattcgatt agatgaaggg
    16081 agaaagatac gtcaggcatt tgttcctaga gaaaaagact ggctgattta ttcttctgac
    16141 tattcacaaa tcgagttacg cgtacttgcg catatctcaa atgatgaaca tttgaaagct
    16201 gccttcctag aaggtcaaga tatccatgcc agcacagcga tgcgtgtatt tggaatcgaa
    16261 aaggcagagg atgtcacacc aaatatgcgt aggcaggcaa aagcagtgaa ttttggtatc
    16321 gtgtatggca tctctgatta cggactttca caaaatctag gaatcagccg aaaagcagca
    16381 cagcaataca tcgatacgta ctttgaaaaa tacccaggtg tcaaagaata tatggaaaga
    16441 atcgtacgcg aagcaaaaga ccaaggctac gtcgaaacgc tgtatcaccg ccgtcgatat
    16501 ctgccagaca tcaattcaag aaattacaat atccgttctt ttgcggaacg aacagctatc
    16561 aatacaccaa tccaaggaag tgctgctgat attttgaaaa tcgcgatgat cgaattggat
    16621 aaacgattaa aagaaacagg tcttcaagct acgatgctgt tacaagttca tgatgaactt
    16681 gtcttcgagg taccggaaaa agaacttgaa tcattagata aattggtgaa ggaagttatg
    16741 gaacaagctg tttctcttca tgtaccactg atcactgaca gcagttgggg aaaaacgtgg
    16801 tacgaagcaa aataaacatt gtttaagaca gagcaatata atgaaggtga aaagaaaaaa
    16861 tgccagaatt accagaagta gaaaccgttc gtaaaggatt ggaacggtta gtagtaggaa
    16921 aaacgattca aaaagttcag gtcttgtggc ccaagatcat cgagcaacca gagacaccca
    16981 tctttgaggc ttctcttgtt ggcgaaacca tccaatccat tggacgtaga gggaagtttt
    17041 taatttttca tctcgatcat tgtgaactga tctcacactt gcgaatggaa ggaaaatatc
    17101 aatttacgaa agaaaataca ccaatcgata aacatacgca tgtacttttc ttttttgagg
    17161 atggaagcca acttcgctac aacgatgtac gaaaatttgg tcgtatgaca atcgtcgaaa
    17221 aaggagcaag tgcaacttac cgaggaatca tgaaattggg acctgagcct ttgccagata
    17281 gcttcttatt agcagatttc gcaaatggac tgaaaaagtc ccacaaagca atcaagccat
    17341 tgctgctaga ccaacgtcta gtgactggtc taggtaatat ttatgtagat gaagcattat
    17401 gggaagcgaa gatccatcca gaacaaccgg cgaacacact gcgccccaaa gaggtagaac
    17461 aattacgtct atcgatcatt gatgttttgg atcgtgcaat agaagccgga ggtaccacga
    17521 ttcgcagtta tttgaatgca ttaggagaat caggcggatt tcaagtagca ctgcatgtct
    17581 atcagcaaac tggcaaacca tgtatacgtt gtggaacgcc gatcgtgaaa acaaaagtgg
    17641 cacaaagggg gacgcactat tgtccgaatt gtcaaaggct aaaaatcgca aagtaggatt
    17701 tgttttaggt ttgacgggtg gaatagctac cggtaaaagt acggcagcca aagtctttca
    17761 gtctcatgga tttcctttga tcgatggcga tgtgattgcc agagaaactg ttgagcctgg
    17821 aacgcttgct ctgaggaaaa ttgtatcagt gtttggccaa gaggtattgc agcctgatgg
    17881 gcaactagat cgagggaaac ttgggatgat tgtttttcca tcaaaggaaa aacggcaaaa
    17941 acttgatcag ctattagatc cgtttatccg aaaagcgata aaagatcaaa tcgcctctct
    18001 aagttccaat catcctttag taattgtaga tatcccattg ctctacgaag gtcattatga
    18061 ccactatatg gatgcagtag ctgtcgttta tactacgcca gaaactcagc ttcagcgttt
    18121 gatgaaacgt aatcaactga cgctagaaca agcgcagcag agaattagta gtcaacttcc
    18181 aatcgaagaa aaaaagcagc gtgcggatat tttgttcgac aacaatggaa caaaagaaat
    18241 acttgtggga caaatcgaaa attggctttt tgctaatcgc tttctttgag tatctgtgtc
    18301 aattttgcta tcctgagtat atagaaagtg agggatagcg atgggatcat taaaaaatca
    18361 aaaggataaa gtcgtaggta acgcaaaaga aaaaatcggc gagatgctca ataaagaaaa
    18421 tctaatcgat gaaggtcgta cgcaatcaga aacagcagaa gaaaaagaaa agcagtacca
    18481 agcaagaatc gatgaaatag aagaccagca ggcagaagaa gaagcgaagc ggcaagattt
    18541 gactcaagaa cgaaaaaatc cgacacctga tcgtagtaaa acaccgctcc cagaaagtga
    18601 ccacattccc gatgagcaaa aaatcgagga acagcgaatg aaacactata caggaatcga
    18661 agagaagtta taaaatagta aaaaatcgag atgtgacttg aagcagatga gaaggtgttc
    18721 atctgcttca agttttttgt gctagatgac taaatcagct tttgtgtaag ttatttctca
    18781 gtaatcaagg tgatcagtat tggaaaattg aaatttagta aggacagggg acacaattac
    18841 gcatgaaagt agaaaaaatt gttcttatat ccgtgttttt tgggtaggac agtcgcgttt
    18901 gtgatttgtt tcgtgttata atacaactag ttgtaaagaa agacacatcc tttatataaa
    18961 atgcgatgca agaggtgaga caaaatgaga tgtcccagat gtcaacataa taattcacga
    19021 gtaatcgaca gccgtcaagc agatgatgga cgtgcgatcc gtcgccgtcg cgaatgtgag
    19081 aattgttcgt tccgattcac tacatttgaa cgaattgaag ctgctccgtt attagtaatc
    19141 aagaaaaacg gggaacgcga agagttcaat cgcgataaaa ttttaagagg actcatccgt
    19201 tcagcagaaa aaagacctgt agctatggaa caaatggaac aaatcgtcaa ccatgtcgaa
    19261 aaccgcgtac gcagtctcgg agaaaacgaa gtatcgacga atctaattgg tgaatatgtg
    19321 atggaagatt tagttgattt agacgaaatc gcttatattc gttttgcaag tgtttatcgc
    19381 cagttcaaag atatgtctgt tttcttaaaa gagttgcaag atatcgtgga taaagcaaaa
    19441 gaaaataata aagagaataa taaagaaaac aattaagaaa caaaaaggag gcatttcctt
    19501 ggaaaatgct tggaaagagc ttcaaccaaa aaatatttac caaggaagaa aagcggctcc
    19561 gctgagagaa gacagcaaga acgccttgct gtatctttat cagccactaa tcggcggaga
    19621 agccttgagt atctatttca ccctgttatc agaaatctct caagaatctg gcaaaggtcc
    19681 tgaagggatg catgcagatc tgcttagtag tctaggctgc ggtatcccgc aattttatga
    19741 tgcaagaaaa aagctagaag gaatcggctt actggatgtt tattttaaag aagatagtga
    19801 tctgggacct cgttttattt atgagctgtt agaaccactc attcctaaag catttttcaa
    19861 agactctgtt ctggcttttc ttcttctgga aaaagttggt gaacgacgat tccagaagct
    19921 tacccaattc tttgaaccta aaaggcatac agcagaggga tatcaaaaaa tcacaaaaaa
    19981 atttttagat gtttatcgct tcaatgaagc agtgtacgct gctaatcaag aaaacatcga
    20041 atcgctgaat aaatcttttg aagaatctga atcagtagca ttacttgaag cagattcgac
    20101 attcgattgg cagtttttga atgattggct ggcaaaaaaa catattgcaa gtcttgatga
    20161 tccaatcatc aaacaagtcg acatgtatca tcagctttac ggtttcgatg aattgacact
    20221 tggcgaactg atcagtcaat cttatgactt tagtgaacaa aaagtatctg aaaaagaact
    20281 gcaaaaagcc attttggcaa tgcagagacg tccggtgaag caaacaaaag aaacagttgc
    20341 ggtttctgaa aacagtaatg aaccctcgtc aaacgaacat ttgacaaacg cagcgcttca
    20401 gctgataaaa gaagcacaga gcattccacc gatgaaatat ctggaagcaa tcaagtcaga
    20461 aaaaggcgga tatgtttcta aacaagaaaa ctggttactg caagatcttg tttctcaatc
    20521 aggtctttcc agtagcgtga tcaatgtttt gctgaattat gtactagtga tcaagaataa
    20581 tgctagctta aatgccagtt atgtaaatac agtggcaaat gaatgggcac aaaagaaaat
    20641 cgccacagca gaagaagcga tccagcacat tcggcaaata agtaatcaag caaaacaatc
    20701 aaaacaaaag aagcaaacaa attatcaaac tggcaagcga aatgttcgac gggaaaagct
    20761 tcctgattgg gtcaaccagc caaaagatga aaaacagatc agcagcgaga aaaaagcaga
    20821 gattgaccgc cgttttaaag aatacctggc aaaaaaggag ggtgatatct agtggaagac
    20881 gtaggcaaag aattgaagag gatcatcagc aaacgcaatt atcaagaaaa gtatgctgaa
    20941 atgatcgctg aagtcttaaa tgatgcggat gttcaagctt ttctaagcgc acaccaagaa
    21001 gaattgacac aagcggatat tgaaaaaagt tacgctaaat tgtatgaatt cgtgcaagaa
    21061 aagcgtaaat atcaaaaaaa cgatccaacg atgatcgctc ccggctatga gccgaagctg
    21121 acgttgaatt ttcattatgt ggatgtcact tatgtaccaa cggaagcatt gttagcacgg
    21181 caaagacaag aagaaatcag aagccgagta aaagcaatgg atatgccaaa agatattcaa
    21241 tcggcttctt ttgaaaactt tgaacgtaca gatggacgag gatatgcgag cttagaagcc
    21301 ctagattttg tagagaaata tactgctgat ccaaaagggt atcataaagg actgtatcta
    21361 gtaggaagtt ttggtattgg aaaaacatat ttattaggag caacagcgag agaattagcg
    21421 attgctggat tcaccacgac gctagtccat tttccgacat ttgccgttga gatgaaacag
    21481 gcaatcggaa aagatcaagt ggcagaaaag ttagatgcag tgaaacgttc acctattttg
    21541 atgatcgatg acattggtgc agatgcgatg agtagttgga tacgagacga agtattcggt
    21601 gttatccttc aatatcggat gcaggaacag ttaccaacct tcttctcatc gaattttaca
    21661 atggatgaat tggaacagca tttgtccgtc actcaacgtg gagatgaaga gccgctaaaa
    21721 gcgaaacgga taatggaacg catacgttat ttgacaaaag aaatcgaaat gactggtcgc
    21781 aaccgacgca atggttgaac agttgacaag tccaactgac atttgaccta gtagtaaaag
    21841 caggtcagcg aatcattata tggacagaaa tgaccggaga caatcaccgc aacaagtaat
    21901 gcagaaactt aaacggagga ttttttatga gggctatttt ttctagtata tctgtagttg
    21961 gtctattttt tcttttagca ggctgcggta gcgcagatag caacacaggt tctgttgatt
    22021 cgattgatgc gggtcaaaca gtaaaaacaa gcagtacgaa aacggagaga caaagcatat
    22081 ttgtcggaac gattgaaagt atcactcaag tagaagcaga agaagaaacg cttcagttga
    22141 aactcgtcga tgtcatggcc aaagaagatc cagcgaatat gggaacgtca ttcagcaatg
    22201 acggagtgat cttaaatgct actgctgaaa aaataagcgt ggacataaat gaattgaaaa
    22261 tcggtgacaa agtccaattt acattagttg agatgccgat catgacgatg tctatcccac
    22321 cgcaagttcc tggagattcg attattgatg tttcattgaa caaataacca ataacatttt
    22381 ttcaaaaata agaaaatgtt gttttataga acgaaaaggt atatttttta aggagatatg
    22441 ggaatttttt tattcctagt ctccttattt tatttggaaa atgctataat tatctagaag
    22501 gagtgaagct atgaaccatt tagatttatc tcagcgctta gccgcagtgg gtgactttgt
    22561 ccctgaatcc gctcgtttag cagacattgg atcagatcac gcttacttac ccgttgcatt
    22621 gatattaaga ggaaaaatcg aatatgcagt tgctggtgaa gtcgttcaag gtccttatga
    22681 atcagcacgt aagcaagtca aaaaagatgg attagaagac cgtatcaccg tacgccttgc
    22741 aaatggtcta gatgctatcc agccacaaga tggtattaca gctgtcacga ttgcgggtat
    22801 gggaggttca ctgatccgag atatcctaga agctggcaag ttgaatcaac gcttaagcgg
    22861 acaagaacgt ttgatccttc agccaaacat cggagagcgt acattacgat cttggctgca
    22921 agaaaatcag tataaaatcc aatcagaaaa aatacttgaa gaaaataaaa aaatatatga
    22981 aatcattgta gccgaaaaag aacaaaaacc agttacttac aatgaaatgg agctgatgtt
    23041 cgggccattt ctgcttgaag agaaaagtga gatcttcaaa tcaaaatgga caagagagct
    23101 tcaacaaaga aaagctatcc gtgaacagct caaacaagca gctaatcaag aggcacgtca
    23161 aaaacaaatc gagcaggaaa tccaaatgat tgaggaggtt ttaaagccat gacaatcagc
    23221 ggacgcactt tcatccaaaa gtttgaaagc tattgtcctc agtggctagc tgaagaagga
    23281 gacccagtcg gactgcatat cggaacattg gataagccaa tccaacgagt aatgatgaca
    23341 ttagacgttc gtccagaagt ggtcgaagaa gcaatcaaga aaaaaatcga tttgctgatt
    23401 gctaaacatc ctccaatctt tcgtcctgta aaacggctgg ttactgatca gccacaagaa
    23461 aaaatgtatg cagatttgtt gaaacatgat attgccgtct atgcagcaca cacgaacatg
    23521 gatattattt gggatggact gaatgactgg ttttgtgaac ttctcggtat tgaagtggag
    23581 agttatttag taaagactca tgagattcat tataaaaaac tggccgttta tgtacctgtg
    23641 gatcatgcac agaaaatgcg tgaagtatta gctgcagctg gtgctggtac acaaggtgat
    23701 tataccggta caagttttac ctcgattgga cacggtcgat ttactccgga agctggtgca
    23761 caaccagcga ttgggaaagt agggaagaca gaacaagttc aagaggcaaa agttgaggtt
    23821 attttgccgg aaactatcga aaaacaagtg attcaagcca tgcggtcagc tcatccttat
    23881 gaggaacctg cttatgatct tttcgctata gatgaaccag tcgaaatgtt tgggttagga
    23941 cgagtaggtg aattgccgca agaaatttct atagaggcat ttgtagaaca agtaaaagaa
    24001 gcgttccaac tagatggact gagaatagtc cagccaaaaa atgcaaaatc ctctgtgaag
    24061 cgcattgcga tttgcggtgg aagcggtgaa aaattttatc cgcaagcaat cgcccaaaga
    24121 gcagatgtct atatcacggg agatatctat tatcatacgg ctcatgatat gcaaagcgct
    24181 gggttgattg caattgatcc cggtcattat attgaatcgt tatgcaagca acgatttatc
    24241 gagaaatttg aatcttggaa acaagaagaa aattgggata ttaacttttt cgtttctgaa
    24301 acaaatacaa acccatttca atttaattaa aaggagagaa tactatgtac gaaaatcttt
    24361 tgccacgttt tttacgatat gtcaaaacag aaacacgctc cgatgcaaca agcaaaacga
    24421 ctccatcgac tcagacacaa gttgcttttg cgcaagaatt gaaaaaagaa ttagaagagt
    24481 taggcttagc tgatgttttc tataatgaag ataacggatt cgttatggga acattaccaa
    24541 gcaatgttga tcatgaagtg cgttccattg gatttatttc ccacatggat acagcagatt
    24601 ttaatgcagt aggagtcaat ccacaaatca ttgaaaacta tgatggcgag tctacgatcg
    24661 tactagatgc ggaagaacgc tatacattga atacaaaaga ttttccaaat ttgaaaaatt
    24721 atgaaggcca cacattgatc acaacagatg gcagtacatt actgggagca gatgacaaat
    24781 cagggattgc ggaaatcatg actgcaatgg agatcttgat caataatcct tctatccctc
    24841 acggtaccat caaagtggct tttggtcctg atgaagaaat cggtgtcgga gcggataaat
    24901 tcgatgttga gcaattcgat gtagattttg cttatacagt cgatggtggt cctttaggtg
    24961 agttgcagta tgaaacgttt agtgctgctc aagcaaatat tacgatccaa gggaaaaatg
    25021 tacatccagg gacggcaaaa gatacaatga tcaatgctct acagttagca atcgattttc
    25081 ataatcagct tccagccgat gaagttccag aaaaaacgga aggatacgaa ggtttcttcc
    25141 atttgatggc attggatggg aatcctgaag aagcttctat gagttatatc attcgcgatc
    25201 atgatcgtga aaaattcgaa gcacgcaaag cacaaatcac acatatccaa gaagagttga
    25261 atcagcgatt tgatcaagaa cgaatcaaag tagatatgta tgatcaatat tacaacatga
    25321 aagaaatcat tgaaaaagat atgagcatcg tggaattagc gaaacaagca atgatcgagc
    25381 ttggtatctc tccagtgatc gaaccagttc gtggaggaac agatggttca aaaatctctt
    25441 acatgggtat tccgacgcca aatctatttg ccggaggaga aaatatgcac ggacgattcg
    25501 aatttgtttc tttacaagta atggaaaaag caacagacgt gattgtaaaa attgcagaat
    25561 tgaacacaaa gagttaaaat cgaaaaagaa cagcttatga caaggcgttc gtcccaatga
    25621 tggaatgtca tctgtctaag gctaaagggc aggacaatgg aattggttgt cccgccctct
    25681 tttttgaaga gtaaatagga ggtaaagaat ggaaaagctg ctagtttttt ataacaaaag
    25741 ttcagggaaa gatgagggtg agaaattagc acgctggttt caagattatg taaaagaaaa
    25801 gcagccagaa ttatatgtag aactagctga aactggccca tcgattgatg atgcggaatt
    25861 agtcaagaaa gcagaagcca tagaagctga tactttagta attataggtg gagacggcac
    25921 gattcatcat atcgtccaag cgttccaaaa aacattatct caataccatg tcggattact
    25981 tccaggtgga actgtcaaca accttgcacg tgttcttgag attcccctca aaaaagaaga
    26041 agctgctgac gtgatcctgg aaggcaatgt acggaaaata gactatggtc aagtcaatga
    26101 tgaagtcatt atctctacac tgacaatcgg aatcttagca gatacagcag tttggatcag
    26161 tcaagaagaa aaacagcgtt acggctcgtg gatctttatc aagaagtttt ttaagttatt
    26221 gctgaagaag aaaaaatatc atttggattt agaaacagac gaggagcatt ggaaaggaaa
    26281 atcccaactg ttgacagtca cgatgtctaa ctccgtgggc ggttttacaa attttgacga
    26341 ctcagcgacc ctagatgatg gaaaatttca tgtaacgatc gtaccttcct tagatatttt
    26401 ccgatttatt ttttatttgc ctagaatcat gagaggcaaa ttctatacga tccccggcat
    26461 tacttatttc acagccaaac gcatgaaaat ccaagcgcag gaaaaatctg tgggcactcg
    26521 aacggatgga gacacgacag atgatcttcc agttgaatta tctgttgtat caaaaggatt
    26581 aacagtttat tcaccaaaga aagaagaaaa agcttagaaa tagtagttaa cagaaagttg
    26641 gaagaagagt aatggatgta ttgttacaca atcctttgtg gttttacctt ttcattgtga
    26701 atttttactt attttgtctg atggggtatg ataaacatca ggctagaact agcggctggc
    26761 gtgttcctga gaataatttg atatttgtca gcctgttagg cggtggtttg ggaggattga
    26821 tctctcgaaa agttttccat cataaaactc ggaaaaagaa gtttactata ggattcgctg
    26881 caggtgtact tgttgatttg attctcattt attttttcca ttaaggagca ggagatgtcg
    26941 tctaaaggaa cgaaaactaa aatcattctg aatctgcttt tgctgattgt gatttttgcc
    27001 attatttatt atttaatcaa tcaatcattt gcagatatct ttgccgaatt gctgtctacc
    27061 agtgttgttg ttttggcagc ggctgttata ttagggacag tttaccaaat cgctgaaggg
    27121 cgctcaatca aagaaattgc tgaacctttc gcgccgaatt ttacaacgaa agatgggttc
    27181 ttgacctcta gctatattgc gttttaccga atcgtttcgt ttggtacagg aacgctgatc
    27241 tcggagattt atttttataa caaaaaagga atgaagctat cccagggagc aggggtgaca
    27301 gcactccata tgattatgta caaactggca gtgatcactt atgcattagc tggcttggtc
    27361 atccaattct ctctttttta ttctaatggt ccatcaatga tctggtttat catcgctggt
    27421 atccttttga cgatcgtgat tgttgccttt ttattggcga tgtccgtcag cttgaatgtt
    27481 caaatatttt ttgtcagctt atcgaataag ttatttaaaa gtgagcgttt gcggaaatgg
    27541 gtggatacat gcaatcagca gatctactct ttaagggaaa cggtccaaac cattatccaa
    27601 gacaggactg cgctattgcg gatttatcta tggaatatgt taaaacttgt attttggtat
    27661 gtacttcctt atttgattct gattgaaaac catcctaaaa tagattttct actgaccatt
    27721 tcgtttatca gctttgcagt agtgctttca ggggttattc ctacgcctgc tggtattggt
    27781 tcctttgaat ttgtctattt gttattattc agaccagttg ttggaacagt tgacgcagtt
    27841 tcttcgcttt tactgtatcg tttcagttcc tttatcttgc catttctcta tggatttgtg
    27901 tatgtgattg ctgaacggcg aagagtgatc aaagaagaaa taatagaagt aaaaaaagag
    27961 aataaagaaa atcaagggta ggtcttttat aagatctacc ctttttatca aatcaaagaa
    28021 aaacgttatg gataagataa ttttacgttt gtttggctct ttttttatat acatacaatc
    28081 aattttgttt ttttaagatt tatataagtc gagaaaaaaa gtcaaaaaac tatgtgtata
    28141 ttttgaccaa aattgaccaa agcgatataa tagtttttgt aaagatcaaa gaaataagtg
    28201 atcttacctt taattaggag ggtatacctg tatgaatatt gagaaaatga ctacgacgct
    28261 tcaagaagcg attgctgaag ctcaacagat tgcggtcact cgaaaacatc aagatatcga
    28321 cattgcccat gtatggaaaa tctttttaca atctaatcat tttggtcgaa atttctatac
    28381 ggatgccgga ttggatgtcg aatcttttga acatgaaatt gatcgtctac tggatgagta
    28441 tccagttgtt tctggtggaa acgtccaata tggacaaaac ctcagccaga atttctttcg
    28501 attattgaat gaagcagacc aaatacgtga aagcttcggc gacgagtttc tttcaacgga
    28561 agtcgttatt ttagcgttga tgaaattaaa aaattatccg ttaactgttt atttgaataa
    28621 aaacggatta tctgaaaaag aattgcgtaa aaacatcgaa gagatgagag gaggagaaag
    28681 agtgacctca caaaaccaag aagaacaata caaagcatta gaaaaatacg gcgttgattt
    28741 agtacagcaa gtcaaaagcg gaaaaatgga tccaatcatc ggtcgtgatg aagaaatccg
    28801 tgatgtcatc cgtattcttt cacgaaaaac aaaaaataat cctgttctga taggagaacc
    28861 cggtgtaggg aaaacggcaa tcgttgaagg gcttgctcaa cgtatcgtac gcaaagatgt
    28921 gcctgaaaat ttaaaagata aaacgatttt ttcattagat atgggtgcat tgatcgctgg
    28981 agcaaaattc cgtggtgaat ttgaagaaag actaaaagca gtcttgaaag aagtcaaaaa
    29041 aagtgatgga cgtatcctct tgttcatcga tgaaatccac aatatcgtag gggcaggaaa
    29101 aacagaagga agtatggatg ccggaaatct gttgaaacca atgcttgctc gcggtgaatt
    29161 acatttgatc ggtgccacaa ctttagatga gtaccgtcaa tatatggaaa aagacaaagc
    29221 gttggaacgt cgctttcaaa aggtattagt caaagaacca acagtggaag atacgatcag
    29281 tattctgcgt ggattaaaag aacgttttga gatccaccat ggtgttaaca tccatgacaa
    29341 cgcattagta gcagcagcta ctttatctga ccgttatatt actgatcggt tcttaccgga
    29401 caaagcaatc gatttgatcg atgaagccag tgcaacgatt cgggtagaaa tgaactctat
    29461 gccaacggaa ttagatcaag ttactagacg tttgatgcag ttggaaatcg aagaagctgc
    29521 actgaaaaaa gaatcagatg atgcaagtaa aaaacgcttg aaaaatttgc aagaagaatt
    29581 agctgaactt cgtgaagaag caaatgcgat gaagatgcag tgggaaacag aaaaagaaga
    29641 agtcaattct gtttcagcaa aacgtgctga aatcgataaa gcaaaacacg aattagaaga
    29701 tgcagaaaat aactatgatt tagaacgcgc tgctgtattg cgtcatggta cgatacctca
    29761 attagaaaaa gaattgaagg aattagaagc taaagcaaaa gacagcgaga ttaagatggt
    29821 tcaagagtcc gttaccgaaa atgagattgc tcaagtcgtt ggcagattaa cgggtatccc
    29881 cgtaacgaaa cttgtagaag gtgaacgaga aaaactaatt aaattgaatg aaacacttca
    29941 taaacgagtg attggtcaag atgaagcagt tgatgcggtc agtgacgcgg taattcgttc
    30001 acgggctgga ttgcaagacc caaatcgtcc tctaggttct ttccttttcc taggaccaac
    30061 tggtgtcgga aaaaccgaat tagcgaaagc gttagctgag aacttgtttg actcagaaga
    30121 tcatatggta cggatcgata tgagtgaata tatggaaaaa catgctgtgt ctcgtctagt
    30181 cggagctcct ccaggctatg taggttacga agaaggtggt caattaacgg aagctgtcag
    30241 acgaaatcct tatacaatcg tcttgttgga tgaaatcgaa aaagcgcatc ccgatgtctt
    30301 caatatcttg ttacaagtcc tagatgacgg acgcttgact gattcaaaag ggcgagtagt
    30361 agatttcaaa aatacggttc tgatcatgac cagcaatatc ggttcacagt tactgctgga
    30421 aggcgtgact gctgatggaa cgattccaga agcagtggct gaacaagtca acacgctatt
    30481 acgtggaaac ttcaaaccag aattcttgaa ccgaatcgac gacacgattt tatttacacc
    30541 attgagccta gacaacgtga aaggaatcgt tgacaaaatg gtggcgcaat tggcacaacg
    30601 tctggaacat caagaaatcc tgctgacaat cagtgatgaa gccaaaacgt ggattgctga
    30661 aaatgcttat gaaccagcat atggtgcaag accattgaaa cgatttatca ctaaggaagt
    30721 agaaacacca ctagctaaag aaatcgttgc aggacatgtt atgcctaaat caaaagtaac
    30781 gattacttta cttgatggac aacttcattt caaaacagaa gagctagaag aaatcgtcta
    30841 atcttccatt gagactataa aagaaaaaag gggtctgaca caactagtgt cagacctcct
    30901 tttttcaaat aaacagtgtt ccagaagtag tttcttcgaa aaataagccg aaatttcttg
    30961 aagctgcccg cttctgtcac aacctctttt attaggtatt tttcactttt tctaatttat
    31021 aactttcaaa gtaacgctca tcttttttac tttgagacca tgcaaacaat cccattaagg
    31081 cagcacctat cgtatttgtc agcaagtcgc ccatcgtatc catcaatgct gctcgtccga
    31141 caaacagtgt gccatcagaa gcagcaaaac gttgaagatt catgcctaag aactggtcgc
    31201 ataagaattc ccagaactcc caaaacacgc cgcaaagtcc agcaaacgca aagccgaata
    31261 agaggaacaa ccaaggactg gtttttgata tctcagcatc tttcatcaag taaccaatca
    31321 atccatagcc aagagctgtc aggaccattg gactcaccgc atgtaagatt ttgtcccaaa
    31381 aagagatgat actgatcaaa tgcatccctg tgcctaaaaa gacagagatg aacaagaaaa
    31441 accagtaaaa caaaacgatt gctgctggta ttttaagttt gaaaactttc aaaatgactt
    31501 gtggcatgaa aatcaatgca atccctaata aagattccac gataaatgtg attccttgag
    31561 aagtcgaata tttttgtgtg ataaattcat aaaaattata gcagacaacg aatacaccaa
    31621 aagcaagtaa agctatttgc acctttttga tttctttaat cactgaaagt ccctccatct
    31681 aaaaatcttt ttacttctga aagcaactca atttctgaag aaaccacttt tccgttcaat
    31741 ttgatcaaac ctattgtata taagttcagg tagtgaaatt gattttcagc tgtttcttgt
    31801 agtgcagcga tttttttcgg gtgggttccg ccttgctgtc gagtatcagt atataagccg
    31861 atcactggga tgcctttcgc ataagccaca ccgatttccg atgctacccc ggcatcgatc
    31921 gtcagcccat ctagtaaagc aatcattaaa tcactagcca acactttttc tgtgtcagca
    31981 agagcaatca ttcgactgtc tgcataagca gttttgtcat tgattgcttc attttcttga
    32041 ggaagataga tcgaaagctc agaagagagc tctctgattt ctttaactaa ctgttggtta
    32101 tataacaaat cacttttagc aaacattggt gcggcaaaat aaattttcat ctaaacatca
    32161 tcctttttat caaaaataat cgctaaagta agcttccatg tttggaatga tacgctctag
    32221 tgacttcagt gtttcttcat ctgtttctaa ccgttcgatt cttgccaaat aagaagcacg
    32281 gcgataattc atcatcaagc aagtcaatgt ttggatatcc agtcgaacgg attttcctat
    32341 aggttcattt aagacacgga cttgtccctg ttcatcccat gttaaagcga agacaccatt
    32401 attccaagga gcgacaggat cttcaatgat gaaatgaaaa gcatcagctg ttccaacaaa
    32461 cggaaaccgt tgaaggaatt cttttacatc aacgatccga gccataaaat atggttcgat
    32521 ctgctctttg atctgactat cttcaatcaa aaatgctaaa ggctcatttt tataaatatc
    32581 tccatgtacc cagtagatca tggaaaaatg tgcggaaata aagttccata agccatttcg
    32641 agcttcttga tcaagataga acatttcttt tacgtgaaat atttcttcag ctacccagta
    32701 gaacagaaca cctcttggtt catggttgct atcgtagtag acagcggctg tgcgctcatc
    32761 ttcattttcg aaacgccaat actcttccca atgaaaatca ctgcggaata aagcaccatg
    32821 gttttgttgg gcaaatttgt cataaacgga aaatacgtct ggatgatcaa ctggtaatcg
    32881 ctcaaccata ccacttactg ggatttgttt aggtagctgt gtatctctga ttttaaagga
    32941 aagtttatca gacatgattt cccatccttt acgccgatag taggggatac tgtaaggata
    33001 caaataagag atccattgct tattcttgcg catattatcc aatgcaacga taattagatc
    33061 ttgcatcaat ccatggttag catattctgg ataagttcca actccagtca caccacccat
    33121 tttataacgt gcaccgtgaa tattgacttc acaaggatag atagcgattt gagagatcag
    33181 tttattttcg tggaaccatc cgaacacttt cgatacttcc aaaatcggtt ttttggaacg
    33241 gataaaagct cgtttattct caaacccgct ttcctcgatg tctgcttcag tcacttggaa
    33301 cacataggaa agcaattcat tgaattgatc gatatgttct tgagtgaccg gttttaattc
    33361 aagattttct ctaaaatctt tttgatccat tttttcatct ccatttatta gcttgataac
    33421 agtatagcaa aattctacaa aaaaaacttc tatagctgac taattaaaaa ctctttaaat
    33481 tactgctttt cgttggtata atggaaagtg ctgattatat gaaaagagga gacgctatgg
    33541 atataaagaa aatgaaagaa cgccaagagc agattcgtaa tttttcgatc atcgctcata
    33601 tcgaccatgg gaaatctaca ttggccgatc gtattttaga aatgacgcac actgtgacgt
    33661 ctcgcgaaat gcaagatcag ctgttagact cgatggattt ggaacgtgaa cgtggaatca
    33721 cgattaaatt aaatgctgta gaactcaatt acacagcgaa aaatggagaa acatatatct
    33781 ttcacttgat tgacacccca gggcacgtcg acttcaccta tgaagtctct cgaagccttg
    33841 ctgcctgtga gggtgccgtt ttagtggtcg atgcagcaca aggaatcgaa gcacaaacat
    33901 tggccaatgt ttatttagcg ttagacaatg atttggagat cctgccagtc atcaataaaa
    33961 tcgacctacc cgcagcagat cccgaacgtg tccgtcaaga aatcgaagac gtaatcggaa
    34021 tcgatgctag tgaagctgta ttagccagtg ccaaatcagg gattgggatt gaagatattc
    34081 tcgagcagat cgtggaatat gttcctgcac caagtggaga cttagatgca ccgctaaaag
    34141 ctttgatctt tgactctatt tatgatagtt accgcggtgt tgttctaaat gtccggatca
    34201 cggacggtat ggtcaaaccc ggagacaaaa tcaaactgat gagtaatggc aaaacatttg
    34261 atgttacaga ggtcggggtc ttctcgccaa aagcagttgc tagagacttt ttgatggtcg
    34321 gtgatgtcgg ttatatcaca gcaagtatca aaactgtcca agatacacga gtaggggata
    34381 cagtaacgtt agcagacaat cctgccgctg aagctttacc aggttaccga aaaatgaatc
    34441 cgatggttta ttgtggtctt tatccaattg atacttctcg ttacaacgat ttgcgggaag
    34501 ctttagaaaa actgcaattg aatgatgctg ctttacaatt cgaaccagaa acctctcaag
    34561 cattaggttt tgggttccgc tgtggattcc tcggacttct tcatatggat gtcgtccaag
    34621 aacgcttgga acgggaattc aatctagaat tgatcacgac tgcaccatcc gttatttacc
    34681 atgttaataa aacggatggt acgactgcta cagtagataa cccggcagat tttcctgaac
    34741 ctgtaacgat tcaggatgta gaagaaccat tcgtcaaagc acagatcatg gtcccaaatg
    34801 attttgtcgg tgcagtaatg gaactttctc aacgaaaacg gggagaattc attacgatgg
    34861 attatttaga tgattaccga gtaaatgtcg tctataatat tccgctttct gaaattgtct
    34921 ttgacttttt cgacaaattg aaatcaagca cgaaaggcta tgcctcattg gattatgaaa
    34981 tgtctggtta tcaaaaaagc aagttagtga agatggacat cttgctgaat ggagaaaaag
    35041 tcgatgcatt aagctttatc gttcaccgag actttgccta tgaacgtgga aaagcaatcg
    35101 ttgaaaaact gaaaaaacta atcccacgcc aacaatttga ggtgccaatc caagcagcta
    35161 ttggacaaaa aatcgttgcc cgttcagaca tcaaagcctt gcgtaaaaac gtcttggcta
    35221 aatgttatgg tggagatgtt tctcgtaaac gtaaactctt agagaaacaa aaagaaggga
    35281 agaagcggat gaaacaaatc ggctccgtcg aagttccgca agaagccttc atggccgttc
    35341 tgaaaatgga cgaggacgaa ccgaagaaat agcaagggtt tgtttgaaaa cagtgtaaaa
    35401 aataaaccat gtttacatgg atttgccacc ggtttgccac cggtggtttt tttcggtggc
    35461 aaaaatcaag aattctttct aagattttcc atgatatcga ccgtttcatt tctcatctta
    35521 tctgttacat gcgagtaagt atccatcgta attgaaattc tgctgtggcc caatcgttca
    35581 gagatttctt tcatttttgc gccattttcg agaagaagtg tagcatgagt atgtctgaga
    35641 gaatggaagt taaaagagag ggagagtgca ttcgatatcc tcctagtatt ccatttcact
    35701 acacttggcg taactagctc accgtcttcc ttcgtacata ctgcatttga atcaatgtag
    35761 agctttccat acttcattcg attttctaat tgttgtttct tatgtttttt cagaattgct
    35821 agcaaggttt gtccaataaa aatcgttcga ttggaactgc ttgtctttgg cgtaccatat
    35881 acccatgcgc cgtcattctt taccatttgt ttctctacag taattgttcc atttgaaaaa
    35941 tcgacatcat cccacgtcag accacaaact tcgccaacgc gcattcccgt ataaaatcca
    36001 atattcaaag gaatatagaa aggatgtcct tcaggagtaa tttctagcat atgatcaaag
    36061 tcctcaagag aaatgatttt tagatctttt ttagtcgttg gtcgtgcttc atattttggt
    36121 atttttacat acagcatagg attttgcttg attaatcccc aaggataaac cgccatattc
    36181 agcgcattct taaggacaga gtgagtaata gtcattgttt tcttcgagta acccttttta
    36241 aattcagcat tgatgaaatt ttgtaaaaga gcaggggaga gatccgtaag ttttttcttt
    36301 cctaaataac cgtttatatg atttttgatg gtaaatcggt agttttcata ggtattgtat
    36361 tttagattta gtttaacgta ttcctccatc caaaaatcaa ggtattgttt tactcgagta
    36421 tccgtaccta aaaagtattg tcctgtttcg tcaatatctg ataaaacttt tcgtaaagca
    36481 gcttcggcct ctggtcgggt gtctccgcca actttctcca ctttttttct tgagccatca
    36541 tcattgatat ct
//
LOCUS       DAXLPC010000018        35795 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.018, whole genome shotgun sequence.
ACCESSION   DAXLPC010000018 DAXLPC010000000
VERSION     DAXLPC010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.018"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(196..366)
                     /locus_tag="ACF3UE_000860"
     CDS             complement(196..366)
                     /locus_tag="ACF3UE_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634315.1"
                     /translation="MITIIKPQEKSPVLKFNESNLAHNKMSITDTVFDVMVEQQKKIN
                     NNNRQRKEINQY"
     gene            complement(350..1558)
                     /locus_tag="ACF3UE_000861"
     CDS             complement(350..1558)
                     /locus_tag="ACF3UE_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634316.1"
                     /translation="MTAEIGIMNKSGIVLASDSASTIGDSKVYNTAKKLFTLDSMHSV
                     GIMIYGNAEFNGIPWEIIITQYKKSIGSSVFNTLEEYADNFIEFVKTASFIRSEQTEQ
                     EQMIGVFQKIISGLFESIEVDINFLISQGTQIDKDVLVKLLQTKMNTNLSQQSQTFIL
                     DIEKALFLSNYGEILKDILNSISTMEGVSEAISEEIQSYVYEIIIRDDVYSSPTGIVI
                     AGYGRMDIFPKLYSYNMFGFVMNILKYSEYESAQIGNDNGSLRSTILPFAQSDVVNTV
                     VQGVDPQITNYLSSQVDSFDDNGKNTYINIIKNISEFQQNQFIFPLLNMIALLPVEET
                     AIIAETLLNLTSFKRKYTTSVETVGGPIDVLAITPNDGPIWIKRKHYFDIDNNIGYRL
                     RKERANDYNN"
     gene            complement(1673..2692)
                     /locus_tag="ACF3UE_000862"
     CDS             complement(1673..2692)
                     /locus_tag="ACF3UE_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFD3634317.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGLNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHNKATFEKNYKAYVELARDSAKKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RPDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(2703..2900)
                     /locus_tag="ACF3UE_000863"
     CDS             complement(2703..2900)
                     /locus_tag="ACF3UE_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFD3634318.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASALVAMLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            complement(2916..3158)
                     /locus_tag="ACF3UE_000864"
     CDS             complement(2916..3158)
                     /locus_tag="ACF3UE_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HFD3634319.1"
                     /translation="MKDEAIQDVVERLVRIETKLDNYELLREKAESAKDRADQAYSIA
                     LNNAEDIKEMKANNKWSWGYMIGLGITIIGYFLTKL"
     gene            complement(3236..5455)
                     /locus_tag="ACF3UE_000865"
     CDS             complement(3236..5455)
                     /locus_tag="ACF3UE_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HFD3634320.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPYLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAETKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSINFGDYDYSGNPNLLSKLSYDLIE
                     NQNTSAGTLSKGENSFKYNKISAEVEGGVELYYKRRGIANWLPSNKTLVMTVKLRAGA
                     DYSPVDGKLILIRYRYVDSGTGKIVLDLPINSNSITQEWKEFSITGTTPTFSPQAYHP
                     WIQFRAQDGILGEIEMSYDIKIEEGSTATPFQPNLLAEPYNMCREYPNENIADHTVKF
                     PIESGDHQIYQGYTEEELMIGQTYTITLKGTKPASQTFVAYNHWTARLGELKPVDGLT
                     DVWSLTFTPTNVVAMPKLFRVYQYPQSTVGACQIDWLKIEKGNTRTPNISEYKYRGTG
                     MRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSKINSQLTASINEV
                     DTTAKGAQTKANANATAIDELDNKIDERINDTATTAFYGAQGEVSNKTKVAEYGVGTG
                     YTTTAVGETHFERQSNGYVKCLKAGKYSISAQIRVQLGGKYASWLYTDLYKDGTSVDN
                     LVSYGVDALQNRFAASGNIVTDLEVNDVLNMRTEIGVANGILQFTSCRTLVLTRLSD"
     gene            complement(5479..7770)
                     /locus_tag="ACF3UE_000866"
     CDS             complement(5479..7770)
                     /locus_tag="ACF3UE_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFD3634321.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKALAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLHHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KEWLKTNVDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGTDYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            complement(7780..8517)
                     /locus_tag="ACF3UE_000867"
     CDS             complement(7780..8517)
                     /locus_tag="ACF3UE_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFD3634322.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            complement(8568..11987)
                     /locus_tag="ACF3UE_000868"
     CDS             complement(8568..11987)
                     /locus_tag="ACF3UE_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFD3634323.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQENWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            complement(12004..12186)
                     /locus_tag="ACF3UE_000869"
     CDS             complement(12004..12186)
                     /locus_tag="ACF3UE_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634324.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            complement(12189..12551)
                     /locus_tag="ACF3UE_000870"
     CDS             complement(12189..12551)
                     /locus_tag="ACF3UE_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634325.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            complement(12571..13179)
                     /locus_tag="ACF3UE_000871"
     CDS             complement(12571..13179)
                     /locus_tag="ACF3UE_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFD3634326.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            complement(13191..13595)
                     /locus_tag="ACF3UE_000872"
     CDS             complement(13191..13595)
                     /locus_tag="ACF3UE_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634327.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            complement(13588..13989)
                     /locus_tag="ACF3UE_000873"
     CDS             complement(13588..13989)
                     /locus_tag="ACF3UE_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634328.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            complement(13979..14332)
                     /locus_tag="ACF3UE_000874"
     CDS             complement(13979..14332)
                     /locus_tag="ACF3UE_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFD3634329.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            complement(14322..14633)
                     /locus_tag="ACF3UE_000875"
     CDS             complement(14322..14633)
                     /locus_tag="ACF3UE_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634330.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            complement(14630..15505)
                     /locus_tag="ACF3UE_000876"
     CDS             complement(14630..15505)
                     /locus_tag="ACF3UE_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634331.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            complement(15515..16675)
                     /locus_tag="ACF3UE_000877"
     CDS             complement(15515..16675)
                     /locus_tag="ACF3UE_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFD3634332.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            complement(16675..17361)
                     /locus_tag="ACF3UE_000878"
     CDS             complement(16675..17361)
                     /locus_tag="ACF3UE_000878"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFD3634333.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            complement(17324..18502)
                     /locus_tag="ACF3UE_000879"
     CDS             complement(17324..18502)
                     /locus_tag="ACF3UE_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFD3634334.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            complement(18522..20216)
                     /locus_tag="ACF3UE_000880"
     CDS             complement(18522..20216)
                     /locus_tag="ACF3UE_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFD3634335.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            complement(20194..20508)
                     /locus_tag="ACF3UE_000881"
     CDS             complement(20194..20508)
                     /locus_tag="ACF3UE_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFD3634336.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            complement(20611..20892)
                     /locus_tag="ACF3UE_000882"
     CDS             complement(20611..20892)
                     /locus_tag="ACF3UE_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634337.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            complement(20897..21241)
                     /locus_tag="ACF3UE_000883"
     CDS             complement(20897..21241)
                     /locus_tag="ACF3UE_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFD3634338.1"
                     /translation="MNEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            complement(21267..21434)
                     /locus_tag="ACF3UE_000884"
     CDS             complement(21267..21434)
                     /locus_tag="ACF3UE_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634339.1"
                     /translation="MYRPQYLEQKYEVITVQNGNGEIVRKYRRPIKSDTYKRKESNEV
                     IPLYGKRIAKH"
     gene            complement(21471..21845)
                     /locus_tag="ACF3UE_000885"
     CDS             complement(21471..21845)
                     /locus_tag="ACF3UE_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634340.1"
                     /translation="MEDKMYLRQKVFTKKDIENQINGFIQKLENANSYLINKELNKAY
                     DQWKEVYDELKLIQNETKLVRTEKKNENSFFFDGYAILMLETVAKQNIKAPKKELSDN
                     IDNALAELRYYVMQIKDVRITR"
     gene            complement(22191..22604)
                     /locus_tag="ACF3UE_000886"
     CDS             complement(22191..22604)
                     /locus_tag="ACF3UE_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFD3634341.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            complement(22680..22976)
                     /locus_tag="ACF3UE_000887"
     CDS             complement(22680..22976)
                     /locus_tag="ACF3UE_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634342.1"
                     /translation="MKLKDGFYSSSHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKWLAKSKDNLAVVRLVDIELINDK"
     gene            complement(22976..23182)
                     /locus_tag="ACF3UE_000888"
     CDS             complement(22976..23182)
                     /locus_tag="ACF3UE_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634343.1"
                     /translation="MKIYVVKFGNQFYRSDERSIGANTLSIVDILQSARWFDNLEEAN
                     QVSRRLGGLAQVYELVTIDHEEVE"
     gene            complement(23179..23376)
                     /locus_tag="ACF3UE_000889"
     CDS             complement(23179..23376)
                     /locus_tag="ACF3UE_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HFD3634344.1"
                     /translation="MNNRHRRVTKLRKQELNALKAKFEKEYGISIEEAYKVASQCVAD
                     ASEAIRKFGISILDIKWEDTE"
     gene            complement(23383..23613)
                     /locus_tag="ACF3UE_000890"
     CDS             complement(23383..23613)
                     /locus_tag="ACF3UE_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634345.1"
                     /translation="MKYEIALSEADVQSIINGRKVKFKLSDGTEIVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            complement(23636..23941)
                     /locus_tag="ACF3UE_000891"
     CDS             complement(23636..23941)
                     /locus_tag="ACF3UE_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634346.1"
                     /translation="MNVQVYLKRDLARFPRSWDEYSCPFEAEEESYLMSANMIEITRD
                     DADEVDKKRSWYSVSNPMYTAVIEDYHISDRFILVDLERPKKRIKQYRRCGFSTKKW"
     gene            complement(23938..24135)
                     /locus_tag="ACF3UE_000892"
     CDS             complement(23938..24135)
                     /locus_tag="ACF3UE_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634347.1"
                     /translation="MKAYTIKFYGNKTFVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEAE"
     gene            complement(24138..24413)
                     /locus_tag="ACF3UE_000893"
                     /pseudo
     CDS             complement(24138..24413)
                     /locus_tag="ACF3UE_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876801.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
     gene            complement(24568..24765)
                     /locus_tag="ACF3UE_000894"
     CDS             complement(24568..24765)
                     /locus_tag="ACF3UE_000894"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634348.1"
                     /translation="MNKNKQELINELKRISLEKQHKALTHPESKNYYEGMVMAYSQVV
                     HMVNTVLKLDESQKPVMPKFF"
     gene            complement(24758..25078)
                     /locus_tag="ACF3UE_000895"
     CDS             complement(24758..25078)
                     /locus_tag="ACF3UE_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017547333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HFD3634349.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKATANIEFYYNEIQKGFEQMRELDKQTNWRKKLHQDRFKFVEKYKEILDEYLE
                     DSNE"
     gene            complement(25078..25377)
                     /locus_tag="ACF3UE_000896"
     CDS             complement(25078..25377)
                     /locus_tag="ACF3UE_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634350.1"
                     /translation="MDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPKRK
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRAKRENVDSKGRQFKHVEEK"
     gene            complement(25380..25541)
                     /locus_tag="ACF3UE_000897"
     CDS             complement(25380..25541)
                     /locus_tag="ACF3UE_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFD3634351.1"
                     /translation="MTTEEVIQMRIRNIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RRVIRRLEE"
     gene            complement(25556..25915)
                     /locus_tag="ACF3UE_000898"
     CDS             complement(25556..25915)
                     /locus_tag="ACF3UE_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HFD3634352.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQEK
                     FELMPKFELEGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            complement(25912..26763)
                     /locus_tag="ACF3UE_000899"
     CDS             complement(25912..26763)
                     /locus_tag="ACF3UE_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3634353.1"
                     /translation="MESLASTMEKLIRRVLVQSGKCPECSEPLYSWRGKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSYVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            complement(26781..27596)
                     /locus_tag="ACF3UE_000900"
     CDS             complement(26781..27596)
                     /locus_tag="ACF3UE_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HFD3634354.1"
                     /translation="MSDKQKKRYYWLKLKEDFFEEDTIEWLEEQPNGKEYCLFYLKLC
                     LKSLKTEGILVRNVGNLMIPYDPESLAKLTNSNTDTVKVAMDLFNKIGLIKILDSGEI
                     YLNQLSELVGSETEYARQKRIQRAKEDNVQKLSGKGRLEIELEKDIDIDIDKEEKKGK
                     YSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADAIRLMEERDKASIEAIEYVINWLP
                     TNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLPI"
     gene            complement(27615..28301)
                     /locus_tag="ACF3UE_000901"
     CDS             complement(27615..28301)
                     /locus_tag="ACF3UE_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFD3634355.1"
                     /translation="MFKPLIDSYSAVLKKFKGNDIDATINEEVNIERLKTMYDGYDGD
                     RIIEIRFIDPRRFTAQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLNIGG"
     gene            complement(28307..29041)
                     /locus_tag="ACF3UE_000902"
     CDS             complement(28307..29041)
                     /locus_tag="ACF3UE_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFD3634356.1"
                     /translation="MSEGTKRNDNKLFNSLYKITVNDVVEKRNKLTYLSWAWAWAEVS
                     KICEEVDYEIYRDPETHRPYLFDEKTGYMVFTSITVNGVKRDMWLPVMDGANKAMKDE
                     PYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLGLYIF
                     AGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITADDSKW
                     TKRDLGILKRGVNWLEDQYREETKEK"
     gene            complement(29034..29375)
                     /locus_tag="ACF3UE_000903"
                     /pseudo
     CDS             complement(29034..29375)
                     /locus_tag="ACF3UE_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(29554..30279)
                     /locus_tag="ACF3UE_000904"
     CDS             complement(29554..30279)
                     /locus_tag="ACF3UE_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HFD3634357.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFKKKHKHVLEAIESIKRSVENS
                     ANVEDGSNFGQMFVEGNEPDSYGRSRRVYFMNRDGFSLLAMGFTGSKAINFKLKFIEA
                     FNEMEDVIRKNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNM
                     KVMEVLGGKESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLP
                     ETAIRMEIDQLNRQQRLFGDENE"
     gene            30332..30808
                     /locus_tag="ACF3UE_000905"
     CDS             30332..30808
                     /locus_tag="ACF3UE_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634358.1"
                     /translation="MRKKLNYILTATLTIYIILFITLSFLSSIKKIPFITLNKNSILK
                     EFNNIDYIAFLKLFSVCVLISCVIIFIVAKTCWTMLNKNQRDVENIAIFLIKITSSIS
                     IIIPMTVTFSKEQFNVAATYLSFIALFSFVLPKRNKSNFDNKELDEVRNSSPKEQK"
     gene            complement(30814..30996)
                     /locus_tag="ACF3UE_000906"
     CDS             complement(30814..30996)
                     /locus_tag="ACF3UE_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634359.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSKQALIGTIVYMVWIFMGLDE
                     AEHRAKKASREGLTKI"
     gene            complement(30983..31321)
                     /locus_tag="ACF3UE_000907"
     CDS             complement(30983..31321)
                     /locus_tag="ACF3UE_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFD3634360.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            complement(31337..31540)
                     /locus_tag="ACF3UE_000908"
     CDS             complement(31337..31540)
                     /locus_tag="ACF3UE_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3634361.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            complement(31556..32332)
                     /locus_tag="ACF3UE_000909"
     CDS             complement(31556..32332)
                     /locus_tag="ACF3UE_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFD3634362.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKERYYPQMDLEEIG"
     gene            32412..32582
                     /locus_tag="ACF3UE_000910"
     CDS             32412..32582
                     /locus_tag="ACF3UE_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634363.1"
                     /translation="MNKKIAADLVVAWLNHESQVSTKGESISPKEIAQAYLDIHYAVI
                     YGQLPEDRKNDD"
     gene            complement(32579..32719)
                     /locus_tag="ACF3UE_000911"
     CDS             complement(32579..32719)
                     /locus_tag="ACF3UE_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634364.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            33020..33340
                     /locus_tag="ACF3UE_000912"
     CDS             33020..33340
                     /locus_tag="ACF3UE_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3634365.1"
                     /translation="MNPYEKIKELTKQNGISVRELEKRLGYSNGYFSKWKSVSPNSEG
                     LAKVSDYFGVSVDYLLGREKKETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            33358..33789
                     /locus_tag="ACF3UE_000913"
     CDS             33358..33789
                     /locus_tag="ACF3UE_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFD3634366.1"
                     /translation="MYLKLKEMLSGYNLKLIYMEMEEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            33918..34502
                     /locus_tag="ACF3UE_000914"
     CDS             33918..34502
                     /locus_tag="ACF3UE_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HFD3634367.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDLPVGTDVEVYGPDDKKSETYANENTMGAVAPGKQM
                     DVTAHFTLNQTGEIEIHFSPLVSFEKAAIFKATV"
     gene            34616..35755
                     /locus_tag="ACF3UE_000915"
     CDS             34616..35755
                     /locus_tag="ACF3UE_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3634368.1"
                     /translation="MARFVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
BASE COUNT        10296 a         7296 c         5392 g        12811 t
ORIGIN      
        1 ttcattcttc atgttgtgat ggcatattta ttattacaca tttaatagca aaaaactaga
       61 ttgtacttat tctttgtaaa atatattatt ttatgctatt atttacttta acttttcaga
      121 aaaataaaaa aagacctcgc ccaagattga gcgaggtttt aaattatgac tgcaaaaaac
      181 gcaacagaaa aaacattaat attggttaat ttcttttctt tgtctattgt tattattaat
      241 ttttttttgt tgctcaacca ttacatcaaa tactgtatca gttatactca ttttattatg
      301 ggctagattg ctctcattaa atttcaaaac aggggatttt tcctgaggtt taattattgt
      361 aatcattcgc tctctccttt cgcaatctgt atccaatatt attatcaata tcaaaataat
      421 gttttctttt aatccaaata gggccatcat taggtgtaat agctaaaaca tcaattgggc
      481 cacctactgt ttctacagaa gtagtatatt ttcgtttaaa actggttaaa tttaataaag
      541 tctctgcgat aattgctgtt tcttcaactg ggagtaaagc aatcatgttt agtaacggaa
      601 atatgaattg attttgttga aactctgaaa tattctttat aatattaata taggtatttt
      661 ttccgttatc gtcaaaacta tcgacttgac tcgacagata attagtaatt tgtggatcta
      721 ccccttgaac tacagtattt accacatcag actgagcaaa tggtaatata gtagatctta
      781 atgaaccatt gtcatttcct atttgagcac tttcatattc tgagtatttc agaatattca
      841 taacaaatcc aaacatatta taagaatata gtttagggaa aatatccatt cttccatatc
      901 ctgctataac tattcctgta ggggaagaat aaacatcgtc tctaattata atttcataaa
      961 cgtaactttg aatttcctct gatatagctt ctgaaacacc ttccattgta gaaatactat
     1021 taagaatatc ttttaatatt tctccatagt tactaagaaa taacgccttt tcaatatcta
     1081 aaatgaatgt ctgggactgt tgagacaaat tggtattcat ttttgtttgt aataacttca
     1141 ctaggacatc tttgtctatt tgtgtacctt ggcttattaa aaagttaata tctacttcta
     1201 tactctcaaa taaacctgaa attatttttt gaaaaacccc aatcatttgt tcttgctcgg
     1261 tctgttcact tctaataaaa gatgctgttt tgacaaattc tataaaatta tccgcgtatt
     1321 cttccaaagt attaaaaaca gaactaccaa tgcttttctt atattgagta atgattattt
     1381 cccaaggaat accattaaat tcagcattac catatatcat gatacctaca gaatgcatgg
     1441 aatccaaagt aaataatttt tttgcagtat tatatacttt gctatctcca atcgtagatg
     1501 ctgaatctga agctaacacg attccacttt tattcataat accaatttct gctgtcacaa
     1561 tttcacctgc ttttttcttt tattatctac ttaaataaac atcttgtaaa tatttttttg
     1621 atttaacgtt aattttcaat tctatgtact gctcctcaac gaggagctat ttttatcgtt
     1681 taggaatatt taaataccaa cgtttgtcat ggaaatcttg cgcaccgcct ttagtgtttc
     1741 cttctggatc attcgttgcc cgcatcatga cgtatacttt cttattaggg aaattgcgca
     1801 tgttaaaaga tacatgatag ccaacgtttc cagaagtatt ataagcttga tttacatccg
     1861 gtctataaat tccatcagct cttactcgag ctaattcttt cccagtattg tagtccataa
     1921 tgaaaatata ctcgtattta tagttagcga tgtgccatcc agcgacgtgt aagtttgcat
     1981 tttcaatttc cccaaactga tcaatatgag cgtagtttgt tccatctgtc agcgtaggat
     2041 tagctgcacc agctcgtgtt ggatcaatga caggcttgtt ttcagaagtt gttggatttt
     2101 catcggtaaa tccatgagct aaatcatatg ctaatttttc tttacttacg cccatttcag
     2161 aaagataacc gtaaggatct gtatgatcgc cccaaatatt ttgtgttacc cataaatgtg
     2221 atttgattcc tggttggtta taaggagtgt ccaatgtaag cggaataccg tatttcttag
     2281 cggaatctct cgccaattca acgtatgctt tatagttctt ttcaaaagtt gctttattat
     2341 gtgtgtgttg taactcaatc tgcacaggac tgttggcatt agcatacgaa ccagcaccgt
     2401 actgtacata accaggttgt ccaacttggt aaacaattcc accgtctccc acaatataag
     2461 cagtataagc actagtccat gaacgttgca tatattgcgc ttcattgcgt cctgttgctg
     2521 tttcattagc cgtttcatgc agtaaaatgt actgattatt tgctacttgt gagctacctt
     2581 cgtttaggcc caaattaaat tcattgttaa tcgtataggc gaacccatta attggcaata
     2641 aaaaaagagc cgttaatagg ctcatcgcag taatagtaat tttctttttc atttgtttcc
     2701 tcctattttt tcaaattata agccgacaca ccagtgataa cgcctaaaaa cgtggctact
     2761 gcattgatag tcagaactgt catatctgtt ccattccatc cataggcttt gcctaacatg
     2821 gctactaaag cagatgcagc tggtaatact gttaaaaccg tccatttaat gacttgataa
     2881 tacttatcgg gtaaaatcat ttcttctcac ctcctttaca atttagtcaa gaaatagcca
     2941 atgatcgtaa tgcctaaacc gatcatgtaa ccccacgacc atttattatt ggctttcatt
     3001 tctttgatat cttccgcatt attaagcgca atagaatatg cctgatccgc tctatctttt
     3061 gcactttccg ctttttcgcg taataattcg taattatcca gtttcgtttc aatacgcact
     3121 aagcgttcta ccacgtcttg tattgcttcg tctttcaacc aactatcctc ctttcattgc
     3181 aaaataaaaa acaccctcct ttgagcgtgt tgatagcaaa attataaata ttgtattaat
     3241 cagatagtct agtcaagact aaagtacggc aagatgtaaa ttgtaaaatt ccatttgcaa
     3301 cgccgatttc agtacgcata tttagtacat cgtttacttc taaatcagtt acaatgtttc
     3361 cgctagctgc aaatctattt tgcaaggcgt cgaccccata agatactaaa ttatcaacag
     3421 aagttccatc tttatataaa tcagtatata accatgaagc atatttcccg cccaattgca
     3481 cacgtatttg cgcactaatt gaatacttac cagcttttaa gcatttaacg tatccgttag
     3541 attgacgttc gaaatgtgtt tctcctacag ctgtagtagt ataccctgtt cctactccat
     3601 actccgctac tttcgttttg ttagagactt caccttgtgc gccataaaat gcggtagtag
     3661 ctgtatcatt aatgcgttca tcgatcttat tgtctaattc atctatagca gtcgcattag
     3721 cattcgcttt tgtttgagca cccttagctg tggtgtctac ttcattaatt gaagcagtca
     3781 actgcgaatt aatcttcgat actttcccat cggtataatt gtttgcttta ccagtaattt
     3841 cagaaatttt aatatctgtg gccaaattat cttcgacata ttctggtgct agatcccaaa
     3901 cataatcttt tggattgttt gaatcacgca taccagtacc acgatattta tactcactaa
     3961 tattcggagt tcgtgtgttg cctttttcga tcttgagcca gtcaatttgg catgcgccta
     4021 ctgttgattg tggatactga taaacacgga aaagtttagg catcgccaca acattcgttg
     4081 gtgtgaatgt tagagaccat acgtctgtca gcccatcaac cggctttagt tctcctaaac
     4141 gagcagtcca atgattatac gctacaaagg tttgacttgc gggttttgtt cctttaagcg
     4201 tgatagtata cgtttgacct atcataagct cttcttctgt gtaaccttga tatatttggt
     4261 ggtcgccaga ttcgattggg aacttaactg tatgatcggc aatattttcg ttaggatatt
     4321 cgcgacacat gttgtaaggt tctgctaata agttaggttg gaatggtgta gctgttgagc
     4381 cttcttcgat tttgatgtca tagctcattt ctatttcccc aagtatccca tcttgagccc
     4441 taaattgtat ccaaggatgg tatgcttgtg ggctaaatgt tggagtagtt ccagtaatac
     4501 taaactcttt ccattcctga gttatcgaat tactgttaat aggtaagtct aaaacaatct
     4561 tgccagttcc actgtcaaca tacctatatc taatcagtat aagttttccg tcaactggac
     4621 tatagtccgc tccagctcta agcttaacag tcattacaag cgttttatta gatggtagcc
     4681 agttagctat acctcttcgt ttataatata gctctactcc accttccact tcagctgata
     4741 tcttattata tttaaacgag ttttcacctt tagaaagtgt tccagctgaa gtattttgat
     4801 tttcaattaa gtcgtatgat agcttactta acaaattagg atttccacta taatcatagt
     4861 caccaaagtt gatgctgtta ctgtacatca cttgtaagtt acctaactta gaaatttctt
     4921 ctttcagagc atctaacttg tcttgtagcg ttttagcttg accagttaaa tcagtaatct
     4981 gttgatttaa gctatccact ctacctttag tttcagccat aaaagcatca aaagtttcat
     5041 tatactttcg aatcaactct tctaattgcg aaacatattc atcggcttga ccttgcgaaa
     5101 tgtcagacac tcctagtgag aaaaaaatga tatcttgcgt tgttagaatt tgattgtctt
     5161 ttctatattc tacgtagcag tgtttataat atcctgcttc actcataaat gtgccatcaa
     5221 gagaaaacgt gacttcttca ctagttacgc tagttgcaac actatctacg taacggttag
     5281 atggtgttgt tccttttaaa gtaaatgttc cgccactcgt atccatctgc aagccattta
     5341 aatatggttt aaccgtcacc gtaatccctt tatcaccctg acgagccata atagctttgg
     5401 tgtagtttaa ttctttgctg aaatctaaag ccaaattata taaactgcta gccatttata
     5461 tacctccttg tcttcgtttt aaaaacgttt ttggtcaagc actgtgctat catatgctgt
     5521 atcctctttt aatctaatat cttcataccc tagacggtgt gccactaaat tccatctaac
     5581 taatacgttt ggcttactag tttcaatgat gaaatggtca atatcttcat gagtaacagc
     5641 acacaaaact agttctgtag gtgtcacatg tgtcatatac cgacttagat ttactgtctc
     5701 agcaaacatg gggtcaatat caacacgaac tttaccatcg tcacctgtaa cggcttcccc
     5761 ataatcagcg aaataatatt ctggagtttc ataagcgttc aatagtcgtt gtccataatg
     5821 ttctgttggt acagttgagt ttttagtacc tctaacagta aaatctttat atacttgtac
     5881 cgttgattgt tcaaacctag caagtttccc atcttcccat gaaccaaaaa aacaacctgg
     5941 taacgttagc ataccatcac tagtaaattt catagtccta ccagctacct taaattccca
     6001 tgagttaccc gcactaccat taatgcttaa agaactaccg tcgccagaag ttacataact
     6061 agcattgcta tacctgaaat tgggcgcacc aaaagataga aacggtctgt tattaccatt
     6121 atcccacgta ctaaaaacca agttaccctg tggatttcta atcatgaaac caccaccagt
     6181 tttcatggtg tatgatacaa taccggcatc agcacttaca taatcacgtg cttctagctc
     6241 cataatatct ttgttaactt tttttgagta ccaagtcatt ttgccattag caatacttgt
     6301 tctataatca gtgccatcac taattaatgt agtacctcta atagtaattc ctactatttc
     6361 accagccgta ataaacgagg cattgaatcc gccatctaat gtccatgcgg tttcatatgt
     6421 tccattaatg ccagttttag aaaaaccaat accagcattg ttgatttgta aaacattcct
     6481 tgcggtattc ttatctggtg tgtccataat caaaatacga ctaggcgctt ctttaggatc
     6541 taataaaaca taaccaccat tttgaccagt aatcatatca gtttgatgat ctacaatatc
     6601 attgattaaa tcactgattt cgccaccatt tttcaattga tcaatggcat cattaatcaa
     6661 attgcttaca ttattctctg tgttttctaa gaagtttgtt ttgacgtttc ctacaactaa
     6721 tttatcgtat gaattggtta gaacattaaa cgtatattcc acaattctcg ctgacatatt
     6781 cacttttaac tgtggatgat acacatctac tccgtcaccc atcgaaactt tttccagatc
     6841 aacaaatttt tcataacctc tttgatgtct caatggtact aattcaatcg aaccactcac
     6901 ttgtggtttt tgtttgtcta cgttcgtttt caaccattct ttagcagctt cccttaatgt
     6961 ggctacatca gtcgctttgt ctttaaaatc aacaaaagaa acatatccag caggataatc
     7021 atccacgtaa tccgtgaaaa tgacttcttc tggtagagtg atctcgtctt ctccttctga
     7081 agaactgcta atgaatggat aaactccaac taaaacgctt tgagcatcta tctctaagtc
     7141 aagaccagtt aaatttttag tataaatcgc tttgatttta tgatccgtac ctagcctttt
     7201 ttcatgatgt aatgtgttat tatctttaag aaattcccca tgaaatcgat ctagaataga
     7261 tccctctttt ccaccaaaga attctaaaaa attcgctttt tctatcttca cattagcaag
     7321 cgtatctact aatgacgaga aagaaaactg cgaagggata gctggtttcg ctaaagcttt
     7381 tgcgttttgc catgcctgag tagcagtgat tttttctgtt ccgctgtcat atttattcaa
     7441 caccgatttt cttatatcat tgaaaatagg ttcagctttt acttctatcg tattgcctat
     7501 tacagaagtt tttgcataat aaatccgtag acgctgtttt gctcgatttt catctacata
     7561 acactgaata atacgtcctt ctacaatcaa atctgcatta gttccgctta ttggataagt
     7621 accctgaaat atctcggctc cgtttagttt attgctaaca gtagctgtta accagtctga
     7681 caaagcgcct aaaccttgcg tatcatataa atgttcagct aaattattcg cgtcattttt
     7741 atcgtaaata gttattaaat tatcgatcat ctatttcacc taccttaacc cgttacgata
     7801 aatttgtatt ttgctcaaac cagtgcaatt aaaatgattg atatccactt gcaatgtcgg
     7861 atattgcatg gtcttcattt tgttggaccg atctaaaata tctccgtccg attgctcttc
     7921 gtagcaaagc atcaaatcac tatcaatgac tacatcagtt cctgctacta agccttcgaa
     7981 actaaacaca taatcattta agatgaactg gcatgaagta gctgaaggag tgatgataat
     8041 ctttggaaaa ctttcttcta aactattatt cagcaagtta aatgactgtg gtttatctac
     8101 ggttataggt acatcttctt gaactcttgc gaatggtttc gcagtaatat ttacatcgaa
     8161 ctctccccat tcaacaatat cgttttctgc atccccaata tcgatagtct ggataacgta
     8221 atagacgttg ggatcgtcag agaattctaa tttctttgca tagtttaacc aatgacgcat
     8281 gatataaaac gattgcttga acgcttgatg gtcttccaca tcctctaaat agttatagtg
     8341 caatgtaaac gacatgtctt caaacgagta atcttgcact aagccaccta accttcctaa
     8401 aacagaagtc tcaactctct gcctttttgg agaaggtatg gttggtcttt ccgctaaagc
     8461 caatttatgc aaataatcag gaaatccatc gattatagaa tgtatacaat cagtcatttt
     8521 ttcacatcct ttttaatact aaaaaaacag gagaaatact ctcctgttta acgccatgcc
     8581 gaagcattat cattttgaac ttttgtaatg ctatcaatga tttgttgagt tgtttgcttc
     8641 atagtaactt catctgcgtt accatcaatt gtgaaattga attcgtagtt gttcacaggt
     8701 tgaatcgttt gtgccctaga tgaaactgat gtgctactca agatacgatc accaatttct
     8761 tgcagcacag atcttttcaa aggtaaaact gcttcaggtc ctgcttcacc gacaccgata
     8821 atattcggag aattaaacac actacctttc gcataccaat caacacccaa cgttgggatt
     8881 tttcccttca atggattgaa ttccccactc aatttaaaat gtggtaacgg aatatgtggt
     8941 atcgaaatat tcagattatc aaagatgcca ctgattttat ctctaatcca atcaatcgga
     9001 gcgctaacag tctttttgat accttcccaa atgttagcaa ttgtactttt aacattattg
     9061 aatatgtcgg aaacaatacc tgttagattg gaccaaccgc ttgaaattgc attttttcca
     9121 tcgtttactt tggagctaat agtgcttgta attccattcc aaagattcaa agcagtgttt
     9181 ttgataccgt tccaaattcc gctgatccac gaagatatac tattccaaac actttgaatg
     9241 gcacttttag ctgcgtttat agcattgctt atactactag tcacactatt ccagatattt
     9301 gatgctgtag agctgattga attccaaatt ccacctaacc aactagatac agttgaccaa
     9361 atattttgaa ttactgtagc agctgcttgt accaagctag tgattgtatt cttgatactg
     9421 ttccaaatac tagaagctgt tgcactaatt gaattccaaa tatttgaagc cgtagtacta
     9481 atagatgtcc atataccatt ccaccatgcc actactggat caaatatagt atggaatgta
     9541 gttacaattc cgttccaagc gatgcttatc cattgtgtca tagtatccca agtattttta
     9601 aggaaatcag aaataggtgt ccaaacagct tgccaagctg cgcctaataa ctgtccagct
     9661 acatcaaaaa tacccacgat aatattaata ccagcttgaa tcaatgacgt tattaatgtc
     9721 catggtattt gaacaattcc tacaatgtct gcccaaataa tcgaccatac ttctttgact
     9781 ccgttccaaa tatttgaaac ccaatcaacg aatgtttgcc aattttcttg gactccttgc
     9841 cagatgttgg aagctccttc aactaatccg ctccataact ctccaaacca atcggaaact
     9901 ccttgccaaa tatcttgaac ccaatctaca aatccagacc aggtttcttt aactccatcc
     9961 caaactgatg aggcaccttc ttttatactt tcccaagtac cacccaacca atcagtgaat
    10021 ttactccata ttcccttaaa ccagtcagta attgcacccc agttttttat aattgctata
    10081 actccagcaa tagcagtaat aactgctcct attattaatg tagtaggacc acctagagcc
    10141 atgaagccaa ctattattgg cattaataaa gtaaatgcag cagtcaatcc gccaattgct
    10201 acggcataat cctgtactgg ttgtggaaga ttattaaacg catcagccat ctttcctaga
    10261 aaatcaatta ctggttcgag tgcatctatg attgtgttgc ctataggagc taatgaatcc
    10321 tttaattcag ctattttccc gttcaactct tgcaacggag tagtagaatc ttcattcatt
    10381 ttttgtgcag atccactaac atcatcaaat gtatggttaa catcagttaa agattggaca
    10441 actttcatcg cattatcttc gccaagcgca gaccaaattg tcgaagcttt atttaattgg
    10501 tcgtattgac catccatatt gctaaaatct tgaatcatgg aattaataac gtctttttgt
    10561 gttcctccgc catttttcca ctcttcaaaa gcttttctag tactttcact aaacatatcc
    10621 atgttttgct caaatcgacc atctgttaac gatattccca tttccttaac taagtcattg
    10681 actttatcaa ggttataagc acccgcatct aaaccatttt gaagcattcc gaacgtttca
    10741 tcagctgaat atcccatttg actccataat tggctatatt ctgccatatt gtcgcctaat
    10801 tcgtgcgttt tatctaaacc gttttgagta cccgaaacca ttaaatccat tgcatcttga
    10861 gcactcaagc cgaaattgac cattaagcca tttacaccac gtaacgtttc atccatatca
    10921 gcgcccatgg tgttttctag gaccatagct tgttccgtga tattttgtaa atcttgatta
    10981 tttaaatcgc ctaaattacg ctttaccaaa atcaatgcat ctgtggactg atctaacgat
    11041 tctccaaaac ctttataata aatgtctctg gctacattcg ttaattcttc agcctcttgt
    11101 ttagacaaac caaaattagc ttgtatctta ctctgggaac tacctacact gttagcagag
    11161 tccactgctt gtttccctaa ttctgtaagc ttatcgccaa tgtcgcttaa aacgtcagaa
    11221 gcttccatta aattattcat atctattttg cttccgatat cgtccaagtt agttgtatct
    11281 acatttttag cagcttgtcc taactcttca aattcacgtt cagcatcatt aagcttcgct
    11341 tccatctgca ttgcttctgt ggatgtagcg ccaaattcag actgtgtagc ttctaactgt
    11401 cgtcttagga tatctatcgt tttctccgca ttttcagatt gttgagaaac atattcttgg
    11461 gctttcgcta atttctcggc ttcagaagct gattgaccag cagttgcttg ccattttttg
    11521 tattcggatt caatcagaga agcactagct tgaacatttt tttgttcact atccaactgt
    11581 tgcattgtag actcgtacgt ctgtatttcg ccttttgctt gagctagtgc attactcgtt
    11641 ttatcaattt cgtttgacaa acgttgttgc gctgtttgtt gattaatcag ttctctttca
    11701 agtttctgaa cttcggtgga attttctcca taatattttt tcgcattggc taaacgttgg
    11761 ctagttactt caactttttg actttgtaat tcatactgct tttctaaaga agataattta
    11821 cttcctaact tgtctgattc agaaccagtc tgttgtaatt gagcttgttc tagttttaat
    11881 tctgctctat ttttagttaa ttcagcactg atttctttta acgtagattt caatccgtca
    11941 tcgttagcta tgaaagttac ttctgcttct gttctctttt tagccatttt ttacctcctt
    12001 tctttagttt ttctgggatt ggtttattgc atagtttttc catccttcat aagcactctt
    12061 gttgtaagcc atttgcaaaa tgtcatctaa acagatatcg cttaaaacca aatctgaagg
    12121 catagaaaaa acgtcggtca acatcgaata gacatcgacc cacgtttcaa ctaagagctt
    12181 tggaattttt acttttgaag ctttttttcc ttatttgctt tttcaaattc tttttgataa
    12241 gcatcgcgtg cttgtttgaa catcatcaat tgataaatat agctggcagt agccatatca
    12301 aaatcccatt tatcgataaa ttcatcgaat gaaatataat cagtcatgtt cgcttggcgg
    12361 taagcaatat acacagcctt tgcaccttga ataacagaaa tatccatgga tccttttccc
    12421 acagtcattt ttgcaaactc gtctgtgtta aaatctctat tgatcatcaa taatttcttg
    12481 atattcagtt taggttctaa attcaaaatt gttccatcgt ttagttcaat ttttgagtaa
    12541 tcttcgttca tttcgctacc tccgtttttt ttactgtgat tgagtggccg tagttgtcac
    12601 aactgaagtt tttttaatca catcagcaga tagattcgtc atccattgat ctgttaagtc
    12661 ttcttcaagt tctgcaacaa ttgcttcatg ataaaattta ccaaattcat cttgcataac
    12721 ttttgtttct agttctaacg cagctacttc atccgcacca ttttcaatag agaatgttaa
    12781 tcctgtattc gaagtgcatg ctaacatacc aactaacttt ctattttctt cgaagtcatc
    12841 cacgatctct gcagcaagtg agaaatcttc gcctacggaa tcaggaccgt aagagtaaat
    12901 gcctggttta atacgtccat cttgtttcaa cccattgaaa cgtcgataaa cttccatcgg
    12961 tacatgtgca gtaattgtta ccgtcatatt gattggttta gattttgatt ttacttctgt
    13021 cgctccacat tttttaacca ccgtttgcat ttctgtttcg ccatctaatt gtccgttaca
    13081 attcgttgcg attgcatttc ctgcgttctt aaaattaaaa gcaattcgtt tgatacttac
    13141 gttatcgaac gttgttacta cagtttttgt tttagccatt gttgttcccc ctatttattt
    13201 aatttatcga attgacgaat cagaagttct gtaattggat caagtgcaag acctaatcct
    13261 cttctcataa attcgtccgg ctgatttctt ttagaagtac ctatccccaa atcaggatat
    13321 tttaaatact caaattttct tgtaggtcta atgatgaaac ccaaattaat gtattgagtc
    13381 ttaagtggac gactattttt tgcgtgttgg tgccctcttc ttaaatctgc ttcagaaaca
    13441 ggaatttttt ctgtaatcct atccactgca atagccgaac cttttgattt caatgcttcg
    13501 ttaatcagtc gttcgctctc gcttgaatag cgttccatcc gcacaagaag ttcatcatgt
    13561 ccatttattt ttagctccca actattttta gccatgacaa tcactcttca ataatcgtct
    13621 aaacgtaaat accaattgat cgatatagcg atcttggttc tctagtttta aatgattggg
    13681 atccattctc tgaaaacgaa tcgaacgatt ttgaatcaat gaaataatat ctagtgagtc
    13741 tcctgttaaa tcttctctat tttctgaata gaaagttaga tatagatttt gacccacgct
    13801 atattttggc tcagtgatca tttctatttc tcctgtttcg agaatgaagt aattaaaatc
    13861 atcaggtagc tcatcctcgc ctacggagtc ttgaaagagt ttgaggccaa aatgctcttc
    13921 taaggaagtt ttgatagcag aaatttgctt atttaaacgt tctttttctt tagaattatc
    13981 aatcaccata ttcacccaca ctttcaagat aaaaatagat ataaaaatta tcgtaatcgg
    14041 catagataac gttgtaacgc atactatcga ttacgataaa atattgatct ttattaaatt
    14101 tcttggcgat tggatgaaat ggagtcttta ctttcttagt taatttcgat cccatcgcat
    14161 ccatagctgt tatatcacta tctctcatgg aaagatttct aaattttaaa gaagtgattt
    14221 ctgtatcttc tacaccaatc ttttttccta gttcatttct tttggtagtt tgcgtcaaaa
    14281 tctttaacca accatcgttg aatgtttctt cgagtctacg attattcgcc attcacatca
    14341 cctgcaatat attcttgtag cgcataatgt tgaatgaaac ctaataactc actagcgaaa
    14401 ttttgttcaa actcatctaa agcacgattc cagtcgtatc tacatctttc gattagcaat
    14461 ccgtattcta agctttcagg agaaaaagaa agtgttgtac tcactttact ttgaagataa
    14521 acagcatttt tagctatcat ctttttaatt gactcatctt cttcgttcca ggtaacgtaa
    14581 atattatcct tcacagctat tagcaattct tcagtcactt gttcaggcgt catctaacca
    14641 ccgccttaat tgctttaaca tatgcgtaag agcatttttt cttgtttaca aatgataaat
    14701 cttcatcaaa aggcgtagaa gtcacgtatc tccctttgaa aaataaatct tcatcgtttg
    14761 ttgttactcc agcattgtgt aagattttta cttctttaac tttttctatt ggatcagtag
    14821 caaaacaaaa gtctaattcc tcgtgaactt taggaccaat attgaaatac atcatgttcc
    14881 aaagctgtgc ccacatctcg gctgtccaga tttgtatatt tgttttttgc cctctaaggt
    14941 agcgatatag ccgattagaa tccagataaa cctttttcca ataattcgct ttaggacggt
    15001 taataaccca ctgtgcgcct cctgaattag tgtttatagt ttccaaagat tctactgtaa
    15061 catttacaat gtttgccata tcttttagaa tattttctcc gttttcacag cttctaatat
    15121 aatcaagact tagataacta cagcagtcgc tacaatacca aacatcatct ttagaaggca
    15181 atttgcgcaa attaattctt ttattgaaaa tgacatccga atcgatatag aaatatcggt
    15241 cgtcctcacg cgaatgatct tcttctaaat atttccacca taaatatggt ttaatcgaag
    15301 gaatatactc tttgtcgtcc cgcagatcat cgtacacatg aacttcaaca ccatattcct
    15361 tctcaaaaaa aataggaatc tgatcatcgt gtctgctgaa aagcaatacg atatctttga
    15421 ttcctagttt cttcagatta gttaaacaaa cttcaagctc ccatttaaac cgattgattg
    15481 ccggctgaca aagaatatac ttcattctga tcacctacgc ttgtgttgta gttgttgtgg
    15541 ttgttggttt tgtagttgta gtagtagttc ccaaagcgct aatatctaat acaatgaaac
    15601 tatcgttacg tttaggttga ccgtttgcat attgtttagc tagataaatg cgttcgtctt
    15661 caacaaaatg gtattcatct gaagcttcaa tttttagtgt agatcctaca cccatgaagt
    15721 aatctgaggc taccccaata actgcttttc cttctggcac agccgttgac tgcaaatctg
    15781 aaactggtac tggcaatact tgtacgtatt ctccattagc agttagtaca gtcttagctg
    15841 ggaatacttt agaccagtaa tcagttggat tcacaattag gaccacatca gaaggattca
    15901 cattacgata aatcggatca ttcacacctt cgatattgaa ttttgatagt cgcgccatca
    15961 aaccgcccat agttacagca tctaaagctg taataggttc tgcttttttt tcagcatatt
    16021 ctccgctagt ttgtttgctc atgtcacgca tcattccgac tggcatatct ttaccagtac
    16081 catcaacaat tgcttgttct aatgcaattc tcaatgattc tactaaaaca gtacggacat
    16141 aacgatctaa ccatactgga cctaaatcaa gcattgcctt acatacagga atataacctg
    16201 atagcttgaa ctgcttcatg ttaattacat caaagccatt atctaaaact tttttaacag
    16261 cttcgcaaag tttaccccac catgctggat tgactccacg tgacacaatc cattctgtta
    16321 caccagttgt gttaacaaaa gtaatttttt gcaatagtgg atgagattgt tctaaatctt
    16381 caaatacacg ttcaaataca gtagctggca ctaattcttc gacccctgca aaaccttcgt
    16441 ttttcactac ttcgttatag aattttgttt cttgtgtagt taatacacgc tgaccacggt
    16501 tcattaatac taattgatct tgattttttg ctgttgcttc ttctaaaatt ttatcctgaa
    16561 tttccttaga taagcttacc atagctgcgc taaaagattc ttcgttacca tctttaaaag
    16621 ctttcatcaa ttggtcgctt gcagctgtta caccttttaa atttttaact gtcattattt
    16681 tacatctcct tgtccaaatg ttttatttaa tgctgctgta aatgcagcaa ttttttctgc
    16741 tcttttttct ttaacgtcat tcaaaatttc ttcaacgctt tgttcttttt tagcttcagt
    16801 acctgagcta ttttctgcat cgataatttc atcgaccaat ccataactca aagctgtttc
    16861 tgcatccata aacgattctt tttcaagaag ttcttgcaat gcttcatctg tgccattgaa
    16921 tcgtgtttta tatgaagcct ttaccgattt atcaattgat tccagttggt cagcaatcgt
    16981 acggaagtca tcgacatttc cttctccgta tgtggaagcg cggtgaatca tcaattgtgc
    17041 attgttgtag atttttatag tatcgccagc cattgcgata attgaagcag cactagcggc
    17101 taagccgtta atcacaacgt taacttttgc tttatttgac ttaagtaagt tcccaatagc
    17161 aatcccttga aatacgtctc caccgtttga attaattact acttcaattt cttcttgatc
    17221 acctagacta tccaaaatat ttttgattcc cttgtcagta ttcccttcaa agaaccaact
    17281 agaaccaata aatccctgaa taaaaatttg cggtactgcg ccttcattct ttactgctag
    17341 aaatgttttc attgtcgtca ttcgcctcac ctcctttcga tacttgttga ttgtttttag
    17401 ttataaatat ttcatctgcc atcgccttat cagagcgatc atttccaacg cgttctcttc
    17461 cttcgttgat tgtaaatact ccatttctaa tgcctacatc aatagcgtca accaaatctt
    17521 tgaagctagt aatcttgatc atagttgtat ccacacgtac aaaattccct gacaagtatt
    17581 cttctacttc atagagacta gcgttaaacg catcctgaat aagttcagca atcggtatga
    17641 tttcgaacat taaaaaagcg tccacttgat ccgataaccc actcatgtct ccctttagta
    17701 ggtttttcgg aacgtgaaac gctgctgctg tcatctcaaa gatgtcgtct attaagtttt
    17761 ttatatctct tgaattgctt tggaagtttc cgctgaaatc ttctaatgtg tactcatttt
    17821 gtaattgaaa taccgcacct gcattatcag cttccataaa agccttaaat tgtgatgtca
    17881 tcattttatt gatttgatct tgtgttgtat tgtcttgcgg tcggaataaa ttccctttca
    17941 gtacgtatct acgagcgtta gagcgcttgt aaacattcat ggcactagaa atgagtttcc
    18001 catacgcttg ataatacgca tcgactagtt gcctaatttg ttgatctgcg tattttatat
    18061 agataacatc actttctaga aattctctat caaggactat gttgttaatt tgcacttgag
    18121 aaaacacatc atctttcaat gcatattctg tgacatccca actatccgca ataaatattt
    18181 cgctagaatt attagacgga gaaacgatca atacttcatt gtagaatatt aatctcctga
    18241 tcagtttttt tctaaattct gttgcattat ttttcttatt aggagctaca ttcagcctat
    18301 agtaaagatc attcttttta ttttttccat cttcatatga cttgaattcc gctttactca
    18361 tcgcatttgc aatcaaatca atacaagttt caatcgcaaa ttttcgatac acaaaatcaa
    18421 cttgcaattt acaaaagtat tcttctaaag gaaccgttgc tttttttgtg aagtatccta
    18481 ccgccttttg aaaaatcccc actttctcac ctcctttcaa gttagaatac tagaggagta
    18541 aatccagttc ctgtattttc tactgagcta tttgtgactg ttacaggagc agaatcataa
    18601 atatcatcta aaaaattcaa accatgaagg aatgaaaaaa agccatccgt ttttctagtt
    18661 tcaggttcta ttttttcata gcgtatattt ccattagaaa tatgctcttc atatacattc
    18721 atgcaatacc aacgcataat cgcatcgtca ccaaaaaata aacgttgatt aataaaaagg
    18781 tcatcaacca gatcttttaa cataccatgt gtaacagatc cgcttcgaac aatttccaca
    18841 gtaaaacctg cttcttctaa agcgggcttc aatatttttg cacggtacat atccatagcg
    18901 atttttttaa tataatattt attactcatt tcaagaaacc aacctacaat ataatcagct
    18961 tctatatttt ttccatgaac gatctgtgat tttccttgat ctatagaaat atctataacc
    19021 tctcgtttga tgttttgtaa tcgaagggct gattcgtgga taaaagtatg ttgtgtaaaa
    19081 taaacatctt tatcgtattt tcctagcaac ccaacgctgg caaaatctcg tctatcagca
    19141 aaatcgactg ttcctatcac ttcatccatt ttttcaggaa attctttttc tttcgtatgc
    19201 agaacatcat catatgaagc aacagcaaat cgtgtatctt ccataggtct gttcattcgt
    19261 ttggtcatga acgtaagtct taaaccagca ttacgttgca tttgagagta ttcttgaaac
    19321 attttccgtt ttaaatctgc attgtaatta atagttggac aagctttttc ccacatgtcg
    19381 ggatcatcaa cttcattatc gttatccaag cgacaaataa atggaaacaa actagaaaat
    19441 tctgctccat ccttgtcaat tccaagttct ccagaaagaa tcatttttga ttcttctata
    19501 atgtcatcaa gcggaccacc acgaacatga ccattagttg tatcataaaa ttctctataa
    19561 tctcgaattt taccaccacc agaagtagcc acatttatca ttgaataatc ttcattttcg
    19621 tgaatttcat caaagcggtt tgcacctggt cgcttcccat cttttgttct agcatttgcc
    19681 gtgttataac gaagtttgct gtttgtagcg atattttgaa taacttcctt cgtagcttta
    19741 aatacttttt tatctaaatc aggatgatct ttaattactt taaatacatc atcaaaacta
    19801 gtctttgctt ggctttcatt attggcatag atatcaatat cataattttt aataccgtgt
    19861 ttagcggtta gtagaaagaa gttgttccaa gaagcaaaac cagttttacc attaccacgt
    19921 cccattaatg aaagatatct attgaacact agtgttttat cttttttcca tcgaacacca
    19981 taaataaaac attgtagaaa tttttcccac ggaattaatt cgaatggaaa gtattgtgct
    20041 ggtatattga ttgaatcctc taccatctgc ttatcgaagt aaatatcttc tctagtaaag
    20101 actctttctt ctagataatt ttttagcaat aattgctctt tgcatacctt gatagtgcct
    20161 tcttctatag ctttgaacca attttcaata tgcttataac tcaggaattg attcatttgc
    20221 ttcacctacc aattcaggag taatggcaag tttatccaac atcaatccca tttgtttgtt
    20281 gacagaaaca agcaacgcta ctgattcatt ctttttacca ttctccagtc taatgccgtt
    20341 ctcggatata tcttcttcca gtgatatcgc cgtttcccat aaactgatat aacgatcaac
    20401 attatctaag aatggctcaa tatttgtttt ctgactttcc aattggctta ttaaagagcg
    20461 gcgtaatttt tctctgtagc gattttgaga caattcgttt ttaaacattt tagccctcct
    20521 ttcatgataa agttcgaaaa aatctctttt cctgacagcc ccctccgttt catcaccccc
    20581 aaaaaatttg cgatttattt taaggggggg ttatctcacc atcggaatga aagcttcagc
    20641 gaagtcaatg taataattaa tctcttcaat actatatcca aaaacatttt ttattctttc
    20701 gacgttatta tctttattca acgcttctct tacttgattc actttgtatt tactacaaca
    20761 gttatctgat aacagatccc taatacctac atagcgaacg tatatcaaac gtttaattaa
    20821 tccctgagta taagatgaat actcttcaat cttttctgta tcatactctc tgccattatc
    20881 attgatgatc atgcacttac cacctttcac ttgcatcgaa gttagcaaag ctttctatct
    20941 tcttctcttg tttatccaat gctgtaagat atctgccatg aacttcatta tgatgttcaa
    21001 cacataaaca aataagatta tctaaatcta aagctaagtc aggtctatcc ttgacttcct
    21061 ttatatgatg aacgttctct actctatgat acttacctag tcttctacac tcttggcatt
    21121 catagtgatc tcgtttcatc gctttctctc taagcctgcg ccatttagga gactgataga
    21181 acttaaccaa acgatcttct cttatcaact gtaatagcca tctatagaat tcctcgttca
    21241 tgtcccgtct cctttcacaa tcttatttaa tgcttagcta ttcttttgcc atacaatgga
    21301 ataacttcat tgctttcctt tcgtttatat gtatcgctct ttattggtct tctatacttt
    21361 cgtactatct ctccgttacc attttgcaca gtgattactt catacttctg ttctaagtat
    21421 tgtggtctat acattgttgt tacctccttt gtgcaaaata aaaagaccac tcaacgagtg
    21481 atcctaacat cttttatttg cataacgtaa taccttaact cggctaatgc gttatcaata
    21541 ttgtcagata gttctttttt gggagctttt atattttgtt ttgctacagt ttccaacatc
    21601 aatatagcat atccatcaaa aaagaaacta ttttcattct ttttctccgt tcgtactaat
    21661 tttgtttcat tttgaatcaa tttcaactca tcatatactt ctttccactg gtcataagct
    21721 ttatttagtt ccttatttat caaataagaa tttgcatttt ctaatttctg tataaatcca
    21781 ttaatttgat tttcaatatc tttttttgtg aaaacttttt gtcttaaata cattttgtct
    21841 tccatgcact ctcacccctt tcgtaatatt tttattatat cattttttac tatgtacaaa
    21901 taggaacagc ttacatctac aaacaacagt ttttttaagt tgagtaaata ctcaataaaa
    21961 ccgaaagagt tgcaattaat agacagcaac acatgaacta actgtaggag ctgaccccca
    22021 catcctttag tttatttgct gctgtctatc gaagcttaat taaacgatga gggagatttc
    22081 ctcccttaca ttttattttg tcttagacct atcactaatc tttcgacact accataatat
    22141 cactggtaaa tagctaaaaa ccgccatcat tccgccaaaa aaccgccaaa ttatttataa
    22201 gcaattattc ttccgtgttt atatgcttct gcaaactcta ttagagcttc cgacttcatc
    22261 cgttgtatac ttctttctga ataacccact tcacggctaa tcctgtagtt tgagaagcta
    22321 tctggcacac agaagctgta gtagagtatc tggcgactaa ttagactaag agccatcaaa
    22381 gccgctagaa tcgcatctct ctccgcttct atatccatca tctgaatgat cgcgtcttct
    22441 gccttattgc cgtgctttgg tgccttcggc atatccgtaa taatcggcga cttaatatct
    22501 atcaaagagc gacctgccat ccgctccaag cgccgaaagt tcttcagcac atctctcgca
    22561 ttacatcttg tctgtttgaa atctacctct cgtaacaatt gcatcaagtc aaaccgctcc
    22621 tttatgtgat ataataaact tgtggaattt attagatcag tcggagcgat ccggcttttt
    22681 tatttgtcat tgattagttc aatatccacc aatctcacca ctgctaaatt atctttgctt
    22741 ttcgctaacc acttgtcgca ttccatcgtg ttttcaatgc gaatgatcgc tgagtgatta
    22801 tagagatgct ctacatatcc acgaaacgga tagatgaacc cttctgcttc gcagcgaacc
    22861 atgtcaccga ctttgaattt tggtttctta cgtgttttag ggttctttgt cggcatatct
    22921 agcattaaac ctccgatacc gtgactgcta gagtagaatc cgtcttttag tttcattact
    22981 ctacctcctc gtgatcgata gtgaccagtt catatacttg cgctaatcca ccaagtcgtc
    23041 gtgaaacttg gttagcttct tcgagattat caaaccatct tgcactttgg agtatgtcta
    23101 caatggataa tgtgttagcc cctatagaac gttcatcact tctgtaaaat tgatttccaa
    23161 actttactac ataaatcttc attctgtatc ctcccattta atatctagta tcgaaattcc
    23221 aaacttacga atagcctcac tcgcatcagc aacacactga cttgccactt tgtatgcttc
    23281 ttctatagaa attccgtatt ctttttcaaa cttcgccttc agtgcattaa gttcttgttt
    23341 tcttagtttt gttactctgc ggtgtctgtt gttcattgtc aatcaactcc ctaatctgaa
    23401 agtgtcgttt atacttgatc gaaattcttt caagtggttc tctaccacag aatcagtcac
    23461 gttaaaacga tcaattaata caggagctgc catatctttc aaataacttt gtctgataac
    23521 tatttcagta ccatcagaaa gtttgaattt aactttgcga ccattaataa ttgactgaac
    23581 gtctgcttcg cttagtgcta tttcgtattt cattctgctt cctcctgttt tattttcacc
    23641 atttctttgt tgaaaacccg caacgtctat actgtttaat tcgtttctta ggtctttcta
    23701 gatcaaccag aataaatctg tcggatatat gataatcttc tattacagcc gtatacattg
    23761 gattcgaaac cgagtaccat gatctttttt tatcaacctc atccgcatca tctcttgtaa
    23821 tttctatcat gttagcagac attagatagc tctcttcttc tgcctcgaat gggcaggaat
    23881 attcatccca gcttcgagga aacctggcca aatctctttt taaataaact tgaacattca
    23941 ttccgcttcc tcctcaatcg tccaagcatt tgtaaatttc tctaagctta ttagttcatc
    24001 ttcatttaaa tatccgtaac catataagga ttctaaaagg tcttcttttg aatagcctct
    24061 aaaatcaagt ctgagaccgc ttaggatgta tacaaaggtt ttatttccat aaaacttgat
    24121 tgtgtatgct ttcatttcta ttcctcttgt tctaatcctt ctatcactgg cacagcaaat
    24181 ggccaatatc tttcatcaat tgcttttatt tctgattccg taaatttcat atcatcaaaa
    24241 tcattgttgt ctgcaattgt tatatttcct cgatcatctt tcattagata cgtctctaaa
    24301 tccaaatgat taaaatacac aactggtaac ttcacataat acaacggttc tttctcaacc
    24361 tcgtaaccat acagcaacgc atttattgct ttttctttat taagataaag gctatcttca
    24421 acaagccaat ctagtaactc tcttgttgtg gaagaatttt cgcttttacc aagttcatag
    24481 tccacgccat aaccccaacc tgcacgtgca ataagagaaa tggcataaaa cttgtcacgt
    24541 tctgctataa ctctttttgc ccaatcatca aaaaaactta ggcataactg gtttctgcga
    24601 ttcgtctagt tttaacaccg tattaaccat atgaacgact tgagaataag ccatcaccat
    24661 gccctcatag taatttttgc tttctggatg cgtcagggct ttgtgctgtt tttctagtga
    24721 aattctcttt agttcattaa tcaattcctg tttattttta ttcattgctg tcctccaagt
    24781 attcgtctaa tatctcttta tatttctcta caaatttgaa acgatcttga tgaagtttct
    24841 tcctccaatt cgtttgttta tcaagctcgc gcatctgctc aaagcctttt tgaatttcgt
    24901 tgtaataaaa ttcaatgttt gctgttgctt tccaatgcct gctacttcgc actcctgctc
    24961 ctgtttcagc catttctaac ttaactaatt ccgctcgttc ttttgatttt ttatctttct
    25021 gaatcttcat catgattttc ttgaggatga tatcactgta ttgtgtaatg agatccatta
    25081 tttctcctcc acatgtttaa attgacgacc tttcgaatca acgttctcgc gtttagctct
    25141 atcccagata atgtttttgc ttagtccagt aatttcagat aactgttcag cagtacctgt
    25201 tactagaatt cggtcgccat gccagattgc aatttttctc ggcgttttcc gtttaggctt
    25261 ttcagtccac attgatttac cgagcttttg gacttctgca actatttctt tgtcttcttg
    25321 ccaagattct gacttggtta attcagcaat tcgtttcatt gctgctttct tatccacgtt
    25381 tattcctcca atctacgaat tacccttctt aaattctcta tgtgcaaatc gattgccttt
    25441 ctagccgttt cattgaccat cactgccttt gtccgttcca gatcgtcaat ttcacgctga
    25501 atgtttcgaa ttcgcatttg aatcacttct tctgttgtca tgatggacca cctcgttaaa
    25561 aacgctcttc cttgaacgta ttccgatatt ttttggctaa tatcaacggc acttgatatt
    25621 gatgacaaaa cagctttgcc ttgatcttaa agtcttttgt ctgcatccct ttaacatcta
    25681 cgactttgac aagtttgccg tttttataaa atgtgaagtc gggaatatac tcgatcttgc
    25741 gatacttctt tccttctagt tcaaatttcg gcatcagctc aaatttttcc tgaagtttta
    25801 ctttccagcc gttcgcttcc gcttgccaca aggctagatc gtaatactct gcttctgcga
    25861 tagaatcgaa cttgatacct cgatgaacag tctttttatt acggtatttg ttcatgcgat
    25921 actacctttc actggtttta tgcgcttgtc tgctgtttgt tggaatttca gcgcataacc
    25981 ttctgaattt ttaaatatcc tagaaacaat tctttcgccg taggcttctc ttagctcagg
    26041 accagataag tttgttgtga tgatcgttgc tttgttctgt ctggcttcta agagcgtgtt
    26101 taacgtgttg tttgtaaact gcctactatt tgataccccg ctacctagtt cagctccaat
    26161 atcgtcaaaa accaccaaat cagttgtttt gatatcggct ataagcgatc cttcaatttc
    26221 ttttctcagt tcagcattgt tataagagaa ctttatttgc tctaataatt cttgatagct
    26281 tataaaaagt attttcttgt cataatttga gcgctcaagt atttcccaag ctgtcgccat
    26341 tgacaagtgg ctttttccgc ttcctgattt ccctgataga atgaaatgtg caggatggtt
    26401 cagtaggaca tcatttacat agcttttagc tctttctaaa gcaattttcg tttcttggtc
    26461 cactacgtga taattctcca ttttgcattt aaacaaagtt ttatctgtta ataccgaacc
    26521 attttgaaaa aaactcaacg ctcgtgcttt taagctgtcg ttatatatcc gttcggtctg
    26581 tatatcctct ttcacacgta acgctttata accacaactc atgcatgttg gtttacaacg
    26641 ttctgacccg tccttatttt tccctcgcca actatacaaa ggttcgctgc actctgggca
    26701 ttttccactt tgtactaaaa ctcttcttat tagcttttcc atagtacttg ctaggctttc
    26761 catcagttgt atctcctttg ttaaattggc aagtcgtcat attcactagg attgctgtac
    26821 tgtagttttt gactttgctt tttatgatta ttcttgtctg ctttgatttc gaatttgagc
    26881 ttctcaaatt tttctctcaa tttcttagca cttctaatat ttccaaacca aaattcattt
    26941 gtaggtagcc aattgatcac atactcaatc gcttctatag acgctttatc tctttcttcc
    27001 atcaacctaa ttgcgtctgc ccatttttcg atatctactt tattcatttc ttttggaaaa
    27061 tcttcagtta aattactttg caacttttta gcaaggcgta agtgttcgtc agaatactta
    27121 cctttctttt cttctttatc tatatctata tctatatctt tctctaactc tatctctagg
    27181 cgaccttttc cagacaactt ctggacattg tcctcctttg ctctttggat tcgtttttgc
    27241 ctagcgtatt cagtctctga tcctactaat tcacttagct gatttagata tatctctccg
    27301 ctgtccagta tttttattag tccgattttg ttgaatagat ccatagcgac tttcactgtg
    27361 tccgtatttg aatttgttag ttttgctaga gattcgggat cgtaaggtat catcagatta
    27421 cctacatttc taactagtat tccttctgtc tttagagatt taagacagag tttcagataa
    27481 aataaacaat attctttacc attcggttgt tcttccaacc attcgatggt atcttcttcg
    27541 aaaaaatctt cttttaattt aagccagtaa tagcgtttct tttgtttgtc tgacacttca
    27601 ataccacctt ttccttatcc tccgatattt aactttttga ttgtctcctg gtttaacttg
    27661 atccctttga tttgatattt atttttgaaa ttgatcacac ctatcttgtg tttctccgtg
    27721 tgatgaatcc tgcagagtgc tgcaaatgtg tactctgaat gatcaacttc tttgcgcttt
    27781 cgtcttccta gcgctttgtc aaagtgatcg atgtcagctc ctgttttgcc acagatgcag
    27841 cagactcttt ttgtgatgca tttgtagaag taatactctt gattcgctgg taaaatctca
    27901 tagccttctt tgaaaggaat atgatgttca aagatgaaat ctaagataat atttgctaag
    27961 acgttggcat cactcacagt tgtattagat tcatctttca ggcttatttt gcgccctgtg
    28021 acaccttcga aacggaagta gaagaattcc ttccagaagt ccgttggcat gcctgtatcg
    28081 ataaaaatat cgcctatcag cgcatagatg aagtttcgtt gctgtgcggt gaaccgacgt
    28141 ggatcaataa aacgaatttc aatgattcga tcgccatcat agccgtcata catcgttttc
    28201 agccgttcga tatttacttc ttcgttgatt gttgcatcaa tgtcgttacc tttaaatttc
    28261 tttagtaccg ccgagtatga atctattagt ggtttaaaca ctcatatcac ttctcttttg
    28321 tttcttctct gtactgatct tcaagccaat taacgcctcg ttttagaatg cccaagtctc
    28381 tcttggtcca tttactgtca tcagcggtta tagaagccgc atcagtcaat gcaacaattg
    28441 cttcatcaat cgatttttcg tacttgttag caaccagttg taaagcatct aagaatagct
    28501 ttttgcttct ttgagtagct ggttcaagca tcgaaacatc ttctggcata tcttcgccag
    28561 caaatatata tagccctagc ccaaacatcg ctagattttt tacaagacag cgcatgattg
    28621 ttttattgat atcaaacatc gttgctgctt caactcgctt ttcgattttt ccaacaatct
    28681 cttttttctt cgtttcgtta ttccactgat aatcattgac ttcgtaggta tatggctcat
    28741 ctttcattgc cttgtttgca ccatccatga ctggtaacca catgtcacgc tttactccgt
    28801 tgactgtgat actggtaaaa accatatagc ctgttttttc atcaaagagg tatggacgat
    28861 gcgtttctgg atcacgatag atttcgtagt ctacttcttc gcagattttg ctgacttctg
    28921 cccacgccca tgcccaggac agataagtta gtttgtttct tttttcgaca acatcattga
    28981 cggttatctt gtaaagacta ttgaataatt tgttatcgtt gcgtttcgtt ccttcactca
    29041 tcaaattctg cctccatttc agcaatgtac ttcttgcctg gtccgtaata agagatatca
    29101 atcaagttat ctctgtcgta ctcctctagc gcatcaatca agccatcttc gatgacatag
    29161 atgtattcag gttttctgga ccgcttcgat agatgaataa gatagacatg atcctaaata
    29221 ctcacaaaat ttcccaaatc gtcttgatca catgctagtt cttcatccgt caaaagattg
    29281 cgtctgattt ttcgattgct tgtttccttg atattcgatt tgccccaact aggatcagtc
    29341 aaatattgat ctagagtgga aagttctttt ttcatgtggt aacatctcct tagatgtatt
    29401 ttctttgtga ctcattgctt tggtcggctg agtcactttt ttatttgttg ccatgctttt
    29461 tgcttatcaa tatgttgttg gcttaggatg cttggtttat tgtgtctcca ccagcgatta
    29521 gcaattaccg tccctattct tagcgcttca gccctattca ttttcatcac cgaaaagtct
    29581 ttgttgtctg ttcagttgat cgatttccat gcggatcgca gtttctggta accacatttc
    29641 aataaatgaa acagcatcat cgaatctctt acgaggtaac tcgccatatc ttgggattga
    29701 aaaggtacgt ttaaattcag accaaaattt tgaaaatact tttttgctga tttcttcata
    29761 agctcggctt tcttttcccc ctagaacttc cataactttc atatttcctt tttgcttaat
    29821 ttcaaactct tgttgtccgc taattcgcat agtatcttta agcatggaaa catctttttt
    29881 aacatctttc atttcttcta attgatagat catcatgtct tcaattgttt gaggaacagt
    29941 attcttccga ataacatctt ccatttcgtt gaaagcttca ataaatttta gtttgaaatt
    30001 tattgcttta cttccagtga atcccatagc tagcaaggaa aatccgtctc tattcatgaa
    30061 ataaactctc cgacttcttc cgtatgagtc tggctcgttc ccttccacaa acatctgtcc
    30121 aaaattggac ccatcttcaa cattggccga attttcgacc gatcttttta ttgattcaat
    30181 tgcttctagt acatgcttat gtttcttttt gaaactttct gccacttgta agctcgtagt
    30241 tacagcttct ttatttttca aaattactaa ttcttgcatt atttcttctc tcctttttgg
    30301 tataattttc gttagaaagt gaggtgattc tatgaggaaa aagctcaatt acattcttac
    30361 tgcgacttta accatatata taattctgtt tattacctta tctttcctgt cttcaattaa
    30421 aaaaattcct tttattacat tgaataaaaa tagtattttg aaggagttca ataacattga
    30481 ctacatcgca tttctaaaac ttttttcagt ctgtgtgcta atatcatgtg taattatttt
    30541 tattgttgct aaaacatgtt ggacaatgtt aaataaaaac caacgcgatg ttgaaaatat
    30601 tgctatattt ttaattaaga ttacttcctc aatatcaatt atcattccga tgactgtaac
    30661 tttttcaaaa gaacagttta atgtagcggc tacttatctt tcatttatag cgctattttc
    30721 ttttgttctt cctaaaagaa ataagagcaa ctttgacaac aaggagctgg atgaagtacg
    30781 caatagcagc ccaaaggaac aaaaataaaa aaatcatatt ttagtcagtc cctcccgact
    30841 ggcttttttc gctctgtgct cagcttcatc aagccccata aaaatccaaa ccatgtaaac
    30901 gattgtccct atcaacgctt gtttgcttcc ccaaagtcct aaagcgtaga tgattagtgg
    30961 tgcgctgaat actagtgctc tattaaattt tcccatccgc ttgcctcctt aagatttccg
    31021 aaaaatttgt ttctaaaaat tcaagtgttt tacttcttaa aaatagatat gtgtctcttc
    31081 cttcaactgg ataatagaca aatccatttt tgtttttttc gatatcgata atatttctat
    31141 atcttgggtt ctttaaaact ctagaagtaa accaatcata ttttctgtta atccgttcta
    31201 gtacttctgg caacgtcatc catctaccag tatcatcagc tttttttaac tcctcataat
    31261 ccacttggga gataattaca tagccttctg gaattgggat ttttgcttct agatattgca
    31321 ttagctgttc ctccctttac aattcgtaca tagtgataat cgaatctata attctatttg
    31381 cttctgcaga agtcttttta ccgtttaaaa ttaaagataa gtagcttttg ctaataccga
    31441 atctttcagc aagcatggtg taagttaaga attttgaact ttcgacatat tctttgattt
    31501 tttctctatc tcgttgagtg atttctgcaa tatcagtcat tattcaacct cctttctaac
    31561 caatctcctc taaatccatt tgaggataat atctttcttt ttttagtaat tcgtagataa
    31621 atagacgccc tttctgtgtc catttggtat tcattacaat tttagtgcca ccatcggctt
    31681 tcggaatctc agttgtatga gattttgtgt atccttggtt catgtgtttt ttgcacaata
    31741 accattggtt accgactttt ttctgaatac ctagtttatg aagtaattta ttcatctgtt
    31801 gtggagacat cccataatct gctgcaatct gactaattgt tactgaatct gtagaagata
    31861 atatgctatc taaataggag attttaggtt cgtactctgc aatcttttgt tctgcgatta
    31921 atcttccagt tctttcttct tttagttgag ttgctaattg aatgattgta tctggattaa
    31981 gcaaagcttc ttctactttt tctggagtta gataacctcc atgttttcta attgctggca
    32041 acacttcact tgttacccaa cgtttaaatt ttttggcaga gggaagtttt gattttaaga
    32101 ttaaactgta caaaccagat tcgttgatga ttgtcatctc tcttgattga cctgaggtcg
    32161 tgattcgcga ccccatctta tcttccaaat ctacatgccg cgacaaagca tctttagtgt
    32221 ttgaataacc caaaacactc gcaacgtctt tgcctacaaa atatggttca tcatttacta
    32281 aaattgtccg aacttcgttt tgttcgaaat taaaaatttg cggtgtgttc atatttctca
    32341 ttcctttctt tgatataatt ttcttatcag taagtggtct actgaaataa tgcataaggt
    32401 ggtgaataag tatgaataaa aaaatcgctg cggatttagt tgttgcatgg ctaaatcacg
    32461 aatcacaagt atctactaaa ggcgaatcaa tttcgccaaa agaaattgct caagcttatt
    32521 tagatattca ttatgctgtt atctatggtc agcttccaga agaccgtaaa aacgatgact
    32581 aaacgtgagc taaaatctct gctatggctg caaccatggc agagtcttct ttatctaccg
    32641 cgtgttccat cgccactttt gcttgtttca gtatgtctaa tttcaaatct tcgatttttg
    32701 ccgagactgt tttttccata ttcttctctc ctttctttta tattcgtaaa caaatttaac
    32761 aacttttttc taaattcaat tgacaaaaca tagagtttta ttctatactt tgtacatagt
    32821 taaataagac atataaacat tgattttaaa agctttcttg gcggttggcg tttaataatc
    32881 aaaagtgttt tttgttgtct ttttagttgt taaacttgtt tacaagaata agtatagagt
    32941 tttagctcta atttgtcaac agataaatag agtttaattc tatatttttt cttgtcagtc
    33001 tagaaaggtt gacatatcaa tgaatccata cgaaaaaata aaagaattaa caaagcaaaa
    33061 cggaatatct gtaagagaat tagaaaaaag attgggatat tcaaatggat atttcagtaa
    33121 atggaaatca gtatcaccta actccgaagg tttggcaaaa gtatcagatt actttggagt
    33181 ctctgtagac taccttctag gaagggagaa aaaagagacc cctaaacatg tggatttatc
    33241 agaagacgat actgtttttt cttttgatgg gaaagaaata tctaaggaga caatgcgtaa
    33301 agcgattgca attgctaaag ctttagagga aaatgaatag ttggagtgat ggtttgcatg
    33361 tatttaaagt tgaaagaaat gctgagtggg tataatttaa aattgatcta tatggaaatg
    33421 gaagaaccag gtttttatta cccaaaaccc agaatcattt ttttgaatga aaatctatac
    33481 ggtgaaactg cagaagcctt tcatttatct catgaacttg cacatttcag cgcctctcat
    33541 tttgaatttt cagttttgta cgatacttct acaacttttc actcaaaatt tgaaacagaa
    33601 gcagataaaa tagctattct aattttatta aatatctata ttgagaacga actgactgat
    33661 gaatctcagt ttaatctcga aaaatttatg gaatattatt ctattcagaa taagctcaga
    33721 tacacttgtt atgctgtctg ccaatgctat tttaagaaaa aatattctta cgcaaggcaa
    33781 tatgtatgaa tacatcaaga attattaaaa aaaaaccgat ttcagcaaaa cattaaaaaa
    33841 gcccgtgctg caacacggac tcatacctca tttctgagat cacaaatata ttataacaag
    33901 aagtgaggaa tatttaaatg gcaaaaaaag ttatgggtca agacggaaaa atgtataaag
    33961 ttagtaaacc tttttacaaa aaagtatggt tttgggtatt agcagtaatt ttaattataa
    34021 ttattggttc tgctttaaat ggtggttcag atagcaataa agcaagtgat aatggtggcg
    34081 aaaaagtaac taaatcttca acctctgctt catcttctaa agaagaaaaa agcgatactt
    34141 tctataagat tggtgacact gtaaaagttg gtgatgctga atatacacta aacagtgtag
    34201 aactaactga tgaaagaaat caatttgaag aaaatcaacc cgcacaagta gtaaaaatta
    34261 cttacactgt aaaaaacgat ggtgattctg atctccctgt aggaacagac gtggaagtat
    34321 acggaccaga tgacaagaaa tcagaaacat atgccaacga aaatactatg ggggctgttg
    34381 ctccaggaaa acaaatggat gtaactgctc atttcacgtt aaaccaaacg ggagaaatag
    34441 aaatccactt ctctcctcta gtatcatttg aaaaagcagc tatttttaaa gcaactgtat
    34501 aataaataaa aacacgcccc accgaccaaa gcgagcgtgt tctaaaaaaa acaaacctac
    34561 ataataggct tctttatagt gtctattgta tcaaagaaag tgagccgatt caatcatggc
    34621 aagatttgtg aaacgtggaa atagctggca atacgaaatt tcatacaaaa aagatgacgg
    34681 aaaatacacg aagataagaa aatcaggatt taagacaaaa ggcgaagcaa aagatgccgc
    34741 caacgaatta gaatataact tgaacaaagg ccttaaaggg gatcgcaaaa atctattatt
    34801 atcagattac tttgaggatt ggatgcaact ttataaagaa ggaacagtat ctcctatcac
    34861 ttatagaaaa tacgaagata cgttaatgaa cataaagaaa tatatgccag cggtattgat
    34921 ttctgattta gatagagttg gatatcaacg ctttttaaat aagtatgcga aagaccatgt
    34981 aaaatccacc gttattaagt ttaataacca tattagagca tcgttgaaag atgccgtaga
    35041 agaaggatta attccgtttg atccaactag aaaagcagta atcaaaggaa aagattcatt
    35101 gaagccaaaa gaagataaat atttagatta tgatcaattt aaatctttaa tgaaactcgt
    35161 agaagaaaac ctttctgcac agtactcttc tcctatgctc gtgttagttg ctggtgctac
    35221 tggaatgcga tttgctgaac ttctaggatt aacatgggaa gatatcgatt tcgaagatca
    35281 aatcatcact attaataaaa catggaatta taaattaaat gaatggggaa aaacaaaaaa
    35341 cgaaacttca aataggaaaa tttccattga taaacatacg attgatctct taaaaaagtt
    35401 taaaatcaat caaaaagaat tattcgagaa ttttgaaatc aaaaaccctc ataattttgt
    35461 ttttttcaac ttaaaaaatg gattagtttc atcaaacgcc gtcagcaaat atttgcgcaa
    35521 aaaattaaaa gaattaggga ttgaaaagca atttactttg catggactaa ggcatacaca
    35581 tgcatctatt ttactttatc aaggagtaaa tatacttagc gtatcgaaac gtttaggaca
    35641 tagcagttta gaaactacaa tgtctactta tcttcatatt gttcgagagc ttgaagatca
    35701 ggataaagaa aaaatcaata ctgtgttcga tagtttatat aaaaatgata actagtttgg
    35761 cacatttttg gcacaaatac aaaacaaacc cctgt
//
LOCUS       DAXLPC010000019        35236 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.019, whole genome shotgun sequence.
ACCESSION   DAXLPC010000019 DAXLPC010000000
VERSION     DAXLPC010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.019"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            80..1741
                     /locus_tag="ACF3UE_000916"
     CDS             80..1741
                     /locus_tag="ACF3UE_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3634369.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(1811..2158)
                     /locus_tag="ACF3UE_000917"
     CDS             complement(1811..2158)
                     /locus_tag="ACF3UE_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFD3634370.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2242..3183
                     /gene="opp3b"
                     /locus_tag="ACF3UE_000918"
     CDS             2242..3183
                     /gene="opp3b"
                     /locus_tag="ACF3UE_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFD3634371.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3184..4227
                     /locus_tag="ACF3UE_000919"
     CDS             3184..4227
                     /locus_tag="ACF3UE_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3634372.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4233..5303
                     /locus_tag="ACF3UE_000920"
     CDS             4233..5303
                     /locus_tag="ACF3UE_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634373.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5293..6246
                     /locus_tag="ACF3UE_000921"
     CDS             5293..6246
                     /locus_tag="ACF3UE_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634374.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6258..7268
                     /locus_tag="ACF3UE_000922"
     CDS             6258..7268
                     /locus_tag="ACF3UE_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFD3634375.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7553..8374)
                     /locus_tag="ACF3UE_000923"
     CDS             complement(7553..8374)
                     /locus_tag="ACF3UE_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFD3634376.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8471..8749)
                     /locus_tag="ACF3UE_000924"
     CDS             complement(8471..8749)
                     /locus_tag="ACF3UE_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634377.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9017..11026
                     /gene="metG"
                     /locus_tag="ACF3UE_000925"
     CDS             9017..11026
                     /gene="metG"
                     /locus_tag="ACF3UE_000925"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFD3634378.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11505..12092)
                     /locus_tag="ACF3UE_000926"
     CDS             complement(11505..12092)
                     /locus_tag="ACF3UE_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634379.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12267..13589
                     /locus_tag="ACF3UE_000927"
     CDS             12267..13589
                     /locus_tag="ACF3UE_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD3634380.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13744..14520
                     /locus_tag="ACF3UE_000928"
     CDS             13744..14520
                     /locus_tag="ACF3UE_000928"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFD3634381.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14513..15082
                     /gene="rnmV"
                     /locus_tag="ACF3UE_000929"
     CDS             14513..15082
                     /gene="rnmV"
                     /locus_tag="ACF3UE_000929"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFD3634382.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15075..15959
                     /gene="rsmA"
                     /locus_tag="ACF3UE_000930"
     CDS             15075..15959
                     /gene="rsmA"
                     /locus_tag="ACF3UE_000930"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFD3634383.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16410..17039
                     /locus_tag="ACF3UE_000931"
     CDS             16410..17039
                     /locus_tag="ACF3UE_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634384.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17163..18272)
                     /locus_tag="ACF3UE_000932"
     CDS             complement(17163..18272)
                     /locus_tag="ACF3UE_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634385.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18481..18903
                     /gene="mgsA"
                     /locus_tag="ACF3UE_000933"
     CDS             18481..18903
                     /gene="mgsA"
                     /locus_tag="ACF3UE_000933"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFD3634386.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      19090..19188
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            19226..19762
                     /locus_tag="ACF3UE_000934"
     CDS             19226..19762
                     /locus_tag="ACF3UE_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFD3634387.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(19802..21565)
                     /locus_tag="ACF3UE_000935"
     CDS             complement(19802..21565)
                     /locus_tag="ACF3UE_000935"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634388.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21568..23283)
                     /locus_tag="ACF3UE_000936"
     CDS             complement(21568..23283)
                     /locus_tag="ACF3UE_000936"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634389.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24062..24286)
                     /locus_tag="ACF3UE_000937"
     CDS             complement(24062..24286)
                     /locus_tag="ACF3UE_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634390.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24477..27254
                     /locus_tag="ACF3UE_000938"
     CDS             24477..27254
                     /locus_tag="ACF3UE_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3634391.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            27335..27754
                     /locus_tag="ACF3UE_000939"
     CDS             27335..27754
                     /locus_tag="ACF3UE_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3634392.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            27766..28236
                     /locus_tag="ACF3UE_000940"
     CDS             27766..28236
                     /locus_tag="ACF3UE_000940"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3634393.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28253..29032
                     /locus_tag="ACF3UE_000941"
     CDS             28253..29032
                     /locus_tag="ACF3UE_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3634394.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29019..29840
                     /locus_tag="ACF3UE_000942"
     CDS             29019..29840
                     /locus_tag="ACF3UE_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3634395.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            29857..30906
                     /locus_tag="ACF3UE_000943"
     CDS             29857..30906
                     /locus_tag="ACF3UE_000943"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3634396.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            30919..31923
                     /locus_tag="ACF3UE_000944"
     CDS             30919..31923
                     /locus_tag="ACF3UE_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3634397.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32556..33575
                     /locus_tag="ACF3UE_000945"
     CDS             32556..33575
                     /locus_tag="ACF3UE_000945"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFD3634398.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            33618..34499
                     /gene="galU"
                     /locus_tag="ACF3UE_000946"
     CDS             33618..34499
                     /gene="galU"
                     /locus_tag="ACF3UE_000946"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFD3634399.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            34799..35176
                     /locus_tag="ACF3UE_000947"
     CDS             34799..35176
                     /locus_tag="ACF3UE_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634400.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
BASE COUNT        11541 a         6207 c         7246 g        10242 t
ORIGIN      
        1 taataattat tcattaaact cttaaacaac ttcagaaaat attaattatt ctgaaaattc
       61 caataaaggg gtacgtaaaa tgaaaaagaa atttacattt ggtttggttg cggtatgcgg
      121 ccttgtactt gctggatgtt atggcggcag ttcagccaca agcagtagtt cagcaaaaag
      181 cggttcagca gatggaggag gcgtatttaa cttagtcgtg cctcaagaaa tgcctacagc
      241 tgacttatca gttgcaacag atacaatcag ttttacagca ttgaataacg tttatgaagg
      301 aatttaccgt cttgatgaag acagcaaacc acagccggca ggagctagcg agttggcaga
      361 agtcagtgaa gacggattaa cttacaaaat caaattacga gaagacgcaa aatggtcaaa
      421 tggtgatcct gttacagcag cggattacgt ttatggctgg caacgaacag tagacccagc
      481 tacagcttct gaatatgctt acctgtatgc gccagttgaa aatgcagaag acattacagc
      541 tggaaagaaa gataaatcag aactagggat caaagcagtt ggtgactatg aattagaaat
      601 caaattgacg aaacaaacac catatttcca atatctgctt gctttcccat catttttccc
      661 acaaaaacaa tccgtagtgg aagaaaatgg ggatgcctat gcatctgcaa gtgataaagc
      721 tgtttataat ggaccattca cattagaaga ttttgatgga ccaggaacag atacagaatg
      781 gacttataag aaaaatgatc attactggga caaagataca gtaaaacttt ctgaaatcaa
      841 agtcagtgta gtaaaagaat cttctactgc attgaactta ttcaaagatg gccaagcaga
      901 tgacgtgatc ttgtctggtg agttagcaca gcaaaacgca aacgatccag cttatacttc
      961 tgttaaagaa gcgcggacaa gctatatcga attcaatcaa cgtgaaaaga attcaccatt
     1021 caacaatgtg aacctaagaa aagctatttc ttattctatc gatcgtgaag ctttagtaaa
     1081 acaagtacta ggtgacggat cagttgtctc tacaggattg atcccatcag atatggtaaa
     1141 aagtccaaca acgaacgaag actttgcaaa agaagctgga aaattagttt cttatgacaa
     1201 agataaagca aaagaatatt gggaaaaagc gaaaaaagaa ttgggcgttg attctttaga
     1261 atttgatttg atggcttctg atgatgattc atcgaaaaaa gtaatcgaat atgttcaaaa
     1321 ctcaatccaa gaaaacttgg atggcgtaac agtcaaacca acacctgttc cattctctgt
     1381 acgtcttgac cgctcaactt cgggtgattt tgacgcagta ctaggcggat gggctgctga
     1441 ctatgcagac ccaagcagct ttactgattt gtttgtcaca ggtaattcat acaaccgtgg
     1501 tcgctggagc aatgcagaat atgacgaagc agttaaagca gcttcatcaa cagacgctgg
     1561 cgatgaacaa gcccgttggg atgatttcca aaaagcaatc aagatcatct ctgatgatat
     1621 gggtgtcgtt ccggtgtacc aaaaagcaga aggtcaccta gtgaatgaaa aaatcaaagg
     1681 tatcgttcac catgcggcag gcgcttcatg ggattacaaa tggacatacg ttgaagaata
     1741 atcgttaata ccgtgagcat gagaaaaaac gaggctgcgg caaatgtcgc aacctcgttc
     1801 tcatattcac ttatcctaac aaagaaaaaa gcatgaaaat agcagaaaga gcaattagta
     1861 ttccggcaat gatcagccaa aagctgtaca taccgtagct ggcagacgag agcgaggaaa
     1921 attctggttt tttctttcgg ttccttgttc gtgcaagatg gaccgatcgc tgaaaatgat
     1981 cgaagaaacc cgaagaaaag acccataaaa aaccgccgat aatcagaaac ggcaatgacc
     2041 ataagaatag atcattagat aattgaatga gtgtaaagga atggttgatg agatttttta
     2101 ttaaaataac cagaatcagt agaaaagcta ctgcgtaggg gatagatttt tttttcattt
     2161 gattgctcct ttatttttgg ttcattatct aataatgtag cgaaacatct gtcagaagtc
     2221 aaaagctagg gggaaacatt agtgaatagt tatatcaaat atgtattaaa acgtgtcttt
     2281 ttcatgatca tcacgctttg gttaattgca acaatcacct ttttcttgat gcaattgctg
     2341 ccgggcacgc catatacgaa tcaggaacgt ttgagtcctg aaacaatcga gatgctaaat
     2401 aaacaagtcg gtttggataa accagttatc gtacaatatg ggatttatct ttctaatttg
     2461 cttcaaggag attttggaat ttccttccaa tttaaaaacc agccagtcgc acatttgtta
     2521 gctggaagaa tcggaccatc cttgcagtta gggttacagg caattatctt tggaacagtc
     2581 ctagggacga ttttaggaac gatctctgcc atgaagcaaa atacatgggc agatacatct
     2641 tctacactcg tagcgatatt aggtcgttcc attccaaact ttgtatttgc tgttttatta
     2701 caatatatct ttgcaatcaa attacaagtt ttgccaatcg caaaatggga tggctttgtg
     2761 tacacaatct taccaacaat tgcgttggcc atgtcgccgc ttgctgactc tgctcggttt
     2821 atccgtacgg aaatggtgga agtactgcat agtgattatg tggaattagc aaaagcaaaa
     2881 ggattgagcc gttgggaaat cgcctttaaa catggtcttc gaaatagttt gattccattg
     2941 atgactttat taggaccgtt agctgtagca ttgatgaccg gatcactggt ggtagaaaat
     3001 atctttgcta ttcctggtat cggggaacaa ttcgttaagt caatcacaac aaatgattat
     3061 cctacgatca tggctgtaac gatcctttac tcatttatgc tgatttttgt tattttgatc
     3121 gtggatctat tgtacggtct agttgatcca agaattcgtg tttcagaagg gagccgagga
     3181 taaatggaaa tgataccaaa gcgttatgaa acagttgcag atatccctgc ggatgaattt
     3241 cttccattac aaaaaaatac cgaagaagaa cgtgaacaga ttactgcacc ttctttgaat
     3301 tttatccaag attcatggcg ccgtttaaag aaaaacaaag ctgccgttat ttcaatggtt
     3361 ttactattgg tcatcatttt gatctctgtg atcacaatct ttgtttctcc tcatgatcca
     3421 actgcccaaa acgtggctta tatcaatttg cctcctcgta ttccgggaat caatatcgat
     3481 ggattgaatg gaaaagcaat ggttggtggt gaacttgttg ataaatatgc tcaagcaaac
     3541 gtcccttcaa acgtaaattt ctttttagga acagacggtt tgggacgtga tgtattaagc
     3601 cgcttattta tgggaatgag aatctcgttg ctgatcgcat ttattgctgc attactagat
     3661 gtaacgattg gtgtagctta cgggttggtt tctggtttgt taggcggacg tgtcgataac
     3721 gtgatgcaac gttttttgga aatcttatca ggaattccaa acctcgttgt catgattttg
     3781 atgttggtcg tttttgaacc aggaattttt tcaatcgtgg ctgctatggc catcacaaac
     3841 tggataccaa tggcacgtat cgttcgtgca caaacaatga aattaaaaga tcaagaatat
     3901 gttttagctg gattgacatt aggtgaatca agaatgaaaa ttgcattcaa acatattttg
     3961 ccgaatatct ctagtgtcat tattattcaa atgatgttta gtattccatc tgctattttc
     4021 ttcgaagcct ttttaagctt tatcggttta ggtcttacgc ctccgtcagc ttcattagga
     4081 acgatgttga gcgaagggta caagacattc ctgtatctgc cttatctatt atggattccg
     4141 gcagtaactt tatcggttat catgattggc tttaacttac ttgctgatgg attgcgtgat
     4201 gcctttgatc ctaaaatgaa agagtgaaga cgatgacgaa aattttagaa gtgaaagact
     4261 tagaaatctc ttttgatacg tatgctggaa aggtacgagc gattcgcggt gtcaattttc
     4321 atttgaataa aggagaaaca ttggcgatcg ttggggaatc tggaagtgga aaatcagtga
     4381 cgaccagaag catcatgcgc ttgctgtcaa gcaacgccaa tatagatgct ggtcaaatcc
     4441 tctttaaagg taacgatatc gttggaaaat cagaaagaga gatgcaaaaa atccgtggta
     4501 aagaaatagc gatgattttc caagatccaa tgacctcttt agatccgacg atgcccattg
     4561 ggaagcaagt cgctgagtcc cttagaaagc ataataaagt ttcaaaaaaa gagggacaaa
     4621 aagctgcatt agaattgctt aaattagttg gaatacccga agctgagaaa cgtatcaaca
     4681 gttatccgca tcagttctca ggaggtcagc gtcaacggat cgtgatcgcg attgcactgg
     4741 tatgttatcc ggaaatcctg attgctgatg aacctacaac agcgcttgat gtgactattc
     4801 aagcacagat tttggagctg ctgaaagaaa ttcagacaaa aatcgataca tcaattatct
     4861 ttatcactca tgaccttggt gtagtagcga atgtcgctga tcgtgtcgct gtcatgtatg
     4921 gaggaagaat cgttgaagtt ggaacatcgg aagaaatttt ctacaacccg caacatccct
     4981 atacttgggg actgcttggt tcaatgccga cattagatag tgcgaacgat cgattgtatg
     5041 ctattcctgg ttctccaccg gatttattga acccgccaaa aggagacgca ttctatccaa
     5101 gaaatgaatt cgcgatgaaa atcgatgcag aacaagaacc accatttttt gaactatcaa
     5161 aaacacacaa ggcagcaact tggctacttg ctccgcaggc acccaaagtg acaccgccag
     5221 aagaaatcca acgtcgctgg gctatcttta aagagaaaca aaaacatact tacggtcaag
     5281 gaggaattgc tgatgccaaa taaactactt gaagttaaag gattgaaaca gtatttcaat
     5341 gtaggaaaaa agaatgaagt acatgctgta aatgacatca gctttcacat ttatgaagga
     5401 gaaacattcg gtttagttgg agaatctgga agcggaaaat ccactactgg ccgtacgatc
     5461 attcgcttga atgaacctac tgatggtgag atattattcg acggtcaaga tataacgaag
     5521 atcaaagata aaaaaggttt gacgaaattc cggcatgatg ttcagatgat ctttcaagat
     5581 ccatacgctt cgttgaatcc tcgtatgaaa gtcagagata tcattgccga aggaattgat
     5641 gttaatggac tagctaaatc atctgaagag cgtgcaaaaa aagtcgatga tctattgaga
     5701 actgttggat tgaatccaag ccacggtact cgttatcctc atgaattttc aggtgggcaa
     5761 cgccagcgta ttggtattgc acgagcattg gcagtaaaac cgcgttttat catttgtgat
     5821 gaaccaattt ctgcactaga tgtgtcgatc caagcccaag tggtcaattt gttgcaagat
     5881 ctccaaaaag aacatcaatt gacctatcta tttattgcac atgatttgtc gatggttaaa
     5941 catattagtg accgaatcgg tgtaatgcat aacggcttgt tattagagat gggaacaagt
     6001 gatgaaatct ataatcacgg tgttcatcct tatacagaaa gtttgttatc tgctattcct
     6061 ctaccagatc cagaccatga gagaaaacgc agaagaatca aatatcaacc tgaaccagat
     6121 gacggacaag tacgtcaact tcgtgaaatc gcaccagaac attttgtcta tgcaactgag
     6181 caggaagtcc catattacgc aaaaaaacta aaacgacaaa aggaatctct tctggttgct
     6241 aactaggagg gacatagatg ctaaaagctt ttaaattccg tatgtatccg acagaagaac
     6301 aaaaacagca attgattcgt acttttggat gtgctcgatt tacctataac catttgctga
     6361 aaaagcggca gaaaagttgg caacaaacag gagtagccaa tttttcgctc acacccgcta
     6421 cattaaaaaa agaataccca ttcttaaaag aagtagacag tcttgcttta gcaaatgcac
     6481 agcttaattt ggatcgggct tttcgcaatt atttcaaggg acgtgccagc ttcccaaagc
     6541 ttaaaacgaa aaaaagtatg tggcaatctt atacgaccaa caaccaaacc cgtacgatct
     6601 atctggaaaa tggctactta aagttaccaa aacaaaaaga actaatcaag ataaatcagc
     6661 atcggccagt tgaaggatcg attcgctccg ctacgatttc tgctcgatat aatgaagaat
     6721 tttatgtcgc actactttgt gatgtttcgc cagtaaaaaa agaatcttta gctaaatgga
     6781 tcgggatcgc ctatcatccg aagacattga tccaaacatc tcgacctcta gaagtaactt
     6841 taccaaaatt tcaccagaca gaagaaaagc tgcaacatgc acagcggaaa ttgaatgtga
     6901 aagtccgctc cgctcaccat agaaagatca ggttagatca ggcaagcaat tatcagaaac
     6961 aaaagagaaa agtaatggat ctttatctga aacaaaagaa ccagcgagaa gattatcttg
     7021 aacaattatc tgggaaattg gtcaaacaat atgactactt atttgtagaa tcttttccaa
     7081 aagaagaggc acatgctgat ttttctattc acgactggca taaattaata acaaaattgc
     7141 gttataagtc ccaatggtat aataaaaaat ttcttttgat caataccgac ggagcagaag
     7201 aaagcaattc cgtaagaaag agccaagtag tagaaaaaat gggcagacat tcggttatca
     7261 agggataaaa aatgaatgaa actgatagga gcgttagggt tagccttgtt aataaaaagt
     7321 cttaatgact tttgtttcta ggaatttttc ttttgaagaa aagctcacta attatgacaa
     7381 accaataaaa caatagcaga aaaagttcgt acgagctttt tctgctattg ttaatttttt
     7441 attcagaaag tttacgaata catcaaaatt ctgaaacaaa aaacgtaact cacaaagagt
     7501 tgtttttgcg ttttttcttg aatgattagg tctgaatctt ttgctcacaa ccttattcat
     7561 ggtgccccgg cttgagctga tagatttttg aaggacggcc gattcctaca ggacgttcac
     7621 cgatctcatc gaaatattgg agcatagctt tcttaaaatt ggaatgatcg atcgttttat
     7681 aatcgatccc taagaattta gcaaatactt ttcgagcttc cgtaatcgtg aaatctttac
     7741 ctaaaacttg tagaacttgc ggctcgtgtt ccattttatt gactacacgg ttgaatgctt
     7801 tcaagatgat ttgactatgg tcaaaagcca aagtatcttt gccagaagac tctccagtga
     7861 ctaaatcaag cgagatagcc acttctccgc tagataaatg gatcttgtta ctatgacgtt
     7921 ctagtgtgaa ccagcgtact tccttggcat catctccggc gattagcggt tcttctccaa
     7981 taaaggctaa gtagctgact gtgacgaccc agcctcgcgg atctcgatta ggcgtactga
     8041 atgtatgcag ttgctcaata ttttcttttg aaataaccac accagtttct tcctttgttt
     8101 ctcttaagac gctttctcca gttgactcat ccttttggac aaagccacca ggcaatgccc
     8161 atgaatttcg ataaggatgc ccttttcttt ggatcaacaa aactttcagc tgatcttctt
     8221 ctttgttata gcacatcagt acgatatcga cagtcaaaga gggcttgtca tattctggac
     8281 gttcctgttt ttgataccag ttaagaaatt cttcttcact tgctttatgt tcataatata
     8341 atttttcttc ttctttagaa gcaaaacggt tcatctgacc acctccattg acagtaaaag
     8401 tactttttac cttattgtag cagactctga aaaaaaacca aggatttact tgaaaaatct
     8461 aggttatcat ttaaatatga aaaataaatg gaagtatgag attgaataaa aagaaaagca
     8521 gataaaacgg caatacttta taccgctctt cacgaatggc aaagaagcca caaataacga
     8581 tatatacgtc aatgataaaa cgcaaaatcc aagctgctgt cataaaactg ttcaaatgcc
     8641 catggaggtt aaaataacca tacatacgaa tataaaaata gctgaatatt aaatgtgcta
     8701 atgaaagaaa agcaatacta agtgtaaaaa aaagatgttt cttctgcatg attgttccag
     8761 tcccttacta agatagatag tctttattat accacgtgtg aggggagaaa taaaaagccg
     8821 ttttttagta gatatgaaac aaaacaaaaa cccgcattta ttcaacctat tcatcctttt
     8881 aaaggataga ttgaacgtag atagaagtcg tttatccagt ctttttcatt ttgaaaaaaa
     8941 gctaacagca tgcttttttt atggtatact agcaaggaaa cgaattcgca tcatgcgata
     9001 aaggaggaag agccccgtgg cagaaaagga aactttttat atcactacgc caatctatta
     9061 tccaagcggc aaacttcata tcggcaactc gtatactacg attgcatgtg acgcaattgc
     9121 tcgttataaa cggttgatgg gctttgatgt gttttatctc actggagtgg atgaacatgg
     9181 tcaaaaaatc gaaacaaaag cagaagaact aggtgtaaaa ccgcaagaat atgtagataa
     9241 aatggcggct gatgtcaaga aattatggaa aacgcttgat atcagttatg ataaattcat
     9301 tcgcacgaca gatgattacc ataaagcagc tgttcaaaaa atatttgatc gtttattaga
     9361 acagggagat atttacttag gtgaatatga aggctggtac tctgtttctg acgaagaatt
     9421 ctttacagaa acacaacttg cagaagtgta caaagatgac gaaggtaacg tgatcggtgg
     9481 taaagcgcca agtggacacg aagtagaatt ggtaaaagaa gaatcatact tcttccgcat
     9541 gagcaaatac gcagaccgtc tattggaata ctatgaagaa catcccgaat tcatccagcc
     9601 agaatctcgt aaaaacgaaa tgatcaacaa ctttatcaaa ccaggattag aggatcttgc
     9661 agtttcacga acaactttta cttggggagt accagtcaag agtgatccga aacatgtggt
     9721 gtatgtatgg atcgatgcat tatccaatta tattactgca ctaggatatg gctccgaaga
     9781 tgaaagtcta ttcgaaaaat actggcctgc agatgttcag atggtcggta aagaaatcgt
     9841 tcgctttcat acgatctatt ggccaatcat gctgatggcc cttgatttgc ctctacctaa
     9901 aaaagtattt gggcatggct ggctattgat gaaagacgga aaaatgtcta aatcaaaagg
     9961 aaatgtcgtt tatcctgaaa tgcttgtgga acgttatggt ttagatgcac tccgttatta
    10021 tttgcttcgt gctgttccgt ttgggtcaga tggtgtcttt acgccagaag attttgtttc
    10081 ccgtgtcaat tatgatctgg caaatgatct agggaactta ttgaatcgaa cgattgctat
    10141 gatcaacaaa tattgtgatg gactcgttcc tgactatgcc tcacttgtca ctccatttga
    10201 tagtgaactg tctacgacgg ctgctaacgt tgtcggacgt taccatgatg caatggaaaa
    10261 aatggaattc aatacagcat tggctgaaat ctgggtgctg atttctcgtg caaacaaata
    10321 cattgatgaa acagaaccat gggtattagc aaaagacgaa gaaaagaaag ctgaattgaa
    10381 tagtgtcatg atccatttag ctgaatcttt gcgtatcgca gcgatattac ttcagccaat
    10441 catgacagaa acgccagaga agatcttcaa tcaactagga ttggactctg aaacaatgaa
    10501 tcttgaagga ttacactttg gcgaatttcc ttcaggaaca aaagtagttg caaaaggtac
    10561 accaatcttc ccacgtttag atatggaaga agaagttgct tttattcaag aaaaaatgtc
    10621 tgaaggtact caaacaaacg aagatacagt caaatgggat ccagaagaaa cagaacttgt
    10681 ttcaacgaaa gaaaaacaaa tcaaatttga tgtatttgaa aaagtagaac taaaagtagc
    10741 agaagtcatc aactgtcaaa aagtagaagg ggcagataag ttgctgcaat tccgactaga
    10801 tgctggagac agccaagacc gtcaaatctt gtcaggaatc gctgaatttt atcctgatcc
    10861 aagcgaattg atcgggaaaa aagtcgtcat tgtagcaaat ctgaaaccac gaaagatgcg
    10921 tggacaaatc agtcaaggaa tgatcctttc tgcagaagca ccagatggct ctttacaagt
    10981 aatcgaagca ccaaaatcca tgccaaatgg ctcagaaatc gcatagaaat tcaaaggggg
    11041 tatgacacta gttgtgtcat accccctttt tccgaaattt gagaagcaat tttcgtaaat
    11101 tccttcttat tacttgaagc caatcatata atacagaaac agagaactat ccaaaataaa
    11161 tcctagaaaa agaagtacga gcttcgctga tttttgttaa tttagaataa tactaatagg
    11221 aatcgtaaaa acagaaaaaa agcataatga taaagggtcg ggcagatttt aattgattca
    11281 tctggtactc ttttttattg tccttacatt cataaagttt gaatgcaatg actttattac
    11341 atctatattt atatctaaca gtagcgttga tgtgttaatt ataagttcta tcactttatg
    11401 ttcaattagt ttgtgctctt atatgtgtga ttgaaaatat agataaaaaa acaatcatcg
    11461 gctttgactt cgatgattgt tttctttatt ttgtaaaaat cctatcactt gattttatgg
    11521 taacctttta tttttgtctt caaacggctt ggtaagagag cagtaagcag tgcaaatggg
    11581 atcgaaaaga cataccagaa aatcgtacgt ccgataccat aatgttgata gagctttgtc
    11641 aacatcacgt gtaacaagat caaccctaaa agcaaggagc cagctataaa ccaatgatta
    11701 tcccaatgca tgacttcact aagtgccatc actccaaaag gatagaaata aaaatagatc
    11761 ccgactaagg tcatccgcca gttctttgta aatgttccga tattcaataa aaagaaaatc
    11821 gctgaaagca aaataccgat aggcggaaaa agcccaacca aaaaggaata caacatcccc
    11881 cacaagatca tcacaggacc tttgatcaat gcaacgattg cgatgaacaa agtcagcaat
    11941 attagttttt gtgataacgt tgcaacagtc attaatccaa ataaaattaa tgtgaaccaa
    12001 tgccaatggg actgctgttg ttctttacgg gaaaaatcga cccggttgga taaataatct
    12061 gctaatttcg gataagaacg cttaaaatcc ataaactgtt cctccttcgt ggaaaaggta
    12121 ggtttagtat acgaaaaata aaaaagaaat acatccgtct taagagggag tttttcactg
    12181 aaagtggaga aaaaagaatg gtaaattaaa atattctcag ttatactgaa aattatacca
    12241 aatttcaaag aagaaagagg atgggaatga aaggcaaact aaaacgagaa atcaatctgt
    12301 ttggcgcatt agctaccgtt atgggaaccg tgatcggtgc aggcgtcttc ttcaaaactg
    12361 ctgctgttac tgctagtact cagtctacaa gtttgacatt gctagcttgg cttttgggtg
    12421 gtttcttaac gatctgtgct ggattgacag tggctgaatt agctacagca atcccggaaa
    12481 ctggtggagc tgtaaaatat attgaagctg cgtatggaaa attgcccagc tttttattag
    12541 gatgggcgca aagcttgatt tactttcctg ctaatattgc tgcattatcg attatctttg
    12601 cgacacaatt gacgaactta ttacaattat ctaccgatta tcttttgttg attgcagtga
    12661 tcaccgctgt ttctgtgaca gggttgaatt tgttagggac aaaagtcggt gcttctgtac
    12721 aatcagtgac gttgattgtt aaattaatac caattgctgt gattgtcata tggggattat
    12781 tgaccccagg acaaggaact gtccagttat ttccaatcga agctggaaaa gatgttactt
    12841 ttgtcgaagg attgagcagt gcgttgttag caacgttgtt tgcttatgac ggctggttag
    12901 gtgtcggtgc aatggcaggg gaaatgaaac ggccggaaaa agatttgcct aaagcaatta
    12961 ttcttggttt gagttttgta acagtcgttt atctattgat caattttgtt tttttgaaaa
    13021 ctttgccgat tgatcatctt gccggtaatt tgaatgcagc ttctgaagca tcagacgtca
    13081 tttttggagg aatcggtgga aagctggtca ctattgggat cttgatctcg gtatacggtg
    13141 cattgaacgg ttatacacta actgggatcc gcgtgcctta tgcgatggct ttagaagacg
    13201 agctaccttt cagtaaacag ctgacaaagc tttcaaagaa gtttacggtt ccttatgttc
    13261 ctgcggtttt ccagttagca gtagcttgta ttatgatgag ccttggttct ttcgactttt
    13321 taacagacat gttgattttt gtgatgtggc tattcagttt actgattttt atcggtgtct
    13381 ttattttaag aaaaaaagcg ccggaattgc cacgtccata taaagtacca ctttatccaa
    13441 tcgttccgat tattgcgatt ctcggtgcta ttttcatttt aggtatgacg atgatgacgc
    13501 aaacgaaatt agcattgatc ggtataggtg ttaccttgat aggtatccca gtctattatc
    13561 aaaaaaagaa aaaacgctca gaagagtaaa atatttcaac aacagacaga aaaagtacga
    13621 actaggtcct ctagatcttc gtgctttttc tatttcaata aaacaagttc ttctattttg
    13681 atttttgcta cttctgcaag tagtgcttat gtgctaaagt aagaatgaaa aggagagata
    13741 aacatgatat ttgattctca tacccattta aatgctgaac agttcaatga agatattcca
    13801 gaaacgattc agcgagcaca agaaatgggg gtaacgaaaa tggcggtcgt gggcttcgat
    13861 acgccaacga ttgaaaagtc tttgcaatta agccatgact atccaaatat atacagtatt
    13921 atcggctggc atccgacaga ggctggcagt tatacgaaag aaatcgaaaa taaattacaa
    13981 gaacaattga ctttaccaaa ggttgtagca ttaggggaaa ttggcttgga ttatcattgg
    14041 atggaagacc cgaaagaagt ccaagataaa gtatttcgca gacagattgc tatcgcaaaa
    14101 gaaatgaacc taccaatcag tattcatact agagaagcac ttgaagacac gtatcaaatc
    14161 ctaaaagaag aagatgttcg agatatcggt ggaatcatgc atagtttcag tggtgattat
    14221 gaatgggcaa aacgatttct tgacttaggg atgcatattt catttagcgg tgtcgtcact
    14281 ttcaaaaaag cattagacgt ccaagaggct gcagcaaatg taccaatcga acgattactt
    14341 gtggaaacag atgcccctta tctggcacca gttcctttta gaggaaagcg aaatgaacca
    14401 ggctatactc gttatacagt agaaaagatt gctgaacttc ggaatcttcc gacagaagaa
    14461 gtggctgccc aaacatggac aaatgcgcac cgattatttg gtctaagcga acatggataa
    14521 gatgaagatc caagagatta tagtcgttga aggaaaagac gatacaagaa ggctgcggga
    14581 agtagttgat gcagatacga tagaaacaat agggtctgca atcaatgaag agatcctgat
    14641 gcaaattgaa catgcccaag agactcgtgg agtgatcgtt tttaccgatc ctgatttttc
    14701 aggagaaaaa ataagaaaaa tcattatgga agctgttcct caggcaaaac atgctttttt
    14761 gccgcgcaca caagctaaac caaagaaaaa gggaagcctt ggtgtcgagc atgcaagtga
    14821 tgctgctatt ttagaagcat tgaaaaaggt cgtgacgcca gacatttccc aaacggctgt
    14881 ttctgaaatc actagacaag accttttaga ctatggttta atagctgggg cacaagcaaa
    14941 agaaaaacga gaaaaactag gtgacgagtt gcgcatcggt tacacgaacg gcaaacaatt
    15001 ggaaaaacgt ttgaagatgt ttcgtattac gccgaaagaa ctcgcccaag caatgaaaat
    15061 agtggaggaa caacatgagt gaatatcgtg aaattgcgac accctctaga acaaaagaga
    15121 ttttattgaa acatggtttt tcatttaaaa aaagtttagg acaaaatttt ctgactgaac
    15181 caaatatttt aaggaaaatc gtagaaactg cgcaaataga tgaacatacg aacgtgatcg
    15241 aagttggacc aggaatcggt gcattgacgg aacaattagc caagcatgca aaacaagtcg
    15301 tagcatttga gatcgatgat cgtttgatcc ctgtattggc tgatacgatg caaccctatg
    15361 acaatgtgac tattgtacat caagatattt taaagaccga tttgtcaaca gctgttagag
    15421 aaacatttca tgaggagctt ccgttaaaag tcgtagcgaa tttaccttac tatattacga
    15481 caccgatcat gatgcatttt cttgaatcag atttggttgt ggatgaacta gtcgtcatga
    15541 tgcaaaaaga agtagctgat cgtatctctg ctgaaccagg aacgaaagct tatggttcat
    15601 tatcgattgc tgttcaatat tatatggaag ccagtttagc attcatcgta ccaaaaacag
    15661 tatttgtccc tcagccaaat gtagattcag cgattttgaa actgacaaga agagatatac
    15721 cggcagtcga agtgacagac gaaaaagcat ttttccgatt gacaaaagcg gcatttcagc
    15781 aaagaagaaa aacgctttgg aataacttgc agcattcgta tggcaaagat gaccagacaa
    15841 aagcatggtt agcaaaaagc ttggaaacag ctggaatcga tccaaaacgt cgtggggaga
    15901 ctttgtcatt acaagaattc gccgcattaa gcaatgcgat gtcagaaaat atgcagtaaa
    15961 aaaagaggtt gtgacagaag ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc
    16021 aaacaaaaat agttcctcat gtttttcgtt tgtttgggct tattaccgca gatgcaagct
    16081 tttgaacacc gtttaagaaa gaggttgtgg gcctgccgtt taactctaag tcacaaggaa
    16141 caatttcaaa aaacagcttc tcatgttttt gagttagttg gtcttattac ttgatgcaag
    16201 cttttgacca ctattatgcc gaacaaggag atgtgacaca aattttgtca catctcctat
    16261 ttttgtttct tgatcaaaaa attcttatac ttgatactca cactcatttt gtatggattt
    16321 agaaaagaat atgtgtcttg acagttatta gtaagtgagt tatactaagt cgacatttat
    16381 gtgtcaagac atattaggag agagaaaaaa tgagaaaaaa ttcagttcga aaactaacga
    16441 tttctgcttt attgattggg atgggggtca ttatcccaat ggtcatgcct aaaatcatga
    16501 ttccaccagc ttcctttact ttggcgtctc atgtgccatt atttattgcg atgtttttta
    16561 caccaggagt tgcagtggct gttgcgctag gtacgacatt tggtttcttt ttaacaacgc
    16621 cggttatcat cgcattgcga gcattgtcac atcttgtgtt tgcgttgatt ggggcttggt
    16681 acttgcaaaa gcatccgagt atcgttttaa aaaatggaca gtttactttt gctaattggc
    16741 gtttccaagg gttcaatttt gtgatcggtg tgattcattc tttagcagaa atgctagtag
    16801 tcagcatctt ttactttatt ggtaatatgc ctgaaacata ttattctcaa ggatattttt
    16861 atacagtatt catcttgatg gggattggtg ggcttatcca cagtttagtt gattataata
    16921 ttgcttattt tatagcagga acactcagca aatattttga tatccccgta tttacggcag
    16981 caaaaaaaga aaatcggaaa gagtcgattc aagggtacgc gaagaaaacg acatattaga
    17041 catgatctct caaaaaaaaa actctcatct agtaatggat aataaatcct ctaagatgag
    17101 agttttttgt cctaaaaaga gctgcaccaa catcttctgg cacagctcta acagggggca
    17161 atttatggaa gtttgatgac ttgttctgtt tctttatcaa agaagtggcc tttgctgatg
    17221 ttgaaggcaa ggtcgactat ttcgcctggt ttatggaaat ctcttgcatc tacttttgag
    17281 atgaactcag tagaaccagt ttttgtgtaa agcatcgttt cagctccaag taattcggaa
    17341 acgacaactt ctgatttcac tacggcttca ggtgaagctt caagggctac ttgttcactg
    17401 tggatgtctt ctggacgaat accgaagata acttcttttc cttcataacc tttttcaact
    17461 aatactttgt tttttccttc aggaatacga agcttaagcc catgtccatc tgtgataaca
    17521 ccatttttca atgtcacatt aaagaagttc atggcaggag atccaataaa gccggcaacg
    17581 aacatattga cgggtgtatc ataaacttct ttcggtgtac cgatttgttg gataaatccg
    17641 tctttcatga taacgattcg gtcagccata gtcattgctt ctgtctgatc gtgagtaaca
    17701 tagatggtcg ttgtttcaag acgctggtga agtttggcaa tctcagcacg catggctaca
    17761 cgtaatttag catctaaatt tgataatggc tcatccatta agaagacttt tgcatcccga
    17821 acgattgccc gtcccaatgc cacacgttgg cgttgtccac cagataaagc agctggtttt
    17881 cgtttcaagt attctgtcag acctaagatc tctgctgcat tgtccacacg ttttttgatg
    17941 tctgctttat catatttacg taatttcaag ccaaaagcca tattatcaaa aacagtcata
    18001 tgaggataca atgcgtagtt ttggaaaacc atggcaatat cacggtcttt aggtgccacg
    18061 tcattcatga cttttccgcc gatatttagt tctccttcag agatatcttc cagtcccgcg
    18121 atcattcgca aagtagttga ctttccacaa ccggaaggac caacaaaaac gataaattca
    18181 cggtctttga ttgatagatt aaaatcagtt acagaataat tttctgcatt gtcatatttt
    18241 ttatatacgt ttttcagagc catttctacc ataatacgtt ccacactttc ttttttagtt
    18301 ttattaacta tttaaagtat aaatgaaagc gttaactaac ttcaatgtca tgttgaacaa
    18361 gaattttttc ttttttttgt caatgtgcta gttttaagct ttaataaata tccataagaa
    18421 ataaaaactg atacactgga gtaaataagt atgttaacaa tatcaaaagg agtgtctctt
    18481 atgaaaatcg ctttgatcgc tcatgaccga aaaaaaccta tgatggtgaa attagcaaca
    18541 gcgtataaaa caatattgga aaaacatgaa ctttttgcta ccgggacgac tgggcagagg
    18601 atcacggaag caaccggctt gccgatccat cggtttaaat ccggaccgtt aggcggggat
    18661 cagcaaattg gagccatgat ttcggaggat cagttagatt tggtgatttt tcttcgagac
    18721 ccgctggctg cacagcccca tgaaccagat gtaacagcac ttatccgttt atctgatgtc
    18781 tatgagattc cgttagctac gaatatcgga acagctgagg tgctactaag aggactggaa
    18841 gccggcttcc tagattttcg aagaatcgtc catgaaatag acaagcatcc actttcattt
    18901 tgatggataa gcgtatggaa aaataacgtt taatgttcgc ctatatgtag ctataaaagc
    18961 taaacaaact gataatatgc gatataatac gaacgtattg gataatataa acaataatat
    19021 tagtttttcg tatttgcagt aaatgtgaaa atatgctata gtttctgtgg gaaaagatcc
    19081 caaaaataat acagagtaga aaataaagcg ttaagtgcta agaggatggg atgttgcctc
    19141 ttggacgaag gacgtaatgt tcgcggtttt attttcgcat tcgctgcatg atacgatgta
    19201 gcagctctta aaggagatgc taaaaatgaa gaaacaccgg ttagacgcac gtatgattgc
    19261 tattatgggc ttattgattg cattgatggt cactttgtcc cgactggtag caatcgagac
    19321 cccatttatt aaaatcagtg tcacatttat tccacaagtg atcatgggca ttctttttgg
    19381 tcctttttgg tcagggatag gcgcagtttt agctgattta gtaggaatgg ccctcttctc
    19441 gaaatctgca ttctttattg gatttacatt gaatgcattt attgaaggag caatctacgg
    19501 attctttttc tatcgaaaag agatcacttg gaaaaatgcc attctggcta cgcttagtgt
    19561 cacgctgatc atcaacttat ttttgacacc attatggctt gcgttgatgt accatgtgcc
    19621 attgttcagc tgggtcgttt gggcgccccg cctgttaaaa acagtaatat ggttaccgat
    19681 tcaatcaatt gccatttatt acgtaggacg tagtattcct tacaaaaaaa ttttaagaag
    19741 tttagcgatc cacgctaaat aaaaaacaag cagtcttccc atcccagaag actgcttgtt
    19801 tttattgtgc tgtgaattgt gcttgataga gccgtcggta ataaccatct ttttgaagca
    19861 gctcatcatg ggtgcccatt tcgacaatag ctccctgatc catcactaat atctggtccg
    19921 catttttgat tgtggacagg cgatgggcaa tcacaaaact ggtttttcct tccatcattg
    19981 ctaagaaggc ttgttggatt tttttctctg tcaatgtatc gactgagctg gtagcttcat
    20041 ctaagatcaa cataggggga ttactgatca tcgttcgagc aatcgtcaac agttggcgtt
    20101 gtccatctga tatctttaac ccttgaccgc caatcttagt atctaatttt tccggcaaac
    20161 gttctacaaa ttcatacata taagaggctt ttagggcatc attgatttct gcgtcacttg
    20221 cttccggatt cccaaaacga agattttctc gcaatgtact gtcaaatagc caagtatctt
    20281 gtaacaccat tccaaaactt ttacgtaatg tatcacgttg gatagagcgg atgtcatggt
    20341 catcgactgt aattgttcct tttgttgtgt cataaaaacg catcagcaaa ttaacaagtg
    20401 tggattttcc ggcccctgtt tttcctacta tagcaatggt ttgacctgga taagcagtaa
    20461 aattgaaatc ttcgatcaaa cgctgcttgg ggtcataaga aaaagaaaca tgatcaaaag
    20521 agacttttcc tttgatattt ttgggttcca aggcataggc atctggcaaa tcaggctttt
    20581 cttctggctg atcgatcaaa tcaaatgctc gttctagacc agaaaaagcg gtttgcagtt
    20641 gtgtcgtgat tccagaaagt tcgataaatg gtttagaaaa ctgacttgag tagatcgtaa
    20701 agctggaaat cacaccaaca gtgattgacg aaccactctt caatgccaat aggccgccaa
    20761 ctaaaccaat cgataaataa gcaaggtgat ctacaaaacg agaagacggg tttgtcaagg
    20821 aagaagaaaa ttgtgcccgt tgtccttttt catatagatc agcatttagc agttcaaatt
    20881 gctgttgact agcttcttct tgctgaaaag ctttcacgat tttctggtta ccgattcgtt
    20941 cggtcacaaa gcccgagata tccccaataa tcctttgctg tctatcgaaa tttgtttgtg
    21001 aagcacgagc aacgatccaa ctcacaagga aaataattgg tgtagaacaa agaacgacca
    21061 atgtcagaag tggacttaga cgcatcataa aaataaacga aagaatgatg attgccactc
    21121 cagaaaataa ttgattgaag gccgcagaaa ttgcaatgga aatattgtcc atatcatttg
    21181 taaatcgact gacgatattt ccgtgggagt tttgatcata ataacgaagt ggcaatcgat
    21241 tcagatgagc aaatgcatct tttcttaatt ttgcaacgga taagtaagct aaccgattgc
    21301 ttaacacttg gatgagccat tgactgacta cgttgattaa aacgatacca ccgaatagaa
    21361 taagtaaatg gaacagtcga ttgaagcgga cctgtccttc tccaatcatt tgatcgatac
    21421 tttgaccaat ttgtaacgtc atcacaactg ttgcaatccc attgatgatt cctagtatca
    21481 cagctagcca aatgtctttt gcataggcag taaggtaagg aatgaatcgg cggagcgtct
    21541 gcaaggataa tttttttact ttcataacta ttcttcctcc tgtgatgcga cgatttcctg
    21601 atattctgct gattgagcaa gtaattcttc atgggtaccc tgagcagcaa tcttaccttg
    21661 atccatcact aagatatgat gtgcttcttg aatagagcgg acacgttggg agataataat
    21721 cactgtactg ccaagataag tctgtagcgc cttacgcaaa tccaagtctg tttgataatc
    21781 caacgcactt aaagagtcat ctaaaatcag taatgctggc ttggcaatca aagctcttgc
    21841 aatcgtcagt cgctgttttt gtccgccaga gaaatttttc ccattttcca tgacttttgt
    21901 atctaaacca tttggaagct gacggacaaa ttcttctgcc tgagcgattt tcagagcttc
    21961 ccaacattct ttttctgtgg cgtctttctt accccattga aggttttcac gaatagtccc
    22021 ggtaaatagt acagaagttt ggggaacaag agcaatttgc tgacggagat gatccagctg
    22081 ccaagaacga acatccattc cgtccattat aactgtaccg gaactgacat catagaaacg
    22141 cggaatcaat tgtgtcaaag tcgttttccc gcttccggtt ggaccaatga ttccaaggac
    22201 tgtatttcgc ttcagctgaa atgtaatatt ttggagagaa agaccagaat caggagtata
    22261 acggaagtca acatggtcaa aagcgataat tgcttcagaa gaaaaatcgg gagtagtact
    22321 gacctcagct tcaagaatcg aattttctgt gtctagcacc tctttcaccc gatttcctga
    22381 agcttcggca cgtgtgaaga tcacgacgag gtttgaaaca acgatcagtg ccaaaagcat
    22441 ttgattcata taattgatca aagcaagaac ttgtccttgt tgcaagctac caatatttac
    22501 tttgatcccg ccaactgtca gcaaacagat gatcccgaca ttcatgatca aggttgtagc
    22561 aggtgataat agggcagaga tattggaaac acgtaaataa ttgttcgcta gatcatttgt
    22621 gcttttatcg aacttctctg tttctttttt tgtctgcgca aatgcgcgga tgacacgaac
    22681 accgctaaga ttctgactaa cgtgttcatt gagctgatct agtttttctt gcactttttg
    22741 gtagagagga acggtttttt tgatgataaa aaataaaatg attgagaaaa taggcaataa
    22801 tgctaagaaa aacagaccta cttcccagtc gatcacaaaa gccatgacca ctgacccgat
    22861 acttaaaaac ggtgctctga tcaataaacg aatgaccatt gctaaagcta gctgaagctg
    22921 attgatgtcg tttgtcattc gggtgatcaa ggtatctgtt ccaaaatgat tcaactcgtt
    22981 gtgagagaaa gtattgattt ttttgattag ctgattacgt aactctgtac caaatccttg
    23041 tgaagctact gaagcatagt attggcaaat gatagcacaa atcagaccaa tcacagacat
    23101 agcgaccatc cataagccca tttcaatgat ttttcctcgg tcattcattt ttagtccatt
    23161 atcgatcaag gaagccatca ttaaaggcag gacaagttcg aagacagctt caagaaattt
    23221 gaagaacggg cccaaaatga tttgcttacg atagtctttt gcataacgta ataactgaat
    23281 catatgattc ctcctattat ttatttgtcc acaattgaaa aaacaagtac taccacattg
    23341 tagcttagga aatttagaat gaaaagagaa caagcctttt cataaatgaa agttttatta
    23401 tgaagaagct ttagaaattg aatagactat tttttttaaa aaaaagaaaa tgagaaaaca
    23461 tgccagtctc ttcattcata ggaacgtcta ttttacttaa tttttctata aatgaattct
    23521 gcataaaaaa tatatcaagt aaatgtttat agatgaaact ctatttactt cttttttaat
    23581 ttgttcttgc aatctttttt gctacgtaat ttttgtaaaa aagtgggttg agagaaatct
    23641 aattgatttt caaagaagga gtatgaaaat gagaaaaata tttattcgtt tattgtgggt
    23701 actatcttag aggaataaat aatagtggag aaaactatgg tttggcgcag attctatcag
    23761 gtttgatgga acgaagacaa cctcccgaca tcaagtcaaa agctacttga gattttgatc
    23821 tgaaaataaa aaaagaaaac aaggtaggaa catcaatgtt tctaccttgt tttcgtaatc
    23881 aatgggaaaa aactaagagt ggtgtacgta atcaataaaa aggatggtga caacagtacc
    23941 tctttactct ctgaaagcat cataactcgt ttttcctcat tatgccaata aattgttgtt
    24001 ataccacata taaggatttg taatagctaa aaacagacag gaaagttgaa atctgtgaat
    24061 cttattttgt atggaaggat ttatagaacg caaaaatcaa gataaagatg aataaaaatc
    24121 ctgtttcggc tatatattgc gtatctacgc caataaaacg agtttgttct gtcatagcca
    24181 tataaagcaa aggcaaaaat acaactacag cgagataaga tccgatgatt tctcgaaaag
    24241 ttttccagga agtatgtttc ctgtttttat atttatccga tttcattgaa tagtcatagc
    24301 ctccttattc tttcatatgt tgaaattcca gtataaaaac tggaaggaac tgtacgtttt
    24361 ttagaataaa aattataagg gataagtagg ctgctgtcta taataagata tatttttcaa
    24421 ttctttatta aagattttat tgacaaaatg aatccgtttt ctatgatgga ggaggggtga
    24481 ataagttgtt gaagaaggaa attttatgtt acttagagaa ccagacagcc tttttcgatt
    24541 tagaacatat gaacgaggtc tttacagcac aaaggttagc tgatcatttt ggggtaaaaa
    24601 gaaacacagt cagtcattat ttgaaccagt taaatgatga gcaactacta gtcaaaatca
    24661 attctcgacc agtgatttat ttccacaaag aagcttttga aaaacaattt tttaagttac
    24721 gcacgaattt ttatttttct atcgatgatc tcaaagagga acagcctttt ttcgcgcaac
    24781 caaaagactt attctctttt atgatcggat acgacgccag tttgaaagaa agtatcgaac
    24841 aaatcaaaac agctctttac tatccagatg gcggattacc acttttgatt acaggcgaaa
    24901 gtggcacagg taaaagttat ttagttaatt tggtctatca gtattgtctg cttcatgatc
    24961 tgctagaaga ttctgcacca ttcatcactt ttaattgtgc acaatatgca gataatcctg
    25021 aacttttgac tagcaatttg tttggacatg ttaagggagc gtacactggt gcagaagaaa
    25081 ataaaaaagg ggcttttgaa gcagcagatg gtgggatctt gtttttagac gaggtacatc
    25141 gcttaacacc agaaggtcag gaaaaactgt tcacctatct tgatcaaggt gtgatttatc
    25201 gtatgggaga acctaatttg tcacgccgga tcaaaacacg tctctttttt gctacgactg
    25261 aagagattac tagtcatttc ttaacaactt tcattcgaag aatacctatc cgaatcgaac
    25321 tacctgcact taatcagcgt agtcgtaatg aacggctaga actgatttac tctttttttc
    25381 tcgaagaaca aagaaaaatg gggagccctt tgtcagtcag tggaccagct ttgtcacttt
    25441 taacaagtca gaaattatcc ggaaacatag gagagctgaa aaatatcgtc aaagtttcag
    25501 cagcaaaagc atatgctgaa cagcgtgaac agcctgaaat ccatgtcacg atccatcatt
    25561 tgcaaaaaga actacttgcg cagcctatta ctaaaaatac agcacagcaa ggaatctata
    25621 ttacgcaaga ccagacctta gagcaattaa tggagaagca acagcccgaa cagcagcgaa
    25681 tcgttaaaag ttttgagcaa atcctaattg atttcaagaa aaataactgt ctgctatatt
    25741 cttgcgaagg aaaattaaag caagaagtga ttcaattatt tgattttttg ctgtttgaga
    25801 ccagtagaca agaaaaacac gagctgctgg tttattggac acaatctatc cgagagacct
    25861 ttcgacaaat ggaaactgcc tatcaaatca aattcgatgg aaacagtgtc tatgccttga
    25921 gttactatct ctatcagcga agcactatca aatggttacc ggaagaacat gatattatcc
    25981 aactaatcaa agaattagaa caacaagttt ctcagtctta tccatctagt tatcactatg
    26041 tccaacgaat tctggaatta agtaagatca aattagatat tgaagacaca agtatggatc
    26101 ggattttact gacgatctat ctaaaaaaag cgaaatggtc aaaagaaaaa cgactgccaa
    26161 aagcgatgat tgctgctcac ggttatgcaa ctgctagcag tatggcaaat gtagtaaatc
    26221 gtttattaca agaggatcta tttgaatcat ttgatatgcc actagatgtc acaccacagc
    26281 agattgcttc agaaatcctt gattattgcg aaaacagcga tgtttcaaat ggattgatca
    26341 tattagtaga catgggatct ctgaaagaaa tccatcagtt ttttaaaaaa cagttatccg
    26401 taccgctttt gattttgaat aatgtgacga cacctttagc aatcacagta ggggaatgcc
    26461 tgcaaaaaaa tgtatcatta gaagagatag cagaagagac tgttcgacag atccagccag
    26521 aatggcgact gctctatcca gaggaaaaca aacccaaagc actcattact acttgcttca
    26581 ctggaatcgg tacggcggtc cacttaagtg aactgctaga aaaaagctta cctacggctt
    26641 gtcagttgaa aatcatccca tatgaatatc agcaattaaa agataagaaa aacagtgacc
    26701 cattattttc catatacgaa gtcgtaggaa tgattggcac cacagatcct gatatcacca
    26761 atatcgacta tctttcatta gaagacctca tctcggggga aaagatgtct gtactagctg
    26821 aatggttgga cactactatg aatgcttcag agaaggaaat attcaatcag cgcatcattc
    26881 gtaatttttc attggaaaaa gtactggatt ccgtgactat tctagataca gagaaggtga
    26941 tgggagaaat cgatcatttt atgagagaat tagaggtgca gttgaatcga agcatcagca
    27001 atcccaaaaa attagcgttg tatgtccatg tgagctgtct cattgaacga ttgatccgac
    27061 aaatgccaat cgaaacctat caaggattag agaaatggaa gcagtgtcaa aaagaagggt
    27121 tatctgctat taaatctgcg tttagtgtca ttgaagagca ttatagtgtc atgatcccca
    27181 attctgagat tgcctatatc tatgatattt tgagtgaaga tacagagttt ctctcgatag
    27241 aagaagaatt ttgaacataa gcaagttgtt gccactaatt ttggcatgca acttgctttt
    27301 ttagtatgtg taagtgaaaa gaggagatga aaaagtggat agagaaatta tcttagcttc
    27361 ccatggaaaa tttgcttcag ggatattaga ttcattagag ctgatctatg ggaaaaatca
    27421 ttctattact gtattcgatt gctatactga tgagaatttt gatttagcgg aaacagtaag
    27481 gcagcttttt atgaggtaca aagataaaga aatcattgtt ctgacggatc tttttggcgg
    27541 aagtgtcaac aacgaattct tacaatatat caatcgggat catgtctatc tcgttgccgg
    27601 attgaatttg ccactattga ttgagctagt atctcggttg gacgctgaag tagagacaac
    27661 tgttttgatc cagcaggtgc taactgattc aaaaaaaatg atccagtttt gtaacgagcg
    27721 gctcaatcag aaaatagaag aagacgaatt ttaggaggaa gaaaaatgat tgtattgaca
    27781 agagtcgacc atcggttatt acacggacaa gtagcttttt catggacaca aacaataggc
    27841 gcagactgta ttttgattgc taatgatgat gtacctacga atgagatacg aaagacaacg
    27901 atcaaattag ccaagccaca aggagtcaaa ctagtgatca aatcaattga tgactcgatt
    27961 gccgcgttga aaagcggggt gacagataaa tataagttat tcatcgtagt ggaatcgatc
    28021 gaggatgcat ataagctggc agaagcgtat ccagaaatca aaaccatcaa cttaggaggg
    28081 atcaaggcaa aacctggtac tcgcagcatc ggaaaagcgg taaatatttt accagaagag
    28141 gaggaacgct tgaaacgatt aattgacaaa caaatagaag tagaaatccg tcaagtacca
    28201 gcagataaaa aagtggatgt aagagaagtt ttgtaagaaa ggaagaacct caatgattgt
    28261 acaagcagtc ttattaggaa ttgttgcatt tgtcgcacaa tcagaatatg cactagggac
    28321 atcgttgctt tctcgtccga ttgtgacggg gctgtttaca ggaatcgtgt taggtgatgt
    28381 aaaaactggg atcattatgg gcgcaacttt agagttagca tttatcggat cgttctcagt
    28441 aggtgcttcg attccacctg atgttgtgac cggtgggatt ttagggacgg cttttgctat
    28501 tacagctgga gccggtacag aaaccgcgct tttactaggt ttgccgattg ctacgttgac
    28561 attgatattg aaaaatattt acttagggct tttgattcca attatgaacc ataaagcaga
    28621 caattatgca gaagaaggaa attataaagg agtcgagcat atgcacttgc ttgccggtat
    28681 cggtctttcc ttgatgcttg gtgttgtggt aatggtttct tatatggtgg gaagcaatac
    28741 gatcggaaat ctattaaata tgattcctga cttcgttcaa aaggggttgt cagtagctac
    28801 agggttgatt ccagctcttg gttttgcgat gcttgctcgt ttgctgatca acaaacaagt
    28861 tgcaccatat tttttcttag gttttgctat agcttcttac ttagagattc ctgtgaccgg
    28921 agtagctatt tttggtgcga ttttagcagt tgtggtagtc aatattatga atgtccgtca
    28981 actaccactt caaacaactg caggggaggt agaagaagat gaagaattct gagatcaaaa
    29041 acagcaaaat aacgaaaaaa gagctaaatc acgtattttg gcgttctttt caaatggagt
    29101 tttcttggaa ttatgaacgt cagatgaata tggcttatgt ttatgcaatg attccgattt
    29161 tgaaaaagtt atatcagtcg aaagaagaaa tggcagcagc tttgaaacgg catctagagt
    29221 tttttaacac gaccccacat atcgttacac tgattttagg aatcacggct gcaatggagg
    29281 aagaaaataa ggatgatcct gaatttgatg tgactgcgat cgatagtatc aaaacatctt
    29341 tgatgggacc tcttgcaggg ttaggagatt ctttcttttg gggaactttg cgattgattg
    29401 ccacaggtgt gggtacctct ttagccatgc aaggaaatat tttaggccct atcttgttca
    29461 ttttgatttt caatattccg cacattctgt ttcgctatct agcaacaggt tggggatatc
    29521 gcttaggaac gggttttttg aaaaagatcc aggcaaacgg tatgatggaa agtttgacat
    29581 taggcgcgtc tattattgga ctgatggtcg ttggagcaat gactgccacg atgatcacca
    29641 tcaatattcc tttaaaaatc ggttcaggag aaaatgctgt gactgttcaa agtatttttg
    29701 atgatatcgt tccaaatatc ttatgtcttg gagcatttgg catagtgttt tatctattga
    29761 agaaagaagt gaaaccatta acgatcttga tcggactagc tttctttgga atttttggtt
    29821 cgtggatagg gattttttaa aaaaggagca gagaaaatgt ttacgatgca agattatatc
    29881 tatgaagaaa aggaagtact aagtacgatc ttgaaaaaga atgatttttc gacaagagaa
    29941 catatgaaaa aaacagtgaa tttactgatc ttagcaacgg gttcatctta taacgcttgt
    30001 ttagcagcga agccagcatt ggaatcttat ggtgatctta ctgtcgatat tcaagaacct
    30061 ttttattttt tcaattatgg aaaactttct ccttcaatcg atactgtgat tgctgtgtca
    30121 caaagcggga aaagtgcttc tactgttgaa gcagtaaaaa tgatacaaaa acaagggtta
    30181 cctgttgttg ctatcacaaa tgacgtgcaa agtccacttg ctttagaagc tgcacaaatt
    30241 attgatttag gtgccggggt agaatcagta ggcttcgtta caaaaggcta ttctgcgact
    30301 gttttacagt tactactctt agggatagga attggaataa gtaaaaataa aatcagcaaa
    30361 aaaatagaac aagactacat gcaacagttg cgcaaaataa tcaaccattt accagcgatt
    30421 attcaaaaaa cggaagaatt ttttgatgga tatcaaagtt tatttcgttt agcacagcgt
    30481 ttcgtcacca ttggatatgg tccaaactgg ggaacagcta aagaagcaga gacgaaattg
    30541 actgaaacaa tccgcgttcc gtcacaagga tttgagttag aagcttatat gcacggccca
    30601 tacctggagg cagatgcttc gcatttgcta ttctttattg aaggggaaag tgtaaataag
    30661 gaacgttcgc aaaagttgca aagatatatg agtcggtacg ttggagagac tctcaccatt
    30721 accacaaaaa aagcaagaaa cgagaaaaca cttggattag caatagaatg tgatgaatat
    30781 ctgtctgtat tagcgcttgt cgttccgttt caactattcg cttataaaac cgcagtagct
    30841 aaaggtattg acttgaacaa aaagattttt gaagactttg atacagtctt gaaaagtaaa
    30901 ttataagagg tggaaatcat gctgaaattc aatgaagaag aacaaatcaa agcaataaaa
    30961 ggcgcactag ctttacgtcc gcaagtagaa gaaatcatcg ataaacttta tgcggaaaaa
    31021 tttgacgctg tctattatct aggaatcggt ggaacgtatg cttcctcgat gcaagctgtc
    31081 acttatatga atgggaaaag caacttgcct gtctttgtac agcatgctgc agaatattac
    31141 actactggaa acaaaagatt aacaaaagat tctatcgtta ttttgtcctc tgttaccggt
    31201 acaactcaag aagtagtgaa agcagtagaa caaatcaaga aagtaggagc gacactgatt
    31261 ggatttatcg ataaagcgaa cagtaagttg tctcagctat gcgattttgt ggtcacttat
    31321 ccagctcctg gaacagaaca aatcaaattt tttatggcag cagatcgatt gatgtatttg
    31381 aatggagaat tcgaagctta ttcagaatac tatgaacagc tcgaacgtta tttaccaaca
    31441 gggttagtgg aagcagagaa aaaagcagat gcatttggct tatcatttgc agaaaaacat
    31501 cgacgtgata gtatgcatta ttttattgga gcagggaatc aatggggagc tgtttattca
    31561 tatgccatgt gttactggga agaacaaagc tggcttccat cgaaatctat ccatgctgcc
    31621 gagtttcttc acgggacgtt agagatcgta gaagaaacaa ccccagtcac attattttta
    31681 ggcgaagatg aacagagagt gttatctgaa cgtgtggcta aacttttgcc aaaaatttgc
    31741 agcaattata cattgataga cacaaaagac tatccagtag aaggtatcag tgaaaaatat
    31801 cgcggacgtg ttttgtcttt cttattgatg catgtagtga cacaacgcat cgatgctcat
    31861 gtggagcagt tgaactgcca tccattagag atacgccgct actatcgtca gtttgattat
    31921 taggatagac tggataaaaa gaatataaaa aataaagaga gcagcgataa ctgctccctt
    31981 tattttttta aaatattggc atcaattacg ttataaaaca cattttttgc attatctaca
    32041 gttcaactta taatctgttt aatgggacat gtgggtgcca accatttttt gttatgcaat
    32101 agtactattt agttgttgca tggatccgta gtaaaagtcc aagtacaacg agttgcgcca
    32161 gtttacatag cgttttgtat ccagaatgtt gactaaaaca aaagttccta tgtcaaccgt
    32221 caacagagac aatctgtccg ttgcaggacc tgacagattt agaaatgttc aatctgtctc
    32281 ttatgtattt taaatcaata ctcactagga gaagtttcct aacctcctaa tagtaatgct
    32341 ggtagtaaca ttgtcaaaac tgcttcctct taggaacaag caaagcataa cgagtgtaaa
    32401 aataaaatgt agactattgt aacatatcat tgattatttc aagtaaaaac gataaaagaa
    32461 gtaaacaaac acttaaaaac aatggaaatt agtcccaact ttaagaaatg tatactataa
    32521 tggaaattat caattattta tttggaggaa tatccatgaa acaaaaaatc gcagttcttg
    32581 gtcctggatc ttggggcact gctttagcac aaacattggc agaaaacggg catgatgtcc
    32641 gtatttgggg aaatgtacct gaacagattg atgaaatcaa taagtatcat acaaatcagc
    32701 attttttacc tgatttgacg atcccagaat cgattatcgg atataaagaa ttggcagaag
    32761 cagtggataa cgcagatgct attttatttg ttgttccaac aaaagcgatt cgttcagtcg
    32821 cacaggaact tattggtaaa atgaatacta agccaatcat tatacatgca agtaaaggac
    32881 tagaacaaga tacgcataaa cgaatctcag aagttttggc tgaagaaatt ccagaagaaa
    32941 aaagacaggc aattgttgta ttatctggtc ctagccatgc tgaggaagtg gcagtacatg
    33001 atatcacaac aattacagct gcaagtattg atcaaaaagc agcagcctat gtacaaaaac
    33061 tgttcatgaa tgattatttc aggatttata caaataatga tgtgattggc gtagaaactg
    33121 gtgcagcact gaaaaatatc attgcaattg gtgccggcgc tatccatgga ttaggattcg
    33181 gagatgatgc aaaagcagca atcatgactc gaggattggc agaaatcagc cgtcttggtg
    33241 tcgcgatggg tgccaatcct ctgacattta tcggtttgag tggtgtgggg gacttgatcg
    33301 ttacttgtac aagtgttcat tctcgcaatt ggcgtgccgg taacttgtta ggacagggac
    33361 ataagctgga agaagttcta gaaaacatgg gaatggtcgt tgagggtgtg gcaacgacaa
    33421 aagcagcagt agagctagct caacagctag gtgttgagat gccaattact caaacaatct
    33481 ataatgtttt gtataatgga gaagatatca aaaaagcagc aaaagaaatc atgttacgtg
    33541 acggaaaaat ggagaatgaa ttttctcttc gttaaataga tgatcaatag ttaatcgtcg
    33601 tttaggagga acagcaagtg aaggtcaaaa aagcagtcat tcctgccgct gggctaggaa
    33661 cacgtttttt gccggcaaca aaagccatgg caaaagaaat gcttccaatc gtggataaac
    33721 caacgatcca gtttattgtg gaagaagcat tggattcggg aatcgaagac atcttgatcg
    33781 taacgggaaa agaaaaaaga cccattgaag atcactttga tgcaaatatc gaattggaaa
    33841 acaatttgcg ggaaaaggaa aaaacagaat tactcgcttt agttgaagaa acgactcaag
    33901 tcaatcttca cttcatccgt caatctcatc caagaggact gggggatgcc gtgcttcaag
    33961 caaaagcatt tataggaaat gaaccgtttg tcgtcatgct gggggatgat ttgatgaaag
    34021 atgatatccc attgactcaa caattgatga tggattatga agaaacacaa gcttccgctg
    34081 ttgccgtcat gcgtgtacca gaaaatgaaa catctaaata cggaattatt gatcctaaaa
    34141 cagatagcga aaagggtcgt tgcagagtaa aagggtttgt agaaaaacct gaaatgggaa
    34201 aagcaccaag taatttagcc attatcggac gttatctact gactcctaaa atatttgaga
    34261 tattagaaac tcaagaacca ggagcaggaa acgagataca gctaacggat gcacttcaga
    34321 ctcttaacca gacagaggcg gtctatgcga gagagtttaa aggaaaaaga tacgacgtag
    34381 gcgataagtt aggatatatg aagacaaata ttgaatatgg acttcaacat tcggaaattg
    34441 ggacttcatt aagtgcatat attatccagt tgagtaaaaa gctaagaaca gaaagttaac
    34501 tggaaataag tggcctgctg agaatgaaag gctatttgtt attaaagcgg cagcttgtgc
    34561 gtcatttgcg caactgtcgt tttagttttt tgactctaga tcagttgagt cgtggaaaac
    34621 gaaagataga aaaagacttt cgtgaataga ttcagaaaat attatgctaa tggtttaatt
    34681 tttttttaag ttgtataaaa gaaaatgatt acataagaga aatgaaagcc aagccagaag
    34741 attcatagta gaataaaaag gcgaattttt taattataaa aaaaggtgtg tgttcactat
    34801 gggaaaatta gtcgctgttg cacagtcgct gcttgatata ctcaagtggc tgatggaagg
    34861 aagcaattgg atatttgtgt tgccactatt gcttattagt ctatttatca tgtttcgcat
    34921 ggtcagaaaa aaagaaacgt ttctgatttt tatctggtat gcagcatccg ttggggttgc
    34981 taccttgatg gttgaattgg cgttaggtag ttgggaagct tgcgtatttg ctttattttt
    35041 tgctgtactg tatctaatca tttatatccc atatatgaaa agaaagtctc ggataggcag
    35101 aaaaggtaga catacaacta ctttttctag tacagattct ctcgaacaaa gtagaagaac
    35161 gagaagaaga cggtaatatt tagtaggtat acgcaaaaaa agataaaata atggataaac
    35221 tattgagatg agagat
//
LOCUS       DAXLPC010000020        35042 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.020, whole genome shotgun sequence.
ACCESSION   DAXLPC010000020 DAXLPC010000000
VERSION     DAXLPC010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35042
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.020"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(37..885)
                     /locus_tag="ACF3UE_000948"
     CDS             complement(37..885)
                     /locus_tag="ACF3UE_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3634401.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1109..3049)
                     /gene="thrS"
                     /locus_tag="ACF3UE_000949"
     CDS             complement(1109..3049)
                     /gene="thrS"
                     /locus_tag="ACF3UE_000949"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFD3634402.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3386..3565)
                     /locus_tag="ACF3UE_000950"
     CDS             complement(3386..3565)
                     /locus_tag="ACF3UE_000950"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFD3634403.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3612..5435)
                     /locus_tag="ACF3UE_000951"
     CDS             complement(3612..5435)
                     /locus_tag="ACF3UE_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD3634404.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5713..7992
                     /gene="helD"
                     /locus_tag="ACF3UE_000952"
     CDS             5713..7992
                     /gene="helD"
                     /locus_tag="ACF3UE_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFD3634405.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8085..8732)
                     /locus_tag="ACF3UE_000953"
     CDS             complement(8085..8732)
                     /locus_tag="ACF3UE_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634406.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8911..9630)
                     /locus_tag="ACF3UE_000954"
     CDS             complement(8911..9630)
                     /locus_tag="ACF3UE_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3634407.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9761..10912)
                     /locus_tag="ACF3UE_000955"
     CDS             complement(9761..10912)
                     /locus_tag="ACF3UE_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFD3634408.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11129..11869)
                     /locus_tag="ACF3UE_000956"
     CDS             complement(11129..11869)
                     /locus_tag="ACF3UE_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3634409.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11873..12196)
                     /gene="rsfS"
                     /locus_tag="ACF3UE_000957"
     CDS             complement(11873..12196)
                     /gene="rsfS"
                     /locus_tag="ACF3UE_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFD3634410.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12253..12846)
                     /gene="yqeK"
                     /locus_tag="ACF3UE_000958"
     CDS             complement(12253..12846)
                     /gene="yqeK"
                     /locus_tag="ACF3UE_000958"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFD3634411.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12830..13480)
                     /locus_tag="ACF3UE_000959"
     CDS             complement(12830..13480)
                     /locus_tag="ACF3UE_000959"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFD3634412.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13490..13801)
                     /gene="yhbY"
                     /locus_tag="ACF3UE_000960"
     CDS             complement(13490..13801)
                     /gene="yhbY"
                     /locus_tag="ACF3UE_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFD3634413.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13817..14926)
                     /gene="yqeH"
                     /locus_tag="ACF3UE_000961"
     CDS             complement(13817..14926)
                     /gene="yqeH"
                     /locus_tag="ACF3UE_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFD3634414.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNEIQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14923..15450)
                     /locus_tag="ACF3UE_000962"
     CDS             complement(14923..15450)
                     /locus_tag="ACF3UE_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFD3634415.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15630..16415)
                     /locus_tag="ACF3UE_000963"
     CDS             complement(15630..16415)
                     /locus_tag="ACF3UE_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFD3634416.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16408..17277)
                     /gene="accD"
                     /locus_tag="ACF3UE_000964"
     CDS             complement(16408..17277)
                     /gene="accD"
                     /locus_tag="ACF3UE_000964"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFD3634417.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17278..18657)
                     /locus_tag="ACF3UE_000965"
     CDS             complement(17278..18657)
                     /locus_tag="ACF3UE_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFD3634418.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18665..19084)
                     /gene="fabZ"
                     /locus_tag="ACF3UE_000966"
     CDS             complement(18665..19084)
                     /gene="fabZ"
                     /locus_tag="ACF3UE_000966"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFD3634419.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19109..19585)
                     /gene="accB"
                     /locus_tag="ACF3UE_000967"
     CDS             complement(19109..19585)
                     /gene="accB"
                     /locus_tag="ACF3UE_000967"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFD3634420.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19588..20823)
                     /gene="fabF"
                     /locus_tag="ACF3UE_000968"
     CDS             complement(19588..20823)
                     /gene="fabF"
                     /locus_tag="ACF3UE_000968"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFD3634421.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20842..21579)
                     /gene="fabG"
                     /locus_tag="ACF3UE_000969"
     CDS             complement(20842..21579)
                     /gene="fabG"
                     /locus_tag="ACF3UE_000969"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFD3634422.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21591..22508)
                     /gene="fabD"
                     /locus_tag="ACF3UE_000970"
     CDS             complement(21591..22508)
                     /gene="fabD"
                     /locus_tag="ACF3UE_000970"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFD3634423.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22615..22839)
                     /locus_tag="ACF3UE_000971"
     CDS             complement(22615..22839)
                     /locus_tag="ACF3UE_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFD3634424.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22892..23854)
                     /locus_tag="ACF3UE_000972"
     CDS             complement(22892..23854)
                     /locus_tag="ACF3UE_000972"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFD3634425.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23864..24304)
                     /locus_tag="ACF3UE_000973"
     CDS             complement(23864..24304)
                     /locus_tag="ACF3UE_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3634426.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24610..25575
                     /locus_tag="ACF3UE_000974"
     CDS             24610..25575
                     /locus_tag="ACF3UE_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFD3634427.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25632..25862)
                     /locus_tag="ACF3UE_000975"
     CDS             complement(25632..25862)
                     /locus_tag="ACF3UE_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFD3634428.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(25948..26835)
                     /locus_tag="ACF3UE_000976"
     CDS             complement(25948..26835)
                     /locus_tag="ACF3UE_000976"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD3634429.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(26924..28147)
                     /locus_tag="ACF3UE_000977"
     CDS             complement(26924..28147)
                     /locus_tag="ACF3UE_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFD3634430.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28164..29210)
                     /locus_tag="ACF3UE_000978"
     CDS             complement(28164..29210)
                     /locus_tag="ACF3UE_000978"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFD3634431.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(29374..31101)
                     /gene="ptsP"
                     /locus_tag="ACF3UE_000979"
     CDS             complement(29374..31101)
                     /gene="ptsP"
                     /locus_tag="ACF3UE_000979"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFD3634432.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(31101..31367)
                     /locus_tag="ACF3UE_000980"
     CDS             complement(31101..31367)
                     /locus_tag="ACF3UE_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFD3634433.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            31846..34080
                     /locus_tag="ACF3UE_000981"
     CDS             31846..34080
                     /locus_tag="ACF3UE_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3634434.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34228..34548
                     /locus_tag="ACF3UE_000982"
     CDS             34228..34548
                     /locus_tag="ACF3UE_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFD3634435.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(34753..34977)
                     /locus_tag="ACF3UE_000983"
     CDS             complement(34753..34977)
                     /locus_tag="ACF3UE_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFD3634436.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
BASE COUNT         9870 a         7575 c         6091 g        11506 t
ORIGIN      
        1 tattctaaaa aacttatata aaaaatagta aggtttttat ttcgaatcca taaaatattc
       61 ttggattgct tctcgtgttt ttttcacttt ttcgctaagc ttttcgtttt tagccatata
      121 gaaataaaaa atgatatcga tcgtagcaaa ttgggccaaa agtgaattag ttgccgcact
      181 tcgattcgtg atttcttttg gtctagatgt ttgtacgagt acatcggcta tcttgctaag
      241 cgggttattt ccaaattgcg tcaacgcaat gatttcgata ttcatgcttt tcgccagctc
      301 ggctaatgcg actacatctg cacttctacc tgagtttgaa acaagccaaa gcactttctt
      361 tttctcattg ctgacaagtt gcgggagcaa gacgtggata tctttttcaa aaatgattgg
      421 cttaccgaca cgagaccatt tttgcagaat atcttctact actaaagaag aggcgccaac
      481 cccatataaa aaaacagtct ctgccgattc caaacactct acgacttttt ggatcgtttc
      541 ttcttctaga atatctactg tttcttttat cgctacttgt gcattgttac caagtttgtt
      601 tttgatagag taaaaggact catttgcttc tatatcacta aaaccttcat cgattccagt
      661 ctgtagttct gttgaaatcg tgattttgaa gtccgtcaga ctttgaaaac cgattttttt
      721 ggaaaaacgt acaactgtcg gcgcactcaa cccggaagct tctgctaatt cattagctgt
      781 cattgtaggg accttctcaa tattaccgat aatgtagttg gccaactttt tttctgctga
      841 agaataatct tccatcatac tttcaatacg actaattacg ctcataagtt cctccaccct
      901 tttaatgata gtctatgtaa gtataccata tcagaccctt attcacggtc gtatactgga
      961 taaaaaacaa aaaaacaatc cgcccaacag aatatcttat cccatcaatc ccacagattc
     1021 tattgagcat ctgtgtcttt gaggaatacc tgttatctat tgttcggatt gctttctatc
     1081 tactactttt ttacaggaaa tttacctatt agttttctct gctgtaattt ttgacttctg
     1141 cttccatagc atcaataaag atattcaaat cttctacagc tgtttcttta cttccataac
     1201 gacgtacgtt cactgttgca tcttccaatt ccttgtctcc aacaactaat tggtaaggga
     1261 tcttttgtgt ttgagaggca cgtatcttat agcccatttt ttcattacga tcatcaactt
     1321 ctacacgcaa ccccttcatt tgcaaacgtt ctttgatttc ataagcataa tcgccatgtg
     1381 catcaacaga aacagggatg attgttgctt gtataggtgc caaccatgtt ggaaaagcgc
     1441 ctttgtatac ttctgttaaa taagcgacaa aacgttccat tgtagaaaca attccgcggt
     1501 ggataactac tggacgatgc gtattttccc cgtcttctcc aacatatgtc aaatcaaagc
     1561 gctctggcaa taagaagtct aattgtatag ttgataatgt ttcttctgta ccaagagctg
     1621 ttttgacttg aacatctagt tttggtccgt aaaaggctgc ctcgccttct gcttcaaagt
     1681 aatctagttc taattcatcc atagcggctt tcagcattgc ttgggctttt tcccacattg
     1741 cgtcatcatc aaaatattta tctgtattgt ttggatcgcg atagctcaag cggaaacgat
     1801 aatctgtaat attgaagtca gcatatactg ccaccatcaa ttcaagcgta cgtttaaatt
     1861 catctttgat ttgatcagga cgaacaaatg tatgaccatc attcaacgtc atttctcgta
     1921 cacgttgtaa acctgacaaa gcacctgatt tttcatagcg atgcatcatt cctaattcag
     1981 cgatacgaat tggtaattca cgataagaat ggatcgtgtt tttgtagacc atcatgtgat
     2041 gagggcagtt cattgggcga agaacaagca tttcgccatc tcccatatcc attggcggga
     2101 acatgtcttc ttgataatga tcccagtgtc cagatgtttt gtacaactca acatctccca
     2161 ttattggtgt atatacatgt tggtaaccta gactaacttc tttgtctacg atataacgtt
     2221 cgatcgtgcg tcggattgtt gccccttttg gaagccagaa tggcaaacca gaacctactt
     2281 ctggggaaac catgaacaag tcaagttctt ttcctagttt acgatggtct ctttcttttg
     2341 cttcttcacg gagacggata tattctttca aagctttctt gtcaaaaaag gctgtcccgt
     2401 atacacgttg catcatttga ttgtttgagt ttccacgcca ataagcacct gccactgata
     2461 ataatttaaa tacttgtata cggccagtgg atggaacatg tggtccacga cacaaatcga
     2521 tgaattcgcc ttgttgataa gcagtaatca cttcttcttc tggcaattca ctaatcagtt
     2581 ctactttgta cggatcactt gcaaaaattt ctaatgcttc ctgttttgaa agaacacggc
     2641 gttcgatcgg cagattttct ttgacgattt tcatcatttc tgcttcgatt gccggcaaat
     2701 cttctgcagt tacttggttt tgtccattat ctgtatcgta gtaaaaccct gaatcgatag
     2761 ctggtccaac gccaaagtgg atatttggat agaggcgacg catggcttgg gccatcaaat
     2821 gagctgctga atgacggact aagccaagtg catcttcatg gtctggtgtg atgatctcaa
     2881 tacttgcatc ttcctcgatt ggacgagtca aatcaacgag ttttccgttc actttaccag
     2941 ctaaagcttt ttttgctaag ctttttgaaa tgctttcagc aattgccaat gttgttgttc
     3001 cagactcaaa ttctttgact gcaccatctg gaaaagtaat ttttatcata atagtttcct
     3061 ccttgaaatg ttttgattga tcagatcatc aagctgaaaa acaaaaaaat cctagcatct
     3121 cttgaaaaga gatactagga cgaaaagttc gtggttccac ctaatgttca aacgcaaatg
     3181 cgttcctcaa gcgttgtaac ggtccgaccg cccttgcttc aacaagggtt tcgaaagtgg
     3241 tcatcctttg gttttctcct ggaaaagttt cagcctagct tttcctctct tatcgaagac
     3301 tctcaaattc agttggcttt ctcatcaatc aattatgtgt ttatttaacc actaataaat
     3361 agaaaaatca agtgggaaac taaacttatt ttttccattc cccatttaca ccgtatgttc
     3421 cttttttcat ctcattgatg atgacatgga tgtgttcttt tggtgcctgc gtgtttttat
     3481 gaacagcttc cgtgatatct ttcatcatat tttctaattg ttccggactg cgaccttcta
     3541 ctaattcgac atgtacgaat ggcataatgc tctctcctct ttctgatcgt tcttttttca
     3601 actcgattct atcatactat gtttgtcttg ggtactgaat caggaaaaat ggctggatct
     3661 ttttttgctc tcaaggcact caaaatagag accgtatcca cgacttcttg caaaacagct
     3721 ccgaataatg cggggattag tcccgtactt gcaattaaca tcaaaaaaat acaaataaag
     3781 atgccaatca gtacagactg tttcgctatt ctcatcgtat ctcttgaaat cactactgct
     3841 tttgctacac gcaagagatc atctttcaag atgaccgcat ctgcactttc actagcagct
     3901 gtagaaccat gagcccccat tgcaataccg atatctgcag cagcaagtgc tggtgcgtca
     3961 ttcacgccgt ctcctaccat cgcaacaggt ctttgatctt tagggatact ttctaaaatg
     4021 gtcagtttat cttgaggcaa gctacgggca tgtacagaat ctaattggac tttttctgca
     4081 atcgtttgag caatggcaga tccatccccg gtgatcatca tcaaattttt cacatcaagt
     4141 tttcttagct ccttgattgt ctttgctgct tctgggcgaa tctgatccga aaataggatc
     4201 gttcctgcaa aagatcgatc aattgttaca tagattgctg tattggacgt ttctatttct
     4261 tcagctgaaa caaaagaggc acgtccaatc tttacttcat gattattgac tactgcttgg
     4321 attccttgac cggtcacttc tttcagttga ctaacaggat acagttggct gtttttcacg
     4381 ttgttcacta acgaacgagc taagatatgg ctagattcct gttctgcact agctgcatac
     4441 agaagtagct cttctttttt tattccattg actggctgaa tcgcctctac ttccaatatc
     4501 cctttggtaa gcgttcctgt tttatcaaaa gcaatcgttt ttgtacgtgc gagcttttca
     4561 atcgttgttc cagtttttac aacgatcccg tttttacttg aacggctcat tcctgcaact
     4621 aaagcaatgg gcgcagctag aatcagtgga caaggtgatg ccactaccag tacctcagca
     4681 aatcgtaaag ggtcttttga gaaccaccaa gaaataccac cgatcaaata agcaatcaac
     4741 gtgaaaggga ctgcataacg atcagctaaa cggacaaatc gggcaggctt ttcttttgat
     4801 tcttcgacta gtttaataat catttgatac tggctgtctg cggcacgttt ttcagcgatc
     4861 atttggatcg atccgtctcc atttaaagac cctgacataa tctgatctcc aggtttcttg
     4921 gtttccgggc gggactcacc tgtcaaagaa gattcatcga ccgaagattc tcctttggtc
     4981 actcgaccat ctgcgggtac aagttcgcca ggcttgacta gtaactggtc atcaatattt
     5041 atttcatcga ttactatatc ctgcaatttt ccttctttga atcgatgggc aattcttggg
     5101 gtgttatcta acaaagactg cagttcttta cccgctcgtt tattcgcgta atcctctaga
     5161 ctatctccgc ccgtaagcat gatcaatatc atcaaactag cccagtattc tttgacggct
     5221 aatgttgcaa ggattgcggt aatcgctaat acatctacgc catatcttcc tgaacgtaac
     5281 gtcttgatca tttccaaaaa catcaagaag gcgagaatcc ctccagtaaa tgcgacaatc
     5341 gcaaatgcaa gggccggctg gtgaaaaaca aattcactta ataaagctat cccaccaata
     5401 agcaaagtaa gtaaaaattt tttgaaatgt gtcattgttt tttctcctct tttatgtgac
     5461 ttagagaggt tagtaataaa tttccagctg cctctttcat cttaagcata gtccttgact
     5521 agcacttttt aaaacaatag gccttaattg aaaacaacta tcactatcag cgtttccaaa
     5581 attcatcagt tctacaaaca aaaatattca gcaaggatta ctttttcgat tcatcagtta
     5641 aaaagtacct tttttcgaaa aactatgcta tacttttaat tcgttattta cggcggaagg
     5701 agcaaacatg cgatgaatga gaaacaacta gaacaaacgc acgtggatga aacgatcgaa
     5761 ctaatccaga tcgaacaaaa tatgctggat acaaaacaac aagaattgac tcaggaaatg
     5821 aatcattcga caaaagacac agctaatcac aagattcgag ctggttccaa tgaagctttt
     5881 tatgaatctg ctgttgaata tcgccaacat gagcaggaat tgcttttgaa ataccatact
     5941 cttgaagcac agcaaaaacg cctgcaaacg ttgtctgtca tgaaagatag tccttatttt
     6001 gcccgtatcg actttaaaga agaccgtgaa acagaaacat tatatctagg tatcgcttct
     6061 ttaagagatc tggcagaaga aacaatcgtt attgactggc gcgcaccaat tgccaatctt
     6121 tattatgaag gtgagattgg tcccgcattt tatgaaactg aaacagatag aatagatgtc
     6181 gatctgcagt tgaaacgaca atttaaaatc caagaaggac gtattttatc tatggtagat
     6241 acgtcggaag taatcaatga tgactttttg ctagagatat tggatgaatc atcaagcaac
     6301 catatgaaaa acatcgtctc tacgatacaa aaagcacaaa atgcaatcat tcgggacaca
     6361 acaagtaaag taatgctgat tgaaggaatc gccggaagtg gaaagacatc cgctttgctt
     6421 caacgtattg cttttctgtt gtatcataat cgcaagtggc tcgaggctga aaacgttctt
     6481 ctattttcac ccaaccattt gttttctgat tacatctcga ctgtattgcc ttcattaggt
     6541 gaaagcggcg tgcctacaca gacattcaaa aattatttgg tgcagctgct gccagagttt
     6601 tctttactag atgaacagca acaagaaagt ggttttttgc taggggaaaa agatccgata
     6661 caagtgatga aaagcggatt gaccttagtc gatcagattg atcgctatat ccaaggcatc
     6721 acaaactacg gtcccttgtt ccgtgatatg aaaataaatg gccgtacgat cctatcaaag
     6781 gaatcgattc gccaatggta taaagaaaca aatgaacaat tacctttaca tcatagactt
     6841 tctctattac aaacgaagct cctgaaaaaa ttaggcggtc tgcaaaaaga cgaaacacgt
     6901 cagcaatggg tcaaagatct ggcggaagaa cagctccaag aactatacgc aacagatcca
     6961 aatcttgaat atacagaaca aaaggagcgt tcattacgta aaaaactggc caaccaaatc
     7021 gtacgtaaaa gattccgtcg aatccatcga gggatcatga attatcaatt tgtcaatata
     7081 acgaaacaat atctccactt tctacaaact gtgccacttt ctcttctaac acgacataaa
     7141 atcagcgaga ccaggtggca ggaacatttg acaactgttc gtacacactt gcgtcaaaga
     7201 gaattgcgtc aagaggatgc tgtactattc tttttactga tgcgccgaac atatccagtg
     7261 acggttacac acaaagctcg ctatatcttt attgatgaaa tgcaggattt cgcaccatca
     7321 caagtggcat tgctgcaagc cttgttccca aaagcaaatt tgactttctg tggagatcta
     7381 aatcaaaatg tctttggaaa tgaaacgatc gttggatcat tggaagacct tttcgtggac
     7441 cgtgaagtca ctcgtttcca attaacgaca agctatcgct ccacaaaaga aatcactgat
     7501 tttgctaatc attttattgt gaaagaacat caagtagaaa caacagcaag aaaaggagac
     7561 cttcctttgc tcatccaagg aacaacagat gatatcaaat tgaattggtt agcagatacc
     7621 attcgaacga ctcagggaaa agcccggtat tggcgtacag caatcatagc taaaacacaa
     7681 gaagaatgcg aagctcttta tgctcaactg ccagacgagt tgaaacaaca agtccagctg
     7741 attttaaatg agagtgactt tatgaagcgt tccattattt tacttccagc ctttttagca
     7801 aaaggtctgg agtttgaccg agttttcttg tgggatgtag atgcagaaca tttttcttct
     7861 cagcaagaca aattgatcct ttacaccatg tgtacacgtg cgatgcatga attgaccctt
     7921 tttacctcca ataatgaaag tcctttgtta aacaatatgg atatttcatc ttatgagaaa
     7981 aaagtactgt aagtaaaaag acaactgcta tcattaatgt tagcagttgt ctttttattt
     8041 acaataataa ttgcagaaaa agtaattcaa tcatttaagg tcatttattc tatatataaa
     8101 tccaaatctg tttcaggata ttttaatttg acaagcgaaa taatcatttt cagttcttcc
     8161 atgttttctg gatattctgg gtcaaatacc ttgctatgac ggccaatccc gccattgtcg
     8221 atcaatcggt aaattcgatt ccattcaatg aattggtcaa ttgattggaa attgctgatt
     8281 ggatagccgc cacaatccaa aatctctgat acacgaaatg ctaggtatgc actatcgatc
     8341 actttatttt ttttcgtgtc tatcttctca tttctttcga taagaatttt ttcaggacga
     8401 tgtttcaagc tccactctaa tagtagaaag aaagcctcca tccgatactc ttcttcaaat
     8461 aaccgaaagg ctgaatcaga acgacgaaaa agcagcggaa tcagataatt ttgtctataa
     8521 atcagcattg gtgcgcggtc caccatacac tctaaataac ggttcagata ccctgtaccg
     8581 acatagtttc ctaatcgata gccttcaacg ccgaatcttg cgtatttttg cgctaatttt
     8641 gaacaatcag ttacgttcac agctaactct tctactttgc ggtaaccgct taagatacgt
     8701 tcaaaaggtt ctaaagtgat ttttgcttcc atattcttcc ccgtccatct tccacatact
     8761 tcatatcatt tcacatgata cttatgctct catcatacca caggttgaat tagaaaagaa
     8821 aataaatcac acaaaaaagc aagacaatct gttagtgaga ttgtcttgct tttcgaaaaa
     8881 gactgaatac ttttcgttaa aactggttgc ttagtcttct aatgccacat tatggaacac
     8941 atgctgtaca tcttctagat cttccagtgc atcaatcatt ttttcaaatg tttcttgatc
     9001 ttctggagat agtgttacct cgttttgagg gatcatttgg atctcagcga ttgaaaaatc
     9061 agtgattcct ttttctttta atgcttcttg tatactatgg aaatccgcta cttcaccgta
     9121 aacgatgatt tgtccttctt cttccattac atcgcgaaca tcgatgtctt tttccattag
     9181 gtattcaagg atctcgtcag cgtcttctcc tgcaaaagca aagattgctg tattgtcaaa
     9241 catgtaagaa accgctccgg aaacacccat gttcccgcca tttttcccaa atgctgcccg
     9301 tacgtctgct gctgttcgat tcacattgtt cgtcaatgta tcaacaatca ccattgagcc
     9361 gcttggtcca aatccttcat agcgcaattc agagtatgtt tcatctcctg caccttttgc
     9421 tttttcgatt gctcggtcaa taatatgttt tggtacatta taagttttag cgcgatcaat
     9481 gacgaaacgt agtttttggt ttgcatgcgg atcaggatca cctgattttg ctgccgcgta
     9541 gatttcaatc ccaaattttg cataaatccg gctattatta gcatctttag cagttttctt
     9601 tgctacgata tttgcccatt tacgtcccat attttcactt cgctttctga tttgatagtt
     9661 tcataacgca aaaacgtcct gttccattat acttgtgaat cacgattctg tgaagctttt
     9721 tttctttctt ccttcattct tctcattttt agtcaattat ctatactcgg attgggattt
     9781 gcccgaaatt ctgttccgga atattgcctc ccaattgata gatttgatca cttctaacta
     9841 acagttccgc ttcttgtgcc tctttttttc cgattcggga ataaatagaa atctcttttt
     9901 tttcttttaa gaatcttctt ccagcatcgg taaatccaag tagtcgaaga taatttttat
     9961 tttgttggac aggaatctct tgctttttga tattcagcaa gacataacaa gataatcgtt
    10021 ggatccgtgt ccatgtatat ctttttgttt ttacctttga cacaaaatcc tcaaaactat
    10081 cagcagttgc agctgctgtt ttcatgcgcg attctattcc ttcggtcatc tgatagatat
    10141 ctgtcagttc cagcaaagta gaagataaca accgataacg caaatacggc caataagatt
    10201 cccaagtctg cagcgaacaa gttgaaagat cttcttctgt ctgaggcggc acaagtccag
    10261 ctattctttt tccttcttct aacgcatggc gaatggctgt tgcactggct atcctctgat
    10321 ctgtgatgat tttttcatga tagcctgcac ttttacgtcg gatcggatgt aattccatag
    10381 ggtggacata cttggcattt tcctttgcat aacttaatcc caagatatga tttggcgaag
    10441 aaaaatcaag cgtaatatcg ggatacagac tgcgaaaaac ctcagtcatt ttttgcggat
    10501 aactatacgt ttgatcagac agttcttgaa atgcctcttc tatcctatct tgattctctt
    10561 ggacaaagcg tccgaaactg ctgtaatcaa acgaagtctc ttcttctgtt ccaaaacaca
    10621 aactgtcaca gtccagtgtt tgcaagattt ttactgcacc tttagcaaaa tagtcagctg
    10681 actgaaccgc ccattcgacg ggaagctcca ctactaaatc cacaccattt tgtaaagctt
    10741 cattcgcgcg atgccattta tcgatgatag ccggttcgcc tctttgcaaa aaattcccgc
    10801 tcattacagc aatgacgacc tctgctcctg ttatttttcg tgccatttcc acatgatagc
    10861 gatgtccatt gtgaaaagga ttgtactcta cgataatccc gcagcttttc atgcgcatcc
    10921 tccttcatag ttatcgataa aaaagaaata gagacaagta aaaaaaggca aaaatcggaa
    10981 aaaatacccg aactatataa actattctcg caaacacaat acttctgcga cgaaaagctg
    11041 cactgcaaga gcaatgccta tatcgttcgg atatataatt tatgttgaag atttattctt
    11101 ttcttgttaa ctcgagcagg caaaaccgct agtctttgta tgctacaaag aaccagcgct
    11161 ttgatttctc tgatgctgct tcgtctgtaa aatcagaaaa tgcttcgact ttcgaaaagc
    11221 cgctgttttc cagcattctt aaataacttt ccaatggata ggtacgctct tgatgtagtt
    11281 catcttcacg aataaatcga ccagaccctt cttgttcttc aacgaaaaag gtaagaaaat
    11341 gttcgatgct gtgtttctcg cttcctggat aactatccca caaaaaagca aaattatccc
    11401 cttgataatg atagctatat tctggaaaaa cctcatctac ttgataggtg gagtgtacgt
    11461 caaataaaaa tcggccattt tcttctaacg cttgatagac ttcatcaaac acttgctgta
    11521 cctcttgtct atttttcata tagcacagcg aatcagaaaa acaggtaatt gcctgatatt
    11581 gtccgatttc tgataaatcg agcatattgc cttccacaaa ttggatcgat gcgtcttctt
    11641 catatgctcg ctggctggca atcatcaaca tctcttctga aaggtctaac cctgtcactt
    11701 tatatccatc ttttgcaaag gcaaccgcta atgctccagt accgcatgcc agttccaaaa
    11761 tattttttgt gtcttcttgt aaatgacgtt tcgaaaaagc taaccattgc tgataaagtg
    11821 tttcgtccat cacttcatcg taaatgaaag caaatgtttc ataagccata tgttaatcca
    11881 accattcact aagatcgact agcggagcat ctgaccatag tttttccaga ttatagaaat
    11941 ttcgttctgg cgcatggaaa acatgtacga tcacatctcc aagatcgatc aatacccatt
    12001 ttccgccttc ttttccttca atacgtttta cttcatattt gttttcttct tctttatcaa
    12061 tgatttcttc tgtaattgcg ttgatttgac gttcgctatt tgctgaacag atcatgaaat
    12121 aatctgccaa caaggaaaca tttcgaacgt ctaaagcgat aatgtcttct gcccgttttg
    12181 aatctgctgc ttcaatcgca atttttaatt gttctttact atctatgatg atttcctcct
    12241 aatatgagca gcttattttt ttgctaccca gtaattatat gtttcgattg tttttggata
    12301 aatctgttgt tcttgcgcaa gcaaatgggc caatgtatgt tttgtttcaa atgctacagc
    12361 ttcgtctaga tcagcccatg caatggctcg tgcatcttgt accccaggaa aatctcgacc
    12421 tggttcaata tagtctgcta cataaatgat tttgtcaagg agactcatct tagcagcccc
    12481 agtcgtatgc acccggattg catgaagaat ctctgcatcg gtgattccta attcccgctc
    12541 tacaaacgaa gcgccaacaa gaccatgcca gattgcatta ttataattca ataactccgg
    12601 atcaaaaccg tctcttacga ttaccatttt gaactcctca tctggtcgtt cttttgcata
    12661 atcatgtgtc aatgcagcaa tactagcttt ttcaggagaa gcaccgtatt ttttggcaag
    12721 agccacggct gtttcttcta ctccaagcac atgcttgaag cgttgttcgc tcattctcat
    12781 ctgtattttt tgcatcaggt tttctctaga ataagcagta tattcattac tatagtccat
    12841 attcatacaa cccttcattt tgaatataat caattacttt atctggaaca aggtagcgga
    12901 tagaacagcc ttctttgatc ttttgacgta ttttcgtgga actgatgtcg atctcaggta
    12961 catctaccca aattacagga tatggagtat ccgttgtgta tcctggtcga cgtataccca
    13021 caaagttgac catagaagtc agctcatcga ttttatacca ttttggcaaa tattctacca
    13081 tatccccacc gataataaag taataatctg tatccggatt gttttgcgtc aattccttca
    13141 tagtatcata ggtgtaactt ttcccaccac gagctaattc aatcgtttca atctgcaaaa
    13201 aaggattgtc ttccaccgct aattccaaca tgttgagtcg atgttttgca tcaatcgtct
    13261 gtttctcatc aacatgaggt ggctgataag aaggcatcaa aaatacgcgg tcaagaccta
    13321 aattccggcc agcttgttca gccatcacta aatgtgcaag gtgaacggga ttgaatgttc
    13381 cgcccaagat ccctacttgc tttttcttct ctaagaattg aggcatttct tcaggaaata
    13441 attgtgaacg aacaaatgtc ttagcttgcg tattcatcat ggtcactcct tatattgctt
    13501 ttacttcttt tgatagcctt tgatactttt cttttgtgga aggtttgtat aatacaataa
    13561 cacgtccaat gatttggacg atttcgcaat ctatttcttt ttctaatact tgagctgctt
    13621 cttctgcaat ctcatctgta ttttgaagta acgatacttt gatcagttct cttttttcta
    13681 aagcttcttc aatttgaacg atcattgctg aattgatccc accttttccg atttgaaaaa
    13741 tcggctgaag atgatgcgct ttgctacgta aaaaacgctt ttgttttcct cttaaactca
    13801 taattttcct tcttccttaa atcaatgctt tgcgtttcaa tacatctaca ccctttggcg
    13861 cccagcccgc aattactact ggcgctgtta cagtgatcca gcctagaccg gcaaaaacga
    13921 tgtctgtttt ttctttcaca gaaaactcaa aacgaacaag ctccggaaat gcctcgactt
    13981 catcaggacg aggaggctgt aataatccac ctacatgttt ttgataaaat tcgtctgctt
    14041 tttccagttt cgttcgatga atatttacat catttgacac ataagcaata aatgaagcac
    14101 gattgccgct gataaaatca aatcttgcaa gtccgcccaa gaaaagtgtt tgcccttcat
    14161 tcagctgata aactttaggt ttgatttctt ttaacggtgc aatgatccgc aaatcttttt
    14221 tacctaagta gtgcgccatt tgatggcgat ggataattcc cggtgtatca atcaaaaaat
    14281 gcccgtcatc taaaggaatc tcgattttat ccaaggtcgt tcctggaaac tgcgaagttg
    14341 tgattacatc ttgtactccc gctgtatttt tgatgatttg attgataagc gtcgattttc
    14401 cgacatttgt tactccgacg atatagacat cccgtccatc gcggtattct tcgatttttt
    14461 ctaatagttc cgtcatctca tgagatttct tagcactagt taataataca tctactggac
    14521 gaattcctgc ttcgtaagca cgttccttca tccattgtgt taatttagtt tttttcaatg
    14581 atttaggtaa tatatccact ttgttcccaa ctaaaagtac tggattgtca ccgacaaaac
    14641 ggtgtagtcc tgggattagt gaaccattga agtcaaaaat atccaccaca ttgacgatca
    14701 atgcatcttt ttgccctaat tcattcagta agcgcaaaaa gtcgtcatcc gtcaatgaga
    14761 catcttggat ctcattataa tggcgtaatc tgaaacaacg ctgacaatag acttccccgg
    14821 aagctaaacc tttttccaaa gccgtttgcg gcgtgtatcc taattcaccg ggtttgtttg
    14881 tttgtataac ggcaccacag ccgatacatt gtaattcttc tgtcattcga ttccacctcg
    14941 ccagcccata tcagggtgtt ttgctaatag ataggccata attctttttt cccaaaaacg
    15001 attaaattgt gtcttccaac tatctgttgc gataatgggt tttacaagga tgctacgtat
    15061 ccctgcacga ttggctccac gtatatcagt cataatctga tcgcctacca ttactatctc
    15121 atcatctgct aaatccaatt gtttctttgc tatgttgatc cctcttgcta aaggtttcat
    15181 tgctcgtgca acatacaaaa gatcaaattt ttcaatcgct cgcgcgacac gttttgaatt
    15241 attgtttgaa acaacaacaa cagggattcc tgcatttttc atttctaaaa tccaagtaag
    15301 caactcttct gttccatctg gattattcca tgcaatcaac gtattgtcta aatcggtcaa
    15361 tactgctttg atgcctagat tctttaattg ggcaggtgta atctgataga tggcttctac
    15421 catccatgtt ggtttgtaat ttgaaaacat gctgtctcct catctgcaaa aaatgaagga
    15481 gcacataaag tactcctcaa ccccgtatta tactgcatat cagcaaaaaa aactacctct
    15541 atactcgttc gtctttcaga aaaagcattt ctttacaaaa tgaccaaaaa taaagattga
    15601 tcacagaaaa atttagaaac aaaaaacaac taatattggc ggaacctctt gtatcgtttt
    15661 tccagtaatt tatgctgatc taatcgaaca agttccgtca atctttcaat caacgctttt
    15721 ttcataatgt gtgcgacttt atatcgtggc aactgctcgc cgttgaacgt ttcaggaata
    15781 actcgatcaa cgattcctaa ctcgcgtagt tctggcgcag taattttcat caactcagct
    15841 gcttctgcgg cgcgactacc gtctttccac aaaatcgacg caaatccttc tggagaaagc
    15901 acagcataaa tcgtttcttc cagcatccag acttcatccg ctaaacctag agcaagggca
    15961 ccgccacttc caccttcacc aatgatgatg gcgatgatcg gtacctttaa atcagacatt
    16021 tcgagcagat ttctggcaat agcctctcct tcgccgcgct cttctgctcc tacaccgcaa
    16081 tatgcacctg ctgtattgat caaggtaatc accggtctat tgaacttttc cgcttgtttc
    16141 atcagtcgta aagcttttcg atagccttca ggatggggag aaccaaaatt tctgcggata
    16201 ttttcctgca gatcccgtcc tttttgaata ccgatcactg ttaccggttt gccatctaat
    16261 cgagcgattc caccaacaat cgcttcgtca tctgcaaata aacgatcacc atggcattcc
    16321 tcgaaagaat cgaagatctc ttcaaaaaaa tccaagcttg tccatcgttc tttagctctt
    16381 gctaactgaa cgacatcatg tgctgtctta tccacgatct atccatcctt tctgtgtatg
    16441 caattcaaga agcgtatgga ttttctgttt caattccatg cggggaacaa tctgatcgac
    16501 aaaaccatga gataataaga attcagcctt ttggaaatct tctggaagtt cctgcttgat
    16561 cgtctgttcg atgacgcgtc ttccagcaaa accgatcaag ctttggggtt ctgctagaat
    16621 aatatcgcct tccattgcaa aactggcagt tactcctccg gtcgtcgggt ccgttaaaac
    16681 agttagataa aaaagacctt cattgctatg ccgtttgaca gcagcagaga tttttgccat
    16741 ctgcattaga gaaaagattc cttcttgcat ccgtgcgcca cctgaagctg tgaacaagac
    16801 gactggaaga ctttcctttg ttgctcgttc gaataatctg gtgatctttt ctccgacaat
    16861 cgttcccata cttcccatga taaaattagg atccatcact ccaataatga agggaatccc
    16921 ctgaatggtt gctttaccag tgaggactgc ttcatgaagt cctgttttat cttgcatttt
    16981 tttaattttt tccgtatatt cgggaaatgc tagcggatct ttggttacaa gatccgtatc
    17041 ccattcttca aaactttttt catcaataat caaagctaga cgctgccatg caccgattcg
    17101 aaaagcgtat ccgcaatgag ggcatacttt ttcttcaccg atgtctttcg tataaaggat
    17161 atgtttgcaa tttggacact ttgcccacat gttatcagga acagatggcg agttagcagg
    17221 tttgctctct ctattaggat tgatccgaat atatttcttt ttcttaaaca gagccatcta
    17281 tgcgcctcct atctccgttt ctggtgtcca attcggtaaa aattcttctt gtaaaaatgc
    17341 tgtgctgtaa tcacctgcta tgactgcagg atgactaatc aaatccatct gaaattctgc
    17401 gttcgtgatg attccttctg tgataaattc acttaaggct cgctgcatct tcattaatgc
    17461 ttcaaaacgc gtatttccat ggacgattat ttttgcaatc attgaatcat aatatggcgg
    17521 gatcgtatat cccgggtaaa ctgcactgtc tactcgcagt cccatcccac ctgctggaag
    17581 cagtaagttt tggatcttcc ctggagaagg agcaaaatgg aaagcaggat tttctgcatt
    17641 aatccggcat tcgattgcgt gtccttggaa tactacttct tcttgacaca cattcaaagg
    17701 ctcaccggct gctatctcca cctgtttttt tactaaatcg attcctgtga ccatttctgt
    17761 tactggatgt tccacttgga ttcgagtatt catttccatg aaataaaaat cgccttcttc
    17821 atccatcaga aactcgatcg ttccggcatt ttcataattg actgctttag ctgctcgaac
    17881 agcagcgtct cctagtgctt ctctttttgt ttgtgagatc actacagaag gagattcttc
    17941 cagtactttt tgattgttgc gttgtaaaga acaatctcgc tcgcctaaat gaatgacatg
    18001 accaaatcga tcacctaaga tctgaacttc tatatggcga gcaggataaa tgattttttc
    18061 caaatacata tcatcatttc caaatgccgc tgctgcttct tgctgagctg aagaaaaatg
    18121 ctgtgggagc tcttcttttg attgaacttt ccgaatgcct ttcccgccac cacctgcagc
    18181 tgctttcagc atcactggat aaccaattct gtctgctatt tccaatgctt cttctactgt
    18241 agataataca ccagtacttc ctggaatgac tgggacattt gcttcttgca tcaattgacg
    18301 cgcattgatc ttatttccca ttgcatcgat cgttgcactt ttaggaccaa taaatgtgat
    18361 attgcactct tcacacatgg aggcaaatcg gctattttca gataaaaaac caaatcctgg
    18421 atgaattgct tcggcttttg tcacgattgc agcgctcagt acttcctgaa cattcagata
    18481 tgaatcaacg gcttttgccg ggccaatgca gattgcttca tctgctaact gtgtatgaag
    18541 tgcttcggca tctgcttctg aatatatcgc tacggtttgg atccctagtt cgcggcatgc
    18601 acgaatgata cgtacagcga tttcaccgcg gttagctatc aatactttag aaaacatatt
    18661 tcacctatcc aatcataaag gttaattccg cttcggctac ttttttaccg tctactttag
    18721 cgattccttt gcctattccg gctgaagctt tcactttcaa tatctcaact tcaaggtata
    18781 aggtatctcc cggtgtaact ttcttacgga attttgcttt gtccaatccg ccgaaataag
    18841 ccgtctttcc cttgaattgt tcaagagaaa gtaatgcaac tgctcctgct tgagccattg
    18901 cttcaacaat caatacccct ggcataacag gttcttctgg aaaatgtcct tgaaaaaagg
    18961 gctcattgat cgttacattt ttcttagcaa cgatccgttc tccttcaacc atttcttcca
    19021 ctcgatcaat caaaagcatt ggataacgat gtggaatgat ttcttttatt tcttgtatgt
    19081 tcattgtttt ccctctttcc tgctttgctt atttttgctg aatcctaaag agtggctgtc
    19141 catattcgac aactgactcg ttttctacaa ggatttctgt gatcactccg tcggcctcac
    19201 tagttatctc attcatcagt ttcatcgctt caataatgca gataacttct cctttggcaa
    19261 cttgatcacc tacttttttg aaagctggtt tgtcgggcgc tggttgcaga taaacgattc
    19321 ccacgattgg cgaaacaacc tcgattccat caaatactgc cgattctttt tctttcatta
    19381 tttctggagc agttgttgct tgttcagata tgacattgac tggctccgaa actggcaacg
    19441 tttcgtttgt ttgaaccata ttcatgcctc gacttgtttt atttttattc atatacaatt
    19501 caaattgacc ttcacgcaaa tcgaattccg ttagcgagga ttgatcaaat tgactgacta
    19561 attctctgat ttcattgata tccaaaatta ttcctcccag cgtttcatgc acagaaccgc
    19621 attatgtccg ccaaacccta atgaattact cattgcataa gtaaaacttg caggtttgct
    19681 ttcgtttttg acaactgtca agtcaatctc aggatcttgt ttttctacat tgatcgtagg
    19741 tgggataaat tgatgttcta atgccagcaa agttgccaag gcttcgatcc cgccggctgc
    19801 tcccaataaa tgtccagtca tcgatttcgt gctgctgacg taagtatctc tgaaattttc
    19861 acctaatgcg atttggattg cttttgcttc tgcctggtca ttggctggtg tacttgttcc
    19921 gtgagcattg atatatccga cttgttccgg ctgtacacca gcttcttcca tcgcaagctt
    19981 cattgcttta gatgcaccag aaccatctgg agtaggagct gtcatatggt aagcgtcaca
    20041 gtttgcaccg tatccaacga tttctccata gattttggca ccgcgagctt gtgcatgttc
    20101 taaagattca agaactagaa cgcctgctcc ttcacccatc acaaaaccat tccgattttc
    20161 gtcaaacgga atcgaaccac gattaggatc agttgattct gagagtgctg ttaaagctgc
    20221 aaatccagca atccccatct cacaaatcgt tgcttctgtt cctccagcaa gaatgacatc
    20281 agaatagcca tgtttgatgt tacggaatgc ttccccaatt gaattcgttc cgctagcaca
    20341 agctgttacg atagctgtac aaataccttt tgcacctaca cgcaaagcaa tatttccagc
    20401 tgccatgttg gcaatcgcca ttggtacgaa cattggagaa actcgttttg cacctttttc
    20461 atgtagacga ataacttggt tttcgattgt tggaagacca ccgatcccag atccgatgat
    20521 gacgccaaac cggtcttgat tcattttttc tttatctaaa ccgctcatct ccattgcttc
    20581 taaagcagcg tagattccat agatcgaaaa catatccatt cgtttgctat cttttttaat
    20641 aaaatattta tcgtaaggga aatctttgac ttcacccgct aaggtaatcc ctgtttctga
    20701 agcatcaaat ttagtgatcg gtgcgatgcc attcgtcccc tcttttaagc tattcaaaaa
    20761 gctgtctgcg tcatttccaa taggtgaagt gactccatag ccagtaatta ccactcgatt
    20821 catttgtttg ctctcctttt cttatccgtg catgaccaat ccgccatcga cattgatgac
    20881 ttgtccggtg atatatggat tttgtgctaa gaaaactgct gtttgtgcaa tatcttctac
    20941 ttgtccgaaa cgctgcatcg gaatttgctt ttccgcttgt tccttgactt tgtctgctaa
    21001 aacttccgtc atatcagttg tgatgaatcc tggcgcaatg gcattacatg taatgcctct
    21061 agttgcagct tctcgtgcca cagattttgt taatcctact acgccagctt tactagctgc
    21121 ataatttgct tgaccaatat ttccaatcaa cccagataca ctagagagat taatgatggc
    21181 cccttctcgc tgcttcatca tttttttcaa tacgtgctgc gtcatattga aggttccaat
    21241 caaattgata tccagacatt ttttgaaatc ttctgcatcc attcgcatca caagtttgtc
    21301 atttgtgatt ccggcattgt ttactaacac atggatcgat ccaagctttt cttctgcttc
    21361 tttgatcatt tgtcccgctt tctcataatc agagatgtca ccggaaactc ctacgcattt
    21421 tacaccgaat gcttcgattt cttctatctt ttcttttgga atctctccgc gaccattcaa
    21481 aatgatattt gctccagctt ttgcaaaagc taaggccatc gctttgccga ttcctcttgt
    21541 actacctgtg ataaatacat tttttccttt tacatccata acgttcctcc ttatagtatt
    21601 gctattgttt catcaaatgt ctgcttattc tcaacacgca gaactggtat tgttttatcg
    21661 atttttttca taaatccgct taatactttt ccggggccga cttcgatgac ttgttcgatg
    21721 ccgattgttt ttaacttatg gatactctca tagaaacgaa caggttgcat gacttgctgt
    21781 tcaagtagtc ccgcgattgt ttctttcttc attatttccg ttgttgtgtt gcttatgata
    21841 ggaaaagaag gttcagagaa ttgaatctga cttaggtcct tcgccagttt ttttgctgcc
    21901 ggttctaaaa tagctgtatg aaaaggcccg ctgacattta gagggatcat tcttttgaac
    21961 cctttttctt ttaatagtaa aacagcttcg tctactgctt tttcttcgcc accaatcacg
    22021 atctgctgag gtgtattata atttgcagga gatacgatgc cgtacttgct agcttcatga
    22081 cagctttcct cgatcgtttc aatcggcgca ttcatcactg caaccatttt cccgcttcca
    22141 gctggggtag cttctgtcat ataagcgcct ctttttgcta ctaacgcaac tgcttcagtg
    22201 aaggatagcg cattactagc tactaatgcc gaatattctc ctaaactcag tcctaaagct
    22261 gcatctggga tgattccatg ctccttcaat aagcgataat acgcgatgct gactgttaga
    22321 atagctggct gtgtatattg cgtctgatcc aaacgttcat tttctgtaaa gcaaagttca
    22381 gccatatcgt agccgagaat ctcacttgct tcatcaaatg tctgctttac aacggcttct
    22441 tcatataaat cttttcccat accttgatat tgtgcacctt ggccactaaa taagaatgct
    22501 gttttcatgt ttttctccaa tatatccaga atatatgttt gattcttcct attcaaaaag
    22561 gccgagacat tcctatttca ggaaatgtcc cagcccccaa cctaatttta atgattatgc
    22621 agtttgtttt tctacgtaag tcactaaatc ttgaaccgtt ttgattccgt cttctgtttc
    22681 gattttcacg tcaaattcat cttcaatttc attgatgatt tggaataaat ccaagctgtc
    22741 agcttctaag tcttcttgga tgtcagtagt caatttgatt tcttcagttt cttttcctaa
    22801 ttcttctgcg atgatttctt gaattttttc gaataccata ataatatatt cctccgatat
    22861 tgtttgcttt ttatttttat aatttaacag tctacaactc catgagaata cttccccatg
    22921 ttaaacctcc gccatagcct gtaaatatta ctttctgctg ttttcctaag gtgatctttc
    22981 cactagaaac tgcttcatcc aataagatag ggatgcttgc agcagatgta ttcccatatt
    23041 tatccatatt ggtcaggaac ttttcttgcg gcatctttac ttttcgggca attttctcaa
    23101 taattctgag gtttgcctga tgcaaaagca gataatcaac tggtttgtct ttcatgactt
    23161 cttggatatt gtttgcaacg tctcgtacgg caaaatcaaa aatatctctg ccagtcattt
    23221 gcaaataata cgaaccttct gaatcttctg aatagaacgg atttttattt tgctggtagc
    23281 cagcggtcaa tgagctactt ctggtaccgt cagctgctaa tttttctttc agcaattttt
    23341 tctgtggatt cgcttctaag agaatcccac ctgctccatc gccaaacaac acagcagtcg
    23401 tacgatcaga ccaatcgatt agcttagata gtgtttcacc accaatcacc agtcccttag
    23461 ttgagccgca gcggatcatt ttttcagcca tgcttaacgc ataaacaaat cctgagcacg
    23521 cagcactgat atcaaaagcg atagcatgag ttgctcccaa tttcccttgt acttgtgctg
    23581 ctacagatgg tgtcgtgtaa tcgggcgaca ttgttgctac taaaataaaa tccaaatctt
    23641 tagggtttag atttttctgt tttatcaatt tttccgccac taaaatgcat aaatcagaag
    23701 tctcctgatt tgttacacat cttcgttcac gaatacccgt ccttgacgaa atccattcat
    23761 cagaggtatc catcatcttg gaaagatcat tattagtaat aatcttttca ggaaggacgc
    23821 tggctgttgc agtaatcatt ccaaattgtt ccattaaata tcctcactta tagtcttgca
    23881 agaagtcgtg caagtttttc agtgcatcca gcaaggcatg ctgttcctcc gtagccattc
    23941 cgtctaagat gttcttgacc atttcacgat gaaaatgctg atggacccga aatagtaact
    24001 ttcctttttt cgttagtccc aactttacaa cgcggcggtc atcttcactg cggatacgtt
    24061 cgacatagcc tttttttact aacttgttaa tagcagtggt caaggtccca acagtaattg
    24121 atagttcttt ggctacttct gaagttgttt ttttcttgta catcccgatt gcctcgatcg
    24181 tgtgcatctc tgtgattgac agatctttga attgagattt tttcagctca gactcttcga
    24241 ttgtcaaaat atcattgaag acactaacaa gataatcatt tactgttttt aaatctggtt
    24301 ccatgttcca ccgtccacta attagtttga ttatcaaatc ttttgatgtt caaactatat
    24361 cttaactttt ttcaaaatgc aaccttaaaa gatcattttt ttactatatg agcttttttt
    24421 aagattttac tcatttaaaa caactgataa atcagcattt ataatttctt ttattagaaa
    24481 aatcatctat ctcacatatt ttgattatca aagtattttc tgtgaacaga actatagaat
    24541 tccctaaaac ttgtccatta tttcaaaatt tgttatagtc tttttattca aagcgtaaaa
    24601 ggagatccta tgttaaaaga aaaaatgaaa actctcccca tgctgccggg tgtctatctt
    24661 atgaaagacc gagatggtaa ggtcatctat gttggtaaag caaaacggct caaaaataga
    24721 gtaagcagct attttcatca gaataaacag cattcaaaaa aagtattacg tatgattcat
    24781 catataacag attttgattt cgtcgtagta gacacggaat tagatgcttt attgctcgag
    24841 tgtcaattga tccaacatta ccgtcctttt tataaccgac aaatgaatta tttcagtaat
    24901 tataattatg tacatattac caataaggga tttgtattaa cagatactcc tacggctcga
    24961 acatacgggc cttttcgtct ctataaaaaa atgccgtcta ttttgcgtat aatggaagaa
    25021 acttatcaaa tgccttggtt gtctgaaatt agtttgttag ctttgcgagt ccagcttcct
    25081 gacctacagg aaatgacttt tgaacagaaa aaaaaggaac tccaagggct gtttcaaggc
    25141 cgaaataaaa agctactgac ttacttgaaa aaaagacaac aacatttcat ctatcagttg
    25201 aatttcgaaa aagccggtat gcttcaaaaa gatatcgaat tagttactta ttttattaga
    25261 cggatccagg aacaaaagca gtttttaaga acaccatcgc tcaccttcag catgccatta
    25321 gcagcagatg agagtcagaa aaagcactac ctcgtttgtt atggtcaact tgcagaaaca
    25381 atgattacct ctggtgacgt ttctcctgac ttctattatg aaaagaaaga agctcattta
    25441 tctttgaaac gtcaattgtc aaaagaagaa atcgatcctg tacaaatctt gatcagttac
    25501 cgcaaaaaat tagaaaaaga acagtttgaa attgaactgt taaacaaaaa agaagctgaa
    25561 aagcaactaa attagttgct tctcggcttc ttttaggcat cttcaacttc aaatgtcaat
    25621 tatcctaaaa tttattggat taagtcatag atttccatcg ctacgatatc gatattatca
    25681 aattcgtatt gctgatgagt atctgtttca gttaattcaa atgtatcggt cgctttatca
    25741 taagttactg tacacttctc tacgccttct ttttcaaaac ggcgaacttg cagttcatta
    25801 tctgctgact cgaccatagc ctccagtcgt tttatgattg cgactaattg tgaatgtgtc
    25861 atcggaggtc ctccttttct tatttctgtt atattgtatc aaaagcatag cctacttgca
    25921 ttgattttct ctaaaaaaac tcgtttttta tgattttttt tctggtattt ttccttcagg
    25981 ccaccaaagt ttgatcaaag cttgggttcc gtcattctca aaacctttat ctgccaactc
    26041 ttcatatagt ttcaatgctt gggtagttgc tggcaataca agatccattt tttctgcttc
    26101 ttctaatgca atctttaaat ctttgataaa atgtttgaca aaaaaaccag gtgtgtaatc
    26161 ttcttttaaa atacgaggag aataattgct taaagaccag ttagctgcac ttccacctga
    26221 aagcgtctca atcactttct ttaaatcaag tccgtttttt tgtgcataga caagcatttc
    26281 cgtcattcct gtcatcgtac ctgcaatcat gatctgatta gccatttttg tatgctgacc
    26341 tttcccagca gaaccatgca atgtaaatgt cgtaccaaat tctttgaata aaggcagtac
    26401 ttgatcataa acggcttctt ctccaccgac catgatcgtc agtgtaccat tctttgctcc
    26461 taagtcacca ccggataccg gtgcatctaa cgcatctgcg cctttttctt ttgctgtttt
    26521 tgcaattttt tctgccaggc ttggtgtact tgtagtcaaa tcaactaaaa tatgtcctga
    26581 gatatctgca gaaaaaatcc ccgactgtcc atagtagatt tcttctacat ctttggggta
    26641 acctaccatt gtaaagagaa tattactttg ttctgctacc gcttttggtg tatctgccca
    26701 gatagctcct tctgttacta aaggatcagc ttttgctttt gtccgattat agacagctac
    26761 ttcgtgtcct gcttctagta gatggcgtgc gacagcactt cccatgacgc ctgttccgat
    26821 aaaaccaagt ttcatttttt cgacctccta aaaatcaaaa atccttgctt ctatgctagt
    26881 atacgctaga aacaaggatt ttttcataaa aaatgtttga attttatctt ttaaatgaat
    26941 ttaattttat tttgattcgt tcaatcgagt cttcttcttc ttttcttcgc atctcttctt
    27001 catgataaac aaccatgtct tgataaaatt cgatcatagc ttcgccgaaa tgtgtagatg
    27061 aaatatcata aagtttagct tctaaaactt ttggatcttt aggaacttca ctggaaatat
    27121 aatcaataag tgctggtgca aagtcttcgt cggtttcaaa agttttccct aatgaaggat
    27181 gatcgaacaa tcggttcaaa taagcatttc cttccacgac acaaggtgtt ccggctgcca
    27241 tcgcttctgt ataagtaagc ccttgtgttt ctgaagtaga agcactgaca aaataatctg
    27301 ccgctttata ataaagtgct acatcattgt tgtccacttc tcctgtgaac tgcacaaatt
    27361 cttctaactg cagttctgag atcaattcct ctaactcttc tacataaggt ccttttccta
    27421 cgataactaa tctggcgtta ggataagcgg agatgacctg aggaaaccca ttaatcaagg
    27481 cttggatatt tttctcataa gaaatcctgc ttaaagaaag aatcatcaaa tggttttcct
    27541 gaagacctag tgactccctt aatttgctga tatcctgctg agtgatatca gaacgtttga
    27601 atttttcaat gtcgatacca gtaggaatca cgcgaagcgg tgctattaca ccatagctgc
    27661 gtaatgtatc aataacacgt tcacttggac aaactacacc tgtcgtatga tttgcaaata
    27721 atctagacaa gtattttaca tgggattgcc tgatcacttt tcctttaccg atataatgaa
    27781 ggtagtcttc atacatcgta tggtaagtat ggatcagagg tattttcaac ttcttagcta
    27841 ccatcttccc aagtatccct gctccgaatt ctgtatgggt atgaataaga tctagttcta
    27901 gttctttggc aaccaaataa gcataccaca tgcctctaac aacaactctt cgatccttga
    27961 aagaaataaa tggtacactt ggcattcgaa tcacatcttt ttccaactta tccgcattag
    28021 gatcggtcgt tgtaaaaata tagacttcat gcccatgtct ttctaattct tgttttaatg
    28081 ttttgatcga tgtagcaact ccgctgactt gcggaaagta ggtatcggta aaaaagccga
    28141 ttttcatgtt tttcgcctcc aaactagtcc ttgacctgat ttactttttt taatttgcta
    28201 gagacttttt cattcagtac actttcgtat acatttttaa gttcttcacc gattttattg
    28261 atacttcgct cttttgctgt ttgataaccg gcttgtgtcg tactcggtag ttcttgattg
    28321 gtaatctgtt ggatcagtcg gataaattct tcgtttgtct tccccatata gcagttcttg
    28381 ctatcttcta accagccatt atacactgga atatctcgaa caagtacgtt ttgtttgctt
    28441 gctaaagctt ctaaaacaac gatcccttct gtctcttcat aagaagggaa aaagaataga
    28501 tctgcacctg aatacgcacc ttctatgatc tctccacgaa tgtaaccagg aaacaggaca
    28561 ttttcaggat gatcttcttt tacaattttc cggatgttcc gaggaatcga gtacatggga
    28621 acatgaccaa accaaataaa tgtgtattcg ggcatcttct tagcaatttc tacgaaatca
    28681 atgattcctt tacgttcgaa aaacaaaccg acacaaatga ttactttttg atccggagac
    28741 agtttgaaat attctctgaa cttttgttct ttcattggat cagggtgata tttctctaag
    28801 tcgatcccat tggaaatagc ttgaatcggc acacggatac catagctttc caacaactgt
    28861 tttgaataag gtgttggcgt gatcagatag tccgcttttt ggtacaatcc taccagatat
    28921 ttttttacga taggagaaag ctggttcgat ccgataaagg aatttcggaa atcttcctct
    28981 gtagaatgcg catgatagac aacttttttt ccttctcttc tggctttatt gaccatatta
    29041 tgactattga ttccgtatgt attgatgtgc aggatgtcat aatcttcttt ttcatctagt
    29101 gtataagaga taccgacttc cgtcagagca cgtttttgat gatcaagcgc acgcccgatt
    29161 ccagattttg caagcatctt ttcactttca aaatataata ataccttcac cttacgtccc
    29221 ccttcactta tatagtataa catagcctac aaactgtcac tcaaacttaa gccctatttt
    29281 tgtctattct tactgacaaa aacgttttct taaaaaagaa caaaaaaact ggcgtagctc
    29341 ttttacaagc cacaccagct tttgatacgt tgtttatttt acatattcat gaacaagttc
    29401 aacgacttct tccatcatat cgcattcttt caatgcacga tcagcaagtt cagccatttt
    29461 cgctgtgtcc aagcgtttca ttaaactacg cgttttaaga atagatgtcg cactcattga
    29521 gaactcatct agacccatac ctactagcaa tggaacagct gtttgatctc cagccatttc
    29581 tccacacata cctgcccatt ttccttcagc gtgtgctgca tcaattacat ttttgatcaa
    29641 acgtaaaatt gatgggttat atggttggta caagtaagaa acgcgttcgt tcatacggtc
    29701 tgctgccatt gtgtattgaa tcaaatcgtt cgtacctaca gagaagaaat ctacttcttt
    29761 tgcaaacttg tctgctaaga ctgctgctgc tggaatctcg atcatgatgc cgacttggat
    29821 cgtatcagat acttccttgc cttcacttat caatttttgt ttttcttctt caaagatcgc
    29881 ttttgctgcg cggaattctt tgagtgtagc taccataggg aacatgatac gtaaattacc
    29941 atgaacagat gcacgaagca atgcacgcat ttgtgtacgg aacatttcgt cgccttgttc
    30001 agataaactg atacgcaatg cacgatatcc taagaatgga ttcatttcat gaggtaattg
    30061 cagatatggt agttctttat ctccaccgat gtccattgta cgaacaacta caggttttcc
    30121 ttccatacct tctaatacag ctttgtaagc ttcatattgg tcatcttctg ttgggaagtc
    30181 tggagaatcc atatacagga attcagtacg gtacagacca actgcttctc caccattatt
    30241 atggacacca actagatctt ttggtgttcc gatgtttgca gctaattcaa aatgcttgcc
    30301 gtcagctgtg acagtttctg cattttttaa tttttcccat tctgcttttt gtgctgcgta
    30361 atctgcacct gctttttcaa attcagcttt ttgttcatct gtaggatcga tgattacatc
    30421 gccttcgatc ccgttgacag ccaaaatatc gccttctttg actttagcag taatttcttt
    30481 tgtcccaacg attgctggaa tttctaaaga acgtgccatg atagcagaat gtgaagtacg
    30541 tccaccaatg tctgttacaa acgcttttac aaaattgcga tctaattgtg ctgtatcact
    30601 tggagtcaag tcatgtgcaa caacgaccac ttcttcgttg atcattgatg gatttggtaa
    30661 agtaacgcct aataagtgcg ctaaaatacg tttagcaacg tcacgaatat ctgcagcacg
    30721 ctcttgcata taagcattat cttccattgc ttcgaacata ccgatataca tatccgttac
    30781 ttcttttagc gctgattcag catttacgct gttgtcttta atattttgct tgatttgacc
    30841 taccatttct ggatctgaaa gaaccatcaa atgggcatca aatacttgcg cttctgcttc
    30901 acctaagctt tgcgctgctt tttcacgaat ttgctgcaat tcttcagtag atttagctaa
    30961 tgcagcatcc aaacgagctt cttcagccgc agtatcttct actgttgcct tactgaatgt
    31021 taaatccggt tgaactagca ggtaagcttt tgcaacggct acaccgtcac tagcggcaat
    31081 cccttttagc atttcaacca ttattcagat aagccttctt tcttcattgt ttcaacgatt
    31141 gctgccattg catcagcttc gtcagcacct tctgcagtaa tagtaacatc agaaccttga
    31201 cctacaccta aagacataac gcccatgatt gatttcaagt ttactgattt acctttatac
    31261 tctaagttta catcagagtt aaatttgctt gctgtttgta ctaatagtgt agctggacga
    31321 gcgtggatcc cagtttctgc tactacgtga aattctttct tttccatatt aatcggtctc
    31381 ctttaagtga gtgttgtttt tatgtgaggg ttttcttttt tagtaattca gagaatccta
    31441 acaaatgcca ccctttcatc tgtaaagatt aacatttttt ttcgttagat acaacagttt
    31501 tcattcaatt tcagataaaa gtattcaaat tattccggat tctttttcat ccttttcttc
    31561 acattttata acaaacgtgt ttatttcctt tttcttgtcg ctttctcttc tcctgacgtt
    31621 tatcattctt tcctttgacc ctctttgttt tcatatgaaa cgaattactt gcttcccttt
    31681 ttatttttag tataataaga gtcaaaggtc aggaatggtc aatagagatt tcaccttttc
    31741 tacctcataa atctcttaaa aaactagggg ttattctttt acctcatgaa aaacgagatg
    31801 taaaatatgg atgtacccat ttttgtgaaa ggacgtgaat gattcatgct ttgtcaaaac
    31861 tgcggcaaga atgaggcaac gattcacttg tatgccactg tcaatggtca gcggacacaa
    31921 ctcgattact gtcagagctg ttatcaaaaa atcaaaaatc aacaaaatgg aggtctgact
    31981 aatatggccc aaaatgatcc atttggattt ggcagtttgg acgatctttt ccgttccatg
    32041 tctcgccaaa tgcaacagca aggaaattat gagcaaacac caccaacaca atttggcgga
    32101 aacaacaact tcaatggtgg tcagccacct caaggcaata cagaaggttt attgggagaa
    32161 tacggaatca atatcacaga acaagcacga caaggtgata tcgatcctgt gatcggacgc
    32221 gatgacgaaa tcaaacgagt cattgaaatt ttaaatcgcc gaaccaagaa caatcctgtc
    32281 ttgattggag aaccaggtgt tggtaaaaca gcagttgttg aaggtttagc acaaaaaatc
    32341 gtagatggtg atgtaccgca aaaattaatg gacaaagaag tcattcgttt agatgtcgta
    32401 tctttagtcc aaggtactgg tatacgagga caatttgaag aacgtatgca aaaattgatt
    32461 gaagagatcc gtcaagcaga aaatgtgatc ctattcatag atgaagttca cgaaatcgtc
    32521 ggtgctggtt ctgctggtga tggaaatatg gatgctggta atattttaaa accagcttta
    32581 gctcgaggag aattgcaaat ggttggtgct actaccttaa atgagtaccg catcatcgaa
    32641 aaagacgctg ctttagaacg tcgtatgcaa cctgtacggg tagatgaacc aactgtcgaa
    32701 gaaacgatca gtattttgaa aggtttgcaa aaacgttatg aagactatca tcatgtaaaa
    32761 tatactgatg aggccatcga agcagccgca actttatcca atcgttacgt ccaagatcgc
    32821 ttcttgccgg ataaagccat cgatttgcta gatgaaacag gttctaagaa aaacttgacg
    32881 atccaaatcg ttgatcctaa aacaatcgag aaaaaactgc aagaagcaga agaacaaaaa
    32941 gttttagctt ctcgagaaga agatttcgaa aaagcagctt attatcgcga tcagatcaat
    33001 aaacttcaaa aaatgaaaga acgtcagctc actgaagagg aaacacctgt gattaccgaa
    33061 aaagatatgg aaaaaatcgt tgaacaacgg acaggtattc cagtgggtga attaaaagaa
    33121 aaagaacaga cacaactgaa aaacttagca gatgacttga aagctcatgt catcggacaa
    33181 gataacgctg tagatcgagt agcgaaagcg attcgccgaa accgtgttgg attaaacaaa
    33241 cagaatcgtc caatcggctc cttcttattt gttggaccaa ctggtgtagg taaaacagag
    33301 cttgcgaaac aacttgccta cgaactattc ggttcacaag attcaatgat tcgtttcgat
    33361 atgtctgaat atatggaaaa acatagtgtc tctaaattga ttggttctcc tccaggttat
    33421 gtcggatacg aagaagctgg tcaattaaca gaaaaagtac ggagaaatcc ttacagtctt
    33481 gtcttgttag atgaagtaga aaaagctcat ccagatgttt tgcatatgtt cttgcaaatc
    33541 ttagatgatg gtcgattgac agatgcacaa ggaagaacgg tcagctttaa agatacgatc
    33601 atcattatga caagtaatgc cggaactggt aaagtagaag caaacgttgg ttttggtgcg
    33661 gcacgcgaag gtgttactcg ttctgtattg aaccaattaa acaactactt tacaccagaa
    33721 tttctgaacc gttttgacgg gatcatcgaa ttcagtgcat tatcaaaaga aaacttgatg
    33781 acaatcgtca cactaatgct agacgatgtc aaccaaatgc tggcagcaca gcaacttcac
    33841 atcgaagttc ctacgaatgt caaagaaaaa ttagttgact taggctatga tccatctatg
    33901 ggtgctcgtc ctcttcgacg cacgatccaa gaacaaatcg aagatggtat cgctgaattt
    33961 tatcttgatc acccttctat ccatgagttg aaagcaaaac tggataaaga tggaaaaatc
    34021 atcgttactt ctaaaccaga acgtttggct aaagaatcag ccgaagaaac ggctgaataa
    34081 atccagtttt atagcgtgag acggtatttc tttgagaaat gccgtctcat tcttttttca
    34141 gaaaagtcaa aatactgttc attttataaa aaagaaatta taataagaga aacaagcaat
    34201 taaaaataca taaaagaggt gagcgccatg aaattggtaa atgtaacaaa cagccattcc
    34261 cgtcttgtat taaaccagct tgaaaacact gatgcccatc tagtcaaggt ctacacagcc
    34321 ggaaatacca ctattgtcta cactgaagcc cctgaacata atgaaattct gctgatcaat
    34381 gacaaacgta aaatccagcc gaaagaaatc gaagatgcta aaaattattt cttagataaa
    34441 atcaaagacg ccgtttacca cgaggatgaa atcaaagtaa tcgaattggc aggccttgtt
    34501 gaaatctcga ttccaaaaca tgaattaggc gctacattag ccgtgtaaac aaattttgaa
    34561 cataataatt aaagagcgtg ggacaaaagt aaagaacact tttgtctcac gctctaaaca
    34621 cgtataaacg gcgaaagcag aagcaactcc ttcggaaata agctgaaatt cacgaaaatt
    34681 gcttttcaaa tttttgtgaa ttccagctta tttcttggag ttaaacgctt ctgtctcagc
    34741 ctctttttct ttctagcttt ttgatttttc tcttttcttt tgtacttttc tcttttcatt
    34801 ttcagttcta cgcgtgtctt tatttttaac tttttcctct ttatggatga ttgatcgtac
    34861 tttttgtgca atttgctcgt ttttgtccca gtcttttaca tctaataatc gacataatcg
    34921 taacatctct tcttttttct gtttttttct ttcacgtctt tgccattctg tttccatgtg
    34981 tcacactctc ctttctttaa tcatatgtac gcaaaataat ttttatattt ttttgattag
    35041 ac
//
LOCUS       DAXLPC010000021        34714 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.021, whole genome shotgun sequence.
ACCESSION   DAXLPC010000021 DAXLPC010000000
VERSION     DAXLPC010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.021"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(129..587)
                     /locus_tag="ACF3UE_000984"
     CDS             complement(129..587)
                     /locus_tag="ACF3UE_000984"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFD3634437.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(758..1903)
                     /locus_tag="ACF3UE_000985"
     CDS             complement(758..1903)
                     /locus_tag="ACF3UE_000985"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFD3634438.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPHHELHGVAKQQMSGFSGMISFTLKNEETAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(1916..2833)
                     /locus_tag="ACF3UE_000986"
     CDS             complement(1916..2833)
                     /locus_tag="ACF3UE_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFD3634439.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3261..3824
                     /gene="efp"
                     /locus_tag="ACF3UE_000987"
     CDS             3261..3824
                     /gene="efp"
                     /locus_tag="ACF3UE_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFD3634440.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            3925..4095
                     /locus_tag="ACF3UE_000988"
     CDS             3925..4095
                     /locus_tag="ACF3UE_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634441.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEREETALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            4310..5569
                     /gene="lysA"
                     /locus_tag="ACF3UE_000989"
     CDS             4310..5569
                     /gene="lysA"
                     /locus_tag="ACF3UE_000989"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFD3634442.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKERSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            5556..6356
                     /gene="dapF"
                     /locus_tag="ACF3UE_000990"
     CDS             5556..6356
                     /gene="dapF"
                     /locus_tag="ACF3UE_000990"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFD3634443.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDTDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6359..7240
                     /gene="dapA"
                     /locus_tag="ACF3UE_000991"
     CDS             6359..7240
                     /gene="dapA"
                     /locus_tag="ACF3UE_000991"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFD3634444.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7237..7953
                     /gene="dapB"
                     /locus_tag="ACF3UE_000992"
     CDS             7237..7953
                     /gene="dapB"
                     /locus_tag="ACF3UE_000992"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFD3634445.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            7959..8654
                     /gene="dapD"
                     /locus_tag="ACF3UE_000993"
     CDS             7959..8654
                     /gene="dapD"
                     /locus_tag="ACF3UE_000993"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFD3634446.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAGTVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            8670..9671
                     /locus_tag="ACF3UE_000994"
     CDS             8670..9671
                     /locus_tag="ACF3UE_000994"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFD3634447.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            9668..11029
                     /locus_tag="ACF3UE_000995"
     CDS             9668..11029
                     /locus_tag="ACF3UE_000995"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFD3634448.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYSKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            10989..12140
                     /locus_tag="ACF3UE_000996"
     CDS             10989..12140
                     /locus_tag="ACF3UE_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFD3634449.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSGAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFHYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSRSKEERVYNDEFIQSI"
     gene            12115..13284
                     /locus_tag="ACF3UE_000997"
     CDS             12115..13284
                     /locus_tag="ACF3UE_000997"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFD3634450.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPKHVKQAGIAAIEEDFSHYTGMRGLEELREAACMFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            13460..14839
                     /locus_tag="ACF3UE_000998"
     CDS             13460..14839
                     /locus_tag="ACF3UE_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3634451.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSVSDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15120..15917
                     /locus_tag="ACF3UE_000999"
                     /pseudo
     CDS             15120..15917
                     /locus_tag="ACF3UE_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            16106..16774
                     /locus_tag="ACF3UE_001000"
     CDS             16106..16774
                     /locus_tag="ACF3UE_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFD3634452.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(16974..17360)
                     /locus_tag="ACF3UE_001001"
     CDS             complement(16974..17360)
                     /locus_tag="ACF3UE_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634453.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(17332..18630)
                     /locus_tag="ACF3UE_001002"
                     /pseudo
     CDS             complement(17332..18630)
                     /locus_tag="ACF3UE_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
     gene            complement(18744..20606)
                     /gene="ltrA"
                     /locus_tag="ACF3UE_001003"
     CDS             complement(18744..20606)
                     /gene="ltrA"
                     /locus_tag="ACF3UE_001003"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFD3634454.1"
                     /translation="MENVSASHSIRHMEYYGLIDSFDSLYKESSENKIFSNLMEIVTS
                     PNNILLAFRNVKGNSGSTSPGVDKKNIDDLKAIPNIEFIKTVQTKFSEYKPQPVKRVD
                     IPKPNGKTRPLGIPTIWDRIIQQCLLQVLEPIMEAKFHDKNYGFRPNRSAHHAFAQAV
                     RMAQLSKLTFVVDIDIEGFFDNVNHSKLIKQFWTLGVRDKWLLGVIRAMLKAPIIHRD
                     GRIEHPKKGTPQGGVLSPLLANVVLNELDWWISSQWETHPTRKNYDCYHQTRKQWIKS
                     NKYRALRASKLKEIYIVRYADDFKIFCRKRSDADKIFLATKLWLKDRLKLDISAEKSK
                     VVNLKKQKSDFLGFTMKLVRKRKSFVIETHMCAKAMSAASNKLAKQIKVIQHSPTQVE
                     LQKQLSIYNSMVVGIHQYYKKATHISVDCPRINQRLMIIIKNRLDIKRKGPPPSDFIK
                     KNYARSKQLRWLNGVPMLPFGFIKHSHTSLPKIGTCKYTPEGRVLIHRYLTFPIDIIN
                     QLMNMSNPNESIEFRDNRVSKYSSQVGRCRVTKEVLELADIYCHRIVPKNLGGKDNYQ
                     NLVIVHRNIHSLIHEEDKTRASLLIQNMRVTSAQLEIINQFRKKAKNRELSLNL"
     gene            complement(21556..22743)
                     /locus_tag="ACF3UE_001004"
     CDS             complement(21556..22743)
                     /locus_tag="ACF3UE_001004"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFD3634455.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(22750..23781)
                     /locus_tag="ACF3UE_001005"
     CDS             complement(22750..23781)
                     /locus_tag="ACF3UE_001005"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFD3634456.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(23797..25251)
                     /locus_tag="ACF3UE_001006"
     CDS             complement(23797..25251)
                     /locus_tag="ACF3UE_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFD3634457.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            25426..26331
                     /locus_tag="ACF3UE_001007"
     CDS             25426..26331
                     /locus_tag="ACF3UE_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFD3634458.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            26422..27099
                     /locus_tag="ACF3UE_001008"
     CDS             26422..27099
                     /locus_tag="ACF3UE_001008"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFD3634459.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            27096..27266
                     /locus_tag="ACF3UE_001009"
     CDS             27096..27266
                     /locus_tag="ACF3UE_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634460.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            27380..28276
                     /locus_tag="ACF3UE_001010"
     CDS             27380..28276
                     /locus_tag="ACF3UE_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3634461.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(28331..29701)
                     /locus_tag="ACF3UE_001011"
     CDS             complement(28331..29701)
                     /locus_tag="ACF3UE_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3634462.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            29939..30685
                     /locus_tag="ACF3UE_001012"
     CDS             29939..30685
                     /locus_tag="ACF3UE_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFD3634463.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQPVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            30682..31521
                     /locus_tag="ACF3UE_001013"
     CDS             30682..31521
                     /locus_tag="ACF3UE_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFD3634464.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            31522..32472
                     /locus_tag="ACF3UE_001014"
     CDS             31522..32472
                     /locus_tag="ACF3UE_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFD3634465.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            32613..33365
                     /locus_tag="ACF3UE_001015"
     CDS             32613..33365
                     /locus_tag="ACF3UE_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634466.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            33384..34535
                     /gene="queG"
                     /locus_tag="ACF3UE_001016"
     CDS             33384..34535
                     /gene="queG"
                     /locus_tag="ACF3UE_001016"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFD3634467.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT        11162 a         6386 c         7123 g        10043 t
ORIGIN      
        1 aaaagagcgc taaactgaaa actagctatt tgttttcccg tttagaactc ttttcagaca
       61 ataaatattt aataaaatac gaagataaga tagctatatt gcttctcatc tttacgttct
      121 tttagaaact atgcttctac ttcagaccat tcatcgcgtt ttgctaaaaa ttcacgagcc
      181 aaagcttgtg caccttctag tgtatggctg gcagcccagc cacattgtgt ttcattgctt
      241 gcaggtactt cagtagcttc aagaacatct ttcattgttg cttcaagaac atctaaaatg
      301 tcttcgtagc tttcatgatt caatacagtc aagtaaaagc ctgtttggca tcccattgga
      361 gaccagtcta cgatgtaatc tgcgtgattg cggattagtt cggcagtcaa gtgctcaagt
      421 gaatgtagac ttggcatgtc catgtgttct ttatttggtt gtttaaagcg gacgtcgtat
      481 ttaatgatga catcgccatg cgcacccgtt tttcgatcag ctacacgtac ataaggtgct
      541 ttgacttttg tatggtcaag attaaaactt tcgacattca ttctcatttg taagactcct
      601 atctgtttgt tcattcgttt tgatgctttt cactaaagaa ttatttagtg aaatttacaa
      661 aaacgtcttt ctacttgatt ctaacactta tcgtttccaa ggtgtagcaa tctgaaatat
      721 tttttagatt tttctgctaa gtcgtttatt gggacttcta gttcttgatt ctgtcaaatg
      781 cctgagctaa atcgtttatg agatcctgac catactcaat tcctacagaa agacggatca
      841 agccgtcctt tatgccagcc tcttctcgtt tttcttttgg aatagacgca tgagtcatga
      901 cagaaggaat ttccactaaa ctttctacgc cacctaaact ttctgctaaa gtaaatagtt
      961 ggagtgattc aacaaatgga atagcagttt cttcattttt taaagtaaaa gaaatcattc
     1021 cgctaaagcc gctcatctgc tgcttagcaa ctccatggag ttcatgatgg ggtaatcctg
     1081 gatagtagac cttttctact gctggatgag aaaatagaaa atcagctacc acaaaagcat
     1141 ttttttgatg ttcctccata cgaacactta gtgtcttgat tccgcgctga agtaaccaac
     1201 tatcttgggg accaagtacg gctccgatag cattttggta aaatccgatc tgatcggcta
     1261 gatctttatg gttagaagtc actaaaccag ctactacatc gctgtgtccg cctagatatt
     1321 tggtaccgct atggacaacg atatcagaac cgagatctaa aggtctttga aaataaggag
     1381 tagcaaatgt attgtcagca ataactatca atccatgttg atgagccaga gtggcacttt
     1441 tttctaaatc agtaatcttt agaagcggat tgctaggtgt ttcaagataa agtgcttttg
     1501 tattgggttt gatggattgt tctattttat caagattact cgtatctatg atcgtgtact
     1561 cgagaccatt tttagtaaga actttgtcaa atagacggaa tgttcctcca tagacatcat
     1621 ctcctaataa gatatgatcg ccagcttgaa aaagagaaaa aacggcatga atcccagaaa
     1681 gaccagaaga aaaagcgaat cctcgaacac cgccttccaa atcagcaatc agttcttcca
     1741 atgcaaaacg agtaggatta ccagatctcg aatattcata ttgcttaggc tggccgacgc
     1801 catcttgccg ataagtggat gtttgataaa taggtacact gacagctcct gttgtgggat
     1861 cttcactgat gcctccgtgg atcaattttg tttgaatgtg catgtttctt tcctcctata
     1921 agtaaatgtt ttttgataaa tagcggtctg ctgcgtctgg aaaaatcgta acgacacgat
     1981 gaccaggtgg taaacgacga atttctctta atgctgctgc aaaagccgca ccactcgaac
     2041 ttccaactaa tagtccttgt tctcgtgcta actgcctagt atagttaaac ccttctacat
     2101 cagagattgt ctcgatctga ttgattgaaa ggggagaaag aaacggcgga atgaattcta
     2161 caccgatacc ctcaatttcg tgaggggctg gatcaccacc atttaacaca gagccctctg
     2221 gttctacacc gattattcga atgtcgggat atttttcttt caaaaaggta gaagttccag
     2281 caaaggttcc accactccca attcctgcta caaaactatg gatattttct ttgatttcat
     2341 gaaagatttc tggccctaac gtatgatagt aagcagcagg attatcttta ttttcaaatt
     2401 gaagaggcag atagctgttt gatatctcct ctgcaagttt tttacttttg ctgatggcac
     2461 cgatgattcc ttgctcacta ggagaatgga tgatctttgc tcccaatgct ttcatcaatt
     2521 gttgtttttc taagctaaac ttctctggaa caacaaaaac cgttcttaat ttgtatgtga
     2581 gtgcggccag agcgatccca attcctgtat ttccggcagt tggttcgatg atcgtcgttt
     2641 tttcattgat ttttccttgg gcaaatcctt ctttgatcaa ataactgccc aatctatctt
     2701 tgatacttcc tccaggattt aaatattcta gttttgcata aatagcagaa cctttaggca
     2761 tagaatagtg ctgattgtca aagcgataaa gcggtgtgga accaatagct tctgtaattg
     2821 tcgagataat catatgggcc tcctaaaaaa agataataaa aaaaggagct gactattaaa
     2881 tcagctcctt gaaagacata gagaaaaatt gagtagataa aaagataagt tacctggtac
     2941 tcattctatg aagggcaatt aatagacatg acaaatagta tgctgctttt atgcaccata
     3001 caacagcaac gattcaattg tttttggttg ctgactgtca tgtgtatccc tccaagtaaa
     3061 atttttatta acgatagcat gaaaaaaaat aaaagtcaaa ggattgaaag aaaaaaatat
     3121 ttcgatagca tcgtttaccc gtgtttattt ttctgacaaa taggcatgag accttaaaag
     3181 atagagaata ctctagtttt ctggccggtt gtctgataca ataaagttga ttatgataaa
     3241 gaaaagaagg agcaaaaata atgatctcag caagtgattt aagagccggt atgactttcg
     3301 tacaagacgg caaactgatt aaagttctgg atgcaagcca ccataaacct ggtaaaggaa
     3361 atacagttat gcgtatgaaa ctgaaagatg tccgttcagg tgcaacatac gacacaacgt
     3421 tcagaccaga agaaaaattt gaaaaagcac acatcgacac aaaacctgta caatatttgt
     3481 acacgatgga tgatacagct ttcttcatgg atttggaaac atatgagcaa tatgaaattc
     3541 ctgtagaaac agtagaagaa gaaatgaaat atatcctaga aaacatggaa gtaaaaatcc
     3601 aattcttcgg tagcgaagtc atcggcgttc aattaccaac aactgtcgta ttacgtgttg
     3661 tggaaacaca accttccatc aaaggtgcaa cagtcactgg ttcaggtaaa ccagcgacaa
     3721 tggaaactgg cttagtagtc aatgttcctg acttcatcga aacagatgaa ttgttggaaa
     3781 tcaatacagc agaaggttct tatgtaaaac gtgcgtcaaa ataattcgct aacggattga
     3841 taagaatttg aaaacagagc ttgacctctt gaaaggcaga tcatcggatc tgcctttcaa
     3901 gaggtttttt gtggaatcag caaattgaaa aataaaaaag tatttgattt tatttatatt
     3961 ttgaaagatg aatggcaaaa gctagagaga gaagaaactg cacttattta tgaagaaatt
     4021 gaaatgattc ataaaattga aaatatccga actattccga actatattga agcgaaaata
     4081 ttttttcatc actaaatagt gttgaattta tgtttttgtg tataaatagc ttctaatagt
     4141 tcgggtattt tgtttttata accattttta ttcttatttt taaaaaaata tttcgaaata
     4201 tactagacaa ttcagaaaat tttgtttaat attattccaa taaaattcaa atctttatca
     4261 aatgaaattc caataaaaac ggaaaaaaag tgaaaagagg aatgaaaaaa tgacagaatt
     4321 gataattggc ggagtcacag caagcacatt ggcagaaaag tataagacac ctctgtatgt
     4381 gtatgatgaa gaaaagatga gacaaacgat gctgtcattc aagcgaggct ttgtatcgaa
     4441 acgttttgat acaaaagtac tttacgcctc taaagcattc caaacgattg agatgctgca
     4501 tttagttcgt gaatatggat tcgggctaga tgttgtcagt ggtggggaaa tctataccgc
     4561 tttgcaagct gatttcccta gagatactat ctacttccat ggtaacaaca agacgccaga
     4621 ggaactgatc tatgcacttg aaaatgattt gttgcatatt gttgccgata atttgatgga
     4681 agttgaatta ttagcagaat taagccaacg ctatttaaaa aaaatctgta tcatgcttcg
     4741 gttgaatgtc ggagtagaag cacatactca tgaatatatc gtcactgcgc atattgattc
     4801 aaaattcggc atgagctatg aaagtaaaga gtgccaacaa gcccttcagt tgataaaaga
     4861 aagaagctat ctagagttag aaggatttca tgctcatatc gggtcacaaa tttttgatgt
     4921 tactgcttgg ttagctgaaa tcgacaaatt gacgaattac ttaaccgatt ttgaccaacc
     4981 tctttccttg aatcttggcg gagggtttgg gattcgttat acacaaaatg atcagccaat
     5041 cccagtcgaa gaggcactaa aaaaactgat tgaatatacg gaagaagctt tggaaaaacg
     5101 aaaactgacc attcgtcaat tactgattga accgggtaga agtattgttg gagaagctgg
     5161 tacaacacta tacacgattg gtttcatcaa aaagacacca cataaaaaat attactttgt
     5221 agatggcggg atgacagata atatccgtcc agctctgtat caggcagaat acgattgtga
     5281 tttagcagca aaactgtcgg aagaaaaaac agagaaagtg acgattgcag gaaaaatgtg
     5341 tgaatcaggc gatgtggtaa ttaaagaagc ttatttgccg aaagcagaat cgggtgatct
     5401 tttagctgtt tattccacgg gagcttatgg atactcgatg agcagcaact acaatcgagc
     5461 gacacgacca gcagttgttt ttgtcaataa tggccaatca agactgattg ttcgcagaca
     5521 agcattttct gatctactaa ggggggaagt ttcctatgat ccttcataaa tataatggct
     5581 gcggaaatga ttttatctta ttagattacg cagaagacac agattatagt caattagccg
     5641 cttctttatg cacaaaagaa aaatatgata cagacggatt gatcgccgta aaaatcgatc
     5701 cgttggaaat gatctattac aacaaagatg gcagccgcgc gccgatgtgc ggaaatggca
     5761 ttcgctgttt tgctcgatac gtaaatgatc agaacatgat gaatgaacag gaattcaacg
     5821 tagagacatt agcaggcaca agaaaaatta cggtgttgga tccctcacct ttttattgca
     5881 gcgtagatat gggagtgcca gatgattctc cggaaaaaat caaagctaat caaacttatc
     5941 caataaaaaa ccaggaaata gagatcaatg gtgaaaaagt aacgatcact agtttatttt
     6001 taggaacgat tcataccgtt gtttttgttg aaaatgcgcg tgaggaagtc tggagaaaaa
     6061 gaggtgaact gatctgtcat catcctttgt tcaaagaaaa aaccaatgtc aactttgtag
     6121 aagtagtcaa tgaacaagaa ttgatcgtcc gtacctatga aagaggagta ggttggacac
     6181 ttgcttgcgg tacaggttgc tgtgcctctt atgtggttgc taaggaaact gggaaaattt
     6241 cagcagatca ggtagttgtt cacttggaac aaggagactt gatgatctct ggtgaggatg
     6301 cgatacaaat ggctggccca gcagttcatg aatggacaag aatattggag gaatgaagat
     6361 gataaaaggt tcgatcgtgg cgctgatcac gccgatgaat gaagagggat cagtagatta
     6421 tgctggtttg gaaaaattga tccaattcca tttagatgaa caaacagacg gattattagt
     6481 tttaggtaca acaggagaat cttctacgct cacacaatct gaggaggagc agatccttca
     6541 actgacagta aagaaagtgg ctggccgtgt gccggtgatt gcaggagctg gaacgaataa
     6601 tacgaaagaa acgattgaaa aagcgaagca ttttgcttct ttgggggcag acgcactttt
     6661 ggtcatcacc ccttactaca acaaaacaag tgatgcagga ctagctgctc attttacagc
     6721 aattgcagaa gcctcaccga ttccgcttat tttgtataat gttccttcta gaacaggcat
     6781 gtcgattcca atccatgtat tagtaaattt agcagaacat cctaatatca ttggtttgaa
     6841 agaagcctca ggagatatgg cttatgtgat ggatgccgct cggttgattg gagaagaatt
     6901 cttcctttac agtggaaatg atgatttgat cctaccagta atgagtgtag gaggaagcgg
     6961 tgtaataagt gtatgggcga atatccaacc taaaatagtc catgaattag taaaagatac
     7021 gcaggacgga agatggcagc aagcaaaaga aaagcaatta aatgcacttg aactgatcca
     7081 tgccttgttc agtgagacca atcctattcc tgtcaaagca gccatgtcat tattagactt
     7141 accttccgga cctctacgcc tgcctttagt ttctctttca aaagagaaaa agaaacaatt
     7201 agctcagctt ttgttaaaag aaaggacggt tgaaaaatga aaatcggact gattggcagt
     7261 ggacagatgg gaaatagagt cgaagaagtt gcacaagaaa gaggagatac ggtccttctt
     7321 ttacggacgg cacctaaaga agcaactacg cttgctttta cggaactgcc agaactgctt
     7381 attgattttt ctcatccaga taatttagag aaaatccttt cgtatagctt gtcttatcaa
     7441 cttccgttag tcattggcac gacaggttat acacaatcac agttccaaga aataaaagaa
     7501 catgccaaac atgtacctgt gatgtatagt gctaattttt cgttcggcat catggtgatg
     7561 aatcaactaa tcaagcaagc agctgcaatg ttgcaaggct ggcagatcga actgattgaa
     7621 aaacatcata gtcgtaaaaa agatgcacca tctggtactg caaatatgct gcttcaaaca
     7681 atccaagaag tgcaaaagct gcagcccgta tacaactggc aagggaaaaa aagagaagaa
     7741 aaccaaattg gtgtacacag tattcgtgca ggttctttac ctggtgaaca tgatgtattg
     7801 tttgctgcta ctgatgaaat atttacgatc aaacatgaat ctttttctaa tcgaatcttt
     7861 gctgcaggcg cagtagaagc agcggactgg ttgaaagatc agtcaccagg ttattacaaa
     7921 ttagaagatt tattaatgga caaaggggtg taaaaaacgt ggaagctcaa gaaatcatcc
     7981 gctacattca aacggcatct aaaaagacgc ctgtgaaagt ctatctgaat gtaaccgagc
     8041 caatcgaatt taaagaaagt aaagtttttg gtgaaggaag cagcttcgtt gtttttggtg
     8101 actatgagac gattgctccg gttttagaag ctgaatcaga aaaaatcatt gaaatcgaaa
     8161 tcgaaactgc tgcaagatac agcgcagttc ctttgctaga tattaaaaaa attaatgctc
     8221 gtatcgaacc aggtgctatt atcagagatc aagtgtcaat cggcaacaat gccgtgatca
     8281 tgatgggagc gattatcaat attggtgcag taatcggtga aaacacgatg attgatatgg
     8341 gtgctgtctt aggtggacga gcgacagtgg gcaaaaactg ccatattggt gcaggagctg
     8401 tcttagcagg tgtgatcgaa ccagcatcgg ccaaaccggt tatcgtagaa gacggcgtac
     8461 tggtaggtgc gaatgcagtg attgttgaag gtgtccatat tggaaaagat gcagtcgtgg
     8521 cagcaggagc agtggtttta gaagatgtgg cagcaggaac tgttgtcggt ggaatacctg
     8581 cacgtgtatt aaaaataagt gatgatcaga caaaagaaaa tacagcattg attgctgcgt
     8641 tacgcgaatt atagaggaga tggagaaaaa tgcgcgaaat agatacctgt attgtggggg
     8701 caaccggatt agtcggccaa acgatgctca aagtgttaga agaatatgat tttccagtag
     8761 gacgattgaa attattagct tcaaaacgtt cagccggtaa agtttgtgta ttcaagaaaa
     8821 agaaacacac tgtacaggaa ttgacagaaa cttcatttga aggatatgat ttagcgctat
     8881 tttctgcagg tgcttctgta tccaaagagt ttgcgccaat cgcacgaagt cagggactat
     8941 ttgtcataga taattcctca gcatggcggg aagattcgga tattccatta atcgttccag
     9001 aggtcaatct ggaagactat acattgaatc ggctgattgc aaatccaaat tgttcaacca
     9061 ttcaagcggt acttccgctt aaagctttac aagaagcctt tggtatccag cgagtcaatt
     9121 attcgaccta tcaagcagtt tctggttccg ggcaaaaagg cattgaagat cttcatcgta
     9181 cgcaaaatga cgaggaacca gttttgtatc cttataatat tagccaaacg gtgattccgg
     9241 aaatcgatca gcctttggaa aatgggtata caaaagaaga acagaaaatg ataaatgaga
     9301 cccgtaagat tctgcatcag cctgctttgc cagtatcagc aacctgcgta cgtgtgccaa
     9361 tcgaaaatgg acatggagtc tctgtggcag ttcaactgca aaaagagttt acgacggaag
     9421 aaattagaga gtgtctcagc cagtttccag ggattcaatt agaagatgat ctagcagcac
     9481 ataaatatcc gacgagcatt cttgctagag gaacagatat ggtttatgtt gggaggatca
     9541 gaaaagacac ttctttagag aacggattgt tgttctatac gactgccgat aacatacgca
     9601 aaggagccgc tgcgaatgcc gtacagattg ctgcagcttt aatgcagaaa atagcggagg
     9661 tggcaagatg agtaatacgc tgaaagtagc gaaattcggc ggaacatcga tgtctcatga
     9721 agagcaattc aaaaaagtcc gtacaattgt tctttcagat cccaatcgcc aagtgatcgt
     9781 tgtttctgct ttaggcaaac gtacgtcaga tgatgacaaa gtaacagact tactttattt
     9841 gatttatgct taccttcagc atcatgttga ttggacaccc ctttggaaaa ggatttgtga
     9901 tcgtttcatt caagtaagag atgttcttgc cctgcagtta cctattgaag atgaactagc
     9961 acgcatacag aaacaactgg aagacgaaaa gataactgaa gattatttag taagtagagg
    10021 tgaatatctg actgctcaac tgatggctga gtatcttggt taccagttta ttgacgcaaa
    10081 agacctgatt ttctttgact atgatgggaa aatcgatcag gaaaaaacag cacaggaaat
    10141 cacaaaagca tttaaaagat attcgaaaat ggttgttcca gggttttacg gggcgaaccc
    10201 tgcaggaaaa gaaaaattat tgggccgtgg gggaagcgac attaccggcg cgatactggc
    10261 gaagatgttg caagcggaaa gttatgagaa ttggacggat gtttcaggaa tcatgatggc
    10321 tgatccgcga atcatcgatc atcctaaaat catcgaggaa atctctttta gagaactgag
    10381 agagatggct tatatggggg ctaacgttct tcatgaagca gctgttttcc cagttcaaga
    10441 ggctgatatc cccatccaaa taaaaaatac caatgatcct ttcgctcaag ggacaaaaat
    10501 atcgaatcac gaaatagaaa aggaaaatgg actgacagga atagctggac gcaaggattt
    10561 tctttccatc actttattta aacgacatat gtccgatgaa atcgggttta tctggaaagc
    10621 aatgagcatt tttgctaaac atgagatatc aatcgaacat attccttcag ggatcgacaa
    10681 tatcggagtg atcgtctcag cagaagcgat tgccgataaa ttatttctca tcacgaaaga
    10741 attaaaagaa acacttggcg tggaagaaat cgtcgtgatt gaagacttag ctttgatctc
    10801 tgtcgttggc ggaccacata aagaattgat cggtttatct ggaaaagtgt tatcgatatt
    10861 gaacaaatta gaaattcgca catcgatctt atcacaagga gcacaggagt tgaatctgat
    10921 catcggtgta ccgaataacc aatatgaaac agtagtgaag ggtatctatg aagggatggt
    10981 gaatacggat gctgaaagaa tatcgaatgg cactccatca aattcctgaa atcggatttc
    11041 atgaattcaa gacaaaaaaa tatttatatg aacaagtaaa aaacagcggg gccgttatcc
    11101 atgaaatcgg cgaaacagga ctactccttt attttgataa tcagcaagaa gaaacgattg
    11161 cttttcgaac agatatcgat gcactgccag tcaaagaaga aacgaatctc tcttttgctt
    11221 ctaagcatga agggtatatg catgcatgtg gtcatgacgg acatatggcg atgcttttag
    11281 ggttgactga ctttataact aaacacattg aggatcttat ttataatgta gtactgatct
    11341 atcagccatc agaagaaatt tccggtggcg cacaaagcgt tattcagtca ggattgttgg
    11401 ataaatatga agtacaagca atatttggct ttcatctatg gcctggacta gctaagggag
    11461 aagttttctc tcgaccagga cctttgatgg cacaaagcag tgaaacagac attatcatta
    11521 aaggccagtc tgcacatatt gcttctagtg aaaaaggaat cgatagtctg gaggcagctg
    11581 tacgattttt gaagaatgtt tatgattttg accggcaatt accggcagag tggaatcatc
    11641 taatgaaatt tggccaaatc caaggtggaa cgatccgaaa tgttttagct ggagaagtta
    11701 ttgtatctgg aagtatccgt tcttacagtt cagatatgca aaattatttg aagaggggat
    11761 tagaccattt agcagaacag tttcactcta cagctactat ttcttttcac tataatgacg
    11821 gctatccagc tgtaatcaac catagaggct tatatgcagc actgttagat tcaaacaaac
    11881 tacatgaatt agatgctcca gttcttcaag ccgaagattt tggcatatat acgcaacaat
    11941 atccatgtgt atttttcttt ttaggtgtcg gtgatacccc tgctttacat gatccgacgt
    12001 tcgattttga tatggatgtt ttagaaaatg gtgtagaatg gtacaaaacg attcttttta
    12061 cagaaaatct tcttgtaaaa atcgatagca gatcaaaaga ggagcgagta tataatgatg
    12121 aatttatcca atcgatttag tcccaggctt tctagaatag aagtatcaaa aatacgacaa
    12181 ttcgatcagc aaatatcgtc gataccagat gtgatcaaac tcaccctggg agaaccggat
    12241 tttccaactc ctaaacatgt caaacaagcc ggaatagcag cgattgaaga agacttttct
    12301 cactataccg gaatgagagg attagaggaa ctgcgggaag cggcttgtat gtttcagcaa
    12361 cagcgttatg gattaactta tgatccgcaa acggaagttt tgacgacagt tggtgcaacg
    12421 gaagcgattg cctctgcgtt gttatctgtt ttggaagaag gagacaaggt tcttattcca
    12481 gcgcctgctt attcaggata tcagccatta gtggaactag ctggtgctga attgatcccg
    12541 atagatactt ctgatacagg gtttgtctgt cagccggaac aatttgaacg agcatttgaa
    12601 caatatggat cagctgtcaa agcagtcatt ttaaactatc ctaacaatcc tactgggacg
    12661 acattgtctg caaaacaatt gaaagcaatc gctgaggttt taaaaaaata tccggtattt
    12721 gttataagtg atgaagtata tgctgaattg acttatagtg gaacgcatat gtccatagct
    12781 acttatcttc cagaacaaac aatcgtgata agcgggttat ccaagtcaca tgcgatgact
    12841 ggttggcgag tgggctttat ttttgctcaa aaagccctta ttgacgaact aattaaagtc
    12901 catcaatatc tggtgactgc cgctacaacg atgtcgcaaa aagctgcagc tgaagcgcta
    12961 ataaatgggg tgaaagatag cgagaatatg aaagagcaat atcaaacacg aagagactat
    13021 ctggtccagc aattggcgcc tttaggattt gaagtgaccc agccaaacgg tgcattttac
    13081 ttgttttgca aactcccagc tgccattcaa actgactctt ggcagttttg tgtagaatta
    13141 gcggaacagg caaaagttgc gtgtatccca ggaattgcat ttggcccaga aggagaaggt
    13201 tatatccgga tttcttatgc tagcagcatg gaaaaattac atgaggcctg caaacgaatc
    13261 aaagactttt taacagaaca gtgattcata gattttatca aaaaaacaat cgttaatttt
    13321 gcggtatatt ctgcaaaatt aacgattgtt ttttaaattt agttcaaatg aacgcgtttc
    13381 ttttgattca taactaatgt aatgttaagt ttaaattgtt tagaatgatt ttaaaagaat
    13441 attcaaggag gtttcatcaa tggaaaaaat caaagttgtc attgtaggtg catctcatgg
    13501 agggcatcaa tcaatcttgg aactattgac acgatacggt gaaaatgtag atatcacgct
    13561 atttgaagca ggagactata tttccttcat gtcatgtggt atggagctgt atttagaaga
    13621 caaggtaaca gatgtaaatg atgtacgtaa tttcagacca gaaaactttc cgcaatccaa
    13681 tgttcatatt ttaaataatc acgaagtaaa aacgatcgat gccgataaaa aaacagtaac
    13741 ggttactagc gtatcagata acgaaacaaa agaatatcct tatgacaaat tgattttgag
    13801 ttctggtgtc aaaccaaaca atctgccagt accaggagca gatctagaaa atgtctactt
    13861 gatgcgtgga tacaattggg caaccaaaat caaagaaaaa ttaaatgatc cggctattaa
    13921 aaaaatcgct gtcgtaggtg cgggttacat tgggatcgaa gcagcagaag caagccgaaa
    13981 agctgggaaa gaagtcgtat tgcttgatgt gatcgataga cctttaggca cttatttaga
    14041 tgctgagatg acagatattt tagaacaaca cctaaatgaa aacggtattg aagttttgac
    14101 aaatgcaaaa atcgaagctt ttactggtaa cggaaaagtt gaggcaatca aaacaagtga
    14161 aaaagaaatc ccagcagatc tagtcattca agctgccggt gtgaaggcaa atacagaatg
    14221 gttaaaaggg atcgtcgact tagatgaacg tggctggatc caaacaaatg aatacttgca
    14281 aacgaatctt ccagatgtgt atgcagtagg agatgctaca cttgcttatt ctatcccagc
    14341 acgcaaaaaa atgccgatcg ctttagcgac tgttgcacgt agagaagcac gttatgtagt
    14401 aaaacatctt tttgaagaag taccaaacaa accgttcggc ggagtcgtag gttcctctgc
    14461 attaagtgtc tttgactatc attttgcagc aagcggattg aatagcttta cagcagcaaa
    14521 agcaggagta gatgtacgag tgtcttatta tgaagatacg ttacgaccaa aatatgtacc
    14581 agaagaacaa ggaaatccaa aagtgtccat ccaattattc tcggatccaa tgacccatca
    14641 attgctagga ggagcagtat tatctaccta tgatgttaca ggtcaaggaa atgtattggc
    14701 actagcgatc caaaacaaac tgactttaga agaactagca gaagctgact tcttcttcca
    14761 gccaggcttt gaccgacaat ggagcatgtt gaatctagcc gctcaacaag cgttaggaga
    14821 agaaccattt gtagaataag aaaacgaaat atttgaaaag aggttgtgaa aaagctgcct
    14881 tgcatcaagt aataagaaca gccaagtaaa aacagcttct tatgttttta acttggctgg
    14941 acttattacc gcagatgcaa gcttttgaac accgtttatt ttcaaaaaag ggactgtgac
    15001 acgatttgtg taccgacccc caaaagttag accaaaaaat ctaacttttg gaggtcggta
    15061 ttttttatgg ttaaatatac ttttgaactt aaattaaaga tcgttcatga ttatttggat
    15121 ggcaaaggcg attggaccgt aaaaatccag atcaagagat tgaagcggaa atgcttaaaa
    15181 ttcgggagaa gcacaaggat tatggctgtt tacggatgac caatgaacta agaaaccgcg
    15241 gtttctctat caataaaaag aaagttcagc gcttgatcaa gaagctagga ataaaagtaa
    15301 cggcatacac gcgtaaatca cgtcgctaca attcttatcg aggaaaagtt ggagcagtag
    15361 ccaaaaatcg gatccatcgt cgtttctaca ccagtatctg ccatcagaaa atcacgacgg
    15421 atacaactga atttaaatac catgaagtgg atgccaaagg cattatccgt caaaagaaat
    15481 tgtatctaga tccttttatg gatatgttca atagtgagat tttatcctat cgtatctctg
    15541 aaaagcccaa tgcattagcg gtaatggaag gtttggagga agctatccag accactaacg
    15601 attgtcccta tcgtcgtacg tttcactcag atcaaggttg ggcgtatcaa atgaaagctt
    15661 atagaaacaa attgaaggag tacaaaatct ttcaaagcat gtctcggaaa gggaactgct
    15721 tagataattc acttatggag aatttttttg gcttattaaa acaagagatt tttcacggga
    15781 aagtttataa ctgtttcgag gaattaaaat cagccatcga tagctatatc tattactaca
    15841 ataatgaacg gataaaacag aaattaaact ggcaaagtct cgtccaattt cgtaaaacaa
    15901 ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa aaaaggagtg gatttctcca
    15961 ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca cagtcctttt tttagtaaaa
    16021 ggatacattt cttccttgta tattccatgc gtgttcgtga gaaagcatat ataatttaat
    16081 taacagatag ttagggggag aaaaaatgat tttttcaatt acaatgaaac tggtgttcgg
    16141 gttgatcggt ttattattag tggtacgttt gcttgggaag aaatccatgt cagaaatcac
    16201 accgtttgat ttagtctata cgcttgtttt aggtgggatc ttagaagaat caacctatga
    16261 tgacaatgtc catgtagggc atgtcctatt tgccattgcg ctttgggcag taatgattta
    16321 tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat cgttgggtca aaggcgagcc
    16381 atctgttcta atcaaagacg gcgtcatcaa catgacagag ttgacaaata accatatcga
    16441 gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc ttttttcttg aaaatgccaa
    16501 acatgttatc ctagagaatg ccggtcaaat gagtgtattg aaaaaatcag atgaagacaa
    16561 agctttatcg atcctgcttg tagatgaagg gcaaattcag cataaagtgc ttcagtccaa
    16621 tcaattgact gaagcatggc ttatggagaa cttgaagaaa gaaggctatg cagatgtaaa
    16681 acagctgatt tatgttgaat ggtcagaaga aaaagggctc tacatactaa ataaagaaga
    16741 cgtcatgcat gaatcttacc gaatagatgg atagatagac agaggttgtg aaatcagcgc
    16801 cttggcttgt tactcaaaac taagcgactt tttcacaacc tctgatatct aatatacgtt
    16861 gttccagaag ttgcttcttc gaaaaataag ccaaaattcc acaaaaattt aagaagcaat
    16921 tttcgaaaaa tcctttctta ttttttgaag ttgatcactt ctgtcacaac ctctcatgtc
    16981 acaaaccatt tttttgtttc ctttaactca atataccgta cgtcttccca caatatcggc
    17041 tgatggtcaa tcataaagta atcttcatag gcttcaccaa tgaagtgccc ttcgacctca
    17101 tccaagagtc ttccaaattc atcttttaaa ttgagctgaa tgattactgc tttacgagat
    17161 aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg tcatttgttg tttaggaaga
    17221 ggctgtttgc gtgcttcttc ttcatttttt ttgataccgt tgactagttc ttccatcgca
    17281 aaagcagtcc cccattttaa tccaaatggc cgatctcgat actcgttata gtcaatgaat
    17341 ttttttgctg tccgtctcat cttttccacc ttctaatcca ctcataccac ctgcatgccc
    17401 gccaacgaga gaactacgtg cgatggcgcg tcctccttgc aagagactat gcgcatggat
    17461 gattgattga aagccgtatt tttttctaat cgtatcgaca acaaaatcaa ctttcgcttc
    17521 atttatctgc ttttcaggat cttcaaaaag gttaagctgt aaacctgtcg cgtatacgag
    17581 gtcggaacag ttcacgccta cacgccgaat atcctggtag tggtaatgct ggtggaaaat
    17641 ggtcaataaa gcatctgcta gatctctgct agcatttgtc gcttcgattt tcatttgctg
    17701 gtgaaacccg gtcttgccat ttggatcaag atagcctaaa gagtatccta cccataagct
    17761 gactacttgt gtttttgctg cagatcgtct caagcgagtg ccgacttggt cggccatttc
    17821 tttgataacg atctcgattt cttctcgtct tgtataatct ctatctagga tttgactatt
    17881 tccgatactt tttgattttg gtgtatattc ttgtcccaaa aaacttcgat cgatgcccca
    17941 agcatgggca taaagctgag taccgatgac ccctagcttg cttttcaagt gataataatc
    18001 cgcgtgagct aaatcataaa cagaatgtat acccatttgt ttcagacgtt ttgctgttcg
    18061 tttgccgatt ccccaaaagt cagtgatatc tgagattttc cataactttt ctggtacatc
    18121 ttcataacgc cattcagcaa acatttgctt tccgtctttt gagccattgt ctaaggctag
    18181 tttagcaagt agcgggttat cgccaattcc tatagtcgtg tagattccgg tctgctcaaa
    18241 cacatcttta tggatcagtt tagccatgtc gtacgcattt gttttaccaa agagtgccat
    18301 gctatttgtt acatcaagga agctttcatc gacggaatag acatgatggt tcgcttcgtc
    18361 tgcatatttt ttatagatag aattgatttc tctgttcttt tccatataat aggccatcct
    18421 tggggcaaca atatataaat cacttggata ggggaaggga agatctctgg cacggctgat
    18481 attggtgatg ccgtaagctt tttttgctgc aggactggaa gccaagatta atccgctacc
    18541 ccgtgtttct gtcgaatcgg acggatagga catgactact aatttagttg taaggggatc
    18601 aagatccttt tcaacgcact ctacggagga tagcgatagg taatcctttg atgcaatctc
    18661 cagattttcc cccgctccac accgtacgtg cgactttcac cgcatacggc gttccatcaa
    18721 agtttactaa cagtatcata cagttataga ttcagcgaca attcacgatt cttagctttt
    18781 ttgcgaaact ggttgattat ctcaagttga gcacttgtaa ctctcatgtt ttgtatgaga
    18841 agtgatgctc ttgttttatc ctcttcatga ataagtgagt gaatgttccg gtggacaatg
    18901 accagatttt gataattgtc tttcccacct agatttttag ggacaatacg gtggcagtat
    18961 atgtctgcta gctctaagac ttctttcgtt actcggcaac ggccgacttg ggaagagtac
    19021 ttggatacac gattgtctct aaactcaatg ctttcattag gattagacat gttcatgagt
    19081 tggttgataa tatcgattgg gaaagtaaga tacctgtgta tcagcacacg accttcgggc
    19141 gtgtatttac aggttcctat cttgggcagg gaggtgtggc tatgttttat gaatccaaaa
    19201 ggaagcatag gaacaccatt aagccacctc aactgctttg accgagcgta atttttttta
    19261 ataaaatcac tcggtggagg accctttctc ttaatatcta gtcgattttt gatgataatc
    19321 attaggcgtt gatttattct tgggcagtcc acactgatgt gggttgcctt tttataatat
    19381 tgatggatac ctactaccat tgagttataa atacttaact gtttttgaag ttcaacttgg
    19441 gtaggtgaat gttgaatcac cttaatttgt tttgctaact tattagatgc tgcactcatg
    19501 gctttggcgc acatgtgcgt ttcaatcaca aagctttttc ttttgcgtac cagtttcatt
    19561 gtgaatccga gaaaatcaga tttctgtttc tttagattca ctacctttga tttttcagca
    19621 cttatatcaa gtttcagtcg gtcttttaac cataatttag tggctagaaa gattttgtct
    19681 gcgtcacttc gttttctaca gaagattttg aagtcatctg cgtatctaac aatataaatc
    19741 tcttttagtt tcgaagcacg cagtgctcga tatttgttgc tcttaatcca ttgctttctt
    19801 gtttgatgat aacaatcgta gtttttccta gtcgggtgtg tttcccattg agaagatatc
    19861 caccagtcca gttcattcaa aacaacattg gcaagaagtg gagagagaac accgccttgc
    19921 ggggttcctt tctttggatg ttcaatgcgt ccatccctat gaataatagg tgctttaagc
    19981 attgctcgga taacacctag aagccattta tcacgtaccc ctaatgtcca aaactgttta
    20041 ataagttttg aatggtttac gttatcaaag aatccttcta tgtctatgtc tactacaaaa
    20101 gttagttttg aaagttgcgc cattcgtact gcttgagcga atgcatgatg tgccgaccgg
    20161 ttaggtcgga aaccatagtt cttatcatga aactttgctt ccatgatcgg ttctaaaact
    20221 tgtagtagac actgttgtat gattctatcc catattgttg gtatacctag tggtctagtt
    20281 ttcccatttg gcttaggaat atctactcgt ttaactggtt gcggtttata ttctgaaaat
    20341 tttgtttgaa cagtttttat aaactcgata ttcggtattg cttttaaatc atcaatattc
    20401 tttttgtcga cgcctgggga agtactacca gaatttcctt taacattccg aaatgccaat
    20461 agaatgttat taggagaagt gacaatttcc ataaggttac tgaaaatttt gttctcgcta
    20521 ctctctttgt aaagagaatc aaagctatca ataagaccat aatattccat atggcgaatt
    20581 gaatgtgatg ctgatacgtt ttccatagca ccgcctcctt tcggacgtcg gcgtttattt
    20641 tgtcatactc gattctatgg attgtatcat aactgttagt aaagcaaatt gacttgtggc
    20701 tatccctcca cagcttatta tcactgcttc ataggtactg tgccactact ctcactagtg
    20761 taaatgagct tattattctt cgtctcaacc gtttcaaagg aagttagtcc tccacgacac
    20821 tagctttcaa cgttccaatg attttatccc tgcatttact tttaggcgct cactctgaac
    20881 ctgtaacttt ccaatgccta ctacattgca cggttgttca tatctacgat tcttacttaa
    20941 ccgcaagcta caccctttgt cacagtaata tttgtgcggg taagatacat ttctgtaccc
    21001 caagcttata gattcgtaca ttcgcgagtt cgtcagtgca gctgcacatt ctcaccatga
    21061 gtaatttctg gactcccggc ctataggtta caccattcac cgctgaacag ctttcgattg
    21121 cataatgcaa ctgcggtaac tctcagccga ctttaccgag cttttgacaa ttcctattct
    21181 aacttaaggt attgccaatc ggagtatcag agggagcgct tcaggtcgtt acaccgtcat
    21241 ttcactcctc aaatcattag ttctacacaa gaaaatcttg tgtgcctaac cttttcagtt
    21301 aggaacgttt cgcaccgtaa aaagatttgc agtcaataca taaaatatct cttgaaggtt
    21361 ctttttcata aacaaatacc ggattttgat tcgcccacat aacaatcacc tcttcaacac
    21421 aattagaaca cacgttctct ttccgtgtca ataaaaaaca gcaattttca aatacgagca
    21481 aaaggctcac atttggaaat tgctgagagg ttatttttat ctatttgttt ttagctgaga
    21541 tcgttgattt ttttatcaaa catgaacagc ttctggatcg atctttgttg tcccatttcc
    21601 aatgtgtgca acataaaatt ccggagcata gccgacaact ttcatgtatt catcatagac
    21661 attgtttttg aaggcaggta tattttcttc tttgacaaga gcaatcgcac agccaccaaa
    21721 tccagctcct gtcattcgtg cacctaagac accttcttgt ttttgagcag catctactag
    21781 tgtatctaat tcgatcccag ttacttcata atcatagcga agagagtggt gagaatcatt
    21841 taacagttga ccaaatgctt ctaagttccc agcttctaat tcagcttttg ccttcaaagt
    21901 ccgctgattt tcagaaacgg catggcgagc tctgcgtatc aatgtatcat cgccgatttg
    21961 gtcaatagtt gattcaaatt cttcttcatc taagtctcct aaagaagaga taggcaaagt
    22021 tttttgcaaa cgtgccaagg cttcttcgca ttcgctacgg cgttcattgt attttgaatc
    22081 tgccaattcc cgccgcttat tcgtattcat gatgacgatt gcataaccat ctagtttcac
    22141 tggaaccatt tcgtatttca gcgtatttgt atctaataag attgcatgat ctagctcacc
    22201 gaagccgatg gcaaactgat ccatgatacc tgaattgaca ccgatgaatt cattttctac
    22261 ttttttacct gtttggacta gttccaagcg atctgttttt aaatcaaaca gatcttctaa
    22321 tacaacacct actaataatt ctaatgaagc gctactggaa agtcctgcac cattagggat
    22381 tgttccttcc actaataact caaacccatg atcgattgag tgtccagctt cttttaattt
    22441 aaggaccatt ccttttacgt aatttgccca gtttgctttt ttatcatatt ctagctcatc
    22501 taaagtaaaa ctaatgacac cgatatcgtc aaagtttgtg gaataaacta atattttatt
    22561 atcgtctcga ggtgctgcta caccttgcgt tccataagtg atggaagcgg ggaagacatg
    22621 gcctccattg taatctgtgt gttcaccaat caaattgatg cgtcctggtg agaagtattg
    22681 tgtagttttt ttaggtccga atgtttcggc aaattttgtg tttaagcttc ttttgatttc
    22741 catgatgagt tattcctttc ttgttttgat tttgaattct gtcactgttt caaatactga
    22801 tccggctttt aaatgaatcg aaccaaatgc tgagaagcgc tctgcacctg gagctgtttg
    22861 agtctcaaat gtgatgccac cgtgatgtgc cagttttcgg ttgcgcattt ctggtgtttc
    22921 tgtgccgaaa tttgcagtga aaataaccac actagaagca tctgtagcaa tatctacttg
    22981 gattctttta tcggggctag tcaagcgagc ggcttcttta cccaagccgg tttcttttaa
    23041 gaaaaatgga tgatcgattc cgtcaacaag atttttttga tccaaatcac tagcaaaaac
    23101 ggacgctaat tttttaggta tttgaaaatc gaaagcactt cctgcagcat tttcttttac
    23161 ccctatagga atactatctg ttcgcaaagg agcataagct tcgctattga gccaaagctc
    23221 atgttgatcg attgactgag aagcatctcc cgtcaagttg aagtaaacat gatttgtcgg
    23281 attgaataaa gtatcttggt cactggtgcc gcgagaggtc actcgccaga tattatcttt
    23341 tgtcaaagta tagcggattt ccacatccat tgtacctgga aaaccatgtt ctccgtcggg
    23401 acttgtagta gtaaaaatga cagaagcttc attttcgcca ttcaaaatga cataagacca
    23461 tttttttaat tcaaatccag gagcaccacc atgcagatta tgtccagttt ttggatctgt
    23521 ggctaattgg taagtttttc cattgagaga aaagcggcca ttttcgattc tccctgcggt
    23581 gcgaccgata gaagcaccga tatacggatc tttttcgata tattcttcag cggtgtcaaa
    23641 tcccaaaact aattctcgat catttgattt taaactgacg attctagcac ctaaatcaga
    23701 gatagaaagt gctagcttgt ttttgttctc caaggttatc aagtgataac cttggccaaa
    23761 atctttttct gtaatcttca ttttcaagat cctttcttaa tgggaaggaa ctactgcatc
    23821 gtgaagttca tcttccattg tatcagctgg agccaatttg ttttccaatt tctcaacgat
    23881 ttgtgcatgt tttttctctg tcaatgtaat cttccaagca aaaataatag cggagaaaat
    23941 catcaaagca gcaggagcat agaatgcata agctttgaaa gtcgttacgc catgagcagt
    24001 gatatcagca gcagtagcat taccagtcat cccagaagcg atagcgacaa accctacgat
    24061 cccgttagac aaagcaccag cgattttatc tagtaaaggg cgaattgata gagtaacagc
    24121 ttcgttacgg ataccatttt tccattgacc atattcaaca gagtctgtga tcgtcatcaa
    24181 agcggataag aaaatcaatt gttgagggaa gtagaacaat actagcccga tgataacgat
    24241 tggcaaactt gaacctgcga tcgtaaagaa aaagtaagaa gaaatcatca ttgcgatccc
    24301 tccaaggtaa acgtagcgac gagagatgac gcgtgtaagc attgggaata gtggaacagc
    24361 tactaaacca agtaaggcag caactagacc aacgatccaa aattcagttg gttggccaag
    24421 tacatatttg aagaagtaga ataatacggc agttgttgct acattggcaa tcgcataagc
    24481 gatataagca agggcaagcc acatcaactg atcattttga gcaactgctt tgaacacatc
    24541 tttgatccca gctttttcat tttgctgacg gatcgcagta tcgacttctt ttgtgcccaa
    24601 ggcagtgata atcgcagtac cgcctgaaat aacagcagca atcacaccga accagaacca
    24661 gcctgaagcg ccttcaatat gtttatgagt aacaagatag gtaaagaaag taacgatagg
    24721 gacaacgact agagtagtac catttgcacc tagagaagag ccgaaacgag caaacgtagc
    24781 aaatttttca cgttcctttg tttccgtact caaagctgga atcattgacc aaaaagcgat
    24841 atccttaaat gaataaaaac tatccaataa gatgaaaacg attgcaaata atatgataaa
    24901 taaagtcgta ttatgagtag ctaagccaaa gaaattggta aagattgcta ccaagagtac
    24961 ggaactaaca acgccgccga taactaacca tggtttgaat ttaccgtatt ttgtacgagt
    25021 attatcgatg atgccaccaa tcaaaggatc aaaaataatt tcaactaagc ggatacctac
    25081 aactaagctt gtaactgtag caatcatttt tgcattcgtt gccttatctg ttcctgcgaa
    25141 catctggctt gtcacgaata ccataaaata agtgcttaat gtaacataga atgtgtcgtg
    25201 tccaaaagcg cctaaagcgt aggacacacg ttggatcatt ttgcttttca taatctgtat
    25261 tcctctcctg ttcaatatat aatactaagt aaaccggtta caacgaataa caaagatctt
    25321 ttaatgactt aaacttaaca agaaatcgct tcctttttaa tatatttctg tgacttttat
    25381 ttaacttttt gttgcattat actaaaggag taaggaggga tagacgtgga gcaatcgatt
    25441 tttttaaaaa aggaacatca acaagtagaa aaagaattgt attttgattt ttgtggtttc
    25501 tctaaaacga tgccgtttca ttcttttggt cctgctattc gcaatgatta catcctgcat
    25561 gtcgtgatgg aaggcaaagg atcttatcat gtgaaaaatc aacaattcca attgaaaaaa
    25621 ggtgatctgt tcttgattcg tccaggagac tcgacgtttt acttatcaga tggagaagat
    25681 ccgtggatgt attgctggct ttcatttggt gggagtgctg cagaagaaat cattcggcag
    25741 tcgcttttca gagaagacca atacacgatg gtctcttctg acatacaaaa atatatcgac
    25801 attattttag aatgcatgaa agatacggaa gaaaccttgg aaaatgaatt acagttaaca
    25861 gcattaacct accgtttttt atcagtcctt ttaaaagatg gcggaaaggt cagcggaggt
    25921 gtacaaaagg ttcattcctc tttagctgtt gaaacagtca aatacatcga ggcacattat
    25981 gctgaaaaat tgtctgttga ggaaatcgcc cagcatttag cggtcaatcg gagccatttg
    26041 tcgcgagtat tcaaaaatca tatgggcacc agtatcaagg aatatttgat cggggtacgg
    26101 atcaatcgag gggcgtttct tctttctctg acggatgaat ccgtggaaag tattgcctat
    26161 caagtagggt tcaatagtct agtcgtattt agccgaatgt tcaaaaagag taccggagaa
    26221 acggctacga actatcgtaa acgtatgaaa aacgaaaatt ttaagaatat tgctttggat
    26281 accttgaaaa aacagttgga aaaacaaacc gcagtttctt ggacaacctg attagtctgg
    26341 ttaaaatgac aagcatcggc aaaagaaact tgtggcggtt atgctacact gtaaagcgaa
    26401 gactaaaaag gaggaaaagg gatgcgtaca cttatcatca ttagccatcc aacgatcgaa
    26461 gaatctttaa atcagcaatt tttcaaagaa gcttctgctg gtttaccagc tacttggcat
    26521 catttggaat caagttatcc agacggaaaa atagatatag agactgaact acagctcttg
    26581 gcccagcatg atcggatcat tttccagttt ccgttttact ggtatagttc tcctgctcat
    26641 ttaaaaattt ggcaagataa tgtcttggaa cgagcagcac atgtattaaa agggaaagaa
    26701 ctaggaatcg tattgacaac aggtgtggcg gaaaaagaat accaagctgg aggaaaagaa
    26761 gaatatacga tttccgaatt tttgaggccg tatcagcgaa tcgcaaataa attccatatg
    26821 acctatcttc cgccattcgt tttagcacaa tttatgtatt tatcccagga aaaacgttgg
    26881 gagaagctaa ttgcttatca gcagtatctc tcattggaag gcaaaccatc gctgactcag
    26941 cggattgact ggtttattca aagagtacag gaaaatcaga aaatgcagga agaagaatct
    27001 gaaaaacaag catatatcgt agaagcactg actgaggcaa aagagcagat cgaagacttg
    27061 acctttacac tgcaagaaat gaaaggaact tcattatgac aaatgattgg ctgatccaac
    27121 aattagatga attaagcgaa aaatcagaat atcaagaccg tgcgctctta tatgaaataa
    27181 agaaactgat ggctgagata gacgaacgaa caatgcagct gcaaggagaa atcgacggac
    27241 aatcttggaa tcatctcaac tggtgaaatt ttcttataaa taacaaagat aaaaatgtgc
    27301 acagcgacaa ttatttgcta caataagaat atgaagcgtt tgataacgct attatacata
    27361 aaaattggtg gtgaaaaaaa tgtatgatga aaatgagtgg ggagaaaatg ttcggatgac
    27421 ccgaagaaga cagcaaaaac aggcagctcg taagcggatg atcatgattg gggcagcagt
    27481 tgccgtgttt ttgatcatag caggaggagt tgcgggtcta tattttcatg gaaaaaattc
    27541 gtcagaagcg aaaagtacga ccataacgga aacaacgaca aagaaaacag agacgaaaca
    27601 aacaagtgag tcatcaacta aaacaaaaga gacacaaact tctgaagaaa aaacagcaaa
    27661 tggtttgcca gagcaacttc aagcaatcgt aaatgattat tcgaaaaaga tcgaagaaaa
    27721 gacgcctgca ttgattgaag aataccagac agaaattcag ggaaatcaag agggaatagc
    27781 tggtttatca gcagttgcta accaaaaagc acgtgagctt caagcaatct ccgacgaagg
    27841 gatcagaaaa ttacgtgcag cgtatcaggc agcagaaaat aaagacggtg tagacttaga
    27901 tactttgatc aatcaattat cggctaatta tacgaatcat gtcgctaaga tttccgatat
    27961 ttatttgcag actagcgcct ctcttcaagc agagtcaaca agcacacaag acacaacatc
    28021 ttctgattct gagacagcag agtcggtaga agcttctgaa atgcaagctc gaacaacaca
    28081 agacacaaca gattcctctg aaactaatac caacagcgcg acttcacagg ctgcgacaac
    28141 cgtagttttg gaaggagaag gtccaaatca aatagccgaa cgaactggcg taccagtaga
    28201 aacgatcttg tcgctgaatg ggatgagcat ggagaattat ttcctgactc ccggtgagac
    28261 gctaaaattg aattgataaa agcaataaaa aagaacgaag cttccactaa ggtgaagctt
    28321 cgttcttttt ttattttccg gttctttttt cgcgtacaaa gtaatggatc gtcatgtaaa
    28381 gcaagaaaac gagtccaata atcaatgaga ttctcgtttc aggattgata aacatgaaaa
    28441 tcaatacgat agctaaaaaa gcaagtgtca cataattcgt ataaggagat agtggcattt
    28501 taaaaggatg atcatgcatt ttatctgcgt gcttcttttt gaagcgaatc tcgctgatca
    28561 aaatcactac ccaaggaacc ataccaggca aaatacttga gctgtatacg aaaacgaaaa
    28621 tattttctga ctggttgatg aacattggta gaagataatt taagatcaga ccaattaaga
    28681 ttccacctga gattgctacg acaggataaa aaggcgcacc gtgacgagat agtttcagaa
    28741 attttttaga catctttcca tttatggcaa gtgtatagac catacgactt gcgctgaaaa
    28801 tccctgaatt gcaacctgat aatgccgctg taatcacgac aaaattaatc agtcctgcag
    28861 caaatgtaat gccgacttta gaaaaagttt gtacaaaagg tgaaccaatc tcactcaatt
    28921 gattccacgg atagatactc acaatgataa aaatagcacc aatataaaaa atcaagattc
    28981 gaccgatagt ggactggaca gcttcaatga tcgtcttttt aggattctct gcttcaccag
    29041 cagtcattcc gatcagttcg attccttgat aggaagcaac aacgatcgat aatgcaaaga
    29101 aaaatccttt gacgcctcca gtgaagaatc caccattttt ccaaagattt gaaatcccta
    29161 ctgcctgacc atgattacca aatccaaata agattacccc aagacctgca atgatcatca
    29221 aaatgatcgt tatgactttg atgatcgaaa accaaaattc taattcgcca aacgccttga
    29281 cagaaataag atttgccagc ataagaaaca agacgacaat gattccggga ataattgccg
    29341 gcaaatcagg ccaccaataa ttcatataag atcctacagc aatcacttca cttattccta
    29401 cgacaatata ttgaaaaata ttactccaag cggtcaagta gccagccaca ggatggatgt
    29461 actcgctcgc gtaatttgca aaagaaccag tcgaaggatc aacgtaaagc atttcgccta
    29521 aagcacgcat aatcaaatac aaaaagaatc ctgcaatcgc ataggctccc atcactgagg
    29581 gccctgtcca acgtatggtt gaggaggcac ccataaacag accgacaccg atcgttccac
    29641 ctagtgcgat catttggata tgacgggcac taagacttcg agttaacttt tcttcttcca
    29701 tacaaaaact cctttcgttg ttgagtcaac aagaaaaaat aatcaaacgt ttcaacacat
    29761 gtttttcatt attaggttag ccttattgaa ctcttgatgt gattctacag aaaattttca
    29821 taaaatgcga ggaaaattcg aaaaaaactt tttcatcatt ctacttgaaa atgctttcca
    29881 ttttagttaa actatattta aataaaaagt taggtaaacc taaaaaggag tgtaagattt
    29941 ggaacgtacg gccattgtaa ttcaagacct ttcagccgct tatcaaggga aaactgtttt
    30001 gaaaactatc aacttgacga taaatccaca aaaaattacc ggtattatcg gaccaaacgg
    30061 tgcaggaaaa tcaacattta tgaaatcttt gctagagttg ataccagcta ctactggtaa
    30121 agtcaccttt tctggacagc cggtaaactc agtccgtaaa aaaatagcct acgtggaaca
    30181 gcgaagtgaa ttggatcttt cctttccaat tgatgtatta ggcgttgtac ttttaggaac
    30241 atatccatct ttacgaattg gacaaagacc tgggaaaaaa gaaaaagaac gtgcaagaca
    30301 agctttgaaa aaagtaggga tggaagaata tgccaaaaga cagatcagcg aactatcggg
    30361 tggacagctt cagagagttt ttattgcaag agctctagcc caaggagcag aatggatctt
    30421 tttagatgaa ccattcgtag ggattgatgc gttaagtgaa cgaaagatct ttgacatctt
    30481 gcaggaattg aagaattcag gaaaaacgat tttgatcgtc catcatgatc ttcataaagt
    30541 agaagaatat ttcgatgagg ttattctttt aaataaacag ctgatcgctt ccggtccagt
    30601 acaagaagtc tttacatcga agaaccttca attggcctat ggtgagatca tcagacattt
    30661 agtaaaagga ggagagaaaa aatgatccaa tcctttattg atggattaat gaattatcaa
    30721 ttcctgcaat acgctttggt cacttccatg cttgtaggac ttgcttctgg agtcatcggt
    30781 tcttttatta ttttacgagg gatgtctttg atgggagacg ctatctctca cgcagttctt
    30841 ccaggtgtag ccatttctta tatgtttggt tttagttaca tctttggagc cactgctttt
    30901 gggatgctaa cagcagcagt gattggtttc gtgactcagc ggagccgatt gaaaaatgat
    30961 acagcgattg gaattgtctt tagctccttt tttgcattag ggattatctt gatttcatat
    31021 gcccagagtg cgacagattt gtatcatatt ttatttggga atgtcttagc tgttagggaa
    31081 agcgatttgt tgctgacagc actcgttagt ggaatcgtct tgatatttgt ctttttcttt
    31141 tataaagaat tgaagatcac atcattcgat ccgacaatgg caaaagctta tgggctgaac
    31201 acatcgctga tccattatct tttgatgttc tttttgacat tagtggctgt agtcagttta
    31261 cagacagtag gaacaatctt ggtgattgcc atgttgatca caccagccgc cacggcttac
    31321 ttgctaacga accatttact gaaaatgatc attacagctg caggaatcgg tatgctaagt
    31381 gcagttgtcg gtgtgttttt cagttatagt tacaattggc catcaggagc tacgatcgtg
    31441 ttagcatgta ccgcattttt tatccttgct tttttatttt ctccaacaaa aggaatttta
    31501 tttcagaaag gaagcagata gatgaaaaca aaaaaatcac tctttttaat cttggcagtt
    31561 agtttcttgg tattagccgg ttgcggaaag caggcttctg accaagcgga tgaaggaagt
    31621 aaagaaaagt tgtcagtcgt ggctaccaat tcgatcttgg cggacatggc aaaagaggtc
    31681 ggaacagatc aaatagatat ccacagtatc gtaccagtcg gaacagatcc gcatgaatat
    31741 gaagtactac cagaagacat caaaaaggca agcgatgcag atgttatttt atacaacggt
    31801 ttgaatcttg aaacaggtaa cagctggttc gataacttga tggaaacggc taaaaaagaa
    31861 gaaggaaaag attattttgc agttagcaaa aatgtagaac ctctttattt aactagcggt
    31921 gaagaacata caaaagcaga tccccatgct tggctagacc tatctaacgg aataaaatat
    31981 gtggaggaaa tcgcacgtat attctctgaa aaagatgcag aaaatgcgac actctataaa
    32041 aaaaatgcag aagcatatgt ggaaaaacta aaagaattag atacacaagc gaaggaaagt
    32101 tttgcttcta tcgaagagaa caaaaaatta ttagtaacaa gtgaaggggc attcaagtat
    32161 ttttcacgag catatgattt gccagcagct tatatatggg agatcaatac agaaagtcaa
    32221 ggtacgcctg atcaaatgaa agcgatcatt gatcagataa gagcaaaaga agtaccggtt
    32281 ttattcgtgg aaaccagtgt agactcaaga agcatggaac gggtagcaaa agaaacgggt
    32341 ttgaaaatct atgataaact gttcactgat tccatagcaa aagaaggaga acaaggagat
    32401 tcttactatc agatgatgaa atggaatatt gaaacgatcc atgaaggttt gtcacaaaca
    32461 aaagaaagct gaaaagtgca aggtctagct tgaggagcag accttgcatt ttttataaga
    32521 gatatgaaaa aaaattatgc tgtttttcgt cgtacagata ccttttttga agaaattccg
    32581 ttatagttag agtaaggaag gaaggtgtgg ctatgaattt tacacgtaaa gataaatata
    32641 cgattaaaga agaagtcttt cgattgatca gccagcagga aaataccgac aaggatcaag
    32701 accttcaatt tcttgaagca gaattagcta aattattcat agcaaatcaa aatgagacaa
    32761 cagaaccaga tgaagagctg tacataggca aatggttgtt tgatgaattt cagcctttag
    32821 atgaaaatac cggtatcggt tattttgtgt tcctttctcc agtcggcttc acacctggcg
    32881 tattagttaa acaaaacgac gaaataaccg tcaaagcatg gcctgcatta ttttcagtca
    32941 tcaaagcaga aggagtaatc aaaaagatcc agtcggccta ttataaaagt caatttattg
    33001 ccaacagcaa attaatgaat atgttttata atcgtctagt agaaattgct aggcctggga
    33061 aaatcccgca aacattcacg tacacacagc aaaaaaatct ctatgaagaa gtattgtatt
    33121 cccgcgatct gtctgagttt tcgccatggg aagaggtaag gctccatgaa ctgttaagta
    33181 caaaaccagt ttcattgaat ttttttaatg cattagataa caaaagaaaa ttaatttcaa
    33241 caaattattg ggaagtattt gctgcaagaa aaaaatggat ggaagaaaag aagattgccg
    33301 atcagcagat ccagtttgtc cagctgaaaa aagaaaaact atattatggg ttatacagcc
    33361 gttaacagca agcgaggaag accatgacat taaaagaaga aatcatacaa gaaagcaaac
    33421 gattaggaat tgacaaaatc gggttcacca cggcggaacc ttttgattca ttaaaagaat
    33481 cgttggaaga acaaaaagca gctggccata cttctggctt tgaacatcca aatatcgatg
    33541 agcgtcttta tccagaaatg acatttgatc agccgaaatc gatcatttcc attgcacttg
    33601 cgtatcctac taggatccat gaagaagtgc ctagggatga aaaacgcggg cagtttgctc
    33661 gtgcttcttg ggggatcgat taccatgata tactcagaga ccgtttgaac cgattgatcg
    33721 aattcatcca aacaagagca gaaaaatggc aaaaagaaga ggaatggcgt ctagctccgc
    33781 aagtagatac tggagaactg atcgatgtcg ctgtagcaca gcgagctggt ttaggattta
    33841 ttggacgaaa cggattgttg atcactgaag agttcggttc atttgtctat cttggtgaga
    33901 tcgttactaa tattgtattt gagcctgata aaccaggaga atttggttgc ggtgactgta
    33961 tgcgctgcgt gactgcttgt ccgacaaaag cattgcttgg tgacggaaga atgaatgccc
    34021 agcgatgttt gtcttatcaa actcagacaa aagggatgat gccggaagaa tatcgtaaaa
    34081 aaatgcgaaa tgtcatttat ggatgtgata tctgccagtt agtctgccct tacaatcaag
    34141 gaaaagattt tcattttcat gaagagatgg aaccaaaagt agacgaaata tatccaaaat
    34201 taaagccaat gctttcgatg tctaataaag acttcaaaca gcaatttggg catttagctg
    34261 gttcatggcg tgggaagaaa cctttgcaga gaaacgcatt gattgcttta gctaatctag
    34321 gtgatcgaac ggcattgcct gagatttcag aatgtttaac agatgtccgc cctgtcatca
    34381 gaggaacagc agcttgggct attggacgtc taggaacaaa agaaccggaa aaatggcttg
    34441 atgtattaga tgaaatatta gctaaagaaa cagaagaagt cgttataaac gaattggaac
    34501 atgcccagaa attattgcgg agaaagttaa aataaaaaaa tagttaacat tattcaaagt
    34561 ttttgtccag taattgttgt aacaattact ggtttttttg tattttttac atttttttaa
    34621 gagaatttga taaaaatcaa aaattttttt gctttttttt atggattatt gcagtgaatg
    34681 ttacagaatc tgcgtttttc attcaaaaat aaaa
//
LOCUS       DAXLPC010000022        33900 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.022, whole genome shotgun sequence.
ACCESSION   DAXLPC010000022 DAXLPC010000000
VERSION     DAXLPC010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.022"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            19..1359
                     /locus_tag="ACF3UE_001017"
     CDS             19..1359
                     /locus_tag="ACF3UE_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3634468.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            1577..2020
                     /locus_tag="ACF3UE_001018"
     CDS             1577..2020
                     /locus_tag="ACF3UE_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFD3634469.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(2524..3942)
                     /gene="nhaC"
                     /locus_tag="ACF3UE_001019"
     CDS             complement(2524..3942)
                     /gene="nhaC"
                     /locus_tag="ACF3UE_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFD3634470.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(4345..5568)
                     /locus_tag="ACF3UE_001020"
     CDS             complement(4345..5568)
                     /locus_tag="ACF3UE_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFD3634471.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(5599..6438)
                     /locus_tag="ACF3UE_001021"
     CDS             complement(5599..6438)
                     /locus_tag="ACF3UE_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFD3634472.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(6455..7135)
                     /locus_tag="ACF3UE_001022"
     CDS             complement(6455..7135)
                     /locus_tag="ACF3UE_001022"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFD3634473.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(7137..8210)
                     /locus_tag="ACF3UE_001023"
     CDS             complement(7137..8210)
                     /locus_tag="ACF3UE_001023"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFD3634474.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(8266..8504)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(8547..8780)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8857..9528)
                     /locus_tag="ACF3UE_001024"
     CDS             complement(8857..9528)
                     /locus_tag="ACF3UE_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3634475.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(9615..12263)
                     /gene="mgtA"
                     /locus_tag="ACF3UE_001025"
     CDS             complement(9615..12263)
                     /gene="mgtA"
                     /locus_tag="ACF3UE_001025"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFD3634476.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(12605..12779)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            12952..13389
                     /gene="ndk"
                     /locus_tag="ACF3UE_001026"
     CDS             12952..13389
                     /gene="ndk"
                     /locus_tag="ACF3UE_001026"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFD3634477.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(13411..14277)
                     /locus_tag="ACF3UE_001027"
     CDS             complement(13411..14277)
                     /locus_tag="ACF3UE_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD3634478.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(14437..16530)
                     /locus_tag="ACF3UE_001028"
     CDS             complement(14437..16530)
                     /locus_tag="ACF3UE_001028"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFD3634479.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(17279..17902)
                     /locus_tag="ACF3UE_001029"
     CDS             complement(17279..17902)
                     /locus_tag="ACF3UE_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634480.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHVGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(18061..19458)
                     /locus_tag="ACF3UE_001030"
     CDS             complement(18061..19458)
                     /locus_tag="ACF3UE_001030"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3634481.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(19490..20461)
                     /locus_tag="ACF3UE_001031"
     CDS             complement(19490..20461)
                     /locus_tag="ACF3UE_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3634482.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            20835..21260
                     /locus_tag="ACF3UE_001032"
     CDS             20835..21260
                     /locus_tag="ACF3UE_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634483.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(21748..22449)
                     /locus_tag="ACF3UE_001033"
     CDS             complement(21748..22449)
                     /locus_tag="ACF3UE_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFD3634484.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(22465..22905)
                     /locus_tag="ACF3UE_001034"
     CDS             complement(22465..22905)
                     /locus_tag="ACF3UE_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFD3634485.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(22905..23480)
                     /locus_tag="ACF3UE_001035"
     CDS             complement(22905..23480)
                     /locus_tag="ACF3UE_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFD3634486.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            23721..23930
                     /locus_tag="ACF3UE_001036"
     CDS             23721..23930
                     /locus_tag="ACF3UE_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HFD3634487.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            complement(24328..24840)
                     /locus_tag="ACF3UE_001037"
                     /pseudo
     CDS             complement(24328..24840)
                     /locus_tag="ACF3UE_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(24966..25667)
                     /locus_tag="ACF3UE_001038"
     CDS             complement(24966..25667)
                     /locus_tag="ACF3UE_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3634488.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(25775..27217)
                     /locus_tag="ACF3UE_001039"
     CDS             complement(25775..27217)
                     /locus_tag="ACF3UE_001039"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3634489.1"
                     /translation="MQSRFSEKFLWGGATAANQLEGAYDRDGKGLSVADAMPGGKQRF
                     AIIGSEEFDWTIDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPN
                     GDEGTPNEAGLEFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYE
                     RFAQTVLERYSSKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVA
                     SSKAVKIGHELRSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGE
                     YPAYTARTHKKYGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSE
                     GNLLGGVKNPFLEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDG
                     TIIDDYRIDYLRRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDL
                     DDEGNGTLNRSKKKSFDWYKEVIASNGVNL"
     gene            complement(27231..29096)
                     /locus_tag="ACF3UE_001040"
     CDS             complement(27231..29096)
                     /locus_tag="ACF3UE_001040"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFD3634490.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(29217..30068)
                     /gene="licT"
                     /locus_tag="ACF3UE_001041"
     CDS             complement(29217..30068)
                     /gene="licT"
                     /locus_tag="ACF3UE_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFD3634491.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(30378..31091)
                     /locus_tag="ACF3UE_001042"
     CDS             complement(30378..31091)
                     /locus_tag="ACF3UE_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFD3634492.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(31159..31485)
                     /locus_tag="ACF3UE_001043"
     CDS             complement(31159..31485)
                     /locus_tag="ACF3UE_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFD3634493.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(31608..31835)
                     /locus_tag="ACF3UE_001044"
     CDS             complement(31608..31835)
                     /locus_tag="ACF3UE_001044"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFD3634494.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(32157..33410)
                     /locus_tag="ACF3UE_001045"
     CDS             complement(32157..33410)
                     /locus_tag="ACF3UE_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFD3634495.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLIGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            33471..>33900
                     /locus_tag="ACF3UE_001046"
     CDS             33471..>33900
                     /locus_tag="ACF3UE_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3634496.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGS"
BASE COUNT         9796 a         7086 c         5753 g        11265 t
ORIGIN      
        1 aaaagaaaga ggtcatttat ggaagataaa aaattgaaaa aacaacttag ctccagacat
       61 atcaccatgt tagctttagg tggagcaatc ggtgcaggtc tatttaaagg aagtggcgaa
      121 gcgattggga tcgccggccc ttctgtattg attgcttttt tgattggtgg gctgatttta
      181 tatatcgtga tgaaaggtct gggaaaaatc gttttaagcg gtggcgacac gcatcacgga
      241 ttatctggtt tgatacgccc ttatctaggt gctcattctg ctgattttac tgattgggtc
      301 tactggtcta tgtggattat caatatcatc gctgaagctg ttgcagctgc ttcctttttg
      361 cagttgtggt tcccgcacat tccagcctgg gtatttgttt ttatgttggc tgttttaact
      421 acgatcatca atctttattc ggtacggtta ttcgcagaaa cagaatattg gctggctttt
      481 gctaaaatca gtgtcattat cttactgatc atttttgcta cttatcttgt cggtcagcaa
      541 atgttgggca caggcgtttt ccctaccctt cagcaattga ctgaccatgg tgggtttact
      601 cctcatggta tgaagggaat catcagttct ttgcttgtag ttatctattc ttacggcggt
      661 tctgaactga ttgctatcac ggtaagcgaa gcagatgatc ctaaacgtgc gattcctaaa
      721 gcaatcaaag gtgtcatggg aagaatcatt tccttttaca tcattccttt gtttttgctt
      781 ttgattcttt ttccttggaa tactttagca ggcacgaatg tcagtccttt tgtgatggta
      841 tttgaaaaaa tgaatatccc atttgcagcg gatatcgtca attttgtgat tgtccttgct
      901 ttgttctcat ctatcaattc gggtgtgtat gcatcttcaa gaattttgtt cttccgtttg
      961 aaggatcgaa aaggttcctc tagaaaacta gctgttttaa acaagcatca agtaccgcaa
     1021 cgtgctgttt tattttgtac cagtgttctt tatcttggtg tagctctttc ttattttgtc
     1081 ggtgacaaat tatttggcta tctggcaggt tccctttcgt atacagtatt attgatctgg
     1141 atcattatca gtgcggcatc ctttgtactg gcactaagaa aaggaacatt atgggataaa
     1201 ggaatcagct tttttgcatt agctgtctta ggattgattt tccttggtat cctgttcacg
     1261 aactccattg gggtaactgt attgactggc ctgctttacc tgttcattta tttcagttat
     1321 caaaaaaaga atgatgcgtt cgtattgacg aatgaatgaa atcgatagaa aattttattt
     1381 tatttatgtg gaatagatgg agctattgaa gaaaggagtt gtgacaaaag tcttgttgca
     1441 actccttttt ccgaataaac agtctcatga cctcttggta aacggtgttc aaaaaccctc
     1501 tgtgcaaaat aattgattgt tctccatgct catgacatga tagaagaaag gaatgaaaaa
     1561 aaggagtttg ttttaaatga aaaagtattg gaagtttttg ttgatgatcg gtgtttcaac
     1621 ggtagttatg tttggtatga tgtacttgaa tgtctatgcg ctcgatcata tcttcttcag
     1681 tcgtacacga gtattcatgg cgttgatgat gggtgcagtc atggcagtca tcatgctgtt
     1741 gttcatgtgg aaaatgtatg aaaacaaaaa gataaatgtt atgatcttag ccgctagtct
     1801 tcttgttttt gccggttcct tgtttatggt acgaagccaa actactgtca acgacacagc
     1861 ttggatgaag gccatgattc ctcatcattc tatcgctatc ctggcaagta aacgagctga
     1921 tttaaaagat cctgaagtaa aaaaattagc ggaagaaatc attcaggcac aagaagaaga
     1981 gatcgacaaa atgaaaaaaa tgatcaaaga aatggaatga ccattatccg tccaaataaa
     2041 aaaagaggat gttccagaag ttatcagctt caagaaataa gaagaagcta cttctggaac
     2101 gccgtgaata aggggttgtg aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca
     2161 aaaatagctt ctcctatttt tcgtttggtt aggcttatta ccgcagatgc aagcttttga
     2221 acaccgttta ttaagaggtt gtaaaatcag cgttctgacc tgagtattag agagacaaat
     2281 ggaaaaatag ttcctcatat tttgccattt tttgagctaa taccgagggt cagctgattg
     2341 aacaccgttt atcgagaggt tgtgaaaaag tcgcttagtt tcgcgtatta agaaaaattt
     2401 tgtgaaatgg ctttccacat ttttgtataa atttggctta ataccgagaa actggctttt
     2461 gaataccgtt tattcgtaaa agggattgtg acaaaagtct tgtcacaatc cctttttatg
     2521 tttttattgt tctaattgcg ctgtcttgct tactgcttct tgcggtttca caaatttttt
     2581 tgagattccc caacctgtga aggcactgac catcgaaaac acaggagaaa gcaaactgaa
     2641 aaatacgaat ggcaagtaag tgagtgtagg aataccaaat gtacttgcta cgaaacttcc
     2701 ggcaattccc caaggcacta agtagttgat tactgttcca ccatcttcta gcgttctacc
     2761 taatacagtt ggatcaaatc ctgctttttc ataagtttct ttaaatgcat taccaggcag
     2821 aataacagat aggaattgtt caccaataaa aatatttact ccgatacttg tcatcaatgt
     2881 tgtaaaaatc aaatttggtg tgttcgtcat ctttcttgat actcgttcca tcacggttga
     2941 gatcaagcca aattcgatca acaatccacc taatgacaaa gttagaataa tcaatgacac
     3001 agtaggcatc atactttcga ttcctccgcg gctaagcagt gaatcgattt gttggtttcc
     3061 agtatttgaa acaaaccctg attcgatgac cccagccaac ttcgttaagg aagtttgtgg
     3121 gttttgaata aaaatcattc ctactgctac agcgatattc aacaaaatcg ttaaaattgc
     3181 cggcaccttt ttccatgcac acagtaacat taaaaataaa ggaatcagtg accagattga
     3241 aatagtaaag tttgcttcta gaacatcagt cacttcacga atagatgaaa gacttgcggc
     3301 tttacttgtg tgtcctaaaa tcatgaataa aaagaaagaa acaacaaatg ccgggacagt
     3361 tgaccacatc atatgcttga tgtgtttgaa caaatcggca tcaacaatag ctgctgctag
     3421 atttgttgat tcggataatg gagacatctt atctccaaaa acggcacctg aaacaatagc
     3481 tccaacaacc agcgctggat ttaagcctag tgttgtccca ataccgaaaa atgcaatccc
     3541 aatcgttgac ataacagtaa aggcactccc tacagcgcta cctacgattg cacacacaac
     3601 aaatacagaa gggacaaacc actggacact gatcaatttg aacccaatga ccattagagt
     3661 tggaatgatc cctgcttgta tccatacagc aatcaatgaa ccgactaaaa taaaaataaa
     3721 gattgggatg attcctggtt tgatgccatt gatgattcct tcgtgcagcc aatctgtcgg
     3781 gtatcttttt atcactgcat acaacatgac cattccgatc gctgctaaga tcgtgatatt
     3841 aggtgagacc tttaatccga caacgccaat cgcaatgcct aaaacaataa ccattaatac
     3901 aagtgttgct tctaaaaaac ttggtgttcc tttttttccc atgataatct ctcctttttt
     3961 agttgttctt atgttctaaa aaagttaaga tatcggatta ctccgccgca attcatccgc
     4021 gattcctcct ttataaaaat aaaaagacct gttttaaact aaggacgaat gactccgcgg
     4081 taccacctta attaaaaaca gatctgtttt tcactttcaa acttttattc aaatgtatgg
     4141 actttccatg taattcgtca attaggcttg atcggttcac agcgaccacc gactttctga
     4201 acaaaacacc taaccgctac tgcgtgaaaa gttgacttgt acgaagttta ccttccataa
     4261 gatcatttgt caatgaaaaa gaaaatattt tttcattttt ctgaaaatta tttttataac
     4321 tttcacacac aagtttattt tttactagaa agtagcgccc tcttgttttt ttcttgctac
     4381 tatttcttga tgttcttgct tgattctttc taatagcttt ggctctttca acagatcaag
     4441 agctgtattg gcgagtagtt ctgctgcaat cgcaatagaa gcaaggcctt tgtcactttt
     4501 agcagcagct ttgaattctt ctgtgtgtcc ggcaatatat gtctcagaga ttgctaccgt
     4561 aggctggatt gttggtatga cttggctgac atttcctaca tcagaagaac cgagacttgt
     4621 tctttgttcc gtttctattt cttcatctgg aacacctgct tcttttgcat gctggaagaa
     4681 taagtcatca aaagaaggag taacgatgac atcatcaact gcattttgga acaatccaaa
     4741 ctcaaaagtc gtgcccgtac ttatcgcagc acctcgtacg atattttcca ctttttcata
     4801 tactttatct aatgtttgcc gatttcctgc acgtaaatag aaacgtccag cagcgtaatc
     4861 tggaatgacg ttggcagcta ctcctccgtc tgtaatgatc ccatggatat tgacatcttt
     4921 tggcaattgc aagcgtagag cgttgattcc attaaacact tggatcaatg cttccaaagc
     4981 atttactcct ttttcaggtg ctgctgctgc atgggaagcg acaccgtaaa atttgatgtc
     5041 gactggatca ttcgctaaag attctgtcgt tttcccataa cgaaaagctg gatggacgca
     5101 taacgctaca tcgacatcct caaaaaaacc ttctcgaaca aagctgcctt tagctgatcc
     5161 gttctcgccc ccttcttccc ctggggtgcc atatacacgg atttctccac cagtttcatc
     5221 aatgaattgc ttcactatgc tggcggctaa tacggagtaa gtaccaaaca aattatgccc
     5281 gcatgcatga ccaatacctg gtaaagcatc gaattctgcc aaaaaggcaa ttgtgggacc
     5341 gggtttattg gaaatataac gtgcatcaaa ggctgttcgg tgtccagcta cttctttttc
     5401 tacccaaaac ctttcttttt ctaattgttt aatcaacgct gctgaggaat aaaactcata
     5461 gttacttact tcaggatgtt cgtggatatc tagagcaagt gcttgatatt ctggtaaacg
     5521 atattggatt agatccttca attggtttgt tgagattgtt gttgtcataa aaaattcctc
     5581 ctatgctagt catttttctt attttctccc gaatgtttcc catgcaggca cgcttgatcc
     5641 ttttgatgtt ttctcgatta ctttgactgt gtcttctgtt tgataagcgt ctactatttt
     5701 ttgatacgtt ttattgtttt catcttcttt tcttgcaacg atgatattca cataaggacg
     5761 tgcatggtca tccactggtt ctaagaagat ggcatcagaa gcaggattaa atccagcatc
     5821 tacagctaca ccgctattga tcactgaaat gtctacatct gacaaagcac gtgctgtttg
     5881 ggaagcatct aattcagaaa tgtctagatt ttttctattc tcggtaatat cagaaacagt
     5941 gggcgcttgt ccttttgcct tatccacttt gatcaatcca gcagtttgca ataacagaag
     6001 agctctgccg ccatttgtaa catcattagg gattgctact tttgctccgt ctttgatatc
     6061 agctacatcc ttcaaagtgt tagaataaat tcccagcggt gcattgacag tatttccgat
     6121 cgatactaaa tcagttccgt gttctttatt gtaattgtct aaaaagaatt gatgttggaa
     6181 agaattcaaa tcaatcgatc catctgctaa agccacattt ggttgattgt aatctgtaaa
     6241 tttcacgtat tccaaattaa tgttctcctt tttcaaacgg tctttcacgt tgtcccatac
     6301 atctgtatct tctccaataa tccctagttt tacgatagtt tcttttttgt cagttgtatc
     6361 tgcttttcct tggctacacc ctgccaacca aataattgct acaaatgtaa tgactacaaa
     6421 acgaataatt tttttcattt tttctcctcc actttcaatg tgtaattttt ttaatcagtt
     6481 gattactgat aaattgactt aaaaaaacta agattagaat caataatgta gccacaatcg
     6541 ttacatctgt ttggaatcga ttataccctc tcgatatagc aagattccct aatccgcctg
     6601 cacctactgc tccagccatg gtagtcagtc cgatcacgtt gatgatagtc aacgccgaga
     6661 cccgaatgat accaggcaaa ccttctaaca aatacacacg taaaatgata ccgattggac
     6721 tggttcccat cgcttctgcc gcttcgatca ccccaggatc aacttctagc agtgcgttct
     6781 cgatttgacg agcaaaaaac ggaacaactc caaaaatcaa tggcactaaa gctgctttcg
     6841 caccaatcgt cgttccaact aagaaacgag tagtcaatgc taaaagagaa agcaagataa
     6901 tgaaagggat ggaacgaatg atattgatca gcttatcaag tatttcaaat agcagacggt
     6961 tagctagtaa tccattaggg cgtgtcacta ctaacgtcac acctaagatg attccaatca
     7021 tcccgccaat gaatgctgtc caaaaagaca tatatagtgt ttgcttcgtc gcttcgacaa
     7081 attcatccgg aatcaaataa acattgggca aatatgtttt aaagaaatca gtcattttat
     7141 cttcctcctt cgatcacttt gatacgacta tctaaatcgt ttttttgtaa aatatttatt
     7201 tttacaccag atttgatcaa ataatccaat gcttttttcc gctgtttggt ttctccagct
     7261 aaagtaacga tcaaactccc taacggcgtt tcttgtaata actctacatt gccatataaa
     7321 atattcgctg ttacttgata tttgctgtac agatgagcga ttagaggttc gttcgtctga
     7381 tttccaatat aacttaattc caccagccat ttattggcga tctgatcggc aaaagcagaa
     7441 tgggcaatga tcgtttctaa tgcttggtca agatgagtag ctgttcgaat aaaatctttg
     7501 gtcaattctt cttcaggatt gctgaagatc tggatgctgc tacctttttc aacgattctt
     7561 ccatcttcca taaccgctac cttgttgcag atttctttga caacttgcat ctcatgagtg
     7621 atcaggacga ttgttaaacc taactggcga ttcaattttt ttaacaatgc aaggatctga
     7681 agggtcgttt tcggatcaag tgcactggtt gcttcatcac ataataatac cttaggttca
     7741 ttcgccaaag ctcgtgcgat tgctactcgt tgtttttgtc cccccgacag ttgtttagga
     7801 taagcagatg ctttttcttc caaaccgaca agttccagta gttcattcac tttttgacga
     7861 cgttcctgtt tcgattttcc agaatacttt aaagaaaaat caacgttgtc aaaaatagtt
     7921 cggctttcca ttagattgaa atgctgaaag atcataccga tggcctttct ttcttttcgc
     7981 aattctttgg gagagagctg actcagattc gtctgattga caatgacttc tcctgctgtt
     8041 ggtttctgca gcaaattcat cacacgaact aacgtacttt tccctgcacc tgagtaaccg
     8101 acgattccat aaacatcgcc tttttcaatc gttaaatcta cagaatctac tgcctgtatc
     8161 tctttttctt tttgtttgaa acatacagaa acatctcgca attcaatcat taaaattcct
     8221 ccttatctaa aaaaagcgtc ctcaagaaaa tgaaaatgtc attttcttga ggacgctttt
     8281 ttgcgtgtta ccacctcatg ttcaagctgt gttcacacac aactcctctt caagtacgat
     8341 catactctag caagatatcg gtcgcagccg tcatcgcctt acatctatgc tcgggatgaa
     8401 ttgctcgatg gccattttcc aatagtcgtt ccttgcttct tctcagctac cgaagctctc
     8461 tgtcaaaggt tcttctatcg tacttaccat ttcaatgcaa ataatattca aaaaaaaagt
     8521 ccttttacta acataaacta tgtcagtaaa aggacgacgt atcgcggtac cacctttttt
     8581 cggaagtttc cttccctcaa gcccaacatc tcaaaaagag agattggcgt tcgttttaac
     8641 ggtcgaacag ttccgaattt gcctacttat cgacaaatta ttctccaagg ccattttcag
     8701 cttttcttac ttgactcttc tcaccagcca gagcctctct gcaaagtttc caaacttact
     8761 ttccttttca acgaaatcga tattttgttg ttgggattaa tctacatgag gaaaactgaa
     8821 aagtcaagta cgaaattcaa attatttttt ctatatttat ttttctgttt ttttatttaa
     8881 catttcaata acagttcgaa gatcttttcc ttccgcaaga agtttcaatt tttccttttc
     8941 ttcgacggta taatttcgga caaaactgga atcaggtatc aaaacaacgc ctaatcctgc
     9001 tcgtgaagca gctgttgctc ctactaaaga atcttccact gcaaaggctg aactagcttc
     9061 taatcctgtt cgttccaaag ctgtcagata aggaatcggt gaaggcttgt tctccgacac
     9121 ttcgtctccg aatgtaaacg tgtccaagta atcagctaat ttaaagtgat ccaagatatc
     9181 tgttgctctt ttcgtaacag tggtcgtagc aatgcctagt ttcatatgac gttcttttaa
     9241 gtctgccaat atttcttttg catatggttt taagtggatg gctccgcttg tcagctgttg
     9301 ataaaaatat tcttcacgct tcgctcggac ttcctgtact ttttcagggc tacctgctgc
     9361 tttcactaaa atatcaaaac tttgtttcca gttttttccg ccccaagcgt caacgatttc
     9421 ttttgggata tggatatcaa attgctgaaa tccccaaagc cagccatcac gatacgtttt
     9481 ttctgtgtca actaacaaac catctaaatc aaatattgca cctttcatct atacattaat
     9541 cctttccaaa acaatacaca tagtttagca cgactggtcc aaaaagaaca gaagcaaaga
     9601 accagccttc tcgtttataa gagttcttgg aatcgacgga tatagatttt cttcacagct
     9661 gtcacaagcg ccagataagc gatgactgta gcaaataacc ataaccagta attgccagga
     9721 agtggcatca agcctaattc agcaccaaaa cttgtaaaag gaaggacaga accgacaata
     9781 attcctaatg tagtgataac aaacatggca aatgttgcgt tgctttggat aaatggtact
     9841 ttcggtgtac gcagtgcatg gagcactaag gtttgtgtcc atagtgattc gacaaaccat
     9901 cctgcatgga ataatgcgat gaaaatcact cgctgtgaac tatccaatgt atggaaactt
     9961 ccgcccacta cagcaggaca aataacaaaa tacatcaaca agtaagtagt aatatcaaat
    10021 atcgaacttg ttggaccaaa gtaaaccatg aattccccaa tactagatgc attccatttt
    10081 tttggctcgt ccaaatattc tttatccatc cgatcccatg gcaaggaaat gcaggaaaca
    10141 tcatagatca gattcaaaaa caaaagttgt aaaggcagca ttggtaaaaa tggcaggaac
    10201 gtacttgcaa tcagcacgga aaacatattg ccaaaattag aacttgctgt agccttgata
    10261 tatttcatga tattcccaaa agtttctcgt ccagaaagaa ggcctctttc caaaatcgtc
    10321 aaatcttttt ctaaaaggat cacgtctgca gattctttcg caatatccac agctgtatct
    10381 acagaaatac cgatatcagc cactttcatt gcaggagcgt cattgatacc atctcctaaa
    10441 aatccgacag tatgaccatt tttacgtaaa gctgtcgtca aacgtgcttt ttgctgagga
    10501 ttcaatttta cgaatacttc atggtcttca gctacttgtg ctaattcatg atcactcatt
    10561 tccgagattt tctcaccggt aaccaattca ttgatctcta gacctacttg acggcacact
    10621 gaacgtgtaa ctaattcgtt gtccccagtc agaactttta cagctacacc atgttctttc
    10681 agagctttca acgcttgttt cgttgtttct tttggtggat caaggaaagc aagataacca
    10741 atcaaaacca tgtctgactc atctttgact gaaaattctc caacgacgct tggattggtc
    10801 ttttgtgcga caccaatcac tcgtaagcca tcttcattaa gtgactgtac ttttgcaagt
    10861 acggcttctt ttcgttcttt tgttaatggt gtaacagtac cgccaagatc aataaattta
    10921 gaaatgttca gcatttcttc aatcgcgcct tttgtgatca tttgtgtttt accagctgga
    10981 tcagcaacca caacactcat acgacgacgt tcaaaatcaa aaggaatttc atccactttt
    11041 tgataattga tcttatctgt atctaaagtt tctgttgctt catcaatgat agccacatct
    11101 aacaaatttt tcagccctgt ttgatagtag ctatttagat acgcatggcg caaaacacga
    11161 tcatcttcat ttccttcaca atccatatga tattcaagaa tgattttatc ttgtgtcaat
    11221 gtccccgttt tatccgtaca taacacatcg attgcaccaa agttctggat ggcattcaaa
    11281 tttttgatca ctgttccttt tttggccatc acacttgctc ctttgaccaa attcgtcgta
    11341 acgatcattg gaagcatttc aggtgttaga ccaactgcta cagatagtcc aaaaagaaaa
    11401 gcttctagcc aatccccttt tgtaagccca ttgatgacga taactgctgg agccatcaat
    11461 gacataaatt tgatcagtag catggatgtt ttatggatgc ctaattcaaa gcttgattga
    11521 attggttttt cagatagcgt ttctgctaca tgaccaaata gtgtttcatt tccaacagaa
    11581 acaatgattc cttccgcact tccactgatg acattacttc ccataaagac aagattttcg
    11641 taacttgttt cgctttgctg atcgtcttca catactttcg catgcttttc tactggatag
    11701 ctttcccctg tcaatgctgc ttgggaaatg aataaatcct ttgcggacaa taaacgcata
    11761 tccgctggta tcatatcccc tgctgaaagc cgaacaagat ctccacagac gatttcttcc
    11821 ataggaatct ctgtgtactt tccattacgt tttacagctg ccgttacttt cacaagtgat
    11881 ttcagttttt cagccgcttg attggaacgt acggactgaa tcaacgtcat tgtcccgctg
    11941 acgataacca tagtgaagat aatggctaca ccgaaaagat ctttatctcc aggagctgct
    12001 aatacatatt ccgtgatgaa tgaaataatt cctaatgcga tcaacactaa tgtaaatggc
    12061 gtgatgtatg ctttcaatat ttctacaatg aatggtgttt ttttgccata tgaaatcgca
    12121 ttttcaccgt aattttctct tgaacgttcg atttgttctt ctgtcaatcc atttgctgat
    12181 gcatggaata gttcaaataa ttcttgtttc gtttttccag caaaagctgc atagattttt
    12241 tgtgtatctt tctttttttc catctcaatc tctcctttgt gtccaaaaga cagctgttct
    12301 cgctgctttt ggtctttagc tattcatcgg atcgatagag aaaaaactga aaggggctga
    12361 gaacagatag ataatagccc tggcctttcc tctagatcct tgtttttcga atgactgtca
    12421 tccatttgtt ctcatctcct ttactaagta attttaattc atgacttcca atcatttttc
    12481 gaatagttat ttttccaatt agaccacctc ctttttattt ttcaccgatg gggatttgcg
    12541 gcaacaaaaa aacctctcgc caaatactca gcgaaaggtt tgaaaaagca tattaaaaaa
    12601 agcttctcag atctcatcgt tgagttttga cactgtacaa cgtaaaaagc agatacctgc
    12661 ttttagctac cttatgaaaa gccttatctc gacaattcct gttctaccca ttggcgtctc
    12721 tcgacgtttt tgggcagtag cctatgtttg tataggagcc tcacctaaca aatcttattc
    12781 ggttttcctt cgttaatata acaactaaaa aagaggatgt caaatcaatt ttccatgttt
    12841 ttcatacttt ttttaaaata cacacgttat attcctgtct cacgcggttt tatttgtctc
    12901 attttccacc tcccgctata atagaaatat agtaggaaac gaggtgctgt tatggaaaga
    12961 acacttgtta ttatcaagcc agacggcgtg agacgccatt tagtcggaag catcatccaa
    13021 cgttttgaag caaagggact ggccattgct gaaatgaagt ttgaaactat gactcctgaa
    13081 ttagcaaaag aacattatca gcacttgact gagcgcagtt tttttgatga actgatcgat
    13141 tacatgactt ccggtcctgt cgtttatctt gtgctggtcg gcgaggaagt gatcgatatc
    13201 gtccgtaaga tggttggagc aacaaaagct gccgatgctg ttccaggtac gatccgagga
    13261 gactacgcgc tgccggggac tgaaaacatc attcacgctt ctgattcccg tgatgctgcg
    13321 gtaaaagaga tcgcccgctt tttcccgcca ttcgatataa acaaaccgtc tgaaaaagcg
    13381 gcgaagtgat acaaattcta aactgctggt ctagttgctg ggttcagcaa tggccagcag
    13441 ttttttctct aaggacctcc gttgattctt tcctaacata tattcgagca ctgtgaagaa
    13501 ttcttggtag tctttcgtct tttcttcccc taaagcagca gaaatcaatc tttgataata
    13561 atctgccatc aatgtttcat agatcactgt acttctttct ttatgtgata agctccgttt
    13621 catatcttca ttcacactac gtgccttttt caaccgacca ttttctatat aaaacgaagt
    13681 caggttcatt aaaaaagtaa agagatactg ctcatgattg ttcaactgtg ctaatcgtcg
    13741 cattcttttt ttgattttca aataattgtt ctcaatgaac cgatcactga atatccaagg
    13801 aaaatcagct agaatagata gttcaaattg accatagtct ggtatctgca tcaagtattc
    13861 ttcaatgatt cggcattcat aacgtaaaaa ttcaaattct gtctcagata cttctgtttt
    13921 ttcgaccatg tgaagattca aaaccaaata atacagatct tctgttttct taaaatgcct
    13981 acggttattg ctgatctctt tataaggatc aaagctgtct tcttgtaccc gatctagcat
    14041 tcgtcttttt ttctttaact ttattggttc atccagctgg tttcgcatcc attcatattc
    14101 tgcaagtgtc atgttcattc gctctaaaaa tgatctcaat gttacaaatg acattttttt
    14161 cactgaattt gtctcaatcc cgactagaga agtcttaaaa cagattcctt ccgctaattg
    14221 ggactgtgtc aacttcttgt tgactcgaag tttcttgatc aattcaccat catacataat
    14281 agttctcctt tttaatttaa atttttccac attcaataaa tagatacgtt aaaaaggaaa
    14341 aatacacgaa aaaaataaaa aaatgttttt ttcataaaaa ataccaacct tcaagcatta
    14401 gaatgttgtc taactactga aggttggttt gattgtttat tgattatttt tttgctgttc
    14461 aacgtctgtt cttgttactg gatataagtt ggttgttgtt ttattaccat tttttgaaaa
    14521 gacacttgtc gaatgttcgc ctttttgctt ttcgattgct tcattacgtt ccgcttcatt
    14581 tttatagtca tattttttcg gatcaatcgt ctcaaatccg tttggcacat aaaaccgcaa
    14641 gagattttcc tgattcagct tatctgaaag acttaacgca gtcttgactt tttcctgatc
    14701 tttggagatt tcctcatcga ttcctgctgc tttcgtatcg atgatttctc ctgtctgatt
    14761 attgtaagct tttcctccta ggacggtgta tttgggtgtc acaaagttcc catttcgaaa
    14821 agcaactact tgatcatgct gagaagataa taagtctgta ccaaaatgaa gataatcttt
    14881 atcatcgatt cccaatagat gtagtaatgt cggcaaaaca tcgatttctc caccgtattc
    14941 atgattgact gtccctttag tataaccagg catatggatc atcaatggca ctcgttgcat
    15001 ctgtgcgttg tcaaattcat cccatgtatc tggatcttta ccaagagcgc ttgctaaatc
    15061 tttattatct gtattcgaga tcccaaaatg atccccgtaa atcacaaaga ttgaattttg
    15121 gtaaatacca gattttttca aatacgtaaa aaattgttcc aatgattgat ccagataatg
    15181 tgccgttcga acataattat ctactgtgct attgccagta ttcaaagatg gaaagtcgaa
    15241 attcttgtca tccgtataat aaggcgtgtg gttggttacg gaaagaaatt tcgtgtaaaa
    15301 cggctgttgt agatgctcaa gatattgggc agattctctg aataaatctt tatctaatat
    15361 cccataacct aacgtttcgt cggattcatc aaaataagat cgatcaaaga aattgtcata
    15421 acctaagttt ttatatacat gatctctatt ccaaaaacta gctacattcc catggaaaac
    15481 agcgcttgta tagccttgct tttgtccaag gatcgctggt gcggcttgaa agacattgtc
    15541 tgacccaagt tctgtgaata atgagccttg aggtaaacca aatgtgccag tttccaacat
    15601 attttcagca tcacttgtct ttccctgtcc tacttcatga aagaaattgt caaagctgat
    15661 cgttgcttga ttctggaaaa tactatttaa aaacggtgtg acttcttgtc cgtctacctt
    15721 catattaatc aaaaactgct ggaaactttc taaatggaga acgatcacat ttttcccttt
    15781 agcgatccca aatgtttcgg gatttggctc tgcataatgt ttctttgtat aatctaaaac
    15841 ttcatcaatc ccattactgc ttgcatgcgc gcgaacactg ctagtcattc ctgttttgat
    15901 tccgtcataa atagtatacg catcgattcc tagatatttg acaatatatg aacggtcaaa
    15961 tgttcgctgc agcaattgtg gacggttggc ttcgctcagc gctagatttc ctgaaaaaat
    16021 aagccctgaa agacaggtaa cagcgatagc catcggtttg ccgacagggt tgcttttgat
    16081 aggtattttc ttgaccttca accaaaccag tagcccaatg aacacagcga tatccagcca
    16141 gtagatgaca tcatggggct tcatcaaaga aaaggagctt cctgacaatc cttgcgacac
    16201 tttcgaaaag cctaatacag atttgactgt aatgaaatct gtgaattccc gataaaaaat
    16261 aatattcaag tacaacaaaa gcgtatttaa aatatcaatg atcaaaagaa tagctaacgc
    16321 tggctttggc tttttaatat acaaagaaag gccaaaaaac aataaggtag tcgcaattgg
    16381 gttgatccac aagataaagt actggatcgt accttccaca cctaatgaaa aatctgcata
    16441 gtaggcaatg atcgtcttca gccagaaaaa gaaaacagct gtcaaaacga ttgctaaacg
    16501 attttggcac aattttttaa gttgtgtcac gtatatcact tctctctatt cacatttttt
    16561 cttattttgc tcctgaaaaa tgaaaatttc ctaaaaaagt tgttatctta agattttttt
    16621 attctttcta aagattattc cgtccacttt tcacagcata aaaccgctgc gatgtaagcg
    16681 attaaactaa tgaagagata aaagtcttgt ggtgaccgct tcactccacg gtattcaaaa
    16741 gccagtttct cggtattcgt acaaaaaaag aggctgtgac aaaattcttg tcgcagctcc
    16801 ttatttcttg atgcaggaca gctttttcac aacttcttcc ttaaacggtg ttctcctgcc
    16861 aactcctcgg ccacaagtca caatatttat aaaacatgag aagctgtttt ttgaaattgt
    16921 tccttgtggc tcagagttaa acggcaggct caagacctct tgatacacgg tgttcaatca
    16981 gctgaccctc ggtattagat tatgtcagga cgctaatttt acaacctctt ggtaaacggt
    17041 gttcaaaagc ttgcatctgc ggtaataagc ccaaccaaac gaaaaatata aggagctatt
    17101 ttttgaaatt gctccttgtg gctcagagtt aaacggcagg ctcaagacct cttgatacac
    17161 ggtgttcaat cagctgacct tcggtattag ctcaaaaaac ggcaaaatat gaggaactat
    17221 tttgccgttt gtttctctaa tactcaggtc aaaacgctga tttcacaacc tctgtttttc
    17281 attgtccata ggattgatat tgtccttgtg atgactcatt cgtaataatt gaggcttgat
    17341 tttcttcact tcccgttatc gtttgtccac tgccagaatc tgaaggactt gttcctgtcg
    17401 actcgttttt ttgagaagag acagttgttt tcttgacttg ttcatttgtc tttttccatt
    17461 ccgctaaacg atcggcgacc acttttttgt ctactttttc agaataagcg gtgatcactt
    17521 ttccattttt caaacgggct actttgtcgc caacatgagt caaaagcaaa acggtcaaat
    17581 gcttgtcttt aaattgatat tgtctgagag aaatcgcact aagtacgtca tcgatattaa
    17641 taaattgatt ttcttctttt ccttttggca aataaatgtc caattcgcct ttttcgtaat
    17701 tggcagttat tttatactcc gcccaccaat aagttgagaa ttcttttttg aaattatcta
    17761 ctgattcttt gcttgctacg attttttctg tttctttctg agcaagatct gctgtcattt
    17821 ttcctgaaaa tgctgcggat aaaataagca gtaagaaaaa accgaataac caaaagagaa
    17881 gaaacggtct ttttttcctc atgctttcct ccactcctat ttaattttga ctattctatt
    17941 atatacaaaa aatgaaatag aaagacaaaa aagttgaaaa agatcgtaaa taattgaact
    18001 tctttttcac aaaatggtaa gaatggagaa tttcacgcat ttgctctcaa ctattctttc
    18061 ttaagcctca aatccgtttt tatctgatac gtctttgaac caatgacccg attttttgat
    18121 tgttcttttt ccatcttgtg ctaagtctac tgaaataaag ccatatcgat tcttatatgc
    18181 attggtccac gaccagttat ccatacatgt ccacatatga tagcctaaac aattggcacc
    18241 ttcttgaatg gcttgatgga catatttcag atgagattgg acaaattcga tccgataatc
    18301 atcgtggatc atgccatctt ctttgataaa tcgtgcttcg ttttctacac ccataccgtt
    18361 ttcagaaata aagcagtcga tatttccata atgatctcgt acattgatca aaatatcata
    18421 gattccttgt tcatagatct cccatccgcg ataaggattc attttacgac caggcatttc
    18481 ataattgtcg aaataatcct caggcattgg accgttttta gtatcgattg gtgtttcttt
    18541 tgcttttacc cggcgtggct ggtaataatt gatacctaaa agatctactg tattttcttt
    18601 gataaccgtc aaatcctctg catggatcac aggcatgaga tcaagttctt ttactatctc
    18661 aatcaattca cttggaaact cgccttttac agctggatca aggaatgaac gattgaagaa
    18721 cgcatctgct atttgcgctg ctttaacatc ttcagggttt gattcgtctc ttggatagct
    18781 tggtgtcaga ttcaagatga taccaataac accaccttgc tccatttcat ggtaagattt
    18841 gatggctaac gctgaagcca acgcttcatg atagccaact tggatcgctt ttttcatatc
    18901 tgactcttct ggataatgcc atcgatataa ataacctgct tcgactggaa cgattggttc
    18961 attatgagta aaccattttt ttactttcga accaaacaat tcaaaacaac ttttggcata
    19021 tttttcatag gcttcaaccg tttctcggtt caaccatccg cctttttctt gcagatacat
    19081 cggcatatcg aaatgataca gattcacaaa gggttcgata ccgttttcaa tcaactcatc
    19141 aaaataacga tgatagaaac gaacggcttc ttcgttgatt gttccagatt catcaggtat
    19201 caaacggctc cattggatag atgttcgaaa tgaattatgc ccagtctgtt tcatcaactg
    19261 tacatcctct tgatacttcg tataaacttg cgaggttttt tcaggtccta cttgatcaaa
    19321 gaacttttgc ggttcttttt tgtaccaata atcaaaaatg ttctctcctt ttccatcgcc
    19381 tgaaatcctt ccttctgttt gtgggccact tgctgcagaa ccccaccaaa aatttgctgg
    19441 aaattgatat tttttcatca aagcacctct ttttcttttt tagttcgttt tagttgattc
    19501 catgtatgat attttccatc acaatcactt tttcattttc ttcctcttct tttttgattc
    19561 gttttaacag ctgttctgct gctcgttccc cgattttatc tgttggtggc gtgatcgtga
    19621 ttttcggaag gatactcaga tcgtttttat ctaaataatc atagtgactg aacgcaatat
    19681 ccttcccgat tctgacacct tcttgattga aacattcgat ggcaccaatc gacatattgt
    19741 aattgctgac aaaaatagca gttgcccctt tttctaataa tgcttttgcc ccgtaatagc
    19801 cgctttttct agaatagtct cctgtaaaga cctctaattg gatcgatgga tcattttgga
    19861 ccgcttcttt ggctcctgct aaacgttctc ttgctacgta gtctgtttga gtggcagcaa
    19921 taaatccgat ttttttatgt ccttgttcac catgatgagc gatcactttt gctacacttt
    19981 ctcgatcatt cactaatatt gtatcaatac ctgctggtcc ttctggacaa ttcaatgcga
    20041 taactggaat actcattttt gtgagcattt caaatccaga ccactcttct tcggataaga
    20101 agacaatcag cccatcgatc acatgcttca tcaggtattc aattttttgt tcaatttttt
    20161 ctggctgatc ggcaaacccg cttaataata agctataccc attttcttca gctactcttt
    20221 cgatccctga gacaacttcc gacccaaaac ggctggaaat cccgtttatc aaaagtccaa
    20281 tagagaagct tcgattattc ttcaaccctt tagcaatgat gttttcttta tagtccaacg
    20341 ctgaaatcgc ttctgctatt tttttcatgt tcttttcctt cagttgctga ccattcaagt
    20401 aacgggaaac tgttcccact gaaacaccag ccatcttagc cacatcacgg atcgatgcca
    20461 tacattctca ctcctgccag ttacatttga tttctctttc ttgttgttcg attatgatga
    20521 ccgcattctt tgcatagtgt tgcttgtcat caatatccat ataactaaag tcttcagtag
    20581 agcaacttcc tctcactatt aattatactt aaacaagtat ttgaaccggt tcatttttaa
    20641 tatagcattt ttttaaaaga ttgcaacact tttttaaaac gctttctgaa agtggcggat
    20701 tttttgcctt tttaaaattt tattctaaaa tttactccat ttgtgggtgt tttgtgcgtt
    20761 tttctcttcc atccgtttga agttttacat tccaatggta taatttcttt atcctatcaa
    20821 atgggggaag tattttgaag aaattaatcg tactatttat tttgtctgcg ggacttttga
    20881 cattgactgg ctgtgatttg tttggcggct ctgaccaatc ctcggacgaa acaaccgatt
    20941 cttctgtctt aaaagcggaa aaagcagata ccaccaacag tgtatatacg ctaaaagtac
    21001 gtaaagatat ggatttatcc gcgggacagt tgacatttac agataaaaaa atggaatgga
    21061 cacgcacgta tcagacacaa ggaactgatt cttctgaatc atctgaagaa aaaacagtgc
    21121 tgacagatat caagatcact accaaagatg acgaatatat tatttcagga aaagaaaata
    21181 aaaaagaaac aacagtcata tttacaaaaa tcggtaatta ccgtttgaag gatgaggatg
    21241 gcaacatcta cagtctatag tgccgtctgt tggatcttct tttgtttctc cccttctttt
    21301 ctgctatagt aaagaagcaa gatgattgta aaggagacga aatggatgat cgatagtcct
    21361 gattattgta catgtaataa caacaaaaat atccatacag aatttaatga ccaaggaagc
    21421 ttgagcatat gcgacaactg tcacaaacta gtcaaagatt catttaaaac atttgaatct
    21481 tatcctgttc aaaattatgt aaaaagtaga agaagataaa caaatccaag caaaactcac
    21541 tatggctgat ttttatgaac ttcaaactca gcttcttcct ttgatcaagc ttcatcagta
    21601 aaacaaacag tggatcattt cagtttacaa atcaaagagt aaagatttat ttatttcaaa
    21661 tatttgaata taaaataacc aaacgataga aaggcttatt ctacatcacg tagtaatttt
    21721 tctttcccgt cgtttggttt tttattttta gcctaattct tgaccttttg catgctggtt
    21781 atccgtaaaa tattttccag caggctttcc ttccaattca gctaattttt cttggatctg
    21841 acggatcacc ttttttgcat cttctggatt ttctacaaaa tcgaatttat ccccatccac
    21901 ttgtatttta ggacatacat caaaatcttc ataccattga ttatagcggg tgttcaacgt
    21961 ttcataatag gtatataacg tctcatcgct ttctagctgt tcatagtcac gcccacgttt
    22021 tttgatacgt tctagcatcg tgtccaaaga aactttgata tggaccatca aatcaggccg
    22081 tttttttgga gcaacatcat ctaactcgtt tagcatcgta tctaataagc tatcgtactg
    22141 ctgtacttcg atatccgtta cccgacctaa atcagcgttt agatggaaca acaggctatc
    22201 ttcatagatg gatcggtcta gcacattgtc atcgttcact aaagcatttt tcattgctaa
    22261 aaatcgcttg ttcaaaaaga agatttgcaa taaaaaagcg tactgctcag gatttgaata
    22321 aaagagcggc aatacttcgt tatcttcgac attttcataa aatggtttag aatcaatctc
    22381 ttttgcaagc atatccgtca aactgctctt acctgcacca atcgttcctg aaatcaaaat
    22441 cactgacata caacccttcc tcttctataa gtactcgcct acgtaagttt caacaggcaa
    22501 tgtttcaaaa tcatattcac gtacagcttg gtctgatttt aaatacgtat ggagactttg
    22561 tgtaatcatc aagttcgtag gtaccgtctc ttcttgtaca atgatcatcg gttttttcaa
    22621 catagttgcc acacctaatt cgtaagccgt tcctggatcg attgtttgat gctcaaagtc
    22681 aaggatagca acaacaaatt ctgcatttgt cagttcttcc atatcttttt cgtatacttc
    22741 ctgcgcccat ccagcgctga atagttcata attgctttct tggtgatgac gtggagagta
    22801 gaaacttgtg actgttttgt tttcctccaa cgctttttcg atacgactta ctcgatcgat
    22861 ttgctcctct gaaaaaaatg gtcctgctaa atatatttga ctcattattt tgcctccttc
    22921 aataataact gatttttaat agatactgct cgtaattcat tgaccagttc caatggattg
    22981 ttggaaaaga ttacttgatc caaccatttt ttatccataa aatcctcttt tgcaaaagtt
    23041 tctaataatt gttgcaagcc gctgtaataa ccgccaatat tcaatattcc gattggcttg
    23101 tcgggcgtca gaccgattgc tatccaagaa agaagttgtg agaattcctc caatgtacct
    23161 agacctccag ggaaaacgag gacagcatct cccttttcaa ataataatac ctttctttca
    23221 tcgatcgttt ctgtaggaat aaatgtagta acatcttttc caggcaattc agtttcaaaa
    23281 agcccattcg gatagatacc tgtgactttt ccgttatttt ccagtactgt tttactaatc
    23341 actcccataa tcccggagta tgaaccaccg taaaccagtt cgatttcttc ttgtgccatg
    23401 tattttccta acgtttgcgc aataaatttg taactttctt tattaccaaa acgggaaccg
    23461 caaaaaacag taagtttcat aaaaaaacac tccctaactc aaaagtctat cttcattcta
    23521 cacgtgtttt tttaaaataa aagactagat tttgtagttt tttagtggta tataggatag
    23581 acgccactat atatagtatt tagaaaaaaa tcatttttca gccattttat agataaaaca
    23641 aaaataaata acgtgttttc atcgatatga aatgacttac ttatagaaga tactgggatt
    23701 tcgtcctata tgccaataac gtgtattatt ttaaacaaca aatacttgtt tcttttatta
    23761 acgaaaaaat cattttgttc tcgtgttatg tttcactgat aaatgatgtt tctctaaata
    23821 aaaaagccga cgaactaaac gatcaaaatt tgatcatttt tgttcatcag cttctcctaa
    23881 aaatcttttt gttaacgata aatagctgga tttgtaaaaa tatcacttga atcgtcactg
    23941 ctggaagaaa attcagtgat aaccgcacct gttgcgcctg cctggaacta gtgtttgata
    24001 ttgggctcga acgtgtactg atctctagca tgaagaataa tttctttttt tactgtataa
    24061 taactttctt tcctttttgg aatagtacag gaaagttttt ttgtttcctt tccttcgaca
    24121 taaggtatac cagacccttt cgacaacgaa aggttctcat ttttccttca tcgtcatttc
    24181 aaggagggtg ccgatgctct ggacagtttc gatcgctcct aaaccaaaat ctgtatattc
    24241 gattctttct aactctgatt ctttcatacc attcctgtct caaggtacat ctattgtact
    24301 tttttcttgt aatccattct gcctctccta actaattgtc aaatcatccc aagatatgtc
    24361 ttcttcctct ttttcttctt ggatgatttc tgcattcgga tctactggtt ttttcaataa
    24421 taaaatggtt attcctgtga caaaagaacc agctaacaat gcaccaatga atgcccatgg
    24481 tctggtcatc gtagcgactg caaacattcc cgatgccgga atacggctat ctgcgcccca
    24541 aaacatgctt aatccgccac ctactgtccc accgactccc gttgctatga cattgcgtgc
    24601 caagtcgttc aatacgatag ggaaacatcc ctctgtgatc tgacagatcc ccataggaaa
    24661 agcggtcttc aatgtatcga tttcttgacg attgagtata tttttacgaa tgattttccc
    24721 taagaaataa gcgatcgtca agccgaatgg ggttaccatc gaagctaaaa tcaatacagt
    24781 gattggttca tagattcctt ctgaaaatcg tgccacaccc ccttatccag aataaatggt
    24841 aatccagaaa cagccgtgta tctgcggtaa taagcctaac caaacgaaaa atatgagaag
    24901 ctatttttgt ttggctgttc ttattacttg atgcagggca gctttttcac aacctctttt
    24961 tttatttatg tttcataatc aatatggtaa ggatgcagct ccgtatggta gaccgcctcc
    25021 gaatattcaa tcatttcccc aatttgcgta gacgatttcc gtatccgttt gatgccgatc
    25081 tgtgcgtctg ttttcagaat tccttgttct tcttctgtta aaaatactgc cgagaaatca
    25141 tcagaaaatg agtcaatagt atatcctttt ttcgtcagca aacgatacaa agattctttg
    25201 ccaaattctt ctctgctgaa ttgcatcatt tcttgtggaa gataatgaac aaaataaata
    25261 taaggctgat tgttcaaata atataagcgc ttaaaacaaa cagcttgctc accgaaaaag
    25321 gaaaacaaag gatcttcctt ctttatatgg accaattgca aatccagcgt ttctttccgg
    25381 acttcatatc gggagttctc caagatttgc gtaaagcttg ccgctttgga taatcgattg
    25441 taaggacgat tgcttagaac cgtcgtccca cgaccacttt tctttgcgac atattcatct
    25501 gatgccagca gttcgattgc ctttcggaca gtgattttgc tgacttgaaa cagttcttct
    25561 aattcacttt ctgtcggcaa catcgaaccg actggatatt ttcctgagaa aatatcttct
    25621 ttaattttat ctgcgacttc caagtatagt acacgtgtcc ttttcataac gtcacccttt
    25681 gctttactat tactaaaaga atagcacata aaaaataaaa aaagaacaca aatcacatgt
    25741 gagaagtgtg ttctttttca ttcagctgct ttaattacaa gtttacgcca tttgaggcaa
    25801 ttacttcttt ataccaatca aaagattttt tctttgatcg attcagtgtc ccatttcctt
    25861 catcgtctag atccacatag ataaagccgt aacgtttact catttctcct gttgatgcac
    25921 tgacaagatc gatacatccc caaggcgtat agcccatcaa atctacaccg tctgctactg
    25981 cattagccat cgcttcgata tgacgacgta aataatcgat ccgataatca tcaataatcg
    26041 tgccatcctc ttccatatga tcaatggctc caagaccgtt ttcaacaatg aataatggtt
    26101 tctggtaacg attgtataat tcattcaatg cgattctcag cccttctgga tcgatctgcc
    26161 agccccattc acttgcctca agaaacggat tttttactcc tcccagcaag ttcccttctg
    26221 aagttgctgc ttgtggatca gtctcattga ttgccgtaga catataataa ctaaatccga
    26281 tgtagtccac tggatattct tttagcaact ggaagtcttt ttccgtttgc tctaattttt
    26341 ccggatcgac tccatatttt ttatgggtac gcgctgtgta tgcagggtat tctccacgta
    26401 cttggacatc cgtgcagaaa aaattgaatt cttggttttg gatcattgtt gctgcctgat
    26461 tgactggatt ggcatcgatg ctgtaagttg ttgcatagat aatcatgcag ccgatttgga
    26521 tatccgaacg caattcgtgg ccgattttta cggctttgct acttgcaacg aattgattat
    26581 gccatgcttg gaaaatattt tggtactctc ctgctccatt gctttttact aatccttgac
    26641 ttaaagctgg aaagtgaaag gccgaattga tttcattgaa agtcatccaa tatttgactt
    26701 tactgctgta tctctctaat actgtctgag caaatcgttc atagaagtcg atcagttttc
    26761 gatttttcca gccaccgtat tcttttgcca aatgaagagg catttcgtaa tgagaaatcg
    26821 tgatcacagg ttcaatatca tattttaagc actcatcaat cagctgatca taaaattcta
    26881 atcccgcttc gttaggagta ccttcgtctc catttggaaa aattcgtgtc caggcaatcg
    26941 aaaaacgata acatttgaat cccatttccg caaacaaggc aagatcttct ttgaaacgat
    27001 cgtaatgatc aattcctcga tgattcgggt aaatatattt ttcttgatca atcgtccagt
    27061 caaattcttc actgccgata atcgcaaagc gctgcttacc tccaggcata gcatctgcaa
    27121 cggatagccc ttttccgtct cgatcataag ccccttctaa ttgattggca gcagttgctc
    27181 caccccataa aaatttttct gaaaaacgtg attgcatcct gatttcctcc ttattttaca
    27241 attgccagaa catcttcgtt tgcaataatc tctttttggt ctaattcaag tatatcggca
    27301 aatgcatcag tattcgtaat gacaactgga gtgattacgc tatagccagc tgctctaatt
    27361 gcttcgatgt caaaacgaat caataaatct cctgctttga cgagatcccc ttgtttgact
    27421 aagatctcaa agccattccc atttaattct actgtatcca tcccgatatg aatcaaaatc
    27481 tccgctccgt cagtcgttgt gatccctaca gcatgtccag ttggaaaaat agtcgtgatc
    27541 tctccgtctg caggtgcaac tagttctcct acttctggat caatagcgat accttttccc
    27601 atcacgccag aagaaaaaac ttggtctggt acttcactca atggcagtac tttacccgtt
    27661 aaaggacttt ttaaggtatg ccgtgctgaa gtaatcggtt ctcctgcatt cgcatgtttg
    27721 ttttctaatt gattgtcttg tgtttgttcg tcaaatccta aaatcaatgt acctacgaat
    27781 gcaagaacaa aagcaattcc tgtagctatt actgctactg tcacatttga ctctacacca
    27841 tccaccgtat taatgaaagt cggaatcgtc aataagctga ccaaactgct ggagaaagct
    27901 tttactccgg aaaatccgat aatagctcca ccaatacctc cagaaataca agcggcaatg
    27961 aatggtttct tcaaaggtaa tgtcacacca tacacagttg gttcagtgat tccaaataac
    28021 gaagtcactg tagaagaaat ccctaatgct cgaagtttcg tatcttttgt tcgcaatgct
    28081 acagctaaag cagccccacc ttgtgccaag atggctggaa gaagcattgg catcaataca
    28141 tcaaacccat attgttcgat attcaaaaac atgatcggta cgaatcccca atgcatgccg
    28201 aacatcacga atacttgcca taaacttccc atgattagac ctgctacgat tggactaaat
    28261 ccataaatcg agttgaagag accgcctaaa gcattaccgg caaccgtccc gattggtcct
    28321 aaagcaagaa atgttaatgg aaccatcact actaaaacga caagcggaac taaaatcatt
    28381 tgcagaaatt gcggaatcac tttttttacg aatggctcta atttactttg aacccatacg
    28441 gctagaatga ttggtatgac agaagaagta taaccagatg gtgaaagaat cactgggatc
    28501 ccaaagaaac tgatagcttc tcccgcacca gcaactgctg tgatagctgg atacacaagt
    28561 gccatagcaa ttgctactgc taaaaactgg ttggctttga actttttagc tgctgtaaaa
    28621 gcaagcatga caggtaagaa ggtaaagaca ccatctgctg cagcaaacaa tatttgataa
    28681 gtaccgctat cagctgtcag ccagcccatc accgttgcca atgataagaa tcctttcaat
    28741 accccggcgg ctgccatcgc ccctagaaaa ggtgtaaata tactagagat aatatcgatc
    28801 agacgattca aaatattttt ggactcttct tttccatcct ccgaaactgc aagaccttcc
    28861 tcatccacga tcgattgata aacatctgct acattactgc caatcactac ttgatactga
    28921 ccgccacttt gtacgacttg gatcacgtcc gggtcttctt ttaacttttg cgtatctgct
    28981 aaagattcat cttttaatct gaatcgcaac cgcgtagcac aatgtactaa acttttgaca
    29041 ttcttttgtc ctcctaccgc ttcccataca cgacgaccaa ctgcttgatt atccattgtt
    29101 ttttccttct ttctttttta tttaaaaaat aaaaacccag attgaaaaaa acagtcacaa
    29161 acattcgtga acctattttt tcaatccagg ttttgcctgc catacagtaa caatccttat
    29221 gattggatgc tttttttctc acttactact ctttgaatat gaatcgttaa ataaatctgc
    29281 tctgcgatcc ccatttcctg tttttgcgtt tgtcgaagat actcattgat ccgttcgaca
    29341 caatgaaacg cttttggata ctttccttga actaatgcgt agagaaattc atcttgctcg
    29401 tcagatcctt cccctttgag ataacgctgg gcaaaaaact gcagatgagt aatgatacgc
    29461 tgataattca aagattcttc atcgaacacg atgccgaaga atttactgat gatactcagt
    29521 atatctctta ccattgtggt agcggtcatc gtcacttgca tgtcttcgtt tccttgttgg
    29581 ctattcacaa aatgaaaggc aataaaaccg gcttcatcct cagaaagttc cacacccgtc
    29641 ttttgtttca cgaacaaaag agcctctttc gctgcttgat attctttcgg ataaaatttt
    29701 tttgtttcaa ataataatgg attaggcagt tggatatttt cttttgctcg tgtgatcgca
    29761 taatgaagat gatcggtcaa tgtcagataa atattaggcg aaaattcaac ttttagttta
    29821 tcttcagcca gttcgactac ttgtttgacc cattcgatct cctctgccgg aatatcagcc
    29881 atcagctgct ggaattggtt tttagcaaaa gaatctctta aaacaaattc tttttggacc
    29941 gcttctggcg aaatctcgtc cccaatcttt ttttgaaaag ctagtccttt tcccatacaa
    30001 acgacttctt ccccgaatcc atttttcgaa atgacgacat tgttattcaa aattttatca
    30061 attttcattt tgcttcgccc tctcaagaaa aataaaaaaa cctagaattc gcctactgtt
    30121 tcttagctga attctggttt tgcctgccgt acagtaacaa tccatttctt attcaaaatc
    30181 atcataccat cgaattttta tttatgcaag ccttttcata taaaaaataa aaaaactgga
    30241 acacaagtct atctagaaaa caaccaaatc agagatgcac ctctttgcgt ttctcttttt
    30301 ttcagcaaat tggtttttcc ttatcgattc atatcctttg gctgttttta atctgtaacg
    30361 acttatgtcc cagtatccta aaatgttttt gtctctagat tgaaagcaga tctcatatca
    30421 tctgtcgcat cttttatcga tgtaacactt tccagttctc cttgtacaac tagtcgcgtg
    30481 acggcgtcca tgtcgccaca agtaattagt gtgacaattt cttttccctc gacttcattc
    30541 agtaattggg tatctgtagg agcaactttt tctttaaaaa atgttttgta tgtatacaca
    30601 ttttctaaat ctgtcaaata gatcttggca cccatctcta aattttctag cggtgtaaac
    30661 agcaattcag ggttcgttgc acgatggctt gctaaggcat aatttccttt tcccatttct
    30721 tgatctggag ataatgttcc tgctccgtaa agtagtgacg tattatccaa gcctttgaaa
    30781 accggtaaat tgattgaaac tgaagggact gcgatactag caatcactgg tagatctgtt
    30841 cctctcattt gcgacctcat gaccccttct gtcgtcattg gttctaccgc atcaaagtca
    30901 aaactgacat ctttatcgtt attctttttc agatcttctt ttgttacatt cgctatagca
    30961 tatttatctc ctgtctctct gacaaaataa tccttgatct gttcattgaa aatcaaagct
    31021 agtcctacta ataacaagag gaacaagagg atattgacta gccatctttt tgcttttcct
    31081 ttttttttca ttttctctcc ctccagactc attttactgt ttttcttttg ctctttccaa
    31141 cagccgaatg acacatttct acaactctgt gtattttttt cgtacacctg cgcttttttc
    31201 tacaggatat ttcaaattat ttttgatcaa tttttcttca atgatctcat ctagatccag
    31261 gtgaaggttg tctgccatca tgtatgaata gatcaataca tctgccagtt cttctttgat
    31321 tcgttctaat tgtgtttctt ttacttcttc cggcgttttc cattgaaaaa gttctaacaa
    31381 ttcagatgct tccaaagaaa tagagatagc caaatctttt tcgttatgaa attgtcgcca
    31441 attacgttca tctctaaact ggttgacttt ttccatacta ttcatttgct tgccttcttc
    31501 caatcacttc ttacttgatt aatcatacca tttttttaca taaaaaatag atgatgcttt
    31561 taaaaaaact cctgttttct tttatttaaa ataaatgtca tagaaaatca ataatttagg
    31621 tagccaccat gtgtatgcag tagcgtgtct tcttcccttg aggctttttg tttttcgata
    31681 cgttcttctt cccaaacaga caacgctact agaatctctc ttaatgattt tccttcttcg
    31741 gtgagcgagt actctacttt aggcgggact tggttatagg cttttcgatg gatactttca
    31801 tcttgttcta actctcttaa ctgctgggtc agcatttttt ttgtgatcgt agggatttgc
    31861 ttgcttctcc acgcctaaaa taagcgatat tgctcttccc tttatctggt gtaagcaaag
    31921 cagttagcat tttgacgatc gtgggttccg cttttcactt cttatctact tagtatcatg
    31981 aagtatactt tcgtactaat actaagtagc ggaagtgtca actactttgt ttaactacat
    32041 agcaaaagaa acagaagggt gacaacggtc atcacgcttc tgtttctttt gaatatgctg
    32101 tgttgttgtc tctatctccg tgtagacttt cctcaaactt atcctttgac agtaagtcag
    32161 taggctgatt tgctctttct agatgccaga tacatttcta caaaaaaata gtgattctgt
    32221 tttgaaaatt cgatttttag ttctgcattt tcgtaaacat ccaacatttt tttcgcactg
    32281 tatagaccta acccgccatt ttttttagag gtttttcctc ttttgaccat ctccgatagc
    32341 gtcaaattcg ttggatttgc cttgttcgct atactaaaac gtgatccctc tttttcttcc
    32401 agcagattga tcgtaatcgg actctgatcg gctacacgat gatcgaatgc gttagaaata
    32461 aaaatagata aacagcgaat aaaaacaacc agatcaatcg ggattgtttt cacttcgaca
    32521 ggaataacta cttggatcgg gattttctcc gattctgctt tttctagaaa ttttaaaaag
    32581 acacccctga cagctgggga tacaatattt gttagctgtt gtatttgcgg tttttcaaaa
    32641 atagctgcag aatgatcttc taatatttct aaaaattcca acgtttcttt tttattttcc
    32701 tgaagagtaa tttttaatga aaacagtaga cttttataat catgtttgaa ttcctctaga
    32761 tgatggtaat attcttcatt tatttgatac agttgaagcg attcctgatg ttgtctttct
    32821 tttacttgga aactgatcaa cataatggaa aaaaacaaag aaaaaaaact gatgactatc
    32881 gacaaaagag atagaagcag ataattagat gagcggaagt gaacacttcc caataccaag
    32941 taaatcacgc cccagcttaa taaaatacaa atacctccaa aatagtgttc agttggataa
    33001 gtaaaaagca agttgagaaa tctcgtctgt ttgtctatac tttttactaa tagatagaaa
    33061 ataaatgcga taagtagtgc aaaaaaactt gctgttccaa gatgtctctt tcctaaataa
    33121 tccatcagat caaaaaccag aaaaaagctg agtccagtga tagcaaaaaa aagattactg
    33181 atcaaacagc tgataaacag gtttttcgta gtaaaataaa aaagaaacat caataataag
    33241 ccaattaggt aaggaaagct cactttaggg ataggaagta aaagtgtcac caccatcaaa
    33301 gctatacaac caaagctgtt ttttactagc agttgtttcg aaaagaataa atagatacct
    33361 aaatctaaaa tcaaagtaaa ggtcaaataa agtgtcactg ttgcgaccat cttattcctc
    33421 cattgttttg tttcaaaatg tacacatatt tttttaatag gagcctgcat atgaaaaagt
    33481 attttatcat agaagataac cagtttcaca gcgaatggat catcagagaa ttggtcaatc
    33541 atcatatcga gaatatcgtg cagctcactt ctatctctca aatcaatcag ttgatccagt
    33601 tgggcactat tgataatcac gatgttttct ttatcgatat cgacttgaag caatcactca
    33661 caggtattga tgtcgccgaa caaatacgta aaaaaaatgc acatagtaat attgtttttt
    33721 tcaccgctta tacgaatttt gcagtagaga tcatcaatcg gaaaatcctt ccgattggat
    33781 atatcagaaa agacaggaat ttatctgaac aaattcgtca agtgctagaa cagatcaatt
    33841 ggaaagaaca gcagatcgta aatgtcgata aaatctttat tgatcaaaaa ggtggaagtc
//
LOCUS       DAXLPC010000023        33338 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.023, whole genome shotgun sequence.
ACCESSION   DAXLPC010000023 DAXLPC010000000
VERSION     DAXLPC010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.023"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(7..123)
                     /locus_tag="ACF3UE_001047"
     CDS             complement(7..123)
                     /locus_tag="ACF3UE_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFD3634497.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(196..1152)
                     /locus_tag="ACF3UE_001048"
     CDS             complement(196..1152)
                     /locus_tag="ACF3UE_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD3634498.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            1323..1691
                     /locus_tag="ACF3UE_001049"
     CDS             1323..1691
                     /locus_tag="ACF3UE_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFD3634499.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            1861..2292
                     /gene="mraZ"
                     /locus_tag="ACF3UE_001050"
     CDS             1861..2292
                     /gene="mraZ"
                     /locus_tag="ACF3UE_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFD3634500.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            2313..3272
                     /gene="rsmH"
                     /locus_tag="ACF3UE_001051"
     CDS             2313..3272
                     /gene="rsmH"
                     /locus_tag="ACF3UE_001051"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFD3634501.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            3277..3678
                     /gene="ftsL"
                     /locus_tag="ACF3UE_001052"
     CDS             3277..3678
                     /gene="ftsL"
                     /locus_tag="ACF3UE_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFD3634502.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRRVK"
     gene            3679..5871
                     /locus_tag="ACF3UE_001053"
     CDS             3679..5871
                     /locus_tag="ACF3UE_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFD3634503.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            5897..6859
                     /gene="mraY"
                     /locus_tag="ACF3UE_001054"
     CDS             5897..6859
                     /gene="mraY"
                     /locus_tag="ACF3UE_001054"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFD3634504.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            6873..8234
                     /gene="murD"
                     /locus_tag="ACF3UE_001055"
     CDS             6873..8234
                     /gene="murD"
                     /locus_tag="ACF3UE_001055"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFD3634505.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            8260..9348
                     /gene="murG"
                     /locus_tag="ACF3UE_001056"
     CDS             8260..9348
                     /gene="murG"
                     /locus_tag="ACF3UE_001056"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFD3634506.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            9363..10583
                     /locus_tag="ACF3UE_001057"
     CDS             9363..10583
                     /locus_tag="ACF3UE_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFD3634507.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            10739..12064
                     /gene="ftsA"
                     /locus_tag="ACF3UE_001058"
     CDS             10739..12064
                     /gene="ftsA"
                     /locus_tag="ACF3UE_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFD3634508.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            12087..13328
                     /gene="ftsZ"
                     /locus_tag="ACF3UE_001059"
     CDS             12087..13328
                     /gene="ftsZ"
                     /locus_tag="ACF3UE_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFD3634509.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            13345..14022
                     /locus_tag="ACF3UE_001060"
     CDS             13345..14022
                     /locus_tag="ACF3UE_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFD3634510.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            14036..14635
                     /locus_tag="ACF3UE_001061"
     CDS             14036..14635
                     /locus_tag="ACF3UE_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFD3634511.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            14716..14937
                     /locus_tag="ACF3UE_001062"
     CDS             14716..14937
                     /locus_tag="ACF3UE_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFD3634512.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            14986..15768
                     /locus_tag="ACF3UE_001063"
     CDS             14986..15768
                     /locus_tag="ACF3UE_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFD3634513.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            15789..16496
                     /locus_tag="ACF3UE_001064"
     CDS             15789..16496
                     /locus_tag="ACF3UE_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFD3634514.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDIGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            16758..19556
                     /gene="ileS"
                     /locus_tag="ACF3UE_001065"
     CDS             16758..19556
                     /gene="ileS"
                     /locus_tag="ACF3UE_001065"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFD3634515.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(19605..21131)
                     /gene="zwf"
                     /locus_tag="ACF3UE_001066"
     CDS             complement(19605..21131)
                     /gene="zwf"
                     /locus_tag="ACF3UE_001066"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFD3634516.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSYWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(21146..21793)
                     /locus_tag="ACF3UE_001067"
     CDS             complement(21146..21793)
                     /locus_tag="ACF3UE_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFD3634517.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(21977..22306)
                     /locus_tag="ACF3UE_001068"
     CDS             complement(21977..22306)
                     /locus_tag="ACF3UE_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFD3634518.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            22483..23211
                     /gene="sfsA"
                     /locus_tag="ACF3UE_001069"
     CDS             22483..23211
                     /gene="sfsA"
                     /locus_tag="ACF3UE_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFD3634519.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            23227..24240
                     /locus_tag="ACF3UE_001070"
     CDS             23227..24240
                     /locus_tag="ACF3UE_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3634520.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            24240..25517
                     /locus_tag="ACF3UE_001071"
     CDS             24240..25517
                     /locus_tag="ACF3UE_001071"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFD3634521.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            25580..28282
                     /locus_tag="ACF3UE_001072"
     CDS             25580..28282
                     /locus_tag="ACF3UE_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3634522.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            28434..28751
                     /locus_tag="ACF3UE_001073"
     CDS             28434..28751
                     /locus_tag="ACF3UE_001073"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3634523.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            28781..29101
                     /locus_tag="ACF3UE_001074"
     CDS             28781..29101
                     /locus_tag="ACF3UE_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD3634524.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            29209..30669
                     /locus_tag="ACF3UE_001075"
     CDS             29209..30669
                     /locus_tag="ACF3UE_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD3634525.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            30737..30958
                     /locus_tag="ACF3UE_001076"
     CDS             30737..30958
                     /locus_tag="ACF3UE_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634526.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            30989..31171
                     /locus_tag="ACF3UE_001077"
     CDS             30989..31171
                     /locus_tag="ACF3UE_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFD3634527.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            31171..31584
                     /locus_tag="ACF3UE_001078"
     CDS             31171..31584
                     /locus_tag="ACF3UE_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFD3634528.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            31707..32888
                     /locus_tag="ACF3UE_001079"
     CDS             31707..32888
                     /locus_tag="ACF3UE_001079"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3634529.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(32959..33123)
                     /locus_tag="ACF3UE_001080"
     CDS             complement(32959..33123)
                     /locus_tag="ACF3UE_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634530.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
BASE COUNT        11136 a         5691 c         7054 g         9457 t
ORIGIN      
        1 ttatttttac atgacactca ttacagcagt caatacaaca gatccaatcg ttaaaatcag
       61 cattgtccaa atgacaaatt ttgttacttt agcaaaagta cttgtttgtt ttttttcacg
      121 cattgttttc aacctcgtca ttaattagtt gattcaagtg tacaatcttt tttccatttc
      181 cacaagaggg cttttttata aaaacttccc tttttttaaa taataggtag ttacgataca
      241 aataaataat gttaatagaa ctagccatat aaaggcatca tccctttcag caataggtaa
      301 cttaatgttc attccataga tactgccgac gattgtcggt atagttaaaa taatcgttaa
      361 agaagttaaa attttcataa tattattcag attattcgat acgattgctg aaaaagtctg
      421 attcatttgt tctactagtt ttaattgaat gcgagaagta gtcattgcct gctctgtttc
      481 caccaataca tcacgtaaat gatttttcaa agcatgattt tcttggaaaa gtttattttg
      541 cgctagttct ttcaatgcat ctaaattagc agaagtcgct tctctgaaat aaacgaggct
      601 tttttggata tccatgattt gataaagttg tttgttttca gtggatactt gaagtttggc
      661 ttccaaagta tcgcattgag attgaagcgt agctaaataa ctgttgtaag agagtgtgac
      721 ctgccaaatg aattgaaaga agatattgag attaggcgaa atatcacttt ttggaaaggt
      781 ctggctaaag actttcttta aaaacagtgg ttcatgattc gtaattgtga taagcttctt
      841 tttgggcgtc aaaataatag agagcgggta tgtatccact tgaaaataac cgctaggact
      901 tgttttagca aaaggatatt gtaacaataa taacgctggc tttgtcaact ttgattgatt
      961 gaattcttct gtacgggaat tttctgcatc gtccaatatg gaagtgatgt aatctgacgg
     1021 aatttcaaat tgatgtgtca gctgatgaat ctcttcttga ttaggacgtt ctacacaata
     1081 ccagatcgtt tggtcagttt cctttccggt attacgcagt ttctcattat ctaatgtaaa
     1141 atatttgatc atgattttcc tcctgttgcc tgtttctttt attataacgg atagggaatt
     1201 ggaatacatg gaatgtgttt gtaagatata gaatataact gcataaattt aaataaaatg
     1261 aaacagttgt gtaaagtata tacagtatac ttgaagcaac gataaaaaag gagtttacgt
     1321 tcatgggcac attcacacca cttatcttgt tttggtatat ttacccggta atcgttttgt
     1381 ttggttgcca atttcttgta aaattatttt cgttaaatcg tcgttttaaa ataaaagccc
     1441 ctgatttggc gattcctttt ttgtggggcg gtatgcatgc attgtctaga aatacaggga
     1501 caatttctat cttaccgttt ttctttattt ctgttttgct aatgggaatt tgtattgctg
     1561 ttttccaagc atattattat gaagaaatta tttatccgcg ttatttcaag atgacttggc
     1621 gtttggtttt tctgttgaca atcgtcttgt acgctgtctt gatcattgtg aacatacttt
     1681 cttacctatg aaaaaaatag aaaagctgta aaaagtcttt taaaaggctt tttgcagctt
     1741 gatttttaaa aaaatgttta tgaataaaaa aagttgttcc cggatttccc agaaaaggtg
     1801 gtagaaagtg ggggattgtg gtagactaat tttagttagt ggaggaatgg ggggctttca
     1861 atgttgatgg gtgaattcca acataatatt gatgcaaaag gacgtttaat cgtgccctca
     1921 aaacttcgtg aagaacttgg cgaaaagttt gttctgacac gcggattgga tggctgtctt
     1981 ttcggctatc cgatgagcga atgggaaaat ctggaagcta aactgaacga aatgccgttg
     2041 gctaaaaaag acgcacgtac ttttgtgcga ttcttctatt cggctgccac tgaatgcgaa
     2101 cttgataaac aaggacgaat caatataccc agcacgttaa gaaattatgc agctttgaca
     2161 aaaggttgcg tagtcatcgg tgtatctaac cgaattgaaa tttgggatga gacacgatgg
     2221 caagattttt ctgcagcagc agaagagaac tttgacgaaa ttgctgaaag tatgattgat
     2281 ttcggactat aagaatagga agaggctgac taatgactga aacatttcaa cactatacag
     2341 tcatgttgaa agaaacggta gatggattga acatcaaacc ggatggcgtt tatgtagact
     2401 gtacactcgg cggtgccgga catagtgaat atttattaag ccaactaagt tctaaagggc
     2461 atctgtatgc gtttgaccaa gatcaaaaag caatcgatca cgccaagctg cgtttagctt
     2521 cttatgtcga acaaggtatg gtcacattta tcaaagcgaa cttcagagaa ttagaagaac
     2581 gcttgagtga gcatgtagat aaggtagacg gcattttgta tgatctaggg gtttcctctc
     2641 ctcagctaga tgaagcagaa cgtggattta gttatcatca agatgcaccg ttggatatgc
     2701 gcatggatca gtcagctcct ttatccgctt atcacgtaat taatgaatat tcctaccatg
     2761 aattagtaaa gattttcttc cgctatggcg aggagaaatt ttccaaacaa attgctcgtg
     2821 aaatcgaacg agtacgaaaa acaaaaccaa tccaaacaac tggtgagctt gtcgaaatca
     2881 ttaaacaagt catcccagct cccgcaagaa gaaaaggcgg gcatcctgca aaaagaattt
     2941 ttcaagctgt gcggattgca gtaaatgacg aactcggtgc cgaagaggcc tctttagaac
     3001 aggcaatccg gttattgaaa gtcaatggaa gaatcagcgt aatcacattc cattcattgg
     3061 aagacagaat tgtcaaaagt atgtttaaag aatatagtac ggtacaagat ctaccaccgg
     3121 gacttcctgt catacctgac gaattccaac cagaactgaa agtcattact cgtaaaccaa
     3181 tccttccttc agaggaagag ctaacagaaa acaatcgatc acgcagtgca aagttacgta
     3241 ttgcagaaaa aataagaatg aaagaggagt agaatgatgg cagaattaaa gaaaatgcaa
     3301 gattacgaat atgatttacc tgaattggtg gatcagccgg aacaacaaat gcctgattct
     3361 tcttcgaatc aagaaatcat tcttccacaa tcaccggcaa aacgattaaa gcagatttct
     3421 gctttggaaa aaattgctgt ggcaagcgtg gcgattgcta ttgttgcttt atgtgtttta
     3481 acagttatgc tgcgcacaaa tatcagcgga gctgaaaaag aaatcacgtc aatacaaaca
     3541 gaaatcaatg ataaaaagca agaaaaaacg agtttagaac aagaaaaaaa cgaactttct
     3601 cgtactgaac ggattaaaca aatcgcagaa gaaaaaggat tgtctattaa tgacgacaat
     3661 ttaaggagag tgaagtaaat gagtcttaaa aataaaattc ggcggtttat ggaaaagaaa
     3721 aatctaaatc cgatgaacaa tcgcaaaaaa gtaggtatca ttttatttgc tacgagtatt
     3781 ggattgttct ttttatttgc cgtccgtttc tcgtatatcg ttattggagg tcatgttgct
     3841 ggtacctcat tagctgaaaa aacaaaacag ttgtaccaag gaagtgaagt agtaaaagca
     3901 aaaagaggaa cgatttatga tcgtaacggt gtggcgctcg cagaagatgc ctcctcttat
     3961 tcaattaaag cgatactctc aaaaacatat acctctgggg ataaaaaact gtatgttgaa
     4021 gaaaagaatt ttgataaaat agcagaaatc ctgcataaga atctttctat agacaaaaaa
     4081 gatgcactga atattttaga ggacggcgca aaaaaagagc tgtatcaagt tgaatttggt
     4141 agctatggga aaaatatctc ccaagaaacc aagcaaaaca tcgaagcgga catgaaaaaa
     4201 gaaggtgtcg ctggtcttta ttttgtcgac catcaggctc ggatgtatcc aaatggcgtc
     4261 ttttcttctc attttattgg atacgcagtt ccagacaaag atgagaatgg cttagttggt
     4321 aaactaggtt tggagtctgc ttacaatgat atcttgagcg gtaaagatgg taagattatt
     4381 tatcaaaaag ataattttca aaatcctctg ccaggtacag tggcagaaga agaaaaagct
     4441 gtcgacggac aagatatcta cacgacttta gacagcagac tacaaagtta tttagaaaca
     4501 ctgatggatc aagtaaatga agaatatcag ccagaagaat tgacagcagt cctgatgaaa
     4561 gcaaaaaccg gagaaatctt ggcaatggga caacgaccta ctttcaatcc tgaaacaatg
     4621 gaaggattga ctggaaaaga tgctatctgg cgtaatttct tggtacaaga tagttatgaa
     4681 ccaggatcaa ccatgaaagt tttcactact gcagctgcta tcgaagaagg agaattcaac
     4741 gagaatgaaa ccttccaatc tggaaaaatc caagtagaag atgctacgat caatgaccat
     4801 gactttggtg aaaaaggtgt gctgaccatg cgtcaagctc tttcatggtc aagtaacgtc
     4861 gggatggtca tactggaaca gcgattaggc ggacgatggt ataactattt acaaaaactg
     4921 ggatttggac aaagtactca ttctggatta gatgatgaag taaacggtgc tttacctaca
     4981 ttaaatattg tcgaccgagc aatgagtgct tatggacaag cggtaggtgt gacgaatttc
     5041 caaatgatga aagctttcac ttctattgcg aataacggta caatgattca acctcgatat
     5101 atcagcaaag tggtggatcc ccaaactgga gaagagcgaa caactcaaac agaagttcta
     5161 gggcaacctt tttcaaaaga aacaacagaa aaagtccgtg aatatatgag agatgttgtc
     5221 gaaagcgaaa actacggtag tgcttatggt gtatatagtg tacctggata caatgtatcg
     5281 gcaaaaaccg gaacagccca aatcgcttct gatacagggg gatatcaaac aggagataca
     5341 gcctacctgt attcgattgt ggagatggtt ccttctgaag atccagacta tgtcttgtat
     5401 ctaacaatga aacaccctaa gacatatgat cgaatggcat tggctaaaat cgcaaatcca
     5461 ttgatgaaac gggcaatgga ttttaaagaa actgaagaag attcagatac agaaacaaaa
     5521 acagaaaaag tatccgtagc cgattatcgt aatcttgaag cggacgttgc agcagctgat
     5581 gctcaaaaaa gtggactgca acctgtagtg atcggtaatg gtaaaaaagt acaaaaacaa
     5641 tctactgcca acggtgatca gttgatctct ggagaaaaac tgatcctata tactggtggt
     5701 gataagctga tgcctgacgt aacaggatgg tcaaaagcag atatcatgaa gctggggaaa
     5761 atcctcggta ttgaagttag ttttgatgga gatggttatt gtgtcaaaca agaacttgct
     5821 ccatatgaaa aaatcactga agacaaactt agttttactt tagaagaata agaagagaaa
     5881 taggagagaa aagagcatgg aatggacaca agcattgatt cccattgtca gcagttgtgc
     5941 aatgacaatt gccgcaatgc cgctatttat tggttatttt caaatgaaaa agcaaggtca
     6001 ggcgattcgt gaggagggac caaagtggca caatagcaaa gccggaactc ctacaatggg
     6061 cggcttagtg tttctgatcg gctctatttt gacaggaatt tgggttggag cttggcaaaa
     6121 acagctaact cctactcttt tcatcttgct ttttgtatta gcgttatacg gagtaatcgg
     6181 ctttcttgat gattttataa aaatattcaa gaaaagaaac atgggactga actcgaagca
     6241 gaaattgatt ggacagattc tagggggaat catcttttat cttgtttacc gttctgaagg
     6301 ttatccaggt gtattgaatt tcttcggact agatctacct ttaggaatca tttatggtat
     6361 tttcgctctc ttctggcttg ttggattttc aaatgcagta aatctgacag atggcatcga
     6421 tggattagtt gctggcttag gaagtatctc ttttgcagct tacggtctaa ttgcttggca
     6481 tcagcatcag tatgatgtat taatcatttg cttaagtgtt ttaggaggtt tactgggttt
     6541 cttcgtctac aacagaaaac ctgccaagat ttttatggga gatgtcggtt cattagcgtt
     6601 gggcggactt ttagcggcaa tttctataat gctaaaccaa gaatggacat tgcttttgat
     6661 tggtttgatc tatgttatgg aaacagcaag tgtgatgctt caagttactt cctttaagct
     6721 tacaggaaaa cgaattttta aaatgtctcc aattcatcat cactttgaaa tgtgcggatg
     6781 gtcggagtgg aagattgata cagttttttg gttgatcagc attgtgactt cgttgatcac
     6841 attatggatc gtttggtagg agatgacggg aaatgaaaaa aatatcaaca tatgaaaata
     6901 agaaagtgct tgtcttagga ctcgcaaaaa gcggagtaag tgcggccaaa ttattacatg
     6961 aattgggcgc acttgtcacc gttaatgatg gaaaaccttt tgacgaaaat ccggaagcac
     7021 aagagctgct ttctttaggg ataaaagtaa taacaggtag tcatccaatc gaattgttgg
     7081 atgaagaatt ttcattgatg gtcaaaaatc cagggattcc ctacagtcat cctttagtag
     7141 caaaagccca agaaatgggt attccggtaa ttacggaagt tgagctagct tacgaagtag
     7201 cggaatgccc aattattggg attacaggaa cgaacggaaa aacaacgaca acaacgatga
     7261 caggactact actgaatgca ggagcagatc aaggaattgc acgtttagcg ggtaatattg
     7321 ggtatccagc aagtggtgta gcgcaagaag caaaatcaga agataaaatt gtgatggaat
     7381 tgtctagctt ccaactcatg ggaatcacag atttccgccc tcatatagcg gtgattacca
     7441 atatctatga agcacatatt gattatcatg gtacaagaaa agaatatgtc aaagctaaat
     7501 ggaaccttca aaaaaacatg acagaaaaag attatctgat ccttaactgg aatcagtcag
     7561 aactacaaga attagcgcaa agaacaaaag cacgcgtact gcctttctcg acaaaagaag
     7621 tgttggaaga cggtgtgtat gctgacgatt actcaatata ctataaaaaa gaaaaaataa
     7681 tggaaatatc tgaacttggc gtaccaggta agcataatgt agaaaatgca ctagctgcta
     7741 tttctgtagc aaaattgtat ggtatatcaa atgaagctat acgagaaacg ttgcattttt
     7801 tccatggcgt accacatcgt acgcaatatg taggagaaat ccaaggcaga aaattttata
     7861 atgattcaaa agcaaccaat attttagcga ctaaaatggc tctaagtgga tttgaaacgt
     7921 ctaaggtcgt gttattggct ggcggattag acagaggaaa tacatttgat gaattaattc
     7981 cttcattaaa aggaatcaaa gcaatggtcg tatttggcca aacaaaagaa aagttgatgg
     8041 atgctggaaa aaaagcaggc atcgagacaa tagtaacagc cgattctgta gaacaagcag
     8101 ttcctttagc attagaaaac agtacagatg gtgatgtagt tttattatca ccagcgaatg
     8161 ccagctggga tcaataccca aattttgaaa ctagaggaaa cagattcatg gaagctgtga
     8221 accgattaaa atagaaaaag tagaagcgag cgataaaaaa tgaaaatttt ggttacaggc
     8281 ggaggaacag ggggacatat ttatccagct cttgcctttg tcaattatgt aaagactcaa
     8341 gaaccgaatg ctgaattcat gtatgtggga gcaaaacgag gtctagaaaa caaaatcgtc
     8401 cctgatacag gaatgccttt ccataccttg gagattcaag gatttaaacg aaaaatttcc
     8461 atgcataaca tcaagacggt ccgattgttt cttaagagta tccgtcaagc aaaaaaaatc
     8521 ctcagtgatt ttcaaccaga tatcgttatc ggtactggag gatatgtttc cggagcggta
     8581 gtgtacgctg cagccaaaat gggtattcca acagttatcc atgaacaaaa cagtgtacca
     8641 ggtgttacca ataaattttt aagccgatat gtggatcgga tcgctctttc atttaaagat
     8701 gcggcttcct tttttcctga aaacaaagca gttcttgtag gtaatcctcg agcacaagaa
     8761 gtagcagata ctaaaaaatc agatattttg aaaacatttg atttggatcc agaaaagaaa
     8821 acagtcttga tttttggcgg tagtcaagga gcacttaaaa tcaatcaagc agtatcagtt
     8881 tttttaagtg aatatattcc ttcttcttac caagttttgt atgcttcagg agatagatat
     8941 tatgaagaga tcctaaataa aataaatcct gaaatacaaa atattagtgt ccagccttat
     9001 atcaaaaata tggcagaggt catggcttcc agtgatctgc tggtggggcg tgctggtgca
     9061 acttcgatcg cagaattcac agctctgggg ttaccggcag tgttggttcc cagcccatat
     9121 gttacgaatg atcatcagac taaaaatgca atgagtcttg ttcacgcagg agcagcaaaa
     9181 atgattgcag ataatgaact aacaggtgaa tcactaagtc agacagtcaa cgaaatcatg
     9241 ggtgatgaag aattgcaaaa gcaaatgtgc cgagcttcta aagaacaagg aatccctgat
     9301 gcttcaaaac gtctttatga cttagtaaaa caaataatca aaaaataaag gcggtggtct
     9361 tagtgagtaa gaaaaaagaa ccaaaaaaat tgtctcatcc gtcttctgat gaaaacaatt
     9421 tgactccttg gcaaaaggct aaccgaaaat atctggcaga acaagagatg aaaaaccaag
     9481 agccaaaaaa agaagacata acattagata cacccctttc agattctgaa gaagaaaaaa
     9541 cggttcaaga ggaacagcaa gaagaaagcc agtccgagaa aaaaatcgaa ttttttgaag
     9601 agatcaagca aaagaaaaac ggtggaccat ataacggttc ttttttgaac cggctgccca
     9661 atttaaaaag tcaacggcac aaagtactat ttcgtcggtt agctttgatc atcactgtat
     9721 tgggtatacc gctgattttt ttgatctatt atgtttctcc ttatagcaaa ttacaagcag
     9781 ttgcagtatc aggcaataag acagtcaaca gccaagaaat catctctgat acaaaattgt
     9841 cattaggaga aaatgtttgg ggacagtatt ttcatcgatc tacttatatc gatcgcctta
     9901 aaaaagcaca gccaagaatc gaaacagcaa atatacattt caaagggatg aatgaattcg
     9961 atttggatgt aacagaatat aaagagattg ctttgatcgc aaaaaacaat caatactacc
    10021 cagtgattga aaatggaaca gtattagatg aaaaagtagc aaatcctaca aaaaatctcc
    10081 ctatcttgga agagttcaaa gactctgcaa aaatcaaaga attaacaaag caatacaatc
    10141 agttatcatc agaattacaa aaagcaattt ctgaaatcaa gtacacgcca agagcaagca
    10201 ataaaaatct gatccaattg aatatgaatg acggcaatca agttattgta aatatcaata
    10261 atcttgcgaa ccaaatgaaa tattattcgc aagtagccaa agatatggat gaaaaaggtg
    10321 tgatcgacat ggaagttggt atcttctcgc atccttacgg tagcactcaa gaaacggaag
    10381 aatcgggcca atcggaagaa acaactgaaa gtgaagaaaa tgcggatcaa acaaacgaat
    10441 caagtgaaga ggcagaaacg caaaaagcac aaacacctgg atcgtctagc acaaacggat
    10501 catctgattc aaatgattca agtgaaacaa gtcaaataga agataatcca agtacaactc
    10561 cgtcaagttt aaatgaaaat tgataaaaca actttaaaaa gtaagaatgt actttctaaa
    10621 aaccagtaat ttatggtaga attggaagca gtgaatatat ctattaataa gtatatttta
    10681 aaacggacgc tagttgttcg cttgtatatg gaatagtaag taggagggaa tcccattcat
    10741 ggcaaaaaca ggaatgtatg taggccttga tattggaacg acatctgtta aagttgtcgt
    10801 ggctgaatat atcgacagcc aaatgaatat tattggagta ggaaacgcaa aatcagaagg
    10861 gattaaccga ggcattatcg ttgatatcga taaaacggtc caagcgatac aacgagcagt
    10921 acgacaagca gaagaaaaag caggtatcca gatcaaaggc gtaagtgtcg gtttgccagc
    10981 aaacatgctt gaagtagaaa attgccaggg aatgattgca gttaacggag attcaaagga
    11041 aatcaccgat gaagatgtca gaaatgtggc ttcagctgcc cttgttcgtt caatacctcc
    11101 tgaacgtcaa atcgtgtcaa tattgccaca agattttact gtcgatgggt tcgagggaat
    11161 caaagatcct cgtggaatga tcggcgtaag attagaaatg tacggtctgt tgtttacagg
    11221 acctaaaacg atcatccata acatacgtaa atgcgtggaa aatgccggat taatcgtcaa
    11281 cgaaatggtg attactcctt tagcgctgac tgaatcaatt ctttctgacg gagaaaaaga
    11341 ttttggtacg atcgtcattg atatgggtgg cggccaaaca acaacggctg ttatgcatga
    11401 taagcaattg aagtttacca atcttgacca agaaggtggc gaatttgtca ctaaagatat
    11461 ctctattgta ttaaatacgt catttaacaa tgcagaagcg ttgaaaataa actacgggga
    11521 tgcataccca gaacggacat caccagatga agaatttcca gtagatgtga ttggtcagtc
    11581 agaaccagtg aaagtcgatg aacgctactt gtcagaaatt atttcagctc gaatggaaca
    11641 gattttcaac aaagcaaaag atgcattgga ccaaatcgaa gcattagagt tgccaggtgg
    11701 cgtcgtattg acaggcggag ctgctagtct tcctggtgtt gtggacttgg cacaagaaat
    11761 cttcggcgta aatgtaaaat tgtatgttcc aaatcacatg gggctgagaa acccggtatt
    11821 tacaaatgta ataagtatcg tggattattc agcaaacttg agtgaagtgt atcaattggc
    11881 aaaaattgct gttacgggtg aaacctcagc agctcgtcaa atggtagttg aacaagaaac
    11941 aacaaacaca tatgagagct atgaagcacc tgaagaaaca atctacgatg agccggaacc
    12001 aaaagagtcc ggagaaaatg taaaaaataa aatcaagggt ttctttacaa atatttttga
    12061 ttaattcatc ctgggaggaa taagatatgg aattctcaat tgataataat atcaatgacg
    12121 gcgcagtaat caaagtcatc ggagtcggtg gtggcggtgg aaatgctgta aaccgaatga
    12181 ttgaagaaaa cgttaaaggt gttgaattca ttacagccaa cacagacgtg caagcattaa
    12241 aaaattcaaa agctgaaaca gttatccaat taggccccaa atatactcgt ggtttaggtg
    12301 ctggttctca gccagaagtt ggacaaaaag cggcagaaga aagtgaacaa tccttacgcg
    12361 aagctttaga cggtgcagat atgattttca tcactgcagg aatgggtgga ggaaccggta
    12421 caggtgctgc accaatcgtt gcaggtatcg cgaaagaatt gggcgcattg actgttggtg
    12481 tcgtgacacg tccattcact tttgaaggac cgaaacgtgg ccgttttgct gcagaaggta
    12541 tcgctcgttt gaaagaaaat gtggatacat tattaattat ctcaaataac cgtttattag
    12601 aagttgtaga taaaaagaca ccgatgcttg aagctttccg tgaagcagat aatgttttac
    12661 gacaaggtgt acaaggtatc tctgatttga tcacagcgcc aggttacgtt aaccttgact
    12721 ttgctgacgt gaaaacagtg atggaaaacc aaggtacagc attgatgggg atcggtgtgg
    12781 ctagtggaga agatcgcgta gtagaagcaa cgaaaaaagc aatctcctct ccattgcttg
    12841 aaacatctat tgatggagct gaacaagtac ttcttaacat cacaggcggt ttggatatga
    12901 cattgttcga agcacaagat gcttcagata tcgtagcaaa tgcagcaact ggcgatgtaa
    12961 atatcattct aggtacatct atcaatgaag aaatgggcga tgaaatccgt gtgacggtca
    13021 tcgcaacagg tatcgatgaa tcaaaaaagg aacgcaagtc tagccgacca gctagacaag
    13081 cacaaatgca atcacctgct caaaagactg tattagatat ggatcaagct aaaccaactt
    13141 cttcagaaga agaaaacagt tttggcgatt gggatatcag acgtgaacaa aatgttcgtc
    13201 ctagagttga tgattccaat tttgacaata tcgaaaaaaa agaatttgat acattcaacc
    13261 gcgaagaaac aaaatctcat ggcgatgatg aattaaatac gccaccgttt ttccgtcgta
    13321 aaaaataaag gagaggaaga gcacatgatt gctgacaact tgcagaaaat caagcaagaa
    13381 attcaggatt cgtgtgctct tgttcatcgt gatccgaaag aagttacatt agtagctgta
    13441 acaaaatctg ttgaatccgc tcaagctgaa gaattggtta gagctggcgt tatgaattgt
    13501 gcagaaaacc gagtagataa attattagaa aagaaacaag atttatttga ttttcctgaa
    13561 ataaagtggc atttaattgg taatttacag cgcagaaagg taaaattgat tgtaaatgaa
    13621 attgattact ttcatgcgtt ggacagttta agattagcag aagaaatcca gaagcggtta
    13681 gagaaagaat tatcctgttt tattgaagta aatgtttctg gtgaggaatc aaaacatgga
    13741 atttcaccag atgagctttt accgtttgtg gaatctttag ctgcctgcac aaaaatcaag
    13801 gttgttgggt tgatgactat ggcgcctaaa gaagcttctg atgagcaaat ccataaagtg
    13861 tttggtacgc tgaaagaatt gcgtgatctt gttcaagcaa aaggttatgc ccatgcacca
    13921 tgtagtgaat taagtatggg gatgagtcaa gactttcaaa ttgcgattga agaaggtgca
    13981 acatttatcc gtgtaggaac agcgctattc aaagacgaat aaaggaggaa caaaaatgcc
    14041 gcttttaaac agaggagcaa ttgctaattt tttcggatta gctgatgagg aagagtacga
    14101 ataccaagat tatcctgaaa caacaaaaaa ggctgtacag ccaactaaaa aaaatacaac
    14161 acagaatcaa tcaactcatt ctgtatctgc tgcgaatact catgaaaaac aaaaaacggc
    14221 gacttcacgt cctgtaacgc atgaaagtat tcagccggct gaaaagaaaa aagtaattga
    14281 actacatcaa tcacctacaa aaactgtagc gaaagaaaga acagcttcaa gaacctctac
    14341 acaacctaaa gcaaatcttg ctggaaaaat cactgtaatg gaaccaagag cttattctga
    14401 agctatggcg attgctaaac gaatcattgc tggagaagca accttagtga attttcattt
    14461 agtagaagaa aaacaagcga gaagaatcgt tgattttcta acaggaacag tttatgcact
    14521 agatggagat atcaaacgtg ttggagatga gatttttctt tgtacaccga ctgggatgga
    14581 gattgacagt tcaaccgctc aatcttttgc agatgcgaat ttgtttgatc tgtaagagga
    14641 ggaactacga tttatactat tgcactatta cttcatttac ttcaacgggc agcctatttc
    14701 tatagcatta tcttgatggt atatgcattg ctctcttggt ttccaggcgg gtatcaatca
    14761 gggctaggac gattattagc taagatctgc gaaccgtata tcagtttgtt cgatcgtctg
    14821 cctttgagga ttggaccctt ggatttcaca attttagggg caatcctgat cttgaactta
    14881 gccgtacaag gtttagcaca gatcgttata tggataactg tccatttagt ttattgattg
    14941 aagcaacaaa atctttattc tcagaataga taggagggga aaattttgga tgcaaatgta
    15001 taccagcact ttcgggcaga tgaacgtaca tttatcgatt cggtaggcga ttggattgaa
    15061 caggttcaag gacaatatgc accctatctg accgaatttc ttgacccaag acaatcctat
    15121 attttagaaa cactgattcg acaaagcagt gatttgcgtt tcatgtttta tggcggatat
    15181 gaacaggcag aaagaaaaag atgtttgatt ttccccgatt attacgaacc tgtagaggaa
    15241 gattttgaaa cagcattgta tgaaatccat tatcctagca aatttgccag cctaagtcat
    15301 gggaaaatcc ttggaacttt agtgggaacg gggatcaaac gctcttactt tggcgatatc
    15361 atctcggacg gtgatcgctg gcaagtattt attgcaaatg aggtggatca ttttgttgct
    15421 gcacaagtaa caaagattgg aaaggttgct gtacgcttgg aaccaatcaa atacacagaa
    15481 atgattatgc cgaaagatag ctggacacaa gaaagaggaa cagttagttc catgcgacta
    15541 gacagtgtga tctctgagat ttataatatt tccagacagc ggtccaagca gctgatcgaa
    15601 gctggtaaag taaaagtgaa ctggacagaa aatacaagac ctgattttgt acttgaacta
    15661 ttagatatta tttcagtcag aggttatggc agagtccaga tccaagaact tgaggggaag
    15721 acgaaaaaag aaaagtacag ggtactgttc ggtgtattac gtaaataaaa taaaaaggtg
    15781 gtttactcat ggctttaact ccattagata tccaaaataa gacattcccg acaaaaatgc
    15841 ggggatataa tcaagacgaa gtagatgatt tcttagattt agttgttcgt gactatgagg
    15901 aattgactca aagaaatcga gaattagaaa aagcagtcaa acattctgaa gaaaaacttg
    15961 agtacttcaa tgaattaaaa gatgctttga accaatcaat catcgtagct caagatacgg
    16021 ctgataaagt aaaaacaagt gcaagcaagg aatccgaagt gatcgttact tctgcacaaa
    16081 acaaagcaga tgagttagtt gcgaacgctg aaaaacgtgc acatcaatta acaactgatg
    16141 cagaagaaaa agcaagaaaa atcttgacag atgcaacaga aaaagcaaga cagcttgcga
    16201 cagaaactga agatcttaag aaaaaaacac gagtattcca tcaacgtatc agcttgatgc
    16261 ttgagtctca attagaacaa gtgaaaagtc cggaatggga tgaaatttta caaccattct
    16321 ccagctacgt gactgacagc catgaagtga tcaaagaagt tttagcaaaa cagcttgaca
    16381 atgaaaatga tactgatgta aactcagaca taggagtcat agaagcacct atgacggcat
    16441 ttgatacaca ggctattgat atctcgatcg tgcctggtga aaatgaaaac gagtagaaca
    16501 gaaaagcact ttgttattct taaagcgagc cgatgagagt ggaagttcgg taagacactg
    16561 catggtgaaa gatcctctac ttgagacctg cttttccgaa attagagtaa gaagcagcgg
    16621 ctgacctcgt tattggtcac agagagtttg cactagatag atgcaactaa atttgggtgg
    16681 taccacggca tgttcgtccc ttgcggctga acatgctttt ttgtgtccgg aaaacaaata
    16741 aaggagtgta tggttgaatg aaaatgaaag aaaccttgca attaggaaaa acaaaattcc
    16801 ctatgcgtgg taatttgcca aaccgagaag gcgagtggca aaaagaatgg gaagaaaatc
    16861 gaatctacca aaaaagacaa gagttgaacg aaggaaaacc tagctttgtt cttcatgatg
    16921 gacctccata tgccaatggt aatatccatt taggacattc attgaataaa atcagtaaag
    16981 acattatcat tcgttcaaaa tcaatgtctg gctatcgtgc accatatgtt ccaggatggg
    17041 atacacatgg attgccgatt gaacaagtat tggctaataa aggcgtgaaa cgtaaagaaa
    17101 tgtccatggc agaatacttg gaaaaatgtc gtgaatatgc actttcccaa gtagataagc
    17161 aacgagcaga tttcaaacgc ctaggagttg caggagattg ggaacatcct tatgttacat
    17221 tagatccttc ttatgaagct gcacaagtac gcgtatttgg taaaatggct gaaaaaagct
    17281 atatttacaa aggattgaaa ccaatttact ggtctccgtc aagtgagtct tctttagcgg
    17341 aagctgaaat tgaatataaa gatgtaaaat ctccatctat ttttgtagct ttcaatgtca
    17401 aagacggcaa agatattctt gatgaagata cagcttttgt catttggacg acaacaccat
    17461 ggacattgcc agcaaaccaa ggtattgctg taaatccaaa atttacgtat gtattggtgg
    17521 aagccgatgg ccgtaagttt gtcgtagcga aagatttgct agaaacagtc caatcagaaa
    17581 tcggttggga aaatgtaaca gttctaaaag aatttgctgg acaagaaatg gaatatatga
    17641 ctgcaagtca tccattctat gaacgtgaat cacttgtgat tttaggcgat catgttactt
    17701 tagacgctgg tactggatta gtccatactg ctccaggaca tggggaagat gactatatcg
    17761 ctggtagcaa atataaacta tctgtagtgt cacctgtaga ctcaaaagga ttgtttacag
    17821 aagaagcacc tggatttgaa ggtatctttt atgacaaagc aaatcctatg atcactgatc
    17881 tattaaaaga aaaaggagct ttgctgaagc tagatttctt tactcatagt tatcctcacg
    17941 attggcggac gaaaaagcct gtgatctatc gggcaactcc acaatggttt gcatctatcg
    18001 ataaattccg tcagaatatt ttggatgaag tagaaaaagt agagtgggtt atcccatggg
    18061 gtaaaacacg tttgtataat atgatccgtg accgcggcga ttgggtaatt tcccgtcagc
    18121 gtgcatgggg agtaccactt ccgattttct atgctgaaaa tggagaagca atcatcacac
    18181 cagaaacaat cgaacatgtg gcaaaattat ttgctgaaca tggatcaatt atctggtttg
    18241 aaaaagaagc gaaagaactt cttcctgaag gatttaccca cccaggttct cctaatggcg
    18301 aatttacaaa agaaaaagat atcatggatg tctggtttga ttctggttct tctcatgaag
    18361 ctgttttacg tcagcgacca gaattatcat tcccagcaga tatgtattta gaaggatcag
    18421 accaatatcg tggctggttc aactcaagta tcacgactag tgtggctatc aatggtgtag
    18481 caccatacaa atcagttatt tctcaaggat ttgctttaga tggtgaaggc cgtaagatga
    18541 gtaaatcttt aggaaacatc attgcaccag aaaaagtgat caaacaattt ggtgcagata
    18601 tccttcgctt atgggtatct agtgtagatt atgaagcaga tgttcgtgtt tctatggata
    18661 tcttaagtca agtggcagaa gtatatcgta aaatcagaaa tacgatgcgt ttcttattag
    18721 cgaatacaga agatttcgat cctaaaaaag atactgtttc gtacaatgat ttacgttctg
    18781 tagacaaata tatgaccgtt cgattgaacc aagtaatcaa agaaatccga gaagaagggt
    18841 acgacaaata taacttcatg catatttacc gtacagttat gaacttcttg acggttgatc
    18901 tatcgtcatt ctacctggat tttgctaaag atgtagttta tattgaagca gaagatgatt
    18961 atcaacgtcg ttgcatgcaa actgttttct atcaaacagc tgtagctttg acaaaattat
    19021 tgactcctat cattccgcat acagcagaag aaatctggtc attcctgaaa gaagaagagg
    19081 agtacgttca gttaagcgag tttcctggtt atgaagagtt tgcaaaccaa gaagaattga
    19141 tggatacctg gactgctttc atggacttcc gtgataatgt cttaaaagca ttggaagaag
    19201 caagaaacag caaattgatt ggtaaatctt tggaagcaaa actaactgtt tatccaaaac
    19261 aacaagttcg tgaaatgtta aaagctttgg atgcagatat tgcacaatta ttgatcgttt
    19321 caccagacta ctttgaagtt atggcagcag atgaacaagt gccagataac gctatggtat
    19381 ttgatgatgt tgctattaca gtggaaaaag cagacgggga aacttgcgat cgctgtcgcc
    19441 aagttcgtaa agatgtagga gtagatgaaa aacttcctca tctatgcggt cgttgtgcaa
    19501 aaatcgttga agacttctat cctgaagctg tagctgaagg attcgaagaa aagtaaaagg
    19561 gaaaaggggg tgtgacatgt tctttgtcac accccctttt gttatcaatc gtttaatttt
    19621 ccacgttcac gataccagtt atctggttgc cagatccatt cgaatccgtc tttttcaagt
    19681 agttcgaaag ctgctttagg tcccattgat ccagctttgt agttgggaaa atccggttgt
    19741 gtttggtccc aagcttttcg aatgacatcc acgatatgcc aagattgagc gacttcttcc
    19801 caataagaga agttcgttcc atcaccattc aacgcatcta atagtaattt ttcgtaagct
    19861 tctgggctat tttcaaccat ttctgcacta tttctaaatt ccaatttgat tggttccgtt
    19921 tcaaatcctt gccctacttc tttcccattc aaggataaag aaaatccttc agttggctga
    19981 atatagatcg ttagaacatt aggtggaagt gtcgtatcgt cacatggttc atcgacagat
    20041 gttttgaata cattaacagg aacttgtttg aatacgatgt tgatccgagt ccctttttca
    20101 gtcaaacgtt tgcctgtacg tacatagaaa ggaacacctg accaacggaa gttatcgata
    20161 gtgaatttgc ctgcgacgaa tgtttcagtc tctgattgag catccacttt gtcttcttcg
    20221 cgatagccct tgaattgtac accatccaat tcaccttgag catattgccc gcgaacgaag
    20281 ttttctaaca cttcttcttc gttataaatg cggatagctt tcaatgcttt gatcttttct
    20341 gtacggattt ctttttcgga aaatgctact ggcggttcca ttgcaagtaa tgctacaacc
    20401 tgtaaaatat gattttgcac catgtcttta agtgcgccac tatgatcgta gtagcccccg
    20461 cgatcttcta caccgaggtt ttcgccaaaa gtaatttgga tattgtcgat atagcgattg
    20521 ttccattgag cctcaaaaat attattggca aaacggatag ctgagatgtt ttggatcatt
    20581 tcttttccta aataatgatc aatcctgaaa atatcttgtt ctgggaatac ttctctgatt
    20641 tgctggttca attcaaaagc agactggtaa tcagaaccga acggtttttc tatgatcaaa
    20701 cgattgaagc cattttttgt cataatattt tgtgatttca aatgagaaac gatcgttcca
    20761 aaaaattgag gtgccatagc caaataatag acacggttac cgtttaattg atagtgtcca
    20821 tctaatcggt cagacaattc ttttaatgtc tgataatgcg ttgaatcatt tacatcatgg
    20881 gattgatagt aaaaatggct tgcaaaggta gttgcttctt catctgaagg attcaatgca
    20941 cggattgttt ctttgacaac ttcacggtag tgctcatcgc tccagggacg gcgagcggtt
    21001 ccgattacag caaaatgctc gcctaaattt ccttttctgt aaaggcggaa caaagacggg
    21061 tacaatttac gctgggctag gtcacctgta ccgccgaata tcgtaaacaa tacatttttt
    21121 tcattagaca tgtggataca ctcctttata ttttatcgac aaaaatcgtg ctggccgcct
    21181 taaagctgac ggggattttc tttctatcat tttggatagt gatcggtcct tcataagctg
    21241 cgatgtcaac gatctcatat tcttcgttga tattcaggtc aatagtgact aagtaatcca
    21301 acaattcttt ttcatcaagc actcgtgcga tacgcacttt tgtaccgaca ggataggact
    21361 ccaatgtttg tcggcgttct tcatggacaa cttcctcttt tttaggaatc gatcctccat
    21421 gaggacaatg ttcaggatga ttcaaatagt tttctaaatg atctgcaaga tgttccgaag
    21481 tcacatgttc caatacttca gcatcatcat ggacttcatt ccagctatag tctaaatgtt
    21541 caactaaaaa aacttcccat aagcgatgtt tgcgaatcag actgctagct ttttgcagtc
    21601 cgcttgcagt caattgtaca ccttgataag gggaatgttc tacaagctct tctttcacaa
    21661 gtttagaaat catttcactg acagatgcag ctgagacatc tagactagat acgatttgtt
    21721 tattgttgac tttcgttgta tctccaccta gttctaaaat gattttcaaa taatcttctc
    21781 gatttggtgt catattcgat catcctttca tggtaaaaaa ccatcattag taagtgtaac
    21841 aaaaaaaacg ttaattgact atttttctaa ataaaaaaca aaggattttt agacgttttt
    21901 acaacaaaaa acgaaagatg atagagaaga ctcattcttt cgtttataaa ggatatatat
    21961 atacattggg agggatctat ttttcagata acaacttata tgaagtgtct gcagattcgt
    22021 cataaagagt ttgttcggga taagaaaaga taagataaaa accatactga tcacgtacga
    22081 ctaaacgata ttcatctatt tctaccacag atgtgccaag agactgaccg ttgatcaaaa
    22141 acgtgtaatc agatgtaatc tgtaattgtt gtttttgctg gctatcacta aagaaccatg
    22201 taccttgata ctttgagagt ccttctgact tttccgcttg ttttttcttt ttcaagtaaa
    22261 taaaacttga gagaacggta atgagtgaac caagaaaata gatcattttt tttatcacca
    22321 aatcactcct ttatgagaaa ataatcgcat agacatattc tttcttcttt atttcattgt
    22381 accgaataaa agctaaaatt tctctaagac tttcgactgg tttttttact gtttttctac
    22441 aaattatgat aggatacata gtaggaagaa aggtgacata atttgaagta tcagcaagtg
    22501 gaaatagctt tttttattga ccgcccgaat cggtttatag cacattgtat gaaaaaagac
    22561 ggagaaataa ttattgcgca tgtcaaaaat acaggtagag gaaaagaggt cctgatacca
    22621 ggcgctgaag tggctattgt atttgctcct ggacctaaac ggaaaaccgc ctatgatctg
    22681 attgctgtaa aaaagaaggg tgactggttt aatatcgata gtcaattgcc taatcggctg
    22741 gcaattgatg gtattttaga cggcacgatc cttttaccag gattaactgg tccatttacg
    22801 gtatacaagc gtgaagtaac ttatcttcac tccaaatttg atatttattt agagacggtg
    22861 gtcggacaaa aagcatttgt tgaagtcaaa ggtatgacac ttgaaaataa agcgattggt
    22921 gcttttcctg atgcgcccac actcagagga ttgaaacata taggagaatt aacgtatgcc
    22981 gcacaagatg gttatgccgc ttatgtcttg tttattgctc agttcgaaca tcttcatctg
    23041 gcaacgatcc atgaagaaat gcaaccagca ctagctgata tggttcgaca tgcgcagcaa
    23101 agcggagttc aaatcctcgc ctataattgt caagtatcgg cagatgaggt aactgtcaag
    23161 caggccattc catttgatgt agatatccct tttgaagatc ctatacaata gaaagaaggt
    23221 aaaataatga tcaacttagg tattatcgga acaaattgga ttactcatca atttgtccaa
    23281 gcagctttaa gcacaaaaaa atatgaattg acagcggtat attctagaca tttggaaaaa
    23341 gcacaggaat ttggttctca ttatgaaggg gatatcgaat tcgcaacaga tttgaagact
    23401 tttttcaata ttactcatat ggacaccatt tatattgctt ctccgaatag tcttcacttt
    23461 agtcaagcta agcaagcaat tttggcagga aaaaatgtga tagttgaaaa gccagctttt
    23521 tcgacgccaa aagaaatgga tgaaatcatc catttggcaa atgaacacaa tgtgtatttt
    23581 tttgaagcag caagaaatat ccatgaatca ggttttaaaa agattgccga ttacttacca
    23641 ttaaaagacg agataatcgg tgcaaatttc agctatatga aatattcttc gcgctatgac
    23701 caagtattag atggagaaga accgaatatc ttctcgactc atttctcagg tggtgcattg
    23761 atggatttag gtgtttacct tgtatatgca gctgttgctt ggtttggaat gccaaaagaa
    23821 gtccattatt tcccaagaaa gatttctact ggtgtagatg gtcttggatg ggggatctta
    23881 cgttatgaga attttgatgt atcgatccag ccaggtaaaa tcggtgattc ttatttaccg
    23941 tcagagattt attttgactc aggaacgcta gtgatgaatg gagtcaatgc aattgaacaa
    24001 gcacaatttc atgatcgcgc gcataaagaa atcattgatt tggcggtaac agctgcagaa
    24061 aatccaatgg cagatgaagc agaggatttt gccaatgtca tggctcatcc gaaagatcca
    24121 gcttggggat tgttgtatga agagtggatc gagctagcta gaaatgtgaa ccaagtgatt
    24181 tatgatttaa gaaaaaatgg cggcatcaaa ttcgatgcag ataatgagga agatttttaa
    24241 tgaacgaatt tgtacaagta tttcccgaaa attggcagaa aaaatatgag gataaagggt
    24301 ttatctcacc ttctcttatt caacgagcag tttttcagcc actaagtaat aaacaaagta
    24361 tagtagcggt ttctcctaca ggttcaggta aaacactggc ttatctttgg cctctactac
    24421 taaacgtgga accaggtgaa gcaagtgcgt tggtcatttt tgcttcttct caagaactag
    24481 ctattcaagt agcagatgtt gcacgtgaat ggggaaaaga caaagagttg aaagtccaat
    24541 ctttggtggg cggagccaac gtcaaacgtc agattgaggg tttgaaggaa aaaccagaaa
    24601 tcttgattgg tacaccagga agaatattgg aattgatgaa agcaaaaaaa ataaaagcac
    24661 atcaagtgaa aacaatggta tttgatgaag cagaccagct atttgacgct gggaacagcc
    24721 aaatcattga tcaaattctt catcaagctc caacagagta tcagctagct tttttttcag
    24781 cgacagcaga tcgttccctt gaaagcattg aaaaaatcac tgggaaaacg tttgagacaa
    24841 ttgacgtgac agcagaggac gattctcgaa aaggactgag acattacttt ttacgtgtac
    24901 cgatacgaaa gaaagatgac tacttgagac gtctcacgca tatagaagat tttcatggtc
    24961 tgattttctt taatcaactg actgaattag gcgtaatgga agaaaaattg ctgtatagag
    25021 gtgtaccggt aggaagtctg gcctctgatc agaacaagct actccgaaaa gcagcgctag
    25081 aacaattcaa aaagaaaatg gtcagagcac ttttgaccac agatgtggcg gctagaggtt
    25141 tagatattac aggtcttcct tatgtagtga atgcagaagt tccgttaagt gaagaagctt
    25201 atttgcatcg ttcgggaaga actggtcgaa tgggtaatga aggaatagta attacactcg
    25261 tacaagataa taatctaaga gatttaaaac ggcttttacg tccatcaaat ataacacttg
    25321 aagagatttt tttatacgga ggtaagctgc aaactgagca gccaaccaaa gaagatgcag
    25381 ctcctgcagt aaataaaaag tatgcgaaaa ctttttctgg aaaggagcag aacccagaat
    25441 ataacaaaga aaaaataaga aaaaaagtta aaaataaatc aaaaaaagag agaaataaag
    25501 gagcaaggcg caaataagcg cctttttatg ctatgattat gaaaacggga acaaaattgg
    25561 ttgccagagg aggggttatg tgaaagaacg tcaagaagag atcttgcagc tattgacaga
    25621 aaaccaacaa ggattgacag caagtgatgt agctgagcgc ttaactatcg atcgaagcaa
    25681 tgcaagccga tatttaagtg aactatacaa ggcccatcat attgtaaaaa ccgctggccg
    25741 accagtcgtt tactctttgc caacggaaaa gtcaaaatct gatgaagtgc atgtcgactc
    25801 ttctacgcaa gtgacttttg aaacactcgt tggagaaaat gattctttaa aagtcagcat
    25861 acagcaggca aaagctgcga ttctttatcc accgcggggg ttgcatacga ttatttttgg
    25921 agaaactggt acagggaagt cgatgtttgc tgaatgtatg tatcattttg caatcgattc
    25981 agagatgctt tctgcagatg cgccatttgt ttctttcaat tgtgcggatt atgctcaaaa
    26041 tccgcaactg ctctttggac acatctttgg gatcaaaaaa ggggcttaca caggagcagc
    26101 tcaagatagt cccggtctaa tagccaaagc agacggcggt atattgtttt tagatgagat
    26161 ccaccgttta ccgccggaag ggcaggaaat gctgtttact ttcattgata aaggtattta
    26221 ccgtccgctt ggagaaagtg cacaagtaca tgaagcatct gttcagatca ttggggcgac
    26281 gactgaatct tcagaaagtt tcttatctac gttcaatcga cggattccta tggcaatcac
    26341 cttgccgaat cttgcttcac gttcactgga tgagcgttat gaaatcatct ctctttttat
    26401 caaacaagaa gcgaatcgtt tgaatcaacg tatcgatatc gaaaaagaag cgattcttgc
    26461 cttcatgctt tatgatgcgg aaggaaatat cggtcaagtg aaacgagact tgaaactagt
    26521 ctgtgcaaaa tcttttttac attaccgtac tcatcatgag aaaaagctaa tcattcgaaa
    26581 agaagaactt tcccttcaag tacaaaaagg attactgaaa atcaaggaaa taccggaacg
    26641 tctcgaccga ttcatggaca gcaaaagtca gtatttgaca tttgaaccag gatttgctga
    26701 tgttgtctgg tcacaagatc cagaacgaaa catgcaggtc tataacgata ttgaggaaaa
    26761 agtcacttct ctttccgaaa ccggtgtgga gaacattgat ctagagaccc tcatttcaaa
    26821 agatgtggat gcttatttcc agacatatgt caaagaattg actaaaagtt cgattcccaa
    26881 agatcttttg ccagatgaaa tctggcggtt aaccaatcaa ttgtatgatg tggctgaaaa
    26941 acggttagac cgtatttata atgaaaaagc tcgttttgct tttgctttgc atctgcaaag
    27001 tacattggat cgtgtgagag aaggtcatat gatcgtccac ccagatttga ataacgtacg
    27061 gaaaaatttt aagagggaat tccaggtagc aatcgatctt tcaacgatca ttgaagaaga
    27121 agaacaagtt gagattcctt ttgatgaaat cggctttatt agtatgtttc tttctatcaa
    27181 tctaggagaa agtgagcctg ttaaagaaaa caaagtagat gttctcatat tgatgcacgg
    27241 cagacagact gcttcaagca tgttggagat ggcacaagaa ctattaggaa caaaagtagg
    27301 gaaagctttt aatatgccac tggttatgga agttcaaaca atgtatgaag aagtgttaca
    27361 atatgtcaaa aactatcaag agcatttgac gaatggccta ctcttgttaa cagatatggg
    27421 atcattaaac accttcagtg atttgattta tgaagagact ggcattcgga cgaaagctat
    27481 cacgatgaca agtaccatga ttgtgataga agcgatacgg atggcaagtg ttggaagaag
    27541 cttagaagat atttatcaaa atatccagct ttcctttgaa tcgatcgtac gtgatcagtt
    27601 caaagcggaa aagtctgaaa ctttacagcg taaaaaagcc gtaatcgtga catgctttac
    27661 tggtgaagga gtagctgcca aattatatca gcgtattatg ccagtgatta atcaaaataa
    27721 ggtagaactg atccagatgc agtttttaga acgtgaatca ttcaaaaaac acatcgatgc
    27781 cttattggaa gaatatgaga tcaaagcaat tgcgggaaca gttgatgttg attatcaaaa
    27841 tatcccattt ttttcagcct atgacgtttt tgatgatgaa aaactaaata ttttaaagcg
    27901 tatagctgat gatgagatcc cgacagctaa aattgtcgat tcacttgctg gatcattaag
    27961 cgatgtcttt tctattgatg aactgatccg ttcattgcaa aagacagttc agcagatcca
    28021 gaccgatttg tcgattatcg tggaacctgg agtagatact ggaatcgtta tccatttagc
    28081 cttcatgtta gacggattga tcaaacaaga aagccatcgg caatttgaga aactgtctat
    28141 tttctcaaaa atttatcgtt tggaaatgga tatcgttcgg gcaaacttga tggcactaga
    28201 acgaaaatat caggtaaaaa ttccagaaga tgatatcgca tttcttacac aaatgtttct
    28261 tgaaaataaa ataaaaaaat gaacacacta atcatactgt ttacacacta aacatctgtg
    28321 tgcgcactat aaaaaagagc taaaaagcat gaaaacgcta tttcagctct tttttttatt
    28381 ggcatgcttc ttgcgttata taaaagtgta aaaaaataaa aggagtgtta aaaatggcaa
    28441 aaaaaacaat catgttagtt tgttcagcag ggatgagtac gagtttattg gtcacaaaaa
    28501 tgcaaaaagc agcagaagaa aaagggatgg aagccgatat ttttgcggtc tctgcctcag
    28561 atgcagataa taatttagaa tctaagaatg tcgatgtatt attattaggt cctcaagtac
    28621 gtttcatgaa agctcaattt gaacaaaaac ttgcgcctaa aggtattcca ttagatgtca
    28681 tcaatatgca agactatggc atgatgaacg gagaaaaagt tcttgcacaa gcagaaaatc
    28741 taatgaaata aatcaagtat gcagttgggg gtataacaac gtggaagatc aacaaaacct
    28801 agaagccatc atggggttaa tcatgtttgg cggtaatgca aagagcgatg caatggaagc
    28861 gattgcggct gctaaaatcg gtgattttga gttagcggat aggaaaatcg ctgatgcaga
    28921 agaatcactt atacaagcgc atcatgcaca aacagacatg ttgacacaag aagcacaagg
    28981 aaatcatatg caagtgacat tattgactgt tcacagtcaa gatcacttaa tgacatctat
    29041 tgcgtttact gatttagcaa aagaaatcat cgaactttat cgtcgcgtat acagcgaata
    29101 aatacaactt cttttttgaa cggaagaaga aaaatttttg aacggatttt ttattttgtt
    29161 ataaggagaa ctctctttat ataaaaaact tataggagga agtaaaaaat gaacggacta
    29221 tcaagttgga tggagaaata catcctgccg gttgccgcaa aaatcggagc gcaaaaacat
    29281 ttagttgctt tgcgtgatgc ttttatcggc acactgcccg caacaatggc gggatcagtc
    29341 gctgtaatga tcaatgcaat tattcgtgat ttaccgcaac agtttaacag tacctatgct
    29401 gacagtttag cagcagacaa aggaatcttt gccgtattga atgtcatcat cggaatcaat
    29461 ggttttgtct ggaacggtac actagcaatc gccggattga tctttgcctt ttcttggggg
    29521 tataatcttg cccgagctta tggagtaaat gatctagctg gggggatcgt tggtttagct
    29581 accttgattc aaggtatttc ctttggtcca gcattatcag cagcattaga tgtgaatgtt
    29641 ccttcaaatg tcgcagatgc aatcaatagt tctgagattg gtgcaacgat tgcagatggc
    29701 acactgtcag ttggattatg gggttggcta aaactagatc atttgaatgg aaacgcttat
    29761 tttacagtta tgatcatggg agctatttca gtcattattt tttgtaaatt gatgcttgcc
    29821 aacattacga tcaaaatgcc tgattcagta ccaccagcag tatctaaagc atttgcagcc
    29881 attttaccag cgacgatcgc tttatacgtc attgctatta tcaattatat cgtaggtcgt
    29941 gtagctgatg ggcaactgat cattgatttg gtgcaaaaat atattgcaga accattccta
    30001 ggattatctc aagggttggg agcagtattg atcgtcacag tatttgttca agtattctgg
    30061 ttctttggta ttcatggacc aaatgtattg gcaccagtgc tagagggaat ctggggacaa
    30121 gcacaactaa tcaatattga tattttccaa aaaggttata acggaaaaac tggtacacca
    30181 gccgtgttag atgcaatcga agatggaaaa gcttatatgt gggtccgcgg atcgttcgat
    30241 gcttttgcat ggtttggcgg atcaggcgga acgatcgtct tactgatagc tatcttgatt
    30301 ttctctaaac gtgcagatta tctaacagta gctaaattat ccattgggcc tggtatcttc
    30361 aatatcaacg aaccagtgat gtttggtctg ccaatcgtat tgaatgcaat catgtttatc
    30421 ccattcttga ttgctccagt agtagcaaca gcaattggat ggacagctac ttatcttggc
    30481 ctagtcgctc cggtatcgca gcaagtcaca tgggtagtac cgccgttctt attgtcattc
    30541 ttagcaacag gagcggattg gcgggcaccg atcgtaacat tagtatgtat ggtcgtgact
    30601 ttcttgattt gggcaccatt tgtcatctct gcaaacaaaa tggaccctgc cgcaggcgaa
    30661 caacaataag atgaacgtga ggagcgggac gctttaagtt tcgttcctca taatgaattt
    30721 tcgaggagga actgaaatga ttacaattgc cagtgcaatg caacaagatg aaatcaaaga
    30781 attgttagaa ggatacaatg aagaaggaat gacttttaca tttaaagaaa aacaaggaat
    30841 caagctgttc tttgaaacaa gtgcagaaga tccggaagtt gcggctaaaa aagcaaagga
    30901 actaatcaaa gcacagcctt ggggaacagt cctttatttt caatcaacag ctgtttagaa
    30961 aatggtttaa aaagatagga tggttgagat gataaaaaac ggtttatttt tatgtagtat
    31021 tggttctttg atcgtgttgt atagtttgaa tccacattcg caaaggtatg atttgtatag
    31081 tatggtcaca ggtctttttc taacaggatt aggaatctat ttcttcatga aggggaaaaa
    31141 aagagaagaa gcaaaggaga aaaataacta atggaaatca cgaaaaaatt aaatattcca
    31201 gcatcgtttt tttacgataa agttatggac tctgtccttt tcgatgtacg taaagcgacc
    31261 ggcaaatcag taactagaaa acagctgaaa aatttggagt acgtcaaaca attctcgcaa
    31321 aataaccggg ctcgcataaa aatcgaagaa gtcattgaaa accagtctta taagtttcgt
    31381 acatcgacaa cgaagaatga attcgtcgtt cattatcaaa tcaaaccatt ggacgattcg
    31441 acctgtgagg ttcattacac agaaaaaatg gagtcttatg gcatgcttca aaagttgaat
    31501 gatatgcttt taggaacaat cttgatgtat tttaaacgga gacgtttcaa aaaaatgcta
    31561 gatatgatcg aagcaacgta ttaaatcaat gaaacatggt actatttagt tattgaaaaa
    31621 tgaagtaagc tagaaggaat ttttcatagg aagatagatc tttcctgcga atcctcacta
    31681 gcttttttgt aggaaggggc agcaaaatga caaacaaagt aagagagcta ggtgtatctt
    31741 cgattgagga aatgtttgat ttagccactt atgcatttaa tggggcagat acacctgaaa
    31801 ggcgagaacg ttttcgtaca cttgcggaga attcttggaa ttacggattt tttgatgagg
    31861 aggatcggct aacaagtcaa gtcatggcga ccccttttcc agtgaatttt tacggacaag
    31921 agtacctaat ggccggcatt ggctatgttg cttcttatcc agaagcaagg ggacaaggcg
    31981 ggatcaatca gatcatggaa aagatccttg aagattgccg tgatcgtaaa gtaagcttat
    32041 cttatctggc gccattctcc tatcccttct atcggcgcta tggctatgaa caatcatttg
    32101 ataaaatcag ttatcaacta aacagtcgtg atgtgccgtt tatcaaaaaa aaatctggaa
    32161 aaataaagcg tatggatttt gaagatgcaa aagctgcaat cagaagaatt tatgaacaga
    32221 tgccggaaaa ccaacgagct ggtctgaagc gcgaagactg gtggtatacg tataaattca
    32281 agcaaaaagg caattaccag tttgctttgc attttgatga taatgaggaa gcaacgggat
    32341 atatcgttta tcagcttgca acgtcttcct ttattattgc ggagtgggga tttttggatc
    32401 atgatgcttt ttgcagcctt gttcgcttcg taagttctca caatggtgct tttgaaacat
    32461 ttgaatattc atgcggctac ggcggtaatg atcaaaatta tctattagaa aatccatttg
    32521 cttctgtaat gatcacacct tatatgatgg cgaggatcgt agatatttct ttgtttttgg
    32581 aaaattatcc atttaaaaag agacaagctg catttgccct acaaatagaa gaagatcatt
    32641 atgcgaaatg gaatgaagga atcgtggaag taacaatcga aaatggaaaa aatcatctct
    32701 caaaagtaga acaaacaaaa ctcccaatcg ttcgaggaag tatccaacat atcacgcagc
    32761 tattattagg gtatcgtaaa gtggaagagt tggtattcca agaaagaata caggtgacaa
    32821 aagaatatga agaaacgtta agctcaatct tgccacagca acagccaatt cttaatgact
    32881 atttttgata aaaaacgggt gatgacaata tttttgtcac cacccttttg tttttcattt
    32941 ggcatttgaa ggaaaatgtt aaagtaaatc ctcttttttc gtaaatttga attttttgtt
    33001 ttcttttgtt ttagggtttt cttttttgtg gtcttggatt gcttctttcg taatcttttc
    33061 ccgatttttt ttagatgaat ctaagcgttc tgcgtatact ttttcttttg gcttatcatt
    33121 cattggaaag gacctcccta cattatttca ttctacctct agtttatcat ctgttaagga
    33181 ctagtggaaa cgttttgcct aacttataag ctgatttttt tagcagataa gcttgcaagt
    33241 aaaaaacaaa caagctacaa ttgatttatt gaaattgttc ctgtagctca gtaggataga
    33301 gcaatcgcct cctaagcgat aggtcgctgg ttcaattc
//
LOCUS       DAXLPC010000024        33126 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.024, whole genome shotgun sequence.
ACCESSION   DAXLPC010000024 DAXLPC010000000
VERSION     DAXLPC010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.024"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(93..950)
                     /locus_tag="ACF3UE_001081"
     CDS             complement(93..950)
                     /locus_tag="ACF3UE_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3634531.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(1058..2361)
                     /locus_tag="ACF3UE_001082"
                     /pseudo
     CDS             complement(1058..2361)
                     /locus_tag="ACF3UE_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            complement(2358..2867)
                     /locus_tag="ACF3UE_001083"
     CDS             complement(2358..2867)
                     /locus_tag="ACF3UE_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634532.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(3042..5177)
                     /locus_tag="ACF3UE_001084"
     CDS             complement(3042..5177)
                     /locus_tag="ACF3UE_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFD3634533.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(5260..6915)
                     /locus_tag="ACF3UE_001085"
     CDS             complement(5260..6915)
                     /locus_tag="ACF3UE_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3634534.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(6917..7231)
                     /locus_tag="ACF3UE_001086"
     CDS             complement(6917..7231)
                     /locus_tag="ACF3UE_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFD3634535.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            7401..7661
                     /locus_tag="ACF3UE_001087"
     CDS             7401..7661
                     /locus_tag="ACF3UE_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFD3634536.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            7675..7989
                     /locus_tag="ACF3UE_001088"
     CDS             7675..7989
                     /locus_tag="ACF3UE_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFD3634537.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(8719..9273)
                     /locus_tag="ACF3UE_001089"
     CDS             complement(8719..9273)
                     /locus_tag="ACF3UE_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFD3634538.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(9399..11327)
                     /locus_tag="ACF3UE_001090"
     CDS             complement(9399..11327)
                     /locus_tag="ACF3UE_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFD3634539.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            complement(11633..12349)
                     /locus_tag="ACF3UE_001091"
     CDS             complement(11633..12349)
                     /locus_tag="ACF3UE_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFD3634540.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(12350..14173)
                     /gene="glpO"
                     /locus_tag="ACF3UE_001092"
     CDS             complement(12350..14173)
                     /gene="glpO"
                     /locus_tag="ACF3UE_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFD3634541.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLIPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(14187..15683)
                     /gene="glpK"
                     /locus_tag="ACF3UE_001093"
     CDS             complement(14187..15683)
                     /gene="glpK"
                     /locus_tag="ACF3UE_001093"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFD3634542.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(15819..17279)
                     /locus_tag="ACF3UE_001094"
     CDS             complement(15819..17279)
                     /locus_tag="ACF3UE_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3634543.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(17269..18564)
                     /locus_tag="ACF3UE_001095"
     CDS             complement(17269..18564)
                     /locus_tag="ACF3UE_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3634544.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVKEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(18896..19573)
                     /locus_tag="ACF3UE_001096"
     CDS             complement(18896..19573)
                     /locus_tag="ACF3UE_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFD3634545.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(19603..20694)
                     /locus_tag="ACF3UE_001097"
     CDS             complement(19603..20694)
                     /locus_tag="ACF3UE_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFD3634546.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(20795..21229)
                     /locus_tag="ACF3UE_001098"
     CDS             complement(20795..21229)
                     /locus_tag="ACF3UE_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFD3634547.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(21813..23270)
                     /locus_tag="ACF3UE_001099"
     CDS             complement(21813..23270)
                     /locus_tag="ACF3UE_001099"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3634548.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENL
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIEDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(23267..25162)
                     /locus_tag="ACF3UE_001100"
     CDS             complement(23267..25162)
                     /locus_tag="ACF3UE_001100"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFD3634549.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(25220..26995)
                     /locus_tag="ACF3UE_001101"
     CDS             complement(25220..26995)
                     /locus_tag="ACF3UE_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFD3634550.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYLVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESSEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(27045..28541)
                     /locus_tag="ACF3UE_001102"
     CDS             complement(27045..28541)
                     /locus_tag="ACF3UE_001102"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3634551.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     EIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRIWKEEDCAPVMLDGDEQYLQANTVDYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(28735..30357)
                     /locus_tag="ACF3UE_001103"
     CDS             complement(28735..30357)
                     /locus_tag="ACF3UE_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFD3634552.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(30807..32120)
                     /locus_tag="ACF3UE_001104"
     CDS             complement(30807..32120)
                     /locus_tag="ACF3UE_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFD3634553.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLLGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFMGFMWILNVK"
     gene            complement(32365..32589)
                     /locus_tag="ACF3UE_001105"
     CDS             complement(32365..32589)
                     /locus_tag="ACF3UE_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634554.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(32609..33031)
                     /locus_tag="ACF3UE_001106"
     CDS             complement(32609..33031)
                     /locus_tag="ACF3UE_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3634555.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
BASE COUNT         9461 a         7107 c         5512 g        11046 t
ORIGIN      
        1 ataactaaag agagatggga catgtagtgg cactcaagaa ttagattttt cagtctaact
       61 tcgaggtact ctaccttccc atcctctctt ttttatttct ttttgcggat gattccgtaa
      121 gctgctgcga ctaacacacc cgcccctgct aaggaataac tgacagaagc tgttttttca
      181 tttgtttttg gcaaagtctg acttgttgat ttggatggct ctgtcgtttg ctgaactgtt
      241 tctgtcgtgc ttccagaggt cactgatttt tctcctgccg aatgcaaaat atcttttatt
      301 cgttggaaac tagctgctaa gtcagctttt tttgcttcaa aatcattagc aactgtttgt
      361 gcttcgctga tctttccgtg gattgcttga cttgccgctg tgatatccgc ttgagtttga
      421 cttagctttc cagaagctgt ttgagcaacc tgatttaatt gctgattgaa ttcttttgct
      481 tgttggatct tcccgtcaag atctgtttgg acagcttccg cttttgcttt cgcttcggca
      541 agctttttct caagttgtgc acggtcattt cccactttat ttttaagatc agctaaatct
      601 tgatcgattg ctgcttggtc ttctttcaat ttgttttttg cagcttctaa tgcttcttcg
      661 agttcttttc ttttattttc caagtcttgc aaatgatcga tttggtcaga agaggtagaa
      721 ctatttattg atgtatcttc tgaagatgaa atcgtttctc ctgaattatc tgtcggtaca
      781 ttggaagtca tttctgtttc cgaggcaccg ttttcagcac cagaagagct tatagttgtt
      841 gaaggttctg tttgagcagg ttcagaagtt tccgcaaaag ctgtctgtcc caataagaaa
      901 atactggaaa cagcaattgg ccagattaac ggcttcattc tttttttcat cacttttccc
      961 atccttacta ctttttaact aatttcttat tataagcaaa aatgtttgga agaaccataa
     1021 acacaacagg ctgtttgtct aaaaaacggt gcatctttta tttttttgta cgttccgggc
     1081 ttttccatgt cccgcttcca taacctaaaa tcgttttgac tgctggaatg aaagtcgtca
     1141 cgatcgttat cgcgttcact atccagaaca aaagcatata tagtggtgcg aaaagaaggt
     1201 atttcaattt tcttcgtcga tcatctacaa tcagcgaagc tagcaactgg aaaaatcctg
     1261 cgaccatttc aaagcagatg aacacaaaac tgaatgtaaa agtaatataa atctgttcgt
     1321 agtttccttg atatacataa tgcccgatta atccagcaaa aagaactacg gaaatacaaa
     1381 agaatattga ccagacaata ctcaatgttt gatcaatgaa gatgatcgtt cttccaatat
     1441 gtttaaaagg atggagcatc acttttttga aattcgtcag ccagacttct gttccacctt
     1501 ttgcccaacg ttttctttgt cgatatagca tcttcaacgt cacaggtact tccatgaaaa
     1561 agataatctc aggagcaaaa acagataacc agtcatttaa ctgatgatcc caagcaatac
     1621 tgatgtcttc tgtcgctcga tcttgtctga atccgcccac atcgatcaag gcttcttttc
     1681 gatacatcgt atttgctcca ctgtacgcat aaagaccacc gaaaacagct gactgtgttc
     1741 gtttaatgat gcccacgata cttgagaatt caaccgtttg agattttgca atcaatttgg
     1801 tacgattttg gacatccata tttgcagtga ccgcagcaat atgtcttgca ccagggcgaa
     1861 tgaaataatt cacataccta atcagtgcat ctggctccgg taccgtgtct gcatcattgc
     1921 ttaaaatcaa tttccctttt gcaaaggcaa gtccgatatt aaacgcgtgg gcttttcctt
     1981 tatttttttc gatccgaacc acacgaagat tagcgtattt tttcatcagt ctagctaata
     2041 tttctggtgt ttggtccgtt gaaccatcgt ctgtcactaa tacctcatag ttgtgataat
     2101 tcaatttcgt catcaaatac tcgattgtat cttcgatcac aatttcttca ttatgggctg
     2161 gcaccatgat cgtgatgaac ggttcgacac tcaagggaac atctacccat tctttttgct
     2221 tatgtttgta taaaaacaca taacaccaga caccaataaa ccatacaaat ccgcctaaaa
     2281 tcggataaga aacgagaaaa aatacataat agacaaacaa gtatctaaga ataaattacc
     2341 tgtatgggtg attgagatca tttcagttcc accccatttt ctttatacaa atctgcaatg
     2401 aatgtcgtat ctagattttt ctcttcggag acagaataaa aacggaccgt ttctctctct
     2461 tcttttgttc caaaacgttc cgtatacact tcttcaagta attcttgtct ttttttcaat
     2521 ttttcatctt catattcaaa agatttattt acttttttgt atagatttcg attgttccac
     2581 ctagtcaata caaatgaggt aatcaggaaa ctgaaaaaaa tcaatacaaa aaagccgatt
     2641 aagaaataca gcattttctt ttctgataaa aaagcgtaca aggaaaaatc cttggctctt
     2701 tctggtctcg ttaatgggaa aaagacccat ataaaaggaa gaacaacgat catccatcct
     2761 aaaagagcca ctaacgtttg ccaaatcttt aaccagtaat taccttttga aaaatactta
     2821 tctttcacca aaattgatgc aacttcttct cttgttactt ttttcatatc ctcacctcac
     2881 gtttttttgt tacgacgtag gagtttacca tacatttcat ttcttttcac ataaagtgtt
     2941 cctaaatttt tcctaagaaa aagaacaaaa catttctcat cagtaaatga aaaatatttt
     3001 gttcttttta tcagttgttc tttttatttt ttatctctta attatgttgc tctttccaat
     3061 acgacaatgc ttttcattcc tctagatatc gccgtgtaca tttgtctgcg tcttctttgc
     3121 tcatctccat cgttttcaaa tggatataag attacatgat caaattccag tccttttgct
     3181 agactcaaag gaatgatttg gcagttttct aatccatatg aatttttttt aatcgattct
     3241 tgtagcgttt gggtttcctc ttctgtttgg gtgataactg ccgctttttc tccttttaga
     3301 gaaaccaaaa tctcagctag tattttcaac aattcttcag aggatcgaaa agagcggtat
     3361 tcgggttctt ttccttgcgg tcggatcgat acgatgtcga tcttctcttg atccacagca
     3421 taggttttga aaagctctgt gattgctccg ctagaacggt aactatttct aagatcatac
     3481 cgatggatcg gcagatggta gtcgtcgaaa caacgcataa tatcagcaaa agtagtggaa
     3541 gaattaaaga ttgcctgatt ctcgtcacct actaaagtaa agtgagtttt tggaaataat
     3601 tcgatcaata gacctaattg tgccagggta taatcttgta cttcatcaat caatagatag
     3661 cgaaatgctg gtacatttac cttttcaaca agtaaatgac gaatagctaa tataatgact
     3721 gcttcatcaa cagtacgtgt gggttgccaa gcataagctg agccatatcg tttttcataa
     3781 attctttcaa acaactgatg ctcatccacc catgccattt cttcgatttg tctggttatt
     3841 tttcgatatt ttttttgtaa aagtttcctt gcataagcta caatactttg ttccgaatca
     3901 tcagaaatca atttaccgaa taattccaac tgcctatctt ctgtcaacga gagtacctga
     3961 ttctgcacag caggactttt tgcttgtttc aaaagatgat tcttccattc gctcatcagt
     4021 gcctttttcg ttgcttgaag cctatcgatc aatttaggat gagcaggaac tttctcatat
     4081 attttttcga tcgttttttt agaaaggact gtttttccat ttttagtaag tccacggata
     4141 aaattcggat gatctaaaaa caaaggatct gattgtttta gattatcgat aaactttttg
     4201 ctacgcaaac gttctgtctg ctccgataca ttttctcccg tgatacgttt gaaataagcc
     4261 tcttcacctt ctatttcctc tgctgaaagc tgtgaaacca gctgtatgat ggttagattc
     4321 agtggatttc tttcacctaa tgatggtagg acattcgaaa tatagtcgat aaaccgatga
     4381 ttaggtgata gaatcagcaa gtcatcggat gtcatcgtat ctcgatataa atagagcaga
     4441 tacgcaatac gctgcatgat agcagaggtt ttaccacttc ctgctacgcc atttaccaag
     4501 atattttgac ttttcacatc ccgaatgatt gtgttttgtt ccgattggat cgtagcagtg
     4561 atagccttca tttcattggt ctcatcttgg cctaagactt ctaataatac gtcatcttga
     4621 atagctacag acgtatcaaa aaacttgacc aaacgatctc tttccaaaag aaattgtcgt
     4681 ctttctttaa taaccgtatc gattttattt tgacgaaccg tataagaaga tggaccaatc
     4741 atgttattgt aaaaaagttc ggcaattggt gaacgccaat cataaacaag attttcatct
     4801 gcatcatctg tgaaatttgc tgtaccgata taaaaggatt cttttggctc attatccaga
     4861 aagtctacaa cgacttttcc aaagtaggga cttttcaata aacgttcgat ctttgctagc
     4921 tgattttctg cgtttttctg tttgatattc atctgatcga tttctctatt tttcatttca
     4981 atcatcgaaa aagtatccag gttatctaag taactgtcaa aattcaatcg aagctcgcca
     5041 gccatttctt tcaacgactg gtttccttct atttttgccg tatccatcga ttcccgcagt
     5101 tcgttttttt tatcaattag cttttgatac acgttcttca gatatgcttc ttctaactgt
     5161 ttttgtgtgt tgaccataca cattctcctc tttttttaaa gtggtggaac cgattagttt
     5221 acctctttta agagtcgaat gcaagctttt taacgagtat catttgttag gatatatcag
     5281 ttcttcaggt cggacagttt gatataaaga aaatgcacca tcaaggtttt ttacgtggta
     5341 gccagactgc ttcaagattc tttccgctag atagctacgt aatccgctat gacagctgac
     5401 gatatattct tgttggctgt ctaattcatt taatcggtcc cgaagttcat tcaaagggat
     5461 atgtttggct tccttgaatt tgcccttttc caattcttct gctgttcgca catctaataa
     5521 aatttttcct tttgctagtt ctgtcggcaa ttcatgccat tgtacggttt cactaagccc
     5581 ttctgcaatg ttcattgctg catatcctag catgtttact ggatctttgg ctgagccaaa
     5641 tggcggtgca tacgtcaatt ctaattccgg taaatcgaag atcgtcaaat gccctttgat
     5701 tgctgttgct aaaatatcga tccgtttatc cacacctttt gccccaacac cttgtgcacc
     5761 ataaatctcg ccagtctctg gatggaagat caacttcagt aaaatatctg ttgcttctgg
     5821 ataatagctt gcatgatctt ttcctgatac atgaatgact tcaaaagaca gttcgttttc
     5881 tttggctgtt ctttcactta aaccggtgga tgcggcagtc attccaaacg ttcgtataat
     5941 tgctgttcca ataccgcctt gatttcttcg agaaattccg gaaatcgtgt ccgcaacttg
     6001 tctaccttga cgattggctg gtgaagcaag agaaataagt gcatcttttc cagtgatttg
     6061 ctgttttaca acgatagcat cccccaccgc ataaatatca ggaatattcg tttgataacg
     6121 ttcgtctact aggatacccc cgcgtatgcc taattcgatt ccagcggtca ctgctagctg
     6181 gttatcagga cgaacaccaa tggataaaat aactaaatca gcagggatgg tacgcccatc
     6241 atccagtcgc aatcgtttcc cgtggtcttc aaatccagcg acagcatgag aagtaatcac
     6301 ttctactcct tgatgagaca attctttttc tataaaagct gccatttctt catccagtgt
     6361 tggaagaata tgtggtgctt gttcgatcac catgacttct aaacctcttc tttttaggtt
     6421 ttctgccatt tccaatccga tgaatcctgc accaacgatc acggcacgct ttggctgttt
     6481 ttctaatgca tgcatcactt tatcgatatc tggtacattt ctaatagaaa aaacattgtc
     6541 ggcttctgtt atccctggaa tcgatggaac aactggtttt gcaccaggag ataaaaccaa
     6601 tgcatcgtac tgttcaatgt gtttttgacc ctcatgtacg acttctaccg ttttgttttc
     6661 gggaaagatg gctgtcactt catgatttgg acgcacatct aaacaaaaac gagcggataa
     6721 tgattctggc gtttggacaa gaagattttc ccgttcactg atttctcccg aaagataata
     6781 aggcaagccg caatttgcaa aagaaacata cggtcctttt tcaaaaacaa cgatttctgc
     6841 atcttccatt aatcggcgaa gccgtgtagc agcagacatt ccacctgcta cacctccgac
     6901 aataacgatt ttcatcttat ttccctccta ctgttcgatc aaaccattga ttcatgccac
     6961 cacgtacatt cactacatca taaccagatt tctttaattc tttagctgct tgtttactcc
     7021 tcatccctga ttgacaaatc acatagacgg tcttttcttt gtctccatca tatctgttta
     7081 tactttgtaa tggaacattt ttagctcctt ttatatgccc gccccggtat tctgcaggtg
     7141 ttctaacatc aagtaacgct ggattttcca aaagcttttc ctttaattct gggactgtta
     7201 tcgattttat tgattgaaat agcaaattca ttttctgcac ctcatttaca tttttataaa
     7261 tacctcatgg ggtatattaa acaggagctt tattaatatg tcaaccagaa tgactcttca
     7321 tttttttcac tactttttat atttgcataa aataccgata aggggtatta tctaattata
     7381 aaaatagagg agaatgtgtt atggagattg ataataaaaa tatcctgaac cgtttgaaac
     7441 gtacagaggg acaaattcgt ggtatccaaa aaatgatcga agacgaaaaa gaatgtatgg
     7501 atgtcatcac tcaattaagc gctgttcgtt ctagtattga tcgcgtaatg ggcatgatcg
     7561 ttgcagataa tctgaaaaat tgctttgaga aacctgatag taatccagaa gaacaagcgg
     7621 ctaaactaga acaagcgatc aagatgatta ttaaaaagta aaggaatgat ttcaatgaaa
     7681 gtcgttttcc atattgatga attagaaaaa tggtcagaaa cagggaaaaa cgtaaaaaac
     7741 ctgataaaag cttctccaga aacgacgatt gtcgtatctg taaatggcat cgcgattacc
     7801 ggttatctag actctgccaa tgcagaattc ttagatttgc aaggagtcgt ttttcacgct
     7861 tgcgccaatg ctatgcgtgc taatcatatt tcagaaagtt ctttacctga acaagtaatc
     7921 gttgtaccag caggtgtcct tgatttagtt gaactgcaat cccaaggtta tgcttatatc
     7981 aagccttagt cagtagaggt tgcgacagaa gtgatcagct tcaagaaatt tcggcttatt
     8041 tttcgaagaa gctacttctg gaaaaccgtg aatcaaaggt tgtgaaaacg ctgtcctgca
     8101 tcaagtaata agaacagcca aacaaaaata gcttctcata tttttcgttt ggttgggctt
     8161 attaccgcag atgcaagctt ttgaacaccg tttaaggaag aggttgtgaa atcagcggtt
     8221 tgacctaagt attagagaaa aaaacgggaa aatagctcct catattttgc cgttttttga
     8281 gctaataccg aaggtcagct gattgaacac cgtttaagga agagattgtg aaaaagtcgc
     8341 ttagtttcga gtattaagaa aaattttgtg aaaatggatt tctacatttt tgcataaatt
     8401 tggcttaata ccgagaaact ggcttttgaa taccgtttaa ggaagaggtt gtaaaatcag
     8461 cggtttgacc tgagtattag agaaacaaac ggaaaaatag ctgctcatat tttgccgttt
     8521 tttgagctaa taccgaaggt cagctgattg aacaccgttt accaagaggt tgtgagccta
     8581 ccatttaact ccgaatcaca agaaataatt tcaaaaacaa cttctcctgt ttttggtttg
     8641 gttggcttat tatcgagaag tagctactgg gagtctattt atcaaaaaaa ggaatgcgac
     8701 ataggtcaca cccctttttt attttctttg aaacatcttt cggtactcga cagcatacaa
     8761 gacaaaagat tgtaaaagac cgtaagtgat gacggcaaaa atgactctca cccacagcgt
     8821 tggtaattct gggaaaagca gcaaaaggat catgccaaca tagatgacag cagtcgctac
     8881 tttgccatac cacttcgctc cacttaattt gatattttta gatagcccga ttaatccagc
     8941 tacaaacata aagccttctt ttatcaagaa tagaccaaac aacagccaaa gccacggtcg
     9001 ataccatgcc atagacaaaa tcagaaaaag ttgtgtcaat ttatctgcaa acggatcaag
     9061 caccttccct aagtctgtta cctgattata tctccgagca atgaccccgt ctagataatc
     9121 agacaaacct gagacaacaa tgaccgctcc tgctatataa aatgactgtc tcagcacaaa
     9181 ataaagataa atcggcagca aaaaaatacg gaatatcgat aaaagattcg gaatcgtttg
     9241 tatttcttta cgccagtctg tgcttaattt cattttatcg ccctacctcc tcagcactct
     9301 tttcttttta ttttagctta cacggggaat aaaaccaatg atttcactgt ttttattttt
     9361 ctttacagcc actgatatta tgagctaatt tgagataatc acttgctgtt ttcatcgttt
     9421 actcttcttt cttcctgtcg tttgcgcatt tcttttacta gtactttatg agcttttttt
     9481 gatcctcgct ctaggtcacg ctgccgttta cgtgttttat aatcgataaa cagactgtct
     9541 aaatcgtaac ctgtcgggta cagatcttct gctgaacgca ccagacgaac acgctgacga
     9601 ggcacgtgga ttattttttt gtctaaatat acatcaatcg tatcttcacc tatatcttca
     9661 taaactaacg cttctttttg gtattcattg acaaatatcc gatcaccttt tgcaaagagc
     9721 tggcgttctt ttttattctc cttcctattt gtaactgctg tcttaggaag aaattctttt
     9781 ttctgtgtcc gataggcttt ttccgccaag taacgctctg cttgatggat caatttcatc
     9841 gacatatcca ttttatgagc aatccacaaa gcttggcttt ctcctgtttc tccaacccgc
     9901 aactgatatt taggacgaag tgcttcccga tcgaaagcca tagcagccgg cacaaaatct
     9961 tcatgatctc cggcgaattt cttgatttct ccataatggg tcgtggcaat gatcaatgcc
    10021 ccttgctcat acatagattc catgattgcg atcgctagtg cagccccttc atttggctct
    10081 gttccactgc caatctcatc taaaagtacc aacgtattcc tttttatctt tttcaaaata
    10141 gcagcgatgt tttgcatatg accagaaaat gtactcaacg cattttctaa attttggtgg
    10201 tcaccgacat cgacgaaaat ctcatcaaag acagcaagct ctgtcccttc ttttgccgga
    10261 acttgcatac cgaacatcgc catcaaagtc aataaaccga ctgtcttcaa cacgactgtt
    10321 ttgcctccgg catttgctcc ggtgataatc aagcctcgat agtctttacc gatttcaaca
    10381 tccaatggta ccgcatgctc aggtaaaaat ggatgtctgc cttgcttgat aatgatatgt
    10441 tccgatttat tgattctagg tgtgcttcca ttgatttctc ggctaaattt tgcccgagca
    10501 aagatgatat ctaacaccgt gatcgtttcg atcaataaat cgatcacttc ttcgttttct
    10561 gcgatagcac cagtcaatgc cgccaggact tgatattctt cactgatttc ttcagctttt
    10621 aacaactgat agtgttcatt caatttagaa atcacagttg gttcaataaa aaccgtcgtt
    10681 cttttatttg attcatcgat aatcgttcca tctattttat ttttatagct ggctttgata
    10741 ggaatcgtat agtattcgcc tttttgaaca atcattgctt cttggatcat ttctttgttt
    10801 ttcggatgac gcaagaattt cagtaatttt gactggattt ctttttcgat tagttgtaat
    10861 tgtttgcgta ctttacgcaa attacgtgac gcgtcgtcac tgactttatt attttttatt
    10921 ttctggtcaa tcaactcttc tacatttatc aaatcaggaa gatgtttgct ataagcaaac
    10981 aacaagggtg tctggtattg attcttatca aaaaactttg tgatcatccg actgcttcta
    11041 agaaaatccg catattcgat caaatcggtt ggctgcagaa tcaacccttt tttgacttgt
    11101 tctgtcagtg catcgatcct cggcaacccc ataaatggaa catgctgact gctttctaag
    11161 atcaagcgtg cttctcttgt ttcttcttga cgatccaaga cagtttgtag gtttgtcgag
    11221 accgtcatat cgctgattcg ttttttgcta tagtttccaa ttgctcttgc ttggatttcc
    11281 tttttgatcc gatcaaattg taattgacta atcatttcgt tgtccatatt ctctcctttt
    11341 cttgaagaga tacctgtccc aaaataaata agggcctaga gataaataaa aggatagaac
    11401 acagcttaaa aaagtcatgt cctatcctta ttagaataca aagatattgt tttcctgaca
    11461 ggtaccgttt cataagcaca ccaaataaac tttgtttatt ggctattcga cttactgatt
    11521 agataccagc tacactcaca aaacataccc cattcttcta ggtcttattt attttccact
    11581 taactatagc aagacacatt ttggttgtca aactttagta tgttttatag atttacacca
    11641 ttaatgaata gacacctacc gcgataattg ctccgatcat tggacctgcg attggtaccc
    11701 atgaatatgc ccaatctgaa gttcctttat tagctattgg caataccgca tgtgctaatc
    11761 gaggaccaaa gtcccgagca gggttgattg catatcctgt tggccctcct aatgaaagac
    11821 cgatggctaa gatcaatcca cctacagcga atacgttcgt tccaggtgca aattcgtttt
    11881 gtccaaaagc tagcaaccca agaactaata caaatgtacc aattaattct gtgatcacat
    11941 ttgctggata attccgtata gcaggacctg ttgcaaacgt tcctaaaatc gcgctttcat
    12001 ctttcgttgc attccaatgt ggcaaataag aaagccaaac aagaatggcc cctgcaaaag
    12061 ctcctaaaac ttgcgcaatg atgaaaggaa cgacaagatt ccaactaatt gcccctgtca
    12121 tcgccatagc tagagagact gcaggattca aatgagctgg gcccatgaat ccagaaatat
    12181 agacagccat tgttacagcg agtccccaac caaatgcgat gacaatccag ccagaagcct
    12241 gtgctttact tttgtttaaa ttcacagccg cacacacacc atctccaagc aaaactagga
    12301 tcagtgtccc aataaactcc cccatgattt gagtcatatc actgttcatt tatttctccc
    12361 cctttagttc ccgcagatct gattctgcaa tcaatgcttc taaacgttta gtctgttgcg
    12421 ccttctcctc ttctgtccat tcaaaatatc cagcaattgc atcgatcaca ggttgcttga
    12481 tctcatcaag ctgatctcgt tcaaacaaca gatgatttgt acgacgaatg agataatcgc
    12541 ctggggccaa aaccatttct tcttctaaac cataacgtaa ccgagctgac tcagcgagac
    12601 tcaaaccagg ataaggtgcc atttcttttg ctaattcaaa gatacgtcgg gcattagtcc
    12661 cgtaaaaatc agcgatataa gtagcatctt cttcctctaa accggctgct actccttctt
    12721 ttgctaattc tgtcactgtt tcttctaatt tagttggatc gaagtttcca cctgaaatct
    12781 gatatttttt agagtcgatt tctttcgtct ctattccgta ttcttctttt aataattggc
    12841 gtatcaatcg caaagctcct tctgccatct tacggtaatc ggtgattttc ccaccagata
    12901 aagtcagcaa accatctggt tctctttcta aagaactacc tctggaaatc gtagaaggtg
    12961 ctttttcatc acggctgttt tccaaatggt tcaacacgtc ttctacttca gcacgagaaa
    13021 ctttgttttc cttatattca cttactgtat cgacaacttt attgaagctc ttgtctgaaa
    13081 tcgatccatt atctccacca ttgtaatcag aaccagaatt accaatcaac agtggacgaa
    13141 gtcctgccca gcttgcttcg atatcattca atgtgatatt tgcttctgga tagcgatgat
    13201 tgatcacatc caatagataa tctacatctt cttgtgtgac tttcggatcc gtaaaatctc
    13261 cttggtaatc cgtatctgtc gtaccaaagt aagtcttgtt ttctcttgga atagcaaaaa
    13321 ccatccgccc atcttgcttt cctgtatcga agtatgtggg ttgcggtaca ggcagttttt
    13381 tcgcatctac aactaaatgg atccctttag ttggacgcat tttaggagag actggacgcg
    13441 taaaattcaa gtttcgtact ttatctaccc aaggaccact cgtattgatc actaattttg
    13501 ctttgatttc gatcacttca tctgtcagca ggtcacgagc tttgacgcca acgatttgat
    13561 cgccatcata taaaaagcca accgctttca ttttacttac tagataagcc ccatcttcgg
    13621 cagccttttt gatattatca atcactaaac gggcatcatt gttgcggaaa tctagataga
    13681 cacccgcgcc ttttagccct tcttttttca aaaacggttc tctttccaat acttcttctg
    13741 gtatcagcgt ataattctca tatttggttc ctgtcacatt tgccagtttg tcataaaggt
    13801 ccattgctac tttgaccgag aacatattga aggttgttgc tccttcgccc tcatagattg
    13861 gcaaaagcat tggatctggt tttgggatgt gtggggcaat actttgtacg actgcacgtt
    13921 caccaactgt gtcagctact acttccacat caaatgtctt cagataacga ataccgccat
    13981 gaacaagttt ggtcgagcga gaggaagtcc cttctgcaaa atcctgcatt tcgatcaatc
    14041 ctgttttgat tcctgatgct gctgactgga ctgccacacc ggcaccagtg attccgccac
    14101 cgatgatcaa cagatccaat tcttcttgct gcattttttg aatgctatct tgtcttgtct
    14161 tgtttgaaaa catatggatt tcctccttat tcaaatgctt gggtagcttt tactgctttt
    14221 ttccaaccgt tgtaaagttt ttctcggcgc tcttcctcca tttgaacttc aaatagcttg
    14281 ccagcttcat aaaattcgcg gatctcgtct gtatctttcc aataaccgac agctaatcct
    14341 gctaaaaatg ctgcccctag cgccgttgtt tccaagtttt ctgctcgttg gatcggtaca
    14401 ttcaagatat ctgtttggaa ttgcatcaga tattcattgt ttgctgcacc gccatctact
    14461 ttcaatacag gaatcttgat tccagtgtca tcttgcatcg tatcgatgat atctctcact
    14521 tgataagcaa tcgactgtaa agtagcttta atgatatctt cttttgtcgt accacgtgtc
    14581 aagccaaaca tagcccctcg tgctgcctga tcccaataag gagcacctag cccaacgaat
    14641 gcaggaacaa cataaacctc atcttcgctt gtagagcgtt tcgctgcgtc ttctgaatcg
    14701 ctagcttttt gcaacatttg aagtccatct ctcagccatt gaatcgaaga accagccaca
    14761 aaaatacttc cttctaaagc atagtaaacc tttccattta tgccgtaacc aattgtcgtc
    14821 aataaattat ttttggataa ttgcggtttt tcaccggtat tcatgacaat aaatgaacct
    14881 gtaccataag tattcttgac catgcctggt tcgaatgcca tttgtccgaa taatgcggct
    14941 tgctggtctc ctgccatccc tgaaattggt gcttcgcttc cataaaaatg ataaccttgc
    15001 gtataaccat aaacttctga gttagaagtg acttttggta acatcactcg aggaatattt
    15061 agtaaatcta aaatctcctg atcccaatct agctgatgga tattgaacaa catcgtccga
    15121 ctggcattcg agtaatcagt aacatgtgct tgtccatcgg tcagtttcca tactaaccaa
    15181 gaatcgatcg ttccaaacat caattcgcct ttttcagctc gttcttgcgc gccttctaca
    15241 tgatcaagaa tccagcgtat cttcgttgct gagaaatagg catcgatcac taaccctgtt
    15301 ttttcgtgga aaaattcttg atagccttca ttttttaagt tatctgcaat tccagctgac
    15361 tgtctggatt gccaaacaac tgcatgatag attggacgtc ctgtatcttt ttcccatatt
    15421 actgttgttt cacgctggtt cgttatgcca atcccagcaa tctgatttgg tttgatccct
    15481 gattcgatga acgctccggc aataactgac tgtacagaat tccagatttc atttgcatca
    15541 tgttccaccc aactttcttg cgggaaatat tgcgtgaact ctttttgaga actgccgatg
    15601 tgtcttcctt tcttgtcaaa gataattgct cgtgagctag ttgtaccttg gtcaatcgcc
    15661 atgatatacg ttgattctgt cattgtgatt ccctccatta tatgcaaacg ctttctttaa
    15721 ctactcttat catactactg ttttaaaaaa agaaactgtc aaaattttat tctttttttc
    15781 tttttttgac agttttttat tatgaagcta ttttttaatc aattcttttc ttttttcagc
    15841 gtctctattc ttcttttcaa tcgaataatg tcgtaaggtg acgcaaattc tgacagataa
    15901 tattcacact gttttttgtt tctctggcaa aatgtgatca ccaaatcata ttctttacct
    15961 tcttcataac ttccaatctc aataccgccg attcccctca gttctctgat cagatattgt
    16021 tgaaaagcaa tacgataaat cggcagactt tctaaatcga ttccaatcac tactggtttt
    16081 gcaatataaa aatcgatcat caaaagaaca ttggcatact ggatcatcag gtaactaagc
    16141 tcactatctt cagctctttt cctcggcaat tgctgcaccg ctgtttcctg taatttcgcc
    16201 agtaactgtg ttaaggaatg cccgagcatt ttctgctgct gttccaaaag ccgatcacgc
    16261 tcatagactt cgatctttcc aacaaagaaa aaccattcat tgttgatctg ggaaatttgg
    16321 tagcctactg ccttttcttc tttgattttc aaacgacgag gacgataatg ccataacatc
    16381 gtttcccgaa tgtaagtatc taaaacagcg gttggtaact ttttgctccg tgtcaaatca
    16441 tactgataaa atatttcttc gtctactatc gaaaaagaaa caaaaaagct gtaaaacatc
    16501 attgtttcgt atacattcag ttctgctgct gttcgactaa gatgcatcac gatgattgga
    16561 tcgattgctt gataaagccg gtccgactga tagagtaatt tcttttcttt caaagttgcg
    16621 tacgtacttt tttcattcaa tagtcttttt ttcgtaatcc cgagccagca agcaatctgt
    16681 gcttctgctg atgccgtaaa cgttgtttct aatacacggt ccaatcctag aatgaacggt
    16741 cttttttctg gtgtattttg caaaaaaagc ggtcgctgat cttccgggat atattggaat
    16801 agttcataat aaaaatatcg tatctgtagc tcttctccgt ataattgacc gtttttgatt
    16861 tgtaatccaa attcctctaa gagctggttc aattctttga tctttcgaaa aacagaagac
    16921 tcactgatat taaacgctgt cgctaatcga acgatggata cttgctgatg ttctaataaa
    16981 tagacgagca tcttaaactt taagctttcc tgcaataaaa acaatagaat tttttccaaa
    17041 cttacatctt cgtccaacac aagcagcgcc tgatactcat ttcgctgtac ttctactttt
    17101 ttttccatca ttcggccaat caattcaata tcttccaaat attgatcaaa cgaggctttt
    17161 gacagttgga catgctctct caaaccattg atagaggctg ttcccccttg cagaacaagg
    17221 tttcgcaaaa tcaggatctg taactgctct tttctttcta ataatgcttc aatcttcata
    17281 ggcagtattc gccacctttg accacaccat atctggcaca cggtattctg gctggaaaaa
    17341 tagctcatgt tcttctaact gttcaaacgt ccatccttct tttactgcaa ttgtcagttg
    17401 gtcaagaagg tggaacatct cttttttgct ttggagctgt gctccaagaa tctttttttc
    17461 agaatcaaat agaaatttga gtttaacttt gctttgattt attgctgtaa gcttgtagtc
    17521 tacgtatcct gtttcaattt tttggggata aaaaatgctc tcttcttctg tcaaacctac
    17581 gcttcctaag aaatagccaa accactgatt gccgactgga cgataggttc cctgatcctt
    17641 tgtctgtgag ccactaattg tcttgctgac atttcgtgct gtacggacag cgttatttac
    17701 tagagaaaca tacatttttt catttgttgg acgaaaagtt acttggatcg catcgccaat
    17761 cgcataaacg tctttttgag acgtttgcaa gtagtcatct acccagatcg ttccatcatc
    17821 attcaatgtt aattgttctt cccacatctg attgtcgggg cgagaatgat tagccagcaa
    17881 aacaagatca tagttctcct ttcttttttc cgtctctaca atagcggttt cattttcggt
    17941 caaagacaca acttgttctt ctaaaaaaag tgaaagccct tgatttttca tttcctttac
    18001 taacggttct gtcatttcag gatctagata acgaaaaaga attgactttc ggctttcgta
    18061 aagatggatt tgtttttttc ttgatgccaa cccttcagct atttcgattc ctgcttgtcc
    18121 tgcaccaata attgcaattt tctttgcatt catgatcttt tgctgaagag ccgttacgtt
    18181 ttgtatcttt ttaactgggt gaataagcgt tgattctgca gaaatatttc gaaacttttg
    18241 atttgaacca gtcgctagaa tcaaacgatc aaaatccaat ttttttcctc ctgctaaaac
    18301 gacttttttt tctttcaatc ctattactgt cttttctgtg taaacatgga ttcgatagcg
    18361 gtcagtcagt tcttctttcg tgatccaaga aagttgtttt tcactggtaa cctttccttt
    18421 taatatcaaa ttgaacccgc tgggaatcca tcctaacttc gattgctttt caatcaaata
    18481 tatttcactt gttggcatca attggcgaag ataaatagcc gcatgaatcc ctgcaaacga
    18541 cccgccgaca attacaatgt tcatctgcat tcctctttct tataaggtgt tctactgcta
    18601 acttctcaat cagaaaacac agtattcata actcgctttc aaccttatga tacatagcga
    18661 tgcagcagaa tcaaccctct ccatcatacc gtgttctagg tctgcttctc aataatgtac
    18721 tagtggacct aattgaagag tatcatttct gaagagatgt ttcaaaaaat gtactcttat
    18781 aaaagaaaaa aactcgcctt ttacgtacct ctgtccaaat aggaaacaga aaagaacgaa
    18841 aagacgagtt ttagcgtgtg taatgtaata gttagaatag acacatcatt tatttttaat
    18901 tctttaatgc ttcaacaact gcttcgccta attgatgagc agattgagga ttttgccctg
    18961 taagaagccg cccatcaatt tgaaccactt ctgaaaaagc tgctccagac tgatagtttg
    19021 ctcctttttc tttcaaagca tcttctgcta agaatggtac ttcattcgtt gtaccatttg
    19081 cttcctcttc ttcattactg aacccagtca ctgtacgtcc agctaaaata gattttccag
    19141 actcatctgt aactggcaac aatcctacaa caccgtgaca aacagctgag accagccctt
    19201 catttcgata gatttgtgaa gcgactttcc caagatctat tgcttctgga aaatcccaca
    19261 ttgttccgtg gccaccagca taataaaccg ctgcataatc atttgcatcc acatcatcag
    19321 gacgtaaggt atttcccaag gcccgatttc tgaaatcttc atcttcataa taggcccaat
    19381 cgatttcatc catattcaaa acactttgcg gttctaaagg tacatatccg cctttaggac
    19441 tgacaaaatc tgcatcgatc ccatttttta ctaatacatc ataaaaatga gtcagttcac
    19501 ttaaccacaa acctgtagga cgctcgatct tttcgtactt ttctacattt gttaatacga
    19561 tcaatacttt cattttccca tcctctttct ataaaaattg cgttattgat aacgtgcttt
    19621 caagaaatta tataatgggc ttggcaaata aagctcttta tatgcttctt caaaaggttt
    19681 cgttacaaat tcatcctcac ggttttccaa taatttctct gcccagtcag gatcgacgat
    19741 catttgctgt ccaattgctg caagttctgc atatttcaat acctgctcta catcttcgcg
    19801 attgcggatc ccaccgacac caactaaagg gatctttcct tgaatcgtgt tatggaccac
    19861 ttcaagaatc gatttatcgt tgtatttatc agaacgagct attcgatcat acatatttaa
    19921 tgaaacatgc agataatcta gttttgactc acgtaatcgt tcaagaagcc agatcgtgtc
    19981 ttcaaaacgg atacctggtg tttcatattc ttctggtgag aaacgatacc ctacgatgaa
    20041 tggtttttta gcatattgtt caaccgctga gaaaaccgtt gttaataatt cttcaataaa
    20101 acgataacga ttttccaagc taccgcccca ttgatcctct cgtctattcg aatgcggaga
    20161 gaaaaattgt tggatcaaat acgtatttgc tccatgcaac tcgattccat caaatcctga
    20221 ttcaatcgct ctacgtgtgg ctttgccaaa tgcttggatt gtttcaacga tttcttcttc
    20281 actcattgct cgtggtgttt ccgcatcagg acgttttgct gcaactgcac ttgcagatac
    20341 aggctgttct ccagataaag ttgctcgact tgtcattcgt ccaccgtgga aaatctgaat
    20401 aatcgctttt gcgccttctc cttggattgc tttcgctagc tcacttaatc gaggaatcat
    20461 ttcatcatga gcgatgctga gttcacctgg ccagcctttt ccgatatctt ggacatttgc
    20521 agcaccagta ataacagcac caagaccttt agaacgttgt ttataataag tgatctcatc
    20581 ttcggtgatc actccattga aaaagctgag ttgtgtcgtc ataggcgaca gcatcaatcg
    20641 gttcttcaat tgaactcctg aaggtaaagt aattgattga tcaaattgtg acattgtcat
    20701 tcctcccata attcgctctg attaacctat cgagaatcat ctatcattaa accactcgat
    20761 tagttgtaca tgcaactaat ttgcttaaaa aattttattt tttttgtaac ttatctgttg
    20821 catcattcat tgtctgggct aattctttac ttgcttcatt tcccaaaact gctttgtatg
    20881 actgatgaag ttcttcccag ctaccatcga cttccttagc aaattggcgt ccttgttctg
    20941 taagataaac taatgacaag cgaccttcgc taactgtttt gacgtatcct ttatattcta
    21001 atttttcaac aaaacgagca atcgttgatg gggcggaata gagcatttgt gcaatatctt
    21061 tttgtggtat tccatctttt tcttttaata tcaataaaat aaaaccataa gttggtgcca
    21121 gacctgtcct tctaaacgct tcatcagcta atttattcaa catgcgatct agctttttca
    21181 cgctaaagaa aagacattca tctaacgctt tttcaattgg cttttccatt tcatcccctc
    21241 cattggcgta catatcatag tatgattttt attttttgtc aaaaaacacg gaataatgtc
    21301 cgcctcctct gtctagattt gaaaaaaaga agtagccatc ttcaaagaat ttcggcttgt
    21361 tttcgacaaa actccttctg gaacaccgtg aatcagaggt tgtgaaaaag tcgtttagtt
    21421 ttgagtatga agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt
    21481 aataccgaaa aactggcttt tgaacaccgt ttatatcaga ggttgtgaaa aagccgtcct
    21541 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atattttgtc gttttttgag
    21601 ctaatgccga tggtcagctg attgtacacc gtttattgag aggtcgtgag cctgccgttg
    21661 aactccgagt cacaaggagc aatttcaaaa aacagcttct catgttttat gactatggtg
    21721 acttgtgatc gaggagttgg caggagaata ctgtttattc gtaaagaagg ggctgtgaca
    21781 agacttttgt cacagtccct tatttccttt tattatagga tttcgccatt tgattggatg
    21841 acttgtctgt accaatcaaa tgattttttc tttaaccgtt tctttgtgcc attcccttcg
    21901 tcatcttgat caacatagat atatccataa cgttttgaca tttgtgaagt agaagcgctg
    21961 acgatatcaa tgcagcccca cgacgtataa ccaaataaat ctactccatc ttcgatagct
    22021 tccttcatct gctcaatatg ctgcttcaaa tagtcaatgc ggtaatcgtc ttgaacggtt
    22081 ccatcttctt ctactttgtc tatagctccg agtccgtttt cagctatgaa cagtggtttt
    22141 tgatacctat catataattg attcaaagca attctcaaac ccttaggatc aatctgccag
    22201 ccccattcac ttgatggaag atacggattt ttaattcctc cagttattaa gtttccttgg
    22261 accccttcca aattttctgg atgagcactg actgcactag acatgtagta gctaaaagaa
    22321 acaaaatcaa cagggtaggc tgctaagatt tcttcatcac ctacttctat ttttaagttg
    22381 acaccttttt cttcaaacat tcgttgcgta tacgctggat aatatcctct tgcttgaaca
    22441 tcactaaaga acaaagaagt tctttgctgc tcaattgttt tttgaatatc atccggatca
    22501 caagaatacg gaacaagaag ctgatagctg atcatacaac cgacttgtga acctttgata
    22561 atttcatgac aagcttttgt agctaaagca cttgctataa actgatggtg tgcaccttgg
    22621 tatttcgctt gttccaaatg gggatggttt tcttcaatta ctcctacgct aacaaaaggg
    22681 tgatgtttta cacagttgat ctcattgaaa gtcatccaat attttacttt atttttatag
    22741 cgtttgaata ctgtttcagc gaaacgaacg taaaactgaa taagctttcg attaggccat
    22801 ccaccatatt ctgtaaccaa atataacggc atttcataat gggaaagaga aacgactggc
    22861 tcaatcccat attttagaca ttcgtcaaac acttgatcat aaaaaaataa tcccgcttca
    22921 ttgggtgttt cttcatcacc atgaggaaaa attcttgtcc atgcgataga catccgatag
    22981 catttaaaac ccatttcagc aaataaacgg atgtcttctt taaagtgatg atagaaatca
    23041 tttccgtgtc ttttaggata ataatacttg ctgttgggat cctgcgccgc ttttacttgc
    23101 tgatgcgtca tcatatgcca ttgatctgtc catttttctt taggtaaatc gctgtcgaat
    23161 gtatacacat cagacacaga taatcctttt tcatctacat cccatgcacc ttcacattga
    23221 ttggccgctg tcgctccgcc ccataaaaat ccttctggaa attttttcat atcgatcccc
    23281 ctaaacttgc tagttttctt gtttgattat ttttcttatg actagtaatg atatttttga
    23341 atctactact atttgtaaca ataaccattg tggtcggatc atatccctct ttgattaatt
    23401 cttgcaaatc tacttccatc aataaatcgc ctttacgtac tttttttcca tcagatactg
    23461 cactttgaaa gtatttgcca tttaaattca ctgtatcaat accgatatgg atcagtatct
    23521 ctgctccttc ttcactgact accccaattg catgtttcgt tggaaaaact gttgaaactt
    23581 ccccgtttac aggactgtag atttttccgt ccgttggaat gatcgcaaac ccttctccta
    23641 aagatccact agcaaatgtt ggatcgttta cttcagataa atcaattatt tcacctgctg
    23701 caggagtact taacactata tcctttgagg attcttcttc gatttcatcc ttgtagccga
    23761 aaagaaaagt tagcatacag gaactgatca tcgctaagaa ataactagca actagccaaa
    23821 caaatccttc accaatataa atcgggaaag acaaaatact tcttgtagca actgccaaag
    23881 caccggctcc tgcggcacca gctactccac caaatatagc tccacatata caagcaatgt
    23941 aaaatggtcg tttatattta agagtcacac cataaacagc aggttcagtg attccaaata
    24001 atgctgtgat aaatgcagat aaagataaac tttttacttt cttatttttc gttttcaaaa
    24061 ataccccaag tactgctcct gcttgcgcag ctacggcagt catacatgct ggacctagcg
    24121 tatcacgacc gtagaaagaa agattgttgg tcattactgg tacaagtccc caatgtaacc
    24181 caaaaatcac taacacttgc caaaatccgc cgataacagc accagataaa acagggctaa
    24241 agttataaac agctaaatat ccagctgcaa tcagctgact tgcataatct gcaattggac
    24301 ctacaactaa taaagtaatt gggaccatca cgatgataca aatgaatggt gtcaataaat
    24361 ttcgaatact ttcgtgcaag cttttgcgaa tcttaggctc aatataagaa agaacccata
    24421 cagctaaaat tgctggaata accgtacttg tatatcttgc tagaatcacg ggcatcccta
    24481 gaaatcgcaa ggttatgcta tcactatatg cactgacaat cgtaggataa acgagagctg
    24541 ctgcaataac catagcgatg aaacgatctg tattgaactt ttttgcagca gtatatgcca
    24601 aaaatatagg caagaaatag aaaaatgcat cagctgctgc attcaaaatg atataagttc
    24661 ctgattcagt agttaataaa ttcaaactcg tacataaggc gagtactcct ttgatcaaac
    24721 cacttcctgc caagacgcct aaagtcgggg caaaaacagc ggcgatcatg tctataaaag
    24781 agtttaaaat gccttttttc tcagttcctc tctttccact agatgcatca tcttctagtt
    24841 tcatttgttt ggataatacg tcatacactt catttactgc atttcctact acgacttgaa
    24901 acattcctcc agcttcgact acagtgatca caccttctag ttgctctacc ttctccttat
    24961 ctgccttctt attatctttt agggtaaagc gtaaccttgt tgcacaatgg taaacattgc
    25021 tgacattttc ttcgcctccg acaaatcgga caatatcttt cgctaattgt gaatagtcca
    25081 tttttacttc ccccttgtta attaatgccg tagcaatcct tcttacaaga taagtatagt
    25141 tcttagaaaa cggtttctcc attcaattag taccccttct aatagcgaac gaaactgtac
    25201 aatagtgtgt atggtttact tagccgagca aatcactcac tgcttgaaag aaaacaagta
    25261 tatcgtttct cttatagtca aaggagacaa aaaaaacacg cttgatcttc ctttgctgat
    25321 gtataagtgg tatctcaagc tgatactctg tgatttttgt ttctacttgg cttttgataa
    25381 gacagcacaa caaagtctcg gcatttaacg gaagcataac taggtcagaa ctaggagaga
    25441 ttagttgctg aatggaatct atctttttat ggatttttat ttgattttct tctttgtagt
    25501 aatgatcaag cagttttgtt ttcttttttt cttcaactat ggtcagcttt tcacgcaaaa
    25561 tctgataaat ctccgaagat tcaaactcat ctagaacact aggtagataa atcaaatcat
    25621 cccactcaaa aataagctct tgctcagtag tcaaaattgc atcatattcc gttattttgt
    25681 ttgattgatt tttgaaaaga tacactggtt ctatccggca ttctttgatc cacatgttca
    25741 tactttgttg aatctgtttt tttagtgtat tcaaaatact aattggctgg ttactaacaa
    25801 tcagtatctc cccttgtttt cgaaaaggat tcaacgcttc ggcaagatac aaaaccaaat
    25861 aagcgctttc agctaaattg ggacgtaatt gaaaatgtat tgggaagaaa cgccgaatta
    25921 aataaatttc taaaggataa cgggagatga tcttttgtac aaaatgattc atggtattat
    25981 gtccggcatc catcctcgtt ttcatttgtt tgatatgggt tagcaaaaat tctgtttcat
    26041 ggaacaataa cgaaacagga agatctaaaa aacgaataat cgtttgctca aatgctctta
    26101 gattcttctc tatttctttg tttttttcat cattaatcat caaataattt aactctaata
    26161 gtcgattttc aattgcttgt ttttcttgat tggaaaaaga atagggtagt tctgatgata
    26221 acttttttgt gagggtctct accatcggaa taaataatgt atacctgttt gttttttcta
    26281 aaagttcttc tcttcgaaga atggtcaaaa cgagataccg agaaaatcgt atgaagtcct
    26341 ctcctgaaac aatataatta tatgatataa gaacctcttt taatgtcttt tggacagtcg
    26401 gcatgatatt ggaaaaaatt gtactgattt gttgaggcaa ccttgcgtgt tggatcaccg
    26461 tttctgttcc aacaagagat aagaaaattc tttttgaatt ttcttcagca atgattttta
    26521 gtccttttgt cgacgaaact tccagttcta atttaggatt gcgctcgatc caacgcaaaa
    26581 tcgtttttat ttgtaatgat acggctgttt ttgaaagaaa gaaaatgtct gctatctttt
    26641 gcatactgac ataccctttt tgaaacaata agtacgtcac aatagttgaa gctcggaaat
    26701 ccatgctgga atagatttta tgtttcgtca cctcttgtat gatttgctgt ttagtttcag
    26761 attcaattga ttctaaaaaa taacctgaac gtttatttga ctggataatg attttcttct
    26821 cgtagatagc aagcatattt ttgatttcag tttggatcgt tttcttgttg gtacctaaag
    26881 cttcagctaa ttcttcgctt gttatccaat gattcttatt tcttaatact acaagaattt
    26941 ggagttgtcg tttatttaag tccatttgct tacacctcct ctttgttata aacatacagg
    27001 aaaaacctct caaatgacaa tagtcacttg cagaggttta aaaatcattt gaagaaagat
    27061 ctatattcaa ggtttttacc attagactgg ataatttgtt tataatattc aaaactatct
    27121 tttttcaatc tcctaaagct tccgctccca tcattttgtc tatccacata aataaagcca
    27181 tatcgcttcc tcatttcccc tgttcctgcc gatacgatat cgattggtcc ccaccataag
    27241 taaccaatga tttggcaacc atcttttatt gcctcagcaa tttcctgaag atgtattttt
    27301 agatactcac aacgttttgg atcgtggatt cgattcaatt catctggtgc ttcatctagt
    27361 ccaatgccat tttcaactat gaataatggt aattcataac ggtctgtcaa ttcattcatg
    27421 acataacgaa accctagagg atcaattggc caactccaag gttcgggaga tttttccttc
    27481 aaaaagggat tatcgaaacc atttgctccg ccagtatcta cgcgcatttc tgcttctttt
    27541 ttatagacag cgctacgata ataactaaat gcaatataat ctaccgtgtt agcttgcaag
    27601 tactgttcgt ctccatctaa cattactggt gcacagtctt cttccttcca tatcctgtaa
    27661 atataagctg gataatgccc tcggcacatg acatcggaga aaaaccatga attgcgttta
    27721 aattgcagtg aaccaaatac attctctgga tcacagtcat atgcataagt cgctaatgca
    27781 gaaaagctac acataatacc catcttagca tttggatcga ttttctttaa taattgagta
    27841 gcacgggcgt tcgctagaaa catatgatga caggcttgat aaatctcttt ttttgttagt
    27901 gtagcaatgg gttcaagttt atctctagca gggaatgtaa ccaatccagc agctgcataa
    27961 ggcatacgaa aagcattatt gatctcatta aaggtcatcc aatatttcac tttcccttgg
    28021 tagcgttcaa agacggtctg cgcataaaat tcaaaaaagt cgattaattt tcgattttgc
    28081 caccccccat actctcctac caatgctaag ggggtttcat aatgactaag agtaattact
    28141 ggctcgatat catatcgatt taatgtattg attagtctgt cataaaatac gagaccagcc
    28201 tcatttggct tctgttcgtc tcctcttgga aatattcgtg cccatgagat gcttgttcga
    28261 aaagctttta aacctaactc cttcagtaaa cgaatatcct cttcaaatcg atgataaaaa
    28321 tcaatcgctt catgagaaag ataatggagt gattcgtcta aagcaatctc ccaaatcttt
    28381 ttttcttcat tccactgaat actaggatgc tggttcatga tcccgataag cgtatctgtc
    28441 acattaggta atttgccgtc ttccaaccat gcaccttcac attgattagc agctactgct
    28501 ccgccccata aaaaattttc tggaaatatt tcctgatcca taactatctc tcctcgctat
    28561 caacaatttc ttacttgaag tatagctcga ttcatcaaaa caagatattc taactatttc
    28621 ggcagaagag aagaaaaaaa ttgaatgcta ctcttcattt ttaatattta tatataacaa
    28681 atacataaga cgatccccga aagaaaacac tcgttaacca tctaagcaaa cgatttattt
    28741 tacttccaac acaaatgctt cataaggtcg taaatcaact ttgccgtctg gtaactgttt
    28801 cagaggataa tttgacacaa taacccttaa agcttcacgt ggaacagtga acgtctgctt
    28861 ttcactggac atattacaaa taacgagcca ttgctggtct tcatatatgc gagaataggc
    28921 aaagacatgc tcaggcgtct tttccactaa ttcatagtct ccccagacga tgatgtcatg
    28981 ttttctacgc aaatcgatca atttcttgta catataaaaa acagaatctt gatctgctaa
    29041 cgcttcttct gcattgattt ctttataatt tggattgact cgaagccatg gaattccagt
    29101 agtaaaccca gcatgttcac gggcgttcca ttgcataggc gtcctagcat tgtctcttcc
    29161 tttcgcattg attgattcca agatttcctc ttttgtaaat ccagaagaaa tcctttcgtt
    29221 atacatattg attgtctcaa tatcttttgc ttccgcgata tcatcgattg ggcaattcgt
    29281 catgcctaac tcttctcctt gatagatata aggggtgcct ttcatcatat ggagcaagat
    29341 agcaaacatc ttggcacttt cttttcgata cacatcgtca tttccccaac gagaaacaat
    29401 tcgcggaaga tcgtgattat tccaaaataa actattccat ccttcatcac ctaaagatgt
    29461 ttgccatttg gataatactt ttttcagttc agagatactc aagggtttca aatcccattt
    29521 gtctttgcct tcttgctgat ctaatcctat gtgttcgaat tggaagacca tggataattc
    29581 atttctttta ggattggaat aaagtttagc gatttcggta gttgctcccc atgtttcgcc
    29641 aacagtcatc agatttttgt caccaaaagt tgcttgattc atttcctgaa gatactcatg
    29701 cagtttaggt ccattacttg tgatttcttt atccggttct ttgccaatca tatcgatcac
    29761 gtccatacga aagccaccaa tacctttatc gatccagaaa ttcatcattt gataaatctc
    29821 ttggcgaacc tgtttatttt tccaattcaa atcaggttga cgcttgctat acaagtgcag
    29881 aaaatattgc cccgtttttt catccaactg ccaagcagaa ccactgaata ttgagcgcaa
    29941 tctattaggc tcttttccat tgaccggatc acgccaaata taatagtccc gataaggatt
    30001 ttctttattt ttacgggcct caatgaacca cggatgttca tcagaagtat gattcaccac
    30061 cagatccatg atgatacgga tatttctttt ctttgcttct tcaatcagtt cttccatttc
    30121 ttccatcgta ccgaattctg ccatgattgc ttgataatta ctgatatcat acccattgtc
    30181 atcattcgga gactcgtata ctggagaaag ccaaattgca tcaataccta aatacgccag
    30241 ataatccaac ctggaaataa tcccccgcaa atctccaata ccatcttgat ttgaatcttg
    30301 aaaacttctt ggatagattt gataaacaac tgaatggtgc caccattttt gttccatgat
    30361 tttcctccta taaatggatg tttctatttt ttgcttaatc atttatttta gtctctctca
    30421 ctaaaaattg taacgctttc aaatagctat tgcaccttgt tatcggtaac agaataaaac
    30481 aaaaaaacag ctgaggaaat tccctcaact gttttttgaa aggattgatt tattcaggga
    30541 agaatgctga tttcacaact tctttataaa cggtgttcac tcagctgtcc ctcggtatta
    30601 gctcaaaaaa cggcaaaata taagaaacta tttttttcgt ttttttctct aatactcagg
    30661 ccagaacact gatttcacaa cctctttata aacggtgttc actcagctgt cccttggtat
    30721 tagctcaaaa aacggcaaaa tatgaggaac tattttttcg tttttttctc taatactcag
    30781 gccagaacac tgatttcaca acctctttat ttcacattca atatccacat gaatcccatg
    30841 aatacaaaga acagaccata catgatggga gatacttctt ttcctctttt agctgctaac
    30901 atggtaattg gatagaagat aaaacctaat gcaatcccat ctgaaatact ataagtcaaa
    30961 ggcatgccga tcaagatcaa gaatgaaggg atcgcaatct ctaagtttcc ccattcgatt
    31021 tgtcgcaaag attgtgccat caatactcct accataatca atgctggtgc agttacttgt
    31081 gaagtaacaa ctgatagtaa tggagaaaag aacaagccta acaagaagaa aatccctgta
    31141 gtaatagctg tgatacctga acgtcctcca acggcgatac cagctgatga ttctacaaat
    31201 gcaccaacag gagaagtacc taataaggaa cccgcaagca tagctgttga atcagaagct
    31261 aaagctttcc ctacacgagg catcttgttg tctttcatga aacctgcttg gtttgctaat
    31321 ccaactaaag ttcctgctgt atcaaagaaa gtcacaagca agaatgtcag cactacgacc
    31381 cacatttgaa gagaattgat gtcccctaca tgttttaatg caactaaaaa tgttggtttc
    31441 aaacttggtg ctgcggcaac aatttcagaa ggcattggaa tcaaacctgt gaccagacct
    31501 aaaatcgttg tagctgccat cccgatgaag atgccacctg gtacacgccg aacaagcaag
    31561 atagcagtta cgactaatcc aaaaatcgtc aaccaagtag aaccaacgtt gagtgatcct
    31621 aatcctacta atgtagattc attcgaaacg atgatcccac cttcgctcag accaaggaaa
    31681 gcaataaata gaccgatacc gccagaaatc gcatatttca aatctgctgg gatcgcatca
    31741 atgatcattt cccgcagctt gaagattgtg atcaaaataa aaatcaaaga agcaacgaat
    31801 acgccggcta atgctgtttc ccatggaatc cccattccta aacaaacaga ataagcaaaa
    31861 aaagcattga tcccaagagc aggtgccgtt ccaattggat aacgggctaa tacccccatt
    31921 aaaatacagc cgatcgcact ggctaatgca gtcgcagtaa acactgctcc ttcatccatt
    31981 ccagaagcac ctaatacagt tggatttaca aataagatat aagccattga gataaatgtt
    32041 gtaaatcctg ccagtacctc acgttttacc gtggtgttca atttttctat ttcgaagtag
    32101 gaaagtattt tttccttcat cttccatccc cctaaatccg aacattataa ataaagtccg
    32161 ttaaaatttc gatttattaa taaaacaacg tgttttatca tatactaaaa caaaacataa
    32221 gtaaacaaaa aattcggatt ttaagcaaaa tccgaacgtt ccatctgatt aaatcccttt
    32281 atctcaaagt tcatgaacat tcactttgga ttacaagaat ttctttattg tgttaataaa
    32341 gtttcttcat tctagtctca aaaatcaata gtgtgatttg attttaccat ttcgtttctg
    32401 ttcttctttg atgaattctt ttgtatcgac aggattcaga ttatttagtc cgccaaaacc
    32461 tgtatcgacc atttttcccc agccttttgt cttctttttt cctgatttga gattctttgc
    32521 tcgaagcttc tcactatgtt ttgctcgccg atacttcaaa taaccttcta atcttcccat
    32581 tagatccact gtttctcctc ctttttattc aatcagacga ctcagctttt cctataacaa
    32641 aataattgcc ttcagggtcc gaaaaattga aagtcaagac gccattgttg tctgtgattt
    32701 ctcctggttc ttccatgttc tcgtagatag tttcaaattc atccgtaaaa aatactaaag
    32761 aaggcggtgg tcctaatacc tctggtgaaa acttctgcac aaatactttt gggaatacgc
    32821 ctaattctaa ttcttttgag atgctgagta caatactctt aaattcttct ggcaattcga
    32881 ttgtttcaga aatttctgca ccaatttttt ctacaaagaa tcggcaaatc atctctacgt
    32941 cattgacata aagcatcaca cgtgtttttt gtatcatcgt ttgacccttc tttctatttg
    33001 attttctttc ctgtctataa actgattcca ttatatcacg aaagcgcaaa caccttgtgt
    33061 ttgatactat tcaagaaaaa taaagcaata gtttctagga ttgctttcct ccacaaactt
    33121 ttttta
//
LOCUS       DAXLPC010000025        32535 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.025, whole genome shotgun sequence.
ACCESSION   DAXLPC010000025 DAXLPC010000000
VERSION     DAXLPC010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.025"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            133..507
                     /locus_tag="ACF3UE_001107"
     CDS             133..507
                     /locus_tag="ACF3UE_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFD3634556.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(621..1250)
                     /locus_tag="ACF3UE_001108"
     CDS             complement(621..1250)
                     /locus_tag="ACF3UE_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFD3634557.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1384..1456)
                     /locus_tag="ACF3UE_001109"
     tRNA            complement(1384..1456)
                     /locus_tag="ACF3UE_001109"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1421..1423),aa:Thr,seq:ggt)
     gene            1670..1743
                     /locus_tag="ACF3UE_001110"
     tRNA            1670..1743
                     /locus_tag="ACF3UE_001110"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1704..1706,aa:Asn,seq:gtt)
     gene            complement(1881..2045)
                     /locus_tag="ACF3UE_001111"
     CDS             complement(1881..2045)
                     /locus_tag="ACF3UE_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634558.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2340..3668
                     /locus_tag="ACF3UE_001112"
     CDS             2340..3668
                     /locus_tag="ACF3UE_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFD3634559.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3870..4703
                     /locus_tag="ACF3UE_001113"
     CDS             3870..4703
                     /locus_tag="ACF3UE_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFD3634560.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4719..5456
                     /locus_tag="ACF3UE_001114"
     CDS             4719..5456
                     /locus_tag="ACF3UE_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFD3634561.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5611..6579)
                     /locus_tag="ACF3UE_001115"
     CDS             complement(5611..6579)
                     /locus_tag="ACF3UE_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFD3634562.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6811..7644
                     /locus_tag="ACF3UE_001116"
     CDS             6811..7644
                     /locus_tag="ACF3UE_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFD3634563.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7678..8517
                     /locus_tag="ACF3UE_001117"
     CDS             7678..8517
                     /locus_tag="ACF3UE_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3634564.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8543..9103
                     /locus_tag="ACF3UE_001118"
     CDS             8543..9103
                     /locus_tag="ACF3UE_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3634565.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9302..11023
                     /locus_tag="ACF3UE_001119"
     CDS             9302..11023
                     /locus_tag="ACF3UE_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFD3634566.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11188..12330
                     /locus_tag="ACF3UE_001120"
     CDS             11188..12330
                     /locus_tag="ACF3UE_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFD3634567.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12346..13557
                     /gene="thiI"
                     /locus_tag="ACF3UE_001121"
     CDS             12346..13557
                     /gene="thiI"
                     /locus_tag="ACF3UE_001121"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFD3634568.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14130..14777
                     /locus_tag="ACF3UE_001122"
     CDS             14130..14777
                     /locus_tag="ACF3UE_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFD3634569.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14906..15122
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15170..17815
                     /locus_tag="ACF3UE_001123"
     CDS             15170..17815
                     /locus_tag="ACF3UE_001123"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFD3634570.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18125..19438
                     /locus_tag="ACF3UE_001124"
     CDS             18125..19438
                     /locus_tag="ACF3UE_001124"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFD3634571.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19428..20081
                     /locus_tag="ACF3UE_001125"
     CDS             19428..20081
                     /locus_tag="ACF3UE_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3634572.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20136..20828
                     /gene="radC"
                     /locus_tag="ACF3UE_001126"
     CDS             20136..20828
                     /gene="radC"
                     /locus_tag="ACF3UE_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFD3634573.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20978..21178
                     /locus_tag="ACF3UE_001127"
     CDS             20978..21178
                     /locus_tag="ACF3UE_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3634574.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21432..23111)
                     /locus_tag="ACF3UE_001128"
     CDS             complement(21432..23111)
                     /locus_tag="ACF3UE_001128"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFD3634575.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23113..23325)
                     /locus_tag="ACF3UE_001129"
     CDS             complement(23113..23325)
                     /locus_tag="ACF3UE_001129"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFD3634576.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23718..25448
                     /gene="efrA"
                     /locus_tag="ACF3UE_001130"
     CDS             23718..25448
                     /gene="efrA"
                     /locus_tag="ACF3UE_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFD3634577.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25445..27205
                     /gene="efrB"
                     /locus_tag="ACF3UE_001131"
     CDS             25445..27205
                     /gene="efrB"
                     /locus_tag="ACF3UE_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFD3634578.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27300..27497
                     /locus_tag="ACF3UE_001132"
     CDS             27300..27497
                     /locus_tag="ACF3UE_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634579.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27650..28135
                     /locus_tag="ACF3UE_001133"
     CDS             27650..28135
                     /locus_tag="ACF3UE_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFD3634580.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28239..28832)
                     /gene="clpP"
                     /locus_tag="ACF3UE_001134"
     CDS             complement(28239..28832)
                     /gene="clpP"
                     /locus_tag="ACF3UE_001134"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFD3634581.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29012..29533
                     /locus_tag="ACF3UE_001135"
     CDS             29012..29533
                     /locus_tag="ACF3UE_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634582.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDV"
     gene            29630..30367
                     /locus_tag="ACF3UE_001136"
     CDS             29630..30367
                     /locus_tag="ACF3UE_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFD3634583.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30371..31288
                     /gene="miaA"
                     /locus_tag="ACF3UE_001137"
     CDS             30371..31288
                     /gene="miaA"
                     /locus_tag="ACF3UE_001137"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFD3634584.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31290..32519
                     /gene="hflX"
                     /locus_tag="ACF3UE_001138"
     CDS             31290..32519
                     /gene="hflX"
                     /locus_tag="ACF3UE_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFD3634585.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVNRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEIAVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10772 a         5522 c         6875 g         9366 t
ORIGIN      
        1 gtctacactc tgagatgtaa gaaatatcat aagatatttc ttacatcttt ttgttttgag
       61 caggacttta gataatttta ttaatatatg ctagcatgct tttgtaagaa aaagaaagag
      121 ggcgtattag ttatgtatct taaaattacg gaacaagcac aagaaagatt acaaaaatat
      181 attgatgaag gcgcaacagt tatattggat ttagatgatg gcgttgggga atattctaaa
      241 atgggtgttt gctctttaga tactagtttt cgtttacttc ttcttgataa agaacagaga
      301 aaaaatgatt ataaactcca attagatagt gatattgggg atgtttatat aaaagattat
      361 tcaaaaatgt acatggatga acatatgacc ctttctttag atccacgtct aggtgtattt
      421 actcttgaaa gcccaagtgg ttctttagac agtcatgttc aattagtaga tctacgacca
      481 gaaaaattct ctggaataaa acaataactt tctctctatt gtccataaaa ctagtctcaa
      541 tcaagctgta ttgaaaaaac aagacaacat tcttaccatg gtaaataaaa agacgacaca
      601 ttttgtcgtc tttttttaaa ttaactattt tcgataaaag atcgcatagc ttgtgccatt
      661 atttctggct tttctctatt caattcatgt tttccgtttt taataaagag tagccggcca
      721 ttcgttgaaa gtttatataa acgttttgct gctggtttat tcgcatgatc tttggtaccg
      781 cataaaatca atttaggaag tcgtgatgta cgaagctgtt ttttgcagtc taatgtttca
      841 agtgaacgaa gtagggtaag ggtttgtttt ttagatagac ctaatttttc aaatatctta
      901 gaaggtacgc agtaaaaata aatattctgg aaagtaagca ataagcgatt aggagactca
      961 aattgtggag cgactaaaac aacctttttt aaatatggag aaggagttgc aagatagttt
     1021 aaagcaataa cagcgcctaa agataatcca cataaaataa aaggttcctt tatctgattc
     1081 aattgtactt cgatgtattt ggttaagtcg tctaaagtag cagtgtctgt gctgtttaaa
     1141 tgattgaaca atgaaagact tttgcaagaa taactattgg gtagataaga gattacatct
     1201 ttccatgatt gttcgtcttg gcctagacca tgcaaaaaaa caattttcat attgctctcc
     1261 tttttatagt tatcatatag actttctttg tactattaaa atataaacat tcatttctta
     1321 cgtcataaaa taaaaaaaca gcgcagacac attgttaaac caacatgttg cactgtttaa
     1381 ggaagccact tgccgggctt gaaccggcga cctcttcctt accatggaag cgctctacca
     1441 gctgagctaa agcggcatta tcattaatac aaataatagg ataacgaata ttaatgtatt
     1501 tgtcaacaga attttttcga aaaaatgtgt ttctctaata ggaaaacaga ttttagaaaa
     1561 aataaaaata acaaaaaatg cgaacggttt ctttgataat ataataaaaa aattcaaaaa
     1621 aagtattgcg ttatttagaa gaaattgata ttatattcat gtacttgatt ccggcatagc
     1681 tcagttggta gtagcgcatg actgttaatc atgatgtcgt aggttcgagt cctactgccg
     1741 gagtaaataa agcttatgca aagaaaaaga aatccaatca cttgggtttc tttttctttt
     1801 attattatga tgaatcaagc tttctgtttt tgtcacgtat gttgtaatct ttacgaaaga
     1861 gtagagttgg ctactcataa tcaaccatac ttcccatcat cgctaaatac gaaataaatc
     1921 agcattccta caccaatcaa agcacaagct gcaccaagaa aagggatgac attcccaaag
     1981 ttatctgtat tcataagtat gccaccaccc acaaacaaaa agccgccagc aatcaggttt
     2041 ttcattttat tcatctcctt tcttacgtta tagtatttcc ttctttcaat gagtattttg
     2101 aaagctatct tattgtatga tgttcttcta ggcctcttct ttattataca ggccattttc
     2161 gttatctcat agaaatattc ctttttatct gaaaactatt gtataccgta tgacattttt
     2221 cttcatgaag ttgtaagtat attctcattc aaatgaaaat ttcatcatag aagagattgt
     2281 atttctaaat tcttaagagt aaaatacgaa gtataacttg gatttggaag gatgattgga
     2341 tgaaagctat tacgcctgat atgacaacaa aatttaacaa acagtttcaa gcaaatatca
     2401 aacagcaggc attgcagcgg gcagttgtga agaacggaat tactgcttct gctgaaaatg
     2461 tttcagcaca tgtggagaat acaccggtat tttctataga tttggctacg gggaaagtgg
     2521 ctaatcaaat gcaatcgggg cgttgctgga tgtttgctgc actgaacaca ttccgtcata
     2581 agatgctgaa tcaattccat ttaaaagagt ttgaattatc acaaaattac acttttttct
     2641 gggataaata tgaaaaggca aattatttct atgaaaacat cattgcaaca ggaaaagagg
     2701 caatcgatag ccggaaagta gctttcttac tcgctactcc tcaacaagat ggcggccaat
     2761 gggatatgat cgtttcatta ttccaaaaat atggcgttgt gcctaaatcg gtgatgccgg
     2821 aaagtgcgaa tagttcaaat tctcgagatt tgaataacta cttgaacaaa ttactgcgta
     2881 aagatgcagt agtgttacgg aaaatggttg ctcaaggaga aacattagac gctattgaag
     2941 aaaagaaaga agaaatgcta gaaagcattt ataacttctt agctatctca ttaggaacac
     3001 ctccaaaaga attcgatttt gagtaccgcg atgaagaaaa gaactatcat cttgaccgag
     3061 gactgacacc acaaattttt tatgataaat acatcggtgt aaaattagat gattatgtta
     3121 gcgtgatcaa tgcaccaaca aaagacaaac cattcaatcg ttcttataca gtagagatgc
     3181 taggaaatgt cgttggcggg aaagaagtca aatatctgaa tgttgatatg gaaactttca
     3241 aaaaattagc gattgctcag cttgaagaag gagaatctgt ttggtttggt tgtgatgtag
     3301 gtcaatcttc tactagaact agtggcatca tggccttaga tgcttattca atggatgatc
     3361 tatttgatac ggattttaca atgactaaag ctgaacgttt agattttgga gaaagtctga
     3421 tgacccatgc gatggtattg accggtgttg acttagtaga cgggcaatca acaaaatgga
     3481 aagtcgaaaa tagctggggc gaaaaagttg gaaagaatgg cttctttgtt atgagtgatg
     3541 cctggatgga cgaatatacg taccaaatcg ttgtaagaaa agatttattg acgaaagagc
     3601 aattaaatgc gttcaatgaa gaaccaattg ttctatctcc gtgggatcca atgggtgctt
     3661 tagcatagac gagtatttca atgaagagta tgtagtaaag ataaaaagag ctggcttaag
     3721 ccagctcttt ttatctttaa agtccattcc ctgtttttta tggtccctgt gctataattc
     3781 taaataaagg ataaggattg gaaataatcc ttttatcatt aaaaatatga tgacgaagta
     3841 gaataaaatt gggagtaggg gggaaagtca tggatatcca aactgtttta tctgatctga
     3901 aattaaatgg taaagtgatt ccagttgttg gtggcgatgt taatcagacc tatcgtataa
     3961 aaaccgaaca tcgtgcttat tttttaaaaa tccatccgaa tgtaaaaaaa ggattttttg
     4021 aagcagaagt agacggatta aaagaactgt cagcattcgt acgtgtaccg gatacgtata
     4081 tgctaggtga aacaagtgaa ggcgcttatt tgttaatgga atggatcgag ccgggaaaag
     4141 gggatcaacg agatcttgct gcagctttag ctaatctcca tcagcaaaca gcgccacaat
     4201 ttggttttcg taaagataac tatttgggta cacttgttca gaaaaattct tttgaagaag
     4261 attggtggac ttttttcttt aaagatcggc ttgaatccca gatttctttg gcagaagaaa
     4321 cgaatcgatg gaatgtacag cgtcaagaaa agtatctgcg atttaaagaa cgtgtattga
     4381 aatcggttga accaaaaaag atcactccac gcctcttgca cggagacctg tggagtggta
     4441 atgtgttctt tgaccagcaa gggcatccag tttttgtcga cccagctgtt tcttatggga
     4501 atcgggaaca agatattgca atgagccagt tattcggtgg tttccgaccg gaatttttag
     4561 atgcttatca aactatattt ccattagaaa agggatggaa agaccgactg ccgatttacc
     4621 agttatatta tcttttggca catttgaata tgtttggaga aagttacggt tcccaagtag
     4681 atcaattact agaaaatttt taagaggagg gcgtgttttt ggcaaaaaaa tataccaaaa
     4741 agcatgaagt ttcatattat gagtgtgaca tcaaccaaac gatgacattt ccttcgatgt
     4801 taggagtagt tatcaaaacg tctgaagatc aaagcgacca gttgggaaga ggcagtgaat
     4861 tcgtcaatag ctttggactt acttgggtca tcacgaatta ttccatggag attaatcgtc
     4921 tccctagagt cggtgaagta atctcagtaa cgactcaagc catggagtac aataagtttt
     4981 tctgttatcg gaacttctgg atccatgatg aagatgggaa agaattagtc aaaatagaat
     5041 ctgttttcgt attgatggat tttgtgaatc gaaaaatgag cagtgttaat gaagagatca
     5101 ttgctccttt tgagagtgag aagatcaaga aaatcaagcg tcaggaaaaa attgaaaaga
     5161 ttgattcggg cttcatgttg ccatatcgtg ttcgttttta tgatatcgat agtaatcagc
     5221 atgttaataa tgcgatgtat tttaattgga tcattgacgt attaggatat gactttttga
     5281 ctacgcatgt tccagaaaaa gtaattattc gatttgataa agaagtagag tacgggaatg
     5341 agatcgaaag ccattttgaa caaatcccta tcgaaaatgg tgtcaaaaca aaacatgaaa
     5401 tccgaatgca agaacagctg tattgtgaag caaatattat atggaaaaat aaataaaaaa
     5461 gaggttgtga cagaaggggg caacttcaag aaataagaag aaatttacga aaattgtttc
     5521 tcaaattttt gtaaattttc gacttagttt tcgaagaagc tatttttgtc acagcctctc
     5581 tttttaagtt tagctattag ataatgatgt ttagttttgg ataaacgaaa tcaattcttc
     5641 acccgacaaa ccatagttta cagcaatcaa tagttttaaa cgtgcttttt gactattaat
     5701 actgttacag aaaataatcc ccattttttc tagttctttt cccccgcctt cataatcata
     5761 aacaggctct gcgattccat tgaaacaacg agaaacaagt actacaggga ttttttggac
     5821 aagaagcttt tccaaagcag ctaaggcttg tggagggaga ttccccgcac ctaaagcttc
     5881 gattaccaaa ccgtctactt tcgtatgggc gatggcttcc aataagtccc cttgcatccc
     5941 agcatatgct ttaacgatcg ggatagtccc atctacagcg gaaatgtcca gtcgctttgt
     6001 ttctaaaagt tcctgcaaga ataaaattcg attcttagtt actaagccga tgggacccaa
     6061 tgtaggtgtt cggaaagtag caacatttgt ggtatgggtc tttgtcacgt agcgtgcaga
     6121 atggatctca tcgttcatga ccaccaaaac ccccttatct agcgcttctt cacaacttgc
     6181 gacacgaatc gcactttcaa aattataaag gccgtcactt ccaagttcat tacttgaacg
     6241 cattgcccca gtcaaaacaa ttggtaattt gttgccaatc gttgtatcaa gaaaaaaagc
     6301 agtttcttct aatgtatctg taccgtgtgt gatcaccact ccggatatac ctgatgcata
     6361 agcggacaag atacgttctt ttaataccaa catgtgagaa ggcatgatgt gtggtgaggg
     6421 aagattgaag atatcttcaa ctaataattc tacatgcttg gggattgtga tttctgcatc
     6481 taataatggg tttgccacat caggactaac accgcccgtg agcatgtttt ctttcatggc
     6541 gatcgttccg ccggtgtgta gtacaagtat ttttttcatt ttacagactt ccttacgaat
     6601 aattttgcat agccgttaaa tcttattgta tactatataa aagagttttg ctatcagtga
     6661 agaataacga atagcctaac ttatcataaa aaagctgacc ttattaaaat ggaaaagact
     6721 caaccttgac ctcctaatac aatggagtat ctggttgagt ttcttttaca agaaagcagc
     6781 caaggaaatc aatcacgaag gtggccggaa atgatcagaa tcggattaac atcgtttaaa
     6841 gaacatgaca aattaactgg taaaaagaat aacactcttt atgaatatgc agggtttcta
     6901 cccttagtgg aattagatac tgcctattat ggaattcccc gaaagtcctc agttgagaat
     6961 tggataagtg aagtacctga atcatttcgc tttgtagtca aagtctatca aggaatcagc
     7021 ggtcaaggag actggaagcc ttattatcag accgaagaag agatgattgc gcatttttta
     7081 gatgttatgt cgccaatggt agatgctgga aagatgtttt gctttttagt ccaattcccc
     7141 tcatcattca aatgtacgaa agaaaatgtc cagtacttgc gcaaacttag aaagtggttt
     7201 gagggttatc ctgtttctat agaattgcgg gattattctt ggtacagcga tgaatttctt
     7261 gaacgtacaa gaaactttat gtctagagcc gctttttctt tagccatcat cgatgagcca
     7321 cagttgctga atacaacgat tccttttgat ccatttgtca ccaatccgaa ctttgctctt
     7381 tttcgattcc atggtaggaa tgcgcaagga tggcaagcaa atgataaaga gtggcgtaaa
     7441 aaaagaacgt tatatcgtta ttcagaaaaa gaactgcaag aactagcaca tgaagtcaaa
     7501 gtagttgatt ctaagacaaa agaggtaggt gtgattttta ataataattc tggtggtgat
     7561 gcggctgaaa atgcattagc actgcaaaaa atattaaata tcaagccaga tggactcaat
     7621 ccaacccaaa tggatctgtt ttaagggctt attttattca agaaaggggc gaagtctatg
     7681 atcaaagcta ttttttttga tattgacgga acattggtca ccaatcgttc aaaagcgttg
     7741 gaatcaacaa aacaagcaat tgaatatgct cggaaaaacg gcattttatg cggtgtagca
     7801 acggggcgca gcccagtaaa gatcaaagaa atcattgatg aattggaatt agatatgtat
     7861 gtcgtgtata atggtcaact ggtttttact gcagatcgca cgattatcga ccaccctttt
     7921 gaacaaaaag tattggaaca tattgttgaa tttgcagatg agaaccatcg acaaatcgtt
     7981 tttggtgcga gaaatcggtt agatggatca acgacgatgc tattaggaca atcgattttt
     8041 atcaagcgac tagtcagctt tttaccgcgt aaattcccgg tacgtctgat gaaaaaaatc
     8101 ctccaggttt ttagccctca ccgacaaaag gatcgttatg aaacgttaga gatattaaaa
     8161 gaaccaattt atcaatgtat attgctcagt ccggagtcag aacagaaaaa gttagaacat
     8221 cgctttcccg agtgtacgtt tcagcgttca aatacgtata ctgtagatat catcccaaaa
     8281 ggtggttcaa aattactagg catccaagct ttcgcaaatg ctgtcgaaat tgaaatggaa
     8341 gaaattatgg cattcggcga tcattacaat gatatcgaga tgctgaaagg tgtaggaatt
     8401 ggagtggcca tggggaatgc tcagatcgaa gtaaaacatg ctgcagactt tgtgactcaa
     8461 tcaaatgaag aagatgggat atacgaagga ctgaaacact tcggtctgat ttattagtca
     8521 atgaaagaag gaaaaaatca gtatggaagc agagacacct tttcaaaaag tagaaacatt
     8581 ccacaaaact tttgatccaa gaagaccaga gatacccacg gcttttacag aaaatgaagc
     8641 tcatacacgt gctgcgttca aaatagaaga acttgttgaa tttgttgcag ctacttcacc
     8701 taataaagaa caactgcatg aagctgttat gctgctgcac gaagcattgg ataaagcaga
     8761 agaaaaaata cttggtaaaa cacagtgggg aagtgatccg ctggttgaac aagtagatgc
     8821 actgacagat atcctttact ttacttatgg ttctttttca ttactaggaa tagtgcctga
     8881 tcgaatattc gaaatcgtcc atcaggcaaa tatggggaaa ttatttccag atggaaaacc
     8941 tcattatgac cctgtaacaa ataaagtgtt gaaacctgaa aactggcaga tggaatatgc
     9001 tccagaacct aaaatcgcgg cagaaatcca acgtcagatt caagaagcga ttgctaagaa
     9061 gaaatccgct gatataggca tgtgcacaaa tgaaaaagag tgatcagagt ttcactattt
     9121 ttgttatctt tatacgatgg aaaaacaaaa gattttcgtt taagttagtg aatgcatgaa
     9181 aatagtatgc tataatctag aatagatgtc ttttgcacga gagacgtatt atttggattt
     9241 atgccaagca gaacgccatc tgttgcataa aagatgcata ctgaaaacgg aggaaccata
     9301 aatgggaaat aatgttatca tcggaatcgt cattgcaatc attatagtcg ccattgtcgt
     9361 ctttttggtt agttacttga tgaagaaaaa aaaccaagat cgattggatg ccttagaaaa
     9421 acgcaaggaa gaattatttg acttgccagt gattgaagaa gtcgatgatg ttaaaaaaat
     9481 gcatctggtt gggcaaagcc aaaatacctt tcgtgaatgg agtcaaaaat ggaatgacat
     9541 atctacttcc tcgttcgctg aactagaaag tcaaattttc gaagtggaaa acctcaatga
     9601 aagttttcgg ttcttaaaag gaaaaaaagc agttgttgaa gcagaagcta caatggacca
     9661 aatggagaaa caagtgacgg aaatccgtga aggtctaaag gaattgcggg aaacggaaga
     9721 acgcaactca ctagctgttc agcaggcact tgacgtctat gaagaactga aagaaaaagt
     9781 cagagaagac gagcatgaat acggaccagc tctttttgaa ttgcaaaaac agatcaaagt
     9841 gatcgaaaaa gaatttacgc agtttgtgac tttaaacact tctggagacc ctgttgaagc
     9901 ccgcgaggtt ttggataaag cagaaaaaca tacgtatgaa gtggaagctc tgatgaaaaa
     9961 aattccaccg ctgtatgagg agctccatac cactttccct gaacaacttg aagaaatcag
    10021 tgatacttac gagaaattga tggaagaaca atatgtattc ccagaagaag atcttgctga
    10081 agatatcgca aaagtaagtc gaagaattga aaattcatta gccaatcttg aaaaaacaga
    10141 agttgaaacg gtcgaatttg aaaaccgtga aacagctgat ttgattgatt cgttatatga
    10201 tatcttagaa cgggaaatgg aagctcagag atatgtaaaa actaaccaat caacgattgc
    10261 agagtatatc aaacatacaa caaagaataa ccgtcaatta ttgattgagc tggatcacac
    10321 atctcaaagc tatacattga accacaatga aattggccgt gtacgaggtt tccaaaccga
    10381 agtggaagaa atggaacgtc aaaatgaaca gatgattcca cagatccgtc aacacgaaat
    10441 tccttattca gaagtgcgca cgttctataa aacagtcttc aaagtcttag aagatatcga
    10501 aaagcaacaa gtagagatcg acgactcatt acatgaattg agaaaaggcg aaaaagaagc
    10561 gcaagaaaag atcgatacat tcgaattcaa attgcgcagt ttgaaacgtt ttgtagaaaa
    10621 acaacgtttg cctggcttgc cgaatgatta cctagaattc ttttttgttg ctactgaccg
    10681 tattgaagaa ctaagtgttg tcttgaataa aattcgagta aacatggaag aggtcaatcg
    10741 tttagttgct ctatgtgaag aagatctaga attattagat aagaagacac atgatttagt
    10801 agatgcagca gcattaacgg agcaaatgct ccaatatgca aatcgttatc gtcatacaca
    10861 cgaagaagtg agagaagcaa ttgataaaag ctactattta ttcaataaag aatatcacta
    10921 tcaagaagca ttagacgaaa tcggtacagc attagagcga gtagaacctg gtgctttcaa
    10981 acgcatcgaa gatttttatt ttaatcatcc agacttagta taaagcaaaa aagttagtaa
    11041 accagcaaga gcaagacgga ttattgtctt gttcttgtct ttttttgtat atttgaaaat
    11101 tgaaacaagt gaaaatttca cctgctcttg aaagcacctt ggacaaccgt tataatagaa
    11161 aagaatttca aaaaagaggg gtttcttatg atatattttg ataacagtgc aacaacccca
    11221 atctttccgc aaagcttaga tgcatatgta aaaaccagtc agcggattat tgggaatcca
    11281 tcaagcttgc atgatttagg caatcaagct aaccggttgt tgcagcaagc aagaaagcag
    11341 atcgctgatt tgatccatgt agaaccagaa gaaatctatt ttacttcagg cggaacagaa
    11401 ggagataact gggtattaaa aggaacgatg atcgaaaaaa gagaatatgg gaatcatatg
    11461 atcatttcag gagtcgaaca tccggccgtc agcgagacag cagaacaatt aaaagaatta
    11521 ggaatcgaag taagtatcgc cccagtggat aaacgcggat ttgtacgtgt cgacgaattg
    11581 aaagaattaa taagaaaaga gacagtatta gtctctgtta tggctgtgaa taatgaagta
    11641 ggatcgattc agcccatcca ggaaatcagt gatcttttgg atgattttcc taaaattcat
    11701 ttccatgtag atgctgttca ggcgattgga aaagtaccat tctcgcaatg gttgacagaa
    11761 agagttgatt ttgcaacatt ttcagctcat aaattccatg gcccacgggg aactggtttc
    11821 atttattgga aaaagggtcg tcgtttagca ccattactga caggtggagg gcaagaaaga
    11881 aatcagcgaa gtgggacaga aaatgttcca ggtattgtgg ctatggttaa agctttacgt
    11941 ttatcattag agataaagga acaaaaacct gagcagacac aacgcttaaa agtagctcta
    12001 atcaatgcgt tgaagacgta tgagaaagtg acgatttttt cagaaggaac tgactatgca
    12061 ccgcatattt tatgttttgc tctaaaagga attcgcggcg aagttctcgt ccatgcctta
    12121 gaagaaaaac aaatatttgt ttctactact agtgcctgct cctcacgtaa acatatggca
    12181 agcagtacat tgcacgcaat gcatgtacca aatgatctgg ctacatctgc tgttcgaatc
    12241 agcttagatg aaaacaattc gcttgcagaa gtcgagcaat ttatgattat tttcaagcag
    12301 ctttataaga aattttctgc aatcaattaa aagaggagtg ttcttgtgaa atacagtgaa
    12361 attatggtcc gttatgggga actttcgaca aaaggaaaga atcgaaaaag ctttatcatg
    12421 caactagcac aaaatgtcag acaagctttg aaagactttc cagaaatcaa aatccatgct
    12481 gatcgggacc ggatgcatct tttattgaat ggcgcagacg ggcagctagt tattccaaaa
    12541 ctagcaaaaa tatttgggat ccaaaatttc tctccaagta ttcgtgtaga aaaagatgtc
    12601 gaagttttga aacaagctgt tcaagacatc atgaaagaaa tttatactgg gaaagaaaca
    12661 tttaaaatta tcgctaaaag aagcgatcac caatttgaat tgacaagtaa tgaattgaat
    12721 caaacattag gtaatgctgt ttttgatatt ttcccgcata tccaagttca aatgcgtcaa
    12781 ccagatattc cattacgtgt agagattcgg cgtgatggcg cttatctatc gtatgaaacg
    12841 atcaagggag ctggaggatt gcccgtagga acaagcggaa aaggaatgct tatgctttct
    12901 ggggggattg attctcctgt agcagggtac tttgccatga agcggggagt ggaaattgaa
    12961 gctgttcatt ttgctagtcc gccgtataca agtgaacaag cactgcaaaa agcaaaagat
    13021 ctaacagcca aactagcacc ttatgtggga acgatccatt ttatcgaagt gccatttacc
    13081 gagattcaag aagaaatcaa aaagtcagtg ccacaaggat attggatgac aattactcgt
    13141 cgaatgatgt tgcgtttgac cgatgaaatt cgccgtattc gtcatggttt agtcattttg
    13201 aatggtgaat cattaggtca agtggcttca caaactttgc aaagtatggt ggctatcaat
    13261 gaagtaacga atacgccaat cattcggcct gtagcgacaa tggataaact tgaaatcatt
    13321 gaagtagcag aacagatcga tacatttaat ctttctatcc agccttttga agattgctgt
    13381 acgatttttg ctcctccaca gccaaaaaca cgccctcaac tggaaaaggt ccatcaatat
    13441 gaagagcgtt tagcaataga tgaaatgatc caacgagcac tagctggctt gaagatggaa
    13501 gagatacaag cagaatcgtc taatgaaaaa actgaagaat tttcagaatt gctataagag
    13561 gttatgaaaa tagtgttttg accagagtat tagagaaaca aaacgaaaaa atagctccat
    13621 gtattttacc gtttttgaac taatgtcgaa gattagctga ttgaatacca tttatcaaga
    13681 agttatggaa aagccggttc ttttttacta actgaaaaat aaaattttat ttagagatca
    13741 agctacagtt gataaatgat ataaaaaaga gaatttccca tgaaatagcg aggttgtgac
    13801 agaagtgggc agcttcaaga aataagaagg aatttacgaa aattgctttt caaatttttg
    13861 tgaaatttcg gcttattttt cgaagaagtt acttctggaa caccgtgtat cagaggttgc
    13921 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagtt cctcatattt
    13981 tacgtttggt tgagcttatt accgcagatg caagcttttg aacaccgttt tatttgtctc
    14041 acaccctttt ccttcctact tgtaaccttg ctcccgtgtt agaaacatgt tacactaaat
    14101 atgtgaaatt attaacaagg agcgtcgtta tgcgagaaaa aacagataca ctgccaaaag
    14161 caactgcgaa aagattacct ttatatttac gctacttgaa gatgctggat gactcaggta
    14221 taagtagaat caaatcaaat gagttcagcg aaatcaccca aattccttct gcaacgatcc
    14281 gcagagactt ctcgcaatta ggcgagctag gcagaagcgg atatggctat gatgtccctt
    14341 ttcttatcga tgtattcaat aatatcctta atactaaaga agaaaaacga atcgcattag
    14401 taggatatgg aaatcttggc aaagcattga aacacaacaa ttttagaaga aatgaaaatc
    14461 taaatatcgt gtgcgtcttt gataatgatc cagcactgat caatcgagta attgatggag
    14521 aaatgatcta tccgattgat cgtttcgcgg agatagccaa agcaaaaaat gtgacagtag
    14581 caatctctac ggtaccaagt aaatattcac aatctgctat tgatgaaatt gtcaaaggaa
    14641 atgtaaccgc tatacttaat tttgcgcctg acagagtaac tgtcccagct tatgtcaatg
    14701 ttcaatacat tgatttgaca accgagttgc agacgcttat ttactttgat gagaattact
    14761 cagaagtttt ttcttaggaa aatttgagta ggcttattga tcttgcgaga actcgtcgta
    14821 attctttcaa aaatttttta gtactaaatg aagtggtttt ttcacgacca cttgttgact
    14881 aaaaaaaaaa accattgtag aatgaagcat aacgctgaac aagaggagta actggcacat
    14941 tcattcttag agagagaact atctgctgaa aggttctcaa tgacaaccag tgaaggtagc
    15001 ttgggagttt ctgtcttgaa tggagtagag atagacgagt cgtgatcgtt aactcacttg
    15061 agaggcaata atgattgatt attgcaattt aggtggtacc gcgtaaatca tacgtcctag
    15121 aatacgaaag tattttagga cgttttttag tttaaaggag gaaaacagca tgacggaaga
    15181 aaataaccta tcaacaaaat ataatccgca agaagttgaa gctggacgtt atcagcattg
    15241 gttagaacaa gatttgttta aaccgagcgg agataaaaaa gcaaaacctt attcaatcgt
    15301 aatcccgccc ccaaatgtta ctggaaaact tcatttaggg catgcttggg atacgacctt
    15361 gcaagatatg ctgattcgtc aaaagagaat gcaaggatat gatactttat ggctgcctgg
    15421 tatggaccat gcaggaatcg cgacacaagc aaaagtagaa gcgaagctta gagagcaagg
    15481 gatttctcgt tatgatctag gtcgtgaaaa gttcatcgat caagtgtggg aatggaaaga
    15541 agagtatgcg agccacatcc gcgaacagtg ggctaaaatg ggcttatctt tagattacag
    15601 tagggaacgt tttacattag atgatggatt atctgaagca gtacgtaaag tttttgttac
    15661 cttatacgaa aaaggtttga tttatcgtgg tgaatatatc atcaactggg atcctcaagc
    15721 acgaacagct ctatctgata tcgaagttat tcataaagat atcgaaggcg ccttttatca
    15781 tatgagctat gaactagcag atggatcagg cgtagtagaa attgcgacaa cccgtccaga
    15841 aacgatgttg ggagatacgg cgattgctgt tcatccagaa gacgagcgtt atcaagcgct
    15901 catcggcaaa aaagtgattc tacctttagt caataaacaa atcccaatca ttgcagatga
    15961 atatgtagat atggaattcg ggacaggtgt agtaaaaatc actccagcac atgatccaaa
    16021 cgactttgag gtaggtaatc gtcatgatct tccacgcgta aatgttatgg atgatgatgg
    16081 tacgatgaat gaactagcag gaaaatatgc tggaatggaa cgttttgctg ctcgtaaagc
    16141 aatcgtgcaa gatctgaaag aaatcggtcg attgattaaa atcgatacga tgatccacag
    16201 tgtgggtcat tccgagcgga caggtgtcgt tgttgaacct cggctgtcta ctcaatggtt
    16261 tgtaaaaatg gcgccgttag cgaaaaaagc cattgataac caagaaacag atcaagcagt
    16321 ggaattcttc cctccaagat tcaatcaaac gtttttacgt tggatggaaa atgtccatga
    16381 ttgggtaatc tcacgacaat tatggtgggg acatcaaatt cctgcatggt atcacaaaga
    16441 aacaggtgaa atgtatgtag ggatggaagc accagcggat agtgaaaact gggtacaaga
    16501 tcctgatgtt ttagacactt ggtttagttc agctttgtgg cctttctcaa caatgggctg
    16561 gccagatacg gaaagcgaag attataagcg atacttccct actagcactt tagtaaccgg
    16621 ttatgacatc attttcttct gggtaagcag aatgattttc caaagcttgg aatttactgg
    16681 cgaacgtcca tttgagaatg tcttgattca tggattgatt cgtgacgaac aagggcggaa
    16741 gatgagtaaa tcattaggta atggaatcga tccgatggaa gtaatcgaaa agtatggagc
    16801 agatgctctc cgctggttct tatcgaatgg ttctgcacca ggacaagatg tccgcttcag
    16861 ctatgaaaaa atggatgctt cttggaactt tatcaacaaa atctggaatg cttcacgttt
    16921 cgttatcatg aatatcgaag gaatgaccgt agaagagatc gatttatctg gagaaaaatc
    16981 agtggctgac cggtggatcc ttactcgttt gaatgaaacg atcgaacgag taactgagct
    17041 atttgatcgt tttgaatttg gtgaagcagg tcgacaactg tataacttta tctgggatga
    17101 tttttgtgac tggtacatcg aaatgagtaa agaagtactt tatggagatg atgctgtttc
    17161 aaaacaaacc acccgtagca tcttagtcca tacacttgat cagatcctac gtttattgca
    17221 tccaatcatg ccattcgtta cagaagaaat atgggaacat attcctcatc agggaaattc
    17281 tctagtagtg gcagaatatc ctgttgtacg tccagagttt gatgatgaaa cagcttctaa
    17341 agggatggaa gtattgaaag aattgattcg agccgttcga aatattcgtt cagaagtgaa
    17401 tacaccattg tctaaaccaa ttacgttgct aattaaaaca aacgatgcta aaatcgatca
    17461 atttttagtt gaaaatacaa gctatatcga acgcttctgt aatcccgaag agttgacgat
    17521 atcaagtgag atcactgcgc cagatctagc gatgtcagct gttctgacag gtgcagaaat
    17581 cttcttgccg ttagcaggat tgatcaatat tgaagaagaa atcaaacgat tagaaaaaga
    17641 actggaaaag tggacaagcg aagtaaaacg tgtccaagga aaactttcta atgaacgttt
    17701 tgtttctaac gcgccggaag aagtagtaga ggcagagcgt gcaaaagaaa aagattattt
    17761 agagaagcaa acggctgtca aagaacgaat cgaaagtttg cgtactattc aataagaata
    17821 gaaaaagaga gtgtgaaatc agctagctat tactaaaagc tagctgattg aacatcgtta
    17881 caggaaagag tttgagcctc actcttagct tcgattcata aggagatgtg acataaattt
    17941 tgtcgcatct cttttttagt ctactcttat tatgtaggag aaggagggag gtggatcatg
    18001 tatcaagagt caataaagta gttgataaaa tcgttcctct ctctgtttct tttctctttg
    18061 tcatactttt atttttctta tgtgttctat ttgttataat aaaagagaaa tgggggaatt
    18121 gttgatgacg attgaagaag caatagaatg gatccatagt cgattaccat ttggttcacg
    18181 tcctggcctt gaccgagtcg aagctttatt agaagtggta gggcatccag agagaaaagt
    18241 aaaaacgatc catatcgctg gaacaaacgg aaaaggttct actgtagctt atttgagaag
    18301 cctattagaa gaggctgggc tgacagtagg tacatttact tcaccttata tcgaaacgtt
    18361 caatgaacgg atcgcaatca atggcaaaag cattccagac aatgatttga tccagcttgt
    18421 aaaaaaatat cagccactga tcaaacaact tgatcaattt gaagcagtag ctggtattac
    18481 tgaattcgag acattaacag caatggcatt tgattatttt ttgatgaaga aagtggacgt
    18541 agcgattatc gaagttggct taggcggctt attggattct accaatgtag ctgtaccaat
    18601 gctgacggga ataacaacga ttggacttga tcataccgaa atacttggag atacaattga
    18661 agaaatcgct gcacaaaaag ctggaatcat caaacaaggc gttccagtag taacaggaaa
    18721 tattgcccca gaagctttta ctgtcatcca acaaacagct aaagcaaaaa atgcaccgct
    18781 ttatgtatac ggggaaaatt ataaaataaa ctatctgcat cctgatgaga tgtggggaga
    18841 agtatttgaa ttttttaatg aaataggaaa gatccctcaa ttaaccactc cgcttttagg
    18901 gcaacatcaa gctgaaaatg caggagtagc catcgaattg tattttgttt actgtcaatt
    18961 ggaaaagctg cctttccgag aaaaagatgt tttgaaggga ttgaagaaat ctcgatggcc
    19021 aggaagaatg gagcgtttga gtaacgagcc attagttgtt ttagatggtg cccataatac
    19081 gcatgcaatg aaccggcttg ttgagaattt gaaaaaagaa ttcaaaggat atcaaatcaa
    19141 cattttgttt tccgccttac gaactaaaaa tgttagagaa atgctagaac gattgcagca
    19201 agtaccaaat gtccatattt atttgacgac ctttgaacat ccaaaagcca tcgaattaag
    19261 tgaagtatca gatttagcaa gtgagagagt atcaatcgtt tcattgtggc aattcggatt
    19321 agcagatata ttggaaaaga tgacaaatga agacgtatta gttgtgaccg gttcacttta
    19381 tttcatttca gaagttcgcc atttattaat acaattagga ggagatcatg aagtataatg
    19441 cagtgatttt tgacatggat ggtttgctgt tcgacacaga gttagtgtat tacgaagcca
    19501 cacaagtagt agcagacaag atgggttttc cttatgataa agacctgtat ttaaaattct
    19561 taggtgtttc agatgaagaa gtatgggcga attatcatat gattttctcg gaatttggca
    19621 aaacaagtgt acaaagattc atagatgatt cataccagga aacgcttgaa cgtttttcgc
    19681 aaggagcggt acaaatgaag cccggtgtgt tggaactcct ctctttttta gaagaacatc
    19741 agattcccaa agttgtcgct tccagtaacc aacgagcagt cattgaactt ttattgaaga
    19801 agaacaatct gtttgaacga tttgagacga ttgtttctgc agaaaatgtt caacgagcaa
    19861 aaccagaccc agaaattttc ttgttagcta atcagaagct aggtacagcg aagaaagaaa
    19921 cattgatttt agaagattca caaaatggta ttttagcagc ttctgcggct gagatcccgg
    19981 tagtcatggt accagatctg cttccaccat cccaagaatt gatcaaaaaa acagctgggg
    20041 ttgtttcttc tttacatgaa atccctgcat tgttaaaata aaaatccatc tcttttcgta
    20101 tcttatttta gataagatag aaaggagatg tttttttggg aaaacgattg atcaaagaag
    20161 tacctactag ctctttacca agggaacgta tggaaattta tggcgcggaa gctttatcgg
    20221 atcaggagct tttggcaatc ttactgcgta ccggtcaaca cccttatagt gtgatgtcga
    20281 ttgctggaaa tctgttaaaa acgtttggag gactggcctc tttacgacag gctactttgc
    20341 atgagttaga agagattcga gggataggac gcgtgaaagc aatcgaaatc aaagccttga
    20401 tcgaattagg tcgacgaatt cagacggatc atgaaagagc ggctccaccg gttcgtacca
    20461 gctacgaatt ggcccagcaa ttgattctgg aaatgaaaga tcacaaacaa gaacatttgg
    20521 tttgtattta tttggacacg aagaatcaag tgatcttaaa aaaaacagtg ttcatcggtt
    20581 cgctgaatca gtcagtcgct catcctagag aaattttcca ttatgctgta cgttattgtg
    20641 cagcaaggat cgttttagcg cataatcatc cttctggtaa tgttattcca tcgcagcagg
    20701 atatgaattt taccaaaagg atacaaaagt gtggagaaat gatggggatc actgtactgg
    20761 accacttgat catcggacgc aaacgatatt ttagtttgag agaagaagga atgatggaag
    20821 agaagtaagt tgctttcttg caaaaaaaat gaagcaagtg tacaattata ttgtaatttt
    20881 gtttgggaat agaagttgaa acatctgttg cacctctatc gtacacgagc aatgttacaa
    20941 tttaaattag tgcttttggc acgaggagga tattattatg gaaaacggaa cagtaaaatg
    21001 gttcaacgct gaaaaaggat ttggatttat ctcacgtgaa gatggaagcg acgtattcgt
    21061 tcacttctca gctatccaag gtgacggatt caaaacatta gaagaaggtc aagcagtgac
    21121 tttcgacgtt gaagaatcag accgcggccc acaagctgca aacgttgtaa aagcttaatt
    21181 ttatctgtaa atcaaattga tggtagacat caatttttac gagagaacaa agcgagtaac
    21241 aaaaatacct gccacaagag acaatttctc ttgtggcagg tatttttttg tatgaaaaag
    21301 taaataaatt taagaggcta tgaaagagcc accttgtatc aaggaataag aacaaacaaa
    21361 aatggcttct catgtttttc atttgttttc tcttatattc aggacaaggt gctgatttca
    21421 taacctctta tttattcttc atctggtgtc attaccattg gcaaaatcat tggatgtctt
    21481 tctgtacgtt cgaataagaa aggctgaagc gcgccagtca tcgcttcttt caatttatat
    21541 tctgaacagt caggtccatt caaacattct cttaaagcgt ggaataagat tcgctgagct
    21601 tcattgatca tttctcctga ttctcgcatg tagacaaatc cacgagagag aatatctgga
    21661 ccagccaaga tttctttttt cttgatatcc actgtcgcga cagctaatac aagaccttct
    21721 tctgaaagca ggtgacggtc acgtaaaacg acattaccaa tatcaccgat cccgctacca
    21781 tcgatataca catctccagc cacaaaatgc ccagcaggac gcgcagaatc gctagttaac
    21841 gctaaaacat cgccattttc catgatgaag cagttttctg caggaacacc tacatcttgt
    21901 gctagagaag catgtacttt caacatgcgg aattctccgt ggacaggaat aaaatatttt
    21961 ggcttcatca aacgaagcat taatttttgt tcttcttgtc caccgtgacc ggaagtatgg
    22021 atgttattga tttttccgtg aatcacttct gcaccagctt cagacagcaa attgatcaaa
    22081 tgattgacac ttgttgtatt accaggaata ggtgaacttg aaaagatcac tgtatcgtct
    22141 ggctggattt ggatttgacg gtgagtacca ttcgcgatgc ggctcaacgc ggccatcgct
    22201 tctccttgag aacctgtaca taggatcatc gtttcattgg caggcaagcg attgatttcg
    22261 tgtgcatcta caaatgtgcc gtctggaact ttgatatatc ctaaacgttg accgttgacg
    22321 atggcatttt ccatgcttcg tccgaaaaca gcgattttac gaccagttgc cacagcggca
    22381 tctgctgctt gctgcaaacg gaagatgtta gaagcaaagc tggcaaaaat gatacgtcct
    22441 tcgatttttg aaaagatctt caaaatagaa tgcccaatcg ttttttctga tttagtaaat
    22501 gttggaatct cagcatttgt actatcagat aaaaggcaca agactccttc ttccccgata
    22561 cgagccattt tatgcaagtt tgctggttcg ccaacaggag tgaaatcgaa tttgaagtct
    22621 ccagtcgcta cgatatttcc agaaggtgtt ttcaccacga tccctaatgc atctgggata
    22681 ctatgggtcg ttctgaaaaa gctgacagaa gtctttctaa aacggatgat cgtatcttca
    22741 ttgatctcat ggagctctgc atctcgaagc aagccatgct catctaattt gtttgtgatc
    22801 aacgctaatg cgagaggacc agcatagata ggaatatttg cttgtttcag caagtagggt
    22861 attccgccga tgtggtcttc gtgcccgtga gtaatcacca aggcttttac tttgtgtaag
    22921 ttttgtatga tgtagctgta gtcgggaatg acatagtcaa ttccaagtaa atcgtcttcc
    22981 gggaatttga tcccggcatc aatcaaaatg atttcatctt ggaattgtac cccatacgta
    23041 tttttcccga tttcacctaa tccaccaata gcaaagacgc ctgtctcgtt atttttgatg
    23101 gaaagtttca tattaaaact ccactaatga gaaatcagca ttttcttttt cgtactctag
    23161 atgacttcct tctagaagtt gaacgaattc aatattgtat ggggtatttt cttccacacg
    23221 ttggcgagcg tctacatcgc tttttgcctc aatgtaaaga gattttgttt cttcccgttt
    23281 agggttgcgt acttttgttt cttgataata aactttatag atcattgttt tgtctccttt
    23341 atctgcgtaa agcagtgatt tagctagttg atttttttag acaacacaaa acgaggggac
    23401 aagccacctg gtttttcata tgctttgact agaatactgg attcgagtca aagagacaag
    23461 cctcgttttt gcttatctgt tcggatattt tttcaaccgt accttctgta taaaaaatat
    23521 acaacaatta attgttattc tagcataaaa cagcaaataa gtatagaaat caactagatt
    23581 gaaagaaaaa atcaatgttt atcatcccgc tataatcata atgacttttt tatgagagaa
    23641 gtgttctatt aataggctcg ttgtgctatc atttttagta atgaaaatgt aacaaaagat
    23701 taaaaggaga tgagaaagtg aaactaatgt ggcattatac catgcgttat aagaaattct
    23761 tgtttttcaa tttcatatgc gtatttggtt ttattttgat tgaattagga cttcctacga
    23821 ttttagcacg tatgatcgat gtaggaatcc gcaatgatga ttttgattat gtgaagcaac
    23881 aagggatatt tatgatcgtt attactgtaa tcggtattat tttgaatatc ttgttaggtt
    23941 attttggttc gaggattacg actaatatcg tagcagatat tcgagatgat ttgttcgaaa
    24001 agatccaaag ttattcgcat caggaatacg aaaatctagg cgtatcttca ttgatcactc
    24061 gtacaacaaa cgatgcttat cagatcatgt tgttcctgca aaatatttta cgtatcggtt
    24121 ttatggcacc aatgatgttc attgtcagtt tgtacatggt catgcgtaca agtgtgacac
    24181 tcagtttgta tgtagtaggt gcattacctt tactattatt ggcagtcgta gcgattgcta
    24241 aggtgtctga accgttatct aaaaagcaac aaaaaaactt agataaaatc aacagtatct
    24301 tgcgggaaaa tctttcagga ttgcgtgtga ttcgtgcatt cgtcaatgaa aagtttgaag
    24361 aaaaacgttt tgctgtagtc aatgagaatt atgcttctag ttcaaaaagc ttattccgtt
    24421 tgatggctgt tgcacaaccg ggtttttatt tcttatttaa tatcgtaatg gtattgatca
    24481 tctggagcgg ggcagtgcaa atcgatgcag gcgagcttcg tgtaggagat ttgattgcgt
    24541 ttatcgagta tatattccat gccttgttct cattcatgtt atttgctagt gtgttcatga
    24601 tgtatccaag agcagctgtt tcagctggac gtatccaaga agccctagat gccaaacctt
    24661 cgattgtaga agatccaaat ggtatatctg atacaaaaac taaagggtat atcgaatttc
    24721 aaaatgtaac atttgcttat ccaggccatt cgcaagagcc agtgatacga aatgtcagtt
    24781 ttacagcctc tccaggagag accgttgctt ttattggaag taccggtagc ggaaaatcta
    24841 cgttgatcca attgatccct cgcttttatg atgtgagtga aggaaagatc ttgatcgatg
    24901 gagtagacgt gagagattat cggctaagca agttgcgaga taagattggg tttattccgc
    24961 aaaaagcgct gctatttact ggaacgattg cagataattt gcgatacggg aaagaagatg
    25021 ctacgcaaga agaaatggaa cgtgcagctg agattgctca agcttcagaa ttcatttctc
    25081 gaaaaccaga tggatttaat gaacatttat cagaaggtgg ttccaatttt tcaggtggac
    25141 aaaaacaacg attggcaata gccagagcca tcatacgccg tccggaaatc tatatttttg
    25201 atgacagctt ttctgcatta gattatcaaa cggatgcgaa gttacgtgct cgtctgaaaa
    25261 aagaaacgac agaatctact gtattgatcg tagcacaacg tgtgggaacg atcatgcatg
    25321 cagataagat catcgtatta aatgaaggag aagtcgtcgg tatggggacg catcgggagt
    25381 tgttggaaaa atgcccgatt tattatgata ttgccgcttc tcaattatca aaggaggaat
    25441 tagcatgaaa aaaacctttt cttccttaaa acgtttagct cgatatatca gaccgtatcg
    25501 tgagactttt cttttagtga tcctatttac agttctgaca gtggctttca acgtggcttt
    25561 gccatatgtt acaggacttc ctactacaga aatcagccgt aatattgcca atggcgaatc
    25621 aatcaatttt tcttatatat tcaaatgtct catttggatc acagttgttg gaatagggta
    25681 ttgtatttcg caattacttt ctggtgtttt gatgacaaat gtcgttcaaa gtgccatgca
    25741 tgatttgaga agagacatag aagaaaaaat caatcgtctt ccggtttcat atttcgataa
    25801 aaaccagcaa ggaaatattt tgtctcgtgt gacgaatgat gtagatgcag tcagcggtgc
    25861 tttacaacaa gcttttattg gtatcgtaaa tgcgatattg ggaattacgt tggctgcagc
    25921 aatgatgttt tatatccagc cgatgatggc gctgatctct atgatcatga ttccaacatc
    25981 gatctggatc tcaaaacgag tgatcaatgc ttcgcagaaa tattttcaaa gcatgcagaa
    26041 ttctcttggt gagctaaacg gctacgtcca agaaaatatg acaggtttta gtgtattgaa
    26101 agtatatgga cgcgaaaaag aaacattgga aggattcaaa aaagttaatc acagcttgaa
    26161 atactttggg tttcgtgcag cattcatttc tggcttgatg atgcctctag ttcaattaac
    26221 tgcctatgct acttatattg gtatggctgt tctaggaagc ttttatgtta ttactggggc
    26281 gatcgttgtc ggtcaactac aagcattcat ccaatatatt tggcaaatca gtcagccaat
    26341 ggggaacgtg acacaattgt cttcagtttt gcaaagtgca tcagcggcaa cgaaacgtgt
    26401 attcgagatt ttagatgagc cagaagaaaa agaaaacaaa gtagatgctt cactgccaga
    26461 aacgatttta ggagatgtga cattcgatca tgtcgatttt gcatatgatc cgaagaaacc
    26521 attaatccaa gatttgaatt ttgaagtgaa agctggtcaa accgtagctg tggtcggtcc
    26581 gaccggtgcc ggcaagacga cattgatcaa tctattgatg cgtttttatg acgtagacaa
    26641 aggagcaata aggattgatg gaatcgacac caaatcaatg agtcgcagtg atgtgcgttc
    26701 gctatttggt atggtcttgc aagatgcatg gctttatcaa ggaacgattg cagataatat
    26761 ccgcttcgga aagcttgatg cgacagatta tgaagtagtt gatgctgcga aaacagcaaa
    26821 cgtagatcat tttatccgaa cgatgccaga tggatatgat atggccatca attctgaggg
    26881 agacaatgtg tctttaggac aaaaacagtt gctgacgatt gcccgagcag tggtctccga
    26941 tcctaaaatc ttgattttag atgaagcaac aagttcagta gacacccgtt tagaagcgtt
    27001 gattcaaaaa gcaatggatc gcgtgatgga gggacggaca agtttcgtca tcgctcaccg
    27061 tttatcgaca atccgtgatg cagatctgat tctagtgatg gatcaaggtc agatcattga
    27121 aaaaggaacg catgagagtt tattggcaca aggtggattt tatgaaaaac tgtataacag
    27181 ccaatttgct gaggaagcag aataagtcat ataagaataa aacagtttaa aacttatttt
    27241 ttgttctcta ttcttgataa tggtaaagta aagttatcaa gaaaagtgag gacacggaga
    27301 tggaacagtt tttaaatgaa aaaattactg aagccaaaag agaagttgat cgtttaacgc
    27361 acgtctgtca gacgaagcct tttgattcag ctgatttttt tgaaaatgag tttcaaatcg
    27421 aacgcttggc agcacaaata gaagtgtacg aattaatttt aaaaaaagta atagaagaaa
    27481 atatagatgt acaataaaaa caggtaaaac gtcagttacc agatactgta aatagacatc
    27541 tggcctgagc aggttttacc tgtttttttt cttatgaaat aaatatatgc tatgatacct
    27601 ttattcaata ggattagttt ctacaaaaaa tgaaaggaga aaaataaata tggaacggtt
    27661 tatagcatca aatgccacag tgattggtga tgtgacattg tcagaagatg tgacgatctg
    27721 gtatcaagct gttttacgcg gggacagtaa ttggataaaa ataggacaaa gaacgaatat
    27781 ccaagatggt acaatcatcc atgtcgatca tgatgcacct gtagatattg cggagaatgt
    27841 gacggtagga catcagtgca tgctacatgg ctgtacaatc gaaaaagggg cgctgatcgg
    27901 gatggggacc acgatattga atcatgcggt tattggtgag aatagtttga ttggtgctgg
    27961 atcattagta acagaaggaa aagttattcc tcctaatgtc ttggcttttg gtcgcccagc
    28021 taaagtgatc cgtcctttga caaaagaaga aatacaaaaa aacaaagaaa acatccagca
    28081 ttatgtcgag ataggtcgga tgcatgcgca aggaaaattc aaggagcaaa gataggcagt
    28141 agcatccata aaataaaaaa ggatggtcag tttgagttga ccatcctttt ttatttggtt
    28201 tagataagag agcttaaaaa agcttccttt gaaacagatt aatttaatga agaactgttt
    28261 tccatgactt catcgatcaa tccatatgct tttgcttgtt cagctgtcat atagttgtca
    28321 cgatctgtat ctttttcaat cacttcaagc ggttgtccag tgcgttcagc taaaattttg
    28381 tttaagcgtt cgcgtgtttg caaaatatgg cgtgccgcaa tttcgatttc agttgcttgc
    28441 ccttgagcgc cgccaagagg ttgatggatc atgatctcag catttggtaa agcaaatcgt
    28501 ttaccttttg taccagctgt cagcaagaag cttcccattg aagcagccat acccataaca
    28561 attgtttgga catctgcttt gacaaagttc attgtgtcgt aaatagccat acctgctgta
    28621 actgaaccac caggagaatt gatataaaga tagatatctt tttcagaatc ttgagcgtct
    28681 aagaaaagca attgggcgat gatcgaatta gcaagatcat ctgttacttg gccgcttaac
    28741 atgatgatac ggtctttcaa taaacgtgag tagatatcgt aagctctttc acctcgtgaa
    28801 gattgttcaa tgactgtagg aattaaattc ataatagagt tcctccttga tttcgtttag
    28861 aaatagtgta ccataattta gtttctaata cctaaaatgt agtatacatt tttggtcaaa
    28921 aaaggtcaaa taaaaaactt aggcaaatta gtcgcataaa cccgctttat ggtatgataa
    28981 gcagagaaac aaaacaagga ggaacaacag attgatagtt ggtattactg gccttatcgg
    29041 agtgctgaca ggtgctgtag ttgtctatat cggcatgata ctgcaaatgc gtcacttgga
    29101 aaataaagaa cagcgtagac gtgaattgga attgaaagtc aaagaaatcg agacgctgaa
    29161 tcaattaaat aaaaagatca acgagatctt gcaaaaacgg acaacgctga tggaagaata
    29221 tgtcagcttt gatgcatttg atgattgtta tatcacgatt gacgattttg cgtatctcca
    29281 atcattttca gcgcaaaata gtttttatct gccaaattat attttagacg agctatttaa
    29341 gaatatctcc catcgaaaag tgattttatc tccagatgaa acaatgaaga ttggtggata
    29401 tgcttataaa ggcggacgcg tgattttaga gaattttacg gatagtctga ctgaaatgat
    29461 caatgaaaaa aaagctcagt tgaagactat gacgcgccag ccgattggtt tcttctcgaa
    29521 agatgatgtt tgaagctgat attttgaagc attgccgttg cacatgagag cgtggtaatg
    29581 ctttcttttt ttcttaatga tacaatagaa ctgaacggag tgaagaaaga tgttacaaat
    29641 ctatgcccat cgcggaagca gcggcaccca cccagaaaat acgcttcctg catttgcaga
    29701 agctgtacga gtaggtgcag atggtatcga actagatgtc catctaagca aagatggtta
    29761 tttgatcgtt atgcacgacg aagaagtgga ccggacgact aacggtaaag ggctgattcg
    29821 agaaaaaaca ttggaagaac tcaaaaaatt gaatgcaggg ggcaaattca gcaaagaatt
    29881 tccagcagct aaagttcctg aattgagaga agtgttagga ctgctcctcc aaaaaaatta
    29941 ccgagggatg ctaatgattg aaattaaaac tgatcagtat gaatatcccg gtatcgaaga
    30001 aaaattagcc gaaacattaa aaagtagaga ttggcctttt caacatgcat attgcagctt
    30061 tcatttggat tctttggaaa aaatcgcatt actggaaccg gagatacagc tggacttatt
    30121 gatgagtact tctgataaaa agatccaact agcagcagaa accccttata tagaaggagt
    30181 acatccaaaa aatacttggt tgttcgaaca tccagtccag gcagctgatt ttccaaaagc
    30241 aattcgtgca tggacgatta acgatgaaga agaaatggcc aaatgtcaag aactcaaaat
    30301 agatggaata ataactgatt ttccggagaa agctcttcgg tggaaacaat caacgaaaag
    30361 taggtaaaat atggaaaaag tattagtgat cgtcggtccg acagcagtcg gtaaaacagc
    30421 gctaagtgtg gaactcgcac aactatttgg aggagagatc atcagtggtg attcattgca
    30481 aatctataaa aatctggata tcggtacagc aaaaatcaaa gaagaagaga tgaataatgt
    30541 tccgcatcat ttgattgatg tgatcgaacc tactcaacgt tactcagccg ctgattttca
    30601 gcattcaggt cgacaattga ttaccgagat tgcgaaccga gggcacctac ctatcatagc
    30661 tggtggtacg ggtctctata tccaatccct tctatatgat tatcagttag gagcgacaga
    30721 agaagcgaat cctgagatta gaaaaaagta tgaaacgtta gctgaaacaa ttggttccca
    30781 agcattatgg aatcagttga aagaaaaaga cccggcagct gctgagaaaa tccactggaa
    30841 caatcaacgc aaagtgataa gagctctgga agttttagag acgacaggac atagtatcac
    30901 ggcacctaaa gaagagccaa agcaattgta tgattacctc atgattggat tagatacgaa
    30961 gcgtagtatt ctttatgaac gaatcaatca aagagtcgat ttgatgctag cagaaggttt
    31021 agtagcagaa gcgcgtaagg tgtatgagct tggagaagtc caggccagtc aaggtattgg
    31081 atataaagaa tttttccctt attttgaagg gaaagaaaca ttggaagaag caacagaaca
    31141 agtcaaacta cattcgagaa gatacgcgaa acgtcagttg acgtggtttc gtaaccgttt
    31201 ggatgcacag tggtttgatc ttataagtga gccaaatcaa aaaagtcaga ttgagcaaac
    31261 aatcaaaaaa tggctggagg cggaataaaa tggaagaaaa agtgatcatc gtaggggtag
    31321 aaaccgaagc aaaccagcgt tacttttcag agtcaatgga agagctagtt cagctgacga
    31381 ataccgcatc aggagaagtc gtattcacaa ttacacaaaa gagaccacaa gtgaatcggc
    31441 aaacgattat cggtaaaggg aaattacaag aattagttca acaagcggat gcgcatgaag
    31501 cggatttgat catctttaat catgagctaa ctccgagaca gagccaactg attaccgatg
    31561 ctgttggtct tccggtaatt gatcgcgtgc agcttatctt agatattttt gcgatgcgtg
    31621 ctcgttcgaa agaagggaag ctgcaggttg aacttgctca gttagaatac ctgctgcctc
    31681 gtttagtagg gcaagggaaa acattatctc gtcttggcgg tgggatcgga acaagagggc
    31741 caggtgaaac aaagttagaa acagaccgcc gacatatacg gaataaaatt tttgctgtta
    31801 agaaagaatt gaaagaagta gaagctcatc gagagcgcaa tcgccaaaaa agaaaaaata
    31861 gcgagatttt tcagattgga cttattggct acacgaatgc cgggaagtca actatcttga
    31921 atctattgac acaagcggat acttattcga aagatcaatt gtttgcaacg ttagatccat
    31981 tgactaagag atggcgtttt gctgaaggat ttgagattgc tgtaacggat accgtcgggt
    32041 tcatccaaga cctgcctacg caactgatcg atgctttcca ttctacatta gaagaaagtc
    32101 aaaatatgga tcttttgcta catgtagtcg atgctagttc tccagatcgt attttacagg
    32161 agcagactgt cttaaaattg atggatgaac tgaatatgaa agaaatgccg atactgactg
    32221 tttacaataa ggcagaccag atcgacccag cgatgttcac gcctacgcta ttcccaaatg
    32281 tattgatttc tactcagacg aaagaaggta agatggcgtt gatcgaagca atcaaacgtc
    32341 agctgatgga actaatgacc ccttatacac tttctgtgcc aagcaacgaa ggacagaaat
    32401 taagcgagtt gagaagacaa acaatggttt tggacgaagc gtacatggaa gaaacaaacg
    32461 aatatgaagt taaagggttt gcaaaaacca attcaaaatg gttaagaaaa aaccaataaa
    32521 attttatttt tttaa
//
LOCUS       DAXLPC010000026        29879 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.026, whole genome shotgun sequence.
ACCESSION   DAXLPC010000026 DAXLPC010000000
VERSION     DAXLPC010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.026"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(87..497)
                     /locus_tag="ACF3UE_001139"
     CDS             complement(87..497)
                     /locus_tag="ACF3UE_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFD3634586.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(678..1112)
                     /locus_tag="ACF3UE_001140"
     CDS             complement(678..1112)
                     /locus_tag="ACF3UE_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3634587.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTDNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(1212..2060)
                     /locus_tag="ACF3UE_001141"
     CDS             complement(1212..2060)
                     /locus_tag="ACF3UE_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3634588.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            2449..4215
                     /locus_tag="ACF3UE_001142"
     CDS             2449..4215
                     /locus_tag="ACF3UE_001142"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFD3634589.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            4317..5576
                     /locus_tag="ACF3UE_001143"
     CDS             4317..5576
                     /locus_tag="ACF3UE_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3634590.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            5723..7024
                     /locus_tag="ACF3UE_001144"
     CDS             5723..7024
                     /locus_tag="ACF3UE_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3634591.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            7027..7878
                     /locus_tag="ACF3UE_001145"
     CDS             7027..7878
                     /locus_tag="ACF3UE_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFD3634592.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            7891..8706
                     /locus_tag="ACF3UE_001146"
     CDS             7891..8706
                     /locus_tag="ACF3UE_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFD3634593.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            8857..10023
                     /locus_tag="ACF3UE_001147"
     CDS             8857..10023
                     /locus_tag="ACF3UE_001147"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3634594.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            10253..10900
                     /locus_tag="ACF3UE_001148"
     CDS             10253..10900
                     /locus_tag="ACF3UE_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFD3634595.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            10984..11928
                     /locus_tag="ACF3UE_001149"
     CDS             10984..11928
                     /locus_tag="ACF3UE_001149"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFD3634596.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            12063..13514
                     /locus_tag="ACF3UE_001150"
     CDS             12063..13514
                     /locus_tag="ACF3UE_001150"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFD3634597.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLIRSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            13535..14371
                     /locus_tag="ACF3UE_001151"
     CDS             13535..14371
                     /locus_tag="ACF3UE_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFD3634598.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            14371..15030
                     /locus_tag="ACF3UE_001152"
     CDS             14371..15030
                     /locus_tag="ACF3UE_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD3634599.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            15156..15845
                     /locus_tag="ACF3UE_001153"
     CDS             15156..15845
                     /locus_tag="ACF3UE_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634600.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            15851..16807
                     /locus_tag="ACF3UE_001154"
     CDS             15851..16807
                     /locus_tag="ACF3UE_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFD3634601.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            16851..17363
                     /locus_tag="ACF3UE_001155"
     CDS             16851..17363
                     /locus_tag="ACF3UE_001155"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3634602.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(17619..18167)
                     /locus_tag="ACF3UE_001156"
     CDS             complement(17619..18167)
                     /locus_tag="ACF3UE_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFD3634603.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(18256..19437)
                     /locus_tag="ACF3UE_001157"
     CDS             complement(18256..19437)
                     /locus_tag="ACF3UE_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFD3634604.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(19673..21181)
                     /locus_tag="ACF3UE_001158"
     CDS             complement(19673..21181)
                     /locus_tag="ACF3UE_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFD3634605.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            21340..21531
                     /locus_tag="ACF3UE_001159"
     CDS             21340..21531
                     /locus_tag="ACF3UE_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634606.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            21734..22651
                     /locus_tag="ACF3UE_001160"
     CDS             21734..22651
                     /locus_tag="ACF3UE_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFD3634607.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            22644..23717
                     /locus_tag="ACF3UE_001161"
     CDS             22644..23717
                     /locus_tag="ACF3UE_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634608.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            23865..24383
                     /locus_tag="ACF3UE_001162"
     CDS             23865..24383
                     /locus_tag="ACF3UE_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634609.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            24364..24756
                     /locus_tag="ACF3UE_001163"
     CDS             24364..24756
                     /locus_tag="ACF3UE_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFD3634610.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            24832..25767
                     /locus_tag="ACF3UE_001164"
     CDS             24832..25767
                     /locus_tag="ACF3UE_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFD3634611.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            25900..26679
                     /locus_tag="ACF3UE_001165"
     CDS             25900..26679
                     /locus_tag="ACF3UE_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFD3634612.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVFFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            26672..26989
                     /locus_tag="ACF3UE_001166"
     CDS             26672..26989
                     /locus_tag="ACF3UE_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFD3634613.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            27233..28843
                     /locus_tag="ACF3UE_001167"
     CDS             27233..28843
                     /locus_tag="ACF3UE_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFD3634614.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            29000..29848
                     /locus_tag="ACF3UE_001168"
     CDS             29000..29848
                     /locus_tag="ACF3UE_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD3634615.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT         9707 a         5325 c         5886 g         8961 t
ORIGIN      
        1 tacttgatta actaaatata gatcttccat ttttccacct ccgctgtttt actatagtgt
       61 atcatagcgg atttacacaa aaaagtctat tcactaactg ctttcagagt aacttctata
      121 tttccagctg tagcttttga atacggacac actttatgcg ctgcctctaa taattcttgc
      181 gtttcttcca gagaaagacc ttcgatagat ccttcaatct ctacacctaa gacaaagctc
      241 gtttcacttt ctgaataaag ggaaacttgt gcactgacag tagaagcccc agagatattt
      301 ttttgctgtt tgatcaattc taatgcactg ttaaaacatg cactgaaacc agctgcaaac
      361 aattgttcag ggttggttgc attttcgacg cgtttaccag gagctgcaat attcaattcg
      421 aatgtacgat cgggattatg aacttctcca gagcgtccgc ctgtgttgat cattttcgta
      481 gaatacattt ttttcataaa attaccacct ttaattatat tttatacaat tgaattttac
      541 acaatataat tgtggaaagc aaagaaatgg attggcataa gataaataag agaaagcaca
      601 tgaaacagac gcgctttctc gaatagcaaa catatacaaa aaaatatcag agacaaaaac
      661 taatctcatc ataaacatta catatatttc tcaaaaagtt gttttctttc ttcaaaactt
      721 acttcacgat ggacctgatg aagcatccat aaataaccaa aaggatctct gaacattgag
      781 ttagtcacac caaagtccat catttctgtc atttcttgaa tctctacaca gccatttcgt
      841 aatgctttat tatctgtgtc ctcgatatca gagacgatga tattgaacca gatcgtattt
      901 ggatgttcag cagtaggagc agtcaaacca agagacgtgt tttcatccag catatggaat
      961 ctcgtgccat acaaggtaaa aatgacttca ttattgcctc tagggtaatc tgttgcctca
     1021 atcagttgta tttcatcaaa gattgtttga tacagttcta gtgctttcaa actatcattt
     1081 aatacaaaat ctatttccgt tcctttatgc ataaagatct cctctccttt tcagtcgaac
     1141 agttactaga ttcttttatt ataccagtta aagaaaacgc attcaaaaaa atagcggatt
     1201 tacttaccaa ctcattcgat tggatgataa gtaaatccgc gtcccattac ttctgctacg
     1261 ctgctgacaa tgacaaaggc acttggatcg atttcttcta tcaatggttt cattcgggaa
     1321 aattcatgat cagtcacaac gatcaataaa acctcttttg actttcgatt atacccgcct
     1381 tttgcctcta gcagggtaag gccacgtcca atctcagcac ttaagcgaag gcggatgtct
     1441 tccaaataat gttcactcat gaccataaca gatttctttc gattgatacc tgtttcgata
     1501 taagtcatga caattgaagt gattgcaata gataaaatag cataaagaaa ctcttctatt
     1561 ccaaaaacaa acagattaag agaaacaacg aatgcgtctg taaaaaataa gccaatcgaa
     1621 gtattcaagt ggaaatattt tttaaaaatg aggggaggga tcgtcgtacc gccgctagaa
     1681 gagttgtttt tatataaaat cgcaactcct aaagcaaaaa tcgcacttcc aaaaatgaca
     1741 gacaacaacc gatctgaagt aatcattgtt tctggaacta ttgcaatgat taaaggaaaa
     1801 aacaagcttc cgaaaagtac tttaaaaaag ggttttttac ctaaaaatag aagagctagt
     1861 accaacataa cgatattcaa cactaaaata actatagctc ggtcaaatcc taaaacagct
     1921 tccagtaata ttcctagacc gctgacacct ccagcagcaa tatgatgagg ccctaaaaac
     1981 atattgatag cgactcctaa tatgaagagg gcaaaaataa tcttaatgta tgtccatata
     2041 aattgtctcg tttctttcat ttatccactt ccttaattca ttaataatac tcttatctta
     2101 ttataactta cttttcacct taagttaact ttaattaata aaaaaattag gctagtctaa
     2161 attattatgt ttcattcttc tagaatatac ttctacgtta aaaactgtta aaaaactttt
     2221 actttagaaa attggagaaa ttgatcgctt aagataaatt caggacacta aatagtacag
     2281 gaagtagatt aaaactttta aaagttttaa gtctatctat ttggcaagtt taaaaaataa
     2341 aaattcggta tcaaaaaact gttaccgata acatttttga aagcgttgtc ttttgtttct
     2401 ctatcactta tagtgatgac gtcatattaa aacacaagga ggaaatcaat ggatacagct
     2461 gcaatttatc atcgaccgga aagtgaatat gcatttctat atacgaatac aagatttcgt
     2521 attcggcttc gtactaggaa aaatgatatc aaaaaagtat atgtgctttg tggagatcca
     2581 tataccataa caactgaaaa atggtatcaa aaacaacgac caatgaaaaa atgtctaagt
     2641 accaatgttc atgattattg ggaaattgaa gtgacgagcg aaacaaggcg cttacagtat
     2701 gcgttccatg ttgttgggga agataacacg gactgttttt acggtgatca aggaattttt
     2761 ccttatcgag aaaatgtgat tactgaacca aatttttatt ttcgaatacc ttattttcat
     2821 caaatcgatc gattcactat tccagaatgg gtaaaagaaa cagtatggta tcaaattttt
     2881 cccgaaagat ttgcaaacgg ggacaaagca aatgaccccg aacacacttt accttgggga
     2941 agtaaagatc cagaccgaga agacttcttc gggggagatt tgcaaggtgt gagggatcat
     3001 ttggattact tgacggacct tggcgtcaat ggcatctatt tttgtcccat atttaaagcc
     3061 acatccaatc ataaatacga tacgattgat tattatgagg tggatcccgc ttttggcgat
     3121 aaaaaacttt taaaaaactt gattgatgaa gcacataaaa gagggatacg tatcatgttc
     3181 gatgctgtat tcaatcatat gggtgtccat tcaccacagt ggcaagacgt tctcaaaaac
     3241 ggagaaaaat cgatctataa agactggttc cacatccgtt ttttcccagt agattcttat
     3301 cagatgactg acttaccaga aactgctgaa aatatcccat atgatacttt tgcttttact
     3361 ccattcatgc cgaaactaaa tacagcaaat ccagaagtgc aaaaatattt gctggatatc
     3421 gcaacttatt ggataaaaga attcgatatt gatggatggc gtcttgatgt tgctaatgaa
     3481 gtcgatcatc atttttggaa aaaattcaga gaagcagtta cagaaatcaa accagacatc
     3541 tatatccttg gagagatttg gcattcctct caagcttggc tgcaagggga tgaattccat
     3601 gcagtgatga attatgcatt cacagattcg attaaagatt attttgcaaa aaagaaaatc
     3661 acagcttcac aaatggtcag tggaatgaat catcagcaaa tgctttacag agatcaggtg
     3721 aacgaaggaa cattcaactt attagattct catgatactg ccaggatctt gaccctttgc
     3781 caaggtaaca aagaattgat gaagtctgtg atggccttta tgtttcttca aaaagggtct
     3841 ccttgtatct attacgggac agaaataggg atgactggtg aagatgaccc ggattgccgc
     3901 aaatgtatga tatgggagaa ggaggaacaa gatctagagc tattcggttt tataaaagaa
     3961 cttgtttctc taaggaaaca gttgtctaag attatttctg aaggttctac tcagtggcta
     4021 atagtatatg atcgtgaaga taagctctat ttcacacggg aactagaggg acagatcatc
     4081 tatgtttact ttaatcagtc aaaagaacct tgggtagtag aacaggaaaa tgaggtgatt
     4141 cttagtcaaa attgtcagtt gttagaagac gggaaagcag agatacgaca atacggattt
     4201 ttgatcatgt gttgaaaact gttaccggta acaacaagaa agcgtttgca aatgaagatt
     4261 tgtgcccatt ataataaggg tgtaacagca cgttgaatac acaggaggaa atgaagatga
     4321 aaaaaagaag tgtgaaacag ttgggtttag ggttaatctc tttaggaatc ttaggcggat
     4381 tagcggcttg tggcaatggt aactcttcag cagaagggga agccgatgaa ggaaaaacgt
     4441 taacagtttc cgttgattct ggatataaag attatataaa cgaaataaaa aacactttcg
     4501 aaaaagaaaa cgatgtgaaa atcaagctag tagaaaagga catgttcgat cagttggaat
     4561 cattagcgtt agatgggcct gctggaaagg gacctgacgt tatgatggca gcatatgacc
     4621 ggatcggtgc gttaggacag caaggacatc tggcggaagt aaaactggga aatgaagcag
     4681 cttacgatga aacagacaaa gcccaagtga cttatgatgg aaaaatctac ggagaacctg
     4741 cagtaatcga gacccttgtt ttgtactata acaaagattt agtcgataca gcaccatcaa
     4801 cgtttaaaga tttggagaat ctatccaaag acagtcgttt tgcttttgag tcagaagcag
     4861 gaaaaaatac aggattttta gctaaatgga ctgactttta ttattcctat ggtttaattg
     4921 caggttacgg tggctatgta tttggtgatg atggcacaaa tccttcagat atcggtttga
     4981 ataatgcagg tgctgtagaa ggaatctctt atgcaacaga ttggttcaaa aatgtttggc
     5041 caaagggaat gcaagacata aaaagtgcag gagacttcgc cagccagcaa ttcatgtcca
     5101 ataaaactgc agcaatcatt gacggtccat ggcaagcgca aacatacaaa gaaaacaata
     5161 tcaattatgg tgtagccaaa attcctactc taaataatgg acagccttat caaccgtttg
     5221 gcggaggaaa aggatgggta gtcagcaatt atgctaaaaa caaagacctc tctcaaaaat
     5281 ggcttgatta tgtaacgaat caggaaaatc aagaaaaatt ctttgaaatg gtaaatgaaa
     5341 tccctgcaaa ccaacaagct agggaaacag caaaggctaa aaacgatgaa ttaacaacag
     5401 ctgtgattga acaatatgaa acagctcaag cgatgccaaa catcccagaa atgggcgaag
     5461 tttggacagg tgcagaaaac ttgatgttcg atgcagcatc aggttcaaaa acaccaaaag
     5521 aatccgcaga tgaagcagta aaaacaatca gtgaagccat agaacaaaaa tactgattaa
     5581 aatgataacc gtccattttt ataaaaaatg gaacaggtgc ttcagataaa agtggcaaga
     5641 gcgagatgga aaattatctt gctcttgttg ccattatctt aaaagcagtt tgcggtttag
     5701 caagtttaga gggggcattc agatgcagca agataaaaca agcaatatca acgaaaaaaa
     5761 aatcacgctt tgttcactta ttccagggat ggggcagttt gtaaatggcc aagcttttaa
     5821 aggtatcgtt tttttcgcca tattcgtcct attcattggt cagatgcttc tgggcggatt
     5881 tcatgcattg gtaggattgg ttactttggg aagtatacca atggaagatc attcattatt
     5941 tattttgatt gaaggcactt tgcaattcat cattacaatc attttcttga ttttttacgg
     6001 tttgaatctt ttagacgctt atcgagtagc gaagatgcgt caagagggca aaaaaatcaa
     6061 tcggacgatg aaggaagtca tacataatat aggtgatgaa ggttttcctt atctattgac
     6121 acttcccgct tatcttctca tgatttttac gatcattttc ccagtcctag ttacattgtt
     6181 cactgcattt actaattatg acttcaatca tattccacca gccagtttaa ttgattgggt
     6241 aggggctaaa aactttttta gtatcttctt tttaagctca tatcgtaata ctttttttgc
     6301 agtcttttcg tggaccgtga tttggacttt atgtgcaaca actttgcaaa tcacccttgg
     6361 tattctcaca gcggttgttg ctcaccagaa atttattaaa ttcaaacgta ttttcggtat
     6421 cattttctta ttaccatggg cggtcccagc ttttattact atcatgagtt tttcgaatat
     6481 attcaacgat agcgtaggtg ccatcaatac tcaagtgatt cctttcataa accagcttcc
     6541 ttttgtagat atcagtgcaa tctcttggaa aacggacccg aactggacga aagtagcaat
     6601 tatcttagtg cagggctggt taggatttcc ctatatctat gtgatggtta caggaatctt
     6661 acaatcgatt tcagaagact tatatgaagc agcaaaaatc gacggagcaa atgcatggca
     6721 gcgcttttca aacatcacgc ttcctgctgt cttcctagtg gcagcgccaa catttattac
     6781 acagtatacg gggaatttca ataatttctc catgatctat ctgtttaaca atggtggtcc
     6841 cggaagcgta ggcggaggag ctggttctac tgatattctt atttcctgga tctataaact
     6901 tacgactgga acttctccgc agtattctat ggcttcagca atcacgttga ttatctccgt
     6961 catcgttatc tgtgtgtcat tgctggtatt taaaaagaca aatgcgttca atatggggga
     7021 ttaacaatga aaaaatttca ttcgagtgct cgattccaaa aacgactttc tcactttttt
     7081 acttactttt ttcttttaat actgtcagtc attatcatct atccgctttt gatcacagca
     7141 agtactgcct tcaagtcagg aaatattgca gcttttagtt tagatctttc aagtgactgg
     7201 actttaggaa actttactcg gctattcagt gaaacacttt acgggacttg gtataaaaat
     7261 acattgatca tttctgtcct aacaatgatc gtacaagtga ctgtagtaac tttggcgggc
     7321 tatacttata gtcgctatcg ttttatcggc cgcaaatcaa gtttgatgtt ctttttagtg
     7381 attcagatgg taccgactat ggcagcattg actgcctttt atgtcatggc tttcttatta
     7441 gaagcgctcg ataagtactg gttcttgaca atgatctata taggcggtgg aattccaatg
     7501 aatacttggc tgatgaaagg atactttgac actgtaccaa tagatttaga tgaatctgct
     7561 aaacttgatg gggcagggca tttcaggatt tttttccaga ttgtattacc gcttgtcaaa
     7621 ccgatgctcg ccgttcaagc attatgggct tttatgggac cttttgggga tttcatgtta
     7681 gctaagttcc tgcttcgaac acctgaaaat cagactgttg ctgtcggctt acaaacattt
     7741 atttctgatg tgacaaacca aagagtctct ctttttgctg ctggggcaat tttgattgca
     7801 ctaccgattt gtctattatt cttcttttta caaaagaact ttgttaccgg cctgacatct
     7861 ggcggaacaa aaggatagga gcagagtatc atgcaaacat ttccgttaaa ctatttttcc
     7921 gcattacgta cgccaactca agtgtttgcg ggacgcaaac tattatcatg gcctaaattt
     7981 ttcttgatat ttgtattttt agtttccttg atggtcatgc ctgtgactct tttttatgcc
     8041 aatcagatcc aagcgattcc attagaacaa tttctatccg ttcattcgct gatcgatgaa
     8101 caaggaaccc aaaaattttc tgaacttgaa ttatctgaaa ctgggttaca agcatcgcaa
     8161 caaacgatag ctgtgacccc tgaaattttg gtaggtgtgt ctttatctga gaaacaacaa
     8221 tccgatcatg gaacttttat tgattttgag aaggaacaat gggtgatcca acaaaaggat
     8281 aaatctggta tacgccgcta tacgatgaat tatagcccat ctttccaacc agattctgta
     8341 cgtacgcccg aagatttcca acgattttta gaaagagaat tttatgccag taatcgtcca
     8401 acaatcattt tatcttatag tttaagtctt ggtcttgtcc tatttgtcat gacgagtctc
     8461 attttattcg gggcttcctt tttcttgtgg atgacaagaa aaagccaact ttcatccatt
     8521 catacattca aagagagtgc aaatttgatg ctgaatgtta tgggaatagg ttccatggca
     8581 gcagcagttg tagggtttat ccactttgac tttatcttga tgctaagtgt ccaaacaacg
     8641 ataactgtct tgctgctttt atgggttttt gtcaaaacaa gattcaaaga taagcgtgtc
     8701 gaatgacaag tttaagcgat ttatgcgaca atgaatgtga aaaaaatgaa aaataaagta
     8761 gtttttgaaa aatttctgaa aaaattaaac ttcttagttg attcttttct tttttagtat
     8821 taacgtaata gggtagtttt tttaaggagg aaaatcatgt tagagaaaac tttatacaat
     8881 caattatttt cacgttcttt ctcgctccct gtcgaagtaa attattggga cggtacaacg
     8941 aaacaatacg gagatacgga cactcctccc caaatcaaaa tcaatatcca tgaagaaatc
     9001 ccaatgaaag agattacaag taacgcttct ttggcactag gagaagccta tatggatcat
     9061 cgaatcgaga tcgagggaag tatccaagca ttgatcaacg atgcttatca gcaagcaaac
     9121 agctttttac gaggaaaaga ttatctaaaa tggctgccaa agaaagaaaa acatacgaaa
     9181 caaaaaaaca aagaagatat ccatgcgcat tatgacttag gtaacgactt ttataaactt
     9241 tggctagatc caactttgac ttattcttgt gcttatttca atacacctga agatacgttg
     9301 gaacaagcac aaatcaataa agtccatcat atcttagaca aactctttat caaagaaggc
     9361 gaaacgttgc ttgatatcgg ttgtggctgg ggaacattga tgttcactgc taccaaagag
     9421 tataatgtca aggcaactgg gatcacacta agtgaagaac aatacgattt gattaccaaa
     9481 agaataaaag aagaacattt agaagataaa tgccgtgtat tattaatgga ttaccgcgaa
     9541 ctaaaaggcg aaacgtttga tcatatcaca agtgtaggta tgttcgaaca tgtaggttct
     9601 gaaaatcttg aaggttattt caaagtggta aaagatttat tgaaaccaaa aggaacagct
     9661 ttgatccatg gaatcagccg acaacaaggc ggtgcgacaa atgcttggat caataaatat
     9721 attttccctg gcggttatgt ccctggtgtt actgaattag ttgataatat tacaaaaaac
     9781 gatttgcaac tgattgattt ggaaagctta cgtcgtgact accaattgac attagaacat
     9841 tggacaaaga attttcatca agtccaagat caagtcacga aagaaatggg tgattccttc
     9901 tatcgaatgt gggatctata tttacaagct tgtgcagctt catttgaatc aagtaatatc
     9961 gatgtgattc aatatttgct tgttcaacct ggaaacaatg acatcccaat gcatcgtgca
    10021 taattgaggc aaaagtactg tttaaagact atttaaaaag aagctaagtt ttatgatgct
    10081 ccagaagtga acttttttgt ctaacttcta ggattgtctc taaagcttag tttctttttc
    10141 tttatatttt cataataaaa gtttggttct ttaattttta aacatgacag aaaatttttt
    10201 cttcgttata cttgtaatag aatactattt tataacaaag gggatcgaat caatgaaaaa
    10261 aactgttatt tatactagtt tatttgcagc tttgttttta gctgcttgtc aatcaaatac
    10321 caatcaaggc acatctggga atacgtcttc cagtagcgaa cagcgctctt cacaggtatc
    10381 ggactcctca acaaaagcaa gcacatcttc gtctagccag acaaaaagtt ctagtgaagc
    10441 aagtactcag tcagatatca aagtgtctgc agctcgtgcg atcgaattgt tccaagataa
    10501 atacccagat actgcaatta ctagtttgga attagatagt gattggggat cttacttcta
    10561 caagatagaa ggtgtcgatg atcaaaaaga atacgaagca agaattgatg ctcaaaatga
    10621 aaaaatggag acagagaatc cagaaactct agatcgagat gaacaaaatg gtcaaaagaa
    10681 aaaagaagat ggtctggatg ttgataaatt gatcacgatt gaggaagcag caaaaatcgc
    10741 cgtcgacaaa gtaggaagcg gtacggcaac agattgggat ttggataaag atttaggtac
    10801 tacttattgg gaagtcaaag taaaagacgg caatcaaagt acatcagtca agatcaatag
    10861 ccaaacaggc gaagtactgt caactgaaca agatgattaa gaatttcttc ggaaaacaag
    10921 agttgatttt tcttttagtc atgatacact agacaaaata acttgtttga aggagcgatt
    10981 tacttgagtt tagaaacgac ctttgccaat catatctttg ccaatccttt gatgaatgca
    11041 tctggtgtcc actgcatgac tacccaggaa ttagatgaac tggctcattc agaagcagga
    11101 gcatttatca ctaagagctg tacgatcaat gaacgaaaag gaaatcccga accacgctat
    11161 tttgatgttc ctttagggag tatcaattct atgggacttc caaacttagg tttttcttat
    11221 tatctagagt atgctcttgc gtatgaaaaa gtgcaggaaa accaaaatca accgttattt
    11281 ttttccattg ccgggatgag tgtccaggaa aacttggaaa tgcttgagaa aatagaaaaa
    11341 agtgggttta atgggatcac tgaattaaat ttatcttgtc ccaatgtgcc tggaaaacca
    11401 caactagctt acgattttga ggccacttat gaaacactga aagaagtatt cagcatcttt
    11461 tctaagccgc taggaatcaa attgcctcct tattttgatt ttgctcattt tgatcagatg
    11521 gctgatatct tgaatcagtt tccattgacc tatgtcaatg ctatcaacag tgtgggcaat
    11581 ggtttgtata tcgatacaga acaagaagca gtagtcatca aaccaaaaga agggttcggc
    11641 ggcattggcg gagagtatat caagccgact gctttggcga atgttcgcgc tttttataca
    11701 cgtttgaaac cagaaatcca aatcattggt acaggtggga ttcggacagg acaagatgca
    11761 tttgaacatc tgctatgtgg cgcaagcatg ttacagattg gtacagagct tcataaagaa
    11821 gggccggaaa ttttttctag aatcataaaa gaattaacgc agattatgtc agaaaaagga
    11881 tatacgtcaa ttgacgaatt taaaggcaaa ttacgcacca tttcatagca aagagacgaa
    11941 ggtcatgatt gatcttcgtc tttttttata aaaaacactc gtctgttcat tcctgtgcaa
    12001 gcgtactcat tgtatgttag acgaacttgt gggaaaataa cagaggcaaa aaggaggata
    12061 atatgaatga tgcaacagaa ttagcaaaag agcttaaaga aaaagaattt agttttcaag
    12121 aactagttac ggatatacag aaaaaaataa agaagcaaaa tcatgaattg aatgcgtttg
    12181 tcgcgcttga accattcgag agtaattccc acgagctatt gattccccag tcagaaaaag
    12241 ggccattggc tggtatccca tttcctttaa aaatgctcgg tcaagaaaaa aagggatggc
    12301 tagctacttc aggatctcgt ttatttgaaa cacaccgagc ttctcataca tctaattatg
    12361 tgcggcaagc agaagcgata ggtctagttc cttttggaca aaccaatgcg ccagagtttg
    12421 gtttcaaaaa tattacagac ccagtcatct atggcccagc aagaaaccct tggaaccttg
    12481 aatgtacacc gggcggatca agtggaggag ctgctgctgc agtttcatca ggaatcgttc
    12541 ctttagctgg tgctagtgat ggcggtggtt ctattagaat acccgcttcg ttttgcggat
    12601 tgattgggct gaaaccttcg cgagggacga tgccagttgg tccatatgct tggagaggat
    12661 ggcaaggagc tgctattgat ttcggcttga cagtttctat gagagacacg gaggctttat
    12721 tttatgggat gagaagtatc cattccggtg cgccatatca agtatcgcca gttgagtggc
    12781 aaacacatcc aagaaaaaaa cggttgaaga tagctttttg tgttgattca ccgatccact
    12841 cacagattag tgaagaggca gtacttgctg taaaaaaagc tgtagatttc cttggaaaag
    12901 aagggcatga tttgacagag attccttacc cactagatgg tcgtaaactg atcaggtctt
    12961 attatcagat gaatggcgca gaaacagcag caatgatccg ctcgattgaa acaggcatcc
    13021 agcgagctgt cagaaaagaa gaacttgaac ccatttcttg gactttgttc caatatggtc
    13081 agaagctctc tgccgctact tacatcgatt ctctgcatgt atgggatgaa gcagcaattg
    13141 tcatggaaaa cctacatcaa gaatacgatc tattcctttc accaacgact gcatttaccg
    13201 cccctaaaat cagcgaagat ttgcaaagtg atgcgataag agcacagatg gaacacatca
    13261 gtgattgttc tgaagtagaa ggtttagacg ttgtttcttc catgtttgag gagagcttga
    13321 agatcacacc ttatacacag ttggctaatc tgactggaca accagcaatc agcttgccta
    13381 ctcatttgac aaaagaaaac atgcctctag gaatccaatt tatggctgcc agaggaagag
    13441 aagatttgct atttcaaatc ggctatctat ttgaagcaaa tcatcagttc catttaccaa
    13501 atccatggaa atagcagaaa caaggagaag aagaatgaag aaaaaaagat tgtttgctct
    13561 aataactagt gcctttttta ttttaagcgc ttgcggtaca gctgccgcta atcaggaaga
    13621 taacagctgg agtaatgtag aaaaaaagaa agaattagta gtagcgactt ctggcacact
    13681 gtttcccgca tcttattata atgatcaaaa tgaattagtt ggttatgatg tagatttggc
    13741 aaaagaggtg gctaaacggt taaatgtcaa aatctccttt aaagaataca acgtggatgg
    13801 acaaatcact tctgtttcaa aaagagaatc agattttgct gcgaacgatt ttggtatcac
    13861 aaaagaaaga gaaaaaaaat tctccctttc agagactttc aaatattcat ttgacagtat
    13921 gatcgtacga aaaaaagatg attcaggaat ccactcactt gaagatctta aagggaaaaa
    13981 agcagctggc gaacccaata ctagctatat gcgtttagcg gaaaaacacg gagctaaatt
    14041 agtcacatat gacaatgcca cgaatgatca gtatttaagc gatgtagcaa atggtcgaac
    14101 agatgttatt ctaaatgatt attatctgca gaaaatggcc gtatctgctt taccagatat
    14161 ccctgtaaaa atactggaga acgtttattt caatgaaaac gaaagtggtt ttttattgaa
    14221 agaaggaaat gatgctctga aaaagaaaat cgatggcgta ttaaaagaga tgaaagaaga
    14281 tgggacgaca aagaaaatat ctgaaaaata ttttcaaact gatgtttcag tcaaaccgaa
    14341 agaaacgatg gctgagtcgg tgagtgagtg atgtactttc ctctaattga tttttccctc
    14401 atgtggactt cacttccttt cgtactgcaa ggcttggtat acacattagg gattggcttc
    14461 gtgtcgtttc ttttaggaaa tttggtaggg ttgcttttga cagttttagg tcttttggat
    14521 tggctgcctc tgaatgtatt tattcgtttt tatttatcgt tctttagagg cattcccgca
    14581 ctagtcctgc tgtttctgtt atatttcggg ttaccttatc aattaagtgc cttaacggct
    14641 tcagtcatct gctttacgat taccagcagt gcatttattg gtgaaatcta tcgaggatca
    14701 ctagcaggcg tttcttcagg tcagtgggac gctggtttag cttctggttt ttctttcttt
    14761 ggggtattga aatatatcgt tttgccgcaa gcttttcgaa tctcagtacc ggcactcagt
    14821 aacgtagcta tggatctagt gaaaggtact tcgttagcag caacaatcac agtgccagaa
    14881 atatttcaaa aagcaaagat cataggcggt cggacattcg attatttttc tctctatatt
    14941 ttagttgcac tgatttattg ggtcatttgt atcgggatcg aaaaagtgca acagtattta
    15001 gaaaaacgtt ctatccatca gtcaatctga aaaatagaaa tggtgctagc gtggctggca
    15061 ccatttctat tttttgtttc ttgtatattc tgcctagtat tttaaaacca tttcatgtaa
    15121 aatgtaaatc gaaaatatgt tcggaggtag aaaacatgaa gaccccgcta accatcgaaa
    15181 tagaatcctc gttataccaa tattgcatcg agcaaggcgg cttggttgta gaagaagtca
    15241 cgatgcctga tgaccaagga attgtagata cgcttagctg cttgacaaaa tttgatggaa
    15301 gccgagaatg gcgatgctat gagctgaaag tgacaaaagc agattttcgc tctacagcca
    15361 aactgtcatt tgttggacat tataattatt ttgttttacc aagtaaacta tatgaagaag
    15421 taaaaactga aatccctaca ggaataggtg ttttagtgta tcgtccgtac acggttgaag
    15481 aggagatgcc tgcctctggt acatttctga ttgcgaaaaa agcagcaaag aaagagcttg
    15541 ctgtaccgga agaagctttg acaaaccgct tcatggcttc tttattcagg gaagtaagaa
    15601 aagcaaagca aatggagcga ggcgtaaaat attttccaaa agatcaattg tacaaagaat
    15661 tgaaaagacg ttcagaaaat caagatccat tttctaacga acgatattat gaacggtttt
    15721 tagaggaaat agctagtcag gcaatcaatg agttgcaaga agaagttatc gcgcttcagc
    15781 atgattatga atatttgagg caacaacagc agatccgtcg gttgcctaca gagccattgg
    15841 agtgaaaaat atgtactatc cttatttaag aggaaaacaa tttgacctat tagcattaaa
    15901 agaagcactg tcgcgaggat tgctctccaa taaaatccaa ccagtgatcg aaccagtacg
    15961 tgattccgct acgcttaaaa atgtgatcga attatttcaa aaaaagcacc atccaatcgc
    16021 tgtgatccaa aatccccaag taggacaatt caaattattc gatcagcatg tgcacagttg
    16081 gacagtcaaa gaaaatagct ctgtcgtccc tgcacagatc ttaacgccag aaaatctcag
    16141 tgaagtactg gattcacctc cagcgtttct tgttttcgat ggacagcact acccaaaaga
    16201 tacagaggtg tggaaacagt tggcaggagt tgattcgaaa tttttgatac cagatactag
    16261 tcgctttcgc atctggctgc ccgaaaacaa aattgtgatc cgtgactctt ttcaaacgag
    16321 aaagcatgtt gaaagttatg cagataaaac agatgacttt tttagtgatg actatctttt
    16381 tttccacgca gacggatata ttggattttc tgatttcacg atcgaaggta gccgttattt
    16441 cgataaaggg ttccctagcc gagcgcttgc tatccatcta acgtatattg atgcttacgg
    16501 caatatacgc gtgaaacatt ttgtctctga cagtaacgac tctgctaaag accaagcatt
    16561 gaagtttctt gaagcaggag ataaaatgaa aaaatggatc atgcgtcacc atcatcaact
    16621 cttgattact tcaggaatga ttgaattatt ggctctttac cagcaacaaa aattccctgg
    16681 actgggagtg ttgaaaaagt ggtcacttat gcatcatttg gaacttatta gtcacctgct
    16741 agatcatcca aaagattggc ttaaatatta ttcaaaagtt caggaactat atgaagtgat
    16801 ccaatgatta gataatgtaa atgaaaaagg aatagaaaag aggaaactgg atgtatattc
    16861 ggcaaacaag gaaagaagaa gtagaagaag tggtagaaat cattaatgcc gcagcggatt
    16921 tcattgcttc gcaaggctct cctcaatggc aaaacgggca gaaaccaaca aaagaaacga
    16981 ttttgaacga tattgaaaga aaagaaagct atgtattaat agtggaagat caaattgctg
    17041 gaacagctgc attagtctca ggcgtggatc ccgtttacac aaaaatagat ggtagttgga
    17101 aagaatcaac tggtccttat ttatcgattc atcgtgtcgc tttagcagaa agtactcgag
    17161 gaaaaaaact agcaaaaccg ttcttagaac atttgttgac gattgcagcc agcaaaaata
    17221 tccaagatat ccgtatcgat acttatccag ctaatgaacc gatggaaaag accatctatt
    17281 ctgctggatt cacttatcaa gggatgattg aatttccttt tgaacacggc gaaagaaaag
    17341 catatcaaat aatcatcaat tgactataaa atcatctgag caaagataaa gacattaaca
    17401 ctactgaaaa aaacaatcat atgatagcca agaggttgta acagaagtgg ccagcttcaa
    17461 aaaacaagaa agaatttccg aaaatgcttc tcaaattttt gtggaatttt agcgtatttt
    17521 acgaaatagc tgctttctga aactcccttc atcgagaggt cgtgacatag cttttgtcac
    17581 gatctctcgg cttatcctac gagtattatt cgatacattt atatcaataa tccttttttt
    17641 attttatctg cagcttcttg gaacgctcca tcgtttgaca cgactaaaag tgaggggata
    17701 gctttcaaac gtttcaactg tgctaaatct tctacataaa ccgccagtct ggctgaaatc
    17761 tgttcagatg aatctccacg ttttttcagg cgcgattgca atgtttcttt agagatcgta
    17821 ataaagatag gacggactac cgtcccgaaa tactcatata aatgccaaaa accatttgct
    17881 gtcaaaacgg cgtaacaatt tcctactgtc agtttctttt taatttctgc tttactggaa
    17941 ccatatttat gttgagcata ttggtcccac tctgcaaact catttccctt gatcatctga
    18001 ttgaatgtat tgtcagaaac aaaataataa tcctcttgat ctttttcccc aggtcttggt
    18061 gatcgattcg tgtaagtaat gatcttttgt tccggctgaa aaatagcttc tgcgagtgaa
    18121 gtttttccag aaccagaagg accgataaat acatagcaat aattcattgt catttctcct
    18181 ttgatgattg aacaagtgaa aaagctttgg aaaatatttc caaagctttt aaaagtaact
    18241 ttgctttttt gtattttata ccagcaagcc agtcacaata gcacttaaaa agctgactaa
    18301 agtcgctgtt agcaaaattt tcaatccgtg ttttgcgaca agatttcctt tttcttcatt
    18361 taatcccttc atcgcaccag aaatgatccc gatagaagag aagttggcaa atgaaacgag
    18421 gaagacagat ataattgctg ttgtacgctc agtaaaatgg aaattaccat ttgctaattc
    18481 tgtcatagca acaaattcat ttgtaaccag tttagtcgcc atgatactac cggcatccac
    18541 tgcttctttc catgggattc cgctgatgaa ggcaagaggg gcaaagatgt aacctaggat
    18601 ctcttggaaa gtgatgccga atatcccgtg gaagatagca ttgatcatgg caatcaaagc
    18661 aacaaaaccg ataagcatag cagcaaccgt gatcgccaca tggaaaccat caagaatgta
    18721 ttctcccaac atttggaaaa atgtctgttc tttgttttct tcaatgatca gctcatcttc
    18781 tttttcttct aatacatagg gatttacaat tgaagccaga atataaccgc caaataagtt
    18841 caaaacaagg gcagtgatca catatttaga atcgatcagt gccatataag atccgacgat
    18901 cgacatagaa actgtagaca tagccgatac actcatggtg aacaaacgtt tctcagatag
    18961 gaagggtaat tcctttttta tggaaataaa aacttccgat tgtcctaaaa tagcagaagc
    19021 tactccatta taagattcca atttgcccat cccgttgatt ttacttaatc ctagaccaac
    19081 agctttcata aataatggaa gaatcttgat atagcgtaga ataccgataa tagcagaaat
    19141 aaatacaatt ggcatcaata cggaaagaaa gaaaggtgca cttcctttat ttgctacacc
    19201 ggcaaaaaca aagtcaacac cttgcccagc aaaagcaaga agatgatcaa acatttttgc
    19261 caatacagaa acaaccgctg taccaaaagt tgtacgtaat aatacgaaac caagaacaag
    19321 ctgtaaaacg aacatcacaa ttagtggttt caatttgatt gcttttttgt tactgctgat
    19381 caaaaaagca agccctaatg tgacaaataa accaataata cctaataaat aactcaaata
    19441 atcactccta ttccaaattc cgttttattt tacctgtttt gcaaataaaa tactaatctt
    19501 tagtgaaatt ttcattactt ttttagagtg aaacgcattc attttccatt agaaaataaa
    19561 gcgaacaaaa taaaaggttt aaaaagtgta acgtcttagt aaagtctata aaaaaacgaa
    19621 actatcgatt aagctaatag tttcgttttc aacatttata agtaaacttt ttctattggt
    19681 aatatagatt ttcggaaggg tagacaggtg cgcaggtaat atcgattcct agttttttca
    19741 atgtttgttc atcattttta ttgaccatca cagtagagtg ggcttgtgct ccctcaagtt
    19801 cagctagttt atcataagca acttgagcga ttggattcgt tactgcactg attgataaag
    19861 cgatcaagac ttcattgatg cttagtgcat ccaaagagga atgaagtgtc tttgatttca
    19921 atccttgtat tgtttcaaga actaatggtg acaataaagg aatgtcatct gcgatatggg
    19981 ctaaatgttt tactgcattt aagataactg ccgctgacgc atccatcaat gaacttgtac
    20041 gcccggtaat gatgacttca tctggtaatt cgattgcaat cacagcagaa ggatcttttg
    20101 taggactttg cgcttgaatc ttatctgcat agtcatgggc agggactacc acgtttcggt
    20161 cttcaggacg taaaccgact tcttccataa tcagtttgat tcgattaact gcttcttcgt
    20221 cgatcaatcc ttttttgaag tcgcattctg tttggaaata acgacggatg atttcttgtt
    20281 tagaggcttc ttggacaacg gtatcatcca cgatcccaaa tcctacacga ttcacaccca
    20341 tgtcagtagg agattgataa acagattctt taccagtaat tttttcaata atacgtttga
    20401 ttacaggaaa tgtctcaaca tcccgattat agttcacagc tactttattg taggcatcaa
    20461 agtggaagga atcgatcata ttgacatctt ttagatcgac tgtggctgct tcataagcaa
    20521 tgttcagcgg atgtttcaac ggaacattcc atactgggaa agtttcgaac ttggagtaac
    20581 cagctgcatg tcctttttgg ctttcatgat acagttggtt caagcaagta gcgagctttc
    20641 cacttcctgg gccaggagct gtcactacaa cgattggttt agttgtttca atatactcat
    20701 tttttccaaa accatcttct gagacgattt tttctacgtt gactggatag tcttcgattt
    20761 ctgagtgttt atagaccttg atgtttcgtc tttctagttt attgataaag actttcgtgg
    20821 caggctgtcc actatagcga gtgataacga cactgttgat taataagcca taaccacgta
    20881 attcatcgat taaccgcaag atatccatat cataagtaat cccataatca ccacggatct
    20941 tattacgttc aatatctcca gcatagacgc aaatcagtat ttcagcttga tctttcaatt
    21001 tttgcagcaa tttgattttc gcatcttctt caaatcctgg aagtacacgt ttcgcatgct
    21061 tgtcgtcaac taacttccca ccaaattcta aatataattt gtcatagtgg ttcactcgtt
    21121 ccaaaatata cgctgactgc tcttcaatat atttttctga atcaaaacca atttttttca
    21181 ctaggttccc tccttaagta ctaaagcatt ttttcatttt tttgaggatt cgtcaactgg
    21241 aagagcgaaa ttcctcaaaa aaacaaagaa aatggtttaa accaacttgt ctagatagtt
    21301 attcattggt atgatagttt ttgataagga aggtgctaca tgaaaaaaag acagaaaaag
    21361 aaaaacgcat ataaacacta tatccgttcg atttttaccg gttatgaaag aatgcttgaa
    21421 gatcccgaat tggaacaatt gacgtttact tatctaaacg aagaaacgca gctaactcgt
    21481 gatgagcatc agcgcattca tttcacaaca agagatctgc ctagtaaata aaaaataaga
    21541 taaaggtcat cggattcgat tctgtcctat cagatggaaa gactagttga tcgaaaaaaa
    21601 ggctgtacca aattttggtg cagcctgttt tatggagcat tgcccgctct tttttataac
    21661 aattttttac agaaaatggt actattgaag tattaataag tgaaaaacag atgagtaaga
    21721 ggaggcaagt agtatgaaag agccagatac aaatgcaaat tatgagccag acgaactaga
    21781 ggagacgaac gcggatcagg atacaggaca agaatcgtct tctttttacg atatcaaaga
    21841 aaaagcaagc atgaatcttt cccaattatt agaagactta caggcttttg aaaaagctgt
    21901 ccgcgaagaa gatatccctg agatctaccg tttatacaat ggccgattga atgaagaatt
    21961 aaaaagaagc tcaaatgaaa atcacgagat cgatcaattg ctgatgcgta agatccatga
    22021 tcgtttttta caggaatttc cttttatgga acaagtagaa aacatctcgc caacgatgag
    22081 ctattacaaa atcggcactt attaccatga tcggcccacg gtcggtattg atgcaagtct
    22141 gccagaaatt tttgttttgc ctaagatcga tgaagagtgg gagaaatatt cccaaccgga
    22201 gtcaacggac tatgacaaaa aaatcaatga gctagacgca aaggtgatca ctgctcagac
    22261 agaaattgaa cgtttagatg aacaaataaa agaaatcaat cgacaaatga ctgatttgaa
    22321 cgacaataaa ggattcttga atcgtaaaaa aatcgaggaa gaaattcaag aattagagaa
    22381 gaagaagcaa gtactatcta atgaaaaatt aggctggctt ccttatattg agacgcctga
    22441 aacaatccag cagcaaaaag aagcattgaa gcaagaagca agagcagacc agcttcgtgc
    22501 agccatcgta gaaaaagaac aaaggcaaat cagacgctat ttcggtagca aagagggatt
    22561 cggtcaagca atccatgaat tcttgatgaa ttatcttggc aatgagaatc ctaataatca
    22621 atctaatgaa ggaggttccg agtatgaatg aacacgatga agcagaatgg acaaaaaatg
    22681 aagaacaaac agaagatcat gaagaaacga acacttcatt ggaagaacaa acaagtaatc
    22741 ctctggatga cacagaagaa atccctatgc tagaggaaac aaaaatacat gaaaaagaaa
    22801 aagtaactcc gacgaatacg aatactgcag aaaacaccca tgcttacgaa ataactgaaa
    22861 atcccgggta tttagaagga aaagagcaag atcatcaaga tatcgtcagt ttgattgaaa
    22921 cagcggaagc agaattagcg gatttacgta tgagaaaaga tttgatcgaa tcagattttc
    22981 cacaattatt agaatcatat gatcgtttta tattgaatga agaaccaatc tccacgatcg
    23041 gaaagacaag cctgatcgaa tacttcacgt atgaattact gaaaccgttg aatgatattg
    23101 gtctggaacg gtcaaattca gcttatgaca catggaaaac aagacatttt tcgatcaatt
    23161 atacgttgaa tggacaaaac gaattagtct tttcctttgt attaccgacc atcgatcaac
    23221 gataccaagt ggaatcgatg agtctcctaa acgtatcacc agagacaatg gaaatcaatg
    23281 tccaagatga ccgggtgctt tctttgatcc gacactggtc agtggatcga gtattctctg
    23341 cagggcagat cacgatattc aatcacaaat tgaatcaatt attagcccat gcaagaacac
    23401 ttggttttac cgttaatcag acattactag acaatacgaa gccacttcgt ttgaatcttc
    23461 agagcgaatt tgaattgacg aatgaagtat tggatgatat ttttatcgtg gcaatgaaaa
    23521 atccatccta cgatatggaa aagatcaacg aaactactta tcaagtacga ttagataaag
    23581 gacagtcttt aacgataaca acaaacgaaa aagatcaaac agtcttgtcg atctcatctg
    23641 gagactaccc acgatctgtc attgatttct ttatcaatta cgaattcttg gtcccattaa
    23701 tggtgagaaa gtcctgattg gataagttgg attaccagat gtcattcaga taattctgtt
    23761 ccaaaggact tgcggcagtt atccagaata attgtcacaa gtcttttctg tatgtactaa
    23821 atggacgtga ataacttgct gatgaaggag ggatttcatt aggaatgtcc acaaataaaa
    23881 tagcacagct tagcttattg tctgctgctt gtgtagcagg taggatcgct tttcaattta
    23941 ttccgaattt ccagccaatg actgctattt ttttatttat agtactttac ttaagcttaa
    24001 aagatgcgtt aattgtcatg agtctttcta ttgcgatcag cagtttttat tttggtgttg
    24061 gaccatgggt catcggccaa tggatcagct atactgttgt tctgagtttg ttttcaatcg
    24121 tctgcttgag aaaaacagtg caaaggaatc tatggttaaa gggagtctgt ttttttctgg
    24181 cgggcatggt ttacggaata ggtatgaccg tttttgatac gctgttatat cgtttgcctc
    24241 aaccttggat ctattacctt caaggggtgt cgtttgattt gatgcacagt ataggcaatg
    24301 ttgtgttctt tcttgttttt ctgccagtcg tcaaacgttt ttacaatcat tcaggaggaa
    24361 aaaatgaaaa aaataattta tagtttgctt gcaatgagtg tcagtatact cattttgaca
    24421 agttgcagta caacctatac acaatcggct tccaaccaaa aggaggaagt aaaaacatcg
    24481 caaaaagcaa caatcacgtt acaagaaaat ggtcaaaact tttcggaaaa agaagtggtc
    24541 ttcaaaaaag gcgatgattt actgagtatt ttgaaacgaa attttgaagt caaagaagat
    24601 aacggcttca tcacttcgct tgaagggcac tcacaggatg agaaaaatca actctattgg
    24661 atgtttactg tggacgggaa aagtgctact actggtgcca aagagatcaa attgaatgat
    24721 ggacaatcgg tcattttcaa tttgtctaaa ctataagttt cataaaaaac tgttaaaggg
    24781 cgaatattgc cataattcag tgagttcagt tgatgaaaga aggaaaataa catggaaaat
    24841 tttaaaaaaa gcggaatgtt ttccgtaatt gctgctctag gggctaatat tctagttgct
    24901 atcagcaaat ttgtcggcta tgcaatcagt ggcagtgccg ccatgctaaa cgaaagcatc
    24961 cacagtatcg ttgattgcag caatcagatt ttgctgttat tcggtgataa acaagccaat
    25021 aaaggacaga gcgagttgca tcaatttggt gaaggacgag caaaatactt tttcagtaca
    25081 atcgtcgcaa tgatgctttt cttcggcggt ggggcacttg gggtgatgga agcttttgaa
    25141 aagttgacgc atccatccca tgaagtgggt aatccgatca ttgttatagc aatactgtta
    25201 tttggtttgg taatcgaagg aagttcgtta cgcgtggcaa tgaaagaaat caaagaattg
    25261 aatactgaaa aactttccac gatgcgcttt ttgcgcgaaa gtcgacacag tgaaatactg
    25321 attattttta cggaagactt gtgtgctgta atcggtttgg tcttggcttt agcaggaaca
    25381 atattgactt atgcaaccgg gattgctgca tttgatgcga tcagcggatt gctgatcggt
    25441 ttcttgctga tgggagccgc cattttccta gcaaaagaat tttatagtct gatcatcggt
    25501 gaaagcgtga cagcaagcga tttatcaaaa atcaagttag cttttgaacg tcctgagatc
    25561 agtcggctga tcgatataaa aacagttcat ttaagtccaa cggagatttt agttgcagca
    25621 aaagcagata tcgttggtaa caaagagaat gaagcttact cggtcatcaa tgatattgaa
    25681 aaaaatatgc gtcagtctct tcctgacaag aagatgtata tatacattga aacagataaa
    25741 tatgacccaa attattctcg taaataaaac gtttattcat gaattgaagc aaaaatgaga
    25801 aaaatataat cttgttttta aataaaacgg ctacaattta gcgaatttat gttacaatga
    25861 gtccgctgtt tatttgttgt aattaaagga gatattttaa tgaacaaaaa gaaaagtgcg
    25921 ccatggcttc aagctttgca tgcagtgatg ccactttgta taagctatat accagtagga
    25981 ttagcttgcg gagtattgtt gcaaaaagtt ggatttgatc ctctcttatc aggactgtta
    26041 tcgattctgg tcttttccgg tggcgcgcag tttttagttg catctatgct tacgacgcaa
    26101 gcatcatttg caacgacatt attgatggtt ttctttttag aattacgcta tacattatta
    26161 ggagcaagtc ttgccggttt tatgaaaaaa gaaaagcgga cgtttttggc tgtcttttct
    26221 caatcactga atgatgaaaa ctatgcggtg aactacttaa agttttcaac tgacccttcc
    26281 tggaataaaa gaaaggcttt atatgtcaat tggttctcaa tgactgcatg ggccggtagc
    26341 aatatgatcg gtaatttttt cggctcggtg attcgagtag atgctgacct tgtccatttt
    26401 gctttgacgg ccatgttcat tttcatgttt atcatgcaga tgaaaagcgc actactgatc
    26461 tttacaggtt tattctcagg cgtattaggg gtcgtattca tggtattttt ccaaaatact
    26521 ttcggattga ttgcagcaac agtcattgct tcatttgccg gatttatgct ggagaaggca
    26581 ttcaaaaaag aaaaagctaa gaaactaaga gaccgcggta aagatgtcaa tgagccgctc
    26641 ttcaacttcc cggaacagga ggccaatcac catgactaaa ctatatttgc tacttttagt
    26701 tgcttgtctg ttcatcgtgg catatatccc gcgcttgttc ccgatgcttt attttactca
    26761 tcgaaaagtg ccatcctggt tcagtgactg gatgaaatat gtaccggtgg cattatttgc
    26821 ggcgttagct tttaaagatg ttttcattac tcatgaacat ctggatattg cttggaatat
    26881 caaaatagct gcaatgattc tagtagcagg cgtggcttac aaaacacgtt cgatggcgtt
    26941 gtcagttttg acaggacttg cgtctgtctt tttgctgtct atgctttaaa ctgttttatt
    27001 ttattaaaaa cagagattgc gacataagtt gttcaaactg atctatccga actgcatttg
    27061 caacagtcaa ttctggatgc aagtttattc gtagggataa aaaagattag tgttggctta
    27121 tgatgcaagc tcttttttat tttaggaatt agagagggat ttgtccttct atgatttttt
    27181 gctataatag ggaagatgtt tattttatga aagaatagtt gagggaattt aaatgaataa
    27241 aaaattgatg caaggaacat tttggctaac ctttgctaat cttctatgta aagttttagg
    27301 ggtagtctat ttgattccct ggctaagtat gatggggaac aatcaagatg gtatgcttgc
    27361 tacgacattg tataatgttg gctatcttcc ttatggattg ttcctgatgc ttggtacagt
    27421 cggatttcca aatgcgattg caaaaaaagt agctgtagcc acaaaagaag gagataacgc
    27481 tgcttgtcgg ctgattttta gaagtacgat caatatcatg tttgtcatcg gtatcgcctc
    27541 tgctgcactg atgtatttat ttgctccttt actagccgga atcagtccga ttgctaacgt
    27601 taataatggg atactagcta tcagaagttt atgcccatct ttgattgcta tcccaattct
    27661 tagtgcaatg agaggatatt tccaaggaaa aaatgatctg cggccttatg gaacttcttt
    27721 gattatcgaa caggctgtgc gagtgatcgt tatcttggct ggtacttatt acttgcgcgt
    27781 attgactgac ggaaccatat tagaagctgt attgatcagt acagtcgctt ctttcttcgg
    27841 tgggttagct gcgattatcc atatgtatat cgtcggacgc agaaaagact tcttcgaact
    27901 taaagatttt ttgatttcca gccgttattt cgaaagagaa aaccgatctg cctctgtctc
    27961 tatcattcgg gaaacactac cgtttatttt tgtcggctca gtcattacta tcgttcaaat
    28021 gatcgaccaa gtaacgatga aaccactgct tcactttttc cgtccagaga tcgcagatca
    28081 gcaactggaa ttcttattca gccgtgcttc tgtcaatcca aataaattga cattgatcct
    28141 gatctccatg gtaggaacag tagctataag cagcttgcca atattaagca cgatgaagaa
    28201 aaaagatcgg atacaaatcg aaaaaacagt aggagatagt ttttcgattg cgttattgat
    28261 tcttcttcct tcattgactg gaatgtcttt attagctgga ccactataca cattgttttt
    28321 tggctatgat cctgaaagtg tcggatattt ccaaatggct ttgctagctt ctttgttttt
    28381 ctctttattc acgatcctat ctacgatgct tcaatctttg aatcaccatc gttttgcgat
    28441 ccgattaact gtagaagcaa ttatcctgaa agtcatcttc caagtaatcg gattaggatt
    28501 agttggcgga tacgggatga gcttatcaaa tggcttagca ttcggtattg tctttgttcg
    28561 cggctatcac tttatgtgca aagaataccg aatagcacct ttagcaaaga tcagcaattt
    28621 tttcttaaaa actttccgct ccaccctgat tatgcttgca gtatgttttg ccgttttctt
    28681 tttgctgaat cagcgattgt caatggaatc aaaaagctat gcaatgattt attgtgtggc
    28741 tgtaggaagt attggcggct tagtattttt attttctcaa ttcggaaaaa atgggtttcg
    28801 aatgttgaaa aatgttaaac atcatagcag aagcaaagaa taggttaact aatcgttttt
    28861 tgctgtcact tgaaaaacgg caactcgtat gattacgctt gtcgtttttc tattttccaa
    28921 ttttagtttc atatctaatc ttacttatga tatagttata aggtctggaa aaattctttg
    28981 aaacgaggaa attaaacaca tgaaacttgc agtagttaca gatagttcgg catatctgcc
    29041 ggaacgtatc aagaaccatc ccgacttatt cgttattcca atccctttga ttatggatgg
    29101 gaaaatttat aacgaaggaa tcgatatcga agcggatgaa tattatggac ttttaaaaaa
    29161 cagtaaagat tttcctacta cttcacaacc tgtcgtaggg gaagttttgg gtttatatga
    29221 ggaattgaaa gagaaagggt atgacacgat tttaagtatc catctttctt cagggatttc
    29281 tggctttgtc aacacattat ttgcgatgaa agatgacatc agcggagtaa cggtcattcc
    29341 ttatgactct aagatcacta gtatgccgat gggacacatg gtagaagctg ccttagactt
    29401 aaatgatgaa ggtcagtccc ttgatgaaat acttgcacat atcgatcgaa tccgagataa
    29461 tacctatgct tatctgattg tagatgattt gaacaattta gtacgaggag gacgtttgac
    29521 aaatggtgca gcgctgattg gcagcttatt aaaaatcaaa ccgatcctga cattttctga
    29581 agggaaaatt gttttattcg aaaaaatccg ttcaagtaaa aaagcatttg ctcgagctga
    29641 agaaattatt ggtagaagaa ataacgaaat acaaccgcca gtcaaacttt acgtgataca
    29701 tgcaaataat ttagaagtag cgattgcgga gaaagagaaa ttgcagaaaa aatatccaaa
    29761 tgcagaaatc gaaattggtc atttcggacc agtcattggt acacatttag gtgaaaaagc
    29821 catcggcatt gccatttcag cgcaataatt ccttttattc aaaaaacata ccaaaaata
//
LOCUS       DAXLPC010000027        28413 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.027, whole genome shotgun sequence.
ACCESSION   DAXLPC010000027 DAXLPC010000000
VERSION     DAXLPC010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.027"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            8..81
                     /locus_tag="ACF3UE_001169"
     tRNA            8..81
                     /locus_tag="ACF3UE_001169"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            101..173
                     /locus_tag="ACF3UE_001170"
     tRNA            101..173
                     /locus_tag="ACF3UE_001170"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:134..136,aa:Ala,seq:tgc)
     gene            201..274
                     /locus_tag="ACF3UE_001171"
     tRNA            201..274
                     /locus_tag="ACF3UE_001171"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:235..237,aa:Met,seq:cat)
     gene            288..361
                     /locus_tag="ACF3UE_001172"
     tRNA            288..361
                     /locus_tag="ACF3UE_001172"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Ile,seq:cat)
     gene            385..474
                     /locus_tag="ACF3UE_001173"
     tRNA            385..474
                     /locus_tag="ACF3UE_001173"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Ser,seq:tga)
     gene            487..560
                     /locus_tag="ACF3UE_001174"
     tRNA            487..560
                     /locus_tag="ACF3UE_001174"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Met,seq:cat)
     gene            579..654
                     /locus_tag="ACF3UE_001175"
     tRNA            579..654
                     /locus_tag="ACF3UE_001175"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Asp,seq:gtc)
     gene            656..726
                     /locus_tag="ACF3UE_001176"
     tRNA            656..726
                     /locus_tag="ACF3UE_001176"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:688..690,aa:Gly,seq:tcc)
     gene            740..813
                     /locus_tag="ACF3UE_001177"
     tRNA            740..813
                     /locus_tag="ACF3UE_001177"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Ile,seq:gat)
     gene            838..925
                     /locus_tag="ACF3UE_001178"
     tRNA            838..925
                     /locus_tag="ACF3UE_001178"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ser,seq:gct)
     gene            947..1018
                     /locus_tag="ACF3UE_001179"
     tRNA            947..1018
                     /locus_tag="ACF3UE_001179"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:980..982,aa:Glu,seq:ttc)
     gene            1041..1130
                     /locus_tag="ACF3UE_001180"
     tRNA            1041..1130
                     /locus_tag="ACF3UE_001180"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1077..1079,aa:Ser,seq:tga)
     gene            1143..1216
                     /locus_tag="ACF3UE_001181"
     tRNA            1143..1216
                     /locus_tag="ACF3UE_001181"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1177..1179,aa:Met,seq:cat)
     gene            1235..1307
                     /locus_tag="ACF3UE_001182"
     tRNA            1235..1307
                     /locus_tag="ACF3UE_001182"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Asp,seq:gtc)
     gene            1311..1383
                     /locus_tag="ACF3UE_001183"
     tRNA            1311..1383
                     /locus_tag="ACF3UE_001183"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1344..1346,aa:Phe,seq:gaa)
     gene            1388..1458
                     /locus_tag="ACF3UE_001184"
     tRNA            1388..1458
                     /locus_tag="ACF3UE_001184"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1420..1422,aa:Gly,seq:tcc)
     gene            1471..1544
                     /locus_tag="ACF3UE_001185"
     tRNA            1471..1544
                     /locus_tag="ACF3UE_001185"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Ile,seq:gat)
     gene            1556..1627
                     /locus_tag="ACF3UE_001186"
     tRNA            1556..1627
                     /locus_tag="ACF3UE_001186"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Glu,seq:ttc)
     regulatory      1816..1895
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1893..3086
                     /gene="metK"
                     /locus_tag="ACF3UE_001187"
     CDS             1893..3086
                     /gene="metK"
                     /locus_tag="ACF3UE_001187"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFD3634616.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3216..4688
                     /locus_tag="ACF3UE_001188"
     CDS             3216..4688
                     /locus_tag="ACF3UE_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFD3634617.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4771..5559
                     /locus_tag="ACF3UE_001189"
     CDS             4771..5559
                     /locus_tag="ACF3UE_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3634618.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5626..6294)
                     /locus_tag="ACF3UE_001190"
     CDS             complement(5626..6294)
                     /locus_tag="ACF3UE_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFD3634619.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            6409..8121
                     /locus_tag="ACF3UE_001191"
     CDS             6409..8121
                     /locus_tag="ACF3UE_001191"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634620.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8124..9893
                     /locus_tag="ACF3UE_001192"
     CDS             8124..9893
                     /locus_tag="ACF3UE_001192"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634621.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(10098..10664)
                     /locus_tag="ACF3UE_001193"
     CDS             complement(10098..10664)
                     /locus_tag="ACF3UE_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3634622.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(10664..11620)
                     /locus_tag="ACF3UE_001194"
     CDS             complement(10664..11620)
                     /locus_tag="ACF3UE_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFD3634623.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(11620..12276)
                     /locus_tag="ACF3UE_001195"
     CDS             complement(11620..12276)
                     /locus_tag="ACF3UE_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFD3634624.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            12646..14664
                     /locus_tag="ACF3UE_001196"
     CDS             12646..14664
                     /locus_tag="ACF3UE_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3634625.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    14734..14940
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15091..17505
                     /gene="leuS"
                     /locus_tag="ACF3UE_001197"
     CDS             15091..17505
                     /gene="leuS"
                     /locus_tag="ACF3UE_001197"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFD3634626.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            17853..19406
                     /locus_tag="ACF3UE_001198"
     CDS             17853..19406
                     /locus_tag="ACF3UE_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFD3634627.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(19787..21571)
                     /locus_tag="ACF3UE_001199"
     CDS             complement(19787..21571)
                     /locus_tag="ACF3UE_001199"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634628.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNFAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(21586..23307)
                     /locus_tag="ACF3UE_001200"
     CDS             complement(21586..23307)
                     /locus_tag="ACF3UE_001200"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634629.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLQIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            23407..24168
                     /locus_tag="ACF3UE_001201"
     CDS             23407..24168
                     /locus_tag="ACF3UE_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3634630.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IRERKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            25135..25403
                     /locus_tag="ACF3UE_001202"
                     /pseudo
     CDS             25135..25403
                     /locus_tag="ACF3UE_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            26075..>28413
                     /locus_tag="ACF3UE_001203"
     CDS             26075..>28413
                     /locus_tag="ACF3UE_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFD3634631.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTSNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATP"
BASE COUNT         8965 a         5078 c         6016 g         8354 t
ORIGIN      
        1 aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa ggggtcgcag
       61 gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag ctcagctggg
      121 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccatttcatt
      181 taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc ggttcatacc
      241 cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga cctttagctc
      301 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtcc
      361 attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag ggaacggtct
      421 tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc tcctttttca
      481 tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga aggtcgtagg
      541 ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg taggggttaa
      601 catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc gccatgcggg
      661 tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg attctcgtca
      721 cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg cctgataagc
      781 gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat tggttttggg
      841 gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg aaaccggcgc
      901 gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc cgttggtcaa
      961 gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt acgggtcatt
     1021 aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
     1081 aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct ttttcatatt
     1141 atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt cgtaggttca
     1201 aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg ggttaacatg
     1261 cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt ggctcggtag
     1321 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt ctgtcccgcg
     1381 ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt gtcgcgagtt
     1441 cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt tagagcgcac
     1501 gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt ttattggccc
     1561 gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc gaatcccgta
     1621 cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga atgattttaa
     1681 aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga cagttctaat
     1741 gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag aaaactgttt
     1801 tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg gagatgcctt
     1861 gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta tttacatcag
     1921 aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat gcaatcttgg
     1981 atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct gtaacaactg
     2041 gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt caaaaagtcg
     2101 tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt gatggagata
     2161 cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa ggagttgatg
     2221 aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt ggtgctggtg
     2281 accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg cctttaccaa
     2341 tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca aatgaattaa
     2401 cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat caaggacaac
     2461 cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta gataatgaaa
     2521 caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct gaattattag
     2581 atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt ggtcctcaag
     2641 gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt tatgctcgtc
     2701 atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct gccagctatg
     2761 ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa gcagaagtac
     2821 agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat actttcggta
     2881 ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc gatcttcggc
     2941 cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa acagctgctt
     3001 acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac aaagtagatg
     3061 cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc caagtggtgg
     3121 ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt atttatctat
     3181 ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca aatgttactt
     3241 tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt acaatcgtaa
     3301 caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg aactgggtat
     3361 tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa cttgcggata
     3421 aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc ggttcgttat
     3481 tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt caagggatgg
     3541 gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat tctattgaaa
     3601 agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt gtttttggac
     3661 cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt tttatcaatg
     3721 tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa ccaaaaatca
     3781 tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc atgcttgtct
     3841 cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt gtttctgctt
     3901 tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa agagctaaag
     3961 atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc aacttggctg
     4021 cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg tggatgcaag
     4081 gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta tcactagtct
     4141 ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact cattgggtct
     4201 tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt atgcctttca
     4261 gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc ttaggtgtga
     4321 ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag cttggtgtag
     4381 caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt tctatttttg
     4441 gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta acaaatgatg
     4501 cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat gcggatattt
     4561 tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta gttggcttgt
     4621 tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt ggtaaaataa
     4681 aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa agttattcaa
     4741 aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa tatttattcg
     4801 aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac aaaaaaggtg
     4861 attggcacca gttcagagca agagacaacg gatatacctg ttttatattt acttcatgga
     4921 atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta tgtagcaaac
     4981 tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga tacagtttat
     5041 gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca tgaattattc
     5101 ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat gggcggatat
     5161 ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat ctctctttca
     5221 ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa agcatctttt
     5281 tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga tccgcaatac
     5341 ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat ggcttgtggg
     5401 gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca ggaacaaggc
     5461 ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg ggaccaatgg
     5521 attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct taaaaagata
     5581 gctcctatag agatcacaaa catagtgatc tctataggag cttttttact gctcgttttc
     5641 tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg ttagaaagag
     5701 tgctttttca ttcaattctg catgggactg catactttct ttaaatccct ctaattgatt
     5761 ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat ttccgtccat
     5821 aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa tcaataaatt
     5881 gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac gaacaagtaa
     5941 ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag tattgatttc
     6001 taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca tatactgcag
     6061 caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt ccattgtttc
     6121 agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag caggtgcttg
     6181 aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt gtgtttcagc
     6241 caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt ccattttatc
     6301 aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt ctaattttac
     6361 agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat gaaattaatc
     6421 ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc cgtagcagtc
     6481 atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga agctattatt
     6541 acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct ggctttgcta
     6601 ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca aggcgtaagt
     6661 gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg aaatatcgaa
     6721 cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca aatccaaaat
     6781 ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat tggtgccttc
     6841 attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct tatcgttacg
     6901 gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat gatcattcaa
     6961 aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat tcgtgtagtg
     7021 aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag tgaggactta
     7081 acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc cttcatgctg
     7141 gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt taaagatgat
     7201 cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat tatgatggca
     7261 atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc gctgaagcgg
     7321 attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc agaacaagag
     7381 ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga ggatacagat
     7441 acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat cgtcggggcg
     7501 actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga tccgacagaa
     7561 ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag tttaagacaa
     7621 acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc tcaaaacttg
     7681 cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc tattgctcaa
     7741 gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga agaacgtagc
     7801 agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt tatcggtaat
     7861 ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc tgaaaagctg
     7921 gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat cgcacaaaaa
     7981 attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag attagtcggc
     8041 gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat ctttgaaact
     8101 caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa tttttctatc
     8161 actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg atcattgcta
     8221 cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa ttagctaatt
     8281 acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct gtaatatgga
     8341 aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt attttgttca
     8401 cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac aaattggaaa
     8461 aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt cgttttacca
     8521 gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc atcacgaatg
     8581 ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag ttagcttggg
     8641 ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc cgcaaagcac
     8701 ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat atggatgaaa
     8761 aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg attgaaggat
     8821 tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct tattctggtc
     8881 tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt atctttttcg
     8941 gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc ttagttgtga
     9001 cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca tctggataca
     9061 gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt gatgaaaaag
     9121 atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt cttgcgttgc
     9181 agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc tcgatcaatg
     9241 tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa acgacgatca
     9301 tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc gatggaatag
     9361 atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt ttgcaagaat
     9421 ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg gacgcttcag
     9481 atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc atgacgttag
     9541 aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca ggtcaaaagc
     9601 agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt ttggatgaag
     9661 caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg gatgaagcaa
     9721 tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg aatgcagata
     9781 gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac gagttattag
     9841 cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa taaagaggtt
     9901 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag cttctcatgt
     9961 ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt gaataaagag
    10021 gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac atatcattta
    10081 tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg cggctggttc
    10141 ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag tttggaacaa
    10201 aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta gacgacaagg
    10261 atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt gcgtgtagtc
    10321 tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt gaaaatccct
    10381 gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc ttgtagaaac
    10441 aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc atcgattgct
    10501 tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc tgctagaaaa
    10561 accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg ttgcaagatt
    10621 tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg ctcacctttt
    10681 tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca tcaattgcat
    10741 tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc cacggcgcat
    10801 cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg tcgcaaatga
    10861 cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag tcccgcaaca
    10921 ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata tctgaatcta
    10981 aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt aatccgttga
    11041 tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca tctaaataag
    11101 tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt gtttgcaatc
    11161 caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca actacttcat
    11221 ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt aaattgacta
    11281 cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta aaattttgga
    11341 aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg atttctttct
    11401 ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa ccagatacac
    11461 tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag tcaaatcctc
    11521 catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg taattccaag
    11581 aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct tctttctgta
    11641 agagttatct atttgttttc ttttttctct atacactgga taagtcaggc acagccaaga
    11701 aagactgagt aagtaaccgc cgatgatatc agtaggaaaa tgaacgccca gataaatgcg
    11761 gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg tgcgtaaggt
    11821 tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa tcatactgcc
    11881 tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg ccaatgaagg
    11941 acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa ttacaataaa
    12001 tccagaaacg aaccaaaatg tttctgccct ttttttctta taccacatcc ataaagccgc
    12061 acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa agagttggta
    12121 gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat cgaaaccaga
    12181 aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga caagaaagaa
    12241 gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt gaagcaatga
    12301 cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac caatgtatga
    12361 ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga aagacatttt
    12421 ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa tccttttaaa
    12481 caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt acggtaaatt
    12541 acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat attaagagaa
    12601 gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga aaacattgca
    12661 agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa acgaggggca
    12721 gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt acagccggtt
    12781 cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac agcggcattt
    12841 atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct atatgcatca
    12901 gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt atctcaagca
    12961 ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt ctacatggat
    13021 acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg acaatatcct
    13081 tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc atttggcaac
    13141 ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga tgcgacagct
    13201 tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa taatatcatc
    13261 gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg cggtggagcg
    13321 actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag caattctggt
    13381 aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg tgattctgtt
    13441 tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg gaacaacatc
    13501 caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca ggaaaatggc
    13561 tcttcgacga ataattccgg taacaatacc aattcttcag gaaatgctgg tacatcaaac
    13621 ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt ttggaagatc
    13681 tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat caagaacaat
    13741 ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa tgctggagca
    13801 aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc aagttcttct
    13861 aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg gagcgtctca
    13921 aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca aaataacttt
    13981 atctacccag gacaacaact gactgtttca aacagtggat caacaaacag cacgtcaggt
    14041 aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg cagcagttcg
    14101 tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc aaataaaaac
    14161 ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt catttatcca
    14221 ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg ttcaactact
    14281 tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc atccactggt
    14341 aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa caaacatcat
    14401 atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat ctatccagga
    14461 cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc agttactggt
    14521 tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga cagtcatgga
    14581 attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat ttatccaggt
    14641 caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt gaattccaca
    14701 aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg aagtagtaaa
    14761 aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc ttttgaactc
    14821 gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg gccgttacaa
    14881 cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta cgtcctataa
    14941 aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag aaaacaaagc
    15001 aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat aatagaaaca
    15061 agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga aattgagaaa
    15121 aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga tcctgaaaag
    15181 ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct acatgtaggg
    15241 catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag tcaaggatac
    15301 aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca atatgcgcta
    15361 gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt ccgacgccaa
    15421 atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac tgatccggag
    15481 tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct agcttatgaa
    15541 gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa tgaagaagtg
    15601 atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat gcgccaatgg
    15661 atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt agttgattgg
    15721 ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg agcaaatatt
    15781 gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg accagatact
    15841 ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag agaaattacg
    15901 acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa aaaatcagat
    15961 ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc ttatgcaatc
    16021 aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt atcttcatac
    16081 ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga attcgctcaa
    16141 actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa agctgcttac
    16201 acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa acaagaagca
    16261 atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga agtcagctat
    16321 cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat cccaatcatc
    16381 cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt acggttgcct
    16441 aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa tatcgaggag
    16501 tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac gaatacaatg
    16561 ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca taacaaaaaa
    16621 gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta cattggtgga
    16681 gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt cttatacgat
    16741 atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg aatgatctta
    16801 ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc tgatgatgtg
    16861 gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg gccattagat
    16921 gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt ggatcgtgta
    16981 tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac attgaatgat
    17041 ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga ctatgaaaat
    17101 cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc ctataaagtg
    17161 gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc gattgctcct
    17221 cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc ttacgcacca
    17281 tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt tttccaagta
    17341 aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga tgagctagaa
    17401 aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac agtcagaaaa
    17461 gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc tctttgtcaa
    17521 taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca ttctgtctca
    17581 gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga ttttcatgtt
    17641 ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct ctgtaatcat
    17701 caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga aattgagagt
    17761 acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga ttttgacgca
    17821 taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt attatcgaag
    17881 tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa agaataatgt
    17941 tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct gtatcgttcc
    18001 tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa ttaaataatt
    18061 tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt gtttttcttc
    18121 tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg cttagtcaaa
    18181 gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat ctttattttg
    18241 agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag ttattgctga
    18301 gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc ggaatgaaca
    18361 cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag tcttcgcctg
    18421 gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc attcttttag
    18481 ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat ataaatgctg
    18541 cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca aatgaagggt
    18601 tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat gatctcaaac
    18661 ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat tgggtatttg
    18721 tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg gggctgattc
    18781 ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca tggtttatct
    18841 attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa acatggcaaa
    18901 cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta ttttatggca
    18961 acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact ttgtacattt
    19021 acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg atcaatcagc
    19081 cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca cgtgaaagtt
    19141 tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg attccggaaa
    19201 actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact caaataagcg
    19261 cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat gcagggaaaa
    19321 tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc gttcagcaac
    19381 tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg ttcagcaccg
    19441 agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt gtaactcgtg
    19501 attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc gtattttaca
    19561 agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt aaaaagggat
    19621 tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc caaaaagtat
    19681 cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa aagctatcga
    19741 tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac gctatctgaa
    19801 attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca gaatgtgttc
    19861 ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt tcaatcgttg
    19921 acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc attgcttgct
    19981 gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa ataacgacag
    20041 gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct tgagataacg
    20101 tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga ataaagtgat
    20161 cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc attttcccgt
    20221 aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa accatcccaa
    20281 aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg aattcgatct
    20341 ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt tttcctgcac
    20401 cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg acttgattca
    20461 tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt tttcctttcg
    20521 gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca tctaatatct
    20581 caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca taagaagcgg
    20641 tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag aagccgatcg
    20701 tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg aaggcgagtt
    20761 gattaatgaa acgaatggcc ggatagatag caaagttcat aaattgagca cgtttaaaag
    20821 cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct tgctgattga
    20881 atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt aaaacaccca
    20941 gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta gttgtaacaa
    21001 ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg atataaaaca
    21061 gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg atacctgtca
    21121 ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg tcacctactt
    21181 gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt tcttttcgca
    21241 ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata aatgaagtga
    21301 tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat gcttgtttga
    21361 tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag agatcatcga
    21421 tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat aaactgcata
    21481 gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa cgtatcaaag
    21541 cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata ttccttgtga
    21601 ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag taccttgtcc
    21661 aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg tactgaggcg
    21721 ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg ctcttaatgc
    21781 tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga tctctgctgg
    21841 tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat aattagaacc
    21901 gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt cttctaattg
    21961 agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc ccatctgcaa
    22021 gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac tgatgtggga
    22081 gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta cttttcctat
    22141 cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag atccggtccc
    22201 gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt ctagaactgg
    22261 atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat ttgtctgatc
    22321 aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct ctgcttgcag
    22381 tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca ataccatagc
    22441 tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag tcacgacacc
    22501 gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag aagcataaac
    22561 gattcccatg agcaaaaaag caattggagt gacccaagca aatattcggt tcactttgat
    22621 catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat atgattgatt
    22681 atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga tggtgatccg
    22741 atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca gtcgataaac
    22801 aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata gagaataacg
    22861 aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca tttggcaaaa
    22921 taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca aaagagatcc
    22981 agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga aatatttctc
    23041 ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag aggcaactgc
    23101 agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt ttataactga
    23161 ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg gtacacctaa
    23221 tgtaccggcg atttgtaaac agatcatcac aaaggtaagg agagcgagtc ctttgttttt
    23281 ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat acttttcgat
    23341 tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa aaagaggtga
    23401 gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga tttgccaaaa
    23461 tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca agaagagaat
    23521 gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt tttttataga
    23581 aaattagata taccgatcaa acagatgaag aatttatatg gaaaaacatt gacggagtta
    23641 tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt gatgaaacaa
    23701 aaacaaaaag agataaggga gcgaaaaaaa cagttgaaat tgatgatcga tacaaacgag
    23761 gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga gtttgaagat
    23821 attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat gagtatgcca
    23881 gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt acatttattt
    23941 actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt cttattgaaa
    24001 tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag aatgtatgaa
    24061 aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac ggatgaaaac
    24121 aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga aatatgtgtt
    24181 taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct ggttcgatta
    24241 cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt tttagaggaa
    24301 atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg taattgtcct
    24361 cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat ggtgaactga
    24421 gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat gagaatgata
    24481 aattaaatag gtgcataaaa gcattacact taaaatacat tgttgcttac attattacaa
    24541 tatgttaata aggcaaaaat aaatagatgg attgaataaa catatttttt aatcaaatag
    24601 tccctactgt gactttcctc agctatcggt gatactaccg atagcatttt tttgcttata
    24661 aaataattat aagtatttag agatttttct tctaacattc ttcaaacaag aaaaatcaca
    24721 aaggttattg ttatttttat atattctttt taagaatgat tattttttta tagaaatttt
    24781 aaaaaataaa acacgttatt gatggatagt tagtttgtta tttggtaata ttatagaagt
    24841 tgactggtag tgatttattt ttcgttgttt tataaaaatg ttattttttg gaaaaattca
    24901 caaatatgta acgaatgttt ttctggaatt tgctgtgtta aaaagcagta tgactaatat
    24961 aaatactatt gtcatttatg caatttttta tggatagtaa ttttagaggg gaatcaatga
    25021 aggaagaata gaagggaaaa atagttgcaa atacgccagt tagcaaaaat agcaatacat
    25081 cttcaagctt taaaattcga gagaatcatc ttggtagtgg aatcaactac aacaaaagga
    25141 ttaaaccaat taatagatag aattaccaat ggaaaaatag aaaaggtagt tattctatac
    25201 aaaagttgtt taattcgctt cggttatgaa cttagtgaaa ccctttgcaa tatatggtac
    25261 agaatataga aattattgac attacagaaa atgatgaaga tttaatacag attgtcacta
    25321 tttgtagata ccttttacaa ggaaaccgag ccaataaagc taagaagatg attaaggagt
    25381 tgatggaaga cgatacaagt taagaaagta aaactacgcc caaataaaga gcaaaaagag
    25441 taattggacg tggaaaatgc aagaaatgaa ccatcgattc ggtggacagt ttattagtaa
    25501 tgacggtttg agaacatcca tgacgagaat gaaggaacat cctaaatgcg tttagttgaa
    25561 ccaagtgcca aataatatgg ccaaataagc gatcagttat cgatgaatcc caagtattct
    25621 aaactatata ttcattttga tgctaagcat tgatatattt ttttgggatt gatgaaggtt
    25681 aaccaataca gggactcact gatgaaattc tagagtctga ccttggtatc aacgatttag
    25741 tgattgtttc taatggaaaa gtataaaagt atataagtac attaacaaaa taactattag
    25801 ggttacgctc cagcttgtgc aaggcactgg caggaggaat cgtgaaatca taattatggt
    25861 taagccacac ggacaactaa aagtcataca aagctatcga atcaatcaac agaagacaat
    25921 cggcaatcat tagctttgtt tacagcttac attgcaacgc ttgagttgaa ccgaaaatac
    25981 gagggaggta acgcagccat tttgagttgg ggaatctttt tagaaaatta tcgggtacct
    26041 tgttgtttag tcaaaattat aagggggagt aatagtgagg aacaaatttc ataaactgtt
    26101 aagtatgttt ctagttatgc ttattgtgat caatcaattt gggaacataa cggttctagc
    26161 tgagtcttta gcagaacagc cagagcgttc gctgacgatc gaagttgatc aagaggaggc
    26221 tgctttgggt gagcagttcc agttgcgagt cagaggaaca ccagacctgc taaatgcatt
    26281 ggtcattgat aagagtgagg atttgattga aggggaagtg aagcaactca atgattacga
    26341 acgtctgatt acttattctt cccagcattc aggtaaatac gaattgaccg caagaagcgg
    26401 tgatattcaa tcaaatacgg tctcaataga aatcagtgta ccagaagaaa gcacaagtga
    26461 gtcttttaat gtaccagaag aaagcacaag tgaatctttt aatataccag aagaaagctt
    26521 aagtgaatct tttaatgaag ccagatcatc tgagccatct ataacgcagg aatctcagat
    26581 tgaaagacaa gaggagctct tgaattatga catcggcatc tctgctgagc gccccacttt
    26641 gccgagcagg catacacaaa cgttaaaggg atacattcaa ggaggcgctg gcgatattct
    26701 tgaagaatat ggggagatgg tcgtacgagt tcctagagca tcgattggct taattgagtt
    26761 cattagagtg gaggtcgctg atgattcacc tttaaagcca ctggcatttt accaagaagg
    26821 cacagacgtt gtttttccat ttacctttga ttatgaagga ttaaatgaag ccgctcagtc
    26881 gtatacattc agtatcacgt ttgaagttgc tttctttcaa tcaggcggta ctgagccaaa
    26941 taatgacttt caagtgagtc ttacttatgc tgagcgagca gcaaacacgg aattttcaat
    27001 tacgcctatt ccttcatcaa gacccatttt ttcgaaatta tactatggct ctagagaaat
    27061 cgacagccaa ggaaatcttg ggaatctgct gattgacggg caagacgtga ccaacagtaa
    27121 taaatttatt ttgcaggtaa attatgaagg atcacgaaaa gacggtgtag tggttaccga
    27181 tgtactaccg caaggaacaa ctttggcacc gaatccgact acatggagtt ccactggaaa
    27241 tagagaacct atttcaggtg gggttcggat cgcagaagta acgaatccag gtgaagcaaa
    27301 cgttagaact cattatgttt ccgaggaatt tgtggacaaa gtatctttta ataaggaaac
    27361 gaatacactt gttgtggact ttggtaatct agcagagggt caatcgtatt ttattgaata
    27421 tgctcttgaa gtgaccgatg tcgacttgtt caatgaagga agacaagagg atgggttttc
    27481 tcggaatcga gcgagtatga cctacaataa tcaggtaatg agccgagact accgcttgag
    27541 aatccctgaa agtaatcttc cggcaatctc tttaagaaaa agtgtggaca aaaatgttat
    27601 caatctcaat gaaaatgaac taacgtatac tctgcatgtc tcgatgtttt ctggaacaag
    27661 caatacgctt gttattgaag atgttttgga agaaggcatg gaatttgtgt catttctatc
    27721 agatattccc tctttcattg atgccgaagt caataatgga atagttcgtt tcagtgcgaa
    27781 taatacgatt ggtggtccga caagttttac cctctctttt aaggtcaatg tagaggcgta
    27841 tgcggtcggc gatcaaattt taaactttgc aacgcttgtg aatagtgaca atcgattgaa
    27901 tacgagtact gtaagaacaa ggaaaatcga tgggcgtatt aaagtaatta aaactgatga
    27961 gaatggccaa aggctggcag gagcaaaatt tgaaatttta tcaagcgatt cacaagtgat
    28021 acaagaaggt ataacggcag aaaacggaga atttttaagt gaaccgcttc ctgtaggtag
    28081 ctatcaagtc cgagaaacag aagcaccgga agggtatctt ttagatgcga cggtacatga
    28141 tgtttttata aatgaatact ccatagaaga agtgacgtta accattgaaa acatccttga
    28201 tacgggtggt gttgaactaa ttaaacatgc tgaaggcagt ggtgaagtcc ttcaaggagc
    28261 tgtttttgag ttacagaacc gagaaggaga aacgctacaa accggtttaa ctacaggaga
    28321 agatggaaaa ctggcaattg acggtttagc accaggagca tatcagctgg tagaaactca
    28381 agcgccaata gggtatgaat tagatgcgac acc
//
LOCUS       DAXLPC010000028        27990 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.028, whole genome shotgun sequence.
ACCESSION   DAXLPC010000028 DAXLPC010000000
VERSION     DAXLPC010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27990
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.028"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(20..967)
                     /locus_tag="ACF3UE_001204"
     CDS             complement(20..967)
                     /locus_tag="ACF3UE_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3634632.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(1096..1860)
                     /locus_tag="ACF3UE_001205"
     CDS             complement(1096..1860)
                     /locus_tag="ACF3UE_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFD3634633.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(1864..2253)
                     /locus_tag="ACF3UE_001206"
     CDS             complement(1864..2253)
                     /locus_tag="ACF3UE_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634634.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            2388..2930
                     /locus_tag="ACF3UE_001207"
     CDS             2388..2930
                     /locus_tag="ACF3UE_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFD3634635.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            3078..3710
                     /locus_tag="ACF3UE_001208"
     CDS             3078..3710
                     /locus_tag="ACF3UE_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634636.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(3844..3969)
                     /locus_tag="ACF3UE_001209"
     CDS             complement(3844..3969)
                     /locus_tag="ACF3UE_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFD3634637.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(4103..4996)
                     /locus_tag="ACF3UE_001210"
     CDS             complement(4103..4996)
                     /locus_tag="ACF3UE_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFD3634638.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(5178..6104)
                     /locus_tag="ACF3UE_001211"
     CDS             complement(5178..6104)
                     /locus_tag="ACF3UE_001211"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFD3634639.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(6189..6950)
                     /gene="pflA"
                     /locus_tag="ACF3UE_001212"
     CDS             complement(6189..6950)
                     /gene="pflA"
                     /locus_tag="ACF3UE_001212"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFD3634640.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(7194..9425)
                     /gene="pflB"
                     /locus_tag="ACF3UE_001213"
     CDS             complement(7194..9425)
                     /gene="pflB"
                     /locus_tag="ACF3UE_001213"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFD3634641.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(9702..12152)
                     /gene="parC"
                     /locus_tag="ACF3UE_001214"
     CDS             complement(9702..12152)
                     /gene="parC"
                     /locus_tag="ACF3UE_001214"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFD3634642.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(12164..14209)
                     /gene="parE"
                     /locus_tag="ACF3UE_001215"
     CDS             complement(12164..14209)
                     /gene="parE"
                     /locus_tag="ACF3UE_001215"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFD3634643.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(14375..14809)
                     /locus_tag="ACF3UE_001216"
     CDS             complement(14375..14809)
                     /locus_tag="ACF3UE_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFD3634644.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            14936..15574
                     /gene="plsY"
                     /locus_tag="ACF3UE_001217"
     CDS             14936..15574
                     /gene="plsY"
                     /locus_tag="ACF3UE_001217"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFD3634645.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(15706..16581)
                     /locus_tag="ACF3UE_001218"
     CDS             complement(15706..16581)
                     /locus_tag="ACF3UE_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFD3634646.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(16663..17454)
                     /gene="codY"
                     /locus_tag="ACF3UE_001219"
     CDS             complement(16663..17454)
                     /gene="codY"
                     /locus_tag="ACF3UE_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFD3634647.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(17472..18872)
                     /gene="hslU"
                     /locus_tag="ACF3UE_001220"
     CDS             complement(17472..18872)
                     /gene="hslU"
                     /locus_tag="ACF3UE_001220"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFD3634648.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(18886..19434)
                     /gene="hslV"
                     /locus_tag="ACF3UE_001221"
     CDS             complement(18886..19434)
                     /gene="hslV"
                     /locus_tag="ACF3UE_001221"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFD3634649.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(19471..20376)
                     /gene="xerC"
                     /locus_tag="ACF3UE_001222"
     CDS             complement(19471..20376)
                     /gene="xerC"
                     /locus_tag="ACF3UE_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFD3634650.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(20574..21950)
                     /gene="trmFO"
                     /locus_tag="ACF3UE_001223"
     CDS             complement(20574..21950)
                     /gene="trmFO"
                     /locus_tag="ACF3UE_001223"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFD3634651.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(21919..23997)
                     /gene="topA"
                     /locus_tag="ACF3UE_001224"
     CDS             complement(21919..23997)
                     /gene="topA"
                     /locus_tag="ACF3UE_001224"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFD3634652.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHGHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(24119..24976)
                     /gene="dprA"
                     /locus_tag="ACF3UE_001225"
     CDS             complement(24119..24976)
                     /gene="dprA"
                     /locus_tag="ACF3UE_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFD3634653.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(25032..25799)
                     /locus_tag="ACF3UE_001226"
     CDS             complement(25032..25799)
                     /locus_tag="ACF3UE_001226"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFD3634654.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(25792..26652)
                     /gene="ylqF"
                     /locus_tag="ACF3UE_001227"
     CDS             complement(25792..26652)
                     /gene="ylqF"
                     /locus_tag="ACF3UE_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFD3634655.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            complement(26746..27705)
                     /locus_tag="ACF3UE_001228"
     CDS             complement(26746..27705)
                     /locus_tag="ACF3UE_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3634656.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDESFIQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         7486 a         5957 c         4790 g         9757 t
ORIGIN      
        1 atatatatag taataagact taattcgttg tctctctgat aactagttca ggaaaaaaac
       61 gacgataacc ttgactcgcc cctttttctt ctattttttt taacaacatt tctccacata
      121 cttcacccat acgtataata tcttgcttga tcgttgtcaa tttaggtgaa ctgatttggt
      181 ctaaaaatac cccatcaaat ccaatcacac caaattcttc gggcaagtgt cctccagcat
      241 ttataatccc tcttactgct cctagtgcta gccgatctga actacataca aaacaagttt
      301 tatctgtaaa atctgcccag ttttctgtca tatatctttc tacttctgtc gaatgatttg
      361 gaaaccgcaa gattttacta ggaagatcaa cttccttcat cacagataaa taaccagttt
      421 cccttgaaat ttcaaaaggc tcgtccactt cgataccgat ataaataatc gtttgataat
      481 ctctttctaa ggcatattgc gttgcttttg ctgtaccata ttcattatcg ctgtctacat
      541 aatcatatcc ttcagaattt tccccaaaca agacaactgg tttttccaaa cggtcgatcc
      601 aatcgaagtc tttttttctg acacctgtga tgatgtatcc atcacaagaa ccgacgtcga
      661 aggcatcatt tgtaactaat tggagagaat aatgcgcttt accgatccgt ttagcgattc
      721 ccatcagcaa attcatgtaa tagggctcag ttgtgtcgat ttcttccagt ataaataatt
      781 tgatgatctg cgaccgattc gtgacaagtg cttttgcagc aatatttgga cggtaatcca
      841 gttcagccat tgctgagaaa actaactctt tcaattcgtc agtcacctgt tccggatgat
      901 tgatgactcg agagaccgtc atttttgaaa cattggcacg ttttgcaaca tctgctaaag
      961 tgggcatgct ctcttccttt ctaacatgtt gtcattctta ctatcaatta taccaaattt
     1021 tcctaacaga gtttattata gcccaaaata aaaaacggaa aatcctctat cgtcatgagt
     1081 gattttccgt ttcaattatt tatacttttt tatcaaattt tttgctaaaa aagtggaagc
     1141 ttcttccatt agtggtattt gtaccatatg tcgctgtgtt tttgaggaac gaaaaacaat
     1201 ttcttttccg taagacttat gccgattttt ttctacaaat cgttccgttt gtatataagg
     1261 gattttttcg tcagcttgtc catgccaaaa gaacagagga cgtccagcta acttttccgg
     1321 ctgcaatgac aaatcatagc tcttaaccca tgaaatcaaa tcaaaatagt cttttggtac
     1381 gacataatta tattccgatg cgcgccttac gatttctttt ccatattcca aaggtgcagg
     1441 ggaacccatc aaacacacgc ccgctactat atgaggatgt ttagccaaca aggcgcatgt
     1501 tgtcattccc cccatcgaaa ccccgccaac tgcaagctga tcatgtagaa gacctctttt
     1561 ttctaaatgc ttgataagtg tgtcaaattc aaacagattt ccgtagatac tatcccaaaa
     1621 tgtataggat ggaatagaag aaaccggctg tttgcgctcc ccatgattca tcgcatctgg
     1681 caggatcaca cgaatgccct gctgcgcaat ttttcttcct tgcgtcaaaa ctaactcctt
     1741 acttgtctgc catccgtgat aatagatgac aacgggaata cgttcctctc ttaattcttt
     1801 cagaacaact tctaacactg gaatatgatg gacagaacgt ttcaatataa ttggattcaa
     1861 ttgttactca cctattttca ttaaatttcc tgatcgccat agcaaccatg ctccaacagt
     1921 tgtctggaac aggttcagtg taccaaataa tataaatgca ggactgaatg gctcgggaaa
     1981 taagcacaga gaacaaagtc ccaccactcc taatgctagc gaaaggagtg gataaataga
     2041 aaaattcaaa aaactggcaa cgctaccgaa aatattacca ataaacagta tcaaaaagaa
     2101 aaaaacgctt aaaattaaac catctgtcag cgacatctga aaaacaatgt tctctacctc
     2161 aattggctgt tgaatcgaat agacacctaa gtatatactg agaaggagac ttagcacgtg
     2221 gctggcacaa aacacacgat tgaccgtttt cattttaatc acctaaccta tctttataat
     2281 tctattataa tcattttatc atttttttgt atgtataaag tttcaatttt tcttcactta
     2341 cgattttttt tgatattgtt gttatataaa tgaaaggagt tttacaaatg attgatccaa
     2401 aaatgttggg gatgatcttc ctcattaatt ttgcttatat cactctgaac acgttacgtt
     2461 tcatgttgac aatgaaaggc tatcgactga ttgctccact tgtcagtatg gtcgagatca
     2521 cgatttatat cgtcggctta tcccttgttt tagatcgttt agataatcca ctgaatttat
     2581 ttgtctatgc gttaggttac gcagtaggta tcagtgtcgg aattttgatt gaagacaaat
     2641 tggcattagg atacatcatg gtcacaacga ttttgccagc aaatagcgca gaagataaaa
     2701 gtttgccggg tatactgaga gaacacggtt atggtgtgac acagacttct gcaatggggc
     2761 tggaaggtga gcggctagtt ctcgaaatac tttctcctag aaaaagcgaa cgtgaactgt
     2821 atcgcctgat caaagaaatc gaagagcgtg cttttatcat ttcttatgag ccaaaatata
     2881 tttcaggtgg tttctggact aaaaaagtga gaaaacgaca aggaaaataa ctcacaaact
     2941 taaaaactgt ctaatatcta aattaaattt taaatgttag acagttttta tttattattt
     3001 tgattaaaaa acatcgacat atactcatca atttgttatt atactttata tacttatcaa
     3061 tttaatttgg agatattatg gaaattcaac gtagaaccac taatttttta catttaggct
     3121 ctttttttgc aactttgacg atcttatttt ttctatgtta ttcatacctt aagacctcac
     3181 atgcgccttc tagtgcatta ggctggttgc ttttggatca ttctgatatc acagaagccg
     3241 aagaaaatcc gttttttttg attttgtctt ctctttgcgg cttactgttt tctgtttatt
     3301 tcggtgccta tttttttcat cgacatcctg gtacgttaaa cgaagcttca agcgtattga
     3361 ttgcatttaa aacgttttct tttttagcaa ttctttttta ttcgtttaat cacaatacgc
     3421 ttttcttctt tatcatgaat ggtttagtcg tgattttatc catttttact tattttattt
     3481 tttcactcat ttttagccaa ttgaaatgtc cgctcttctt tcgattagtt cctgtcacct
     3541 gttttattta cagcttgttt tccttttttg tccttgcttt aatgccactg accaaccctt
     3601 cgacgatcca agtcgcagga aatctgttgg atatgctctt catcgtcagt ctaggtgtat
     3661 ttatgtggca aagaaaaaac aaacaaaata aaaagcattt tgaagcctga ctattacgac
     3721 ttcataaatg cttttttagt tttaaacact tcaatctaaa agaataaccc aagattggat
     3781 aaattattaa tgactcgcca ttcgtttctt agtgattctg gattatcaaa tggacttcct
     3841 aatctaatca gctagttctt cccataaaat gccatacttg actgaatcat aatattgatt
     3901 atttaaaaat ctaacttttc ttatcactac ttcctttgtc attccacatt tctcaccatt
     3961 tttttgcatt cctttgtttc cagaccatgt agtgaatcta ataggtggta gataggcaaa
     4021 atactcaaat aattctttta accataaagg aagagaaagg ctcctcctgc aagagtcagt
     4081 ataatttttg cttactgctc tcttaggttt tactcactaa aactgttcca tattctttga
     4141 tataagaaaa tgcatgcggt ataaatttct tgctcagctc agaaaagatt tgtcgtttaa
     4201 gaaaggccat ttcctccatt gtcaatgaag gatccaatgt tggtaattca atctcaaaat
     4261 tgtttttttc gacaataggt aattctaatg tgaatgattc ttcttccttt atagtattcg
     4321 tcacaagtag agactgatgg aaaatactag gccggcgatt tttatattta ttcttacgta
     4381 tcctgtcaac gataacttct atttgatcaa aaaagtacga ttcatttacg tctccaataa
     4441 gttcggctaa ttctttgaat gccttcgtta caggaagctg attcttctgt acaaaaaagt
     4501 aattagccaa agtaagcggg aagtgttcta tagaggaaag tgtgataaaa cggtacttct
     4561 catttcctgc agttgtcctc agcaattctg tctctcggct gtttcttact ccataaaaat
     4621 acgcttcttt ccgttcatct tcgaaacaat acgcccaaat aacttctccc atcgctaatt
     4681 tttgttcatc aacagagagt ctcttcaatt gttcagctat ggtttcagca gccgaagtgg
     4741 cttgttgcaa gtaatcttta ggatcaaata ttggaaagtt caaatgatat cttcgttctt
     4801 ccctcttgat taatcctgca tcgatcaata aatcaagaaa atgggaaaat ttattttgcg
     4861 aaaattcttt tttcaattct cttagaatcg tttcttgttc tcgatgttca tatagataat
     4921 cggtcaatga agaaaaaagc ggatcatcgg tcagtttttg ataaaagttt tccttatttt
     4981 ttgaataata gttcatatat gttctctttt ctatccgttt tattttactt aaaaggcttt
     5041 tacgtaaaaa ggaggaagaa caagagtcat aattgactgt tattctcctc catttcttcg
     5101 gcctttagta tgttctatgt ttctttttat atcaatcgct tatccattca ttttgaatgc
     5161 ttcatactac catttgatta gctaaataca gccgtcaatt gaggtacgac ttgtttttta
     5221 cgtgaaacga cacctttaag caaagcacgg ttgttggtca aagttgtttg gaaagcttct
     5281 tctacttttt cttttccttt accagcaaca agtaattctg aatcactgtc taagatgttt
     5341 gtgacaacta atacgaacag atcgtagcca tttgctttca tttcatcttc cattgctgct
     5401 tctagctctg cttgtcgatc catcacttca ttaaggtcca ctgtattgac ttgagcgata
     5461 cgaacgttgg aactgcccat tgggaaactt tttgcatcca aatcaagaag aaccgcagct
     5521 gatttatcac ttagatttgt tcctgctttc aacatttcaa gtccataagt gtttagatcg
     5581 acttcagcga ttgctgcaag ttcttttgca gctgcttcat cttcaggcgt acatgttggt
     5641 gatttgaaca acaatgtatc tgaaatgata gctgagagca tgattcctgc gatttcttta
     5701 ggaattgtta cttggttttc tttatatagt tttaaaataa tcgtacttgt acatccaact
     5761 ggttctgcac gatagtacaa tggattagct gtttcaaagt ttgcaatacg atggtggtct
     5821 actacagcta aaatatttac ttcgctgata tctgaaatac tttgttggaa ttcattatga
     5881 tccacaagca tgacatctgc attttctgct ttagctgact ctactactcg tggtgcagat
     5941 agctgaaagt ggtctaatgc gtattgtgtt tcttcattag gtgtacctag agcaactgct
     6001 tctgtttctt tacctaattc attttgcaag tgtgaaaacg caatggctgc cccgattgca
     6061 tctgtatctg gattttggtg accaaaaact aaaatttttg acatgtcatt cgctcctttg
     6121 tgatttctcc tatttaataa tagcaaaaaa acggaaagaa gcaatactta tcttctttcc
     6181 gatgcgacct atcgcgttaa atattttgta tactcttctg tatgaagcaa tcgtttagca
     6241 ttttcgacac gttcttttgt aggtggttcg atcccttcta atggatattt caaaccaagt
     6301 gtttcccact tgtattttcc catcgtatga taaggaagaa tctctactct gtctacattt
     6361 gacaaggttt gaataaagtt gtctagtcgg atcaaatatt catcataatc acttcgctca
     6421 ggaactagta catggcgaat ccaaaccggt ttgttgattt ttgacaaata ttgagccatt
     6481 tctaaaatat tttcattgtc ccaatgcgtt agttttttat gctcttcatt atcgatgtgt
     6541 ttgatgtcaa ataacagtaa atctgtatac ttcatcaatt cttgaaaacg tgaaaagaaa
     6601 ggttcttcat acgtaaaagg ttttccgcat gtatccaatg tagtatgcat cttccgctct
     6661 tttgcttttt taaatagttc gatcaaaaaa tcgatctgca atagaggttc tccaccacta
     6721 acagtaatac cacctttatc tccccagtaa ggtctgaagc gttctgcttt atctaaaagt
     6781 tcatctgctg tgtattcttt ccctccgcca atattccaag tatctggatt gtgacaaaat
     6841 tggcaacgca tgcggcatcc ttgcataaac acgacaaagc gcagtccagg tccgtctact
     6901 gaaccgaaag tttcgataga atgaacatag ccgattgttt tttcttccat ttaagttcac
     6961 atcttttctt tgatttcatt ttaagtacaa gttagctgtc gaagcgaagc tttctgaaca
     7021 aaatttttcg caattgccgc ttcgttatgt gtaaaattta cagggacgga acatacaagt
     7081 cctgcccctg taaatcgttt ctttcaaata agcatactga ttattcgatt ttgatgcgat
     7141 ggctattcaa cgtcctttcg acgctaagtc gaaaaacttt tttcacgaac tttttacatt
     7201 ctgtcgtgtg aagttctcat caagacatct aattgttgtt ctcttgtcaa gtcacggaat
     7261 ttaactgcat aaccagatac ccggatcgtc aagttcggat atttcattgg attttccatt
     7321 gcatcacgca ataaatcatt actgaataca ttgacattca aatgataagc tccttttgag
     7381 aagtatccat ctaagacatt acgcaagttt tcgattcttg tatcttgttc ttttccaaga
     7441 cctgaaggat tgattgtttg ggtatttgaa attccatcca atgcacagcc gtaattcatt
     7501 ttagctgttg agttcaggct agctaataac ccactttgtt ccgcattgta acttggattt
     7561 gctcctggcg caagtggttt tccagcttca cggccatcag gagtatttcc tgtattttta
     7621 ccgtaaacaa catttgaagt aatcgtcaat aatgaagttg ttggttttga gttgcggtaa
     7681 gttttatgac gtttgatttg tcccatgaag tattccaaga tccatgaaac taattcatct
     7741 gcacggtcat catcatttcc gtatttaggg aagtcgccat ccacttcaaa atcaactgct
     7801 attccttttt cattacggat tgcttttact tttgcatatt tgatcgctga caagctgtct
     7861 gccgcatgag agatcccagc aatacctgta gcaaatgtgc gttgcaagtc agaatccatc
     7921 aaagccagct gagctgcttc ataagaatat ttatcatgca tataatgaat gatgttcaac
     7981 gtattgacat atagttctgc taaccaatcc atcatattca tgaagttatg tttcacttct
     8041 tcaaagtcta gtatttctga tgtgattgga cgatattctg gtccaacttg ggcgccagtc
     8101 acttcatcga ctccgccatt gatggcatat aatagtgttt tagccaagtt agcacgagcg
     8161 ccaaagaatt gcatgtcttt tccgacaact gttcctgata cacagcaagc aatcgcacaa
     8221 tcatcagaac cccattgttc acgaagctga ttatcatttt cgaattgaat cgaagaactt
     8281 tcgatagcga ttctgctagc atatgttctg aatccttctg gaaggtgttc agaatacaaa
     8341 acagtcaagt ttggttctgg tgaaggtccc atatttgtta atgtatgaag cagacggaaa
     8401 tcattctttg taactaatga acgaccatct aatcccatac ctgcaatgga taaagtagcc
     8461 cagataggga atcctgagaa taattggtta tattcaggtg tacgcgcgaa tttgaccata
     8521 cgtaatttca ttactaagtg gtcgatcaat tcttgtgctt ctttttctgt gattactcca
     8581 ttatccaaat cacgttggat atagatatca aggaatgctg agatacgtcc gattgacatc
     8641 gcagcaccat tttgtgattt gattgctgct aaatatccga agtatagcca ttggacagct
     8701 tcttttgcat ttgcagctgg tttagaaata tcatagccat atttcgcagc catttctttc
     8761 atttgcgcta atgcacgata ttgttcagtg atttcttcac gtaaacgaat cacttcttca
     8821 ctcattgtat gataaccagt catatcatga tcttttttct tttgttccat caaatagtcg
     8881 attccataca atgccacacg acgatagtca ccgatgatac gtccgcgacc gtaagcgtct
     8941 ggaagccctg taatgatttt gtttttacga gcagcacgca tttcagcagt ataagcgtca
     9001 aatacacctt gattatgtgt tttgcgccag tcagtgaaaa tatgtgtcaa ttcatcgttt
     9061 ggtgtatagc cattgctttt tagcgcattg ttagccatat tgattccgcc gaacggcatg
     9121 aatgcttgtt tcaaaggttt gtctgtctgt agaccgacga ttttttccaa atctttatcc
     9181 aaatagcctg catcgtgtga agtaatagtt gatacgattt ctgtgtccat atcatagaca
     9241 ccgttacgct cgaattggat atcatttaac ttttgcaatt catcccataa tttttctgtt
     9301 gcttctgttg ggccttccaa aaagctgtca tcaccgcgat attcagtgta gttattttga
     9361 ataaagtctc tagtgtctac gccttctttc catttggtac ctttaaatcc attccattgc
     9421 tccattgtat ggacctccta aatttctgtt ttatgtaaca gtttttacgt gattagtata
     9481 acacagcacc ctatctttgc aagggttttc ttgtttttta tttaacaatt tttatgtttt
     9541 atttacatat atttaaatca acgttgacat accaacattt aagcattgtg aacactttca
     9601 tctttttttg caaacgtata aggatttatt aaaaatgaat gaaaaagaga cgccacctgt
     9661 attaatacag atggcgtctc ttcattaaaa tactacaaca gttacgactc gatgaaaatc
     9721 tcaggagcat cgataacttc gatgacttct ccaccttttt tctcatccat cgcaaatgat
     9781 ccattcgatg ttcgatcacc tatagggaaa tcagttgggt caatcgttaa ctgctgccct
     9841 ttttgattca tcaaggttat ttcttttgat cttccttccg acatatagat aatacggtgc
     9901 ggattttttt tcagctcacg catgaccgtc actccccgct tcgcacgtga agtttggctg
     9961 atttcttgag caagcatgcg tttaacagct cctcgctgag taacgattac gatcggcgta
    10021 tcaccttctg ctaacacaag cagcccgttg ataatcctat ctccatcttt caaattcata
    10081 gacttcactc cagctgcctt tgctccaaca acgggaacat ctgttaaagg atagcgcaaa
    10141 cccattcctt gatgcgttac taagaaaaca tctaagcctg gctgatcttc tttcagatac
    10201 acagcaatca gttcatcttc ttccgccttt agcttcatac agctgagcgg acggctctta
    10261 taggtgcgcc atggttcgaa ctctgtcatt cgtgtttgct tgatcaatcc attcttgctg
    10321 atgaatacaa atgttttctc tgcttgaatt ttttgatatg ggaaaacagc taaaatcgat
    10381 tcgtctacag acagattgga gattgtttga gaaatgtgct caccagcatc tttccatttc
    10441 aaatcgggta gttcatggac agggcggtag atcacatttg ctttatttgt gatcagaaga
    10501 acatggtcca atgtactcaa ttcacctgag tatagcaagt agtcgccttc tcgcatcccg
    10561 atttcttctg gtttggaagc actataagaa cgaaggcttg ttcgcttcac atagccttct
    10621 cgcgtcacac tgacaattac gtcttcttgt gccactaaga cttgcgtatc aattttgatt
    10681 tcttcgattt cgtcttcgat tgtcgttaga cgagcggaag aataattttt tttcacttct
    10741 cgcaattctt ttttcataac agagaaaagc tctttgtcat ttgaaaggat tttattcaac
    10801 tctgtgattt gcgcaatcaa gctttcggat tccttttgaa gctctgtgat atccgtgttc
    10861 gtcaaacggt ataattgcaa tgtgacaatt gcttctgctt gttcttctgt aaattgaaag
    10921 acgtcgacta aattcttttt ggcgtctttt ttgtctttac tttcacgaat cgttgcgatt
    10981 acttcatcca gaatcgataa agctttcatc aatccttcta cgatatgctg tcttttttga
    11041 gctttggcta aatcgaattg actacgtttt gttatgactt gctttcgatg ctcgatataa
    11101 cttcttaaaa tgtctttcag tccaacttga tgcggagtca tatggtcgat agcgaccata
    11161 ttgaaattgt aattgatctg tagctcagtg tttttgaaca aataattcaa aattccttga
    11221 gcattggcgt cttttttcaa ttcgacgaca atttgcagac ctgttctatc actttcatct
    11281 cgtacttcag ctattccatc gattttctta ttcaaacgga tctcatccat ttttttcacc
    11341 aaggtcgctt tatttacttc atatgggatt tctgtgatca cgatttgctg tttattaccc
    11401 ttcattgcct ctatctttgt tttcgaacga agaataactt ttcctcgtcc tgtttcataa
    11461 gcttttttga tttcatcttt tccttgcaag atccctcctg ttggaaagtc aggtccagga
    11521 atatattcca tcaatttttc aaggctcgct tgtggatgat cgatcatata gattgtgcca
    11581 tcgatcactt cagctaagtt atgagtcggg atttctgttg catatccagc agatatacct
    11641 gtcgatccat tgacgagaag gtttgggtat cgagctggaa ggactgttgg ttctttttct
    11701 gtatcatcaa aattccacac gagatcgact gtttctttct cgatatctgc tagcatctct
    11761 ccacttaact tggataatct ggcttcagta taacgcatcg cagcaggtgg atcaccgtcc
    11821 atactcccgt tattcccgtg catttcgatc agtacttccc gcaacttcca gtcttggctc
    11881 atgcggacca tcgcttcata aatactgatg tcaccatgag gatgataatt ccccatgata
    11941 tttccgacag attttgctga tttacggaat cctttgtcat acgtattgcc atctttgttc
    12001 atggcaaata atatccggcg ttgcactggc ttcaatccat cacggatatc aggcagtgca
    12061 cgttcttgga taatatattt ggaataacgt ccgaagcggt cacccatcac ttcttctaaa
    12121 gttaattctt gtacttcttg tcgattttcc atcaggtgac ctcctattct acttcaaata
    12181 actgattgtt ttcattttta tctgctcgtt cttcatctaa taaatcatta gaaactgaag
    12241 gagagatttc agtatcctct tttttatcta agatactgcc atcttcttcg agcgtaaatt
    12301 gcacgtgatt ttcgatccat tttcttcgag gttctacttt gtcacccatc agtgtggtta
    12361 ctcgacgttc agcttgcgca gcatcatcga tacggacgcg gatcaacgta cgggaagtcg
    12421 gatccatcgt tgtttcccac aattgttccg cattcatctc tccaagtcct ttatatcgct
    12481 gcagcatata tcctttgccg acttttttaa tcattgctgc caattcgtca tctgtccacg
    12541 catattcaat gacttgcttc tttccttgtc ctttggatac tttatataaa ggcggtaacg
    12601 cgatatatac tttcccagct tcaatcagcg gtttcatata acgataaaag aaagtaagca
    12661 gtaatacttg aatatgggcg ccgtctgtat ccgcatcggt catgatgatt actttgtcgt
    12721 aattacagtc ttcgatagaa aactcaggac cgactcctgc accaatcgta tagatcatcg
    12781 tattgatttc ttcatttttc aagatatctt gcattttagc tttttcggta ttgatgactt
    12841 ttcctcgtaa aggtagaatt gcttggaact ttctgtctct tccttgttta gcagatccgc
    12901 cagcagaatc cccttcgact aaatacaatt catttttctt agggtttcgg gattgtgcgg
    12961 gtgtcaattt tcctgaaaga agagattcgc cttttttacg cttcttccca tttcggcttt
    13021 cttctctggc tttacgtgct gcttctctcg cttctctggc tttgattgct ttacggacca
    13081 acatctggct catttcgcta ttttcctgca aataaaagcc catttgttca ctgatgacgt
    13141 tatctactac ggtacgagca actggcgtac caagtttttc ttttgtttgc ccttcaaatt
    13201 gcagaagatt ttcaggtaca cggatagaaa gtacagcagc taacccttct ctgaaatcac
    13261 taccttccag attcttgtcc cgttctttca gcaaaccaac ttttctcgca tattcattat
    13321 aagatttcgt catcgccgct ttcataccag cttcatgggt tcccccatct tttgtccgaa
    13381 cgttattgac aaaagataaa acattttctg aataaccgtc attgtattga taagcgacct
    13441 ctacttcgat accttctttt tctcctgaaa aataaacaac tggtgtcaat gtatcttttt
    13501 cttcattcag ataatcaaca aattctttga ttccttcttc gtaatgaaaa atttccttga
    13561 ctggttcttc tccacgaaga tcagaaagag agattttaac gccttttaga agaaaggcag
    13621 attctcttaa ccgttcggct aaaatttcat atgaaaattt cgttgtactg aatattgtat
    13681 catctggtaa aaaatggaca gtcgtcccgt ttgctttttt tgtttttcct atctttttca
    13741 aagtaccgtc aggtttaccg ccgtttttaa atttctgctg atactctacg ccatctctaa
    13801 cgatcgttac aattagccat ttcgataagg catttaccac actggctcct acaccgtgca
    13861 gtccaccaga agttttgtac cctccttgac caaactttcc gccagcatgc agcacagtaa
    13921 aaatcacttc aactgttggt attccggaag catgcattcc tacaggcatc ccacgtccgc
    13981 tatctgcaac agttatacta ttgtcttcat ggatggtcac atcaatctca ctgccataac
    14041 ctgataatgc ttcgtcaact gcattatcga cgatttcata gactaaatga tgcaagcctc
    14101 ggctgtcagt ggatccaatg tacatccctg gtctttttct aactgcctct aatccttcca
    14161 atacttggat ggacgagtca ttgtattcgt tgtttacttt ttttgccaag gcaaacgctc
    14221 cttcaataat actttgcggc aaaaccgcac cacgattatc atactagaaa aggtcgtgaa
    14281 aaaaaagagg gtagacgaga aatcaatttt aattatctcc taaccgcttt ttcgacattc
    14341 ccctctatcg atcatctctt ctttgtggtc atttttattt ttggttttct ttcaacttac
    14401 caagttcaat cttaatacaa cgatccatta cgatatctgt acgtcctgct tttcttagca
    14461 tctcagctgc ttctttgttt tcaatcccta attgtgccca gaacacttta gcatcagttt
    14521 tcaaaaaatc acctgctatt tcaggtaaaa attcactccg tctaaataca tctacgatat
    14581 cgattggatc atcgatttct gtcaaattcg catagacttt ctcgcctaga atttcttcac
    14641 cagccaataa tggatttact ggtatgattt tatatccatt gtcttgcaat acctgtgcaa
    14701 ccatgtaact tgttcgttct ggtttattgc tcaagcctac gacggcaata ttttttgctt
    14761 cttccaaata gttgaaaatc gtttcttgtg ttggattttt tacagacatt tctgccaccc
    14821 cttgcttttc tttttattcc atctattata cttgtatctt tcattttttc aattgttcct
    14881 gttacctatt catgctaaaa taaaggatag ttttcaactt gaaagagggt aaaaaatgaa
    14941 attgatctta ttacttattt tagcatatct tttaggttct attccttccg gtgtctggat
    15001 tggcaaattg tttttcaaaa aagatatccg acaacacggg agcggtaata ctggaacgac
    15061 caatacattt cgtgtattag gcaaaacagc cgggattgtt gtcctgctta tggatatttt
    15121 aaaaggtaca ttggctactt gtttgccgat gatcttccac ctttctggga ttaaccctct
    15181 ttggtttggg gtatgcgcca ttcttggcca tacatttccg atttttgctg ggttcaaagg
    15241 aggaaaagct gttgcgacaa gtgcaggaat gcttttagga tttaatcctg tattttttgt
    15301 ttattcttgt atcatcttta tcgttagttt attttgtaca agtatggtga gtttgagcag
    15361 tatgatcagt gcagtattga tcactttatc tacgatcgtc cttccttatg tagctcctgt
    15421 gattttggct aagcccaatt ggttactgac gatcattgcc tttttagttt cttcctttat
    15481 cttttatcgg cataaagaca atatcaagcg tatcagaaac catactgaaa gtcgaatccc
    15541 gtttggtttg aatagcagca agaaaaaatc ctgatacttt ttcattccaa agagataaaa
    15601 cgggagtgtg acaaatcgat gtcacactcc cttattactt acaggatagc ttttttacac
    15661 accttggtaa acggtgttcc ctgctaactt ctcggtcaca acctcttact tcactgtgat
    15721 ggaatatttt gtcttgaaga tttcatgggc acctagttga ttgatcccta ctttttccat
    15781 caagtttcca ctactgttca ccgtgtcagc gattccgcac cacggttcga tacaaacgaa
    15841 aggcgcttct tttggataag gagaccagat ccctacataa ggcatatctt tatagcttaa
    15901 agttacgcta tgggaagatt tttcacttcg aatggcgtac gcatttagac cccttgtttc
    15961 aaaaaccaag gcatcttgct caaaaagttc acgattcaaa gccagattcg tatttgtctg
    16021 acctaacgtc ttttgatcca tatcgatgaa tgggcctttc aatggtaggc gtaatcttga
    16081 tttcaatgga gaaaatgcca gatagaaatc ttcaaatgac aatccttctt caagaggtac
    16141 attgaaagca ggatgtccac cgatagaaaa gaacatttct ttttcaccgg tatttgccac
    16201 ttgataatga accgtgatgc cgtctcctcc taattcatag ctgatcacta attcaaaatc
    16261 aaatggatac ttttctaatg tctccggcgt actccttaag atgaaactag ccatttcttg
    16321 tccatgttca atgacttcaa aatccatatc ccgagcaaat ccgtgttgcc ccatttgata
    16381 tgttttccct tgataaacat actgatcatc ttttaaacgt ccaacaaaag ggaataaaac
    16441 cggtgcatgt ctgccccaat acgctggatc accttgccag atatactcta aaccatgttc
    16501 ttttgatttc agactgatca attccgcacc gtgttcagcg atttcggcga tcagctggtc
    16561 attttgaata ataacagtca ttgccattcc tccaacttcg acttactttt taaaatggga
    16621 aggctggaac aaacatttct atctgcccca gtccccttac ttctaataac tgtgttttgc
    16681 taactcgtct ttaaaacggg aattcaatac ttttaaataa gttcccttca tgcctaacga
    16741 acgagattca atgattccag ctgattccaa ttttcgtaaa gcattgacga tcacagaacg
    16801 agtgatgccg atactatcgg caatattaga agcagtcaga cgaccttcat ctccatccaa
    16861 tgcttcaaag atagcttgta cagccttcaa ttcgctataa gataatgtgt tgattgccat
    16921 ttggacagcc gttgcactcc gtacatctgc ttcgatgctt cgagacttct gataaaggat
    16981 ctgcataccg acaaccgtag ctccatattc tgctaagact agatcgtcat ctgcaaacga
    17041 ttgttccata cgagataaga taatcgtacc caaacgttcg ccagctccaa agatcggaac
    17101 gacagtcgtc agaccaaatg gatatttctc tcttgactct accggaaatg cagtaatatc
    17161 actagtaatt gggatattag cttcagtttt catcaactgt gccactgtat cagtataaga
    17221 ttcaggaaat tgtttctcaa caaacattgt tttgattcgt tcattgttca catcgtgacg
    17281 ttcattataa cctagtaata ctccgtcact tcctatgata taggtgttgc tgtcaagaat
    17341 accacctagt gtgacagcca ttttatcgta aggcaaatct gcttgcatgt caaaagtatt
    17401 cttttgctgc aaaagtgtgt ttatcttgcg ggttttcgtt agcaagtctg tcattgtcgt
    17461 cctccgattt tttataaaat atagcgactt aaatcttcat ttgccgcaat tgagccaagt
    17521 ttgtcatcca catatgcttc tgtgatcgtt atttctccca tttgcatatc tggtgcttca
    17581 aataatagat cttctagtag tttttccaaa atggtatgca gtctgcgtgc gccgatatta
    17641 tctgtgtcac ggttgacatc gaaagcgatt tgagcgatcc gttcaattgc ttcttttgta
    17701 aacgtaactg acacattttc tgtaccgatc aacgcgacgt attgttttac taaagcatta
    17761 tttggttcgg tcagaatctt cacaaaatct tcagctgtca aatcatctaa ttctacccgt
    17821 atcgggaagc gtccttgaag ttctggaatt agatcacttg gtttagacaa atggaaagct
    17881 cctgaagcaa tgaataggac gtgatctgtt tggatgatcc cgtattttgt gtttacttgt
    17941 gaaccttcga caattggcaa tatgtctctt tggacgcctt ctctggatac ttctccagat
    18001 tgctgtgatt tagaagtgat cttatcgatt tcatcgataa aaataattcc actttcttcc
    18061 gctaatttga ttgcctcact atggatatca gcatccttga ctaattttgc tgattcttcc
    18121 ttgatcaata actctaaagc ttctttgact gttaccgtcc gttccacttt tttcttcggt
    18181 gtcaaagcac ctagagtttc atttaggtcg atccccattt gctccaatcc attgttcatc
    18241 attggtgcag gtttcttttg gtcttcaact tcaatggtta cttcacgact atccagtaaa
    18301 cccttttgta gttgttccaa gactgtacgg cgattgattc gaatatcttc tgtcacttct
    18361 tcttgcggtt cagcggtatt ttgctgacta gcattaaaaa gattcatcat ttgttcaaat
    18421 tgattagtgg attgtttctg ttcttttttg ataccaggta ccaagatttt taccaaacgt
    18481 ttttctgcat tttttttagc acttgtgtat acacggctgt actgctcttt ttctacgatt
    18541 tggatcgcat tttctactaa atcccgaacc attgattcta catctcttcc gacataaccg
    18601 acttcagtaa attttgttgc ttcgactttg acaaatggtg cattgacgat ttttgccaaa
    18661 cgtcgtgcga tttctgtttt accgacccct gtaggtccga tcatcagcat attttttggt
    18721 gtaatatctt gttgcatttt ttcatctaac tgcaaacggc gatagcggtt acgcaaagca
    18781 acggcaacag atttttttgc tgcgtgctgt cctacgatat attcatctaa ttcacttacg
    18841 atttgtcttg gtgtttgttt taattcatac atatctactc acctcttaca gttcttctac
    18901 gataatatta tgattagtaa agatacagat atctgcggca atatttaacg cattttctgc
    18961 aatttctttc gcactcatgt cgttttgagc atagtttttc attgctcggg ctgcagccaa
    19021 cgcaaaattc cctcctgatc cgatagctaa gataccatca tctggtgtga taacttctcc
    19081 tgtacctgaa acaagaagca tttctttatc attcattacg atcagcatcg cttcaagttt
    19141 ttgcatagat tgctgtgtcc gccattcttg agctaattcg acagctgcgc gttgtagatt
    19201 cccgttatat tcgtttagtt tgccttcaaa tttttcttct aaagtaaacg catctgcaac
    19261 acttccggcg aaacctacaa caacttctcc attgtagata cgtcgtactt tctttgcagt
    19321 gcctttcatg acaacagatt cacccattgt tacttggcca tctccagcca tagcaaattt
    19381 cccgtctttt tcgacggcac agatagtggt tgaatgaaat ggtgattcga ccatgtttgt
    19441 ttcctcctaa atttgttctt ttccttattt ttacgctctt ggatggaaag aacgatagtt
    19501 tttttgtaaa ctttcttttg ttacatgggc atagatctgg gtagtcgata aattggcatg
    19561 tcctagcaat tcttggactg tccgcaaatc tgccccatta tttaataaat gagtagcaaa
    19621 tgtatggcgc agcatgtgag gatggatatc actatccaaa ctgctttttt tgatcatttg
    19681 attcaagaca tattcaattc cagtaggcgt gattggtttt ccatgatgat tcacaaaaac
    19741 gatatcatgc tcttcgtgat attttgtcat caatacctgg cggccttccc tgaaatattc
    19801 ttgcagagca tcttgagcaa aagaacctag aggagcatat ctctctttgt tccctttacc
    19861 atggatcaac atgacctctg aatcaaaatc aatgtctgat accgacaaac tgctacactc
    19921 acttaaacgg atgcctgacc cgtaaaggac ttccagtaaa gcgcggttcc tcaaatccaa
    19981 aggactatct cctgctacgc tgtcaaaaag tgcttgcatt tcattttcat aaaaaaaacg
    20041 tggcagtctc aaatttttct ttttgagatg aacgtaagaa aatggatttt cttttatcac
    20101 ttcttctttg agaagatact gataaaacga acgtaggctg gctatcttgc gactgataga
    20161 atttctgcta tagctaggac gatgatcagc taatgcactc aaatagacac gaaccgtaaa
    20221 atattccgcc ttcagcagat cagcgtctcc agattcctcc aaaaaatgtt tgaaatggag
    20281 aatgtcttct tcatatgctt ctttcgtttt ttctgaatat cctctttcga caatcaaata
    20341 acgcaaaaat ttttgttccc acgtggcttc tgtcattttc tcaccttcct tttgtcccag
    20401 agaataattt agcacagcgt ttataaaaag acaaataaat tgtcagaatt taaccaatat
    20461 ttctaagttt gttcacaatt ggcgcaattc ctcacatttt gtttgagaaa ttcttaagaa
    20521 aaacgcaaga aaaagagcga gactatccgt ctcaccctct tcatggagtt tccttactca
    20581 tttgggattg cagttttttc taattctgtt tttattgcct cattagcttt taaagctcgt
    20641 tgtgcaattg cttcatatct tgcttttttg tctcgaatgc gctctggcag ttcaggaaac
    20701 agaccatagt tggcattcat cggttggaaa tgttttcctt ccgcatgagt aatgtagtaa
    20761 gccatacttc caatagctgt ttcttgtgga aactcgactg gttccatttc ttttgctaag
    20821 cgtgcggcgt tgattccagc aagtagtccg ctcgctgcac tttcaacata gccttctaca
    20881 ccagtcatct gacctgcaaa gaacagatct tcgcgtttcg ttgattggta agtcggtttc
    20941 agcaattctg gcgaattcat aaagctgttt cggtgcatca caccatagcg aacgaattca
    21001 gcattttcta acccaggaat catccggaaa acacgttttt gctcgcccca tttcaagtga
    21061 gtctgaaagc ccacgatgtt gtataaagaa gctgcagcat tgtcttgacg cagctggata
    21121 acagcataag gacgtttgcc agttttagga tcttccaatc caactggttt cataggtccg
    21181 aaaagcatcg ttttgaatcc tcgctgtgcc attacttcaa ttggcataca tccttcaaaa
    21241 tatttttctt tctcaaaaga tttaagttct gccacttcgg cattgattag tgcctcatgg
    21301 aaagctttga attcctcttc tgtcatcgga cagttcaagt aagctgcttc tcctttgtca
    21361 tagcgggact tcaaatatac tttatccata tcgatcgtag ctttgtctac gattggtgca
    21421 gctgcatcat agaaataaaa accatctgaa ccattgaatg ctttgatgct ttctgctaat
    21481 ggatgagaag tcaaaggtcc tgttgctact acggtgattc cttccggtat ttcagtaatt
    21541 tcttcgttta tcactgttac taatggatgc tctttgactt ttcgggtaat tgtttcagaa
    21601 aaagaatcgc ggtcaacagc taaggcacca ccagctggca ctgctgtttc atctgccgaa
    21661 gtgattacta ccgaattcaa tcggcgcatt tcttctttca ataaccctac tgcattagcc
    21721 aaactgtttc ctcttaatga attggaacat actagttcag caaaattact tgtgtgatgc
    21781 gcctcagtcg atttgactgg acgcatttca tataaacgga cagggactcc tgcttgtgcg
    21841 atctgccaag cagcttcact tccggcaagc cctgctccaa caacatttac cattttcaat
    21901 gaaagaacct cttttctatt atttttggat gtcttcttcg taatctccat ttacacagac
    21961 tacttgttta ccgcctttga ctttcttctc gaccagatat ccgtcacatt ttggacaatt
    22021 tctgcccact ggtttatccc aagaagtgaa ttcacattct gggaaacggg aacaaccata
    22081 gaatagtctg tttttcttag attttcgttc aatgacttgt ccttcatgac atactgggca
    22141 agtcacaccg atttctttta cgattggttt cgtattccga caatcaggaa aattactgca
    22201 agcataaaac ttcccatatt tccctaattt tatcaccatc ggatgtccac agacatcaca
    22261 atcgaatcct gctggttcat ctttgatttg aattttttcg attttttctt ccgcattcgt
    22321 cagttctttt tcaaacggtt tatagaaacg atcaaccact ttgacccacg cttccgtgcc
    22381 ttcttcaatt ttatccaaat ctccttccat ttctgctgtg aaatggatat cgacgatttg
    22441 agggaagaat tcacagatta atgaattgac aatttctcct agttcagtcg gctcaaatct
    22501 tttttgtgtc aattttacat agtagcgtct ttggatcgta tcaagtgttg gtgcataagt
    22561 ggaaggtcgc cctaccccgt tttcttctag tgcacgaatc aacgtagcct cactaaaacg
    22621 tgctggtggt tgagtaaaat gttgttttgg ttcaatatca acagattgga ctacatcgcc
    22681 ttcttcaagt tctggaagaa tattttcttt ctcttctttg ccgtcatctc taccttccac
    22741 atacacttgc atgaatcctt tgaatttgat ttttgaaccg ttcgcaatga agatgacacc
    22801 attttgttct aatgtcactt tcattgtatc taaaatagct ggtgtcatct gactagccac
    22861 aaaacgtgac cagatcaatg tataaagttt caattgatct ttatctaaat attgtttgag
    22921 ttcatctggt gtacgaagca cactcgttgg acgcacagct tcatgggcat cttgtgcgcc
    22981 ttgagcattt ttgatctttc ggtgaccatg tctagaaaat tcttttccat acgtatcttc
    23041 aataaatgct gcggcctctg cttttgctgt atcggcaatc cgggtagaat cagtacgcat
    23101 gtatgtaatc aagccgactg ttccttgttt acccaaagtg attccttcat ataattgctg
    23161 tgctaccatc atggtttttc ttgttcgaaa gtttaactta cgggcagctt cttgttgcag
    23221 gctacttgta gtgaaaggat tcgcagggtt tcttttgcgc tctttctttt ctactttttt
    23281 aacttcgaag tctgttccat caattctagc agtgacttct tttacacttt gtgcatctgg
    23341 taatttcttt ttcttaccgt cgattcccca gaaatttgct ttgaatttct tgcgagcttt
    23401 tttaaaatta ccgtcgatgc tccaatattc ttctggaaca aattctcgga tctctttttc
    23461 acggtcaata ataattttta aagcgacaga ttggacacgt cctgcactta accctttctt
    23521 gaccttacgc cagagaatag gactgatcga ataaccaacg attctgtcta aggtacgacg
    23581 agcttgctgt gcatctacta aatctacatc gatcgttctt ggttccttaa aagctgcttt
    23641 gactgcgtct tttgtgattt cattgaagac cacccgattt ttttctttca gatccaaccc
    23701 aagtaggtac gctaaatgcc aagcaatcgc ttctccttct ctatccgggt cacttgccaa
    23761 gtaaactttt tgagcttttt ttgctgcggc tttcaggctt ttgatgacat cgccttttcc
    23821 gcgtatagaa atataatggg gttcataatt gttttcaaaa tcgataccca ttttactttt
    23881 cggtaaatct cttatatggc caacactggc cattacttta tagtttcgtc caagatattt
    23941 ctcaattgtc ttggcttttg caggtgattc tacaatcact aaatatttat acgccattac
    24001 tgaatggact cctttccatt gtcgtgttcc tactattaaa agaggattca tacaaatcgt
    24061 agctaatcat atccattcag aaaacgtttg tcaagaaaag caaatgaaaa gtatggtgtt
    24121 attctttaaa ttctgccaag atatcttcac ccgaaaccgt gcaaactgca ccgtcttgga
    24181 tcaaatgatg acatccggta gaatgttctg ttaaaatatt tcctggaaca gaaaaaactg
    24241 ttcttccaag atccaatgct tgctgtgctg ttatcagaga gccgcttttt ttcttggctt
    24301 caaagacaca tgttccttta gacaaagctg cgataatccg atttctcatt ggaaaacaat
    24361 gctttttcgg gccggattga ggaggatatt cactcaaaag aagatgatca tttgcaatca
    24421 cctcttgcaa gtcacgattt tcagcaggat agacttgctc tatccctgtt ccaatgactg
    24481 cgattgtccg tccaccatga gagattgctg cttggtgacc gtatgtatct atccctttcg
    24541 cgcagccact gacgatcaca tatccagctt ctatcactgg ttttagtaaa taataaactg
    24601 tttttttggc taaagcagaa gtgtgtcttc caccaacaac gcttaacatg ttacaagaaa
    24661 gtaaagatag atcaccatta taaaacagta caattggcgg ataggtcaag tgaagcagct
    24721 gagggggata tttgggatca aagcaagtga taaacgactg tttcgattgg attttgcccc
    24781 agttagcgtg aatttcctgc caacttttgc gaaacagctc ccggtgtttg gttattttac
    24841 ctatcttaat gatgtcttca aatccgattt ctttataagg atactgcatc atccagttag
    24901 caagtgccca ttttccttga ctactgattc cttttgtata agcaagtttc aataaatttt
    24961 cttctatttg atacatcata aaaccgcctt tcgtctctct ttctaataag atacgtaaaa
    25021 gcggctgttt tttattgtaa atattttttt acaggtgcaa aacttttacg atggattggc
    25081 gtaattcctt gtcgttcaag tccttctaag tgttcctttg ttccataacc tgcattatgc
    25141 gagaaaccat atccaggata aagcacgtca tattctttca tcaattggtc tcgatatact
    25201 ttagcaatga tacttgcagc agcaatcgac acagatcgtg catccccttt gattattttt
    25261 tcctgctgaa taggcaaatc caaggtcatc gcatcgatca acaaatagct tggtacaatg
    25321 gacaattttt ctactgcttg gatcatcgct aatttacttg cttcataaat attcacatca
    25381 tcgattgtct gctgatcaac gatcccgatc ccgattgcca gggctttttc ttgaacttgt
    25441 tgataaagaa gttctcgctt tttctctgat aattgtttgg agtcattcag ccctaatatg
    25501 atctcatttt tcggcaagat aactgcagct gccacgacag gtccagctaa tggtcctctt
    25561 cctacttcat caatgccggc aatccattgg tgaccttgtg cgtacccttg cttttcaaag
    25621 caaaacattt cttcatattt ttccttaatt aatgcttcct ttttcaatcg tcgttcaaaa
    25681 gaagccagtg cttgctgcac gcctttgcgt ggatcatttc ttaatgattc tagtgtagga
    25741 tcatctattc tctgtatgct tttcaatcgt tctttgatac tttggatgga ttcagtcatc
    25801 acttttttgc tccatttctt cgcaacgatc cagtgtgtat cgtccaagtt ttccttgacg
    25861 aatatcatgc acgactaatt cgctgccacg atcatagtct tctttatacc cacgttttgc
    25921 tgtaatatcc atcagtaatt ccggtgccaa tttttcttct tgctcgattg ataaaccata
    25981 acgatcgctg attcttcctg aataatatcg ggcaaaaaag tctaatccgt aaatcgctaa
    26041 atcatctaaa tggacaagct ggtctttgat cgcgcctgtc agcgctagtt ttttgccgat
    26101 ttcttcatct tcaaatttgg gccataaaat ccctggtgtg tctaacaatt ccaactcatt
    26161 acctaaacga agccactgct gaccttttgt tacgccaggc ttatttcctg tctgtgcaat
    26221 tttcttgcct actagtcgat tcatcaacgt agatttccca acatttggaa tacctaagac
    26281 cattgcccga atagcgcgag gcttgatccc ccgagcagca tctcttgccc gtttttcttt
    26341 caatgcttct ttagccgcag gtactagacc tttaattcct ttactttctt gtgccgtgat
    26401 agctaatgca agatggcctt gtttacgaaa atattcttgc cacagctttg tctgttgtgg
    26461 atctgccaga tccgctttat tcaataaaac aaggcgaggt ttttgctgaa tgatctgatc
    26521 tagcattgga ttacgagaag ataaaggtaa tcgtgcgtct accaattcaa atacgatgtc
    26581 cacatatttc attttttcag aaacttctcg tcgggctttt gccatatgtc ccggaaacca
    26641 ttggatggtc attgttctct ccattccttt cataccggaa tattccccgg ctttacttgt
    26701 ttttttcttt ttcaatataa attcactttt ttattatctt aattgtcaaa ttaagttaga
    26761 caaatcatca atacttacgt aactcaaaaa tacttccaaa ggtgttcgat aattcagtga
    26821 ttttctagga atattatttc gtttcgatgc gacagattga ataaaagatt catctactga
    26881 attgaaatcc atagatttca ataaaccatc tctacgtaac aatccgttag aattctcgtt
    26941 taggcctctt tgagacggcg ttcctggatc agcgaaataa atggcaatat cattggcatt
    27001 actgatctgt ttccaatttg aaaattcctt tccacaatca aaagtgatgg atttgaatag
    27061 atttttcggt acagattcaa accaatgatt taatttgttt tcaatatcaa tcgcttgtct
    27121 accacacggt ttcaatgtga tgataacttt tgataatcgc tcaactaagg taattacagc
    27181 acttttatgt ttcaaaccta cgatagtgtc accttcaagg tgaccaaact catttgagaa
    27241 ttggctataa tctttttcac gttcatgaat agagcgacgg aaagcttgtt ttccacgtct
    27301 ttcttgatgt ccatttggtt tacgcttgcc tttcatcggt aagtcagaag gattaaatag
    27361 cccctttttg aacatacgat aaatggtacg agcagaacaa cgaataggaa acgctgcacg
    27421 accaacaatc acatcgggtg tccatccttg aacaaccttt ctttgaatat attctgattg
    27481 ttcctcaggt aaaacaagcg ggcgtctacc acagtttgat ttgtttttct tatactgttg
    27541 atagtactct aaggctgatt ttccttgctt gaagaacagg tatactttat ggatcgtttg
    27601 tcttgaacga ttcaagaaat gcgcagtttt cgcaacagat tgatttattt tgaaataaga
    27661 ctctatcatt acaagttcat ccgttgtaag atgggtatag gtcatttgta ctcactcctt
    27721 ataattcttt ggacggaact attttgagtg tagcacaaat gactttttta gttgtctagc
    27781 ttaattttac aatcggcgtt ataaagaaat tccatctatt agttaagtga aagtgaacca
    27841 gtcctcattc tatcacatct tcactttttt gatgatgcaa atttttattt tggtttctat
    27901 atatgaatct aaatttttga cagcgtttcc taaataagag atgatagacg aacaaaacag
    27961 aaaggagacg aaacaaatga atagtatggt
//
LOCUS       DAXLPC010000029        27102 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.029, whole genome shotgun sequence.
ACCESSION   DAXLPC010000029 DAXLPC010000000
VERSION     DAXLPC010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27102
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.029"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(58..510)
                     /locus_tag="ACF3UE_001229"
     CDS             complement(58..510)
                     /locus_tag="ACF3UE_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3634657.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(975..1343)
                     /locus_tag="ACF3UE_001230"
     CDS             complement(975..1343)
                     /locus_tag="ACF3UE_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFD3634658.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            1493..1975
                     /locus_tag="ACF3UE_001231"
     CDS             1493..1975
                     /locus_tag="ACF3UE_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFD3634659.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            2012..3022
                     /locus_tag="ACF3UE_001232"
     CDS             2012..3022
                     /locus_tag="ACF3UE_001232"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFD3634660.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(3137..3850)
                     /locus_tag="ACF3UE_001233"
     CDS             complement(3137..3850)
                     /locus_tag="ACF3UE_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634661.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(4023..4630)
                     /locus_tag="ACF3UE_001234"
                     /pseudo
     CDS             complement(4023..4630)
                     /locus_tag="ACF3UE_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
     gene            5114..5341
                     /locus_tag="ACF3UE_001235"
     CDS             5114..5341
                     /locus_tag="ACF3UE_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFD3634662.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            5357..6523
                     /gene="hemW"
                     /locus_tag="ACF3UE_001236"
     CDS             5357..6523
                     /gene="hemW"
                     /locus_tag="ACF3UE_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFD3634663.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            6757..7800
                     /gene="hrcA"
                     /locus_tag="ACF3UE_001237"
     CDS             6757..7800
                     /gene="hrcA"
                     /locus_tag="ACF3UE_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFD3634664.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            7894..8457
                     /gene="grpE"
                     /locus_tag="ACF3UE_001238"
     CDS             7894..8457
                     /gene="grpE"
                     /locus_tag="ACF3UE_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFD3634665.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            8508..10337
                     /gene="dnaK"
                     /locus_tag="ACF3UE_001239"
     CDS             8508..10337
                     /gene="dnaK"
                     /locus_tag="ACF3UE_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFD3634666.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            10488..11654
                     /gene="dnaJ"
                     /locus_tag="ACF3UE_001240"
     CDS             10488..11654
                     /gene="dnaJ"
                     /locus_tag="ACF3UE_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFD3634667.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(11736..12365)
                     /locus_tag="ACF3UE_001241"
     CDS             complement(11736..12365)
                     /locus_tag="ACF3UE_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3634668.1"
                     /translation="MGQLSDNQQLCQERINPLLELLERVFSYYGQALLTVHRQQIIIL
                     VNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSFLHAKQVCEWIAF
                     HQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLFKKTLACFSKNNG
                     SIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLLVQT"
     gene            12377..12550
                     /locus_tag="ACF3UE_001242"
     CDS             12377..12550
                     /locus_tag="ACF3UE_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634669.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(12595..13332)
                     /locus_tag="ACF3UE_001243"
     CDS             complement(12595..13332)
                     /locus_tag="ACF3UE_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD3634670.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(13334..14836)
                     /locus_tag="ACF3UE_001244"
     CDS             complement(13334..14836)
                     /locus_tag="ACF3UE_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFD3634671.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            15095..17089
                     /gene="uvrB"
                     /locus_tag="ACF3UE_001245"
     CDS             15095..17089
                     /gene="uvrB"
                     /locus_tag="ACF3UE_001245"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFD3634672.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            17099..19915
                     /gene="uvrA"
                     /locus_tag="ACF3UE_001246"
     CDS             17099..19915
                     /gene="uvrA"
                     /locus_tag="ACF3UE_001246"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFD3634673.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            20178..21443
                     /locus_tag="ACF3UE_001247"
     CDS             20178..21443
                     /locus_tag="ACF3UE_001247"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFD3634674.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            21447..22178
                     /locus_tag="ACF3UE_001248"
     CDS             21447..22178
                     /locus_tag="ACF3UE_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFD3634675.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            22313..23197
                     /gene="rapZ"
                     /locus_tag="ACF3UE_001249"
     CDS             22313..23197
                     /gene="rapZ"
                     /locus_tag="ACF3UE_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFD3634676.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            23194..24192
                     /gene="yvcK"
                     /locus_tag="ACF3UE_001250"
     CDS             23194..24192
                     /gene="yvcK"
                     /locus_tag="ACF3UE_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFD3634677.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            24226..25161
                     /gene="whiA"
                     /locus_tag="ACF3UE_001251"
     CDS             24226..25161
                     /gene="whiA"
                     /locus_tag="ACF3UE_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFD3634678.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            25704..26354
                     /locus_tag="ACF3UE_001252"
     CDS             25704..26354
                     /locus_tag="ACF3UE_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634679.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            26541..>27102
                     /locus_tag="ACF3UE_001253"
     CDS             26541..>27102
                     /locus_tag="ACF3UE_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HFD3634680.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT         8934 a         4570 c         5721 g         7877 t
ORIGIN      
        1 aaaaaaatag cgctagaatt tccaacatct ctggaatttc tagcgctttt taattgttta
       61 agatacaagg gaaatatctg tctggatcaa taatttttca ttgatccatt gactaaagtt
      121 tacgacataa ttgaagttac caccgattag tatctccgca tgattgtctt tataaagatc
      181 gtattgtaaa agacggtctt ttttatttgc gtaaacatcg ttatggtact ggactaattg
      241 ttctcggaat tgattgattg ctgtaaaatc acgatattga aggttgaaac gcatcgtgat
      301 tggtgcattt agcatgaatc gctgcatttc ttttgctgct tcctctgctt gatctccgta
      361 taggaactca aaaagattac gttcagaaaa tttccattgc ccgccaacct ttgttccttt
      421 tagttttcct tcatgaagat aatttctgat agaacgtgta gtaacaccta attgttcggc
      481 taattcattt actgagtaaa aatctttcaa tgttcaccct cctatgtgaa tggttctact
      541 gacttagttg atatttgctt aatcacgaaa tgtagaaaga acgattttaa ttaaggtcat
      601 tgtaaaaatc aagtcagaaa attctaactt ttatttctct aaagaaattc gttctctcct
      661 aaagtgatat tatatttaaa tatacctgaa aataatgggc agtattatga aagatcactg
      721 atattttctc gtattttttc cttattcaaa agttttgcag gaaaattgct gaaaaaataa
      781 ttttactaag tagaaaattc aaagccattc aatcagtgat ttttttcagc acaagaaaga
      841 ctccttataa aaatagcaga tactttgtca attaagtgtt taaccaggga tgataaaaag
      901 gataggattg aacaaaacct gtataaggtg atgaatagtt tcctcgccag taaaaggttt
      961 attcgtataa agctttatcg ccaaaattta tcatgacctt ttttatcttc aatattaaat
     1021 gaaatcaatt gttcaatcaa ttcccagttg attacacttt tccaaggaac tttgatgacg
     1081 ttatccgtat atacgtagcc tgcttcttgg atattttttt caagggcacg aatcgctgct
     1141 ttttccggtg cgatagaaaa atgattttta gcaaaactaa atgcaataat aaaggtacca
     1201 tggtcagtaa acataggttg gttccatttt acagttgtgt ctagctgggg atacgtttct
     1261 gttatcttag caaaaaggtc tttgatcttt tgttgatgtt ctttttcttt gatttgattg
     1321 atgatcggct gaaatttttc cattctaaaa cgcctccatt aagtggtttg atttatttta
     1381 ccagaaaaac aatagttatg tataaaaaac gaacaaaaca caagtaatgt tgtaaccgct
     1441 atatttatat gataagatgt ctcaaataat aaaatagaaa agagacataa aaatgattga
     1501 cttggcaaag aaattcttac acgaaaatat atattttgag ttgtatcatc atcgagccat
     1561 ttatacaaat gaagatgctt tggtaataaa gaaagaacaa ggatttacag gtacagagac
     1621 caaaagctta ttcttaaaag ataaaaaaga taataactac gtatatctga cttttactac
     1681 gaaacaaacg gatttcaaag cattagggaa gatcgtcggt aaaaggcttt ctattgtttc
     1741 atcagaacgc atggaagaac aaacgggaca aaagcagggc gctgtttctc cgtttggtta
     1801 tgaaaaacag attccgatta ttattgatga agagctctta tcaaatgaaa aacttgtttt
     1861 tgcaccaggt agaccagatc aaacgatggt catccaaacg gttgacttaa acaaaatcat
     1921 ccagctactt gagatgccga tatttttgat gccggcaaac gaaaaaaaca attaaccaag
     1981 taaaatagtg catacttgga ggtgaagcaa catgataagt tatccattat tagaaagaaa
     2041 tgcaacgatt ggggttactg caccatcctc aggcgtatca gaggaacacc attcgttact
     2101 cgaatcagct ttaaagagaa tggaagaaaa atctttccaa gtagttactg gaaagacgct
     2161 ttggacgcaa gataaggaaa aatcaggtcc agcaagaaaa cgagcagatg aattcaatca
     2221 aatgatgcaa gatgaaaata tccaaatgat ctttccgact tggggaggag aattattgat
     2281 tgagattctc gattttgtcg attttgatgc tctacaacca aaatggatag taggttattc
     2341 agatattagt acgttgctac ttgctgtcac attaaaaaca gggatagcca ctgcacatgg
     2401 aactaacctt attgatttaa gaggagagta cttggatgaa acgacagcaa tgtgggaaag
     2461 tgtactgaaa acaagagaag gagaatcgat tctacagcaa tcttctgaaa agtatcaaaa
     2521 agtgtggccc catgagcatt catcatcttc tgttttccat ctcactgaac caacaaattg
     2581 gcaatcagtc agcggagatg cagtaaggat gaagggacga ttattaggtg gttgtattga
     2641 tacgatcagg catttaatcg gtactcctta tggagatgtc caatctttta aaagaaagta
     2701 taatgatgga aagccgatct tgtggtttct agaaaactgt gagctatcgt cagttgattt
     2761 aagaagatca cttgttcaga tgaaactggc aggctggttt gatggcagct cggggatcat
     2821 gttcggtaga agtgcggcag aggatttgtt agattataaa atgaaggatg tatacgaaga
     2881 tctgtcaaag gaattaaaac taccgatctt gtatgatatt gattgtggtc atgtaccgcc
     2941 acaactgaca ttgattaatg gtgcctatgc agaagtagcg gtagaagata gaaaagcgac
     3001 tgttttgcaa acgtttattt aaaaaatttt ttcctgcctt ggagtctatc aaagaccaat
     3061 aaatctaaat agaaaagaaa gtgaaagaag ctgacaaaat gctgtcagct tctttttgta
     3121 taacatatta gaaagtctaa ttatctataa ctgtcacatc gattaactgt ttcacgtcat
     3181 tgggatttcc tgtaggaata gctactacag atgcattatc aatgatttct tgagttgttt
     3241 ctctaatgaa cgctggataa gatgtttgat ctgcaggcat ttgccaatgt gaaggaactg
     3301 gataactagt gattgtcccg tcatggttac ttgaatacac taaaactccc tggtaactgt
     3361 atttcccagt gagcataacc acatctttcg gatagactgc actccctgca tcataagggg
     3421 cgataggtgt tcctgcagga taatgaataa catgtaattc gaaatcaccc gatgtatctc
     3481 taaaagtatt acctctaata gctagccaaa cacgtgcgta ctcaatttgt agatcagaat
     3541 atcctgctaa cggatctatt gactgagaag actgtgagga ggttgtgtct attgttgaag
     3601 aagaaatatt tgtctcaact gtactactag atgtagaaga agtattgggc tctgagactt
     3661 tactgcttgt tgaagatgta ttcgtttcag tagaagctga tttctgagta cttgattttt
     3721 cagctgaact ggtttgtctg attgaacttt tgtctgtggt cgcagatgga tcactatttt
     3781 ctttactagg agacgtacat cctacaagga ataaagagac caacaataaa ataaaaccta
     3841 actttttcat ataaaatacc tcattatttt tttaatacca gtatagcata atcctgaatt
     3901 tttgaatccg taaaaccttg tctatgaata taaatagagt gtatcttctt tgataaatgt
     3961 cagaaaaagt gtgacaaata atcatcagta aaattacttg tcacactatt gataaggagt
     4021 atttaattga agagaatgat taggagaaag gatctccgta ctttttatag taatcataga
     4081 atccaagttt gtatagacga atcgtttttt ctcttatttc ttctgtttca aaatggactg
     4141 cttgaagaat caagtctgtg aattctatag gagctgttcc attcgcagta atcaaattac
     4201 gatctttcac agcttgttgt tctataaaat cttctttatt ctgataattt tccgattcta
     4261 accaaggaaa ttgcgcattt ccggtgtgtt tgtaaccttg caataatccg ctctgagcta
     4321 aataatcaac tgccccacaa atagcagcta ctggtacgtc tgtttttaac aatttatcga
     4381 ttatttgata taaatgatga ttttttatgt cccatgaatt gccaccgatc ataataaaaa
     4441 ggtcaacttt ttcaggtatt tgttcgatta agtaatcgat ttttgttttt aatcctccaa
     4501 tggaagtgac ctctgattgg atagaagcag ttttgttttg ccatttctca ttttggttta
     4561 gtgtgctagt aatataagca ccttcccaat cggcatattc ctctaataga aacgtaatcg
     4621 cagttttcat tttcaagctc tcctttacta tctataacaa ggacaacagt tttaacctac
     4681 agacattcat taaaattggg tagcgacagc gaaaacaaca attcttaagt tttagacaga
     4741 gtatacagat agtcaactta attaaatacg aactaaataa aaatgacagg taatcatttt
     4801 tgtttaccag cattataaca ttttgcatac atggatgaca aaagaaccaa ttcccacttg
     4861 cttgagtaca atattaaaag aaactggaag gcaaaaagta attatagaaa cgaaaaataa
     4921 atcatatcgg gcactcagac atgaaaacaa ccctagagat atataactag gtaaccagtt
     4981 taatgaaaga aaaaatcatc caagaagtcg attcttggat tttttagtgg atttgttcgc
     5041 caaatacgtt tagtatgcgt atatgagagg ttgtaagcaa agcgttgtgg tctgagcact
     5101 taaggaggaa tctgtgaaaa tagcttttca tatttttgca gattttgact taatgccgaa
     5161 ggtcagcttt gcgattaccg tttatcgaga ggctgtaaaa gcaccgtgta gctccgatga
     5221 caataagcaa gcatttttag agctaggttt ccttgattct aaatatgcgg cttatttcaa
     5281 tgagttggtg cttgaacgcg attttaagaa ggtcgaaaac aggcacgact tttcgacgta
     5341 aggagaaaga atttcaatga tagaaacaat aaatcccgca gaaaacaagg tttctgcgta
     5401 cattcatatc ccattttgcg agcatatctg ctattactgt gattttaata aagttttttt
     5461 agaagggcag ccagtagatg agtatgtgga aatgctgctg aatgaaatga aaataatgct
     5521 agaaagtcat ccgacagcga atttagaaac actttacgta gggggcggga caccaacttc
     5581 tttatctgct aaacaacttg atcgactgtt atcaggtgct agagagatcc tgccttttca
     5641 aaatggtaat gagtttactg tagaagcgaa tccaggtgat ttgacccgtg aaaaacttca
     5701 agtaatgaaa aactatggcg tcaatcgttt atccatggga gtgcagacat ttgataatcg
     5761 cttattgaaa aaaattggac gtaaacacac cgcagaagat gtgtatcaaa ctatgcaatt
     5821 tttagaagca gaaaatttta ccaatgtaag catcgatttg atttatgcat taccgggaca
     5881 aacactagaa ggatatctgg atactttgga aaaagctttg gctttggatc tgcctcacta
     5941 ttctttgtac tcattgatcc tcgaaaacaa aacaatgttc atgaactggg tacgacaagg
     6001 aagactcgaa ctgcctgatc aggaaacgga aaccagaatg tttgaagaga cgattgaagc
     6061 aatggaaaag catggacgtc accaatatga aataagtaac tttgggctct ccggacatga
     6121 atctcaacat aacctcatgt actggaacaa tgaccactat tttgggtttg gagctggtgc
     6181 tagcggttat cttggagata ttcgttaccg caacaaagga ccaatccaac actatttacg
     6241 cccattacga gcaaatgaac gcccggtatt ggaagaagaa aaattgacac gaaaaaatca
     6301 aatagaagaa gaaatgttct taggactaag aaaaaaaaca gggattacta aaaaacattt
     6361 ctatgatcgc tatcaaaaaa caattgaatc ggtgtacggt gatgtgctaa gggaattaga
     6421 gcaagaaggg ttacttgtta atgaagaaga ccgtgtttat ttgacaccaa gagggacctt
     6481 tttggggaac aatgtgtttg agcgcttttt gtttgaaaaa tagtttaaag aatatttgtt
     6541 ttttatctga atttaaataa aaaaagttca aaaatacaat aaaggactat tgaaacgttg
     6601 atataactgg atttacatca attatttaga attagcactc ttgtgtttag agtgctaaaa
     6661 aatggagtct ttctcttgac aggagaaggg cttcttgcta tatttataag tggattagca
     6721 cttagaatat atgagtgcta atgagaggtg aggaagatgt taacaaagcg acaaaacgac
     6781 attttacgtc tgatcatcca acactatacg agtagtggcg tgcccgttgg ttccaaaaca
     6841 ttgatgtctg agggagtcaa ggccagctca gcaacgattc gcaatgatat gaaagcatta
     6901 gaagatgaag gattgctgtt gaagactcac tcttcttctg ggcggattcc atctgcttta
     6961 ggctatcgtt attacgtgga tcatttgtta aaacctgctc gcgtagcaga agatgatttg
     7021 ctgctgattc gtcagtctct aggcagagaa tttcatgaaa tcaatgagat tattaagcaa
     7081 tctgctgaga tattatctga gctgacaagc tatacgactt tttcattggg acctgaaata
     7141 aaagaccgcc gactgactgg ctttcgtatc gtacccttga ataatcgaca gattattgct
     7201 atcgtcgtaa cagatatggg gaatgtagaa agccaagtgt tcactcttcc cgaatatatg
     7261 ggaagtcagg aactagaaaa aatggtacag attgtaaacg accgtctagt cggagatcct
     7321 ctgatgacgg tgtaccataa acttcgtacg gagattccga tgattcttca taaatatttc
     7381 caaacgacag aagggatgtc tcagttattt gacaccgttc ttggtcatgt ttttgaagat
     7441 aaggtttatg tcagtggaca aatgaatctc ttggattatg agccccgtca agatcttgat
     7501 cagttcaaat cgatgttttc ttttatgaaa gactcagacg gacttacaca aatgatcact
     7561 ccgatggata gcaatattca tatcaagatt ggtgctgaat taggcaatga tttattgcag
     7621 aatatgagta tgattcaagc aagttacgag atagatggtc atggaagagg tacaatagcc
     7681 ttgttagggc ctactagtat gccttattct cggatgttcg gtctagtcga tgtttatcga
     7741 agagaactag cagctaaact tgctgattac taccgttcgc ttgacttgtc aaactcgtaa
     7801 tgtgaataac gaagctattt gcagctgatc gttctctctt tcttagtaag agcaatcaaa
     7861 cagctgactg aataatgaaa ggaagactgt atcgtgaaag aaaatcaaga agaactagat
     7921 aaagaaatga cagatgctca gccagaaccg gaaatcgatg tcgaagctgc agaagattcg
     7981 ggtatttcag aagctgaagc ggaagaattc gaaacagcga aattaaaagc tgagttagaa
     8041 gaaatggaag ataaatactt gcgggctcgt gctgaaatcg caaatatggc aaatcgagga
     8101 aaaaatgagc gtgagcaatt acaaaaatac cgttcacaag atttagccaa aaaattactt
     8161 ccatcaattg acaacctgga acgtgcatta gccacagaag tgtcagatga tcaaggggca
     8221 ggtttgaaaa aaggcgtgga aatggtcttg gaaagtttgc gtaacgcact ggaagaagaa
     8281 ggaattgaaa aaatccctgc taaaggagaa gcctttgatc ctaatcttca tcaagcagta
     8341 caaactgttc cagcgactga agatacacca gccgatacga ttgtagaagt actacaagaa
     8401 ggctacaaat tacatgatcg cgtgttaaga ccaaccatgg tcattgttgc acaataattg
     8461 tgcggatata aaacttacac tttcaattaa agaaggagac gttaattatg agtaaaatta
     8521 tcggtattga cttaggtacg actaactctg cagtagcagt attggaagga aacgaagcaa
     8581 aaatcatcgc taacccagaa ggaaaccgta caacaccttc tgttgtatca ttcaaaaatg
     8641 gagaaatcca agtaggggaa gttgcaaaac gtcaagctgt gacaaaccca aatacgattt
     8701 catcaatcaa acgccatatc ggtgaagcag gttacaaagt agatgtagaa ggtaaatcat
     8761 atacaccaca agaaatctca gcaatgatcc ttcaatatat caaaggattc gcagaagact
     8821 atttaggtga aaaagtcgaa aaagcagtta tcactgtgcc agcttacttt aatgatgcac
     8881 aacgtcaagc aacaaaagat gctggtaaga tcgctggtct agaagtagaa cgtatcgtca
     8941 atgaaccaac tgcagctgct cttgcctatg gtttagataa aacagatcgc gacgaaaaaa
     9001 tcttagtatt cgaccttggt ggcggtactt ttgacgtatc tatccttgaa ctaggagacg
     9061 gtgtctttga tgtattgtca acagctggcg acaaccatct aggtggggac gactttgata
     9121 acaaaatcat cgactacatg gtagcagaat tcaaaaaaga aaacagcatt gacttgtctc
     9181 aagacaaaat ggctttacaa cgcttgaaag acgctgctga aaaagcgaaa aaagatttat
     9241 ctggcgtatc aagcacacaa atcagcttgc catttatcac agcaggagaa tctggaccat
     9301 tgcatttgga aatgacattg acacgtgcaa aatttgatga attaacagct gacttagtag
     9361 aacgtacaaa agtaccagta cgtcaagcgc taaaagatgc aggtttatca caatcagaaa
     9421 tcgacgaagt tattttagtc ggtggatcta ctcgtatccc tgcagttgta gaagcagtac
     9481 gtaaagaaac aggaaaagaa ccaaacaaat cagttaaccc tgatgaagta gttgctatgg
     9541 gtgctgctat ccaaggtggc gtgatcactg gtgatgtgaa agatgttgtt ttacttgacg
     9601 ttacaccatt gtcattaggt atcgaaacaa tgggtggagt gttcactaaa ttgattgacc
     9661 gcaatacaac gattccaaca agtaaatcac aagtattctc aactgcggca gataatcaac
     9721 cagcagtaga catccatgta ttacaaggtg aacgcccaat ggctgctgac aacaaaactc
     9781 taggaagatt ccaattgaca gatattccag cagctcctcg tggtattcca caaatcgaag
     9841 taacattcga tattgataaa aacgggattg taaatgtatc tgcgaaagat ctaggtacac
     9901 aaaaagaaca aaaaatcacg atcaaatctt cttcaggtct aacagacgaa gaaatcgaac
     9961 gtatggtaaa agatgcagaa gcaaatgcag aagcagataa agctcgtaaa gaggaagttg
    10021 acctacgtaa tgatgtagat gcattgctat tctctgtgga caaaacattg aaagaattag
    10081 aaggcaaagt ggacgaagaa gaagtgaaaa aagcagaaac agctcgcgat gaattgaaag
    10141 ccgctgttga agcaaacaac atcgaagaaa tgaaaactaa acgcgatgca ttgaacgaaa
    10201 tcgttcaaaa cttgactgtt aaactatacg aacaagcggc acaacaacaa gctcaagaaa
    10261 acccagaagc agctcaaggc ggagcagatg atgtcgttga tgctgatttt gaagaagtcg
    10321 atggcgacga taaataatca gttcactgaa tttcgagaga aggccaaagt tgctactttg
    10381 gctttttctt ttgaaaaata gtttgaagta tcggtttttg tttcaaacaa aatatgatat
    10441 gataacaagc gacgtgaaaa tgatgagaac caataggagg aaagcctatg gcaacaaaac
    10501 gtgattatta tgaagtctta gggctctcaa aaggagcatc agaagatgaa ataaagaaag
    10561 cttatcgtaa gctttcgaaa aaataccatc ctgacatcaa taaagaacct gatgcggaag
    10621 aaaaattcaa agaagtatca gaagcatatg agattttaag tgacccgcaa aaacgcgctg
    10681 catatgacca atacgggcat gcaggcacag atccaaatta cggtgctggt ggagctggtg
    10741 gcggatttgg tggattcggc ggcttctctg gtggcggctt cggtggtttt gaagatatct
    10801 tcgactcttt ctttggagga ggcggtcggt cagtcgatcc aaatgcgcct cgtcaaggtg
    10861 ctgatttgca atatacggtc gacttgtctt ttgaagaagc gatttttggt gtagaaaaag
    10921 aaatcaagta taatcgggaa gaaatctgtc atacttgtgg tgggaacggt gcaaaaccag
    10981 gcacacaacc aactacttgt cataaatgtc atggtgcagg tacgattaat gtagaacgcc
    11041 aaacaccact tggacgagtg atgagccgtc aaacttgtga tgtttgtcat gggacaggga
    11101 aagaaatcaa agaaccttgt ccaacctgtc atggctcagg acatgagaag aaagcacatt
    11161 cagttaaagt gaatgtacca gctggtgtag aagaaggaca acaaatgcgt ttagctggtc
    11221 aaggagaagc tggagaaaac ggcggaccat ttggtgattt gtatgtggtc ttccgtgtag
    11281 aagaaagtga tatctttgat cgtgaaggtt ctgaaattta ctatgaattg cctttaagtt
    11341 ttgtacaagc agctttgggg gatgaagtcc aagtaccaac tgtccatgga gatgtgaaat
    11401 tgaagatccc tgctggaaca cagacaggta cgaacttccg tttacgtgga aaaggcgctc
    11461 cgaagttacg tggtggtgca acaggcgacc aacatgtcaa agtaaaactg atcacaccga
    11521 aaaatctaaa tgaacaacaa agagaagcat tacgtgcatt cgctgaagct ggcggcatca
    11581 aagttgaaga acagcaagaa gacggtttct tcgataagtt taaagatgct tttggcggga
    11641 aaaagcggaa gtagtttttc tagtaaaaac gctaagtcat taataattaa aaaccagacg
    11701 aacaatcata tgttcgcctg gtttttttgt agttgtcatg tttgtaccaa caaaaaagcc
    11761 agctttagaa tatgataatc gtcatagttt ctaggggtat aaccagtgag agaatggaac
    11821 ttgttcaatc gatattgcaa ggtgttttta tgaataaata attcttctga gcaatttttg
    11881 atgcttccgt tatttttact gaagcatgcc aaagtcttct tgaacaaatg tacttcttct
    11941 tctgtcaggc ttttcaaaat acgttttaca tataatgttc gttgatctga cgggattgct
    12001 ggtaaaacga tcccgaggtc taaatcttca aaaaagcgga tctcgttcac agattgatgg
    12061 aaagctatcc attcgcaaac ttgtttggca tgaaggaaag attgcggtgt ctcttgctct
    12121 gtataacaaa gcgacccaat tccaaagttt agctgtaact gatacatttt attaaacttt
    12181 gtctggattt tatcaagcaa tgatagcaat gaggctctgg aaatccgatt gactaggata
    12241 atgatttgtt gtctatgtac agtgagcaaa gcctgtccgt aataagagaa gaccctttcg
    12301 agcaactcca ataaaggatt gatccgttct tgacacaatt gctgattgtc agaaagttgt
    12361 cccacaacta cataatatgg agaagaaaaa tcaagctcaa ttaagtgagg gtggtatcga
    12421 ctatgtactt gatatcatca atgaaccgat ggtactttct tatgcgatgg aacaggtaga
    12481 gcgattgctt gtttgtgcag gaaaacaagc gatgcggctg atacgattag gtgagaaaat
    12541 aagaagataa aaatacacgg tcccttcatg gcgaccgtgc atttttggtt tttattaaat
    12601 atttaatact ttattcaaga aatcttttgt ccgttcattt tgcggatttt caaagatttg
    12661 ttgaggcgtt ccatcttcta aaaagtttcc gtcgtcaatg aacatgacgc gattggccac
    12721 ttctttagcg aaccccattt cgtgcgtaac gataaccatc gtcatacctt gttctgctaa
    12781 ctttttcatg acgttcaaga catcaccgac catttcagga tcgagtgcag aagtaggctc
    12841 atcaaaaagc atgatgtcag ggttcatcgc tagagcacga gcaatagcca cacgctgttt
    12901 ttgtccacca gaaagcattt caggatacat atctttttta tcttctagac caactgtctg
    12961 cagtaatttg attgcttttt tctctgcttc ttctctagat tctttcttca ggtccatcgg
    13021 tgctaaaatg atgttttcca aaatagaaag atgagggaat aggttaaagt gttggaatac
    13081 cattccgata tgttgtctca ccaagttgat atctgtgctt ttatccatca agtgggcgcc
    13141 gtcaataata atttcaccgt cagaaggttc ttctaaacga ttcaagcaac gcaagaatgt
    13201 actttttcct gaacctgaag ggccaatgat acagacgaca tctccttcgt tgatggatac
    13261 attgatgtcg tttaatactg tgttatcgcc gtattttttg actaaatgct caactaagat
    13321 tttttctgcc atcttacttc accttctttt ctaaaacttt tgctaatttt gtcaatgctg
    13381 tgatcaaaat caagtacatg atcgcaatga tcaagtaaac atacgtactt tgtgttgtac
    13441 gtgcaacaat gatcttacca gtttgcagca attcgactac accgattgcg gaaatgatcg
    13501 ttgtgtcttt taatgagata acgaactgat tgacgaatga tgggatcatg atgcgtatcg
    13561 cttgcggcaa aatgattttt tgcattgtcc gattataaga aagacctaaa cttctggaag
    13621 cttccatttg tccgacagga acggcgttga tcccgcctcg aacaatctct gcgatataag
    13681 cacttgcgtt aagagtcaag gtgataacac cagcaaggaa gtcaggaatc gtaaatccaa
    13741 cgataccagg caacccaaag aaaataaaga acgcaagaac catcattgga attcctcgga
    13801 tgatatcgac ataaatacta gcaattgtgc gaagagcgcg tattggtgct acactgaata
    13861 atccaaaaat cacaccgatt actatagcca aagcaaagga gatcaaagtt aggagaattg
    13921 ttctccaaag tcctttcaac aatgcttgat agttgttttg gataagtcca agaaatgttg
    13981 attcatcagc agtggaagac tcactggaag tttctgaacc atccgctaca tattctttaa
    14041 taatcttatc gtattcgcct gttcttttta attctttcaa tccttcattg aacatattaa
    14101 gaagctcagg attttgtcct tttttaacgg caaatgcata ttttccgcca gattcttttt
    14161 tgatcggtgt ttccaattct tgtccttgtt tgatcgcata accgattacc ggataatcat
    14221 ccatcattgc atcgattgcg ccaactttta acccgtcgta caattgatca gcagcatcaa
    14281 aatatttgat agaatagcca tattcagatt catggtcgct taaaaattca gcactttcgg
    14341 taccaacttt tgctccgact gtttttcctt tcaaatcttc ataagacttg atcgaagtat
    14401 ctcctttttt gacagctaat tggatcccgc tatcaaagta agaatcagaa aaatcatagc
    14461 ttttctttcg ttcatctgtt acagtcattc cggcaatcat tccgtctgct tgtcctgatt
    14521 ccaaagcttg caaagcagca gagaaaccac ggtagtccat tcggatgtta aatccttgca
    14581 gtttggcgat gttttccatc aattttacat cgatgccttc gtactcgccc tttgcgtttt
    14641 gaaattcaaa tggagcaaaa gcagagtcac tggcaattac gtatacgtct tttttgggct
    14701 ctattttttg cattgtctcg cttgtgcttg actctgccgt tgtagtgttg tcagcttgtg
    14761 caacatgacc aaacgcaagt gtcacaagtc ctgtcattaa gaaaacaaat gagtgaaata
    14821 aatgctttct tttcataatc aacctcctaa atttccaata ttttattatt ataggcgaaa
    14881 agtgctgaat cagacaagac tgtaagctcg aaaaaatgaa aaaaatgcga gtttctaaca
    14941 ttttatgtta taaaacataa catgtataat aagataaaaa agtggcgaaa gtatgttcgg
    15001 tgtggtataa ttttttagta aggaatgcct ttgctttcct tttcttttta ttggtcgtaa
    15061 aatgaaaagg aatgaatgaa aaggaggacg aagaatgatt gagagagata cctcccgaca
    15121 ctttgagctt gtctcgaaat accaaccggc tggtgatcag cctgaagcga ttaaccaatt
    15181 agtggatggc gtagtcggcg ggaaaaaagc acaaatctta ttaggtgcga ctggaacagg
    15241 gaaaacatat acgatttcca atcttattga gaaagtgaat aaaccaacac tgattattgc
    15301 ccataacaaa acattggctg gtcagctgta cggggaattc aaggaatttt tccctaacaa
    15361 tgctgttgaa tattttgttt cttattatga ttattatcag cctgaagctt atgtgccttc
    15421 aagcgatacg tatatcgaaa aagattcaag tgtaaatgat gagatcgaca aattacgaca
    15481 ttcggctact agttcattat tagaaagaaa tgatgtgatc gtcattgcat ccgtttcatg
    15541 tatttttgga ttaggctcgc cttttgagta ccaaaaacaa gtagtttcga ttcgacaggg
    15601 agcagaacta gatcgcaatc agttgattcg tgacttagtc agtatccaat tcgaaagaaa
    15661 tgatatagat tttcagcgcg gtcgttttcg agtgcgcggt gatgtcgtgg agatttttcc
    15721 ggcttcaaga gatgaacgtg ccttacgtgt ggagtttttt ggagatgagg tcgaacgtat
    15781 ccgagaagtc aatgcactga caggtgaagt tttaggagaa acggaacacg tagcaatctt
    15841 cccggcgact cactttgtga cgaatgatga acatatggag catgccgtag cgaatatcaa
    15901 agcggaatta gaacagcgtt taactgtctt gcgaaatgaa aacaaacttc tggaagctca
    15961 acgtttagaa cagcgaacca attacgatat tgaaatgatg ttagaaatgg gctacacgtc
    16021 gggaattgaa aattattctc ggcatatgga cggacgtaaa gaaggtgaac cgccttatac
    16081 gctattggat ttctttcctg aagatttttt gatcgtggcg gacgaatcgc acgtaaccat
    16141 gcctcaaatc agaggaatgt ataatggtga ccgagcgaga aaacagatgc tagtagatta
    16201 cggtttccgt ttgccatctg ctttagacaa tcggccactt cggttagaag agtttgaaaa
    16261 acatgtcaat cagatcattt atgtctctgc gacgccagga ccatatgaac atgaacaaac
    16321 agataccgtt atccaacaaa tcatccgtcc gacagggctg cttgacccag tgatcgaagt
    16381 tcgtccaatc atgggacaaa tcgatgatct agtaggcgaa ataaatgaac gagtcgaaaa
    16441 agaccagcgg gtgtttgtaa cgacattgac gaaaaaaatg gcagaagacc tcacagatta
    16501 tttcaaagaa ttagggatca aagtcaaata tttgcatagt gatatcaaaa cgctggaacg
    16561 aacagaaatc attcgagatc ttcgattagg tgaatttgat gtgttagttg gaatcaattt
    16621 gcttcgtgaa ggattagacg tacctgaagt ttcccttgtt gctatcttgg atgcggataa
    16681 agaaggcttt ttacgtagtg aacgttcctt agtccaaacg attggacgag ctgctcggaa
    16741 tgaagaaggt aaagtaatca tgtacgcaga caaagtaaca gattctatgc gtctagcgat
    16801 ggatgaaacg tcaagacgtc gtacgattca gcagaagtac aatgaagaac atgggatcgt
    16861 tccaaaaacg atcattaaag aaatccgaga tttgatttct attacgaaag aatcggaaga
    16921 tgatacaaaa gaagcggtac aagtctcgta cgaagaaatg acgaaggaag aaaaagacac
    16981 gttattgatg aaattagaaa aagaaatgaa agatgcggca aaagctttgg attttgaaac
    17041 agccgcgaat gtgcgagata tgattttaga attaaaagct tcaaagtagg aggacaacat
    17101 ggctaacgat aaaattacga ttcatggtgc acgtgcccat aacttgaaaa atatagatgt
    17161 aacgattcca cgagataaat tcgtggtcgt tacaggtttg tccggttctg gaaaaagttc
    17221 cctagcattt gatacgctgt acgctgaagg gcagcggaga tacgtagaga gcctttctgc
    17281 ttatgctcgt cagtttttag gacaaatgga taagccggac gtagatagca tcgacggatt
    17341 gagtccggcg atttctattg atcagaaaac aacaagtaaa aatcctcggt cgacagtagg
    17401 tactgtgacg gaaatcaatg actatttacg cttgttgttt gcacgtgtag gacatccgat
    17461 ttgtcccaac gatcatatcg agattaccag tcaatcagta gatcaaatgg cagatcaagt
    17521 aatggctttg cctgagcgca caaagatcca agtgttggca ccgatcgtgg taaagaaaaa
    17581 aggacaacat aaaaaaatat tcgaacgaat ccaaaaagag ggatacgtcc gcgttcgagt
    17641 cgatggtgag atctatgatt taagtgaagt gcctgagctg gagaaaaaca aaaaacatga
    17701 tatcgcgatc gtcatcgacc ggatcattgt gaaagaaggg attcgttctc gcctatttga
    17761 ttctttagag gcggccctgc gattagcaga cggctatgct ctggttgacg tgatcggtga
    17821 agaagaaatg ttgtttagcg aacactatgc ctgtccttat tgcggattta ctgttggcga
    17881 actagaacca agactgttct cattcaatgc gccttttgga gcttgtccag actgtgatgg
    17941 tttaggtgtc aaattagaag tcgatcaaga tttagtgatt ccagatagaa cgaagacact
    18001 tagtcaaggt gctatcgttc catggaatcc aatcagctct cagtattatc ctcaaatgtt
    18061 agcgcaggct tgtgaaagtt tcggtatcga tttagataca ccattcgaag aattaccgga
    18121 agagcatcag gagatcatct tgaatgggac agatgatctt ttccatttcc attatgaaaa
    18181 tgattttggt ggcgttcgcg atgtagaaac gactttcgaa ggggtattga agaatatcga
    18241 gcgtcgttat catgatacga acagtgattt cacgcgtgag caaatgcgtc tttatatgac
    18301 agaattaact tgtcagacat gtaaaggtta tcgattgaat ccccaagctc tatctgttca
    18361 aatcaatgga acgaatatcg ggcaaacaaa tgagttgtct attcaaaaag cagtagattt
    18421 cttctcaaac ttaacgttat ctgaacaaga gaaagtaatt gccaaaccga ttttaaaaga
    18481 agtaaatgac agactttcat tcttggaaaa tgtgggacta gactatctaa ctttgagtcg
    18541 cgcttccgga acattatctg ggggagaagc gcagcgaatc agattggcta cacaaattgg
    18601 atcgaatctt tctggagttt tgtatatttt agatgaacca tcgatcggat tgcatcaacg
    18661 cgacaacgat cgactgattg gctcattaaa gaaaatgcgt gatcttggca acaccctcgt
    18721 tgtagtcgaa catgatgaag atacgatgtg ggcagcagat tatttgattg acgtcggacc
    18781 tggggccgga gaacaaggcg gacaaatcgt ggctgcaggc actcctgaag aagtagctaa
    18841 tgatgaaaat tctttgacag ggaaatatct ttcagggaaa aaatcaatcc ctgtaccaaa
    18901 agaacgccgt aaaggtaatg ggaaagcaat caagatcact ggtgcttcag aaaacaatct
    18961 gaaaaatatt agtgttgaat ttccattagg agaatttgta gcagtcacag gtgtgtctgg
    19021 ttctggaaag agtacattgg tcaatagtat cttaaagaaa tcgttagcgc aaaaattaaa
    19081 taagaattct gctaagccag gtaaattcaa gacaatttcc ggctacgaaa gtatcgaaaa
    19141 gatcatcgat atcgatcaaa gcccaatcgg ccggacgccg agaagtaatc cagcgactta
    19201 tacaagtgta tttgatgata tccgtgggtt atttgctcaa acgaacgagg caaaaatgcg
    19261 gggttataag aaagggcgtt ttagtttcaa cgtaaaaggc ggtcgttgtg aagcttgtcg
    19321 cggggatgga attattaaga tcgaaatgca ctttttgcct gatgtctatg ttccttgtga
    19381 agtatgtcat ggtaaacgat ataattctga aacattagaa gtgcattaca aaggaaaaag
    19441 cattgctgat attttggaaa tgacagtaga ggatgctgta gaattcttca agcacattcc
    19501 aaagattcat cgcaaactgc aaacgattgt tgatgttggc ttaggttatg tgacgatggg
    19561 gcaaccagca acgacattgt ccggtggtga ggcacaacgg atgaaacttg ccagtgaatt
    19621 gcacaaaatc tctaatggaa agaatttcta tatactagat gaaccaacga caggacttca
    19681 tagcgatgac atcgcccgct tgttgcatgt attacaaaga ttagtagatg ctggtaacac
    19741 agttttagtg attgaacaca atctagatgt aatcaaaaca gcagattata tcattgattt
    19801 aggaccagaa ggtggagaag gtggaggaac gatccttgcg actggaacac cagaagaaat
    19861 cattaacgta aaagaaagtt atacaggtca ctatttgaaa aaaataatgg tataaagagg
    19921 atagatagct gagatagtta aaaaaacata aaaaaatgaa tttttgcttg ttttattaat
    19981 atcagtgttc tagaatcatt acatggtagt tctttctaca ctgattggta tagataaaaa
    20041 cttcctataa gttcaatccg ttcaaaaaag aattgagcaa tcggaggact ttcctttgat
    20101 tgcttttttc tttatggtat gatattcctt gtgtagttgg aaaagaaaaa caagagatta
    20161 tgagtaagtg agagataatg atgaacagta ttgaaaatga agaatttatc cctatattat
    20221 taggaagcga catgaacgtt tatggtatgg cacgttcttt taatgaagca tacggcaaaa
    20281 tctgccaagc atatgcttcg gatcagttag cccctacccg ctacagtaaa attgtcaatg
    20341 tagaagttat tccaggattt gataaagacc ctgtatttat cgagacgatg cttcgtttgg
    20401 caaaagaaag atattctgat aagagtaaaa aatatctttt gattgcttgt ggtgatggat
    20461 atgcagaatt gatctcccaa cataaacaag agctgtcaga atattttatc tgtccatata
    20521 ttgattattc tttatttgaa aggctgatca ataaagtaag cttttatgaa gtttgtgaag
    20581 aatatgatct tccgtatcct aaaacattga tcgtcagaga agaaatgtta gtaaatggac
    20641 atttggaaca ggaattgcct tttgaattcc cagttgcttt gaaacctgca aacagtgtgg
    20701 agtatctttc tgtccaattt gaaggaagaa aaaaagcttt tattttagag actagagaag
    20761 agttcgattt aattttaggc cggatatacg aagccggtta taaaagtgaa atgattgtac
    20821 aagattttat cccgggtgat gatagtaata tgcgtgtgct aaatgcgtat gtagatgaag
    20881 atcatcaagt tcggatgatg tgccttggtc atccactatt agaagatcct acaccagcat
    20941 cgattggtaa ttacgttgtg atcatgccag attataacga aaaaatctat caaaccatta
    21001 aggcattttt ggaaaaaatc gaatatacag gctttgccaa tttcgatatg aagtatgatc
    21061 ctagagatgg agaatataaa ttatttgaaa tcaatttgag acaaggtcgt agcagtttct
    21121 ttgtgacatt gaacggcttg aatctggctc gttttgtcac agaagatcga gtgttcaaca
    21181 aaccctttgt tgaaacgacc tatggaacga atcaatcaga taaagcaaga ttatggatgg
    21241 gtgtgcccaa aaaaatcttt ttagaatatg ctcgggaaaa tgaagacaaa aaactagctg
    21301 agcaaatgat caaagaaaat cgttacggta ctactgtatt ttatgaaaaa gaccgatcaa
    21361 tcaagcgctg gttgttgatg aaatatatgt tccataacta tattccaaga ttcaaaaagt
    21421 attttcatgt gaaagaaggc tagttcatgg agaatttttt cagtatttta ggcggaatgg
    21481 gcacgatggc gacagaaagt tttgttcgct tgatcaacca ccgaacgaaa gctacaaaag
    21541 atcaagaata tttgaattat gtcttattca atcatgcaac agttcctgat cgtacagctt
    21601 atattttaga tcgatcagaa gaaaatccaa tgccgtttct gctggatgat attgagaaac
    21661 aaaatttatt gcgaccaaac ttcattgtgt tgacttgtaa caccgcacac tacttttttg
    21721 aagagttaca agcggcaacg gatattccta tcttgcatat gccaagagaa gcagcaaatg
    21781 aacttgtccg tcagcatacg acagggagag tagcgattct aggaacagaa ggaagtatga
    21841 aagctggaat ctatgaacgc gaagtcaaaa atcttggttt cgaaacagtg attcctgata
    21901 ctgcgcttca agaaaaaatc aattacctga tctatcatga gatcaaggaa tcggattatt
    21961 tgaatcaaga gctctattac gaaatcttag aggaagcggt agagcgccta aactgtgaaa
    22021 aagtcatcct aggttgcaca gaattatctt tgatgcatga atttgctgaa gataatcatt
    22081 acccagtgat cgatgctcaa tctattttag cggatcgaac gatcgaacgt gcattagctg
    22141 aaagaagcga ggcattggat acagcatcgg aaaagtaaaa aaattggatt tggggcaaat
    22201 atcctaaaag atatttggtc caaatctttt tgtaaaagaa aaagaaaact ggtaatgata
    22261 cgcccgggat gatataattt tattatgcac aatgtgagag gggttcgtaa atatgacaga
    22321 taatttgcaa ttagtcatca taacaggtat gagtggtgca gggaaaacag tagctatcca
    22381 aagttttgaa gatatgggct atttttgtat cgataatatg ccgcctcgat tgattccaaa
    22441 attctgggaa ttgatcaaag aatcaggtaa agtcacaaaa atggctttag gagtggattt
    22501 gcgttctcgt tccttctttg aagaaatcca aaacatgctg atcgaaatcg aaaatacgaa
    22561 cttcatcgac acttctatct tatttttaga tgcttcagac gaagaactag tggctcgcta
    22621 caaagaaaca agacgagcac atccaatggc gatggacggt ttgatcactg aagggatacg
    22681 taaagaacgg gcgatactag acgacttgaa agcccaagct tccgtgatca ttgatacgac
    22741 aacattgaca ccacgacaat tacgtgaaaa aatcaatgag tcattcaaat caaagggaga
    22801 ccaaggattt cggatcgaat ttgtatcatt tggttttaaa tacgggttgc cgatcgattc
    22861 ggatattgtg atggatgtgc gttttttgcc caaccctcat tatatcccgg aactaagacc
    22921 attgaccgga aaagatcagc cagtctatga ttatgtgatg tcctttgatg aaacgcaatc
    22981 attctaccat aaatttttgg atcttctgga aactgtattg cctggataca ttaaagaagg
    23041 aaaaagcagc ttgacagttg caatcggctg tacaggcggt caacaccgtt ctgtggcatt
    23101 gactgaacgt ttggcaaatg ctttagggaa aaactataaa gtcaatgtga cacatcggga
    23161 caaggataaa aggaaagaga cggtgaaccg gtcgtgaaaa tgaaaaccta ccggataaga
    23221 aaaccaaaga tcgtagtggt cggcggtggc actggtctgc cagttatcct gaaaagttta
    23281 cgaaatcaag gagcagatat cacagcagta gtgactgttg cagatgatgg tggaagcagc
    23341 ggtgcaatca gagaatcgat cgctatggct cctcctggtg acttgagaaa tgtcttagtg
    23401 gcgttatcgg atatgccaca attctatgaa gatattttcc aataccgttt caaaaaggaa
    23461 gatcagtttt tagccaatca tacgatcggt aatctgatca ttgccgcagt ttccgagatg
    23521 cggggaagca cttatgaggc gattcaatta ttagcaaaaa tgatgcatgt agatggacat
    23581 gtttatcctt cttcagaaac tcctttgacc ttgcatgctg tttttaaaga cggaacgact
    23641 gcagtaggag aatctaaaat cgcgatcaac cgtaaaacca ttgaccgtgt gtatgtctgc
    23701 aacacaaatg ataaaagtga agccaaagcg gctcgaaaag tcgtttcagc aattatggac
    23761 gccgacatgg tcgttttggg acccggaagt ttattcacca gtatccttcc aaatttagtg
    23821 ataccagaaa tcggcgaagc aatgctcaag acaactgctg aaaccgtcta tatctgtaat
    23881 atcatgaccc aaaaagggga aacggaacat ttcacagatg ccgatcatat acgtgtttta
    23941 cacaagcatt tgaatcagcc ttttatcgat acagtattgg tcaatacgga aaaagtgcct
    24001 gaagattata tggacccaga gatctatgat gagtatctag tacaagtcgc acacgacttc
    24061 aacggattga gaaatgaagg atgtcgagtg atttccaccg actttttaga attgaaagat
    24121 ggtggtgtct tccacgatgg agacaaagta gtagaagaat tgttccgttt agttttcggt
    24181 tcaaaatatt aagcaattta ttgttggaga aaggaggaga ataggatgtc atttgctgca
    24241 gatgtgaaga aagaactaac tggtttggaa gttcatcgag aacatgcgaa agcggaatta
    24301 gctgctttgc tgcgaatgaa cggctcttta ggtattgtga accagcagtt tattttgaac
    24361 gtccaaacag aaaatgctgc aattgccaga cgtatctatt ctcttttgaa agatcattat
    24421 caggtacgaa gtgagctact cgttcgtaaa aaaatgaaat taaaaaagaa caatgtctat
    24481 atcgtccggt tgaagcaagg cacaaaagat gtgttgatgg atcttgatat catggatggt
    24541 atgatgttca atggacacgt ttcggacgag attatgggaa attcgcaaaa aatgcgttct
    24601 tacttacgtg gtgcttttat ggcctcaggt tcagtcaata atccggaaac gagtcgttat
    24661 catttggaaa tattttctat ttatgaacag cataaccaag acatttgcga tatgttaaat
    24721 tattacggtc tacatgctcg aacgcttgaa cggcgcaatg gctatatttc gtatttaaaa
    24781 ggagcagaaa aaattgctga tttcttaaca ttgattggtg caaccaactc aatgctccga
    24841 tttgaagatg ttcgaatcgt acgggatatg agaaattcgg tcaatcgtct agtcaattgt
    24901 gagacagcaa atctgaacaa gacgattgat gcggcttcta aacaaatcga aaacatcgaa
    24961 ttgatcgaag caaaggtcgg tctacatgcc cttcctgaaa aacttcagga aatcgcagaa
    25021 cttcggcttc aacatccaga ggtcagcttg aaagaattag gggaaatgat tccctcaggt
    25081 gcaatatcaa aatcgggaat taatcaccga attcgcaaaa taaatgaatt tgcggaaaaa
    25141 ctgcgtgaag aagcagttta atccaaagaa aaaactgata catgaagcag gagatgcgaa
    25201 tgtatcagtt ttttttaaaa gctatacttg cttttcttcc gtcaaactat aattccaact
    25261 ttactggagt aacataatgt tgaaaggctt ctattgtttt ttaatacaat cgtataaaaa
    25321 gcggggagac aactgaatga agattttagt tttatacata aacttttgct taatatagaa
    25381 gtcctgatat agataggatc aagtatttat ctataactgg agattaatta aaaactggaa
    25441 ggaactgctc gatcaacctt gagaactgtt tttcttactt ctggtcaaga ttctcgtggt
    25501 tggtggataa ggatggttga taagttcatt ggattagcta gtcgaaaaca accaggtgta
    25561 attaatgtag aagttttaac aaggggatgg agtgatttat tcagtgataa tcataagttc
    25621 ataaatagta attgggatgt atggttggta tacgttatac ctgaacttga actatcaaga
    25681 tttggtttag aatttgagaa tcgatgttta taaagggagg gcaaaaaatg tgctttttta
    25741 caacttttac tatcattatg attgcagtac tttttatttt tctagatata gcaaagcgaa
    25801 atacagcatt tttattatat cgggttttac ttcgagcagg tctcataaca tttatatcga
    25861 tcgttggatt ttttctattc acagttattg tatttatttg gagaactaca gcaccaccat
    25921 tgccagagat tacatatgga gaatttccgt ttagtcttga atatgaaata gatgaggaaa
    25981 gaattttgat tgaagatacg gtgattgcag aatttatagg aagttttaga gggaatgtga
    26041 caactcaacc tagacgaagt tggagtataa aacttttaaa taatagtgga gagttgaaag
    26101 catttcatta tgaattctta ataatagaaa gtgaagatgt aacaatcact ttaagtagtg
    26161 gctctgctgg atattttatg aatgatggtg gaagcaagcc acagctcaca gtccgtgatc
    26221 gtattgcagg ttttatgcat ttttctcact atgacttaga agaagctcgt aaaatacttg
    26281 cagaatatgg gatcacatta atcaattggg aatatgcgcc accgataaga aattttttca
    26341 atgattatta ttagtcttat aaaaaacaga atgtaaaatt tatgtgcgcg agtatttagt
    26401 tttccatttt ttgtttgata gatatatagc attgttgaag catgggatag tggtgccaat
    26461 tttatcaatg aggttggtca ggcagttaac ataattggtg atgctataaa tccatttaat
    26521 tggaattgga ggaattaggt gtggaaacag tgagattatg gatattcatg aaaaattttc
    26581 gttcggcttt gagatatgtt attctggaat caaaatcagg ttattatctg attgacacag
    26641 atcactatac tttttgggga ggctaccttt ttccgatttt taattggata atcccccata
    26701 aggttatgaa aattaacttg cctgcagaag aaataaatag attaatactc aacaaagatt
    26761 tacaaaggaa aagagagaaa gaacattcta atgttgcttg gataggtcca gcatttgcag
    26821 tagtgacttc ttcaattgtc ggtcctatgc tagagagtat ttatagtgat ttttctattg
    26881 gaatacgtta tttatttgtt actttaagta tagctgttct tttgtgcata aagggttatg
    26941 ttagcaagaa gaataaagat attttaacac taatcggtgt aaacaattta tctagtacta
    27001 aaattatact gtttcctgaa tctataaaag aaggatcaag gttgttgata atttttataa
    27061 tgcttatact gttttctgtt ttatttgggg tgatgtttat ag
//
LOCUS       DAXLPC010000030        26691 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.030, whole genome shotgun sequence.
ACCESSION   DAXLPC010000030 DAXLPC010000000
VERSION     DAXLPC010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.030"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            148..1599
                     /locus_tag="ACF3UE_001254"
     CDS             148..1599
                     /locus_tag="ACF3UE_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD3634681.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            1948..2580
                     /locus_tag="ACF3UE_001255"
     CDS             1948..2580
                     /locus_tag="ACF3UE_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFD3634682.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            3168..4607
                     /locus_tag="ACF3UE_001256"
     CDS             3168..4607
                     /locus_tag="ACF3UE_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3634683.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4902..5120
                     /locus_tag="ACF3UE_001257"
                     /pseudo
     CDS             4902..5120
                     /locus_tag="ACF3UE_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            5369..5584
                     /locus_tag="ACF3UE_001258"
     CDS             5369..5584
                     /locus_tag="ACF3UE_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634684.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5801..6057)
                     /locus_tag="ACF3UE_001259"
                     /pseudo
     CDS             complement(5801..6057)
                     /locus_tag="ACF3UE_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6244..7155)
                     /locus_tag="ACF3UE_001260"
     CDS             complement(6244..7155)
                     /locus_tag="ACF3UE_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFD3634685.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(7174..8178)
                     /locus_tag="ACF3UE_001261"
     CDS             complement(7174..8178)
                     /locus_tag="ACF3UE_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFD3634686.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(8175..10298)
                     /locus_tag="ACF3UE_001262"
     CDS             complement(8175..10298)
                     /locus_tag="ACF3UE_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFD3634687.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(10303..12750)
                     /locus_tag="ACF3UE_001263"
     CDS             complement(10303..12750)
                     /locus_tag="ACF3UE_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3634688.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12737..13126)
                     /locus_tag="ACF3UE_001264"
     CDS             complement(12737..13126)
                     /locus_tag="ACF3UE_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFD3634689.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(13186..13689)
                     /locus_tag="ACF3UE_001265"
     CDS             complement(13186..13689)
                     /locus_tag="ACF3UE_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFD3634690.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(13702..13926)
                     /locus_tag="ACF3UE_001266"
     CDS             complement(13702..13926)
                     /locus_tag="ACF3UE_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634691.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(14030..15940)
                     /gene="ltrA"
                     /locus_tag="ACF3UE_001267"
     CDS             complement(14030..15940)
                     /gene="ltrA"
                     /locus_tag="ACF3UE_001267"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFD3634692.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(16686..16823)
                     /locus_tag="ACF3UE_001268"
     CDS             complement(16686..16823)
                     /locus_tag="ACF3UE_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFD3634693.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(16820..18004)
                     /gene="mobT"
                     /locus_tag="ACF3UE_001269"
     CDS             complement(16820..18004)
                     /gene="mobT"
                     /locus_tag="ACF3UE_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFD3634694.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(18263..18553)
                     /locus_tag="ACF3UE_001270"
     CDS             complement(18263..18553)
                     /locus_tag="ACF3UE_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634695.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(18543..19685)
                     /gene="dcm"
                     /locus_tag="ACF3UE_001271"
                     /pseudo
     CDS             complement(18543..19685)
                     /gene="dcm"
                     /locus_tag="ACF3UE_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(19761..19925)
                     /locus_tag="ACF3UE_001272"
     CDS             complement(19761..19925)
                     /locus_tag="ACF3UE_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634696.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            complement(19918..20592)
                     /locus_tag="ACF3UE_001273"
     CDS             complement(19918..20592)
                     /locus_tag="ACF3UE_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFD3634697.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            complement(20670..22010)
                     /locus_tag="ACF3UE_001274"
     CDS             complement(20670..22010)
                     /locus_tag="ACF3UE_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFD3634698.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            complement(22093..22428)
                     /locus_tag="ACF3UE_001275"
     CDS             complement(22093..22428)
                     /locus_tag="ACF3UE_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HFD3634699.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(22438..22812)
                     /locus_tag="ACF3UE_001276"
     CDS             complement(22438..22812)
                     /locus_tag="ACF3UE_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFD3634700.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(22825..23139)
                     /locus_tag="ACF3UE_001277"
     CDS             complement(22825..23139)
                     /locus_tag="ACF3UE_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFD3634701.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(23252..26479)
                     /gene="fss3"
                     /locus_tag="ACF3UE_001278"
     CDS             complement(23252..26479)
                     /gene="fss3"
                     /locus_tag="ACF3UE_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFD3634702.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
BASE COUNT         7763 a         5550 c         4646 g         8732 t
ORIGIN      
        1 ttaaaggcag taacaggatt aaacattgaa acataatcgt tactaaatga aatcaagaaa
       61 tatactgtat tactcaattc attgaaaata tttatcataa tttttaatag aaaacactat
      121 taaagagaaa aaagagaggt aaatcaaatg aaaaaatctt taaaacttgc atcagcagtt
      181 atattaatgt cccaactcct tatagcaaca cctttccatg tgttggcaag cgaaaattca
      241 acatacaaaa ttgcaaaaga aagaaccgag acgactgaaa tgagtaattc cgatgtaaca
      301 gcagagagta gtgaactttt gacaacttca tcaagtgaaa gtagtacgac ttcaaatgcc
      361 gagtcttcaa caacttcatc aagtgaaagt agtacgactt caaatgccga gtcttcaaca
      421 acttcatcaa gtgaaagtag tacgacttca aatgccgagt cttcaacaac ttcgtcaagt
      481 gaaagtagta cgatttcaag taccgaatct tcaacaactt caagtagtac aagtgaaata
      541 acttcttcga aagtgacaaa accaaaccat atagaatctt caaaaaagga agcgccaaaa
      601 acggaaggac aaacaaaaac tttttcgaca ccacagcaaa tagaatcaac agaatctttc
      661 caatcacaac caatactatc tggtaatgaa gaaattcatt ttgacaaaaa tgaatctgta
      721 gaaaatttta ttatgaaaat tggtgagtct gcgagaaaaa ttggtcagaa atatgattta
      781 tatgcttctg ttatgattgc acaagcgatc ttagaatctg ccagtggtca aagccagtta
      841 gctcaggcac cgaattacaa tttatttggg ataaaaggaa cttataatgg aaactttgtc
      901 attatggtaa caaacgaaga tttgggtaat ggaacgcttt atacgaccca atcaaaattt
      961 agagtgtatg aaaactatga ggaaagcttt gaagattatg ccaaattatt aactaaggga
     1021 attagtggaa ataaagattt ttatgcagga gcattaaaag ctaatagtaa aacatatcga
     1081 gaagcaacta aattccttac aggacggtat gcaacagata cacaatacta tttgaagcta
     1141 aatgaattaa ttaaaaccta cgatttaacc aactatgata aagaagttaa aggtccacaa
     1201 atgagtaaga ctggatacca agtgcctatt cataattatt caataaccag tttgtttgga
     1261 aatcgtggaa atgaatttca ccgaggactt gatatggcag ctacacaggg tgagccgatt
     1321 catgcagtta aagctggtaa ggttgttaaa gcagagtttc actactcttg gggaaattac
     1381 gtggtgatac aacacgaaga tggatcaacc gcgttatatg ctcaccagca acaataccta
     1441 gtaaaaactg gagataatgt tttgcaagga caaataattg gctatgtagg aagtactggg
     1501 aatagtactg gcccacacct tcatttggaa atttgcaaag atagtagtct ttctcagagc
     1561 atgttagttg atccgaaaac cttattattc ggagactaaa aaaggtaatc aatctgacaa
     1621 agtaacaaga aaatggttgg attcttagac ctttgatcag gatattgaga ctggaattga
     1681 tatctcgatt acgatgggtt tgacaaataa aacaagtcca ttatcgaata tcgagtgtat
     1741 tattgccgtc tttatgctca tattttgagc aggtttcact agatgaaaac aatttatcta
     1801 tcttgaggat ttcgtgtacg tatcgttcag tcttgtattg taaattagtc ataaaatcag
     1861 actaagaaaa attggaaata tttttttctg atttattaaa agttaattga aattatatgg
     1921 tacttctttc ttgggagggt aggtgcagtg aaggaaagat atggtcacct tactgttgtt
     1981 gaggagatta ctcataatgg atataaaaaa tatcgttgcc tatgtgactg tgggaatgaa
     2041 acgattgtat atcgatcaaa cttactaaca ggtagaacca aaagttgtgg atgtggaaat
     2101 tataaaaata ggcataaata taaaaatttg acaaataaaa cttttggtaa gttagttgca
     2161 atcaagccaa ctaaactgcg aagtgaagga actgttgttt gggaatgtca atgtctgtgt
     2221 gggagaaaaa agttagtatc ggcaaagcga cttctaaaag gtgatgtaaa aagctgtgga
     2281 tgtttgaaat caaaaaagca tcacattgaa aataaaaaat tcggattact tactgcaaag
     2341 tatcctttgg acaataactg ttcatggaaa acaaaatggg tttgtcattg tgagtgtggc
     2401 agtatgtgtg agataagtta tagtaactta ttttttggac atactcaaag ttgtggatgt
     2461 ttaaaaaggc aagaaacaag gacatgtgtt gaagggacag taatagagtg tctaacgtca
     2521 aaattaccga aaaataatac aagtggtgtt aagggagttt atcgttctaa agagaaatag
     2581 attgcgtata taactttaaa aaaaaagagg tactatttag gatcgtatga ttctattaag
     2641 agtgcagctc aagctagaaa agatgctgaa aataaattgt ttcaaccttt gattgacaaa
     2701 tatcgaggta atcattaatt attgtggata ataattaaca gtgatatata aacatctata
     2761 atatattatt catactattg atatttagta taatcctatg gaattgaata tcatagcaat
     2821 gtatttgaaa agcaaattgg aaaacaaata ggtgcaacac cataaatatg aaaaaattgg
     2881 gaaaaagtag aatggaaatt tgcttacgtc tcacgagata gctcacacta ttaatctgaa
     2941 gaacaatgaa gtcgactttt agaaattgct agaagaaagt aaagcgaatt atcactagtt
     3001 actatagagt aagttcaaat aaagcatctc caacttacat ggttacatga ggatatcaaa
     3061 tcgaaattac tcaagcttcc tatggctaga gtcgcgagaa gttgttgggc agtagacata
     3121 ggttatattg ttcttagcta cacgatcatt agaaaggaaa tcctattatg tatagttatc
     3181 aagaagatgc aaaagtccaa aaaaatcgct ggtggatttt gattgctata tctatgttta
     3241 ccttcatgtc cacattggat ggcagtattg tcaatattgc actacctacc atctcagatg
     3301 atatgggcat accaatgaat caagcggaat gggtagtgtc cgtttatctg atgattgtct
     3361 gttcttgttt gttgctgttt ggtaaaattg gcgatagccg tgggaaaatc aaagtatttc
     3421 ggattggtac gctgatcttt gtcttgggat cgctgttgtg tgggttcaat cattcgctag
     3481 gtattttatt gttcgcacgg gtggtacaag ccattggtgc tagtatgact atggctacaa
     3541 atgccggaat catcacggaa gtctttccca tacatgaacg tggtcgggca ttgggagcaa
     3601 taggtgcgtt tgtttcatta ggctcgattg ctggaccagg tcttggcggc ttgattttgt
     3661 cccaattttc ttgggcgtac attttttgga tcaatgtacc ggtgggaatc gtaacgatgt
     3721 tgattgctga aaaattctta ccaaaagata tcaccatgag cggccataca atcgatggag
     3781 ggggctttgc tgccattgcg gctacgatta tcagcttttt tggagcaatc tttttggggc
     3841 aagaaagtgg ctttttccat ccagtccccc ttgtactgtt cgtaatttca gtgattgcct
     3901 ttgtcagctt tttaaaagtt gaaaagaaag cagcctctcc attgatttct ttcggtattt
     3961 ttaagaacaa gatttttacc atgagcttga ttacagcctt gttgattttt tcttccaact
     4021 tctttgtcaa tgtagtgatt cctttttatc tgcaaaatgc tcgcgggttg agtcctagct
     4081 atgctgggct gttgatgatg gtctttcctt tgatgatggt cgtcggggcg cctttaagcg
     4141 gctacctgac cgaccgggtt ggcccggaga ttttggtatt agtaggcttg ggcttattgt
     4201 cggtaaccca ggtcatgtat atgtttttgt cagtggactc tcctttgtgg ctatacattg
     4261 tcgctactgc catcatgggt gccggcaatg ccttgttcca gtcccccaat aatacgatgg
     4321 ttatgagctc ggtcactatc gaaaacttgg gactggcagg ctcgatgaat tcctttgccc
     4381 gaaatttggg gatggtcagc gggatttcgc tttctacgac ggtcttatat caagcgatgt
     4441 ctgctaagat gggccagcaa gtaactaact atatcgcaaa tcggccggat gtctttttat
     4501 atggaatgaa gattaccttt ttaggcagct ttgttttgtg ttttgttgcc tttttcctga
     4561 ctatctggcg tatcaaaaaa caaggaggta ttcagaaaaa tgtctgaaaa aaccactgtt
     4621 gaagaatttt tggaggcctg cgtatgggtg agtgggattt ccatggatga tggaagatga
     4681 agtgaacttc taaaagccga aaaactcaag tattatcttc aaaatactag tgctcaatga
     4741 gatgcttgat ttgatcacaa gaagactgcg aaagccgctg gcaaccgcaa gctaggtatc
     4801 ccaccgatgg actacgtttt agaggctact ggttatgaat acggagccaa cgctctcatc
     4861 tgcataagaa tacatcaccc agattatgta aagattttcg atacttctgt caaaaaatca
     4921 ttaagataga taaatgattt ccgtctagtc aaattggttc agaatgtaga cacacagatg
     4981 gtaagaagtc actcacaatt cgagaatgga cttgtcctat ttgccgtata catcataatc
     5041 gaaacgtcaa cgatagtatc aatattttga ccaagggcta tgaatacaag cattgcctta
     5101 gaaaacatca agaaccttag gaacaacggg gatagcttgg ttaataagag ataccgctgt
     5161 ttaggcttgc aagtatactc ttttatcaag aattccgtgg ctttagtcat gagaggctta
     5221 atactatgaa aattttcttt agcatttttg atttaggttc cttttctaat tataataaga
     5281 tgaccactac agtaacctac tgaaatatat aaacagccac tgtagtacca ttttcaaagt
     5341 agtctatgag aggagaatct tcattcttat gaacgctgga attgcggata tgaatttaat
     5401 aaaaaaaacc cttaatgatt ttacttccaa ttcaatatca aaaggtactg gtatcaattt
     5461 aagcacaata aaaaagctga aaagtggtga aagatcagtg gaaaagctga atcttttaga
     5521 tgctataaaa ataacggaat ttgctatgaa aaatggaaaa gctgagattg aaatatggag
     5581 ataattatcg tctagtgaat tacttgccac ttagctgaat ttaacgatcc ttggtgcttg
     5641 aagggggaga ttcttgggaa tagagcatac ttgcaagcct atgtctttac taacaacgat
     5701 atctcttatt aaccaagcta tccccgtagt tctaaggctt ttacttttat ctaagcaata
     5761 atcgtattca aaggaaattt ttgaccctta gaaagtctca ttttatcaga cgtgagctta
     5821 ggcattgctg aattttgtta attcggtttt aggttgtgct ttgagcataa tatgaaagta
     5881 ttctttatca cgatttcatt catctaaggt aatgtgatgt gattctgaaa ttctttcaaa
     5941 ggcagttttt gcataagctg acattacatc atcaatgaca tgtttacaat gtttcactac
     6001 taaaataagg gggtaaccaa gaagaaaaac tgaatgatta tttgtatcta attccatggt
     6061 atatcaacca tttcctatat agactgatta tgacatggat taaaataaaa aggcactatg
     6121 tcttaattgt cggttttcga gttaccgaat ggcattcatc acccacctat agaggatggg
     6181 cgacttctgc ctgaaataag ttacactact tataacttct aataaaatta gattgagtca
     6241 ttattattta acatcaacga ttttccagtt tccatttttt tgtaatacta atttgtactg
     6301 aaagtagcta gtggtttttg atacattatc aaggtatttt atctttgtac tcactagaaa
     6361 attttttccg ttttgtagat aaactggatt ctctaactcc gaaaacttta agtcaatatt
     6421 gattggtcgc atcgcaccat tttcaacata atactccaat tctttttcag aagctgatgg
     6481 ataaagttta aaaaatgttt ctaaaaaatc ggtgatttct tccgttgttt tggcatcaat
     6541 ttctgaatcg ttttctactt gttttgcttc atattttgcc ttgtctggct ttccaatcat
     6601 tgttggcaaa ctagttacta aatgattcct gttttcatct tcaaagattg tcactcgata
     6661 tgcagaagaa attgattgcg tcttttttcc ctctgtaata tgttgctcca ctaaaaatga
     6721 aacgacaaat tcttccgagt gtttttcaac atctagaatt tttacagatt gaacttcgga
     6781 actcgtggga atatctgctc gaaccatatc ttggattaaa gcgagaccgt tttctgtaag
     6841 gtactgttcg agattactca ttctcttttc aattgcttct ttgttatttt tccatgaaaa
     6901 atattctttc gcaaaatcct ctgtaaaact ttcaacgcca gaagtattca ctaccttctc
     6961 ttttataacc actttttcat gagttgtatg ttgatcaatg gcggtgaaat ttttataaac
     7021 gccaaaagca agactacaag acaataaaag ccaaagggca agcaccattt ttcgatgctt
     7081 acccacggat acaactcgtt cttttttctt ttttgggctc ttttcctttt gattccgttc
     7141 aatttttatc ttcattcttt ttcctctttt ctcttatttg tatcggccag ctccgataag
     7201 atgctgccgc caatagtttt ccgttagatt cgtccacccc actggatctc ctgcatgaaa
     7261 catgcgattc tcccctgcgt aaatgcccac atgggtcaca taagtaccgg catcataggt
     7321 tgaatgaaag aaaactaaat cacctggttt ggcatctttt agatcaatat gagtcatggc
     7381 atcatattga tcctgagcca cccgaggaag tttcaggtca actttggcat aacaccattg
     7441 ggtcaagcca ctacaatcaa accccgtttc tggacttgag ccaccaaaca cataggccgt
     7501 tccttcatac ttaaatgcct catcaaaaat ttcttggact attttgtcat caaactgagt
     7561 tgtagttagg tattgcttca ctaataaaca gtaaaacata ttgccataat tataccgcca
     7621 cccaccattt tccttaatcg cgattgggtt ggggtaatcg actttttgac cacctgattt
     7681 ttcctttgaa aaagattcag ctaaagcaaa actatgcttc ttcccgtttt tcccgacatg
     7741 atctagatac ccgccaccat agttataggc ctgaataata ctatcttgat cacaccctag
     7801 ttctttggaa cgcttaacca aagacgcaaa atagagacag ccttgtttga tggatgcctc
     7861 ggtacttaat gaattaggtg gtaatccggc tgactcagaa ctttgcataa cgtcttccat
     7921 tgtgccacca gattccactt gaataatcgc caaaagaatt ggaatatact ctgttatatc
     7981 cgattctttg gcatactttt ccaccattgc acggtgtttc aatacttctt ctgagacact
     8041 agttccgcca ggagaagtgc cagaactacc atttccctca ctgtcttcac caaacaacaa
     8101 acccacacac atcaaaatac ccataaaaga gatggtcaga aaagttaatg aaataacacc
     8161 cactttcttc aagttcattt tttctcacct gaccttgatt ttggacgatg gttcattctt
     8221 ttttgtactt tttgattggt ctgctttggc agagtggacc tctgtttcac ttgttggaaa
     8281 gaatttttct tacttgctga ttggcttttc ccttttgaaa tgatttcttg actagttagt
     8341 tttcgtttga tttcgggatt cagatttgct ctcacaatcc gctttggtgc ttcttttttc
     8401 agcatcatat ctttctgagg ttgagctgct ttatctattg gaatattcgc ccttcttttt
     8461 ccctgacgat ttgttgcttc actcagtatc ttgcgttttt cgtccatttt cgcatttctt
     8521 cgttgtcgtt gtttttctcg caaatccact cgatccgctt tttcttggaa cagtccgcgc
     8581 ttgaattctt ctggtgcttt tttcgacttt tcgattcctt tatggagatt gtatttcaaa
     8641 ttcgttggcg tattccttac ctgatccttt acttgtttag tcttatcttt caccaaagct
     8701 tgggtatcca aaactttgcc gatttttctc ccagccaaat tcattcggga ttgtttctta
     8761 ttatttgaaa ctggattctc cttagttaag tcagatagta tttcgtgatc gttcggtaat
     8821 cgtgaattct ttcgtagaga agaaccggat ggcttaaatt tggattttga ttgttccttt
     8881 gccaacttat ttccgactgc tgcaccacca ccaaaagcca aagctcgtcc cacatttcga
     8941 ttgagttgcc gcaattttcg attcattaac atttgcggtt ttcgcatgac gcgtcttccc
     9001 attgactggc tatcattact ctggaggttg aacatactca taatgtcgcc caatttgaaa
     9061 tagataccgg caaaggtcac aatttgcaga aaagcaacca tgaaaaatgg ataggttgcc
     9121 gaaatattga aaaacatcgt ggagatgcta aatgcagtcg taatcaccaa agtaacaccc
     9181 gctcgcatca taatcgtatt gaataaacga ataatcgcct tctttcctaa actttcataa
     9241 gtcggcaaca tggacaataa gaaactaatt ggcagaaaca tcgcaaagat aatgaagaga
     9301 atttgcgaga acaacataat ccctgttaga agaaaaacaa agaaggaaat gccaatattg
     9361 aacaatacca aaaagaccac ggtccctaaa cggttcatgg tcttggtaat actgagattc
     9421 gcattgtcat tgtcttcaat ctctgccttg accgcttctt cccgatcttt gcctttgttt
     9481 tcatctggac tcacagatag aatcttgttg acccggtctt caccaatttc ttctatgttg
     9541 gaatcatcaa attgcagtag taaccaaggt tgttggactt gaatcgaaaa caaactatcc
     9601 cgaatcaaat ccacactatc ttttccttgg ctttctgaat tgggtacaac gatctcggtt
     9661 ccaagggtaa gggccgcttc actaacatct gagctaaagt cattgatttt tgtgatatag
     9721 gtaggcgcat aagcaatgaa cgaacccgat agtagaaaaa tcatcacaaa attaatcacg
     9781 gctcgaactg ctttcgtggt ttctcgtttt aataatccgg tatacgccac atacaccccc
     9841 agagctaaaa tcatcaataa tagaaaccca aaataaaatc cggaggtctg gagtccattt
     9901 tcagtaatac cagccaatgt ttggatattc tttccaatac tttcagccgt atccgaaatg
     9961 aaatctaatt tgtaagcctc ttgaaccaca taacccgtgg cgttcgacaa atacaaactc
    10021 accgtccaaa tgaaattagt aatggcataa agaccataca tcacgctttt ccctaagcca
    10081 tcaccccaat tccaaggcaa ccaatcccaa gagctatcca caaagaaatc tagttgatag
    10141 ttgttcagtg aatatttgga atatagattt cctgcttcaa ctgtatcatc aactagccct
    10201 gtcgcctcgg ctaccgtacc aactaaactc aatagaacta tcagagtgag tatgctaata
    10261 aaaacgattc ccacaatccg aaaaagtttc tttttcatcc cctcactcca ttctctcttg
    10321 aacaggtgga cgggtatcaa aggcatggaa gagttcttca aagactggat gtacctgaac
    10381 cacgcctacc cgaccataca aatcctgcat caagcattgg ccattttcca aatctcgtag
    10441 gcgtttttga ttgctttcat cttctcgatc caagccaaag aattccaagg ttttcttgat
    10501 ttcatgaata tcggtactgc gaaacgcaaa cttcaacccg atattattct tcaagcgttc
    10561 atccagtaaa tcatcactat tttgcgtgac aaagtaaacc ccggcattca tagcccgccc
    10621 agcacgaacg agcttattcg ataatgtttt cccttgcgct acttgaagaa aactccacgc
    10681 ctcatctaag tctacaattt tgaagatttc tcgattacta tggataaagt ccaaggcaaa
    10741 agtggaaatg acgattagca tggaaacact aagcaattcc atggtggtat attcttcaaa
    10801 agtggtttct gcatctggta aaaccaaatc cgctacttga atgatattta actgcctatc
    10861 taaactaatc gactgggtaa tcgaaccatc tgagaaaagc aaatgggcaa aatcataatc
    10921 ggtaaaggac tcgatgtgat ccgcgatatt ttccgcaact ggtgagcctt cttttcgaag
    10981 ctcattaatt acttgtaata atccccgttg attgctttgg gtaaccgtcc gaatggcctt
    11041 acgcaacact ggaaacttct ccccatctcg actagaaatt cctgttaaaa aggtcagaat
    11101 atcaattgct agactttcag aatccttctt tttctccata atcacataag gatcaagtaa
    11161 tccttgattt tttggcttac tagttaagtt gagaatattg atttcatccg caatttctgg
    11221 caaggtttct ttccagccac cccgttcccc ttttggatcg acaatcacag cttgtccacc
    11281 aaaaaggacg gcgtaataaa ctaagagatt gttactaaag gactttccgc caccgagtga
    11341 accgaggaat gccgctgcta gcgcattggt aactgaatcc ttgacccctt gtgaggccaa
    11401 tgccggtttc aggtaaacat tgcgccccgt atctacgtta taaccaaagt aaatgccttc
    11461 caactcccct aacatctgag tggcgccaaa accaagtccg gcgagaaaat cagacgtaac
    11521 atactggata taatcattca tgtatcgctt actagaaggt aagaattctt catgtagccc
    11581 catcatatcg ccaaaaggcc ggactagttt tacattggta tcatcataaa aatctagcac
    11641 ttcatcacac cggcgcttta gttcatctac tgattcggca cttactcgaa ccacatagct
    11701 cagtttgtac atggattctt tggactgatc caaggtagtt tccaattcat ctacggaatc
    11761 caatgcatct aagacattgg aatttgtttc attgtcagat tgataggcat ggttgtccaa
    11821 gtcttttaat tcctttttct tattgcgaac ggtagcaagt gcctttttgt tcgtcacaat
    11881 ctccacattc atactagtgt caattgggaa tgtaaattgt tgttgctggt aatagaaaag
    11941 ttctgaggag ggaaactcca tttcccccac aattgtatta attgttaagt acgctacata
    12001 tgattcatga ttctcatgtt ccatgcataa gtaccggggc ttttcttcaa tcaaacaacg
    12061 actgggacgt aataagtcgt aacgtttcac caaagtttcc gacttcagct ttttctttgg
    12121 tagctgaaat tcatattctt caaatggtgt acccttttcg ccatagatat gttcaatcaa
    12181 atacatcaga tcactcggtg tgactcgtct gactttaaat cttcgagcca atttactttc
    12241 cattagtttt tcaagcttgg tatatcggcg aatttcttca ttggataagg aaacaaaatc
    12301 gcccatcaaa tgatgattca ctccatagac aaattcttga aagccggaga agaaagattt
    12361 cttgagattc tttagattga cctcttcatc tgtcgcaatc agtttgaagc caataaaaaa
    12421 gcgataatca atctgactat cgccaatcat ggatactaat gcctctgtct gtaaatcaat
    12481 tcgttgtttc gctacttctg ttaatcgccc ggtaatttcc ttttttgatc gttcttgcgt
    12541 ggcacgaata ctactttctg tggcaatttg taaggcatga atcttgcctt cacgattttg
    12601 cgcaatcaat tgacgaaagt tatcgtggac ttgatatttc tgttcaggtg acaaaaagga
    12661 gtaattgtaa ggtattaact catagtaggc aaaacattct ccctcttgat taaagacaag
    12721 attattttca atatacttaa tcgggtacat agttcacact ccttaccaga gtaatgggtt
    12781 cgtcccatcg tttcttctgt tctttgactt tctttcctgc gaaagtgacc ttaaatcgta
    12841 agtgatagct aataaaagat cgtaaaaatc ccaatggttt cttaccgtca aacgtttttt
    12901 gcgacatgaa ccaagtaact gccaccggta tacctaagta ttttaaaaag gccccctcta
    12961 tcatagatag tggaggcaca tgggcaaata cgatgacaaa cagcaaggat aaaacaaacc
    13021 aagccatctg gttaaaagtc acaggaaaag gcagttgaaa gtcattaatt gcataaatga
    13081 ccttttcaac tgcccaaata ctggtgtagc tttttatttt cttcatcaaa tcattccttt
    13141 aaaaagaagg atagtttaga aatcaactac ccttcaataa ttttgttaat atggatactc
    13201 aaaaacacct cgactcgtta ccaaataatt gcctccaatc tccaagtctc taccacacgc
    13261 atcaaaatca atatacgtct tcaagtgttc tggtacttct ccaaaatcac cagcttctac
    13321 aatcaagaaa tatgctacat cactcatatc atcgcaatct ggataataga taatatcatc
    13381 cacatgctct accatctcct caaaagaatt gaagaaagca tgttgaatct cagaagcaac
    13441 ttcaccaact ggcgttcctt caagttcctc cgctaagcca cacaaccgat taatttcctc
    13501 aattggcgta tactcatcaa tctcaaaggg aagttcataa tcatgaattg catattcctc
    13561 gtattcgtca tttaacccaa ttcgttcttt cacttcatca aaatcgacag gtggggtaaa
    13621 ccacgccccc accaattcac cttcgttata tttcccgagg ttcgcaatat aaacacgcat
    13681 ctgttccatc gtgcttcccc cttacgcacc gacaattcgg ttaaacaaac tgagtaagac
    13741 atccttcacc ccagaagcat taaagaccaa tccgaccgca atcaaagcaa tcaccaaaaa
    13801 gccaatcagt ttggaaaact cccgcttaaa tcctaaaaac aaaccaatga ccacaattgc
    13861 cagtaagact aaggattggg cattggttaa aaaccattga tatatggata ggtaagttcc
    13921 tgatattata aatatctcaa acttttcccc ccattcacac ggagcgtgcg actttcaccg
    13981 cactccgcgt tccatcgtgt ttatattgaa aagtatttat gtagtagacc tatatcaagt
    14041 ttaattcttg attgccagct aatactctat atttatttag tcttatgagc tggactttat
    14101 ttagcttcaa tagagctata tatttttgta ttgtttcttc tgttttagcg tgtattagac
    14161 ggtgtaccgc ctcttttacc aaaataagat ttttataatc gtcatttcca ccagctccag
    14221 ttggtacaat atgatgacaa tgtatttcat tagcttgttg aaattcttcc agagttatag
    14281 cacattttcc atgttgagca gaaaatagcg aaattcgatt gtctgcgtat tctattgtgc
    14341 gattttccaa agataatttc attaactggt acatcagtaa tttatcaaca cttagattgg
    14401 tgtggataaa ttttcttccc tctagagtgt agcaattcgc taaatacacc tttgccattg
    14461 gttttctgtg ttggatatat ccaacaggga aaataggttc gccctcgcca gcaacatacc
    14521 gaagcatttt agatttacca tatcttgttg cctcctttgt cgtaagttgt ctgcctgttt
    14581 ttctcaatct gccccttttg tttgtaccta atctgttagt gaagatagcc attacagctc
    14641 tattcagttt catacaatcc agatttacat tcgttgcaat ctgataataa ttttgcatac
    14701 ctaataccat tgaattataa agtcttgttt cttctaattc cgttttccct tttgagggag
    14761 aagcaatttt ctttgcctgt gataccagct tgtctttttg gtttttgaat tgtttatcac
    14821 ttatatgtga tttaacaact aacttctttc ttctcggtat cattttaatc ttgaaaccaa
    14881 gaaagtcgga gtatcttttt ctaacattta caattcttgt tttttcttgt gatacttcca
    14941 attttaatcg ttgttcaatc cattgagtga ttgctatttt ggctttttca gcactttcct
    15001 tgtagcggca gaaaactcta aaatcatctg cataacgaac catatacatt tcctttaact
    15061 ttgttttctt catttctttg taagcgttgc ttttacatgg gctaccgctt ttattgatat
    15121 gaaccacata gttttttgta acaggatttt cctgccattg gctttctacc caatggtcta
    15181 actcattaag aacaatgttt gctagtagtg gggatattat tcccccttgc ggagttcctt
    15241 tctctggata tgttattgta ccgttagtca ttttgattgg agcttttaat atccttttta
    15301 aaatgaatat caagtgcttg tcccgtattc ccatagccca tatctgtttt atcagcttgg
    15361 aatggttcac gttgtcaaag aaacccttaa tatcaaattc aatcacataa tgtagctggc
    15421 tgatttgtag gcggttatag gttgctttta ttgcattttc aactgaccta ttaggtctaa
    15481 aaccatagct gttttcacta aatttagctt cgcagattgg ttctaatact tgttttatac
    15541 attgttgtat aagcctgtcc cacatacaag gaatacctag aggtctggtt ttaccatttg
    15601 gttttggtat ttcttttcgc ctcactggct taggtcgata cccatgtgga ctgcctgcaa
    15661 caatgtatct tacttttttg acaactgttt ctgctggcaa tttgccaata tctttaatta
    15721 ttgtaccgtc tgttcctgct gttttactgc ctgcatttgc tttgatattt cgatatgcca
    15781 gtaatatatt ttctctcgat aggataatat ccataagatg agtgaaaata tctccattct
    15841 tacttttggc atataaatca tcaaaggtgt tttgcatttc gtaatattca gcgtgtctta
    15901 aatcttctac acacaatgtt tcatttttat ttttaggcat aaggcttcac tcctttactt
    15961 gaaattgagt gagctttttt atcttactcg taatccttat tgaaacaaca taatactttt
    16021 ctaatatata cacgacttga gggcattcct ccattctcat tacaagaatt tcttaggttc
    16081 gccctctgct tttcagcatt agttcaactg cttattgttc ttcgtcagtt tattctcttg
    16141 atgagaaccc aatacctttc ctcgttccga taatcttatc tatacatata tatccttagg
    16201 tcactagcta taagcctgct ggcttgatac cgcctgtaac gttatatggc atttcataac
    16261 ctatattctt actttgccac accagctacg atttctcgta cctttgcatt tctacaaagt
    16321 tcaaatttag acccgtacat tcgctgtttc gtcagttcct tatagaacat tctaaccata
    16381 gatattttat agacccccga cctgttggat acgctaccca cctctggata gttttcgata
    16441 gaagatatat gttcatcaac tattacggta tctttcagcc gtctttaccg agcttcaaac
    16501 attctgagtt tcctcataca atgcttgtcg gaggctcagg gcaggcgttt cagagcgtta
    16561 cttcatcatt ccacctgtca gattatcagt tctcctaata accaaacttt ttcgttcttt
    16621 tattagtgcc ttagcttttc actaaggaac gagtcgcaca taaattttgt ccgaaattca
    16681 tcttgtcact ttcctttctt ttccattgct cgatccgctg ctgcacttgc attcatcaag
    16741 cacatcacag taacaccaag catactgcca ccaaatacca aaaaaatatc ttttacaatt
    16801 cccatgacga ttcctctttt catataatca aattttcaat tgccatactt tgttgctcca
    16861 aaatcttttt atgtcggtct gataagcgtg cattctgtac catatcctgg atataggttg
    16921 tccgattcaa tcgatccaac tccttagcca ttttccacgt aggggcgact tgtcggccta
    16981 gccaattcaa ggttcgttca atggtatacg gttttggctc ggaagttaat tgaatctctt
    17041 tccgattccg tccaataaaa cgcccccatt gttcattcaa gggccagttg gttcgccttt
    17101 taccttctac tttatccgca aatcgcaagt aacgattgat aatggaaaac gtggtgctct
    17161 caatgctacg accttttaac aaatcttgaa tcgcatgaaa agcacggtca tttttcagtc
    17221 gaatctcaaa acgatttttc gtctcagttt ggtctaatgg aatccctaac ttgatatatt
    17281 gttcatagtc tttttcatac aaacagaaat aaacctcact cttgagactg ccgatatata
    17341 aggtattgcc catgccgtcc ttttcatcag cctttaaaag ttccccggaa cgataacttt
    17401 taaaggtacg aaacaaggag atacattctt ccttctgaca ttttttcgtt agctcaggta
    17461 tatccaatag ccccactcga tcattgattg ccaagtccaa gcgtttcatc acgccaccgg
    17521 cctttagaca atcctcgaaa aagtcgtacc agctacgctt ttgagcgagt aaaaaagttt
    17581 caaattgtcg gcaacctcgc ccctttaatt ctaaaagcac acctttatct tcttcatgag
    17641 acaacatcac cacaatatca cccatgacat actgttcttg ataggagtaa aaggcataat
    17701 cttcatggag catatactca aatttcaaat ggagaatttc ttgaataatt tttcgtgcat
    17761 ccgttgtggg aaagcgaatc cttacatagt caaacagtaa cgtcaaaggc aaatcgggat
    17821 taaagctttc cagttggtca aaaattttcc tcatggtttt tatagatgcg gttacgccac
    17881 cattttctat ctgatttaag tacggccgac taagtccaca agccgtagcc aatttatttt
    17941 gtgaaacgcc gtattcgttg cgtcggtctt ttaatagccg ataatctaaa ttccgttgtg
    18001 ccaagttctc acctccaaat tcaaggtgtt aactttttca aatgagttaa cacctataca
    18061 aattacttac tatctttgat acaacaagca ttcttaatgg ttgcttactt attttttgtg
    18121 tttttgtacc cccctgttag atacgggggt gagacatcat ggtcggctaa cgccgtccat
    18181 gaacaggcac agcaccacgg aggatttctg cttcgcgaat cctccgcggt cagcgcctaa
    18241 cagtcagttg tgttggttta ggttactcat ctgtaatacc atttacttcc aactctgctt
    18301 tcatttctaa caagtattga cgaatatctg gttcttttgc ttggtccgca atccgctcaa
    18361 attctgcaat tacttgattt atttcaattc gagcatccgt ctcctcattc attaaatatg
    18421 gatcgccagc gactttgaca ccattcttgc gaatatcaaa ttttaaccgt cgcaattgtt
    18481 cttctaattc tgggtctgac tgaatctttc caatcaccca ataaatttct ccaatcaact
    18541 catcataaac catgtacatc caactctttt aatcttctgg caatatcaaa aatgaccgga
    18601 actgttacag agtttccggc ttgcttatac aactgactat ctgaattgac ttgagaatct
    18661 cgatcaaaag cccaatcggg aaagccctga agtcgccaac actctctagg tgttagcttc
    18721 cgaatttgat actgatccgt gacgatcgct tgttggtctc ctgttagtaa ggtatgaaca
    18781 ctctgttttc ccagacgacc tcggcgactt gtggaattag gaaaagccag attcacactg
    18841 tcttctggct tcacctcttg atattctgtt tcattttttc gaatcatgat ttttgtacca
    18901 ccttgtttcg ttgacaaggt gggggcggtt ccagtaactt cataaactcg attaccttgt
    18961 tcaaactttc ccggtaatag tcctgctaca gagattccat cccttgctgg cagtgcgatt
    19021 ttgattcctt catcacctgt taaggttggc gctacgccat ctgaaccata gacttgtcca
    19081 cccattcctc gattggaagg attgatattt accaaatttc tgatgttttg atcagatgtt
    19141 gaagacggtc caatgatagg aaatacttgt tcggtacatg cgtctcgaga atgtccgata
    19201 aggaatatcc gctcccggct ttggggaatg taggcctttg agttaagcac ctaccactcc
    19261 acgtcatacc ccaatccatc cagcgttcgg aggatcgtct cgaacgtagc ccctccttcg
    19321 tgattgagca atcctcggac gttctcaagg aataaaagct taggtcggag aagagtggtg
    19381 aaccgagcga tttcaaagaa taaagtacct cgagtatcgg aaaatctttg ccgctttccc
    19441 gcaattgaaa aagcttggca cggaaatccg ccgcaaagga tgtccactgg tccgagggat
    19501 tgaataaact catctgatac acttgtgatg tcatgcattt ccacctcctt acttgtatca
    19561 tgaattgctt tataactacg tctagcaaat ttatcaattt cacaaaaacc gatacaatga
    19621 tggctcgcct gttccatacc taaacgaaag ccaccaatac cggcgaataa atctaaaaat
    19681 ctcatacatt acctcattca ttgcaaagaa aaaagccaag aacattttgc tcttggctca
    19741 tacattatta atttgtccta ctatttttta tttaatccaa ctaatttccg ttgtttttca
    19801 ttggcctgat cggctacata tttaatcacc gttttgaact cttttgcagt agcattttcc
    19861 gataaatccg caatgctctt attgtatttc tttacaattt tcgttacttg ttctttctca
    19921 gtcatgtaat tgaacctcca aatctttcct actataccct agtggtaaaa ataattctag
    19981 attatccgta gcataatgaa cttcggaaat attattcgta taatctttta ttatgatatg
    20041 aagcaataca tctggatgtt tactctttac ttttgcaatg ttctctcttg atttgaaaaa
    20101 agcgttaata aatgcctttt tcggcacatg acgtccctct gcaatttcac gttcttgtgt
    20161 aaatttccaa gcgattttag ggtcttgata aacatagaaa atcgtcactc gaaaatgttt
    20221 tttcaacgcc cgcgagatat ttttttcagc acttaatatt gcaaaagttg catccagaat
    20281 aaaagaatag ccatgatcta agacatatct aaatgcctgc tctaccaacc aagaagatgc
    20341 tttttgaaag agactagagt tttttccatt ataatcagga aactgggtgc gaaagtaatc
    20401 cgcatcaata atcacatggt tatcataatt ctcagctaat ccaatggcaa cctctgattt
    20461 tccagcccca ggactccctg ccataaaaac tgcgtctcgt ccaacttcgg gggatttccc
    20521 tttgataata taagaaataa acttatcctt atttgctttt gcatactcta aataagaatc
    20581 attactttcc atattaatta tcccctttct tcctactata taaaagtatt atacgttact
    20641 tgaagtataa agtcagtatt gaagatcact caatcattca tcttttctaa tttactaatt
    20701 gaatctaaga aatcataccc ttttggtaca agtggcgtat aaaactcact aatcacactg
    20761 ccacctgtat ccacataacc tcgacctttg atgtgcttca taaagaagtt tttttcgacc
    20821 tccccaaaca tcatggaata tccgagttca ctcatacgac ccaaagccac gcgaaagttg
    20881 aattgatcgc ggattccgtc tcctaaatat ttcgcatccg gcctttggca agccaaaatc
    20941 agaaagaaac cagattgacg acccaacatc acgatttgtt tgagcttatt caaaatcacc
    21001 gcactttctt tcgtcgttaa catctccata taagccacgt attcatcaaa gattaaaaag
    21061 ttgggtggaa gtccaagata ggcataattc tctcctgttt tgtagttaga catttctttc
    21121 attgccttgc tacgagccat catacgttca tagaaatctt ccacacaagc agaaatttct
    21181 tccttttgtg aataaacatg aggcatcacc gtacctaaat cagctaaatc tgcatttttg
    21241 ggatcgagga taaacaattc tgcatctgac ttcaatagtg cttcgataat ggtgaggagg
    21301 aaataggtct tccctccacc cgtgccacca gcgattaaca tatggggtaa agaatcataa
    21361 gcccatactt gatttttcat caatcgcaga gtcccatttt ctgccactac ttcgtctatc
    21421 ccaattcgat tggcgatcat atcatacagt aaagtatact ccacatagga gtctttgagt
    21481 tccttttcta ctaactcaca atacagtccg ctttctaact tcttttccaa ttttaaaagc
    21541 tgatcttggt atttcccaag tgaaatttga acgcgaatag acagtaatcc atctttcatt
    21601 cgataacaga ttttggggaa gtaactgata gtctctctgg ttcggctact attcaaatct
    21661 ttgaaaaagc cttcactttg agtttgtttc acttcatacc aatggttctc tagaatcatc
    21721 cgagctagct tttgtcgatg ccacaagctt cgccaatgat caagaaaaaa gtgaatataa
    21781 agcaatatca tagctcctga aaaagcgaga cttccaagca gacatactaa atcttttata
    21841 gaccaaacga tttcaatagt agaaagtgat agcttagaaa tatcaaattg tctaaactct
    21901 tgaaaataaa agacgctcat ccaaccgatg aacagagcga gtagccagcc aagaacaaag
    21961 tgataaacca agtgctgatc tcctgcgcgt atgcgatgtc ctttgtacat tttgatggtt
    22021 tccacctcca atcgaaaaag cccaatagga tttcattagg caatttcaaa aagttatgct
    22081 agtcatttac tgctacgagg aggggagttg tttcgtttca accaattgat ttaaaaagcc
    22141 ttcaatagca tccggcatct ccacaccaat ttcttccaaa atggattctg cctgccgaca
    22201 taagttttca tttacttcga caactataaa gaaagactct tcttctccta accagtctag
    22261 tacatcagag tcttcttcac tgtcgctatt ttctccaagt aaaccttgat gtataatcag
    22321 aaacattttt tcatcagagg ttaatgcttt aacgagttgt tcctcagtca gctcgccttt
    22381 tccatattga tcgagacaat ctaaaatatg ttcaacatta atttccataa tcttcaccta
    22441 tttctttctt tcattttggt tcgtaggatt tccttgattc ggctgccgct tcaagactaa
    22501 atcatccgcc ttaatgaacc aattaacggt agttccttct cgaaaaacat aattggcaac
    22561 ggtatccacg attggattga ccaactctac ctctgcatca taagcaaact cgcgtaaggg
    22621 tacattagct gggatactaa cttgaatcat tcgcccttgt gcagaggatt ttaaattata
    22681 ggttcgttct tttacctcat taccaattgt tccatcctca ttttgcttcc gtacttctcg
    22741 gcgtaatgcg gaaaaacgca acttcccaaa tgttaaacct gaatctacga caataccttc
    22801 tgttaatctc atcttctttt cctcctatgc tttcactaaa tcatcaacat acaacacgta
    22861 atcagtaaac ccacgattct caatctcata gcctttggca accaaatggg gattcacggc
    22921 ttttagcggt tggtcttgat caaaatcctt ttcaccggct tccgcagcta ctaccacctc
    22981 aatatcatcg gcccgttgct tactggaata caaatgataa ctgcgaccaa tcaccgtagt
    23041 attccgtcca tatccttctg ttataatttc tccttcaccg gcataactta actttccaaa
    23101 ggtttcagcc atatctggca cgacaaattt caattccatc ttcttttcct cttttcattg
    23161 ttagttttgg atacaaaaat agcgcgacta cttttttagg aggcggtcgc gcacgttggt
    23221 tcttaggatt tacttgtatc atctcatcac cttagttccg gcgattccag aaataatagc
    23281 ccgccgtcgc aaaaatcaaa gtaaaaccaa tgaacagtaa aacattggaa tttttctccc
    23341 cggtttgagg gaaggtcttc actgtgggac tagattcttg agagccactt ggaacagttg
    23401 gtgtttccgg ttgtttcggc gtacttagta tggttggaac ttcttttggt gttaaggttt
    23461 gagatttttc tttcaaatct tcattgtgtt ttccattgat attcccatct ttatcgtaat
    23521 tgatttccgc aaaagtaaac ttggttcctt ctggatattt tccggtatct acttttttcg
    23581 caagcacagt tttggtgaat tctttatcat ttacttcata atcaatcttg ccagatttcc
    23641 aaatttcttt gtttgtacca tccggtaata aagcatacag aattgtttcg aaagcttctt
    23701 ttgagccatc cagtacatca tgagtaatcg acacatcatc aaacatatcc accacatcac
    23761 catgagtaaa ggtctgagaa ccgttttcta ggtgggcctt tgtttggata gaaacatggt
    23821 gttccactgt acaactgaca gtttgggctt ggttattcaa gctaacatcc ttcgctactg
    23881 gcttatcgcc tgcttcaaaa gcttccttat tttcatacac atagttgaat aagacaatag
    23941 ttttatttaa aacttgttcg gcggttaatt tatgctgaat tttccaagtt cctgttttct
    24001 ctttgttcgc caacgttgcg cttgtttctg caatcaccac tggtttggct ttttcatctt
    24061 tttcttgggc agcttttgtc gcatccacat caatggcttg cgctaccaca taccagtctt
    24121 ctttgatttc atgtagattg taactcaatt tatcaactag ctcggtagaa tccagagaag
    24181 ttaattcttt gtttccgtct ttccaagtcg caagagaagt taaactatct tcttcctcag
    24241 gcaaatcata gagcattaaa cggttcaaac taacagaaaa tgctttgttc gtcagcttct
    24301 cgtaaggaac ggtcaccgtt ttaattggtt gtttttggtc ttgttcggta atggtaaaga
    24361 catactcact cttcacaaag tcttctttgt tttccttaaa agtagaacgg atttctaatg
    24421 gcgtaatctt ttgaaaacct tctggggctt ctacttcttc aagtaaataa tccccataag
    24481 gaagattttc aaacttgcca taaccatcaa accctaattg ctcgttataa gctgtggtcg
    24541 cttcatcttc ggcacctgtg atttcattgg tcccttccaa tggcgacact ttaaaggtca
    24601 gatcattgaa gccagtttcg gtagtgcccg cagctgatcc agcaaattta aagaaatcaa
    24661 agccaaagcg aatcacttgt tcttttgccg taacatttcg ggtaatcacg gcattttttt
    24721 cgctatcatc cacctttttg atggatacag gatactttgt ttcatcaagg ctatatcctt
    24781 cgggcgcttt tgtttcttgg caataatact cgttgatagc taaatgttta acggcaactt
    24841 ggttcttttc gtctaaagtc aaagtgaccg tttcatcaga acctttcgtt cccttcgcta
    24901 actctggttt aaaagcctca ctccatttaa cagcttttcc atccttagca gtaaacaagg
    24961 tgtattcagc accctcaaag actgccttac cttgtgcttt atccccagta tctttgtctt
    25021 ctttcgtcaa agtggtttcg ccagtgactt cttgattttg cccttttacg ttactggtaa
    25081 caggggctac ggtttgattg gcatacttca attcgacttt tacaggtttg aacgtattca
    25141 cgaacccatg actagcttta gtttcggtca cataataggt tcccaattcc aacgcattag
    25201 caatctcttt tggtgtttcc gcatgaccgt tttcatccgt ggtcatttct tgaacgattt
    25261 caccggttgg actgtctttg cgaatggcaa acgtattacc agctaaggaa taattgtcat
    25321 tccaaagatc actccctgtt tcaactccgc ttttatccag aatgatttgc cctttttccc
    25381 gtgcgttttt tgaagtcacg taaatggttt cgcctgcttt aatggtggta gtcatggggg
    25441 tggtatcaat cgtataaggc gccggtactg atttttcggt aatggttact tttgtaccat
    25501 gaggaatctc atccaatgta gcaatgcctt ctttgtcagt agtcacgtct tttgcaggta
    25561 aagtttttcc aaagtctaaa tggaaaaccg ttcctggtac aacatcaccc gattctttat
    25621 cgactttttt gatctttaaa gaaccctccg tttccacatc aattttgatt gtgtaggtat
    25681 taggtttatc aatcgccccg gccattaaag tctgttggcc agccttttta taggcgacag
    25741 gtgttccggt accagcagat ttcttaagcg tcagcacacc actttctttt gaattggcat
    25801 ttggggtgat tatcaactga ttaccattca cacgataatc aatgtttgcg gcattttcca
    25861 caacctcatc gaactctgac aaattcagat tattcgtatc cgtcacagta gtcgattgcc
    25921 ctaatactgt tttagccgta ctattatgga aggttggttt cttctgataa tcgtcaatgg
    25981 cttgatttat ttttgcctca atggctgcga tatttacggc actaccatct gatcgtttta
    26041 ttgagtgaag ggtataccca ttaacttctt gccagatcat cttctgtgcc acaatatgag
    26101 tatctgcatc tgtacctact tttttccata aaacggaaac taatttggct ttatcggaca
    26161 tatctggtaa cgggtttttc tcatagccag gagtgaactc attgtaaatc gggactcctg
    26221 gttcaataca gaaaatatct tgtttaaagc cgttgtacac tgcataatgc ggaacagtga
    26281 cttctgacat tggacgacca tcactaaaag ttccttcaac agcatattga tgtgctaaat
    26341 ctagttctac ggttaccgtt tgtggatggg taatttcatc agcaaaagta atcgtaggag
    26401 caattgctcc aacaattgct tgaacagcca aactcaaaat agttaataca cataatttct
    26461 ttttttgttt tttatacatg aaatgttctc ctttcaaatt aagcacaaaa aaataagatg
    26521 ctcgcttgaa catctttgtt tataaagtct ttttaaaatt tttattgact gaatagaatg
    26581 gatttgagaa tgaatgagcc taaaaattta atctaaaata cgaaatatac tgcctttaaa
    26641 ttagaacaca ttttagaaca caaacatttc aaatttaatc aaatataata a
//
LOCUS       DAXLPC010000031        26677 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.031, whole genome shotgun sequence.
ACCESSION   DAXLPC010000031 DAXLPC010000000
VERSION     DAXLPC010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.031"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..660
                     /locus_tag="ACF3UE_001279"
     CDS             <1..660
                     /locus_tag="ACF3UE_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFD3634703.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSNCGHKDGKKSLEIREWTCPICHTHHDRDINASINILTEGLRLHSMGL
                     A"
     gene            822..1010
                     /locus_tag="ACF3UE_001280"
                     /pseudo
     CDS             822..1010
                     /locus_tag="ACF3UE_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
     gene            1287..3347
                     /locus_tag="ACF3UE_001281"
     CDS             1287..3347
                     /locus_tag="ACF3UE_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFD3634704.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            3430..3999
                     /locus_tag="ACF3UE_001282"
     CDS             3430..3999
                     /locus_tag="ACF3UE_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3634705.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(4174..4980)
                     /locus_tag="ACF3UE_001283"
     CDS             complement(4174..4980)
                     /locus_tag="ACF3UE_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634706.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            5119..6633
                     /locus_tag="ACF3UE_001284"
     CDS             5119..6633
                     /locus_tag="ACF3UE_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFD3634707.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(7036..8019)
                     /locus_tag="ACF3UE_001285"
     CDS             complement(7036..8019)
                     /locus_tag="ACF3UE_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFD3634708.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(8024..8671)
                     /locus_tag="ACF3UE_001286"
     CDS             complement(8024..8671)
                     /locus_tag="ACF3UE_001286"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFD3634709.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(8756..9388)
                     /locus_tag="ACF3UE_001287"
     CDS             complement(8756..9388)
                     /locus_tag="ACF3UE_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD3634710.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(9404..9955)
                     /gene="coaC"
                     /locus_tag="ACF3UE_001288"
     CDS             complement(9404..9955)
                     /gene="coaC"
                     /locus_tag="ACF3UE_001288"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFD3634711.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(9952..10689)
                     /locus_tag="ACF3UE_001289"
     CDS             complement(9952..10689)
                     /locus_tag="ACF3UE_001289"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFD3634712.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(10686..11675)
                     /locus_tag="ACF3UE_001290"
     CDS             complement(10686..11675)
                     /locus_tag="ACF3UE_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFD3634713.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            11933..12475
                     /locus_tag="ACF3UE_001291"
     CDS             11933..12475
                     /locus_tag="ACF3UE_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFD3634714.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            12492..13577
                     /locus_tag="ACF3UE_001292"
     CDS             12492..13577
                     /locus_tag="ACF3UE_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634715.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            13589..14395
                     /locus_tag="ACF3UE_001293"
     CDS             13589..14395
                     /locus_tag="ACF3UE_001293"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3634716.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            14396..15223
                     /locus_tag="ACF3UE_001294"
     CDS             14396..15223
                     /locus_tag="ACF3UE_001294"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3634717.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            15220..16293
                     /locus_tag="ACF3UE_001295"
     CDS             15220..16293
                     /locus_tag="ACF3UE_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3634718.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            16721..19417
                     /locus_tag="ACF3UE_001296"
     CDS             16721..19417
                     /locus_tag="ACF3UE_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3634719.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            19482..19982
                     /locus_tag="ACF3UE_001297"
     CDS             19482..19982
                     /locus_tag="ACF3UE_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3634720.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            19994..20488
                     /locus_tag="ACF3UE_001298"
     CDS             19994..20488
                     /locus_tag="ACF3UE_001298"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3634721.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            20509..21318
                     /locus_tag="ACF3UE_001299"
     CDS             20509..21318
                     /locus_tag="ACF3UE_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD3634722.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            21315..22136
                     /locus_tag="ACF3UE_001300"
     CDS             21315..22136
                     /locus_tag="ACF3UE_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3634723.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            22187..24286
                     /locus_tag="ACF3UE_001301"
     CDS             22187..24286
                     /locus_tag="ACF3UE_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFD3634724.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            24283..25401
                     /locus_tag="ACF3UE_001302"
     CDS             24283..25401
                     /locus_tag="ACF3UE_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFD3634725.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            25440..26318
                     /locus_tag="ACF3UE_001303"
     CDS             25440..26318
                     /locus_tag="ACF3UE_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3634726.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            26464..26661
                     /locus_tag="ACF3UE_001304"
     CDS             26464..26661
                     /locus_tag="ACF3UE_001304"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFD3634727.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
BASE COUNT         8482 a         4632 c         5611 g         7952 t
ORIGIN      
        1 tatatttctt tgttatgcaa agaagaagtt cgcgaactac ctaaatctaa ttctgctgtt
       61 ggtattgacc taggtattat agactttgca attctttctg atggacaaaa aattgataat
      121 aataaattta cgtccaaaat ggaaaagaaa ctcaaacgtg aacaacgtaa gttgtcaaga
      181 cgtgccttat tagctaaaca aaaaggtatc aatctgtttg aagctagaaa ttatcaaaca
      241 caaaaacgta aagtagcacg attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat tatcaaaaat cacgatatca tctgtattga agacttaaac
      361 acaaaaggca tgttgcgtaa tcataaacta gcaaaaagta tttcggatgt ttcttggtct
      421 agttttgtgt ctaaattaca atacaaggct gactggtacg gtcggaaaat catcaaagta
      481 gataagtggt ttccatctag ccaaatctgt tcgaattgtg gacataaaga cggcaagaaa
      541 tctctcgaaa ttcgagaatg gacttgccct atttgtcata ctcatcatga ccgagatatc
      601 aacgctagta tcaatatcct gaccgaaggt ctaaggctac actctatggg attggcttag
      661 atcaaataaa caagaaccgt aggaactacg gggatagctt ggtaaataag aggcacctct
      721 gttagtaaag taatacgcta tcaagtatgc tctcttccca agaagctccc acttcaagcg
      781 taagaaaccg ttaggtttag ctaagtggtg agtagttcac aaattacaat attgtgattg
      841 agagtcgaat cacttctcgt acgaatattt atttatctga ttgtttactt gaaaaattta
      901 ataaagaaca gataatttgg aaaaatccac cgactccaga tgactgggaa tattttggaa
      961 ataccatcat cagagaaaaa aatagacatt taactgaaaa aatcagctag tatttatgga
     1021 tggcagcttt gtctcacata tttattagct gatttatgtt tttttcaaag aaaaggtaac
     1081 tagatataac tagatataac tagatatatt acttaacaaa attaaaaagt acataagtta
     1141 ttattccgat tttcttgaaa caataaaaaa tcaaaaaaaa tactctccta atagtccatc
     1201 ttcttttgat tttatttata taatgaaatc atcttatgaa aattactact tcatgtttag
     1261 acaagagtag ggaggactaa gaataaatgt gttcaaaaag acgttcaaaa caactaaata
     1321 aacacgcttg tcgtttagat aaggaacggt cgtgttctga aaaacactac gttaagttta
     1381 tgatgcgcac gatgctgatc agtttatctg taggtgtcta tatgcatgta cccgttcagg
     1441 caacgacaca aaccatcaag gtcgtacgta cctctgtttc tgagaccact gattccccta
     1501 tcactattac tcatactttc actgatgcaa atggaaaaca gctacttcct gcattgactt
     1561 cctataataa agtcagttat cctccaacga taaaccacta ctggttaatt cctaacaaaa
     1621 cattatggac atcggaaacc ggaagcagtg tgccgctttc tatcttttcc gatatgactg
     1681 atcctacaaa aggtgatcag ttaaaacaga tcactgatat tttgaatcat gctttgacag
     1741 atataaagga cggtggaagc gcacaagttt cttatgtata tgaaaaagat tattcacagt
     1801 ttgaaagaaa gaaaatcgat gttctggcag ggacaaaagt ttcgatatct gatctggtag
     1861 aaaggctgaa gaacgcagat ggaacacaag gagatatgtc caaagtaatt tcaaacaatg
     1921 ggaatatcgt ggatacgact aatacaggaa catctactat ttccttgtcc tattttgatc
     1981 caattgcttt aaaaacaatg actgcatctg ctgtgatcca tgttcgtgct gatcaaacag
     2041 ctatcaaagg aaaagatctt cacttaagaa caggagagag ttacgcccct aaagatcttg
     2101 ttgaatatgt aacaaaaagc gatggaactt caggaaataa agaagaaatc aaaatgaacg
     2161 ggacagtaga tactacaact ccgggagaat atcccgttgt attaacttat atagactcga
     2221 aaacatcaaa tgtggcagaa acaacagctg tagtttatgt agaagcatct gctgcttcat
     2281 cgactgtcat cactcatttt atagatagtc aaacaaataa agaacttcaa gcagaaacac
     2341 atatgagtag tgtaaatcgt attcctgatt tgcgcctacc tgctgaattt tctgatcgag
     2401 tgccaaatat agatttatcg acttatgaac aaaatgggaa agtcacttct atttctgatt
     2461 ggatgcaagc aaacggatta gacagaaaaa gtcactggtc ggagatcctt gaagtacttc
     2521 actcagaact gatgaataat aggaagcaat caggagggga aattaccttt acttatgttt
     2581 atataccaga caatcgttca ttagaaggtc atgatcttat tgttcatcca aacgaaaaaa
     2641 taaacaaaga agagttgatc caatcagcaa caaattcctt aggtaaaccc gtaccgttaa
     2701 aggatgtatc ggttacaatc aatgaagtac cattggagga tggttatttg accaaacaaa
     2761 caggtgattt tacgattatg tatagttatc atgacccgta ttcactccaa gaactccatg
     2821 ctcagtcact attacatgtt ttaccattaa acaaacagat agatcaaaaa gaacaaaaaa
     2881 gacaagaaga aagcttgtca gaaaaaaaac aacaaatggc ccatgcagtt tctccaacag
     2941 ggaaagtaaa acaaacaaga agcctagagt tagcaagaat atctagaaaa atctcagaat
     3001 ctaataaaac gataaggcaa gaagctcatt tggccccaca agtttctgga ttggaaaatg
     3061 aaattttaga gcctaaaata aaacaacaat cagaaaaaga atttgttgct aaacagtcgg
     3121 aagatcagaa ggaatcagat gaccagaagg aaacgaagaa aaaacgcttg tcaactattg
     3181 attccaccga tgagcatctg cagccgcaag taccacttcc tagtccggga acacccgcac
     3241 ctggtggagg tattccttct tctgctttag gagatttcat gcgaggtatg gcaggaacat
     3301 gggtatacgc taatcgaaat gaatttgacg cagatgactg gttctgattt atatctctat
     3361 ctgttatagt caaataagta gctgagtcat atgttatttg gcataatgga gacgaggagg
     3421 gatagaaaaa tgttagataa aacgttacct tacgcagaaa tctggatgac aagaccactt
     3481 caacaaaatg ttccaatcac gcctttagcg gaaggttttg aatttcgatt ttatcaaaaa
     3541 gaagatgaat ctgcttgggc ggagattgag acttccgttg gggaatttca aacgacagat
     3601 gaagcacttg agtattttca acaaaacttt gctccttatc ctgaagaact tgaaagaagg
     3661 atgttttttg tagagacaaa aaaaggagaa aaagtagcaa cctgtaccgc ttggcgaaaa
     3721 aaatcaagag agcaagtgta tccggttttt cattggttag cagtgaaacc agattaccaa
     3781 ggaaaagggc tcgcaaaagc attgactgcc agagtcttgc aagaatttcc taccctccat
     3841 acggacggac caatctatct tcacacacag acatggagcc atcaggcgat tgctctttat
     3901 aaaaaaatgg gttttacttt tattgctgaa aatctagacg gcacacctaa tccagattat
     3961 gaaaaagtta tgcaggtttt aagtaaatta gataaataac gaaatggtga aataagtcct
     4021 cagtattggg ataaaaaacg aaatagtcat tcctcatatc ttactttttt gagttaatac
     4081 tatcggataa ctaatggcat gccatacatt caaaaaagaa ggggcagtga caaaagtatt
     4141 gtcactgccc cttctcttgt tttttagcat gttttatcgt ttgatttttt taggaataaa
     4201 attcttgatg aacgtaaatt tttggtaatc gtttcgacta tagaggtaac caaatacact
     4261 gaaaacaact gctccaataa aattaacaaa taaatccttc atagtatcca tgattcccac
     4321 gtctaagtaa ccattttgga tgattgtttt atctgtttta ccatctgcat tttgactttc
     4381 aatgattgtc cgagtgatat ctggaacatg atagacagtg tttccgtctt tacttaactc
     4441 cacactattg atttgctgga tgatcgtatc tttttgcata tcgaattgca gtaatttatc
     4501 tgctgaaaat tccacaaact cccacataac accaactgtc atcgaaaaac agaaggaaac
     4561 aactgctagt aataaaggag tcaagttcat ggtttttgta tttttattga gcaaataaac
     4621 aagggaaaag ccgacacccc cagctaaaaa tccgctgaat gcatgtagaa aagtatccca
     4681 cattgaaaaa tagccataaa aatcacttaa ctctcctaaa actgttgaac taaaaataaa
     4741 agataacaaa atgatttcta gcatatttgg aatctgtatc tttaatatct tttccagaaa
     4801 ataagggatt tcaaataaaa ttaatgtcag taataaaagc attgtatttc cccagtgttg
     4861 gttccagacc tgatccacta gcataataac gacgatgata cgtaataaaa tatagattcc
     4921 gtttgtgatt ctacctgcag tttttgtact gttcgtaaaa aaggttttca aatgattcat
     4981 aaaataactc cttcatgtat atccttaatt atactaagaa gcgtgtgttt accaaagcta
     5041 tatgacttaa agaaaaacag agttgatatt gtgaaaaaaa tcacttaata tagtataagg
     5101 agaaaagggg ggatacaaat gaaaaaatta gttgctggtt tattaacagc cgttgcactt
     5161 cttgctatga gcgcatgcgg cgcagatcag aaaaatacag cgcagacaag ttctagtacg
     5221 aaggaatctg ccgaagtatc atcaggcgct tctgaacaag tatatacaga tccaaaagaa
     5281 atgaaagaat cttatgatgt cgtgattatt ggagctggtg gtgcagggat ggcagcagct
     5341 atcgaagcaa aagatgctgg gttgaatcca gtaattttgg aaaagatgcc tgttgccgga
     5401 ggaaacacat ctaaatcatc aagcggtatg aatgcttcag aaacaaaatt tcaaaaagaa
     5461 gaaggaatca aagactcgaa tgatgccttc tatgaagaaa cgctaaaagg tggtggagga
     5521 acgaatgata aagaaatgct tcgatacttt gtcgatcact ctgctgatgc ggtcgattgg
     5581 ctagatcaaa acggtatcaa actggacaac ttaacgatca ctggagggat gagtgaaaag
     5641 aggacacatc gtccgtctga tggctcggct attggtggat acttagtgga ggggttattg
     5701 aataacgtcc atgagcggga aatccctatt tttgtcaacg cagatgtgac agacattaag
     5761 aaaaatgggg aaacggtcaa tgaagtgact gtacatgttc aaggagaaga accaaaagag
     5821 gtcaccggaa aagcaatcgt agttaccaca ggcggttttg gtgccagcaa agaatttatt
     5881 gaaaaatatc gtcccgattt agctgattat attacgacaa atcaagaagg atcaactgga
     5941 gatggtatca ccatgattga aaaattaggt ggacaaaccg ttgatatgga taaaatacaa
     6001 attcatccaa ctgtgcagca ggatgagggg gtcttgattg gtgaggttgt tcgcggagaa
     6061 ggagcaatct tggtcgatca agaggggaaa agatttgtca atgaaatgga tacaagggat
     6121 aaagtatctg cagcaattac agcattgcct gaaaaatcag cttatttgat ttttgaccaa
     6181 ggcgtgcgtg atcgtgccac agctattgaa ttttatgacc aaaaaggata tgtcacaact
     6241 ggaaagacaa tggaagaatt agcagaaaaa atcgatttac caaaagaaac actagcaaaa
     6301 acagttgatg gatggaatac ggatgttgcg gagaaaaaag atgctcaatt caaccgtgcc
     6361 acagccatgg aacatgactt atcgtctccg aattattatg cgatcaaaat cgcaccagga
     6421 atccattaca cgatgggcgg tgtgaaaatc aatacgaaca ctgaagtatt agataaagaa
     6481 aaccagccaa ttagggggtt atatgctgct ggtgaagtca caggtggctt acatggaaac
     6541 aaccggatcg gtggaaattc agttgcggag atcattattt ttgggcgaca agcgggcata
     6601 caagcagctc gatttgcttc ggaaaatgaa tgaaatagaa cgtaaataaa aagaggttgt
     6661 gaaatcagcg ttttgagcta ataccgaggg tcagctgatt gaacactgtt tagtgaagag
     6721 gttgtgaaaa agctgccctg catcaagtaa taagaacagc caagtaaaaa cagcttctta
     6781 tgtttttaac ttggttggac ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     6841 gaaaaagagc gtgggacaaa agtaaagaac acttttgtct cacgctctaa acacgtataa
     6901 acggcggaag cagaagaaat tccttcggaa ataagctgaa attcacaaaa atttgaaaag
     6961 caattttcgt gaatttcttc ttatttcttg gagttaaacg cttctgtccc agcctctttt
     7021 ttgatcagca tgattttatt cagttatctt caaaatgatt tttccgatgt ttttgtttgc
     7081 ttccatatat tcatgcgctt gtttgactgc gctgaattgg aatgtacggt caatgattgg
     7141 ccgaatcttg ccattttcta gaaaaggccc agctttttgc ataaaagttt gtgcgagctc
     7201 tgctttatac tgatcacttc taggtgtcaa taatgtacca agcagttgga cacgtttccc
     7261 aatcaataca ccaaggtcta tctcaggcac gatggtccca cctagcatac caatcaagac
     7321 ccaacgtcca tcaacggcta tagaagctaa attcttttcc cagtaagaag cgccgatgaa
     7381 atccaaaata acatcgactc cccgaccttc agtgattttt cgtacctctt cttgaaagtc
     7441 ttgtttttta tagttgatca attcatctgc accaagttct ttacaaaagg cgagtttttc
     7501 ttctgatcct gcagtaacga tgattttcgc gtgagaaagc tgtctagcta attggatcgc
     7561 tgctgttccc acaccacttg ctcctgcatg gatcaagaca gtttcgcctt cttgtaattt
     7621 tccaagccag taaagtgttt gataagcagt caaaaaaact tctgagattc cagcagcaga
     7681 aacatagtct agcgtatcag ggagaaggat tgcacgatcg gcaggcatca cagcatattc
     7741 ggcataacca cctagattga ctaatccgta tacttttgtc ccaggagtaa aagtggagat
     7801 atcactttta ttctcaacta cctctccagc tacttcgact cccaaaatag ggtagggagg
     7861 tttcaaagag actgattctc ttttcataat atctgttcga ttgacagctg ctgtatggac
     7921 tttgatcagt aattcgcctt gttttggttt aggaacaggc acttcaattt gttctaatac
     7981 atctacagaa ccaggatgct tgattgaaat ggcacgcatg gatctattcc tcctttgccc
     8041 attcttggaa tgctgtattc aactctttgc taccttcaga aagtactaga gtcgtacgag
     8101 aaatatccgt ttcttccact agagcggcaa gtacagcagc aactgtagag cgagtgatcg
     8161 tttttgatgc cttctcatta ggcttagtta attgaatgga agtaacttct tcatcgttag
     8221 tcaatgtgac tggttgaaga atgacaaaat ctaagttagt tcgtttcagc cattcatctg
     8281 cataatgttt agtaatataa taatctgtca tggactcagg ccattttgct ggttcatctg
     8341 cataaacagc actgaccatc agatagcgag agacatgcgc attttcagct gcgatcactg
     8401 ttttgattgc gccatccaag tctacttgca gaagattctt tccttgagag ccggcagcaa
     8461 aaatcaatac atcgatgcct ttgaatgctt cggtcatttt ttccacggac caagttaaat
     8521 caaaagagac atacgaaaca ttctcttttt ttactaatgt ttgggaagca acatctctca
     8581 cccctgcaaa aatttcatgg gaacttggag ctaaatcttt tatcaggtgt cggccaattt
     8641 gtccgtttgc acctacaaca aaaattttca tttggatcat cctttcgacg tcaaatcttt
     8701 ccattcaata gtaacaccaa aagagaaaaa aatcagagat cggctacgat gactatcagt
     8761 tagtaagaga agggtgcttg aagtatctta acaagacatt gcatactgct gcagtcgcaa
     8821 gacctgcgac gattccttca ggtataccac ttgtaaaaat aaccgctaga atagctgaat
     8881 aaacagcatt taaatttgtt ccgatgactt tggcataatc ttgctggaat aaaaagtaga
     8941 tcatattcat cactaaaatc gtattggtca atgaaccgga aagtccagct aagaataaag
     9001 aaacggaatc tgctttttgt ttcattagtt tgcgcagacc tttataaacg aaataaggaa
     9061 ccaccccaat caagatgcga ggaataaacg cgatcagcaa ggctttccag cttccatgtt
     9121 ctgttccgat gactgggata aacggagaaa agacaaaaga caaaggtgtt tggataactg
     9181 tgctacggat catgctgatc agtccaaatg taccgccaag aaaagcacct agtcttggtc
     9241 ctaaaacgat cgaagcaatg attacaggaa tatgcatggt tgttgcattg attggaccga
     9301 tagggataaa acctaaaggc gtaacagcta ataaaatcaa aatagctaaa aacatcgcag
     9361 ttaatgtaaa gttttttgta tttttcataa gtactccttt tttctaagca tttctttcat
     9421 taagagtcag catgacctgt tcgatgatcg tctgaatatc agctaaggca ccttttccaa
     9481 aatctccaca agctaaaaga gattctcttg gttcaatttc ctgatagccg acagatctca
     9541 atgtttccag attacgctga gtgatcgggt tttgatacat attcgtgttc atggcagggg
     9601 caatcaattt tggtgttccc actggaagcg ccattgcgac tgttgaaaga agatcgtctg
     9661 caatgccgtt tgctagcttg ccgataatgt ttgctgtagc aggcgcgatg agaaacaagt
     9721 cagcttgttt tgctagttcg atatgattga ttacctgcgg atttgattct tgcatgacgt
     9781 ctgtatggac tgcgcgcttc gacagagatt gcaaggttaa tggcgtgata aaatgtgtgc
     9841 tgcttttaga cataatcaca tctacctggg cacctaattt gacgaattga cttgtaagat
     9901 cagcgctttt gtaagcagaa atacttccag taacgcctag taagatcttt ttcattttga
     9961 ttcctccagt ctaattttct cagtaatcaa tgcagcaatc tcagatttac tttgagcttc
    10021 ttccactgtt ccatctttag ataagagata gccgtggtgt gtctcgccat ggatttccgt
    10081 caaatcattt gcgaaaataa aatcagtttt gttatttatc agactatttt ttgcgactgc
    10141 cagaagagat tcctttggta catctactaa tagtttgaaa ccaatgattt ttgcttttgg
    10201 ctgccattca cgtagataag aaatgatttt tggtgttttc ttcaaaacga gcacaagatg
    10261 ctcggtgtta gaagagatct ttgaaacagt ggtatctgtc tgttcatttt ccgcaaacca
    10321 attgtccagt tcttcttgcg ttgaagaagt gggtaggttt tttgccagct gttcttctga
    10381 aaaactaaaa gcaggagtaa aatcactgac tgccatactg tggataatcg catcgtagtg
    10441 ttcttttttc gttagttctt ctaattgtaa aaataagtcc agtgcagatt cgatcgtata
    10501 aatcgttata ttggagtgtc ttttcggttt cagtgcttgt ttcgtagtca cgtaatcgat
    10561 tgtggtatcc ggattggcag ctaaataatc agctaatgct tgccctaatc gtcctgtcga
    10621 atgatttgta atagcacgta cttgatcgat tttttcagtc gttcctccag ctgtgattag
    10681 aatcttcatt tatggtcacc tacatttact agtgttcttc cttggtgtgt tccagcaagt
    10741 agtttagatg ctgtttcagg caattgatcc agagtaatct cttggacgac cagttcatct
    10801 gcaatctgca aatccgccat ctgttgccat aaagaaagac gttgatctat tggtacattg
    10861 acagaatcaa ttccaatcaa ctggatgttt cgcagaataa aaggcaagac agtcgcgttt
    10921 agtttgattc ccccagcatt gccacataaa gctactgcac cgttataaga gatcaatgga
    10981 agaagactgc ttagctgctc gccacctact gtgtcgatga catagtcgat ttgctgtttt
    11041 cctaaagctt ttgttgtctc tggcagaaat tcatcaggtc gtacgacttg caaagcacct
    11101 agacttttta gccatgtgac agactcttct tttctggaaa aggcaatgat tgactggaat
    11161 cctagtttat gtaacagggc tatcgctgta ctgcctacac cgccagaagc accagtaacg
    11221 acaacttttt tatcggaggt cataccttga cggattaaag cgttcacaca caacatagca
    11281 gtaaaccctg ctgtaccaag gatcatcgct tgacgcagcg tcatattttt tggtagagga
    11341 actaaccagt ctcctggtac tttttgatat tggctataac cgcctggatg ggtgacgcca
    11401 agcccaaaac cagtagcaag tacaagatct tcttttgaaa aacgtggatt gttactttgg
    11461 acgacagttc cggataaatc aatccctgga gtcatcggat atgttcgtat cacctgacca
    11521 gactcgctca ttgccaatgc atctttataa ttgacatcag aataggcaat ttttaccaag
    11581 acttcatttt cagccaactc agtaaatggc agatcactga ttgctgtatg gaaaacaggt
    11641 tcctttatta cctgaaaaga tcgaaaagcg ttcattcgtg agacactcct tttaaaattt
    11701 tcttttatca taccataaag cctactcttt tattcttgtt cttccgtaaa tttagacaaa
    11761 aattaggtga aaaataaaga atcaaacaac tagaatttat tccaaaagat aaagaaatat
    11821 tcagcaaaaa aaattttaca aatggttgcc tttttcaata aatttcgtat actaatacga
    11881 gtggtagtaa acaggaagtt tactattaga aaacttcgat tcggaggaaa ttatggaaat
    11941 tggtgagaag ttaagaaatt tgcgcatcca aaagaatttg acacaagaag aactaggcga
    12001 acgcacagat ttgtcaaaag ggtatatttc ccagttggaa cgagatttaa gttcaccatc
    12061 aatggaaaca ttcttttcta ttcttgaagt cttaggtgtg actccagaag aattttttca
    12121 tcaagaagca gcgaatctgc aagtggttta ttcaaaagaa gatcatacgg tttatttcga
    12181 tgaagaaaac gggtatgaat tggaatggct cgtggctgat tcgaatgaaa aagaaatgga
    12241 gcctgtcttg ctgacttttg aaggtgcagg agaatataag acgtttgaac cttcattatc
    12301 tgaaacgttt atttttgtat tagaagggga attagagtta agcttaggag agacggtcta
    12361 tgtggcaaaa gcaggacagt cgatctatta tcaagcgaca aaacaacatc aattaaggaa
    12421 tcatctcaaa aaacgaacaa aagtattgat tgttgcaacg caatcatatt tgtaatatag
    12481 ggggtaaaaa cgtggggaaa ccaatcattt catttgatca agtagtgaaa cgctatgatg
    12541 atgaaacagt attaaaaaaa gtaagttttg agatcgaaca aggaaaattt tatacactgc
    12601 ttggtccttc cggctgtggt aaaacaacga tcctacgtat tatagctgga ttcaccgaag
    12661 ctacagaagg ggacatctat tttgaaggga aacggttgaa tgatttgcca gctaataagc
    12721 gacaagtaaa tacagtcttc caagattatg cactttttcc tcatatgaat gtttttgata
    12781 acgttgcttt tggattgaag atcaagaaaa tgtccaaatc agatatcgaa aagaaggtaa
    12841 aagatgcttt gcgtatggtc cagcttcctg gatacgaaaa acgggagatt agtgaaatgt
    12901 ctggtggtca aagacagcgt gtagcgattg cacgagcaat tgtaaatgaa ccgaaagtat
    12961 tgctattaga tgaaccgtta tcggcgcttg atttgaaact acgtacagat atgcagtatg
    13021 aactgcggga tctgcaacaa cgattaggaa tcacgtttat ttttgttact catgaccaag
    13081 aagaagcgtt ggcaatgagt gatgagattt ttgtcatgaa taaagggaaa atcgtccaaa
    13141 gtggtacacc cgtagatatt tatgatgagc caatcaatca tttcgttgct gattttgttg
    13201 gggagagcaa tatcgtggac ggtgtaatga tcgaagataa tctagttgag tttgttggta
    13261 agcaatttga atgtgtcgat ggcgggatgc gtctaaatga accagttgaa gttgttttac
    13321 gcccagagga tttgacgatc acgacaccag ataaaggaaa actagtcgta acggtcgata
    13381 ctcagctgtt tcgtggtgtc cattatgaaa tcatctgtta tgatgaacag caaaatgaat
    13441 ggatggtcca ttcaacgaaa aaagctaaag aaggaagcaa agtaggattg gcctttgagc
    13501 cagaagatat ccatgtcatg cgtttcaacg agtctgaaga agaattcgat gcacgtcttg
    13561 acagctacga agaatagggg ggacaagaat gaaaacaatg cgcaggatct attccgtccc
    13621 ttatattttg tggctcggtt tattcgtgat cgcgcctgta ttaatgatca tttatcaatc
    13681 tttttttgat atgaatgggc aattcacgct gaataattat ctatcttatt ttacgtcggg
    13741 gacatcgctt tctatgacga tcaattctgt atggtatgca tttttgatca cgtttttcac
    13801 gctgatcatc agttacccga ctgcttattt tttaacaaaa ctgaagcaca agcaattatg
    13861 gctgatgctg attattttgc ctacatgggt gaatctgctg cttaaagctt acgcatttat
    13921 tgggattttc agtgtgcacg gcagcgtgaa tcatttcttt gattttatcg ggatcgggcc
    13981 gaaacagata ttattcacag acttcagttt tctgttcgtg gcaacgtata tcgagattcc
    14041 atttatgatt atgccaattt tcaatgcatt ggaagagatg aatccttctt tgatcagtgc
    14101 tagtagagat ttaggcgcga atagctttga gaccttccga cgagtgattt ttccgttatc
    14161 attaaatggt gtgaaaagtg gtgtccaagc agtatttatt ccttctcttt ctttattcat
    14221 gctgactcgt ctgattggcg gaaatcgggt gatcacttta ggaacggcta tcgaacagca
    14281 tttcttggtt acacaaaact gggggatggg ttctacaatc ggtgtgattt taatcattgc
    14341 tatgttcatc gtgatgctcc tgacaggcga gaagaaaaaa ggaggtcgct cataaatgaa
    14401 aaaatttaaa tggtcgtatc tttatttagg gatcgtcttt ttattcttat atgcaccgat
    14461 cttctatctg attttttatt ccttcaatga aggaggaacg atgaacagct ttacaggatt
    14521 tacttgggaa aattatgaag ctgtttttga agatacacgt ttgatcatta tcgtattgaa
    14581 tacgttcatg ctggctttct tatctgcatt gatcgccacg atcatcggga catttggggc
    14641 tatgggaatc tattacacga aaaaacgacg tgcacggaca gcgttgttga gcatgaataa
    14701 catcttatta gtctctcctg atgttattat cggtgctagt ttcttgattt tctttacact
    14761 actaggattc ggattaggtt ttcagagtgt attgctttcc catattgctt tcagcattcc
    14821 aatcgtcgtc ttgatggtct tgccaaaatt gcaggaaatg aacgattcaa tggtcgatgc
    14881 ggctagagac cttggtgcta ataatttcca agtagtcaaa aatatcattt tgccttatct
    14941 ttctccagga atcatagctg gatattttat ggcatttacc tattctcttg atgattttgc
    15001 ggttacattt ttcgtcacag gaaatggctt tacgacgctc tcagtagaga tctattctcg
    15061 tgcaagacaa ggaatcagtt tagaaatcaa tgcgctaagt gcgttagttt tcttgttctc
    15121 catgatattg gtcattggat actactttat tagtaaagaa aaccgtccaa aacggctgaa
    15181 gaaaaacaga agagtacgcg agggggtggc acggctgcga tgaaaaaatt acaatctctg
    15241 tttttaggta ttctcatcat tattgcggtg ctgctgcttg gtgttcgtca acttgaaaaa
    15301 acaagtggca tgagtggagc aaaggtactt accatctata actggggaga ttatatcgat
    15361 cctagtttga tcacgaaatt tgaaaaagaa tatggataca aagtgaatta tgaaacattt
    15421 gattctaatg aagcgatgtt cacaaaaatc cagcaaggtg ggacaaacta cgacatcgct
    15481 ataccaagtg aatatatgat ccaaaaaatg atcaaagaaa aactagtact tccattagat
    15541 cattcgaaga tcaaaggatt aaataatatt gatccacgat ttttagactt ggattttgat
    15601 ccagataatc agtattcgat tccatatttt tggggaactt tagggatcgt atataacgat
    15661 aaattctttg atgcaaatca aattaagcat tgggatgatt tgtggaagcc ggaattaaaa
    15721 gacagtttga tgctgattga cggtgcacga gaagttatgg ggctttcttt gaatagttta
    15781 ggctattctt tgaatagtaa gaatatggca cagctgacag aagcagcaaa taaattgaat
    15841 catttaacac caaatgtcaa agcaatcgtg gcagatgaga tcaaaatgta tatgatcaat
    15901 gaagaagcct ccgtggcagt gacattttct ggcgaagctg ccgatatgat gtgggaaaat
    15961 gaacatttac attatgtgat cccaccagaa ggatccaatc tttggtttga taatatcgtt
    16021 atgccaaaaa ccgtgaaaaa taaagaaggt gcctatgatt tcatcaactt tatgctagaa
    16081 ccggaaaatg cggcacaaaa tgcagagtat attggttatt ctacaccaaa tgaagaagca
    16141 aaagcgttat tgccaaaaga catttcgtcg gacgaacaat tctatccatc tgatgacacg
    16201 atctcccatc ttgaagtcta caaagatcta ggatcgaaat acctaggcat ctataatgac
    16261 ctattcttag aattcaagat gtataggaga taatggcaaa actcagtaag aatggggact
    16321 tatcaacgtt ctaaagagct aaaaatcgtc ctttttctat ctgagttttc caatcttcta
    16381 ccaaaagcgg atgaaacgcc gctttttttg tgttatttta ttttttctac cacgtttttc
    16441 taccagagaa aagtggacaa aaccattgta aaatagggcc cgagacgggc tagtaaatct
    16501 aagattgaaa aagttacaga aggataaagt aattggaaac tatgcaaata tacttaaccc
    16561 ttctgtaatc tattaataaa actaatatat gaatccagtt caatatttgt agctatgaaa
    16621 aaacataaaa atcatattag ataaaaacta aattggtaga taaattattt tgtcagatat
    16681 ctgaggcaaa tattcgacta tttgtgtttc aaagtaaaaa ttggaataca aatatagaat
    16741 agacatattg cagccgatag tttattatgc ttttagacac attaaactgg aggaaaaaat
    16801 gaaaaagagc gctaaagatc gagtttttga tgagctgata cgactaacag ggaatatgtc
    16861 ttctgtcact gccgagaaaa tttcgaagaa tctaggtatc tctcgtcaga atgccagcca
    16921 ttatttgacg agattagtgg aagataaaaa ggtcgagaaa ttaccgggaa agcctgtttt
    16981 gtggaagcct ttagatgaat atgcggttgt agataatacg gagcaaataa acgaagcctt
    17041 tcattctgta gttggtcatg acggaagtct gagagaggtc attcaaaaat gtatagccgc
    17101 tgtcaaatat ccgcctaacg gactcagtgt attaataaat ggagccacgg gtgttggaaa
    17161 aagtttttta gccacaaaaa tttttgaata cgctatccat gagcaaatta ttgaaaaaga
    17221 tgcaccattt gctatcttaa actgtgccga ttatgcggac aatcccgaac tgctttcggc
    17281 aacactgttt ggatacaaga agggggcctt tacgggggct gaaaaggata ccgatggttt
    17341 attggcaacg gccaacaacg gctatctttt tctcgatgag gtccatcgcc tatcgaaaga
    17401 aaatcaagaa aagctctttc tatttattga tactggaaac tatcgtccag tcggtgaaaa
    17461 tgtaaattgg cattctgcta aggttcgttt tattttcgcc acgacggaaa aaggtgaaaa
    17521 ttatttatta gacacctttg atcggcgtat tcaaattagt gttatgttgc caacttttga
    17581 agatcgcccc attcgagaac gattagagct gattcaatta ttttttcaaa atgaagcgga
    17641 tgttttacaa aaagatatta ttgtttcaag agaagccttg tctttaatgt tatctcatcc
    17701 ctttagtggg aatattggta agctgaagaa tatcattaaa atcagttgtg cggatgtgta
    17761 tagtcgaaca caagaagaac cattaacgat tgggaaaaat gagatcttga ttcagttaaa
    17821 tatgctggaa tccgaagtag aaagcttgcc gattgctagt ttattgataa agaaaaatca
    17881 aaagataaaa acggatcgaa tcaaaccgtt tgattatgat tcgattttgg aaaaaattac
    17941 tcagctgata aatgaaggta atttcaatga aaatttttct tcgataaaga atgaagtaca
    18001 gcatttggtg catcacattg ataaggattc ttttttatca atgagtagaa aattgatgat
    18061 tcagatgttt agaaaggtct gggtatccgt tttaggaaaa acgtacggat tgacgacgag
    18121 tggacctgtt gcagaaatta ttagcagatc ctatgtcatt tccccaagct ataagacaga
    18181 cttaaccggg ataaatcgta cattagctgc aaatctacct cggacgactt acttatgtaa
    18241 tcagttcttg gagcatttac caccgctctc agaaaaggac gagaactttc taagactgct
    18301 tattgtcgtg actttatctg attatgtaga tgaatccatc gagctgaagg gcctgttgct
    18361 tgctcacgga gatagtacgg ctagcagcat tcaagcagta gtgaatcaat tatgcggcaa
    18421 ttatgttttt gaagcgttgg atatgccagt agagagtaat gtgtcagaga ttgtcgaatc
    18481 gacaaggaat ttcgtgaaac ggcaagtgaa tacagatagt ctagtgctga tcgtagatat
    18541 gggctcttta aatcaaattt acacacagat caagaacgat ttaaaagggg agttacttct
    18601 tctgaataat ttgacgactt ccattgcact tgatattggc ttgaagatga cgatgaatgc
    18661 gccatttaaa cagattgcgg aggatgcagc agacaagtat tcaatcaatg ttcaatactt
    18721 tgaaggcttt tctcaaagta gcaacattat catttcctgt atgtcgggtt tggggatttc
    18781 ggacaaattg aaagatgttt ttcgtcatca tttatcggat gaatccatcg aagttttcac
    18841 gaaggactac agagaactac gtgaattaat cgaccaaaat gatgaaactt attttgacaa
    18901 gacaaaattg gtcatcacga cttcggatct tccacgttcc ttttcaattc ctaatattaa
    18961 tgtttatgac atcttagacg gtgatggagc agccaatttg gagcatattt tgagtcctga
    19021 aatgaagccg gcagaattta accgcttgat tcaggagcta gtaaaattct tttcgttgga
    19081 aggaattgcg gaccgtttga actttctgaa cccaacgatc gtgatgagtg aagtggaaac
    19141 agtcatttct aaatatgaaa attactatca tttcacttta aatggccgtg taaaactaaa
    19201 tctctatatg catacggcat tgatgatgga acgtttattc ttggctcgga cagaaaaatc
    19261 tgaagaaccg aattatgatt tgaaaccaga tgaagatgaa ttttattatg tttctagaag
    19321 tatttttcaa tcaatggaga tgaaatataa ttttaaagtc aatgcttatg agctttcgct
    19381 gctctatgaa ttattaggac cgtatattca aaaataaagt gtctaaaaaa gtgtctaatc
    19441 tgtttttttt aggttagaca ctttttttaa tgtgaattaa cgtgattaaa ccaatgtttt
    19501 taaaagttgg cacaggaatt gcttatataa aagtgaacag aaagaaagga attaaccata
    19561 tgaagaaaat tctaatagcg actcacggtc acttagcttc aggctttctt agcagtattc
    19621 aattactgac ggggaaggtt caagagatta cggtgattaa tgcttatgtg gatgagtgtg
    19681 attttgaaca ggagttgaat gtatttgtaa accaggtgaa cgagcaggat cagatttttg
    19741 tttttaccga tttatttggc ggaagtgtca atcagaagat taccaaaacc tttttggaga
    19801 aagagattgc tgtaactatt ttgtctggct ttaatctgcc aattctgctc gaaatagtat
    19861 tggcaaccaa ggaattaaca aaggaggata ttcaggaact ggtaaataaa tgccaacagg
    19921 aattaaagat gaccattctt gatgaggtac atgtagtaaa tgaagaggaa gatttttttt
    19981 aggaggaaga aaaatgatta aagcagtgcg aattgatgaa cgattaattc atggacaagt
    20041 agcgatgact tggacaaaga gtctaaattt aaccgggtta gtagtagcaa gcgatgaggc
    20101 ggctaccaac gatattcaaa agatgacatt gaagatggct gcaccatcga atgtcaaagt
    20161 cattattaaa acagttgatg acgcgattca tttgttaaaa gatccgcggg cgaaggacat
    20221 gcgcttgatg gttttagtcc ctaatgtcaa agatgcggta aaagttgcga aagctttccc
    20281 aacggaaatc gaattaatga acgtggggaa tgctgggaaa atgacaccgc catcggaaga
    20341 taagaaaacc ttatcaaagg aagtgatgtt aacgacgtca gaaattcaag acttaaaaga
    20401 attagttgaa ctttatccag ataccgtttt tcagcctaca ccggcgatgg aaaaacgttc
    20461 agctatctct attttgagtg atttttagaa aaaggaagga gaaaaattat gtatgatgca
    20521 tttgtagtcg ctttggccgt ttttattgga gttgctggac atgaaatgtt cgggatgtcc
    20581 atgctgagtc gtccgattgt tgttgctccg ttagcaggag cgttgatggg ggatttgcag
    20641 acggggttga ttgtcggggc gtcactagaa gccatcttta tgggtgtcgt caatatcgga
    20701 atctctagta cggcggagcc ttctttggct gctgggctgg ctacagcgtt cgcaatcaaa
    20761 atgggaggaa acgtggatgc gattattccc attgtctttc cactagcagt attaggatta
    20821 cagttaatga atatgatttt ttcttttgta tgtggaccga tggctgctaa atttttcaaa
    20881 tttgcaaaat ctggtgatca aaaaggaatc atcaatctgc acttctttat gtggtttgtc
    20941 cactatgcgc tttatgctct tattccattc tttgccgttt tatttggagc agatgttgtc
    21001 aaaagcgtct tggataatat tccagaggtc atcatgaacg gattaacagt cgctggaaat
    21061 ctgctgccgg cagttgggat ggcgatgctg ttacggatgc tttggagtaa aaatattgct
    21121 gtgtggtttt tctttggggc cgttgttatg gcgtatctcg agttaccatt gattgcaatt
    21181 gccgcagttg gaacgattat tgcaattgtt atagcccaaa gagatctaca actaaaaaat
    21241 atatctgttc atgcagttca aagcgatgct gctgtaaatg caacgcttga ccaagaagag
    21301 gaggatttct ttcaatgaaa ttagctgatg gaatttctaa agatgagaaa aaattggttc
    21361 ggaagatgtt ttggcgctcg atgactatgt atgcttcggt gaatccggtg acgatgggcg
    21421 gcggtggttt cgcctattct atgatgccct tcattaatca tttctacaaa agtgaagaag
    21481 atcgagctgc ggcgctggaa cgtcatacac agtatttttc gacgaccatt ccttgcgcgt
    21541 cctttgtcat ggggattgcg gcatcgatgg agaaggaaaa ttctgaaaaa gctggttttg
    21601 acgtggaaag tatcaacgcg atcaaaacga gtttgatggg accattggct ggaattggcg
    21661 attcattgtt ctggggagtt tggcgtgtcg ttaccgcggg actagcgatc aacttagcca
    21721 atgccggaaa tattttggca ccaattatct ttttagttat gttcaatata cctaattact
    21781 tgatgcgata ctatggcggc gttttaggct attcattagg ctctaaatat attgaaaagc
    21841 tgtatgcgaa cgggttaatt gaaattctga caaaagctgc tagtatcttg ggtctgatca
    21901 tggtaggtgc aatgacgatc agtatggtca aattcaatac cgttttgagc ttttcaatga
    21961 agggcgaaga actaatgaat gtccaagaaa tcctcgatag tatttttaaa ggaattgtac
    22021 cgttattggt aacattgagc tgtttcaaat tactagataa aaaagtcggc gtcatcaaaa
    22081 ttatttttgg aatggtcgtc ttgggaattt tattgtcatt acttggaatc gcatagtagg
    22141 aagctgcagc tactaggctg cagttttttt agcaaggagg gaaaagatga ctattaatga
    22201 agtaatttat tcacccaaac acccattttt taatgctgag ttaaacgacg gaaatgtgac
    22261 tacttcaaac gaatacagct actatcggaa tattcctgat gtaaagggat tgaccttcga
    22321 tgtaagtaat caaaagacat tagcaaacct tgatgtttgc gggacgattc aaacgttgac
    22381 cttttatcga gaaaatttac taactgagga aaaaccaggt gtttgggtca ataaacagct
    22441 ctctcaaacc aattcgttat ccttaaaggt tgaagtaaac gggattgtct accatttgtc
    22501 agaatcggat catcgtattg aagtcgatgt gattcaagac tgtttgccta gatatattca
    22561 tcattattcg acgtttaagg tcattgtagt atcctttgct cccatactgg ctaataagcg
    22621 tttaagtatg cttgttcaac aggtttacat tgtgaatgaa acacacgaaa gccttcaagt
    22681 ttcagtgaaa gatgtgcctt cgtatcaaga gaagtattcg gatcagcaaa atgtgttgat
    22741 ttctcaaaaa ggaaataagg acacgatcgc acaacaggaa gtggcaagct tcgccattgc
    22801 ttttgtggac ccaaatgctt ttgaagaagt aatgactttt caggaatctg atatcgaaaa
    22861 atggctgaag gaaacattga actattttgc tcagctattt gggcagctgt caatgccaaa
    22921 cgatagagtt gtccatctct atcgtcgtgc actttatcaa agcttttcta gtttcggtat
    22981 gaatcgacag ggacaggtcg tcggcagcaa ttggggcagc tatcctgcta ctaatcgaat
    23041 ttggaataag gatatgtatt acgcatcatt gccattcacc atgtttgaac cggagttatg
    23101 tcaaaaaacg gttctatggt ttgatcaata tggcgttaag tttcctggtt caaaatttac
    23161 aggaggtatc aatcattctc tgagtaattc gttatccagt gcgttactgg ctagtcttta
    23221 ttttgaacat actggggata caaaattctt tgagcggtgt ccgcaggttc tactgaatgc
    23281 ttcaagaatt attgaggaca tattagctca acgtcggtca ggggaaccaa tgctttttcc
    23341 atctgtttgg ttatcagacg cctttgcact tggaaagtat cataccggca gcaatctttg
    23401 tctttggaag gcctgtattg gacttgcaga aatttttgaa gccctagaac aactgagtct
    23461 tagcaagcga tacaaaaaca ttgcctgtaa actaaaggaa tcaatttgta aacaaatgac
    23521 tatcgatggt ccttttggtg agcaattttt ggagggaatc ggtgatgagg agaaaacaac
    23581 ctattcagtg aagcactatc aaaaaccgat tcttgagcaa gggttaatct ttttaagtga
    23641 tgtgattgtg gatggaaaaa ttaatttatt gatgcatgat ggagaagaat cagacactac
    23701 gttgatgcct ttttatcaat ttttagataa taaagatcat ttatatcaga acaccatggc
    23761 cttttctgct agttctttca atccaaccta tagcgaggaa atcaaaggca tcacttgggg
    23821 attagaatcc ggcgccactt ttcctggctt tatcactgtt ttaatgagcg agctgcacaa
    23881 ccctcaagct ttcgtaaccc gattagaaga actaatttgt ttggcagatt tagacggttc
    23941 gtggtggtgg tggccgtatc gcttagaggc tcaacaagga gaagtcgtgc gagactttgg
    24001 ctgcggcaaa tgcggctggg catcgggtct ttttgtcagc ctaatgatca gtcaatattt
    24061 cggattgaaa ttcaaaaaag gagtattgca aattgatcct gttgataatt taacgttttc
    24121 ttggaagaat ttgaagttcg gtcaagcctt catttcgatt gaatgtacgc aatccgagtt
    24181 gagtatttca aatttgtcag aaaagccatt gaaaataagt gatacgaaaa aaattcttca
    24241 cgtagaaaag ggaaaaacga ttcacattca aaggagaaaa agatgagtat actaaaaaat
    24301 attacccaat ttaaaaaaat ccagagtcga gcaatcactc ccgaaaatcc aacaggcgag
    24361 aaaggtaaag ctgcgatgtt gccaagcgag ctaggaccaa gccgcaaagg tcgtggcgca
    24421 attccgctga cttctggtga agaaactgtg attgcggata ttactggaac gggaataatt
    24481 cgtcatatgt ggatgacgat tcgtgatcga acagaatttg gcagttttgt tttacgtgat
    24541 ttaatcttaa gaatttattg ggatgggtcg gatagccctg ctgttgaaag tcctttaggg
    24601 gatttctttt gtaatgggtt tggagagcgt tgcgaggtga actcgttgcc gatagtggtt
    24661 aatcctacag ggggctttaa ttcctatttc gaaatgcctt tccaaacatc cgctaaaatt
    24721 acgatcgaga atttacatcc gaaggatatg tcctcatttt tttatacgat aaattacgct
    24781 ttggtggacg aattggaaga aaatagccta tattttcacg caaattggca tcgggaacgc
    24841 attaccaaat tacaggagga ttataagtta attgatcgat taaagggtca aggctattac
    24901 gtgggtactt accttgcgct tacctgccta gaacgttatt ggtggggcga aggcgagttt
    24961 aaattctaca ttgatgggga tagtgagtat ccgaccgtaa cctcaacagg ttcagaagat
    25021 tattttggcg gggcgtgggc ctttcatgag tacgatgagt tcggacgtcc acatgcgaaa
    25081 aactattcaa cagccttttt agggtatcct taccaatcaa atagagatgc cacaagagat
    25141 cgttttgaaa cgggaaaatt gaatgccgtt catgcctttg gtgacgacgc aatgccacga
    25201 catggtcttt atcgttggca tcttcaagac cccatctgtt ttaccgaaga tttatcggtc
    25261 actttacaac aaatcggcaa cgatgatgtt cgcttatttg agcggcaaga cgatgttgct
    25321 agtgtcgctt actggtattc aacagaagct tcaggaaata ctaaacgtca tttcactgat
    25381 cgagaacgct tgccgcgtta atgaagtgtt tttcacatat tcgaagggag gaacctatga
    25441 tgatatatgg ggcaattgaa gctggaggga ctaaatttgt ctgtgcagtc ggtactgagg
    25501 aattaacgat tttggaaaga gtcagttttc ccacaacaac tccagttgaa acaatgaagc
    25561 aggtcattga tttttttaaa ccttttaagg aacaattggc aggcatcggg gtcggctgct
    25621 ttggtccaat tgatattcaa tgcaaatcaa cgagtttcgg tcatatcaca tcaacaccaa
    25681 aacttgcttg gcaaaatttc aattttgtag gaacgctaaa gcaatatttc aatattccga
    25741 ttgaatggac aacagatgtc aatgcggctt gctatggtga atatgttgct ggttctggca
    25801 aagggttagc aggtgttgca tacttcactg tgggaacagg tatcggaggt ggtgccttgt
    25861 tcaatgggac tttcgtggaa gggttcagtc atccggaaat ggggcatatg ttgatcaagc
    25921 gacatccaaa ggacaatttt tcaggaaact gtcccttcca ccaagattgt ttagagggga
    25981 tggcagcagg accagcgatt gaaaaacggt tgggtgtaaa aggccagaat ttattggctg
    26041 acgattcgtt ttggcagatt gaagcctttt accttgccca atgtgcatac aatacaacac
    26101 tgatgttttc gccagataga attatttttg gcggtggtgt aatgaaacaa gaacacatga
    26161 agaaaaaagt tcaggataaa tttgttgagc ttataaatgg atatgttgaa ataccaccaa
    26221 ttgatagcta cattattacg cccgaattag gtgataatgc cggaataatc ggcggattag
    26281 cattggccag aaaagcggta agaaataagc aaccataatt aatgaatgtt tcattgatac
    26341 tcatgtcaaa agtatttaac cgagtaatca aatgatcaaa tgaagttgga taaagcgaaa
    26401 atgaattcaa ataaaaaggc tctaagtcaa atcgtgttgt tttcattaaa tcactgaaag
    26461 gaaatgcttc tgcgtttcct tttttctttt tgttgtgcgc tgtatacctt gaggatattc
    26521 actggtggcg tacacttaaa tagtaatata ttgtgttact ttatgtctgt ggtaatagtt
    26581 atagttgctt accaatgtat gttcattttt cgaaatgttg acttcataat ccttggctta
    26641 atgtttgaat ttttttggtg atagattttt tcagccg
//
LOCUS       DAXLPC010000032        26171 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.032, whole genome shotgun sequence.
ACCESSION   DAXLPC010000032 DAXLPC010000000
VERSION     DAXLPC010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26171
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.032"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..416
                     /locus_tag="ACF3UE_001305"
     CDS             <1..416
                     /locus_tag="ACF3UE_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3634728.1"
                     /translation="VCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLVLWEKKKTSV
                     KELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAALQKQAEGIP
                     QKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            525..1604
                     /locus_tag="ACF3UE_001306"
     CDS             525..1604
                     /locus_tag="ACF3UE_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3634729.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(1730..3019)
                     /locus_tag="ACF3UE_001307"
     CDS             complement(1730..3019)
                     /locus_tag="ACF3UE_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3634730.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEVAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKLEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            3167..4720
                     /locus_tag="ACF3UE_001308"
     CDS             3167..4720
                     /locus_tag="ACF3UE_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3634731.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            complement(4828..5910)
                     /gene="uxuA"
                     /locus_tag="ACF3UE_001309"
     CDS             complement(4828..5910)
                     /gene="uxuA"
                     /locus_tag="ACF3UE_001309"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFD3634732.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(5901..7547)
                     /locus_tag="ACF3UE_001310"
     CDS             complement(5901..7547)
                     /locus_tag="ACF3UE_001310"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFD3634733.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            7731..8393
                     /locus_tag="ACF3UE_001311"
     CDS             7731..8393
                     /locus_tag="ACF3UE_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3634734.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8537..9100
                     /gene="ahpC"
                     /locus_tag="ACF3UE_001312"
     CDS             8537..9100
                     /gene="ahpC"
                     /locus_tag="ACF3UE_001312"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFD3634735.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            9110..10639
                     /gene="ahpF"
                     /locus_tag="ACF3UE_001313"
     CDS             9110..10639
                     /gene="ahpF"
                     /locus_tag="ACF3UE_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFD3634736.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            10796..11146
                     /locus_tag="ACF3UE_001314"
     CDS             10796..11146
                     /locus_tag="ACF3UE_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFD3634737.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            11245..11775
                     /locus_tag="ACF3UE_001315"
     CDS             11245..11775
                     /locus_tag="ACF3UE_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFD3634738.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            11929..13080
                     /locus_tag="ACF3UE_001316"
     CDS             11929..13080
                     /locus_tag="ACF3UE_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFD3634739.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(13189..15228)
                     /locus_tag="ACF3UE_001317"
     CDS             complement(13189..15228)
                     /locus_tag="ACF3UE_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFD3634740.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIPDKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(15286..15843)
                     /locus_tag="ACF3UE_001318"
                     /pseudo
     CDS             complement(15286..15843)
                     /locus_tag="ACF3UE_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     regulatory      complement(15991..16157)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            complement(16382..16588)
                     /locus_tag="ACF3UE_001319"
     CDS             complement(16382..16588)
                     /locus_tag="ACF3UE_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634741.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(16604..17218)
                     /locus_tag="ACF3UE_001320"
     CDS             complement(16604..17218)
                     /locus_tag="ACF3UE_001320"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFD3634742.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(17365..18048)
                     /locus_tag="ACF3UE_001321"
     CDS             complement(17365..18048)
                     /locus_tag="ACF3UE_001321"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFD3634743.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(18157..18615)
                     /locus_tag="ACF3UE_001322"
     CDS             complement(18157..18615)
                     /locus_tag="ACF3UE_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFD3634744.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(18699..20462)
                     /locus_tag="ACF3UE_001323"
     CDS             complement(18699..20462)
                     /locus_tag="ACF3UE_001323"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFD3634745.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(20683..22143)
                     /locus_tag="ACF3UE_001324"
     CDS             complement(20683..22143)
                     /locus_tag="ACF3UE_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634746.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(22351..23277)
                     /gene="glsA"
                     /locus_tag="ACF3UE_001325"
     CDS             complement(22351..23277)
                     /gene="glsA"
                     /locus_tag="ACF3UE_001325"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFD3634747.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(23300..24727)
                     /locus_tag="ACF3UE_001326"
     CDS             complement(23300..24727)
                     /locus_tag="ACF3UE_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3634748.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(24758..25972)
                     /locus_tag="ACF3UE_001327"
     CDS             complement(24758..25972)
                     /locus_tag="ACF3UE_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFD3634749.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         7615 a         5043 c         4626 g         8887 t
ORIGIN      
        1 aagtatgttt tcctttatat gccgcctcta aggaaatcat tagacactac acttccctcc
       61 tcaagccgct gaatcttacc tatacccagt atcttgtgat gttagtttta tgggaaaaga
      121 aaaagacttc agtgaaagag ctaggaaatg atttgtgtct ggattctggt acgctgactc
      181 ccttactaaa aaagttagca gaaaaaaatt atattaatcg tcagcgtgaa acgggtgatg
      241 aaagaatcgt aaatgttacg ctgactcctc aaggtgctgc gttgcaaaaa caagcagaag
      301 gtattccaca aaagatcaag tcttatcttc cacttgaaca ggaagaattg gatacactgc
      361 aacatctgac ccgaaaaatg ctagataatt ttcatcaaga ccagaaaaag ggctgaaact
      421 gctagatgaa cgattttatg aggaaaacca actcataaga taacgtcatt tagcggtttt
      481 tctttttgct ctttctcttt cttattttca tattccatca tataatgaat aacgtgttta
      541 ttttttgtta tttggaggtt gtcgatttga ccgtttatca gcgttttttg gcgaatgaaa
      601 aaatacgccg tctcactgtt ttattatttg tcgtttttgt tcttttctta gttagaagta
      661 tgattacaac cattttgctc acatttatct ttacttattt gatgattcat cttgttcaaa
      721 tcattcagcg atttgtccga atccctacag gtgttttagc tatcatgatt tatacactga
      781 tcgtttacct tatctatctg gcattcacaa agtatatccc gatgcttatt catcaaacat
      841 ttgatatgat ccagtccgtt attgattttt acgagcatca gccaaaagat gcagatcctg
      901 ttttacaata tatccatact tatattgagc gaaacgattt ttttgaacag cttcaaaatg
      961 gcgcttcgat tgcgcttggc tatttacagg atataggaaa aatggcagtg gcgtttgcta
     1021 tgtcattcat cttaagtttc ttttttatga ttgaaaagaa aaaaacaatt gtattctcaa
     1081 gattgttttt aaaaagtgaa ttttcttggt tctttcaaga tatttactat tttgccgata
     1141 agtttgtcaa tacatttggt ttggtattag aagctcaatt tgttatcgct cttttaaaca
     1201 cgttgctcac tacaatcgcc ttggctgtat ttggctttca tcagctgctg agtttagcga
     1261 tcatgatttt cattttaagt ctgatcccag tagcaggtgt tatcatttct tgtattcctc
     1321 tatctttcat agcttattcc caaggaggca tccgagatgt tgtttatatc ctgattacga
     1381 ttttgattgt ccatctaatt gagtcttatg tgctgaatcc gaagttgatg tccagcaaaa
     1441 cagaactgcc gattttttat acatttgtgg tcttacttgt tagcgaacgg ttctttggcg
     1501 tttggggctt gattgtcggc attccgatct ttaccttctt tttagatgta ttgaaagtga
     1561 aaaagatccc gaaccatctt ccaaaagaaa cagatatccc ttaaaataaa tatgaagaaa
     1621 gataaagtat gaacgacccc aaatatcaga tttcaatctg gtattttggg gtcgttttct
     1681 ggatatttct ttttatttga aaaatgcgtt cacagacatt attcaaatgt tagagagatc
     1741 tgttttgttt aaatcttttt gcagaaagca ttgttgctat acttaataga atgattccgc
     1801 tccacagtat aactttgttt tgtgactctc cggattttgg tagctgttta tttttcgttt
     1861 caggactagc aaaggttgta tccttgctac tttttaaggt ttcagctgat tgggcgctat
     1921 caaatattcg tgatttttta ttcagctgct cttcatttat ttttagaatt gctagatttg
     1981 attttttact ctcttttttt ccatcctctt gaattgtttt tttgtttatt ttttctggta
     2041 ttccttggtc tcttgcgtcc gtatctggtt ctggagtcac atctggtttt tcttctggat
     2101 ctacctctag tttttctgga ttttcagttt cattatctgt gtctggattt gtttccggta
     2161 ctgtttggtt tccagaatcc gtatctggtt ctggagttac atctggtttt tcttctgggg
     2221 ctacctctgg tttttctgga ttttcagttt cattatctgt gtctggattt gtttccggta
     2281 ctgtttggtt tccagaatcc gtatctggtt ctggagtcac atccggtttt tcttctgggt
     2341 ctacatctgg tttttctcca ggggttattt caggttttga ttcattgtct ggctctggtt
     2401 gagtttctgt atcgggttct tctccaggtt ctatttccgg tttctgttct ccgtctggat
     2461 tttctgtagg cggtacttct ggcttatttt cattttctgg tttatctgtt ggttcttcaa
     2521 caagatctcc tcctgagtcg atagctgaat cttgctcaat tgtctgccgc tgactatacg
     2581 gcgttaaatg atgatgatcg ttcggtagtc catctgatac cttgacagta aaaagcgctg
     2641 gttttaacaa gtcctgattt aatgtaacgg tgaaggtaaa tatcgcttgc ttgtgttgga
     2701 tagtcaaagt gttctcgtca tagccaatcg acaaagcggg atcaacattc tcaaatgtaa
     2761 cagctgattg tagtataggt gctaagtctc ctgaatagtc aatttttgct ttgatggtcg
     2821 ctgtttgtcc ttttcttaat tttgcgactc ctgaattgaa ggatgaaaat tcatcctgaa
     2881 aggtaattcg attgacgttg gcccacttgg tttctgtcca tttggctgtt tctatctcct
     2941 ctgtgtggac tgtctgattt atagtaagcg ataagcttaa ggctgcaaat gttgatatta
     3001 agatggttga atatctcata actctctcac tccttgattt ttttgtatgc aagaaataag
     3061 atagtagaga ttctacctat atgtttactg tttttttgtc taaatttatg aaaaaaacag
     3121 taatattttc aagttttaac aatttaagta aaaaggagcc tctttcatgc aaactcaaga
     3181 agcgattaaa acgtttctct tgaagaaaaa aagcaataca aaattagata tttttctttt
     3241 cctatctgaa catcgtttct ttattactac acaatattta gcagatcatt tccatatgtc
     3301 tgaatcaaat tttttactat acatcaaaga attagaacaa gactttgagc gtctcaatct
     3361 aacagaactg catattgata agcaaaaacc ttttttaaag ttgaattttg aaggaattga
     3421 tccggcttac tgctattatc gtctatttgg aagatactgc aacgaatcag tcagttatca
     3481 gatcttgact tctttgttca gctgtcagac aaattcgatt atcagtttaa gtcagcaaac
     3541 aaactatagt gcctcttatt tgtatacgaa aatgaaaaag attaatgcat ttttagcatt
     3601 gtacggtttg tctatctcct tttctaataa tggcagaaag tctttttctg gaaaagaggt
     3661 acaaattcaa tatgcagcat tagatattta ttggaacatc ttttcaagta ctgctacaga
     3721 attttatgat gaagatccgc aagtagtggc ttttatgatg aatacttttt ttaaaaaaga
     3781 agtacttgac cgactaaata gcggtatgat agataaatta tattttctat taaaaatatg
     3841 taaagagaat tttcctgcaa cttctgtgaa agacgtacaa aaagaattca cagagtatga
     3901 atatattgac ttttttattg atccctctgt agatattttg cgacctaatc tgccaatttg
     3961 tcgcgaacaa cgcatcttag tgaatatttt agctcgactt tctatcacga aaatcgaatc
     4021 ggaagaaaca agcttggagc aatacaaact tttaaaaaaa gcaaacgttc ctcatgttct
     4081 ttattcaaga gaaatggtgg agtccttttg tactgtattt gatttgttta tacctgaaaa
     4141 agaaaagatt ctttactcat tggcattcgc acgaaataaa ctttataatg gatttcttaa
     4201 cttcaatcaa ccaaatacgc cccttcctac tttcatgctt tatcaagaac atagcgtgtt
     4261 gaaagaagtc caaaccgcca ttgaacaatt ttatatggat ttcagagaac aaaatcaaca
     4321 cttgttacca gttattttag aaaaggaaaa tgtgcaatgg atggttgaag acctagtaca
     4381 tttgtatgat cgctacaaaa aacagccgcg aattgtgatt ggtgtgaact atacgcgtga
     4441 tttttatatc agtaaagatc tgatcgttaa gatagaacaa attttttcaa atgaatcgat
     4501 caaaatacaa aatgatttta tggagaactg caacatcgtt atcagcgact gccctttgaa
     4561 acaattgcct tctcatatca aaaaaatcta tattttaaaa ggaatcatca caccagaaga
     4621 ctggaaaaaa gtgattatga ggatctcaga atatatcttt gaattaaaag aagaagcact
     4681 catggatcaa tcgaaaaaag aaaatcaagt tacttcctag accaaataag atacataaat
     4741 ccgaatgctt attaacaacc tccggattta tgtatcaaga atttgaacat ccttcttatt
     4801 tacataataa aattacagtt tttttcacta attatcttta cttttgtttc ctttttcgat
     4861 tgcttcccat aatccattta gataaacagc acctaatgct cgatcatata agccgtatcc
     4921 tggtcttcct gtctcattcc agatcattct tccatgatca ggacggatgt atccgttaaa
     4981 tccgttgtca tacattgttt ttagtatgcg gtacatgtct aatgaaccgt attcggattt
     5041 atgcggtgcc tcatagaaat ctcgattagc taaaaattta atatttcgaa catgtgcaaa
     5101 tgggattcga tctctttgac aaaattctgc taaaatccca tatacatcat tttctggatc
     5161 ttctgcaata ctccctgtac aaagagtgat tccgttataa gggctgtcta ctatgcggca
     5221 caaccaatct aaatcttctc gattctttac gattcgaggt aatccaaaaa tcgagtatgg
     5281 cggatcatct ggatgtacag ccattttgac ccctacctct tcacatgttg ggatgattga
     5341 ttggagaaaa taggcaaaat tttctcgaag tttttcttcg tctactgatg cataggcttc
     5401 aagcaaggat ttgatatgag ctaagcgctc aggttcccat cccggcaatt caaattcatt
     5461 gctggaatgt tcgatgcgcg cgacgatttc tcttggatca tctggaatat catcagatat
     5521 aaaagctaac gtggatgagc cgtcttctaa gcggtagtca aggtcagatt tcacccagtc
     5581 aaatacaggc ataaaattat agcagatgac ttctattcca tattctgcca agtttcggat
     5641 tgtctgctta tagttttcga tatactgctc acgggaaggt aatccaattt taatggcatc
     5701 atgcacattg acgctttcaa ttacttttag tgttaaccca cgagactcaa tttcttcttt
     5761 tagttctttg atcctctccc taggccatac ctctcctact ggtatatcca tcaatgtgcc
     5821 tacaatccct ttgaccgcag gaatctgtct gatttcatct aaggtaatct tttcttcctg
     5881 tgatccgtac catctaaaag tcatttccat gataaatttc ctccatgttc ttgtaagtaa
     5941 tcctgtaatg tttttcgtac ggcattcggt cctgctacca tcttgatgaa catttcttct
     6001 atttttctgc caagctctgc ttggtaaaga tctacaccaa aaatttcttt atttgacaaa
     6061 ataggagcca ttttctcatg aatatgtgat gtatcttgcg tacccagttg aatatcggaa
     6121 agcttatgct gaaagtctgt caatagtggg tctggactcg ggatgaatgg ttttccttga
     6181 tcatcaatgc caataaggta tcgaagccaa gcagcgagag tcaatggtat gaatacaagt
     6241 gtctgcgggt ctttaacttc tatttccata tattttttaa tcgtctcacc ataacgaatc
     6301 gccacctttt gagaggtatc cgtggcgatt cgctgaggca tatcaggaat atttggatta
     6361 gaaaagcgca cagtaattac ttcttccaga aagatctttg gatcaatgat acctggagac
     6421 tccacaactg ggaggccttc attgtacccg atttcagaaa ctagcagcga taaatctgga
     6481 tctttcatct cctcagctat gctcctatac cccagtaaac aacccataat agctaaagac
     6541 gtatgcaaag gattaaggca agtcgtcacc ttcatcgtat ctgctttatc taccgttgca
     6601 cgatcagtca agaatacccc agctttttcg aatttcggac gtccattggg aaaatgatct
     6661 tccatgatta aataatggat gtcctctgta ttgacaaatg gagcaatatt atttcctttt
     6721 gcggtttgga aaatcgacat atttgaaaag ccctcttttg ccaacatttt gctaactgac
     6781 aaggaaggat tcggggtgat acgatcaatc atcgtccatg gaaacgcaac aatttcttca
     6841 ttcgataagt attggataaa tgtattttgt acataacctt ccttttgcca ttcttttgcg
     6901 atcgttagca aagaagtacg taattgacta ccgttttgtg aaaaattatc tgtagagaca
     6961 agtgcaatcg gccaagctcc agataaaaaa cgtttataaa gtagcgcagc aagaatactc
     7021 attgtatgtg atggcttctt tggaccattt tttatatcga ctgcaatcgg tcctatatat
     7081 ttattatttg tatctttcaa tcgataacct ttttcagtaa tagcaaaagt aactaattgt
     7141 aaactaggat tttcaaagtg tcgaatcatc ttatcaaagt gttcagaaca atctggatga
     7201 caatacagac tgtcagctgt cgcagctaat atacgtttga cgaactctcc actgcttggc
     7261 atgaccactt caagaatcaa atcatcaaaa tcttggtaag ccctttcaat tatttcttca
     7321 tcgaatgttt cacaaacaat gacaccagtg gacaattcgc ctagatccgc taaacgttga
     7381 gcgatttctg catgaaatcc tcgataaaga tttccgccac cgaaatggat ccagacagga
     7441 tttttttgtc cattttctct taatgatgca cggtcaaaat gaggtatttc tacttctttt
     7501 tgagataatt cagggataaa gttcctccag ttgtttaaat caatcatttt tcccctccta
     7561 aactaacata ttagtttttg tattcaagtg aattttatac aataaaaatc gctatgtcaa
     7621 ccaaaatttt actatttata caaatttact agttaatgtg acataccaga ttgtttttca
     7681 gacctcttct gttatactac gttcatagaa atgattttgg aggaataaag atgaaaagca
     7741 gcttgcaatc acaagcttat caagcgattc gtaaacaaat tatctatgct gacttagaac
     7801 ctggaaggaa aatatctgaa aaggcactgg aggaacatct tgctatcggc cggactccca
     7861 ttcgcgaagc attgattcaa ctacgtcagc aagaactcgt gtatacgata cctcaaagtg
     7921 gtacgtatgt ttccaaaatt aatcttgttt ctgcagaaaa tgctcgcttt gtccgagaac
     7981 agttggaaga gcaaatcatg attgaatgtt gttccaaatt ggacacacaa acacgaatag
     8041 tgctagaaac gattttagaa gaacaagaaa aagcagtcaa aataaatgac gaacgcgctt
     8101 ttttccgtgc agataattta tttcatgaag cttgtttcga aattgcagga agaaaagaag
     8161 tttggaactg gttagatgac cataataccc atttagaacg tttccgctgg ttacgagtga
     8221 ccattcaggg gcttccatgg gaaacgatca tggaacaaca ttatgattta ctcaaggctt
     8281 tagttgataa aaaaccagaa gaagctcgat ttcaaacggg attgcactta cacatgatgc
     8341 tgaaagaaca ggaaactgtt actcaacgtt atcccgagta tttccagcag tagcattttc
     8401 ttgcgacctc ttctattttt ataattaacc ttcgtttttg agtaatcttt attaaataac
     8461 aaaatatcca ttgactttgc aactccaact aaattacaat aattataaat aaataattat
     8521 tattggaggt tttactatgt cattgattgg gaaaaaaatc gaagaattta atgcacatgc
     8581 ttatcatcaa ggagaatttt tagaagtcag tgaaaaagat cttatgggga actggagtat
     8641 tctttgcttc tatccagctg attttacttt tgtttgtcct actgaattag aagacttaca
     8701 agaacaatac agtacattga aatctttagg tgttgaagtc ttttcttgct ctaccgatac
     8761 ccactttact cacaaagcat ggcatgatac atcagatgct atcggtaaaa tcgaatacgt
     8821 gatgatcggt gatccgtctc atcagatttc tcgtattttt gatgttttgg atgaagagca
     8881 aggattagct cagcgaggaa catttattat tgatccagac ggaatcgttc aagctatgga
     8941 aatcaatgca gatggaatcg gtcgtgacgc tagtgcactg attgataaga ttcgcgctgc
     9001 tcaatatgta cgtacccacc caggtgaagt ttgtccggca aaatggaaag aaagtggcga
     9061 aacattgaaa ccaagttttg atcttgttgg aaagatttag gtggtggata tgttagacaa
     9121 agaaactaaa caaaatctcg aacaatattt agcactgatt gaatctccta ttgttttttc
     9181 tgttagtttg gataatagtg aaaatagtca aaaactagct gaatttacga aggaaatagc
     9241 agaaatgtct cctaaaatct cttgggaaaa aagagattcg atgcgcacac ctagtttttc
     9301 tatcaatcca gttggcaaag aaagtggaat cgtttttgct ggtatccccc tcggtcatga
     9361 attttcctct tttttactgg ctatgttaca aattagtgga cgggcaccga aaatcagtga
     9421 atctttgagt cttaaaatca aaaaaataac acaaacattg cattttgaca gttatgttag
     9481 cttgacttgt cataattgcc ccgacgttgt acaggcattg aatatattag ctgtattaaa
     9541 tccaaatatt actcatacga tgattgaagg tgggatgttc caaaaagaaa tcgatgataa
     9601 aaaaatcatg gcagtgccaa ctgtgttttt aaatggagaa gaatttagta gcggacgcat
     9661 gacgatcgaa caaattgttg aaaaaatcac tggccctttg attgaagaag agttgtttga
     9721 aaaagaacct tatgatgtat tagtaattgg cggtggacca gcagctagta gtgcagctat
     9781 ctatgcagca cgtaaaggaa tccgtacagg acttgtcgct gattctttcg gcggacaagt
     9841 cgttgaaaca ctagggattg aaaatatgat tggtacctct tacacagaag gtccaaaatt
     9901 gatgcagcaa gtagaaagtc atgtgcgtag ttaccctatc gacattatga tgaatcaaca
     9961 ggccgtttcc ttaaataaag agcaacattt tattaatatt ggcttagcta acggtatatc
    10021 acttaaagca aaaaccgcca tcatcgcgac aggtgcgcac tggcgttcta tcaatgtacc
    10081 aggcgaaaaa gagtttaaaa ataaaggaat tgcttattgc ccacactgtg acggcccttt
    10141 atttaaagga aaagagattg ctgttatcgg tggtggtaat tctggtgttg aagcagcaat
    10201 cgatttggct gggttagcaa aacatgtata tgttctagaa ttcttaccag aattaaaagc
    10261 agatcaaatc ttacaggata aactagtctc tcttgcgaat gtcactgtta tcaaacatgc
    10321 agcgacgaaa gaaatcagcg gtacgaatca ggtagaatct ctctcctata tcgatcgccg
    10381 tacgatggag atgcatacac tagctgtttc aggagtattc attctagtcg gcttactccc
    10441 taatacggat tggctagatg gaacgatcga aatgaatcca agaaatgaaa tagtgaccga
    10501 gaaaaatggc gcaacgaata tccccggcgt tttcgcagct ggtgattgta cagatagtcc
    10561 atacaaacaa atcattgttt caatgggttc aggagctact gcagctttag gagcattcga
    10621 ttatctgatg cgcacttgag ctatgaagat tgtaaaaagt cagagagcgg aaaaaaggat
    10681 ggtgacaaga attttgtcac aatccttttt gtttttttga ataatcgctt tttcttctct
    10741 ttttcttata tactataagt agtaaataat ttgaaaaaaa gaaaggtgac tgattatggc
    10801 gcaaaatcgt atttttacga caagttttgc aagcgtttat cctatgtatg tagcaaaagc
    10861 ggagagaaaa gatcgtataa aagaggaagt agatgaaatc atttgttggc tgacgggtta
    10921 ttcccaaaca gaactagaat atcaactaca aaaacaagtg actttcgaac aattttttgc
    10981 ggaagcccct gtccccaatc cttcacgttc cttgattaca ggtgttgttt gtggtgtacg
    11041 agtagaagac atcgaggata acttgatgaa agaaattcgt tatttagata aaatgatcga
    11101 tgagctagca aaaggcaaaa aaatggaaaa gatcctcaga agttgatttt tccagagata
    11161 ttcttctcct tcgctcattt tgtaacattt aatttggtaa aatgactagt tcacgttaaa
    11221 ataagtcaaa ggaggttttc ttatatgttt gagacgatta aacaaaatat tcaaaaatac
    11281 gccttattaa gagctgctgt ttatattatt tctgggattg cgattgtgct aaacccttct
    11341 gctgtttttc attttatcgg ttatctgatc accgcctatc ttgttttgct tgggttgttg
    11401 aatctttttg aggcttaccg ttttaaaagg aaaacaggtt cttggagtat cggtctgttc
    11461 agtggtcttt ttttcctgat cttagctctg atcgtctatg cttttgcacc tgcaatcgtt
    11521 tctatcctgc cgattcttct tggattagct gttatcatca acagcttgtt ccagttgttc
    11581 ttcagcatga atacaaaagc taaaagttgg agtgtttata gtagtattct gttgttgatt
    11641 ggcggattcg tcttattgtt caatccattc aaaagtttga tgcttctatt ccaaatattc
    11701 ggctttattt tgattttcat gggcatccag gagattatca atttcatcag aataagaaaa
    11761 atgactatac gttaatcatt tttagttatt aaaatagacc gtataaaaac caacaatcca
    11821 aaaaaatctt ttggattgtt ggtttttttg tgagtatatt ttcctatttt ttcaataatg
    11881 tatgttatgc taagttcggg ctatatttta tacaaaggaa tgatgagaat ggaatttatt
    11941 ggtattttat gcctgatatt gatttcaaca acgattggct cacatatctc gcggagatta
    12001 ggtatcccag cagtgattgg acaattactt gttggtgttt tgctaggcca agctggattg
    12061 aattgggtca aacctgatat tctagtccat gacttttcgg agattggtgt gatcttatta
    12121 atgtttttag ctggtctgga aagtgattta tctcttttga aaaaatattt ccgacctggt
    12181 atgttcgttg ctttgcttgg gatcatcttc ccggttgttt ttggctggtt gacaggcaaa
    12241 gcattccaag tttcgggaaa tgaagcgatt ttctttggga ttattcttgc ggcaacttct
    12301 gtcagtattt cagtagaagt attaaaagaa ctaaacgtag tgaatacaaa agaaggatca
    12361 acaattttgg gtgcttctgt ggtagatgac attttagtcg ttttagttct aagtttcagc
    12421 ctatcttttc taacggggga agcttctagc aatgcttctt taccgcttgt tttgattgaa
    12481 cagctaattt attttgtttt tattttctta ttagtcaaat ggattgcgcc tttcctactt
    12541 tcatttgcag aaaaagtgta cgcaaattct tctattatca tcgtatcgct agttatttgt
    12601 ttaggaatgt cttacgtagc ggatcttgtt gggcttagct ctgtcattgg tgcttttttt
    12661 gctgggatag ctgtcagtca gacaaaggtt aaagaagaag tataccacaa tgtagaggct
    12721 ttaggatatg cagtatttat accagtattt tttgtcagtg taggattaga agttgatttt
    12781 tctgacttta gtgaacaact actctttatt tctatattga cgcttgtagc gattttgacc
    12841 aaattgcttg gaggttattt tggtgctcag attgccggtt tttctcaaca tagttcattg
    12901 atggtcggtg ctggtatgat ttcgcgtgga gaaatggctt tgatcatttt acaaattgga
    12961 cagcaaagtc aattgatcga accacagtac tattcacctt tagttatcgt gattttatta
    13021 agtacactta tttctccact tgttctcaaa tattttacaa aaaaagttta tgaagtgtga
    13081 gtaaatcaaa aagaagttgt gaaagagaca tcgtgaaaac cgtttatttg aaaaaaggac
    13141 tgtgacgata acgccacagt ccttttactg tacttaaaaa gcaatttttt attgataatt
    13201 ttggttgagg tattgcaata gttccgatgc tcgtttggtt gctgaatcat catcttcttt
    13261 attttccaac atgctgacca tcatataacc ttggttatca agattgaaag caaacaagaa
    13321 actgttctct tgccccttta catcctgttt ttctttgatt tccgctgtac cagttttcgc
    13381 tgccaacgga atccctaaag cagaaagaga atgtgctgta ccatttacat cttgcacaac
    13441 ttctctcaga tctggcacga tcgtttgtac tgctgtttcg ctgatgacat tcttcttatc
    13501 ttttgtctct ttatctggaa tcaatttagg atagacaagt gtgccattgt tggtaaaaac
    13561 agaatacatt gctgcttgct ggataggagt aattagaagt tcgccctgtc catatccagt
    13621 atcagctagc aagatatctg agttaaagct atcttcatta gaaatttgtg ctggattcat
    13681 actaattggc aaatcaaggt cttcaccaaa aatgaattta tctaagcctg tacgaaattt
    13741 tttctcaccc attttcaacg tttcttgtgc cgcatatata ttatcggaat agatcaaagc
    13801 agtttttaag tctacttgtg atacatcact actgacacgc gttgttttaa aagatcccca
    13861 agaactgtct ttttgccatt taagcccgtt gatcgtcaac acttcatttg gatcgatagt
    13921 gccgttgtcg agaccgattg ctgctgtaat cattttaaac gtagatccag gagcataacc
    13981 tgtcgcaaat cggctgatga atggatgttc aggattttct tcataagctt tgtaatcttc
    14041 ttgtgagatc ccgtttgtca ttttgtttgg atcatagctt ggagagctag caagcgcaag
    14101 aagatcaccg gtttttggcg ttgtcgcaac agttgatgca gcttttcctc ctagactgtc
    14161 aaaagctatt ttttgtgcct tcgcatcgat tgtcaatttg atatctttgc cattttgaac
    14221 ttcatgttcg atcagaactt ttttctctac accgtctgca tctgtaatgc ttaatttccc
    14281 acctgttgtc ccacgaagat ccttatcaaa agccatctcc aaacctgagc gaccgatttt
    14341 tccattactg cttaattctg gattcttatc aatatcttct gctgtgatat ctcccacgta
    14401 accaatcagc tgagcagctg cttcacccaa aggataatat ctgccgtcta cttcttgaat
    14461 ggtagctcca gctggaagtt ctggcgttgc tccatcaatg attttcaatg ggacaaagta
    14521 atcgggttgt acccagcttt gtgaaatcgc ctgattgata gcatcttctg ttaagtcgaa
    14581 ggaggaagca atcgctttga tattggctgt tttttcgcct ccatctccaa gtttacttgg
    14641 aacgactcct aattgtttta gtttgcctgt tgttgctaat ggttcaccat ttcgatctat
    14701 aatattccct cttgctgctt cttgtgtggt caggcttact ttgtcatttc cttccatttc
    14761 tggaaaaacc aagttgggtt gccagttgat cgtggtttga ccatcatttc tgtctaatgt
    14821 tcctttataa gaaagatctt tcaattcacc taatgaggta ttcatctttg ctttatatga
    14881 aaaactgtaa gtagaatcgt cttttttatc tacttttaga ttcgatatct gaagtccttt
    14941 gacatcagca gcaccgtata tattctggta tttatctaag atctcttttt cagataatgc
    15001 acttttattt gccgcctttt ttgatgtcat ttctgcagct ttgttataat ctcccttgtt
    15061 caaagcttgg acaaattgct caactgtctt ttctccagct tctactgctt gggtttcttg
    15121 atagtgctgg tagtaaaaat aaccgccacc cgcagctgct attaagatca ctgcgccggc
    15181 aatataagcg cctgttcgat ttttgccgtg cttgtcactt cttttcattt tttcctcctt
    15241 ctcttgcttg tcattccttt atttcactat ttatacctgt ttattctaac atatgtcttt
    15301 gaggaaatcc ataccacaat ccagaagcac actttctgga aggttcgttt ggatactacc
    15361 aagtaatttc ccaaccgctt tgggtagctt gaatattgaa gttacgtctt tcagctgctg
    15421 agagatagct ttgatcactt gctgctgcct tctgatcctc ccgaagtctc cttctttgtc
    15481 ttcccgaaat cgagcatact ggagtaaagt attaccatcc atcacttgct ctcctttgtt
    15541 tatatatacg ccatctaaat ctagagattt ttctgcatcg atcttgactc caccaggaaa
    15601 cagttcatta acgcaatcga taaaatcttg aaatgtgata cttgcataat agggagcttc
    15661 aaatttgaaa ttttccttta atgtttgatt taataaatca actcccccat aagagtaagc
    15721 tgcatttatc ttattcattc cgtaacctgg aatatcgaca tatgaatctc tcatgataga
    15781 gatcagtttt gcttgttgtg ttttctggtt gtattgtgca accagaagtg aatccgagcg
    15841 acctccacca atcgatcttt tttcaccgca tctcctcctc acacagcaat ccacttgtca
    15901 ggtgaggagc gagtttgtct catcaaataa gtcagtcaca aaaatataaa gaaaaggtca
    15961 gaaacctttt cgaacaagaa ttctgaccta gcatcatctc atcgtccgag ttttagcact
    16021 atacaacgta aagaaaacat tcttagctat tggaaaaagc cttaatccaa cagtttctgt
    16081 tttacccatt ggcgactttc gacgtttctg ggcaacagcc tatgtttgta taggagcctc
    16141 acctaacaag gttattacta tattctattt acgagttcat gatagacttt tcctaatgat
    16201 taggcaatgg aatttgaaat gaaatagtga aatttaacaa tctttaatat tttttagaaa
    16261 aaaataacaa ataagttgaa agaatcccgt tgcaaattct ttcagttgca ccaggattct
    16321 ttgataattt tttagtttta tgtgtttttt tatatgtttt ttcacttttc ggaataaata
    16381 tttatttgtt aaagtaatta aacaatccgc taatcgtttg atctggcatt tctatttcct
    16441 taccatctaa agtaacagta gtaacgacaa aatggtcttg caatggcgga acttctaagt
    16501 actgcccttg cagaaaatca ttcactgttt catattcttt tttcatttct tttgaatctg
    16561 tcgatggttt atagcttatt tttaacataa ctagtgctcc tttttattcg ggacgtgcaa
    16621 tcgtgaaaat ttctcctatt gctgcataat catttcctgc caaacggctt acagcattca
    16681 attttcttgg atcgatcctt cctgtcttat catcatagac tgtttcattt aaatgatatt
    16741 tctgtacttc tagcaaaaat aaatcagctg ttactttatt tttattccgt atctcgacat
    16801 gttcatataa ggatgtttca aaacgaactt ttgcttctgt caatgctggt actgaaatga
    16861 ttactgaatc agttaaagtc aagtcagtca ggtacagttc gctttcctca ttaggcagat
    16921 tggctgctgt tttatttact tcttctacgt tgtcctcatc aaggatatgg ataacagctt
    16981 ctcttgtctc aagaatattc tttgctgtgt cttttactgc atcttgtttt ctctggatcg
    17041 ccaaggataa gatgggtcga ttcgaactga cgatattgaa gtaactgaag ggtgcgatat
    17101 tcactatatc ttttgctgat ttagtcgtta ctactgctac tggtctaggg atgactgaac
    17161 caatcagcaa cttgtaattt tcacgttctg tcaattctga aggactccgt tcaaacatgg
    17221 tttcgccttc tttctataaa attcgttaaa aagcagatct tgaagacaaa atgaaaagta
    17281 atgctttttt catcttctta gaatctgctt taaactatct atcaattttt cttttttgtc
    17341 aagaatctgt gccgtgcgtg ttttttagtt atttgcttta cttgcggctt cgacatatct
    17401 tttagtgatc aattgcggac gggtgataat agatccaact acgactgaaa aagcacctaa
    17461 ttcatatgct ttctctactt gttcaggaga gtcagtatgt ccttccataa ttactgggat
    17521 atcgacttgt tctatgattt gattcaataa atcaaaatca ggtgtctgcg tctttcgtga
    17581 atattctgta tagcctgcta aagtcgtaga caaaagatca aaaccatctt cttgcgcttg
    17641 aagcgcttcc tcaaaagtcg aaatatctgc catagctaac cgaccgtgtt cgtgaatcat
    17701 ttggacaagt tcagcagttg ttttttctgt cggacgttta cgagaagttg catccagtgc
    17761 aatgatttct gcttgcgtct ccaaaagttc ttccacttct ttttctgtcg cagtaataaa
    17821 cacttctgac ccatcgtaat ctcttttgat aatccctatt accggtaaat caacgattcg
    17881 cttgatttca ttgatatctt ctgtcgtatt tgctcgaata ccaactgctc cgccttcttt
    17941 tgcagccaaa gccattctcc ccataataaa agaactgtgt agcggctcgt tttccaaagc
    18001 ttgacaagaa acgacgactc cgcctttgat ttgttccagt gtatccacaa tatctcctcc
    18061 agtaatgtta tataaaaata cagcttcata taaaaatgta acccttttct attcaggaga
    18121 caataatgag ctatttcttt cagcagacct ttcttactaa aagaaaatta cttcaaattc
    18181 ttcgtatacg accagcttct cttctgtaaa ttctatgttc aacgcttctt tataagcatg
    18241 tttaaaaaac tcagcatgga ctttccgcca ataagctaat gtccgatccc cttctccttc
    18301 tttccaagca tgctctttcg tgacttcact aaaaggcaag atggtcacat ttatattttt
    18361 gatgatacaa actggttcat tttttccatt caggaccacg tctaattgac caacttttgg
    18421 taaaggctca ttctcttgtt tatacagatc gtaaccactt gatgtaccag tctttatctt
    18481 ttttacaact agttcgctca actcgtctgc cattttttct gtatccccaa atgaaaagaa
    18541 acctaatttt tctgattgat aactaggata tttttcttgg aactttttga catattcttc
    18601 tacttgctga tacataacat ccaccccttt gctttttata atgaaaaaac catccagata
    18661 ctagtataaa caattatctg gatggtgagc ataatgaatt attgaatatt caagacacgc
    18721 agactatctt caacgatttg ttttggtgtt aaatgataac gttcataaag ctgccctaca
    18781 ggaacgctat ccgtgaattc tttctctgca ccaaaattta atacgttcat tgaagaatca
    18841 ccataataac gactgatatt ttcgccaaat cctcctgaca aactaccatc ttctaatgtg
    18901 atgactaatt cgtgtgtttc ttttaattta tctaatgttt ctacgtcatt ttctgtgatc
    18961 gttcctggat tgatcaacgt tgcttcgatt cctttttttc taaaagcttt tactgtttct
    19021 tttcctaatt caagaaaacc gcctaaagct aaaattgcta cttttcctcc attatttact
    19081 gtttgatagg ctggaatact ataatcattt gcgatagctg taccatgttc tacaccatgt
    19141 gtaggaattc ggattgctac aggctgcgct gtttgttcga acgcccaatc tagcatagag
    19201 atcatatcct cttttgttgc tggagcaaga tatttgatgt tcgggatact tgataagtaa
    19261 ggaatgtcaa atgttccttg gtgtgttcgg tcactagctg agatcgttcc gccaccgact
    19321 aaaataatca ctggattctc gttgatcgct aaatcatgtg ataattgatc atatgcccgt
    19381 tgcaagaaag tacttgattg gaagacgact ggacgtactc cctgagaagc caaagcagaa
    19441 gcgaaagtga tagagtgctg ttcagcgatc cccacgtcaa aataatgatc tggatgtttt
    19501 tcttggaatg ttttcagtcc aaaggcgcct ggtatcgctg cattgactgc ggcaatagga
    19561 gctgtacttg tttgcatttt cttatccaaa taatccatga tgatcatatt aaatgtttct
    19621 ccagaagtta cttgctttgc ctccccggtg gacagatcaa atggtacatg ccaatgatat
    19681 ttcattttat tatcgattgc cggctgataa ccgcgacctt tttccgtatg gacgtgaagt
    19741 acaatcggat gatcaatatc ttttacttct tcaaataaac ggatcaccgt ttccagatcg
    19801 tttccattat ccacgtaacg ataatcaaat cccattgctt taaataggtt attgctgctt
    19861 ttaccgttgg tttgacgaag ctcagctaag tttttatata aactgccatg attctcatca
    19921 atagacatct cattatcgtt tactaatacg attagattgg attgtaaaac accaccattg
    19981 ttcaatcctt caaaagctaa gccaccactt agggagccgt caccgataaa tgctaccaca
    20041 tttcctgatt ctttcttcag atctctcgct ttagctaaac ctgttgctaa gctgatagat
    20101 gtagatgtgt gccccactgt aaaatagtca tgtttacttt catgttggtt ggaatatccg
    20161 ctcacttcac ggtaatgtcc tttttcaaaa ccattttttc gaccagttaa aagcttatga
    20221 ccataagact gatgggaaac atcccaaacg attttatcct ttggtgaatc aaatacataa
    20281 tgaaacgcaa tcgttaattc tactacacct agattcggac caacgtgccc acctacatcg
    20341 ctgtcctttt gcaagatttt ttggcgcatc tcttctgcca actgtttcat ttcctcaaca
    20401 gataattttt tgacatctgc ggggctattg attgcatcca atacatgtaa tactgtactc
    20461 ataatacatt ctctcctccg tactatcttc ttttaatgaa aatagatttg ttacacttta
    20521 tctattctac tacttagagt tgactctaag tcaatagcat tttaaaaaaa tttcagagaa
    20581 agcttgttat ataagtagat cttcgcacga atcaggactc aaataaaaac cttctacaga
    20641 caattaaaaa gctttgtaga aggtctccta attaaggtct catcaagaaa tatgtttttt
    20701 taataggtga agttcctgag caatatgata caaatggatg tttgcacctt ttaatgagat
    20761 tggatagatc tttgtctttt cagtttctaa tccattttga tagctagcag catcgcacaa
    20821 aaccactctt tttttcgcac atagacattc atcaggcaat tcttctaatg aacgaaataa
    20881 aataggattt atttcagcga tgccttcttc cgcatacaaa tgaaattggg ttcgataaaa
    20941 aaattgtttg actgaacttt ctgaaacaac aaaaatttct atttcctgtc tccccgcttg
    21001 ttcactgttg atcaaagaaa gacttttgac gaattttcga atgaaatttt cattccatct
    21061 tagttggatt tgatttttct ttttccactc ttccaatatt tctacaattt ttccgtacag
    21121 aagttgttct ttttctgata gaagatagat cctttccggt aaaaatactt gtccatctgc
    21181 ccacaacgta cggacaaatt gtaaaaagga ttgcttgaaa ataaaatttt ctgcatcgtc
    21241 gatttcagcg atactaataa tctgtaaaat caattcattc agtgataggt cattgagaac
    21301 aaaattttta taaacaactt cgaaatcttt tcttaacagc tccatgttct cattggtata
    21361 atttctactg ttgaacaaag aaaaaatata atagacatct tcttcttgta agtctagaat
    21421 tcctttttgc tcttccaatc cttgacagac taattgaaat aacggcttcg tttctgcgct
    21481 tttcttatct tcttctttca gtccaagggg aaatgccttt cttccgattg cgatctctat
    21541 tcctcgtatg ataaaggact tttcatcttc cgaatatctt cttttaaaaa aatgagtctc
    21601 tacataatca atcaactcgt tacaagcttc ttctacatac ggatttttat tttcatagcc
    21661 ttcccaattg acataacgta ctaaagctag caagatgttc cgcgagtcaa attctgggat
    21721 aatgatttct ttatttttca aataatcatt ttctttaaaa aaatccaata cgattttttt
    21781 gattgtatat actttgctca aagaaataaa ttcaagatca gccagttctg tactcgtgaa
    21841 tataccatta aaataataac ttaaaaactt taaaaaataa gattgaccgt acagaaactg
    21901 tgtgagctca gaaagagcaa taccatgttt gaatacgagt ttatacttat gcttctctct
    21961 tacttgttct tttatacaat attctagaca ctcggctaga ctttctagat cgtgaaggat
    22021 cgttggtgta gtcaccctta gagaaatagc tgtttgttcg atgtctattt cttggaattc
    22081 aaataattgt tcacacagat acacttttct aaatatattt cgctcgatgt aattttccag
    22141 cattcctgat acacgcctcc agtttttctt atgattttat ttaatcatat ctgtaaatcg
    22201 tatttttgtt tcctttttat ttagaaaagc cctttcaaaa accaataaaa aaagaaactg
    22261 ggacaaaagt caaacaagct cacaatttca gcctcattgt aggtagcttt gagccgtttg
    22321 gacttttacc ccagcctctt tcaagaatgg ttattcaaag atgtcagcgt ctagttcttt
    22381 gactacatct ttcaacaatt ggataccagc tgcgctgtta ccaaatggat ctagtgccgg
    22441 gctgaagaca cctatgccgt aacgatttgg cacagctgcc atcaacccgc cgcctacacc
    22501 gctttttgca ggtacaccaa catggacgga aaactctcct gattcatcat acaaaccagc
    22561 agttgtcata attgatttga cgattgtagc actttcttca gtaatgattt gtttgccatt
    22621 ccaaggagca attcctttat ttgccagcac agcagctaat tttgctatgc ctgtagcggt
    22681 gacattgagg gagcattgtc tgaaataagc atcgagtatc tccggtacgt ctccttcgat
    22741 catttgatta cctttcatat agtaagcaag agagcgattg atatcacctg ttcttgattc
    22801 agaatgatag atttcttcat tcaatgtgat attaggatca tcacagatct ctttcataaa
    22861 tgacaagatt cgctcaaatt tttcatctgc atctttaccg gcaatcaacg aggttgttgc
    22921 aatcgctcct gcattaacaa aaggattcat tggatgtttg cgatgattga tttccatatt
    22981 catgatagaa ttgaaggcaa aaccggttgg ttccgtgttg attgtttgaa agactttttc
    23041 tattccgttg tctttgattg ctaataacaa tacgggaact tttgacatgc tttcgatggc
    23101 aaagcgcaca tcggcgtctc ctccctcaat cagttgtttt gtatccaaat cataaatcgc
    23161 catacctaat tgtttgggat ccacttcagc taatgctgga atgtaatccg ccacttgtcc
    23221 tgtttgataa tagtggaaat tttttccaat caattgttct aattctttta cttccatttg
    23281 aataaccagc tttcattttt tatttttctg catgctggaa tttatgacgg catgcgtaga
    23341 tcgtaaatgg aataactaag acgataagat aagaaacaat cagaatcgtt tcataaatcc
    23401 catgctgtcc agctgcgata ctagcaggtg gaacaaatga gatacaaaaa gcaaaaagtg
    23461 aagtcaaaag acctaaacaa gcaacgatta cttttacaac ttttccgcct ggaacctgat
    23521 aggctctttc aagactgtca tctttaaaaa ccagcttcaa atagcccgcg aaaaacataa
    23581 agtacaacat caggtagatt acaacagtca atgacatcgc tgcaagaaat gaaagattat
    23641 tccccccgcc gcttaatgta aagacggctg cccagattgt tgcaacgatc ccatttgcga
    23701 tcatcaaatg agcaggaaca ccgtgtgtgt tttcttttgc aaaatattca ggaagtaatc
    23761 cttcttctgc tgctacgtga agtgcttttg aaggagaggt tacccaagaa gcaatttctc
    23821 cgatgacacc taaacaaaca agaatcgcaa gaattttcgc aatccatgca agatttggat
    23881 caatgtgtct taataggaat tctaacgatt gaatcacccc tgtattaaga gacaaaccat
    23941 gttgaggtac tgtagtagcg acggtcaatc cgccaaaagt atctaaaatg attgccagaa
    24001 taaccaatac aaacattgct aatggataat cctttttagg gttttccatt tcatttgcat
    24061 gactggcaga tgtttctacg cccatatatg ctaaaataaa ggaaacaaaa acaaccagcg
    24121 taggcaattt cgaaaaatca ggaatcaatg ttttcataga cagtatcgtt tgtagtggag
    24181 cgcctgaagc gacataatgg atccctaagc caaacaagac taatgctggc aacaagatac
    24241 cagctacaaa accgatccga gcaatcaatg aagtgtattt ggttcctttt aactgtgaga
    24301 gtaaaatagc ccagaaaata atcaatagga ttgccaattt cagatattta ttgttttgta
    24361 tagcaccaat acccgttgca taggataatg caccagttaa gaaatacagc atggtcaagt
    24421 agccaactgt tatctcaaac cattggaaaa agattgcggc aaaaccgaat cgttttccca
    24481 atgtgcgact gacccaagta tagacaccgc ctttttccca tcctttcacc gttgccatct
    24541 ctgctgcgca caatgccaca gggataaacc atagcaaacc gcctaataac aagaaaaata
    24601 ctaagctgaa gcctgaggtc gcgaatgtgg gatattcata taatgaaacg accattgaga
    24661 tggtcatagc caaaaagcca aagaacgtta atttttttgc aggaattttc gttttgcttt
    24721 gttgcatgaa tcttcctctt ttctatttga atttgtttca attgagtttg ttgccaaaga
    24781 agaaaaagtc caatccttct tcttgttctt cttttgtagt agtgatcgtt gtaaagtgca
    24841 tcgccgattt taaaatcact gttgtcagca cataggcata cacggcagta atgatgacac
    24901 caatcacttg aatccctaag aagtaccagc tgcttggatt cgttagtaaa tggctgttag
    24961 atgcaaagat ccctatcaga atcgtacctg tgaatccgcc catgccatga acaccccaca
    25021 catcaagtgc atcatcccat tgtttctttt tacgaaaatc aacagcagca tgacagacga
    25081 tacccgcaat gatcccaatc agcatggcac tttttgcttc tacataaccg gcacaaggcg
    25141 taatggctgc caatccagca acggatcctg ttagtacgtc gacaaaatca aagccatttc
    25201 cttttacttt tgcaatgatc agccaagtaa tcatcgcaaa tgcaagagcg atgaatgttg
    25261 aaccaaatgc attgactgct tgttcatctg ctcgaagtgc accaccggaa ttaaaaccga
    25321 accagccaaa ccaaagcagt cctgtaccga tagcagctgc cataagactg ctatgctgac
    25381 ttctttctcc taaaggaatc tttctttgac caagtgtgag gatacatgct aaagagccga
    25441 atccagctgt cgtgtggatg actgctccac cagcgaaatc tctaaatccc atctgatcca
    25501 aaaatccgcc accccatatc cagtggcaaa cagggaaata aatcagcaga ttccaaaaaa
    25561 taacaagtat aatatagcct tttaaattca atctccctgc aaaagctcct gtcatcaaag
    25621 gaacggtaat cacgataaac atcagttggt aaagaaagaa cattaaaaat ggaatcgttg
    25681 caccatgaaa catgttgggg aagcttgtaa catgtctcat caaaaagaaa tctgccgggt
    25741 ttccaataac accgccgata tcccgtccaa aggccaatcc gaatccacca aatacccaca
    25801 taatcgttgt tatcccaacg gagagaaaag attgagacat gatcgttagt atattattct
    25861 tccgtgctaa tccgccgtaa aaaaaagcta gaccaggagt catcaggcaa accattgctg
    25921 tacataaaat catgaatgct gtatctcctg tattgatagg taatgtattc atttttttcg
    25981 cctcctttct acgattacga gtataaaaga aggtgtagtt gtttttttct tctgtttttt
    26041 tgaattaata cttgcattta taaaagacag acaattaata aaagcttgat gtgttgtgct
    26101 ctttttcgtt tttcacacaa ataaagacaa aaaataaacg gtcttctttt tatagaaaac
    26161 cgtttatttt c
//
LOCUS       DAXLPC010000033        25885 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.033, whole genome shotgun sequence.
ACCESSION   DAXLPC010000033 DAXLPC010000000
VERSION     DAXLPC010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25885
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.033"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..889
                     /locus_tag="ACF3UE_001328"
     CDS             <1..889
                     /locus_tag="ACF3UE_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HFD3634750.1"
                     /translation="QLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGVS
                     SAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIGH
                     YTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTED
                     TLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYPD
                     NLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCTL
                     FGKGFGNYDQDIKLKVYYS"
     gene            complement(962..1786)
                     /gene="nadE"
                     /locus_tag="ACF3UE_001329"
     CDS             complement(962..1786)
                     /gene="nadE"
                     /locus_tag="ACF3UE_001329"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFD3634751.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(1798..3270)
                     /locus_tag="ACF3UE_001330"
     CDS             complement(1798..3270)
                     /locus_tag="ACF3UE_001330"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFD3634752.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(3907..4269)
                     /locus_tag="ACF3UE_001331"
     CDS             complement(3907..4269)
                     /locus_tag="ACF3UE_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFD3634753.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            4492..5244
                     /locus_tag="ACF3UE_001332"
     CDS             4492..5244
                     /locus_tag="ACF3UE_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3634754.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(5384..6307)
                     /locus_tag="ACF3UE_001333"
     CDS             complement(5384..6307)
                     /locus_tag="ACF3UE_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3634755.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(6322..6594)
                     /locus_tag="ACF3UE_001334"
     CDS             complement(6322..6594)
                     /locus_tag="ACF3UE_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634756.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            complement(7064..8689)
                     /gene="groL"
                     /locus_tag="ACF3UE_001335"
     CDS             complement(7064..8689)
                     /gene="groL"
                     /locus_tag="ACF3UE_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFD3634757.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(8740..9024)
                     /gene="groES"
                     /locus_tag="ACF3UE_001336"
     CDS             complement(8740..9024)
                     /gene="groES"
                     /locus_tag="ACF3UE_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFD3634758.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            9249..9911
                     /locus_tag="ACF3UE_001337"
     CDS             9249..9911
                     /locus_tag="ACF3UE_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFD3634759.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(9987..11279)
                     /locus_tag="ACF3UE_001338"
     CDS             complement(9987..11279)
                     /locus_tag="ACF3UE_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3634760.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            11449..12078
                     /locus_tag="ACF3UE_001339"
     CDS             11449..12078
                     /locus_tag="ACF3UE_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD3634761.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(12181..12990)
                     /locus_tag="ACF3UE_001340"
     CDS             complement(12181..12990)
                     /locus_tag="ACF3UE_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD3634762.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(13045..13914)
                     /locus_tag="ACF3UE_001341"
     CDS             complement(13045..13914)
                     /locus_tag="ACF3UE_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFD3634763.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(13915..15231)
                     /gene="yycH"
                     /locus_tag="ACF3UE_001342"
     CDS             complement(13915..15231)
                     /gene="yycH"
                     /locus_tag="ACF3UE_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HFD3634764.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(15228..17063)
                     /gene="walK"
                     /locus_tag="ACF3UE_001343"
     CDS             complement(15228..17063)
                     /gene="walK"
                     /locus_tag="ACF3UE_001343"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFD3634765.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(17068..17772)
                     /gene="yycF"
                     /locus_tag="ACF3UE_001344"
     CDS             complement(17068..17772)
                     /gene="yycF"
                     /locus_tag="ACF3UE_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFD3634766.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(17962..18822)
                     /locus_tag="ACF3UE_001345"
     CDS             complement(17962..18822)
                     /locus_tag="ACF3UE_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFD3634767.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(18809..19378)
                     /locus_tag="ACF3UE_001346"
     CDS             complement(18809..19378)
                     /locus_tag="ACF3UE_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFD3634768.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            19759..19831
                     /locus_tag="ACF3UE_001347"
     tRNA            19759..19831
                     /locus_tag="ACF3UE_001347"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19792..19794,aa:Lys,seq:ctt)
     gene            complement(20327..20713)
                     /locus_tag="ACF3UE_001348"
     CDS             complement(20327..20713)
                     /locus_tag="ACF3UE_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFD3634769.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(20710..21231)
                     /locus_tag="ACF3UE_001349"
     CDS             complement(20710..21231)
                     /locus_tag="ACF3UE_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFD3634770.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            complement(21233..22267)
                     /gene="sppA"
                     /locus_tag="ACF3UE_001350"
     CDS             complement(21233..22267)
                     /gene="sppA"
                     /locus_tag="ACF3UE_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFD3634771.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            complement(22300..23715)
                     /locus_tag="ACF3UE_001351"
     CDS             complement(22300..23715)
                     /locus_tag="ACF3UE_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HFD3634772.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            complement(23684..25837)
                     /locus_tag="ACF3UE_001352"
     CDS             complement(23684..25837)
                     /locus_tag="ACF3UE_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HFD3634773.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
BASE COUNT         7657 a         5299 c         4229 g         8700 t
ORIGIN      
        1 gcaactacaa ataaacgaag aatccttacc ggtatatgaa gcattagcta gtaaaacaag
       61 gatcaagatc atccagctac tttccaaaaa aaagatgaat gtcaaagatt tggcaaaaga
      121 acttggagtg agcagtgcta tcacgacgat gcacgtgaaa aagctagagg aagcaaacat
      181 catcaaaaca gaaaaagtag gacaacaaaa aatttcgagc cttcgtgtcg ataaaatcga
      241 tattagtttt ccagaaaaaa tattcaatgc ttttgatacg aaagaaacat cgatacctat
      301 tggtcactat acaaattatg caattgaacc aacatgcggt ttagctacga tccatgattt
      361 tatcgggaaa gtggatgaac cacgctattt tatggatcct cgaaggatgg atgcccgcat
      421 tctctggttt accagcggat ttgtcgagta tcaggcacct aattttttaa atacagagga
      481 tacattggag atgttggaag tttctgtgga aatttcttct gaatttcctt tttcaaatga
      541 caattggcct tcagatatca ctttcagcct aaatggtgtg gagctaggaa catggacgag
      601 ccctggagat tttgctgata tccgcggtaa atatacgcct gattggtatc cagataatct
      661 taatcaatac ggcttgctga agacgatccg aattaccaaa cacttgacga atatgaatgg
      721 agaacccttg tcaaacatca cgatcaacga catccctaaa gagcaagaca cttggcattt
      781 gcgaatcgaa gtgaaagacg atgccaaaca tgtggggggc tgtactttat ttggtaaagg
      841 attcggtaat tacgatcagg atatcaaatt aaaagtttac tacagctgat atttttcttt
      901 tctattttat aaaacaaaaa cagccaatcc ctatgaaggg acggctgttt ttgctttatt
      961 gttatttcca gaaatcatcc aaaacggaaa ttggcaaatg tcgtttatgt tgtgtcttgt
     1021 tccaccatgc ttcgattttt tcttgtgctt gagcgggaac ttcttttcct tctagataat
     1081 catcaatttc attatatgtg acacctagtg cgacttcatc tgcaatcatt ggtttcccat
     1141 cttcaagatc tgcagtcgga atttttgtgt ataatttttc cggtgcattc aatgcttgaa
     1201 gcaattgttt cccttgtcgt ttgtccaaac ggaataatgg caaaatgtcg gctccaccat
     1261 caccaaattt cgtgaagaat ccagtaatgt tttctgcagc atgatctgtc cctaatacgg
     1321 ctcctgctct ttctccagct acggcatatt gcgtaatcat acgttgacgt gctttgatat
     1381 ttcctttgtt aaaatcgctg attcccacac ctgcttcgct taatacttgt acttgtgcat
     1441 caacagctgg tttgatattt actcgcagac taacatcggg ctggataaag tcaagagcag
     1501 cttttgcatc ttcttcatct gcttgttcac cataaggaag acgaacagcg ataaattgat
     1561 agttttcatc ttttgtttct tcacgcattt cttccatcgt tagttgcgcc aaacggcctg
     1621 ctaaagtaga atcttggccg ccgctgatac ctagtacaaa agttttaaga aacggatatt
     1681 ttttcaaata tgctttcata aagtcaatac ttttacgtat ttcttctttt ggatcaattg
     1741 ttggtttgac acctaattca ttgataattt ctgtctgcag gctcatttat tctcctccta
     1801 tgcttctgta tgaagttctg ctacgctttt tttcattcgt tccatgatag ccattttatg
     1861 gttccagcat tcagtagaca gatcgactgg gtatttttgc ggattcaagt ctcgtttata
     1921 ctcttcccat agtgaatcta gattttcttt tgtatattct ttgatttcgt ttagtgcagg
     1981 taattcgtaa actctttttc cttcgataaa gatatcttgt aaaactgggc gagctgtaaa
     2041 gtctcgaaca gttttattga taaacgtatg cactggatgg aacatgaaga tagcttcttc
     2101 ttctcgaggg tcttcatccc ataatgtcac gtagtctcct tcagatttcc catcaaaatt
     2161 tcgagtgatg cgccacactt gttttttccc tggagtagtt actttttctg cattgcttga
     2221 taacttgatc gtatccatca tttttccttc atcatcttcg atcgatacta gcttgaatac
     2281 tgcaccaagg gctggctgat cataggctgt gatcaatttt gtcccaacac cccatacatc
     2341 aattttagct ttttgcatct ttaaattcaa aatcgttgct tcatccaagt cattcgaagc
     2401 atagattttt gcttccgtaa atccggctgc atctaattgt tcccgaacac gcttagatat
     2461 ataggccata tctccactgt cgatgcgtac gccttggaag ttgattttgt cacctaattc
     2521 tttcgccacg cgaatcgcac ttggcacacc tgatttcaac gtatcataag tgtcgactaa
     2581 gaacacgcag tctttatggg ttttagcgta ggccataaat gcttcataat catttccata
     2641 agattggact aacgaatgag catgggtccc gctagctggt atcccaaata tcttcccagc
     2701 acgtacattg cttgttgcat ctgctccgcc gatatatgcc gctctagttc cccagactgc
     2761 tgcatccagt tcttgtgccc gtctagttcc aaattccaat agtggatctt ctccgatgac
     2821 agatttgata cgagctgctt ttgtcgcgat caacgtttgg aaattgacca tattcaacag
     2881 tgctgtttct actaattggc agtgcgctaa aggcccttcc acttggatca atggttcatt
     2941 tgcaaaaact agttctcctt cacgagcaga acgaactgtt gctttaaatt caaaattttg
     3001 taaatactcc aaaaaacctt caggatagac ttctaatcca cgcaagtaag caatatcgga
     3061 atcattgaac gtcagattct ctaaataatt gactaaccgt tccaatcctg caaaaaccgc
     3121 gtatccgtgg ttaaaaggca tttctcgaaa gtaacattca aaaacagcat gtaaatcagc
     3181 tcgacctaat tcccagtatg tctgcatcat attgatttga tatagatccg tatgcagcgt
     3241 caaactgtcg tctgggtaag tattattcat cttgtattac tcctcttggc aagttttcat
     3301 ttcctaccca ttataacaaa aaaaattaat aggaaaagaa atcttccatt ttttctgaaa
     3361 aagcacatgt tttacggata tttcttgcta aaaatgaact ccatctgcta aaactatcct
     3421 ttcttattgg tatttaacct aaacgagaaa gaatacttat tttattcaat gtatccgaga
     3481 cacgaagaaa ttagcgtttt ctatttttct tacttgataa aataagtaga ttttcctact
     3541 acaatcgtag ccgttaagat accgatgatt gaacaaatat aaccaaatgt ctctacaaca
     3601 taatcaatgg caaaagtttt tgaagcaata atacgtcttt ccttttttgc ttcttatccc
     3661 caaagaaacg gatataactt attatgtatt gaattttttt ggaaaggcga attatgacaa
     3721 gatatacctt gcgttgaaaa aactcgcgga aaaaatatca cacgttttta aaaagataca
     3781 aagtaagaaa gcagctgtca atagaatgga aacaaaaatg gcgagacatc aatcagtctc
     3841 gccttgtttt ttattgtata cattagatat ggagcaggtt accataaaga tgattattag
     3901 tcgttattaa atagaatcct tcgtattttt ttgttctatc actacaatat ctttatttgg
     3961 acgtttgaat tgtattccgg cacgttctag ctcctgtttc actcctacat ggactttgac
     4021 atcttctcgt gtcattttta aaacgtgatg aatcgcatag tcgatttctt gccttgtgat
     4081 ttttttcttc gtattgatca tcacgacttg ctttttatca tatgtgtcta ccaatagcag
     4141 ttgtgttcga tctaacgaaa ataatttgta ataattaata gccgtattcc caaaaaagaa
     4201 ttccactact ttaggataaa atgtcttaat atttaaatta ctattcacag gtgtttcgat
     4261 tagcttcatc tcattcctct tttctatata gtcgatttag atccaatctt aagttatgtt
     4321 accatctttc ctagcattaa ggaatcggtt acaattgaac ctttaaagac aaaaggattt
     4381 accttttatc acttaatagt ataacataat ttcatgagaa aaaaatacaa ttttttcttg
     4441 accatctcgt tacgtaaagg attatgctta catttgtcag gaggaaaaat aatggagtac
     4501 acaataaaga aaatgtcaga gatatcagga gtcagtccga gaaccttgcg cttttatgat
     4561 gagattggac tgctaaaacc agctaggatc aattcttcag gttatcggat ttatggcaaa
     4621 aaagaagtcg atcgtctgca acacatctta ttttatcgaa caatggcatt caagttggat
     4681 gatatccaag aggtcttaga caatccatct tttgaccacc agaaagcttt aatcaagcat
     4741 cagcaaatgt tgctggaaaa acgggcacaa atcgataccc tcttgacaac tgtccaacag
     4801 acacttgata tgtacgaagg aggaagaaaa atgagtgaca aagaaaaatt tgaagggttt
     4861 aaacaacaaa agttgaaaga aaatgaagaa tcctatggac aagagattcg acaaaaatac
     4921 ggaaaaaaaa aggttacagc atccaatgaa aaatggatga atatggataa agaaacgtat
     4981 gaagaaatgc aaactgttga aaagcagatg ttatttgatc tcactcttta cttaaaagaa
     5041 ccagaagatg aaagcttagc agaccgtatc ttccaagctc ataagaagtg gttatcttac
     5101 agctggcctg aatatcagcc aaaagcgcat aaaggactag gaatgatgta cgaagccgat
     5161 gaacggttca ctgcatatta tgacgagcga agtggtcatg gtgcagcaaa agctttaaat
     5221 gaaattatcc aaaaaaaggc gtaatctttt acatgatcca acaaaaaagt acacgtaaaa
     5281 tgacctaata acaaaacagc agacacccaa gttagatttt tatgctaact tttggtgtct
     5341 gctccattct ttcacaagtt ttttcatcct actttaaata tattcatcgt tgaataaacg
     5401 tataaggtat tttcacttta tccttttttt ctgtaagaaa caattgaaat gccatttctc
     5461 cgcaagcttc cagatggtgg tcgatggttg ggaaaccaag aagctcgctg atcagcaaat
     5521 tatcgcgtcc aatcaccact ggtgtcttat cttgcagata gctttgcaag atgcctgctg
     5581 caaccatatc cgaatttgta aagacaccat caactccaag ctctttaaaa aagaagcctg
     5641 cttgttttcc tttctctgca tctatacaat cccaaaaaac aagtgattca tcaaaagatg
     5701 gaaaaagttg atgacatagc tgcaaagtga tttttgagtt ataacttagc ctgccacttc
     5761 gccccaacgt gatgcccaat tgctttatac cttgctgctt caaataagta agaccttctg
     5821 taattgattg ttctcgatca ataaagacac agcttgcctg ttttcccttg atttcttcac
     5881 aaaaaactag aggtccatat ttttgatatg ccaataaatc atctagtgta ttggcacgag
     5941 acgtaatgat caatccatcg aaagctttag ctgcaaattc ttcaagatac cttcgctctt
     6001 tttctttctg atagcccgtc ggtaaaagtg tcactttgta atcataatca aacgctgctt
     6061 caatgatccc actgatcaac tgatcaaaat acggatgatt ggtataaggc agaatcactc
     6121 caatgctttt cgtttttcca taacttaact gtctggcatt tgcattaggg atataatcga
     6181 cttctttcat gaccgcaagt atttctttcc ttttttcctc atctacatat ggatgtccat
     6241 tgattacacg tgaaatagta gaaactgaat aacctgtgag ctttgcgata tctcgaatgt
     6301 ttgccactgc tgcttcgcca cctatacaaa aagattttct tgtaaatagt ctaccacagc
     6361 tggaccgcat tcaaaaaact gatacatttt tccttcatgc gaaaaactga tccgctgccc
     6421 gccccaatat atatcttttg tcaaattttc gatttcattc attggtattt cttttactat
     6481 attcctattc aacccttgaa aactgtacaa cgttaatacg gatcccttga actcgacaaa
     6541 cgcataaaaa taattgttcg ttgtgccatc tgttatctct acataagtat tcattgcaag
     6601 ccctcctttt gatactttga gtatagtgta tgaaacgcgt ctcatagcaa ggagtttgtt
     6661 ttgccaaaga aaagttttat tcctctttca ttattaccaa agtctcttat tttaaattga
     6721 atacattata atgatactgt aaatatatct ttattattag tgaatggata tttactttta
     6781 atagataaaa aattataact attaaaaata actattttca ttataattac acacaaaaaa
     6841 gagcgtgaga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt ataaacagcg
     6901 gaagcagaag caactccttc ggaaataagc tgaaattcac aaaaatttga aaagcaattt
     6961 ccgtgaattt cttcttattt cttggagtta aacgcttctg ttccagcctc tttttatctg
     7021 tctttcacta atgatcagtt gtagataagc aagttgcttt ttcttacatc ataccgccca
     7081 tcattgatgg atccattgca ggagctgctg gcgctgctgg ttctggttta tctgcaacga
     7141 ctgcttctgt cgttaataac aaggcagaaa cggaagcggc attttgcaag gcagaacgtg
     7201 ttactttagt tgggtctacg atacctgctt caaccatgtt tacccattct ccagtagcag
     7261 cattgaaacc agtgcctagt tccacgttct tcaatttatc aacaatcact gatccttcat
     7321 aaccagcgtt ttcagcgatt tgacgaattg gttcttctaa agcacgaaca acgatcttga
     7381 tacctgttgc cacgtctcct tctgcttcta cagcagaaac tttgctgata acgttcacta
     7441 gagctgtacc accacctgag accattcctt cttctactgc ggcacgtgta gcattcaatg
     7501 catcttcaat gcgtaatttt aattctttca attctgtttc agtagctgca ccaactttaa
     7561 caacagctac accacctgct aatttagcta agcgttcttg taatttttcg cggtcaaaat
     7621 cagaagttgt ttcagcaatt tggtttttga tcaattgcac acgagcttcg attgcttctt
     7681 tttctccaga accttctacg atcgttgtat tgtctttatc tacaacaact ttagaagcat
     7741 ttcctaagtt ttcgattgtt gcatctttca attctaaacc tagatcgtca gtaattactg
     7801 taccacctgt caaaatagcg atatcttcaa gcattgcttt acgacgatcg ccgaaaccag
     7861 gagcttttac agctactacg ttgaatgttc cacggatttt gttcaataca agagttggca
     7921 atgcttcacc atctacatcg tcagcaataa tcaacaatgg acgtgattgt tgcaagattt
     7981 gttctaacaa tggcagaata tcttggatgt tagagatttt tttgtctgtg atcaagatat
     8041 atgggttttc tagaacagct tccattttgt cgttatctgt taccatatat tgtgataagt
     8101 aaccacgatc aaactgcata ccttctacaa catctagttc tgtttcgatc ccttttgatt
     8161 cttcgattgt gatgacaccg tcgtttccaa ctttttccat tgcatcagca atcaaatgtc
     8221 caactttatc agaacccgaa gaaacagctg ctacttgtgc aatggcttct tttgaatcaa
     8281 caacagttga gatattatgc aattcttcga ctgctgcttt tgttgccaat tcgatcccgc
     8341 gacgaatgcc tagaggatta gcacctgcag ttacgttttt taaaccttcg cgaacgattg
     8401 cttgtgtcag aacagttgct gtcgttgtac cgtctcctgc aatatcattt gtttttgatg
     8461 ctacttctga tacaagtttt gcacccatgt tttcaaaatg atcttctaat tcgatttctt
     8521 ttgcgatcgt cacaccatca tttgtgatca atggagagcc gtaagatttt tctagtacga
     8581 catttcggcc tttaggtcct aatgttactt tcactgtatc tgctaattta tctaccccgc
     8641 gtaacatagc tgcgcgtgcg tcttctgcaa atttcaattc ttttgccatg attgattcac
     8701 ctcattgatt atttttgatt atttttttat cttccaaatt tactcaacaa tcgccatgat
     8761 atcttttcct gcgacgatca gatattcttt tccttcgtat tttacttctg taccggcgta
     8821 tttttcgaac ataacttggt cgcctgcttt tacagcggca ggaacttttt caccgttttc
     8881 taacaaacgg ccttcaccga ctgcaacaac tgtcccagtt tggggtttct ctttagcagc
     8941 agaagctaaa acgattcctc cgacagtttt ttcttcttct tttgcgactt cgataatgac
     9001 gcgatcacct aatggtttta acacgataaa tccctccgat aactcttttt ttaatctgtt
     9061 agcactctta accttcgagt gctaacctac atttttaata atactcattc tccctctttt
     9121 ttgcaagctt ttaaatcaaa gaaaagaaat tttattctga cagctgctta ttgaaattat
     9181 gatataattg aaatcaatcg atataagctt gccttgcatg cttgttatcc cttaaaagga
     9241 ggaattacat gtctttaaaa aaatatagct tcctcagcat tttttgctat ggtctaattt
     9301 ttatctcacc cttgatccta gcttcgatag gacttgtaaa atctacgtct gaattgatca
     9361 cagcaactgc agtcatgtat atactaggcg ccgttgtcct agctattttt tattttaagc
     9421 aacgtgaacc cttagcgatc gaatcagcgg taaaaaaagc ttctgctcca aagattgtta
     9481 tttatggatt ggttggaatc tttgtcgcat tgattctgca aagcatcgct gtcatgttag
     9541 aatctgtatt gtttggcaaa gcaacccctt ccgagaatac acaaaatatc atccagatga
     9601 tcatggaagc acccgctttt attttggcga caactgttgc tggacccatc atggaagagt
     9661 tcgtattccg ccgcagtata ctggggatca tcagtcgata ttcaaatttt tgggtcggag
     9721 cagtgatcag ctctttgctg tttgcgtttg ctcataatga tggtcatctg ctaatctact
     9781 ttttcctagg tttcttcttc agcctagagt acaaagcaac tggtcggatc tggacatcga
     9841 tgatcacaca cgtaggaatg aacacattag ttgttcttgt tcaattagct gtccaaaaag
     9901 ggctagtata aacatgacta taaatactcc tgtcatccta gattggtgat tttcccaatc
     9961 taaagcgaca ggagtatttt tgttttttag tcgttcatct tttctgctgc tccatcattt
    10021 tttgtctgtc tttccttttt gcagtttgca gaatctattt ttttcaaaaa tgggaaataa
    10081 atgaaaaaac taattgacaa cacgatacct tgtaaaatcg ctgcaggcac tccgcctact
    10141 aagaaacccg agaggatcgg cggtgttgtc caagggactt ggactgctgt aaataaagga
    10201 acgaatccaa aatataaagc ggaataggta atcaatcctg aaacgaccgg tgcgaaaata
    10261 aaaggaacag ccatcatcgg gttcatcacg atcggtgtgg aaaaaataat tgattcattg
    10321 atgttgaaaa aggctggtaa aagagcaaga tttcctaatt ctctgtattt cttcgatttc
    10381 gcaaaaaccg tcataaaaaa tacagcccct aacgtcaatc cagcacccgt aaccgtcatg
    10441 aactgatcga gaaattgctg agtaacgata tgtccgccat ttgccaccgt caactcttgt
    10501 cctgaggcta agatttctgc atttgctaat gaattcgctt gcaagacggg actaaccaac
    10561 ccattgacca tcgcagatcc atgaagacca aataaccata aaaacggaac aaaaaaacct
    10621 aataaaagca caccaaacaa cgtgtctatg aacgattgaa tgggaagctg gacatatgtc
    10681 catactcctt gaacaacagt cattctgaac aaatgttgaa aaaccgctga accgataagc
    10741 gtaaaagtga ctataacaat gattggaatc aatgaagtaa aagactgcca aacattttca
    10801 ggtatcttct ctctttgctt ccaccctttc gcaagtctta ctaaacgtgc atagccccat
    10861 ccgatgatga gcccagttgt aactgctcct agtatccctt cagcacctgt ccagacagta
    10921 tctatctgag tatttagtgg ctgaataagc agtagataag cagacaaggc tgttatgccg
    10981 actggtaagc gatcgatgtc ttcttctttt gcataagcgt atgcaatggc aaaaacgatc
    11041 caaaaggcta tcacatcaaa tgtagcctgg tatacttgtg taaaatacat agaaaatcct
    11101 gttttgtcta tccactgagc gatgtaatcc acaggaaaat gagcaaataa gaaaaacagc
    11161 gagccaacaa taattattgg gatcgtgtaa gtcattccat tacgcaaagc agttaagggt
    11221 ctaagattca caacagatgt tatcattggt aaaaaggcac gatctaacca ctctttcatt
    11281 tcttatctcc ttcaacttct atttttatca atcagttttc ttaatttaac tatacccaat
    11341 gatcacgaac catgaaagga atgcgcactg agcttttcaa aaatcggatt ctttgacgaa
    11401 tattcagcaa ctgcttacaa tggacaggaa taaaaaagga ggttttttat gaaaattgca
    11461 ctcattggag ctactggcca tgcaggttca tttattttag acgaagcatt gtccagagat
    11521 ttagacgtga cggcaatcgt gcgtcatcca gaaaaattgc catcagatgt tccgtttata
    11581 caaaaggatt tatttgagtt gacaactact gatcttgcat cttttgatgt tgtcgttgat
    11641 gctttcaacg ctcccaaagg aaaagaagaa atgcatcaaa cttctttgtc ccatttgatt
    11701 gagatgcttg aaggaaccga tacacgctta attgtcgttg ggggtgcctc ttcgttattc
    11761 ttagatacag aaaagacgac tcgtatgatt gaccaagtac ctaaaaatgc acccttctat
    11821 ccaacagctt tcaatatgta cgaaggattg ttaaaattga aacaatctaa aaatctacat
    11881 tggacttata tcagtccagc ttctttattt gatccacatg gcaaacgtac aggtacttat
    11941 ttgttaagtg atgattattt acaaagaaac gctgctagcg acagtacgat cagcatggca
    12001 gattacgcga ttgcattagt agatgagata ctggatgaga aacatgaaaa gcagcacatc
    12061 agtgtagtca gtcgataata cggttatttt tttaatatgc taaaaaaata aaaatagaag
    12121 ataaaaccaa ccctgattga ttttatcttc tgctttttat atttttattg attgaactgt
    12181 ttaaatcgaa aatagctcag ttgcttcatc tggatctgta tcatagattt caaaatcatg
    12241 tccaacgcca aaatcttttt ctttcaaaac attttccatt gttaaatgag caagttcttt
    12301 catattgttt tccttgctaa gatggccaag atagattcgt ttggtccgat taccgatcac
    12361 atcagtcatg acaagtgcac cgtcttcgtt ggaaagatgt cctctatctc ctaaaatacg
    12421 ctgttttaaa ttccacggat aaggtcccat gcgtaacatc tcaagatcat gattactttc
    12481 catcaaataa ccatcggcat tttcaatgac acctcgcata taatcactgc aatatccggt
    12541 gtccgtcaac atgacgaatg accgattttc tttatggaaa cgataaaatt gcggagccgc
    12601 tgcgtcatgg gagacgccga aactctcaat atcgatatcg ccgaatgttc tgactttccc
    12661 catctcaaat agatgttttt gttccactgg tacatttcca atcagtggtt ccatcgcttc
    12721 ccaagtctgc tgattggcaa aaacatccaa atgatactta cgagccaaga cacccacgcc
    12781 atgtatatga tctcgatgtt catgcgtcac aagtattcca tctaattggt ccggtgtccg
    12841 atcaatttga gccatcaagg aagtgatttt tttaccgcta agtcctgcat cgaccaaaag
    12901 ccgttttttt tcactttcga tataaagtga attacccgaa cttccacttg ctaggatact
    12961 gattttaaaa gctggttttt cttcagccat ttgactccta cttcccttct tactttgtaa
    13021 acttttttca ttatactcgc ttttttattg atcttccact tttggtacag tattgtttgt
    13081 cacgatcgta ttgctgaaag cgttgacgct ctcaatttgg accactttat cgcttgtttc
    13141 gatcgctaca tgccaaacag gaacatacac atttttttcc cggactttca gaatacagga
    13201 ataagctagc tgacgccata aaatttttga tcctcttggt attttgttat tgatgtacaa
    13261 tgtattgatt gcttcctctt ccgtatacag ttccgtcttt tcgcgcagct gctcgatatc
    13321 agataaatgc gtctgcatgt atttcgtgat gctataatca ttatcgtttt tttctaaaga
    13381 aagaacgatt tttgctgtat catcattgaa tgggatgcct tcatactctt ggcttgcttg
    13441 gatttctagt ggttcttctt ctaaatgaga aaagtttttc gtgtacacat aatcattacc
    13501 gaataaaata ttgtctttgt tagataaaaa atcttccaag gaactactaa ttttatctgg
    13561 atcgatcacg ttcttttcag catctgaact ggataaagat ttcgtcaaaa catcaccgtc
    13621 taaaaacaca ccacttgcca gcaagccgct tttaccagcc ttgcgataat tcgctaatga
    13681 agtgctaaga ttggtctgct ccgcgctaag ataatagcct tgcttgttct cagacgaaat
    13741 cttccccgtg taagtgatat cgtcgctagc cagacgttgt tggattgatt cagtctgatt
    13801 agagcgaatg acattgtttt cttggtatac cgcgtcatga taactgctga ataaaaacac
    13861 attcaaccct aaaaaagcga cgaaaaatat ccattcgatt tttttgaaat ccaattaatt
    13921 cgcctccaat ccaggtaatt tttccagaag gtcgttagct gaataccagt tatctttata
    13981 tttcacatac cattcaggta agagatcaac gacacgattc gtttctttga cattttgcca
    14041 tgtatagcca acgatcactg aaccaatctt gttgctatct gctcccttag cttttaactg
    14101 ctggatgatt tcattcgtac ttgcaagttc tacttcttcg tctgaaggta tcggcacttg
    14161 aatcgtattc aaactggttt ggatattcac ttgcacagaa ccattcgttt caccgccaac
    14221 ttccacacca atctgtcctc tgctgtctgt cccaaaaacc gggaagcctt ccacgaatat
    14281 ccgataatcg atcgtattgt cactgcggtc aaaatatctg aggttcccta aagaactgcc
    14341 taatttgcta atatagggga aactttcaga aaatacacta gcattttctt ttttctctgg
    14401 cagctctcca cgaaaatcaa ctacttgcgt ttccgaatgg atagacattg tttcattccc
    14461 accgtaaaaa atcaattcat tgctttcatc attatttttc acgctatctg gtttctggaa
    14521 aaaagcattt ctaaaaagtg tatagggttg ctgtgacagg atataactat acttcttcag
    14581 tttgatcgaa tgtttcgtag catattgcgt gtcgatcgtc gatggttctg ttgtcatttc
    14641 tgtccatttt gtgtcttttg ctgttaattc tttattgata tctgtccaat tcaacgaaat
    14701 atttgcttca tatacgagat ggttcgaata attcaaaaat cggatttttt tatttccttg
    14761 atcgaattgt attctagtaa aatacatatt ttcgctttct tttgccaagt tcgacacatc
    14821 taaatctaaa tcaaatgctt ccttgtattc tcttagcaaa aaaggcgcat tataggccaa
    14881 ctcaaaacca gagttcagat ttttcacctg ttcaaactgt gatttgtctc ctgaaactac
    14941 ttcagaaagc tttccaaatc ttgctttatc gatgatcaat tgcaatcggt acacgagatt
    15001 ttcactgttg gtttcttgga tcattcccga atggtgccat gtaacatgaa gcggaagaaa
    15061 gacttcggaa gtttttcgat tgctttgaga ctcgatcatt tgagtgtttg tctcatctac
    15121 gttgattgaa ctttttcctg ctgggctcag ccagattgca taagagaagt atatgcttaa
    15181 cgcaaccatc aaaatgagtc ctatacgaac gactttttca gagattctca ttcccaccat
    15241 tcctcctcat aaggttcata tggcagcgag atataaaaag tcgacccttt tccttccttg
    15301 ctctctgccc aaatagcgcc tcgatgcgcc ttaatcactt ctctagaaat agctaatcca
    15361 agtcctgtcc caccttgtgc tcttgcacgt gctttatcta ctcgatagaa ccgctcgaac
    15421 actcggttca gatctttttt aggaatcccc aatccttgat cggtgatact taaaatcacg
    15481 ttattatgcg tttctaataa gcgacaagta atcgttcccc catctggtga atacttgatc
    15541 gcgttattca tgatattatc gactacttgg atgattttat ctgtatctac ttcgacccaa
    15601 agatctcttt gcgtaaattc acgacggatc ttataatttt tttcctgatt tcccaccatc
    15661 atatcaaacc ggtcaagaac aaaattcact aactcgttga aattgacata ttctaattga
    15721 agctgggtat tacctgtatc catgcgagat agatttaaga ggtcattgat cattcgaatc
    15781 attcggtctg tttcatctag cgttaccttc aaaaaatttg gtgctacttc ctcgtctttc
    15841 cacgcacctt cgctcaatgc ttcgatataa ctacgcatac ttgtcaacgg tgtacgaagt
    15901 tcatgggaaa cattagagac gaattcacga cgttcccgtt ctgttttttc ttgttctgtc
    15961 acatcatgca agacagctac taatccgctg ataaaacctg attcgcgacg gatcatagaa
    16021 aagtctactc gcaagatcat ctgatcactt tccaatgtac tggttgaacg gtcaagtacc
    16081 atttcgtttg gatcttctaa taatttccgc aacgtatatt cttcttcgat atctaaaagt
    16141 gtcaaaatcg attgtccgat tgcttcctcg tttttgatat ctagcaagga aacagccata
    16201 tcattgatcg taatgacttt acccctgcga tctgtcgcaa tgacgccgtc tgtcatatgg
    16261 gatagcacgc tatccaaacg attgcgttca gcttccattg tatcttgagc ttcttcaata
    16321 cgttcagcta actgattgaa ggtatcagcc agctgtccaa gttcatcttg tccatgcact
    16381 ttgactttcc gactgtagtc tcctctagcg attcgaatgg cttgttctct catttcaccg
    16441 atcggctgtg taatcgaacg agcaactaaa acagatacga tcattgaaat aaatgccgca
    16501 attagtgagg cagtaaagaa aatgactgct gtgttattga tttccgaata tttttgttcg
    16561 atattacttt tgacgtaaag agccccgata acggcatcgc cggtcgggga caggatcggt
    16621 tgaacattga tattcacccg tttatcgtcg ttatctaaag caacataacg tttagtcgtg
    16681 aaatcattga tatcaacata atcatttttc tttcccacag cgctttgttc attgacatcg
    16741 gttgttcctc ggatgatccc tttttcgtca acgacccgta tttcgatgat atcgctagtc
    16801 gcactgtttt caataaatct tttgatattc gcatttacct cttcatcatc tgcattatct
    16861 tttcgattca attccgggct gattgttgtt gctaatgatt ccaccgtttg attcatatct
    16921 ttaataaatg tattgatcgt ggaacgttct aaaccacgta taaagtaggc accaataatt
    16981 tcgatcgaga tcaataaaat cagaataaag gtaatagcga tcttaaaatt gactgatcga
    17041 aaaaagcgga cttttctttt catccaatta ctcctgttct gggttacgca aatagtaacc
    17101 gacaccacga cgtgtcacta aataatttgg atggcttgga ttatcttcga tcttttcacg
    17161 caaacgacgt acagttacat ccactgttcg tacatctcca aaataatcat aaccccaaac
    17221 cgtttgtaat aaatgttctc ttgtcatcac ttgtccaagg tgcttcgcca agtaaaagag
    17281 tagttcgaat tcacgatgtg ttaactcgat tgtttctcct cgtttcgtca ccatgtaagc
    17341 ttctggatgg atcgtcaaat caccaatcgt caattccgca ggtgctgcct cttctggttc
    17401 cttcgcagcc gtggcaccgc gacgaagatt tgctttgaca cgtgcaacta attctcggtt
    17461 ggaaaatggc ttggtcacgt aatcatcggc gcctaactct aagcctagga ctttatcaat
    17521 ttcagaatct ttggctgtta ccataatgat cggcatatca taagttttgc gtacctcacg
    17581 agcaacttct aagccgtcca ttttaggtag catcaaatca agtaaaatca aatcaggttc
    17641 tacctcagca actttttcca aggcttcttc cccatcatat gcagtataaa cgtcatagcc
    17701 ttctttggct aaattgaatt tgacgatatc cgaaatcggc ttctcatcat cgacaactaa
    17761 aacttttttc ataaagagcc acctcttata tattattgtc ataccttctc attataccgt
    17821 atttctgctt ttgtttcatc tttgcctata aaacaaaaga gaaaattaaa atgaaagtgc
    17881 aaaatacttt attatttttt gttctaactt caataaaaaa ggaaaacact gattttcacc
    17941 tcagtgtttc ctttttttga tttatccttc taaaacttgt acaccgacac ccaataatcc
    18001 cggaccagtg tggactacta atgccggaga aatctggcca aagtagattt ggtttgcttg
    18061 tgggaactct cttttaagtc tcgcttccat ttcaattgct tcttctttcg catccccatg
    18121 ggcaacagct aagttgaaga cctttgcatt accgattttt tctttgacgt aagcaaccgt
    18181 tttatccaaa ctttttttac gtcccctagc ttttcctact gtgtaataaa tcccttcttc
    18241 attacatgag atgattgggt taagctttaa agcggttcct acaatagaag caactaaacc
    18301 gatccgtcca cctttttgaa gatattccaa tgtcgcaaca ttaaagaaaa cttttgttct
    18361 ttcgactaac tcattcagat tactgatcag ttgatcccat tctactcctt cttccagcca
    18421 ttttgctgct tggatcgcag aaaaacctgc accaatacca atatttttcg tatctagtac
    18481 atatgcttcc aattcttctt gctgttgtgc aattaaacga accacattat atgtcccgct
    18541 caatccactg gaaattgtta ccgcaagtac cttttcataa ccgtcttttt tgatttgctc
    18601 aaagatttct gtgatcgact caccatccgg caaagatgta ccagggattt cctctggcaa
    18661 acgttgatag atctcttcag gggtaatgtc aattttatct gtatatacct gatctttata
    18721 aataattttc aatgggatca tatacatctc gtattttttt atcaattctt ctggaacatc
    18781 cgtacctgaa tctactaaaa ttgcgatttt attgtttttc atttgttttc tcctctttta
    18841 aatattcggt ttctagaaca atcgtttttt ccgcaagaag tttcattgca aacgataaag
    18901 ttgccgctct tacagcaata tattctacag gggttgcctg gtcgaatttt tgcggatgag
    18961 atttaccttg tgctaattgg ctgaccatcc acacagctgc ttcttgttca tcgcaaaata
    19021 gattataggc ttcacgaatt cctactgttt ttccttggaa caatatccct tctttgattt
    19081 caggaatagt caatacttgt ttcaacgtag tgattgcaag taaaaatgct acgtgttctt
    19141 tgttatatct ttttttaact ggtgctggta tcaaacctag tttaacgtaa ttgtttacca
    19201 tagaagaggt aagcaatgga tgcttttctc cttgtatcac aggtgaaaga taacgatcaa
    19261 ctaacgttct gacttggtcc atataaagtt ctaagtcagg gagttcttcc cagtgaggca
    19321 gacggaatgt ttctagttcc ttcccccact ccattaattg ctgacgcatt ttttccatca
    19381 taaccgctcc ttttttcatt tcataaacat gatatcagac ttatgataaa cattcaatct
    19441 agttgcttta actaggtgat ttgattagcg ggattctatg aaaacaaaaa acaagaaggc
    19501 taagccttct tgtcttttat cgttaagaac aggagacccg ccggggagac ggcgggaaag
    19561 gagtaaaaaa tgaaaaaagt gttagggttt gttctcttgc aagaactttg tttgttggta
    19621 tgcttatata atagcgagca aatgtgaata atctatgaat gatttcctat aaggaagtaa
    19681 agatttttct gattttcttt aaatgtagtc ttgcatttta aaattcttag tgctactatt
    19741 attaagtact ttttgtacgg gccgttagct cagttggtag agcagctgac tcttaatcag
    19801 cgggtcgcgg gttcgagccc ctcacggccc attgggtgcc aaacccacgg aacaggtaaa
    19861 tgttggtgcg aaagcatttc gaaaacattt acgctgttct ttttttattt ttcaaaataa
    19921 ctagggcttt ttatttttaa ctcaaagtcc actgtagccc tttggacttt gagttaaaaa
    19981 agaagcataa ttatgaacag taaagtttct aatataacaa taattcgaga agctttgcaa
    20041 aatcatgctg ccaatgaact ctctaaacat ataggattaa atctaagtac tataaaaggt
    20101 taaaaagtga agaatattta atagaaaaac taaatttact tgctgctttc cccttttcca
    20161 ttaatacaac aatcagagag tgtctttttt tcgaaaaaat tagaataaat aaaagacacg
    20221 tagttttttt atctacatgt cttccatcga ctacaagtta tcatttctca aaacgtattt
    20281 agcttttaat tgattaatcg tttcacgttg tctacacatt gcctaattaa gattttctta
    20341 ttagaagcat caatcccgca ataataccta aaactccagg aattacccac aataatgtta
    20401 aaagaaaaaa tggaataata gataaaatga gtaaactaat accatagacc actgtttttt
    20461 gattttttct tactaaaaaa cctattatga aaatcattat cgaaaaaact agggtaattc
    20521 ctccaaataa aacaacattc ccgcttagat tgactaacat atctatatcc ttactggtta
    20581 gttctgtagt atttaaagta gttgaatcaa tagaagatag aaacatacca cccatcaatg
    20641 ctaaaagact acataaaatc cctgttattc cactaattaa aatcaaaata aactctgttt
    20701 ttctcttatt catttaattc tctccagatt aagtgtttta gaattagaaa ttttttgacc
    20761 atagttaata gcttctaatg aacgaataac aaccactgac gtgttagaaa aataatcccc
    20821 aatatgttgt ttcttgggcg tgaaagcagc caccaaatac ccaatttgaa atacaaaatt
    20881 ttttaatata aacctacata tacactcacg aataaagata gtttgccaac ttagctcttt
    20941 ttcctcaaag ctcactactc ttatcccaaa aatcattttc ccaattgttt gtcctgaatt
    21001 cagcttagtc aaaagtacaa aataggttaa ataaatagct aatgacgcta taccataaaa
    21061 agtaataatg gatttgtcag attccagtcc catgattttg taaaagagac ctatagtagc
    21121 atgggtgatg atgctaatac aaattaaatc aataagaaaa gcaaaaaatc gtaaccaaaa
    21181 tcccgcaaat acataattag gcaaagtttc aatgccactc ttcttattca ttttatagcc
    21241 ctccatagta atacattggt tttggagtat cagaaaatcc aagtttttca aaaactgaaa
    21301 ttacacgatc tgatgtagtt gcctttagcc cttgccattc agcaatctta ttacctaacc
    21361 aagaagaagc aaagccagtt gtgtcatttt tatattctat aaccgtcgca tcagttaatt
    21421 tcttctcttt ttttagggaa tctaatgcat cttcagagta accaatttga tccaccaacc
    21481 cattttctac tgcttggtta ccatcataaa ttcttccatc cgcaagttct ttcactgcat
    21541 tagtatccat atttcttcct tttgctacaa cattgacaaa acgatcataa gcactcatca
    21601 caaattcctg tataacttta ttctcttcct ctgaaggttt gtgttgaggt gacatcatat
    21661 cttttaatgc accactttta tacgtcgcat cagttacgcc aagtttttct aataagccag
    21721 aataatttaa accagaaata atgacaccaa ttgatccagt tgttgtttct tccgtagcaa
    21781 atattttatc tgaaccagca gaaatgtagt accctccact tgccgctgta tttttaaatg
    21841 cagtatagat aggaatatct agctttttaa tttttgccat ttctttagca atctcagcac
    21901 tttcatatat tcctccccca ggtgaattta cttctaataa cactccctta accgctttgt
    21961 cttcttgaat tttctttagc tgtgttaaaa aattctgatg gttatattgt tccctactaa
    22021 aaagattgct ttcacctgta tctgcaataa ctccattgac ggatagtttg acaatctttt
    22081 tatttgatgc gccttcttct aacgtttctt ctgtgatttc gttagatccg taaaaaatct
    22141 tatttattcc tgttagggtt gtatttgatg cttcctcttt atcttttcct ggaattagcg
    22201 cgacgataat ggatagtaac aataatccgc acgctactcc cacagcaatc catcttcttt
    22261 tattcatata aactcctcct atattcttag taaaaataat tattttttat ttagaaacac
    22321 atcgacaatt tgttgccaat atgttttttc tcctacaatt aaagacaact ctccagttaa
    22381 tccataacga aacggaaacg attgagttgt ttttaacgtt cctttcactg cataaaaaac
    22441 acctttctca gtggcagtag aattttctga aatttcatct aaagttccgt cgatcgtaat
    22501 cggagcccca cctttttgat ccaatttaaa atgaaccttc atcccttctt taatataggt
    22561 actttcattc gcaggtaaaa gtgctgtaaa tttcattttt gatttttcgt ggatcggata
    22621 aatttctgca agcactgttc ctttggctag ttctgcttgt ccctttgttt cttcatttaa
    22681 atgaaccgtt ccagatacag gagcttttag tattcctttt gaaagttgat cgtccaaact
    22741 tttgataact gactggttct tctcttgttt ttcatttagc tctgtaactg tttgttttac
    22801 agttgttatt gcttgttcta gctcttgctt tcctttttcc gtttgactaa ttctgtcatt
    22861 ctcagaagta gttggtttaa ctaatttagc tttttctgac tgatactgtt ctacttcttt
    22921 ttttagttgc tcaatttgtt catttatgct tgctgaaatt gtcagtttca cttgattttt
    22981 ttgatcatca gaaacattat ttagttgttc ttgccaattc tcatagtttg ccatcatttc
    23041 ttttgaaaaa tcttttaatg attgattatt actccaagct acctgtactt gttgccattc
    23101 ttgtaattta ctatctgaac tctcaatttg tttttctagt tgtctttttg tcttttcgta
    23161 tacttctaat tgcttttgat catttaattc actttgcttc aaagcgtagc ggagtgattc
    23221 tttttctgac aacatgctct ttaattgatt actgtagcca aaactgtcat ccgttgaaaa
    23281 caaatttttt cctttactta tactttcaat aaatagctga gccatcttta tttgttgagt
    23341 aatacgttgg ttttcttgtt ctatctgagc cttttcattc tctattaaag aacaatccaa
    23401 tctaaccaac acatcgtcct tatgaacaaa ttgattttct tttaggaagt tttccattat
    23461 tttagcttct aatggcactt gtaacttctc tattttttcg gggttcaatt gagccgttgt
    23521 ccgaataaca acctcttttt tagcaaaggt taaaaacaat ccaataatac ataaaaaaag
    23581 aattacaggg tataacaccc aacggtagaa gctatgatgt tgtttagtat agatactaga
    23641 atgttcgaac caattattat tctgcataaa ttgtttccct ctcctagatt tcccataatt
    23701 tttgatagat accatcggca aaacgaagtt catcgtgcgt tcctttttct accaaatgcc
    23761 cttcatggag aactaaaatt tgatcacatg cttttgctat tggtaaatga tgcgcaataa
    23821 aaataatcgt tttttctttt aaattgagga gataattcat aattgcatgt tctaacaagg
    23881 tatctaatcc actagttgct tcatctaaaa ttaatatgtc cggatttttt aataaagccc
    23941 gtgctaaggc taatcgttgt cgttgccctc ctgaaagatt atttccacct tcttccaaca
    24001 atgtctcgta acgtaatggc tgttgattaa taaattcatt tagttggact atctcacaaa
    24061 cttctattat ttgttcgaaa cttggtgggc tatctaaacc gaatataaga ttctcaatga
    24121 ttgttccact aaagaaaaat gactcttgag gcaaatatgt cactcgatcg cgtaatatct
    24181 gaaaaggaat gtctaagtga ttaatgtttc cataatggat cgatccttct gatgcttcat
    24241 aaaaacgaac aaataacttt gcaagagttg attttccaga accactaact ccaactatag
    24301 ccgttttact gtgcgaagga attgtacatg aaatttcgtt caacgttggg gccttcatgc
    24361 tatacgagaa tgaaacgttt tttacagtga tatcttgttg aaataattgt tcagaaagca
    24421 tatattcaaa agactggttc gatttttctg aatcaatcgc gaaaatttca tttaaacgat
    24481 tatttgcaac ttgagccgtt tgcattttca cttgtaaatt aataatgttt tgtaaaggat
    24541 ctgtcaaaaa tactagtaaa gcattgtatg tgataagttg acctagacta attctattat
    24601 ccataacaaa ataagaacct agccataaaa ttaatgcact gctaattaat tgaatcaaat
    24661 gtttaattcc ttgttgaata ttatcaagcg taaccgtacg aaatgatttt ttcattaatt
    24721 taacaaattc atggtctata cggttatata ctttctcttc accgctatat gctttaattg
    24781 tttctattcc tttaagactt tctatgatac tagaatttac agctgcaccg gctgccattt
    24841 cttccctgtt cgatttttca tagcttttca cgaaagcgaa tattgcaact acataaaaag
    24901 gcaaagagca tagagtgatt aaaaacaacg tactattctg aatagctaac gtaaccccaa
    24961 caagcaacac cataccaata tctaaaaata ttgataacgt agcacttgct aaagcatcaa
    25021 taatcttact ggcatcaaga aaacgagaaa taatttcccc tgattttctc gtagcaaaaa
    25081 aattcattgg taaagttaac acatgtttga aatactgaag cataattgcc atactcattc
    25141 gctgtcctaa aataataaga agataactac gactatattc aaacaatacc cgaaataaat
    25201 agacagcgat caagccaatg gaaattatat ttaaagttga acgtgcttga ttagggatga
    25261 aaaaatcaag aataccttga aaataatatg agcttcctat gccaaaaaac gtaatgaaaa
    25321 tcgatgctaa aacgatgtgg aatactaatc ctttttgttt ccaaattata ggcaaaaaag
    25381 aacttaatcc agctactttt tctttaatag gaatataagt ttctctaggc ataggtaata
    25441 aaagaatacc tgtccattct ttttgaaacg cttcaatcgt ttttctattt tttccattag
    25501 cgggatctgc aatccatagt acgtttccct tcgttttata aattacaacg tagtgcatat
    25561 agctgttatc aaccaatata tgtgcaatta atggtaagat aagatctctt tctttccaga
    25621 tctcactatc tgcttgaata gccatacaat caaaagacaa tttttcaaat gtctttttca
    25681 atccaaatgc tgaagtaccc tctaaatcag tcccagatag gtcccgtaat ttatgaatcg
    25741 ggatatcagt tttaaaatat tttaaaatca tcgaaaggca agcaacacca caatcttttt
    25801 catcttgttg ctgcacaaaa ggaaatgatt ttatcactta tctaacacaa ctccttctaa
    25861 aaaattttta tagaaaaatt ctcaa
//
LOCUS       DAXLPC010000034        24842 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.034, whole genome shotgun sequence.
ACCESSION   DAXLPC010000034 DAXLPC010000000
VERSION     DAXLPC010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.034"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(301..864)
                     /locus_tag="ACF3UE_001353"
     CDS             complement(301..864)
                     /locus_tag="ACF3UE_001353"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFD3634774.1"
                     /translation="MITVVHKERQEKSSSDVRLWVYLGSISTKIQYGYTDSAKKQGNV
                     KFLRITDIQEGRVNWSSVPYCDISNSKLIDLRLEENDILIARTGGTMGKSFLVKEISE
                     ESVFASYLIRIRLVEKLLSEYVDCFLDSPLYWKLLEKISYGTGQPNVNGTNLSKLLIP
                     LPPLEEQQRMTTKIEMIRRSIRRINFE"
     gene            complement(879..1922)
                     /locus_tag="ACF3UE_001354"
     CDS             complement(879..1922)
                     /locus_tag="ACF3UE_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634775.1"
                     /translation="MTQRVAIMILVLLVIGLLVYYVLKFKHWKQQRIHQDIEKKLKRY
                     PIVQAAWEKAEAKQYNIPGLTETRMVVPETGENEVCQWMTPQGLAFSQDFVFISAYCY
                     DHQHHSIIHVLDRETGQPIKLLILPKRPHVGGLVYDTKRELLWLTITGSATGRVAALR
                     LIDILADTSEETGQPIAYWLTTDLSEIPQASYLTQNNDQLVSGNFTLKGEGQLTFYLL
                     PTIAEMKTAIRRKDKIQPTVTMSRKTSDKIQGVAFYGHYLLASRSYGPYTSELLVSER
                     DSPSRILKRIKFPPYLEQIVVVEDRLAVLFESGAAAYREKANPVLANVLLLDLATLLH
                     ANKRPKKIAATKK"
     gene            complement(2055..2459)
                     /locus_tag="ACF3UE_001355"
     CDS             complement(2055..2459)
                     /locus_tag="ACF3UE_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFD3634776.1"
                     /translation="MKKMYETAMINRGGRDGEVEAPNGSMHMKIDRPGIHSEGTNPEQ
                     LFAAGYASCFNGAVQHMLEENNLESDSEVKARVSLFQLEDGGYQIGVVLEVSLPGLEK
                     DQAEKIAEEAHAFCPYSKATRGNIDVEVTIVE"
     gene            complement(2659..2907)
                     /locus_tag="ACF3UE_001356"
     CDS             complement(2659..2907)
                     /locus_tag="ACF3UE_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005225422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3634777.1"
                     /translation="MHWLWVLIVGAIIGLIAGAITNKGGSMGWIANIVAGLVGSAIGQ
                     ALLGSWGPQLAGMALIPSIIGAIIVVAVVSFFLGRSRG"
     gene            complement(3542..4489)
                     /locus_tag="ACF3UE_001357"
     CDS             complement(3542..4489)
                     /locus_tag="ACF3UE_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005470715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD3634778.1"
                     /translation="MYSYYKIEKNQIRESSEEDYNWLVVKHGNEEEKKELLTLFDLPE
                     DIFIGSDEPEEVSRLEHLRDTKLNNPFLYTLIDLSSNHQERIEKRLEPVTFILSKGLM
                     ITYVSRESNLVERLIEKHGSELRHFEDIIAFATLMIYTHYINGLKEIKKQIDQLDAAA
                     RKTTENNELFNLADTERDMVYLDHTLKDQNLTVNHLMERKEFLDKLDNESLVYDIKLR
                     QKFANKLVTIYRDLLETIGGLFSDMMDNNLNHLMKYLDSAALVVAVPSLIAGLWRINT
                     GGLPGKDNTIGTILVFGLAVLVGILTAVYLSKKDFSKTK"
     gene            4681..5508
                     /locus_tag="ACF3UE_001358"
     CDS             4681..5508
                     /locus_tag="ACF3UE_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFD3634779.1"
                     /translation="MFLHQKELQFEAKPDKPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMKKDPAIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDLLSVLLARDSYHQNLWAQAVKELEEKEGTILVPSTFPRNEERLDIAY
                     DFYNFSEGDQSKEGSWGKGKALDGEGEYQWLSTPKVEGKAPKLDPVTPKMYGTPPEK"
     gene            5650..6489
                     /locus_tag="ACF3UE_001359"
     CDS             5650..6489
                     /locus_tag="ACF3UE_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003125793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFD3634780.1"
                     /translation="MKAPLLTLNDGNMRPAVGIGTYQIRGGEGLSQLQAAIADGYRLI
                     DSSTNYDNEGIVGKAIRRSGVPRSEFYITSKLPGKYHGYDDALTSIQESLARMGLDYF
                     DAFLIHWPLPKRGKYIEAWQALVTAQKLGLIRSIGVSNFEPEHLDAIIEATGVTPAIN
                     QIEIHPYWVQEQMVAENRKRGIITEAWSPLGRGSAALKESIITDLANKYQKSAGQVIL
                     RWHVDRGILPLPKSRNLSHQRENLAIFDFELTEEEINAINRLNKEDGRIEGQDPNEYE
                     EFE"
     gene            complement(6741..7478)
                     /locus_tag="ACF3UE_001360"
     CDS             complement(6741..7478)
                     /locus_tag="ACF3UE_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008379144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar isomerase domain-containing protein"
                     /protein_id="HFD3634781.1"
                     /translation="MYQYVDKIHALLETVEKKEQHAIDEAIRLLTTANLEKHSIYIFG
                     ASHAGILAEEMYYRAGGMMTINAIFGRELMLDRSPITFTSKMERLEGYGTALAEIQPF
                     KEGDVLILHSVSGRNPVIIDLALAAKEKGVKIIALTNKTYSQSVTSRHSSGLRLFEVA
                     DLVIDNHGEIGDAGCQIKGMDQKVGPTSTVIGATILNTIIVEVCQQLKQAGIDYPPIF
                     YSANMDGGDELNQSLFEQYKEAIHYQL"
     gene            complement(7480..8730)
                     /locus_tag="ACF3UE_001361"
     CDS             complement(7480..8730)
                     /locus_tag="ACF3UE_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFD3634782.1"
                     /translation="MSFVTDHILKNPPVLLGLIAMIGLIVQRKPFAEVVKGSLTAAFG
                     MVALTAGVNMLTGTIAPINTAVQTQLGVQVADGLSDVTFTAEYGGTVGLAMFFGLILH
                     LLIARFTPVKTIFLTGHMLWWFPFVIVAGGVEGGMSGIPLLILGAVLSACYWSFMPWI
                     MRKYVWDATGDDSFLIGHPTGILSMVSGFVAKRVGNKEKSTEDLKVPENLSFFREISI
                     TGALVMFLMNIVVGIIAPVLVPEGGNLVMFAVQAGLNFGAGLLIMLYGVRLLINQIIP
                     AFQGIAEKVVPGAKPAFDVPILFNYRPNAVIIGFIVAMITSTILVIIVNTTNVFGILI
                     VPLVITSFFECGGAAVIGEGQGGLRGAVIGTIAASFVMVLLVGVSAVLFSTTIQNWIL
                     IFGGNDISLWGIIGRGLGSLFGGI"
     gene            complement(8733..9014)
                     /locus_tag="ACF3UE_001362"
     CDS             complement(8733..9014)
                     /locus_tag="ACF3UE_001362"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3634783.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIDKVIKELGLKATAENTDLSTAKA
                     TPADVYFTSHELLNDLQASVKAPVYPIKKYMDVAEVKMQMEKFLAEREG"
     gene            complement(9027..9458)
                     /locus_tag="ACF3UE_001363"
     CDS             complement(9027..9458)
                     /locus_tag="ACF3UE_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3634784.1"
                     /translation="MINLKKLLPEDHIETTNQILTWQEAVQLASQPLLNEKAIDQQYV
                     ANMIHSVEENGPYMVLADYFALMHARPGEGVFHQGMSLLVTKNEIDLAGKSVRIFLVL
                     AAKDNQSHLESLQEIMEVFMDQEKYQLILNGDKEQICQLFQ"
     gene            complement(9455..11092)
                     /locus_tag="ACF3UE_001364"
     CDS             complement(9455..11092)
                     /locus_tag="ACF3UE_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003125786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3634785.1"
                     /translation="MKNNYSLIEDRRMQIFKRLINGEHLSYQQLSDEYYVSRSSIAKD
                     IAYLKTLFVKENLLLRFDNSGTYFQGSESQIQRMLKRFILLTVEHGENLSVLTNVSLF
                     EKINAAFRHSITEKQMEIPESYIQSIVVSILLIVERSNQANQLDIEEKRQFGKLFLEF
                     DKYPLIYELLKEIEEQEIYHFSSKEVQYLTYLIVGSGLRFFMKNESIPFSFRGKVRNL
                     IQKVSEGIQIDLTQDSRLEEDLTIHLYQLFLRIEAQTTVVNPLLDEIKQHYPALYGVV
                     WFSLDDFLKAYHIGISEDEIGFVSIHFQAAVERMRQLNKIVFVCPNGVGTSSFISAKI
                     RRILPNVDSIETASVAKLKEMDISAIDFIISTIDLPDVSKPVVRISPMVTNRDMKRIM
                     NHYIDLIIDNEPIADKVKILQDTRMLIAPKIYFERFETKEQALDFLISQNDFSSENQR
                     TDFQRSVLEREALQSTYLDNGFAIPHGNPEFVSKTTFSVLILDRPVDWGNQKVDIIVL
                     LMIREDEAQEVEPVMKLIMQGIEDKEWFISKMLEVKS"
     gene            11306..12199
                     /locus_tag="ACF3UE_001365"
     CDS             11306..12199
                     /locus_tag="ACF3UE_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HFD3634786.1"
                     /translation="MKWRGGRQSSNVEDRSGRSAGSGGKIMVGGGIGTIVIAVLFFLF
                     SGGDLNSVTDILGGGQAANYQTENVASDEYTEEKEFSAVVFGHLEDYWNGVFEAEQTT
                     YQDPKLVLFTGSVQSACGNATSQVGPFYCPADQNVYLDLSFATELSQKYGASGDFAMA
                     YVIAHEVGHHVQNELGITQQLDKIRQQVSEKEYNQYSVRLELQADYLAGTFAKYLQGK
                     TYNGQPILEAGDIEEAITAANAIGDDTLQKEYQGYVVPDSFTHGTSKQRVEWFNRGFK
                     YGDLEHGDTFNEKNLDLVYGS"
     gene            12541..12622
                     /locus_tag="ACF3UE_001366"
     tRNA            12541..12622
                     /locus_tag="ACF3UE_001366"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12574..12576,aa:Leu,seq:cag)
     gene            12777..13280
                     /locus_tag="ACF3UE_001367"
     CDS             12777..13280
                     /locus_tag="ACF3UE_001367"
                     /inference="COORDINATES: protein motif:HMM:NF024954.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3634787.1"
                     /translation="METERQIRELEKAMNTTDNRRLYERFLAVKLVLEGHTRKEAGHT
                     IGRDEHTVSHYVKNYCHNGIQGLVSKKQSGRPSRLTDEQEAELVQIVAYHTPEEVGFK
                     SRANWTLAIVCDLILREWSYGYTQKGVADLHNFPPRYYEYPGGVIACVTAYANLQHRS
                     KWLSSKK"
     gene            complement(13493..14248)
                     /locus_tag="ACF3UE_001368"
     CDS             complement(13493..14248)
                     /locus_tag="ACF3UE_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3634788.1"
                     /translation="MDFEQNVRLNFDLLSDNEKDMVFFIRTHKAQVVHMSIVELGEQL
                     LSSKSSVLRLAKKLGFRGYSEMKYSLEQSIVQSVIPPTDLIALLKDEINRTFQLADQT
                     NFQPILEQLKAAKTVVVYATGFTQNNFSKDFVNDLILSGRPAMLISGETNFEMLSHTL
                     TKDDFVIVTSLSGETPSIKSTIKNLNMNRIPLCGVTELGKNFLSEHSDFLLYYETREL
                     PSNLIEGSRSMIGLNILLSILSRKYREFILFDE"
     gene            complement(14355..16025)
                     /locus_tag="ACF3UE_001369"
     CDS             complement(14355..16025)
                     /locus_tag="ACF3UE_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFD3634789.1"
                     /translation="MNEWWKSSVVYQVYPQSFKDSNNDGIGDLMGIVEKLPYLAKLGV
                     DVIWLTPIFDSPLIDNGYDIRDYEKISENYGTLEDFKRLLEQAHQLNIRVILDLVVNH
                     TSNQHAWFIESQKNKENPYSDYYIWKDPKEDGSAPTNWGSTFGGSAWEYVESRKQYYL
                     HCFAKEQPDLNWENPKVRQSIYKMMKKWFDLGIDGFRMDVISLISKHPDYPDAPNSMP
                     YTKSYYVGASNGPRVHEFLQEMNREVLSKYDSLTVGETPNTNSRQAQLYTFPERKELN
                     MVFHFDHMHLDYGKYGKFSDVRFKLSDLRATLSEWQEALSDGWNSLYWSNHDQPRAVT
                     RFGDENEYRIESSKMLGTLLHMMKGTPFIFQGEEIGMKNVPFSSIDEYQDIETNYFYK
                     KMKEEGESDEYIKRAIYLKSRDNARTPMPWDHSKGYGFSNSDPWISFSPDNQQINVED
                     ALKNPNSVFYHYQKLISLRKNYPIIQHGTYKLINENDSAVFGYIREYKNELLVVICSF
                     SKESVPYELPKSLQGRKGVLLLSNYEQSPSELEDKFILRPYEALVYHI"
     gene            complement(16029..16448)
                     /locus_tag="ACF3UE_001370"
     CDS             complement(16029..16448)
                     /locus_tag="ACF3UE_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3634790.1"
                     /translation="MKKIIFASHHNLAVGLKDTVQYILPNVGEITAIAGYIDNSPIEE
                     KINEVMVRDNEDTDILIFTDMLGGSVNQAFIKYINQPNVYLITGMNLPVVLTILLNTL
                     NKRLTDNHIREAIQEAQDQLVYVNDYLKNIVVDEEDE"
     gene            complement(16461..17270)
                     /locus_tag="ACF3UE_001371"
     CDS             complement(16461..17270)
                     /locus_tag="ACF3UE_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3634791.1"
                     /translation="MNNEGNKLSKKDIRRAAFRYMFMACNIFNYENQQGPAVVYGLEK
                     ALRKIYPNDEDYRASLNNHFKYFNTTTWMANLLLGASLAMEEKDGVSSLDAVQSFKTG
                     MMGPLAGVGDTLVWVLYPTIMGSIAAYMGLEGNPTGAIIWLCLNLFFLFFRFKLFSIG
                     YTSGLKLVTALGSKLSIFTESASIMGLTVVGALIPSVVKMNVAVVFQSGKVKLPIQTE
                     ILDKIMPALLPAVLTIIVYKLIASKKMTVIQIIFSVIIFALILSFFGILKV"
     gene            complement(17263..18063)
                     /locus_tag="ACF3UE_001372"
     CDS             complement(17263..18063)
                     /locus_tag="ACF3UE_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3634792.1"
                     /translation="MEIIQGILIIILAVWVVLDQQGLVITTWFPIMIALFAGLIMGDM
                     TTAMVIGGTFQLMALGVANIGGSSVPNWGLAALVGIYVAIRTTNNIEEAKAVALAVGV
                     PVGMLGIQLDVLAKILNTYVTHAAQKAANKMDFKKMNQILWLGPVIFGLSTAIPTALC
                     VVFGDRIVRLILDFVPKWFTDGLSIAGSMLPVVGIALLLQVMPVKKYMTMLLIGFVLS
                     AYLNMPILGISIVGFALAYYFFTTEIKKAETASPVAANIVDEGDDFDE"
     gene            complement(18078..18554)
                     /locus_tag="ACF3UE_001373"
     CDS             complement(18078..18554)
                     /locus_tag="ACF3UE_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFD3634793.1"
                     /translation="MGLVLARIDQRLIHGIVVTQWAGATKAKRLMVVDDQVSKDDTQK
                     AAMRMSKPAGTGMSIIDTDTAIINFKLGKYDSHNVLMIVKEPSTLVKLAENGIDIPKV
                     NIGIMFDGEGKQTVKKMVSVDEQEIADLKKLEAMGIPVTFHFVPSDPEEPLDVRIK"
     gene            complement(18949..19428)
                     /gene="rlmH"
                     /locus_tag="ACF3UE_001374"
     CDS             complement(18949..19428)
                     /gene="rlmH"
                     /locus_tag="ACF3UE_001374"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFD3634794.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAHISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            19857..21143
                     /locus_tag="ACF3UE_001375"
     CDS             19857..21143
                     /locus_tag="ACF3UE_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFD3634795.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTTSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSGF
                     GGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKDG
                     TKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYANS
                     VTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSKI
                     ASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQE
                     QILKIPSSVTNGVIVTNVQTATPAEKAGLKKYDVITKIDDKEVSSGVELQSALYKKKV
                     GDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(21318..21923)
                     /gene="ytpR"
                     /locus_tag="ACF3UE_001376"
     CDS             complement(21318..21923)
                     /gene="ytpR"
                     /locus_tag="ACF3UE_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFD3634796.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(22128..22592)
                     /locus_tag="ACF3UE_001377"
     CDS             complement(22128..22592)
                     /locus_tag="ACF3UE_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFD3634797.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(22614..22934)
                     /locus_tag="ACF3UE_001378"
     CDS             complement(22614..22934)
                     /locus_tag="ACF3UE_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFD3634798.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(23077..24156)
                     /gene="pepA"
                     /locus_tag="ACF3UE_001379"
     CDS             complement(23077..24156)
                     /gene="pepA"
                     /locus_tag="ACF3UE_001379"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFD3634799.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            24356..24706
                     /locus_tag="ACF3UE_001380"
     CDS             24356..24706
                     /locus_tag="ACF3UE_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFD3634800.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
BASE COUNT         7457 a         5210 c         4420 g         7755 t
ORIGIN      
        1 aatcatttgt ttaaaatttt cttcatatcg ggtcataaaa attcatcctc tcgtagataa
       61 gtttaattta ttcttgtctc tacgaaaagc tgtctaagat ttgatactaa caccaaactt
      121 cataaagtaa atcttttata catttccact tctagatggt cattcatgtt agaagaatca
      181 aactattttt ttactgtcgt aataatatta aaacactaga acaaatcaat taaattccat
      241 aaaatataaa taatagacct agcatcatct ggtataaaat ggatgctagg tccgttatat
      301 ttactcaaaa ttgattctac gaatagatct tcttatcatt tctattttag tagtcatgcg
      361 ttgttgttct tctaaaggtg gtaatggtat aagtagttta gataaatttg taccatttac
      421 atttggttgc ccagttccgt aagaaatttt ttctaataac ttccaatata atggcgagtc
      481 taagaagcag tctacatatt ctgataataa tttctcaact aacctaattc gaatcaagta
      541 agaagcaaaa acagattcct cacttatttc cttaaccaag aaactttttc ccatagttcc
      601 tcctgtcctt gctatcaaaa tgtcattttc ttctaatctt aaatcaatta gtttagaatt
      661 actaatatca cagtaaggca cactggacca atttacacgt ccctcttgta tatctgtgat
      721 tctcaaaaac ttaacattgc cttgtttttt cgccgaatct gtatagccat attgaatctt
      781 agtagaaata cttcctaaat aaacccatag tcgaacatcg ctagatgatt tttcttgtcg
      841 ttctttatga acaacagtga tcatcttgag ttgtccgact attttttagt tgcagcaatc
      901 tttttgggac gcttatttgc atgaagcaac gttgctaagt ctagtaataa aacattggct
      961 aacacaggat tggctttctc gcgatacgct gcggcgccac tttcaaacaa tactgctaga
     1021 cgatcttcta caacaacgat ttgttccaaa tacggtggaa atttgattcg ttttaggatc
     1081 cggctaggag agtcccgctc ggacactaag agttccgagg tataaggacc ataagaacga
     1141 ctggctaaga gataatggcc ataaaaagcc acaccttgaa tcttatcaga tgtttttctg
     1201 ctcattgtca cggttggttg gattttgtct ttgcggcgaa ttgctgtttt catttcagct
     1261 atcgtcggca atagatagaa agtcaactgt ccttcacctt ttagtgtgaa gttgccagat
     1321 accagttgat cattgttttg agtcaaatac gatgcttgtg gaatctctga gagatcagtt
     1381 gtcagccaat aagcgattgg ctgtcccgtc tcttcagatg tatctgctaa gatatcgatc
     1441 aaacgtaaag cggctactcg tccagtagca gatcctgtga ttgtcaacca taaaagttcc
     1501 cgttttgtat catatactaa gccccctaca tgtggccgtt taggtaaaat cagcagtttg
     1561 atcggctgtc ctgtttctct atccagtaca tgaataatag aatgatgctg atggtcatag
     1621 cagtaggcag aaataaacac aaaatcttga gaaaaagcca acccttgcgg cgtcatccat
     1681 tgacaaacct cattttcgcc ggtttccggc accaccattc ttgtttctgt taatccagga
     1741 atgttatatt gttttgcttc agccttttcc caagctgctt gaacaatagg ataccgtttt
     1801 aacttttttt caatatcctg atgtatccgt tgctgcttcc aatgcttaaa ctttaggaca
     1861 tagtaaacaa ggaggccaat gaccagcaac actaaaatca ttattgctac ccgctgtgtc
     1921 atttttttgc ctccttgttc tattcgatca atcgtacata taccgctatt aattaccgta
     1981 actacatgtt tcttttacta gcgtttcttt ataggatctt tcataatctc atttatagta
     2041 acattaagaa tcccttattc tactatagtc acttccacat caatattgcc tcttgttgct
     2101 ttagagtatg ggcaaaatgc gtgggcttct tctgcgattt tctctgcttg gtccttctca
     2161 agtcctggca aagaaacttc taaaacaacc ccgatttggt agcccccatc ttctaattga
     2221 aataaagata cccgtgcttt gacttcagaa tcagactcaa gattattttc ttccagcatg
     2281 tgttgaaccg cgccgttgaa gcaagatgcg tatccagccg caaaaagttg ttccggattt
     2341 gtcccttcac tatggattcc tgggcggtcg atcttcatgt gcatacttcc gtttggtgcc
     2401 tcaacctcgc catcacggcc tccacgattg atcattgctg tttcgtacat ttttttcatt
     2461 gagatcatcc tttctttcgt cgttctatat taagtgtaac gagtattttt taatctgaca
     2521 aaggtaatgc ttgcattcgg cgacatcagt tagacaacat cgatgatcag tgatagaagc
     2581 agtttatcta tacaaaaaaa gaagcagcga aaagctgctc cttaagataa taggtaaaat
     2641 tgctgatata tttgacgatt aacctcttga acgtcccaag aaaaatgata ctacagcaac
     2701 aacgatgatc gcaccaatga tagaaggaat caaagccatt cctgctaatt gaggacccca
     2761 gctacctaac aatgcttgtc caattgctga accaactaaa cctgcaacga tgttagcgat
     2821 ccatcccatt gatccacctt tatttgtaat tgctccggca atcaaaccga taatagctcc
     2881 tacgattaat acccataacc aatgcataat tttctctttc tttctgtgaa atatttatta
     2941 cacatattat gttacgcttc ttcttaaaaa tacacaaaaa ttttgctctt aaaaaaacaa
     3001 aaaaaattta aaacgttgtt atattaagga taagtcaact tttttggaat cgttaacact
     3061 cactgcaaga ggtcaaaaaa actgccgcag ctctttgaaa gcgtttcgat cagcaaaaag
     3121 ttattttctg ataaagggta cctagactat gtacgatttt ctttcattgt ctgctttcaa
     3181 ccgtcatctt ccctatgaat aaaagcaatc aaagaaacct gattgtcgta cacacctcat
     3241 tcactacatc cttctgatga aacatcaaaa caattggcat tcctttgatt ctgccttttg
     3301 tatttgaaac ctgcttcccc tcactatgta aaaggattat gagaaaaagc aacgatagaa
     3361 gtgagcgtat gcaatagcga gtaaagtaaa atataaattg ttcggattgt accccggcct
     3421 ttcttcttaa tatttttcat ttctcgcttc tcccctctgc ttattggaca gtcttcgcga
     3481 ttgtgaagtc acgaaaaaaa gcaactttgc ccagcgttca atgctagaca aagttgcttt
     3541 tttattttgt ttttgaaaag tctttctttg aaagatagac agcagtaagg atgcctacta
     3601 agacagctaa cccaaaaact agaatcgttc ctatcgtgtt atccttccca ggcagtccgc
     3661 cagtgttgat cctccaaagt ccagcaatca atgatggcac tgcaaccact aatgctgctg
     3721 aatctaaata tttcatcaaa tggttcaaat tattgtccat catatccgag aatagaccac
     3781 cgatggtttc caataaatcg cgatagatcg tgacaagctt gttggcaaat ttctgtcgca
     3841 gtttaatgtc gtaaactaac gattcattat ctaatttgtc taaaaactct tttcgttcca
     3901 tcaagtgatt cactgtaaga ttctgatctt tcaacgtgtg atccaaataa accatatctc
     3961 gttctgtgtc tgccagatta aatagttcat tattttcggt tgttttacgg gcagccgcat
     4021 ccaattggtc gatttgcttt ttaatctctt tcaacccatt gatatagtgg gtatagatca
     4081 ttaatgtggc aaaagcaatg atatcctcaa aatgtcgaag ctcacttcca tgtttctcga
     4141 tcaatcgctc aacgagattc gattctctag agacataggt gatcatcaat cctttggaaa
     4201 gaataaatgt gacaggttca aggcgttttt caatgcgttc ttgatgattt gaagaaagat
     4261 cgatcaatgt ataaagaaac ggattgttta atttagtgtc tcgtaaatgt tctaatcgag
     4321 aaacttcctc tggttcatcg gagccaataa aaatatcttc cggtaaatca aaaagtgtca
     4381 gcagctcttt tttttcttct tcatttccat gtttgactac caaccaatta tagtcttctt
     4441 cggatgattc tctgatttgg ttcttttcga ttttatagta cgaatacatt ttgcctctct
     4501 cctttaactc cttcacttct cttcaactat ctaatggcga ctgctttttg tcaagaaaaa
     4561 gcgctatttc aacggttttt attaatacgg aaataaagca agcgtttgat cagaccattc
     4621 taaataaacg tgagagaata tttttgggcc caataaaaat cattttagag gaggacaact
     4681 atgtttctac atcagaaaga actacagttc gaagcaaaac cagacaaacc aaatccatta
     4741 attgcgaagt atcttcaaga attgatcggt ggccagtatg gcgaaatgag tgtagcaatg
     4801 cagtatctct tccaaggttg gagctgccgt ggagaagaaa agtacaaaga tatgttgatg
     4861 gacattgcga cagaagaaat tggacacgtt gaaatgcttg ctacaatggt tgctcgttta
     4921 ttagaaggtg caccggtaga agatcaagaa gccgcaatga aaaaagaccc agcaattggc
     4981 gcaattatct ctggaatgaa tccacaacat gcgatcgttg ctggcttagg accacgtcca
     5041 gctgacagtg tcggtaatcc atggagtggc gcttatatca ttgccagcgg taatttactg
     5101 gcagacttcc gtgccaattt aaatgcagaa tcacaaggac gattacaagt cgctcgaatc
     5161 tatgaaatga ttgatgaccg tggagttaaa gacctcttat ccgtgctatt agctcgggac
     5221 agctatcacc aaaacctttg ggcacaagct gtcaaagaac ttgaagaaaa agagggtaca
     5281 atcttagtac cgagcacttt ccctcgtaat gaagaacggt tagacatcgc ctatgacttt
     5341 tacaatttct ctgaaggaga tcaaagtaaa gaaggctctt ggggaaaagg aaaagcactt
     5401 gatggtgaag gtgaatacca atggctttct acacctaaag ttgaaggcaa agcgccaaaa
     5461 ctagatcctg tcacaccaaa aatgtatggc acgccacctg aaaaataaat tgatcgaaac
     5521 gaataaaaag agcaatgatt ccattcacaa gaaatcattg ctcttttctt gtcttattga
     5581 gcaagttggt taccttaaag ctaaaaaagc gttagagtag aatgtataag aaaaaggagg
     5641 aatcattata tgaaagcacc tttacttaca ctaaatgacg gcaatatgcg cccagccgtg
     5701 ggcatcggta cctatcaaat tcgcggtggc gaaggcttaa gccagttgca agcagcgatt
     5761 gcagatggct atcgtttgat tgattcgtca acgaactatg acaatgaagg aatcgtcggt
     5821 aaagcgattc gccgatccgg tgtccctcgt tctgagtttt atatcacctc aaaattacca
     5881 ggaaaatatc atggatatga tgatgcactg accagtattc aagaatcgct ggcgcgcatg
     5941 ggattagatt actttgacgc ctttttgatc cactggccac tgcctaaacg cggcaagtac
     6001 attgaagcgt ggcaggcgtt agtgactgcg caaaaattag gtttgattcg ttctattggt
     6061 gtatctaact ttgaacctga acatttagat gccattattg aggcaactgg tgtcacacca
     6121 gccatcaatc aaatcgagat ccatccttac tgggtccaag aacaaatggt agcagaaaac
     6181 agaaaacgtg ggatcattac tgaagcatgg agtccattag gtcgcggcag cgcggcgctc
     6241 aaagaatcca tcatcactga tctagcaaat aaatatcaaa aatctgcggg tcaagtcatc
     6301 ttacgctggc acgtcgatcg cgggattcta ccactaccaa aatcccgaaa cctgagccat
     6361 cagcgagaaa acttagctat ttttgacttt gaattgactg aagaagaaat caatgcaatc
     6421 aatcgcttga acaaagaaga tggacgtatt gaaggtcaag atccgaatga atatgaagaa
     6481 tttgagtaaa gtgagacagc ataaagctcc tgagggattt cataggctca catcaattat
     6541 aggaattgga atggtcacaa aaaaagaact gcgagatgac ttgccccaat tgaattcctt
     6601 agatctacta gcagcaaggc tctactgaag tcttgctgct attttatgag aagtaaaaac
     6661 ttctgacacg atcagttttc atttggatta tgcttttctc acagttcttt ttctgagtta
     6721 aaacttctgt acaatcagcg ttacaactga taatgaatgg cttctttgta ttgttcaaac
     6781 aatgattggt tcaattcatc gccgccatcc atatttgcgg aataaaagat gggcggataa
     6841 tcgattcctg cttgtttcaa ttgttggcaa acttcgacga taatggtatt aaggatcgta
     6901 gcgccaatca ccgttgaagt aggccccact ttttgatcca tccccttaat ctgacaacct
     6961 gcatcaccaa tttctccatg attatcgatt acaagatcag cgacttcaaa cagacgaagg
     7021 cccgaagaat ggcggctagt gactgattgc gaatacgttt tgtttgttaa agcgataatt
     7081 ttgacgcctt tttcttttgc cgctagtgct aaatcgatta tgacaggatt acgacctgaa
     7141 actgagtgta aaatcagcac gtctccttct ttgaacggct ggatttccgc taatgcggtg
     7201 ccgtagcctt ctagtcgttc cattttgcta gtaaaagtga tgggactgcg atccaacatc
     7261 agttctcgtc caaagatcgc attgatcgtc atcatccctc ccgcgcgata gtacatttct
     7321 tctgccaaga tccccgcatg actagcccca aaaatataaa tcgaatgctt ttctagattt
     7381 gctgtagtca agagacgaat tgcctcatcg attgcatgct gttccttttt ttcaacggtt
     7441 tctagtaatg catgaatttt atcaacatat tgatacatat taaattcccc caaatagact
     7501 gccgagacca cgaccaatga ttccccaaag tgatatgtca ttgccaccaa agatcagaat
     7561 ccagttttga atcgttgtgc tgaatagaac ggcagataca ccaactaaca agaccatcac
     7621 aaatgatgcg gcaatggtac caatgactgc gccacgcaag ccgccttgtc cttctccaat
     7681 aactgctgcg ccgccacatt caaagaaact ggtgataact aatggtacga tcaagattcc
     7741 aaaaacattc gtcgtattga caatgatcac aaggatcgtt gaggtgatca tagctacgat
     7801 aaaaccaata atcacggcat tcggacgata attgaatagg atcggtacat caaaagctgg
     7861 tttggctcca gggacgactt tttcagcaat cccttggaaa gctggaataa tttggttgat
     7921 caataggcgg accccataaa gcatgatcaa gagtcctgcg ccaaagttca agcctgcttg
     7981 aacagcaaac atgaccagat tcccaccttc tgggacaaga actggtgcga taattcctac
     8041 aacaatattc atcaaaaaca tcaccaaggc acctgtaatg gaaatctcac ggaaaaagga
     8101 caggttttct ggcactttta aatcttctgt cgatttttct ttgtttccta ctcgttttgc
     8161 cacgaagccg gacaccatcg ataagatccc tgtaggatgt ccaatcaaga acgaatcatc
     8221 gccagtggca tcccaaacat atttccgcat gatccaaggc ataaatgacc aataacaagc
     8281 agataaaaca gctcctaaaa tcaataatgg aatccccgac attccacctt caaccccacc
     8341 agcaacgatc acaaatggga accaccataa catatgaccc gtcaagaaaa tcgtcttaac
     8401 tggtgtaaaa cgagcaatca ataagtgcaa gatcaatcca aaaaacatag ctaacccaac
     8461 agttcccccg tattctgctg tgaaggtcac atcagaaaga ccatcggcta cttgaacccc
     8521 caactgtgtc tgaaccgctg tgttgattgg tgcgatcgtt cccgtcagca tattgacccc
     8581 tgcggtcaat gctaccatcc caaaggctgc tgtcaacgag cctttcacca cttcggcaaa
     8641 aggttttcgt tgcacgatca acccgatcat tgcaatcagt ccgagcaata ctggcggatt
     8701 ctttaaaata tgatctgtga caaaactcat gattatccct ctctttcagc taaaaacttt
     8761 tccatttgca ttttgacttc agcgacatcc atatattttt tgatgggata gacaggtgct
     8821 ttgacggaag cttgcaaatc attcaataat tcgtggcttg taaaataaac atctgcagga
     8881 gttgcttttg cagtagacaa atccgtattc tcagcagtcg ccttcagccc cagctcctta
     8941 atcaccttat cgatcgtcat ctttaacacc attgaacttc caacaccaaa tccacacaca
     9001 gctaaaattt tcatcttctt ttcctcctat tggaataatt ggcaaatctg ttctttgtca
     9061 ccattcaaaa taagttgata cttttcctga tccataaaca cttccatgat ttcctgcaaa
     9121 ctttccaaat gactttgatt gtcttttgca gctaaaacaa ggaaaatacg gaccgacttg
     9181 ccagctaaat cgatttcgtt tttagtcact agcaaactca tcccttgatg aaagacacct
     9241 tcccccggac gagcatgcat caatgcaaag taatcagcca ataccatata cgggccattc
     9301 tcctcaacgc tatggatcat attagcgaca tattgttgat cgatggcttt ttcatttaat
     9361 agcggctgac tcgccaattg aactgcttct tgccaagtga ggatttgatt cgtggtctcg
     9421 atatgatcct caggcagtaa tttttttaaa ttgatcatga ttttacctcc aacatttttg
     9481 aaatgaacca ttctttgtct tcgatccctt gcatgatcaa cttcatgaca ggttctactt
     9541 cttgggcctc atcttctcgt atcattagta acacgatgat atcgactttt tggttgcccc
     9601 aatcaacagg acgatccaaa atcaatacag aaaaggtcgt ttttgaaaca aactcaggat
     9661 tgccatgagg tatggcaaaa ccgttatcta aataggtcga ctgcaatgct tctcgttcta
     9721 agacggaacg ctgaaagtcc gtacgctgat tttccgacga aaagtcattt tgactgatca
     9781 gaaaatccag tgcttgttct ttggtctcaa atcgttcaaa ataaatcttc ggtgcaatca
     9841 acatccgtgt atcttgcagg attttcacct tatccgcaat cggttcatta tcaataatca
     9901 aatcgatata gtgattcatg atccgcttca tgtctcgatt ggtcaccatc ggcgagatgc
     9961 ggacgactgg tttggaaaca tcaggtaaat cgatcgtgga aataatgaaa tcgatggcag
    10021 aaatatccat ctctttgagc ttagcgacag aagcggtttc aatactatcg acattaggca
    10081 atattcgacg aatcttggca gaaataaatg aactggtgcc aacaccgttc ggacaaacaa
    10141 agacgatttt attcaattgc cgcatccgtt ctactgcagc ttgaaagtga atcgaaacaa
    10201 acccgatttc atcctcagat attccaatat ggtaggcctt tagaaagtcg tccaaagaga
    10261 accaaacgac cccatacaac gccggataat gctgtttgat ctcatctagc aatggattga
    10321 ctacagtagt ttgggcctca atgcgtaaaa acagctggta caaatgaatc gtcaaatctt
    10381 cttctaagcg actatcctgt gtcaaatcga tctggatgcc ttcactgact ttctgaatca
    10441 gatttctgac tttccctcga aaagagaacg gaatcgattc gttcttcata aaaaaacgta
    10501 agccactacc tacaatgaga taggttaggt actgaacttc tttcgatgaa aaatggtaga
    10561 tttcttgttc ttcaatttct ttcaacaatt cataaatcaa cggatacttg tcaaattcca
    10621 aaaacaattt tccaaattgg cgcttctctt ctatatccag ctgatttgcc tgattcgagc
    10681 gctcgacaat cagcaagatc gaaacaacga tgctttggat gtagctttct gggatctcca
    10741 tttgcttttc ggtgatcgaa tggcgaaaag ccgcatttat cttttcaaat aatgacacat
    10801 ttgtcagaac agaaaggttc tccccatgct ccacagtaag gagaatgaat cgcttcaaca
    10861 ttcgttggat ttgtgactcg cttccttgaa aataagtgcc tgaattatca aaacgcaaca
    10921 gtaaattttc tttgacaaac agtgttttta gataagcgat atccttggcg atactgctcc
    10981 tagaaacata atactcatca gaaagttgct ggtaactcaa gtgctcccca ttgatcagcc
    11041 gcttaaaaat ttgcatgcgt cggtcttcga tcaaagaata attgtttttc atttgctcac
    11101 cctctacctt tattctagtg ataccttaac aaatatgaag accaattgtt agattaaaaa
    11161 atgattaaaa ggtgtgcaca ccctttccct tgatagcaat atcggtcgtt tgttccgcaa
    11221 aatcgcttca agcaagccaa acttttctca tcttcctcgt tttctcttat aataaatgta
    11281 aacagtcaaa tgaggaggaa acaaaatgaa atggcgtggg ggtagacaaa gttccaatgt
    11341 ggaagaccgc tctggtcgtt ccgcaggttc aggaggaaaa ataatggtcg gcggtggtat
    11401 cggtacgatt gttatcgcag tcctcttttt tctattcagt gggggtgatt taaactccgt
    11461 cacagatatt ttaggaggcg gacaagccgc taattatcaa acagaaaatg tggcttcaga
    11521 cgagtataca gaggaaaaag aattctccgc tgtcgtcttc ggccatttgg aagattattg
    11581 gaatggtgtt tttgaagcag aacagactac gtatcaagat cctaaactgg ttttatttac
    11641 aggaagtgtt caatcggctt gtgggaatgc aacttctcaa gttggtccct tttattgccc
    11701 tgccgatcaa aatgtttatc tggatctcag ctttgcaaca gaactttctc aaaagtatgg
    11761 ggccagcgga gattttgcca tggcctatgt cattgctcat gaagttggtc atcacgtaca
    11821 aaacgaactt ggtattacac agcaactcga taagatccgc caacaggttt ctgaaaaaga
    11881 atacaatcaa tatagtgttc gtttggaact acaagcggat tatttagccg gtacatttgc
    11941 caagtatcta caaggaaaaa cttataacgg ccaaccgatt ttagaagctg gtgatatcga
    12001 agaggctatc acagctgcta atgccattgg tgatgatacg ttacaaaagg aataccaagg
    12061 atatgtcgta ccagatagtt ttactcatgg gacttcaaaa caacgagttg aatggttcaa
    12121 ccgggggttc aaatatggtg atttggagca tggagacacc ttcaatgaaa aaaaccttga
    12181 tttggtctac ggatcataac aaaaacgttc ctttttagtc actctttttt cacatttggg
    12241 cggtatagtt tattcatacc aacaaaccct aactttttca ttttactcct tgcctgccag
    12301 tccccgctgg caggcccttt tttttcatgg tgctatttta gtttttttta acctttggcc
    12361 tgtttttttc tttaaaacgc taagggttga tcacaatttt ttcatatttt ccggttacta
    12421 tataaataac ccaacaaaca acccaacttt ttcattttta ctccttgtct gtcagtcccc
    12481 gctgacagac ttattttttt tcttgccaaa attctcaaaa tgcgctaagg ttatttatgc
    12541 gcggaagtgg cggaatggca gacgcgcacg cttcaggcgc gtgtgagtat atctcgtgtg
    12601 ggttcaactc ccatcttccg cattttgagc agatcatctt ggatgatctg ctctttttta
    12661 tgtgtttctt ttgtctaaat aaagaaaaaa gcttaagcta tataaattga gttaaattgt
    12721 attcgttttt cctcctatag gcgtatacta aagaaaacac ttgaggagtg gggaacatgg
    12781 aaacagaacg ccaaatccgt gaattggaaa aagcgatgaa tacgacagac aaccgccggt
    12841 tgtacgagcg tttcctggca gtcaagttgg ttcttgaagg ccacacccgg aaagaagccg
    12901 ggcacaccat cggccgcgac gagcatactg tcagccacta tgtgaaaaac tactgccata
    12961 atggaatcca aggtttagtc tccaaaaaac aaagcggacg accttcacgg ctgacagatg
    13021 aacaggaagc ggaactggtc caaatcgtcg cctaccacac tccggaggaa gtaggtttca
    13081 aatcccgtgc caattggaca ttggcgattg tgtgtgacct gattctccgg gaatggagtt
    13141 atggatatac gcaaaaaggc gtggcggacc tacataactt tccccctaga tattacgaat
    13201 atccaggggg tgttattgca tgcgtaacag cctatgctaa tttacaacat agatcgaagt
    13261 ggcttagctc taaaaaataa gccgcatctt tgtcagatac gactgtttag cattgctcat
    13321 tcaattagtt gatgattttt tcatcaaatt tcagatatag ttgaatattt cctttgttca
    13381 gcttatcaaa tgtcacttta tcaatgaatg ttcgatagat ttccttgttc tcactcttga
    13441 aacgattggc taacaacttt tcaacacttg ctcctttgtt tcgaaatgga ggctactcat
    13501 caaaaagaat aaattcacgg tactttctag agagtattga tagcaaaata tttaatccaa
    13561 tcattgaacg acttccttca attaaattgc ttggaagctc tcttgtctca taatataaca
    13621 aaaagtcgga atgctcgctg aggaaatttt ttcccagctc agtaactccg caaagtggaa
    13681 ttcggttcat attcaaattt ttgattgttg atttgatgct tggtgtctca ccgcttagag
    13741 acgtaacgat cacaaaatca tcttttgtca aagtatggct taacatttca aagtttgttt
    13801 cacctgaaat taacatggct ggtcgtcccg ataaaatcaa atcgtttaca aagtcttttg
    13861 aaaagttatt ttgcgtaaag cctgtcgcat agacaactac tgtttttgcc gcttttagct
    13921 gttctaatat cggttggaaa tttgtttggt ccgctaattg aaaagttcgg ttgatttcat
    13981 ctttcaatag tgcgataaga tctgtcggtg gaataaccga ttgaacgatg ctctgttcaa
    14041 gagaatattt catttcagaa tacccacgaa atcccaattt ttttgctaaa cgtaagacag
    14101 aacttttaga agacaataat tgttctccca attctacaat ggacatgtga actacttgag
    14161 ctttatgcgt acgaataaaa aaaaccatat ctttttcatt atctgagagc aaatcaaagt
    14221 ttagtcgaac attttgttca aaatccattt tctcacctct catatataca gaaggaattt
    14281 cggataaaac ttgcgctgtt ttatccgaaa ttctttctta ttgcccaaat tctaacacag
    14341 tttttacgtg cttgctatat atgataaaca agtgcttcgt aaggtcgtaa tataaactta
    14401 tcttccaatt cagatggtga ttgctcataa tttgatagaa gaagaacccc ttttcgacct
    14461 tgcaatgatt taggtaattc atagggaaca gactcttttg aaaaagaaca gatcaccact
    14521 aatagttcat ttttatactc acgtatataa ccaaacactg ctgaatcatt ctcattgatc
    14581 aatttatacg taccatgctg aatgattgga tagtttttac gcagtgaaat cagtttttga
    14641 taatgataaa aaactgaatt tggatttttt aaagcatctt ctacattgat ttgttgatta
    14701 tctggcgaaa aagagatcca aggatcactg ttcgagaatc catacccttt tgaatgatcc
    14761 caaggcattg gtgttcgtgc gttatcacga gatttcaaat aaatagcacg tttgatgtac
    14821 tcatcactct cgccttcttc tttcatcttt ttataaaaat agtttgtttc aatgtcttga
    14881 tactcatcaa ttgaagaaaa tggaacattt ttcattccaa tttcttcccc ttgaaaaata
    14941 aatggggttc ctttcatcat gtgaagtagt gttcctaaca tcttactaga ctctatccga
    15001 tattcgtttt catcaccaaa tctagtaaca gctcgcggtt gatcatggtt actccagtaa
    15061 agagaattcc aaccatctga aagcgcttct tgccactcac ttaacgtagc tcttaaatcg
    15121 ctaagcttaa accttacatc tgaaaacttt ccatactttc cataatcaag atgcatatga
    15181 tcaaaatgaa aaaccatatt taattcttta cgctcaggaa acgtataaag ctgtgcctgt
    15241 ctgctatttg tgttcggtgt ttcaccgaca gttaagctgt catatttact caaaacttct
    15301 cgattcatct cttgtaaaaa ttcatgcact cgcggaccgt tggatgctcc gacataataa
    15361 gactttgtat agggcatgct atttggagca tcaggataat caggatgctt gctaatcaag
    15421 ctgataacat ccattcggaa tccatcaatt ccaagatcaa accatttttt catcatttta
    15481 taaatagact gacgaacttt cgggttctcc cagtttaaat ctggttgttc ttttgcaaaa
    15541 caatgtaagt aatactgctt tctactctca acatactccc aagccgaccc gccaaatgtc
    15601 gatccccaat tcgtaggtgc actcccatct tctttgggat ctttccaaat ataataatca
    15661 gaatatggat tttctttatt tttttgtgat tctataaacc aagcgtgctg attacttgta
    15721 tgattgacga caaggtctaa aataactcga atattcagtt gatgcgcctg ttccaataat
    15781 ctcttaaaat cttctaacgt tccataattt tctgaaattt tctcatagtc tcgaatatca
    15841 tatccgttat caattagcgg agagtcaaaa attggagtta gccagataac atcaacccct
    15901 aactttgcta aataaggtaa tttttcaacg atccccataa gatctccgat gccatcattg
    15961 tttgaatcct tgaaactttg aggatacact tggtagacaa cactactttt ccaccattca
    16021 ttcatccgtt actcatcctc ctcatcaacg actatatttt ttaagtaatc attgacataa
    16081 accaattggt cttgtgcttc ttggattgcc tcacggatgt ggttgtctgt caatcttttg
    16141 tttaatgtat tcaataaaat tgtcaatacc acaggtagat tcatcccggt aatcagatag
    16201 acattaggtt gattgatata ttttataaat gcttgattga ctgaaccacc tagcatatca
    16261 gtaaaaatca atatatcagt atcctcattg tctcttacca ttacttcgtt aatcttttct
    16321 tctataggtg agttatcaat ataacctgcg attgcagtta tttcaccaac attcggtaaa
    16381 atatattgga cagtatcttt caatcctaca gctaaattat gatgactagc aaaaataatt
    16441 tttttcattc tttattctcc ttaaaccttt aaaataccga aaaatgatag aatcaatgcg
    16501 aatatgatca ctgaaaaaat aatttgaatg accgtcattt tttttgaagc tatcaattta
    16561 taaacaataa ttgttaaaac tgcaggtaag agtgctggca tgattttatc aagaatttct
    16621 gtttgaatag gtaattttac ttttccagat tgaaaaacca ctgcaacatt catttttaca
    16681 acagatggaa tcaaagctcc aacgactgtc aaacccataa ttgaagcaga ttctgtaaat
    16741 atcgataatt tacttcctaa agcagtcacc aactttaacc ctgaagtata cccaatcgaa
    16801 aaaagtttaa atcggaagaa caaaaagaat agattcaaac ataaccaaat aatggcacca
    16861 gtcggatttc cttctagacc catataagct gcaatcgagc ccataatcgt tggataaagg
    16921 acccaaacca acgtgtctcc cacaccagct aaaggaccca tcatcccagt cttaaaactt
    16981 tgaactgcat ctaatgaact gactccatct ttttcttcca ttgctaagct ggcacctaat
    17041 aataaattcg ccatccaagt cgttgtattg aaatatttaa aatggttatt cagagaagct
    17101 ctgtagtctt catcatttgg ataaattttt cttagtgctt tttcaagtcc ataaacaact
    17161 gccggacctt gttgattttc gtaattgaag atattacatg ccataaacat atagcgaaat
    17221 gctgctctac gtatatcttt ctttgataat ttatttcctt cattattcat caaaatcatc
    17281 tccttcatcg actatattgg cagctacagg tgatgccgtc tctgcttttt ttatttctgt
    17341 cgtgaaaaag taatacgcta aagcaaagcc gacgattgaa attcccaaaa taggcatgtt
    17401 taaataggcg gaaagtacaa aaccaatcaa gagcatcgtc atatattttt tcaccggcat
    17461 aacttgtaga agtaatgcta ttccgactac aggcaacatg cttccagcaa tcgataatcc
    17521 atctgtaaac cacttaggca caaaatctaa aatcaatcga acaattctat caccaaaaac
    17581 aacacacaat gcagttggaa tggctgtaga taatccgaaa atcactggtc ctaaccacaa
    17641 aatctgattc attttcttaa aatccatttt atttgctgcc ttttgtgccg catgagtaac
    17701 atatgtgttc aatattttag ccaacacatc taattgaatt cccagcatcc caacaggaac
    17761 acctactgct aatgcaacag cttttgcttc ttcaatatta tttgtggtac ggatggctac
    17821 gtagatacct acaagagcag ctaaacccca gttaggaacg gacgatcccc caatattcgc
    17881 tacacccaaa gccattaatt gaaacgtacc gccaataacc attgcggttg tcatatctcc
    17941 cataatcagc cctgcaaaca aagcaatcat gatgggaaac catgttgtaa tgaccaatcc
    18001 ttgttgatct aatacaaccc acactgctaa aataataatt aaaattcctt ggataatttc
    18061 cattccaatt atctccttta ttttattctc acatctaatg gttcttcagg atctgaagga
    18121 acaaaatgaa aagtaactgg tattcccata gcctctaatt tttttaaatc agcaatttct
    18181 tgttcatcaa ctgaaaccat tttttttact gtttgtttcc cttcaccatc aaacatgatc
    18241 ccgatattca cttttggtat atcgataccg ttctcagcta gttttactaa tgtactcggt
    18301 tcttttacga tcataagcac attatgactg tcatacttgc caagtttgaa attaataata
    18361 gctgtatctg tatcaataat tgacatcccc gttccagctg gcttactcat tcgcattgct
    18421 gctttttgtg tgtcatcctt actgacttga tcatctacga ccatcaatcg ttttgctttt
    18481 gtcgcacctg cccactgtgt taccacaata ccgtgaatca atcgttgatc gattcttgct
    18541 aatactaatc ccatatctat cgtctccttt tttgttatcg tttacatccc aaagtatatc
    18601 tacgccttgt tactttaaca atagttttag aagtatcagg gaaacagtcg ttatcttagg
    18661 aaatagtttc tttattaaga gaaatttccc acaaaaaaat agcccaacca tcgattagat
    18721 gactgagctc cctaaattta cgctatcttt tattactatt tacttctttt ttatcgcaat
    18781 ccaaatttcg ccatcacaat ccgtcaactc ttttgagaaa tcagtaaagg agagttctga
    18841 tgcttgaacc aactcatatt ctgaagttgg caaccactcc gcgtatattg acccgctgac
    18901 atccctaaaa aaggtgcgag gtggagaata tttttgatac aactatcctt atttatgata
    18961 tggagccccc gcattgatcc ggaaggcacg gtagatttgc tcgacaagga tcagacgcat
    19021 caattgatgt ggatacgtca tttttccaaa agagatgtga gcattgcttc ttttcatgac
    19081 ggcttcgctg agtcctaaag agccgccgat aacaaaaaca aggtggcttt ttccttggat
    19141 acctaattgg tcgatttgtt tagcaaaaga ttcgcttgtg ggatttttcc cttcaattgc
    19201 taaggcatag acgtattctt gttctttgat tttcgctaag atccgttccc cttctttttc
    19261 ttttacttgt ctcatttgcg cttcgcttaa attctccggg gctttttcgt caggaacttc
    19321 gatcaattcg atttttgcat aggcattcag ccgtttgaca tactcattga taccttggat
    19381 caggtatttt tcttttaatt ttcctactga gataattttg atattcatgt tttctctcct
    19441 ttggtcttca tgctcacttt gtttattata atcaattttt tcgtctatat gtttattttg
    19501 gctatttttg ttaaaaagat ttccccaaca gttatgcaca acatccacag gtttatccac
    19561 agaaaacagt gttattttac cttatttcat cacatttatt aggcaaacat acgttttata
    19621 agaatttatc cactttatac acaggctgtg gatatgtttt atcccttatt tttccaatcc
    19681 tatccgcgta gttttacaca gtttctgtgg aaaaaagcaa atcaaatatt ttcatctgaa
    19741 aacaatggtt tttcctaaag tttttcataa aaagttcaca gtctcaaagt agactaaagt
    19801 caacaaataa gagtatacta acagtagata aatgaatgta attggaggag gaacacatgg
    19861 atagaaaaaa tgtgacacca aagatgaaaa aaaataaaaa taatagcctc tggcgtaagt
    19921 taggtctagg gcttgttgga gggatcgttg gaggattact gacagctggt attttttatg
    19981 cagcgatggg cactggcaac aatagttcta ctacaagtgg caatcaaaat tctgctggtg
    20041 aaacagttgt ggaaaacgtc aaagtcaatg tagattctga tatcaccaaa gcagtagata
    20101 aagttcaaga cgctgtcgtt tctgttatca acttgcaaag tcaaaaccaa tcaagcggtt
    20161 ttggcggact attcgggcag caagaagaaa gtagcagctc agatgatagt aatttggaag
    20221 cttatagtga aggaagcggc gtgatctaca aaaaagacgg gaatactgct tatgtagtca
    20281 caaacaacca cgtagtagat ggccagcaag gtcttgaagt cttgatgaaa gacggtacga
    20341 aggtaaaagc tgaattagtt ggaacagatg cttattcaga tttagcggtg ttgaagatca
    20401 attcagacaa agtcgaaaca gttgcctctt ttggtgactc aagtgctctg aaggttggtg
    20461 agcctgcgat tgcgattggt tccccattag gatctgaata tgcgaattct gtcacttcag
    20521 gaatcatttc ttccttgaac cgacaagtaa caagtacaaa tgaatcgaac gaaacagtca
    20581 atatcaatgc gatccaaaca gatgcagcaa tcaaccctgg aaattctggt ggtcctttag
    20641 tgaatatcga aggacaagtt atcggtatca actcaagtaa gatcgcaagt acttctgaat
    20701 ctacttctaa tgtaagcgta gaaggaatgg gatttgctat tccaagtaac gatgtagtga
    20761 atatcatcaa tcaactggaa aaagacggaa aagtgacacg tccagctcta ggtatcacaa
    20821 tggtcgactt atctgccgtt tctactcagc aacaagaaca aatcttgaag attccttcat
    20881 ctgtaactaa cggtgtcatc gtgacaaatg tccaaacagc tacaccggct gaaaaagctg
    20941 gattgaaaaa atacgacgtc attactaaga tcgatgacaa agaagtttct tctggtgtag
    21001 aacttcaatc tgctttgtat aagaaaaaag tgggagattc tgtcaaaatc acttactatg
    21061 aaggctcgaa agaaaaaaca actactgttg aattgacgat cgatcaatcg gcattaaaac
    21121 aaaatcaaaa tagtgaaaat taataaaaaa gaggttaggt tgtggcaaag acttgtcaca
    21181 acctaacctc ttttttataa actatatttt tcttgccaac tcctcggtca caagtcacaa
    21241 gatccaacaa acatgagaag ctgttttttg aaattgctcc ttgtgactca gagtgaaacg
    21301 gcagactcac aacctcttta ttttggaaat gcttctccga ctacggcatc ctcaggcaat
    21361 actaagattc ctttttttgc tggagcattt ggcaaatgca attcacgagc ggaacagatc
    21421 attccatagc tatctacccc tcgcaaagtt cctggccaga tcatcattcc atctggcatc
    21481 atagctcctg gttttgcaac gacaactttt tgtccagctt cgatattggg tgcaccgcaa
    21541 acgatttgca atactgtacc attgtctact tctgtctcag taatcgataa atggtcagaa
    21601 tcaggatgtg ggacgcatgt ttttacgtac ccgacaacga tcttcggttc atgatcagct
    21661 tcaagctgtt cttcgaatcc tgcttctttg atcaatcgat tcaatttcgc taattcctca
    21721 tctgttaagc ttacttggcc gttcccttcg attgttagat gatcggagat atggaaaaag
    21781 ttccaagcaa caacttgacc ttgttcatct ttgatccgag caacattcca tttgcgttca
    21841 acagtgtttt ctgttccttt atcgtcggct ataataacca tcaaggtgtc tccgacgtgt
    21901 gctttgttat aagcaaaaat catgttcttt cctccattat cctttgctga gatttatctt
    21961 aacaaaaaat tgcattcact gcatgagatt tttttcatgc tttatttccg aagaagcctc
    22021 ttctggaaca ccatttattc gtaacaaggg actgtgacaa gacttttgtc acagtccctt
    22081 tactgtttta gttaattgat taaaaaggtc gtacaagttc cacttgctta attacttggc
    22141 tgttcttctt cgtcagaaac gatcaagaca tcacaaggtg aatgacgtat cacgtagctg
    22201 gctacacttc ctgtcataaa gcgttcgact gcatttagac ctgactgccc aaccatgatt
    22261 agatcgatct catatttttt tggcaatttg actgccatgg attcacgaac agaaccatat
    22321 gcaataattc cttctatatt tgtgtaatca acagatttcc catattcttt acattcttcg
    22381 atcatttcct tggctgtttc agtttgctga tcgactagat tttgatcaat aggtgcatag
    22441 cccataaagt tataaaattg ctgatcgatt acgtttgcta catatacttt cccattatta
    22501 cggcgagcca cttccaccgc ttttttgaaa gcagcaagtg cttgttcact accgtcgata
    22561 cctactaaaa tgttcttata ttcttgattc atcttgaccc ctcctaacag atgtcagcct
    22621 tttgtcacac tttctaggaa cgattcgatt tcctgttttg ttttacgatc tttattcact
    22681 agacgaccta attcttttcc gtcttggatc acgacaaaac ttgggatacc aaaaatgttc
    22741 cattcagcgg ctacatctat gtacttgtca cggtctactt caataaattg ccaatcagaa
    22801 aagtcatttt caatttcagg catttgcggt ttgataaaac ggcagtctcc gcaccagccg
    22861 gcagtaaaga aaaatacact ctttccagtt tctacgtagc ctgctaattc ttctaaacta
    22921 tttgggataa tcattctttg tcctctactt tctgtttatg tatttttcaa ttaaattata
    22981 cacctttctt tcgaactaac aaacattgat cctcttttta taaaaaaaat ctggcaaaag
    23041 caatcttttg ccagatttta tagtttcact atcgcattat tttccgtata cgatcgtatt
    23101 cactgttgat ttatccaaac ctttcagtgt ttgtatcaac atttctcgtg cagcttcaaa
    23161 atcgcgaata ctgaacatcg tttgatgcgt atggatataa cgtcccacta cgccaatcac
    23221 tgtacttggg attccttcgt tttgtgtatg agcagcacct gcatctgtac cgccttttga
    23281 aacaaagtat tgataaggga tattgtttgt ttcagcgata tccagcaagt actcgcgcaa
    23341 acgaggaagc atgatcaaac ctggatcttg gatacgcatc aatgtacctt ctcctaaatg
    23401 tccgaatgtg ccatttttcg tcactgtatc atctgctgca gagcagtcta ctgcaaagaa
    23461 cagatctggc ttgaatttat tgacagaagc tttagaacca cgcaagccta cttcttcctg
    23521 gacattcgcg cctgcgatca atgtatgccc taatgtttca ttttgcaacg cttctaaagc
    23581 ttctaatacc attgtacagc catagcggtt gtcccatgat ttgctgatga tattctttcc
    23641 gttggctgtt ttgatcgttt cagcgtaagg aacgattgtg tctcctggaa ggacaccgta
    23701 actcattgcc tcttctcttg attcaaaccc agcatcgaac aaaatatcgg ttacttctac
    23761 tgatttttgt ccgcttgttc ctcgcaataa atgcggggga acggaagaag aaatacatgg
    23821 ataattctta ccagtagagg ttttaagtgt aaaacgctgt gcagaaacaa cgtaaggatt
    23881 ccagccgcct agaggtacga ctttaaaaag cccgttttct tggatttgtg tcagcatgaa
    23941 tccgacttca tccatatgtg ctgcgaccat tacacggggt gcatccgctt cttcatgatg
    24001 gcgcagacca aaaatgccgc ccaaaccatc taactgtaac tcatctacca gcggttccat
    24061 atgactttcc atataagcgc gaacatcttg ttcaaaaccg cttgttcctt gtaattctgt
    24121 taactctttg attcgttgaa atgttttttc ttccatatgc tattcgtcta aatttcagac
    24181 taaactcctc tcagacttat attgatctgc ggataaaata tgattttttc tgcagaccga
    24241 tcgtatttat tatagcttat tttttctggt agcggttatt tatttcaaag aaaatatgag
    24301 agtgtggtaa aataagcaca aggagtaaca agtgagaaga aggaggtatg tccacatgta
    24361 tgaagaaagc gaactaagct attttaaagg cgggttagca gttggaatcg gtctaggatt
    24421 attgagcggg gtagcttcaa cgatttggta tcatcgcaaa aaagtattgt cagcagacca
    24481 agtacttgaa aatatcaagt catcttttct aaaagaaggt gcaatcgaag gttcttggat
    24541 ctcttttgaa aaggaaccta ttaggaaatt cgccgttcgg tcgagtgctt atcggggagg
    24601 tctttctcga atagaagatg gcgaaactgt ttattatgaa tttttagcag atgctcatac
    24661 aggaaccgta ttagaaattt caagaaaaaa aggtgcaaca gattaatacg tcaaaaaagt
    24721 gagagaacga atacgcaccc actattcaaa agagaggtat cctatacttc ttttatagtg
    24781 ggtaattttt ataaaaatag ggctatttcc tcttggaata gctagtatta tagttattat
    24841 at
//
LOCUS       DAXLPC010000035        24272 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.035, whole genome shotgun sequence.
ACCESSION   DAXLPC010000035 DAXLPC010000000
VERSION     DAXLPC010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.035"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..572
                     /locus_tag="ACF3UE_001381"
     CDS             <1..572
                     /locus_tag="ACF3UE_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFD3634801.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="ACF3UE_001382"
     CDS             576..1217
                     /locus_tag="ACF3UE_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3634802.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDFIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="ACF3UE_001383"
     CDS             1214..2131
                     /locus_tag="ACF3UE_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3634803.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="ACF3UE_001384"
     CDS             2128..2799
                     /locus_tag="ACF3UE_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3634804.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="ACF3UE_001385"
     CDS             complement(3340..3828)
                     /locus_tag="ACF3UE_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFD3634805.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="ACF3UE_001386"
     CDS             complement(4029..4295)
                     /locus_tag="ACF3UE_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFD3634806.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="ACF3UE_001387"
     CDS             complement(4295..4558)
                     /locus_tag="ACF3UE_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFD3634807.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5079..5219
                     /locus_tag="ACF3UE_001388"
                     /pseudo
     CDS             5079..5219
                     /locus_tag="ACF3UE_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(5361..7184)
                     /locus_tag="ACF3UE_001389"
     CDS             complement(5361..7184)
                     /locus_tag="ACF3UE_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD3634808.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..10487)
                     /locus_tag="ACF3UE_001390"
     CDS             complement(7782..10487)
                     /locus_tag="ACF3UE_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFD3634809.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10793..11740)
                     /locus_tag="ACF3UE_001391"
     CDS             complement(10793..11740)
                     /locus_tag="ACF3UE_001391"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFD3634810.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11930..12199
                     /gene="rpsN"
                     /locus_tag="ACF3UE_001392"
     CDS             11930..12199
                     /gene="rpsN"
                     /locus_tag="ACF3UE_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFD3634811.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12375..12737)
                     /locus_tag="ACF3UE_001393"
     CDS             complement(12375..12737)
                     /locus_tag="ACF3UE_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFD3634812.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12748..13869)
                     /gene="alr"
                     /locus_tag="ACF3UE_001394"
     CDS             complement(12748..13869)
                     /gene="alr"
                     /locus_tag="ACF3UE_001394"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFD3634813.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13885..14235)
                     /gene="acpS"
                     /locus_tag="ACF3UE_001395"
     CDS             complement(13885..14235)
                     /gene="acpS"
                     /locus_tag="ACF3UE_001395"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFD3634814.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14365..15876)
                     /locus_tag="ACF3UE_001396"
     CDS             complement(14365..15876)
                     /locus_tag="ACF3UE_001396"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFD3634815.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16198..17550)
                     /gene="murF"
                     /locus_tag="ACF3UE_001397"
     CDS             complement(16198..17550)
                     /gene="murF"
                     /locus_tag="ACF3UE_001397"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFD3634816.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17703..18779)
                     /locus_tag="ACF3UE_001398"
     CDS             complement(17703..18779)
                     /locus_tag="ACF3UE_001398"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFD3634817.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18975..20720
                     /locus_tag="ACF3UE_001399"
     CDS             18975..20720
                     /locus_tag="ACF3UE_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFD3634818.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21000..21437)
                     /locus_tag="ACF3UE_001400"
     CDS             complement(21000..21437)
                     /locus_tag="ACF3UE_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFD3634819.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21421..22794)
                     /locus_tag="ACF3UE_001401"
     CDS             complement(21421..22794)
                     /locus_tag="ACF3UE_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634820.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23116..23604)
                     /locus_tag="ACF3UE_001402"
     CDS             complement(23116..23604)
                     /locus_tag="ACF3UE_001402"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3634821.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23626..24228)
                     /locus_tag="ACF3UE_001403"
     CDS             complement(23626..24228)
                     /locus_tag="ACF3UE_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFD3634822.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6960 a         5166 c         4485 g         7661 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgattttatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agcccaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaaa tattccctaa tgtaacgatc
     8221 aagctttgcg caatcgccat tgtcaaaaat gtcagcatac gagcaacgaa ttgttctcgt
     8281 ttcgtaaaat tgtttcggtc tttctttcct aaatagtatt ctgtcgtagc aacacttgaa
     8341 agaagaacag cgccgaccca cagacatagt gcagtataaa acggggtgct agctgaaccg
     8401 ttatttgcga ttggataaag cgcattggtt tgtagctcaa caggttgtgt aaagaagtca
     8461 ctttcttttg ttgcgtctag tttcaataat ttgatgactt cgcctagatc gacttcttgt
     8521 tcgccttttc ggatcgcgtc tgctgctttt tggataccag ctttgatatt tggccagtca
     8581 ttgttgatca agtccgcagc agcgttcaca gctgtttcga cttctggcat tttttcattt
     8641 actgttgtca atgtaccggt gatttcattt tttagtgctg gccaatcatt ttggataaaa
     8701 tcagcggcca atcctaattt ttgctgaatg atcggtaatt cattgttgta taggtctgcc
     8761 ccttcattga tgccattgac gatggtatcc atatttccat tcagcattgt attggcatca
     8821 tggatttctt gtccaattgc aggcatttct ttttgatatt tttctaaaat tgccactgca
     8881 ttcgttacag ttgctttcgt tgagctgaga agcgaatcaa agtcgatctg gtccgctttg
     8941 ctcagtgcgc cttgtgcagt cccaatcgta tcgatgactt ggtctagtag agaagtgaca
     9001 gtggaactga tttgacctgt attgatacca gcaatgatgc cattgatatt attaacaacg
     9061 gcatcaattt gatctagcaa ttcatcaata gccttcgtgt cttcattttg aacagctgtg
     9121 ttcaaagcag ataggcggtt ttgcagattg cttagcaagg gttttaattg atttagctga
     9181 tcaataattg gctgtaattt cgtatttcca gcacttgttt gcaatttagt caggaactcg
     9241 accagtttat cgattgcatt ttgttgttga gatattccgt caataaagcc gttcaataca
     9301 ttgctgatgt ttttcttttc atcatcagtc agcttaccat cttcaatagc tgttcttaca
     9361 gtatctatta acgaacctgt cgttgttgcc acttgtccaa ttgacttcaa tgtaacatct
     9421 acactgtttg tgatgcttgg tatcgcatct ttcagctgag aggcacctga ttttgtttgg
     9481 tttgctagat cacttgcctg attttctaaa tttttcacat ctggcaagat atcttgtact
     9541 tgttggatga tcgtcaagcc ttgttttgct tcatcgattc cttggttcat tgtctcttgg
     9601 atcgaagcaa aatcgccgtc gatctctgct agttgcttac cggcattttg gatctctggg
     9661 attttttctt gcaaatcaag gatgattttt gcttgatctt tcaactcagg cattttgtca
     9721 ttcaatgcaa cgactttttc acccatctca tctactttag ggatgtaatc cacgaattca
     9781 tttgctttat tcagtttttc cttgatttca ggtagttgac tttgtaattc gaggacttgt
     9841 tttgtgtagc cgtcgatcgt gtccaaattt tcatctgttg ataaaatcat atctttaact
     9901 ttattgatac ttactaggtt cgtatcgatg tcgtaaccta tctcattgaa tactttcaat
     9961 aaagtcgaac tggctgtttt gataaattca tttgtgattt gcgattggat cgaacttgct
    10021 cctttatcgg tgattttcgg tgcaatcgca ttgatttttt catttaccgt atattcgatt
    10081 tttggtttct tgatatcacc actagtaaaa ctcagcagat cttctgagaa atcctttggc
    10141 aagtaaatac ctgcgtaata ctttccggaa cggactccgt cttctaattg ttcttttgaa
    10201 tcaacgaatt gccatcctaa ttgtttattt ttatgaagcg attcgatgac ttgctcccca
    10261 atggccactt ctttaccttg aaactctgct ggcttgtctg cactgtaaac agcaattggc
    10321 agctctccag tatttccata tggatcccat aatgctttga tgttaaacca cgcatatagc
    10381 gaagggatga tcatgatcgc gatgatcaga agtgttgcaa tcgggttttt gaaaatccgt
    10441 ttccagtcaa gcaaatataa tcgaagcgta tttttgattg actgcatagt tctccccctt
    10501 cttctttttt cagctgaatt actttaccat gtatttcata cttttttcaa tcggcttttt
    10561 tcaaaaaagt cgaatttttg gacatatcac ggcaattgtc tcattgtaat ctcttacata
    10621 ttgagaaata attaaggatt acagccttta ctttatcatg aaataaaagg gaaagataat
    10681 tttatgccaa agtttttatc tattatacgt atacgcaaaa aagctaaaac attttttgtc
    10741 tttgccccta caaaaatgtt tcagcttttt tcgtttttta ttcctgtatt tcttattttt
    10801 cgaatgacag gatgattttc ccagcaggag gatgtccttc aactagctga tgtgcttgga
    10861 tgacatgctt aagtgaagca gacagattca ttgaaataaa aacatgaaag gctccttttt
    10921 ggtaggcttt gattatgcca gcaaaggctt ctgcatctag atattccttt cttggaacaa
    10981 acgattcata aaagccttcc tttttttgcc gcaaatctag atctgggagg tcatttaatg
    11041 caacatacct gccgcctggt ttcatgatct ggatgccggt ttctcctttg atacttcctt
    11101 tcgtcgcatc gattacaagg tctgcctgat cagcaaattg cagacctgga tttgttttat
    11161 cataagcagc aaatgctgaa gctcctaatt tttttacctt ttcctcattt ttactggatg
    11221 cactggttaa gattcggatt cccttttcat ggagaagctg gatcagactt gacccgaccg
    11281 cacctgatgc tcctagtatc attacagtat ctgtcggctg gatttccgtc aaatggttga
    11341 ttagattata agccgtaatt cctggcgtga ccattccggc tgcttcttcc caactcattt
    11401 tatctggaat ttttgctact tttgctgatg gcaacacgac ttcttctccg taagtcccgc
    11461 cgactgcatg gacagctact cgatcaccta catgaacagt tgtgacatct gaaccaatct
    11521 ctgtcacaat accagcgcca tcattacctg gtacataagg gaatttcaat gttcgtatct
    11581 ctttcatttc tcctaaacgc aaggcaacat cataaggatt cacactgaat gcttttattt
    11641 ctacacgaac atgtccagaa ccgacttctc tgggatgagc atcgatttct tcaaaaacat
    11701 cttgtgcttc tccgtaaccg ttaattgcaa atcttcgcat ggtcaccatc tccctttttc
    11761 tttaagttta cgtttatgcc tttattttga caaaaaaaat gtcttttcgt tttggcgcat
    11821 gattcaaaac aaaatagttg tcttttttcg cgtaacgtgt taaattattt atctaaaagc
    11881 gtaaagatta cgatttacgc taataaaaaa taattggagg aatttgttga tggctaaaaa
    11941 atcaaagatt gccaaagcaa aaaaacagca agaaacgatt gaacgctatg ctgctttacg
    12001 ccaggaatta aaagcgcaaa aagattacga aggcttgcgt aaacttcctt tagatgctcg
    12061 tccagaacga ttgaaaaatc gtgatttaat cgatggacgc cctcgcggat acatgcgtaa
    12121 attcgggatg tcccgtataa aattccgtga attagcacat aaaggtttga ttccaggagt
    12181 aaaaaaagcc agctggtaat ccaagtctgg ctgtaatgta aaggaggagg gcgcatggac
    12241 cactccttgg atcatcaaaa aagatacgtt cgcttcttct agcagaaatg ctggtactag
    12301 aagcagacgt atcttttttt acgcacagct ggtccttttt tatatgtaaa ggctgcatgg
    12361 ttacttcgct atatttattt agtaacagga gtcagtgctt cgatacccac actaattttc
    12421 aatgctcggt caacttctgc cataatgggt cgatccaaat ggcagacctt ttctttcaat
    12481 cttgatttat cgatcgttct gatctgctcc aacaggataa cggagtctct ttctattcct
    12541 gttccagtag ctttgatccc aatgtgagtc ggaagcttag gtttagccat ttttgccgtt
    12601 atggccgcaa caatgatcgt cgggctaaaa tggttaccta gattattttg aataaccaaa
    12661 actgggcgtg ttccgccttg ctccgatccc acgactggag aaagatcagc aaaataaata
    12721 tctcctcttt ttaccatagg atcctcctta ttcttgatat tctcttggta tccgctgtcc
    12781 taatccgcaa gccacttcat agtggatcgt acctaattga tctgctatat cctgcatagt
    12841 gatttctttg tctgcatttt tgccgataag cgtcactttt gttccgacag gaaattcttg
    12901 aggcaatcgg atcatcagtt gatccataca tacacgccca atcgtttcac agtagttccc
    12961 ttctaccaat agagaaaaac cctgcatctt tcgtggccag ccatctgcat aaccgatcgg
    13021 tatcgttccg atccactctg cttcaggagt gatatatgtt tctccatagc cgattccttc
    13081 acctgctggg agttttttga cttgaatcaa ttcagaaacc agctcaagtg ctggctgcaa
    13141 tggataaact tccggtagtg cgtgcccaga gggattaagt ccgtacattg ctactccata
    13201 acgaatcata ttgccgattg tttcatcatg ccataaagcc gttgcactat tgctgacatg
    13261 tacatatcga ggaagttcgg gaagtttttt cagcacttct ataaagcgtt ctttttgcag
    13321 attccaatat gtatcatctg cctgatctgc tgtagaaaaa tgggtaaata aaccttccca
    13381 ttctaataca cgactttctt tgatgaatgc agctgcctct tttacttctt caggtgtaca
    13441 aaatccgata cgacccatcc cagtgtctgc ttttagatga atcgaaagag gcgtctctag
    13501 cttacttttc tctaaaacag cagctgctgc ttgcaaccat tcccgtgtac ctgcagttac
    13561 tgataaatca tgagcaacag ctacagtcag tgcgtcgtaa ggaaccatat tcaagataag
    13621 gatgggctga gtaaatccag cttctctcaa ctcgactcct tcatctaaat ttgaaacaca
    13681 aaagcccgaa gctccacctg caactgctgc ctcagctgtt tcaatagctc catgaccgta
    13741 tccgttcgct tttactactg caaacaattc ttttccttgc ggaagtcttg caacttcatt
    13801 tgctacattt tcagttatag cttttttatg tatcactgct ttcgttgggc ggtgccaagc
    13861 gacaaccatc gtttttcctt ctttctagtc ttccaaaata atttgtgcaa aagctgtttc
    13921 atttgtatga gtaatactga cccatacatt gccttcatga ggtgaacgcg tcacaacagg
    13981 ctgaccattt tcatttttta aaatctcgac atcttgaaag gtaacttttc cgatcccagt
    14041 tccccaagct ttagagaaag cctctttgca agcgtaacgc ccgcctaaaa attctacttg
    14101 gcgatgaaaa ggcaaggact ggaatagttt catttcatca gaggtcaaga ttcgtgcaat
    14161 gaattttggt ttttcttcga tcagccgagt gatcctagga agttcgactg catcgatccc
    14221 aattcctttt atcatatgct tttctctttt caataaattt agaacactct cattctacca
    14281 aattataacc attttgccac aaataagtcc acaaataaca aaaatgaaag tttctcttaa
    14341 aaaagagaaa ctttcatttt atgtttaatc gttatttgaa cggattacaa atccgcgttt
    14401 tttatcattg tgacgtttac cgccatcttt ttggctgtta ttatttttgc tataaccgcc
    14461 ttttgatttg tttccacgat aattaccgcc gtcacgacga ttacggttgt ttccgccacc
    14521 acgtttgcca tttttattgt atcctttttt ctgcattggc aatgggcgtt ctggtgtgat
    14581 cttcactggc actgcatcag ctggatcttt tgctgtcgtt tttagcaaaa gtgcaactaa
    14641 atcttgtgca gaatattctt ctaataattt atctgctgtt tgcaggtatt tatctagacc
    14701 attttctgca agttttgttt cgatttgttc aactgcagca cctaattgac ctttgaatgc
    14761 ttctttttcg gttggtggac gtaaagtcgt catccgtttt ttcgtcaagt tttcaatcac
    14821 atgcaagtag tccatttcat ttggtgtaac gaaagtcaca gacataccgc cttttccggc
    14881 acggcctgta cgtccgatac ggtgaacgta gctttctgga tcttgaggga tatcatagtt
    14941 gtacacatga gtgacacctg aaatatctaa tccacgtgca gcaacgtctg tcgctacaag
    15001 gatatctaaa tgaccgctct taaatgaacg caatacgctc attcgttttt gttgagacaa
    15061 atcgccatgg attccttctg cacggtaacc gcgtgcttct aatccgcgtg ccaattcgtc
    15121 tacacggcgt tttgtacgtc cgaagacgat tgttaattca ggtgtttgaa catcaaacaa
    15181 gcgagtcatg atatcgaatt tttcgtattc ttttgcgcgg acatagtatt gatcgatcaa
    15241 gtcagctgtc atttctttcg ctttgatctt cacatgatgt ggatttttca tgaatttaac
    15301 gccaatattc ttgatagctg gcggcatcgt tgctgagaaa agtaatgttt gtctttgatc
    15361 aggaacttgt gaaatgattt tttcgatatc ttccaagaag cccatattca acatttcatc
    15421 tgcttcatcc aaaactaatg tttgaacggt tccaagtttc aatgtgtggc ggttaatgtg
    15481 gtcaagcata cgtcctggtg tacccacaac gatatgtgga cgatctttca agccacggat
    15541 ctgacggcca atatctgctc cgccgtaaac ggcttgtaca cgtacttttt tgtcgcgccc
    15601 taaacgatat aattcttctt gtgtttggat agctaattca cgtgttggtg cgataactaa
    15661 accttgtaat tcgtgacgat ctggatcgat tttttctaac attggtaatc caaatgcagc
    15721 tgttttccct gtacctgtct gtgcttgtcc aataacgtct tttccagcta atgctagtgg
    15781 aatcgtttct gcttggatag gcgttgcttc ttcaaaacca gcgcgttcga ctgatttcaa
    15841 caattctggt gataattcta gttctttaaa tttcaaatga atcctcctat atggttgtta
    15901 actgaggatg tagctttttt gctaccccgt cgatttgttc ggtcaaagtg tattgtttct
    15961 ttttgacagt ggccacgcac gtttttatcc attcttagcc cctgtggcac caccgaaaaa
    16021 tcactttgcg aagtttaggc attagaaaag ccaaacgggt cgcgttcagc tttatcatta
    16081 ttatgacatc tggcttcaac aagttgtttc tatggcaaaa ccagtccaat ttctcttcat
    16141 ctttcggcaa taggttattc taacatagtt tttcgttttc tgcaagttta cagattttta
    16201 tttcatttgc tgaagttgtt ctaccacttc aaataagccc atgctgttgc tgccttttag
    16261 cataatacta tctgttgctt caagattttg tttgatagca tcaatcaatt tattcttttc
    16321 tttttcaaaa tagaacacag gtagttgggg gtatttttgg ttcaattctt cttttagtgc
    16381 atgcatttgt tccccataaa ggaaaatcat ggcgaatttc tcaggatcga tatgttcact
    16441 catttgcgca tgcatattta aagactcttt ccctaattcc agcatatctg ctaacacagc
    16501 gattctgcgt ccttttgttg gcagattttt aaaagtatct aataccagtc ccatggctgt
    16561 tggatttgca ttgtagacat cgctcaaaat agctgcacca tttcctgccg ttagccattc
    16621 ggttctgttt tgagtgatag aaacatgggc gagcccttgg cgtatctcag gtatggacag
    16681 tccaaagaag cgcccgatcg tatacgcaat caaagcattc gttacattat aacttccagg
    16741 cagcgggatc gtaaatgttt ctccttctac tacaaaatcg gtttgtgctt ttccttttgc
    16801 tgtcacttcc gcatgaacat cgccatttcc aataccgaat gttgtgactg tttgtactaa
    16861 tgttgccgtt aaaggtgtca gcaacggttc atctgcgggc acaacgagta atccgtctga
    16921 tacaagtccg tcagtgattt ccattttggc tttagcgatt ccttctcgcg acccaagatt
    16981 ttctatgtgt gcttcaccga tcattgtgat tgctgcagct tttggttgag ccataagtga
    17041 aagttccgtg atttcattgg cgtgatccat gcccatttcc aaaacgatct tttctgtatc
    17101 ttggggcatg tgcaaaatcg tgtaaggaag accaatatta ttgttgtaat ttccttgcgt
    17161 cttatatgtt ttgtattttt cagacaagac agacgcggtt agatctttcg tggtggtttt
    17221 accattgctt cctgtaattg caacgacttc tgcgcctact ttttccaagt aataggttgc
    17281 caattgctgc atggctttca aaggatctgc tacaggaata actggaaaat tttttggagc
    17341 ttgttcaaca ggcaagctcc aaaatgaagc agatgctccg tttgtgatcg cttgctggat
    17401 aaattcatgt ccatctcgcg taccagcaag aggaacgaat aaacttcctt cggttatctt
    17461 ccggctgtca aattcgacat tggtaatctt tgtcagtgca gagcattcgc tgcccacggc
    17521 ttgtgcaatt tcttgtattg ttagattcat tgagatctct cctaaaaaag gttgtgaaaa
    17581 aagcgtttgg cctaaacggc gggttcgcat gactctcact tccaagtaaa tttctctatt
    17641 cgtatttaga agctagaatg aacgcggtta cgcaatcact ccagcctctt ctttatttct
    17701 ctttattcat ttttttcaaa aaaagattga cgctgatggt atcgattcat tcctaactgg
    17761 atcagttctt caatcaaatc accgtatttc aagcccatat tttcccataa gagtgggtac
    17821 atactgaact ccgtaaatcc tggcatagag tttaattcat tcaggaataa ttcattttta
    17881 tttgtcaaaa agaaatcgca ccggctcaat ccgcttccac ctaacatcgt gtaagctaac
    17941 ttcgcgtact cttgcgcttt ttgataaact tcttctggca cttcggctgg aatctgcatt
    18001 tcgattttat tattgatata ttttgcttca taatcataga atgctacgtc ttttacgact
    18061 tcaccaggca aagtcgtccg aacgtcttca tttcctaata cagcaacttc gatttcgcgc
    18121 gcttcaattc cttgttcaac gattgctcga gaatcatact gataggctgt tgctaaagca
    18181 ttttgcagct cttctcggtt ttctgctttt gtaatgccga cactagaacc catattcgcc
    18241 ggtttgacaa acatcggata aagcaaagaa ccttcacatt gatcaaatac ttttttagga
    18301 ttttctttcc attgattctt aagtactggt acataaggaa cttgcggcac accagcagct
    18361 tgtaaaatat acttggtcat gattttatcc atggcacatg cactggtcaa tacgcctgcg
    18421 ccgacataag gcatattcaa tgtctctaag aagccttgga tcgttccatc ttccccgttt
    18481 ggcccatgta aaactggaaa aacgatggct ccttcttctt tgatttcgcc cggattgatc
    18541 acttttcctg taaagccttc ctctgtctgt ccacttgggt cccatgaaag atgcaagaca
    18601 tctttgctgg caggtttttc tgttagtaat ggacctttga cccattgtcc ttcttttgta
    18661 ataaatacga gttgaacttg gtaataatta taataaatgg catttaaaac tgaaaatgcg
    18721 gaaagaatgg acacttcatg ctctgcgctg cgtccgccat atagtaaagt aatcttcaaa
    18781 agattgtcct cctgtattct aaatcgttca gtgatttact ctcatatttt agcacaaaac
    18841 aaaaataaac gaataactta tttataaaaa aacgagccag cttctaaaag aacgagcgtc
    18901 atttattttt tgtcagctag attatttgtc ccgtttttta taaaaagtta tgataaagaa
    18961 aaggagggat gatgatggcg caaacaaatc cacgcagccg cttggcagaa atcattcgag
    19021 tgttcatcaa ttacaatgta gtgccaaact ttgtacagca aaaaaatccc gaacaggtaa
    19081 aaaaagcctt tgaagaacta ggccccacct tcatcaagat aggacagatg ctttctgttc
    19141 gagaagattt gctttcttct gccttcactc aaacattcaa aacattacaa gatagtgtac
    19201 ctagcgacac attttcaacg gtcaaaaaga cgatcgaaac agaactttct ctttcattat
    19261 cagatatatt cgatgatttt tcaaaatcgc cttttgcctc tgcttctatg gggcaggctc
    19321 atcgtgccaa gctgaagaac ggtgacgcgg tagtcgttaa gatccaacac cctaacatcg
    19381 ccgaagagat ccgacttgat cttcaactat ttgaacgagc gatccctttg atcaaataca
    19441 ttcctgaaac tagcgtagtt gatctaaaag gggtactcca agaagtaaaa cgttccttga
    19501 tcaatgaaat ggacttctta aaagaaagtc aaaatggcga acaattctat caaaagaaca
    19561 atggctggaa agagatccgc agccccaaga tttatgacgc tttttgttcg aaaaaagtga
    19621 tcgtgatgga agaaatgtct ggtaaaaact tgaatcattt aatgaacgcc gaaaacaaaa
    19681 ctgaaacttt tatcactgga attcaaaaca agcagctgaa acaagaagtt gcaaagcttt
    19741 tagttgagaa ctttatgaaa caggtgtttg atgatggttt tttccatgct gatcctcatc
    19801 cagggaatct gctattccat gtactaacaa aagaagaaca gacacaagct agccgaaaaa
    19861 ctgaaacagt ccatgaaaaa gagttcggtt cctttgcttt tcgagcctcc acttctgcag
    19921 aagaccctgt tgcgccatat accatcaact acatcgattt tggtatgatg gggcatcttt
    19981 ctgcaggact taggcaaaaa ctcacacaag ccgttttagc gctgtatacg aaagatgctt
    20041 atcgaatcga aaaagcggtc cttcgacttt gtcagcaaga aggctcgttt gatgaaagtc
    20101 ggttccacca agaactgaca agttttcttg aacagtatta tgattctcct attgatgaaa
    20161 tcaacttgca agaagtattc acacatgtcg tgacgatttg tcatcaaaat aatctgcagt
    20221 tcgatcgtga tatcacgctt ttgctgaaag catttgggac attagaaggg gtgatccgcg
    20281 tcctcgatcc tgaagtttcc ctcatggaag tcgcttcgcc ttttgctcaa cattattttc
    20341 tcactcatct ggatgtagaa gatacattga aacaaagcgg attagactta ttggaaggga
    20401 tgaaggctgc gcctaagatc cctcaacagc tccaccatct attagaaatg tggacttcgg
    20461 gacaaggaaa agtcaatttg gaattgaaaa agcaagacaa attattgagc aggatcgaaa
    20521 gtatgatcaa tcggcttgtt ttcggtatga ttttagctgc attgatcgta gggtcctccc
    20581 tgcttgtcca agcagcacct gtagaaaacg cagaggtcgt ttccttatta gggatattta
    20641 cgtatgctat tgccgcattc gtcattattt ttttggcaat cgatgcattg atccaaatgt
    20701 ataagaagag gaaaaagtag aaaaaggttg tgacagaaag aatcagcttc aagaaataag
    20761 aaggggtttt acataaattg tttctcaaat ttttgtgaaa attcggctta tttttcgaag
    20821 aggctacttc tgaaacaccg agaataaaaa atgtgaaaaa gctgttctgc acccagtaat
    20881 aagaacaatc aaaaagggaa catggaacac atttatcctg tttccctgtt ccctttttga
    20941 tgtattcgag cataaataaa ataccttcgt tacctactat cttctgtact tggtaaacct
    21001 tagtcaattg ccttttttaa cgcttgacga aaagacatat gatctttctc cgtaaagggt
    21061 tttggaccct ttgtccttat gccagctttt cttaactttc cactatgata acgttgttct
    21121 agaagcgtgc cgatattcgc ttcgtcaaat tcttttccag agtgatggaa cactcgcaca
    21181 cccttcggca atacaagtga agctaaacca taatcttgcg tgatcaaaaa gtcattcttc
    21241 ttaaccatac cgacgatttt ataatccgca ctatcagctc cgcggtctac gtagacgatt
    21301 tggacatgat tagcgtattc tttggtcgta taatggtcca cactggtcac gataaccacg
    21361 tcaagaccat aggattctcc taattttatg acatcttctt ttactggaga accatctcca
    21421 tcaatgaata gcctcattct ttttcgcctt cttccataaa tgataaacag ttactaatcc
    21481 gctcagtaaa agaccaacat tgatccattt tgccaagata agcagttgta cactttctat
    21541 cggcactgat tcatggttca gcgtgatcaa taatagatgg attggctctc ccatttcttt
    21601 tgctaaaaca aacaaaagcg tcatcaataa aaactggtgg atcacactcc ctttattttg
    21661 agtagtatac ttgacaacga tccggcgatc cattggaata gctgtatcag tttgataata
    21721 ttccttattt agccagctgc ctgttactac gtgccagaaa ctaagcagaa agacacctat
    21781 cgcaaaacca tttggaatca agaggaccaa taaagaagaa ctcagtccaa gcaattgcat
    21841 agccaatgga gaccatgtta aacgtttcaa aatccatggt ccgactattt ttgctgcaat
    21901 caagcctgct gcataaggca aatacataaa aatcgaaagt ttttctaatc cgtacagtat
    21961 gccaacataa aaactgctaa ataaaaaaag gaaattccct agcattccat ttagaaaagt
    22021 aaacagattt agccagcttg gcaacttcca ttccttcttc tggtgtccta aaacaaacac
    22081 gaacaagatg aacagcagca agaaaccata aatagcaaga tcaaaaagcc tttcatcgaa
    22141 taacaatcgg gcatttctca aaagaaacaa taagccaaag aatatcaaaa ataaaacaag
    22201 ctctcgcgta gctaccagat ttcttttgat gtctttgaaa tccagttcgt aacgcggata
    22261 atgactaacc gtatggtagg ccatgacgta aaaaagtgta taaatagtaa agcttgctgc
    22321 aatctgagtc ggtgcaggca actcaatcgc ttgatacagg agaaatagcc agatagctgc
    22381 aaataagtac tttttcccat ccatattgat aaaaccttgc gtcttttcgt gaaaattgac
    22441 cgtggtatta gcaggtacaa gccatgctgc actcagccct agcaaaacac ttgaaaaata
    22501 aaataaagga aaataaaata cgcctaatat tccaagcaat gaaccagcac caccaatcag
    22561 cagagcgatc atcagcaacg tgtaactatc tagaccaaat cgtagactgt tgactaaaaa
    22621 tagtccagtc atccgaaagg cataaaacag cgtaaatggc aaaatcgtca gccaattatg
    22681 cgagtctgtt agtcccaaaa ataaaagata aggaataaaa ataaccgtgt tacttaagat
    22741 aaagggcgtt gtttgtgtaa aattacgccc aaatcgtttg agtttttcga acatgacaat
    22801 ggctccttaa acagtcttat aactaatctg ctcttcgatt ttagcattaa aggggaaata
    22861 aaccaatttt acagaatata ttcttgtaaa aaaaaataca gaaagaagca taagcttctt
    22921 tctgcatttt tacggtactt gattactcaa gcagacaagc ccttctccac aaaagtcttg
    22981 cccgacaccc ctgcatccgg caggtgataa agatagaaat caattatcct gtgcctccaa
    23041 aatcaattag gagctctgta aaccagagtc cttctcgacc cgtcgcataa atttacttta
    23101 acacagttcc tatgtttatg cgagagcttt tttcatttta taatcgacca tttgaaatcc
    23161 ttgaccgata tctgaaataa gttcttctgt aatctcaaat ccttcatgct tataaacctc
    23221 gattgcttga tgattcccct gattcactcg caaaaagatc tctctttcct ttgtttgcgc
    23281 agcaagttct tcataccagc gaaaaactga agaagtcaat ccttgaccac gtactttatt
    23341 tagcaaatat aatttactta aataaatttt tccatttatc tcttcataag cagtgtaacc
    23401 gacagtcttt tcttcgcttt ttaataaaaa gtaggacaca ccttctgtca gttctttttg
    23461 aatctgtttt tttgactgat aagttttcag catgtaatcc acttgttttt gaccaatgat
    23521 cggcacaaaa acttccggcc atacttcttg tatgactgcc atcagctcat ccagttcatt
    23581 ttctgttact tttatttttt ccatacaccc acgtcctttt ttacattata aatgaccttg
    23641 cgcttgatgg aataaaaaga gcatgatcat gctatacaca cccaccgacc acggtttcaa
    23701 gaaaatcaca atctgcataa attccctaaa agataatttc gtcaaaccag ctactagaca
    23761 gatcaagtcg tctggcgcaa agggaagcag caaggtaaca actagtactt ttttaatatc
    23821 tttcgttttt cttgtcagca attcatcaaa tttctgatac ttttttggcg ataaaataag
    23881 ctggacaaag gctacgccat agtaacggac aagcaaaaat ccgattgctt ccccaatcac
    23941 taggccaata caactatata aaagcccaaa tccattgcca aacatcagca tgcccgctac
    24001 tgaggagatc cctcccggca aaataggaat gatcacttgg atcacttgca acagaacaaa
    24061 tatcatcact gcatacttgc caaattgctg gataaacgct tgcaaagacg tgctcgatcg
    24121 aaaaatccca tgatgataag cataaagaat caacacaaag aaaaaaaaca gaccaataat
    24181 gggcatgatc tgaagacatt tttgtaaaac tgatcctttt ttagacatct atattcccca
    24241 catctttttt catttattaa aactgcctcc tt
//
LOCUS       DAXLPC010000036        23739 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.036, whole genome shotgun sequence.
ACCESSION   DAXLPC010000036 DAXLPC010000000
VERSION     DAXLPC010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.036"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(74..376)
                     /locus_tag="ACF3UE_001404"
     CDS             complement(74..376)
                     /locus_tag="ACF3UE_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFD3634823.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(402..833)
                     /gene="ruvX"
                     /locus_tag="ACF3UE_001405"
     CDS             complement(402..833)
                     /gene="ruvX"
                     /locus_tag="ACF3UE_001405"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFD3634824.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(830..1096)
                     /locus_tag="ACF3UE_001406"
     CDS             complement(830..1096)
                     /locus_tag="ACF3UE_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFD3634825.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(1350..2075)
                     /locus_tag="ACF3UE_001407"
     CDS             complement(1350..2075)
                     /locus_tag="ACF3UE_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFD3634826.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(2441..2511)
                     /locus_tag="ACF3UE_001408"
     tRNA            complement(2441..2511)
                     /locus_tag="ACF3UE_001408"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2477..2479),aa:Gly,seq:ccc)
     gene            2628..3380
                     /locus_tag="ACF3UE_001409"
     CDS             2628..3380
                     /locus_tag="ACF3UE_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFD3634827.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            3396..3875
                     /locus_tag="ACF3UE_001410"
     CDS             3396..3875
                     /locus_tag="ACF3UE_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFD3634828.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(4126..5706)
                     /locus_tag="ACF3UE_001411"
     CDS             complement(4126..5706)
                     /locus_tag="ACF3UE_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFD3634829.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(5699..6442)
                     /locus_tag="ACF3UE_001412"
     CDS             complement(5699..6442)
                     /locus_tag="ACF3UE_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634830.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(6618..7394)
                     /locus_tag="ACF3UE_001413"
     CDS             complement(6618..7394)
                     /locus_tag="ACF3UE_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFD3634831.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(7642..8478)
                     /locus_tag="ACF3UE_001414"
     CDS             complement(7642..8478)
                     /locus_tag="ACF3UE_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFD3634832.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(8489..9418)
                     /locus_tag="ACF3UE_001415"
     CDS             complement(8489..9418)
                     /locus_tag="ACF3UE_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFD3634833.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            9610..9963
                     /locus_tag="ACF3UE_001416"
     CDS             9610..9963
                     /locus_tag="ACF3UE_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFD3634834.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(10037..10693)
                     /locus_tag="ACF3UE_001417"
     CDS             complement(10037..10693)
                     /locus_tag="ACF3UE_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFD3634835.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            10919..12853
                     /locus_tag="ACF3UE_001418"
     CDS             10919..12853
                     /locus_tag="ACF3UE_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFD3634836.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(12939..14162)
                     /locus_tag="ACF3UE_001419"
     CDS             complement(12939..14162)
                     /locus_tag="ACF3UE_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFD3634837.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(14156..16027)
                     /locus_tag="ACF3UE_001420"
     CDS             complement(14156..16027)
                     /locus_tag="ACF3UE_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFD3634838.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            complement(16048..17166)
                     /locus_tag="ACF3UE_001421"
     CDS             complement(16048..17166)
                     /locus_tag="ACF3UE_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFD3634839.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(17249..18082)
                     /locus_tag="ACF3UE_001422"
     CDS             complement(17249..18082)
                     /locus_tag="ACF3UE_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3634840.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(18075..18992)
                     /locus_tag="ACF3UE_001423"
     CDS             complement(18075..18992)
                     /locus_tag="ACF3UE_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3634841.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(19015..19194)
                     /locus_tag="ACF3UE_001424"
     CDS             complement(19015..19194)
                     /locus_tag="ACF3UE_001424"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634842.1"
                     /translation="MNKINENTSNTVLPATYSDATSYLTTAAYNYWQTGDFENSYLKE
                     AENFAHKYGVKLTGD"
     gene            complement(19219..20343)
                     /locus_tag="ACF3UE_001425"
     CDS             complement(19219..20343)
                     /locus_tag="ACF3UE_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3634843.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            20526..21434
                     /locus_tag="ACF3UE_001426"
     CDS             20526..21434
                     /locus_tag="ACF3UE_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3634844.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            21575..23188
                     /locus_tag="ACF3UE_001427"
     CDS             21575..23188
                     /locus_tag="ACF3UE_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3634845.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNNYTSARILAGLGIKAILIEE"
BASE COUNT         7392 a         4657 c         3966 g         7724 t
ORIGIN      
        1 gtgctaaacg aaaaaaccgg gctctacttt tcagagagtc cagcttttct tacaccttat
       61 cgattctttt gttctattct tcttccgcca tgaatgtatt gaatacttct tcgatcatat
      121 cccattctgc gtctgtttcg atttgttcta actcgccttc tgttccatct tcgttttcga
      181 tgtatgcata agcttgtaat tctacatctt catcttctga aacaccagct ggatataaaa
      241 gaacatagtt acgtccaaat tcttcttgtc cgtcaactgt tagcaagatt tcgtataatg
      301 tttcatttcc ttggtcatcc accaatgtga tgtgttcgtg tccttcgtgt tcgtgggaat
      361 ggttatgttc tgtcataaga ttacctcttt tctttttatt attaaaataa ttgcttacct
      421 gagccgtcta aataattttg taaaatcatc acagctgcta atttatcgat gacttttttt
      481 cgtttcgctc ttgaagtatt tgcctgctct actagcatac gttctgcctg aacagtggtt
      541 agtcgttcat cttgataatc aaccggcaag gagaatagtt ctttgatctt ctctccatat
      601 gacatggaag cttctgccct tggtccgatg gaattgttca tattcttagg taatccaact
      661 acaaaacggt ctacttcgta ctgcgccact aattccttca accgatcaaa accaaactct
      721 tcttctgcct cattgattcg aatgatttct actccttgag ctgtccagcc aaagggatcg
      781 ctcacagcaa cgcctactgt cttagaaccg acatccaagc ccattactct cataaattca
      841 ctccatgatt tgagaggtag tctttgacaa ttacttccat gatttcatcg cgttcgtgac
      901 ggcgaatcaa atttcgtgca tcacgataac gaggaatgta ggccgggtct ccagaaagca
      961 agtagccgac aatctgattg attggattgt agcctttttc ttccaaagcc cgataaacaa
     1021 tcgctaatgt ttcgctcact tcttttttgc gactatcgtc aaaaccaaaa cgtacggttt
     1081 catctgtaaa acccatgatt ctacacctct ttcccgcaag gtaattccag cttaccttct
     1141 acacccttat tttactcgaa gaaagggaaa actacaaaca aatattccaa acttctgaat
     1201 aaattaagaa acacgatttg tctgattttt ccttttttct gtggcttttt caaaagccct
     1261 ctttccataa agtatacgct atatttcttt gaaagtatgt ttttacacaa ttttttcata
     1321 aagttcataa aaaattcgaa ttgctgctac taatttttcg ttttcgttgc ttgccctgtc
     1381 tcataattga tggtgtagcc atcttgaaca ttgtagataa agacattgaa ttcaattttt
     1441 ttgtcttcaa tgctttctgc ttccaactgc acacctcttg ctaccagttc atttccctcg
     1501 aaatgaggag tgacacgata gcgtacatga tgatttgttt ccttgatata tgccgcaata
     1561 tcattttcgt gggcaagcat gtacggagca ttcaacgaac gtgtccctgt cattaagttt
     1621 ttaatgttat tattttgacc agtcaactgg aaaccaatca aatggctgcg gttgtataac
     1681 cattgtccgt cacttaattt cttttgtttc caacctgtcg gatcaatata caaaggttct
     1741 ctcttttcag taggaaacaa gtcttttccc aacatcgcat tggcttgtcc tactctgttc
     1801 aatttgtcta tatttgaata gctttcccat gtccctttgg aaagactaag atcctctttt
     1861 gtaaactccg gctgattccc attgatttct atttcttgat gttttccatc atattctggc
     1921 acatccgcta cttgagaagc ttgcggtgtg gaatcaaaaa tggttgtaat ttgttggaag
     1981 atatctgaat ctttttgtgt ggtggaaata ccgagtgccc ctgcaatcac agcagcgacg
     2041 atccccacga tcgccttggt tgtttttttg ctcatttctt tactccttta ctaacagttc
     2101 cctaaatctt aacatatgtt cccctataaa taaatactgg aaagaaatag aaacagtaaa
     2161 aaaataaaac cagtttttag acggcttaag aatacaaaaa aagagacgga ttcatcgtct
     2221 ctactcaatc acaaaacact atttacaagg tatttattat cattcaaaaa atttttctta
     2281 atactcaaaa ctaaacggct tctgtacgac ctcttggtaa acagtgttca aaagcttgca
     2341 tctgcggtaa taagtccaac caagtcaaaa acataagaag cttttttgct tgactattct
     2401 tattacttga tgcagggcag ctttttcaca gcctctttta agcgggtgac gggaatcgaa
     2461 cccgcgacat cagcttggga agctgggatt ttaccactaa actacacccg cgatacaaaa
     2521 acagtatacg cctctttcac tccttcctca agttttttta ttctttacgc ttccgatatg
     2581 ttttgtagta aaataaaact aatcaatcaa ttattggaga agatgctatg acgggaaaag
     2641 aattagatct gttgctggac acttgtttac tcgctgggaa aatcatgatg gaaagcaatg
     2701 cggagatgta tcgggtagaa gatacgatga gtcgaattgc tttagcttct ggaaatttcc
     2761 gtttggtcag ctatgtcact caaaccggtc tctttattgg tcttgatcgt acctcgacca
     2821 tccgaatgga acaaattacc aaccgttcga ttaatttaga aaaagtagta aaagtaaatg
     2881 atctttcacg taaatatgtt gcttcagagc taacattaga agaactttac tgcgaactgc
     2941 aagcaatcga ccgagaccgt tctttctttc ctgtctggtt gcaaatcgtt agcgcggcag
     3001 tgatcagtgg aacaattatg gtgttatttg gcggaaagat gaccgattta cctgtgactt
     3061 tagtcattgg aggattggga tacgcagctt atctatatag tttgaaattt tttagaatca
     3121 aatttttatc ggaattttta tcttctttat tgattggcat agccgctatc tacagcgtac
     3181 gttttggctt aggaagcaat caggatctaa tcattatcgg atgtgtgatg cctttagttc
     3241 ctggagttca aattacgaac gctatccgtg atttgctagc tggacattat gtctcaggag
     3301 tttctcgcgg aacagaagcg atgatgactg ctacgatgat cggttttgcg attgctttta
     3361 ttttccagct tttttattag gaaaggaaca caagtatggg gacgatattt attcagtttt
     3421 cttttagttt tttagcgact gcggcatttg ccgttattac aaatgtacct aggcgttcat
     3481 tgatttgttg tggtctttct ggtgcttttg gctggatgat ctactggatc tgtgttcaaa
     3541 taggcggatc tgctgctttt ggttcattgc ttggttcttt aggagtagca ttcatcagcg
     3601 atcttttctc taaacgtttg aaaatgcccg taacgatttt caatattccc gggatggttc
     3661 ctctagtccc tggtggttta gcttatcaag cggttcgaaa tctcgttact gaatcctatc
     3721 gagaagcggc tcattatgcg gtccaagcaa ttatgattgc tggagcaatc gctttaggtc
     3781 ttgtattatc agaagtcttt aaccataaca tccgtaattt caaagtaaag cgtgacgcaa
     3841 tcatgatgaa acgaaaaaaa cggcttttta aataaacgaa gtgtaacaaa gaaaaggttg
     3901 tgaaagagac gttcagcctt gagcgatgac aaaatatctc acaaacattg cgacaagtaa
     3961 ccgcaggagc aataagaagt aattatgagt attaaaaaaa gttttgtaaa aatagcttct
     4021 cacattttta cataaaattg acttaatact gagaaactga cttttgaaca ccctctatct
     4081 gtaaaaaagg ggctgcgaca tgatttttgt cacggcccct cttctttatt caaatttttt
     4141 ccaaaacgtt cgttgataat aaacgatcca tagagcggaa agtattagaa ctaaaccgat
     4201 cacaggaata ttcactaacc aaaatggata aaacaaagcc aacattccgt ataagacgat
     4261 aagaataata ctgatgatca atgaacccat catagttgcg actaaaccca aacttcctga
     4321 acctctgtta aataattggt taatattggt ccagttcagc agcagcaacc gataatctct
     4381 agcgaaataa cgtagtgaca ataagtagca gccgaataaa gaaccaaata gcaagctagg
     4441 gataaaaaac aaaggcagct gaaaagacag tccgcttaat aatgcgatcc caccagttaa
     4501 aaaactctgc aatatccatc cgaatctgaa cttttctttt aaatattggt tcatagagat
     4561 tggcaaagaa cggataaaca gaaaattttc ttgatccaaa gaaataagat tgctgataaa
     4621 agaagtctga ttaactgtta agaaagccaa tgcgatccct accaggaaaa caacaccgat
     4681 taacttatta tctaaatcag ttaattttat ttcgcctcct agggcaaaag caagaataaa
     4741 aatgattgga gttaacaagg aagaagaaag aacttgcata atcaaattag gttcttttac
     4801 taattgagca ttgtaactaa ataaaagctg atgcacattt tggttctttt tatgggttct
     4861 ttttattttg aactcactgt ttgaatcagt cagttgctct gtaagctttg gtactatcag
     4921 ctgttttaca gcaaggaaaa atcccagagc cgtgatagct agtattcccc aacccaataa
     4981 accttgttga gaaagtggct gactggcagc atcatagaat ggcaataata tcgaaatcgg
     5041 atgccgatct gttaactcat tttcaatagt ccccgtttga tgattcatcc acatgattcc
     5101 agcaaatgcg atcagcatcg agctgccaag caagatacta gaaactgttt ttctatgttt
     5161 tttaaacact gctgttcgag ccaaaccaaa aacaatcaaa ctagccagac aaaaaagaat
     5221 aatcaaaaat agagaaaaca aaaggattga gataatgata gtaagcaaaa tccctagatc
     5281 agctcgccat ccggttaaaa taaacatgac tagaagcgga aaaacaaaag gaatgatggt
     5341 caaagcaact accaaaatct ttgctgaaaa aacctgttct tgtccaaaag gcagaggcaa
     5401 aaatacttgc aggtcatttc cttcaaaaaa gatattataa atgactgata tactttgagt
     5461 taaacctaac ataccaaaaa gtgccacgta ataagtaaag aaacctggca atttaacaaa
     5521 gttcatagca aacatagcaa atccgtaaat cagtaaaaaa atcagccctg aaaaaagatt
     5581 ttgagacaaa agatagatag ttaatcgctt tccctttttt cctttctctc ttgctttatt
     5641 cgtgagctgt ggattaacat ataaaagatt aactcgaatt aattctaata attgtcgctt
     5701 atacatacgg tccatctcct gtcgcttgcc ttccagccat tttcaaataa atcttttcta
     5761 gcgtttcatc aggtgagcca ttcaataatt cactaactgc cccctgataa atcaattcac
     5821 ctttcttcaa aatagccagt ttatcgcata actgttgtgc ggtatccaat acatgtgtag
     5881 aaaaaatgac tgtttttcct tttgcggcat gagccttcat catttctttc aaatcaaatg
     5941 ctgcttgagg atcaagtcct tgcaaaggtt catccaatac ccaaatatct ggatctggca
     6001 gcaacgtgcc gatcaaaatc gttttttgac gcattccatg tgaaaaactt gcgattgttt
     6061 cattttgatg actatacata tcaaaaagcg ctgtcaattc tgctaaacgc ttttcttttt
     6121 tttgtgtgtc taattcatag gcagctgaaa tcaagtccca atattctcca gccgtcaatt
     6181 gtaaaaaaat atctggggaa tcaggcacat aaccgatttt ttgtttgata ctcaatcgat
     6241 tttccgtcaa tttcattcca tctactaaaa tcgttcccga tgatggttca ataatactaa
     6301 ctaaactttt aatcgtagtt gattttccgg caccattatg tcctaaaaat ccaaaaattt
     6361 ccccttgtct tatcgagaga gacaagtctt ttaatgcttg ttttttcccg taacttttac
     6421 ttacattgat gaattcaatc atttctgtac tccttttgtt tgttattact ttttattgta
     6481 cccttcgtta ttggtggagt aaatgtcaaa aagagtgcat aacaaaaaag gatagaaacg
     6541 actaggctgc tacttgggtt gttctcttct acaggaaaac actcttctaa caggtaagat
     6601 atgagtcttt gttttcttta aaatgattca ttttctatct tttcttgcat aaaattcttt
     6661 agtttatcaa tacttctctt tcccatctct agttgttctc catttgcaaa tgttactatt
     6721 tcgtttactc tgctaataga tgtaatgttt tcagtattaa tgatataagc ttttaaatct
     6781 ttacataaat actcatattc gagtgatttt ttatattttt taattgtgcc gtttacgaga
     6841 atctcttcat ctttcaatac taggcctatt ttatttttat aacctggcat gctcattaga
     6901 taaaggattt catcgtaatg gatatagtga tcgctattac cataacggac agttgtccac
     6961 ctttttttcg tagcatgttg aacaggatag ttttcttttt ctttcaataa gtaactttgg
     7021 atgctttttt tatttttttc ataagtgaat tcttttatca aataaccact aggcgtaatc
     7081 tttcgattaa taacagttat tgctttattc ggatgagacg ttagataaac aattttacac
     7141 ttttcattct tttctctaag catttcgcct agttcgatac cgctataata ggcgttcaaa
     7201 tcgatgtcta ggaaaaaaat atctgaggaa tagatttcat tatttttaat gaattcaaca
     7261 aattgtataa cgttcaatcc ctgaacgatc tcaaatttcc aaggacttaa taaaattctg
     7321 gattcttcca aaatttctac tagcattttt tcaaaaacca aactatcatc caaaataaat
     7381 atacgcgtta ccataaaaag tacctccact cgatatttta ctatcaaaat catttcatac
     7441 aacttttcaa catacatgtt aggaataaat tgtaattctc ttcacaatct tttccaacac
     7501 ctttgaaacc gatatcaaat actttcagga tgctgcttct aaaataaata tcaaacaaat
     7561 gaatacatca tgcaaaaaaa gccagacaac cgacgtcctt gcgtgtcagc tgtctgagct
     7621 atgtttattt attttgttct tttaaaaaga acgatacaca tactgatttt tcggagcaga
     7681 gactttctca gcgtttgtaa caactacaga tgggatttca cgcttgaatg gttgataata
     7741 gtctgattgg atggttcctt ctattttata ccattcatca tttttaaccg ttactccttc
     7801 cggcatatgc gtcaacaaac caaagactcc tgaatctgcc acacaatgga taatgccgaa
     7861 tcggaacaag aagatatctg tattgctatc gttcggtgtt tggtaaacaa atccttcata
     7921 gctgattttt ttgccaatga attcgctagg gtaattataa attagctcca taacttctaa
     7981 atagttttca tctgtgatct tgatagtttg cttatcccca tacttttctt tcaactcatt
     8041 catttggtct aagtagtctg atttgttgaa ataaatactg gtatccggct ttaagtattg
     8101 tgtctgcatc tccggatccc ctactgattc tttacttact gggaaattaa atcctttggc
     8161 ttctacgatc gtagtgtcga gactaactgt tggaaacaac gtccccacga ttactggcaa
     8221 agctagcagt acataagcga ttccacgttg ataaggtttt gacaacccat ggtcatgatc
     8281 gtgctcgtgt gccttttctt ctgcttttcc gtttttgacc cacaaataca gctgaactaa
     8341 agccaaaaga gcagataaaa tcattgaaag aatagctaag tagcgataat ggacattgat
     8401 atattgatcg agtttgccag aaacttgcaa gtacatcatc aattcgaaat acccagataa
     8461 aatcaaaaac cgcagcatat tttccctcct aaataaataa tgtgaatcca ataacgctaa
     8521 gggcaatcag tccgatcagc gataaaataa agcgtcctgt aaaatatcgt ttcatcatca
     8581 gtagattttt gatatcgacc attgggccaa agaccaaaaa ggcagctaca ggtgctgtgc
     8641 cgaacagact taacaaagaa gatcctataa acgcatctgc ttctgagcaa agagacatcg
     8701 taaaggccaa taacagcatg atgataatgg ctaaaatctt tgttgagccg agcgttagca
     8761 taattctagt tggtaaataa gtctgcatcg cagctgcgat taatccgcca atgatcaaat
     8821 aacgacctgt atcaaaaaat tcgtcgattg aatgtgtcaa cacatgccca gtttgatgga
     8881 tcagctgatt ttttggttca ttcttctcac tttgttcttc ttcatggaca tgatgatggt
     8941 gattttctgc tactttagac gtgatttttt ctttcaatac agcgtctttt tgaaaatagg
     9001 caagccagac accaatcaca agggcaacaa aaaagctgcc tatcacccgc cagcttgcca
     9061 tctgccaaga attgccaaat gcgataaaag tggaaaaaat cacgattgga ttgatgatcg
     9121 gagcagtcag cataaaagca aacgctgtgt gaactggtac gcctttttta acaaattgat
     9181 gaacgatcgg tacgatgccg cattcacatg aaggaaagaa aaatcctaag atcgaaccag
     9241 taaaaataga gaagatacga ttttcaggaa gccatctctt cacacgttct ggggtcaaaa
     9301 atacttgtaa ggcgcctgag ataagacagc ctaataatac gaaaggtaat gcttcaataa
     9361 cgatcgataa gaaaatcgta ctcatctgca aaaccgaatt tggaataaaa gaaaacatga
     9421 gtttcctcct ttttatttct agttcattcg ctttgcaaat atacgctttt attcaaaaaa
     9481 aacaagttgc tctgtaaatt tttacacaac tcttattttt taccaaagca cttcaattga
     9541 ctttttctgt tattcccatt aaattaaggt ctcatacata tcacttctat cataaaaggg
     9601 agaataaaaa tgaaacaaac cactaacttg actgaagttc aagacatact gcaacagtca
     9661 tccgttgccg tcatttatct ttcgatgcct aattgcagtg tttgtcacgc tgttcgtcca
     9721 cgactagagg aacttctcac acattatgat attccggcac ttcatttgga tgcatttgaa
     9781 acaccagaag tagctagtaa atttgaagtg ctgactgcgc cagttgtcct gatttttcat
     9841 caaggaaaag aagtctttcg gcaagcacgg ttcatcgact ttaaaaaaat ccgttatcta
     9901 ctagatgaac tgacagcaga agatgattcc ctttcttatg aagaaatctt ccgaacaaaa
     9961 taatcgttgt ccaaacagaa aaaagcgatt gaacaagtga aagttttgcc ttcatttgtt
    10021 caatcgcttt ttatttttat tctgctgtat tttcggaatg cgcatttgcg tcagaatgca
    10081 agaaatagat caaggtttgc aattcattcg tcaaatcaac attttggatc aatacatctg
    10141 acggagcatt caatcgagca gcggtaaagt tcaagattcc tttgattcct gcttccgtta
    10201 actgattgac tacttcttgt gctctttcag cgggtatcgt taaaattgct acttcgattt
    10261 gttggatctt gatttgttct gacatatctt ccattggata aacggggata ccgtctacga
    10321 tgcgcccaac gatttcctca ttcacatcaa aagcacaact gatacgtatg ctattacttt
    10381 gatggaattt gtattttagt aaagcacttc ccaagttccc tacaccgatc agcgcaacat
    10441 ttgtcaattg atcgtcgttt aatgtctttg caaaaaagtg cataagatct tctacatcat
    10501 aaccataccc acgttttcct aattcgccaa aataagaaaa atctcgacgg atcgttgcac
    10561 tatctacttg aacggcttca cttaattcag ttgaagacac ttttttcttt ccagcattat
    10621 ttaaaatcct taaatagcga taatacaaag gcagtctttt agctgtcgcc tttggaataa
    10681 tatgatcttt cacgaaatga cctccacgta ttgtctaatt acatctttga tttctccatc
    10741 atagcagtat ttataggaaa aaatcaattc cattgctcag atattgtgaa attttattct
    10801 ttattcattt atttatcatt tctgcaaatc tcgcagtata atggaattta tggtagacta
    10861 ctaattgaaa aatagttttt tatttgagga gaattcacaa agtagaaaag aggattccat
    10921 gatattatta caagccaatc agattgctcg ccattttggt gcagaagtct tatttgaaaa
    10981 catacattta gaaatcagta caggcgctcg tgtcgcttta gttggcagaa atggcgctgg
    11041 aaaatcgact ttattaaaga tcattgctgg aattgaagca cctgatgaag gaaagatcgc
    11101 taaaaataaa acagcgactc tcggatacct cgctcaggac acaggacttg attccaatga
    11161 aacagtttgg aacgagatgc tgaaagcttt tgaacaagtt agacaaatgg aagagcggat
    11221 gcgcgagcta gagattttca ttagcgaagg tacgccagac acacctgctt atagttctta
    11281 tttaaaagaa tacgaccggc tgcaacacga tttttcagat cgaaacggct atggttatga
    11341 aaatgaaatt cgttccgtat tgcatgggtt taaattcgat tcttcatttt atgatcagaa
    11401 aatcgatact ttatcaggcg gacagcgcac acgtttagct ttagctcgca tgcttttgca
    11461 acaccctgac attttgattc tagacgaacc aacgaaccat ttagatatcg agacactttc
    11521 ctggcttgag aattatctgc aaagctatac tggtgcatta ttgattgttt cccatgaccg
    11581 ttatttttta gataaagtag tcaatgaagt ctatgaatta agcagaagaa aaatgcgcca
    11641 ttacaaaggt aactattcga aatatctaga tttgaaagca gaacagttag caagtgaatg
    11701 gaaggcttat gaaaagcagc aaacagaaat ccataaatta gaagacttcg ttgctcggaa
    11761 ccttgttcgc gcctctacca caaaacgagc gcaaagccgc agaaagacat tagaaaaaat
    11821 ggaccggctg gatcgtcctc aaggggatga aaaacaagca aactttctat tcagtataga
    11881 aaagccttct ggaaatgtag tcttgcaaat cgaagatgcc gctatcggat atgataatgt
    11941 caccttatct gaaccaatca atctagatat ccgtcgtcaa gaagcgattg ctctagtagg
    12001 tccgaatggt atcgggaaat cgacgttgct gaaatcaatc attcaccaga tcccttttat
    12061 ccgtggaaaa gaaacgctag ggacaaatgt caccatcggc tattacgatc aaggtcaagc
    12121 tgatctgcat acaaacaaga cgatcctagc agaattgtgg gatgagcatc ctaccactcc
    12181 agaaaaagag atccgaagtg ctttaggtgc tttcttattt tctggcgaag atgtagaaaa
    12241 accaatccct ctgctaagtg gcggtgaaaa agcacgggtt gctttagcca agttagcgat
    12301 gaacaaagaa aattttttga ttttggatga accaacaaac catttagata ttgacaacaa
    12361 agaagtatta gaaaatgcat tgatcgatta tgacggcaca ctgctttttg tttcccatga
    12421 ccgatatttc atcaatcgga tcgcgacaaa agtcgtcgaa ctctctgaaa atggcagcaa
    12481 agtctatcta ggagactatg attattattt agagaaaaag caggaagaag aagaaatcgc
    12541 cgaattgttg gcacaagatg agccagaatc tgctcctgct cccacgaaca aatctgatta
    12601 ttaccaaagc aaagaacagc aaaagcttat ccgtagcctt caacgaaaaa ttactcaggt
    12661 tgaagaagaa atggcgcgga tcgatgaatg gatcgatcag ttggaacaag aaatggtcgc
    12721 gccagaaaac ctggaagatc acgtaaaact caatgagctg aaccaagatt tagaagctgc
    12781 tagacaagat caagaaacaa aattgacgga atgggaagaa ctaagcttgg aattagaaga
    12841 atatgaaaat taacgaaaaa accaaaacag aaaccattca tgctgttttg gtttttcttt
    12901 ttttatttta tcaaacaaaa attccatatt tacctttttc accaataaga agaccaatta
    12961 ctagtcattc tcactaaagc ttctaaataa tagtaatcac cccaaataca aggtgtattt
    13021 accccattat ttttgggctt attataaaca gactgtgtta aaaagccatc ttcttcttcc
    13081 gttgtagcat atctttcttt caattgtcgc ataattttcc aaacagcaga ctggtataag
    13141 ttcttttctg ttttgtctaa tagacctgat tctattaatt ctaataatcc acaaaccatg
    13201 atcaccatac tagatgtatc tttttcttct ctgctagaat catcaaagat caaatcccaa
    13261 taacaaatgg tatcttctgg caaccgattc ataaaataat tggctaatat tttgcttaaa
    13321 tcaaaatatt tttgttcttt caaataacga taacttaatg caaaaccgta aatcccccat
    13381 gcttggcctc tagcccaaca ggaattatca ctataacctt gatgcgtact tccatatctt
    13441 ggttttccat ctttgacatc catataaaat gtatgataag ttgaaccatc ttctcttact
    13501 aaataatctg ctgcattttg aatatgagcc tgagcagctt ttttatattt ttgatttcca
    13561 gtttcttcac tcgcccaata caataatgga agattcatgc aacaatccat gatcattcta
    13621 ccttgttgtg aaggatcact aggatctccc caagcttgta taactcctgc cttctcccaa
    13681 aaacgctgaa gtaatgtttc tgcagcatca attgaagctt ccttcatttt tcgatttccc
    13741 gttattttat aatctgctac ggttgataaa gaatacaaaa aaccaagatc gtgatgatta
    13801 gtgataattt gacagtcaat cctgtggata aaatctatat ctgctttttc agctgtttgt
    13861 tgaaataaag gatcacccgt cttctcaaat aacaaccaat taattcctgt ccaaaatcct
    13921 tctgtccaac caatattgtc tcttaatgga taacgtcctt ttataggaca ctcgcttggg
    13981 aattgatact gactgttact gatacgtttg attaacctct ccgtgtgtct gcgacaacgc
    14041 tcgatctcat tattccattc tttttccatt aattctttat aacattcatt tatccatttt
    14101 tctggatgta ttatctcttc aaacatcact ttatcaagca tttccccacc agcctttagc
    14161 ataattttag tcttttttta ttgtttttat tttggatagt tagcccggtt gtcccatcaa
    14221 aatcaatttt gggacgattg ttccatactt ctaaactata atcccgatct tgatgagcaa
    14281 ccactcctgt tccgagccaa tgggttcctt ttccaaatgt accctctaat ccaggaataa
    14341 aagtgttttc ccatgtcatc aagtttgtat tgggcaaacc cataatagct gtggattttc
    14401 gtttaatagt atcgtcactt aaacagataa tacctgaaaa gccagcttca ctcaccctat
    14461 agttttcctt gtcttcttct atgattattc cttctttctc aggagaacat tcaatagcaa
    14521 accctgtctc atatagaaca tattctgtat ctaattctac tttgtgtacg cgaatctgcc
    14581 agccttcaaa aggaataagc caagttctga tttttgcctg taaagtaggt tcccatgtag
    14641 aggcaagtac ctctttctta catacaatgt ctcgtacatt atttcgaacg atgaactgtc
    14701 cataggtttt gatgctctca ttcttaaaac tggtcgtgat atatgtgtcc gctcgctgaa
    14761 tccctagcat tgaatccatt gccatttctg ctttcaattg attcgctcgc ggtatcgaaa
    14821 aaccaaattg actagaataa gcaaatttta aatatttttc attggtcaat gtatggaaat
    14881 ttggccctaa ttgtcccgca ttcaaaaaaa atgtatgtcc attatcatgt tgtatgagca
    14941 aattggcttc tgaaagaagt ttagttcctt cacgaatagg cataggcatt tctttagccg
    15001 tccaatactc atggtcttca ggtagcgcca acaataaaaa aatcttattc agccataatg
    15061 gagataacgt actattatag ggttcagtca atgtcaattg agggtaggta taaccaatat
    15121 tcaggatacc tttttcatca aatatttctt tttgcatcca ccatcttata ttccgattga
    15181 ctaacccctt gatttcacct aatttaaaag gcaaaagatc ggcccacaac atagctgacc
    15241 aaaagcttga aactgcaaaa cgataaatca tgcttcgacc aaaaggcaca tttgcaccat
    15301 cttccgcaaa aaaatgaata tagtctctag aaaaatcaat agctcggttc ttatatatct
    15361 ggctaatggg cttttctggt tctagtacgc tataaatcaa accataataa tgaaatgcaa
    15421 aaggattata ataatcttgg cgacctcttg aactgtctcg ataccagcca ttttgaagat
    15481 aacaattttc tatattatca aatgcttctt tcagtgctga ttctttaact ggataaccaa
    15541 atttttggat aattgttccg acaattatct taaaaaattg ccaattacca tctgcacatt
    15601 catattcaaa aatttgcgag aaccaatgaa taatctggct tttttctcct gtatctaatt
    15661 ttttccataa taattgttca tgatgatata acgctaataa cattgcgggc atttctacca
    15721 tacgctggtc tctttcatgt atttctcccc aataatcggg atgggaagga tctgttccag
    15781 cttttattcc tgatagaatt aatttcaacc atcgttcatc taattggtca attgcgggcc
    15841 ccgctcccca taaaacccga gagaatcctt ccattcctgc aattttattt ccatatccta
    15901 ccccttgatg tatataatca atttgtgcgc cacttgctcg ataaaacggc tggagtggtt
    15961 gatttatctt tttaaataag tcaaagtaat cctgtctggt ccttaatagt ggtactggat
    16021 gtttcattgt attttctcct ctttttacta ccaaatagct aattccgact gttctaatcg
    16081 aagtaagcct tcaataaaaa aataatcaga atagatcagt ggcacattat aagtcagttc
    16141 tctatggtat gcttctgctc cgcctccaat gatcccatct tcatccatat tccaatttgc
    16201 atagtgcttt tctgtctttt ggagtatatt gatagcagct tcatgataca tttttgatcg
    16261 tacagaggaa acatatcctg ctaattccag aagaccgcat gcagcgcata ctccagcact
    16321 ggtatcaata ttcgaatctt ttacagcaaa atcaatgaga ggaatataac cagttttttc
    16381 gattttctga ataaaattta ctgctatctt ttctgctata gctagatagt acggattttt
    16441 tgtgtaacga taacttaacg cgaatccata taaagcccat gcatttcctc tgctccaaca
    16501 agaattctca ttgtatcctt gcccgccaag taaccgaata tatttccctg attctgcatc
    16561 aaattctgcg atatgcccgg ttgatccatc tttcctcact agatacttag ctgttgtatc
    16621 tgcatgctgc cgagcaattt tagagaacct cggatcacca gtttccctcg aagcccaata
    16681 cagtaatggt aaattcatca tactatcaat aatcatccaa ccaggtttat ggtcattcca
    16741 tgctactaaa tagttccctg aaatattata gcgtccagca agtaccgtag ctgcatgtaa
    16801 ccctagttgt cgactatgtt tgttttgaga ctgttgataa tgtgcaatag ccgatggtaa
    16861 gaataaaaaa cctacatcat gatgaacgtc tgaaaaatgg tacagggcag attctaataa
    16921 ttgttcttgt tgtattgctg cctctttgaa cttttctcgt tttgtcttgt gaaagagctg
    16981 ccataaaata ccactccaaa aaccattggt ccaccagtcg attcctctgt cctttattac
    17041 gtctgtatat tttccgttgt aagaaatata tggaatttta ttccccattc tgtctaattc
    17101 cgcatctatc ttttcagaag ctacattcaa aatttttctt gaccattcct tcgtctgttc
    17161 attcatggat atcccgccat tcttttaatt tttatgaatg tggagttgct cctagaacga
    17221 actagatggt taacattcgt tatttttttt acttatttgc agctccaatg tcattctcct
    17281 taaatttaga ctgcgcccac acataaatca agaccattgg gatcactgaa gttgctaaaa
    17341 ttagcataat tgcgccataa ttaattggct cacctgtact agaaaccgtc atatttttga
    17401 taattaaggg aaccgtatat ttatctttat ctgaaagcat gactaatgga aatagatatt
    17461 gattccaact tcccataaag ataagtaaac cactagtaat aatcgtaggt gataaaatcg
    17521 gtacagcgat tttcgtaaaa atcacccact cattggcacc atcgattctg gcagcctcca
    17581 tcagtgctgt aggaaattga ctgctatatt gtcgcatcat aaacactgaa gttgtactgg
    17641 caatcgaagg gatgatcaca cctgcataag tattcgataa tcctaaacga ctcataatgt
    17701 aaaataaagg aatcaatgtg gtaaaaaaag gcaccatcct agatagcata actgtattga
    17761 acaacagttt attccccata aaacgatact ttgctaatgc ataacccgcc attgtagaac
    17821 tggctgtagc tgaaactgta ctgattacag caataacaat cgaattccaa ataatcaagg
    17881 gataattata tctcgccatg atggcttgcc agttttttaa tagcatatcc ccaaacttga
    17941 aattgattcc gccacttaaa atttcttgat tactttgcgt tgaagctaca atcatatata
    18001 aatatggcat caaaaatatt aaggcaccaa acacaataat gacgtacgta aaaattctgc
    18061 tttgtatctt ttgtttagtc atttttatca cctccgaatt taaattgaat agccgataat
    18121 ataacagata caaacaccat cgtccaggca atagcagagg cttttccaaa atcaaccatt
    18181 tcaaaacttg ttttatataa attgactcct acgaccaaag ctgaattttc tggtccattg
    18241 gaagtcccaa agaatatatt tgggatattg aaattaccca agccattgat agtggctaaa
    18301 actgtggcca ttaaaatgat tggctttagc atggggatcg ttaataaaaa gaattgccga
    18361 aatttcgatg ctccatctat ttcagcactt tcgtatatct ctttagaaat cccttgaaga
    18421 ccagctaaaa ataaaatagt gttatatcct acactaagcc aaatcatcgt gatgatcatt
    18481 gatattcgta tccaaaaagg atttgttaac cactgtacac cgttaattcc tagcgcattc
    18541 aaaaatccat tgaataaccc agtcggattg aaaaaagtca tgaatacgga agctacagcc
    18601 accgttgatg taatggttgg aatataatag acagttctaa aaaatccttt tccttttaac
    18661 tgtgctgaat tcaataaaac agcaaagtaa atagctaata gcatcgttat tggaattgat
    18721 cctgccatga taatcaaaac attcgtgtaa gatttaataa acaatggatc tcggaagata
    18781 gctagataat tgtcaaatcc aacaaattca aatgagtagc caattttcat aaaactaaaa
    18841 gcaaacgaga taatgatggg aatcaaaatc gtcacaataa agaaaataac aaaaggtgtg
    18901 accaatccat aagcactttt tttatgagac gtatctgttg cttttttctt gctgttcttt
    18961 attgtcttgc ttggtaacga agattgcatc atcgttaagt cctcctaata ttttttaatc
    19021 accagttaat tttacgccgt acttatgagc aaaattttct gcttctttta gatatgaatt
    19081 ttcaaaatca cctgtttgcc aatagttata tgcagcggta gtcaaataag acgtagcatc
    19141 tgaataagtg gctggtaaaa cagtatttga tgtattttca ttgattttat tcaatagttc
    19201 atagtatttt tgtcctcctt agtagtcaaa ctttttctca gctgcttctg tttgataggc
    19261 caatgagtta gatgtagcca cgcccagctc cagtgcgttg gctaagcatt cttcatctgt
    19321 cagcataaat gtaagaaatt gttgtgccac ttgtggattt ttggcatctt tagggacata
    19381 aaaacttgat cctcctgata ctgcaccttt tcctggattt tcttttgaaa aaggaatcag
    19441 tggagccatg cgccatttgt cagatgcatc aggaaaattc aaagacatat tcgtagcata
    19501 ccagccgcca gcaacaaaca ttgcagattc ttgaaatgct ttctcagcat cttgtgcacc
    19561 gtagaaatgt acaatatctg agtcgatcat ttctttgatt aactttgcag catgtttcgc
    19621 ttctttagta ttcagacgga tatttccttc ttcatcaagc aaagattgat tctgctgggc
    19681 tagcatgttg ataaacaatt cttggtcccc agattctggc aaggcaattc caaaactacc
    19741 agttttttct tttaatgctt ttgccacctg gatatattct tcccaagaac tgatttcttc
    19801 aaaatctaca cctatttcag caaatttttt tggttgataa taacaaagtg ctggggtaaa
    19861 atcactagcc caaggaataa tcgtttcatt actcgtttgt tgacgcaaaa tattcaattt
    19921 ttgatcataa aactgatcgc catatttgtc ataaaatcca tattcatcag cactataaaa
    19981 agcatcttga aatttttcca gcacacctgc tgctgaagtg tctgccatgg agataatatc
    20041 cggcatatct tcgtgtgtta ccaattttgg ggtgatcatt tgtactgttg ctgttcccga
    20101 agctacattc acaattttta agtcaatatt tgctccagtt ttgcggttat agatttttgc
    20161 agcattttca acatagtttg tcagtttgcc gtttgcgaca tatacttcta atgtagtggc
    20221 tttttttatc attggatctg cgatgtttgc tgttacttct tcgttagttt ttccacatgc
    20281 acttaagctg aataataggg taatgtttag caaagctatc accaatttgt atcttttttt
    20341 catgtctatc ccttctttct tttcaagttc ttatataaaa cgctttcact tatgtatatt
    20401 aacggaatta gtaacacaaa tatttatata aaaaaatatt ttacttgtcg ttttggcttt
    20461 tcatttttgt tataatagtc attaattata aatagaaagc tttttatata aaaagagaaa
    20521 ggaaagtggt tcttttgtta acaaacaacc aatcctccaa tcttgtcaaa aaaacactaa
    20581 cctattccat agatacccat cttcatttat ctgctgctcc ctattttcga ctactaataa
    20641 atgaaagcgc taatttatat gctgaatttg cacataaatc tatagaacta gataatcctt
    20701 cccttttatt cattgataaa cagcaagaag tccaaatctt ttctactcaa aaggaaacac
    20761 aaacttttat cattatccag ttttattttg atgagcaatt attagcacat attacgggac
    20821 aatctttttc tatagatcaa gaaataacat ctatcattac ttttctgaaa aatgaacagt
    20881 tcaaaattga ttatctaaaa catagtaagc cagctatttc ctatgatcag gaaatcaatt
    20941 cttttttcat actatgccaa cagatgagca ttcatttgct ttccttatta gttacttatt
    21001 gtctgcaaaa aattcaattg tcttccttac caaggcatta tcaacaggaa cttgctttat
    21061 tgacaatacc ttcaaatgag aaagtcattc ctaaaaaaaa gcatattctt tattcagatg
    21121 aattagttga tccaatcata cgatatttag aagaacatct ttcagaaaat tttttgcttg
    21181 aacaattagc ccaaattttt tttatcagtc cagccagctt aaaaaaacat tttagaaaag
    21241 tgaatggaaa aagtgttatt agctatttta aagaactaaa aatggaaaaa gcaaaacgtc
    21301 tcgtgctaga aaatgaatta acctatacag aaattgcaga tatattagga tttcattcga
    21361 tccatcattt ttcttcagct tttaaaaaat atacagggtt atccccttca aagtattatc
    21421 tatccttaaa atagaaaaaa atttttaggt tttatccaca aattatttct ctatattttc
    21481 tgtctattca aaataaacaa taattttccg gcacaattat ttgctgtttt ttaccataac
    21541 atagtacgat caacgtagaa aaggagatgt ttttatgaaa gttgttgtca ttggcggtgt
    21601 agctggcggt ccttcatttg ccactcgttt ccgtcgattg aatgaagcgc acgaaatcat
    21661 tatctatgaa cgcggagaaa atatttctta tgcaagttgt gctttgcctt attatttagg
    21721 aggtgtgatc actgaccgtg actcgctgat cgaacgtaca ccagaaatat tgaaaacaaa
    21781 aaacaacatc gatgtcttta ctaaacacga agtaacagca atcgatcctt ctactaagcg
    21841 attaacagtt aaagacctat ccacaaatga agaaataaaa acagattacg ataagttgat
    21901 catctcttct ggtgctagac cagattatcc ggatattccc ggagtttttg aagcagaaaa
    21961 cggctttgtc ctccgtagtg tgacggatgc ggatcgaatc aaatcgttcc ttgaagaaaa
    22021 aaatccacaa catgtcgtca ttcttggtgc aggtgttatg ggtctggaat tagctgagaa
    22081 tttcaagcat cgcggcttag acgtgacttt aatcgatcaa ttgccacaag tcgctttccc
    22141 ttatgatcca gaaattgcta atttagttta tgacaaattg ctgaaagaag gattagccgt
    22201 tcatttagaa acaagagtta ctgagatccg tgataaaggt cgagaaatag tattatcaga
    22261 tggctccgtc ctttctgctg atatgctaat ttttgctgtt ggtgtttctc cgaagaatga
    22321 agtggtgaaa gcaaccggca tacaattatc agatacaggt cagatcattg ttgatgacca
    22381 gttacaaacc aatctgccgg acatctatgc gattggcgat attatcgaaa cgactagtgt
    22441 agtgactggt cagccgatcc aaagtatgct ttccagtgcg gccaatcgtc aaggacatat
    22501 gctggcagat attttaaatg gtacgcctat gcgctatcgc ggatatattg gtgcaggtgt
    22561 cgcaaaaatc tttgatcata cagcaagtta tgcgggaatg acagaacatg aattaaaagc
    22621 atcaggcata acaaattata aaactgtttt tatcactccc tttgaccatg cctatttcta
    22681 tccagaagct acaagattaa atctaaagct gatttttgat gcagatagcg gtcgtatttt
    22741 aggtggacaa gcatttggag aaaaaggtgt cgataaacgg atgggagaac tttctgtagc
    22801 aatcaccgga aacttgacag tctttgattt gcctgatttg gagttgcctt actctccacc
    22861 gtattctact acccgtgacc cgttgaatat agctggttat gtcgcaatca atcaaatgac
    22921 gaatatcgta gaaacgatca aagcaagtga tatacccgaa aacgatttga aagaagcgtt
    22981 ctttttagat atacgtgaac ctaataaagc accttctggc agtatctcgg caacaaaaaa
    23041 tattccaatg aatgagttac gagatcgaat caatgaaatc ccaaaagata aaaaagttta
    23101 cattactttc agaagaggat tgaataatta tacttctgcc cgaatcttgg caggtttggg
    23161 tatcaaagcg attttgattg aagaataaaa aaacgaccgc ggtgggtagc cgcggtctag
    23221 gagttatttt tacttgagga gtaaaaatga aaaagtatat agggttgttg gttggtatgt
    23281 atatagaata gaagataaat gtgaagaaat tgtgcattat ttcttcacat ttattaggtt
    23341 atagtttaag aaagtttaaa cattgcgcaa tttaattatt ttagctgttt cttttcataa
    23401 aaaaacatgt tgtgactctg agacaaatca tagtccatag tgatgtctct agagtaacta
    23461 cgcctaatat tacgaggcat catattaatc tatcagcact agtacctaaa ctagcatccc
    23521 tttcgaatat tttttcttat ataataaagt ttgctttcac tcctctaatc tcaccaaatc
    23581 gactggcttg cgttgtgtga tactaggaac tgattggttt agaacgactt ttctattgta
    23641 atcatatttt tcgccatcct cgttgtcttc taatccttca atgaatgatc cctaatgtgt
    23701 gtattaaata atttaatttt tttgttccta tttatttaa
//
LOCUS       DAXLPC010000037        23327 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.037, whole genome shotgun sequence.
ACCESSION   DAXLPC010000037 DAXLPC010000000
VERSION     DAXLPC010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23327
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.037"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..2132)
                     /locus_tag="ACF3UE_001428"
     CDS             complement(<1..2132)
                     /locus_tag="ACF3UE_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD3634846.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQTADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFEPVPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNN
                     NNGSNNSNNNNNNSNNGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPN
                     TANQSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFEHLGKPYVWGAKGPN
                     TFDCSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVG
                     IYIGNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPATSGSLTGSSILDGLDGS
                     FHFSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLF
                     GIKGSYNGSSVTFNTHEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDF
                     YKPTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEA
                     NAEILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQ
                     IPETTTRTVKAATVPVLTLLSLDKSFWL"
     gene            complement(2489..3862)
                     /locus_tag="ACF3UE_001429"
     CDS             complement(2489..3862)
                     /locus_tag="ACF3UE_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3634847.1"
                     /translation="METTMNPEQMVLYEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRDNMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(3862..4257)
                     /gene="rbsD"
                     /locus_tag="ACF3UE_001430"
     CDS             complement(3862..4257)
                     /gene="rbsD"
                     /locus_tag="ACF3UE_001430"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFD3634848.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(4285..5202)
                     /gene="rbsK"
                     /locus_tag="ACF3UE_001431"
     CDS             complement(4285..5202)
                     /gene="rbsK"
                     /locus_tag="ACF3UE_001431"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFD3634849.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(5311..6324)
                     /locus_tag="ACF3UE_001432"
     CDS             complement(5311..6324)
                     /locus_tag="ACF3UE_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFD3634850.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQISHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEESGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(6405..7004)
                     /locus_tag="ACF3UE_001433"
     CDS             complement(6405..7004)
                     /locus_tag="ACF3UE_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFD3634851.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKGIVNNGTLSPHTAQSILSNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTNN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHVVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            7189..7890
                     /locus_tag="ACF3UE_001434"
     CDS             7189..7890
                     /locus_tag="ACF3UE_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634852.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            7900..10611
                     /locus_tag="ACF3UE_001435"
     CDS             7900..10611
                     /locus_tag="ACF3UE_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFD3634853.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNAKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKAAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            11132..12760
                     /gene="treC"
                     /locus_tag="ACF3UE_001436"
     CDS             11132..12760
                     /gene="treC"
                     /locus_tag="ACF3UE_001436"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFD3634854.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12820..14001)
                     /locus_tag="ACF3UE_001437"
     CDS             complement(12820..14001)
                     /locus_tag="ACF3UE_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3634855.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSVW
                     LVPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYQNSSFSEEDYF
                     K"
     gene            14253..15776
                     /locus_tag="ACF3UE_001438"
     CDS             14253..15776
                     /locus_tag="ACF3UE_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFD3634856.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVASI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFITQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYIEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEALLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(15845..16573)
                     /locus_tag="ACF3UE_001439"
     CDS             complement(15845..16573)
                     /locus_tag="ACF3UE_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFD3634857.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(16586..17866)
                     /locus_tag="ACF3UE_001440"
     CDS             complement(16586..17866)
                     /locus_tag="ACF3UE_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFD3634858.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIALSAFLSALLAFCFKKTLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLVVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(18007..18609)
                     /locus_tag="ACF3UE_001441"
     CDS             complement(18007..18609)
                     /locus_tag="ACF3UE_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFD3634859.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            18854..19060
                     /locus_tag="ACF3UE_001442"
     CDS             18854..19060
                     /locus_tag="ACF3UE_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634860.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            19372..20091
                     /locus_tag="ACF3UE_001443"
     CDS             19372..20091
                     /locus_tag="ACF3UE_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFD3634861.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(20172..20855)
                     /locus_tag="ACF3UE_001444"
     CDS             complement(20172..20855)
                     /locus_tag="ACF3UE_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFD3634862.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            21101..23287
                     /locus_tag="ACF3UE_001445"
     CDS             21101..23287
                     /locus_tag="ACF3UE_001445"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFD3634863.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         7769 a         4210 c         4579 g         6769 t
ORIGIN      
        1 tcaagccaga atgatttgtc taaacttaac aaggttagta caggaacagt tgcagcttta
       61 actgtacgag tagttgtttc tggtatctgt cttgccgtaa aattgttcca caaatcccag
      121 attgaagcga cacggaagat ggaagaagcg ttgttgacgc gttttatcgt tgaaaattct
      181 aatcctgtga ttggcacgcc atctgttgtc catttgattg gcacatcgaa tcgcttagac
      241 atattgagga tttcggcgtt tgcttcttca gttgttgctg cttctttttt cggttcatca
      301 tattttgtca ggtcgtacgc ttcgatgatc gcgttcaatt tttgtgaata ttggcgatct
      361 gtagcataac gtccttccaa atatttggtt gcttctttgt agtcttttgt ttccgacttc
      421 caagttggtt tgtagaaatc aggattgcca gtcagtccat ttttgatcaa gtcggcatag
      481 tcttccaaac tttccttgta agaaggatat ttacggaatt gtgcgcggat ttggtagctt
      541 tgtccggaac tatcttgttc atgtgtattg aaggtcacgc tgcttccatt atatgatcct
      601 ttgataccaa aaaggttatg atttggttcg cttgataata agctgtttcc agatccactt
      661 tcaaggatag cttgagccat catgactgat gcgtagattc cttctttttg cccgatttcc
      721 tgtgcatcat ctgcaatctt tttcaagaac tgatcagttg tttggttttg actgaaatgg
      781 aacgagccat ctaatccatc taaaatagat gaaccagtta gcgagcctga agtagcaggt
      841 aaacctgcta agtttactcg gacagcaaaa tcaggcgtga aatctgaaat agaagttact
      901 cgaactttat ctcctggttg gggcgcatgg ataaattgtc cgttcccaat atagatacct
      961 acatggtgag taacaccgga agaaggtccc cagaagacga gatcgccagg ttgggcctga
     1021 cttactggaa tctgcgtacc tgcatattgc tgttcgcctg tccagccacc gatataatga
     1081 ccggttgctt tcatatatac gtaataagtc aaaccagaac agtcaaaagt atttggacct
     1141 ttggctcccc atacatatgg ttttccaaga tgctcgaatg cttctcgaac gattgcttgt
     1201 tggacattcg ttgtatttgt aggcaataca gcatcaattg gtgattttac aacaaaatca
     1261 gaagaagcag aagatggatt ctctataccg ctttgatttg ctgtatttgg acgagatgaa
     1321 gcattgttcg ttccgccatt cgatgaacca ttgtttggat ggtttggttc tctctgagta
     1381 tttccattgt tattcgatcc agatgggttt gtttgattcg aagaattccc gttgttcgaa
     1441 ttattgttat tattgtttga attatttgaa ccattattat tgttgttatt gttgttatta
     1501 cccacatctg gtttgtttgg cgtttccgga tctggtgtac tagggacttc ttcactagga
     1561 tcagttggtt tctctgttga agtatccggt acaggttcaa attctgcagt aatagataaa
     1621 ttgttcgtac ctactgtaaa ggtctttgca tcataattta cttctttggc accattaaca
     1681 gcgactgaag caatttgttc accttcagct ggcgtaatag tgtaagttac cttcgtttcc
     1741 gctaataaac cttctaccgt tccactttcc gtaatatcca aaggttgctg ttcaggggaa
     1801 tccgctgtcg aagcagtcag ttggatctta ccaatcaaag aaggagcaat tgtaagggaa
     1861 tatgtctcgg ctggcttttc attttctgat ggatcagccg gatcaatttc agttggctcg
     1921 gtcgatcctg ttgttgagtt agttgttcca gttgggtctt ctgtaaaaga atccgttgtt
     1981 tcactagtag ctgagctgga tgtagtcgta tctgttgtga ctgtttgatc tgctgtttga
     2041 ttatctacgg caaatacggt attggtcgac aaaacggacg gagcaatcag ccaagtagca
     2101 gctagcaaac gtatcgtttt tttatttttc ataataaact agtccttttc ctttcattga
     2161 ttttctgtct tattcagcat tcattagaca ttttttggaa cagataatcg tgtcgaaaag
     2221 ctttttcttt tcataaatct gtctgtgtat tctaaataaa acaatttgta aataagcaac
     2281 gagcattcat tcgtttttct ttgacgttca ttttattgca tagaccacct ttgtttgggg
     2341 ataaacaagt ggggataaaa atggttatgc atatgtaaat tataccaaag tttggaaagt
     2401 atcacaaaaa tttataaaaa taatgatcct aaaaagaaaa agactgaaat atgtgataaa
     2461 catctcatac ttcagtcttt ttcattaact attcataaga cattaggtct tcatcaaacc
     2521 cgctaacgag agtagtaatc attgctacga ctagactaac agccagtcct gctaagtacc
     2581 agaaaaaagt accggaaatg aatgcaggca atgtggtcag actaccaaat acaaaagcga
     2641 tcgctttcac ttgggcaaat cccattacag ctccaccagc agctgcacca atgcaagcag
     2701 caacaaatgg ttttttcaat gggatcgcaa ttccgtaaac agttggttcg gtcactcccg
     2761 caagtaaaat cgaagcaaaa gcagaaccgg agatcgaacg agtttttgaa cgtttacttc
     2821 gtagaaatac acctaaagct gcaccagcca ttccaaaatt ggctgctcct gtcaacggaa
     2881 cgattcggtc gaacccataa gcagagatat tactgatcat gacagggttt acagcccatt
     2941 ggataccaaa tattaccaaa atattccaac caccagcgat gattgcgccg ctgatcggtc
     3001 cgttaatatc catcatccaa gtaattgcgg cagctaaacc ttcgccaagg taaacacccg
     3061 caggcccgaa taccattaac gtcaaaggaa ccgtgataac taatgaaagt aaaggtacaa
     3121 atactaattg catattatcg cgaatatatt ttttgaggaa tttttcaaca aaagaataaa
     3181 agaaaatacc taaaatcgcc ggcatgacag tagacgtata ctgcatcagt actacaggaa
     3241 tccccagaaa atcagtagct gctttgccac tgtctgaaag taaagaggtc agattcggtt
     3301 caatcagtgc tgcagcaatg acagccgcaa tatatccatt cactttaaac gttttggcgg
     3361 cagaaaaagc aagaaagatt ggcagaaaat aaaagacggc attcgacgca gcagacaaaa
     3421 tatgataagt tccgcttgtt tcactaagcc agccaatcgt agtcgctaaa acaaccagac
     3481 cttttaatat accagaaccg gcaaacagcg gaatgatcgg cgtaaagatt tccgatatca
     3541 aaccaaatag tttttcgatc ggatttagct tttctttcgg agctgaatga tcgatttgac
     3601 gcgtcaattc cttgtaagca ggagccaatc cctgatccat gattatttct gcatatctat
     3661 cgagtaaaat gaaatactta atggaaggga tttgctgttt taatttttct gcattggcta
     3721 ctggctgttt tttcaatttg atacgaagcc gagtcgcaca tggaaggaca gaatcaatat
     3781 tgtcttttcc tcccaactgt tcaatcagca tatgaatctg ctcgtacagt accatctgtt
     3841 caggattcat tgtcgtttcc attagaagac cactccactc actaatataa tattggcgta
     3901 aggtgtcatt tcgcctgtac gaataaatgc atgacagtta ttcaactctt ttttcatttc
     3961 ttcatgtggg ataaagctaa tcggtgtatc tggtaacaat aatttgattt tttccaatat
     4021 ttccggattc attgtcttta tttcttccgc caattcaatc gattgtacct caagttcttc
     4081 taaaacgttt tctaaaacag ataaaaagct tggaagaccg tttgagacag ccaaatctat
     4141 tttttcagta ccaaagggga caggcatgcc tgcatccccg atacttaatt tatcaaagtg
     4201 ccccatttgt gcgattactc gtgaaatatc tgaattgatt acttttcctt ttttcatgtt
     4261 tgtttcttcc tctcattgtt aattttagac tgctgattgt tctaaagctt cgcggtaagg
     4321 gatagaaggt tgcgcaccat aagactgcac agcaacagaa gaggctagat ttccataaag
     4381 gatcgcttct ttcaagttac taaggtctgg ctgaagtgtg ctgcttaatg cgccaataaa
     4441 tgtatcacct gcggctgttg tgtcaacggc atccacttta aaagcaggga cgataccgtg
     4501 ttctttttct gtatgataga aagcgccggc actgcctagt gtaatgatta ctgttccaat
     4561 acctaattca tggagttttt cggctgctgc gaccaaactg ttatgatctg tcactctgat
     4621 tcctgtaatg atttctgttt ctgtttcatt tggtataatg atatctgtct tttcaagtag
     4681 ttcagtagga atcgtttcac gagctggtgc aggattcagg atcgttgttt ttcctgcgtc
     4741 ttttgcaata gaaaaagcta ggatcgtcgc atctaagcta ctttcaaact gagcaataat
     4801 aaagtcactg tttgtaatca gttgcttgtt ttttaggact tcttgttcat ggaaagcatt
     4861 atttgcccct gcatggatca agatactatt ttctcctgct gcgtctacca taatcattgc
     4921 ttgtccggtt gtggcgcctt ggatttcagc tatcccagat gtatcgatgt tttcttttgt
     4981 cagtagatct aataactgtt gtccttcgct gtcagcccca acgcctccaa taaaagatgt
     5041 ccgtgcgcct gaacgtttgg ctgccactgc ttggttggcg cctttacctc cgccagcgtg
     5101 aaaaatctca tgcgcatgca tcgtttcgcc tggcttgggc atgttggtta aacgaagggt
     5161 agtgtccata ttaatacttc caattactgt aaccgtgttc attttacaaa cctccaacta
     5221 tctcatttat tttgatggga aaaattattt tttaaaacgt tttagtaaaa cgttttaata
     5281 gttcgataaa aatatagcac accttgaaag ctatttcaag ggtgcagttg aaaatctttt
     5341 ttctaatcgt acaggtaatc ttttttcttc ccattctttt tctgggaatt ggatccgatc
     5401 taacaataat ttggcagatg tttgtcccaa ttcgaagatc ggttgtgcga tcgttgtcag
     5461 tttcggcttg atatactcgc acatatctat attatcatag ccaataatgc tgtagtcttc
     5521 agggatgctt tttccagatt cctctaatcc gcgatataat ccaaaagcta attcatcatt
     5581 taaagcaaac acaccagttg cagcagaatc aagaagttct gctgtgattt ggtagccacc
     5641 ttgttttgag aactgtgtag gtaagaggat cagttggtcg tgagagattt ggtaaacatc
     5701 aagagcagat ttaaacccct caatccgagc gtggacattt tccggcggat tttcaggata
     5761 gacaagggcg atcgtttgat gacctagact aagcaagtgc atgcccgcta ggtaaccacc
     5821 gcgaaaatcg tctgttcgta cggcatcact aaatccttca gattttttct gatccaaaac
     5881 aatgaagggc cggccttgtt ttttcaaatt ttcgttgatt gcatctgtag agacagcaga
     5941 agtcgcgata atgaatccat ccacacctcg acgtgtgagc tcggctagat attcgatttc
     6001 tttttgatga tcagaatcag cattacataa tatcgtgacg aaattctgct tatacaagat
     6061 atcctcaatt cctcgcatca gtgtactgaa gaatggattc gtgatatcag gaacgagtac
     6121 accaattgtt ttcgtttcct tggtaatcat ttgtctagca aaatagtcag gctgatagcc
     6181 taattcttct ttggcagcta aaactttctg aacagttttc ggactgaatt tctccgtatt
     6241 tccatttaat atcaaggaga cagttgtgat tgaaacgccg gaaagtttag cgacttcttt
     6301 gattgtgatc ttttttttca ccatgttcat actcctatct aaatcctgtg gttattttcc
     6361 catgaaatca aaaagaagta aatgaaaatc acgtgtgcca gtacttattt gctttgttgg
     6421 atagcttcga ttatttgttt cgttgagcgt actcgtgcag ttttcggaaa tatctttttt
     6481 atgaacaatt gatgggattc tttgtcacga tcactgcaag catcttcagc aagtacgaca
     6541 tgatacccat gttggaaggc atctaatgca gtagcatata caccgtttgt tgtcgctaca
     6601 ccgcttaaaa tgatagtttc gattccacgc cggcgaagtt gaagatcaag agaagtacca
     6661 aaaaaggcac ttggattgta ttttgtgata gtcaacatat tgtttgtatc tttcaaggaa
     6721 tccttcaaca acaagtcagt gaattctgga ggtacagaag cagtcattcc acccatatca
     6781 gtttgttgac tcaaataagg gaaagtggag atgtctacgt tcactaaaac tttcaaggca
     6841 gcggtacgtt tcaatgttct tactaacaaa tcattgtttg acagaataga ttgtgcagtg
     6901 tgtggagaga gtgtaccgtt atttacgatc cctttttgca tgtcgatcgc gacaaaagca
     6961 gtttttgata aatcaaaaat catattttcc tttaaatcat tcatgatgtt ccttctttca
     7021 aataacaatg ttttttatgt aagtaaatca taaatcgttt atttgtcaac taaataaagg
     7081 attcctttct ttagtctaga gaaattcagt ggtaaaataa ataagtgtga gaaaacgcat
     7141 tctatgcata gatatagcga gaaatatcgt gaaaatggag gaatcagagt gaagtatgtc
     7201 gaagtaaaaa atgaatacaa acgatacaaa atgggagaaa cgaccattac agcaaatgac
     7261 gatatttctt tttcaattga aaaaggcgaa ttagtgatta tacttggtcc aagtggagca
     7321 ggaaagtcaa cgattcttaa tattttaggt gggatggata cacctgatga aggtcagatc
     7381 attattgatg acacagatat tgcgcaattt tcagataaac agcttactgc ttaccgacga
     7441 acagatgtag ggttcgtttt ccaattctac aatctcgttc ctaatctaac agcaaaagaa
     7501 aatgtggaat tggcaacgga agtttctcct gatgcgcttg atcctgtaga ggtattgagg
     7561 caagtgggcc tagctcatcg attgaataac tttccgtccc aattatcagg aggcgaacag
     7621 cagagggttt caattgctcg tgcactagct aaaaatccca aacttctttt atgtgatgaa
     7681 ccgacaggcg cgctggattt tgaaacgggc aagcaagtat tgaaattatt gcaaaacgct
     7741 agcagacaac acggcaatac cgttttgatc attacacata attctgcttt agcgcccatc
     7801 gctgatagag tcattcacat taatgatgct aaagtaaggt ctgttgaatt aaatgatcat
     7861 ccttcatcca ttgatgagat tgtatggtag ggggatttta tgaaaacaag aacatatctt
     7921 aaagcaggtt ttcgcgaaat tcggcaatct aaaggacgat tcattgcaat catccttatt
     7981 gtcatgctag gaacactttt atttgtaggt gtcaaaactg ctggacctgt catgcaaaaa
     8041 acgatggatc actatgttgg tacagcagga ctttctgatt tgcaaatcgt ttctactggt
     8101 ggcttgacac aaaaagatat tgctcaagca gaaaagatcc cagatgcaaa agtagaaaca
     8161 ggaaaacaga tctattattc caatactggc aaaaacgaag tgattcaaat attttcttat
     8221 aacaaaaata acaagcagaa caagctacaa ttaactgatg gaaaactccc ggaaaaacca
     8281 aaccagcttg tattggatga aaaagcggaa gatgaagggt ataaaatcgg tgatatttat
     8341 cagattgatt cagatgaatt gaaagaaaaa gagtatacca tcacgggctt tgtccgttct
     8401 ccattgttca tcaacaattt ggagagagga tacgcgaacg tcggaaatgg tagcgtcgat
     8461 tattttgtct atttacctga atccgttttt aaaacagata tttattctgt cttatatctt
     8521 gattttacaa acgcaaagaa tttgaatacg tacagcaaag cttacaaaga taaaatggag
     8581 caaaatcaag aaaaggcaga aaagtattta caagatcgac ccgaagaacg cttagaagag
     8641 ctgaaaaaat cggccaacga agaattagaa ccggcacagc aaaaaatagc ggatggcaaa
     8701 gcacaaacaa cgcaagcaag aacacggtta gaagatgcta aaaaacagtt agcgcaacag
     8761 tcagcaacta tccagcagct tcctgaagcg caacgaacaa tcgctgttca aacattatct
     8821 caacaagaag ctcaacttgc tgaacaagaa aggcaattag ttgagaaaga acgtgaactg
     8881 gcctctgcag aggaagaatt gaatcgaaat gcagaaaaaa ttgaaaattt aactaaacca
     8941 tcatacctat acaatgaacg ttcagaaaat gtcggttttc aagaatttgg tgatctgtct
     9001 gatcgtatcg ctgcgattgc caatgttttt cctgttttct ttttctttat tgctgcattg
     9061 atcaccttta cgacaatgac acgtatggta gaagaaaacc gcagggaaat cgggacatta
     9121 aaggcgttag gttatacgaa agttgaaatc gcaaaaaaat atgcaatcta tgcaagtcta
     9181 gcctcaggga taggcattgt tttaggaacg atattaggaa cgaatctttt gccaaggatc
     9241 atttttgagc tgtctaacga gcggtatgat attgggagtg cgcttatttt ttatgactgg
     9301 ccgccgattt tacaagcagc tgccgcattc ttcattgccg catttggcgc tgcaatgatc
     9361 gttttattca aagatttaag agaacggcct gctgcattgc ttcaaccgaa agcaccgaag
     9421 ccagggaaac gcatttttct tgaatacatc actccgctgt ggtcacgcct tagctttaat
     9481 caaaaaatca gttaccgaaa tctcttccga tataagtcaa gaatgcttat ggcgattatc
     9541 ggaattgctg gatgtgccgg gctgatggtt gcaggcgtgg gattgaaaga ttctctaagt
     9601 tctgtctcag ccaaacaatt tggaccgatc attgactatc aagcaatcgt tacattggat
     9661 tcatccacgg aagatagtcg tcaaaaagca gcggatatgc tgcagaagca agaaaaagta
     9721 aatgagatcc tagctattca tactcaaacc gtagaattga gaaaaaaagg acatgcttcg
     9781 caaagtctga cagtgatcgt accaagtaaa acagctgatt tggatcgttt tatccattta
     9841 actgatcttg aagagaaccc acgctccttg cctaaaacag gaatcgctat tacgcaaaaa
     9901 gcagcagaac tatttgactt atctacagga gatcatattt cgctttatga tgaagatcaa
     9961 aaagaatgga aagtcgaagt aaaagaaatc gtgaaaaact atctaggtag ctttatttat
    10021 atgtcccctg aatattatgc ttcagttact gatcaatcga tgatggataa tgcatttttg
    10081 ctgcgtacag ataagatgac aacaaaagaa gaagaaatgc tttccgagaa actgcttgcc
    10141 acagacgctg tgacaaatac gtctttcatg tccaaacaaa tcgaaacgca agaagaatca
    10201 atggcgaact tagactcggt tgtcttaatc tttgtcgtat tatcaggact gctggctttt
    10261 atcgtcttgt ataatctaac taatatcaat atttccgagc gtgtacgcga attatctaca
    10321 ataaaagtcc ttggattttt tgataaagaa gtcacgatgt acattgttcg agaaaatatc
    10381 atctttactc ttttaggaat catcggagga tttggtgtag gatatatatt gactgacttc
    10441 atcttgcaac aagcgtctat ggagaatgtc atctttccat tagtgatcac atggtgggct
    10501 tatgtcttat cagcaggatt aactatcgta ttcacggtta ttgtgatgat cgttacccat
    10561 ttcaaattaa agcatatcga tatgattgat gcgttgaaat cgaatgaata aaaacagagg
    10621 ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc aaacaaaaat agcttctcat
    10681 atttttcgtt tgattgggcg tattaccgca gatgcaagct tttaaacacc gcttaaggaa
    10741 gaggttgtga aatcagcgtt ttgagctaat aacgagggtc agctgctaat tgaacaccgt
    10801 gaatcagagg ttgtgaaaaa gctgtcctgc atcgagcaaa aagaatactc aaataaaatt
    10861 agctcctcat gttttacatt tgagaagact gattgccgta gataaaagct tttgagcacc
    10921 atttatagaa gaaacaagaa tattttgcta ttttaaacaa gaggatagac aaatacatgt
    10981 ctgatctctt gttttttatt gggcaacaga cctcttagaa tgtataaaga taaattttac
    11041 aaacgctttc ggttcagtta taataataaa tgataacttg tatatataag ttttggtagg
    11101 taataaatca gttgaatgga ggtaaatatc catgacattt aaagacaaag tcatttacca
    11161 aatctatccc aaatcttaca aagacagtaa tggtgatgga attggagatt taaaaggaat
    11221 caaagaaaaa ctcccgtatc tgaatgatct aggcatcgac atgatttggc taaaccctat
    11281 ttatccaagc cctcaaaaag acaacggtta tgatatctct gattacacag ccatcgatcc
    11341 tatctttggt acgatggagg aattcgaaca gctaatagcc gaagcaaaga aataccggat
    11401 agaaatcatg ctcgatatgg tgctgaatca cgtttcgaca gaacatgaat ggttcaaaaa
    11461 agcactagca ggggaccagc attatcagga cttcttcatt ttaagagaag agccaacgga
    11521 ttgggtatca aaatttggtg gaagtgcttg gtcgccattt ggagatacgg ggaaatatta
    11581 tttgcactta tatgatcgga cacaagctga cttgaactgg cggaaccaag cagtaagaga
    11641 ggaactattc aaagttgttc gtttttggat ggaaaaaggg gtaaaaggat tccgtttcga
    11701 tgttatcaat gttatcggta aagacgaaca attgaaaaat aataaagaaa atgatggcaa
    11761 acctgaatat acggacaaac caatcaccca tacgtatcta aaagaattga accaagcaac
    11821 gtttgggacg gattccacta tcatcacagt cggtgaaatg agctctacga cgatcgaaaa
    11881 ttgtatcttg tatacagaac ctagtagaga agaattatca atggtcttta atttccatca
    11941 tttgaaagtc gattatgaaa atgggaataa atggtctact cctccatttg attttgcaga
    12001 attaaagcga ctatttcata catggggaga aaagatgagt gagggtaacg gctggaatgc
    12061 tctatttttt aataatcatg atcagccacg tgcgctcaat cgatttgtag ctatcgatca
    12121 gtatcgaaaa caaggagcag agatgctagc aaccatgatc catttgaacc gtgggacgcc
    12181 ctatatttat atgggagaag aaatcggcat gatcgaccca gactattcat cgatttccga
    12241 ctatattgac gtagaaagtt tgaatgctta taagttactc cttgaacaag gattcacaga
    12301 aaaagaagcg tttcgtcgga tcaaagcaaa atctcgcgat aactctcgaa cacccatgca
    12361 atggtcagac acagaacaag caggatttac tacagggaaa ccttggttaa aagttggagg
    12421 caagctagaa gagattaatg tagaaaaaga actatcttct gaagattcta ttttgtccta
    12481 ttacaagaaa ttgattcggc tgagaaaaac atatccaatc gttgcacaag gagattatca
    12541 tgcttatgaa gcaaatcatc cggaagttta tggctttctt cgccaatttg aaggacagca
    12601 gctgcttgta ttaacaaatt tctatgataa agatacaagg atcgccatcc cagaaggatt
    12661 cacagaagcc aatattctta tcgataatta ttccgatact gttcttcatc aaagtctgga
    12721 gctaaaacca taccaggcaa ttgctttgct gaaaaattaa aacaaaaaca caaaacgtcg
    12781 ttcctacgag ctattctcgt aagatcgacg ttttgtgttt tatttaaaat aatcttcttc
    12841 agaaaatgaa gagttttgat actctccttt atcgccataa aatttattgt agcgttgttt
    12901 gaatttacgg aaaataaaag taacgagtaa tttgactaac gtatagatag gaataccaaa
    12961 aataacgccc acaattccca ttagatcacc catgacaagt aaaacgatta agatcgtaat
    13021 cggatggatc tgtaaacgat cacccattac tcgaggaatc accaagtcac cgtggagaag
    13081 ttgtacggca aaccagacaa tgacaaattt gacagccata aaagtagagt cttggaatgc
    13141 aatgatcaaa cctggaaaga aggcgataaa cggcccaata tatggaatga tacataacaa
    13201 cccagcagaa atagctaaaa cactagcaaa ttctaatccg atcagtaaga aacaaaccca
    13261 gtagactgct ccaaggataa atgaagcaat gatttgcccc tttagaaatg aacccaattg
    13321 ttgattagca atctttgtca aatttttaaa atctgtacga aatgctggtg ggacaatcgc
    13381 taaaactgac tgataaaatt tttgaggatc tctcaaaagg aaaaaagcga caattggacc
    13441 agtaaataaa gtaataaaaa tagctgtaac agttgaaaaa atgttgctga tccgttgtgc
    13501 gccactttcc caataatttc caataaatcc agctatatca gacgtcacgt cgtcaataga
    13561 agcgaaaaat tgattaaatg aatcggcaaa aggtgttttc tccaaaaatt gtcggagact
    13621 ctcttgaaaa tcttgaaaca aatctggcaa actactgatc aatgtctttg cctgttcttc
    13681 aagaaaagga acaagccata cgcttccaag ccccaataaa aataaaataa tcacataaac
    13741 gataatgact gacaagttcc tcgaaaggtg cttgctcaaa cgtttgatga ctggttccaa
    13801 aagataatac aagatcagtg caaacaataa tgggggcaag atagtagcga taatgattcc
    13861 gacaggcttg aatataaacg agatctgatg gaaaaaataa atgatcagcg caagtaagat
    13921 aactattcct aaaacatagt aagaggtttt tcctcctaaa aagcggatca aacgattcgt
    13981 tgtatctgtt tcttttttca atctttttcc tcctttatct ataacttcat tatagacaaa
    14041 agcgggtata aaaggaaaat gatagaggtt gattgcaaaa atatcgtcaa tcattcacat
    14101 aaactttctc atcaattaaa ataagaaaac gcttgacagt tattttaacc atatgataaa
    14161 ttaaatcctg ttgctaaaac gtaactatta cggtttacaa aaggcgaatc ggaacattca
    14221 aatgaaagaa gatgagaaga ggagtgtcat aaatgaaacg attgataggt atattggcca
    14281 tgctggtttt agcaggtatg ttaactgctt gcggggcaag tgggaaagcc gaggacagta
    14341 aagaaaaatt gagcgtgatg acgacctttt atcccatgta tgattttaca aaagcaatcg
    14401 tcggggatga aggagaagta gagttattga ttccagcagg gactgattcc cacgattatg
    14461 aaccttctgc taaagacatg gcaaagatcc aagatacaga tatctttgtt tataatgatg
    14521 aaaacatgga aacatgggtc cccgcaatcc aaaaaacatt acaagaaggc aatgtccata
    14581 cgataaaagc gacagaaggt atgcttttac ttccgggaag tgaagaagga catgatcatg
    14641 accatgaaca cggggaagaa ggccatacac acgagctaga cccacatgta tggctagcac
    14701 caagtttagc aatcaagcag gtagcaagca tacgtgatca gctgattgaa gcttacccag
    14761 aaaaacagga agtatggaca aaaaatgcag cagcctatac cgagaaactt caagcactcc
    14821 atcagcttta tcaagaaacc tttaagcaag caaaacaaag atcttttatc acgcaacatg
    14881 ctgcattcaa ctatctggca ttagaatatg gattgaatca agtatcgatt gctggtcttt
    14941 cttctagtga agaaccgtct gcggcgagaa tcgctgaact gaaacacttt gttaaagaac
    15001 atggaatcaa ctatatttat tttgaagaaa acgccaaaga tagtattgcc agaacgttag
    15061 caaatgaagc aggtgtatct ttagaagtat tgaatccttt ggaaggattg acgaatgaac
    15121 aaatagaaaa tggagaaaac tatctttcta tcatggaagc aaacctcgaa gcgttgaaaa
    15181 aaacgacaga gacagaaaac ccgttagaag atactttgac ccccaaaaaa gaaaagagcg
    15241 tctataacgg ttatttcgaa gacgaggatg tacaagatcg ctctctttca gattgggcag
    15301 gaacttggca aacagtagat acgtatatag aagatgggac atttgatcct gtttttgaat
    15361 ataaagaaaa attgaatcag gataagacag cacaagaata taaagaatat tatacgaagg
    15421 gctatcaaac agatattgct tcaatcaaga tcagtgagaa agagatggca tttacgttta
    15481 aggatggaac aacgaaacgt tcaaattatc gttatgtagg gaaagaaatc ttgacctacg
    15541 aggcaggaaa ccgtggcgta aggtatctat tcgaagcaga agataaggaa agtggcgctt
    15601 ttagatatat tcaattcagt gatcacacga ttgcaccggc tgactccgaa cattttcatt
    15661 tatatgcagg aaatgaaagt caagaagcat tgctgaaaga aatggagaat tggccaacat
    15721 tttatccaga tacaatggat ggacgtgaaa ttgcacagga aatgcttttg cactgatagg
    15781 caaaaaagaa ccgaagggtt tggatcggct ggtcatttag tcggtccaaa ctattcggtt
    15841 ctttttatga aatcaatttc tttaatccac ggatagaggc tgggatggtc tcgccgtttg
    15901 ccaacgtgac ttctctggtt tttttattaa tcgaccgcac attttgtgta ttgataacat
    15961 aggatttatg acaacggata aaattccgat gcattttctc gatttctttg atcttctcat
    16021 agaattgtaa ttgggcatga gtcaaatgga cttccagttt atgtggtgct cctagcgaag
    16081 tagaaaaata ttggatgtct ttgatcggta aaaatttgat ctcatcatta aactctattt
    16141 tgaagatatc tttttggatc tgggacattt gaaaatcttc gaaaattttg ctcaggatat
    16201 gctcgacatt ttcttttaaa tcataaagat cctctttgac gatataatca gtcggttcaa
    16261 tgttgctttt taagattttc atcgacattt ccgtatggga agtcacatag attatttttc
    16321 ctaaaggatc taattcacgg atcaatttac cgatcgctac accatccatt tcactgtctt
    16381 ctagttcgat atctaaaaag taaataccaa aagaagaagt tctgatcttg gctgcattga
    16441 gaagttcttc cggatcagag gtagaaatat ggacataact gtctaagttt tcaatcatga
    16501 ttctattttt gatcaccgtt gataaaactt ctaattgttt tggatcgtct tcacaaatat
    16561 aaatgggaat catatcatta ctcctttatt ttatttgtat ataaatcgtt tgagaaaaac
    16621 gctggttttc aattgatgtt tcaaggaaaa gataaggatt ggtctttgtc aattcatcca
    16681 agataaacaa gccaaggcct tcgttttttg gatttgtttt tgttgagaac cctttttgtt
    16741 tcaactggtt taacggcaat gtatttgttg ttgtattgat cacacgaatc attacggaat
    16801 gattcttctt gagtatggtc aattcgattt ttttcttctt tgcagcacta gctccttcaa
    16861 tcgcattgtc caagataata ccaagcatac gtacaaggtt taccgtatgt ttcgtatcca
    16921 gttcgattgg ctcaggaaaa tgaagctgga cgaccaaccc tttttcctgt gccatcatga
    16981 gttttaatga cagtaaacta cggatctcag gaactttcat attatccaac atacttagat
    17041 tggccggaaa aaggttcatc atctggcgtg taggtaatat cgtttgatca taataagacc
    17101 gtaatccttc taagtcgcct tctgaaatat agctgtgaag agaaaaaagc agattttggt
    17161 aatcatgttt gaattctctc aagtcttgat agtttttttc tagatctttg atataatcct
    17221 gttgcatcct gacttgttgc tctaataact gatcagctaa tttcttatta gagattttcc
    17281 aataataaac caagatgatc aggccaacac acagatatag aatgaaaaaa ctcgtattca
    17341 aagctaagac atcaggtgtt tcaccagaaa aacgggtata aaaaataatg atatagtatg
    17401 taaataatat caatgtcccg atcgtaccga tcatacggcg gtccacagtg tgaaaccaag
    17461 tctctaacgt ttttttaaaa caaaaagcta ataaagcaga taaaaaagcg gataaggcaa
    17521 tgtgaaaata ctgcaatgaa tctcctggtt caataaccga agatttcaaa acaaaaaaat
    17581 cgccgatgct tgttaagtga tctcctaaaa gcgacgtcaa taacccaaaa ggaagggcgt
    17641 aaaccaattg ttgacgcgaa gtcgaaaaga agaaaaaagt aagcatcagc attcctatag
    17701 caattagagc agtaaaaatc cctaaaatcg aatagaccca tccaatcaaa atacaagaaa
    17761 tcagaatgac tcccgcaaac agatatttgt atcggatgtg atggtcaatc aataagatac
    17821 aaattgtgta aatcaaatat tgcaacgcta tggaccataa aaacataaag tacagctccc
    17881 attgattttt accaaattat agcacaatta gcgtattatt tttttaattt ttcagggatt
    17941 ttgaattcag aactcatacc aaagcagcag ccagatacaa aaaagtcaga taagttagtt
    18001 aattgtttaa tgattgtttt tttcatgaaa gattcctcca aaattcatca agtagtttgt
    18061 aataggaagc aacgtagcta tttctaaaac aatcccaagt agcaaatagg tagaaaagta
    18121 agaagctgag aaaaataaag taatgagaga aaaaattaga aacatgctga tcgccttctt
    18181 taataatggg ggacgtttct cgggttcaat gggattgatt gctgtacctc ttgatccata
    18241 gcgaagcagt aacaaaaagc agctgattaa caaaaagacc atcattggga aggagatagt
    18301 caattgcaga tgtttcatca ccaagggaac gccccataaa taaagtagtg tccacagcag
    18361 acaaacgaat tcagagtcgg aatgcaatcc ataagcatat ctgcggatgc agatataaga
    18421 aagaaaggtg attcctgttt ccgcccatga gcctgtcacc agagaaaaga ctagaacgac
    18481 cgctagtttt ccaagattat tcaataaaac ttctaaggca aattttactt ggacatacac
    18541 catatcttct tccgatttgt ctccgctgaa taaggcttct aataatttgt tcacaacttt
    18601 atctttcatc tcatacgtac ctccaccaca aattttatgc taaaaaaaat aaaaaacgtc
    18661 ttttgtttca taaaaagtgg ttttgacatc aaaaccgtca tgatttccta aaaaaatctt
    18721 cgttttccaa gaaccttacc aaaaaaagtg acagttttga tacgaaaagt actttttatg
    18781 acaagtttgt gctttttcga gtgatttatg ttaaaaaatt actgacctta taaaaggtga
    18841 tggagggatt cttatggaaa atgaacaatt gtttgaagtc ggcgaaacat atgcatttaa
    18901 atctgattta tttgaatcac caataaaagg aaaaatagaa aaaatctatg aaaatagtgt
    18961 gatgatacgt gtcatgaaat gcgcagtaga agacaatgat accgctcata atctgcactg
    19021 gcagttagtt gtacgcaaat caagtacaat agaagaataa aaacagataa aatgttgaga
    19081 gcataaagag gttgtgagtc tcccgtttag ctctgagtta caaggaataa tgttaaaaaa
    19141 cagcttttca tgttttatga atattgcctt gtgaccgagg tgttggcagg agaatactgt
    19201 ttatttgaaa aaagggctgc gacaagactt ttgtcacagc ctttattttc atgaatagga
    19261 gttacttttg gctactttta gagaagtagc atttaaggag cagataaagt caaggctttt
    19321 atttctataa atgaagtagt aaaatgaaga acagatttta ttacaggaag gatgccgata
    19381 attgtgatca ttgttgcagg aacgatcggt gcagggaaaa gcacactgac tgaaatgctt
    19441 gcccaagatt tagaaacaaa acctttttat gagaacgtgg aagataatga agtattgccg
    19501 ctattttatt ctaatccaga aaagtatact tttttattac agattttctt tttgaacaaa
    19561 cgctttttgg caatcaaaga tgctttcagc catgatgaca acgtactaga ccgctccatc
    19621 tacgaagata gtatgctgtt tcatttgaat gcagatttag ggcgtgtttc tgaagtagaa
    19681 gtaaagcagt atgaaggtct tttagaaacg atgctgaagg agttagaaga aatttcgcca
    19741 caaaagaaac cagatctact ggtttatatt cgtgtatcct ttgaaactat gttagcgaga
    19801 atcaaaaaaa gaggccggga atatgaacag ctagaacaag atcctgaact ctattcctac
    19861 tataaagaac tcaatcgacg atacgaagag tggtatgaac agtttgatat atgtcccaaa
    19921 atagtgatcg atggggacaa atatgatttc gtagccgatc cggcatgtgg agaacaaatc
    19981 gtacaagaaa tcaagatgcg ggcaaagaaa atgacagaag aggcagatgc ccagtcgatc
    20041 cgctacacta caaataaccc gaaagcaaag ggaatcttta caactaaata atataaaaac
    20101 taagcaaatt gctcactcgc agatatttct ctgtgagcag catcttgctt agtttttttg
    20161 attcattgag atcaaatagt gaaccgattc gtatgataaa attgccataa atgaaatgtc
    20221 tgagtgaggg ccatgatcaa aaataaaatg gaaacgatca aaatcgaatg ggcgccaaac
    20281 agatgatgac agaaaacaag gacaatagct cctgcgataa aggcaagaac gacacttaga
    20341 tagtggaaaa atcgatcaaa atctgctttt tctttagaaa tacaataatc atataagttc
    20401 gttgctaccc cttttaaatt tccagttgta aataaattag tgtaggcacg cccgttgatt
    20461 ttatcaaaag ctacccactg gatcgatgca gtaaaagcaa tcaaaatcgt tactaatgcg
    20521 ggatgctcat ggacgggtgt caaactaaca aagaaaaaaa tcactgcttc ataatataga
    20581 acaaacaagc gccagaaatg tttttctttt tttctaaaat aatcaatcag atactttgtt
    20641 agaagaatcc ctaagaaaaa gaaaagggta gacaatactt ttttaccaac acttagccat
    20701 tctccgtcaa atgcttggat gatcgataga atgatattgc cagtttgagc agaggcaaaa
    20761 gcaccatatt ggatataagt ataactgtcc atggctcctc cgataaatgt cagcaaaagt
    20821 cctattgtac gcccctcgtg aaaggaagtc tgcatttttt tcatcacctt ttatgaatat
    20881 ttttgtcttc cttatcttag cataaacgat tgaaaaaaag gaaaaatttt cagaaaacta
    20941 aaatcatatc gcttcccatt ttcattttta gaaaggtctg ttagtataaa gaaaaaatag
    21001 acaacaaaac tttaaataac caactttaaa taaccaactt taaataacca acttgaaata
    21061 aacaaattca aagaagaaag atgggaagga aatcaatcag ttgaatgaaa aagaaattct
    21121 ccgattacaa aaagaattga aacgctggga gaacaagtat aaaaagcttc aacaagtctt
    21181 tcggctacaa gaagaaatca ttgctaccta tgaagcggct tatggcgaag cacccggact
    21241 tattgaggaa gaagtacaag taaaagaaag tgaaggaaac agctctttct ttaaaatgat
    21301 ggagaaacgt tcctataatc gcttcaatca agaacaaaaa gcagctatca catatgatat
    21361 gaagaaacat cttcgaatca tagcaggagc tgggagcggc aaaacgcaaa caatctgtgc
    21421 aaaagctgtt tatctgatga cgcaaaaaca agtagacgaa gaacgcatac taatgatcac
    21481 ttttacaagg aacgctgcaa atgaactaaa aaaacgagta gataatttca gccagagaaa
    21541 aaccgctgtc catatcggaa cattccatag tatctttttt aggatataca atgaaatttg
    21601 tcgaaaattt cctgaagtag caatgcaagg aatacaagga gacttttcaa aggatactgc
    21661 acaaaaagtg aatgctgttt tgcaacagct gatacgtaaa tataatcttt atatatttga
    21721 tcaatatgga gaaaaaacga ttgcttctcg gttagactat tggcagaata tgaacctttc
    21781 agtagaagaa atggttcagt tagttaaaga aaaatatgat tccattgata agaatgcacg
    21841 acagccgata tcagaacgac tgtatggatt gctcacggaa ctccaagaac aaaaaagaag
    21901 ccagcaattg ctagagttca atgatgtact ccaaaatctg aaaagcgctt tggagaatga
    21961 ggagatccag cattatatcg gccaaaaata tgattatcta ttcattgatg aatttcaaga
    22021 tactaatcca cttcaatggg aaatcgtgaa acggatgaca aaggaaaaca ggatcaagtt
    22081 gattgttgtt ggagatgatg atcagagtat ctatggattc agaggatcag agccagcata
    22141 catcaagaac tttgaaaaag aatatcctac caaaactctt ttcttattaa ctaattatcg
    22201 ttctcgggca gctattgtcc aaggagcaaa tagattgatc agctataata aaaatgatcg
    22261 gataccaaag gcgatgattc cagcacaaaa agaagcaggt gttatggaag cctatttgtt
    22321 ttctgatact aaagcagaaa gtcagtggct aatcaaacaa attcagacat ttattcaaaa
    22381 aaatgggaaa tataaggaat caatcatatt ataccgatca gcttcacaaa cgcagcagct
    22441 tgtccaatct ctgctgaaaa cgaatattcc ttttgtactg gaagcagata gtccatatga
    22501 aggtatcttt ggtatcaagt ctttccaaca tttctatcaa aaaattgttc attggcaaac
    22561 agcactgaat ctgcaaaaga aaaatcaggc ctaccagcaa ttgctccggc agctgatggc
    22621 agactgctac ctgaaaaaaa gtgaatgcga tcaatacttt tctcctaaat atcaaaatat
    22681 agccgttgca gattatattt tgtcgataag ccccaattta aaatcgaaat ctgcagaaat
    22741 ccgagagttt gaggaagcgt tgcgtaaaac agaccagcat caagaaatct attcgcttgt
    22801 tcaaagctat cttcatctgc cacgtatagc taaggaaatc gaccagagtg atcaagaatg
    22861 gatacgagaa gaagtaaagc agcatgctac tttcagaaga ctccaagcct tatcgcaaga
    22921 aacccaagcg acagctaaag aattaaaaac ccgcttgatt gcttacagac aaggaaaact
    22981 tgatgcacta tgtatccaga gcattcacaa aagtaaaggt cttagttacc gaaatgtctt
    23041 tttgattggt tgtaacgaag gaagtttgcc ttataacgga gcgacagaaa agaaagtaat
    23101 cgactttaat gaaataaaag cagaaccagt gacgacgata gaagaagaac gaagactatt
    23161 ttatgttgcg atgactagag caagaaatcg tctgtatcta tgtgtacctc aaatgaaaaa
    23221 ttcaagaaaa ttgaaagtat cgagatttat caaagaaacc gggagtcgtg tgaaaaaagg
    23281 aaagtgatag aagagagggt gtgacagaag tggtcagttt caagaaa
//
LOCUS       DAXLPC010000038        23051 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.038, whole genome shotgun sequence.
ACCESSION   DAXLPC010000038 DAXLPC010000000
VERSION     DAXLPC010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23051
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.038"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            188..418
                     /locus_tag="ACF3UE_001446"
     CDS             188..418
                     /locus_tag="ACF3UE_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFD3634864.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            515..1816
                     /gene="murA"
                     /locus_tag="ACF3UE_001447"
     CDS             515..1816
                     /gene="murA"
                     /locus_tag="ACF3UE_001447"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFD3634865.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1829..2005
                     /locus_tag="ACF3UE_001448"
     CDS             1829..2005
                     /locus_tag="ACF3UE_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFD3634866.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2140..2436
                     /gene="yidD"
                     /locus_tag="ACF3UE_001449"
     CDS             2140..2436
                     /gene="yidD"
                     /locus_tag="ACF3UE_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFD3634867.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2621..3088
                     /locus_tag="ACF3UE_001450"
     CDS             2621..3088
                     /locus_tag="ACF3UE_001450"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3634868.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3173..4057
                     /locus_tag="ACF3UE_001451"
     CDS             3173..4057
                     /locus_tag="ACF3UE_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3634869.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4171..4407
                     /locus_tag="ACF3UE_001452"
     CDS             4171..4407
                     /locus_tag="ACF3UE_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFD3634870.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4495..4575
                     /locus_tag="ACF3UE_001453"
     tRNA            4495..4575
                     /locus_tag="ACF3UE_001453"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4529..4531,aa:Tyr,seq:gta)
     gene            4582..4653
                     /locus_tag="ACF3UE_001454"
     tRNA            4582..4653
                     /locus_tag="ACF3UE_001454"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4614..4616,aa:Gln,seq:ttg)
     gene            4778..4948
                     /locus_tag="ACF3UE_001455"
     CDS             4778..4948
                     /locus_tag="ACF3UE_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634871.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            5168..5875
                     /locus_tag="ACF3UE_001456"
     CDS             5168..5875
                     /locus_tag="ACF3UE_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3634872.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5934..6578)
                     /locus_tag="ACF3UE_001457"
     CDS             complement(5934..6578)
                     /locus_tag="ACF3UE_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFD3634873.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6704..6991
                     /locus_tag="ACF3UE_001458"
     CDS             6704..6991
                     /locus_tag="ACF3UE_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634874.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7099..7419
                     /locus_tag="ACF3UE_001459"
     CDS             7099..7419
                     /locus_tag="ACF3UE_001459"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3634875.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7500..8814
                     /locus_tag="ACF3UE_001460"
                     /pseudo
     CDS             7500..8814
                     /locus_tag="ACF3UE_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            8811..9530
                     /locus_tag="ACF3UE_001461"
     CDS             8811..9530
                     /locus_tag="ACF3UE_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFD3634876.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9658..10209
                     /gene="raiA"
                     /locus_tag="ACF3UE_001462"
     CDS             9658..10209
                     /gene="raiA"
                     /locus_tag="ACF3UE_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFD3634877.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10431..12965
                     /gene="secA"
                     /locus_tag="ACF3UE_001463"
     CDS             10431..12965
                     /gene="secA"
                     /locus_tag="ACF3UE_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFD3634878.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            13091..14192
                     /gene="prfB"
                     /locus_tag="ACF3UE_001464"
     CDS             join(13091..13162,13164..14192)
                     /gene="prfB"
                     /locus_tag="ACF3UE_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFD3634879.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14297..14983
                     /gene="ftsE"
                     /locus_tag="ACF3UE_001465"
     CDS             14297..14983
                     /gene="ftsE"
                     /locus_tag="ACF3UE_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFD3634880.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14976..15860
                     /gene="ftsX"
                     /locus_tag="ACF3UE_001466"
     CDS             14976..15860
                     /gene="ftsX"
                     /locus_tag="ACF3UE_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFD3634881.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            16012..17460
                     /gene="cls"
                     /locus_tag="ACF3UE_001467"
     CDS             16012..17460
                     /gene="cls"
                     /locus_tag="ACF3UE_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFD3634882.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17797..18654
                     /locus_tag="ACF3UE_001468"
     CDS             17797..18654
                     /locus_tag="ACF3UE_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFD3634883.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18769..19689
                     /gene="pstC"
                     /locus_tag="ACF3UE_001469"
     CDS             18769..19689
                     /gene="pstC"
                     /locus_tag="ACF3UE_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFD3634884.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19689..20573
                     /gene="pstA"
                     /locus_tag="ACF3UE_001470"
     CDS             19689..20573
                     /gene="pstA"
                     /locus_tag="ACF3UE_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFD3634885.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20588..21394
                     /gene="pstB"
                     /locus_tag="ACF3UE_001471"
     CDS             20588..21394
                     /gene="pstB"
                     /locus_tag="ACF3UE_001471"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFD3634886.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21410..22168
                     /gene="pstB"
                     /locus_tag="ACF3UE_001472"
     CDS             21410..22168
                     /gene="pstB"
                     /locus_tag="ACF3UE_001472"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFD3634887.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22181..22858
                     /gene="phoU"
                     /locus_tag="ACF3UE_001473"
     CDS             22181..22858
                     /gene="phoU"
                     /locus_tag="ACF3UE_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFD3634888.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
BASE COUNT         7594 a         3927 c         5039 g         6491 t
ORIGIN      
        1 tttggaataa gggactgcga caagactttt gtctcagtcc ctttttttgc atatttttag
       61 catttatttc ctaaaaaatg taaggggatt cctatatttt taagtatact tgtttttcct
      121 tttatacatt ttatggtatt atcattttat tagttattat aaaacaatcg ttagaaagga
      181 cgtcattatg caagtatacg gaattgatgc ggtgcttcga atcgtgagtc atttggcgtt
      241 tatctactta gccttctggt ctttacgttc gttacgcatt gaaacttttt tcagaccaat
      301 gcataatacg caaattagaa tggcaatcgt acttttttca atttttttag ggtacactgc
      361 aagtaatttt ttcttagaag ttatcgcttt atgccgaaat cttttcgtta gcctgtaaat
      421 tttaaaaaaa ggtactattt taaaagcaag gatgttataa tagaaaagat tttgagtaag
      481 tgtatgctca ttggaatttt ttggagggaa caacatggaa gagatcatcg taagaggtgg
      541 caatcaatta aatggaacag taagaattga aggagctaaa aatgctgttt tgcctatttt
      601 agctgctagt ttgttagcag aagaaggtat tacgacatta gacaacgttc cgattctttc
      661 tgatgtcttc actatgaatc aagtgattcg tcacttaaac gtagatgtag attttgatga
      721 acaaaagaat caagtaacaa tcgacgcttc aagacaatta gaaatcgaag cgccttatga
      781 gtatgttagt caaatgcgtg cttcaatcgt tgtgatgggt ccgctacttg ccagaaatgg
      841 acatgcaaaa gtagctatgc ctggtggatg tgcgattggt aaacgaccaa tcgatttgca
      901 tttaaaagga tttcaagctt taggagcaaa aattattcaa aaaaacggct atatcgaagc
      961 aattgcggat gaattgatcg gtaacacgat ttatttagat ttccctagtg taggtgctac
     1021 tcaaaatatc atgatggctg ccgtaaaagc aaaaggaaca accatcattg aaaacgtagc
     1081 tcgcgaacca gaaatcgttg atttagcaaa cattttgaat aaaatgggcg ctcaagtcta
     1141 tggagctggt actgaaacaa tgcgtattga aggcgtggat catttacatg cagtcaacca
     1201 ctcaatcgta caagatcgta tcgaagcagg tacctttatg gttgctgctg caatgacaca
     1261 aggcaatgtg ctgattgcag atgctatctc tgaacataac cgcccattga tttctaaatt
     1321 gatcgaaatg ggtgcagaaa tcattgaaga agaaggcgga gtccgtgtca tcggaccaaa
     1381 acatatctta cctacagatg taaaaacgat gcctcatcct ggtttcccta cagatatgca
     1441 agctcaaatg acagctatcc aattagttgc agaaggtaca agtgtagtga ctgaaacagt
     1501 gtttgaaaat cgtttccaac atttagaaga gatgcgccgt atgaacgctc atgtcaaaat
     1561 cgacggaaat gtagcaatca tggatggaaa ccatgaattg caaggtgcag aagtatatgc
     1621 aacagacttg cgggcagcag cagcattagt tttagctggc ttgaaagcaa atggaatcac
     1681 acgtgtgcgt aacttgaatt atctagaccg tggatattat aatttccata tcaaactaca
     1741 gcaattaggt gcagacgttg aacgtgtaga catggatcaa acttctgctg aaaaaacagc
     1801 acaaacgatt gcttaaggaa gtggctgaat gagtaaccaa cgatatatct tattaacttt
     1861 gataaagatt ttaatggtga tcttattgct tatccttctt tttgtggccg gaacgatgat
     1921 cggatatggt gtcatcggtg gcggcaatcc atttaaagta tttcagccaa gtttgtggat
     1981 tcatattcga gacttttttc attgataaat aagaatcaca gtggttctag tcgatatgaa
     2041 gtgagccatg aagcagaaca tgataaaaga aaacagaagg gaacgttgac gttagtcgcg
     2101 atcccttttt ttagtaaaag aaaagaagga atctaattga tgaagaagat attgatttat
     2161 ttagttagag gatatcagcg ctttatttcg cctgcatttc cacctagctg ccgttattac
     2221 ccaacctgtt ccaattatat gataaaagca attcaaaccc atggcgcgct aaaagggacg
     2281 gtaatgggga ctgcacggat cttacgctgt catccttttg tcaaaggcgg tatcgattat
     2341 gtaccattga cattccgatt aacgcgaaat aagaaagata aaaaagaacc agattataaa
     2401 aaggttgtga aaaatacggg tagcactgag cgataaagaa acaatttgga aaatagcttc
     2461 ttatattttg caaaattgtg agttattgcc gaagtgttgg attttgaaca ccgtcaaaaa
     2521 aaaggttgtg aaaaatacgg ctagcactga gcgataaaga aaaagaggaa atttattgtc
     2581 aaagtaacaa ctccgcaact acttatatgg gggacaaaaa atgatcgaag aactaaacaa
     2641 gaaagattta ccatggtcct tgttattaga tgcagatcct gataaagaaa aagttcaagt
     2701 atatgtttcc agagggagtg gctggatatg gaaagaaaaa gaaaaaacaa taggtgtact
     2761 gatctatgtg gcaagggaaa aagaatacga aatcgtcaat gtagcagtaa ccccaacgta
     2821 tcaaggaaag gggattggcg gaaaattact tgagacagct tttcagaagc tttcacaact
     2881 cgcttccagt caaactcaga tcatcatacg aaccggcagt actagcagtg cggcgttaca
     2941 tctctatcaa aaaatgggct atgtggagat tggtcgagtc aaagactatt ttatccatca
     3001 ttactctgag cccatttttg aaaatggaga tcaattaagg gatcaagtga ttttagcaat
     3061 tcacttacct aaaaatagct ttaactaata aaatttcaat tcaagaaaat gctttcaaat
     3121 gctaaataga tacattacaa tagctttagc aaacaaaaag gagaatattt ttatgggaat
     3181 attagttttt gattttggtg gatcggctgt caaatatggt tgttgggatg gcaaagagat
     3241 taaaggtaag ggacaatttg caacgcctga atcttgggaa gaaatgaaag cgcaattatt
     3301 tcaagtttat aaaaaaatac tcgtttcttt tgaagtcgaa ggaattggaa tcagctctcc
     3361 tggagtagtg aataatgaga aacaggtgat tgagggaatc agtgcgattc cttatattca
     3421 tggatttaat attttccgag atttggaaac tctgtttcaa cttccagtaa cgattgaaaa
     3481 tgacgccaac tgtgccggaa tggctgaatt ttatgaaggt gctgcccgcg attatcaaga
     3541 tgttgctttt gttgtggcag gaactgggat tggcggggcg ttgttcacga aaggacaaat
     3601 caataaaggg gcacatcttt acggtggaga atttgggttg atgttcttaa atggcgataa
     3661 gacattcagt aaacttggta cagcggtaca gatggcttgg cgttattgtg aacgcaaagg
     3721 tctcgataaa aatgcttata ccggaaaaga tgtctttgaa ttagcagaaa ctggagatgc
     3781 aatagcaaaa gaagaagttg agagttttta tacgtatctt acaaagggat tattcagtat
     3841 tcaattttcg tttgatccag aagtgatcgt attaggcggc ggggtttctg caaaagaagg
     3901 gctcattgat gagatcaaaa gccgaatgaa gaagctgaca gaacaattcg atctgcatga
     3961 tttcgaaccg cagattttat tatgtgaata cagaaacgat gctaatcttg taggtgcagc
     4021 agcaaactat ctcgctgtac gtcaagggga gaattaagag ctttagagaa ggtgcagctt
     4081 gcataaaaga agtgaatgaa atgaatagga gatttttacc taaggaatgt tttatttgct
     4141 gcagtatgat aaaatatctg agaggtgaaa atgatgtcaa aaaaaaataa agatattgaa
     4201 gtgcgtatag aagaagtgaa aaaagatatc aaaggtaaga attatgaagt cactcagtta
     4261 tttataggga aaaaaatgat tggtgagatc ttagcctatg gaccaaaaga atatgaaatt
     4321 ttctttggtg aagaagattt tggaaaagaa aaaagtcttg aaaatgcgat agaaacagtg
     4381 attcgacact ggaatctgca cgaataaaaa aatatcaaaa aaactttcaa taaagggttg
     4441 caaaaatctg gaaaattagg tattataact aagtcaggtt gatacaaacc tttcggagga
     4501 gtagcgaagt ggctaaacgc gacggactgt aaatccgttc cttagggttc agtggttcga
     4561 atccactctc ctccatttca ttggggtata gccaagcggt aaggcaaggg actttgactc
     4621 cctcatgcgt tggttcgaat ccagctaccc cagtatacca caatcgtaag ctctcgttag
     4681 ttcgagagct cttttttttg ctttgctacc ttgttccttg aagattctgc tgatttaaga
     4741 tagagttaag ttaactacaa gaattggagg gatccacatg aaatggaaag aaaaagtaga
     4801 cgaagcagct gaaaagttat atgatttggt caaatcagaa aaatacaata ttgaagtgaa
     4861 tattccgaaa aaaggcggaa aagcggtccg ggtaaaatca aaacgcccaa cgaatcatac
     4921 aaaaaaatgg atggctaaaa accgctaata ataacaaaag atccataagt cggcattttc
     4981 atcgatttta gggtcttttg ttattttcta ggttggacat atctaaaaaa ttgtttctga
     5041 caataggagt aggaagaacg atgtgtgtct aaatcctctg ttgatggata gaaaccttta
     5101 tctttttcag ttgtgaatca ggtatatacc agttataata gaagaaacga aaggacgggt
     5161 gtacgttatg tcgaatcaat tacctgtata tatacagatt catgaccaat taaaaaatga
     5221 aatcgaacaa ggtatatgga aagtcggaga ccgtcttcct tcagaaagag aattagcagt
     5281 gaaattcaat gtcagccgta tgacgttgag acaagcaatt caaaacttgg cagatgaagg
     5341 aatcttagaa agaaagatcg gttcgggtac atatgttgca cgagaaaaag tacaagaaaa
     5401 aatgtctggt gcaacaagtt ttacagaaat tatggaatca caaaatcgag taccgtctag
     5461 tcggacaatc tcttatttct tgacttcgcc aagctcaagt gaaatggaaa aactaaactt
     5521 gagtaaagat gacacgatct tgcgaatgga acgtattcgt ttcgcagatg atgtccctat
     5581 ttgttttgaa gttgccagtg tgccacaaaa gctgatcgat ggctacagca aagcagagat
     5641 tactgaatcg ttgtatcgca cgctagaaga aaaaggcggg aaaaagatcg gtccagcgaa
     5701 tcaaacgatt actgctgtgt tggcttctga gaaaattgct gactatttag aggtaaaacg
     5761 aggagatgca gttcttcgtt tgcgccagat ttcttatttt gaagacggta cgccgtttga
     5821 gtatgtgcgt acgcaatacg taggaaatcg ttttgagttt tatttggaaa aataaaaaac
     5881 aggtgatccc tgattccgta ttagaaataa aagagaatca gaatcacctg tttttatata
     5941 tgatcagtta ccagttgctc gtgataagaa acaggaccct cttcaaattg gacttgtccg
     6001 ttcagcagct caatgatgga ttctttaaag tggtcagcac ttttttcatc tacagcacag
     6061 atgacgctaa cttgatcagt atattggatt tcttttataa aaaaatgttg gagttcaaga
     6121 taattctgta attttcctag ttgcggatac gtgatcatca cagagatctc ctgttgcaag
     6181 gtaccttcta cgattccaat gtcagacaat gcttgagaga ccgcatgagt gtatgctcgt
     6241 attaatccgc ctgtgccgag tttcgttcct ccaaaatatc gagtgactac tgcagctaca
     6301 ttgatcagtt gatttttttt gaggacttcc aacatcggta tgcccgccgt tccacttggt
     6361 tctccatcat cgctgcttcg ctggatttca tttttttctc caatgatgaa ggcgctgcag
     6421 ttatggttcg ctttccaatg ttcttttttt atttcttgaa tgaaactttt tgcttcgtcc
     6481 tctgattcta ttcgtctaag agaacagata aagcgtgatt ttttgatctc gatctcactt
     6541 tgtccatttt cttttattgt acgatagcgc tcgatcatct tgtcacctct tttttcattt
     6601 tctttattca gtataaataa agttctaggt tgtttcaaca ctgtaacggt tgcgcaattg
     6661 ctgtagtatg cgataataaa gacaaaggca ggtggatctg gggatgcagg aacgaatgaa
     6721 aaagtacgat gcaattacgc attatttgaa gaacaatggc ggctctcaag taacgttgac
     6781 ctttacccaa tttgacgaac tgctgtttcc cagtaacgga cttcccaaaa cagcaaggga
     6841 aagtacagat tggtgggcaa atgattataa acaccctgaa aaaggtgcct atggctggat
     6901 aaatgcaggc tatgaagtag ttgtcatcaa tttggacaaa gaatatgtcg tgttcaataa
     6961 attagtgaaa tctagttggc tatttgatta aataaaccgc gtttagaaaa cgttgacaaa
     7021 tttctttctt tttatataat agagtaacag acgcgaagaa aacgtttgcg tagtttgttt
     7081 taaaaaggag agaaaagtat ggctaaaaaa acaatcatgc ttgtatgttc ggctggtatg
     7141 agcacaagtt tactagtaac aaaaatgcaa aaagctgctg aagcaaaagg aatcgactct
     7201 gatattttcg ctgtgtccgc ttctgacgca gataacaatc ttgcaaataa agacgtggat
     7261 gtgttgttat taggcccaca agttcgcttt atgaaagctg attttgagaa acgtctggaa
     7321 ccaaaaggca ttcctttaga tgtcatcaat atggctgatt atggtatgat gaatggcgaa
     7381 aaagtgttag atcaagcaat cacgctcata ggtgaataaa tagaacagta taactatcga
     7441 acaagcgatc caaaaaatag atcgcttgtt ttttcgtata tttttttagg gcgaataata
     7501 tgaatcattt ttggggtaga aggcttctga cgagagatat taaagcaata gactgtgagg
     7561 aggtaaattt accaaattat gagaagatcg cagcagtgga acgtttgagc aactggattc
     7621 tttgtcatcg ctgtggaatg agaacgtccg tcattgatgg acagcttgca gattacggtt
     7681 atttttgtac acattgtcta tatttagggc gatgcgacac tcaacaagat ttatatttgt
     7741 ttgatcagcc tgaagcaaaa cctcgagaag tcgtcttttt tttggacagg acagcttact
     7801 gaaaaacaaa cggaaatctc aaagagaata ctttgccatt cagaaaaaag acatcatctt
     7861 atttgggctg taacaggtgc agggaaaaca gagatgcttt atcctatttt agtggaaact
     7921 ttaaaagctg gaggaagagt agcgatttgt acaccgcgag tcgatgtttg taatgaattg
     7981 tttttacgct atcgttatgt ttttccagaa gaaaaaatca cgttgctcca tgggaataca
     8041 gcaacggctt atacctttac ttcttttgtt atctgtacga ttcatcagct ataccgtttt
     8101 tatcggtcct ttgatttaat agtgatcgat gagatcgatg cgtttcctta taacggggat
     8161 gcaggattag ctcatgctgt gcaaacagcg attaaaccag acggacgatt catctactta
     8221 agtgccacac ctgataaaaa gttactaaag gagatcaagc agacgtttga catccacaaa
     8281 cttgctttac gctttcatcg gcgtttgctt cctgaacccg tcttggtttt catgaataat
     8341 tggcgacaaa aatgcaagaa caagaagaag ataaaatctt tggtgcggat cattcatcaa
     8401 ttaattaaag aaaaccatat ccttttattt tgtccaagta tcacgatgat gcatcgtttg
     8461 aaagccacac ttcaagaggc tcttccgaga tatgagatca cagatgtttc ttcaagagac
     8521 aatcagcggg cggaaaaagt ccagaaaatg cgagaagcaa aatatgacat actgttaacc
     8581 acgatgatcc ttgaacgtgg agtcacattt gaaagaatat ccgttatcgt tttaggagcg
     8641 gatcatccgg tttttactaa atcttctttg gtacaaatcg caggaagagc cgatcgtaaa
     8701 gggccttata cgaacagtca agtatatttt ttctatgaag aaaaaactgc agctattcga
     8761 aaagcttgtc aggaaatcaa agaaatgaat gaagaaggga agaagatact gtgaggtgca
     8821 gttgctgcag taaagatatc gtccaaaatt taacattcag cgagattatt ggtgtttcga
     8881 aatacagatt acctcagact tgttcagttt gtcgcgcaca atttcattta ttggaaacaa
     8941 gaggctgttc tggctgtcaa aaaccaatcc atttcaatct agagagtacg aaaaagaaag
     9001 taaattctat ccccgtttac tgcagtgact gtcaagaatg gaagaagaaa tatccgacct
     9061 atgattttca gcaccgtgcc ttttttgtgt acgatgaaaa tatgaaggcc tggctcaatc
     9121 aatacaagtt tatgggagat atccgactag caggcacctt tgcatataaa tggacgcaga
     9181 taaaaaaaga atacccgaca tacatctatt gtccaatacc tttatctgaa aaaaggcgaa
     9241 cagaaagagg attcaatcaa gtaagcgaga tgttgaaagc agcaagaatt ccttttcaga
     9301 tgctactcaa aagagagaag catctgctgg ctcaagcaaa aaacacgcga aaggaaagat
     9361 tggagatgcc tcaacctttt gaacttgcag tcaccttttc taagatacaa aataaaaaaa
     9421 tattgattat tgatgatgtc tatacaacag gacagactct tttccacgca gcagattgtt
     9481 tgcagatcgc acagccgaaa atcatccgaa ctatttcttt ggcgagatga attagatgtg
     9541 gaaatttgat agcgatttaa tttgcaaata acctagagtt cgatataata gaattaagaa
     9601 gagggaaaga gtggtccttc tccttcttga ttgtggtaga cgaaaggggt aatttttatg
     9661 tttagatata atgtacgcgg cgaaaatatc gaagtaactg aagcgattcg cgactacgtt
     9721 gagaaaaaag taggcaaact agaacgctat ttcagtgacg cacccgatgc aacggcgcat
     9781 gtgaacttaa aagtttatac agaaaaaaca gcaaaagtgg aagtaacgat cccattacct
     9841 tatcttgtat tacgtgccga agaaacttct ccagatttat acgcaagtat cgatttggtt
     9901 gttgacaaat tggaacgcca aatccgcaaa ttcaaaacaa aaattaatcg taaatcccgt
     9961 gaaacgggca tgaatactgc aaatgctgct gctttattca atgaagagga cgaaaacgaa
    10021 aatgattctg aattagatat cgtacgtacg aaacgccttt cattgaaacc aatggatagt
    10081 gaagaagcag tcttgcaaat gaacatgctg ggacataact tctttatttt tgaagatgca
    10141 gaaacaaatg gtacaagtat cgtttaccgc cgtaaagatg gaaaatacgg actgattgaa
    10201 acagactgat cagccttact taaataacaa cgaaaacttg cagcagctac tgacagctgc
    10261 cgcaagtttt tttgagtttc ctcctctttt agatgaaata tgaataaatt atgaagttct
    10321 tactttaata cgcttaagat atttcaatta tctataacta atgataaaat gaaaagtaaa
    10381 gtctacatag tctggataat acacagaagg aaaaggagat tacacaacgc atggccaatt
    10441 tgattcgttc acttatcgaa aacgataaga aagaactaaa acgtttagat agcattgcaa
    10501 aaaaagttga agcatacgct gaccaaatgg cagcattaac tgatgaacaa ttacaggcaa
    10561 aaactgctga attcaagggc agataccaaa aaggagaaac attagatcaa ttacttccgg
    10621 aagcttttgc agtcgtccga gaagcagcaa aacgtgtatt aggtttatat ccataccacg
    10681 tacaattgat gggtggaatc gtgcttcacg atggaaatat ccctgaaatg cgtactggtg
    10741 aaggtaaaac cttgaccgca acgatgccag tatatctaaa tgctctgact ggcgaagggg
    10801 tacacgtagt taccgtcaat gaatatttag caacccgtga ctcgacggaa atgggcgaac
    10861 tttataattt cttaggatta acagtggggt tgaatatcaa ctcaaaatct tcggatgaaa
    10921 aacgcgaggc ttataattgt gatatcactt atagtacgaa taatgaatta ggatttgact
    10981 acttgagaga caatatggtc gtttaccgcc atcaaatggt acaacgtccg ctgaattatg
    11041 ccattgtcga tgaagttgac tcaatcttga ttgatgaagc gagaacgccg ctgatcattt
    11101 cagggcaagc agaaaaatcc acagctttat atacaagagc agacaacttc gtgaaacgtt
    11161 tgaaagaaga agaagattat aaaatcgatg tacaatcaaa aacaatcagt ttaaccgaag
    11221 cagggatcga aaaagcagaa gaaacattcg gtttggataa cttatacgac attgaaaata
    11281 ctgcattgac ccatcacttg gatcaagcat tgagagccaa ctatatcatg cttttagata
    11341 tcgattatgt tgtccaagac ggaaaagtac tgattgttga ccagttcact ggtcggatca
    11401 tggatggacg ccgttattca gatggacttc accaagcaat cgaagctaaa gaaggcgtag
    11461 agatcgaaga cgaaacgaaa accatggcga cgatcacttt ccagaactat ttccgtatgt
    11521 acaagaaact tgcgggaatg actggtacag ctaaaacaga agaagaagaa ttcagagaaa
    11581 tttataacat ccaagtatac cagattccga caaatcgtcc ggttatccgt gatgatcgtc
    11641 cagatttgct ttacccaaca ttacaaagca agttccacgc tgtcgtgcaa gatatcaaag
    11701 atcgctaccg caaaggtcaa cctgtgttag tcggaactgt tgcggttgaa acatctgagt
    11761 tattatcaga tatgctgaat caagaacgta ttcctcatga agtgctgaat gcgaaaaatc
    11821 actttaaaga agcagagatc atcatgaatg ctggtcaaaa aggtgctgtg acgattgcta
    11881 ccaacatggc tggtcgggga acagatatca agttaggact tggggtaaga gaacttggtg
    11941 gtctagcagt tatcgggaca gaacgacatg aatctcgtcg tatcgataac cagcttcgag
    12001 gacgtgcagg acgtcaagga gaccctggta tgtcacagtt ctacttgtca ttggaagatg
    12061 atttgatgaa acgattcggt tcagaacgaa tcaaatcttt cttagatcgg atgaagatcg
    12121 gtgaggaaga tgctgttatc caaagcaaga tgctgacgaa acaagtagaa tctgcacaaa
    12181 aacgtgtaga aggaaataac tatgacacac gtaaaaacgt cttacaatac gatgatgtga
    12241 tgcgtgaaca acgtgaagta atctataaac agcgacaaga agtaatcatg gaagaaaaaa
    12301 gcttatccaa gccactaatg aacatggtca aacggacaat cagtcgtgta gtagatgcgc
    12361 atacacaatt agagaaagaa aattggaatt tggaaagtat catcgatttt gccggcagta
    12421 ctcttgtcca tgaagatagt attactcttg cagatatcga aggaaaaaca gctcaggaga
    12481 tcaaagagta tctaaacgaa cgagcacaag aagtatttaa taccaaagcg gctcaactaa
    12541 atggtccaga gcaactgttg gaatttgaaa aagtcgtgat cttgcgtgtt gtggactcta
    12601 aatggacaga ccatattgat gcaatggatc aattacgtca gtcaatcggc ttacgtgctt
    12661 atggacagaa caatccatta gtcgaatatc aaacagaagg ctataagatg tttgaagata
    12721 tggtaggcgc catcgagtat gaagtcactc gaatctttat gaaagctgag atccgtcaaa
    12781 acgtacagcg tgaacaggtt tctcaaggaa cagcttctca ctcagaagac ggagatgcca
    12841 aagaaaatag taatactagc gcgaaaaaac agccaatcca tgtgaacaag gtcggaagaa
    12901 atgatccttg tccttgtgga agcgggaaaa aatataagaa ctgtcatgga aaaaatgcaa
    12961 actaatttct gacagcagga ttggtgagac aaattctttt tttaagaatt cgtctcacct
    13021 tctttctgtt atttgctgat tctgttagac tagatataat gaaaaaagta tagtgaaaga
    13081 aggaaaaaac atggaaatat ccgaaattcg aaatctcctg acagaaatgc aggaaaaggt
    13141 cacaagcttc aggaggtctc tttgacttag accagctgga agaagacatt gcggaagcag
    13201 aagcaaaaat ggctgaacct ggtttttggg atgatagcga agctgctcaa aaagtgatca
    13261 gtgaaaacaa tgcaaataaa gaaacttatg atcaattcca ttctcttgct gaagaactgg
    13321 aagaaatcga attgatggtg gagatgttgc aggaagaacc tgatgcagcc atgcaagaag
    13381 aagcagaaac acgtatcaat gcgctagatg aaaaaatgaa gacatatgaa ttatctatgt
    13441 tgttagatgg tccttatgat cgaaacaacg ccatcgttga attgcatcca ggggctggcg
    13501 gaacggagtc ccaagattgg ggcagtatgc ttttacgtat gtatacacgc tgggcagagc
    13561 agcatgggta tcaagtagag acactagatt atcaagcagg tgatgaagca ggaatcaaga
    13621 gtgtgaccct actgatcaaa ggacacaacg catttggtta tctgaaatca gaaaaaggtg
    13681 ttcatcgcct tgtacgtatc tcgccttttg actcagcgaa acgacgtcat acttcttttt
    13741 gttcggtaga tgtgatgcca gagcttgatg aaacgatcga tatagaaatc aatccagatg
    13801 atttgaaaat cgatacgtac cgagcaagtg gtgcaggtgg tcagcacatc aataaaacag
    13861 aatctgctgt acggatcact cacttgccta caggaacagt agtagctagt caggcacaac
    13921 gttcacaatt gaaaaaccgt gagcaagcga tggggatgtt aaaagctaag ctttatcaat
    13981 tagaagtgga aaagaaagaa caagaagcag ctgcacttcg aggagaacaa aaagaaatcg
    14041 gctggggttc acagatccgt tcttatgttt tccatccata ttctatggta aaagaccatc
    14101 ggacaaacgt agagacagga aatgtccaag cagttatgga cggtgacctt gatttattta
    14161 ttgacggcta tttaaaaatg catctacaat aagaacccat tgttaaattg aaataaaatt
    14221 gtaagatttt gcaagcatgt tgaaacattg ccatgctata atagctaaag actgaaaaag
    14281 atatggagag aacgccatga ttgaaatgaa ggatgtaatg aagaagtact caaatggtac
    14341 gaccgctatc cgcaatctct caattgtcat cgaacaagga gagtttgtct atgtggttgg
    14401 tccgtctgga gccggtaaat ctacattcat caaattgatg tatcgagaag aaaaagcttc
    14461 aaaaggaact ttgaacgtcg caggtcatga tctaatagca atcaaaaacc gcgaagttcc
    14521 ttatctacgc agagaaatcg gcgtggtgtt ccaagactat aaattattac caagaaaaac
    14581 agtatatgaa aatgttgcgt acgctatgca agttatcggc agaaaacctc gggatatcaa
    14641 aaaacgagta atggaagtgc tggaccttgt tggtttgaaa cacaaagttc gagtctttcc
    14701 tagcgaatta tccggtgggg aacagcaacg tgtctctatt gctcgggcaa tagtgaatac
    14761 gcctaaagta cttatcgcgg atgaaccgac aggaaatctg gatccagaaa actcatggga
    14821 aatcatgaaa ttattagatc ggatcaatgc ccaaggaact actgtcgtga tggctacaca
    14881 taacagtacg atcgtaaata cgattcggca ccgagtaatt gctatcgaaa acggccgcat
    14941 tattcgagat caagcggaag gggaatatgg atacgatgat tagaaccttt ttccgccatt
    15001 tattagaaag tatcaagagt ttgaaacgta acggctggat gacagttgct tcagtcagtg
    15061 cggtaacgat cacattgact ttagtcggtg tattcatggc agttatcatg aacgcaacta
    15121 aattagctca agatatagaa ggaaacgttg atgtctctgt attcgtagat atcggtacaa
    15181 aagacgaaga gatgaaaaag ctagaaaaag aattgaatga cttagatcat gttaaaaaag
    15241 ttgaattttc aagcaaagaa caggaattga aaaaaatcca aaacgaaatg ggtgattcct
    15301 ggaaattgtt tgaaggtgac aataacccgt tatatgatgt gtatgtagta agtgctactg
    15361 atccttctta tacaaaacaa gtagcagaag aagcagcaga tttgaagaat gtttctcgtt
    15421 ctgattacgg tggagcttcc tcagatcgga ttttccaaat cgctggtgca gttcggacat
    15481 ggggattagt tgcagcggca ttgctgctgt tcgtagcgat gtttctcatt tcgaacacga
    15541 ttcggatcac gattttgtct agacagcgtg aaattcaaat catgcgttta gtcggtgcaa
    15601 aaaatggata tattcgctgg ccgtttttcc ttgaaggtgg ctggatcggt ctgatcggtg
    15661 cgattcttcc gattttgatc atcacatttg gttatgcatg gtttttccaa ttgatcaatc
    15721 catcattatt acgttcccat tattcattga ttcatccaca aaatatcgtt tggaaaatca
    15781 atcttttaat ggtcggcatt ggtgtgatca ttggttcact tggctcgatc atttctatga
    15841 gacgtttctt gaaattctaa taccacaata taaataaaat gagaaagttg gacagtttcg
    15901 ttccagcttt ctttttttat tggctaggag aatagaagga agcggctttt ttccctttac
    15961 tttaaaaaac aacttgggta ttcttaagtt ggtagaagaa gaggtgaagc cgtgaaaatt
    16021 atcgttgaca atttttttac gatccttttg attatgaata ttttgctttc ctttatcatc
    16081 gtttttcgag aaagaaagga aactgctcaa acatgggcat gggtgctcgt tttgatgttc
    16141 attccagttg taggatttat tttatatatt tttttaggaa gagggatttc caaagagaaa
    16201 atctttgatt tgaagatcca agggaaaatc ggtaagaacc tggaaattga agaagacaaa
    16261 caggcattga tgcgagggct ttatcctcat ccgcctactg gacaagtaga tgtgaaacaa
    16321 ttgatctata tgctcacggt atttgaaagt acgctctata cgactaaaaa tgaaatcact
    16381 ttatttacag atggtcgtga aaaattcgat gcgctgattg aagatatcaa gcaggcagaa
    16441 gaccatatcc acttccagta ttatatttat cgcagtgatg cattaggtga agaagttcga
    16501 gatgcattga cagaggcggc aagacgaggg gtaaaagtca gagtccttct tgatgcatgg
    16561 ggttccacac aagtttcttc cagctttttt cagaatttga aaaaagcagg cggagaagtc
    16621 gcatttttct ttcctctatt tgttccgtat attaatcctc ggatcaatta tcgcaatcat
    16681 cgtaaaatcg tagttattga tgggaaaatc ggatatacag gtgggttcaa tgttggaaat
    16741 gaatatctag gattggtaaa gaaatttggt tattggcgag acaatcattt gcgtatttac
    16801 ggagaagcgg tgtatacctt gcaaaaccgt tttttgatgg actggaattc tcagcataca
    16861 aaagaagtag gctattctcc caaatttttt ccgtccattc actctactgg tgatatagct
    16921 gttcaaatcg tgacaagcgg accagatacc gaacatgaac aaatcaaaat gacttatttg
    16981 aaaatgattt cgttagccaa acgggagata ttgatccaaa cgccttatta cataccggat
    17041 ggatcgattc atgaagcact gaagttggct cttctttcag gcgtaaaagt tcatatccaa
    17101 atacctaaca aaccagatca tcttctcgtt tactgggcaa cgtattcttt cgctgcagag
    17161 ctaatcgagt atggagcaag gatcgaaaca tatgagaatg gatttattca tgcaaagacg
    17221 atgattatcg atggtggcat tgtttcagtt ggctcagcaa atatcgatgt tcgttcattt
    17281 cgcttggact ttgaggtcaa tacactggtt tatgatgaac gaatggcttc acgtgtaaga
    17341 aaagcttttt ttgaagactc gaaaatttct acgcatctca caaaagaaat gtatgaaaac
    17401 cgaggaataa tcatcaagat gaaagaagga ttagcaagat tgatttcgcc gctcctttaa
    17461 aacataaaaa ggacatgaga accatcaaca gatggagatc tcgtgtcctt ttctaacggg
    17521 gccatttctg agagtacgtc agaaatggag aaagcgtctc gcatgagcga aattaacttt
    17581 ggggtatctc ttgttttttg gggaaagcaa gaaataagct aatatatgct attaaaagag
    17641 acacatttca aagccagtat agcatagaaa cttttaatga gatagttttt tttacaatta
    17701 tgagaattta ttttgttatt taatgatttt gattcgtttt catcaagtaa tgaaaatgat
    17761 aaaataaaca tactttagga ttaaaggaga tttctaatga aaaaacttaa attattctta
    17821 ccaataatag gattagctat tcttttatca ggctgttcaa agtggattga tcgaggagaa
    17881 tccattacgg ctgttggctc ttctgcttta cagcctttag tagaaacagt tgctgaaact
    17941 taccagacag aaaatcctgg aaaattcatc aatgtacaag ggggcggaag cggaactggt
    18001 ttgtctcaag tacagtcagg agcagtcgac atcggaaact ctgatttgtt tgcggaagaa
    18061 aaatcgggga tcgatgcctc agcattagtc gatcatcgag tagcagttgt tgggatcact
    18121 cctattgtga acaaggatat tggcgtaaaa gacatcagta tggaaaacct gaaaaaacta
    18181 tttacaggcg agatcaaaaa ctggagtgaa gtcggtggaa aagatcagcc agtagttata
    18241 ttgaaccgcg cttcaggaag cggaacccgt agcacgtttg aaaaatgggt attggacgga
    18301 gaaacagctg ttcaggcaca agaacaagat tcaagcggaa tggtgcgcca gatcgttgcc
    18361 gacacacccg gtgcaatcag ctatgttgct ttttcttatg tttccgatga tgtagatacg
    18421 ttgaatgtta acggtgtaga accgacagat gaaaatgtga caacgaacaa atggacgatt
    18481 tgggcatatg agcatatgta cacaagagat catccaaaaa aactgacaaa agaattttta
    18541 gactatatct tatctgatga agtacaagat aacatcgttg gagaactagg ttatatccct
    18601 gtttctcata tgaaagtcga acgtgattgg caaggaaata tcgttaaaga gtaatcttta
    18661 cacaaaattt acaaacttag ctaaactttt acatgttatt aaaaccaaat tgatgttcaa
    18721 tttgtacact gagtgagtat gttaaacctg attaaggggg agtcatctgt ggaagatgtg
    18781 aaaaaagtat tattaacaaa atcaaaacgt tcaaaaatgg aacagcgtgg aaaattcatc
    18841 agttttttat gtatcgcgct gatcgtgttg gttgtattat ctatttttta ttttgtagct
    18901 agtaaaggat tggccacctt ttttactgat aagatcaatg tatttgattt tctgtttggt
    18961 acagattgga atccaagcca aatcggagca aatgggaaac caatggtagg ggcattgcct
    19021 atgatcacag gttcgtttat tgtgaccttt ttatctgcta tcgttgccac gccatttgcc
    19081 attggtgcag cagtattcat gacggagatc tctcctaaaa acggaacgaa gatcttacag
    19141 ccggtcatcg agctgcttgt aggtattcct tctgtcgttt atggttttat cggtttatca
    19201 gttatcgtgc cttttgtcag aagtattttt ggcgggactg ggtttggtat cttagctggt
    19261 acatttgtgt tgttcgttat gatcttgccg actgtcacaa cgatgactgt tgatgcatta
    19321 aaggcagtgc cacggcacta tcgggaagct tcattagcgc ttggtgccac aagatggcaa
    19381 acaatctaca aagtcgtgct acgagcagcc gtgcccggga ttttaacagc agtcgttttt
    19441 ggtatggctc gtgcgtttgg tgaagcctta gctatccaaa tggtcatcgg taatgcagca
    19501 ttgatgccaa caggtcttac tactcctgct tctacattga cgtccatctt aacaatggga
    19561 atcggaaata caatcatggg aacagttgaa aataatgtgt tatggtcatt agcgctgatc
    19621 ttgctattga tgtcattatt ctttaatatc gtgatccgta tgattgggaa gaaaggagag
    19681 ctgaaataat gaacgcaaaa cgctcagata aaattgctac aggtgtttta tatatagttt
    19741 cggggatcat cgtattgatt ttagcagctt tactacttta tatcttagtt cggggaatac
    19801 cgcacatttc atggtccttc ttgaccgaac cttccaaagc ctaccaagaa ggcggtggaa
    19861 tcgggatcca gctatttaac tcgatttatt tgcttttgat cacgatgatc atcagttttc
    19921 ctatttcttt aggtgcgggt atctatcttt cagaatatgc tggaaaaaac tggctaacag
    19981 atgtgattcg cacgtcgatt gaaatcttga gctcgttgcc ttctgtcgtt gtcggtttat
    20041 tcggtttctt ggttttcgtt attcaattcc agtatggttt ctcgattatt tctggtgcat
    20101 tggctttgac tgtattcaac ttgcctcttt tgactagaac agttgaggag tctttacaag
    20161 cggtccatta cacacaacga gaagcaggat tggccttagg tttgtcacgc tgggaaacag
    20221 tgataaaagt ggtggttcca gaagcgacac cagggatttt gactggtgtg atcctaagtt
    20281 ctggaagaat ttttggtgaa gcagctgcat tgatctatac ggctggacaa agtgcacctg
    20341 cgttagattt tacgaactgg aatccattaa gtgtttcaag cccgatcagc attttccgtc
    20401 aagctgaaac attagctgtc catatttgga agatcaatac agaaggcacg atgcctgatg
    20461 gtgtttctgt ttcggctggc gcttctgccg tgttgattat tgctgtttta ctgttcaact
    20521 tcggcgctcg tgcgattggc aaacgattat accgaaaaat gacttcagcc taaggagaag
    20581 aagcaaaatg aaaaaatata actggaatga aacaaatgtc atcaccatgc caaaagagaa
    20641 agaagtagca ctatatacgg atgatctaca tgtctggtat ggcgacaatg aagcaatcaa
    20701 aggagtggat ctggaatttg aaaaaaataa gatcactgca ctgattggtc cttccggctg
    20761 cggaaaatct acgtatcttc gttcgttgaa tcgaatgaat gatgggatcg ctaatacgaa
    20821 aatcactggg aaaatcatgt atcaaggcgt agatattaat gcgcctcaag tggatgttta
    20881 tgagatgcgc aaacggattg gcatggtttt tcaacgtcct aatccgttca gcaagtcgat
    20941 ttatgacaat attacatttg ctttgaaaca gcacggcgaa aaaaacaaaa agaaattaga
    21001 tgaaatcgtt gaaacaagct tgaaacaagc tgccttgtgg gaccaagtaa aagacagctt
    21061 ggacaaaagt gccttggctt tatctggcgg gcaacagcaa cgtttatgta ttgctcgtgc
    21121 gatcgcgatg aaacctgata tcttgctgct agacgagccg gcaagtgctt tggaccctat
    21181 ttcgacagga acggttgaag aaacacttgt aaacttgaaa gaagactata cgatcatcat
    21241 cgtgacgcat aacatgcaac aagcagctcg tatcagcgac tatactgcct ttttctattt
    21301 aggaaaagta atggaatatg acaaaactaa caagatattt accagaccaa aaattcaggc
    21361 aaccgaagat tatgtgtccg gtcattttgg ttaagacgga ggcctcaaca tgacaaaaga
    21421 gattatttca tctaaagatc ttcatctgta ttatggaaag aaagaagcac taaaagggat
    21481 cgatctaagc ttcaatcaag gggaaatcac tgcgatgatc ggtccttctg gttgcggaaa
    21541 atccacttat ctgcgttctt tgaaccggat gaatgacctg attccgaatg taacgatcac
    21601 cggaagtgtt ttatataaag acaaagacat ctatggtcca aaaacagatg ttgttgaact
    21661 aagaaaagaa atcggcatgg tattccagca gccaaaccca tttccttttt ctatctatga
    21721 aaatgtcatc tatggattga aattaaaagg ggaaaaagat aaaaaagtcc ttgatcaagt
    21781 agttgaagaa agcctgaagg cagcgtctgt ttgggatgat gtgaaagaca aattgcataa
    21841 aagtgcttta tctttatccg gtgggcagca gcagcgtgta tgtatcgcac gtgttttggc
    21901 agttaatccg gaaatcatct tattggatga accaacaagt gcgcttgatc ctgtttctac
    21961 tgggaaaatc gaaagtatgc tgttagaatt aagagagcgg tatacgatga tcatcgtgac
    22021 ccataatatg tctcaagctt cacgtatttc agataagacg gcattctttt tagatggtca
    22081 cttgatcgaa tacaatgata cgaagaagat attcatgaat ccagaaaaac aagagacaga
    22141 agattatatt tcaggtcgat ttggataagg aggaaacgga atgctacgta cacaatttga
    22201 agaagaattg ctgaatctcc ataatcagtt ctacgaaatg gggatgatgg tgagcagcgc
    22261 cgtgcacaag tcagttcgtg catacatcaa acacgataaa atcttagccc aagaagttat
    22321 cgaaaacgat ataaatatca ataacatgga aacacgcttg gagaagaaaa gttttgaaat
    22381 gatcgcattg caacagccag ttacaactga tttgcgtatg atcattacgg tcatgaaagc
    22441 tagctcggat ttagaacgta tggccgatca tgcggtgtct gttgctaaat ccacgattcg
    22501 cgtaaaaggg cagacgagaa taccggaaat cgaaaaagag atctccgata tgtccgatta
    22561 tgtgaaaaaa atggtggaca acgtcctagt tgcttatgtc aaaacagacg aaaaagacgc
    22621 acgtacgatc gccaatatgg atcaaagagt caatgactat ttcaatcgaa tctataatgc
    22681 aacaatcaaa aatatgcagg aaaatcctga gacagtcatc agtggaacag actacttgaa
    22741 tgttgccagt tatctagaac ggatcggaga ctatgtgaca aacatctgtg aatggatcgt
    22801 ctacttggct acagggaaaa tcactgagtt aaatacgaac cacaatgaga ttttctaaac
    22861 tgaagctgtg attatgccgt ttgtttagga aaagaggttg tgaaatcagc ggttgtgaaa
    22921 aagctgttct gcatcaagta ataagaacag tcaaacaaaa aatagctcct catatttttc
    22981 gtttggctgg acttattacc gcagatgcaa gcttttgaac accgtttatt cgggaaaggg
    23041 tttgtgacaa a
//
LOCUS       DAXLPC010000039        22730 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.039, whole genome shotgun sequence.
ACCESSION   DAXLPC010000039 DAXLPC010000000
VERSION     DAXLPC010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.039"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(445..975)
                     /locus_tag="ACF3UE_001474"
     CDS             complement(445..975)
                     /locus_tag="ACF3UE_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFD3634889.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            1080..1631
                     /locus_tag="ACF3UE_001475"
     CDS             1080..1631
                     /locus_tag="ACF3UE_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3634890.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(1784..2257)
                     /locus_tag="ACF3UE_001476"
     CDS             complement(1784..2257)
                     /locus_tag="ACF3UE_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3634891.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            2395..3867
                     /locus_tag="ACF3UE_001477"
     CDS             2395..3867
                     /locus_tag="ACF3UE_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFD3634892.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLTKAGDNA"
     gene            3864..4574
                     /locus_tag="ACF3UE_001478"
     CDS             3864..4574
                     /locus_tag="ACF3UE_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFD3634893.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            4926..5210
                     /locus_tag="ACF3UE_001479"
     CDS             4926..5210
                     /locus_tag="ACF3UE_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFD3634894.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(5491..5910)
                     /locus_tag="ACF3UE_001480"
     CDS             complement(5491..5910)
                     /locus_tag="ACF3UE_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFD3634895.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGWFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(5912..6496)
                     /locus_tag="ACF3UE_001481"
     CDS             complement(5912..6496)
                     /locus_tag="ACF3UE_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFD3634896.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLNEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFGIVNEHSKRWQGD"
     gene            complement(6543..8018)
                     /locus_tag="ACF3UE_001482"
     CDS             complement(6543..8018)
                     /locus_tag="ACF3UE_001482"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFD3634897.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDVIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGMSAKTIFDGTVPFDMKEHFVRAKFQEVKDWEKYLK"
     gene            8199..8510
                     /locus_tag="ACF3UE_001483"
     CDS             8199..8510
                     /locus_tag="ACF3UE_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634898.1"
                     /translation="MKKMEESFPKAAKVENIANILKVTFENGEVKYVKSHWTEEITDD
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(8625..10961)
                     /locus_tag="ACF3UE_001484"
     CDS             complement(8625..10961)
                     /locus_tag="ACF3UE_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFD3634899.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTDHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSD
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            11103..11771
                     /locus_tag="ACF3UE_001485"
     CDS             11103..11771
                     /locus_tag="ACF3UE_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3634900.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     HIELIITDVMMPEMDGYDLVGSLRNARFDMPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSILTIGQTKLELDTYTVVQNQHSFILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            11774..12814
                     /locus_tag="ACF3UE_001486"
     CDS             11774..12814
                     /locus_tag="ACF3UE_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3634901.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRVIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFLQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQVNGKIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAIIRLSK"
     gene            complement(13054..13935)
                     /locus_tag="ACF3UE_001487"
     CDS             complement(13054..13935)
                     /locus_tag="ACF3UE_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3634902.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITDFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            14095..14823
                     /locus_tag="ACF3UE_001488"
     CDS             14095..14823
                     /locus_tag="ACF3UE_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFD3634903.1"
                     /translation="MPTGVLINVGSVLLGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            14980..15297
                     /locus_tag="ACF3UE_001489"
     CDS             14980..15297
                     /locus_tag="ACF3UE_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3634904.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            15290..15898
                     /locus_tag="ACF3UE_001490"
     CDS             15290..15898
                     /locus_tag="ACF3UE_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFD3634905.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            15953..16744
                     /locus_tag="ACF3UE_001491"
     CDS             15953..16744
                     /locus_tag="ACF3UE_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFD3634906.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADYELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            16882..17370
                     /locus_tag="ACF3UE_001492"
     CDS             16882..17370
                     /locus_tag="ACF3UE_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFD3634907.1"
                     /translation="MKAEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            17421..18293
                     /locus_tag="ACF3UE_001493"
     CDS             17421..18293
                     /locus_tag="ACF3UE_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFD3634908.1"
                     /translation="MREKRAFYINGYAGIVGLIVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            18469..18831
                     /locus_tag="ACF3UE_001494"
     CDS             18469..18831
                     /locus_tag="ACF3UE_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFD3634909.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            18840..19592
                     /locus_tag="ACF3UE_001495"
     CDS             18840..19592
                     /locus_tag="ACF3UE_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634910.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            19606..21408
                     /locus_tag="ACF3UE_001496"
     CDS             19606..21408
                     /locus_tag="ACF3UE_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3634911.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAEKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQTTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            21684..22724
                     /locus_tag="ACF3UE_001497"
     CDS             21684..22724
                     /locus_tag="ACF3UE_001497"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFD3634912.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSLDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
BASE COUNT         7144 a         3983 c         4615 g         6988 t
ORIGIN      
        1 ctgggagcat tatttcattt tgaagtcact aatttaactg tgtgaatatg cagttgttac
       61 aatctttgat aaacggtgtt caaaagcttg catctacggt aataagccca accaaacaaa
      121 aaatatgagg agctattttt atttggctgt tcttattact tgatgcagaa cagctttttc
      181 acaacctctg attcacggtg ttccaaaagt agcttcttcg gaaataagcc gaaattttac
      241 aaaaatttga gaagcaattt ccgtaaattc cttcttattt cttgaagctg accacttctg
      301 tcacaacctc tttcttaaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac
      361 ggcaaaacat gaggaactat ttttccgttt ctttctctaa tactcaggtc agaacgctga
      421 tttcacaacc tctctttcac aaccttattt tactcgttta taattttcat cgaaatattt
      481 tccgctacgg atatcatctg gcattccatc gtatggttct tcgctaataa catcttcatt
      541 gtctatacct gcatcaccca tataagtgat agtagcaaat tcaggaacaa gtaattttgg
      601 ataagtttca tatttttcac gagctgcttc catttctgcg atatgttcgt tttggaaagt
      661 aacagtgatt tctggatgtt cttcaaccca tttagggaaa aagatcattc cgtgaagttt
      721 cttttcattt ggcataaagt ccaatgccac gtctgtccct gttggctctg tccaagtgat
      781 tttgaatacg ccgtccgtca atttaacgat atcagcttct tggtctttta cccaacggcc
      841 tttgaccatt ccgccatgga tacggtaatc aacagtatgg tcatttttgg cataccattc
      901 atattcccaa ccattatcat acgtatagat aaagtgagtt ccaataaaat cttccaattc
      961 tttaaattct ttcatgttta agcatctcct tataaattaa aacatgtaat aaactacatg
     1021 ttttcgatta ctcatttatg atagaatgga tttaaagatt tgtcaaggag ggaaaactga
     1081 tggcaagaaa aaatacactt cgatatattt tgttagggtt attaagtaag aagaagatga
     1141 caggatatga attgaatcaa tcgttcaaaa atgaaatagg agaattttgg caagcaaaac
     1201 atagtcagat ttatcctgaa cttgcaaaaa tggaagagca aggaatcatt cagcatcaag
     1261 tagagatcac aggtgaaaaa ttggaaaaga aagtttatga attaacagaa gaagggaagg
     1321 aacaattggc agagtggatt catacaccca ccaatgaact accggttaat cgagacgaat
     1381 ttgttctgaa attgtatttc gtcaaagacg tgaatgatcc ggcattagta gaaattattc
     1441 agcagcagcg tgaccttcat gaagaaaaac gacttcatct attagagcga aaaaaaacga
     1501 tctttcctac tgaaaaagaa aaacatgaaa attacggaca ctacctgatt ttagcgcatg
     1561 cgatcaatcg ggaaacagaa tatgcaaatt ggctaacaga tgtattagaa gaaagtaacc
     1621 gaaaaaaata aaaaaatatc cgaacagtga tggagaattc ctttctatat gaaagaaacg
     1681 cagatcaccg ttcggatatt cttatgttca aacaggcctt ttttcaagta tttatgtagc
     1741 atctacttat taaaaagctt ggtacttagg agattagtgg cgtttagagt tcttttaaca
     1801 gctgttcgta gtcagctttt tcatcgacag gaaggagctt gtaagttaat tcgtctgtct
     1861 cgttgtcatg aatgatgtac atcttagcat tctcttcttt gaagttaccg atttgtaaaa
     1921 tcgtatagcg ttcgtcgatc aattcgatat ctttgattgc ttttgaaaaa actttacgga
     1981 catggtgcat tttcttttgg cggatttctg ccttttctgc agcttttgac aaagtaaatc
     2041 cgtcatctaa atattttttg atcagttcta cttttatgac tgtaggtaaa cgatattttc
     2101 taggacaatt cgcatcagct tcgatcgaac gaatgaatcc cttttgttcc caatacctta
     2161 attgacgtgg agacacacct acgatatcac ttaattcact gatgccaaca accaattgat
     2221 cattttccaa caaacgttta agggaagccc caaccatttt tgtcactcct tttgtcctct
     2281 tgcttccctt aattatatcc gtattaactt atgtgtcaag taggttgaca aatagcgaat
     2341 ttaggactaa agtattctag tagtttcaga aaaaattcag aaagaaggag aaatatgagt
     2401 aacaaccaac ccgtagatat ttacggaaaa ccatataatc ggacactttt agttgttgtc
     2461 ttattaattg gtacattttg taccgttttg aatcagacct tattgacgac agcttttcct
     2521 acattgatga aagctttcga tatttcagcg tctgatgtgc aatggttaac gactggtttc
     2581 ttgctagtca acgggattat gatcccaata acagcatggc tgatcaataa attcagttca
     2641 agaaatttat atctttctgc catgacgatc tttttgatcg gaacgattac ttgctttaca
     2701 gcacctaatt ttagtacatt actaatcggt cgcttgatcc aagcttgcgg tgtgggagta
     2761 tcgatgccat tattgcaaaa tatcatgcta tctattttcc cgccagaaaa aagaggatca
     2821 gcaatgggga tgtcagggat cgttattgga cttgctcctg ctttaggccc tacattatct
     2881 ggttatatca ttgataacta ccattggcgt gacttgtttg gtatggtact gccaatcgtt
     2941 gttcttgtct tggttttagc attcttccta atgaagagcg ttattccatt gtcaaatcct
     3001 agcattgata ttttatccgc tattttatca acgattggat tcggtagttt gctttacgga
     3061 ttttctagtg taggagatga cggctgggga agcttgaaag taattggttt cttagttgtt
     3121 ggtgtgattt tcatcgcatt gttttcatgg cgtcaattac atttggaaca tccattcttg
     3181 gaacttcgcg tattcaaatc atctacattc acgattgccg ctgttttagc tggtgtaaca
     3241 aatatggcga tggtaggggc agaaatggtc gtaccattgt atattcaaaa tattcgtgga
     3301 gaatcagcat tccattctgg cttgatgttg ttgccgggtg cattgatcat gggggctatg
     3361 atgcctgtta cgggtgcgat tttcgataaa tatggcgcga aacgtttagc catcacaggg
     3421 atgttcattt tgacagccgc aactgcacca tttgctttct tgacaaaaac gactccagtt
     3481 ttatatatcg tgatccttta tgcgatccgt atgtttggga tctccatggt catgatgccg
     3541 gtaacgactt ctggtatgaa tgcattgcca aataacttga tcagtcacgg gacagcggta
     3601 aataatacat tccgtcaaat cgcaagctcg attggtacag ctattttgat cagtgtgttg
     3661 acgaatgtga caaaagcaaa tatcccaagc aaatctgtat tggataatac accattagct
     3721 tataaagatc aggcaatcaa tgccacactg tcaggttacc atgccgcgtt tatcgtagcg
     3781 atcatctttg ggatccttgg ctttattatt gcctttttat tgaagaaaaa agaacctgtt
     3841 ctaacgaaag cgggggataa tgcatgatta ttggagtttt gattgtcagc ttgcttgctt
     3901 ttgctttaac gaacgtgttc gctaaaaaaa catggcaaac ctttttatct ttgattttcg
     3961 gactaatctt cgtcgcttca ctaagtttga tcgtcgctaa tttgtccaat cactttggaa
     4021 tggaaaaagt aacggaaaca aaaacagaaa aaattgtttc cagtgctgat tcccaaggag
     4081 cagatatgct tttgtataaa gctttaggga atggaaaaga aaaagtgtat ctttaccgaa
     4141 caaatgaaaa acaagaaaaa ccaaaagcaa ctggtacgga taacgaaaca aataaagtag
     4201 aaaagacaga cggcgatgct gaaaaagtga cgaaaactac ttattgggaa tacaaaaacg
     4261 acatgtataa attctggttc aatattgctg ataacaatca cgaatatgac agccgagtga
     4321 atacattcaa aatcccagag acatgggtag aattaagtac ggaccaagca gccaagttag
     4381 ctgaattagt taagaaacag caaagtacga tggaaagtga agcaaaagct tatgttcaag
     4441 acggtatggt aaaagcaatg actgaaaatc caaaaatgag caaagcagag caagaacaac
     4501 gtacgaaagc cttagctgct gaattccaac aacaagcatt cgcaaaatta gtgaaagaag
     4561 caaaaggcga ataatatttt gaacaccgtg taggaggttg tgaaaaagct gctctgcatc
     4621 aagcagtaag aacaatcaga taaaaatagc actccatatt tttcatctga ttggggttag
     4681 tgccgtagat gcaagctttt gaacaccgtt taaggaagag gttgtgagcc tgccgtttaa
     4741 ctctgagtca caaggagcaa tttcaaaaaa cagcttctca tgtttgttga atattgtgac
     4801 ttgtgaccga ggagttggca ggagaacacc gtttattcga aaaaaggaac tgcgacaaga
     4861 cttttgtcac agttccttct tttttttgct atgctatact agatgtaaaa aataggagaa
     4921 ataaaatgag ggaaatttat tcttttgaat caaaaatcta tgcttccgaa gtcggcaagg
     4981 gcggggcata tattattttt ccgtatgata taagaaaaga attcggtgct ggaagagtta
     5041 aagtccaagc aacttttgac aatgtgccgt acgaaggcag tatcgtgaat atgggtgtga
     5101 aaaatccaga tggttcagtc tgctacatcc ttggactacg aaaagatatt cgtaaaaaca
     5161 tcggtaaaga aatcggtgat attgtagcag ttacagtgaa gcaaaaataa aagaggttgt
     5221 gacaaaagac gtgtcacaac ctcttgataa acggtgttca aaagccagtt tctcggtagt
     5281 aagtcaaatt tatgcaaaaa tgtggaaacc catgtttaca aaatttttct tactactcga
     5341 aacgaagcgg ctttatcaca acctcttgat aaacggcgtt caatcagctg tccctcggta
     5401 ttagctcaaa aacggcaaaa tatgagaagc tatttttcca tttttttctc tcatactcag
     5461 gtcataacgc tgatttcaca acctcttctt tcataatggt ttttcaccat ctttataata
     5521 aactggttct ttgatatgga aatctatttt ttccaaccaa tctaaaatct tgtaacctaa
     5581 ctcttctgac atcggaaaag aggcgttgat ttgtgcattg gagatatggt caacatggat
     5641 accggaagta atcgtacaac ttcccggaac ggcagttttg atgatcacag ctattttttc
     5701 ggctaagaca tcgtctttat ggaaccaacc atcgtggcta gggaaacgta cagtttgcat
     5761 ctctgtatca cgagaaaatg tagtgactgt tccgatatgt ggtgtatctc cgcctgttaa
     5821 agtgatcaat aagtctttac cgattacttt aacagcagct tggatcgtga aacctagttt
     5881 ggttacttca actatcgttt ctttttccat attaatcacc ctgccaacgt tttgaatgct
     5941 catttacaat tccaaattga tccaaaagtt tcattgtatg gtgattaaca agatcttgga
     6001 tcgtttgagg ctgattataa aaagcaggaa ttggtggtat gatttgcaca cctagtcgtg
     6061 ctaatttagt caagttttcc aagtgaatgg catttaatgg cgtttcacga ggaacaatga
     6121 ctaactttcg ttgctccttc attgttacat cagcagcacg tgcaataaga ttgtcgccta
     6181 aaccaacaga gatacctgcg actgttttca tacttgctgg tacgatgatc attccatcgg
     6241 tcaaaaatga tccgctggcg acagcagcac ctaaatcttt gtttgaataa tggtaatcaa
     6301 acaggctttc gaattcattt agtgataagt cggattccag ctttaagttc tgttttgccc
     6361 atggactgat gattccgtgt gtttctatca tcggatattc ttttagtttc ttcactaggt
     6421 tgatggcata aatggtgcct gaagcgccac ttacaccaat cacgattttt ttcttccgtt
     6481 gtgccaattg ttccattttc cgcactcctt tttatgatgt caaaacagtt gcagatcatt
     6541 cattatttca aatatttttc ccaatctttt acttcttgga attttgcacg tacaaaatgt
     6601 tctttcatat cgaaaggaac tgtaccgtca aagatagttt ttgcactcat cccacggaaa
     6661 cgaatagagc caggattata ttctggtaat tctgatgggt ccaatggatg gtttctcatt
     6721 cctgggatca caatgacgtc tttatctcct tggaaacgag tgttgaaagt ccaaactaca
     6781 tcgttcatgt cgaaaatatc aacatcttca tcgactaaaa tgactgtctt caattctttg
     6841 aaggctgata aagcaagaat agctgcttga cgctgaatac cttcatccgc ttcgttttct
     6901 ttacggattt gcatgatggt catcaattta ccaccacctg caggaggatt gtagacattt
     6961 actacttttc ctggaatagc tttatcgacc aaggcaagaa tacttgcttc tgtaggaata
     7021 ccggccatag atacgtgttc ttcactggga ccaatcgttg tttgcatgat tggattgtct
     7081 tttcggtgag taactgcttt gactttcact acttgtacag ctggattagc atccccagta
     7141 tagccaggaa attctggcat tgcttttcct gagttcgtgt tgatatcttc ttgcattgtt
     7201 tcatttggca tgatttctgc ttcaatgatg aattcagcac gagcaatacc cacttcatcg
     7261 actgctatac catcaacgat ttgaataggt tcgttacgca aagctcctgc acaccatagt
     7321 tcattgtagc caagtggagt ggtaggtggt tcgaaagtcg tgccaatggc aattgctgga
     7381 tctaaaccaa tattgatagt gataggcatt ggtttattca aggcttcgaa ttgtttttgg
     7441 aagtgaccaa tgtggcgtcc gccaggcatg atgtacatac cgatcgtatc tttatcttct
     7501 agaaccatac gatggatcgt tacatcgctc attgtttttt ctggatctga tcctaagact
     7561 acacccattg tgatgtatgg accagcatct tcaggagtat ttgtaggtgc aggcaaaatg
     7621 ttgcgaatat cgaagtctgc atcggtagct agatgaacga cttcttgtgc tggagcgtct
     7681 gctttgtcta ctttcacagg tttgattgga ttttctacag cgtctttcaa gaaacgacca
     7741 agtgttcgat aatcatggtg caaaatttca cctacacgtt tacgactagc cattgttccg
     7801 atgttcacac gtgtgccggg gaaacctttg atattgttga aagtcatagc tggtccttct
     7861 tgagtcggac gttttactgt accgccagca ccgatataac ggtaaacacc agataattct
     7921 gcttcaggat cgatttcaat atctgtttcg tgatattgac ctggaagtgt ttttagttct
     7981 tcgatgactt ttcttaaatc atacggttga tctgtcatga gagattcctc cttagttgtc
     8041 tttacctatc tatagtaaaa ggtgaaaaag aggaaaacaa ttcaacttgt tcggtaaagt
     8101 attctacaat ggaatggatg cgtttttttg ataatagaat aaactatgat atacttatca
     8161 ataaaagaaa gcgcatactt agtgttggag gaaggaaagt gaaaaaaatg gaggagtcat
     8221 ttcctaaagc agcaaaagtg gaaaatatag cgaatatttt gaaagttaca tttgaaaacg
     8281 gagaagtaaa atacgtgaaa tctcattgga cagaagagat aaccgatgac ttgcaatttg
     8341 gaaaaaaagg aagaggaaaa agaaaaaatc ttctcgcact ttctcgtaat atgtggattg
     8401 ggactgaagt aacgattgaa gcagatggaa cagtattcat aaatggaaaa gacaggtata
     8461 cgccagaaga gttgtggtac aaaggaaaga aaagtatacc agaattataa aaaataatta
     8521 aaaaaaacag cgcgaaacaa ggaacatatt acttcctcgt ttcttgctgt tttctactat
     8581 ttcagcgctc ttatgactca aatctaaatg tggttgtcac aaccttattc tgcacgcaaa
     8641 gcgatagcgg cgtctttttt cgctgccatt cgtgcaggaa gatgaccgcc aagcatcgtc
     8701 aatatagtag agacgatcac tagaataatc gcatggacag gatttagttg agcaacattt
     8761 tttagatccg tcatgttgta taagatgcta ttgataggga atgtagctag ccatgcaata
     8821 aacacaccta atatcccaga agaaatacct aaaatacacg tttctgcgtc aaatacgcga
     8881 gtgatgtctt ttttacgtgc acctaaagct tttagtacac cgatttcttt tgtccgttca
     8941 atcacagatg tataagtaat gatactgatc atgatcatac ttgttactaa agagatccct
     9001 gcaaaagcaa taaggacata agtgatagca tccatcaatc cgccagtcag ttcagtcatc
     9061 gttccagcta aatcagtata aatgatttta tcttcatctg atttgccttt attgtaatca
     9121 tctagataat ccaagatctt ttctttgtct tcaaaattgt tcggataaat catgatactt
     9181 gaaggcaagc tgtctccacc taaataacta agcaatgttt gtttggcatt ttcgtcaact
     9241 ttttcagtag ttaagacatt tacatcactg tctctttgag ctttgacgat ttctgattct
     9301 ttgttttcgt tgacgatttg agtcgttaat tgatcgctat aagcgattcc tggagataag
     9361 agattcattg tagaagaaga tttcacgcgt aggatccccg agatcttcaa ttcatcagaa
     9421 gcattctgat acatcgcatc ataatctgta ttagggataa aattcccagt tggaagtttt
     9481 gtatagtaag tattgttgtt tactaatttg aatgttgtac caacgatatc atcaaaatca
     9541 agtttttcgt cttctttcac atcaaatcca agattcttca atgcgttgat attagtatta
     9601 ttattgccgt ctacgatcag cacgacatct gttgctgagg ctggataact tccggcaagt
     9661 aaagaataat tgtcttttaa aaagttttct ttgctagtgt caagctgtgt agggaaactt
     9721 gacactccca cacctgtcat tgctgacatc gtactagata aagaaagaga ttccgtatca
     9781 ggattttgat tcgagaagct gacaggctgt actttgccat ttacatcacg taaaagattg
     9841 attcctgtag tacgggtaaa tccgatatta ttacttaagt taggatcgat gtctgttacg
     9901 taatcgacgt atgtttgatc aatcttattc gtgtgctgtg ctttatcttc ttcgctgact
     9961 tttgcagtaa tcgttttgct gtctggataa tccgctttgc ttgcacccaa tccggcatcg
    10021 tcacgagtct ggttagtcgt taccttagaa atagtaatcg gaaatttcgc catcgtttca
    10081 gcttgcgtgt tatcgatttg tttttggaat ccagaagaaa gggacagaac gatcgcgatt
    10141 ccgatgatcc caatactgga agcaaaggag gtcaagaaag tacgtccttt ttttgttcgg
    10201 atattgttga aggaaagctt caacgctgtc caaaaactca tctttgttct gcgtaagtta
    10261 aattgatcat cttttggccg ttcgatgtga ggatgggaat ctgttaagat cttaccatca
    10321 gaaaattcaa tgatccgatc tgcgtattga tgggccagtt caggattatg tgtgaccatg
    10381 atcactaatt tttctttcga taactcttgg atcaattcca tgatctggat acttgtttct
    10441 gtatctaacg ctccggttgg ttcatcgcac aaaaggatat ctgggtcatt ggctagtgct
    10501 cgagcgatgg ccactcgctg catttgtcca ccagataact gatttggctt tttatgcata
    10561 tgatctgtca agccgacccg gtgcaatgca tcttctgccc gttttcgttt ttcgtcttta
    10621 gaaacaccac ttaatgtcat cccaagctca acgttttcaa taatgcctag atgaccaatc
    10681 aagttgtaac tttgaaaaat gaaaccgata gagttgtttc ggtaggcatc ccagtcactg
    10741 tccttaaagt ctttagtaga ctttccgttg attaccatat caccggaatc ataattatct
    10801 agtccaccaa tcacattcag catagtcgtt ttaccagaac cactaggacc taaaatcgct
    10861 acgaattctt tttgtctgaa agcgacagac acaccatcca atgctttggt ggtggtttcg
    10921 ccgactttat aatatttttt tatatctttt aattgaagca taatcaccct tctcccgtat
    10981 tgaaatattc ggtatactaa taagtatatc agaacaatga tcgtagtata cgaaataaat
    11041 gttaactgaa gatgaactac aagaaaaaat ctagaaattt ttcaaaaaac agagggagat
    11101 caatgaatcg tattttagta gtagaagatg atccgcaatt acagttgctt taccgttctg
    11161 tgttggaacg agcgggcttt tcagtcatca ccgcactgaa tggagaggat gcgctgaaaa
    11221 aactagaagc gacacatata gaattgatca ttacagatgt catgatgcct gaaatggatg
    11281 gctatgactt ggtaggatca ttacgtaacg ccagattcga catgccagtt ctgatgatta
    11341 cagcaaaggc tgatttcgag gacaagaaac gtggattcaa attaggtgca gatgattata
    11401 tgacaaaacc catcgatgtc aatgaaatga tcctgcgtgt ggaagcattg cttcgacgtt
    11461 caaaaatcaa ttacagcagt atcttgacga ttgggcaaac aaaattagag ctggatactt
    11521 atacagtggt acaaaatcag cattctttta ttctgcctca aaaagaattt ctgcttctgt
    11581 ataaattact gtcttatcca aacaagattt tcactcgcca gcagttgatg gacgatattt
    11641 ggggattaga cacgaataca gaagaacgaa cgatcgatgt acatatcaaa cgtttaagga
    11701 cccgttttga aaagacagaa gattttcaaa tcatcacagt acggggacta ggctataagg
    11761 cggttattta aagatgaaaa agaagctatt ttcacaatta tggatctatt ttgctagtat
    11821 cgtatttatt tcgatcttag taacactgct gtgttttctt ggttttattt tcttattgtc
    11881 tcgacattct atctcgcctg ctgaatcggc tggaaaacca acgttatacc cgttattcgt
    11941 ctttgcgggg ttcagtatgg tcgtgggtac aggaatatcg atttttgttg ggcggcgtat
    12001 cctgcatcca atcagtgcgc tagggacaaa tatgagtctg gtagcaacgg gagatttttc
    12061 gattcgaatg gatgaacagc agaaagtagc agaagtacag caactgtata aagatttcaa
    12121 cgttatggtc caagaactca atagtatcga gacactgagg aatgactttg tgtccagtgt
    12181 atcccatgaa ttcaaaacac cactagcaac aatccaagga tatgttcaat tgttacaagc
    12241 cccaaatctt tctgacgaag aacgccaaat atttttatat cgggtcatcg aaagtatcac
    12301 gcagctttca caattaacag agaacatttt aaaattaaac aaactggaaa accagcgtat
    12361 ccaactggaa aagaaagagt atcgattaga tgaacaaatc agagaagtaa tcgttttttt
    12421 gcagcctaaa tgggaaaaag aacagctaga attggatatc gaacttgctg cagtaaacta
    12481 tacaggtaat gaagagtttt tgtaccaagt gtggctgaat atcatggata acgccataaa
    12541 gtacaatcaa gtcaatggaa agattcatat caaattattt gagacagcca cagagatcgt
    12601 actggaagtg accgattcag gtgtaggaat gaatgaagag acccgagatc gaatgtttga
    12661 aaaattttat caaggagata caagccgtca gatttctggg aatggactag ggctttcact
    12721 ggtcaaaaaa attctagaac tacatgatgg acgtatcgat tatagcagta tcgaaggagt
    12781 agggacgaca gcaataatac gtttaagcaa ataataggaa aaaagaacaa aatacctaaa
    12841 aattctagtg aaggttttta gggattttta gacgtttttt tgtgattagc gaattgctct
    12901 taatgttctt ccggcataaa atcgctgatc ttctattgaa atacgagaaa cgttagatgt
    12961 gtcattgaat caatggcacg atgtaagaaa gagagcgaaa gtcatgcgtc gctctctttt
    13021 ttggggtgga tagatggaca gaaaatgtag ggcttagttt tcttcttgat ttaaatactc
    13081 ccaaaatgta tctgaagcca aagaatgctc accgacttta cgagtaaatg caagataact
    13141 ctctgttgtt ggagaaatag ggagaatcac agtattttct tttaatagat tcttgactgt
    13201 tttttccata acaatagcaa tccccatgtc atttgcaatc atattgatga tcaagtcgat
    13261 tcttgctcct ttataagaga tttttggttc aaatccagct tcgcgacaca gatctagtac
    13321 aggttgatac aagttcgtag tggggccaag tagcaaaaag ttctcctttt tcagttcgct
    13381 tagatccaat ttctttttac tagctaaagg atgattttta ggtagaactg ctacaaaatc
    13441 gtctgtttca gtaggcaacc actcaatcga actcggcggg gcctggaaac ttctagcaaa
    13501 gtggatcgtg tcactatgtt cattggcgtc attgtaagtt aattcgacac tttccacttc
    13561 tttcaactgg actgtaaatt caggatggcg tttcaaaaag tcggtgattt tggaaaaacc
    13621 tttataattg atcattgtcg gtatcgttaa gatatttaat gaaagattgt tgtctttcgt
    13681 ataggtttca agcacttctt gcatagcatg gtattgttct acgacatttt ttacatatgg
    13741 gagcaataag cttccagctt cggtcaattc gatttttcta tgggcgcgtt cgaataattt
    13801 gacgtctaat tctgtttcta acgaaagaat ctgtttagaa atatttcctt gggtggtgaa
    13861 ttgtcgatca gcagttttgg tgaaattcat tgtttcggct aaatcaagaa aaacttcgaa
    13921 tttatggata tccatcatat tcctcctact tattccaata aagaatactt taacacaaaa
    13981 aatgaattgg tgtaatcttc tctgtctgtt acaatctttc ttgcagcgaa agcaataatt
    14041 acagaaattt ttctgatttt tttcgcttcg tagaaaaaga gaggagtttt tttgatgcca
    14101 actggagttt tgatcaatgt aggttccgtt ttgcttggcg gactaattgg cggattagta
    14161 ggaaataaat taagtgaaca ttttaaagca cagctgacga tggtttttgg tgtgtgttcg
    14221 atggggatgg gaatctattc cattgcgccg atgaaaaata tgccggctgt tatttttgct
    14281 ttagtgatag gaacagcgat tggtctgatt gttcatttag gtaatgggat aaataagggg
    14341 gctgcgctga tgcaagtacc tatttctaaa atcttcccta gtgaaaagct tggtatgacc
    14401 cacgatgaat ttatcagtac attagtgacg gtcattgttc tattttgtgc aagtggtacg
    14461 gggatctatg gaagtttaga ttctggaatg acaggagaca gtacgatttt gatttctaaa
    14521 tctgtccttg attttttcac agcagctatt tttgcgtgta atttagggta tgtcgtttct
    14581 gtgatagcaa ttccccaatt cattattttt tatattttgt tcttattggc aaaatttatt
    14641 tatccattga ctacaccaga catgatctta gattttaaag cttgcggcgg attcttgatg
    14701 gtcgctaccg gttttagaat gatcaacgtg aaaatgttcc cagtagctga catgatacct
    14761 gcaatgatcg ttatcatgcc actgagctgg atgtggacaa attggattat gccactgtta
    14821 taataaaaat caaagagaag ccattttttt gctgactaaa aaggatcaaa tcttttagtc
    14881 agtttttttg tatttgacaa actgattttg aaactatatt atatgttgta taatatagat
    14941 tgaaataaaa tattacactt gagaatagaa ggtgacgtaa tgcacatcca gattccaact
    15001 gttcttcttg atggtactgt gttagcagca ttaagcaagg aagatatgta tgggtatgcc
    15061 ttaacaaaaa tcgtacaaga aagtctctct gtcagtgaat ctacactata tccggttttg
    15121 agaagattga aaaaagaagg atatcttgag acctatgatg aaccttttga aggcagaaac
    15181 cgtcgatatt actcgttgac accaatggga agtcgtcatt tagaagaaat tattgatgaa
    15241 tggattgttt ttcgagattc tttagaccgg ttattggagg agagcacaaa tgaatgaata
    15301 tttgaatgaa gttgtggatc atcttcaaga aattcctgaa gacgatcgtt ttgatttgat
    15361 ccagtattat gaggaatatt ttttagattc tggaaaaaca ttagatcaga tcattgatga
    15421 atatggtaca ccaaagcagt ttgccttaaa attaaaaatc agttactttt cagaagaaga
    15481 acaagcagaa aacgagttag tgaaaaatcc aaaaagacaa attcgcctga tttggttaat
    15541 cattatcggt ttatttgctt ctcctgtcct cattccacta gcactggggt ttatattggt
    15601 tattggggga ctattggttg ctttactagc gctcattttt agtatctatg ttttatgtat
    15661 cagtatctta ggtgttggcc tattcatgat catatcagga ataagtgtgt ttggacaatc
    15721 gattctgagt ggattattct ttatcggtgt cggtctgttc gccacaggaa gcgcagtatt
    15781 tatttcgcca ctgttgctga aaggaacaaa agggcttttt tatgtcatga tgaactttgt
    15841 taaatggatg ggacgacgtt ttattacaaa aagagatctg cattcagcgg gcgtttgaag
    15901 gaggacacat aaattgagat tgaaacattt tttgattacc ggtattggtc tgatgcttac
    15961 tggtggcctc ctagcaggtg caacttatac attaggcgct caaaagagtc tgacttggga
    16021 taatggtcct cggttgatcg atatggttac tgagacaaaa aaaatcaagg atgcaaacaa
    16081 aatcgtcatc catgcagaaa atcaaacagt ttcggtcata cgcggattgg attttgagat
    16141 aaaaacgact tatgataaga cagaaaagcc agaaataaag gagaaaaatg gcgtgttgac
    16201 tgtgaatgca gtcaaaaaat caacaggtgc aatcattagt ttagaagaca caagtgcaca
    16261 aatcactatt gttgtccctg cagattatga attatctgaa ttgacaatcg aagggaataa
    16321 tagtgcaatt gatatcaacg aagtatcaat caaaaaagtg aatactaaga cacatgatgg
    16381 ctgggtatcg ttcaatgaat ttacaggagg aacaataact gcgaaagatg aattaggctc
    16441 acttcgacta gatgaggcca atgtggataa cttgatcgtc acaggtgaaa acagcaactt
    16501 ccatctagaa gacagtttga tcagcaaaga aggaaaagtc atcctaaacg gtggtaattt
    16561 atctttgcat gagatggaaa acagtggcta tactatccaa acgtctggtg aatcttatat
    16621 tgaaaaagac taccagccaa taacaaatac tttgttagaa caaggacaga aaaagctaaa
    16681 gatcactgct aaagacacat cgatcaatat tacgacggat caagaggaca atgaaacaga
    16741 ttgatcctgt actcaactag atattttaag aaaaaacagc aaagatcctt ccaatctttg
    16801 ctgtttttca tcgcttaacg cacataacta tagtaaaata agaaagaaaa tatctataaa
    16861 gaaaacaggg tgaaaaagta tatgaaggca gaagaaggtc aaagagaaaa gttaaagaca
    16921 gaaatggaaa gattacatac ttatatcact caactaagcc aaaccttcta tgatccagac
    16981 aaagaaaaag tgatggttaa ttacccgaac aattcagaag gtcgccaatt agagcaagtg
    17041 taccatgaag ttttcaaaca tttattgacg gtgaagaaag agctggatta ttattcttta
    17101 ccgattatcg atacaggaat attgaagtat gatgggaaga aggaacgatt tatctttaaa
    17161 tctgttcggg aagatttgcc tctttcagca gggatggatc tagaggtctt ggtagaagac
    17221 tattttacag aagaaaagca ctgggttcga acaaaattgg attatttacc gcaggcagcc
    17281 ggagggacac aggcaagcgg ttggtacatc actgaagaca aagagttaga actagaaggt
    17341 gtaatggcgc gtattcgaaa aaaaaattaa aaaagtaaca ttagatattt attgaaggat
    17401 aaaggagcgc aggaagtagc atgagagaaa aaagagcatt ttatatcaat ggttatgcag
    17461 ggattgtcgg attgatcgta ttagctttag ttggattgtt tttcttctat ttaggcatgt
    17521 ggcaagcgaa agtttgggca ctttttttaa gtatttttct ttggttgatc acgttattgt
    17581 tgttaagttc ggcaactgta gtcagtccta atcaagcaaa agtaattttg ttttttggac
    17641 aatatttagg tacgattcga gaaaatggct ttttccttac gatacctttg gcacaaaaaa
    17701 tgactgtttc gttgaaagtt cggaatttca atagttctgt tttaaaagtc aatgatttgg
    17761 atggaaaccc catcgaaatc tcagcagtag tagtctttaa agtcgttgat acagcaaagg
    17821 cattattcga tgtagcgtat tatcaagatt ttgtagaaat ccaaagtgag acagccattc
    17881 ggcatatcgc tagccaatac ccgtatgata cattcaatga gaatgatttg acgcttcgag
    17941 gaaacacgac ggcagtgtct gacgagttgc aaaaagaact gcaagagcgt ttagcagtag
    18001 caggtgtcga agtaatcgaa acacgcttga accatttagc ctatgcaaca gaaatcgcta
    18061 gtgccatgct ccaacgtcaa caagcaaaag ccattttgtc tgctcgacaa accattgttg
    18121 aaggagctgt cacaatcact caaatggcct tagagcaaat cgaagatgga caagaaatca
    18181 atttcaccga tgatcggaaa gtccaattga tcaataattt acttgtctca atcattacag
    18241 acaaaggaac gcaacctgtt atcaatacag gcgacatgaa agaccgtaag tgacatactt
    18301 tttgtaagat aggaagaagg agtttaggac ggattattgt cttgaactct ttttttagtt
    18361 gttttaaaga aaatgacaaa attgaaagaa gaatgatagt tgattcgaag gcagaattgt
    18421 tcgctttttt ctataatcag tatataaagt aagagagaag gggaaaaagt gaaaaaactt
    18481 ctgatcggtc tacttgtttt catcgttgtg gtacttgcag gggtgaaaat cgcagattac
    18541 gtagttatgg gtggagaaga atactatgta caaattacga cagatggtac aaaaacagtt
    18601 tcaaaatcag actctggaca agaaacagtc aactatagat atatcctgcc tggctatacg
    18661 aaagagggta aggaaaaaga actggacttc aagggacaat tgactcgacc gcttcgtaaa
    18721 ggagcatatt taaaaatcac ctggaacaaa aataaaggtg tcacttcgta tgaagaagtc
    18781 gaaaaaaaag acgtgccgaa aacagcactg gaaaaactaa ttaaagggta gggaaagaaa
    18841 tgaacaaaat agtcgaagta cagaatgtaa caaaagtata cggaaaaaac aatgagaaaa
    18901 agacgcaagc attaagcggc atcagcttcg atgtagaaaa aggcgaattt attgggatca
    18961 tgggcgcttc tggttctggt aaatcgacac ttttgaatat tttatccaca ttagataaac
    19021 caacagatgg gcatatccga atcaatcaaa aagatgtgac cacattaaaa ggaaatcaac
    19081 tagcagattt tcgtgcgaat gagattggct ttattttcca agactttaat ttattagaaa
    19141 gcttgacagc acaagaaaat atcgctgttc ctctttcttt acaaggcgtc agaccaaaag
    19201 aaatcaagca acgtgtccaa aaaattgcag aacgtttatc catctctcat attttggaaa
    19261 gctatccttc tgagatttcc ggtggacaaa aacaacgggt cgccgccgca cgtgcattga
    19321 tcacacaacc aacgattcta ttaggggatg agcctacagg tgcgctggat tccaaaagtg
    19381 cccgggatct tttagatacg atggacgaat tgaatacaaa agatcatgta tcgattcttc
    19441 ttgtgacgca tgatccgttt tctgcaagtt attgccaacg tattttattc atcaaggatg
    19501 gcggtatcca tcaagaagtg aaacgtggag atcaaagccg tgattccttc tatcgagaaa
    19561 tactatctat tcttggaaac ttggaacagt agggggagat tgactatgct ttggaaatta
    19621 tcacttactg ggatcaagag ccgtttaaga gactacttgg tgttattctc aggattagtt
    19681 atggcatctg ctatttttta catgtttgaa tcaatggcaa gcaacgaagc ttttttgaaa
    19741 agtaatacga tcgttgcggc tacagttatc attttccgat tcggttctgt tttactaggg
    19801 atcatcacat tcgtttatat tttatatgca aattcctttt tgatgacgat gcggcaaaaa
    19861 gactatgcaa tgtttatgat gctaggagca aaaggcagaa aaatcgcaca gatgattttt
    19921 tctgaaacat tcttagtagg gatcgcagct actttagtgg gttcagctgt cggtgtagga
    19981 ttgacaagta tcgtccaccg attattagtg gatcagttag atctcaatat ttcgcatttt
    20041 acacctttta gtattcacgg gttgttgatc actgttttgt tttttgctgt tttgttttta
    20101 ttagctgctg ttgtcaatgc tttttcgatt gtcaaaaaac cgattttagc attgattcgt
    20161 gcggatcaga caccaacaag aatcaagcag cataaattct tgtttttcct tgaagtagta
    20221 ctgggaattg cttttctagg ctgcggttac tatatgatga aacacgtggg gacctatcaa
    20281 gtctttggta taggagtagc cttagttacg atcgtattag gaacttattt cattttccat
    20341 tctgtgatca ttttcttttt atcattacta aagaaatcag aacagatttc attgaaaaaa
    20401 ttgaacaatt tcacattgtc acagttaaac tttcgtattc gtgaatatac acaaatgctc
    20461 tcaatggtcg ctatgctgtt tgccttggca ctgggcgctt tgacggtagg attaggtttt
    20521 aaaaatgaaa ttgcagactt gacagaaaac aattctggat atgatctagt gatgaataat
    20581 cctcgggcag aagatcagca aaaaatcaaa gaactttcac caacactttc tgcttcttat
    20641 actcaaaaag aagatgcggg aacgatttac tataatgcaa gtgaatttgc ggctcaacca
    20701 ttgatcatga taaaacatga agatggaaca ccgccgaaga tcacgaaaga aaaagttcct
    20761 gctgaaaaaa tgaatgaact gactgtacaa gaggaacttc gaagctatga attgccggaa
    20821 cagcaagaaa aagaaatcaa ggtagtcagt caatcagaat ttgatcaact gaacttgcca
    20881 caaaccactt tacagctagt tcaggtaaaa gacttccaag caaacctgaa accaatcgaa
    20941 acacttgttg ctcaaaataa aatgaacaat ccatctttgc aaaaagtaga gtacagcaac
    21001 cagaaatatg aaatgtatga agtgtataat ggtctattct ctggttttga atttatggga
    21061 ttcttcctag gtttagcttt cttgaccatg cttgctagct gtttgatgtt caagatcttg
    21121 tcaggaagca agagtgacat tgctcgttat gaaatgcttg aaaagatagg aacacgacgc
    21181 gggttgctta aacaatcgat ccgtagagaa gtaggcgtgt tattcttagc accaggaatc
    21241 ttaggtgtag tccatgtctt attcggatta caaatgtttg gtctattcat gcaaaatcca
    21301 tacaaagata tttgggttcc gtttacgatc ttcttcgtat tgtatttcat ctactatgta
    21361 ctgacgacat ggttatatac tggaatcgta ttgaaaaaga gattgtgaaa aagctgtcct
    21421 gcatcaagta ataagaacag ccaagcaaaa atagctcctc atatttttcg tttgattggg
    21481 cttattaccg cagatgcaag cttttgaaca ccgtttgttc ggaaaaagag gttgtgacaa
    21541 tacttttgtc acaacctttt ttcgcggtct tttattagaa tatagtaaat tttttctcgt
    21601 tactcacgga ataagctgtt aagaaaacgg tttctatgta tactggaatc agtgcaaatg
    21661 aaagaaaaga gggtgcaagg aacatggaaa tcaatgaaca aaattttggc gaaaactatc
    21721 acttgattac tatcacgaat caaaatggga catctttgtc tgtcagtgat cttggggcac
    21781 gggttgttca ttttcaaaca ataatcgata atgaaaaacg agagttgatc ttaggttttg
    21841 atgaagcaaa agaatatcta gaaaaagacc cttatatcgg tgcttcaatc ggacgtatgg
    21901 ctggacggat cacgaatggc acattcaaat tagatgatga aacgttcgaa gtaaaaacag
    21961 acccggacac tggtcattgt ttacatggtg gtgcacctag ctttgaagcc aagcagtggc
    22021 attatacagt catcaatggt gaaaacgaag catcggttat tttctatcag actagcccag
    22081 acatggaaaa cggatttcct ggaactttag atgtagaagt acggtatacg ctgacgaacg
    22141 atgatacatg gcgagtgacg gtccaaggga tcagtgaccg caaaacagta ttcaatccta
    22201 caaatcatgt ctatttcaat ttaaccggtg atccagcaca gtcaatcgac gaacatatac
    22261 tttggttgaa tagccgatta tttgctacgc tcaataaaga tacaacgcct acaggagaag
    22321 tagtttcagt aagtggcaca gcatttgact tccaacgtcc taaaaaatta ggtgaggtct
    22381 ttgccagtga ttttcgccaa tcaatgatag tgggcggtat cgatcatcca tttttgttga
    22441 aaaaacaatc tggtttacta aatgctgcgg aattgacaag cctagatgaa aaagtatcga
    22501 tccaagtaaa aacagatgct tcaggaatcg tgatttttac agcaaatttt ggagaagatg
    22561 gaccggaaat gcgcgggaat aaattagtaa atcatggcgg tatcacattt gagactcaag
    22621 aactgccagg agcggagcga cttgaaagtt ttggagatgt cactctggaa cctaatcaag
    22681 tacgcgagtt tgtaacggaa tacaaaataa atataaagaa atagaataaa
//
LOCUS       DAXLPC010000040        22195 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.040, whole genome shotgun sequence.
ACCESSION   DAXLPC010000040 DAXLPC010000000
VERSION     DAXLPC010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.040"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            368..922
                     /locus_tag="ACF3UE_001498"
     CDS             368..922
                     /locus_tag="ACF3UE_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3634913.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(1095..1568)
                     /locus_tag="ACF3UE_001499"
     CDS             complement(1095..1568)
                     /locus_tag="ACF3UE_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3634914.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1580..2527
                     /locus_tag="ACF3UE_001500"
                     /pseudo
     CDS             1580..2527
                     /locus_tag="ACF3UE_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
     gene            2798..3233
                     /locus_tag="ACF3UE_001501"
                     /pseudo
     CDS             2798..3233
                     /locus_tag="ACF3UE_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345965.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
     gene            3249..4082
                     /locus_tag="ACF3UE_001502"
     CDS             3249..4082
                     /locus_tag="ACF3UE_001502"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3634915.1"
                     /translation="MLYFSAIDNADFVFSDPFTAEVLSGIEEQAKNHGYFVLVHNVNS
                     AEDVKTIQRNWRFEGFIVVGVRVKEFLELNNVFDGPVVYIDTHLSKETLRELEQQMNR
                     LFVNTNDYQASTLAVEHLIHYGHEKIAFLSFDYIVGEPSVIQERHQAYIDTLKKYHLT
                     FKSHWIYNNSEFERIYQELAEFTAIVVTGDYLAAKLVKFLKNKNKRVMEQLSIIGFDD
                     ITFAELMDPALTTIRLNPGNKGAIAFHQLIGLAKQEEIKNQVLLLEGELISRDSVHKI
                     K"
     gene            4327..5352
                     /locus_tag="ACF3UE_001503"
     CDS             4327..5352
                     /locus_tag="ACF3UE_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3634916.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5490..5615
                     /locus_tag="ACF3UE_001504"
     CDS             5490..5615
                     /locus_tag="ACF3UE_001504"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634917.1"
                     /translation="MKHFKKIALTGIAVLTGTLLAACGGGDSNSKDGQVTLSYAS"
     gene            5640..6755
                     /locus_tag="ACF3UE_001505"
                     /pseudo
     CDS             5640..6755
                     /locus_tag="ACF3UE_001505"
                     /inference="COORDINATES: protein motif:HMM:NF024808.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
     gene            6838..7734
                     /locus_tag="ACF3UE_001506"
                     /pseudo
     CDS             6838..7734
                     /locus_tag="ACF3UE_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338086.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
     gene            7750..8574
                     /locus_tag="ACF3UE_001507"
     CDS             7750..8574
                     /locus_tag="ACF3UE_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3634918.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLALGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8606..9916
                     /locus_tag="ACF3UE_001508"
     CDS             8606..9916
                     /locus_tag="ACF3UE_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HFD3634919.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            10064..11323
                     /locus_tag="ACF3UE_001509"
     CDS             10064..11323
                     /locus_tag="ACF3UE_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3634920.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11333..12205
                     /locus_tag="ACF3UE_001510"
     CDS             11333..12205
                     /locus_tag="ACF3UE_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3634921.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            12217..13047
                     /locus_tag="ACF3UE_001511"
     CDS             12217..13047
                     /locus_tag="ACF3UE_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3634922.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            13087..15270
                     /locus_tag="ACF3UE_001512"
     CDS             13087..15270
                     /locus_tag="ACF3UE_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFD3634923.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15331..16551
                     /locus_tag="ACF3UE_001513"
     CDS             15331..16551
                     /locus_tag="ACF3UE_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFD3634924.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16548..18008
                     /gene="gtfA"
                     /locus_tag="ACF3UE_001514"
     CDS             16548..18008
                     /gene="gtfA"
                     /locus_tag="ACF3UE_001514"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HFD3634925.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            18085..19191
                     /locus_tag="ACF3UE_001515"
                     /pseudo
     CDS             18085..19191
                     /locus_tag="ACF3UE_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19513..19722
                     /locus_tag="ACF3UE_001516"
     CDS             19513..19722
                     /locus_tag="ACF3UE_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFD3634926.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19715..19864
                     /locus_tag="ACF3UE_001517"
     CDS             19715..19864
                     /locus_tag="ACF3UE_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HFD3634927.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            20018..20683
                     /locus_tag="ACF3UE_001518"
     CDS             20018..20683
                     /locus_tag="ACF3UE_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3634928.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(20967..22052)
                     /gene="xerS"
                     /locus_tag="ACF3UE_001519"
     CDS             complement(20967..22052)
                     /gene="xerS"
                     /locus_tag="ACF3UE_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFD3634929.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT         7553 a         3330 c         4254 g         7058 t
ORIGIN      
        1 aatgaaaagt ttggtagcac ggttattcat atgctaattt atttcacttt atagtaaggg
       61 gagttcttag tatattgttc aaacttaaat ttcatataat ttaattatgt aaattagcta
      121 ttctaagaac ttctacggat aactgcccgt ctaaaattta aataagagct tagaatcttc
      181 atataagtaa ggttaatttt tttgtacaaa aaagtcggaa tattctgagt tactgaaatg
      241 atataaaatc ataaactaaa tcccttgatt ttattgactt tcaaaagttt atatatataa
      301 gttaatgatt atggtaaaat atatacataa tcattaactc agaatatttt taagaaggga
      361 aacaatagtg agctataatg tacaaccgtt aaggacaaat gaagagatac aagattttca
      421 gttttggcta agaagaacaa gtaatccgga aagagatagt tttttatttt tgtttggaat
      481 caataatggg ttacgtatgt cagatattat aggattaaaa gttggagata tacgaggcaa
      541 aagtaagcct attattgttg aacataaaac aggtaagcga aaaccgattt ttatagataa
      601 tttgagagaa gaaattttat tatatactga aggtaaagaa gaaaatgatt ggttatttcc
      661 gagtcggcaa caaggtcgac atataacaag ggatcgtgtc tatcagatat atgcagatat
      721 agcagaaaaa ttaggacgag atgatatagg aacacataca ttaagaaaaa cttttgggta
      781 tcactactac aagaaaacta gagacattgc taccttaatg tttattttta atcatagctc
      841 gcaagcaatt acaaaaaggt acattggtat aactgaagat gaaataggag catcacttcg
      901 tggatttaaa ctaggtgtat aatttaaaaa tttttataaa cagtaaagac aaagattaaa
      961 agctattttt atctagaacg attttatttc ataaagttcg cggaataaaa gctggggtta
     1021 ctggtacttg gtataggttc gtgttatata aactaagtaa ttaaataaca tttttaggtt
     1081 ggaaaaggat gaaattaaaa aaagagaatc aatacggtct caaaaacgca aacgctgcgg
     1141 aataagaaaa atactgataa ctcaacgttt agcagactat ctaataggga tagtctgctt
     1201 ttttcgtttt tgaccatact tttgaccttc tgcaaacttc cttgcttttc ctctgtagaa
     1261 ctcatgaaat ctgcaaaacg aattgccgtt tcctctgtct gctttttcgc gatatgggtg
     1321 tatatatcat ccatagtggt tttaatatct gtatgtccaa gtcgaacata cacttctttg
     1381 acagacgcac cagattcaaa gagcagacta caatgggtat gacgaaaacc atgaagtgtg
     1441 atatgtttta agttattctc tttaatgatg attttcaaat tgtgatttac atagtctaaa
     1501 taaaggggct tattttcttc tgatgaaaac aaaagttgtt caccatcttt tataggtttg
     1561 attctcattt ttagatatta tgcccgcacg tattcatcac atttctattg tgaatcgctt
     1621 tattcgaccg acatttgact tttatcataa tatactcggt ttaaaattac taatgaaaac
     1681 aattaatcaa gacgatcata ccatgtatca cctgtttttt tcagataatc accaccgtgt
     1741 gggaactgaa ctgacttttt ttgaagtaca agaagggaac aaccagtttt ttggaaccaa
     1801 tacgattgaa cgaacgatac taaaagttcc ttccgaagca tcattgcatt tttgggaaat
     1861 atattttgaa acacaaggcg tttgccatta tggaatcgaa tcattttctg gacgacctat
     1921 cttacgtttt gaagggccag atgcaacacg attagcttta gttcccttac gcgaatttga
     1981 agatattgat gattatttcc cgtatgtcac agaccagatc cctacagagc atgccatttt
     2041 aggaattgat gccattcaac tacgcgtaca atattccgat gcgactgaac gagagttatt
     2101 gtcggtaggc tggtagcaca aagaatacgt cagtttcttt tcgggtcatc aacgagtgac
     2161 aatcttagaa aatcaagaca ctcagttcta tcaagaagtt cagattattc aagatcgtga
     2221 gaatccagtt gccattgaag ggattggtag cgtccatcat gttgcgtttg gcgtagaaaa
     2281 taaatctgat ttacaacgca tcgacaaaca attacaagag cgcaatttta taaattcagg
     2341 aataaaagat cgtgaatttt ttgtatcact ttattatcgt gacccaaatc aattattgat
     2401 tgaaattgct acaggggaag gaaacctaga tgcaaaagcg tatgaaaatc aaagtccacg
     2461 ctttgaagaa attcctttat ttttaccgca gtacttaaat ttcattcgtg aacaagtgga
     2521 gcaataatta gctaatcaaa tccatgacga agagtaagag gttgactcat aagtcaaaaa
     2581 ataaagaaaa acgcatcaaa tccattctaa agaatgttga tttgatgcgg ttcctatttt
     2641 tataaactat cattttcgac taataaaact acttatgagt cagcctctct ttttttcttg
     2701 atttttatac ctctttctag gtaaactaaa catctgccaa aaataccgtg tctcattgaa
     2761 acattctcaa ctatttcaaa ataaagggga gtaccaaatg aacgagtata ttgaaattat
     2821 ccacgcaaga gaaacaactt aaaaatgtca gtctcaaaat tcccaaaaat aaaattagta
     2881 tttttaccag cgtatctggt tcaggaaaat catcgattgt ttttgatact attacccaag
     2941 aagctggtcg tcaactgaat gacacctatg atagttttac ccgtttattt ttacctaaat
     3001 acagtcgtcc agaggttgat gagattgata atctttctac ggcgattgtg gtcaatcaaa
     3061 agaagattgg tggcagtgcg cgctcaacgt tagggacgat tactaacatc aatgcgttat
     3121 ttcgtgtgtt gttttcatgt tttgcaacac ctagtttagg atatgcaaat gcttattcat
     3181 ttaatgatcc tagtggaatg tgttctgtct gtcagggaat cggtaagacg attgcatttt
     3241 taataggatt gctttatttt tcggctattg ataatgctga ttttgtattt tctgatccat
     3301 ttaccgcaga agttttgtct ggaattgagg aacaggcaaa gaatcatggt tattttgtat
     3361 tggtgcataa tgttaattca gcagaagatg ttaaaactat tcagagaaat tggcgttttg
     3421 aggggttcat tgttgttggt gtacgtgtaa aagaattttt ggaattaaat aacgtttttg
     3481 atggtcctgt tgtttatatt gatacgcatc tttcaaaaga gacattaaga gaacttgaac
     3541 aacaaatgaa tcgtttattt gtaaatacaa atgattacca agctagtaca ttggcagtgg
     3601 aacatttgat tcattatggt catgagaaaa tagcgtttct ttcttttgac tacattgtag
     3661 gtgaaccaag tgttattcaa gaacgacatc aagcttatat cgatacatta aagaaatatc
     3721 atttaacctt taaatcgcat tggatatata acaactctga atttgagcga atttatcaag
     3781 aattagctga atttactgca attgttgtta ctggagatta tttagcggct aaattagtaa
     3841 aatttttaaa aaataagaat aaacgagtga tggaacaatt atcgattatt ggatttgatg
     3901 atattacttt tgcagaatta atggatcctg cgttgacaac aatacgacta aatccaggta
     3961 acaagggggc gattgctttt caccaactga ttggactggc caaacaagaa gaaataaaaa
     4021 atcaagtact actattagag ggagaattga tttctcgaga ctctgttcac aaaatcaaat
     4081 aaaaaagctc tgtgaaataa gtatagttaa caataaaata tccgaacgat agagagaatg
     4141 aactgtgatc tagcagttcc tcgtcgcaaa ttcactagaa ttagcattat ttactctaaa
     4201 ttgttcggat attttttctt gtttttaatt atgattacag tgcctatttt taacgaaatt
     4261 tgcttatttt caaaatgtat gattatatgt tagtaaacac tttcaaatat gaaaagagga
     4321 gctattatgg taggaattag ggatgttgca aaacgggcgg gtgtgtccat tgcaacagta
     4381 tcgcgcgtgc taaatgagga tccgacactt tcagtaaccg atgaaaccaa acgaaagatt
     4441 gcagaatcgg ttaattttta tcattatgtc aaaaaaagtc ccgttgcaaa aaatttaaca
     4501 aatattgcat taataacgac agtttctgaa gtagatgagt tggaagatcc ctattttcga
     4561 acgattcgca gagggattca agtcgaagca gaacaaagca aagtcaattt gaagaaaatt
     4621 attcgtttgt cagaaacacc gttggagcaa gacgatttgc taaaatgtca aggtgtgttg
     4681 attattgggc aggtgctatc ttctgtgatt gaagaagtat cagcaattaa ttcgaatgtc
     4741 gtagtgattg atgaccctag tattgaagct gaagtagatg cagtttatac tgatttaaca
     4801 aaagcaacga atcagcattt agatcgattg tataaaaaag gacaccgaaa cattgcgttt
     4861 atcggaggag gacgtgttcg tttagatagc caaggaaata aacacgtgtc agatgatgat
     4921 tatcgaaaaa tagcctatga gacgtggatg aaacaaaaag gattagaaaa atatagtcaa
     4981 atttatttag aaggctggac cacacttgac ggaatgcagg cagcagattt acttttgaaa
     5041 aaacatgcta aagataagtt gccgactgct atcatggtag gaaatgatcc tattgctgtg
     5101 ggggtttatc gttcacttca aaaaaatggt ctacatattc cagaagatat ttcgattgtg
     5161 agttttgata atattgaagt tgctgaattt ttaacacctg cattaaatac ggtgaatgtg
     5221 aatacagaag aaattggaaa actagcagtt cgcatggtta atgaacgaat aaaagaagtt
     5281 agaaatgttt cgatcaaagt gattgtttct aataatatta ttgttagaga aagtgaaaaa
     5341 aatatcgatt aaaaaagtaa acatccaaaa aagggtgttt acttttttgt ttactaatat
     5401 ttttagtaaa aaatctcgac aaaacattaa gtaaacagtt atggtgttgt taacaaaaag
     5461 aaaacgcatt caaaacagga ggaattaaga tgaaacattt caaaaaaata gctttaacag
     5521 ggatagctgt tttaactggg acattactcg cagcatgtgg tgggggagat agtaattcta
     5581 aagacgggca agtaacttta agctatgcga gttgagatac tgaccaagct ccaggactaa
     5641 gaaaaatgtt agatgaattt gaaaaacaaa atcctgatat caaagtagaa atggagacaa
     5701 cgccttggga tcaatattgg gttaaattag aagctgcaac aacgggaggt aatatgccag
     5761 atgtagtaac catgcactct agcgaatcct ataaatatat gtcacagaat gctttgatgg
     5821 gacttgatga tgttatcaaa gaaaatgata ttgacatggg aaactttact gaaggaattg
     5881 ctgatttcta tacgcttgaa gacgaactat acgcaatccc taaagatgct tctgtagtgg
     5941 ggctatggta caacaaagaa ttatttgata atgcaggtgt cgattatcca gatgaaacat
     6001 ggacatggga aacactcaga caagctgcaa ttgatttaac agatgaatca aaaggcatct
     6061 atggttttgc atcacatatt ggaacagaga ctggctactg gccatttatt tatcaaaatg
     6121 ggggagaagt atttgccgat gacaatacaa aatcaggttt gaatacccca gaagcacaag
     6181 aagctttagc tttttatcga gatattgcac ttgttgatca tgcttcacca acaattacag
     6241 aattacaaga tcctgataag ttaagtcgtt ttcaatcagg tagattagca atgatgattg
     6301 aaggaaactg gtttgcaccg ggatttttga aaaatgacta tctagttgaa aatgttgctt
     6361 ctgccgtgtt acctaaggga aaagttaatg caacaattac aaatggactt ggttgggctg
     6421 ccagtgcgag tacaaaatac ccagaagaag tgaaaaaact aatggcattt ttagctagtg
     6481 aggacgccaa taaaatccaa gcggaaacgg gggcatcaat cccagcacta aaaggctttg
     6541 aagacgagtg ggctgcttct tcagatacaa ttgatttgag tgcttttgga aaaatgttgg
     6601 agtatggagt ccctcgtcca tacaataaag atggattacg agctgaacaa gcagaagttc
     6661 aaattattaa ccgtattctg tctggtgaag taactgttga agatggaacc gctcaaattg
     6721 aaaaagaagt caatgcgata ttgagcggaa attaaattag ttaattatac aatatacagg
     6781 cgaaaggatt ctatttcgtc tgtatattaa tggatgaata ccaaaaaggg ggatattatg
     6841 aaaaatcgaa tttttggaaa atatcgtaaa gatcaagtga tatggggcta tatttttatt
     6901 tttccaacgg cattaggatt aattttatta aatatatggc cagcaattca aacagcaatt
     6961 ttaagttttc aaaaaacggt agggttcggt gatactgaat gggtcggatt aagaaattac
     7021 caaaaaatgt ttgcagacgg tgaagttttt cagtctttat taaacacatt aatttatgca
     7081 gtggtttcga tacctagtat tgttgtatta tccttgttgg tggcagtttt aatgaataga
     7141 aaagttaaag gattgtcgat ttatcggaca atttattttc taccagtcgt tgctgcacca
     7201 tccgcagtcg caatgatttg gcgctggatg ttcaataatg attatggact gattaataac
     7261 atgttggcta aaataggtct cgatggacca gcatggttaa cggatccatc gattgcgatt
     7321 tattctatta tcattgtagg agtttggagt gctattggtt ataacatggt gttattacta
     7381 gccggcttat aagaaattcc taaagattat tatgaagcag cggaaattga tggtgctagt
     7441 ccaatccagc agtttttcaa cattacgtta ccattagtta caccaacatt attttttgta
     7501 gttgtaacaa cagttatcaa tgctttccaa gtatttgatg ttatttttat gatgattact
     7561 cctaatagta ccgccatgtt taaatcacaa tcattagcct atttattcta taaacattca
     7621 tttattttaa atgacaaggg atatggttcg gcaatcgtta tgttcctttt agtgattata
     7681 ttaattatta ctgcaattca aatgaagttg cagaaaaagt gggtaaacta ttaaggaggc
     7741 tatcaaatta tgaaaaataa atttttttca aatgcgccaa tccatatcat gcttatttta
     7801 ggtggtattg caatggcatt accttttatt tggatgattt taacttcagg gaaaacgttg
     7861 gttgaatcta cccaaattcc acctacaatt ttccctgaga aatttcagct aagtaactat
     7921 caacaagtac ttgatttatt accattcatg gctttttata tcaatacatt tttaatggtt
     7981 gttggacgag tgattggctc ggttttattt tcagcaatgg ctgcatatgc ttgtgcgcgt
     8041 ctaagttttc cagggaaaaa tatccttttc agcttagtac ttattcaaat gatgattccc
     8101 ggttccattt ttattactcc acagtattta ttagcacaaa aattgggtat tttaaataca
     8161 attccagcat taatattacc aggggtagtt agtgcgtttg gtacgttttt attaagacaa
     8221 tttttcttag gtttacctga tgaattggag gaagcggcct atttagaagg tgccaatatt
     8281 tggacgatct ttttcaaaat tatgttgccg cttgctaaat caggattggt tgcacttgga
     8341 atattcacag cgttgtttgc atttaaagat ttaatgtggc cattgattgt caatacttca
     8401 attgataaga tgcctttagc tctgggatta gcaaacttac aaggacaata tgccacgaac
     8461 ttcccacaat taatggcagg ttcgttatta gcaatttggc caatagttgt gatattcatc
     8521 gttttccaaa gaaaattcat tgaaggaatt gctacaacag gtagtaaatt ataaaactat
     8581 taattagtga ttggagagta agtacatgac aaaaattaca tttattggtg caggaagtac
     8641 tatttttgca aaaaacgtat taggcgatgc gatgttaact ccaagtctac aagatgcaca
     8701 tattgcattg tacgatattg atgaaaaacg actaaaagaa tcaaatttaa tgcttaaaaa
     8761 tattaataaa aattcgaatg aaaatcgtgc tgatattgtt tcttattatg atcgcaaaga
     8821 agcgttaaga gaggctgatt ttgttatcaa tgctattcaa gtgggtggtt ataaaccttc
     8881 aacagtgatt gattttgata ttcctaaaaa atatgggttg cgacaaacta ttggtgacac
     8941 catggggatt ggtgggattt ttagaaccct acggacacta ccagtaatgt tagactttgc
     9001 taaagaaatg gaagaagttt gtccaaatgc ttggttattg aactatacaa atccgatggc
     9061 gatgttaacc atgggtgttt taaaagcgac gagtattaag actgttggtt tatgtcatag
     9121 cgttcaagta tgcgtaccag aattgtttga gcatttagga atagccgatc aatatgactt
     9181 aaatgacttt caatggaaaa ttgcaggcat taatcatatg gcattcttgt tggaaattac
     9241 aaaaaatggg gaagatttct atccaacaat tcgtcagtta gctgcagaaa aaccaaatcc
     9301 acatccagat tctgtacgtt ttgaattgtt gaaacgtttt ggttactata ttacagaatc
     9361 aagtgaacac aatgcagaat accatccata ctttattaaa tcaaaatacc cagaattgat
     9421 tgacgaatta gggattccgt tggatgaata cttacgtcgt tgtgaacaac aaattaatga
     9481 ttgggaaagc atgcgagagg acattgtaaa taatggggag ttaacacata cgagaagccg
     9541 tgaatatgct tcatatatca tggattctat tacgacagga actccgtcag tgattgcagg
     9601 aaatgtctta aataaaggct taatcacaaa cttaccgaca gatgtttgtg tggaagtacc
     9661 ttgtttagtc gataaaaatg gcgtgcaacc aacctatgtc ggtgaattgc caacacaatt
     9721 agctgcttta aatcggacga atatcaatgt tcaagaactg acagtagaag ccgctttaac
     9781 actagataaa tcaaaaattt atcaagcagc gtatttagat ccacatctat catctgaatt
     9841 gtctttaaca gatatcaaaa atttagtgga tgatttaatc gaagcacatg gggactattt
     9901 acctgaatat aattaaaaag aagctgaaag agtaaggaat tttcaattcc ttactctttt
     9961 cttagttaaa tttagtaaaa atattgacaa aacacttagt aaacagttac attagtgtta
    10021 acaaaaagaa aacgcattca aattgtataa ggaggagcat aaaatgaagt ggtctaaaaa
    10081 aattatttta gcttgtatag cactaggagc aacgatctct ttgactgctt gtggaaaaaa
    10141 tcaggaagat gcaagcggta aggtagaaat agagtttttt aatcaaaaaa aagaaatgac
    10201 tcaaacgatt caggagattg ctaaagattt tgaagcaaaa aaccctgata ttcatgtaaa
    10261 agttgtggat gtaccgaatg ctggtgaagt aattaaaaca cgtatgcttg caggcgatgt
    10321 accagatgtc attaatcttt atcctcaaag tatagaattg aaagaatggg cgaaagctgg
    10381 ttatttagag gacttaaccg aagaaccgta tttagagaat atcaaaaatg gatatgcaca
    10441 acgttttgct attgaggatc gtgtatatag cataccatta accgctaatg tctatggttt
    10501 ttactataac aaaactgctt ttgaggaaat ggggattcaa gcaccagaaa cttgggcaga
    10561 atttgaaaaa atagtagctg agattaaaga tcaaaacaaa gtaccgtttg cgattgcagg
    10621 agcagaaggc tggactttaa atggttatca ccaactagct atagcgactg ctgctggtgg
    10681 tgaagaggaa gcgaacaatg tttggcgttt ctcagaagtt aatggaatta atgctgaaag
    10741 caaagaaatg caaaaagatt ttaatcgatt agatttgtta agagaaccaa aagctttgca
    10801 aaacaactgg caaggtgccg gttataacga tacagtagtt acttttacaa aaggtgatgc
    10861 gttgattatg ccgaatggtt catgggcaat gccgatgatt cattcacaaa atccagattt
    10921 tgaagtagga acttttcctt ttccagcaga tgaagcaggt caaagtctaa cgattggcgc
    10981 aggagaccta gccttatcag tttctgcaac ttctcaacat aaagaagaag ccaaacgttt
    11041 tgtagaatat atgacaacac ctgaagcgat gcagaaatat tatgatgtag atggtgcacc
    11101 gtgtgctgtt gagggcgtta tcgagaatac tcaggattca ccattaagtg gtttaactga
    11161 acttgctttt actgatcgtc atttagtttg gttagccaaa gattggaata gtgaaaatga
    11221 tttttatacc ttaacaacaa attatttaca caatggcaat caaaaagcca tgattaacgc
    11281 attaaatgct ttctttaatc caatgaaagc tgacggaagg taggaaaata aaatgaaaat
    11341 aaaagaaatt ttaaatcgtt actgggcaat catttttgta gcaattccaa ttattttgca
    11401 gatgattttt ttctactttc caatggttca aggtgctttt tacagtttaa ctaattggac
    11461 tggtctgact tataattttg attttgtggg tttgaacaat tataagattc ttttttctga
    11521 tccgaagttt atcaaatcga ttggcttcac tttaattgtg acgctttgca tgattgctgg
    11581 acaaattggt tttggtattt tgattgcgcg ggcgttgaac gcaaatatta aagggaaaac
    11641 attctttaga gcatggttct tttttccagc ggtcttatcg ggcgtggttg tttctttagt
    11701 atttaaacaa atttttaact atggtttacc aaaaattggt agtatgttag gcattgaatt
    11761 tttacaaacc agtcttttag gaacaacatg gggagcgatt tttgcagtaa tttttgtttt
    11821 actttggcaa ggaattgcca tgccagtcat cattttctta gcgggttttc aaagtattcc
    11881 acaagaaatt attgaagctg ctagaatgga tggggcgaat gataagcaaa ttttttggaa
    11941 tattgaaatc acctacttat taccaagtat ttcaatggta tttattatgg cattaaaagg
    12001 tggcttaaca gcatttgatc aaatttttgc tttaactggt ggtggaccaa gcgatgccac
    12061 aacatctttg gggttacttg tttataatta tgcttttaaa aacaatcagt ttggttatgc
    12121 gaatgctatt gctttagtct tatttatctt aattgggatt gtttcactgg cacaattaaa
    12181 attatcgaaa aaatttgaaa tctaggaggt ttcccaatga aaacatcaaa agaaaaaaat
    12241 atttctaaat acttgctttt attattaggg ggcttcatga ttttagttcc cttagtttca
    12301 acgctattcg gttcatttaa aacaacaccc gatattatga ataatttctt tcgttttcct
    12361 aatccagcga ctttggaaaa tttccgaaga ttgttagcgg atggaattgg tcattacttt
    12421 tggaattcgg caatcatcac aatcattgca gtagttgctg tgacagcaat tattcctatg
    12481 gctgcttatt cactagcaag aaaaatgact cgtgggaaag catacggatt gatgtattta
    12541 tttttaattt taggaatttt tgttcctttc caagtaatta tgattccgat taccgttatg
    12601 atgagtaaaa ttggtttagc aaatatgtgg ggattaatct tactctatct cacttatgcc
    12661 gtaccacaga cactattttt atatgttggt tttattaaac taaatgtgcc tatcagtctg
    12721 gatgaggctg ctgaaattga tggggctagt cactttacaa cttatttcaa aattgttttc
    12781 ccaatgttaa aaccaatgca tgcgacgact attattctta atgctctatg gttttggaat
    12841 gatttcatgc taccattatt aattttaaat cgtgattcta atatgtggac actaccattg
    12901 tttcaatata attatacggg acaatatttt aacgactatg gtccaagttt tgcttcctat
    12961 acagtaggaa ttgtcacgat tacactagtt tatcttgctt tccaaagaag tattatagct
    13021 ggaatgagca atggagcagt gaaataacca ataaattatt ctcattataa aggagttcat
    13081 aaacttatga ttatatttga caatcacaca caaacatttc atttacaaaa taaaaaaatt
    13141 agctatctat taggaatcga agaaaataat tatttaacgc atctttattt tggaaaaaag
    13201 attacgcact attctggtgg gtatcgctac ccccgaacag atcgttcctt ctcacccaac
    13261 aatgcaaatg cgcaagatcg tttattatct ttagacacat taccattaga atttccagga
    13321 tatggacatg gtgattttag agaaccggcg cataatatta aattaggaaa cggtagtcgt
    13381 gtaaatgatt ttcgttatga tagctacgaa attcaaaaag gaaagcccag cttagcggga
    13441 ttgccagcct tatatacgga agatgatgat gaagctgaaa cgctgattat tcaattgaaa
    13501 gacgcgatta gtggattgac tttacagttg ttctacacaa tttatcaaaa tcacagtgta
    13561 attattcgtt ctacgcaatt agtaaataat agtgatgaaa cagtggagat taaccgctta
    13621 gctagtcaat caattgattt tccaaatcgt ccactcgagt taattcattt aaatggtacc
    13681 tgggcaagag aacgtcaaat gactagagaa aaaattcata cagggataaa agtattagat
    13741 agtaaacgcg gatcaagcag ccatcaacaa aatccgtttg ttgctttagt agatgccaaa
    13801 acagatgaat ttcaaggaga ggcatatgga tttaatttag tttatagcgg taatcacgaa
    13861 acggtgattc aaaaagatcc atttgaccaa acacgggtca ttatgggaat taattcattt
    13921 aattttggtt ggcaactaaa aactggcgac tcatttcaaa cgccagaagt cgtgatggtt
    13981 tatagtaatg aaggtctgaa tacgttatca cagacgtatc atgaattgta taatcaccgt
    14041 ttaattcgtg gaaactatcg tttaaaagaa cgtcccacgt taatcaacaa ctgggaagca
    14101 acgtattttg attttaacga agaaaaaatc atgaatattg tcgatgatgc gaagaacttg
    14161 ggcattgaaa tgtttgtttt agatgatggt tggtttggcg gtcgtgaaaa tgacttcact
    14221 tcattaggtg attgggttga aacagaaggc aaacttgctt gtggtttgga aaatttagcc
    14281 aagcaagtgc atgataacgg gatgaaattt gggatttggt ttgaaccgga aatgatttct
    14341 gaagatagtg aactatttcg agcacatcca gattgggcat tgggtattcc aggtcgtgac
    14401 cgctcaatta gtcgaaatca atatgttctt gatttttcaa gacaagatgt tcgtgataat
    14461 atctatcaac aaatgacggc gatttttgat cgtgtaccga ttgattatgt gaagtgggat
    14521 atgaatcgaa atatgacaga agtctattct gtcttgttgg actcaacgat gcaaggtgaa
    14581 gtggctcatc gttatatgtt agggttatat gaatttttag aaaagttaac aacgaattat
    14641 ccaactattt tatttgaaag ttgttcgggt ggaggcggtc gttttgatgc aggtttcttg
    14701 tattacatgc cacaaacttg gacgagcgac aataccgatg ccgtggctcg tctgaaaatt
    14761 caatatggaa ccagcttagt gtatccaatt tcaagtatgg gtgcgcatgt ttcagcagtc
    14821 ccaaatcatc aaacaggaag agaaacgagt ttaactattc gtggcaatgc tgcgatggct
    14881 ggtgtttttg gttatgagct agatctaacg caattaactt ctgaagaaaa agcagaaatt
    14941 aaagaacaag ttgcctttta taaaaagcat cgccaacttt tgcaatatgg aactttttat
    15001 cgcttggaaa gtccgtttga aggcaatgat actgcatgga tgtttgtctc aaaagaccaa
    15061 acagaagcca tggtctttta tttccgagta ttagcagaag ctgcgcatcc attagtcaca
    15121 ttgaaattag caggattagc agaagaagca acttatcaaa tggaagatgt aacatttgct
    15181 ggcgatgaat tgatgaatct cggtttttat attgactcag aactacatgg tgattatgcg
    15241 acacaacgct tttatttgaa acagatatag tagcttgaat ttacaatata agtgcaacac
    15301 caaaagagac tcattccaaa cgaagaaaat atgttttatt tacacgcatt tactaaaaag
    15361 cagcctgatt tgaattggga aaatgaagaa gtacgtgaag aaatctatgc aatgattaac
    15421 tattggttag ataaaggact aggcggattt agaatcgatg cgatattaaa catcaaaaaa
    15481 aaactagagt atggcatctt tgaatctgat ggagaagatg ggttagcctt cattgggccc
    15541 tggattctta atcagtcggg cattgaagtg tggttaaaag aaatgagaga gcggacattt
    15601 aaaccacata atagtatgac ggtagcagaa gccgatgttc ctaatgaacg tttagatgaa
    15661 tatattggtg aagatggcta ttattcgatg gtttttgatt ttagttatac ggatattgat
    15721 gtacctgaaa ctggtgaatg gtttaaagat agccaatgga catggacgga tatgcgtacc
    15781 aatattttta cgaatcaatt agttacgcaa gataaaggtt ggggcgcctt atatttagaa
    15841 aaccacgatc aaccacgttc aattaataaa tatattccag aagaatggat caatgattat
    15901 agtaaaaaaa tgttggcgac gctttttatg ttactaagag gtaccccttt tatttatcaa
    15961 ggacaagaac taggaatgac caacatagaa atggcatcat tagaagattt tgatgatgta
    16021 gctacgcatt ctcagtataa acgggcatta gaatatggat tggcaccaga gcaagcattg
    16081 aaagctgtca ataaacgaag tcgggataat tctcgcacac ctatgcaatg gaatacgcaa
    16141 aaaaatgcca gattctcaac ttctgataat gtatggttaa aagtaaatcc taattatcca
    16201 gaactcaatg cagaagctca gttaaccaat caacagtcgg tattcaatta ttatcatcaa
    16261 ttaattaaat taagaaaaaa tagtgtatac aaagacgtgc taatctacgg acaatttcta
    16321 ccagtgaaag ataaaaatga acatattttg ctttatgaac gccaattaga agataaaatc
    16381 gtattagtta tcttaaacgt tacagcaaca gaacaagaat attatgtaga tgaacagtac
    16441 caacaagtat taatcaataa ttatgaagat gttttattag atcaaagtcg aaaattgcgt
    16501 ttacgaccgt ttgaaagtat tgtattagct aattatggag gacaattatg aaaattaaaa
    16561 acgaagcaat gctcatcacc tatgcagata gtttaggaaa aaacatgggc gaattaaaac
    16621 aagtcttaga caaacattta caaggtgtta ttggtggtgt acatctgttg cctttttttc
    16681 catcgacagg tgatcgaggc tttgcgccga gtgattatac gacagttgat ccagctcttg
    16741 gaacatggga agatgtggaa gcattaggtg aagattatta tttgatgttt gattttatga
    16801 ttaatcacat ttctcgtgaa tcaaaatttt tccaagattt caaaaaaaac catgagcagt
    16861 caccatacaa agaaatgttt atccgtattc atgaattttt cccagaaaat cgaccaacac
    16921 aagaagatat tgatttaatc tacaagcgta aagacaaagc gccgtttcaa acggtagaat
    16981 ttgcggatgg tacgacagaa gaggtttgga atacctttgg ggaagaacaa attgatttag
    17041 atgtgaccaa agaagttgtg aaagaattta ttcgagaaac catcaaagat atggcgaacc
    17101 atggctgttc tttaattcga ttagatgcgt ttgcttatgc gattaaaaaa ttagatacca
    17161 atgatttctt cgtggaacca gatatttggg aacttttaga cgaagtgcgt caagaagcag
    17221 cgaaatatga cgtcgaatta ttaccagaaa tccatgagca ttattccatt caaatgaaaa
    17281 ttgccaatca tgattattat atctatgact tcgccttgcc aatggtcact ctgtattcac
    17341 tttatagtgg aaaatcagaa cgtttagcca attggttgaa aatgagtccg atgaagcagt
    17401 ttacaacatt ggatacgcat gatggaattg gtgttgtgga cgctcgtgat ttattaacag
    17461 atgaagaatt ggattacacc tctgaggaat tgtataaagt cggggcgaat gtgaagaagg
    17521 tctattcaag tgccaattac aataatttag atatttatca aattaacagc acctattata
    17581 gtgcattagg cgataatgac cgtagctatc tgttagcacg tgcgattcaa gtatttgcgc
    17641 cagggattcc acaaatttat tacgttgggt tattagcagg aaaaaatgat attgaactgt
    17701 tggaagcaac gaaagaaggg cgtaatatta atcgtcatta ctatgattta gccgaaattg
    17761 aagaagaagt gcaacggcca gtgattcaac aattatttgc acttttaaaa tttagaaatg
    17821 aatctgcggc gtttgatttg gatggaacga ttgaagtagc aacgccatca gaatcagaaa
    17881 tagtgattac acgtaaaaat aaaaacggta gtgatagtgc aacattaacg gctaacttgg
    17941 atacgaaaga atttatcatt gagtctaaag atataaaaat tttcactagt gttgcattaa
    18001 aattttaacc tattccatag aacaaaaaat cctttatact agcacttgga tgacttatcc
    18061 aagaccaata aaaaggactc atacatggat aagtataaaa caaatacagc atttaataaa
    18121 tggttttctg ccataaaatt aggaaaactt tctgtcaact cccaaaaatg tatttttgat
    18181 tacaattcgt atcgtaaaaa actgtctttt gaagctgtgc tcaagctctt tctctacgca
    18241 gttaatgaag aaaaagaaag tttgcgtgat ttgagtacag ctcttatcga ccgatcgctc
    18301 caactagaaa ccgatgtgtc atcgattagt catacccaat tgtctcgagc atttaatgca
    18361 cttgaaccta aagtgttaga agaaattttt caacaactgt tagaaaaagt tcaacatcaa
    18421 atcaaaccaa ccaagcgaaa tcatctgtat ctgattgatt ccagtacgtt ttcgcttagt
    18481 ttaaaacgtc ataagtgggc gactttccgt caaacaaaat caggtgtcaa gttacactta
    18541 aactattgtt atatggacga tactacgatg tatccaactg attttacctt aacaaatgcc
    18601 catgaacatg atctcaatca actaccagta ttggtgaatc aaccagaggc aacttacgtg
    18661 tttgatcgtg ggtattagga ctttgaaaag atggatcaga tgcattggga tggctatttc
    18721 ttcgtcactc ggattaaaaa aaacaccaaa gttcacgtga tagatactct ggaaacatcg
    18781 ccagaaacag aaattctacg agacgagctg gttcgtttag gatctaaaac ctatctaacc
    18841 gccaatttcc gactagtcac tgttcaagat aagaacggac gtgtgtttca atttatcacc
    18901 aatcgaatgg acgtctcttc aaaagaaatc tctgatatgt atcacgctcg ttggcaaatc
    18961 gaattgtttt tcaagcacat caaacaacac atgaccatta aaaccttctt ttctcaaagt
    19021 gaaaaaggcg tgcagaatca attgatttta acgatgattt ccgctctcct cacgtttctc
    19081 atcaaattgg agacgaaaac ggaaaaatca gtgttccaaa tcaaacgatt ctttcgttat
    19141 ttactgtttc agccctttga atgttgtcta gaaaaattaa ttcccacatg agaaaaaaga
    19201 aatttggctc gttacttttg gttttcagtt gaataacaga taaaaaattt tctggaaaaa
    19261 gtcatcctct gcgtcagcac agtttttttt gacttatttt cagaggaaat agttttcaga
    19321 atattctaaa atgttttatg caacactagt gatatttttt agaattagat ttctaatgtg
    19381 cattttttga gtattaagga gcaagtatac aaagatttat aaagctgatt aaatttgaat
    19441 aaaaatatgc aggaacgcta ctatttttag tagtgttctt ttttatattt gaataaaaaa
    19501 tgtggtggtt aaatggtggt tataacaaaa aatgaattaa tgaaattagg ttatgggaag
    19561 tatcagtctg agagaatcat acgacaggca aaagcaatta tggtttcaaa aagctatacc
    19621 tattacgaaa atagaagatt aggactagta cctgttgaat ctgtagaaga agttttaggt
    19681 atgaagatag aggtagagga ggattttcag aatcatggtt aattttaaaa aagataaaaa
    19741 tgggaaatat cattttactg ctagtttggg attcgacaaa cgaacaggga aaagagtaca
    19801 aaaaaacgta gaggggttaa aacagttaaa gaagaaaaaa agcgtatacc gaacttgttt
    19861 ctaattatgg aaaagaagca gaaacttctc aaagtactat gttgtttgag gagttttttt
    19921 ataaattatt cctaccttat tatcaaggga aagtagaaga aagaacatat aaaaatcggt
    19981 tatctacaat caaaaaaact tttcttattt ctttaaaatg gagttaagag aaatacgtcc
    20041 aattgacatt caaaagtggc aaaataattt attgagcaaa tataaaaatt cttatgtaag
    20101 aaacatgtat gggatttttc agatgtcatt agatcgagca gttgttttgg gactacttga
    20161 aaaaaatcct gcaaaagtta ttggaaatgt gaagaaaagg aaaactacag ttgatttttg
    20221 gacaaaagaa gaatttacaa aagttatttc aactttttat attgatgatt tgtaccaaca
    20281 ttttggtttt atttgtatgt ggttactttt tatgaccgtt atgcgtttgg gagaagccac
    20341 tgcattaact tggaaagata ttgattttga aaataaaaac ttgcgtgtga ataaaacact
    20401 ctattataag agagccaaaa cctatgagtt tgtagaaccc gaaacggctt ctagtattcg
    20461 tacaatcgaa ctagacgaca atacaattac ctttttaaaa gcttggaagg agcgtcaagt
    20521 ttcaatagga ggcatgtcgt ttgtactttc ttataatgga acacctactc agaaatatac
    20581 aatccgtcat attatgagaa gacatgcaac gatcgttggt gttcatataa tccgcataca
    20641 cggattaagg catagtcatg cttctttgct tatatcacaa taaaaagatg cacttcgaat
    20701 taaagaaagg ttaaaacatg ctgatgtaca aacgacttta ggaacttatg gtcatttgta
    20761 tctaaattca ttgagagaga taacaaatga tcccacagat tatatccaaa ctaatttttc
    20821 taaaatcaaa ccgacaccta tttacgataa taaaaaataa atgataaaca aaagtaggat
    20881 cacaccaaaa gaaacacact agaaaaacta taatacaggc ttttctagcg tgttgtttct
    20941 tatttccgcc tatttataca ttatactcat aaagcattta atgcatcgat cgtagccgca
    21001 ttgtctatat gggtatataa agttgttgta ttggtacttg aatgtcccaa ttgttgggca
    21061 gttaatacca atgaatttgt ctgttggtag agtctagtag ctaatgtatg acgcagtttg
    21121 tgagggctga cttgaattct aaagcctttt gaatattttg ctaccatccg ttcgattgca
    21181 ataccggata tacgcttggc ttctccttgg taaattgcta gaaataaagc tttttcgttt
    21241 tctgttactt tatatcgttc tttccgaata gctagataat tagctaaata ttccattgcg
    21301 aatgctgcta tattgacagc atctctttta tttccttttc tagttactac cacattattc
    21361 ttatctaaag ataggtcatc taaattaata tttataacct cggagagtct caatccagat
    21421 cctaaaatca gtgcattgat cgccaggtct ctttctacat ctcgttgata atagatcaaa
    21481 gctcgtttac tcaaagtatt tttatattca ttggcaatat aatctagata attttgtgta
    21541 tccttatcta gaaataattt tttctcaatg gcattggcac gtgcagctaa cgtagtttta
    21601 tctgtgatgg ttgctacttg atccatagga ttattgtcta agtatggttt tcctagagga
    21661 ttattggaac ttttcgaaag atatttaaat agaaccttta atgccgtgat atttctattg
    21721 atagtagaag tagatagacc taagttatta ttatctttga gcttagtttt tgttgtctct
    21781 ttttttacat tttcttttgt gcgacgtttc aaatgagatt tgtacaagtt taggtcatag
    21841 gcagttaact gtcttatcga ggtgatagaa gtatcaggaa cgatagactc actcagaagc
    21901 cattcataaa agagcttata attttttaga tattctaaag tggttcgagg tgattgatct
    21961 ttatcctcac gatcttgaac aaaatctttt atataatcgg gcatatgaag tatgattgta
    22021 tctatttttt gatatatttc tgtatttttc atgtcattca tcctttcaat aagtagggga
    22081 gaagagtatc tctataattg gactatacca attatagaat gttttgtcaa ttggtatgct
    22141 ctaaaattta ttaatttgtt tcaaaaaaag catataaaca ggtatacgtt taata
//
LOCUS       DAXLPC010000041        22028 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.041, whole genome shotgun sequence.
ACCESSION   DAXLPC010000041 DAXLPC010000000
VERSION     DAXLPC010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22028
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.041"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(61..1371)
                     /locus_tag="ACF3UE_001520"
     CDS             complement(61..1371)
                     /locus_tag="ACF3UE_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFD3634930.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1383..2801)
                     /locus_tag="ACF3UE_001521"
     CDS             complement(1383..2801)
                     /locus_tag="ACF3UE_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3634931.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3041..4609)
                     /locus_tag="ACF3UE_001522"
     CDS             complement(3041..4609)
                     /locus_tag="ACF3UE_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFD3634932.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4613..4894)
                     /locus_tag="ACF3UE_001523"
     CDS             complement(4613..4894)
                     /locus_tag="ACF3UE_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFD3634933.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(4891..5814)
                     /locus_tag="ACF3UE_001524"
     CDS             complement(4891..5814)
                     /locus_tag="ACF3UE_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFD3634934.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(5811..6689)
                     /locus_tag="ACF3UE_001525"
     CDS             complement(5811..6689)
                     /locus_tag="ACF3UE_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFD3634935.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6676..8013)
                     /locus_tag="ACF3UE_001526"
     CDS             complement(6676..8013)
                     /locus_tag="ACF3UE_001526"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFD3634936.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8016..9119)
                     /locus_tag="ACF3UE_001527"
     CDS             complement(8016..9119)
                     /locus_tag="ACF3UE_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFD3634937.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9193..10701)
                     /locus_tag="ACF3UE_001528"
     CDS             complement(9193..10701)
                     /locus_tag="ACF3UE_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3634938.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10667..11359)
                     /locus_tag="ACF3UE_001529"
     CDS             complement(10667..11359)
                     /locus_tag="ACF3UE_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFD3634939.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11381..12355)
                     /locus_tag="ACF3UE_001530"
     CDS             complement(11381..12355)
                     /locus_tag="ACF3UE_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3634940.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12655..13527
                     /locus_tag="ACF3UE_001531"
     CDS             12655..13527
                     /locus_tag="ACF3UE_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3634941.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14109..16307)
                     /locus_tag="ACF3UE_001532"
     CDS             complement(14109..16307)
                     /locus_tag="ACF3UE_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3634942.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16539..17531
                     /locus_tag="ACF3UE_001533"
     CDS             16539..17531
                     /locus_tag="ACF3UE_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3634943.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17591..19012
                     /locus_tag="ACF3UE_001534"
                     /pseudo
     CDS             17591..19012
                     /locus_tag="ACF3UE_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
     gene            19005..20504
                     /locus_tag="ACF3UE_001535"
     CDS             19005..20504
                     /locus_tag="ACF3UE_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFD3634944.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20543..21937
                     /gene="uxaC"
                     /locus_tag="ACF3UE_001536"
     CDS             20543..21937
                     /gene="uxaC"
                     /locus_tag="ACF3UE_001536"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFD3634945.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6670 a         4493 c         3823 g         7042 t
ORIGIN      
        1 atcattaaaa aaaataaagg tcaagctaaa atattattta agcttgacct tattataatt
       61 tcaacgattg tcaaaagtat tgtttgcagc tgtgttgcca gtttctatag ataaatcaca
      121 gcttttgaaa cataagtttt gtactgcttc gattcgcccg aattcttttg cagttatttg
      181 gcaatgagaa aagcagacat cttctatagg cttttcagga aatgctacta aatcaaaagc
      241 tcgggaagga agtgagtaac ctggagaaag gcatgcctgt acgtttttga tgtgtatgtc
      301 tttgactttc gtcatttgct ttgattcagg tatttcttca gccactgctt gccaactttc
      361 tggcatttga gcaaggtcat tgctattttt tctattgtat tcattatgcc agtccattat
      421 ccaagaaaaa ggaaattgta catcaatcat attcagattt tctaccctga tattttcgat
      481 cactccccct ctttcttttg aagatttcat tcgaatacca cagtctgact gaaaaaaatt
      541 gatatcgtga atatatacgt cactaactcc agcactaact tcgctaccaa tagttacacc
      601 gtatcctgaa cggattttac atctagcaac ctcgattctt gatgattttc gattgactct
      661 tgcaccattg ccatctctgc cagacttaat agcaatacaa tcatcaccac aggccaaatc
      721 acattcatag acacgcacat ttgttgaaga atcaatatca atcccatctg tacttggtcc
      781 atcattgttg cggatgatta ctttttctac taatacatcg ttagaataag tgatttgcaa
      841 gttccaaaaa cctgatttct gaaaaatcaa atcacgaaca acaacatgtt ctgcatgata
      901 cagtaaacaa gcgcgtggac gtttaatagc ataatccgca atccaacgaa gtcccttttg
      961 atcgtattca gctcttgtcc cgcttttttg atcttttccc caatacagct cccaccaatg
     1021 gtctccttga ccgtcgatta ttccttttcc ttctataaga atatctttcg ccgagagaac
     1081 attcaaaatc gctgctggcc atttcatttc tacgccggct actcgtgtat cgatttctgg
     1141 aaatgcttcg atatctgttc tccccttgag gactgcacct tcttcaaaga taagatgact
     1201 cttatctttt aaaaaaaggg ctccgactaa ataaatgcct tttggaataa atacaggtaa
     1261 gtgttctttc gcaccttgat cgattgcttt ttgcagtatt attgtatcat cttgttgagt
     1321 gtcgtttgtt ttaaagttca aagcattgat aatccctttt tttgtccgca atacgtttct
     1381 ccctatcttt cattgatttt tttcaattct tcaccaataa atacagtttt tgaacgattc
     1441 agtgggtaac ctactagcaa aatgattgcg gatacaaata agcagaatgc tggtaacaag
     1501 tttgccatcg tataaatcct ttcttgtact aaaactgatt ggatggctcc acctgttgta
     1561 gacgattggt aaccaatgag tgccagcata aatccgccta ccgctcctgc acatgcttgt
     1621 cctacttttc tcgcaaaaga atttactcca tatactgttc catcttctct taagcctgtc
     1681 ttatattgat gataatcaat cacgtcagta atgaatgccc agaccatcaa attgaataaa
     1741 ccagatccta aagtagcgat aaataaaaga atcagatata cccatgcatt tgttatatga
     1801 aggaaataca tcagcaagta catacatgaa gaagcaagta acgcaaatac gcttgcttcc
     1861 tttttaccaa ataattttgt cagctttgta gcaaatggtg ctaaaactac tactgttccg
     1921 taagtaaata aaagagcaac agacattgct tgtttattat ggaagtaatc attgaataaa
     1981 taagtcatat tcgtcccagc taaaatctga ttgatcacaa tgaaaatgtc aacaatgact
     2041 aaaataatca gtgctcgatt agctaacaaa ccttttacca actgagaagc agatactttt
     2101 tcgtttttga caactcttac tctttcagta gtcaatttac aagttaacat atatgcgaca
     2161 aatgctattg cagcacatcc gattgaaatc caaaagaaat gattccctga aacgacttgt
     2221 tgtccactct tgttatgggt atacattaaa atcggaatga agaatcctgt agttgatccg
     2281 ccaatcgcag aaccaatgct tcggaacgtg gacaacgagg tgcggtcatt aggatttgag
     2341 ctaattgctg ctgccattgc tccatacggg atattgattg ttgagagaaa aatcccataa
     2401 acaatgtatg aaacaaaaat ataagcaatc ttcaccgtca ttggaagatg ttggacgaat
     2461 ggcaaaaaca aaatgacagt cactaagcaa aatggatact tcatttttct gatccaagga
     2521 ataaatcggc cagtttctgt taactctgag acatcacata atcttccaac catcacatca
     2581 gcaaacgcat ccaaaattct cgaaatcaag aataacgtac ctacgattgc ccctgaaacg
     2641 ccaagaacat tcgtataata aatcatcaag aaactattga ctaaacctaa aataaaacag
     2701 ttacctagat caccgaacat gtagcctatc ttatcggaaa tcccaaattc ctttttttct
     2761 ttttttactg tatttgctgt aacagcattt tgtgaaagca tttgaattcc tcctacctct
     2821 tctagtaaac gttttcaaaa ttataactct ttttttcttg tttttatatt cacaatgttg
     2881 gctttttatt gcattatctt gacagataaa aaacaaaaaa taatctaaaa acattgatgc
     2941 ataagattga taactttttt tacataacaa tatatacaaa caaaaaaatt cactaactag
     3001 tgaaaataag ttagtgaacc tcatttatta aagaattaaa ttacagatga tcttttccat
     3061 catacttgaa aaactcaaaa tcagcataac ttcctctttt tttatttaga tcatgcactg
     3121 ctatcccgat aaaatttcca gtaaaccctc ctgagagtat acacatgttt ttttgcggac
     3181 ctactttctt ccattcttca gttgatacgt ctttcaaatg aaactgtgct gtctctttct
     3241 ttacagtgac tttcaaaaaa gtcttctttt ctgtgagtgg aatcgtccaa tcttctattt
     3301 gtgctactcc gttttctgat tctatcatac gtaggcattt tcccttgtcc tcattccaag
     3361 taacataaca ataaatataa ttggattcat ttaagtacag taccagtcca gccatctgat
     3421 taaaattatt aggcatgtat tcaaatgctg tctccgcatc aaaagtaaaa tccgtttgcc
     3481 gaatagctaa caaatgatgt tcgaaggtag attgaagaga ttcaccggaa atcagacgta
     3541 aaaaacctgg tctacatttt gtatcacacc aatcagcatt tggcaaaatg cgtctggcat
     3601 tccagttctt ctttagctct ccttcaaatg tatccataaa ctgatgatct ttttcttgtt
     3661 gtacctcttc atttgtctca atcattattt cttccatcgg agttgtctgg ctatctttaa
     3721 gtcttaacca atcgtcggac gtccaataca cttcttgaat agcggtttct cttcccaaaa
     3781 tagccgcacc gtttaatggt ctggtacaaa gatatgtcat gtaccatctt cctgacgggg
     3841 tttgtactaa gctcccatgt cctgtacatt gcaatgtaga agcaggtttg tcactagctg
     3901 tcagcatagg aaaaccagga tcaagctcgt aaggaccagt aatattcttt gctcggcaaa
     3961 ctgtaactga atgtcctctt cctgtaccgc cttctgccgt catcaaataa taatacccgt
     4021 tacgaaaata caaatgtggt gcctccgttt tcgctaattc tgtacctgca aatattttat
     4081 agatgggacc atcaagcttc ttcttctctg catcatattc ttgtaatacg ataccgctgg
     4141 atttattcgg tgtgtccaga cgataatccc atagttcatt gacaagccat ttttttcccg
     4201 tttcaagatc atggaacaaa gaaggatcaa agccgttact atttaaataa attggttcgg
     4261 accaaggacc tgtgatctca gatgcagtga tcaaataatt gtggacatct ttaaacggac
     4321 ggcctgcact tttgacatct gtgtaaacaa gataaaacaa tccatcagca taactgatct
     4381 gtggcgccca tatacttcca tttgtaggat ttccttgcaa agatacttga gtggtcaaaa
     4441 tatccgttgt atgtgaccag ttgactaaat ttttcgactc atatactcgg attcctggaa
     4501 gccattcaaa agaggagaca ataatgtaat accgctcttt cactcttaat atattaggat
     4561 ctggattgaa tcctcttaaa ataggatttt tcactttgat agtctgcatg attcaggctc
     4621 cttttctcat tcttactcga tataaactga atgccccagc tgctaaaaaa gcaagtgaaa
     4681 taaacaacac aacggcaaac agaccagtca tgtcctgtaa taatccaaat gtattttcta
     4741 aagacaaagt tgaatgatct acagcaagcg actgataact ttttttaaac tctgacgcag
     4801 acatattact taaagtaact gctaacccgc caaagaaaat caaagataga ctgccaccga
     4861 ccattcctag caatagttcc cattttcttt tcatttctga accccctgct tttctaaatg
     4921 tatccattca ggtcttttga tcgatgtttc ataattgtta ttacgttcag agaatttgac
     4981 agtctgttca tttttcttgt catcccaatt atcccaacca gttgggtgaa catgcccacc
     5041 tatcttacac gcttcaaata agacatttgc atacggacgc cacggtcttc ctaaatagac
     5101 gtttctagta tcaggttctg cagtcaaggt acagctttca aaacgatacc ctgttttttg
     5161 atttttcggc gtagatgctg ctgtgatgta tccaggattt ttactggcta agctatggat
     5221 atgacactga tgaaaaacgg catctgcccc accaaatatg aaatccaccg ttccttcaat
     5281 ccagcaatat tcataggtct gacgacaata ctcaggattg gcagaagccg gtgtacaaaa
     5341 aggagtacca tctttttgca aatcaggcaa cggacccgtg cataaggtat cctgataacc
     5401 agatagtcga cagtttttta aagatacgcg atctcctgaa ttgaataaag caacagcctg
     5461 tcctaccttt tctcctggac ctgctgtatt ttcgatgtga agattttcta atacgacatt
     5521 cgatccttct aagaaaaaag tagcacttcg gaaagtccct aactggctac cgtcaagata
     5581 ctcctgtttt gcaaaacgat taccggagat aactactgtt cctgctccca caagtttaaa
     5641 attggataat ctgctttcta tatattcatc atatcttcct tcttttacta tcaagacctt
     5701 tggatggcta tccggcaggc ctgccaaata atcgattcct tcttggatag tttcaaaatc
     5761 cgtcggggta tctatagcat tctttccaat tatcagtttg tctttcatcc tcataaatgc
     5821 tcccttatga attgtttcca aatatttctc atttcttgtg tttccatatg accgcctgtt
     5881 aaagaaaaag aagaaaagtt ttctggacta cccattgatt gatacttttt gtccagccct
     5941 tttctcagct tcagtacgcc ttcgtccaag cacatcgtat cgttttttcc aactaagcta
     6001 agacgagggc gcggagcgat tttttcttgg attgctaacg ttgtataagc tgtcaataga
     6061 tttggcacat agtaataaaa cccatgatga tctaggcggc gatgtagcaa aagtgtttcg
     6121 atgtccacct gtgccgctag atcaatacaa actttgacac gagaatccaa tgctgtcacc
     6181 caccagctta ataagcctcc catagaaaga ccaatcgttg cgagccgttg agtatctgtg
     6241 tcttcccttg tctccaaata atcgatcaag ctgatcacat cataaatacg cattccccat
     6301 aacgtttttc ctgttaataa aaattgtttg aacaactcgc tttcagaaat acctccgcgt
     6361 tcttcaaatc cccaagcatc aatcgaccaa acagcatatc ccattcctgt cagtacttct
     6421 gcaaaagatg gagaagctaa gtaaggagca ccatggatca attcactttt cccgactgaa
     6481 aaatctccgc cgtgagaatg caggtaaagg accgtcggaa acggtccttc tttttctgga
     6541 taagcataga gggctggtac tgtttccaat tcatttaagt acaattgata gtattcaagc
     6601 ataaaaccgt tttgtttttc tcggtataat cgttttccac taggggtatg tctgctagat
     6661 ggagcaccta aaaaatcatt caactgcata agcaaagttt ttacgaacaa ccagttcatc
     6721 catattttct gattgatttg attggaattt ctcaatactg atttctttag tattttctaa
     6781 tagaaatgct ggtccctcgt gattttcaat cgacatctgg ttaaaggaaa ccttacccgc
     6841 aaagccaata taaaatcctt gtctgctcat ttcctctatt cctgtcatca tagcaggaac
     6901 accgggaact gcatcttggg ccatcgagac atcgatattg tcaaatgtga tttcttgtat
     6961 gaattgttcc gctaatccat aaataaaacc tgcagaagca tggacattcc ttgccgtgat
     7021 attcgaaaaa tggatccttc tgaatgctga tgtccgttca tctatcggat aagccttttt
     7081 ttcccataca tacggttctt tccctcgcgg accacagaaa taataaagat tcagtataaa
     7141 tggacacatc acattatcca tgactatatt ggatactcga atatcttcaa cgatcccgcc
     7201 tcgacctcgt ctagatttca atcgtattcc tcgatcagtt tcttggaaga tacaatttga
     7261 aatggtaata ttacgaatac taccactcat ttcacttcct aatacgacac cgccatgtcc
     7321 atggaccatc gtgcaatttg tgatcgtgat attttcgcaa gcgatccttt cgtacgtatc
     7381 ttcagtccct gccttgattg caatacagtc atctcccacg tcaatatggc aattactaat
     7441 acgcacattt ttgcatgatt ctggatcaat tccgtctgta tttggtgaat ccgctgggtt
     7501 caagatcgtc aagttatcaa acgttgcatt actgcaaaga atcgggttga tcgtccaact
     7561 tggtgactgg atcaatttaa tatctttcac agtaattcga tgacagttat ggaaactcat
     7621 caatttagga cgaggataag cgagattatc tggttcattt ctaaaagtat gccaccattt
     7681 ttttccattt ccatctaatg taccgaaacc agtgacagag atgttctcta cattttgagc
     7741 atagatacag gaagcataaa cttttcgatg gactccttcc caacgtgaat gaacaacagg
     7801 ataatctttt ggatcgtcag agaatttcag aaccgctcct gcgcttaaat gaagttcgac
     7861 attgcttttt aaaaataaag ctcctgttag aaattcacct gctggaacaa ctacggtccc
     7921 gcctccgtca cttgctgcag catcaatggc ttgttgtatt gcttcagtat tcaattcatc
     7981 aattgatgcg ccaaatgtca aaatatcata catatttata atgcctccac ttcaatcaat
     8041 gcttgcaaga atgcaccaac gcctttttga tcattacaaa taattggttc actgatgtag
     8101 taagcatatg aaccatctcg ctgatctgct ccgcctaacc ctgctacttg acagttttta
     8161 ttcaagttca gccagccttc ttttgtttcc agaacaaatt catcaagtaa tccttgatgt
     8221 gatttcttca cttgtggaag ccattcttct ttgttcagca gtcccaaacg tattccttta
     8281 gccattgcgt aaacaaacat actactgccg gaagcttcca gataatttcc tttccgtttt
     8341 gtttctgttg ttacttgata ccatgtcccg ctgttttctt cttgatatgg aagtaatgca
     8401 gccagtgtct tttctagaat ttctttcagc aaagaacaat ctgtttcttc atgaagtaat
     8461 tcataggtat ctgctgcagc catcaaatac cagccaatcg atcggctcca aaaatgatgg
     8521 gatagacctg tttttggatc agcccatggt tggaccttct tttcatccca tgcatgaatc
     8581 agcaaatttg tttttggatc gaatagatgt ttataactga tttcaaactg tctcaaaaca
     8641 tcttggtaat ctttttcttc actaaaattc tggataaatt cagcataaaa aggagaaccc
     8701 atatataagc catccaacca aatttgataa ggataaattt ctttatgcca aaaagctcct
     8761 tcggatgtgc gtggatggtt tgccaactgc tgggaaagga gttctgctgc ttttttatat
     8821 ttttcttcgc ctgtttcttt gtacaataaa aagaaaagct ttcctgtatt tacatggtcg
     8881 atattgtatt cttcaacgct gtagccacgg atcgttccat cttcttgcac gaaatagtcg
     8941 atattgtctt ttatgaaatc aaaataaatt ttttcttggg ttcgttccca aagtaattgg
     9001 aaccctttaa gtacgacgcc atagtcataa gaccattttc ctttatacca cttttcttca
     9061 tataagcgag gtgttctttc catgatactt tttgctaatt tctttgacca gttttccatt
     9121 atttgctctc ctttaaaaat taaaatagga tttgggacaa ataccaagaa gtatttgtcc
     9181 caatcgtcta tattactgtg ccgctgcttt gtatgcttcc tcgtactctt gtgtgattcg
     9241 atcgcctcct tgtgctttcc agtcttctac agcttttttg aatccatctt cgtcaagctg
     9301 tcccatgatg tattgcaccg tagcatcaat gacgattttt tcaatttctg atcctacttc
     9361 attgttcgtc ggtgaatcca atggcacaga aggatccatt acagcaaatt cttcattttc
     9421 tttgatcaat tgattagaga attctttttc agggtctgta tctttgaaag agaacgtcac
     9481 ttcactagga cgagagcttg ataacggttg cacctcttgt tgccaaagat ccatatcgat
     9541 aaattcgata gaaccatcat cattcaattc ataatgcgtt ccttcgatac cgccagtcat
     9601 caatttatac acatcttctt ctaaaagatc atcaacaaat tgaagtaatt tcttcaattg
     9661 tgcttcgtct tttacttgag atttgggaaa tgctagcaag ccgccaatac catttccttc
     9721 tgaccaaaca tgataaccgc cgccttcacc atctgagatc ttgtttacag gcactaattc
     9781 catatcatct tgaatacctt gacccatcgt cttcagattc ttgatatcca ccattccagt
     9841 gtagattcca gttcttcctt gtgcaaattg ttcttgctga tcagtctttt gggtaactgc
     9901 aaagtcttgt gccaaatagc cattctcaaa tagatctctt gaaaaattca aagctttcat
     9961 atactcttct gtatcaaatt ctggagtgaa tttgccatta tcgtctacag cccagccatt
    10021 tggtgctcca aaataagaag tgaaaagttt aaagctggta taacgaatat cactaggcgc
    10081 acgatcgcca aaaccaactg tgtcgtccac accatttcca tcaggatcgt tttctgtaaa
    10141 ttgtttagct acttcataaa gctcatccat ggtagttgga acatctagtc ctagattatc
    10201 caaccagtct tttcgaatga ctaagccagc acgagcgtag tctttttgta tcggtacgcc
    10261 gtacaaggca ccgtcgatac tcgcagcttc gattctatct tcagaaattt gacttaaatt
    10321 tttatagtct tttaaatatt ctgatacatc ccagaatacg cctgatttta acgcattgcg
    10381 gacagaagag tttttcaaca tcgcaatttg aagtgtaacg atatctccta gttcatcaga
    10441 agccaatgca gttgttaatc tttcttcttt tgaagcatca ggaatccagt tgaatgtcag
    10501 ttccgtatcg gttttttctt cgatcaagtt cacaatcgtg tctgtaggcg gtgaagcatg
    10561 atgcaaaata tttaaccaag tgattttagc ttttccatct tctgtctctg aagaactgtt
    10621 acttgaactg ctgccgcatg cggcaagtgc tagaattcct gcaaaactaa gacctaattt
    10681 tacgagcgtt gcttttttca taaattttct ccttcactgt tttaataata tttttgtttt
    10741 cttctgtttt ttctgtatat gagttcttcc attccaaatg gcaaaatata gaatttgctg
    10801 tccacgtgac tgcggaaaag aagagactgc caccgataaa ggttaaaaca cctggcattg
    10861 tttggatgat catcagataa atccctacca tacttaatat caacactaat gagtaatgaa
    10921 gatgtgagaa tccgaataaa aatgccattt tcattttgaa aaaatatcct ttccaatcat
    10981 aatgagccat gattgggaaa atatagagtg ctgagagcac atatatgaac gcagcaatat
    11041 acaaagcgat cctaagatac caattgtgta tgaaagaaag atccacaagt aaaacaatcc
    11101 cgatggcgcc atatatccag ctcatcagca aggtttcacg atagttttct ttaaaatatg
    11161 tgaagtacgt tttcgtcaaa ggaaacgttt cttttgagcg cagccatttt ctaatcactg
    11221 caaccatcgc atacgatgca ggaccgaaag taaaaactcc caaacctgcg atgactaaac
    11281 cgccccacag aaaattcaaa taaaccaact gtaaaatacg atttagcctt ccgtttattt
    11341 tatctaatga ctgcagcata tctttccctc tctttctatc ttagtaaacg ccgtcttctc
    11401 ctagcttttt ggcaatctta ttagctaaaa ttaccataaa caatcctacg acccctttaa
    11461 acaatcccat tgctgtactg aaacttaact gtccattctt caatccagct gtataaatat
    11521 aggtgtcgaa aatttctgca acgcttcgat tcaatgaatt caataacaag tacatatgct
    11581 cgaaccctaa gtctaatgtc tgaccgattt ttagaatcag caaggtaatg attactggac
    11641 gaattgccgg caatgtaaca tgccatgttt tgcgtaagcg tcctgctcca tccatttctg
    11701 cagcttcata caactgtgta tcgactgcag ttatcgctga aaggtagatg atcgtagacc
    11761 agcccaactc tttccagatc acttgtccga tatatactgt gcgtgtccat tcaggggatg
    11821 ttagaaaact gattttttca aatcccattg ttgcaaggaa ttcattcaat acccctccgt
    11881 caacattcaa aaatacataa gtaatcgaaa caatgattac ccaagacatg aagtgaggga
    11941 tgtaaatgat cgtttgaatc ccgtttttca atcgtttgtt cgttacttca tttaatagta
    12001 aagacaaaat gattggcatc ggaaaaaaca cgaagatatt taatccgaac aagatcaacg
    12061 tatttcttaa taatgtaaag aatgtcggtt ctgtaaacaa acgaatgaaa tgtttgaaac
    12121 cgacccaagg acttcccatt attcctaaaa atggttgata atcttgaaaa gcaataacga
    12181 gtccccccat aggaagatac ctaaaaatca agaaataaag gactcccggc agaatcatca
    12241 catataaaaa tttattcgtt ttgattcctg caattatttt ttttcgtctt ctgagctttt
    12301 cttctttttt cgatagcgtc agttgaaatg gttcttgttt ctttacactt tccataagcc
    12361 cctccttagt tttgtgaatg tttgctgctt atgacttcat gatagataac tatctgaatt
    12421 acgtatataa tcatttttat cgtaagtaaa aacgcttaca tagcaatgat ttttgtgcta
    12481 tacaaaacga taaagtgtat tttttcacaa ataaactacg catagcaaac cttctatttt
    12541 tttctatctg acacttagca taggaaatga ttatatacgt aatctttcac cgatgataaa
    12601 ttgaacatat agaaacagaa acatttaatt tattttgagg aggagcctat ctatatgaaa
    12661 aagaaagtct ctataggaga aagaagtttt acacttttca acaatacgtt tctaattttg
    12721 ctagctttga tctgtatcgt tcctttttta aatatcatcg ctacatcttt tgcttctaca
    12781 caagaagtcg tcgcgaaaaa gtttatcctt tttcctacta ccttttcttt agacgcgtat
    12841 cgctacattc tttctacgcc gaccattttt agagcacttg ctgtttcgat tggtgttaca
    12901 ggtgtcggaa cgatcgtcag tatgtgtgca acttcactga tggcctacgg tctttccaga
    12961 aagtatttgt ttggtcgagg tttcgtcaac tttcttgttg tattttctat gttgttcagc
    13021 ggggggatga ttccaacgtt cttagttgtt cgttctctag ggctggtcaa ttcttactgg
    13081 gccatgatcc tgcctgtggc tgttaatgca atgaatatga tcattatgag aaactttttc
    13141 caagccttgc cggatagttt ggaagaatca gcaaaaatgg atggttgcac agattttggt
    13201 gtatttttca aaattatgct gccattagct ttaccgtcta ttgctactat ctcgcttttt
    13261 tatgctgtta cttactggaa cacttatatg actgctattt tgtatatcaa cgattcatct
    13321 aaatggccga tacagattct tttacgccaa atcgtcattg tatcaagtgg gatgcaagca
    13381 gaaagtagtg ccgttgatgt gattccacca gcacaaacag ttaaaatggc tgttatcgtt
    13441 attgcaacag tgcctatgct gattgtttat ccttttgttc agaaatattt tgtcaaagga
    13501 gcactcgtag gttctgtcaa agggtgatta tgtactgaac gcaaaatggt agttgtgtca
    13561 gaagtggtca gcttcaagaa ataagaaggc atttacgaaa attgcttctt aaatttttgt
    13621 gaaatttcgg cttatttttc gaagaatcta ctcctggaac accgtgtatc agaggttgtg
    13681 aaagagacgt tcagccttga gcgatgataa aaactctcac aaacattgcg acgagtaacc
    13741 cacaggagca ataagaagcg attttgaaaa atagcttccc atatttcaca aaattatgcc
    13801 ttattgtcga tagcctgtct cttgaacgcc atttattcgt aaaaaagaac tgtgacaaga
    13861 cttttgtcac agttcttttt gcgtgcttag ccttgaaatt taactatcca taaatacaaa
    13921 tactagggtt attctaactt cttttattgc ttgaatcagt ccacaagaaa aacagcctct
    13981 tgattaaacg gcgtttatct tgttgattct gcggcaataa aatcagccag cagcaaaaca
    14041 tgaagtgctg ttttttgctg tcctctttta ttgcttgaat cagatcacaa gaaaaacagc
    14101 ctcttgattc acaaatattt ttttcgatat tctcccggcg taatcgattc cttcttttta
    14161 aagaaacgaa taaaattttg cggatttcga tattgcaatc tttctgcaat ctcttttacg
    14221 gagaggttag tctctttcaa ccattttttt gctacctcta aacgatgatt ttgaacaaaa
    14281 tcaccaaatt tttctcctgt ttccttttta aatacattac ttaaatagtt agggttataa
    14341 tgcaacctat cagcgatcac atctaaagac agatcacgat catattctgt gtagacgata
    14401 tgcataatat tctccgacaa atttttaaat tcatgatcag tgattgcttg agagcattct
    14461 gtgattggca gaactaattg ttctaaaaca agtttttcta gttctttggg atgataattg
    14521 ttcagtgctt ttacataaat ttgtttcatg ttatcaaagt tttttgaatc tactcccaat
    14581 aactgtccta attgaacgag ttcattgatc aagcggaccg aaactacttc ccgactcaaa
    14641 ggatttttat tttgtgcaaa caatgcatca atcaattcat gtactaaatt cttcacttcc
    14701 tgatttccag aacgaatggc ttcaaacaat cgattttgtt cttctatcgg atatctaata
    14761 agtgtttttt catgagcagc aggaacgatt tcctgataaa aaataattga acttggacca
    14821 gtatttacac gataatacag ggcttctttt gcccgatcaa ccgattgctt gctttcattc
    14881 agcgtttcga accggttact gatgcctata ctgatagtta aattcaagta ttcttttaca
    14941 cgtttttgaa tgagtcggca atactccatg acttttttgc ttgcttctgc atcatcttta
    15001 tccattcgat aaatagtggc ttgcatttct tcattcaaaa cgatcggcag cattcgattt
    15061 tcctttggca caatttccgt gatcatgttg ttgatcgcta aaagtagcaa atcacgctcc
    15121 ccaccgtgac tatcttctaa cagatcgatt tgaaccaaag ctgtataata gcagtcattt
    15181 tgagaactat aaccaaattg ctgcaaccgc tgatctagtt ctcgcctttc tactcgattt
    15241 ctaaataaac taagtacaaa tagcgtttcc agctgtggct tttgggtaac taagtgtgca
    15301 cttaacgctt ctttttctcc tatgatccga ctgactgatt gagcgaccaa atctagttct
    15361 ttcccactga atccttttga tttaagattc agacgttcct gtatttgaga aatcggacgg
    15421 gcaaatctgt ccgaaaataa gtaggaaaaa agaccaatga gtcctaccag tgttaaagac
    15481 actgcaacta gcccgattct cagattgcgg atcattgcgc caattgcact agagtcaact
    15541 tctaatctgt aaatccaatt attataatct gatttcagta ctatatacgt tttatctttt
    15601 tctcttatca ctttcagctg attgtaatct agatccacgt ccgttaatac agttggttgc
    15661 tctttatttt ttactgtctg agtagtaaaa aggttgccaa cttcgttttc aatagaaagt
    15721 atgtcttctc cactttcacc aacaacttgt tctattgtat gtttctctat cgtagcaatt
    15781 cccaatgcat atttttcttt ttcaaacatt ggcaaagaaa tcaccatttc gattcctttg
    15841 tttttctttt gccaaaataa attatttttg ttatttatgt acttctgttg atacttttca
    15901 acttcctctt cggtcagttg actcaacgat ccattgatta ctccccattt accagccaaa
    15961 ctgactaaat cataattatt atcatccata acaatcgttt ctataaaatt tagttctttc
    16021 ctgatttcag aataagtgga gtaatctgta tatgtcagcg gatgcttgaa tatgtccgag
    16081 aaatttttgg tcgaaccata cgtagaaaac gaatattcaa tcgttctaat tttccattca
    16141 acgttagttt taacttgcct gagcaaattc tttttgtctg ttaaataact cgattcgatc
    16201 gattcatagg tattctggta aatgaataaa ctaaatccta tgacaagtac ggctcctaat
    16261 aaaaacatcg gtaaaaatat tttataaaat actgtacttt tcttcatttt cttcctctcc
    16321 tccttttaaa ataaaaggct ttcatttttc tgtaaaattg atactcatct aattaaatga
    16381 gcattccccg ctttcaagaa tagcataatt aaaaataaaa atccaagtaa tttttaacgt
    16441 gtgcaatctt ttcatatcaa agatctattg acttatcgta gttatcgtaa tatgatgaat
    16501 gcgttaacaa aaagtgaaaa agtaaggaaa atgatggaat ggtaacgatc aaagatatcg
    16561 ctaaagcagc tggcgtttct catacgacag tttctcgtgc tttgaataac agcagtttaa
    16621 taaaaaatga aacaaaacaa aaaatacgac aactagctaa ggaaatgaat tattcgccaa
    16681 actatagtgc aaaaggttta gtgaatcaaa aaaaatatct aatcggacta tttttctcaa
    16741 gtttgcataa aggaacttca tcaaatttcc tagcagattc cattgcaggc atccattcag
    16801 tattagacac aaattacagt ttatctgttg aaagtatcga tgttgttgat ttaacagaaa
    16861 tcaacctgca acgctacgat ggactgatcg ttatgagtca aagtgatgat gatcagcctt
    16921 tcatcgacta tctcaaagaa aaagaatttc ctttcgttgt tgtcaatcgt cacatcaatg
    16981 atccagcggt tatcaacgtc actgccgatg atgcggccgg tgttatgcag gcagtagatt
    17041 acggtattgg atgcggacat acgaagatcg cttatattgg cggaaagaaa aattttcgtt
    17101 cgacaaaaga acgggaaaaa ggggtattga aaagtctaaa aaaagcgagc atccctgtca
    17161 atctagccta ttttttaaca ggagattaca gcttagaaag cggcctccaa aacatggaat
    17221 acctattatc actttctgac ctgcctactc tggttttttg cggcaacgac gacatagcga
    17281 ttggtgcatt gagagctgta catttagctg gcctccgtgt tccccagaac atttctctga
    17341 tcgggttcga tgattctcca gtcgtctcct atctcaatcc gccgcttacc accgtacgta
    17401 agcctttgaa agaaatgtgt caagaaggaa caaagctttt actagatttg atcgaaggca
    17461 ggacgatcga acaatctaaa attgagctct ccaccttgtt gatccttcgt gagtcgatca
    17521 attacttgta aactacaagt aattttatat aaaaatgtta acgtgtgcat aacacagaaa
    17581 ggaagtttat atgaaaaaac tgacaaaaga attagtgaaa aaaaacgaag cacctgtaaa
    17641 agttctttag tttggtgaag gcaattttat gcgtggattt attgattggc agattcagca
    17701 gctgaataac caacaattgt ttaaaggtaa tgttgcaatc attcaacctt tagaacaagg
    17761 tcttggaaat atgatgaacc agcaagataa tttatatacg gtcattttac aaggactcag
    17821 caatggcgaa atcgttgata cttccgagat tatcaccgta gtagaacaaa tgatcaatcc
    17881 ttatgatgaa tgggatgctt atctatctct agcagaaaat gacgacttgg cctatatcgt
    17941 ctccaataca acagaggcag gaatccaatt cgtggagact gataatttaa cagatactcc
    18001 cccacagagc ttcccgggca aactgacagc ctttttatac cgacgtttca aattaaacaa
    18061 agctggcttt accatcattc cttgcgaact gattgacaga aacggcgaac gtctaaaaga
    18121 aatcatttta cgctacgcag aaaaatggga tttagaacct gcttttgttg agtggttaga
    18181 aaaagaaaat gttttctgtt gtagtttagt tgatcgcatc gtcccaggtt atcctcgcga
    18241 agatgcaggt gttttcaatc aacggcataa ctatgaagat caattgatgg tcaaagcaga
    18301 accattcatg ctttgggtga tcgaagggcc taaagaattg gagaatcaac taccattcaa
    18361 acaggctggc ttgaatgtca tcatcacaga tgatatgact ccttatcgtg aacgtaaggt
    18421 gcatttgctt aatggaccgc atacagcgat ggtccctctt gctttgttgg cggaattgga
    18481 aactgtagaa gaagtaatga aagatccttt attctccgca tatgttgatc agttattcaa
    18541 tctagaattg attcctatgc tttctttacc taaagatgaa ttagccattt atgctgacca
    18601 aatcaaagaa cgtttcttga atccttttgc ccatcacaaa ttagaagcga tttcattaaa
    18661 tagtgtttca aagttcagca cccgtctgct tccagtgttc aagaagtata tcgaagaaca
    18721 aaatcaggta ccaccgttaa tcactgtttc actagctgcg ctacttctta tgtatcgagg
    18781 cgatcaagta aagccacatg atgatgaaaa gacgataagc gaatttactg atgcttggtc
    18841 tgataatgga acagctattc ctcgattatt gcaaaacgct gcgctttggg gagaagattt
    18901 gtctcaaata ccgaatgtga cagatacagt tcaagaaata gctgcaaaga tcgatcaaaa
    18961 aggtgtccgg tcagtattac aagaaatgaa aggaacgatg gtccatgctt gaaaccctgc
    19021 aaccaacaat gaaattaaat cgacgagaca gtgtggtcgt cgcattaacc cctattccaa
    19081 aacaaacaca actgacgatt gatcagcaaa cgatcaccac tcttgaagat atcccgcaag
    19141 gtcataagat tgcattgggt gatttgaaag ctggagacaa cgtgatcaaa tatggctatc
    19201 caatcggtca tgtgacgaca gacgtaactg ccggtcaatg gctgcacact cataatgtaa
    19261 aaaccaatct ttctggtgaa ttggattatc gatatgaaaa agatgtccat ccaagtcatt
    19321 acctttttga gaaccgaaca tttcaaggtt acttgcgaaa aaatggaaaa gtagggattc
    19381 gtaatgattt gtttttagta cctaccgttg ggtgtgtgaa tggcattgct gaactgatcg
    19441 tcaaacagtt caaggaaaaa catccagatc tgggacagtt tgaccatatt acgattttaa
    19501 agcatcctta tggctgttcg cagcttggaa aagatcatca aaatactcga gaaattttag
    19561 cggacgcagt aaatcatccc aatgccggag gagttttagt atttggatta ggttgtgaga
    19621 acaatacagt tcctgaattc aaaaaaattt taggtgaata tgatgaagaa cgagtgaaat
    19681 ttctagtggc tcaagatgtt tacgatgaga tcgaacaagg tgtggctcta ttagaagagc
    19741 ttttaacagc ggcggaaaat gaccagcgca tatcagtccc gctctctaag ttgaatgtcg
    19801 gtttgaaatg cggcggttct gatggtctat cgggaataac tgctaatcct ttacttggtg
    19861 cattttctga ctacttgatt gctcaaggag gcagcacgat cttaacagaa gtgccagaaa
    19921 tgtttggcgc agaacaagta ttgatggcac gagcggaaaa tgaagaagtt tttgactcaa
    19981 tcgttgactt gatcaatgac ttcaaacagt atttcttgtc ttacggggaa ccagtttacg
    20041 aaaacccatc tcctggtaat aaagcaggtg ggatcactac attagaagat aagtctttag
    20101 gctgcacgca aaaatcagga agctctcctg tcgttgatgt gctacaatat ggcgaaaaaa
    20161 tcagaaaacc agggcttagt ttattgcaag ctcccgggaa tgatcttgta gctgcctctg
    20221 ctcttgcttc atccgattgc cagttggtct tgtttaccac aggaagaggg actccgtttg
    20281 gctcatatgt cccaacggtc aaggtatcta cgaatacaac tctttttgaa cgcaaaggtc
    20341 attggatgga ttttaatgca ggcgtcttat tagaacaacc aatggaagta atcttagaat
    20401 cgtttgttca aaaaatcatc gctgtagcta gtggagaaga aacgaaaaat gaacaaaatg
    20461 acgttcgaga aattgccatt tttaaaaacg gagtaacact ttgattttca taaaacagta
    20521 taaaaagaaa gaaggaagat ttatgttttt atctgatgat tttttattaa aagacgattg
    20581 ggcgaaaaag ctttaccatt cctacgcaaa aaacatgccc attattgatt atcactgtca
    20641 cttagatcca aaagaaattt acgaaaacaa caatttcagc aatctgacag aagcttggtt
    20701 aggaggcgat cattacaaat ggcgcttgat gcgagcttgc ggcgtgcctg aagaaaaaat
    20761 cacaggaaat gcttctgatt ttgaaaaatt tttagcttgg tgtcaaaccg taccaaaaat
    20821 tatcggaaat ccgctttaca gttggtcaca tcttgaattg aagcgtttct tcggtattga
    20881 cttgttgata aatgaagaaa atgcagagaa aatttggaca caagcaaatg aaattttggc
    20941 agctcctgat tttcgccgtc gggaaatcgc aaaaaaatcg aatgtagaag tgatttgtac
    21001 aacagatgat cccgcagacg acttgcacta tcatcagttg cttgctcatg aagaaccaga
    21061 tttgaaggtt ctaccttcat tccgtccaga taaagcactc aatattgaaa aagaaggatt
    21121 taatgcatgg gtcacactac tggaagaagc agctgaccaa acgatcacca cctatcaaga
    21181 actgatagaa gtcttagggc agcggataga atacttccat caacatggat gtcgtgtttc
    21241 cgaccacgct ttagacatct tacgctataa agaagcggat gaaacagtat tagaagagat
    21301 ttttcaaaaa gcacgagcta acaaactatt atcttcagat gaaatcgatg cttatcttac
    21361 agaaacactg atacatttga cccacttcta tcattctcat aattggacga tgcagctgca
    21421 catccatgct tatcgtaact gtaatacaca aatgttggaa aaattagggc ccgataccgg
    21481 ctatgatgga atgaatgatc tttctttgac tattcctctg caaaaattat tgaaccgtgc
    21541 agaagaaacg gatcagttgc caaagacgat cctttattca ttgaatccga atgactatcc
    21601 tgcgatttta gctttgatgg gctgtttcca aaaagaacag aatggaaaac tgcagttagg
    21661 ttctggatgg tggtacaacg atactcgagc tggtatgcgc gatcaattga cacaatttgc
    21721 tgatggtagt gctttgggga attttgtcgg catgctgaca gattcaagaa gtttcctgtc
    21781 ctacactaga catgaatatt tccgtcgtgt tctttgtgaa tttttaggcg aaatggtcat
    21841 gcgaggagaa gcacctgaag atgaacaact tttaggaagt ctagttcaag cgattagtta
    21901 tacaaatgct aaaaattact ttggcttttt tgcctaattg attaatagta acagtaacga
    21961 atcaaaaaca ggatagtgaa ataacggaat ccgtttatcc acgttttaga gaagaagacg
    22021 gaccaaat
//
LOCUS       DAXLPC010000042        21998 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.042, whole genome shotgun sequence.
ACCESSION   DAXLPC010000042 DAXLPC010000000
VERSION     DAXLPC010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.042"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..1283)
                     /locus_tag="ACF3UE_001537"
     CDS             complement(<1..1283)
                     /locus_tag="ACF3UE_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3634946.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKG"
     gene            complement(1581..2516)
                     /gene="murB"
                     /locus_tag="ACF3UE_001538"
     CDS             complement(1581..2516)
                     /gene="murB"
                     /locus_tag="ACF3UE_001538"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFD3634947.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2589..3509)
                     /locus_tag="ACF3UE_001539"
     CDS             complement(2589..3509)
                     /locus_tag="ACF3UE_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3634948.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3622..4374
                     /locus_tag="ACF3UE_001540"
     CDS             3622..4374
                     /locus_tag="ACF3UE_001540"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFD3634949.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5238..5771
                     /locus_tag="ACF3UE_001541"
     CDS             5238..5771
                     /locus_tag="ACF3UE_001541"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFD3634950.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(6261..6785)
                     /locus_tag="ACF3UE_001542"
     CDS             complement(6261..6785)
                     /locus_tag="ACF3UE_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFD3634951.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(6778..7251)
                     /gene="tsaE"
                     /locus_tag="ACF3UE_001543"
     CDS             complement(6778..7251)
                     /gene="tsaE"
                     /locus_tag="ACF3UE_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFD3634952.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(7374..8354)
                     /gene="pta"
                     /locus_tag="ACF3UE_001544"
     CDS             complement(7374..8354)
                     /gene="pta"
                     /locus_tag="ACF3UE_001544"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFD3634953.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(8507..9187)
                     /locus_tag="ACF3UE_001545"
     CDS             complement(8507..9187)
                     /locus_tag="ACF3UE_001545"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFD3634954.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            9313..10182
                     /locus_tag="ACF3UE_001546"
     CDS             9313..10182
                     /locus_tag="ACF3UE_001546"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3634955.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            10208..10723
                     /locus_tag="ACF3UE_001547"
     CDS             10208..10723
                     /locus_tag="ACF3UE_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFD3634956.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(10770..11333)
                     /locus_tag="ACF3UE_001548"
     CDS             complement(10770..11333)
                     /locus_tag="ACF3UE_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3634957.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(11388..11567)
                     /locus_tag="ACF3UE_001549"
     CDS             complement(11388..11567)
                     /locus_tag="ACF3UE_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634958.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(11644..12153)
                     /locus_tag="ACF3UE_001550"
     CDS             complement(11644..12153)
                     /locus_tag="ACF3UE_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634959.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(12249..12629)
                     /locus_tag="ACF3UE_001551"
     CDS             complement(12249..12629)
                     /locus_tag="ACF3UE_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3634960.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            12959..13708
                     /gene="pnuC"
                     /locus_tag="ACF3UE_001552"
     CDS             12959..13708
                     /gene="pnuC"
                     /locus_tag="ACF3UE_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFD3634961.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(13892..15169)
                     /locus_tag="ACF3UE_001553"
     CDS             complement(13892..15169)
                     /locus_tag="ACF3UE_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634962.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15248..15892)
                     /gene="pcp"
                     /locus_tag="ACF3UE_001554"
     CDS             complement(15248..15892)
                     /gene="pcp"
                     /locus_tag="ACF3UE_001554"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFD3634963.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16091..17035)
                     /locus_tag="ACF3UE_001555"
     CDS             complement(16091..17035)
                     /locus_tag="ACF3UE_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFD3634964.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17037..17723)
                     /locus_tag="ACF3UE_001556"
     CDS             complement(17037..17723)
                     /locus_tag="ACF3UE_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFD3634965.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            18197..18517
                     /locus_tag="ACF3UE_001557"
     CDS             18197..18517
                     /locus_tag="ACF3UE_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFD3634966.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            18671..19576
                     /locus_tag="ACF3UE_001558"
     CDS             18671..19576
                     /locus_tag="ACF3UE_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3634967.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            19573..20346
                     /locus_tag="ACF3UE_001559"
     CDS             19573..20346
                     /locus_tag="ACF3UE_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFD3634968.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(20527..21951)
                     /locus_tag="ACF3UE_001560"
     CDS             complement(20527..21951)
                     /locus_tag="ACF3UE_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFD3634969.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
BASE COUNT         6497 a         4478 c         3853 g         7170 t
ORIGIN      
        1 cctttcactt gagaaataat gtaatcggta taagcagatc cttgcgaaaa atcaatacag
       61 acatgaatcg gtgcttcaaa atatgatacc ggacaaatac cgaccaataa aaagagataa
      121 tcataaaata agcgaatcat gaaacgttca tcttttccca agaaatagcg tttattctct
      181 tgtatgacct tttggattgc tgtactgaat attggatacg tctcgaagaa aaactgtagc
      241 tgctttttag acgtaaagct agtcatctca aagtcgaata tccaattttt tcgattgaca
      301 tgcatcatac ccatacgaag ttcttttcgt atatatagtc tttcttcttc agagatttca
      361 atcgaaaatg gtaattgatc aatcaattcc actgacattt tttgactaat catgtggata
      421 tcatgaaaat gagcttccgc aagtccaaat gcgccatcta attcaaattc ttcttccgtg
      481 atcaaaaaca acatgatata agaaatctca tcaatgatct gctctttagg gatatgaaga
      541 aaagaaatat gtgataaatc cttgatgatc ttcattcctt ctgagctctt aaagtattca
      601 tctgaaaaga aacgttttcc gattggttga ttcccatagg ccctcaacaa actaatagtg
      661 gttagcaaat tgaatttgat tcgttttgtt gcagacagtt ttaaattgaa cagatattca
      721 aaatattgca cgatactctt tgcttcattc atgacgcttt ctctaaatgg catagaaaaa
      781 ccattaaaga ccccgaaata taccccaaat aatacgttcc gtatgtttat ttcttcccca
      841 actaatatgt ttttctttaa ctttatttga tgctgttcaa gaaaagagac taattctctt
      901 ctttttacat aggctcttga tatgcttaaa aaatgattct ctgcaaattt ttcgatcgtt
      961 acttttgaat ccacgatctc cgttaacagt cgagcaattt ttgatcgttg aaagtagatt
     1021 cttcttaaat ttttgatatc cgtcaaattc agacgttcga catggatctc tgcttcttct
     1081 gaaatttgga tctctggctt tgttttgaat tcagtaaatt ctttatttaa ttctatgata
     1141 taatttcttg ttttaaattt agacaaacct aatgtttcat ataacttagg cagcactaca
     1201 taattctttt tctcaaattc taaatatcta gctagcagca gtttttctct atcttcctct
     1261 tctataaggt aatccaactt catatcctac acctcaaaaa atgcctcata ccaattactt
     1321 gatatgcaga tgaaagttca tcttttcacc tatactgatt ttatgatgga ttatgcttgt
     1381 tttttcatca gttattctca ttttttatct tttttttgag aatattgcaa aaaatggaaa
     1441 aatttatgag gaaatattct atattttttg ttttattgtg ttaaaatgta caagatttgc
     1501 gccatttgcg taaacaacca caaaaaagag caggacggcc accgtcctgc tcttttactt
     1561 attttaagtt ccattactta ttaattggct aaacttctgc ttgtttctga tattgcttgt
     1621 ttttctccaa tgatccgcac ttctgtttct aaagacacat caaatttttc tttgattact
     1681 tcttggatgt gcgcaatcaa ttcaatataa tctgtcgctg tcgcatgatc gatattgacg
     1741 atgaatccag catgtttttc agagacttgt gcaccgcccc atttcaggcc ttgcaatcct
     1801 gcttgttgga tcagctgacc tgtatagtgt cctactgggc gcttaaagac acttccgcat
     1861 gaagggtatt ctaatggctg ttttgattga cgcaattcgg tcaactcatc cattcttgct
     1921 ttgattgctt cataatcccc tgtttgcaaa ctgaatcgag cttccaatac gatagcacgt
     1981 aattcttgga ctttactgtg acgataagaa aataccattt cgtcttttgt caaagttttc
     2041 aatgttccat cttcaagcaa aagatccact tcagcaaaaa catctttgat ctctccgcca
     2101 tacgcacctg cattcatata aaccgctcca ccgacacttc ccgggatgcc gcaagcaaat
     2161 tcaaatccag tcaatgattc tgccaaagct gcataagtcg tatcaatcag tgaggcacct
     2221 gcttccgcaa tgaccatcgt tcctttgaca tgaatctgtt tcatttcagt cagcatgatg
     2281 actacaccgc gaatcccgcc atcttgaacg atcagattgc ttgcatttcc taataccatc
     2341 caaggtatat catggattcg gcaataatcg atgatttgct ttacttcttc ttgttttttc
     2401 gggaatgcaa ggacatcagc tggtccacct gttttcgtaa acgtatagtt catcaatggt
     2461 tcatcaaaca atatagtaat cgtggctaag ctttcaacta tttcttcttt attcactgag
     2521 gattttcctt tcttttctca aacgtcctca ttattctatc acgcttaata caatcttgcc
     2581 agtcttgttc aaagttgatg acggtagtga tctttaagca cttcctcaca taattcatga
     2641 cttcttacaa cttctttttg tttaagcaat tctgtttccg atttacctaa acggatctga
     2701 gaaaagaagg cctctaccat tggctcaaac ccgcgtttga ctagcgtgtt tgtccagtcg
     2761 ccaaattctt tcactttttt tccatcagca tcttgaatga caagctgggt cagatcgttt
     2821 acttcataag taccattttt acttgttact tgatattttt ctatattagc gccacttgct
     2881 aaatccatcg ttaaaatagc cgtttgattt tgtgtttcta attgtaaaat ggcatattcc
     2941 aaaaattcct ttgtttctct tatctggtat tttgttctca aaatgggttc atctaataaa
     3001 tacacagctg tatcaataag atgtaaaaac aaatcataaa ggacgaactc tgtcgtttct
     3061 tttgccgcta ttcgattttt ttgcaggtgg atcaaccgct tatctgggat acgtttcaat
     3121 tcttctacca taggagcaaa gcgccggttg aaaccgatca tcaaaattat ttggttctta
     3181 tcagctaatt cttgcaattc acgaacttca tttagatgga cactcagtgg tttgtcaata
     3241 taaacatgga taccattttc tagacatttt ttggctaatt cataatgtac ttttgttgct
     3301 gcgtggatca tacatgcttc gattttttct tctaaaagct catcgatcgt ttcatataga
     3361 tgttggaacc cgtactcttt ttgaattctt tcttttgttt ctttatttct tgttgcaaaa
     3421 taaaaatcaa gtgttccttg ttttttcgca taagttggta aatatgcttt ttctgcgata
     3481 ttccctacac cgattacacc aatcttcatc tactttcctc ctggatcatt tagttacttt
     3541 catcttacac cattttttac taaaatgagg tacaatagta tcgcaaaggt aaggaaatta
     3601 attcgaagga gtgtgctttt attgaaattt atctcttgga acgtaaacgg gcttcgtgcc
     3661 atcgtaaata aaaatttttt agaagttttt catgagttag acgccgattt tttctgtctg
     3721 caggaaacga aactccaagc aggacaaatt gatttagatc ttccaggtta ttatcaatat
     3781 tggaattacg cggaacgaaa aggctattcc ggcacagcga tttttgctaa aaaaccagca
     3841 ttgaatgcca cttacggaat gggtatcgat atccatgata cagaaggccg tctgattact
     3901 ttggaatatt ccgatttctt tcttgtaacc tgttacacgc caaattctca aagcgaatta
     3961 aaacgtttag attaccgatt agaatgggaa gaagcctttt ataattattt ggaaaatcta
     4021 aaaaaacaaa aaccagtcat cgtgtgtggg gatctaaatg tcgctcatca aaagattgat
     4081 ttgaaaaact ggaaaacgaa tcaaaaaaat gctggattca ctccagaaga aagagcggct
     4141 ctttctcgac tgttggataa cgggtttatc gatacattcc gttattttta tccaacccag
     4201 gaaggtgtct actcttggtg gaactaccga ttcaattcaa ggaaaaacaa tgctggttgg
     4261 cggatcgatt actttttgac gagcaaagat ttagagccag gactagctga tgcaaagatc
     4321 catacggaca ttatgggcag tgatcattgt ccagtagaat tagatttgaa ataaagaggt
     4381 tgtgaaaaag tcgtttagtt tcgagtatta agaaaaattt tgtgaaaatg gctttccaca
     4441 ttttgcataa atttggcata ataccgagaa actggctttt gaacactgtt tatcgagaga
     4501 ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc aaacaaaaat agttcctcat
     4561 atttttcgtt tggttgggct tattaccgca gatacaagct tttgaacacc gtttattaag
     4621 aggttgtgaa aaagctgcac tgcatcaagt aataagaaca gccaaacaaa aatagttcct
     4681 catatttttc gtttggttgg gcttattacc gcagatgcaa gcttttgaac accgtttatt
     4741 aagaggttgt gaaaaagctg cactgcatca agtaataaga acagccaaac aaaaatagtt
     4801 cctcatattt ttcgtttggt tggacttatt accgcagatg caagcttttg aacaccgttt
     4861 attgagaagt tgtgaaatca gcgtcctgac ctgagtatta gagaaacaaa tggcaaaata
     4921 gttcctcata ttttgctatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt
     4981 tagtggagaa gttgtgaaaa agtcgcctac tttcgagtcg taagaaattt ttttgaaaat
     5041 ggttcctcac aactttgcat aaatttgact taataccgag aagtcatgat ccccatctaa
     5101 ctccaaatca caaggaatga gttcaaaaac tagcttttct caacaaatat tacataaaaa
     5161 attctatgtt ttttgttaaa tttatttgct tttttcaaaa gtatgttaca gtaatttccc
     5221 aaggaggttt tacagaaatg aattttgttg ccatggattt tgaaactgcc aatcatcagc
     5281 cttatagtgc ttgttctctt gcgctagtca tggtaaaaaa tagccagatc gttgatgaat
     5341 tctatacatt gatacagcct gagactcctt ttttctggcg aaatgtccaa attcacggaa
     5401 tccatcaaga agacgtacgc aatgcgccga aattcccaga agtctggcaa actatccaac
     5461 catattttca aaaaaatcgt ttagtcgttg cacataatgc tgcttttgat acaaaggtct
     5521 tagcgggatg cttagattat tatcatcttg aacagcctaa ttatctttct ttatgtacag
     5581 tgaaaagtag ccgtcgcctg tttcctgaat ttccaaatca tcgattgaac actgtgtgcg
     5641 aaaatttgaa catccaatta gatcatcacc atgatgcatt ggaagatagt cgtgcatgtg
     5701 cggaaatcct gctttatcaa gaaaaaaaat tcgggacaga tccattgaaa aaacttgtga
     5761 ctataaagta aaagaatact tatgaaacac acaaagaggt cgtgagcctg ccgtttcact
     5821 ccgagtcaca aggagcaatt tcaaaaaata gcttctcatg tttattaaat attgtgactg
     5881 gtgaccgagg agctggcagg agaacaccgt ttattggaga ggttgtgaaa aagctgttct
     5941 gcatcaagta ataagaacag ccaaacaaaa atagcttctc atatttttca tttggttgga
     6001 cttattaccg cagatgcaag cttttggaca ccgtttacca agaggttgtg aaatcagcgt
     6061 tttgacctga gtattagaga aacaaacggc aaaatagttc ctcatatttt gccgtttttt
     6121 gagctaatac cgaaggtcag ctgattgaac accgtttatt caaaaaaaat ggactgcgac
     6181 acgacttttg tcacagtccc ttcgtgtgtt tttctgcctt ctcaaaagga tgacagtttc
     6241 tcactctttt cctatttctt ctattcaatc aaataactca ttttatatac atctaaaaat
     6301 tcacctagat ctgttcttgc ccctctaggc atgaccgctt cgatttggaa gcccattttt
     6361 cggtaaaggt gtacggctct ttcattacga acttgaacgt caagctccaa tcgaaaaagt
     6421 acacccattt ccttcgccca actgatgatt tcttctagca taagagtgcc tagtcccatt
     6481 ccccaatatt cctgcagaat actgataccg acttctccca cgtgagacaa acgaaattga
     6541 ctgtctgcct tgacagatgc tgttccaata atcgtccctt catagattgc aagcagcaat
     6601 aaattattat tgctttcgta tatataatcc aactcttctt ctaaggtttc tggtggtaac
     6661 aggagttctg cttcatccaa aactaaaaat tctgtctcct tattaacttg tcccatcatc
     6721 aaaagaatgt cttttgcatc tcctggcact gcttcccgca agatgatccc aacttcttca
     6781 ctcatgattt tcagcccatt tttctagaat tcgctgtttg aaggtttcac tttgctcccc
     6841 gtatgagatt agtttcacat accgcttttc taaatctgta tcactttttt ctaaaatcag
     6901 ttccaaataa tcctccggca gtgcttcttc taatagattt ccccattcaa caacggaaag
     6961 cccatcacct tcaaaatatt catctaaccc taaatctgct ccgctagctg ctacccgata
     7021 aatatccata tgatacaacg gaatccgacc ttgactatat tctctaataa tcgtgtatgt
     7081 cggacttttg atcatttgcg ttatccctaa tccttgggca attcctttcg tcaacgttgt
     7141 tttacccgca cctagatcac cagtcaatat cagattgtca cctggcattg cggaatgacc
     7201 aattgcctct gcgaattgtt ctgtcattgt taatcctgat agttcgatca tttttcatct
     7261 tctcccgctc ttctttcttt ttgccagtat atcgcgtaat gaagtttttt taaagaaaaa
     7321 atgaactagt caagaacagc agctgctgtt tttggctagt tcgcgtgtat ttgttaatca
     7381 atcaatgttt gtgctgctgt gataatcgat aatttatata catcttcttc atttgctcca
     7441 cgagacaaat cagaaaccgg tttgttcaag ccttgtagaa ttggtccgat tgcttcaaag
     7501 ttaccgaaac gctgagcaat tttatagccg atatttcctg actgcaattc tggaaataca
     7561 aagactgttg cttgaccagc tacttctgaa tctggcgctt tcagttgtgc aactgaagga
     7621 acataagaag catcaaattg caattcgccg tcgatcatgt attgtggcgc tagtttttta
     7681 gcgattttag ttgcttcaac tactttgtct acttctggcg atttcgctga gccttttgtc
     7741 gagaagctca tcattgctac ttttggttcg atatcgaaca attctgctgt ttttgcagaa
     7801 tctacggcga tttcagccaa ttcttgcgca gttggattca cgttgatcgc acaatccgaa
     7861 aagacatatt tttcttgatc tcttccacgt accatgatca tcgctccgct tgtccgactg
     7921 atgccaggct ttgttttgat gatctgaagt gctgggcgaa cagtgtcgcc agtcgaatgg
     7981 atcgctccag agaccattcc gtctgcaatc cccatatacg taagcatcgt accaaagtaa
     8041 ttcacatctt ttaaaatctt ttctgcttgt tctttggatg cctttccatt tctacgttca
     8101 acaaaagtat ccaccatttc atcccactta tcgtaattat cagggctgat gatcgtaaag
     8161 ctagatgttt tgattcctct ggcatgcgct gcatttctta tttcttcttc gttccctact
     8221 aaaatgggtt ccacaagttc ttctgctttc aaccgggcag ctgcgcctaa aatacgagca
     8281 tcagtagctt ccgggaaaac gattttgatc ccacggcgaa caattttaaa tcttaaacta
     8341 tcaaacaatt ccacaagatg acctccagac gtttttatat gtattatcat acactattcc
     8401 agaaaaaaag aacagtttat tttatctgta tcagtcaaaa atgctggaaa aattaagttt
     8461 ttcacataca aagcgaactg cactataaca ggaaagcgct gttttattac actgtttcag
     8521 gcagttgcca atcaatcggt tcttctccta acgcaaggag cgcatcattc gttttcgaga
     8581 agggtttgga accaaaaaag ccacgacttg cagataacgg actgggatgt ggagatgtta
     8641 tgatgatatg gcgactctta tcgatcattt tgattttttc ttgtgccggt tttccccaca
     8701 agataaacac gattggtttt tcccgttcat ttaatttttc aatgatcgtg tctgttaatc
     8761 tttcccaacc tttcccgcga tgagaatacg cttgcccttc ccgaacggta agaacggtgt
     8821 tgagtaaaag gactccctgt ttagcccatg acactagatt tccatgttga acaggtgcga
     8881 ttccaagatc atcataaagc tctttataga tatttcttaa cgatggcggg atctttacgc
     8941 caggttgcac agaaaaagat aagccatgag cttgattttc tccatgataa ggatcttgtc
     9001 ctaaaatcac cactttaact tcttcataag gagtcaattc caatgcttca tagatatgat
     9061 acatatctgg atggatcttt tgggacgcat attctttttt taaaaattct cttagatgca
     9121 gataataatc ttttgaaaat tctgaggaca aaacttcttg ccaactgtta tgaatgattt
     9181 ctttcaaaaa ctccacctcc taataaaaag aataactcac attttcttca atcacaaggg
     9241 acaatcttca ccctcagcac ttgattaata tggtaaacta ggaacaagaa gcagaaagga
     9301 acgataatca ttatgatcaa attaattgca tcagatatgg acggcacatt attagatgcc
     9361 catatgagtg tttctcctga aaatgccgag gcgatacgtt ttgcaaatga tgccggtgtt
     9421 gagttcatgg tcgctactgg tcgaaactat caagaagctc gcgcagcttt agatgaggta
     9481 ggaatcgatt gtgcgatgat cactttgaac ggggcacagg tatttgataa agaaggaaat
     9541 tcattgttta ccgtgtcgat tccaaataat caagcaatct ctgttttaga tattctagat
     9601 gctaacggta tttactatga agtagcaacc aacgatggtc tttattctga aaatcaagcg
     9661 aaacgaattg aaagttttgc ttccatggtg gctacccatt tacctcacct tacgtataaa
     9721 atggcgattg ccatggcctc agctaagctg gagttattgc acatcacata cgtggacagt
     9781 attcgtgcta ttttggaaga aaagaatctg gaagttttaa aaattatttg ttttcataca
     9841 gaagggccag ctgtattagg tccagttgga aagcagattt ctcttttagg cgatctagcc
     9901 gttacttcct ctggtcaaaa caatatcgaa gtgaaccata aaaacgctca aaaaggaatt
     9961 gctgttgccc atgtcgctca cgagcgtggg atttctttag aagaagtcat gacgattggc
    10021 gataacttca atgatgtcag catgctgcaa gtagcaggag tcagtttcgc aatgggaaat
    10081 gcagaaatcg aagtaaaaga ttatgccaaa tatacaacgg acacaaacct tgaatctggc
    10141 gtaggaaaag ccatattgcg cgcgattgca gaagacttgt agttttatct agaaaagagg
    10201 gatatagatg tcagaatttt tcattcagga aaagcagctt ggacgtgcaa ctcggacaat
    10261 tgtcaaaaac gaaaaaggac attccctgtt tttgatggtt ggtcgctggg gaacaaaggg
    10321 cgatgcattg tctctttatg ccatgaatgg cgatctcgtt gctcacatca agcagataag
    10381 cctgacattc ggtacgcgtt ttgagctgta taaagagttc gaaaaggtgg gaaccatgca
    10441 gaaaatattc aattggcccg gtgactttta ttatattcgt agacttcact ggacagtcca
    10501 aggtgatatc tataatcatc aatatcaaat ccatcatttc aatcagcaaa tcatgaaaat
    10561 ggataaagca acactttttt caggagatta ctatgtattg gatgtctcaa atgatgaaga
    10621 tgctccagtt tgtatttgta ttgctgcggt tttagattac tggctctacc gtaaagacaa
    10681 aagtcgcgat aagcctgttt cttaccgact taacttaagt taaaaagatg tacctgaaat
    10741 gcggaaatac gcatttcagg tacatctttt tagatattct tttgcatatg atcataaaga
    10801 tgaccactga tcatccgctg accgacaact ttgaagtcat ggcgttcgta taatttttta
    10861 gcctttggat ttttttcatc cacacttaga ccgatgacgg agcgattagc tttcttcgcc
    10921 aatttaggta atgcttctaa taatcgcgaa ccgatgcctt gtcctctaaa atcttctgat
    10981 acactgatag agtccaaata ccattcgttg ggaaacgttt ctttatcaat gaacaaacgt
    11041 gtagacgcat ctagctgata tttctctaag ataggtacca gtggctgatc gatgattgat
    11101 tcttcttcat ctgtataacc gtaagcaact cctgcaactt taccgtctat ttcttctacg
    11161 atacctcgtg aataactgta acgataattt ggatcagtga ttgcttcttc taaaatctct
    11221 aaagtctttt gttcccctgt ctgcttcaaa aatggcagtt ccatatcttt tagaatcact
    11281 aagatcaatg gggcgatttc tggagcatct tcttttctcg caaaacgaat catagtttcc
    11341 tctccttttc tccattctaa catgcagaaa aagaaatcgc aaaatcgtta ttttaaaaaa
    11401 tcttcaatct tttcagtaat gaaataacca tgagtaacga ttcttgccgc ttcagttcgg
    11461 caataagggc agacgactgg catttcttta tcattatgtt cgactacatt attgacttct
    11521 tcgtatgcaa atttttttcc gcaattaggg catttcattt tttccatgtt atctcaactt
    11581 cctttcatct ttactctctt agcttactct tatattgtaa aaaagagaag caatatcctt
    11641 cttctatgca gatatccata cctgacggtc ctgttctcca tctattaatc ggactttata
    11701 ataaggacgt tcatctttga ctagaagtgt ccactctttc acttttgctt ttttcccgta
    11761 gtagctgact gcttccttca tcgctgcttg cggttgtttg aactcttccg ttttttctat
    11821 atcaaaaaga tgttctgcgg ccttttccgt gtcatttcgt acggttgttt tcccagtgga
    11881 tggattgact gctatgactt gtccttcaca aaaaaactgg tattcatatg ttgcattcgt
    11941 aggattctcc aaatcttttt caactgcaaa atgaatagca gatatgttat gttcttttgt
    12001 ttcgtttttt acgattgctg ctgctttttt caatgagatc cgatattcct ggtcactaat
    12061 atcatccatg tgaaaagcgg cattgagcag tcccgtcata ccggtaatcc ctattacgat
    12121 gagggcagca acaccaaaca tcattttttt cattcttcat tctcctgttt ctttttttta
    12181 aagaatatca agaaatgaac gaatgaaaaa tcgaatgaaa cgaaaaaaaa gtgacaattt
    12241 tgttatcttt attcgtgcag ttctaatggc aatccgtctg gatcaaagaa aaacgtcatt
    12301 ttttttcctg taaaggtatc ttctctaatc ggttctgatt cgatccctaa ggactgcaat
    12361 tctgcaattg tttcttcaat atcgtctact ttgaaagcaa gatgacgcaa gccacaagct
    12421 tctggatagt ttggtcgttg tggcgcatta gcaattccaa aaatctccaa ttcagcactt
    12481 cctagtttca gatctaattt atagtcatct cgttctttgc ggtaattttc tctgattact
    12541 tcaaatccta atttattaac ataaaaatca cgtgatttct gataatctga aacaatgatg
    12601 gctatatgat ggatcgttgt aaggttcata tgagcactcc tattcttcgt ttaagctcgg
    12661 atctatatta atctccagtt ccattgtaaa tgtgtcagat tgaaaaaaat agctgttttt
    12721 cctttttata agaaaaaagg caaaaaaaac agaaagtagg tcctccaaga cactcttcct
    12781 gttcccaata taataaatga aagtaagaaa ttatattttc aagaaaacaa acagaaaatt
    12841 atcataacac aaattattta taattgaaag actagttttt tttcaagaaa agcatacaat
    12901 agattgtgtt agtaaataca gaacacacta catttagtgt cttaaggagt cctcatacat
    12961 gaagtcatat tttcagtttt tagctcatca gctaaaaggc tggccgcaac aaaattatta
    13021 tcttttcttt ttcagtcttg gctgccaggt catgactctt gtcaatagtc ccatcacttg
    13081 gctgtccgtt attacattta tcggtaccac gcttggtgta ttgtgtattt tatccatcaa
    13141 tgcggcaaaa tcagtcaacg gtattttagg tattttgtct gcgatttgtt ttattatcgt
    13201 tgggttttca gcaaagaact atttaagtat cggtgaacag attgcttata tgatcacatt
    13261 ggatatcccc gtattgttaa gtaaagaatg gaatcataat atggcttcaa aaatccgaaa
    13321 attcactgga aaaagctggt ttatcgcaat catcagtact ttccttgtct atcttgtttc
    13381 aggattcctg attggtcgtt atacagatga tcctcggccg tgggtagatg ccattgcttt
    13441 ttctattagc ttgactgctg gtatcatcag tttcttgcgt tacaacaacc aatattactg
    13501 gtggttagct tcagggcttg ctcaaatggt cctttggtat atttcattta cgcatggatc
    13561 tgcaagtttg gcgatgttcg tgaacagctc tgtttacttg ctgaatgatg tccttgcatt
    13621 taccgtttca ccttggtata accaaaaaga acgtgaacgt atgcaaaaaa tggaagaaga
    13681 atactacaac gcacaacaac acgcataaaa aaactgagcg tgggacaaaa gtaaagaaca
    13741 cttttgtctc acgctctaaa cacgtataaa cggcggaatc agaagcaact ccttcggaaa
    13801 taagctgaaa ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg
    13861 agttaaacgc ttctgtccca gcctctattt tttatagtaa ttccttcaga tactttcttg
    13921 cctcatcatt gaaacgcagt gattcttcta acttctgata atattccaac gcttgtttct
    13981 gagcttcagt aaaacgataa tgttttcctt tccatttgtc gattgtctct tgcacatttc
    14041 cagattggat atctttcact actagttgcc atttttcttt tgagactgta cggtctttct
    14101 tatcagcaga ttgtatagct tctcgttctt tacgcaatac ttttaaaaaa ccatttctga
    14161 ctatccgagg aatgctgtcg aagaaccctt ctgtaaaacc atagcgacaa tattgcttcc
    14221 aaataaatag atagattttt ggttggatga atcgttggtt tttcgcaaaa tattccatct
    14281 gagcagtgac ttctggtgtt cgttgacgtt ttgtctttct caacacggaa ataaatgttt
    14341 caaaataagc attaggatgt actggcactt cttcatatac gatggattgc caatctttac
    14401 gtaaaaatgc gcgatagttg atcaagaatt cttctacatc ctttactaat tcttctgcaa
    14461 agtcgtcaaa tagttctttt tttatctgtc gcttttttga ctgcccattg atgtgttcac
    14521 ttattttctt gatttcattt tccaatgctt gataatccgc tatgtaaatc ggcatttcta
    14581 cttggcgaaa ttctgcgagc cgctgagcta attttatatc cggtaaatat ggctgtttca
    14641 tccgacgatt ttggtacaag acaaaacagt atttttgcca tagtccttca ggaaaatcga
    14701 tattcttctg cttaagccat aataattcgt ctaaggccag atcaactttt gtcattccct
    14761 gatggatcga agctgccact gtcggagaga catgcaggtg atcggcaaag tggttgatgc
    14821 ctagttttag gatctttccg gtttttggcg atttaacgat gtattgcact tttaattctc
    14881 taccacactc acaatacaat ttttgctggc ttcgttttgt tcgaaaaaac ggattgatct
    14941 tgaagtcaga aaacacccaa tctgttgcag ctaaataatg ttcttccata aaacgagagc
    15001 tgattagata tcggcggtgc ttatcgacta gttcccgctg ttttttcgtt aattttgcat
    15061 agatctccca acgttgactg cttgtgtatt gtttagaaat tttgatggga tagcttttgc
    15121 tgatttcttt tggaaaccat tcttcaaaga cggattgcca ttcttccacg gctgtttctt
    15181 tcctttctaa ttacaaaaag ctggctacta acataacgtt agcaaccagc cagtgtttct
    15241 tgctaaatta gtgagttgtt ccggcatttc cggaaatatc ttctttattt tctactgctg
    15301 cttcaactgc ataagtcaaa gaagaagcaa tgtcttctaa agacatagaa ggcgtaccca
    15361 ctggacgatc gatcacttga tcgggtgaga atggcacgtg gatgaaccca cctcgaattg
    15421 ccgggaattg tgtttcgatc aaatgaagca aacgatacat gatatcattg cagacaaatg
    15481 ttcctgctgt ataagagatg tacgctggta gaccatgatc ttgtacattt tttgtcattg
    15541 ctttgattgg caatgaggta aagtaagcgg ctggaccgtt ttcttctaaa gccgtatcga
    15601 atggctgatt tccttcatta tcagggattc ttgcttctgc tagattgatt gcgacacgtt
    15661 cgaacgagac tgctgaccgc ccacctgctt gtccgacaca gatcacgaca tctggttggt
    15721 gctgttggat ggcttctttg actacttgac tgcttttttc gaatacggtc ggtacttcca
    15781 ctttgatgat ttcagcaccg ctgatttcat ctggcatttt ttttactgct tcataggctg
    15841 gattcacttt gtccccacca aatggatcaa aacctgttac tagtactttc atctgttgtt
    15901 cctccgtccg attgatttaa catatggtta tcttttatca taccattttc cttgaacagc
    15961 gtaaataaag gaaacaatag tttaaataac ataacagatc aaacttaata tattcttata
    16021 aaaaaatagt gttccactac aatgttagaa gaggttgcga caattattct gtcacaaccc
    16081 ctctcttcta ttatttaaat agaatcatat aagcaatttg gaaaactagc ataaataacg
    16141 caataaacaa ctggtttttg atcactccgt atttgtcttt catctccagc atcgctacag
    16201 gcacgatatt gaagttagca gccatcggtg tcagcagggt cccacaaaaa ccgcaagtca
    16261 atgcaaccat tcctattaac gctggattcg ctccatgact aaatacgaat ggtgcaccga
    16321 tcccaaccgt catcacggtg atggccgcaa atgcattccc catgattacc gtaaatatca
    16381 ccatgccaag agcgtaaatg atgatgccga tgttcacatt tccttctgga acgatcgtac
    16441 ctactgcatt ggaaatcact gtcccaactc cagcgcttgt aaataccgca cctagagaag
    16501 ctaaaagcat tggcaacatg cttaacggcc ctactgtgcc cagcatatct gctgcatcat
    16561 ctaaaaatgt acttggtcga ttatctcgag aaaagaacat caagattagc atggctgcaa
    16621 aaacaccgac gcccacgccg actaaagcac ctaaattggt aaatagagca aacaagatcg
    16681 caaagacacc gatactcaaa gctggaataa aaattttcat tcctagtttg tctgacattt
    16741 tttccatata ttcttttgat ggaagccggc tttctccttt gctgactttc ttagcaattg
    16801 ctggtatggt catcgcaaag atcaagccac cgttcacgat tgccggaagc catcttcctc
    16861 ctgcaataac tacccctaag accgtccaga aaaaggctga cccataacga tgaggattgg
    16921 ttttatctgt taaatttctt actccagtgt aaatcaatac gagtcccatc acgatataaa
    16981 ggatctccag taatttatcg cctaataaaa tatcaggatt tgtaaaaaag tccatcttat
    17041 tgcccctttc ctggataata tttcttcgct aatttctttt ctttaagata gaagtagaca
    17101 cttgccacaa ctaaagccgt gatagccact ggaacttcca ctaaagcaag ctgtcccaat
    17161 gttacgtcat atcctagatc tttcagtgtt gattggacta gcaacgcccc tgctcctccg
    17221 atgaatagta cttggccaaa gaaccagcag acattttcca tagctgaagc catacctttt
    17281 agttcttctt catgcttagg atggacttct aacccttttg attcgatggt ccccaatgcc
    17341 atcggtaaaa tgattggacg aacaaatcca gcaactccac caaaactcac gttaaaagcc
    17401 gcaaagatca ttcgaaagat cccataaata tctacaatca taccagcaga tactttcttg
    17461 aatcgcttga tcaaggaagc cgctgattct ttcagaccat ttctttcaag cgttcctgtt
    17521 gccaacataa tgatgataaa aatcgccatc ccgcgattgt ttacaaaact tgtacctaaa
    17581 agttctaaca ttccttgaat gccaagaccg ccagtcaaag ctgtaacaac taaagcaacc
    17641 attacgatca atatcgagtc taatttaaat gcaaacccga gaataacaat caagacgcct
    17701 aaaaggctaa gataattttc catatatttt cctccataaa atgacaatat ttttttaatt
    17761 ataaagcaaa acacataaaa aatatagttg ttttctcacg aaatagacac tatttttaaa
    17821 tatttttcgt tattttttta tcacaaaaat tatcttactt attgtaaggt aaagcttttt
    17881 ttaatttatt gcccgataat atatagaaat aaggtctagt tactgttttt tttaaatgat
    17941 taataaataa caacttcttt ctatgaaatt gcaaagcatt catcttcttt tccgctaacg
    18001 atatatccgt cagtgcttgg tacactttac taaaaagtat gagattgccg atatctggat
    18061 aggtgtgcta tactacagaa aaagatatac aatctgccac cgggtaggat aaagaggatg
    18121 atcattccat taggtctttg aagggatgat tttcctcttt ttgtgtattt ttttatagtt
    18181 aaggaggaat gtaagtatgg catggatgga attaatcata gcaggaattt tggaagtatt
    18241 ctggtcaacg atgatgaaat ggagtgatgg tttttctaaa atcaattatt ctttttacac
    18301 agtgattggc atgattgcta gtttttactt tttgtcaaag gcaatcaaaa gtttgccgat
    18361 gagtctctct tatcctatct ggacagggat tggcgcagtt ggttcggtca taattggtgt
    18421 ggtcttgttt catgataagc tgaatctttc cacttggttc tttgtgggga tgctactcat
    18481 cagtatcatt ggcatcaaga ttactagcgg ccactagaca cttggaataa gtactgatca
    18541 gaaaaaataa gcctttttat ttaatattca atttttttat gaaaaaataa gaaataagtc
    18601 caatgaccta gcgacttctc cactcatcag gtgtatgctt gtactatcta tagaaaagga
    18661 gtgaatattt ttgaaaagtc tttcggtcca agaattatcc aagaactttg gtcacaaaca
    18721 agccctcagc gatgtcagtt ttagcttatc ccctggcaaa atcgttggat tagtaggtcc
    18781 taatggcgct ggaaaaacaa cgatcatgaa agctatttta ggactgatcc attactcaga
    18841 tggaacaatc tgtattggtg aaaatgagat ttctccctct agtcataaag ggttggaaca
    18901 agtaggagca ttgatcgaat acccgggtat ctatccattc ttaacaggct atgatcatct
    18961 gaagttattc tctgaaacca acgatgtatc tgctatcgac actatcgtga atcagctcaa
    19021 gatggaaaag tacattcaca aaaaagcgaa atcctactcg ttgggaatga aacaaaaatt
    19081 gggaattgct cttgccttac tgaaccatcc gtctatcgtt attttagatg agccgatgaa
    19141 cggtttggat ccacaagcaa caagagatgt gcgaaaaatc attaccgact tggctactca
    19201 gggcacctct ttcttgatct ccagtcactt actcagcgag cttgaaaaaa tggtcgatga
    19261 gctgatcctg atcaatcaag gaaagatcat caaacaatgt acaatggctg aattgaacca
    19321 aacagcgcaa gatttcatcg ttatctctac aacaaatgat ctagctgctc gaacgatctt
    19381 gacagaagct ggatatactt tggaagatcc tgataaaatc aagcttttaa aagaaaacga
    19441 agaattatta ggaaccgtga tccagctatt gtctgcacaa aatatccatg tgacagacgt
    19501 ccagcatctg acgaatgatt tggaatcttc tctattggaa attctggatt cagtaaaggg
    19561 ggaagaagaa aaatgacatt gcttgtaaaa caagaattat ttaaattgat caagaaaaag
    19621 tcaactgctg ttttatctgt tctattagtt gttttgctca taggaacagc acttctagcc
    19681 aaaaaataca cgacgatcat tgatccagtt gaaatgactg ctcagctttt tagtgccaca
    19741 tcttggattg tctttatcat gattgcagct gcaagcacga tcatttcgat ggaagcacaa
    19801 tatggtacat tgaaaaatct cctttatcga aagtattctc gaggagaaat attagtaagc
    19861 aaatggatca cattagttat ttattctgtt tatttatacc ttttagctat tattgtcact
    19921 gtgttgatga aactgattct tttcccttcg atttccttca cggagaaggt ttctactggt
    19981 caaacactga tccaaagctt gttcacttat actttgggta gttatatcgg tttatggctg
    20041 attttaagtt tagtgttgat gattgcttgc tttatcaata gttccggcgc atccatctca
    20101 gcaggaatcg tcttttattt tgcttcgtca atcatatctg gtatccttat tgcactcatc
    20161 caaaaatggg agtggatcaa atggaatccg atcagtatgt tgaatctgca aaaccaaatt
    20221 ggaaacgaag agatcatgaa gcaattgact catctttcta ctaatcaaat gctattcggt
    20281 aatttagctt acatcgtttt gttcttagca ttaggatatc tcgtatttaa gcgaaaaaat
    20341 gtatgatgac tcatcaaaaa agaggctgtg aaagagacgt tcagccttat tgccgattgg
    20401 ctgtctctta aacaccgttt attctgaaaa aggagctgtg acaacatttg tgtcacagct
    20461 cctttcctag tatgtttttg aataaacgac aggctcacaa cctctcttta tacttctttt
    20521 atacttctat acgtgaagca tcccagtggc aaataaaacc attgcaatca ctccgaccat
    20581 cgtcacacct ataagtaaaa tcttatctaa gtggatatgt tgtacaggct cgttttgctc
    20641 cttacgtgct ttgaggtaaa aataaatgcc tggcaagaaa agaacaagaa caagcattac
    20701 ttcattaaag gctacgacta gcatagccca tacttgaaag gcacttgcta aaagccctac
    20761 taaaaattgg acccattctt tccgctgata agaaagtttc atttggtaca atcctaagaa
    20821 aagccacgtg aagaaaatag ctgctgtacc aagtgtgtaa gcaaagttat aagcactgtc
    20881 agtgaataat aatgaaagta aaaagacatt cgtacataac gtcgtcaata cgatagcata
    20941 agttggtgcc ccatttttgt tgagttttcc ccatgcttta ggcaaaagtc cgtcttcagc
    21001 catgtttccc attgtttcaa tcggtaagat cgtccatgag agccaaacac caactaaaga
    21061 aatgatcaaa ccgccgttga tcacgactgc tccccattta ccaaccatca tttcaaacac
    21121 atagcccata gcaggctgcg ccttgatcgt ttgcagctga ttcatcgtca ttgtcccata
    21181 tggaagcatg gaaaccaaga cgtaaataat aatcaagccg aatatcccta gaatcgttgc
    21241 tttcccaaca tctgattgtt tttttgctcg tgaacctacg acagaggctc cttcaatacc
    21301 aacaaatacc caaagcatca ccatgatgca actcaatact tgactggaaa acgggatcgg
    21361 ctgtccattc gcattcaata taatgtcgct agaaaagtta tcaatgaatt gttggatcga
    21421 aaacgtgctg atagctacta caataaataa aaataatggc actaatttac agaatgtgac
    21481 gatagcattg acgaaactag cattttcgac tccccgattc actagccatg catatcccca
    21541 taaaaagact gtactcatca cgatcgatgc cagattttgc ccaccttcaa atactgggaa
    21601 gaaatatcct aatgcgctca tcaacaatgt tgcaaaagct acgttgccta accagcatgt
    21661 gagccagtaa ccccaaccgc tgataaaacc agcgaaacgg ccaaaacctt cttctgcgta
    21721 actaaagatc ccgcctttta aatctggacg ttttttattg atattattga tcgacaagga
    21781 gagcatcaac attgctgttc ctacgagtac ccaactgaaa atagctgggc cgccagccga
    21841 tccggagatg tccgtcataa taccaaatac gccacctcca atcgctgaac caattactaa
    21901 ggcagcaagt ggaattaaac caattccttt tttctgttgc tctgtatcca tgtaagcatc
    21961 ctccaaaata aaaccgcttt tatcaaaaag tataacaa
//
LOCUS       DAXLPC010000043        21967 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.043, whole genome shotgun sequence.
ACCESSION   DAXLPC010000043 DAXLPC010000000
VERSION     DAXLPC010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21967
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.043"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            4..816
                     /locus_tag="ACF3UE_001561"
     CDS             4..816
                     /locus_tag="ACF3UE_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFD3634970.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            813..1613
                     /locus_tag="ACF3UE_001562"
     CDS             813..1613
                     /locus_tag="ACF3UE_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFD3634971.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1774..3042
                     /gene="rseP"
                     /locus_tag="ACF3UE_001563"
     CDS             1774..3042
                     /gene="rseP"
                     /locus_tag="ACF3UE_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFD3634972.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3110..4819
                     /locus_tag="ACF3UE_001564"
     CDS             3110..4819
                     /locus_tag="ACF3UE_001564"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFD3634973.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            5031..9389
                     /locus_tag="ACF3UE_001565"
     CDS             5031..9389
                     /locus_tag="ACF3UE_001565"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFD3634974.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9534..10007
                     /gene="rimP"
                     /locus_tag="ACF3UE_001566"
     CDS             9534..10007
                     /gene="rimP"
                     /locus_tag="ACF3UE_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFD3634975.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10030..11205
                     /gene="nusA"
                     /locus_tag="ACF3UE_001567"
     CDS             10030..11205
                     /gene="nusA"
                     /locus_tag="ACF3UE_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFD3634976.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11227..11520
                     /locus_tag="ACF3UE_001568"
     CDS             11227..11520
                     /locus_tag="ACF3UE_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFD3634977.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11517..11828
                     /locus_tag="ACF3UE_001569"
     CDS             11517..11828
                     /locus_tag="ACF3UE_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFD3634978.1"
                     /translation="MNTVNRQEAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11841..14147
                     /gene="infB"
                     /locus_tag="ACF3UE_001570"
     CDS             11841..14147
                     /gene="infB"
                     /locus_tag="ACF3UE_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFD3634979.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNPNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14174..14521
                     /gene="rbfA"
                     /locus_tag="ACF3UE_001571"
     CDS             14174..14521
                     /gene="rbfA"
                     /locus_tag="ACF3UE_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFD3634980.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14678..15134)
                     /locus_tag="ACF3UE_001572"
                     /pseudo
     CDS             complement(14678..15134)
                     /locus_tag="ACF3UE_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            15299..17661
                     /locus_tag="ACF3UE_001573"
                     /pseudo
     CDS             15299..17661
                     /locus_tag="ACF3UE_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
     gene            18029..18952
                     /gene="truB"
                     /locus_tag="ACF3UE_001574"
     CDS             18029..18952
                     /gene="truB"
                     /locus_tag="ACF3UE_001574"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFD3634981.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            18956..19897
                     /gene="ribF"
                     /locus_tag="ACF3UE_001575"
     CDS             18956..19897
                     /gene="ribF"
                     /locus_tag="ACF3UE_001575"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFD3634982.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            20249..21034
                     /locus_tag="ACF3UE_001576"
     CDS             20249..21034
                     /locus_tag="ACF3UE_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3634983.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            21047..21898
                     /locus_tag="ACF3UE_001577"
     CDS             21047..21898
                     /locus_tag="ACF3UE_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFD3634984.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
BASE COUNT         7474 a         3844 c         4840 g         5809 t
ORIGIN      
        1 agaatgttac gtttttttcc gcaaaaaaac aaatatattc aagaaaaaag cgaatttcaa
       61 tttaataccg atggaccaat tcctcagcac attgccatca tcatggacgg caatggtcgt
      121 tgggcgcaaa accgtcgttt gccacgagtt gctggccata aagaaggcat ggaaacagta
      181 aagaaagtca caaaaaaagc atcaaggctt ggagtgaaag tgttgacgct ttatgccttt
      241 tcgactgaaa actggaagcg accaaaagat gaagtaagtt ttctcatgca actacctgtc
      301 gacttctttg atacgttcgt accagaattg attaaagaaa atgtcaaagt tcatgtcatg
      361 ggttatgaaa acgtattgcc agaacatacg caagatgctg taagacgtgc aattgagcaa
      421 acaaaaaaca atactggaat ggtattgaat tttgctttga attatggaag cagagcagag
      481 atcgtgactg ctgtccaaga aattgccgaa gaagtagcaa aaggagaaat acacgcagaa
      541 gaaatcgatg atgaattgat tgctaagcat ttaatgacag gtttcttgcc taaagagtta
      601 caagatcctg agctgatgat ccgtacaagt ggagaagagc gaattagtaa ttttctgtta
      661 tggcagatcg catatagtga gctgtatttt acaaaagcgc tttggcctga ttttgatggt
      721 gcgcatcttg aagaagcaat cgcctcttat caaaatcgag accgtcgatt cggcggtgta
      781 aaaaaaacag aagatgagaa aggggatcag tcatgaaaca acgtgtggtc acagcagccg
      841 tggcgctagt cttgtttatt ccgattatat ggatcggagg catagcggtt gagcttacag
      901 cagcaatctt agcagtaata ggagtttacg agctgtttcg gatgaaagga ttgacactct
      961 taagttttga aggagtttta tccgccgttg gtgcagtgtt acttgttttg ccaaaagaaa
     1021 gatggttttt ctttcttcca gagaatgtaa gtacatttat gttattttat cttatagtta
     1081 tgattctttt aggaacatca gttatttcta aaaatacgta tacgattgat gaagcaggtt
     1141 ttcctgtgct tgtcagcttg tatgtgggaa taggtttcca gaattttgtc aatgcacgaa
     1201 cagaaagctt ggctgttttg atatttggtc tatttattgt ttgggcaact gatatcggag
     1261 catatatggt tggtcgacgt tatggtcagc ataagttaag tcctgatatt tcgcccaaca
     1321 aaacgattga aggtgcgctc ggtggtattg gtagtgctgt tgtagtcgca tttctttatt
     1381 tattgctata cccagcaaaa gaactattta atcatggtat gtttgtcatg cttctgatga
     1441 cgattatttt ttcagcagtc ggacaatttg gtgatttggt cgaatctgca atcaaacgtc
     1501 attatgatgt gaaagactcg ggaaatatct taccaggcca tggtggaatc ttagaccgtt
     1561 tcgacagttt gctgtttgta tttcctatca tgcatttatt tggcattatt tagtaagtat
     1621 acctgcgttt ctttgtgaat ttcataaaag acgcaggttt ttatttttca ttatattgat
     1681 actattggtg tctttggtat actatggtaa aattatagtg ttttatcgtt gttttataaa
     1741 aaacacaaaa aacaagtaaa ggagaaaaaa gctatgaaaa cgattctgac atttatcatc
     1801 gtttttggta tattagtgat tgttcatgag tttggtcatt tcttctttgc gaaacgatca
     1861 ggaatcctcg ttcgcgaatt tgctatcggt atgggtccga aaatttatgg gcatcaagca
     1921 aaagacggga caacatatac gcttcgccta ttacctattg gcggttatgt tcgaatggca
     1981 ggcaatgggg atgatgaaac agaaatggca ccaggaatgc ctctttctct tttactaaat
     2041 tctgacggca tcgtagagaa gataaattta agtaagaaaa tccaattgac aaatgctatc
     2101 ccgatggaat tgagccgtta tgatttagaa gatgagctga ctatcactgg ttatgtgaat
     2161 ggagacgaaa cagaagtagt aacctaccct gttgatcatg atgcgacgat tattgaaaac
     2221 gacggaacag aaatcagaat tgcgccaaaa gacgtacagt tccaatcggc taaattgtgg
     2281 cagcgtatgc tgaccaactt tgctggaccc atgaataact ttattttggc aatcctgtta
     2341 ttcatcattc tggcatttat gcaaggtggt gttcaagtga cgaacactaa tcgcgtagga
     2401 gagatcatgc ctaatggagc tgcggcagaa gcaggcttaa aagaaaatga tgaggtagtc
     2461 agtgtggacg gaaaagaaat ccattcatgg aatgatctga caacagtcat tacgaaaaat
     2521 ccggataaaa cattagactt taagatcgaa cgagaaggtc aggtgcaatc tgtcgacgtg
     2581 acaccgaaat ctgtagagtc aaatggcgaa aaagttggcc aacttggtat aaaagcccca
     2641 atgaatacag gttttatgga taagatcatt ggagggacgc gtcaagcttt cagcggttca
     2701 ttggaaattt tcaaagcctt aggatcacta tttacaggtt tcagtttaga taaattaggc
     2761 ggacctgtca tgatgtacca attgtcttca gaagcagcaa atcaaggtgt aacaactgtt
     2821 attagtttga tggcgcttct ttcaatgaat ctcggaatcg tcaatctgct tccgattcct
     2881 gccttagatg gcgggaaatt agtcttgaat atttttgaag ggattcgcgg gaaaccatta
     2941 agtcaagaaa aagaaggaat attgacatta gctggctttg gatttttaat gttgttgatg
     3001 gtgctagtta catggaacga tattcaacga ttctttttct agaaaaagtt gacaaatagg
     3061 gtataataac aaacgataac tattttgagg aaataaagga gtatatagaa tgagacaatc
     3121 aaaaatgttg attccaacat tacgcgaagt tccaaatgat gcagaagtat taagccatca
     3181 aatcttgcta agagctggat atatccgcca agtatcagcg ggtatttatt catatctgcc
     3241 attagcaaat cgtgtattgg aaaaactgaa acgcattatg cgggaagaat ttgaaaaaat
     3301 cggagcggta gaaatgctga tgcctgccat cttgccagca gaactttggg aagaatccgg
     3361 gcgttacgaa acatatggac caaacttgta tcgtttcaaa gaccgcaatg atcgaaaaat
     3421 gatccttgga ccaactcacg aagaaacttt tactgatttg atgcgtaatg aaatcaattc
     3481 atataagaaa ttacctttaa atctttatca aatccaacct aaatatcgtg acgaaaaacg
     3541 acctcgcttc ggtttgcttc gcggaagaga gtttatcatg aaagatgcgt attctttcca
     3601 tgcaacggaa gaaagtttgg acgagacata taaagattac gaaaaagcct acaccgaagt
     3661 attcaagcgt tgtggcttag aatttcgctc gattatcgga gacggtggcg caatgggcgg
     3721 gaaagactca aaagaattca tggcgatctc agaaatcggg gaggatacga tctgttattc
     3781 gactgaaagt gattatgctg caaacttgga gatggctaca agctactatg tatcaaaaaa
     3841 atcgcatgaa acacagcttg aattggagaa agtagctaca cctaacgtaa aatcaattga
     3901 cgaagtagca gatttctttt ctgttgaacc tcaaaaaatc atcaagtctg tattgttcat
     3961 tgcggatgaa caacctgtcc ttgttttggt acgcggagac catgaagtca atgacgtaaa
     4021 actgaaaaac tttttatctg ctgacttttt agaagaagca acagaagaag aagcacaaaa
     4081 atatctaggt gctgagtttg gttctgtcgg accagtcggt gtttcagatg acgtaaaagt
     4141 atatgcagac cgttatgtcc aagatttagc gaatgccatt actggagcga acgaaacagg
     4201 attccactat aaaaatgtga atccagaacg cgatttcact gtactttctt atgaagatct
     4261 tcgttttgta caagaaggag atccttcacc agacaacaat ggtgttcttg cctttactcg
     4321 aggaatcgaa atcggacata tcttcaaaat cggcactcgt tacagtgaat ctatgggagc
     4381 aactgtacta gacgaaaatg gacgagaaaa atttgtgatt atgggctgtt atggtatcgg
     4441 tgtaagtcgt ttattatcag caatcgtaga acaacattca gatgaacaag gaatcaactg
     4501 gccaaaagga attgcgccat ttgatttgca tatcgtccaa atgaatctaa aagacgaata
     4561 ccaaacaaac ctgacgaatg aactagaaga agcgatgaca aaagctggct atgaagtact
     4621 ggttgatgac agaaatgaac gcgcaggagt gaaattcgcg gattctgatt tgattggctg
     4681 tccaatcaga atcactgtcg gtaaaaaagc agtggatgga atcgtagaag tgaaaatcaa
     4741 gaaaactggc gaaatggttg aagtacgtaa agaagaattg gtgaatactt taccaatcct
     4801 cttgaaccaa ggcgaataat aagcgttaaa acacagaaaa taaaaatagc tgaatcagct
     4861 gtttttgaca atctgatgat tcgcttttaa aattggaact gcgatttgaa tcgcagttcc
     4921 aattttttaa tgtaaaactc agaaaaaacg agtatactaa aaggtactga aaaagaagag
     4981 gataagatgc gatcaattgc attgtttctc atcagaaagg gcgtatatct ttgtcagaaa
     5041 aacgagattt atttgaaaaa ctgttggaac aaatccaact agaggaagca gaaaaaaatc
     5101 atccactgct tactgctggt gaaatggata gtgtagtggt ccatcgtaaa tcgcgtttat
     5161 gggaatttac gctgcatttt tccaaaattt tgcctattat gctatatcgg tcattgactc
     5221 agcatctgac tatcgctttt aaagatattg cacaagtcaa actgaatatc ttagcagatg
     5281 accagacatt cgatgaacag ctcttgcaag attactgggc ccaagctttg gaaaatcagc
     5341 aatgcgatac accactagca cagcaagtat tgaaaacgca ggtacctgtg ataaaagatc
     5401 gtaaagtcat cttgccaatc gacagtacag gagctatttc ttatttgaag caacaatact
     5461 tgccattagt agaagagttg ttcgtcagtt acggattccc aaaatttcgt atcgaaccag
     5521 aagtggatga gcagcaagcg gaacgagtat tgaaactttt tgaagaacgc aaacaagaac
     5581 aggcagaagc ctttatgaag caagcagctg aaagtctagt tgtccacgaa caaaagaaaa
     5641 aggaaagaaa agagcaatcg ccagctcttg aaggacccat ccacatccag ctaggacgaa
     5701 atattccagc cgatgaacca acgacaccaa tgatcagtat cgttgaagaa gaacgaagag
     5761 tcacacttga ggggtacgta ttcgacaaag aagtcagaga actacgttca aaacgcaaga
     5821 tcttgacttt gaaaatcaca gattatactt catcatttat cgtcaaaaaa ttctcgaacg
     5881 gcgaaaaaga tgaacaagta tttgatgcga tcagtgtcgg tagctggtta aaggtacgag
     5941 gaagtattca agaagatacg tttgtccgtg atttggtcat gaatgcgcaa gatatcatag
     6001 aagtcaaaca tacacctcgc aaagattatg ctcctgaagg ggaaaaacga gtagagcttc
     6061 atgttcatag caatatgagt acgatggatg caacaaacag catctctgat cttgtggcac
     6121 aagcagggaa atggggacac cgagctatcg ccattacaga ccacggtggt gcgcaagcct
     6181 ttccggaagc acatagtgct ggaaaaaaag caggtgtgaa aatcttatac ggcgtggaag
     6241 cgaatgtcgt agatgatggt gtcccaattg cttataatga tgcacatgaa gcattgagtg
     6301 aagccacata tgtcgtattt gacgtggaaa cgacaggatt gtctgcagta tatgacacga
     6361 tcatcgagct agccgcagtc aaaatgtata aaggaaatgt gatcgaaagc tttgatgaat
     6421 ttatcgatcc aggacatcct ttgtcacgaa caacggtaga tctgactggt atcacggatg
     6481 gaatggttcg aggatcaaag tcggaagaag aagtattgcg gatgttcctt gaattttcaa
     6541 aagatacaat tttggtagcc cacaacgcgg cttttgatat ggggttcttg aatactagct
     6601 acgcaaggta tggtattcct gaagcggcca atccagtcat tgatacgttg gaattagcta
     6661 gatatctgta tcctcaattc aaacgtttcg gattaggtgt gttatctaaa aaatttggtg
     6721 tcagcttgga acagcatcac cgagcaatct atgatgctga agcaactggt cacttagcat
     6781 ggatctttgt gaaagaggca atggacaatc ataacatgct ttatcatgat cagctaaatg
     6841 agcatatcgg agaaggagat tcttacaaaa gggctcgacc tttccatgta acgattttag
     6901 caaaaaatca ggcaggactg aaagatttgt tcaaactgat ttcaatgtcg aatgtcgaat
     6961 acttcgaacg cgtcccacga ataccacgct cccaattgaa aaagatgcgt gaaaatctat
     7021 tgatcggctc agcttgtgat aagggagaaa tattcgaagc catgatgcaa aaaggggtag
     7081 aagaggcaag aaaccgagca aaattctacg attatattga agttatgcca aaagcggtct
     7141 atgcgccttt gatcgagcaa gaattggtaa aaaatgaaca tgatttggaa gaaattatcc
     7201 aaaatttggt agaaatcgga aaaagtttgg ataaaatcgt tgttgcaaca ggtaatgtac
     7261 attatctgaa cgaagaagat gccatttacc gaaaaatttt gatcaattct atgggcggag
     7321 cgaatccgtt gaatcgtcat agtttgccgg atgtccattt ccgaacaacc gatgagatgc
     7381 taactgcatt tcacttttta ggggaagaaa cagcgaaaga gatcgtagta gaaaatacga
     7441 ataaaatcgc agatatctgc gaagaagtga ttccagtcaa agatgaactt tatacaccga
     7501 agattccagg ttcagaagat gaaatatcag aattgagtta cacaaaagca aaacaaatgt
     7561 acggagatcc gttacctgag atcattcaaa aacgattaaa aaaagagttg aattctatta
     7621 atggtaatgg cttctcggtt atttatctga tcgcccaaaa attagtgcat aaaagtaatg
     7681 aagatggcta tctagtaggt tcacgtggct ctgttggctc tagctttgtt gcgacgatga
     7741 caggaatcac tgaagttaat ccgttagccc ctcattatta ttgtccagag tgccaatatt
     7801 ccgagttttt tgaagatggt acgtatggtt ctggatttga catgccagaa aaacaatgtc
     7861 caaaatgtgg tgcacgctta aacaaagacg gtcatgatat tccatttgag acatttttag
     7921 gattccatgg agacaaagtg cccgatattg atttgaactt ctcaggtgat tatcaagcag
     7981 aagcccataa ctatacgaaa gtattgtttg gcgaagacta tgtttaccgt gccggaacga
     8041 ttggtacagt cgccgacaaa acagcatatg gctatgtaaa aggatacgaa agggacaata
     8101 atctgcagtt tcgaagtgca gaagtcgaca gattagcaaa aggcgctact ggagtcaaac
     8161 ggacaaccgg ccagcatcca ggggggatca tcgttattcc cgattatatg gatgtctatg
     8221 attttacgcc gatccaatat ccagcagacg atcaaaattc ggaatggaaa acgactcatt
     8281 ttgattttca ctcgattcac gataatgtat tgaaattaga tattctaggg catgatgacc
     8341 caactgttat tcggatgctt caagatttat cagggatcga tccacaaacg atccctacgg
     8401 atgacccgga agtgatgcgg atatttgccg gtcctgaagt acttggagta agtcaggaac
     8461 aaatttattc caaaacaggg acattaggta ttccagaatt cggcactcgt tttgttcgag
     8521 ggatgctaga agaaacgcat cctacaactt ttgcagaact actgcaaatt tccggactat
     8581 ctcatggtac agacgtatgg ttaggaaatg cggaagaatt gattcgacga ggagatgcga
     8641 cactggcgga agtaatcggc tgtcgtgatg atattatggt ttatttgatc catgctggat
     8701 tagatagcgg gatggcattt aaaatcatgg aaactgttcg taaaggacaa tggaacaaga
     8761 tccctgatga attgcgagaa acctatctat cggcgatgaa agaaaataat gtgcccgact
     8821 ggtatatcga ttcttgttca aaaatcaaat atatgtttcc gaaagcccat gctgcagctt
     8881 acgtattgat ggctcttcgt gtcgcttatt tcaaggttta tttccctatt ttgtattact
     8941 gtgcatactt ttctgtacgt gcagacgact ttgatctagt ctccatgtgc aaaggaaaag
     9001 atgctgtgaa acaagcaatg aaagaaatca cggacaaagg attagatgct tccgtaaaag
     9061 aaaagaatca actgacagtg ctggagttag ccaatgaaat gctggaacga ggattcaaat
     9121 ttggaatgat tgatttgtat aaatcggatg ccgttaactt tgttattgaa ggtgatacgt
     9181 tgatcgcacc atttagagct gtcccaagtt tgggaaccaa cgtggcaaaa caaatcgttg
     9241 aagcaagaaa agacggtcca tttttatcca aagaagatct tgccacccgc ggtaaagttt
     9301 caaaaacatt gatcgaatat atgaacgaca atggcgtatt gaaagatcta ccagatgaaa
     9361 atcaattatc gttattcgat atgctataag catctgtttt cctgtctgct tgtaatttta
     9421 agcagagtat ggtatagttc ttataggtaa tgatactaac tgtgagtgag cggatttttc
     9481 gctcactctt tttaatggaa ttacgcactt aattttttaa ggaggcgaaa cttttgagta
     9541 gcgtcgttga aacagtcaca gaaatggtga caccgatttt agatgaacaa aattttgaac
     9601 ttgtcgaagt cgaatttgta aaagaaggaa aaagctggtt cttacgagta tttattgaca
     9661 aagaaggcgg tatcgatatc gaagaatgcg cctttgtcag tgagaaactg agtgaaaaac
     9721 ttgatgcagc agatccagat ccgattcctc aagcctattt cctggaggta tcctccccgg
     9781 gagcagagcg gccattgaaa aaagaaagcg actatgaaaa ggcacttggt gattatgtcc
     9841 atgtctcctt ataccaacca gtagatggcg aaaaacaata tgaaggattt cttcaatcat
     9901 ttgatgctga acagcttaca ttgaaaatac gcataaaaac acgagaaaaa gaattgactt
     9961 ttgaccgaaa aaatattgca aaagctcgct tagctatcca attttaatca cggagaggaa
    10021 tcagaaaaaa tgagtaaaga aatgttaaat gcgttagacg ctttagaagc tgaaaaaggg
    10081 atctcaaaag aaatcgtgat cgatgcttta gaagcagcat tggtttctgc atacaaacgt
    10141 cactatggcc aagcacaaaa cgtcgaagtg gaatttgatc agaaaaaagg aaagatccat
    10201 gtctatgcgg taaaagaagt aacggaagaa gtgatggatt cacagttgga agtctcattg
    10261 aaagatgcac ttttaatcaa tccagcatat gagatcggtg atacgatccg ttttgaagta
    10321 acaccaaaag attttgggcg gatcgctgcg caaacggcta aacaagttat tttacagcgt
    10381 gtacgtgaag cagaaagaac gattatttat aacgaattca gtgcttatga aaaagacatc
    10441 atgcaaggaa tcgtcgaacg ccaggataaa cgttatattt atgtcaatct tggtaaaatt
    10501 gaggcagttc tttctaaaca agatcaaatg ccaaatgaat tttatcaacc acatgatcga
    10561 atcaaagttt atgtttcccg agtagaaaat acgtctaaag gtccgcaagt atttgttagc
    10621 cgcagccatc cagacctatt gcgccgctta tttgagcaag aagtaccaga agtctatgat
    10681 ggaatcgttg aaattgtcag catcgcccgt gaagctggcg atcgttcaaa agtggcagtt
    10741 cgctcaaatg atccaaatat cgatgcagtc ggtacatgtg tcgggccaaa gggacaacga
    10801 gttcaagcaa tcgtcaatga attaaaaggc gaaaacatgg atatcgtcga atggaatgaa
    10861 gatccagctg tattcattgc aaatgcattg aatcctgcac aagtcatgga tgtgatcttc
    10921 gatgagacaa atccaaaggc ctgcacagtt gtcgttccag actaccaatt atcgctagca
    10981 atcggtaaac gcggacaaaa cgcacgttta gctgctaaat tgactaacca taaaatcgat
    11041 atcaaatcag aatctgacat gacggaattt tatgaaaatc aagaacaaca aaaagaaaca
    11101 gaagaactgc atgatgaagc aatcgttcag tcagatttaa cagacgatga atatgaaaca
    11161 attgcattca acaatgaaac ggtcgaagaa aaaccagaag cttaacttta gtaaggaggc
    11221 aaagagatga aacaaaggaa aattccttta cgcaaatccg tggtttcagg tgaaatgaaa
    11281 cctaaaaaag agatggtccg aatcacccgt tcaaaagaag gggaagtatc gatcgatcca
    11341 actggaaaaa tgcctggacg aggagcgtat gtctcacttg agccggaaga agtacaacaa
    11401 gcttgggata aaaaaattct cgatcgagta ctcgaaacaa cattaacaga tgagttttat
    11461 caagaacttc ttgactatgt cactcaccaa aaagcacgta aagagttatt tggaaaatga
    11521 atacagttaa tcggcaagaa gccatgaatc tcatcggtct agcgatgcgc gcgggaaaac
    11581 taatcacggg tgaagaactg accattgctg aaatccgcaa acaaaaagca aaattggtgt
    11641 ttgtggcaac cgatgcaagc gagaatacaa gaaaaaagat aaaagataag agttcatatt
    11701 atgaagttcc ttgctttgag ctattttctg aagcagaaat cacgcagatg atcggaaaac
    11761 ctcgcaaggt attcggaata atggatgccg gatttgcgaa gaagaccaag gagctaattg
    11821 aaggttagga aggtgattgc atgggcaaca aaagaatcta tgaattagca aaagaactca
    11881 aaaaatctag taaagacgtc gtggaaaaag cacaacaact tggcatcgat gtgaaaaacc
    11941 atatgggtgc gattactagc aatgatgaga agaaattgca acaagcgttc aaaaacccaa
    12001 gcacgaaaca acaagctgca caacaagcaa gcagaaaacc agccaatcaa cagccgaacg
    12061 atcaacgtaa aaaagaaaca acgaacaatc aacaaaaaaa taaaaataac cgcagttatc
    12121 aagatcgcgg tcaagggagc ggtcaagtga atcaaggaaa aaaaccaaca acaaacccaa
    12181 ataatacggg aaataccagc agccaaaatc gtcaaggaac gagccaaggc ggcaatcaaa
    12241 accgtactaa caataacaac aaaccaaaca ataacaatcg cggcaaattt aataataata
    12301 accgtaatcg ttataataaa aaaggtaaaa aaggcaaaca gcaacaatca actaaaccag
    12361 ctgtaccacc acgcaaattc cgtgaattgc cagatgtatt agagtatact gaaggtatga
    12421 acgtagcaga tattgcgaaa aaaattcatc gtgagccagc agaaatcatt aaaaaattat
    12481 ttatgcttgg tgtcatggtc aatcaaaacc aagcactgga taaagatacg attgaactgt
    12541 tagcgacgga ctatggcatg gaaccacaag aaaaagtcca agttgacatt gctgatatcg
    12601 ataaattctt cgaggcagaa gaagtcgatc cagataaatt agtctcacgt ccgccagtcg
    12661 taacgattat gggacacgta gaccatggga aaacaacttt attggataca ttacgccatt
    12721 cacgtgtaac aagcggcgaa gccggcggaa tcacacagca tatcggtgcc taccagatcg
    12781 atattgatgg taaaccaatc actttcttgg atacaccagg acatgcggcc tttacaagta
    12841 tgcgtgcacg tggagcaagt atcacagata tcacgatctt agttgttgct gcagatgatg
    12901 gcgtcatgcc acaaacagtt gaagcaatca accatgccaa agctgcaggc gttccaatca
    12961 tcgtcgctgt aaataaaatt gataaaccag gtgcaaaccc tcaacatgtt atgcaagaat
    13021 taagtgagta tgagttaatt cctgaagcat ggggtggaga aacgatcttt gttgagatct
    13081 cagcgaaatt cggccaaaac atcgaagaat tgctggaaat gatcctgtta gtcgcagaag
    13141 tagaagattt aaaagcagat ccaacacaac gcgcaatcgg aacagtgatc gaagcacgtc
    13201 ttgataaagg taaaggtcct gtgtcaacct tacttgtcca agaaggaaca cttcatgttg
    13261 gtgacccaat cgttgtcggt aatacttacg gacgtgtccg tgtaatgaca aacgatcttg
    13321 gccgtcgcga taaagaagca ggacctgcaa cgccagtaga aatcactggc ttgaatgatg
    13381 tacctcaagc aggtgaccgt ttcgtagtct tcgaagacga aaagacagca cgtgcagcgg
    13441 gtgaagaacg cgcgaaacgt gcattattag aaaaccgtgc tgccacaagc cgtgtgactt
    13501 tggataactt atttgaaagc ctgaaagaag gcgaattgaa agaagttaac gtaatcatca
    13561 aagcagatgt acaaggttca gcagaagcac tggctgcatc attgaagaag attgatgtgg
    13621 aaggtgtccg tgtaaaaatc gtccattcag ctgtcggagc aatcaatgaa agtgatgtaa
    13681 ccttagcagc agccagcaac gctattatca tcggtttcaa cgttcgtcct acaccgcagg
    13741 caaaagtgca agctgatact gaagaagtcg atattcgtct tcaccgtatc atctataaag
    13801 ccatcgaaga aatcgaaact gcgatgaaag ggatgctaga ccctgaattt gaagaaaaaa
    13861 tcaccggtca aatgatcgtt cgtgaaacct tcaaagtttc taaagttggt acgattgcag
    13921 gtgcctatgt aacagaagga tatattcgta gagatagcgg tgtccgtgta atccgtgacg
    13981 gaatcgtaat ctatgaaggc caacttgcaa gtctgaaacg attcaaagat gacgtgaaag
    14041 aagtcaaaat gggttatgaa tgtggtgcaa tgattgaaaa attcaatgac atcaaagtag
    14101 atgacgtaat tgaaggattt atcatggaag aagtcaaaaa tgactaaaaa ctgataaaag
    14161 gaggccaatc attatggcta actaccgtga ccgccgagtc ggtcaagaaa tcttaaaaga
    14221 agtcaatgat attttgcgca aaaaggtccg tgaccctcgt gtggagaacg taacgatcac
    14281 agatgtgaaa gttacggggg acttacagca agcaacgatc tattacagca ttttatctga
    14341 cttagcatca gataagaaaa cagcacaaga tggattgaat aaagcatcag gattgattcg
    14401 tcgagagtta gggcacaatc taagtattta taagacacct gaattgttct ttgaacttga
    14461 tgaatcagtt gtctatggca accatatcga tgaattgctt cgcgacttga acaaagacta
    14521 atcaaaaact cccgcaaatc ctgtgaaatc aggggttgcg ggattttttt gttttcatta
    14581 agacgtatta cctaagagtt ccatgacttt agtcttgcgg cgtgtcagct aaccaaaaaa
    14641 gagaaaaaga aaagtaaaaa attcgacttt cttttttcta gtagtatata aatttttgca
    14701 tatagataaa gatcaagata ccgataacgg aagctagatt gtaatctatt ttagtgacag
    14761 tcaggtatag ccaagtaact agaagatcag tggaacctgc accataaaag tttgagtttg
    14821 tcggtccgtt gacagttaaa agaaaaatca cgttgaagtt attgatattt ccgattacgc
    14881 cgcttcgatt tggtcacgat ccaaattttg gataatccct gtagaaatta gcatagtagc
    14941 tgggatacca attcacatat tgacaaagat aacagagact tttacataaa acggatcaat
    15001 caggaaagga attgctcgat ccagccccag ttttccagca atgtgttaac tggcccagcg
    15061 tcattcagca aattatgcat gatgaggagc gaaatgaact gcggaacagc cattgtgata
    15121 acgacaagtt ttttggatca atgtaaaaaa cgtcagcgaa aggaaaaatt tcgtggtttt
    15181 ttatacctgt tcatttggct agatataaaa tccaaacaaa tgaacagaag tgcttattag
    15241 gtttcaattg ggagtatctg cgctagaata agagtaataa tgaaaaggag tgttatgtat
    15301 ggattattct agtaaagaat actttgataa aatgacggct tggtggcgtg ctgctaatta
    15361 tctttctgtt gggcaacttt atcttaaaga taacccctta ctgagacgta cactgaaacc
    15421 cgaagatgtc aaaaaacatc caatcggtca ttggggaacg attcctggcc aaaattttat
    15481 ttatgtccat ttgaaccgag tcatcaataa atatgatttg aacatgtttt atattgaagg
    15541 gccaggacac ggcggacaag tcatggtatc gaatgcttat ttagatggaa gttacacaga
    15601 gatctatcca gaagtaacgg aagatgagac aggaatgcaa aaattattca aacgattttc
    15661 atttcctgga ggcattgctt ctcatgcagc accagaaaca ccaggttcta tccatgaagg
    15721 cggagagctt ggatactctc tttcacatgc agtcggagct gtattagaca atcctgaagt
    15781 aatctctgct gtcgtgattg gtgatggtga agcggaaacc ggtcctttag ctggaagctg
    15841 gttctcaaat gtctttatca atccagtgat agatggagct gttttaccga tccttcattt
    15901 aaatggtgca aaaatagcca acccaacgat cttggcacgt aaatcagatg gagaattagc
    15961 aaattacttt aacggacttg gctgggaacc tttctttatt gaaggaaatg attcagaaaa
    16021 attaaatcct gttatggctg aaaaaatgga tcaagcaatc gagaaaatta aatccatcca
    16081 aaaagaagct cgcctgaaga cagcaacaga tgtcgtgatg ccaaaatggc cagtattgat
    16141 cgtacgcaca ccaaaaggat ggaccggtcc aaaagaatgg gacggggaac caattgaagg
    16201 aaccttccga gcacaccaag taccgattcc tgtagatcaa gaacatatgg atcatgcaga
    16261 tgctttactc cgttggctga aatcctatga accagaaaaa ttatttgatg cacaaggacg
    16321 tattttagaa gaaatcagag aaatcgcgcc tactggtgac caaagaatgg caaaaaatcc
    16381 tatcaccaat ggtggaatcg atccaagacc gcttattatg ccagattgga aaaaatatac
    16441 tttgcaattt gaaaaaccag gctccgttaa agcagaagat atgaccgaac ttggtaaatt
    16501 cgttcgcgag atcattgaga aaaatccaga aaatttccgt atatttggac cagatgaaac
    16561 aaaatcaaac cgattgaatc aagttttcaa aacgacaaat cgccaatgga tggaaaaaat
    16621 cgaaccagaa aatgatgaat ggctttcgcc atctggtcgc gtcatcgaca gtcaattatc
    16681 ggaacaccaa gatgaagggt tcttagaagg gtacgttctg actggacggc atggtttttt
    16741 gcaagttacg aatcattctt gcgagtggtt gactctatgt tgactcagca cttcaaatgg
    16801 atgcggaaat cacatgacct ttcttggcga aatgattatc cttcgctaaa tctcattgca
    16861 agctcaacag tcttccagca agatcacaat ggatatagcc accaagatcc aggaatattg
    16921 acacatttgg cagaaaagaa ggcggagttc atccgtgaat atctgcctgc ggatgcaaat
    16981 acattgctcg cagtcatgga taaagcattc cgctcgtcag aaaaaatcaa tttgatcatc
    17041 tcttccaaac atccgcgtgc tcaattttac tcagcagaag aagcagccgt cttagtgaat
    17101 gaaggcttga aaatcattga ttgggcttcg acagcaaaag aggaggaacc tgaattggtc
    17161 attgctgctg caggaacgga atctaactta gaagcattag cagctgtaac tttgctgctg
    17221 gaagaattcc caaaactaaa aattcggttc atcaatgtcg tagatttatt gaaattacgt
    17281 catccaagtc aagatccgcg tgggttgagc gatgaagaat ttgatcaata ttttacaaaa
    17341 gacaaaccga tcttatttgc tttccacggt tatgaaacat tggtccgcac gattttcttt
    17401 gatcgtcata accatcattt aatgattcat ggctacaaag aaaatggaga tatcacgaca
    17461 ccatttgaca tgcgtgtagt aaatgaactt gatcgttatc atttggcaaa agacgcagct
    17521 ttaaaaatca aaggaagtca agcagaagat tttgcgaaaa aaatggatca gaaattacaa
    17581 gaacatcaaa actatattcg tgaaaatggt attgatctgc cagaagtatt ggattggaaa
    17641 tggaaaaatc ttgaccaata aaatgataaa atcgatcccg caaaatagaa ttttttacat
    17701 tgattaagaa actgaaaaaa taaataaaaa aaacggaaaa aagactggaa gaatggccag
    17761 tctttttttt cgtttttggg aagtgaaaac caaactattt acctgtaagc cacccataaa
    17821 tccaatcaaa tggtgcaaag aaaaaatctt ccattctatt ccctccttta aaaaagcata
    17881 acatgatttc tatttacgtg agcatgaatt ttgttacgtt tttattgccg aaaaataaaa
    17941 accgttcatt atgatgtcaa attcgtcagt aattgatgca atgtgttata ataattcagt
    18001 taaatcaaaa atgaaatgga gaaaagacat ggacgggtta ttacctttat ggaaagaacg
    18061 cggaatgaca agtcatgatt gcgtattcaa attaagaaaa atcttacata cgaaaaaaat
    18121 cggacatggg ggtacgcttg acccagacgt agacggtgtg ttgcccattt gtattggaaa
    18181 agccacaaaa gttatcgaat atttgacaga ttctgggaaa atctatgtag gcgagataac
    18241 tctaggtttc agtacaacga cggaagatcg atccggagaa cgggtagaaa caaaaccagt
    18301 agatatgtct ttatctgaaa aaaaaataga tgaagtgatg gcttcattta ttggtgagat
    18361 cacccagata ccaccaatgt actcagcggt aaaagtcaac ggtaagcggt tatatgaata
    18421 tgcccgcaat aatgaaacag tggagcgtcc tgttagaaag gctcagattt accgttttat
    18481 ccggacaagt gaattgacaa gagacgaagt gacaggaacc atttcttggc gcttcgaagt
    18541 agaatgcggg aaaggaacct atgtccgcac attagctgta gatacaggca agaaacttgg
    18601 ttaccctgcg cacatgtctg atctgacccg aacagcaagt gccggtatgt cccagaagga
    18661 tgctctgaca ttagaagaag tagctcaagc tgtgaaaaat gggacaatcg atgattgttt
    18721 gctgccaata gaaaaaggag tggaacggtt caaacgagta gatattactg atgaagtatg
    18781 gcagaaagta aaaaacggta tgagacttga ttatactgta tttgcgctcc cagaaatgcc
    18841 gtcagaagaa attgctttgt tttataaagg aaaagttgtc agtatttatc agccaaaccc
    18901 gaaagaaaaa aacaaattaa aacctagtaa agtattgaga aatgaggaat aacgaatgaa
    18961 tatcatcaag atcagacatc cttaccaatc agaacaaatt ccagaagacg atgtcgtttt
    19021 agtgctggga tttttcgacg gcgtgcatat cggacaccag aaagtcataa agacaggtat
    19081 ggaaattgca caaaaagaag gattgaaatt agcattgatg actttcaatc agcatccatc
    19141 tattgtcttt aaaaagatcg atcctagcag cgtgaaatat ttgactagcc ttaagcaaaa
    19201 agaagaaaaa atggccgctt tgggtataga ttatttatat gaagttgatt ttacttcttc
    19261 ttttgctcat ttagcaccgc aggaatttgt tgatcaatac atcgtagggt tacatgcaaa
    19321 atatgctgtt tccggttttg attatacgta tggaccaaaa gacattgcag atgtcgctca
    19381 ttttcctgaa tatgccaaag gaagattcaa aatcgtcaca gtttctaaag aagaagaaca
    19441 aggtgaaaaa atcagctcta cccgtattcg tggattacta gacagcggac aagtaaaaga
    19501 agcagcaaaa ctattaggtt gcacatatga ggtagaaggg gtagttgtcc atggcgatgc
    19561 acgaggcaga ctactaggat tccctacagc aaatgtcaaa gtaaagagca cggttcattt
    19621 gcctaaagaa ggtgtttatg tgtcggaaat aaaaattggg gaaacatggt atccagccat
    19681 gggttcaatt ggacataatg atacattcgg tgaaggacgg gagctgactg tagagttgta
    19741 tattttggac tttaatcaag atatctatgg tgaacatgtc gcggtacgct ggaatcaatt
    19801 tttaagagat caagtgaaat tttctagtgt agaggaattg attgaacaac tcaaggagga
    19861 tgaacaagca acagctgaat atttttctca gcaataaaac attatgcata aaatctcttg
    19921 tttatgtata actagcaatt acaataaaat gggtgataaa taagcccagg aaaggggctg
    19981 tgacaaaagt cttgtcacag cctttttttc caaataaatg gtttttcaga agtagcttct
    20041 tcggaaataa gccgaaattt cttgaagctg accacttctg tcacaacctc tttctttata
    20101 gaaataaaag gacactagca attcatgaaa acgattgcta gagcgtatca tttgctttag
    20161 actatatatc ttggtgtaca ctcactttaa ggcggaaata aaagttatcc gtaataacag
    20221 gtttaggtat gaaaaaggag tgggtactat gtacaaggaa ttagaaaaca aagtcgcagt
    20281 agtaactggt ggctcaaagg ggattggaac agcgattgct caacgattcg ggaaagaaaa
    20341 aatgaatgta gttgtcaact ataactcgga taaagaagga gcagaaaaag cagtcaaagc
    20401 aatcgaagag gcaggcggaa aagcagtctc tgtacaagca gatgtcagtt ctgaagaagg
    20461 aatacagcgt ttacttgata cggctttaga aaattttggg acactggacg tttgggttaa
    20521 taatgctggg atggaaaatc agcatccaac ccatgaactt agccttgaag attgggaaag
    20581 agtgttaaaa gtcaatttga ctggcgtttt tatcggaacg aaagcggctt taaattactt
    20641 tacagagaat aataaaaaag gaaatatcat caatatgtct tctgttcatg aacagatccc
    20701 atggccaacg tttgctcatt acgctgcttc aaaaggcggg gtaaaattat ttaccgaaac
    20761 ggtagcaatg gagtatgcac cgaagggaat cagaatcaat agtataggcc ctggtgctat
    20821 ccgtacacct attaatgcgg caaaatttga tgatcctgaa caaaaagaac tcttggaaag
    20881 tatgatccca ctaggacgcg taggtgaacc aaaagaaata gcggcgacag ctgcatggtt
    20941 ggcttcagac gaatccagtt atgttacagg tattacacta tttgcagatg gtgggatgac
    21001 tttatatcct tctttccaag gtggaaaagg ataagggtga ataaaaatgg gtttattgat
    21061 tgcattgatc ccggcagttg gctgggggat ccagccactg attttgaaaa agattggtgg
    21121 cagaccaaca aatgagatat taggaactgg tattggagcg gtgcttgtcg gcttactcgt
    21181 tcaattattc gcttctccag ctggtatttc agtgactaca tttttgatta gtttactttc
    21241 tggtgcattt tgggttattg gacaaacagg acagtataca tctttcaact tgattggtgt
    21301 ttctaaaacg atgccaattt cgactgcatt acagttagtc ggaacctcgt tgattggtgt
    21361 cttcgctttt ggagaatggt ctggaagtat ggggaaaatc attggagcag cagcaatcat
    21421 tcttcttgta tttggttctg ctttaacggc aatcagtgat gatcctggaa aaaaaggcgg
    21481 tatcacaaaa ggaattagtc tattagcatc aacaagtatt ggttattggg tatacagtgc
    21541 attgcctaaa ctagttgatg caagcggact ttccattttc tttccgcaaa tgatcggtgt
    21601 ctttttaggg gcagtgattt atgtgatttt ccgtaaacca accgcatttt ctgaagacaa
    21661 gagttggaaa gcaacgatcg ttggagccat ctttagtgtg tcagcattgg cttatatttt
    21721 ttcagcaaat gaaaatgggg ttgctactgc atatatcatt acacagctaa acgtagttat
    21781 ctctacatta ggcggtatgt acatcctgca tgaaaataag acaccaaaag aaaaaaaatt
    21841 aacgattatc ggattattgc tgatcgtagt aggaagcatg gtcacggtct ttatttgagg
    21901 ataaagatgg taaaatttca tttattaaaa aaatatttgt ttgaaccaaa cagtaagtac
    21961 ttataaa
//
LOCUS       DAXLPC010000044        21886 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.044, whole genome shotgun sequence.
ACCESSION   DAXLPC010000044 DAXLPC010000000
VERSION     DAXLPC010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.044"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(117..635)
                     /locus_tag="ACF3UE_001578"
     CDS             complement(117..635)
                     /locus_tag="ACF3UE_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFD3634985.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(637..1254)
                     /locus_tag="ACF3UE_001579"
     CDS             complement(637..1254)
                     /locus_tag="ACF3UE_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFD3634986.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(1251..2105)
                     /locus_tag="ACF3UE_001580"
     CDS             complement(1251..2105)
                     /locus_tag="ACF3UE_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3634987.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(2102..3013)
                     /locus_tag="ACF3UE_001581"
     CDS             complement(2102..3013)
                     /locus_tag="ACF3UE_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3634988.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(3054..4388)
                     /locus_tag="ACF3UE_001582"
     CDS             complement(3054..4388)
                     /locus_tag="ACF3UE_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3634989.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            4596..5426
                     /locus_tag="ACF3UE_001583"
     CDS             4596..5426
                     /locus_tag="ACF3UE_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFD3634990.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(5670..5919)
                     /locus_tag="ACF3UE_001584"
                     /pseudo
     CDS             complement(5670..5919)
                     /locus_tag="ACF3UE_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6110..6304)
                     /locus_tag="ACF3UE_001585"
     CDS             complement(6110..6304)
                     /locus_tag="ACF3UE_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634991.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(6809..6994)
                     /locus_tag="ACF3UE_001586"
     CDS             complement(6809..6994)
                     /locus_tag="ACF3UE_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634992.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(7844..8185)
                     /locus_tag="ACF3UE_001587"
     CDS             complement(7844..8185)
                     /locus_tag="ACF3UE_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFD3634993.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVIRPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(8185..8415)
                     /locus_tag="ACF3UE_001588"
     CDS             complement(8185..8415)
                     /locus_tag="ACF3UE_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFD3634994.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            8711..9049
                     /locus_tag="ACF3UE_001589"
     CDS             8711..9049
                     /locus_tag="ACF3UE_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3634995.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPIQIET
                     LVQRISTREDFAIVECEIVAIFVEEGILHDPTHINVDKWQPLIYKLREYTTANQSLSL
                     NFRFQEFKES"
     gene            complement(9254..9829)
                     /locus_tag="ACF3UE_001590"
     CDS             complement(9254..9829)
                     /locus_tag="ACF3UE_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006974 - DNA damage response [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HFD3634996.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPEQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGF
                     YEWNEEKDKFMFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRMPLVL
                     TEEQIEPWVTDVSFARKIITQQMPELVMEKV"
     gene            complement(10194..10775)
                     /locus_tag="ACF3UE_001591"
     CDS             complement(10194..10775)
                     /locus_tag="ACF3UE_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3634997.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASETGKGQFYYYFS
                     SKKEVCLAVIHAHMVVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWIKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(10958..11584)
                     /locus_tag="ACF3UE_001592"
     CDS             complement(10958..11584)
                     /locus_tag="ACF3UE_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFD3634998.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFSLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(11606..12934)
                     /locus_tag="ACF3UE_001593"
     CDS             complement(11606..12934)
                     /locus_tag="ACF3UE_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFD3634999.1"
                     /translation="MEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTCI
                     NIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARFL
                     SNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPEK
                     LVIIGAGYIGLEFASMFNEYGSKVVVLDAHPEFLPREDEDIAQMILEDMTNAGIEFHL
                     GVSVDQVADQESTAAVTFTENGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDRG
                     AIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVPY
                     SVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETDL
                     ILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(13093..13494)
                     /locus_tag="ACF3UE_001594"
     CDS             complement(13093..13494)
                     /locus_tag="ACF3UE_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFD3635000.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(13580..13786)
                     /locus_tag="ACF3UE_001595"
     CDS             complement(13580..13786)
                     /locus_tag="ACF3UE_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635001.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(13881..15383)
                     /locus_tag="ACF3UE_001596"
     CDS             complement(13881..15383)
                     /locus_tag="ACF3UE_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFD3635002.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(15401..15856)
                     /gene="argR"
                     /locus_tag="ACF3UE_001597"
     CDS             complement(15401..15856)
                     /gene="argR"
                     /locus_tag="ACF3UE_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFD3635003.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(15954..16571)
                     /locus_tag="ACF3UE_001598"
     CDS             complement(15954..16571)
                     /locus_tag="ACF3UE_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFD3635004.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            16792..18165
                     /locus_tag="ACF3UE_001599"
     CDS             16792..18165
                     /locus_tag="ACF3UE_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3635005.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            18240..19352
                     /locus_tag="ACF3UE_001600"
     CDS             18240..19352
                     /locus_tag="ACF3UE_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3635006.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(19424..21061)
                     /locus_tag="ACF3UE_001601"
     CDS             complement(19424..21061)
                     /locus_tag="ACF3UE_001601"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFD3635007.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(21229..21837)
                     /locus_tag="ACF3UE_001602"
     CDS             complement(21229..21837)
                     /locus_tag="ACF3UE_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3635008.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         6383 a         4453 c         3821 g         7229 t
ORIGIN      
        1 atttaacaaa acttaagtta ttaagacaaa tgaataaaca actacgcttt cctcgaaaca
       61 aaaaaataaa gcacaaatgc gcatttacgc actcatgctt tattcgtaca attaattcag
      121 ataacggcag cgcataggat gccaataaca cttcctaaaa tagctcctcc taaaatgtca
      181 gtaggataat gtaaaagtaa aaaaatcctc gaataagcga tcaaacaagc aaataaaaag
      241 gctaatattc ctgcaactgg acttaattcg aacaacgcag ctactgataa aaaggctagc
      301 gctgtatgtc ctgaaggaaa agaagaagtc ttcggtttac ttgtgtaaag gacaagccga
      361 cgattttttt cataaggtct tttccgtctt gtcgtttttt tgataaaaag caaaccaaca
      421 aaaaaataga tcaaactgcc gataagaatg gctagaccat attctctagt atcaggtatc
      481 aagactaaaa cagcagcaag gagcaaccaa ataaaaccac cattagagat attactgata
      541 aatttcaaaa aattgatttt tcgactatcc gttttccgtt gcttggcgaa cttgttgata
      601 atactatcat cgattttagc aatcaaacgc aacatgttat tcctcctttt taagaacctt
      661 ttcttgcgta cgatggataa aaagcaggac ttgaaaataa aacaagaaac tgaaacctaa
      721 taaagcaaaa tagattggtc ctgcaaacca gaatgcgaca agaaggatca acgtgcctgc
      781 caaatagaaa agcgcgcttt tgaaatcatt aaaaaacaag aaaaatgcag taatccaaga
      841 agcttctttt tgttccagtt gaagcaagat tttgtaacta aagagaagcg cgcttaatag
      901 aagcaaaaac aacgtagtat acatcaatgt atagccaatt cccccacccc aatagcggaa
      961 aatctgataa tcgatcaata gaagaagaaa ataaacactt gctaaactat cttgctttcc
     1021 ataaagagag aagttctcac gaaacttttt ccagaatagt gaaccgagct ttttctcttc
     1081 attttttttg taatgataaa tcatatacag aactgttcga cttgcagttc ctaatgtgaa
     1141 aacaggcaag acgcacagga accatagtag ctgtaaatgg ataagacgtg gaatccattc
     1201 aatgatttct aagaaataat cattggcttt tttaccaatc gatcgattca tcatcctttt
     1261 gaacctcctg tcaaatccat cccttcaatg aaataacgtt gtgcaaaaaa gaacagcaaa
     1321 atcgtcggga tcaagacaag tgttgctcct gccatcagat aattccattg tgtcgttgct
     1381 tggttctgaa aaacttgcaa gccaatctgt aacgtgtatt tttcttgatc ttggatatat
     1441 aacagaggac ctaagaaatc attccaagct gcgttgaagg aattgatcgc aatggtaatc
     1501 aaggcaggtt tcgtcaatgg aagcatcaaa tgactccaaa tatacaaatg attcgctccg
     1561 tcgatttcag cagcttcgat caattcatta ttgatcgata agtaaaattg acgcatcaga
     1621 aatatattga acgcattgcc gaagaacgat ggaacgatca ggggcaaata agtacctacc
     1681 cagccgatct tggagaataa tacatattga gggatcatcg ttacaaaccc cgggatcatc
     1741 atcgtagaaa gaaccaaagc aaacatcagc tttttcccag gaaaatcaag cttcgcaaat
     1801 ccataagcaa taaaagaatt tgaaaggaca ttaccgatca ctactagcac agtgatgaat
     1861 aatgtatttc ttgcatagcg ccaaaaagga aaggcggcaa tcgtatccag atagttttcc
     1921 catacgattt tttctgggaa aaaggtcgga ggataacgaa cgatttcttc cattggtttc
     1981 aatgaagtaa acaccatcca aagcaatgga atgatcaaaa tgattcctat tactgtcatg
     2041 aggacataac ttagtatttt ttttgtttgc cgattcacac tggtcttttt gaaataatcc
     2101 atcatttgcc gtcacctcca gaataataga cccacttagg tgcaagcttc aaattgacaa
     2161 acgtcagaac caacacgatc agaaacagga tcattgacat agccatcgca taacccatat
     2221 caaaagctac gaacgccttg ttccacatat gcagattata aaaaagcaaa gaatttgcag
     2281 gtccgcctgt tccatttttc gtcatgacat aagcttcttg aaaaatttgg aaagaaccga
     2341 tcgtagaggt gatcacatcg taaaaaataa taggagtgat taatggcaaa gtaatacttt
     2401 tgaactttcc ccaaacgcct gctccatcga tttctgctga ttcatataaa gatctaggaa
     2461 cattttgtaa tgtagctaag taaagtagca ttgctcctcc agaactccat attttcatca
     2521 aaatcaacgc aggtttcgtc cattgtggat caaacagcca agctggtcca gggatatgga
     2581 accagcccag aaatgtgttg atcaatcctg cagatggaga aagcagctgc atccataaga
     2641 tgtagactgc tactcctgat aagactgccg gtaaatagaa agctgtacgg aatacactga
     2701 ttcctttgat tttttgattg agtactgtgg ctaaaaacac actgaaaatc gtcgtcagcg
     2761 gtacattgaa gatgacgaaa taaacggtgt tgtataacga tttccaaaat aaatcatcgt
     2821 gaacgaacat tcttttgaaa tttgctagac caatgaaatt catcttggat gtcaaattat
     2881 aatcggtgaa actaccaata actgaaaaaa gcataggccc tagcataaat accaagaacc
     2941 cgataataaa aggcgagata aataaatagg cccatcttgc ttcttttttc tttcggatag
     3001 ataaacgctt caaattttct tgcctcctct gtacctagac agtcaaaaat ggattattga
     3061 ttttgcttga ctaagttttc tactgctttt tgtgcatctg ccaatccttc ttttggtgat
     3121 tttgttccta aaagaatctg gtcaatctgt tcattcacta atgtcgtgta atccggagca
     3181 tctaaaggaa ctggtgtgat caccgtattt ttaaagtttt cgtccgccat ttgatagatc
     3241 atttttcctt tatccgttag gttgtcatta ttcactaaat tctcattggc tgtcttgctc
     3301 gccatgatat caaaactttt ttcgccgaat ttttcttgta cttctggaga agaaagatat
     3361 ttgatgaatt cataagaggc ctcaggatct tttgctccgt atggtacttc caagacgaat
     3421 ccgccacccc acgaccaatg gcctgaacct tcttcttttt ctgggagctg catcacgcca
     3481 aaatcaaaat catccggtgc attttccatc aaactagagt aataattgat attttgggca
     3541 cgcatggcta ctaatccgga aataaatgga tcagatacac cagacccaaa ttcggcttct
     3601 aatttattga tcgtattttt cccataataa tcttgccagt cttggatcca ctccaaggct
     3661 tccactttat ttttagtatc aatcttgact ttttcatctt tgtcaaacca actagtcccg
     3721 ttatctgcgt ttagcgccca tacatcagcc cctaaattcc ataatggata aaaaccgatg
     3781 cgtgtaaatt cttttccttc ttttttatct agtttacgtg ctgtttcttc taattcatcc
     3841 caagttgtcg gtagatcttg ttcactgatt ccagcttctt taaataactt tttattataa
     3901 aaaatgactt gtgtatctgt attgaatggg atcgcataag gatcaccttc atattctact
     3961 gtatcccaaa gctgcggata aaaatcctta gaagtgtctt tttctacata tttggagaga
     4021 ttagttgctt gctgtgcttc tgctctttgg gcaacggaat ttatgtcctg tacaataaca
     4081 tcgggtgcat ttccagctgt tattgcagat aaagatttag tccagatgtc accccatggc
     4141 tgatacttat aatttacatg gatctcgttt tgtgattgat tgaaatcctc aatgatttct
     4201 tcgatagctt cttttcgtgc accggatccc caaaaggacc agaaatcaat attttttctt
     4261 ccatcacttg ttttttcaga agaatttgct gcacttgaac tggcatcgct tgcattactt
     4321 gatccgcatc ctcctaataa aaacaatgct gaacttgcca gcaaccctgt aaacaataat
     4381 tttttcatat tttacctcca aattttaatg taaccgatgc cggttttaat ataacgatat
     4441 cattttgttc tgaaaataac aatttataag gtatgattct aaaaaaatta ttaatgatac
     4501 caatacttta tataattcgc gagcgctttc tttgaatttt ttaatctttc gtagcagaat
     4561 gagaatgtat taaaaataga ttaggaggaa ttttgatgtt tagacaccag aaagaattgc
     4621 agtttgaagc aaaaccagat cgtccgaatc cattaatcgc gaaatatctg caggagctga
     4681 tcggcggcca atatggcgag atgagtgtag ctatgcagta cctgttccaa ggctggagct
     4741 gccgaggaga agaaaaatat aaagatatgc tgatggacat tgcaacagaa gaaatcggcc
     4801 acgtggaaat gttggcgaca atggttgctc gtttattaga gggtgcgcct gttgaagatc
     4861 aagaagcagc gatgcaaaaa gatccaacaa tcggtgccat tatctctgga atgaatccac
     4921 agcacgcgat cgtagctggc ttaggacctc gtcctgctga cagcgtgggc aatccatgga
     4981 gcggtgccta tatcattgcg agtggcaact tgttagcaga ctttagagct aatttaaatg
     5041 ccgaatcaca aggaagactt caagtagcac gtatttacga aatgatcgat gatcgtggcg
     5101 taaaagatat gctgtctgtt ctccttgcaa gagatagcta tcatcaaaat ctatgggaat
     5161 gtgcagtgaa agaattagaa gaaaaagaag gttcaatctt agtcccaagt actttcccgc
     5221 gtgacaaaga acgaaaagac attgcttatg acttctataa cttctcagag ggagaccaaa
     5281 gtagtgaagg ttcttgggct agtggcaaag cactggatgg cgaaggcgaa tatcaatggt
     5341 tgaaagaacc taagatcgaa ggcgctgcac caaaattaga accagtaaca ccaaaaatgt
     5401 atgggacacc tccattcaag aaataaatat ctacccgtag aaacacccgt tttttgttcc
     5461 acacgctttg tgagcaaaac tgactaaagt cattaatcat aaccaccctt caaaagggtg
     5521 gttttctcta gagctataag ctcaaatcac cggccagcgc ctaaagacgc tggctttcat
     5581 attttatgtt caagccatat tgcctttgcc agttttgccc acctcttaaa aggtttatgt
     5641 actactcctt agcccttaaa aggatcgtct tactctcgta cactcagctt atctaacgca
     5701 ctatcatgtt tttcttgttc ttgaatgtac tttttgatgg tcgcttcatt ttgtcctact
     5761 tttgtcacat agtatccttc cacccaaaag tgtcgatacc caaatttata ttttagattt
     5821 gcacaatctc ttgatgatct cctgaatatt ggctcgatat tgattataaa ttatttttct
     5881 tctatacttt ggtgtgaata caatgtggta tttacacatc tactttgtac gggctaaact
     5941 atttcccttt attgctccac ccgcatagca agtggttttg tatttcaatc gctcggcgcg
     6001 ctcaattagg tctaaagaca ataaatctaa aaacccgctg cttcactgac agaaacaacg
     6061 ggttttcaga aaaaaatgaa atgaaaaaga tctcttacgg caatctattt tatttttttg
     6121 attttttata aatggaaaat gcttcaagaa gtccaagaaa taaagccgta taaaaacaag
     6181 aacctatgaa atctttattt attagatatt caacagaaat cccgataaca ctagccaaca
     6241 atatatttat cagaagtgta aaataaggat gctttttata gaatagaact agtgttgttt
     6301 tcatagactc tcctttcttc atatttccaa ttaatcacaa attcacggca ttactagaaa
     6361 aattaaaggg gcgcagaagt ggaaaaatac tcttcgactt tccctacaaa ccaggccatc
     6421 ttgtgtttaa taactatacc aaatctaagg tacctctaaa tctaaattcc atttgtggcg
     6481 gtgacctcca atttttaact cttctatctc ccatccagta tacataacct tgatacttcg
     6541 accacttata tatcgaacac acaaatacct atccattgca ggagtactac ctaacttagt
     6601 tgctacttgc atctaaataa cagctgaaaa gataggactt actcttagta aagtatctga
     6661 actattaatt tttaaactat catttttatc ctcaactaca tgcacatctg ttgcaacttc
     6721 actttctgtc tcatccagat aaatgattaa ggaatcggga attgcaatat cttcagctga
     6781 cgctggaata gttgagctaa attagtcatc atatctttat tataaaataa ccaacagcaa
     6841 aaaatacaat gaaaaacaaa cttggaacta atgtatcatt aataaatgtt gaaaaattca
     6901 gcaactcatt actgtatgat tttagcagcc caaccaacat ataccctata aaagctaata
     6961 agatggttag gaatccttta gaatttttac tcattcatag acacttcctt aaataacttt
     7021 tattatagaa ggtattgtaa ataataatat tgacaaaaag tgactcaaaa taaaaaaaaa
     7081 cttacattat actggaatga actgtattga tagtgtacct aaaagctcta ctgacataag
     7141 atcgtgtaat cggtaaagta attttattaa ttatacggga tgtaatcaat tagagaataa
     7201 actaatcata aaaggtactt ttacattcat aattgtcgct ttgagattct actttggttc
     7261 actatctgac ccaattgcac attttcgatc attacaagta ttggtgtcgt tagaacaact
     7321 aaataaaaac tagcggtaga tttttcagaa tctatgctaa tttctgtatg gatgttccag
     7381 tgatggcaaa tttctctttt cattgttttt cttgtcgcat gatatgcctt tttgtgttat
     7441 tcagttaaac tatagaaatt ctttcctaga cagatcttga tcccaaattt tacgtttttg
     7501 agcatcgata tagtttaaaa tgacattact catatctaaa gagtttagat tttttaggac
     7561 taaaactgtc agttgttctt tttcttcttt ctgttaaagt attgtcgcga cttttcgtat
     7621 acgttaagat atgtcgtgaa aaaacaagtt ttgtgacaca aaaaaacgaa tgacttgagg
     7681 aaatcacctc aatcattcgt ttaaaatgct atatattctt tagtttaaga tacggaaatt
     7741 aatgccatcg accacactag tagaatgaac gacatttact tggccttttt ttaatttcgt
     7801 tatgtttagc atataaaaat attatagagt ttacttacaa tgcttaaaac atatactgta
     7861 taatctgatc aattttagcc atgtcttgca atggtaagtt ttctattttt ttgagttttc
     7921 gttccttaaa atcaagagat tttaattgtg taataattac ttgtcctttt atatctagct
     7981 cttcaggtaa tgagtaacgt gtcggtaaat tctttatagt ggaagtaatt ggacgtatga
     8041 ccgaaaacat tgttttacgg ttaaattcat aacgagagac gactagtcct ggtcgtcttt
     8101 tttgaatttc ttttcctacg gagggatcaa aatcaatcca tacaatatca ccttttttag
     8161 gaatataaat tctttcttct gacactataa aatttctctc ccttcaggag ttaaatcttc
     8221 ccattcgtct ttctcataat actcggcctc ttccccacca ctaaatggat cttcaatttt
     8281 tggaactaac gtaattgttc catcatcaga atacacaacg atatattctt ggttttctga
     8341 aggtttcttt ccgttatcag aaggtaaagt taccactaca gaacttcctt gtaatctaga
     8401 ttttgtaaca agcattatca tcactccctt aataaaagta tactatataa cactaagtaa
     8461 cgcaaaattc ccctttgtaa actatctaga aaattgtttt gtttaaagta tatcttattg
     8521 gatataaata gaaataaatt gtagccagtt cattttttct ttaaataaaa aaataatcca
     8581 agaaacattg aacctatgga tccaaaagct acccaaatac tatagctaac tccccgctac
     8641 cttcaatctt gcagataaaa cgctttggaa aaaaatcgag aaaatcgcaa agacgacagg
     8701 ccatcctatc atgcctgatt ataaacaaaa agctggctat tccttttgct ctgacaaatt
     8761 tcaattggga aagttcacga aactagcagg tgaagaagtt tcaactgttc ggattaaaga
     8821 atgcccgatt caaatagaaa cgttggttca acgaatttca actagagaag actttgctat
     8881 tgtagaatgt gagatcgtag ctatttttgt agaagaaggg attttacatg atccaactca
     8941 tatcaatgtg gataaatggc aacctcttat ctataaactc agagaatata caactgccaa
     9001 ccagtcgtta agtttgaatt ttagattcca agaattcaaa gagtcataat gataaacatc
     9061 attaggtata aataaaaaag actcgcagaa cgagtaaaaa acaaatagaa gctatacctt
     9121 agaaaggtcg actgtgactc tatagatgca gtatatgcag cttatgagca tttcttctgt
     9181 tctctttgtt tttgggatct gtgctgaagt ctttttcgtt ttttgccgct ctttctttga
     9241 aaaatcgatt atgttatacc ttctccatta ctaattcagg catctgttga gtaatgattt
     9301 ttcgcgcaaa agaaacatct gttacccaag gttcgatttg ttcttcagtc aagacaagcg
     9361 gcattcggtc atggattggt gcgactgtgc ggttaggttc agtagtcatt atgattgatt
     9421 ctgccatttt ttcatcctga tggctacgat aaaaaccgcc aatatacact attttttcct
     9481 tatttgaaaa cataaatttg tctttttctt cattccactc ataaaagcca ctcattggga
     9541 aaacacaacg attttgcaaa aatggttgat gaaaggtctt tttttcttct actgtctctg
     9601 cacgggcatt aatcatcaat tgtccttttt taaatccggt aaatccccac ttcatgattt
     9661 ccggagtgag gatgttttct tcctcttttc ttaacgtcac aacaagattt gacggaaaaa
     9721 cttctccagc tgctaattct gctgcctgct ccggttgttt cgtctgggct tctcgataat
     9781 aattctgaag gagctctgac tctagatcaa aaaaataacg accacacatc ctaatccctc
     9841 ccaatctttt tttctatcat acactgcaac aagaagtccg taccaacaaa acgctttcaa
     9901 tttgtgtaga actaaaaaag ttgtgacaag tgacaaactc tccagtgaat ggtattctcc
     9961 tgccaactcc tcggtcacaa gtcacaatat tcaacaaaca tgagaagctg ctttttgaaa
    10021 ttgttccttg tgactcggag tgaaacggca ggcttacgac ctctaggtaa acggtgttcc
    10081 agaagtagct tcttcgaaaa ataagccgaa atttcacaaa aatttgagaa gcaattttcg
    10141 taaattcctt cttatttctt gaagctgacc acttctgtca caacctctaa ttattaaaga
    10201 accttttgcg aagttaacaa tctttctttg atcaattgaa aattttgtct aagtagtgat
    10261 agatcctgtg tgactttcaa caataagata cttccctgga tttcagcaat caacgctttg
    10321 gcttgacggt ctgcttcttc atcggacagt ttttcttcag aaagtgccag gatattttgt
    10381 ttcgtatact tgatccattg attgactaat tctagtagca acagacggta ttcttcatcc
    10441 actgtactca actcaataat caaattacct acaggacagc catgataagt gatctgtgtc
    10501 tcatgatcag caaaaatcca gtccaacatt tcttctaatg cttcttctgg ctgttttcca
    10561 gcatttaaga tgtcttcgaa caattctgtc tgccacacga ccatatgcgc atggatcacc
    10621 gctagacaaa cttctttttt tgaagaaaag taataataaa attgcccttt ccccgtctca
    10681 gaagctgcta gaatatctcg gattgacgtt tcatgatagc cttttttata aataagatct
    10741 ttggtcgctt ccaagatctt ttcctttgtt ttcaatgata ttctcctttt tcatttctca
    10801 tagtcctata ttatacaata aattcatcat tttttcttct taatcgttta aaaaagactg
    10861 tgccaaatta tctgacacag ccctcactat aaaactgttc tcatatagct agatgttcat
    10921 tgattcaaga actgcgagga caaaagcaat tcctatctta tgatagttgc tctaatactt
    10981 cctctgttgt catcacttga tctgcaataa agccaaagtt cgtcaacgct gcatccattg
    11041 cttcttgacc aggagcacca attgcatctg tcgctaccac aacattgaat ccactctcta
    11101 ccaattcacg catatgggaa tcgctacaca agtttccgtt cattccacca agaatcactg
    11161 tgtcgattcc attttttctc aattggagcg ccaaatcatt gctttctggt ccaaagattt
    11221 tatgaggaga gctgataatc gtattttcat ccaaatatgg tttcaattct tcgatgaaat
    11281 cagctcctga accttcttca actgattcat attgactttt cctagcaaac atctgttgct
    11341 caagcatcat atgttctcct gcaccgccaa attgccattt atggtcatgt gggtaaaaat
    11401 aatgaggaga aataaagagt ttgtatcctt tttcttttgc ttgtttcacc atttcgatca
    11461 tgttttcgat cgtattgtat ttttctaaga tatcttttgt caaactaaag ccaccgcctg
    11521 ctggtttcaa gaactcgact tgcgggtcag tgagaactac tgctgtattt ttattattga
    11581 acatggtgga ttctccattc gttatttatt ttaatacatc atttaaagct tcactcattg
    11641 ttggatgaga atagatttga tctctcaata acgtataagg aagttttcca ttcatagcta
    11701 gcgaaatcaa gttgatgact tcatgagaat cttccgcata gatacttgcc cctagaatca
    11761 agtcagtttc agggtcgact aaaactttga atacaccttt aggatcttct aatacttgtg
    11821 ctttagggac accgcttgtc atatacttga ataatttgta attgacgcct tgtgctttgg
    11881 cttgtttttc tgttaaacct acattggata aagtcggagt gataaataca ctgtaaggca
    11941 cagctttccg gttattcgtt gttcgtttat tctcgccctt caactgatcc ataatgattc
    12001 gataatcatc tagagagata taagtgaact gcaatccgcc tttgacgtct ccaatcgccc
    12061 aaatgttgtc tgcatctgta cgaaggtatt catccacagc gattgctccg cgatctgtta
    12121 gtttaacatc tgtattttct aatccaagtg atgctgtact tggttttctt ccagttgcag
    12181 ccaaaacttt tgacgcttgg attgttactt cttggccatt ttctgtaaag gtgacggcag
    12241 ctgttgattc ttggtctgct acttgatcta cagatacacc tagatggaat tcgattcccg
    12301 catttgtcat gtcttctaaa atcatttgcg cgatatcttc atcttcacga ggaagaaatt
    12361 caggatgggc atcaagaacg acaactttag atccgtattc attgaacatt gatgcaaatt
    12421 ccaagccaat atatccagcc ccgatgatca ctaatttttc cggtaattgt tcctgatcca
    12481 tcgcttgcgt agaatcaatc aagtagcgac ttgtattcaa tcctttgatt ggtaaaatga
    12541 ttggttcaga accagtattg atgaaaatcc gttcgccttc aacaatcact ttttcaccat
    12601 tattcgtcac ttcgatttga tggttagaaa gaaaacgtgc tgtaccgtcc atcactgtcc
    12661 cagttgcctc atcgctgatc atatgataat ttttggcgcg aagcatgccc gtcaattttt
    12721 ctttccgagc aacagcctct gtaaagtcga ttcctctttc tccattgaaa atcaatgatt
    12781 tagaaggaat acagccgatg ttgatacatg ttccgccata catacgtgtt gacttttcaa
    12841 cgactaaaac cgattcgcct tttgaagcta acgccttcgc taaagtctta ccgccctttc
    12901 caaaaccgat cacaatattt tgatattttt ccatcctttt tccctcgctt ctttttttac
    12961 ctaccgattg gtacaaaaat atgataaccg ataattgtct attctccaaa tcatctgctt
    13021 tatttgtcaa aaaaaaccag acaaaaagcg gtcctttcac gtttttagtc tggttcgatt
    13081 tcctttattc ttctaaacaa tcgttacttc tacatcgata tttcctctag ttgctttgga
    13141 gtaagggcag aattcatgcg catcttctgc aattttttgg gcttcttctt cgctgatgcc
    13201 atcgatatgc acttctaata ctacaccgat ctgatagccg ccatcatcta aattataaag
    13261 agagacacgt gcttttactg tggactctgc tgtcattcct gcttctttga tcatatgttg
    13321 taccgcccca ttgaaacaag aagcataacc tgctgcaaat aattgttctg gatttgttcc
    13381 ttctgcatgg attcctggag gagtgatttt catatgcatc gagccatttg gtgcctcgac
    13441 ttctccattg cgcccgccat ggttgatcat tgctgtttcg tatgcttttt tcattgtact
    13501 gctcctttcg attgaccatt tgctacttgg ctataattat agtgtatgac aagtaaggcg
    13561 ctttctacaa aaattctgct tattcgaata ccagaatgcc gtcttctact atttttccaa
    13621 aaaacaaaaa aatactactc gtgaacaaca gcgtcatatt tgttccaaaa taaatagcaa
    13681 tcttttctac ataatctttt atatgattga ttttaagata catatatacc agaaagttga
    13741 ccccataaac caatactgtt aaaaaaataa ccatattcgt taccattttt tcctcctttt
    13801 gctggtctcc ctaccagcac tcgatttaac cataccactt tttttgccgt ccaagcaact
    13861 agcctttcaa aaagactggt ttattctgct gttaatgatt caagatcaga aaaatgtccg
    13921 aataattttg ctaattttac taacgccaac ttgttctttc cgaattcatc attttctatc
    13981 tgtaatacta gtaacggctc atgtaagctt aaacggatca aaaaccagcc gtttccgtat
    14041 ggctcttcta gatcatatcg aataccttct tcattttccg ggtcgaagtt catccctttt
    14101 tcttcttcca acagtcgctt catttcttct aatatcttgt ttccttgttc gcgtggttca
    14161 tcgctgaaca attttaatcg gatttcttgt acttctacgg gctgtttcaa ctctttgatt
    14221 tgttcatcta atgtgatacc ttttcttttt aattctggca aaagcatcag gatctttgcg
    14281 atgacatatg caccatcatc cagaaaatag ttttccttga atgcagcgtg tccgcttgtt
    14341 tcgatggcta gctgtgtatc tttcccaaga cggttaagtt ctaatgcttt attgattaca
    14401 tttcgatagc cggaaatata acgaacttgg atgcctcctt tttcttcaat gaatctttgt
    14461 agatgagaag aagtagggga attcgtcacg attcttgttc ctggatgctc ttttaatacg
    14521 attgtactta atactgcgat caaattattt cgattgatca ctgttccaga agcactgaca
    14581 actgcagaac gatccacatc tgtatcgaaa atgatcccaa gatctgcttc atttgctaaa
    14641 acagcctgct tgatactttc catcgcttct ttattatcag gatttgggat atgattagga
    14701 aatcggccat ctggttccaa aaattgggaa cctgttgaat ccgcacctaa gctattcaat
    14761 actttttcag caaagaatcc accagcacca tttccggcat caacaatgat tttccaacca
    14821 tttagtggtt tgctttctag tgttccaatc ccctttttaa tttttgtgac taaatcttgc
    14881 gcataaggtg tcaaaaggtc tgctttttct acgcttccag tttgttcgct ttttattttt
    14941 tgctgctgtg ataggataaa agcaatatct tctttttctg ctcctccttc tgaggtaaag
    15001 aattttattc cattataata atagggaaga tggctagcag tcagcataac cgcagcatcg
    15061 cacgagaact gttcaaattg agtggacata aacatagcag gcgtagtagc taattcgaaa
    15121 tcgatgacat gtatcccttg ttctttcaga ctttggatca acgcctcttt cagtgctggt
    15181 ccgcttatcc tactgtcatg accaatccca atcgtccatt ttttatttgg atcggttgat
    15241 ttcttctttt tctttatcca gtttgctagt ccccagccga tcttttttac catgtctgtc
    15301 gtcaagttta cttcatatcc ttcaactggt aatgcgattc ctcgaatatc cgatccattt
    15361 tgcagcgctt tcatatcttt catataaaag tcctcctcat ttattccctc attttttcca
    15421 gcttttctgc aaatcgctgt gcttcttctt ctgagcggca aataataatg aatgtatcta
    15481 caccggccat cgttccgaca acttcagggt aagccacttc atctagccaa ttcgttacca
    15541 catcggcacc atttcgttca gtcaatacga taaccatgaa ctgaacagac tggatacgca
    15601 aaacctcgcg tctaattgct gtacgcaaac gttcttcatt taaagaaaca gatggctggt
    15661 taaataatgt atagcgtact attttgtttt cattttgact ttttactaac ttcatttctc
    15721 gaatgtctcg agaaatcgtt gcttgagtca catcggcgcc tgcttcatgc agccgcgcaa
    15781 gcagctcttc ctgtgtccca ataggttgtt ctgtaatgat ctggcggatc agtgcttgtc
    15841 gctgtttctt tttcatatta gacacctctc aatgttgatt atagcaaaag ataagtaata
    15901 tttcttcata ttttggtatt ttttactttt attttttgtt ttcattcagg ttgctaacct
    15961 ttttctattt taacacgcaa aatcgtcttc attttttcag gtgctgattt tcttggatcg
    16021 ctgatgtaaa tctctttgtg ttctttagaa gctctttcat agccttcttt tgcgatgaat
    16081 gcttctaatt tctcaaacgt tgctggttct tcggcatagg gcccgacgtg taagatttgg
    16141 gcacaaagac cttcttccat ctttttgaat actacttgtt ctttcaagtc ttccggaagt
    16201 ttgctagaac gctgaatggc ttcttgtgct atcgcttctg taacaaagtc aggctgtcgg
    16261 atcatcaatt gataagaaaa atgttctttt ttcatcactg gttcatgcaa atacttttct
    16321 tgcagtcccc attgtccttc cagtggatag acagtataca tctgataatc aggaatcagc
    16381 caattttttt taggcgacat gcgtattgca tagctgactg catatagaca ggctactctt
    16441 cgtttaaagt cttcctgatt cgggtcgccg atccctctga tgctaaagaa tgatttttta
    16501 ggaacctcta gtatttgcgg gctttttttc atactatagc tcttgtcttt acgccattca
    16561 attttttcca tttttcttcc tccgcgaaat tccatttagt tatttattat catacctctt
    16621 tttgagtgac ttggctaatc gtgttgacac tatttttcag tttgtgctag aataagtgaa
    16681 gtaaataaat cgtacagata acacgtttcg gcgtgtcgag agagaggcgg tttctatttt
    16741 tataatagaa atcactctct ttttttacga aattttttag aggtgatgta aatgacaaaa
    16801 caaaaacagc tgcttttagt acctgcagta attgcaacag ggatgatgtc ttttgcgggc
    16861 gtattgatcg agacggccat gaatgtaact ttcccaactc ttatcagaca gtttgattta
    16921 acgactgcac aagtccaatg ggtaacaacg atttatcttt tgatgatttc gatcattgtt
    16981 ccgctgtcta cttatttgaa tcgcaatttt agtctcaaaa aactcttttt agcttcaaat
    17041 ctgcttttct tggcaggtat aatgatcgat ttcttctctc ctaccttcat ggtcctattg
    17101 tttggtcgat tgctccaagg tgcagcgaca ggtatcgctc ttccgttgat gttccatatt
    17161 atcttgacat ttgcccccct caatcgacga ggcgcgatga tgggtgtcgg tactttgaca
    17221 acggccattg ctccagcaat tggccccact tatggaggca ttatgacttc acattttaca
    17281 tggaatcata tcttcctgtt tcttgtgccc gttttgattc tttctttgat tatcggctgg
    17341 tttgctattc ccgagatggc agtacaaaaa agtggttatt tggattggat aagcgtttta
    17401 ggaatttgtc ttttgtttag tggaagtcta acatttttga gtacgttggg aacagtttcc
    17461 agctggattg ctttaatcat cggcggtatt ggctggttcc ttttttacta tcgaagtaaa
    17521 aaagtggagc atccactgat ccgactgtct attctttcaa ataaaacatt ccgcttgttt
    17581 ttgattggct tcttagttta tcagttttta ttacttggtg tatcttttgt cttgccgaat
    17641 ttccttcaga tcgttcaagg aagtagtcct tttgtcgctg gattagcgat gcttcccggc
    17701 gcagcggttg gtgctttgct ttctcctttt tccgggaaaa tgctggatca atatggtccg
    17761 aagaagccaa tttttgctgg gctgattctt tctttgattg gttggctagc attattccta
    17821 ctcataggac acgcttcagt gggtgtattg attgcttgtc atgtgtttta tatgatcggt
    17881 atcggattat cttacagcaa tatgatgacc accggaatga atgcactgaa tgaagaacta
    17941 caaggagacg ggaacgcaat gttcaatacc ttgcagcagt tttctggcgc tgtggctact
    18001 tcattagtag cggtcattat caattacgtc cagcatcata cttcccataa ctatgaagtg
    18061 tctactacat taggatcaaa agcagcatta ggcgtcttgt tgctgttgct tctcgtaagc
    18121 tttgctcgat tcgcctatta tctgttcttt gctaaaaaag cgtagattcc atatacggca
    18181 ggtgttgcat ctgccgtttt tttgtgtgaa aatggttgtt tgtaaaagga ggctttttta
    18241 tggaaaaaat tgccattatc ggtggcggga tcattggtat gaccctagcc agttacttag
    18301 atacatcaaa attcaatgtt gctttatttg atgaagggac aggacaggca actaaagcta
    18361 gcgctgggat tatctcccct tggttgtcga aacgcagaaa caaacaatgg tatcgtctgg
    18421 ctaaagacgg cgctgctttt ttccctaaac ttataaaaga tttccaactt gatcaaacga
    18481 tttacgcaca atcagggaca cttttgcttc gacctgaaaa agatttagct gaattggctg
    18541 ttcttgccga gaaacgaaaa gaagaagcgc cagaaattgg aaacatcgaa tggctttcac
    18601 ctgaacagac atctcaagca cttccgttat tgaaaccagc agtttcactg cgtatcagtg
    18661 gtggtggtcg tctggatgga aaagcatatt tagaacatct tggtcagcgt ttagcacaaa
    18721 aacaaatgga gcagatccag gcaaaagtca ctttgcataa gaagagcgat tcttggctca
    18781 tcaagggacc gtttggagaa tacacagctg atcgtgtaat tttgacacct ggcccggcac
    18841 ttaagccttt attacaagaa ttaggctatg ctgcagatat acgtccgcaa aaagggcagc
    18901 tcttagcatt tcagacatct tataagatga gtcaagactg gcctgttgct atgcttgacg
    18961 gagaagctga tttcattcct ttcatggatg gaaagatcct tttaggtgct acccatgaaa
    19021 acgatcaagg ctgggatttg gctcctacta gcgaagctta taagggattg actaagagta
    19081 cagaacagtt cttgactgat ccagatcaga taaaaaactg gccatacgag ttccgtgtag
    19141 gtacccgtgc ttatacgtca gatttttccc catttttcgg cgtactgcca gatgatccaa
    19201 gcttactggc tgctagcggt ctaggctctt ctggcttgac cacaggtcct tatatcggct
    19261 atctattagc caacttctta aatactggtc attggcctac ggaagattat caaaaggaca
    19321 tctccaccta tattacgaaa aatccatcat agaaaaacag ctttttcaag taaggatccc
    19381 gagcgatatt gcgcatggat tacttcttga aaaagctgtt attttagttc aatttctgaa
    19441 tcaaattctc caaactttct tttgcttcat ctggcaagag atcttttcct atctgagctt
    19501 caatgaatcg taaacgaata tcaagtcgtt gtttcaccag atttttatag gacgtatcct
    19561 caaaagaaac aggaaaatct ggtataggta aatagtggat gtcttcaaat ggaccaaacg
    19621 acttgaattc tgccgtttgt tgcacgattc tttcaacgat tgacaatgtc gtttcaggtt
    19681 tgattttttt atcatcgaaa tatccagtat tcaggacata gcaggctgtt tgctgtttca
    19741 aaaacaactc tcgaaaagct tgatagtctt ccctaagagg atagacacgg aaaggattag
    19801 caaatggttc aatgactagc tcatctagct gtctttttgt agtgatattt tccgcgtctg
    19861 atcgttttgt tgctaatgtt gcaccaaaag acgctgctaa aactgggtca ttgatcttga
    19921 taattggcgg aagcgaatca tctttcatga tccaaaaaac agcatcgatc ttttcgctaa
    19981 gatgatcgac tcggtcgggt gtcgcataac gtgatttgac tgtccgccca tttccgtttc
    20041 gtatatctcc tgttactagg actttttctc ctttacttgt acatgtcacg cccacattct
    20101 gacaagtaag gaaagaagaa atggccggat catcagacgg atagtcttgt gttttatcaa
    20161 agtaagaagg ttccaaggca gtagcaaaac cattttttcg agaaataacg aaagcatcgt
    20221 catgcaagat cgaaacagag tgaccttccg tatgttttgc taaggtaatc gttgattttc
    20281 cagaaccgga caacccaaat acagccatcg tataggtctg gtcattacta gcatattgtt
    20341 tcatcccacc gtggcaggca ataaagccat tgcgatttcc caatgcccaa gcaagcgtca
    20401 aagtcgcttt ttttaattct ccaaagtaac gtaatcctag cacagccgct gtattatgga
    20461 gagcatcaaa caaaatgagt ccatttggaa atgtttcatg tgtccattcg ggatcacaaa
    20521 agatataaag atctccctca tcaaaggaaa cagacttttg ataagtctct aagatcttcg
    20581 aattcgctgg ctgaaaattc agcaaataag aatacaaatt gttctcaaat ccttctggaa
    20641 tcagcaaatg actttgcaca gaaaattctt cagataggcc aacgattact tttgtatggt
    20701 aaaactggcg cttgcgactt tgatacacag cttctcttaa aattttctcg tatttgcttt
    20761 gttccttgtc taagtcctca aagatccgcc gagcacttgc tgttcttccc acaatgcttc
    20821 catcattgaa tactagtgtc ctaacatcag ctggtaaatc tagttcttca gcatgtgaga
    20881 ttgttaaatc tgtgatgatc gttcctggac tcccttttgc tagttgataa gctgtcttcc
    20941 tatcaaaaac ttcatgaaca ttattaccgt aaaatgtcgt ttctacaatc gatcgaatac
    21001 tggataacag tggatttcca cttgtgattt cgtttaattc gagactctct tttgtactca
    21061 tggctcctcc tcattcccta aacaaaaaaa cgttttcttt attatacatt attcgagttt
    21121 ttatttgtac tgctgcgctg tgggaagcaa acgagttatt tttcacacaa aaaaaccgag
    21181 aacttgaata aacaagtttc tcggtttcat cattttcctt ttatcggctt agtaccagcc
    21241 gtttgctaac cagaatgttt tagcagcatc ccatgaacca taacgagatg ttacatattg
    21301 ttctgctaca cgttcttgat tggcagctga atagtcgccg tttaagtatg aagcatctaa
    21361 ttgataacgg ccgatgtaac gtccgttagt agctgtgtat gaaccgcctg attctttttg
    21421 tgcgatccat tcttttgcag agcttgaagt tggcgctgtt gcagcagctg gggcagcagg
    21481 agctacttca actgtttcaa caggtgcaac gtatgtatgt tcttgcgttg ctgtttcagt
    21541 tgtagatgct gtattttctg ttgttttgtt ttctgttgtt gctgaagaat catttgaagt
    21601 tgggattgtt aattgttcac caacataaat gcggttgatg tttgcgatcg aatttttttc
    21661 agcaattgca tcgatcattg agttgtctcc tgcaaatttt tgtgagatct tagataatga
    21721 atcacctgat tttactgtat aaacttcatc agcgtgagca tttgtagttc ctacaaacat
    21781 tgcagtagca ccagcagcaa aagttgtacc taaaacaatt ttcttaaatg aattcatatt
    21841 aaactccttt ttttctccgt tttttattct ttcgacgcta ttaact
//
LOCUS       DAXLPC010000045        21625 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.045, whole genome shotgun sequence.
ACCESSION   DAXLPC010000045 DAXLPC010000000
VERSION     DAXLPC010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.045"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            4..750
                     /locus_tag="ACF3UE_001603"
     CDS             4..750
                     /locus_tag="ACF3UE_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635009.1"
                     /translation="MFLVIGTILVIQLSGCRNKDKDFYGYWSGTAEKIPVDYNFKITK
                     DRVIELQKNGEMVDFKYTLRHKKFDSTTFRSIMISKDELVKAIPELKETTGISNITFM
                     PIDGEKDKLTVLVNLDEHLSTATLYRTTKDESPIGKVEKKNDTISRQTVDKKIDTFIK
                     TYAAIPPTWKLVNEDKGITINTDTEIPTDAQSLSDLLANLTGVSNAVSEQVGKDIPLR
                     LLENGKKDYSVVFKNGKVTDYNEIFEKVIE"
     gene            2506..3291
                     /locus_tag="ACF3UE_001604"
     CDS             2506..3291
                     /locus_tag="ACF3UE_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006701865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylase"
                     /protein_id="HFD3635010.1"
                     /translation="MVEDMVMVEEEQGRLIKSKKRVQKHGEVFTPQRTVKDMLDLPGI
                     KEACEELQTTFLEPSAGEGAFLVEVLTRKMAMVAREYNESLEQYENYSLLALSTLYGV
                     ELLEDNAQTCVMNMFQVFNDLYREQSKKHGTAMKRKVQDSAKTLISRNIKQGDFLTKR
                     TPDDNPIIFSEWTPKTLRKGQKKITVNRTEYSLEDIYSGVTREFGEAYSALPVFEQLD
                     LFSFDDEVDEEVSNDPILRYVAMPITEVYKEEMEEIDDDSVEI"
     gene            3269..7666
                     /locus_tag="ACF3UE_001605"
     CDS             3269..7666
                     /locus_tag="ACF3UE_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019788126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HFD3635011.1"
                     /translation="MTTALKSKAKYFDYLPKYGSKLEHFLGIPNLVDAINTYRVTVNQ
                     IPNEVAIGTRRYSEVAARKIASNVGIDQQSMKYVDVLRELRVRNNITPTIADLFHKLR
                     KYGNVAAHENGIIPVSEAVESLVTLDTLLRVFARNLSGDKSLNPKEEITDEMFVITYN
                     TFDRKLIYIQSAKDADGTWKMYQGLEKIGDASVPENYEADFTPNSEYLREYASRRIKQ
                     YMTTAGVPFVLHWAQLAVNKKNQFFRDHDVHEVLKRSGYNPQTIGEDDTGKPNEWFSV
                     TVDVAKKAIQAVKDGKGSLDSEKDDFDEFKINFRPEQKDAIEQTKTVFKTKDEMLWNA
                     KMRFGKTLSSLQVIKESQYKKVLIMTHRPVVSDGWFTDFKKIFTDGSYIYGSKQDGEK
                     IQNLVDTEKPFIYFASIQDLRGSEWAGGKAGDKNYEFLAIDWDFIIIDEAHEGNETEL
                     ANNVKAKLRKEHTKVLELSGTPFNLFDKYDEDNIFTWDYTMEQEAKEKWSVEHPNEPN
                     PYEGLPKVSMFTFEIPNKFDYFDENKAFNFREFFRVKEDDETKLLHEGDVRKFLDYIT
                     TNDEKTNFPFSKPEFRENLRHTLWLMPGVKEANAFERVLETHPIFKDYNIANVVKTGD
                     SEHASDSDLELVRKAIGNPAKSKTITLTVRKLTTGVNVPEWTGVFFLSNTESPTSYLQ
                     AAFRAQTPFNHAELGIKKNCYIFDFAPDRALKIMSGSVGLTSKKGKVNSSEQKKKLER
                     MLNFLPILGKQGNVMKEFSVDRMLTALKKAYAEKAVRTGFEDSSLYNDNLLNLDQADL
                     TKFEDLKKIVGSSKPTKVKDFIVSDNGMSEEEYEKASRAEKKPKRQRTKEEQEAIDRA
                     KRLREQRNKMISILRGVSIRIPMMIYGMDIDIKDDVTIEMFLNLVDEASWNEFMPEGL
                     SKGRFREFIEYYDADVFVEAGRIIRRRAKSYDELDVIERTRKIGELFSTFKNPDKETV
                     LTPWRVVNMHLGNTIGGLSFFDEEYQNSTENGQPIVRWRKTDCTDDIFKENRKILEIN
                     SKTGLYPLYAATSMYYVQLLKQSDINAGRVDSEAIWEKVLSEQIFVISKTPMAKTITK
                     RTLIGYNAWKVNVEYSSELVTSMKRSINDGLTNLKGVYKNVKFDVIIGNPPYQEKDGG
                     SGASATPLYNLFVETSVKLSERYVSMITPSKWFAGGKGLDKYRDFMLNSSSLKVMVDI
                     VNGKEIFPNTSIGGGVSYFLWDKKYNGLTQYTNQHDGVSNTQERKMNEFPVFVRYNEA
                     ISAIHKIGEHASVGDFVISRNPFGLPTKIRGEEVQDSRNSIKVISSGGVGFVPLEDIT
                     KGQDMVGKYKVISSSLTSEHAGEPNKNGMFKVISTNRVIKPNEVVTDSYLVLFSADTE
                     TEAINYLKYLRTRFYRFLLLQAVTSIHLSKDKFMFIPVQDFTSGSDINWNVGIEEVDM
                     QLFKKYSFDASEILFIDQTIVPILHEEYY"
     gene            complement(9106..9771)
                     /locus_tag="ACF3UE_001606"
     CDS             complement(9106..9771)
                     /locus_tag="ACF3UE_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635012.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            9897..11933
                     /locus_tag="ACF3UE_001607"
     CDS             9897..11933
                     /locus_tag="ACF3UE_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HFD3635013.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            11937..12575
                     /locus_tag="ACF3UE_001608"
     CDS             11937..12575
                     /locus_tag="ACF3UE_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635014.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            12603..13031
                     /locus_tag="ACF3UE_001609"
     CDS             12603..13031
                     /locus_tag="ACF3UE_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635015.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            13488..14399
                     /locus_tag="ACF3UE_001610"
     CDS             13488..14399
                     /locus_tag="ACF3UE_001610"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3635016.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            14616..15053
                     /locus_tag="ACF3UE_001611"
     CDS             14616..15053
                     /locus_tag="ACF3UE_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635017.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            15148..16032
                     /locus_tag="ACF3UE_001612"
     CDS             15148..16032
                     /locus_tag="ACF3UE_001612"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFD3635018.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            16256..19423
                     /locus_tag="ACF3UE_001613"
     CDS             16256..19423
                     /locus_tag="ACF3UE_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFD3635019.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            19491..19988
                     /locus_tag="ACF3UE_001614"
     CDS             19491..19988
                     /locus_tag="ACF3UE_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HFD3635020.1"
                     /translation="MILLLGFILWQTPVHASEFNFAVDFELPANQIDKNKTYINVRME
                     PGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAK
                     TVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQV
                     KAILI"
     gene            20007..20471
                     /locus_tag="ACF3UE_001615"
                     /pseudo
     CDS             20007..20471
                     /locus_tag="ACF3UE_001615"
                     /inference="COORDINATES: protein motif:HMM:NF023225.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
     gene            20468..21226
                     /locus_tag="ACF3UE_001616"
     CDS             20468..21226
                     /locus_tag="ACF3UE_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFD3635021.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(21312..>21625)
                     /locus_tag="ACF3UE_001617"
     CDS             complement(21312..>21625)
                     /locus_tag="ACF3UE_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HFD3635022.1"
                     /translation="LVLYPREILYIESIKGLKNQVMVKTTTEDKLVNTSLKQLKTELE
                     KYAYFLLLKSYCINLSQLQKIDSAHYVLEFFNGDSLLVGRKIFEKTKERFHDFQKTAS
                     S"
BASE COUNT         7408 a         3432 c         4464 g         6321 t
ORIGIN      
        1 ggtatatttt tggttatagg aactatactg gttattcaat tatcaggttg tagaaataaa
       61 gataaagatt tctatggata ttggtcagga actgctgaga aaattcctgt agactataat
      121 tttaaaataa ctaaagacag agtaatagaa ctacaaaaaa atggtgaaat ggtggatttt
      181 aagtatactc taagacataa aaaatttgat tcaactacat ttcgttcaat catgatatca
      241 aaagatgaat tagttaaagc gattccagaa ttaaaggaaa ccacgggaat aagcaatata
      301 acgttcatgc ctattgacgg tgaaaaagat aaattaactg tgttggtaaa tttggatgaa
      361 cacttatcaa cagccactct ttataggact acgaaagatg agagtccaat tggtaaggta
      421 gaaaagaaaa acgatacaat atcaagacaa actgtagata aaaaaattga tacgttcata
      481 aaaacatacg cggctatacc acctacttgg aaacttgtaa atgaagataa gggaataacg
      541 ataaatactg atacagagat tccgactgat gctcaatctt tatcagattt attagctaat
      601 ctaacaggag tcagtaatgc ggtgtcagag caagtcggta aagatattcc acttaggtta
      661 cttgaaaatg gaaaaaaaga ttattctgtg gtatttaaga acggaaaggt aactgattac
      721 aacgaaatat ttgagaaagt cattgaataa tggtttttct atctttttat taactaccct
      781 accccgttgt tttttgaccg tgtttcgaga ggaatcatta gaaagcatag gctaactagg
      841 ggtttctttt tcttttattt tttgggaatc cgcttaagtg aaatgtatct gaaatgaaac
      901 ggagataaag tgattttttg ctgtaatgac aaggttttag ctgtttcaga taccatgtaa
      961 cccaaaatag tttattgaga aaataggaga gtatttgata ctaactagta gggaaaaatg
     1021 agataaaaag taaatggaat catttcaggt aatctgaaat aaaaaaatat acagtcctgt
     1081 ggcactttac ctatgggact gtatattttt tactctcagc gttttttgac tccgtgtctg
     1141 actccgtttt attgatttta tatgttattc agtgaccctt taacaggtca atttttatgt
     1201 ttttgtcttc gtatgactca gtttgatacc tagtgatttc catggtaata cgggatgttg
     1261 aacaagctag agaagttctg caggggttaa ttgcaaacaa ttcagataaa caaattacaa
     1321 tagattattt caagagggaa attaaaaaat cagaggaaaa atatttagat ttaaagtcgg
     1381 atatcctatt agcagacgat ataggttcac taactgtcga agaagatagc ctattctacg
     1441 tctattgtgc attgacttcg taaaagaaga cgtcttttcc aggtatacag ttcttttatc
     1501 tacttcatat gaaaatttgg gtacaaacga caaggaagtc agttttctgg tcagactatc
     1561 gtacgaacat cttgttgtgg tatttacact cagctttgat gatgagtaca agagtttttc
     1621 agcgaacaag acagaacatc gaaagaggtt tccagacgaa gttttacagg ctgggctgaa
     1681 gtattatcaa gaaggactca ccattaagaa gtctttatcg agaatataag aagatacagg
     1741 tatagaagtc agtcggtcaa cattctgtga ttacctaaac agcaaggagt aacaggtgaa
     1801 cgggaaaaag agcacaggga gggctatgtt cactggctga agaagcaaga taaacctgtt
     1861 tatgacttgt tctttgaaat aaagaaagct ttagatagtc agtcattaga gaacttcatt
     1921 gatgggtatg atgaaaagtt atctaatgag caaatgattg cgataatgaa agaggtgttt
     1981 cgtcagtatg ggttatcaaa taaacgtagg aaagaggttt ttgaccacgt taagacaata
     2041 atgagctttt accacacgac cctcggctaa atctaaagag ggcgaaaaag ggacgagtgg
     2101 taaaatttaa tgggaatagc taaaagtaaa taataataag tcaaagactg cctagtttgg
     2161 tggtcttttt tcatgttcat aaaaataaaa taggacagac gaacatcttc gctaactccc
     2221 ctgtgttgca agaggcaaac tctataattc tccagttaag ctatattttg ttctttattt
     2281 tgagatagag gaaaaaacaa aaatgtgtta aaattgaaca taagcataat tagaaattgt
     2341 cgagtttttt caagtaaaaa tcttgacttg taaggaggaa aagggcatga tgacacgcaa
     2401 tcacagtact agccagcagt ctgcccaaaa gcccatatat gaaagtgata accgattcgt
     2461 agcatccgtt tcggttattt gtgttgggaa gatgggtgat ttttagtggt tgaagatatg
     2521 gtgatggttg aagaggaaca aggacgacta atcaaaagta aaaaacgtgt ccagaagcac
     2581 ggtgaggtat ttacaccgca aagaactgtc aaagatatgt tggatttgcc aggcataaaa
     2641 gaggcttgcg aggagctgca gacgactttc ttagagcctt cagctggaga aggtgctttc
     2701 ttagttgagg ttttgactag aaaaatggca atggttgctc gtgaatataa tgagtcccta
     2761 gaacagtatg aaaattactc cttactggcg ctttcaactc tatatggcgt ggagttactc
     2821 gaagacaatg ctcagacctg tgtaatgaac atgtttcaag tattcaacga tttgtacaga
     2881 gaacaatcga aaaaacatgg taccgcaatg aaaaggaaag tccaagacag tgcaaagact
     2941 ttgatttcta ggaatatcaa acagggagat tttcttacaa aacgaacacc agatgataat
     3001 ccgattattt ttagtgagtg gacacctaag acgctaagaa aaggacagaa aaaaatcact
     3061 gtaaatcgaa ctgaatattc tttggaggat atttattcag gggtaacacg agagtttgga
     3121 gaggcatact cagctctgcc tgtatttgaa cagctcgatt tgttttcatt tgatgacgag
     3181 gtcgatgaag aagtttcaaa tgatccaata ttacgttatg tagcgatgcc gataactgag
     3241 gtttataagg aagagatgga ggaaattgat gacgacagcg ttgaaatcta aagctaaata
     3301 cttcgattac ttacctaaat atggttctaa gctagaacac ttccttggga ttcctaattt
     3361 agtagatgca attaacacgt accgtgtaac cgttaatcaa atacctaatg aagttgctat
     3421 tggaactaga cgttattcgg aggtagcagc acggaagatt gcttcaaatg tgggtattga
     3481 ccagcaaagt atgaagtatg ttgatgtact tcgcgagctt agggtcagaa ataatattac
     3541 tcctacgata gctgacttat ttcataagtt gagaaaatat ggaaatgttg cagcacatga
     3601 aaatggaatt atacctgttt cagaggcggt cgaatcttta gttactcttg ataccttgct
     3661 aagagtcttt gcacgcaatc tgtctgggga taaatcgtta aacccaaagg aagaaattac
     3721 ggatgagatg tttgttatca cctataacac ctttgaccgt aaacttattt acatccagag
     3781 tgccaaggat gctgacggca catggaaaat gtaccaagga ctggaaaaga ttggggatgc
     3841 atcagtacca gagaattatg aggcagactt tactcctaat agcgagtatt taagagagta
     3901 tgcaagtaga agaataaagc agtacatgac aacagcgggg gtaccttttg tccttcattg
     3961 ggcgcaattg gctgttaata agaagaacca atttttccgt gaccatgacg tgcatgaagt
     4021 attaaagcgt tcgggctata atcctcaaac gattggcgaa gatgacacag ggaagcctaa
     4081 tgagtggttc agtgtaacag ttgacgttgc caagaaagca atccaagcgg ttaaagatgg
     4141 taaaggtagt cttgactcag aaaaagatga ctttgacgag ttcaaaatta attttagacc
     4201 agaacaaaaa gatgctattg agcagactaa gactgtattc aaaacgaaag atgagatgct
     4261 ttggaatgcc aagatgcgtt ttggtaagac gctttcttct cttcaagtga ttaaagagag
     4321 ccaatacaaa aaagttctta tcatgactca tcgacctgtt gtaagtgatg gttggtttac
     4381 ggatttcaaa aaaatcttca cagatggttc gtacatctat ggttcaaaac aagatggaga
     4441 aaagattcaa aaccttgttg ataccgaaaa acctttcatc tattttgcaa gtattcagga
     4501 cttacgcggt tctgagtggg caggtggaaa agcaggggat aaaaactatg aattcttagc
     4561 gattgactgg gattttatta ttattgatga agctcacgaa ggaaacgaaa cggaattagc
     4621 taataacgta aaggctaagt tgcggaaaga gcataccaag gtcttagagc tttcgggtac
     4681 accatttaac cttttcgata agtatgatga ggataatatt ttcacttggg attatactat
     4741 ggagcaagaa gctaaggaga aatggtcagt agagcatccc aatgaaccta acccatacga
     4801 aggtttaccg aaagtatcta tgttcacctt tgaaatacca aataaatttg attatttcga
     4861 tgaaaataag gcatttaact tccgagaatt ctttagggtt aaggaagatg atgaaacaaa
     4921 gttgcttcat gaaggtgacg tacgcaagtt tcttgattat attactacaa acgatgaaaa
     4981 gactaatttt cctttctcaa aaccagagtt tagagaaaac ttacggcata ctttatggct
     5041 gatgccgggg gttaaagagg caaatgcttt tgaaagagtg ctcgaaacgc accctatatt
     5101 caaagattac aatattgcaa acgtagtcaa gacaggtgac agtgagcatg ctagtgattc
     5161 agatttagaa ttggtgcgta aagctattgg taatccagct aagtctaaga cgataacctt
     5221 aacagttcgc aagcttacaa caggagttaa tgttccagag tggacagggg tatttttcct
     5281 ttcaaacaca gaaagtccta catcttatct gcaggcagcg ttccgtgcac agacaccttt
     5341 taaccatgca gagcttggaa ttaagaaaaa ctgctacatc tttgattttg cacctgaccg
     5401 tgctttaaaa attatgagtg gaagtgtcgg actaactagc aagaagggaa aggttaatag
     5461 ttcagagcaa aagaaaaaac tagagcgcat gctaaatttc ttacctatcc ttggtaaaca
     5521 ggggaatgtg atgaaagaat ttagcgttga ccgaatgctt acggcactga agaaggctta
     5581 tgcagaaaaa gctgtacgga ctggctttga agacagctct ctttacaatg acaacctatt
     5641 aaatttagac caagctgatc ttaccaaatt tgaagacctt aaaaaaattg ttggctcaag
     5701 taaaccaacc aaagtgaaag acttcattgt ttcagataac ggtatgagtg aagaggagta
     5761 tgaaaaagct tcgagggcag aaaagaaacc aaaacgtcaa cgtaccaaag aggaacagga
     5821 agcaatagat agggcaaaga ggcttcgaga gcagcgaaat aaaatgattt ccattttgag
     5881 gggcgtttct attcgcatac ctatgatgat ttatgggatg gacattgata ttaaagatga
     5941 cgttactatt gagatgtttc ttaatttggt tgatgaggct tcatggaatg agttcatgcc
     6001 agaggggtta agtaaagggc gattcagaga gtttattgag tactatgatg cagacgtttt
     6061 tgtggaggca ggacgcataa tccgtagacg tgcaaagtct tatgatgagt tagatgttat
     6121 tgaacgtact aggaaaatag gtgaattatt tagcactttt aaaaatccag acaaggaaac
     6181 cgtattgact ccatggcgag ttgttaatat gcaccttggt aacactatcg gtggactttc
     6241 cttctttgat gaagaatacc aaaattctac ggagaacggt caaccaatcg tgcgatggag
     6301 gaaaactgac tgtacagatg atatttttaa ggaaaataga aagattcttg agataaactc
     6361 aaaaacaggg ctatatcctt tatatgcagc aacgagtatg tactatgttc agctccttaa
     6421 acaaagcgat attaatgctg gaagggtaga ttcagaggca atatgggaaa aagtattatc
     6481 agagcaaatt tttgtcattt ctaaaactcc aatggctaag acgataacga agaggacttt
     6541 gattggttat aacgcatgga aggtaaatgt tgaatactca agtgaattag ttacgagtat
     6601 gaaacgttca atcaatgacg gtttaacgaa tttgaaagga gtttataaaa acgtgaaatt
     6661 tgatgtgata attggtaacc caccttatca ggagaaagat ggaggttcag gagctagtgc
     6721 tacaccgcta tataatctat ttgtagaaac ctctgttaag ttatcagaac gctatgtttc
     6781 gatgattact ccttcgaagt ggtttgcagg tggtaaaggg ttagataagt accgtgactt
     6841 tatgcttaac agctctagct tgaaggtgat ggtggatata gtaaatggga aagaaatatt
     6901 cccaaacacc agtattggtg gcggtgttag ctatttcttg tgggataaga aatataatgg
     6961 attgacacag tatactaatc aacatgatgg tgtatcaaat acacaagagc gaaaaatgaa
     7021 cgagtttcca gtgtttgtgc gatataatga agccatttct gcaattcaca aaattgggga
     7081 acacgctagt gttggtgact ttgttatatc acgtaaccca tttgggcttc caacgaaaat
     7141 tcgaggggaa gaagtgcagg attccagaaa ttcaataaaa gtaatctcta gtggtggggt
     7201 aggctttgtt ccactggaag atatcactaa aggacaggat atggttggaa agtataaagt
     7261 cattagtagc tcactgacta gcgaacatgc aggtgaaccg aacaaaaatg gtatgtttaa
     7321 ggtgatttct actaacagag ttattaaacc taatgaagta gttacagatt catacctagt
     7381 gctattttct gctgataccg aaaccgaagc aattaattat ctgaagtatt tacgaacacg
     7441 tttttacaga tttttattac ttcaagcagt gacatctatt cacctatcca aagataagtt
     7501 catgttcata ccagtacaag attttacctc aggttcagac attaactgga atgtaggtat
     7561 tgaagaagtt gatatgcagt tgttcaagaa atattctttc gatgcaagtg agatattgtt
     7621 tattgaccaa acaatcgtcc cgattcttca cgaggaatat tactaagaga acaagctaac
     7681 aaatgaggct tagaaccctg ttttcttgat taattgcccc actttaaatc aagatttaac
     7741 tgtctattat caacaggtca aggtaaaata aaggatgtta gcaagtaaag agattgattt
     7801 gagtctacat cgaacaaggg aataatccaa taaaaaatga tttagaatat caaaataaca
     7861 aaaaagagga ctacctgtat tagtcctctt ttttgaccag attttgacca gtctatttta
     7921 cattctaata tattcatatg agctaatttt atgattaaat ggtaagtttt tccttgtttg
     7981 ttttagttta aactagtgtg taattcaaaa atctatatgg aagggtctgt ggggtaatac
     8041 ttaaataaag gctaggaacc tgataacatc aaggttccta gcctttttat aataaaatga
     8101 agcgaaaata atttctttta aagagccgag attatcagct atataagagt gaatttgatg
     8161 caaaaaacag agccgaaaca gtcttggtgt tcgtagctct gcttatatgt ttcgaattta
     8221 agacaaagag ttggcaaaag atgttgataa ggaagataag ataactgtgt tatataaact
     8281 aggtaactaa ctgtaacaag ctaattttaa gagattctta ttagaagacg tttaggaata
     8341 taactaagaa aatgattata caggtaattg tcatttcaat aatgttttct aattttcgcg
     8401 tctttgtttt aagaaaaagg ccagaatcag ttggaaaaaa gttcgtacga tagtgaagag
     8461 gggcaaaatt tcctactaat attcccacta acaagagata aaacggccag gttggtgtga
     8521 ttcctctata aaaaaatgcc catgctaccg aaatcccata gattaacaac tgaacaattt
     8581 ttacaatgaa aaaattgttc tgccattact caaagtctct tcctccttgt atcgtttatt
     8641 tgtttcattt tatcattatg ataggcgctt gaacaatcca ttttgtattt tattgagtac
     8701 tcttggataa actaccagcg attatcatat ttatttatgt tactgtaagc catcatataa
     8761 aagtaaatga gcagatcata gaaatataaa aaagaactaa aattgatcta aattatgtgc
     8821 agcttgacta cgtaccaatc tatattactt actagattgg tcgttaatct attcggatcg
     8881 aatgagcaaa atatttttgt gaatgtccat ccttgattat gattccaaaa agaatcattg
     8941 ggaggctgtg gcgtaaatat tatactataa gccagaaata cctatcattc tgaacttttt
     9001 tatttaggaa ctttcatctc aaggcttttt caattaattt gtacccctgt tttttggata
     9061 agatcatgtg cattgatttt ttctatctct acgttcatct cctacttaat gcctatctgg
     9121 ctcctgaggg cttcttttta aggcgtcgtc atagtcttgg ctgaggattt cttggtaatc
     9181 tgagggaatg gcttcccaag tgagcaggcg aacgttcatg acgtgttttc ctttgtgttt
     9241 gattacagca tggtttttct ctttttctac ctctccagcg tgaaaagaca gccatgtacc
     9301 atggccaaag atatcattac atacccaacg ttcgatggaa ttgtccacgt atcctacagg
     9361 gagtgtggta tagccgattt gtggtttcaa aaaaggattg aatcgatcga tcgtttcatt
     9421 tttgtattga taattgataa gaaaaagata gaccaaacaa aagacgagca gaaagaaaga
     9481 tagtgtcttt ttgagtgaga agggttgttt tgatgaataa gatttcttgt taacaagagg
     9541 ttcatctggc aatgttggtt ctattgattc ggtagctgat tcaatagaag gaaaatcaat
     9601 cggcagacct aaagtatgat gtaaaagtga cagcatttca aagtctggca ttgtacgaga
     9661 attttcccaa ctagaaatcg ttttatcgga aacaccaatt ttttcgccta attctttttg
     9721 cgtaagctta caatttctgc ggtaagttcg tattttttct ccggtgttca tcttcttctc
     9781 ctttcgattc tacagtatat agatttattc tacatgacct atacacttga tagatacgtt
     9841 tttttgatga aaaacggtat gattttatca aagaatcatt taagtaaggg agagtggtga
     9901 taatcaaaaa aaagttcaca gttttactca caatcatagt gaccggtatc atgagtggtt
     9961 ttgccttggt tagtataaat aaacaggtac tctatcggac aaatgaattt ttccatcaaa
    10021 cagatactta tactccgatt cgattgccac aacattttat tgggcaagaa gaatatgagc
    10081 agctaatcat ggtatttgaa aatgtctcat cagaaactga gctttcttat atgaaaaaaa
    10141 cagtaaatga atccaatgaa gtagatacat cttggaactt caagatacag ccaaagcttg
    10201 aaatgacatt gtattatcaa ggggatgtca aatcttctca cgagaaggta ccctattcta
    10261 atacctcctt tcgcgtaacg tccattgaag aatcgatcaa aataaaagat tttgaaggtg
    10321 aatttttctt gatgacgaga gaaaaagaag cctatgaacg ggtcatttca ctattcactg
    10381 atcgattcaa tcaagcattt cacactgatt atgccactaa tatttttgaa gactttgaaa
    10441 atagctattc gtattcggtt atttcaaata cagacgtata taattatcga gtgtatttaa
    10501 ctattggatt gattctttta ttccttttgt tatcatcctt tttcttattg atgaataaag
    10561 aaatcagttt attgttgaat aatgactttt cattacatca agtattgtgg tgtttattgg
    10621 ggaaaaagaa aatcattatt acattcataa ttgcaggaat cattggtggt tttattttta
    10681 tgtattataa ggagcaattt ctttatttgt tccagatgta cgttttcttg ttcagcggaa
    10741 tatatggtat ctctttgatt tctcttttat tagttgaaaa aatcgcttcg ttaagagaag
    10801 cgttcaacta tatccaatac attcttttta catttggatt gttgttttct cttcttttga
    10861 ccgttgccaa tgtcgaatta gcaactatcg ttttttcttc ttcacagtta gctgtttccc
    10921 atgaaccacc aaaagaaatc gctggtgagg actatcatgt attttatcca gtaaccatcg
    10981 ggaaaaacca cgtggatttt atttattcca atcgttttgc atcagcagca gatcaggaat
    11041 tatatgaaac tttgaataaa aacggaagta tattagtcaa tgtatcagat tacttgaatg
    11101 aagaaaatga acagtttggc agagggataa aaataaatct gaattatctt aagaaatttc
    11161 ctttgattga tgtctctgga aggttgatcc aaataaccga aaaagaaacg caccctgtta
    11221 tattgatccc tgaacgatat agacatacag atttaaaaaa tgacctggcg caaataacag
    11281 aatattatca agaaatcagt gaaaaagaac cgaaatttct atttataaaa aacaatcaac
    11341 ccatttatac atttattcct tctatcccct ggatcgaaca ttatccggtt gttgaaatac
    11401 tgacattgaa aaacagtatg tatttggaaa gaaatattct cagcggagaa atctatccac
    11461 cgttaaagat caagataggc tctttgtcga aagaaaggtt atttgagctg attgaagaaa
    11521 gtcagttacg tgataacttg cagttatcat ttccgtatac tcagactgaa gagatagctg
    11581 tcaaagtgtt aagcagatca tttcattact tgatacagat atttttactc actttctttt
    11641 ctttcttctt gttgagctat gtcatgttat gcatatattt tgtctacaat tgtcggaaaa
    11701 tcgctatctt tcgttcaagt ggttattcgc tctttgaaac gtataaagat ttcttcatga
    11761 tgaacctcat caaatgggga acgacaagtg taatcttcct ttttcttata gaaagagagc
    11821 ctaaatatct ttttaatatt tttttcttta gcttcattga ttttattctt tcagttgttt
    11881 ttattttgtc tacagaaaag aaaagtcagt tattgctgat gaatggaggt taacaattgg
    11941 agccgttgat agtgataaaa ggtgcgaaaa aaatcattcg aaacaaaacg attcttcatt
    12001 tggatcgttt cactgcggat gctggggatc ttgtgactgt tgttggagaa agtggagcag
    12061 gtaaaagtac gttattgaat atattaggat tgaatgatca gttcagttca ggacaattct
    12121 atttgttcga tcaagagacg aaacaattaa ctgggagaga gaagcgcttg ataaaaagaa
    12181 ataccatatc ttttcttttt caagattttg ggttgattga atatgaaaca atcgatttta
    12241 atttagatat tggattgaag ttttcgaatt taaatgtttc agataagcga acagcaaagt
    12301 atgaggcatt gaaaaaagta aatataaaca agaagctaag tacgcctatc tacacattat
    12361 ctggtggtga gaagcaaaga atcgcctgtg cgagagtctt attgaagaat agcaaaatca
    12421 ttttagccga tgaaccgact gggtcattgg ataaaagaaa taaggataaa gtagttgaaa
    12481 tcttatcgca acaagcttcc caaggtacgt tagttatcgt agtcacgcat gatccatatc
    12541 tgaccaaaat aggaaacaag aagatcatgc tttaaaaatc aaaaaggaaa ggatgtcgtt
    12601 ttatgaaaaa agcagttatt atttgtgcac tagggatagg ttttgttgga ggaaacgcta
    12661 tgtcatctga agtggaagca aattcagttc acggtgaaat ctattacaaa tctttaaagc
    12721 caggagagat tcattttgat gctaaaggta atattattaa gtcaaattta ccagtagacc
    12781 gggaaatttc tagaacagca attaatcata gctctggaag atgggtttat tatagtgata
    12841 caacttgtac gagaaaaaca ggtcattcta accactatag tcgtgtctat aatcgtcacg
    12901 gtgcaaaagc gaaagttgga aactctattc gatcagcaaa tgcaacaaaa ggagtatggg
    12961 cctatgcaag tgcgacagga aatagaactg acacattctc atgttggtac aatccaaccg
    13021 gttggtatta agtatccaaa agtttatata aaatagaaaa aacatataat gaaacagcgt
    13081 taaaagttat ttttggtagt tttaatatat tcatttttag ttgtataaaa atatatcata
    13141 ataaaaacaa caaaaaaatg tctggaaaat cgaacataaa agtgtctgat ttgaatatcc
    13201 cagcagcgga agaagaaaaa caaaatcgat aacatttgtt ctaagaatta gttacgttaa
    13261 atacggaacg caagatagac ttgaaaaacg gtaacaaaag aagtagtata ttaaggtgtg
    13321 atgtgctact tgacatttat tctgctgagc gaactttctg gattgtgtag ccttatatct
    13381 attcaggacg tatcgagcag attagtaaag gtgttcttga tgattttcat cttgaacacc
    13441 tttgttttta gcaattcgca aaaaacgaaa agtaggagaa ttgataaatg aaaaaaagat
    13501 ttttagcact tgccatcgta ctaggcactg gcttattgtc aggctgtacg aatgccggtg
    13561 aaaaaacagc cgttagttat aaaggcggta caatcagcga acaagaagta atggatagct
    13621 tgaaaaaaat gcaaggagca gattccgctg tgcaacagtt gatcgtttat caagtatttg
    13681 aagataaata tggagatgac gtatcaacca aagaaatcga ttctcaatat gatcaaacaa
    13741 agaaacaatt gggtgattca tttgattcac aattgaaatc tgcaggttac acagaacaaa
    13801 cattcaaaga cagtatcaaa caaagtctag cctttcaaga aggtctaaag aaacatatca
    13861 aattgaccga tgaagattta aaaacggctt gggaatcttt ccatccagaa gtggaagctc
    13921 aaattatcca agtagcaagt gaagatgatg caaaagatgt gaagaaagct gctgataagg
    13981 gagacgattt ctctaaatta gccaaagaca agtcaactga tactacgaca aaagaagatg
    14041 gcggaaaagt gaaatttgat tccactacta caacggttcc ggcagaagtc aaagaagcag
    14101 cctttaagtt gaaagatggt caagtttctg atgtgatcac ttctaccaat gcttcaactt
    14161 atactacgga atattatgtg gttaaaatgg tgaaaaacca aaacaaaggc aacgacatgg
    14221 ataaatacaa aaaagaattg aaagaaattg caacagacac aaaattaagt gacagtacct
    14281 tccagaataa agtaattggc gaagtattga aagacgctaa tgtaaaaatc aaagacaaag
    14341 actttgaaaa tgttttgagt acattcactt cagattctag tacagcaagt agtaaataag
    14401 cggtataaat aaaaaatatg aactatttaa atcaataaaa ctgttcatct aaatcttttt
    14461 attagaacta aatcaacagt agtttaatta ctacttgatt tagttctttt tattttaaaa
    14521 atttttttta cttagaatcc agcgacccta gatatttttc tgtataatct taaataaaga
    14581 aaacaatatc aaaaaatgca cgtagaagta gataaatgga gtggttttgc aaatttcttt
    14641 tatttctaga agttattcac gtatacggat ttgtttttct cacaaataaa aaggcaggaa
    14701 gtacaatgga tcatttgtat ataaaatata ttcatcaatt ttccgttttg gtgttaggca
    14761 cactaattat agcggggatt gtcgcattta ttattcaagg ccgtgacata ttaacagtac
    14821 atcaagagtt tttcagttat gcatttggta ttcctctgat cgctataagg tctgataaca
    14881 aaaagtggaa gaaacgctat tacattctct tgctattttt gtgtttttat ctgccaccta
    14941 agatttttac tttattaggt atacaatgcc tatcattttc ttttatttcc tatatcattg
    15001 ttttaatttt cctcagtttc atagtatgga tgttttatct tgtcaaaaaa taaatgaatg
    15061 tttcatgaac agtacttcat cacagcctaa tttttttctt tatgctatcg ttatattaaa
    15121 gaaatcaatc agaagggaaa gaaagtgatg aaaaaagttt tattagtggt aaaccccagt
    15181 tcaggcggtg aacaagcaaa ggaatttgag caattagcga tagcaaaatt ggaatcggtg
    15241 tttgatgaag tggtcgtctt gcatacaaaa aaagcagggg atgcaaaaaa ctttactcgc
    15301 gaagcggcta cggaagggta tcatagtgtg tttgtcatgg gcggagatgg aacagtcaac
    15361 gaaggaatca gtggaatcgc tgaacaagaa catcggccaa atttcggatt tttcccattg
    15421 ggtacggtga atgacttggc tcgagcatta gggataccgc tagaacctga ggaagcgatc
    15481 aatcattttt cgattgaatc agtcaagcca ttggatattg gaaaaataaa tgacgactat
    15541 tttatgaatg tcgtcgcaat tggctctatc cctgaatcaa tcaatgatgt agatgcggag
    15601 aagaagacga aatttggaaa actagcttat ttcatgtcag gaatcaaaca gttagcttcc
    15661 acacaatcct actcgtttca cgtagaagtt gatggaaaga aggaagaaat tgagagcagt
    15721 accttgctga taggactaac taactcagtc ggcggttttg aaacattact tccaaatgca
    15781 aaagtggatg atggtaagct ccatttggtt tatttaaaag attcttcttt gatcgatacg
    15841 cttaaaacat tgccagacct attaaaagga gtagatgaat ctacgaaaaa tctagcctac
    15901 cttacttgtg agcaattagt tgtgtcatta gctgatgagg aagaattgac gacgaatgtt
    15961 gatggagatg aaggggataa attacctgtg acaatcaaag tattgccctc acatttacag
    16021 gtttattgtt aaaatggagg ttgtgaccga ggagttggcg ggagaacacc gcttgttcgg
    16081 gataagggac tgtgacaaga cttttgtcac agcctttttt ttgtacaaaa aagaaattta
    16141 cacctaatag aaaaattttt ccataaaaat acatatttta aatatgaaag tacaattgga
    16201 aatagattaa aacgataaaa taaaattgtc aaaacgtcag agaggatggt ggagaatgaa
    16261 tcaatgtgta aaaaagctga ttgcgtcgat tttgtttgtc ttccctctct tgatggtgac
    16321 atccgttttt gccgatgtag agaaaacaaa cgaatcaacg caatcagaga atcaaagttt
    16381 tgacaagact actttttcag aagaatcgat tacttctgaa actacagaat ctcaaagtga
    16441 ggcttctact aataaaaggc aagaagaaaa taagacaagt gagacctcag aagtagctga
    16501 acaaacgtct gatagcagtg aagcggcact ggcaagagct gtttcagcgg atgggtacag
    16561 cgaagctgcc acaacagaag aactggcgca gcttctcgca gacgaatcag taactaagat
    16621 ccgactgatt cagcctttga ctttagacag ggaattagag atcaaacgag atatcgttat
    16681 tgattttggt ggattcgctc acaatttcgg cacacaccat atttatatca atgagatacc
    16741 tcagtcgatc gagttccaga attttaaagg aacagctgca catccaggtg gattgacacc
    16801 aaatatcgat ggaaatgcca ttatcattgc ttatatgacc gatttttggg gaagcagata
    16861 tcattttacg ggagaaataa aatttaccgg gacacttgat ttgtatgatg ggtccaaatt
    16921 aggactgatt tacgctcctc gtgcaactgt cacattagat ggtgtttccg gtgtgttgga
    16981 tgtccaacca gtgaaggaag gactgaatgc cgctccgggt aaagcctatt tttgtagaag
    17041 ctatcaattg aatgtgatca atggtagtca actttatgga ccgtatctag ggaaattcta
    17101 cggttttcta gattcaggag atgagactgg tagtggaaaa acagcgccag gaatccatat
    17161 cttaagcggt tcaaaggtct ctcttgatta tgatcgggca gatggcgtta gcgatgaagg
    17221 agaggcagtc gatacgctac ctggtaatgt catgtttgaa gtcagtggtt cgggaagcga
    17281 attttcggta aatacaaaga tcaatattac caatgacaac aatcgcggaa tcatccaaat
    17341 gagaggttca ggatcgaaag tcactgtatc gaatggtggg aaaatcacca tcaatacagc
    17401 aactacgggc ggatttcgct tgcaaggaga ttctagtcaa atccatgtat caagtggtgg
    17461 acaaatctcg gtcaaaatgg ctggagatga cgatcaaccc gggaacaatg ggatgcgttt
    17521 tgtaggaaaa ggcctttctt tgatcgtaga aggagccgga tcagttatcg acatcgataa
    17581 gcagagtggg cgttccagcg cagttcgttt tgagaatggt acgcaaaagc tgacagtaac
    17641 caatggaggc tcattgaggg taagaaatac aggtgatggc aaatcttacg tgaacagact
    17701 caatcaagga aatcaagcga tccaatttta tgacgcttct ggttttctag aaagtccagg
    17761 ttcagctgat tttacagtca ctggagaaaa atcaaatatc gatatacgcg cagattccgg
    17821 agcaactgta gatacaactg gagatattga tttaaatttt acggcaggtg aaaaaactta
    17881 tttagtcatg gtcgggaaaa caggggaaga taagaccggc atcatcagtg gggatgtgtt
    17941 gaatgtggac ttagaatctc ctacctattt tgatttccaa aacaaacgga ttggaagcga
    18001 gaccaatggc ataggcggct gggtattcca aggaaatgga gattcttctt taaagatcgc
    18061 ccattcagaa atcgctttat ggcgaaaaac aggcgcaaca ttcgataact ttgaaaaaga
    18121 cccggattat ttttctgata tgacagactt atcgatcaat gggaccgact taggcaattt
    18181 cgtatcaagc cctagtgcag gtttaacaaa tgaatttgct cagacaggtg ccggaatgaa
    18241 aaattataat cgaatcagtg ccaataatca gctcccgatg attgaatcct taagagtgcc
    18301 aacgaatgca gataaaaaaa tctatgggca tgtcgttgtt cccgaaggtg tcgaggcaaa
    18361 gccaagagat gcttggacag gcgaagtaga agtgacttta cgtattactt acgcagatac
    18421 gacgaaatca tctgtagaaa ttactgctct cacgcaagga caaacagatg aaaatgaagg
    18481 ggcaggatat aacccatggg gagaaggcga acaaggcggc ttgttcgaag ttcaagtacc
    18541 caatgatgag agattaaaaa cggaggatca agtgcaagtt gttgctgcta aaaaagtaag
    18601 aggtggccaa gaagtgacag aactggactc tgccaaaacg acagtcgatg tgattcctcc
    18661 tgaacctgct aatttaagta ccacattgat caatgcagct tctcgcacga tcacaggtac
    18721 aggtgaagca ggagccttgg tttcattgaa aaaaaatcaa gctgttttgt cagaaacaac
    18781 tattgatgat acaggggaat ttgttctttc tatcccagaa aatcaacttt ttgcaggaga
    18841 tgtattagaa attgtattaa acgaccaagc aggagaagct actgctaagg gtgtgcagaa
    18901 caagccaagt accaacgatg aaattgggaa tcacaatcca agtgatacgc cagttgttta
    18961 tcatgatgcc ccgccttttg cacctgctac gaagatcgta gtagaaggtg gtctctcatt
    19021 tcttgcccct tccaaactcg attttggtca gatcaaagca actggtttga cacaagaagc
    19081 atttggccaa atggatatac aggaaaaatt atggatttat gatcagcgag aaacgaaaaa
    19141 tccgtggatc ttaacgataa aattatctca gcctttcaca aatgatgcag gattttctat
    19201 gcaggatgtc ctatatttca agaaaggaga ggagtatcaa ttagtgaatg aagaagaact
    19261 ggaaattgtc agaggacaaa attcaacgaa tgtgcaagca gattattcag aatatttaaa
    19321 taacggtcgg gcgtttaaac ttgtcttaac caaagaaaat cagatagctg gtaattactc
    19381 agcagagata acatggacat tagcagatgc gccgacagaa taaagatcaa ggaggatgat
    19441 tgatgaatcg aatatggaat aaaagtcatc gaaacaactg ctctttactt atgatccttc
    19501 tccttggatt catcctttgg cagacacctg tccatgcctc cgaattcaat tttgcggtag
    19561 attttgaatt accggctaat cagattgata agaacaaaac atatataaat gtaaggatgg
    19621 agcctgggaa aacacaggaa atcccctaca cggtctttaa ccgaacagat aaatcagtaa
    19681 cagttgagac attgatccac tccgctacga cgaattcaaa cggtgtgatc gaatatggag
    19741 aatcaaaaag taaatttgat gaaacattaa gttatgatat gaaaaactta gcaaaaacag
    19801 tgggagaaat aactgttcct cctcaaagtg cggtcactga gacactttca ctgaaagcgc
    19861 cagaaaaaga gctggctggt gtggtcgcag gagggatcac gtttcaagaa aaaaaagaga
    19921 acgtttctaa caaaagtaca gttggtgtcg tcaatcagtt ttctcaagtg aaagcaatct
    19981 tgatttgaaa tagcgaaaaa gagtcttccc cagatttgaa attaaaaaaa gcttatgcgg
    20041 atcaaagcga tggaagaaat gtgattaagg cgaatcttca aaatccaaat gcttcttata
    20101 tgttcggctt gactacatcg gttgaaatct acaaaaaaga aacaaaagag ccttaccttt
    20161 caataaaaaa agaaaaaata gatgtagcac ccaatacaaa ttttgattta cttgtcccat
    20221 tagaaggaaa aaaattagct ccgggacatt atcaagcggt tgtgaagggt gcttggaaag
    20281 aaaaacgctg gaatctccat accgattttg aaataactga tgatgcagcg gaccaattga
    20341 atgaaaagga tattgattta aaaaatcagc cagaaacatt tgactggcga tggctgatac
    20401 ttgttggagt cattcttatt ggcttatttg ctggattatt tattttaaaa gaaagaagga
    20461 aaaagaaatg aaaaaaacaa ttgcattaag taccgttcta gctggaagtc tattattatg
    20521 tacacaaagt gtttttgctg agaataagag ctcagccact acagaaggaa cgatttctgt
    20581 gaccaaacca gatgctgcaa atcctgaaga cgttgttcca gttcctcctg ttgatccaaa
    20641 tgatcctgat actcctttta cacctgacga accaaatcag ggaacatccg gattactgac
    20701 gattgaccaa gctccagatc ttgattttgg aacaatcaag ttaggtacag caaaaacagt
    20761 atatgctgca ttacaaagcg gaacggacag tactggagca caaacacaag tacagaattt
    20821 cgtacaagta acggataaaa gcggaaatta tgccggttgg aaattatcag tcaaacgaac
    20881 agaatttatt ggtacaacat ctgatacgaa taaactaact ggttcaaagg tgaaattcaa
    20941 aaacgccgtg attcgaaata gcgcaactaa tagcagtgga atgccatcta ccgtttctgg
    21001 aactggcgct gaaggaatcg aaatcccagc agatcaggca gtagatctag taactgcagg
    21061 agcaaatgaa gggattggca catggattta ttcattagga gagaatgtgg aacaagggag
    21121 acaatcagtg gaattatttg ttcctgtatc caattatgct gtagacaact acgtttcaac
    21181 attcacatgg tcgttaacag atgctcctac agaagaggaa gcgtaaaatc atatcaacga
    21241 cttcagggag tggagccgat tcaaggccca ctccctgaaa tctgctatgc ttacgtctca
    21301 gctcttattc atcaactcga agcagttttt tggaagtcat ggaaacgttc ctttgtcttt
    21361 tcaaagatct ttcgaccaac gagtaaggag tcaccgttga aaaattctaa cacataatga
    21421 gcagaatcaa ttttctgcaa ttgcgataag ttgatacagt aagattttaa aagtaaaaag
    21481 taagcatact tttctaactc tgtcttcaat tgttttaaag aagtattcac taatttatct
    21541 tctgtagttg ttttgaccat aacttggttt ttcaaacctt tgatactttc aatatataaa
    21601 atttcccgag gatacaggac gagac
//
LOCUS       DAXLPC010000046        20982 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.046, whole genome shotgun sequence.
ACCESSION   DAXLPC010000046 DAXLPC010000000
VERSION     DAXLPC010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20982
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.046"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(565..1590)
                     /locus_tag="ACF3UE_001618"
     CDS             complement(565..1590)
                     /locus_tag="ACF3UE_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3635023.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            1865..3550
                     /locus_tag="ACF3UE_001619"
     CDS             1865..3550
                     /locus_tag="ACF3UE_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFD3635024.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            3564..4847
                     /locus_tag="ACF3UE_001620"
     CDS             3564..4847
                     /locus_tag="ACF3UE_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3635025.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            4917..5786
                     /locus_tag="ACF3UE_001621"
     CDS             4917..5786
                     /locus_tag="ACF3UE_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3635026.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            5783..6619
                     /locus_tag="ACF3UE_001622"
     CDS             5783..6619
                     /locus_tag="ACF3UE_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3635027.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KVRSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            6645..7712
                     /locus_tag="ACF3UE_001623"
     CDS             6645..7712
                     /locus_tag="ACF3UE_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFD3635028.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            7709..8536
                     /locus_tag="ACF3UE_001624"
     CDS             7709..8536
                     /locus_tag="ACF3UE_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFD3635029.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            8581..9606
                     /locus_tag="ACF3UE_001625"
     CDS             8581..9606
                     /locus_tag="ACF3UE_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3635030.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            9603..11786
                     /locus_tag="ACF3UE_001626"
     CDS             9603..11786
                     /locus_tag="ACF3UE_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFD3635031.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            11786..12916
                     /locus_tag="ACF3UE_001627"
     CDS             11786..12916
                     /locus_tag="ACF3UE_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFD3635032.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            12913..13590
                     /gene="pgmB"
                     /locus_tag="ACF3UE_001628"
     CDS             12913..13590
                     /gene="pgmB"
                     /locus_tag="ACF3UE_001628"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFD3635033.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            13674..14201
                     /gene="msrA"
                     /locus_tag="ACF3UE_001629"
     CDS             13674..14201
                     /gene="msrA"
                     /locus_tag="ACF3UE_001629"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFD3635034.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(14402..15088)
                     /locus_tag="ACF3UE_001630"
     CDS             complement(14402..15088)
                     /locus_tag="ACF3UE_001630"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFD3635035.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            15168..16706
                     /locus_tag="ACF3UE_001631"
     CDS             15168..16706
                     /locus_tag="ACF3UE_001631"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFD3635036.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            16826..17293
                     /locus_tag="ACF3UE_001632"
     CDS             16826..17293
                     /locus_tag="ACF3UE_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFD3635037.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            17827..18255
                     /gene="rplM"
                     /locus_tag="ACF3UE_001633"
     CDS             17827..18255
                     /gene="rplM"
                     /locus_tag="ACF3UE_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFD3635038.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            18271..18663
                     /gene="rpsI"
                     /locus_tag="ACF3UE_001634"
     CDS             18271..18663
                     /gene="rpsI"
                     /locus_tag="ACF3UE_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFD3635039.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(18751..19977)
                     /locus_tag="ACF3UE_001635"
     CDS             complement(18751..19977)
                     /locus_tag="ACF3UE_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3635040.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(20049..20351)
                     /locus_tag="ACF3UE_001636"
     CDS             complement(20049..20351)
                     /locus_tag="ACF3UE_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003013637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635041.1"
                     /translation="MTIAANNDTSVRLAVNWGEVKFLCAYPKQFKNFITTILGDDFIE
                     SRVYLNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKDFMNTFKIT"
     gene            20899..>20982
                     /locus_tag="ACF3UE_001637"
     CDS             20899..>20982
                     /locus_tag="ACF3UE_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFD3635042.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGA"
BASE COUNT         6783 a         3753 c         4353 g         6093 t
ORIGIN      
        1 ttgtcacaac ctcttttttg gtttgtctaa aataatttgt ctaactagaa gaaaagtggg
       61 aaaggatctt aacaacatcg gttcgtatcc aattaaggta tcggaacgat catcttccaa
      121 gagaagtcaa tcaacaaaag taaagataga tcattttttg aatgcaaaat aaattgatgg
      181 gaagatagag cggttatttt taatattttg ctagctatta ttgaataatt cctcgaataa
      241 aacaaaacca gtagacatgt ctgttattct atttatgttt tagagataag tatccccaaa
      301 taacatggat tgaaataagg gtaaatgtgt ttaaaaaaac gaactataaa aacttataca
      361 caacgtggtt aaaaatagtt ttttcttccc tgtggaaaaa atagtttaac acaaacatta
      421 tagttatcca cagctatcta aaacagatgg aaaataagaa aaattcgcta aaataccggg
      481 agggggtaac gagggatgag tgattgaaaa aagaacagag taactgactt atcctcagtg
      541 tttctgttct tttataattc tgttctacat ttcttgttgt tggatcgaat ctgtgagagt
      601 aatctcggtt gaaagaatga ttcttttttc ttcagggtat tggtggtgga ttagttggaa
      661 taaaagttct gtggctttga ttcctaactg atttgtcgga atgtctatcc gagtcaactg
      721 tggcgaaaat agggaggaca ataagggatc actgaatcct gcgatcgaaa gatcatcagg
      781 tatctgcttt ccagattgtt ctgccacttt gtaaatactc aatgatttta atgcatcggt
      841 agaaaaaatc gcagttggtc tttctcgtag cttcattaaa tcattcattg ctgccatgct
      901 atcttctaag cgaaagccgc cgtctataat ccattcatta cggatatcta ggtggtgatc
      961 aaataagcat tgacggtaac cattgagacg atcattggat acataaactt ctgtcggagc
     1021 atggagacag ccgatatgac ggtgtccatt cttgatcagt gtttccacca aatcgtaact
     1081 atcctggaaa ttatccgtgt ccactgagta gatgttcgtg tagtcgtttc cgacttttcc
     1141 gattaccaca ataggaatat tgtattgatc caattcaaaa agaagtgttt catccatcgt
     1201 agagcttaaa ataataattc ctcggatcat tttttcttgg atctttttcg cgcatttttc
     1261 tagctcttct tctggtgttt ttgccgtttg tagaatcaag tcgaagttat tttgttcaga
     1321 aacggcagaa atggattgaa taacatctga aaaaaaagga ttgccatagg tcgtatgaga
     1381 agtacgatga gataatgcta gaatcgcgtc aaaaccattt cctgacagtc ctcttgcaat
     1441 tttgctcggt tcataattca attctttgat tgcttgaagt acacttgctt ttgctttatc
     1501 agagatattt ggctggttat ttaatactct ggagacagtt gattttgaga cattagcttt
     1561 tttcgcaatg tcataaatag taggtttcaa ttttatatgc acctcctttt tgggagcgtt
     1621 ttagaataat tccatagtac aatagacatt cttttttgtc tatgattttg aaaatttagg
     1681 aatagcttgc atgatcatga gagaccatat ttttttaaga agctattaat tattgataca
     1741 taagctttct tatttgtatt tttgtgtata tcaaaattat ttaaaaaaat gctattgaca
     1801 gtaagcgttt tccataatat gatcaaatcg ttgggaacgc tcccaaaaaa gaaaggggaa
     1861 tccgatgtat acaaaacttt tacaagcgat ttatcgcgac tcagatttgt ctgagaaaac
     1921 cgcctctatg attgaacaaa aagtcagtgt ttatcagcag aagaaaggcc aggcaggcaa
     1981 actgcattgg gacgaagaag atattttctt gattacttat ggggatcaat tttttgaaga
     2041 gcagcaacca actttgcgta catttaagaa attttatcaa aagtatttgg cagatacatt
     2101 tagagttgta catttcttgc catttttccc atatacatct gatgatggtt tctccgttgt
     2161 aaattatcag gcaatcaacg accgtttggg cacatgggaa gatatagaag aaatgagaag
     2221 cgaaacacgg ttaatgttcg actttgtctg caatcatatg tctgccgaaa gtacttggtt
     2281 tcaggaatat ttaaacttga atgatacgta caaagatttt tttattgatt tgccactgga
     2341 tacagataca agcagcgtga ctagaccaag gaccagcccg ttacttacaa cgttcattga
     2401 caaaaacggg aaagaaaaac acgtatggac gacttttagc gaagatcaag tagacttgaa
     2461 ttttaaaaat ccagaagttt tattgaaaat gatcgatatt cttttgtttt acttagaaaa
     2521 aggcgcttca tttattcgct tggacgctgt gggattttta tggaaagaac taggaacttc
     2581 ttgtatacac ctgccagaaa cgcataaaat catccaatta ttccgtgcaa tcgctgatga
     2641 agcagctcca ggaacggtat tgatcactga gacaaatgtg ccacacaaag ataatatcag
     2701 ttattttggg aatggcgaga atgaagcaca gatggtctat cagttttcgc taccaccttt
     2761 gacccttcaa gcgattcgtt cgggtaatac aagtaagttg aaagaatggt taaaaaccat
     2821 cgatttcgca tcgaaaaaaa caactttttt taatttttta gcctcccatg acggtatcgg
     2881 attgaatccg gtacgaggta ttctgccgga aaaaacgatc cttgaattag tggaacagct
     2941 gaagaaagag ggtgcccgag taaactacaa gaaaaaccca gatggaacga ccagtccata
     3001 tgagataaac gctacgtatc tagatgcgtt aagttctcca acagatacga cggaatggag
     3061 aagcaaacgc tttttagctg ctcattcatt tttggtaacg ttaccaggcg tgccggcaat
     3121 ttatattcaa agtgtgctgg gaagtcgaaa tgattacaaa ggcgtagaaa aaacaggaga
     3181 gaatcgaaaa atcaatcggc aaaaattttt gttagcagat attgagaaag agttgcagac
     3241 agatccatta agaacagcag tatatggtga attgacccag atgctatcta ttcgaaaaaa
     3301 agaaaaagcc ttccatccga atagtttgat ttacttactg gactcagcag attcttttat
     3361 cagttttatt cgcgaagcga aggaagagaa agtcttagtt atccataatt tttccaatca
     3421 atcagcaggt tatcttttac caaaaggaga ttacctagac ctgttttctg gacaaattat
     3481 ccattgcagt caagaacgaa agttgatatt ccagccgtat gaatatatgt ggctgaaaat
     3541 aataaaataa gaggtggaaa aaaatgaaaa aaattattgt tactacctgt ctgctagcta
     3601 ctggatttct tcttactgct tgtggtgaaa gtcaaagctc taacgaatca caacagacaa
     3661 cgattcaatt catgcactct tctgtcgaac aggaacgatt aagtgtgatc aatgaactgg
     3721 ttgctgattt tgaaaaagaa aatccagaca tcaaaatcaa gcaagtgccg gtagaagaat
     3781 cagcgttcaa tacaaaaatc gttacgttag ctcgttccgg taaattacca gaagtaatgg
     3841 aagtcagtca ggattttgct aaagtgatgg ataaagatga actgattgat cagacggcag
     3901 tccaaaacgt tatcgaggaa gctggagaag ataattatta tgacggagcc aaaaaccttg
     3961 ttcgttcaga agatggaaaa agctatattg ctgcaccaat tagcggctgg gttcaaggta
     4021 tttggtatga caaagaaaaa ttatcagaag ctggtttttc agaaccagaa aattgggatg
     4081 atattttaaa aattgctcaa catttcacag ataaagagaa taaacaatat ggaattgcta
     4141 tgcctactgc tgaaggaaca atgagtgagc aagcgttctc tcaatttgct ttgtcaaatg
     4201 gagcaaatgt tttggatgat gaaggcgagg taacgatcga tacggaaaag atgagagaag
     4261 cattgtcgtt ttatcaaaac ttatcccaat acacgatgcc aggctctaat gatgtgacag
     4321 aaatcaaaga tgctttcatg aatggaacag caccaatggc aatctattca acttacattt
     4381 tgccttctgt ttatgaagcg gggaactcag aaaatatcgg ttttgctatc ccaacacaaa
     4441 aagatcaagc tgtctatggc acagtatctg gattgacgat ttcttctggt ctagacgaga
     4501 aacaaaaaga ggctgctgaa gcattcacag ctttcttatc tcaaccgaaa aacatggaaa
     4561 agtgggtctt gatgtctcct ggtggtgctc aaccagtgaa taaacaagta gtcgaactgg
     4621 atggttacaa agaaaatgaa gtcatcaagt cttttggcga gctgccatct gagattgcta
     4681 gtgcttttga tgaagtacaa gtctttggac tagtcgggga aaagaatttc acgaaaatgg
     4741 gagatatcac aagctcaggt gtgatcggaa aagcagtgaa ccaagtaact gtcggaaacg
     4801 aagatgtcga tcaagcttta gctgacgcac aaaaaaatac gaaataacaa gaagttctgc
     4861 caatggtgtt cgaaaaaagt agatagctat tggcagatta tcagggggag gtttcaatga
     4921 atcgtccaag gaaacattct gacttaaaat tagccatggg acttttagca ccaagcatgc
     4981 ttttattagc tgttttagtg ctgattccaa tgctttccaa tattcagatc agttttttcg
     5041 atatgccgct gaatcctaac tcagacgccg tttttatcgg attaagcaat tatcttgaaa
     5101 ttttaagtga tagtgaattt tatcgttctt taggtttaac agttgcttac acattcttag
     5161 ttgtagcagg cagtacagct ttaggattag ccgtagctat tttgcttaac cgcaagttca
     5221 gatttaggaa aacggtgcgt tcactgattt tattaagtta tgttacgcca tctatttctt
     5281 tgatttttgc ttggaaatat atgttcaata atagttatgg aatcgtcaat gatctgttag
     5341 tagataggtt gcagcttttc aacgaagcac cgctgtggtt cgaccagcca gttgctagct
     5401 tctttatggt cgttttgttt gctatctgga gatactatcc gtatgcgttt atttcatttt
     5461 tggctatttt gcaaacagtc gacaaaacgc tttatgaagc agctgaaatg gacggtgcaa
     5521 atgcttggca gaagttcaag atcgtgacac tgccggcaat caaaccagta ctagcaactg
     5581 tgattgtttt acgatctatc tggatgttct atatgtttac agatgtctat ctactgacga
     5641 ataaagtcaa tatcttaggc gtttatttgt atcagacagc ctttgcgttc aatgatcttg
     5701 gaaaagcagc agctatatcg attctattgt tcatcattat tgcagcggtc gtcttgctct
     5761 cacgaaagaa ggtggacttg aaatgaaaaa taaaaagagc aggaaaatct tattttacgc
     5821 gacgattttg ttgctattag ctgtcaattt gtttccattt ttgatcatgc tgatgacatc
     5881 attcaaggat tcacaagaag caattgcaac gacacaaact atttttccga aagaatggac
     5941 ttttgaacat tatcaggata ttttcaatgc tgagattttt ccattcatca tgtatttcaa
     6001 aaatagttta gtgatctcct tgatagcctc cgtaactgca gtagtgattg ggatcagcgg
     6061 ggcatacgct ttgtcaaaac tacgcttcaa agttcgctcg aaaatcaatg ctagctttta
     6121 caccgtttat atgttttccg gtattttgat cgttgttcca ttatttaaaa tcatttccgg
     6181 tctaggtttg tatgatacca atacagcact gattatcacg atggtcgttc aaacacttcc
     6241 tactgcgata ttcatgctaa aaagttattt tgacacgatt ccgactgata ttgaagaagc
     6301 agcaatgatc gatggtctta gccggatcca gatcattatt cggatcatta taccattggc
     6361 tatttctgga atcatttctg tcttcgttta ttgctttatg gtttcgtgga atgattattt
     6421 atttgcttcg attttcctgt cgacctccga aaaatttact ttaccaatcg gtttgaacac
     6481 attattcagt acaccagact acatttgggg acgaatgatg gccgcttcat tggtgaccgc
     6541 tttaccagtc atcattatgt atgcgttatc tgaacgattt attaaaggtg atttagtcga
     6601 aggcggcgta aaaggataaa aagaaaagaa agaggaaaga aaagatgaaa aaattagttg
     6661 cattagaacc aagaatagcc ggattcaaag attacgaaga ccgtgagatc gaaaagaacg
     6721 aagtacgtat ccgagtaatt ttcgctactc caaaaccagg aacagaaatt gtcgacttta
     6781 gaggattaag tccatttatc gatgaagaat tttcagaaga atggcgccta ttcttgccaa
     6841 gagaagaagg aagccaacgc ggtgtggtat ttggcgaatt tcaattagga aatatgattg
     6901 tcggtacgat cgaagaaacg ggcagtttgg tgacagagta tcaaaaagga gagttagtct
     6961 gcacttatgg acccattcgt gaaacgctga ttacaaacgg tgttgataat tataaactac
     7021 gtaaacttga tcggttggat caatggaaaa atgcagtatg ttacgatcct gctcaattcg
     7081 ctttaggtgg tatccgggaa gcacatgttc gagcaggtga tgctgtagca atcttcggtt
     7141 taggcgctat cgggcaaatt gcgattcaat tagctaaaaa agcaggtgct actaccatcg
     7201 ttgggatcga tcccatagcg cagcgtagag aattagcaga aaaatacggt gccgattaca
     7261 cgctagatcc tatgaaagca gatgtcggtt ttcgtctaaa ggaattgaca gataaacgtg
     7321 gagtagattc agttattgaa acgagtggca gtgctgccgc attacaagct tctttaagag
     7381 ggatcggcta tggcgggatc atttcttatg ttgcctttgc taaacctttt ccagctgggt
     7441 ttaatcttgg tcgcgaagca catttcaata atgcaaaaat cgtctttgct cgagcatcta
     7501 gtgaaccaaa cccagattac ccaagatgga accgtaaacg aatcgaggac acatgttggg
     7561 aattattgat gaacggttac ttggattgtg aagaaatcat tgatccagtt gtgccatttg
     7621 cagaaagcgc agaagcttac atgcgttatg tagaccagca cccagaagaa agtatcaaaa
     7681 tgggcgttca agtccgagga ggagaacaat gaaattcggt acgcaagatc aagcattttt
     7741 cccaagagac attttagaaa aatttagatt tatcaaagac tgtggatttg aagaatacga
     7801 aatcgacggt aagttgttaa tagaaaatat cgacacagtc aaacaggcaa tcaaagaaac
     7861 agggatccca gtagtgacag cttgtaacgg ctacgatggg tggatcggtg actttatcga
     7921 agaacggcgt cttaatggtg tacgtcaaat tgctgagatt ttgcgtgcac taagcgaggt
     7981 tggaggcaaa ggaatcgtta tcccagcagc ttggggaatg ttcacttatc gattaccgcc
     8041 gatggtttca ccccgaagca aagaaggaga ctataaagca gtcagcgaat cacttcgtta
     8101 tttagataaa gtagccgaag aaacaggtac ggttatttat ttggagcctt tgaaccgata
     8161 ccaagaccat atgatcaatt tgttagcgga tgcgcgtcat tacattgact ctaatcaatt
     8221 gaaacatgtg cagatcatcg ctgattttta tcatatgaat attgaagaag atgatatttc
     8281 aaaagcattg actacgcaaa aagagtatgt gggtcatatc catttagcag ataatcatcg
     8341 ctaccaacca ggatctggcg caattgattt tactcgccat tttcaaacgc tacttcaaaa
     8401 tgagtatgaa ggttatatgg tatatgaatg tcgtttgcga ggagaaaatg aagtgaaaat
     8461 ttatcaggaa tcattgcaat acttgaaaaa ctgtctggaa acagcgcgtc atttaaatga
     8521 tttagagaaa gaatagagaa agaataacaa taagtaaata agcaaaggag ggagaaataa
     8581 atgaagaaag tagcaatcat aggcgctgga caagtagcag aaaaagtaca tgctgcttat
     8641 tatcaaaaaa gatcagatgt cttagaattg gccgctgtgg ttgatccagt cagccagcga
     8701 gcagaagact tttgccgacg tacaggattt tctcatgcgt atacatcagt tacacaaatg
     8761 ctgaatgaga tttctcccga tatcgtgagt gtctgtacac ccaatcgctt tcacttcgaa
     8821 catgtattgg ctgccctcga agctaatgct tcagtgatgt gcgagaaacc accagctatg
     8881 acagctgatc aagcaagaaa gatggcagag acagccgata aaaacgggca gattttggct
     8941 tatggattcc agcatcgttt ttctgacgaa gcaacaatga tcaagaatca tcttgatgtt
     9001 ctcggggata tttattacgt agaagcgaat gcgcttcgtc ggtctggtgt tccaggctgg
     9061 ggaacgttta tcgacaaaga acttcaagga ggcgggcctt tgatcgatta tggcattcac
     9121 atgcttgata cagcgatgta tattactgga tttcctaaag taaaaagcgt tcgggcgtac
     9181 agcttccaaa aaattggtac gaaaaaaaat tcagggaaat tcgggaaatg ggatccaagc
     9241 aaattcacag tagaagatgc aatttttggc acactggaat tagaaaacgg caagatcatc
     9301 caactgaata cttcgtttgc tttgaatatc agagaagaca aactgaatgt ggctttttgt
     9361 ggcgatcagg caggtgctaa tctgtatcca ggcgaactat tcgaagatgt agatggaaag
     9421 ctggtttcct tacaaaagac cacgccagtt aatgacccac atgaactaag tatggctcat
     9481 tttgtgaatc gggcgctcgg tgaccagact cagatgattg cagatggctg gcaaggatat
     9541 gtcatccaga atctggtgga aaatttatat cgttcggcag aaacaggaga agttattacc
     9601 ttatgaaagt agaagaaaaa cagtttgatt tagagtatat caataagtat gcgagtcaga
     9661 tgaccattgg aaatggattt tttggtatca gaggaagcca ggaggaagac tatcggaatc
     9721 aagtaagggg aatgtttgca gctggtgtat ataaccgacc tttaggagca gaatcagccg
     9781 agttagtgaa tctcccagat gtcatcagat gggaaataaa aatcgacggt gaacattttt
     9841 ctcttgagac gatgaaagtt cttgcatacg agcgggcact agatttagaa atgggagagc
     9901 ttaaacgcta tgcgctcatt gaaactgctc aaggaaaaaa agtggaagtc attacttgtc
     9961 gtgttgctga tcaaaataat ctccatcagg cagccctgaa agtggtcatc aagccgttga
    10021 ccgaagactg ccaagtagat gtgaaaacgg gtatcgatgg acagcaaacc aattttggta
    10081 cacagcagtt ggttgaaaaa gaactgcgag tatttggtga cgatttgatc agtgcatcct
    10141 accagacaac agaaagtaaa attgatattg ggattgcagc taaattcaat aaagcaggtg
    10201 tattccaagc aaaaaatcgc cggatcaccg cttccttttc agaaaagatc agaaaaaata
    10261 cgtcctttac gctggagaag atcatcgtgc tctctacctc tcttcagcaa acagacccgt
    10321 ttaagaaaag tattgcccaa gcccagaaaa gcgttagtta tacagaaatt ttagagcagt
    10381 cgatgtctta ttggacagat ttttggcatc agcatcggat aacgatccaa ggcgattctt
    10441 ctttcgatca gttagcgatg gacttcgctg cttaccattt acagattatg actccccgca
    10501 atgatccaag tgttagtgta ggggcgaagg gactaactgg cgaaggttat aaagggcatg
    10561 ttttctggga tacggaaatt tttatcctgc ctttcttttt atatcagttt cctgaagtag
    10621 caaagaattt gctgctgtac cgttatgatc gattagaagg cgcacggcaa aaagcaagag
    10681 attatcacta tcaaggtgca cttttcccat gggaaagcgc acacactggt caggaagaga
    10741 cacccaaatt tgctgcattg aatatcaaaa ccggaacaag acaagaagtt gcttcagctg
    10801 ccgcagaaca tcatatcagt gcagaccttg cttatgccgt tcaagagtat gtccaagcaa
    10861 cagaggatca atcgttttta gaaacaaagg gaaaaacgct cattcatgaa acagcagctt
    10921 tttggctgag cagagctgta aaagtcgatg atcatttaga gatacacaga gtcattggtc
    10981 cagatgaata cacagaatat atcgacaata atgcatatac gaactatctg gcgcattata
    11041 atgtggcctt agctgttaaa tatcaagctg gcgatccgct ttttttgaaa gaatgtcaaa
    11101 attttttaga taagttatat ttgccagtgc ctaacaaaga acagctgatt ccgcaagatg
    11161 acacgtatct cagtaagcca gttattgatt tgaccactta caaagaacgt cctggcagcc
    11221 agtctatttt acttgattat gcccgtagcg aagtaaatga actccaagtc agcaagcaag
    11281 cagatcttgt catgctgtta tacttattac ctgagtattt ttctcaacca atcgtttcta
    11341 agaatttgca ttactatgaa aacaaaacaa tccacgactc atcgttgagt aaagcgattc
    11401 acgccataga ggcttgccgt atccaagaaa tggaatgggc gtatcattta ttccaagaag
    11461 cgtgcctgat tgatttagga ccagatccgc attcatcaga tgacggaatt catgctgctt
    11521 cattaggagc actatggcta gcagttatat ttggtttttc aggtattaca gtaacgaatg
    11581 gaactctttc tatttctcca agacttcctt cagcatggga aaaaatttct tttcctttta
    11641 tttggaaaaa tcacaggttg ctatttgttt tgacaaaaaa acaaatagta ataaaaaaag
    11701 agacgaaaga aacattacct atttttgtca atggagacca ataccagctg gaaaaagaac
    11761 tgatcttgga acggagggga aaataatgcg tattctgatt gcgccagatt ctttcaaaga
    11821 aagtctgaca gccttagagg cagcacaagc cattcaatca ggttttcaag aagtttttgt
    11881 tcaggctgaa tatgatctgc tacctatagg cgatggagga gaaggaacgg tttcatcatt
    11941 agcagacagt ttaaggttga agcggcaaac agcagtcgtt actaatgcat ttggcaaaaa
    12001 caaagaaatc cagtacgctt cagacggtca aactgcgatt tttgaaatgg cagaaatcgt
    12061 cggattgaaa gatgtcccac taaaccaaca acagccactt aggttatcca cgcgaggagt
    12121 aggagaactg atacgacaat tgttgcaaca aggtgttcga cacatcatca tcggcgttgg
    12181 cggaagtagt accaacgatg gcggcatcgg catggcagaa ggtctaggtt atgcttttta
    12241 cgatcaagat aatcaaaaag tagaagcact gggagaaaat ctaggtaaaa ttgctacagt
    12301 tgataaaacg aacgtgccta ttgagctgat taaagccaaa atcactgtca ttactgatgt
    12361 tactaatctt ttatgcggaa aagaaggcgc ttcttttgtt ttcggaccac aaaaaggctt
    12421 gaaagaaaat gaattagcag tggctgacca agccatgcat gatttttata tgagatttgc
    12481 ccctcaagta atcgaggcat cgggcagtag tgctggtggt ggaatgggtg caggactgtt
    12541 agcatttgct tcagggaaaa tagtctctgg catcgactac gtattggatt tactggagtt
    12601 cgataaacgg gtacagcaag cagacctcgt aatcgtaggc gaaggacgtc tagatggaca
    12661 aagtctaaaa ggaaaagcgc cagttgggat tgctagaaga gtaccagagg gcgttcctgt
    12721 gatagctatt tgcggaagtg ttggtaaagg aagcgaaaaa gcagcagatg ttggcatttc
    12781 ggccgttttt ccgatccttc ctgcagctgt gcctttacaa gaagctttac agcaagccac
    12841 tgataatctt catcgcacag ctaaaaacat cgcatcttta cttcaagtcg ttcattttca
    12901 aggaggtaat cgatgaaaat caaagcagca ctattcgatt tagatggcgt tcttgtagac
    12961 acagctcgtt atcattacga agcgtggctg gttttagcta accagctgtc cattccattc
    13021 actgagaaag aaaacgagca actgaaagga atatccagaa ccgagtcact agagcgattg
    13081 ctgtcatttg gaaaaatgga acagaaattc tcagaaaaag agaaatcagc ctttgctgag
    13141 caaaaaaaca atctatatct tcaagcgatt caaaaaatgg atgaaacatc cgttttgcct
    13201 ggtgcaatag ctgttcttga gtacttgaaa aaaacaaaca tcaagatcgg attgggatca
    13261 gcaagcaaaa atgcacgcct cattttagaa aaaacgaatt tgacaagtta ttttgatgtc
    13321 cttattgacg gcacgcaagt atcaaaagca aaacctgatc cagaagtttt tctcaaagga
    13381 gcacagcaat tgaatgtacc gccaaatgca tgcttggtca ttgaagattc agaagctggt
    13441 tgtcaagcag ctttggctgg taacatgcat gtattgggaa taggtgaaaa cataaatctt
    13501 ccttctgctg aatatgtgat tcctgattta accgtttttg atcaagtacg ttcgttttgg
    13561 catttatcag aagccgtatc acgtatataa tagtttccgt tttttctgtc acaagcaaaa
    13621 cgttatcctc cttttggaaa tcaaggtatg atgagaaaaa agggggattt tatatgacaa
    13681 aaaaagcagt tttcgcaggc ggatgctttt ggtgtatggt caaaccattt gaagagcagc
    13741 cagggatcat ttctgtgaca tccggttata ctggcgggca tgtaccaaat ccaacttatg
    13801 aacaagtaac aacaggcaca acagggcata cagaagcagt agagatcgaa tatgatccag
    13861 aagttatttc ttatgatcag ttggtggaaa tctattggca gcaaaccgat ccgactgacg
    13921 cattaggaca gttcgctgat cgcggtgatt cttatcgtcc agtgatctac tataatgatg
    13981 aagaagaacg aaatattgca gagcgttcaa aacaagcatt gcaagacagc gggcgattcg
    14041 ataagccaat cgtgacaaaa atcgaaccaa gaagcgaatt ttatcctgca gaagattacc
    14101 atcaggatta ttacaagaaa aacaagctcc attacaatct ttatcgagaa ggttctggac
    14161 gtgcaggttt ccttcgtcga cattggggcg tcaagaaata agaagccgaa aaagctactt
    14221 atggaacacc gtatatcaga ggttgtaaaa ccagcatttt gagctaatac tgagggtcag
    14281 ctgattgaac accatttagt ggagaggttg tgaacctgtc gcctagctcc aagtcacaag
    14341 gatttggtaa gagaacacta tatatcagag gttgtgacaa gtcgtttgtc acaacctttt
    14401 ttcaatacct aagatgaagg acaatcagca acgcactgct caaaaaagga atgaaaggca
    14461 gcttttccaa ctttttttta tgacagataa agtaaacaga aaaaacggat attccaaaca
    14521 gactagcaag aaacaagatc tgaagcaact cttctagaga caagccacca ctccaagaaa
    14581 gcatcaacag agtatcgcca gctccgagat aggattgacc atagcgaagg cacacaccgc
    14641 ctacgataaa cgttaacagc acactttgcc attggaagac gccggcctgc aaccaaaaaa
    14701 tccataaaat tgcccaagaa cagaatagcg tgtgagaatg gaccatgaag taaaataaat
    14761 ccatcaacga aaatagcaaa gccgaaagca tccatatgaa cgtcgaaaaa tttcttgcgg
    14821 aagaaaaagt aaagaaccag gcaaaaagac caccacataa ggcttctgcc aacaaatagt
    14881 agaagggcaa ccgacacctg caatagcggc agcgaaatcg ttggacgatg atcgagagaa
    14941 tcggaatcaa ttcataccaa gaaagcgaac gacagcattt gacacaatga gatctaggat
    15001 aaataataga gtgacctaac ggaatccgct gggcggttaa acataaaaat gatccgatac
    15061 agcaaccaat gataaaataa agtaacacgc catctccccc ttttcaaaac caagatacgc
    15121 aagcttaaac taaatttttg tacatacata aaatttgagg tgaaaaaatg aacgtttcaa
    15181 tcggattaga tatcggaacc acacaaacca aagcagttgc tttcacagat gaagcccaag
    15241 aagcagcatc cgcttatttt cgctaccctt tgatccaaga aacacaaggg atggcagaac
    15301 aagatcagga attgatcttt caaggtgtct gcaccgttat aaaagaagta attaaacagt
    15361 tgccttcaga cacaatcatt caatttgtct ccttctcctc tgcgatgcat ggcctgatat
    15421 tgttggatga agagaaaaca ccgttatctc gaatgatcac ttgggcagat aaccgagcag
    15481 cggacgaagc agaaaaactg aaatataccg tgcttggcaa agaattttat cggcagactg
    15541 ggacgccgat tcatccaatg acaccattga acaaaatcaa gtggctgcaa aacagccaac
    15601 ctgaattatt caaaaaaact gcttattttg tcggtatcaa agactatatc ttttatagat
    15661 tgtttggcga actgatcagc gactacggaa cagcttcagg aactggatat tttgatatcc
    15721 atgaattcca atgggcagaa gaagtgcttg actacttgaa cattcgaata gagcaattgc
    15781 cgcaagtctt tccttccacc tatcaagtaa caggtctacc atcaaaaaca gcagcagaac
    15841 taggtttgcc aaatgatata tcatttgttt tgggaggggc agacgggccg ctttctaatc
    15901 tagggttagg tgcttttggt gatacgatcg ccgctttgac cgtaggaacg agcggagcac
    15961 ttcgttttat tactactcag cctcagttcc atccagaaat ggagacgttt tgttatgttc
    16021 tggatcagaa acattgggta gtgggaggag cgactagcaa tggtgctggc atctttgatt
    16081 gggcagggca tacattttta caggaagtcg ttcaatctgc taaagaaaaa ggagaaaatc
    16141 catatgatgc actgctttcg gctatcgctt ttgtgccagc gggtgccaat ggtctgattt
    16201 ttcatcccta tttacttggt gagcgagcac cgctttggga cgcagatgcg tttggcagtt
    16261 ttatcggttt acagcggcaa catacagaaa aagaaatgat gaaggcgatt ctagaaggga
    16321 tctgtctcaa cctttatcgg attttaaaag gagtttgcca ggaaaatcag ctcacagaga
    16381 tccgtgctac aggcgggttt gctcaatctc cgatttttcg tcagatgatg gctgatgtac
    16441 tgggttaccc gcttgttttc cctactgtca cagaagcatc cgcattagga gctgtgattt
    16501 taggctggag aagcatcgga aagatccaaa gtatcagtga agcacaggaa ttgatagaat
    16561 tgaaagagca agttggagta caagaaactg atcataaaaa atatcagaaa atctatccat
    16621 tatttgtttc gacacaaaag catttagcac agacttatca gcaatttgct caactgcgag
    16681 aagaattagc tgattctgaa aaatgattgg ctttacggat aaaaaagcga actgaaaatc
    16741 gttctcaggt aaatgatttt gttgtacttt tcattgaaag tctactatta ttttaagtgt
    16801 aagaaaatgt taggaggcaa gaaagatgaa attccaacaa accaaagaag tattaaatca
    16861 attagttgca gatctaagcc aaatgtctgt tgttgttcac caaacacatt ggtacatgag
    16921 aggaccaggt ttccttacat tgcacccaat gatggatgag ttcatggatg atttgaacgc
    16981 tcagttagat gaagtatccg aacgcttgat cacattagac ggttcacctt attctacatt
    17041 gcgtgaattt gcagataaca caaaaatccc tgatgaaatt ggccgctggg atcgtactat
    17101 tccagaacgt ttggaaacac ttgttgcagg ctatcgttat ctagcagatc tttaccaaaa
    17161 aggaatcgaa gtttctggag aagaaggcga cgatccaaca caagatatct ttatcgaatt
    17221 caaaacagcc acagaaaaac gtatctggat gatccaagct catttgggca aagcgccaga
    17281 gatcgacgcg taaaaactgt tgttgaactt gaccgaaaaa gaggttgtga aatcagcgtt
    17341 ttgacctgag tattagagaa acaaacgtca aaatagttcc tcatattttg ccgttttttg
    17401 agctaatacc gagggtcagc tgattgaaca ccgtttacca agaggttgta agcctgccgt
    17461 tcagctccga gtcacaagaa acaattttaa aaaacagctt cttatgtttt atggatattg
    17521 tgacttgtga ccgaggagtt ggcaggagaa caccgtttat tcaaaataag gggttgtgac
    17581 aagacttttg tcacagcctc tttttgtttt tcattttgac aggaaacgac ccttttatat
    17641 aaaagaaaga aaagaagtaa agtttcatat aaatttttca atcaagcaga aaaacgttga
    17701 cattgactag attagcgggt aatatgttaa atggtattgt ttgccccaca aagagccccg
    17761 gaaactcgaa gtgtatgtca aacatcagaa cttaaattgg aggaaaataa cgtgcgtaca
    17821 acatatatgg ccaaaccagg cgaagtagaa cgtaaatggt atgtagtaga cgcaactgat
    17881 gttccattgg gacgtctttc aacagttgtt gcatctgtac tacgtggtaa aaataaacca
    17941 actttcacac ctcatttgga tactggcgat ttcgtcatcg tcatcaatgc agacaaagtg
    18001 aaattaacag gtaaaaaagc gactgacaaa atttattacc gtcacagcaa ctacccagga
    18061 ggattgaaat caatcactgc tggcgaattg cgtgctaaaa attctcgtcg tttgatcgaa
    18121 acttctgtaa aaggtatgct tcctaaaaac actttaggcc gcaaacaatt tacaaaattg
    18181 aacgtatacg gtggagcaga acatccacat gcagcacaac aaccagaagt tttagacatc
    18241 acaaacttaa tctaatagga gggaatttca ttggcacaag ttcaatatat cggcacaggc
    18301 cgtcgtaaaa acgcagttgc tcgcgtacgt ctagtaccag gaactggcaa aattactgta
    18361 aataaaaaag atgttgaaga atacattcca catgctgact tgcgtgaagt aatcaatcaa
    18421 cctttcgctg ttactgaaac aaaaggcgca tatgacgtat ttgttaacgt aaacggcgga
    18481 ggatacgctg gacaatcagg agctatccgt catggtatcg ctcgtgcatt gctagaagtt
    18541 gatcctgact tccgtttagc tcttaaacgt gctggcttac ttactcgtga cgcacgtatg
    18601 gtcgaacgta aaaaaccagg tcttaagaaa gcacgtaaag cttcacaatt ctcaaaacgt
    18661 taatatcctt tatatatcaa cgtttctggc acttttcaat tatttggaaa gtgcttcttt
    18721 tgtttttaag aacacattta agaacacata tcaatcacac ttattcaatc ctctctgaaa
    18781 agcttcaaaa acagccttat caactatatc tggtgtgttc acatatatct ttgttgtaga
    18841 aatatctgag tgtgttaaag catttgaaat ttgattcata tctgctccac cttgtctagc
    18901 tatagttgca taagtatgac ggagtttgtg tggagataaa tgaactaagt caggatgcct
    18961 tcttttaatt gaattgattc gatagtttag gtaatcggca tgaacaggac aatttacttc
    19021 tccagatggt ttagtataag taaagagata ctgatctaac gtttgcttaa tttttaattt
    19081 caacaattga tcagcttgta ccgatttcca ttcacttagc aatgtcatta caacttctgg
    19141 tacttgaatg acggtatctt ttcgaccttt tgtaaacttt tttctttgat atttatctaa
    19201 agtatgttta agacggaccg tttgtttttc aaaatcaata tatttccatt gcaaagcgta
    19261 agtctcactt tttctatcac caagatacag ggtaatcata aaaagtgtgt aatcatgaaa
    19321 agtaagtaaa tgattattaa aatcatcatt tactgcttct atccaattag taagttcttt
    19381 tgatgatagt gcttgcttac cttcttgtat tcttttttct tctaaagcat tttttttagg
    19441 tgcagtgata ctttgaataa ttttagtagt tcgattaaat tcgatataat ttagtatttc
    19501 tgcaatatcg aacatggaac gaacatatcc ttttatgatt tttatatttg catattcttt
    19561 cgattttttg gttaattcat ctgatattat ctcagtattg atatttagat aattcattgc
    19621 gtattcacca aacataggta aaatatgcaa ccgaaatata tcttttgtat tactaatggt
    19681 tatatcacta ggaggcctgt ttgatctaat tgtttgacct aattcatatc taggaagcca
    19741 tttagattcg taaaattttt taaacgttat ttttcctttt aattctaatg agtttgcatt
    19801 ctcctctctc aaaacttttt ctattttctt cttcatatca ttttcggctt taatcgccaa
    19861 ttgcctattt ggaaatgttt tttgatactt ttctgatgca attcctgtta tttctttaaa
    19921 cctttttgga tatctcagat tagttttata tttcccattt gaaagctttg taggcaaaat
    19981 cctcactcct taaaaaaagt aaggcagtat atttcactaa ttttagtata tgcggcgaga
    20041 agaaaatttc aagttatttt aaatgtattc ataaagtctt taatatcttc tacgtcaaag
    20101 cgaactacac caccaactct tattactggg aaattatata tacgaatcca cttatctaga
    20161 gtattattat cgattcctag aaatgcacag gtttgttttt tattcaggta gactctggat
    20221 tctataaaat catctcctaa aatagtagtt atgaaatttt tgaattgctt tgggtaagca
    20281 cataggaatt tcacctctcc ccagtttacg gcgagcctta cggaagtatc attatttgct
    20341 gctattgtca tggcattttg ttttcccaga acaaaaagaa atctctaagt atttgtcgct
    20401 aatcaggtca tggcgtactt gagtttctag ctcgaatagc agggatcgtt attcaaaaat
    20461 tgtatttaat tgtcaatgat caaaaatagt ttttttccta ttcactatta ataacgataa
    20521 acatgtataa aaagacacac tacgaaaaaa gttaaatgga gtttactgat tttcatattt
    20581 gtatatggaa cagacatagt cttgaataat ttttataaat gttttgatgc ttatcaactt
    20641 attcaacccg ctatccactt caagtataat ttttccatac gccaataaag tagttttagg
    20701 agcatgttct catttgagaa cgctcctttt ttatatattt tgaaagctac ttactatacg
    20761 cgtagtttca aatagttttg tcattctaat cttcagcaac agaaaaaaat ctaaactata
    20821 aaatttaggg ttgactaaaa tataattttt gtataccata tgatcgtgat aatcattatc
    20881 atttagaagg agaaagttat gttagaagtg aaaaagctta atgtttgtta taacgatttt
    20941 ttagcattga acgagatttc tttaaaaata caagaaggtg ct
//
LOCUS       DAXLPC010000047        20410 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.047, whole genome shotgun sequence.
ACCESSION   DAXLPC010000047 DAXLPC010000000
VERSION     DAXLPC010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.047"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            287..1987
                     /locus_tag="ACF3UE_001638"
     CDS             287..1987
                     /locus_tag="ACF3UE_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635043.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNIRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFNKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKHLRA
                     "
     gene            complement(2089..2922)
                     /locus_tag="ACF3UE_001639"
     CDS             complement(2089..2922)
                     /locus_tag="ACF3UE_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFD3635044.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLAKKTLESQVLTVSQSQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEEGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(3472..5637)
                     /locus_tag="ACF3UE_001640"
     CDS             complement(3472..5637)
                     /locus_tag="ACF3UE_001640"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFD3635045.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNRQADS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLEVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            5897..8191
                     /locus_tag="ACF3UE_001641"
     CDS             5897..8191
                     /locus_tag="ACF3UE_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFD3635046.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFAGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEATITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            8184..8849
                     /gene="pgmB"
                     /locus_tag="ACF3UE_001642"
     CDS             8184..8849
                     /gene="pgmB"
                     /locus_tag="ACF3UE_001642"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFD3635047.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDRTFNEQLK
                     GVSREDSLSLLLAHGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            8842..9849
                     /locus_tag="ACF3UE_001643"
     CDS             8842..9849
                     /locus_tag="ACF3UE_001643"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFD3635048.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEELPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRKMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            9871..10890
                     /locus_tag="ACF3UE_001644"
     CDS             9871..10890
                     /locus_tag="ACF3UE_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3635049.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDPVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(11171..12538)
                     /gene="nhaC"
                     /locus_tag="ACF3UE_001645"
     CDS             complement(11171..12538)
                     /gene="nhaC"
                     /locus_tag="ACF3UE_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFD3635050.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(12647..14068)
                     /gene="tyrP"
                     /locus_tag="ACF3UE_001646"
     CDS             complement(12647..14068)
                     /gene="tyrP"
                     /locus_tag="ACF3UE_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFD3635051.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(14311..16188)
                     /gene="tdc"
                     /locus_tag="ACF3UE_001647"
     CDS             complement(14311..16188)
                     /gene="tdc"
                     /locus_tag="ACF3UE_001647"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFD3635052.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FTDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(16479..17735)
                     /gene="tyrS"
                     /locus_tag="ACF3UE_001648"
     CDS             complement(16479..17735)
                     /gene="tyrS"
                     /locus_tag="ACF3UE_001648"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFD3635053.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEVEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(17847..18052)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            18315..19616
                     /locus_tag="ACF3UE_001649"
     CDS             18315..19616
                     /locus_tag="ACF3UE_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFD3635054.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(19685..20284)
                     /locus_tag="ACF3UE_001650"
     CDS             complement(19685..20284)
                     /locus_tag="ACF3UE_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3635055.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT         6182 a         4281 c         3659 g         6288 t
ORIGIN      
        1 ttatgttttg agtaataaga gcgctagtca gaaaatagct tttcatattt tctaggctag
       61 tgagcttatt accgagaagc agctgattga acaccgttta ccgagaggtc atgaaaaagc
      121 tactttgttt cgagtattaa gaaaaattct gtttcaaaac aaggagatgc aacaaaactt
      181 atgtcgcatc ctctctcctt agaactttca cttatgtttt tcttgtaaaa ttcataaata
      241 ttttcatgaa ttttctaatt tcttgcctac ctctcgcata ggatatatga tgaatttatc
      301 taaagtttgc aaaggagttc gacaattgaa aaaatatggc ccatttttag caattttttt
      361 cattgctttg gcatttctca tgcctcattt attcacacat aaactaattt tgggtgctga
      421 tgccccattc cattacaatc ggttctatga tgccgcgcaa caaattaaat atggggattt
      481 ccattatttt ccttcccttt atggattcca gcaaagtggc aggatcgtga atgccgttta
      541 cggcccattt ttcgcttatt tacaaggatt gatcgtgttg cttgcaggta gctggtttca
      601 ttatcagatt ctttcaaatt tcattcttta tcttatttca ggattttcta tgctgatttt
      661 actgagatat gtcaatattc gaaattgggt aagtgtacca gtagccgttt tattcatgag
      721 tacgtattct attcaatact ggtctatcaa ccaaggattc actagctggg ggacttgttt
      781 ttatccttta tgtatgatcc ctattgctga tttcgtcctt cataaaaagt ttcctgttat
      841 caaagtcgct gtctcagtgg gacttatgac acagatccat ttactgtctt cgatcatgtt
      901 agctttgatg tatattcctt tttatcttta ttactttttt aaccagactg aaaaaggaaa
      961 agcactgctt caactgatta agtcggtctt gctttatttt gttctgacag caaatatttg
     1021 ggcaggatta gctattgttt acagtgggaa taagattctt cctccctttg ttaacagaga
     1081 aatgagtcaa aaggcgatag atctggatgg cagttattgg ctccattacc ctaaggcctt
     1141 tcctatattg atattatcag gttttttgct ttttattttc tttcaacaaa agaacacctt
     1201 attccaaaaa atcgtgttgt acacaagtct tgttttcttt tttctttcta ctagcttgat
     1261 tccatggacg acattgatcg aaaaaaatgt gccttttatt agtttgatcc agtttccatt
     1321 tcgatttttc gtgccattta cgctattgct tctactttac cttgcccttt cactgaacca
     1381 gtggtctgaa caaaagtggt tccgtctttt aagtatattt ggcattctta ttttttcagc
     1441 acagacgatc cagaacttat accagcatct ggaaaagtgg gaaaatgaaa catttgtcag
     1501 tcgacatact tatctattcg atacgccgga agaagcaagg aaaacattct tcaacaaaga
     1561 tatgtctacc agcttgttcg ttttccaaaa aaccacacct gactatctgc caatctataa
     1621 ggagacaaaa gacaataaat acgaccggta taacgaagaa atactagaaa acgaaacaac
     1681 ttttataaaa acacatccag gcggtcttct gacaatcaag tggaaaaaca ctggggacaa
     1741 aactgttcat atccctgtta tcgtctacga tcggactgtg ctacagcaaa atggaaaaac
     1801 attgactgat tatgaagtaa cagatatcgg gaccccaatc gtgaagcagc aaaaaggaat
     1861 caacgagctc acgcttcatt atcaaacgcc aatctatttc tatttcattc tttctcttac
     1921 tttgattggc tggtttacct tgctatgttt atttatttat catagataca agcatttacg
     1981 tgcttaggca aaagggataa atgcatccga tcaaaaaact ctccaaacgg tataatcgtt
     2041 tggagagttt tattttaatc agttttttta tgttatatgt tatatttttt attcgttcac
     2101 atctaattcg atttccaccc cgtagtgatc actgatgatt ggactatcga tcccatcaaa
     2161 aatccgttga tattttttaa cctgcattcc ttcagggacg aaaataaaat ctatacgcaa
     2221 tttttctgta ttttgttccc aaccatcgat tttcttttcc acagtagctg cttttccttc
     2281 ttcattcgcg acaacatacg aatcttgaag aagaaggcaa ctttctctta cagtataata
     2341 accttgagag tctactggat tattgaaatc acctaggaaa aaaagtggta cgcgagtttc
     2401 caaaaagtag ttttccaagt ttttccactc aaaataaaag ccactttttt tatctgtcca
     2461 ccaagaaaag tggcagctcg agacaaaaat gtcctgatca tctatctttg ttttcccaat
     2521 caagatcttg cgtgtctgat aatcttcttt cttttgagat tgggagacgg taaggacctg
     2581 actttccaat gtttttttcg caagcagtgc atttccttct tcatatttat cataaccgat
     2641 gtggctcatt tcccaactcc aaaaatactc ttttccgtgt tcctttaaaa gctgaactaa
     2701 acggtaggca aaattatctt tacggatagg tacttgattc tttaccggac agaacttcat
     2761 tagcttcgca ggttctactt cttcagattc cagtaattgg ttgatttctt gtaaagcaat
     2821 cacttcataa tcttctaaca ggatcttatc tgctaattct tgcaattttt tctctggttc
     2881 tggctcaagc cagctatgcg tgttgagtgt catgaatttc attggttttc tccttgtctt
     2941 catttcgaaa caaaagggtt gtgacaaaat ttttgtcaca acctctccag caaatagtgt
     3001 tctcctgcta actcctcagt aataagctca atggaccagg agctattttt tgtttggctg
     3061 tttttatcac ttggtgcagg gcagcttttt cacgacctct ccactaaaca gtattcaaac
     3121 tgctgcttct cggtaataag ctcactagcc tagaaaatat gaaaagctat tttctgacta
     3181 gcgctcttat tactcaatgc ataacgcagt tttcacaacc tcttccttaa acggtgttca
     3241 aaagcttgca tctgcggtaa taagcccaac caaacgaaaa ataggaggag ctatttttgt
     3301 ttggctgttc ttattacttg atgcaggaca gctttttcac aacctctcga taaatggtgt
     3361 tcaatcagct gaccttaggt attagttcaa aaaacggcaa aatacgagga gctgtttttt
     3421 cgttttgttt ctctaatact caggtcagga caatgatttc acaacctctc cttacatttt
     3481 aatggagccg atcactttac cagctgtcac tgtacctaat tgcttgatca ctacttcttc
     3541 tactttatcg tttgtaaata cgatcatgat cgttggatct ttttcttcat tttggatcac
     3601 ctcaagatcc atctcagcta atttcgttcc tgttcctact tcttggcctt ctttgacagc
     3661 aatctcaaaa gctggctgat tcatttggac tgtatcgata cccatatgga tcaaaacttc
     3721 gataccatct ttcgtctcca gcccaattgc atgtttgctt gggaaaatac ttgtcacttt
     3781 tccagcgatc ggcgcaacaa cttctcttga tgttggaata acagcaaagc cgtcacccat
     3841 cattttttgt gagaataccg gatcttttac ttcagataaa ggaatcactt ctccagaagc
     3901 tgcggaaact agttcttgtt ctatacctaa gtattgctta ctatctgctt gtctatttcc
     3961 tgtagaaacc atttctggct ctggaatctc tgctcctgat tgcagcagat cttcgatatc
     4021 tgatttcaag acatctgctt ttggtccata aactgcttgg actccattgt ctttgacgat
     4081 caatcccatc gcccctgctc gtttccaggc ttcttcagtc cctacttttt ctcgatcatt
     4141 tacacttacg cgtaaccgag tcatacaagc atcgacatct ttgatatttt cttttcctcc
     4201 cagcaaatga atgatctgga ccacttgctg atctgctgtt cctgttccgc tgttagatac
     4261 aacggtttct tcactgtcat tgtcgtaatt tccgttacgt cccggtgtag caaagttgaa
     4321 ttttttgatc aagaaatttg ctaagaaata cgtaacaaca ccaaaagcga tcacacacaa
     4381 cacgaagttg ataagatctc cacctaaacc cgctttgata gctaacggtg tccgagtcag
     4441 caattcgata ttcccaaatg aatggacccg caatggcaag atatctgcca tcgcaaatgc
     4501 agccccttgg atcactgaat aaatgacata taatggcaca gcagcaaaca taaacatgaa
     4561 ctccaatggt tctgttacac ctgttagaaa gacagccaac gctgctgaaa aatacattga
     4621 tttatatctt gctttcttat caggatcgac attacgatac atcgcaaaag ccattcccat
     4681 caagatacct gaagaaccaa tcatttgtcc tactttgaaa cgagccggcg tccagttatg
     4741 caacacaaac tcatattgcg acatatcccc tgcaccttta agattcacta aatcagtggc
     4801 ccaagccaac cataacggat cttgcccaaa tacttgtgtc cccgcctgtg cgcctgataa
     4861 aatctcatac gatccgccaa gctgtgtata gttgatagga atcgtcagca tatgatgcaa
     4921 tccaaatggc aatagtaaac gttctaatgt tccaaataaa aacggtgcta gaatcggtgc
     4981 gctttcttgt gattctgcga tccataaacc aaaattattg attccagcct gtacgtttgg
     5041 ccacaccaca gcaagaatca atgccacgat tgttgaccat aagataacaa caaacggaac
     5101 aaagcgcttt ccattgaaaa atgacaaagc atccggcaat tttctataat tatagtactt
     5161 attataagcc attgccccga caaatccagc gatgatccct acgaatactc ccatattcaa
     5221 agctggtgct tccaatacac ttgtaaaaaa tcctttaacc atgatcttcg taccgaacag
     5281 agtgtgggta aatgcatctt cattcgcaag catgtcactt gtgacaccaa agatagcccc
     5341 agtgatccga ttgatcaaaa taaatgagat cccagctgca aatgctccgc ctgctctttc
     5401 ttttgcccaa cttcctccta ttgctaaagc aaataaaata tgaagattac caataattgc
     5461 ccaaccaata ttttcaatta ctccgcctgt tgtgacaagc ggcgtccaat caggattgat
     5521 caagggaatt gatttcccta tactgatcat caacccagct gccggcataa ctgctaccac
     5581 aaccattaaa gcctttccaa atttttgcca aaactcaaaa ctaaatatct ttttcattcc
     5641 gtttagctcc tttacgcaat cggtttcgtt aaacgtatta tagcgtgcgt tttctttttt
     5701 gtaaatgctt tattttttat ttttctgtct ataccattct agaaaaccta taatgcgtgt
     5761 gttcccttct ataattttct cctaaaaatt tattttttta tgcttttttc tatgaaatat
     5821 tttcttttgt ctattgactt gtgcaatcgg ttgcgtttat tatgaacgta taaaacagct
     5881 cattaggagg agaaaaatga aacagatcaa acgactattt gctattgatc catggaaaat
     5941 cagcacgaca caattagata aaaaaaatct tcgactgcaa gaatctttaa caagtattgg
     6001 aaacggttat atggggatgc gcgggaactt tgaagaaact tactcagggg accaccatca
     6061 aggtacttat ttggcgggtg tctggtatcc cgataagaca cgtgtcggct ggtggaaaaa
     6121 tggttatcca gaatactttg gaaaagtgat caacgccttg aactttatcg cgatagatat
     6181 ttcgatcaac gatcagctga tcgacttggc ttctttggaa ccagaagact tttactggga
     6241 attagatatg aaaaatggtg tattatctcg tacattcaca atcactactt ctactaataa
     6301 agtacgcatt tccttcgaac gttttctgag cattgtcaaa aaagaatcag cttatatcta
     6361 tttaactata gaaatgcttg aaggtagcgg aacagtcaaa ctcgtatcaa aattggatgg
     6421 aaatgttcaa aacgaagaca gcaactatga tgaacatttt tggaatgaga ttgatcgtgg
     6481 aactatagaa gaaatcggct atttgacgac taaaactatt ccaaacaact ttgggattga
     6541 acaatttact gttactgcag caatgcgcca tttcgttaat ggaaaatcag tcatccctga
     6601 ctatcacgaa gatactttag cattacatgg ttgcttgtct gcggaattat ctcaaggtga
     6661 gacatggtca gtggaaaaag aaattatcgt tcttactagt agagatattc cagaagcgca
     6721 gcaagcagaa aaagctgtct cagaattaac gaaccagaca aacaattata tccaagcaaa
     6781 agaagagcaa acagcggctt gggcagaacg atggaagctt gccgatgtgg tcatcgaagg
     6841 agacgaagaa gcacaacaag gtattcgatt caatttgttc caactattct ctacttacta
     6901 cggcgaagat gaacgattga atatcggccc caaaggattc acaggagaaa aatacggcgg
     6961 agccacttac tgggatacag aagcgtatgc tgtccctctt tatcttgctt tagccaaacc
     7021 tgaagtaact aagaatctgc tgaaatatcg gcataatcaa ctgccgcaag caatccacaa
     7081 cgctcagcaa caaggattaa aaggcgcgct ttatcctatg gtcaccttcg ctggtgtcga
     7141 atgccataac gagtgggaaa tcacattcga ggagattcac cgaaatggcg cgattgccta
     7201 tgcaatctac aattatacga attacaccgg cgatacggaa tatttgaaaa atgaaggact
     7261 ggaagtttta gcagaaatag cacgcttctg ggcagaccgt gtccattttt caaaacgagc
     7321 aaataaatac atgatccacg gtgtgaccgg cccaaacgaa tatgagaaca atatcaataa
     7381 caattggtat acaaatacga tcgcagcttg ggtcttgcgt tacacgcgag aaaattattt
     7441 aacttatcaa aaagaagcta ctatcactat cagcgaagaa gaactagcca aatggaaaga
     7501 tatcgcagag aacatgtact tcccagttga cgaagaatta ggaatctttg tccagcatga
     7561 cacattctta gataaagatc tcatgcctgt atccgatatt cccacaagcg atcttcctct
     7621 aaatcagcat tggtcttggg acaaaatcct tagatcttgc ttcatcaagc aggcagacgt
     7681 actacagggg atttatttct tcaatgatac ttttacaaaa gaagaaaaac aaaaaaactt
     7741 tgatttctat gaaccaatga ctgtccatga gtcttccctt tcgccaagta tccattcgat
     7801 tttagcagca gaattaggaa tggaaagcaa agctgtagaa atgtaccagc gaacagctcg
     7861 cttggatttg gataattaca ataacgacac agaagacggc ttgcacatca cttccatgac
     7921 tggtagctgg ttgtcgattg tccaaggatt tgctcaaatg aaaactgccc atgatcagtt
     7981 gagattcgca ccatttctgc caaaaacttg gaaagcttat tctttccata tcaattatcg
     8041 cggacgttta ttgttcatct cagtcacaga tgaacaagtt actttcgagt tattagaagg
     8101 ttctcctcta gaaatttacg tctatgaaca gtcttattct ttagcggatc gtctagaaat
     8161 aacgctaaga aaggaggaag caaatgttta aaggggtatt gtttgattta gacggtgtca
     8221 ttaccgatac tgctgaattc cattatcgtg cttggcgaaa gcttggtcag gaaatcggca
     8281 ttacgatcga tcgtacattc aacgaacagc taaaaggcgt cagccgagaa gactcactct
     8341 ctttgctttt agctcatggc ggaaaagaac actctttttc aaaggaagaa tttgcagaat
     8401 tagcgaaaag aaaaaacgat tattatttag agatgatcca gacgatcgaa ccaaaagatg
     8461 tcttccccgg agtcgtgcct ttactagatt ctttaaaaga agaaaaaatc aagattgctc
     8521 ttgcttctgc aagtaaaaac gggcctttcc tacttgaaaa aatgggtctt acaccttact
     8581 ttgatgctat tgccgacccg gcagaagcaa caaacggaaa acctgcgcca gatatcttcc
     8641 tccttgcagc aaaagctgtc ggactaaaag cagaagaatg tatcgggatc gaagacgcgc
     8701 aagccggtat ccaagccatc ctctcaagtg gcgctcaacc aattggcgtg ggacgtgctg
     8761 aagaccttgg agaggagatc ccgcttgtcc ctgatacgac ttttcttacg atcgattact
     8821 tgaaagaaaa gtggcatgac catggataat ccagaaatct ccgtcgtacc agttccagag
     8881 actgaaataa agaaaatcac attgaagaac gactacttag aagtcgttct tctcaattac
     8941 ggtgcccgcc tgcaccaaat cttcgcacca gacaaagaag gaaaatcaga aaatgtttta
     9001 ttgtcttacg atcgtttcga agatgttcta acagacaaaa gcttttttgg agcaactgtc
     9061 ggacctgtag ccggaaggat ccgggatgct tcttggggtg agcatagatt ggagaaaaac
     9121 tgcggatcac accatatcca cggtggcacg aaaggctggt ctttccaatt ttgggaagta
     9181 gaagttttca aaactccatc atcaataggt gtggtctttt acttaaaaga tgaattttct
     9241 acctatccag gaccaatcac tgctacgatc acttaccgtt taacaaaaaa cgaattagag
     9301 atgacaacct ctgctagtag ccttgttgaa accatctgca atccgaccaa ccatgcctac
     9361 ttcaaccttt caggaaatgg aacaagagac atctatgaac atcagttaac ggtcttttta
     9421 gatggtgtgc ttgaattaga tcaagaaaaa ctgcctactg gaaattggac aaaaaaagaa
     9481 gaactgccaa tcgactttag aaaatcccca acactgcaag agatccttgc atgttatcca
     9541 gatggactag atgatgtatt tcttttgcat catcctaggc tttccaaaac ttccttacaa
     9601 ttattcgaga agcattctgg tcgcaaaatg actatagcaa cttctaataa aagtatggta
     9661 ttattttcta cgactggatt cgaagctgat ttctctgtca atggaaaaca gatgcattca
     9721 aactacggat tagcaatcga accgcaagaa atccctgata tcgttcattt ccccaaattt
     9781 ggatcgatca acctccatcc tggtcaagaa cggatcagtc agacgattta tcggttctct
     9841 gcacaataac aagagaaagg tgtttttatc atggctatta ccgtaaaaga tgtggcgaaa
     9901 aaagccggtg ttgccacctc gaccgtctct cgtgtcatca acgatcatcc tagtatttcc
     9961 gagacaacaa agaagaaagt ccgaaaaatt atggatgaac taggttatgt tcctaacatg
    10021 actgcccgca atctaggaaa acgcatttcc agtgccatcg gcgtaatctt accccctctt
    10081 gattcaaaag agcggatcgg taacccattt tatcttgaga tcatggaagc aatcaacgaa
    10141 gaagcgcgga attatgatat gactacagca atcgctactg ctaaaaattt tgaattgctg
    10201 ttagagaacg tccagcgtat gcatttacaa aaacaagtag atggttttat tctagtgtat
    10261 tcagatagtc aagatcctgt cattgattat ttataccaaa accacatccc tttcactttg
    10321 atcggacagc cttatcatca tgagaacgaa atcgtttatg tagataatga taaccagctt
    10381 ctaggtaaac aagcaacaga atttttgatc cagaatggac ataagaatat cctgtttgtg
    10441 acaaacacga ctcatgaaag tttgtatttc gaacgatatt tcggttatca aaaagcaatg
    10501 atgatggctg gtcttcctgc gttatccagt gtagtactag agcatccgga agattatctg
    10561 tcctttgaga aaacgttgaa agaaaacgaa gccacagcat tggtggtcat tgacgatatc
    10621 ttcgcccttc gcacgatgca gttggcgcaa atgtacggct atgtcattcc agagacactc
    10681 tccgtcatta gcttcaacaa ctcgatcttc tcaacattaa cacaccctta ccttacaagt
    10741 atcgatatcg atatctccga attaggacgt gtcgctatgc aaaagctgcg cgaattgatc
    10801 catgaagaat tgagcagtgg cgtacgtttg gtcatccctc atcgcttgat caaaagagag
    10861 acagtcgttc ctttagaaaa cccatactaa atagctgact cactaaatac gctgaccatt
    10921 tatcctatgg tcagcttttt atgtaaaaga agatactact tctaacacat tgtttatctg
    10981 taaaaaagag cgtgggacaa aagtaaagaa cacttttgtc tcacgctcta aacacgtata
    11041 aacggcggaa gcagaagcaa ctccttcgga aataagctga aattcacaaa aatttaaaaa
    11101 gcaattttct tgagtttctt cttatttctt ggagttaaac gcttctgtcc cagcctcttt
    11161 tttccttcct tcaatttttt acacgtcgac gattcaataa aaaaccgcct aatattgtaa
    11221 agacaggtgc aagaatcgag aaaaaggcga atggcaagta atgcaacgcg ctaactttca
    11281 tcgttcccat aatgaatgtg ccgctgactc cccacggtac gagagaattg acggtcgcac
    11341 ctgaatccgc tagtgttcgt gtcaaatagg tttttgataa gccaacgtca tcaaaagaac
    11401 gcttgaatgt ttctcctgga agaatgatgg acagatactg ttctccaacg atcagattga
    11461 ttccgataca gctcaaggca gtaaacccga ctaaacgaga aggtcggtcc atcttttctt
    11521 ttaattcttg aacgatggta tcaacgatca gatatttgat cagtaaccca cctaatgcca
    11581 atgcaagtaa aatcaaacta gcagaaccta acatactcat gatcccgcct cgagaaagca
    11641 gttcatctag ctttggatca ggtgtatttg cgacataacc attcatcaag atgtctgctg
    11701 cttttccgac cgtcaaactt ttctcatgga taaaagaaag aacgagagca gctgtcgatc
    11761 ccgctagtaa tgtagggata gccggaatct ttttgattgc ccccccaaat aaaataacta
    11821 gtggaatcaa tgtccaagga gagatccaaa agctcgcttt catgttttgg atcatttcat
    11881 tgatactagc tagatcggct gaatgactgt tatgtcctaa tatcgtataa aaaatcaacg
    11941 aaaggacgaa tgctgggaaa tccgtataac gcataccagc gatatgttcg aatagattaa
    12001 ctcctccaat acccgctgcc aagttggtcg tatctgataa aggcgagcag ttattcccta
    12061 aaaaggcacc ggaaacgact gcgcctgtag tcattgcatc attgaatcca agtaaatgac
    12121 cgatccccaa aaaagcaatt ccaatcgtcg aaatcgttgt aaatgaactg ccgacagtca
    12181 ctccgacaat tgcacaaaca agaaatgctg tcggtaaaaa gaaacgcaca gaaacaagtt
    12241 taaatccata aaccataatc gtagggatgg ttccagataa aatccatgaa gcaactaaga
    12301 caccaatcaa aagaaaaatc aggattggaa tgatccctgg agtgattcct ttgatgattc
    12361 cgtcatggat ctcatcccat gtgaactttt taaatctgcc ataaaacaac aaacacatga
    12421 aagctgcaag gatcgggata tgtggcgaga gctggaatcc gatgatcagt actcctagga
    12481 gtgccaacaa cacgatcaat acagcgatac tttcttttaa agaaatattt ttattcatcg
    12541 tcgatctcct atttcaaatg aaaaggccct gccatgaaaa aactattcac ttggcaggac
    12601 ctcctactaa atcagcgaca aaacgtcggc tgaaagactt atttttttat ttttcttcta
    12661 aacttttttc tacctcaatc ccccaagaat ctttcttgaa gtgattgatg atcaatggaa
    12721 taacgaacat gaccactgtg atagctgcta ctaataatgc atcactcaat gtcgctgtac
    12781 ctaatgtagc aaatacgaca acgatgatag agaagatcag catgcagctg actacccaag
    12841 ctaatccgtt tccgttttta ccaattcggt aaggacgttc gaattctgga tgtttcttac
    12901 gcattttaag caatgaaaca gcaatcaaaa tgtacacgat acaataaata acagttgtag
    12961 catttgtaag tgtcaagaat acagcactta cgtcatccat tacaccataa agcaaagcaa
    13021 ataatgaaat aacgattgat tgtgttagaa cgacatttct agatacgccg tatttgtttt
    13081 ctttatggaa tccgaatttt ggtggaagga atccttcacg agctacttgg atgattgttt
    13141 ttgatggtcc agtaacccaa gctgataatt gtaaaagcac accaataaat accatgaagc
    13201 tgaagatatt tccgatcact tctggtaagc ctaggatttg acagtcaatc aagataggct
    13261 gcgtgatatt tgctaattcc atttttccat ctggtacgac atttgctaca agcatcgcat
    13321 tgatgacatt caataaaact aatccgatca aagcgataaa tacgcctttt gtataatttt
    13381 ttgttgcgtc tttcaaacga ggcatgtaaa cagaactcat ttcgatccca acaaaaataa
    13441 atgtgatacc agctaagtat ttcaatgaat caatatgttc caagtcaggg aaagcttttg
    13501 accatgaaaa gtcacctaga tagccgtttg agactagtcc gactttgaag gctgccaaaa
    13561 cacctaaaac gaacatgatg actactggga tatatacccc tagccataca ccgatgttcc
    13621 cgccgacttt tgccatatcg aatttcaagt tcaagatcgt gatgatccag tagataacta
    13681 aaatacaacc taaaacgaac cagtgattat tgccaagttc tacattacca aatgtgtttc
    13741 ctaacaatgg tcctaaagta gaagcgacca ttaccatacc tgggaacatt tgcacccata
    13801 atagccatgc aacgacaaat ccccatttgc tgcccagtgc tgtttttacc cataactgag
    13861 gaccgccttc ttgaggaagc atcgttgaaa gctcaccgga aaccattgat atcggaccgg
    13921 caaaaaacaa aactgcaaaa attgaataaa aaatcaatgt ccaaccgact gcggctaacg
    13981 taggaatact ccgaaccgtt gcacacagtg ccattgtcag accgataaag gtcccaagac
    14041 ccattttact tacttcagat ttactcaccg ttgacactct ccttgatttt ttggataaaa
    14101 taacgatgtc tttgaagtag tttcagcaat aaacgaaaca attcagcgaa tatttgaggg
    14161 gattctttga gtctattgct tgaagggttt cttcaaagac aacctcaaaa caaagggatc
    14221 gaagagctta ggtctcccct tgctcttcag atccaaacat gcgtcagaaa cagttagtat
    14281 tcaagctgtt ttctaacatg attaccttgc ttattttgct tcgcttgcca ataattggtc
    14341 tgcgtagatt ttttccaatt tttcttgaag agctgctttg attttttcag catattcttc
    14401 aaagtgttct tctttgttca tgtatggtgt cattacgctg gcacgcaata cagttacttt
    14461 tccggcacgg ttccattctt catctgtgaa tcctagttgg ttcacaaatt gtaatgggct
    14521 gttgccatag tctgggatag caaagtcagt atgtgaagtt aagaactcat taccgtaaat
    14581 gcttcctttc acgtatgaag aataatcata tacgtcatgg ttcaatttat tcattgcaac
    14641 taagtcatcg ttgccttttt ctttgaatac gtagtctacc atattgaaat ctggataagt
    14701 taatggatga acttcgattt ctttgtctcc tactttaaat gacaagtcat tcaagaagtt
    14761 gtagaaacga tgtgcacctt cgattgatgc acccattaat ttaccatatc ctgtgacatt
    14821 caaaggtaag acatggtgtg ctgcccaaac gctggctgct gttgcccctg cttttgaacc
    14881 ttccaagata taagccccaa gtaatgctgg gatatctgcg cctttttcaa atacatatgt
    14941 cgcaaagtaa gagataacgt ctctcatgcg gatatctttg atgacgatac caccggcaga
    15001 atatggaaca tagcccattt tatgtgggtc aatcgttaca gattctgctt cttcgattgc
    15061 tttatatgca ctgtgtactt cttctaagat ataatctttg ttttctgtaa agacattgta
    15121 tttgtaatga acatctttta aatcttcaaa tggaatgaag ttgttgtctt cgtctaagaa
    15181 aatcgcacgg ccgtatccgc cataagcagc atctacgtgt aagtagaagt aaataccgtc
    15241 tttttctaat acgcgacgca atgcaacgat tttatcgata ccgtcgattg ctccttcttc
    15301 tgttgatcct acaacaccga ctacacctag gattggtgtt ttttcagctg ctagaccacg
    15361 aacgattttt tcaagttcgt tgatgtccat gcgatagttg tggtcaactg gcactggaat
    15421 cacttggtct aaaccgatac cgatgatgtc ggcagctttt agccatgaat agtgtttagt
    15481 ttgtggaacc aaccattttc ctaatttttc taaatgtttt ccgctacgtg ctgagtgagc
    15541 tttgatttcg tcgatttttt ctgggacgct gtctaacaga ttcatgattt cttctgttga
    15601 caagttcatt aattcccaat cgctttttcc agcaactagt tcaggtgtca cttctttcat
    15661 tgcaagcggc aatgatttga tgttgcgggc ataccaaagt ccttctaagt ttgctaaaga
    15721 accatcagca acgatgtggc cccagccatc tttatagctc attaattttg caaattccat
    15781 tcctacttct tcttccattt ggcttgttgc aggagaagat tcataggcaa cgttattacc
    15841 attccatagc atagcaaaat tgtacgctag taaagatggc atcaatgttt cagagttcat
    15901 atgaccccag taacgtccgg cattatgcca aggaacggaa tgggtacgca tccgcgctga
    15961 aatttctgat agaacatcct ttgttttatt cacagtgtgt tcaaaactag cactgctttt
    16021 ttcttctggc gtaataatag gcatgtcttg aggcatgtag ttttgacgcc agcctaaatg
    16081 ttcatccacc aattcattca acaaagcttt atagatttgg ccgttctcag ctttgtcccc
    16141 aatgaatagg gcatttaggt ttagatcttt cgacaatgat tcactcatag tgaaaccctc
    16201 ctaaaaaaat atttaaattt tgtcgagccc tacattacac ctgttcttct attctgtaaa
    16261 ctaagttttg gcctgatttt taatcatatt ttaatatgta tcaattatcc gaattgttca
    16321 cacttttgaa ataattaaaa aaaacgaggg aatttacaaa tgtaaactcc ctcgcaaaga
    16381 ttgtattaac gacaaccagc gttctatttt aggatgggtt tcaaaattgg aatgttgtaa
    16441 tagtatttcc ctttttcaag gtaaaaactt actaaattct aatcaattac tttggccaaa
    16501 aagtaatttt tcttaccttt tcgaataacc acaaacttac catcgaattc atcggatgga
    16561 tttatgacaa aatttaaatc ggtaacgcgg tcaccgttaa tacttatagc tccgtttgaa
    16621 acatcttcac gtgcttgacg tttagatggt tcaatttttg tggaaacaag cagttccacg
    16681 atattttcag gtgtgcttga aatttcaacg ttcggcattt taccgaatcc ttgcgcgatt
    16741 tcttccgcat ttagttcttt aatatttcca gagaacaatg cttgcgttat tttttgcgct
    16801 tctttcaagt cttcttcact atgcacaaat cttgtaactt cttctgccaa acggcgttgt
    16861 gcttcacgtt tctcaggttc tgtctctact tttttcgcta agtcttcgat ttcttcttga
    16921 gacaagaaag taaagaattt caagtatttc actacatcgc gatcatcttg attcaaccag
    16981 aattggtaga actcaaatgg tgaagttttc ttcggatcaa gccaaacggc accgcctgca
    17041 gtttttccga atttcgttcc gtcagccttc agcatcaatg ggatcgttaa accgaacgct
    17101 tctacttctg gtccttctaa ttttcggatt aggtctaatc cagctgtgat atttccccat
    17161 tggtctgctc caccgatttg caattgcaca tcgtatgttt tatgcagatg caaaaagtcg
    17221 atagattgca gaatttggta agtaaactct gtaaatgaga ttcctacttc caaacggctg
    17281 gcaacgatat cttttgctaa catcgtgttg atgttgaagt ttttaccgta gtctctcaaa
    17341 aattcaagta aagagatttt tgacaaccag tcgtagttgt tcacaaatgt gatatttgca
    17401 tctttaccaa acaattttct catttgattg gaaagtgcgt ccacgttatg ttgcacttgt
    17461 tccatcgttt gcaacacacg ttctgttttg cggccgcttg ggtcgccgat cgttcctgtt
    17521 ccgccgccaa tcagaatata tggatgatgg cctgccaatt ggaatctttt catcatcata
    17581 aatggaatca aatgtccgat atgcatcgaa tcaccagttg gatcaacgcc gcaataaagt
    17641 gaaatgctct tttcttcaac gagctcgcga agtctttctt cgtttgtttg ctgattaatg
    17701 gcgtcgcgcc aagttaattc atcaataata ttcattttac tgacctccgt gtagtttttt
    17761 tatgaaagca ggaacctgct agcatgtgta attaattatt tcttcaggat aggataggaa
    17821 ataaaaaaag tcccttggca tataagccaa gggacgaaat ctcgcggtac cacccaattt
    17881 gtatgtctag atatccaaca tacctctcga acatttaacg ctgtcgcgtg gcaatcactg
    17941 ccaaagactc ctgaaatgta attcgcttta aagcatgtac tggtttgcag cgaccaccag
    18001 ctttctgaaa cattggcttt aacaactact tcgtttcgat cttcgtcttg ttattattaa
    18061 tatgtgtcta tcatagagcg caactttttc tttgtcaaca gaaaaaggat atttttttta
    18121 aattcctcat tttttctttt ttgaatccgc tctaattccg aacattttat tttcaattat
    18181 tgttaaaaga aataactttt tctgtatttt ttctgcaatt tatcgagaag tcactttact
    18241 ttgcctctta ttctttcttc gttacaataa ggaatgggac aagtaaaaaa atgaaaaagc
    18301 aagggacgag gtatatggaa aaaaagcaaa aaattatttt aggagccact tctgctttaa
    18361 ctatcgttat tttaattcta agtttgtttt ttgtcatccg atcatctaca aaaaaagaac
    18421 caatcattcc tgaaaaaaaa ataacagaaa aagcaaaaga accgacagat gataagcaac
    18481 aactagttac tcaagcaaaa aatctggctc aaagctacga ttatgaccaa gcgattgcgt
    18541 tattggaaaa agatagtaag aacggatcta ctgaaacaca acagcttctt caaacactaa
    18601 aaaaggagaa agaacaactg atcgactggt ctgatcctac tcagatctct catgtctttt
    18661 tccacagctt gatcgtggac ccgcaaaaag ccttccactc tcaacaggca caaggataca
    18721 aagattatat ggtgactgtt gaagaattca accgttcgat cgaacaactt tatcaaaatg
    18781 attttgtttt agttaattta aatgatttga tccaaaaaga cgaacaagga aatctttcct
    18841 ttaacgggct tgcgctacct gaaggaaaaa aaccattggt tctttcacaa gatgatgtca
    18901 gctattatga atatatggat aattccggtt ttcctagccg attggtcgta tcaaataaca
    18961 atgaaatcaa aaatgtctat aaagagaaag ataaagaaga aatcggtgac tttgacatgg
    19021 ttcctctgat cgatgccttt gtcaagaaac atcctgattt ttcttatcga ggcgcaaaag
    19081 gtaccttggc cctgacaggt tacaacggag ttttaggtta tcgaacatca aaatctcaat
    19141 atggagacaa tgaaaaaaca aaaaaagaga ttaaagaagc taaaaaagtg gcggaacagt
    19201 tgaagaaaga cggctggagc tttgcttccc atacatgggg tcacttgaat atgactcaag
    19261 cttcactaga agatgtaaaa aaagacaatg aattgtggca gcaagaagtt gcacctatcc
    19321 taggaaaaac aaatattctg atttatccat ttggtgcaga catcagcgac tggcagcctt
    19381 attcagcaga aaatcaaaaa tttgcttact tgaagagtca aggtttcgat attttctgta
    19441 atgtcgatgc ttctacacca gcttggggac aattaggtac ggatttctat cgaaatgctc
    19501 ggatcaatat cgatggcatt cgttttcaat ctgatttaga cggaaaaaat cctattcttg
    19561 atccattcat caatgtccat gatgtctatg acaaagaagc acgcgaatct gcttgatttt
    19621 acgtcattta tgaaccaaaa aagccgaact gacattttat cgtcagtttc ggctttttta
    19681 tgctttattt cttcttcggt gcgattccct tgatcaggac ttctgtccat tctgctgtat
    19741 atggaagcag ttttgcgtat atctccggct tagaaattcc ttctaccatt gcttgaaaat
    19801 agaggatcaa gaactcatcc gaatatttca aatccacttt tccttctttc cgccctcgat
    19861 ggaaaagatc aagcatgata ctgaaacttt cttgcgtata cgcatccatc gcgtcagaaa
    19921 attctttttt ttcttttttt gtatagtatg tcatcaaatc gatataaaat tgtttgttca
    19981 ctcgattgag ataacggatt ttgttttcac tcatggcaat cagtgtttct tcaaatggaa
    20041 gattttccgc aatcaacgct ttcgcttctt gccctaaatc attcataaat gcaaaaaata
    20101 cttcataaat cagcccttcc ttgctgccaa aatatttaaa aatcgtcgct ttacttacct
    20161 gagcgttctc agctacctta tccattgtca ctccagcggt tcctatgtct gtgttcatca
    20221 agtcaaaagc tgcttgtaaa atctctttct ttttctcttg tgctctcttt tcaaaaccgt
    20281 tcatttgtag agcctcccgt aattttaaac ttttataata tatatagttc aaatttattc
    20341 tgaggtttat tataactatc tattgagaaa gtatcaagct agcaattcct tgtttatgaa
    20401 ttcattgaca
//
LOCUS       DAXLPC010000048        20209 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.048, whole genome shotgun sequence.
ACCESSION   DAXLPC010000048 DAXLPC010000000
VERSION     DAXLPC010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.048"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            89..1720
                     /locus_tag="ACF3UE_001651"
     CDS             89..1720
                     /locus_tag="ACF3UE_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFD3635056.1"
                     /translation="MFKKYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(1782..2423)
                     /locus_tag="ACF3UE_001652"
     CDS             complement(1782..2423)
                     /locus_tag="ACF3UE_001652"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFD3635057.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    2609..2685
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            2705..3013
                     /gene="rplU"
                     /locus_tag="ACF3UE_001653"
     CDS             2705..3013
                     /gene="rplU"
                     /locus_tag="ACF3UE_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFD3635058.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            3040..3384
                     /locus_tag="ACF3UE_001654"
     CDS             3040..3384
                     /locus_tag="ACF3UE_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFD3635059.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            3397..3690
                     /gene="rpmA"
                     /locus_tag="ACF3UE_001655"
     CDS             3397..3690
                     /gene="rpmA"
                     /locus_tag="ACF3UE_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFD3635060.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            4124..6931
                     /locus_tag="ACF3UE_001656"
     CDS             4124..6931
                     /locus_tag="ACF3UE_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3635061.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            7122..7613
                     /locus_tag="ACF3UE_001657"
     CDS             7122..7613
                     /locus_tag="ACF3UE_001657"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFD3635062.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            7716..8705
                     /locus_tag="ACF3UE_001658"
     CDS             7716..8705
                     /locus_tag="ACF3UE_001658"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFD3635063.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            8738..9541
                     /locus_tag="ACF3UE_001659"
     CDS             8738..9541
                     /locus_tag="ACF3UE_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFD3635064.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            9562..10476
                     /locus_tag="ACF3UE_001660"
     CDS             9562..10476
                     /locus_tag="ACF3UE_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3635065.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            10559..10933
                     /locus_tag="ACF3UE_001661"
     CDS             10559..10933
                     /locus_tag="ACF3UE_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFD3635066.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            11072..11317
                     /locus_tag="ACF3UE_001662"
     CDS             11072..11317
                     /locus_tag="ACF3UE_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3635067.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            11489..12553
                     /locus_tag="ACF3UE_001663"
     CDS             11489..12553
                     /locus_tag="ACF3UE_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFD3635068.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            12799..13224
                     /locus_tag="ACF3UE_001664"
     CDS             12799..13224
                     /locus_tag="ACF3UE_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3635069.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            13217..13666
                     /gene="nusB"
                     /locus_tag="ACF3UE_001665"
     CDS             13217..13666
                     /gene="nusB"
                     /locus_tag="ACF3UE_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFD3635070.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            13763..14617
                     /locus_tag="ACF3UE_001666"
     CDS             13763..14617
                     /locus_tag="ACF3UE_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFD3635071.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            14618..15955
                     /gene="xseA"
                     /locus_tag="ACF3UE_001667"
     CDS             14618..15955
                     /gene="xseA"
                     /locus_tag="ACF3UE_001667"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFD3635072.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            15960..16184
                     /locus_tag="ACF3UE_001668"
     CDS             15960..16184
                     /locus_tag="ACF3UE_001668"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFD3635073.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            16186..17076
                     /locus_tag="ACF3UE_001669"
     CDS             16186..17076
                     /locus_tag="ACF3UE_001669"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFD3635074.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            17085..17903
                     /locus_tag="ACF3UE_001670"
     CDS             17085..17903
                     /locus_tag="ACF3UE_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFD3635075.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            18010..18459
                     /locus_tag="ACF3UE_001671"
     CDS             18010..18459
                     /locus_tag="ACF3UE_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFD3635076.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            18477..20159
                     /gene="recN"
                     /locus_tag="ACF3UE_001672"
     CDS             18477..20159
                     /gene="recN"
                     /locus_tag="ACF3UE_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFD3635077.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
BASE COUNT         6547 a         3392 c         4533 g         5737 t
ORIGIN      
        1 ctttgtgaaa aatattactt tatctcatga aatatgatat tctaatgaat ggtattttag
       61 aaaatttcat gaaaaaggag ttagataggt gttcaaaaaa tatgtttcct cactaaaaaa
      121 agaattttca ggttatgatc tttcaagatt tcagaaagat cttttggctg ggatcacagt
      181 agctgctgta gcattgcctt tagccttggc ttttggggta tcaagcggag ctgatgcggc
      241 cgcaggtttg attacggcta tcattgccgg tatcgttatt ggcggtttat caggcggttt
      301 ttatcaaata tcaggtccga caggtgcgat ggcagctatc ttgatgtcta ttgcggcaac
      361 aaagggaatg caaggtgtat tgcttgctac ttttttagcg ggtctatttt tacttgcagc
      421 aggacttttc cgattaggaa cactgacttc ttttatccca gcacccgtaa ttacggggtt
      481 tacttcaggt attgctatca ttattgcatt aggtcagatc gataatttat ttggtgttca
      541 ctcggaaggt acaaacgtta ttgaaaaact aagtagttat caaacgatag gatttccgat
      601 aaacacagcc tctttgatca tgggagggct agtcatttta gggatgttta tctatccaaa
      661 aaaatgggcg aaacgaatgc ctagttcgct gctggctatc attttggcaa cagcagttat
      721 gctattgttc catttaccag tagcaactgt gggtaagatt ccacaaacat tgatcagtag
      781 taatcgtttg aatatgggag attttagctt ttctgccttg caacaagtgg cagttccagc
      841 tattagcatt gctttattag gaatgattga aagcttgcta tgtggtgctt cggctggccg
      901 aatggcaaat aagcccttag atagcaatca agaattaatg gcgcaaggaa ttggaaatct
      961 gttgcttcct ttctttggcg ggattcctgc tactgcggcc atcgcccgta caagcgtggc
     1021 catcaaatct ggtgcacaaa ctagattagc tggtatgata catgcagttg tcttactgct
     1081 ctccatgctt gtttttgcgc cagtgatgtc acagattcca atgccagcac ttgcaggtgt
     1141 tttgattgtg acggcttggc gtatgaatga atgggaaacg atcaaggagc tatttactaa
     1201 taaatattgg tcagcagttc tattgtttat ccttacgatg atttgtacag ttatctttga
     1261 tttaagtatt gctatcgtga tcggggtgat cggcggctgt gtattttttg ttgtcaaaag
     1321 cgctgctatc acgatttcat tagaaacgat cgattggcaa agaatggggc tgccagaaac
     1381 ggaaaagctg aataactgga cagtagtgta tattagtggt ccactgtttt ttatgtcttc
     1441 agaaaaactc aaaaataaat tggaagaact aaatcatcac gatggtgtca ttttctccat
     1501 gcgaggcgta ccaagtattg atttgacggc acgtgcagtt tttgatgaat ttcaagaaaa
     1561 agcagagcaa agaggacaaa cgattatcta tacttccttg cagccagaag tagaaaaaca
     1621 actttctcac ttgtgggaac atacattcac gcatcaacat caaacagttg ctcatgcgtt
     1681 gacagcttta catgcgaaat atactgcaat tagccattaa aacaatgaaa aagaacagac
     1741 aagactgtaa actgaagatt ttatggtctt gtctgttctt tttaatattg ctgtaaaagt
     1801 gaagctagta cttgccagtc ttgatggata acaggtacaa gggagcgatt gtagaaaata
     1861 gctgctggat gaaaaagtgg aagaattcga tagttttttt ctgaccattc gtaggcatcc
     1921 ttttgttctg ttaattgtaa gacaggccct gtatagagtt gaccatgatt tttggtaacc
     1981 gtatattctt tgccaagtaa acgttgaaga ccaatgtttc caagtgtcgc aattaatttt
     2041 ggctggacct tcatcagttc gtaatccaat attggtgcat gcgcaaatac ttcggaacga
     2101 gtaggtgtcc gatttggata aacagtttct gactgttgtg tccgtttatt gatccgatga
     2161 gtcacgcgat acgggcggct ccttacagca ctggtgatat acacctcttc tcgtgttaag
     2221 ccagttgaag aaagtgcctg catcaattct tttccagctt gaccgctaaa aggaacatgc
     2281 gtatcaatct ctgttttccc tggggcttct cccacgagca tcagtttagg atgaagaggt
     2341 ccttgcccag cgataaatcc ttctacagga cggccgttca ttcttaaaga agcttcttgt
     2401 atcagttctt ttgggtattc catttatgct cctccttttt cttttattat aagaataaaa
     2461 gaaacacaat gcgactattt tatttggtag aactgtgagg atagaaaagc agaagtattg
     2521 cttgaatttt tgttttactt tttgatttta aatttagttg actaacggtt gctgttctgg
     2581 taagctagta ctgttgtaat tgtggactcc acagctacaa ccgctcagaa caagtaataa
     2641 gcacagcata tgctgtcact tcggatggcg agtctaagta tatgagaagg aggtgcttta
     2701 tagcatgtac gcaattatta aaactggtgg taaacaagta aaagttgaag tgggacaagc
     2761 aatctatgtt gaaaaacttg acgttgaagc aggagaaaaa gttgtttttg acgaagttat
     2821 cttagtaggc ggagaatcta caaaagtagg cgctccaact gttgcaggtg caactgttga
     2881 aggtactgtt gaaaaacacg gcaaacaaaa gaaagtcgtt actttcaaat acaaacctaa
     2941 aaaacattca caccgtaaac aaggtcatcg tcaaccatat acaaaagtgg ttatcgacgc
     3001 gatcaacgct taatagcgtt tgagaaagaa ggcctatata tgatcaaagg aacatttaag
     3061 cgaaatgacg caggtcagat cgtttcattc actttgaccg ggcatgctga tgctggtcct
     3121 tatggaagtg atatcgtttg tgcgggtgtt tctgcgttag cgatcagcac tgtcaacggg
     3181 attgcctcat tagccggttt tgagccgatt gttgaaatga atgaagaaga aggcggttat
     3241 ctttataccg aagtcacttc aggaatgaca caagaacaaa acaatattgc tgagattcta
     3301 ttagaaaatc ttttattagg attacaatcg atagaagctg aaaactcaga atatatccaa
     3361 attaaaacaa ttaatgataa ataggaggtg cagaccatgt tgttatctat gaatctacaa
     3421 ttatttgccc acaaaaaagg tggcggttct acatctaacg gccgtgactc agaatcaaaa
     3481 cgtctaggtg ctaaacgtgc tgatggacaa acagttacag gtggatcaat tctttaccgt
     3541 caacgcggta caaaaatcta tccaggtgta aacgtgggta tcggtggaga cgacacttta
     3601 tttgcaaaag ttgatggcgt agtacgtttc gaacgtaaag gccgtaacaa aaaacaagtg
     3661 tctgtttatc cagtagctca agaagcttaa ttgaatctta tgattaaaga ggttgtgaca
     3721 agacttttgt cacagccttt tttgtttata aaaataaaag ttgtagtgga ggctacgaag
     3781 tttactttgt ctttttacac ttaatatttt tttgccaatt tggaatcagg atgttttgat
     3841 aactatcgtt ttcaattgat ggaagctata ttgtttgcta tcagtgaaat aattatatgg
     3901 taaacagtgt tctttttctt gtttccatta taaaaatcgt atcgggattt ttcgttcttt
     3961 taaattgaac atttctatct atccgcgtgt tatcaacaaa acaaaatcag gtaaatagtt
     4021 gacgaaacag aaataaatac atagtattat gttttgaagc ctaagtacaa tagtctatag
     4081 aaaaggagcg ataccattgg caaaacgcat tgaccgaatt tatatgtatg tcaaagaaaa
     4141 aaccgctcat ttaacaaagg cagaatatga tcaaggagta acaacacagg aaattgctga
     4201 agtgttaggg attcagcgaa caaatagcag taaagatctg aatcagctag tgcgcgaagg
     4261 aaaactgata aagacagacg gacgaccagt acgttacata tatcaaacac tcgttacgca
     4321 cgtaaagcca gttacaaaac atgtagtcag ttacaaagaa acgccggtct ctgaagaaaa
     4381 aaatacactc caaatagata ctaaggatat ctttgcaaaa atcattggag ctaacggcag
     4441 catgaaaaat tcagtggaac aggcaaaagc tgcgattttg tatccgccaa gaggattaaa
     4501 ttgtttgatt acaggaccta ccggatcagg aaagacttat tttgcacacg cgatgtatca
     4561 ttttgcaaaa gcgcatcatg taatagatga ggaaacggaa ctgattgttt tcaattgtgc
     4621 tgattatgcc aataaccctg agcttttgat gagtcattta tttgggtacg caaaaggtgc
     4681 ttttacaggc gcagatgaag aaaaaatggg gattatcgat caagcggatg gcggtatgct
     4741 gtttttggat gagattcacc ggttgccgcc tgaaggtcaa gaaatgatct tttactttat
     4801 ggatcatgga acttacagtc gtcttgggga aacaacgaaa tcccatgaag caaatgtacg
     4861 gatcgtaggt gcgaccacag aagacccagg ttcttctcta ttagaaactt ttgttcggcg
     4921 tatcccaatc aatatcaaac ttccggcttt tgaaaaacgt cctgcaaatg agaaagtcga
     4981 tttagtaaaa atcatgattg cccacgaagc aaaccgcacg cagcgaaaga tttctttgac
     5041 agaagatgta gcaaaagcat tgatcggcag tgtgacctat ggaaatatag gacaattgaa
     5101 gtcaaatatc cagttagtat gtgcacgagg atttctaaat catatgcaat cacccgaaat
     5161 ctcgatcaca atcgatgatt tgacagaagg gattcgtagc ggattgattc aattagcaag
     5221 caaccgcagt gcaatggcag agctttctaa aatattggag ccaaagataa ctgtagcacc
     5281 aaatgatacg atcatgaaaa tccaatcgga ctcctatgag ttaccttata atctatatga
     5341 tatcatcgga gataaagcag ctttactgaa gtcggatggt ttggatcaag aagcaatcaa
     5401 tcatttcatt tctacagata tcaacatcca tctgaagtct ttctataaag accatggttt
     5461 ttcttttaat gcagacagca aattagcaga atttgtagat ccgaaaatca tagaagtgac
     5521 caatcagatt tatgtaatgg tcaaaagatc tttaccatat gagtttcagc aaaactttat
     5581 ttatgctatg agcttgcata tcagttcttt tttgaaaaaa atcaacttag gagaagaacg
     5641 gcatacgaat gataacatcc gtgagatggc ttttgatttt ccagatgaat atgctgttgc
     5701 gaaagaagtg cgtagttata tcgaaacgta ttttcaagtg gagattccag aaagtgaaga
     5761 ctattacttg accgttctac tcgtctcgtt acgggcaaat caagcaagcg gcagaatcgg
     5821 tgtagtcgtt gcagctcacg gaaacagcac agcaagcagt atggtccaag ttgtccaaca
     5881 gttgttagat gcagagaacg tacgagcagt agacatgcct ttggatatgg atccgaaaac
     5941 agcattggac cgaattgaac gcaatgtaca agaagtagat gaaggaagcg gggtcatact
     6001 cttagtagat atggggtccc ttgcgtcgtt taattcgcaa attcaaagag acactggaat
     6061 tccagtacgt actgttgata tggtaacaac ttctctagtt ttggaaactg tacgaaaggt
     6121 ctcagtatta gggacagatc tagatatgtt gcatgaatca ttgaaaaatt ttcgaggtta
     6181 cgcagaaata tcttctgtag aatctgttca ggaagcaaaa cctattcata agaaaaaagc
     6241 tgttttggct atctgcgcat ctggcgaagg tacagcacaa agaatcaaag aattgatcga
     6301 acgagcggta aacaagcgtc aagaaacaga attagaagtt ctagctttgt cgattgtgga
     6361 agtgaaagaa gaactgccag ttatccaaaa agaatatcag atcatagcta ctactgggat
     6421 tactgatttg aatatccaag ccccatttat tcctttagaa cgttttattg atcaaaatat
     6481 cgaagtcatt ttggatcagt tgctgatgga atcagaattg gaggaaactg aattcatctc
     6541 cctagatgaa gagtcagcta aaaatacgtg tgttgagttt atctctgata acttcatctt
     6601 tattaatggt agtaagttaa tcgatccaat gtggcaattt tctacacaaa tctctcagac
     6661 gacgggaatc ggcgatgaag aatatggatt caaaatcaac ctagtgatgc acacagcagg
     6721 aatgatcgaa cgtattattc ggaatgaacc attgactgtg gaagaaaacg aattgacaaa
     6781 tacaacgaat gatcctcttt atagccaatt ggcagcctca gttgttctgt tggaagatca
     6841 gataaaagta aaagtgccga tagaagaaat gtattatctg ctacgtctag tccataatca
     6901 gttagataaa aaagaataca ctgtgccatg aatacacaaa aacgatacac ttttatagtg
     6961 tatcgttttt gtgtattggt taagaatcct ttaaattcaa ttagtgtatc gtaaaaaagt
     7021 tggcacgctt tttgcttata gtagtgtgtg ctaggaggtg gttgttcaca cagaaatgat
     7081 aggggtttct gtgaagtagt gaggaagaag gagttttgca gatggatatt cgattggcac
     7141 gtatagatga tcgtttaatc cacgggcaag tcgcaacagt ttggtcgaag caaacaggtg
     7201 ttgaacgtat cattgtgatc agcgatgtag tcgctcaaga taaattgaga aagtttctac
     7261 taaaagaagc tgcaccgccg gggatcacag caaatgtaat aaccgtgcag aaaatgattc
     7321 aaatctatca tagtggatta ttatcacgag caaaagtgat gcttttattc accaatcccc
     7381 aagatgttga agcggttgtc cgctgcggtg tacagttgaa gtcgttgaat atcggcggta
     7441 tgagttttac tgaaggcaaa tcaatgatta ccaattttgt ttcagtaaat caacaagata
     7501 ttgattcctt tcgttacttg aacagtcaag aagtggagtt agagattcga aaagtacctg
     7561 ctgacaggaa aatccttttg atggaactac tagcgaaaat caaaaaggtg tagcaagaat
     7621 ggttgttgga aaaggtcaaa taattctgtt gtaatggtta gcaattatta atatttttga
     7681 atttgttaca acaaaagtaa ataggaggta taaatatggt agggattatc ctagcaagtc
     7741 atggacaatt tgctgaagga atcttacaat ccggttcaat gatctttggc gaacaagaaa
     7801 acgtcaaagc cgtgattttg aaaccaagtg aaggtccaga tgacttgaga gccaaattgg
     7861 aagaagcggt tgcttctttt gataatcaag acgaagtgtt attcttagtt gatttatggg
     7921 gcggaacacc gttcaatcaa tcaaacacat tattcgaaga gcacaaagat aaatgggcaa
     7981 tcgtcagcgg tttgaattta ccaatgttga ttgaagccta cgcatcacgc ttttcaatgg
     8041 aatctgctca tgaaattgca gcacacatca ttgaaacagc aaaagacggt gtaaaagtaa
     8101 aaccggaaga attagaaccg gcagaagcac cgaaagcagc agttgaagac gcacaaccta
     8161 aaggagcact tccagaagga actgtggtcg gagacggaaa aatcaaatat gtattagcac
     8221 gtgttgactc acgtctgtta catggacaag ttgcgacagc ttggacaaaa gcagtgcaac
     8281 caaaccgtat tatcgttgtt tcagatgcag tatcaaagga tgatctgcgt aagagactaa
     8341 tcgaacaagc tgctcctcca ggtgtaaaag caaatgttat tcctattagc aaaatgatcg
     8401 aagtagcaaa agaccctcgt tttggaaata ccaaagcatt gcttttattt gaaaatcctg
     8461 aagacgtatt gacagctgtt gaaggtggcg tagacatcaa agaattaaat gttgggtcaa
     8521 tggcgcattc ggtcggtaaa gtcgttgtaa gtaaagtatt gtctatggga caagaagacg
     8581 ttgaagcgtt tgagaagctt gaacaaaaag gtgtgaaatt cgatgtacgt aaagtaccta
     8641 atgattcacg cgataacatg gatgatattt tgaaaaaagc aaaagctgaa ttagcaaaag
     8701 cgtaataaat aatattaaaa tttataggag gcttatcatg tctattattt caataatttt
     8761 agtcgtatta gttgcctttc tagctggtat ggaaggtatt cttgatgaat ttcaatttca
     8821 tcaaccacta gtggcatgta cattgatcgg tttagttacc ggtaacctcg aagctggtat
     8881 cgtacttggc ggtacgcttc agatgatcgc tttaggttgg gcaaatatcg gtgccgctgt
     8941 agcaccagat gctgcattag catcagtagc atcagcaatt attttagttt taggtggaca
     9001 aggtgttaaa ggtgttcctt ctgcgatcgc gattgccgtt cctttggctg ttgcagggtt
     9061 gttcttaaca atgatcgtac gtacaatcgc tgttccaatc gttcatttga tggatgcggc
     9121 tgctgaagaa ggaaacatcc gtaaggttga aatgtggcac atcattgctg tatgtttaca
     9181 aggggttcgt atcgcggtcc cagcagcagc gttgctattt atcccagcac aaactgtgca
     9241 atcattcctt gaatcaatgc cagcatggtt aacagatggt atggctatcg gtgggggaat
     9301 ggtcgtagct gtaggttacg ctttggtaat caacatgatg gctacaaaag aagtatggcc
     9361 attcttcgtt attggtttcg ttgtagctgc aatttctcaa ttaacattga ttgctctagg
     9421 tgctttaggt gttgcattag ctcttattta cttgaacctt tctaaaatgg gtggttcatc
     9481 aaataatgga ggcggaagca actctggtga ccctttaggc gacattttga atgactatta
     9541 atcttgaagg aggaaaataa aatggcagaa gaaaaaatca aattatcaaa aaaagatcgt
     9601 ttagctgttg cgtggcgctc taccttcatt caaggttcat ggaactacga acgtatgcaa
     9661 aacggtggct gggcattttc tatgattcca gcaatcaaaa aattatacaa aacaaaagaa
     9721 gaacgttctg cagcattaaa acgtcacttg gaattcttta atacacaccc atacattgct
     9781 tctccaattt taggggttac attggctctg gaagaagaac gtgcgaatgg cgcgcctgtt
     9841 gatgatgtag cgattcaagg ggttaaagta ggtatgatgg gtcctttagc tggtgttggt
     9901 gacccagtgt tctggtttac agtacgtcca atgctaggtg cactaggtgc ttcattagct
     9961 atgggaggaa atatccttgg accaatcatc ttcttcttag gttggaacat tattcgttgg
    10021 gcattcatgt ggtatacaca agaatttggc tacaaagctg gttctaaaat tactgatgac
    10081 ctttctggcg gattgttaca agacgtaaca aaaggtgctt caattttagg gatgttcgta
    10141 ttagctgccc ttgtacaaag atgggtatca atcaaattct taccagttgt atcaactgta
    10201 aaattagata aaggtgctta catcgaatgg gataaattgc cttcaggtgg tgaaggaatc
    10261 aagagtgcat ttgaacaagt taataatggc ttagcccttt ctcctgaaaa ggtaacaaca
    10321 ttacaagaca acttagacca attgattcct ggtttagctg cattaggatt aacattgtta
    10381 tgtatgtggt tgcttaagaa aaaggtttct ccaatcgtta tcatccttgg tttattcgta
    10441 gtcggtgttg ttggacacgt catcggactt ttataatcca taaaaatata gctcgggcgt
    10501 tgtcccgagc tttttttata tagtatactg ttcataaaca aatatctgga gggagaaaat
    10561 ggttcaatca atcaatacaa aagtagactt ggtaattgat gctacttcgt ttacgggtct
    10621 gacagattac gggcaaatca tgataggtga taatggtttt gagttttacc atgcgcgaga
    10681 tagacgcaaa tatatccaaa ttccatggga agaagtggat tatgtactag catcagtcat
    10741 gctaaaggga aaatggattc ctcgatatgc cattcaaacg aaaaaaaatg gtacatacac
    10801 attttcttcc aaagaaccta aaaaagtgct tcgtgcgatc agagaatatg tagatgaaga
    10861 tagaatggta caatcattga gtttctttga tgtagtgaaa cgtggtattc gtagtatgtt
    10921 taaacgcaag taaaaaataa agaaaacttc taagaggagg ttttctttat ttttttactt
    10981 tgcagaagaa aatatgaaat agcaaaacca attatttgtc ccctttaaat cccatatgct
    11041 aaaattgatt agcaaagaag gaggttatat tatgagttgg ttatggacat tgattgttgg
    11101 agccgtgatc ggagcaattg caggtgcgat caccagtaaa ggaaattcga tgggctgtgt
    11161 aacgaatatc attgctggac tagtcggttc aagtattgga caagcgattt tcggcgaatg
    11221 gggaccaaaa gctgcaggta tggcacttat tccatctatt ttaggcgcag tgattttggt
    11281 agcagttgtc tcatttttct ttggaaaacg atcataagtt tttacaaaat agtaaactaa
    11341 aaggagttgc agcgagactg tgactccttt ttggctttat ttatttaaaa taaaaagaag
    11401 ttttccggaa atttttattt aactgtcgtg tacgaagaaa agtttgctat aatggaaaaa
    11461 agcgtgcaaa gaaagaggga gtttcattat gatgctacgt gtagaaaaat tgcgcaaaaa
    11521 aatgcaagaa gaaaatttgg attcattttt ggttaccagt ccgtacaatc ttcgttactt
    11581 aacgaacttt acaggtacga caggattagc tgttattact ttggaaaaag cattttttat
    11641 tactgatttt cgttataccg agcaggcggc agcgcaggct caagggtttg aaattattaa
    11701 aaatgtcgga cctatttttg atgaggtagc aaacttagta cgcaaagaag aactgcactc
    11761 attagctttt gaggaaacaa cagtctcatt tttagaatat tcggttttag aagaaatcat
    11821 cgatgcggaa ttagtacctg tttcacagat gatcgaagaa ctcagagaag tgaaagatga
    11881 agaagaaatc gctattatcg aaaaagcatg tcatattgcg gatatggcat atgatcacat
    11941 cctgaaaatg atccaaccgg gcatgactga gattgaagtc gcaaatcaac tagactttta
    12001 tatgcgttct cttggcgctt caggtgtttc ttttgatacg atcgttgcta gcggattgcg
    12061 ttcggctatg ccgcatggtg tagcaagcaa aaaaatcatc gaacaaggtg acttgatcac
    12121 attggacttt ggttgctatt acgaagggta cgtttccgat atgacacgta cattcgctat
    12181 tggtgatcct ggggaaaaat taaaagaaat ttatcaaata gtcttagatg ctcaattagc
    12241 agttattgat gctgcaaaac caggaatgac tggtgtccaa ttagatgcag ttgctagaga
    12301 ttatatttca aaacatggtt acggggaagc atttggacat tctacaggac atgggatcgg
    12361 tttagagatc cacgaaggac caaacgtttc ttctcgtgca gaaaagcaat ttgtaccagg
    12421 aaatgtgatc actgatgaac cagggatcta cttaccagga atcggtggag tacgtattga
    12481 ggatgacttg ttgatcacag aagatggaaa tcgtgtgttg actcgttcac caaaagaatt
    12541 gatcatctta tagtttcatc aatagaagaa gtaagcgtaa aaatcagtgt tcacagactt
    12601 tgttatagaa aatcactcga tttaatgata cactatagaa gaacttttaa gctgtaagag
    12661 ataataaagt tgggtgtttt ctccaattca tagcagtttg cagctgatcg gcggcagttt
    12721 tcttaccacg tgatcactat gccgcatcat agagaattcg gatgtatctc gtgcttaggc
    12781 aaagggagga ataaataaat ggcagatgaa aaaaatttga ttttaaacgc aaaccaagat
    12841 ttaggagaga tcgtgatcgc tcctgaagtc atcgaagtaa ttatcgggat tgcagcttct
    12901 aaagtagaag gcgtatacgg aatgcgcgga acttttgcca gcaatgtcac tgaattatta
    12961 ggacgtgcag ctcacggaaa aggtgtttac ttagcaaacg aggaagatgg cttgaaagta
    13021 gatctttact gttatctaga atatggtgtt tcagttccta aagtagcaat ggaaatgcag
    13081 gaacgggtca gccagcaagt ccttttcatg acggatatcg atttatctga agtcaatatc
    13141 catgtagtag ctgttgttcc tgaaaaatta gaacaaccaa caatcgaaga actttttgaa
    13201 gacgaagagg aagagaatga ataaagaatt atcaagacac gagattcggg aaatggcatt
    13261 gcaggcttta tttccattag acttcaatgc agacctaaca aaagaagatg cgattttcaa
    13321 cgcaatcgaa ttagaccacc gcgacatgat caacgaagat gaatcagagt ttgttcctgt
    13381 ttatcttgat acgctagttg gcggtgtctg tgcaaaaaaa gatgaattgg ataaagtgat
    13441 tgaaaaacat ttaaaaaaca attggcacat caatcggatc tcaaaaatgg atttggtgat
    13501 cttgcgtatc gcgatttttg aaatgactta tgtgacagat gtaccagcgg ctgttgcttt
    13561 aaatgaagca atcgagttgg caaaaacatt tagtgatgac cgttcacgta aattcgtcaa
    13621 cggtgtttta tccaatgtat tgaaagaatt agaagctggg gcgtaagtcc tagctttttt
    13681 ctatgaatca tcataaacct gttataaatc gggaaaattc tatggtagaa tgaaaacaca
    13741 aaaaatatct gggagtggtt agatggcaga attgattaac ggaaaagaat tagctgaaaa
    13801 aatgcaggca gagattgctg aaaaaatcca aaaattgaaa gataatggta tccatcccgg
    13861 attagtcgtt ttattggtag gggaaaatcc agccagccaa atctatgtaa gaaataaaga
    13921 acgtgtagca aaagaaatcg gaatccattc attggtagag cgttatcctg agacgatttc
    13981 tgaagacgaa ctacttgcag aaattgaaaa atacaatcaa gatcctagtt ttcatggtat
    14041 attggtccaa ttaccattgc caaagcatat agatgaagaa aagatcctgt tagctatccg
    14101 ccctgaaaaa gacgtagacg gttttcatcc gatgaattta ggcagactcc ttgcgggtaa
    14161 accggacaag attccttgta ctccatacgg catcatgaaa atgtttgaag cttattctat
    14221 cgatccggcg ggtaaacgag cagtagttat cggacgaagc aatatcgtcg gtaaaccgat
    14281 ggctcagcta ctcttgatgg cagatgcaac tgttactgtt gctcattcta aaaccgaaaa
    14341 tctggctgaa ctggcacaag aagcagatat tttagtcgta gcaataggac gtggacattt
    14401 tgtcacaaaa gaattcgtaa aaccaggtgc tgtagtgata gatgtaggga tgaatcgtga
    14461 tgctaacggt aagctgatcg gtgatgtgaa atttgatgaa gtggagccta ttgcaggctg
    14521 gatcactcct gtgccaaagg gtgtagggcc aatgactatc acgatgctga tgtatcaaac
    14581 cgtaaaatct gccgaagctt ttggagcagg tgaatagatg gcacaagaat atttaactgt
    14641 cactacatta acgaagtatt tgaaaagaaa atttgatgcc gatccttatt tagaacgcgt
    14701 atatttaaca ggcgaaatat cgaatttccg tttacgtgcc aatgcccatc aatatttcag
    14761 cttaaaagat gaccatgcaa aaatatctgc tattatgttc aaaggagcat tccaaaaatt
    14821 acgattccag ccaaaagaag gaatgaaagt ccttgtcgtt gggcgtattt cattatatga
    14881 agcgggaggt tcttatcaaa tctatgtaga gcacatggag cctgatggaa taggtgcttt
    14941 atatcaagaa ttggaagaac gaaaagaaaa gctgatgaag gaaggccttt ttcaagggcc
    15001 taaaaaaatg ctgccacgtt tcccaaagcg aatcgcggtc cttaccagtc caagcggagc
    15061 ggttatccgc gatatcatca cgacggtgaa aagaagatat ccaattgtcc aattggtttt
    15121 gttcccaaca gttgtacaag gaaaccaagc agcggacaat gttgtcagga atatccagag
    15181 agtagaagag atgggcaatt tcgatacaat gatcatcggt cgtgggggtg gttcgattga
    15241 ggatttatgg ccgtttaatg aagagcgggt tgctcgggcg atttatcaag ctaatacgcc
    15301 ggtgatttca tctgtaggac atgaaacaga taccacgatc gctgatttag tagcagatgt
    15361 tcgggctgcc actccaacag cagctgcaga attagctgtt cctgttttgt cagaagagtt
    15421 gatgcgcatt caagaacggc aagctagatt gcagcaggcg tttgtacgcc agatccagcg
    15481 caaacaagaa cggttcgagc gtgctcgacg ttcctatgta tttcggcagc ctgaaagatt
    15541 gtatgaaggt cagaccatca aattagacca gttgaaacag cgattatatc aagctacaca
    15601 gcaaatttat catgcgaaag aaaaacaaac gatcgcatta agccaccaat tggaacaagt
    15661 ggctccgctt tatcgagtta aagcagctcg ccaagaaact gcttatctag aaaaacgctt
    15721 agaagagaaa atccaacaat atatgaaaca acagcagcag cgttttgctc aagctgttca
    15781 atctcttgat ttgttgagtc cattgaaaat catgggaaga ggctacagct atacgacgtt
    15841 aaatgatcaa gtagtaaaaa gtgtcaccga gattcatcaa ggggatttgc tgacgatcca
    15901 ttatcaagat ggaatcgtta aaggacaagt acaagagata gacaaaggag aataaaaata
    15961 tggaaaatcc aacttttgaa gagtcactgc aagaattaga aaaaattgtc atgcagttag
    16021 aacaaggaga cgttccatta gaatcagctc tagattcgtt taaacgagga atggaattaa
    16081 gcaaacattg ccaagataca ttagctaaag cagaagagac cttgacgaaa atgatgacag
    16141 aatcaaatga agaagttgat tttgacggaa acgaggaaag ctgagatgag attaactgac
    16201 ttttcagcta ttcatctacc tgctgtagaa aaagaaatct tgtctttttt agatgagcat
    16261 acaacggata gaggactcta tgatgcgatg agttattcag tgaaagcagg cgggaaaaga
    16321 atacgtccct tattactttt aacggccgtt gcttcctttg atgagcctat tgatgttccc
    16381 gtctatcaag tagcagctgc tttagaaatg gtgcatacgt attccttgat ccacgatgat
    16441 ttgcctgcga tggacaatga tgatcttcgt agaggaaaac ctaccaatca taaagtattc
    16501 ggcgaagcat tagctatatt ggccggagat ggtttgctta caggagcatt ccagctaatc
    16561 agtatggcac acttaggtaa ttctcctaag cttctgctgc ttcagcaatt agctgtttgt
    16621 gcgggatcac aaggtatggt tgctgggcaa gctgcagata tcgagggcga atcgaaaaag
    16681 ctttctttag aagaattagc atttattcat gaaagaaaga cagggcattt gattcgttat
    16741 gccttgctgg ctggtggcat attagcgaag caacctgaag aaatcttatt gctacttcaa
    16801 cgattagccg aacatttagg tttagctttt cagataagag atgatctact cgatgtgatt
    16861 ggtacaacga aaacattagg gaaaacagct ggtaaagatg aacgtatgga aaaaaatact
    16921 tacccgcgtt tattaggcct agaaaagaca cgtgaggcgt tggagattga gctgttatcc
    16981 gccaacaaga tcatagacaa attagaagag gacgtttttt cttttgatgg cgggctgatg
    17041 cgccagatga tcaagcaatt tgatgtggag aaatgaggga aagaatggaa aaagaacgcg
    17101 tagatgtatt agcggtcaaa caaggattat ttgaaacaag agaacaagcc aaacgttcag
    17161 tgatggctgg tttgatttac aacgaaaaaa acgagcggtt tgataaaccg ggagaaaaaa
    17221 ttccagtgag tagtgaatta agagtcaaag gtaaaaaact tccttatgtt tctcgagggg
    17281 gattaaaatt agaaaaagca ctcaaagcat ttgatctatc tgttgaagga aaaacattgt
    17341 tagatattgg tgcatccact ggcggattta ctgatgcagc tttgcaaaat ggcgcaaaaa
    17401 tgagttatgc tttagacgtt ggctacaatc agctagcttg gaaaataaga caagatccta
    17461 gagtcgtcgt aatggaaaga gtgaattttc gttatgcaaa acccgaagac tttaccttag
    17521 gaattccaga agttgctgtt atcgatgttt cttttatttc actaaaactg atgctgcctc
    17581 cattacatgc tattttaaaa gaagagggag aagtgattgc tttaatcaaa ccccaattcg
    17641 aagcaggcag agaagctgta gggaaaaacg gaattgttcg tgaccctcag acccatcaaa
    17701 aagttttaga agacattttg tcatttgcgg cacaaggtgg atatgatgtg ctggaattaa
    17761 gttattctcc gatcacgggg ggagaaggaa atatcgagtt cttggctcac ttgaggaaag
    17821 tacccgaaag cggaacaatc aattcagcta ttaatatggc agaagtggtt tcaaatgcac
    17881 acgaacagtt tgaccataaa taaattgtaa ctgtgaaaat caagtgagaa gtatgcggat
    17941 tcttctttat tataccaagg aaataagcta tcattgatta agaagaatat gctaaggagc
    18001 gaagacgtaa tgagaaaaaa agatcggcat cgtttgatta ctcgattgtt gagtgagcaa
    18061 gatatccgaa agcaggaaga atttgttgaa atcctgaaaa gcaaaggaat atctgttact
    18121 caagctacga tttccagaga tataaaggaa ctgaaactga tcaaggtacc ggcttcagat
    18181 ggcggctacc gttatagcat accagctgaa acaaacgaag atgtaaatac taaattggaa
    18241 aaactattaa aagacgcttt cgtggcagtt gaccaaatgg aaaaatttgt tattttgaaa
    18301 acattgccgg gaaatgcttc ggcagcagca aatttgattg ataaacgtta caagaaagaa
    18361 ttattttcga ttatcaatga tgacgataat gttttgatga ttacacgaac tgaagaccag
    18421 gcagttttat tgaagaaaga cttcctgcat tacctttaag ttgaggagcg aatgtgatgc
    18481 tacaagaaat cagtattact aactttgcga ttattccgga attgcggctt tcttttcacg
    18541 aaggaatgac cgcgctgacc ggagagactg gtgcgggtaa atccattatt atcgatgctt
    18601 taggtctgtt agcaggagga agaggttcaa gcgattatat acgtcaagga gcagaaaaat
    18661 gtgtgcttga agggttgttt gaactaccaa aacaagaagg attctctgaa ctgatggttg
    18721 aattagggat cgaaacagat gaggacaatc tgattgttcg acgggatatg tccttaactg
    18781 gaaaaaatgt ttgtcgagtg aatggtcata ttatcacatt agctaatctg agaagaatcg
    18841 gcagttattt agtagatatc caaggacaaa acgaacatca ggaactgctc cagcctgaat
    18901 cacatcttgc tttattggat cgttttggag atgtagcttt ccaacagaag aaaaagagtt
    18961 atcagcaaga atatatctct tatcgtgagc tggaaaaaag ggtacgaaaa gtgcagcaaa
    19021 atgaaaaatc ctatgttcag agaatagata tgctccattt ccagcaagaa gaaatagctg
    19081 ctgctgattt gcaagtcgga gaagaagaga aattaaaaga agaaagagaa aaacttagca
    19141 attatcaaaa aattgctgat ggattagctg caggttacgg agcactgacg aataatgaac
    19201 aaaacagtgt agatggtgtt ggcttggccg tttcagaact gcaagggatc gcccatctag
    19261 atgtggagta tgaagcaatt tatgaaaata tccaaagtgc ttactatttg ctgcaagatg
    19321 caatcggcga tatgagtcgt cagattgatt tattggagtt agatgagagt cgtttagaag
    19381 aagttacgca acgtttagaa ttaatccgac agttgaaacg taaatacggc gaatccattg
    19441 agtcaatatt ggcttactat gacgaaatca ccgaagagct agcttcttct gatttttcag
    19501 aaggtcaatt ggacaaaatg aaagaggaac tagagcaaaa agagcttcta cttcagcaac
    19561 aagccgcaga tcttcatgaa gcgcgtaaaa aaatcgcaaa agaattggaa aaatccattc
    19621 tgcatgaatt gaaaagtctg tatatggaaa acactgagtt tgaggtacgt ttcttaaaag
    19681 aagaaaatag acaattgaat catgatggat ttgaccaaat cgaattttac attacgacca
    19741 atccaggaga gccactgaag cctttggtga aagtcgcttc tggtggcgaa ctgtctcgga
    19801 tgttgcttgc tttgaaaact attttttctt ctgagcaagg tgtgacaagt attatttttg
    19861 atgaagtgga tacaggtgtg agcggaagag ttgcacaggc catcgcagat aaaatttctc
    19921 aaatatcgaa atactctcaa gttttgtgca tcactcatct gcctcaagtt gctgcagtcg
    19981 ccgactatca atattatatt gtgaaagcag tgattgatgg acgtacgcaa acttctgttt
    20041 cagagttgaa aacaaaagaa agagaagaag aaattgcacg tatgctggct ggaagtgaga
    20101 ttacaaaact cacactcgaa catgcaaaag aactattgaa actcgcaaaa aggacctgag
    20161 ccacctcgca gtggttcagg tccttttcag cagctgatag ctatatttt
//
LOCUS       DAXLPC010000049        19457 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.049, whole genome shotgun sequence.
ACCESSION   DAXLPC010000049 DAXLPC010000000
VERSION     DAXLPC010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.049"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(65..265)
                     /locus_tag="ACF3UE_001673"
     CDS             complement(65..265)
                     /locus_tag="ACF3UE_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3635078.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(717..1037)
                     /locus_tag="ACF3UE_001674"
     CDS             complement(717..1037)
                     /locus_tag="ACF3UE_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635079.1"
                     /translation="MKKRVLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(1540..2658)
                     /locus_tag="ACF3UE_001675"
     CDS             complement(1540..2658)
                     /locus_tag="ACF3UE_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635080.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPEIEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            2891..3013
                     /locus_tag="ACF3UE_001676"
     CDS             2891..3013
                     /locus_tag="ACF3UE_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635081.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            3129..4436
                     /locus_tag="ACF3UE_001677"
     CDS             3129..4436
                     /locus_tag="ACF3UE_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFD3635082.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGESRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANMFVIGWRRVAEFFGNLF"
     gene            4555..5754
                     /locus_tag="ACF3UE_001678"
     CDS             4555..5754
                     /locus_tag="ACF3UE_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFD3635083.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(5781..7049)
                     /locus_tag="ACF3UE_001679"
     CDS             complement(5781..7049)
                     /locus_tag="ACF3UE_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFD3635084.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKAEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     regulatory      complement(7104..7170)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(7212..7859)
                     /locus_tag="ACF3UE_001680"
     CDS             complement(7212..7859)
                     /locus_tag="ACF3UE_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HFD3635085.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILDHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(8267..8770)
                     /locus_tag="ACF3UE_001681"
     CDS             complement(8267..8770)
                     /locus_tag="ACF3UE_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFD3635086.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(8893..9657)
                     /locus_tag="ACF3UE_001682"
     CDS             complement(8893..9657)
                     /locus_tag="ACF3UE_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFD3635087.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMALTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFMVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKENAESLNVGVAAGIVLYHFSL"
     gene            9765..10040
                     /locus_tag="ACF3UE_001683"
     CDS             9765..10040
                     /locus_tag="ACF3UE_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFD3635088.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEEDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            10717..11667
                     /gene="yidC"
                     /locus_tag="ACF3UE_001684"
     CDS             10717..11667
                     /gene="yidC"
                     /locus_tag="ACF3UE_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFD3635089.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(11846..12820)
                     /gene="lacD"
                     /locus_tag="ACF3UE_001685"
     CDS             complement(11846..12820)
                     /gene="lacD"
                     /locus_tag="ACF3UE_001685"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFD3635090.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(12817..13275)
                     /locus_tag="ACF3UE_001686"
     CDS             complement(12817..13275)
                     /locus_tag="ACF3UE_001686"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFD3635091.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIAHDEKDVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIVTLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTKIATILTKEIGEDL"
     gene            complement(13272..14738)
                     /locus_tag="ACF3UE_001687"
     CDS             complement(13272..14738)
                     /locus_tag="ACF3UE_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFD3635092.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDASMGMMVPVLAAYIAEGIAKRPGLIVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDDSKAANRTVIEKGRAGDLS"
     gene            complement(14720..15670)
                     /gene="pfkB"
                     /locus_tag="ACF3UE_001688"
     CDS             complement(14720..15670)
                     /gene="pfkB"
                     /locus_tag="ACF3UE_001688"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFD3635093.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIREERFERWENIN"
     gene            15813..16562
                     /locus_tag="ACF3UE_001689"
     CDS             15813..16562
                     /locus_tag="ACF3UE_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3635094.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINVLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISQKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
     gene            16828..18306
                     /locus_tag="ACF3UE_001690"
     CDS             16828..18306
                     /locus_tag="ACF3UE_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HFD3635095.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(18374..>19457)
                     /locus_tag="ACF3UE_001691"
     CDS             complement(18374..>19457)
                     /locus_tag="ACF3UE_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFD3635096.1"
                     /translation="LNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDNMND
                     YYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLAAQA
                     GVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKKIPY
                     STEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYFGFT
                     DKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHIYNI
                     GNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSALERD
                     FEFKPSTSLRDGLRKFAQWYKSFYEV"
BASE COUNT         5999 a         3993 c         3390 g         6075 t
ORIGIN      
        1 agaaaataga caaaaacgcc cagacacgca aatgtctggg cgtttatttt ttagtatagg
       61 ttaattaagc tttagtaacg tttgttgctt gaggtccgcg ttggccttct tcaacatcga
      121 aagttactgc ttggccttct tctaaagttt tgaatccgtc gccttggata gctgagaaat
      181 gaacgaatac atcgtttccg ttttctgcag tgatgaatcc aaatcctttt tctgagttaa
      241 accattttac tgtacctgtt tccataataa aaatcctcct tgtgtatcaa cacatatttt
      301 gcaattactt gaatggtgta tatctggaag atgtttattt gaaacaagct accacagatt
      361 accgaacaaa aactactcct atagtatatc ataccgttta caaaaaagct agagtttttc
      421 gacttttttt attaaaaaaa gttttctcag cgattacata aagtgaaaaa ccgaactttt
      481 tttaaaataa acgaaatatt gttcagttgg tgtttttttg ctctgatgtt cttctttaaa
      541 ctaaaaaaat tattctttct gactacttat cggttctgtt tcaacggtcg aggctgggga
      601 agattcttta gtaggtctga tgttctcatg gtatttctga tagcctatga cagtgaccag
      661 aagaacaagg caaaccaata cgatcaacga gattagtttt tcttttttgc tcatatctat
      721 acctcataaa taacaggatg atgtccatca tatttctgag tatgagtaaa agcaaaagct
      781 gcagctgtag aatgtaagaa atgccagcaa ctttcataat cacaggtcgg acagtaccaa
      841 aagtaaccaa atcttggctg caaagaccgt tcttctgttt caggaatcgc agaatcaaga
      901 tctgttgtct gtacataaac atttttgtac agacgtgtgc ctgtaatagg agaccgctgt
      961 gtttcttcag caaaaactgg ctgacttgtt aaacttaggg atagaaacag caaacaccat
     1021 aacactcttt ttttcataaa gacctcctta tcgataagtt tttcccaatt aaaatcatat
     1081 ctcaagaacg cccgttattc acattttgtt cataaatgat gttttttgta tcataatcgt
     1141 caaaaagagg tcgtgaccac gtcacaacct cttttttaaa tggtgttcca gaagtagctt
     1201 cttcggaaat aagccgaaat ttcacaaaaa tttgagaaat aatttttgtc aatctcttct
     1261 tatttcttga agctgaccac ttctgtcaca acctcttcct taaacggtgt tcaaaagctt
     1321 gcatctgcgg taataagccc accaaacaaa aaatatgaag agctattttt gcttgctgtt
     1381 cttattactt gatgcagaac agctttttca caacctctca tacacggtgt ttaatcagct
     1441 gaccttcggt attagctcaa aaaacggcaa aatatgtgaa actatttttc cgtttgtttc
     1501 tctaatactc aggtcaaaac actgttttca caacctcttt taataacgaa gaatcgctgt
     1561 cagactcttt tcatctggcg catctttttg atccaaaata aacactttcc cgccattaat
     1621 gatcacatca tctgctaatg cattcaacac ttgacgccga tcatattcta tttcaggatc
     1681 ttcaccgaaa ccatcagcta agtttgacgt agcgataaat agatgcgaca cttttccttc
     1741 tttcgcagct ggaacgatat caactaactg atcgatgaat ttcttatcta agagtttatt
     1801 gtattctttt gattcttgag ctgcgagttc acttgacagc ttcttcgccc cttcttcgat
     1861 atctctaaag gatagctgcg caggagaagc agaaatcgca acgtctgcac aataataggg
     1921 atttttagca atttttttga acatcgtctg attttctggt aatgcaaata aataaatcgg
     1981 ccattgttct ggattttcga aagaatcctt caagtacgta tcaacagctt ggtaatagtt
     2041 gacccaatcg atctctactt cttcatcttt tggatttacg ccatggaaag ttactccatc
     2101 tcgggctccg cctcctccat tagaagagaa gttcaaaccg ccacctgtca gttcagatcc
     2161 caatgcagta acgacatcaa ccggtgcccc ttctggtaga gatacttctt ttacttgttt
     2221 gttgctgact tcatacaatt tcatggagtc gcggttcaat cccaacagat aataggaata
     2281 gttgaactgt ccatttttga taatggccag taaataagga agatcactta catagtattg
     2341 atcgtctacc gggatactca aacgatggat ataggtttgg tcagcagtta taatgaccgc
     2401 tacactcgta gttgcactac gccaaaacga aggatctcct aacaaatttt caattttttc
     2461 ttggaacggg gaccagtcat gttcggaata ttttttctca aaacgtttct ttgcttcttt
     2521 cgcaaaattt ttgaatttga tttgatcttt ttccacatct tgatgggcga catgcgtatt
     2581 cagcatgatc gtgacgaatg gtcctttagc gccttctgaa gtcaattgtg acaataattc
     2641 tttatccttt tttgccataa acgtacccct cctaaaaaaa tcattccttt gtttctatct
     2701 aaagtctacc acaacactat ttttccatac aataaaacgt atctaaaaaa ataaaacggt
     2761 ttctacggtt ttaaatttag ctattttttt aagttatctt cataatttcc tcaattattt
     2821 agccccagtc ttcaactatt cttcatgaaa tgctgataaa ctaaaaaaaa gaataaaaga
     2881 ggtggatctt atgcatttga ttatgatttt cagtttatta agtattatca gtttatttgc
     2941 tttcagcgct tcccgcttat tagatgcgga aacacagcct attcctgtaa aagtacgtaa
     3001 aaacgaccgc taaccttcca taacgtgcgt tcttatccta aagttttttc agaaacattg
     3061 aaactctctc ccctctctga taaaatttta atttgtagcg aaacaaatta attacaagga
     3121 gatcggatat gtccataaaa aaaacacgtc tagtcctatt attggctagt ctcattcttt
     3181 gccttgcttc ttttctacca gctgttgctg tgcaagctga agatacgttc aaagtaaatg
     3241 caaaagcagc ttttgctgta gatgcgcaaa gcggtaagat tctttatgat caagatggag
     3301 aaaaaaccat ggggatcgct tcaatcacaa aaatcatcgg tctttacatc gttcttgatc
     3361 aagtaaaaga aggaaaacta tcatgggatg ataaagtttc gatttcagat tatgcagaaa
     3421 atttgagtat caccccagat ttatcgaatg ttcctttgca taaagaaaac acctacactg
     3481 tcaaagaatt attcgactct gcaatcatcc agtcagccaa tgcttcaatg gtggccttgg
     3541 cagaaaaaat ctctggcagc gaagctaaat tcactgaacg aatgaaagaa caattgaaag
     3601 attggggaat caaagatgca acgatcgtta atgcatcagg actgaataac tcttatcttg
     3661 gcgaaagccg accagaaggt actggagaaa acgacgaaaa tcaaatgtct gctcaagatg
     3721 tggccatcgt ggcccgtcat ttgatcttgg attttccaga aatactggac gtatctagca
     3781 ctacgacaca aatgtttggc gaaaacacgc aatcaccagt ggaaatggtc aactggaact
     3841 ggatgctccc aggattcgtt aattacaagg aaggcgtgga cggattaaaa actggtacga
     3901 ctgagcttgc aggtgcttgt ttcgttggta cgatcactaa aaacgatcaa cggatcatca
     3961 ctgtcgtatt gaatgcggac ggccatgcgg aaaacccgag tgcccgcttc aatgaaacag
     4021 accgtttgat ggactactgc tatgacaatt ggtcagaaaa agagctcgga aaagctaacg
     4081 caagtattcc tagcctaaaa accattgatg taaaagacgg aaaagaatca acagttcctg
     4141 ttgtgcttaa aagccctgta aaagtatggg tacgaaacga tatggatact ggcaaattaa
     4201 cgatcacgcc aacacttgac aagaagcaag tcactgacaa cgagatccaa gcacctatgg
     4261 ataaaggtac aaaaatcggt accgctacga tcaccttggc agacgataaa ttaggctatt
     4321 tagaagacaa caatgcgcca tcaacagaga tcattacgga taaaacagtg gaaaaagcga
     4381 atatgttcgt gattggctgg cgacgcgtcg cagaattttt cggcaacttg ttttaattga
     4441 acaataagaa aagcatcttt ccatcggaaa gatgtttttt tgctttttct agtttaaata
     4501 acagcttttt tcatctattt tcgttatact gtataagaaa aaggagttga atttatgaat
     4561 ctaaccagag atctgatctt tttagttctc tatcttattg gggtattctc tatcgtttat
     4621 tggcgaaaac agaagaagga tccttccttg ttcttttacg gcagtacgtg gacatttacg
     4681 gtaatcttaa cttattttgt cgtgttggaa attttttatt cgacctttta ttttttgatt
     4741 ccattgttgt tctttagtat ctttgctttt tcttatttca cagaaaaacg aaggctgctg
     4801 aatggtcttt tattcaatgt tttcctcatc agtttcggca tctacttgtt tgtcttgctg
     4861 tatgaaacgc aaaatatttt ccttggcgga ctgatcgcct tgatcacgat tccattgcta
     4921 cttgtccttt tatttggtat ttatggattg attgtttttc ttttttggaa cggggtcaca
     4981 gttttacgta gagaatcgca ttcattagcg aatcttttaa cgttgatact agccattttt
     5041 cttacactgt ttcttgtttt tgactttttc ttgttaaaat atttgccgca atggataaat
     5101 gctttgtttt tctgcgttcc cctgatcttg atctatctat ttatcgtatt ctacaacttt
     5161 ttgactgtct cattcttgta ccagttcaac cggcctcgat acaatcaaga cttcatcgtt
     5221 gtgttaggcg ctgggttgat caatggagaa acagtttctc ctcttctagc caagcgaatc
     5281 aataaggcaa ttgcttttta tcgggctcaa agccgtgcta cattaaatcc gcccatctta
     5341 ttgatgtctg gcgggcaagg agcagacgaa aaagtaccag aggccattgc gatgaaacaa
     5401 tatgccatgg aacaaggaat ccctgaaaga gacattcttg tcgaaaccaa ttcgacaacc
     5461 actttggaga acatgctcta ttcaaaggaa atcatggatc agcaaatgaa agggccatac
     5521 cgcgcgatct ttagttccaa caattaccac atttttagag ccggtcttta tgcgcggcaa
     5581 gccaaattga aagcaaatgg tattggtgca aaaacagctt tctactactt gcctaatgcg
     5641 tttttaagag aatacatcgc catcttgatg atgaacaaaa aaagacatat gatcatttgc
     5701 ggattgcttt tcgcaggctc cgcattctta tcgctgatta ctttactttt ctaaaaaaac
     5761 aaggtgtgac aaaacatatg tcacaccttg tttttttctt tcattctctt aactattggc
     5821 aaaaagagta tccctttttt gaccgctact tgctgagcag aataaatacc gctgttgcct
     5881 gaacacataa agctgatcaa gcagatcata aagaagtaaa cagccgcttg tgaaccgaac
     5941 aattcgatcc ccatcacaaa gcaggcaatc ggtgtatttg tcgcaccaga aaatactccg
     6001 ataaagccca atcctgcgag aaaaggaaca gaaacatgga gcaaaggcgc tagtgctgca
     6061 ccaagcgttg caccaatttc aaacaatggt gtcacttctc ccccttgata tcccgcgcct
     6121 aaagacaaaa ctgtgaagaa taacttccca ataaaatcat agacatgtgc ctgtccatta
     6181 aatgattctt gaagtaacgg aagactcaat ccgagataac gttgtgtttg caaaatcaat
     6241 gctgctgcca caactacagc cccacctatc gtatttcgcc aaacaggatg aggaatccat
     6301 tgtgcatacc gtgcttttaa aaagacgatc gaacggctga atacccagcc aatcaaacca
     6361 aaagcaatcc cagcaacaaa aactttgaag aacagcaaca tactccattc agggatcaca
     6421 cccatttggt aatgtaggtg agaaacacca tagctttccg tcatgaaatt tgcaaacagt
     6481 gcagcaaaga agctagggaa gatcgcttct gttcggactt tcccgattgc caacacttct
     6541 aatccaaata atgttccagc taaaggtgtg ccaaatacag aactaaaacc cgcactgatt
     6601 ccactgataa tcaagatttc ccgttctgct ttatccaatc ggaacaaacg tgctgtatta
     6661 tctgctaacg ctccccccat ttggactgct gttccttcac ggccaacaga tcccccaaat
     6721 aaatgggtag ttatggttcc aaacagtgta agtggaataa gccgcaacgg gattttttct
     6781 tctccaccat ttccttgatc gatcactaag ttgtttccac gactagaaag tccgccgtga
     6841 tacgcataga gataagcaaa aagcgcacca ctaactggta gtagataaag gagccaagga
     6901 tgtgatagtc ggatatctgt cacaactgtc aagctattta agaaaaaagc agacaagctc
     6961 cccatgaata taccgagaat cgctgtgatc accagccact tcagcatgta cactaaaatg
     7021 cgtactggac tcggtaattg tttttccata aaaaattcct cctcaataaa aaaacgccta
     7081 ctaaagaaag gggctatccc cagactttag taggcgtcat tagctatctt tcgttagcat
     7141 ttaaaggcga acaccatcac ctattcactt ccattaaaag atagcatatt tttctgtaaa
     7201 aaacaataaa attatcgttc tttctttaca cgttcagcaa attcatagaa aggagccaat
     7261 ttcgttaact gttgattaca ttggtcacta tcatgacaaa tataattccc ctttttcgta
     7321 tacgtgccat cagaacctgc tttcgttgta gaaagaaaaa gcgaaacatt cgatgttttc
     7381 tgacagattg cacagattcc cttatttatc gttggtgata aagtaccgct aatccctttt
     7441 aatttttcat cttcgtaata gaccatgaat tttttctgcg tacctggatc attccagccg
     7501 atgtacgtat gttcttgcaa gtcgatttca ttccaagctg gttgtttgag ttttttcact
     7561 tttcggaata atttctcgat ttgtggtttg ctaggctgca taaacggctg aacgatttgc
     7621 ttcagctcct ccaatgctct ttctgcttgc gcttttgtca gttttacgtc taaaactgtc
     7681 gttaaaaatg tatcgatttc tggcagttcg tgatctaata tgtctcgaat cttttcagct
     7741 gctagtgcct gaactgtttg caccgttttt ggatcattga cagatgagta cgcatttaat
     7801 aactgttcta cttctctttt tataaaaaaa tattggtatg gttttattgt ttgttccatg
     7861 attttaaagt cctttcttct aaccaaagtg catactttgt agaaaaaagt gatcttctgc
     7921 aaagtatgtg ttacctgaag atcccggact cttttaaata agatacgttt tgcatcttat
     7981 catcaccccc tttaatgctt attcttctat gtacatgatt cattcgataa ataaaagtaa
     8041 accgtatctt gaacagatag tcaactgcaa acagaaaaaa ggactgtgac aaaagtcgtg
     8101 tcaaagtccc ttgtttcgaa tgaatggtgt tcaaaagctt gcatctgcgg taataagccg
     8161 aaacttcaca aaaatttgag aagtaatttt cgtaaattcc ttcttatttc ttgaagctga
     8221 ccacttctgt cacaacctca atatggtcta ttattggttt tacctgttaa atcgaggatt
     8281 ctttcccaaa gtaacgttgc catctcttac gcatacttgc agacatgggc tgtgccgctt
     8341 ctttgactgc gcagtatttg tccacgaatg tcacgatata tccttcttta tacttaggcg
     8401 gtgcgatcgt tgcaccccac atgtgcttca aaatgatatc tcgctcaaga tccgacaaat
     8461 cggtgatttt ttctgcattc tttacagcaa ttcttggatg gatatacgca tgtgtcccct
     8521 cgtcaaattt cgtcgtacgc caatcatagt agaacagatc atgcaaaagt ccagcacgcg
     8581 ctgttgcttt agcattgcca ccccattttt ttgcgagcag ataactatag taagaaacac
     8641 tgatggaatg ctccaaacga gtggaatgaa catgctgtgt gtaattcgct aattttttca
     8701 ctgcttctgt ttctaaaaga tcttgtacat aagacatata ttcttcgtct tcacgccatt
     8761 tttctgtcat aattatcgat ctgccacctt tttgaatttc attttcttct gaaattgatc
     8821 taagtatacc accagtgttc ggattattct agtcgctcta gataaaatag ctaaagctta
     8881 atagttcctt aatcataaag aaaaatgata aagaacgatc cctgctgcga ctccgacatt
     8941 caatgattcc gcattttctt tcattgggat atatacgttc tgatcagtca aagacaagat
     9001 ttcctgactt actccctgac cttcgtttcc catgattata gcgaaatcct ctgttttttc
     9061 tactttgtct aatgcatgtg cttcttcatt taattctgta ccgtacacca taaacccttt
     9121 gcctttcatt acagggatca cttctgccaa atctttttgt aacacaggca aatgataatt
     9181 gcttccctgc atgcttcgca gcacctttgt actataaata tctgccgttc ctttacctaa
     9241 taaaacacca gccataccaa acgcatctgc cgtacggatc atcgttccca catttccagg
     9301 atcctgtaca ttatctagta aaagccagcc tcctgaaaaa tctggcgtat cttcagatgt
     9361 taacgccatc actgctaaga tcccttgcgg tgtaggtaga tctgacatag cggtcatgac
     9421 ctcatctgaa actagaaaag tagaaatctc tttgtttaca gccagccagt ctccccattc
     9481 tttcatacct ctctgtgtca caaaaagttc ttttatttct gcatcagacg acgcagcttc
     9541 ttcgatcaga tggaaccctt ccaaaagata ttctgccttt tcttctctgt atttcttttt
     9601 atgtagtttt tttaattctt tgattcttgg attttttgct gattggatct ctttcacatt
     9661 ccttcacctc acctgattat atcatggaat aggtgcttga gcttgtttca tcctaaaaaa
     9721 atcggtatca ttgatttata aaacaggaaa gaaaggtgac gaacatgcgc aaagttaaaa
     9781 tgaatgtcca aggacgtgtc cagggcgtgg gatttcgcta tatgaccaag atggttgctg
     9841 atcagttagg cgtgaccgga acggtaaaaa acgaagagga cggctcagtc acaatcgaag
     9901 caatcggaaa tgacgacatc atccaaaaat ttatcgaaga agtcaagaag tctccgagcc
     9961 caagtggacg agtgcagtat gtggatgtcc aagaagatcc gatgattgag gaacgaaaga
    10021 aatttgatgt ggtgggataa ggttgtgaaa aggtcgctta gttttgagta ttaaggaaaa
    10081 ttttgtgaaa atgtctttcc acatttttgc ataaatttga cttaataccg agaaactgac
    10141 ttttgaacac cgtcgataag gttgtttttg aagcgctttg cctcgagtat taaggagaaa
    10201 cattttcaaa atagcttctc atattttgaa atgtaatgac ttaataccga gaggcagctg
    10261 ataaaacacc gtcaataagg ttgtgaaaaa gctggtctgc atcaagcatt aaggactggt
    10321 tgtgaaaaat agctctccat atttttcaac aggctggact taatgccgta gatgcaagct
    10381 tttgaacacc atcgataagg ttgtttttga ggcactttgc ctcaagtatt aaagacaggt
    10441 agtaaaaaag ctgatctata acttgcaatg aatttgctta acccatattt tccagacaga
    10501 acaaaaaagt ttttagtttt ttaaataaga aagaaacact tggaatcact cttttctttc
    10561 taagtatttc tttcttgatt ttttgtcttt tttcaaaatt tttcgctacg aaaaagaaag
    10621 aatatttata tgaaatttct atgaagttga ttgaattcca tgcgcttttt tagtatagtt
    10681 aagtttgtgt aaaaattata gaagaggaag tattctatga ataaatggaa aaactggtta
    10741 ttgggatccg gacttgtcag tatcctgctc tttttatctg gctgcgtgcg gatggattca
    10801 aacggaaacc ctgacacttc aggaatcgtt tatcgagtac tcgtccatcc tatgggccaa
    10861 gcgattacat atctagttga gaatttcaat tggtcttacg gctgggcagt tattgcaatg
    10921 actgtgatcg ttcgtatcat catcttgcca ctaggtatca gtcaatcgaa aaaaacaatg
    10981 atccaatctg aaaaaatgca agcgttaaaa ccacaagttg aagcagcaca gcaaaagcta
    11041 aaagctgcaa caacacgtga agaacaaatg gcagcacaag cagaaatgca gcaagtatat
    11101 cgcgaaaacg gattgagtat gaccggcgga atcggctgtc tgcctctatt gatccaaatg
    11161 ccgatcttct ctgccttgta ttttacggct cgctacacag aaggtatccg tgaatcatct
    11221 ttttacggca tcgatctagg ctcaccaagt atggtgcttg ttgccattgc aggggtcgct
    11281 tatctgcttc aaggatatat ttcaacaatc ggtattcctg aagaacagaa aaagacgatg
    11341 cgtacgatgc tgatcgtctc tcctgctatg atcgtcttca tgtcgatcag tgcgccagcc
    11401 ggtgttacac tttactgggt agtcggtggt gtgttcagct gtctgcaaac attcatcaca
    11461 aacgttatga tgaaaccacg tttgaaagca caagtggcag aagagttgaa acaaaacccg
    11521 ccaaaacaag tcgtcactcc aagaaaagac gtgacagaat cagcaaagcc agctaacaac
    11581 aaacaagcaa caaaacaaat caaacaacca aaaaacagta caaacaacaa aggccgcaac
    11641 gcaggaaagc agcagaagcg gaagtagata gtaaataaga gtgtaataaa aattcattaa
    11701 cagttttagc aattaaaaat atcgaccaag atttttgaaa aagaaatctg gtcgatattt
    11761 ttatttaagt gaatgtttaa tttgaatcat cgattgatcg ctatctaatt gcagcagcat
    11821 ctttttatga agaaacaact ttttcttatc tatcaacgta gacaggtgtt gctgtttctt
    11881 ctaatagtgt acttaattcc ttaatatttt gttttccttc ttctaacatc caactactcg
    11941 ctttttcttc gccttcggta acaaaaggcg ccactccctt cgcccatgtt gctcgcccac
    12001 ataagacacc attgaatgtc gaacctgatt gttttgcaaa acgtaatgta tcttgaaata
    12061 gcgtagcatt gactcccgca cttaaaaaaa taaacggttg ttcagtcact ttcgattgtt
    12121 catagaaata cgcggatgcc tctgcttgac tataacaagt ctcttgccca tatccttcca
    12181 caaatctcat attcactggc acttctactt tcaatacatc cacttgataa cgttcttttg
    12241 aaaattctcg catggcttca ataactttat gtggttttac ttttgcatag gcaagagaag
    12301 acggatcgcc aatagttgca tcataagaga ggatctctaa aaagaaaggt atgccttctg
    12361 cttcgcattc tgaaccaatc cgttctataa ctatttgttt ttgcacatta atctctgctg
    12421 gttcatcaac gtcatagtac aataaaaatt tacaagcatc cgcaccagct tcttttaacc
    12481 ttttcaccga ccaaatattc aataaatcag gtaatcttcc cggaattttc gtatcatagc
    12541 cggttttttc ataagctagc agcaagccac attctttctc tcgaagcgct gctgcaggca
    12601 ggccgtattc tggatcaagt aaaatagctg aggcataggg agtcaggtat tgagaaacca
    12661 tctgtttaaa ttggatgatg tcttctgatg tagcttcttt atattggttg atcattttct
    12721 tcaaagcacc acgctggtcg attgctaacg cgctaataat tccagcttca tccgtcaatc
    12781 gcttcaaacg ttcctgcttt tctatactca tcttcttcat agatcttcac ctatttcttt
    12841 agttaatatt gtggctattt ttgtttttga ttttgctttt ctcaactgtt ctgtaacctc
    12901 ttttcgcatc aatgatcgtg caacgagaga caataatttc aaatgagtcg ttcctgcttc
    12961 tgaatctgga ataaataacg caaaaataaa atcaactgac tgtctatcta aactgttcca
    13021 ttcaattcct ttgttcagtg tgacgataat catactaggt tcgttgattg tttgagactt
    13081 cgcatgagga atagcaaaac ctgacattat tcctgtagta ccttcttttt ctctttctag
    13141 aagtttttga tatacatctt tttcgtcatg agcaattcct aagcagaatg tttgctttgc
    13201 taaaaactta aatgcttctt cttgactatc caatggctgt tgtaaaaaaa tgttctcttc
    13261 atgaatgatt gtcatgataa gtctcctgct cttccttttt cgataactgt acgatttgct
    13321 gctttactat catccatctt cttgtcttta tcagttactc ttttcttttg gattaatcct
    13381 agtatcactc caccaacgat cgaaccaata agaatcgctg taacccattg gatttttcct
    13441 gttactacag gtaatactaa aaaaccgcca tgtggtgctg gaacttggac gccaaacaaa
    13501 taagtcaaga cagcagcaat tgatgagcct aacatcatcg tgggtaacac tcggatcggg
    13561 tctttcgcag caaacggaat agctccttcc gtaatatgag ttgatcctaa aataaaatta
    13621 accaaacctg cattacgatc attggtatca aaatatttac caaacaataa agtagcaaaa
    13681 ccagtaatca acggtggcgc aatacaagct gctgacacac cagccataaa agtcgtgttt
    13741 ccttgtgcca aaagagctgt tcctgttaca tatgccgcct tattaaccgg tcctcccata
    13801 tcaaacgcac acatgcagcc aacaatcacg ccaagaacaa gtggattcga atgttcaaat
    13861 ccagctaaaa agctcatcat tccttcattt atagccttca ttggacctgc cagcaaagac
    13921 atcacgatgc caataaatgc tacgccaata actggatata agaagattgc cttcaagcca
    13981 tctagttgtt taggtaaaat tgtcagtagc ttttgcaaaa ataagataaa ataacctgct
    14041 aagaacccag ctaaaatacc tcctaaaaat ccagtaccgc cattcatggc tacgattcca
    14101 ccaacaaatc caacgattaa ccctggacgt ttcgcgatcc cttctgcaat ataagctgct
    14161 aaaactggaa ccatcattcc cattgatgca tcgccaactg cttttaccat tgccgctgta
    14221 gcattgtatt gtgcatgatc tggatcaaaa gaatagattc cccaaacggc aaatgaaata
    14281 gcaatcaata ctccgccagc taccacgaaa ggcaacatat gagagacacc gttcatcaaa
    14341 tttttataga tgctacgacc aaaattagca ccactcatcg cttctggttc taaagtatca
    14401 gcagcttcat tatctgctaa gacagtacct tttcctgcca atgcttcgtc aatcagccgt
    14461 tgtgcatcct tgattcctgt actgacagaa acatcaatga ctcgttttcc cgcaaatctt
    14521 tctgaatgga catctttgtc tgcggcaata atgacagcat ctgcctgttt gatttcttca
    14581 gccgttaatt cattttcgat cccaatttgt ccatgggtct ctactttgat cgtgatgcct
    14641 tttttcctag ctgcttgttc taatgcctct tgcgccatgt aggtatgcgc aattcctgtc
    14701 ggacaaccgg ttgctgcaat tagttgatat tttcccatct ttcgaacctc tcttccctga
    14761 ttttgatttg tttacttaat tcctccacat ctaaaaaatc tgttaatcct ttgcgaaaag
    14821 cggttgagct gcctgctgct atgcttttac gtaacgtttc atcaagcggt cgtcgattca
    14881 tgtatcctgc taaaaaagcg cctaacatgg tatcacctgc acatgctgta ttgacaactt
    14941 ttccttttgg cgagtttcct cgaaacaccc tgtctttcgt aaaaagaatt gctcctttct
    15001 caccgaggga taacaaaaca ttttctgcac ctaactctac tagtcgttgt ccataaacaa
    15061 agtaatcttc atctgtaacc atttttcgtc cgaaccaaga agaaagttct tcctcgttcg
    15121 gtttcagcaa aaatggtcga tagggtaaac aatccatggc ttcttgatca ctactatcaa
    15181 taatcaaatg aatccccttt tcctgacaaa tccgactgat ttctattaaa acctttggag
    15241 acagccctct tggtaaactc ccagaaacac aaagataatc ttctgcttgt aatgctctta
    15301 tttgatttaa aaaattatgg acagctgtct gcggtatttc aggtccttga ttcactaatt
    15361 tgtattcttc tcccgtttga ttgacttgtg taaatacatt gatacgcgtc ataccaggca
    15421 cttcaataaa ctctgtttgg atttgtttct gctgtaaata gtcttctata tactttcctg
    15481 tgaacccagc agaaaaacct aatgccgtac ttgggaaatc tagcatcttt aatactagtg
    15541 acacattcac tccttttccg tttgcctgaa tgtcatcctc ttttgtgcgg tttaccataa
    15601 aaggatgcat ctcctctgtt tcaataaata gatcaattgc caaattcatc gtgcatgtgt
    15661 agatagacat aaccaatgac ctccttgact ctattatgaa atacgcgaaa gagaaaatgt
    15721 tttcttaatc gttccaacac aaagaaaacc tttacattta taaactcgtc gtgctatttt
    15781 ttaactaact tttggtgaaa gaaggaaaga atatggatca caaattaagt gaaacagaac
    15841 agtacctctg gaactttatc gaacaccata tcctagagat ccctaactac tccatcgtga
    15901 aactaagtga acaagcaaat gtctcaacag ccaccattgt gcggacaatg aaaaagaaag
    15961 gctatgaagg gtttacttcg tttaagcatc atctaaaaga aggagaaaac aagaacatca
    16021 atttttcttt cttagataaa gtagacaaag gtatccgccg agccattcta aaaaatgaac
    16081 aagaagtggt acgtacgatc aatgtgttgg aaatcggaaa tattgaggat gcgatacaaa
    16141 gaatcaaatt tgctgaccgg gtttttgtct ttgcccgagg attttcagaa atgattggcc
    16201 aagaaatgct ggtaaaactt caattaacgg gaaaaaattg tcaaatgcat actgatccag
    16261 aaattatcaa aagcatcagt cagaaactga ctaagaaaga cagcgttatt tttgtttctt
    16321 tgaacggcga gacaaaagaa ctcgtcaccg ccgcaaagaa ttgctatgat gcagagattg
    16381 gttcgattct agttacagcc aatcattcct ctacactgaa agactattgc gagatcaatc
    16441 tcgtaggttt caaatcagaa ggttcttatt tccctgatta tgaagtacgg tcacgcttgc
    16501 ctctccagat tatcgcgaga attctgcttg acgcctatgt attgcgtatg ggggagaatt
    16561 gagaagcagt ttattatggt tggttacagt ttaaaacatc acatttttta ttctttatat
    16621 tgtatagact cacgtaaact ttttatgtat aaagttattc acaatctata aagttacttt
    16681 aagtaacaaa aaataattga aaatacttaa aatcaaaaaa tatcttttta atcaataaaa
    16741 aaattgacag ttttattaat aataagctat tctgttatag aagaaaaaat tgtttgttat
    16801 tattagcaac aaaaaaagga gtgcatcatg aaaaagttat ctcaaaaacg tttagctcaa
    16861 atcattattg attctagaaa atctctgaaa atgacacaac aacaacttgc agtagctact
    16921 ggtatcaacc gtgccttaat tagtcgatta gaatctctcg attttatccc gtcaatacaa
    16981 caattagaat cattagcaga agttctaaat tttgaaccaa cagatctatt tataaatgaa
    17041 tcaaataaat caaacagaac aaaacatcag tcgaagaata ttgctgtagc cggtactggt
    17101 tacgtaggtc tttccattgc tactcttctt gcccagcaca atcaggtaac agcagtagac
    17161 attcttcctg aaaaagtaaa acaaattaac aataagaaat ctccaataca agacgattac
    17221 attgaaaaat atctagctga aaaaaatctt aatttaattg caacgactga tggtgcagcc
    17281 gcctatagag aagccgattt tgttgtcatt gctgctccaa caaattatga tagtaaacaa
    17341 aattattttg atacttctgc tgtagagtca gtaatcaaat tggtgttaga agtcaatcca
    17401 aaggcaataa tggtcatcaa gtcgacggta cccgtaggct ataccgaaag tattcgtaaa
    17461 aaatacaata ctaaaaatat tctattcagc ccagaatttc tcagagaatc taaggcatta
    17521 tatgacaatc tatatccttc gcgaattatt gtcggcacgg accaaactga caaaacttta
    17581 cgagaagcct ctcacacttt tgcagattta ctccaagaag gagcaatcaa aaaagatatc
    17641 gaaactcttt tcatgggatt cacagaagct gaagcagtta aattattcgc taatacttac
    17701 cttgcacttc gagtatctta cttcaatgag ctggatactt atgcagaaat gaaaggacta
    17761 aatacacaag aaatcattca cggggtttgc ttagatccaa gaattggcac acattataat
    17821 aatccatctt ttggatatgg aggctattgt ttaccgaaag atacaaaaca acttctcact
    17881 aactataacg atgttcctca gaatatgata agtgcaattg tcgatagtaa tcgtacaaga
    17941 aaagacttta tagcagatcg agtgttagaa cttgctggca cgtatgaggc taacagttcg
    18001 tggaatgcag aaaaagaaaa agaggtagtc ataggtgtat accgtcttac aatgaagagt
    18061 aattcagaca acttccgtca gtcatctatt caaggagtta tgaagcgaat taaagcaaag
    18121 ggggcaacta ttgtaattta tgaaccaaca cttgaaaata acactacatt ttttggttca
    18181 aaagtaataa ataatttaga tgattttaaa aatatcagtc acagtattat tgctaatcgt
    18241 tacgatagta atcttgatga tgtaaaagaa aaagtatata ccagagattt atttcaacga
    18301 gattaaaaaa taacacctca gatttgtagt gtctgaggtg tttctataaa cttttataag
    18361 taaaaaaata caattatact tcataaaaag acttatacca ctgcgcaaat ttacgaagcc
    18421 cgtcacgcaa acttgtactt ggtttaaatt caaaatctcg ttctaacgca ctagtatctg
    18481 cataagtaac tggcacatct cctggttgca ttggaactag ttcggtatga gattcaaagt
    18541 cgtaatcttc tggtagcacc cctgctgcaa ttagctcttg ttgtagaata tctacaaaat
    18601 ctagtaggtt ttccggcgta ttgttaccaa tattataaat atgatatggt gggattggta
    18661 gcccatcttc cccatcaatt ttctctggag cgcactgcat aaccctcttt actccttcaa
    18721 caatatcatc tatataggta aagtcacgct tgcaattccc ataattgaat atttggatat
    18781 tatcaccagc acgaagttta tcagtaaaac caaaataagc catatctgga cgcccagcag
    18841 gaccatatac tgtaaagaaa cgtaaccctg tagacggaat attgtaaagt ttagaatatg
    18901 catgtgccat tgattcatta cttttcttag ttgctgcata caacgatact tgattgtcta
    18961 ctttatcctc tgtagaataa ggaattttct tattagtacc ataaacggaa gacgatgagg
    19021 catacactaa atgttccaca ccagattctc cattatcata tgaatgacga caagcttcaa
    19081 gaatattata gaatcctatt atgttagatt cgatatacat atctggatta gtaattgaat
    19141 aacggactcc tgcctgagct gctaaattca ccacgatact tggtttataa ttatcaaaga
    19201 tgaaatcaat tgttgcttta tcagcaatag aacctttgat aaaattccaa gtagatcctg
    19261 gatggttctt tgcctccgtt tctatctctg ataatctata gttcttaata gagacatcat
    19321 agtaatcatt catattgtca atgccaatga tttttattga tgactgagta cgtaataact
    19381 caagaaccaa atttgatcca ataaaaccgg ctgcgccagt tattaatatt gttctatttg
    19441 ataaggacgt gtttaat
//
LOCUS       DAXLPC010000050        19156 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.050, whole genome shotgun sequence.
ACCESSION   DAXLPC010000050 DAXLPC010000000
VERSION     DAXLPC010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.050"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            88..2877
                     /locus_tag="ACF3UE_001692"
     CDS             88..2877
                     /locus_tag="ACF3UE_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFD3635097.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            2924..3451
                     /locus_tag="ACF3UE_001693"
     CDS             2924..3451
                     /locus_tag="ACF3UE_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFD3635098.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            3472..4662
                     /locus_tag="ACF3UE_001694"
     CDS             3472..4662
                     /locus_tag="ACF3UE_001694"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFD3635099.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            4702..6000
                     /gene="asnS"
                     /locus_tag="ACF3UE_001695"
     CDS             4702..6000
                     /gene="asnS"
                     /locus_tag="ACF3UE_001695"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFD3635100.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVPEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            6930..7604
                     /locus_tag="ACF3UE_001696"
     CDS             6930..7604
                     /locus_tag="ACF3UE_001696"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFD3635101.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLIAQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            7601..7942
                     /locus_tag="ACF3UE_001697"
     CDS             7601..7942
                     /locus_tag="ACF3UE_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635102.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSFFAQF"
     gene            7972..8331
                     /locus_tag="ACF3UE_001698"
     CDS             7972..8331
                     /locus_tag="ACF3UE_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFD3635103.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGISLIVNIIWLIISGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            8592..8714
                     /locus_tag="ACF3UE_001699"
     CDS             8592..8714
                     /locus_tag="ACF3UE_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635104.1"
                     /translation="MNLDKLPATGFKLSCYPVKIKKASAGWIRAVAMIEKKKKE"
     gene            8856..10937
                     /locus_tag="ACF3UE_001700"
     CDS             8856..10937
                     /locus_tag="ACF3UE_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD3635105.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            11248..12714
                     /locus_tag="ACF3UE_001701"
     CDS             11248..12714
                     /locus_tag="ACF3UE_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFD3635106.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            13329..13868
                     /locus_tag="ACF3UE_001702"
     CDS             13329..13868
                     /locus_tag="ACF3UE_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HFD3635107.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            13942..14382
                     /locus_tag="ACF3UE_001703"
     CDS             13942..14382
                     /locus_tag="ACF3UE_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFD3635108.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            14395..14604
                     /gene="copZ"
                     /locus_tag="ACF3UE_001704"
     CDS             14395..14604
                     /gene="copZ"
                     /locus_tag="ACF3UE_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFD3635109.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            14604..16790
                     /locus_tag="ACF3UE_001705"
     CDS             14604..16790
                     /locus_tag="ACF3UE_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD3635110.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            16810..18981
                     /gene="copB"
                     /locus_tag="ACF3UE_001706"
     CDS             16810..18981
                     /gene="copB"
                     /locus_tag="ACF3UE_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFD3635111.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         6399 a         3343 c         4181 g         5233 t
ORIGIN      
        1 tttctttaaa aagcgatgag agtatttttc tgcactttgt agtataattt caaaagaaca
       61 ttagaggcag gagaagagga agatattttg aaaccaagaa cttatgcagt cgttgatatc
      121 gaaacgactg ggacgaatcc aaaagaagat cggatcatcc aatttggctg cgtcatgatt
      181 gaatcaggtc ggatcacttc acgtttttcg atcgatattc atccagggcg gaagatttca
      241 aaacaaatcc agcatttaac agggatcacg aatcaacgcg tccaaaaagc gccttatttc
      301 gaagatgtcg cccaaacgat ttacaatctt ttggcagaca ccatatttgt cgcgcataat
      361 atttattttg attataattt tttgaaccat gaactcatgc gatgcggact tcctagtttg
      421 aagataccag gcatcgatac agtagaactt gcacaaattt tcttgccgac ggaaccaagc
      481 tttcgcttag ctgatttgtc agaaagcctt ggatttattc atgagaatcc tcatcaggca
      541 gatagtgatg ccgaagtgac aggtcaactt cttttgctga tcgaagaacg gatgagaaaa
      601 ttgccaatca tcacgttaga gcagattgcg cgattaagta gacacacagg tatggatacg
      661 agtcgtttca tttatcatgt gattgaagaa atgaaagaaa aaccagagcc acttgatccc
      721 tcattagaaa tcgtcgatgg gctagctttg cagaaaaaag aagtggaact attcacatcc
      781 gtccattatg gtgagcggac atatccaaga aaaaaacaag caaaagaaaa aatgtttggt
      841 aaaacactga tgtatcgaaa agaacagaac agactgatga atgcggtcta cgaccatttc
      901 acaaaagatg aatcaaaaga tttgatgatc gaagcagcta caggaatggg taaaacaatc
      961 ggttatctgc tgccattgag ttatttggct acacctgaaa aacccgctgt catcagtacc
     1021 gtttcgctag ttttgcagca gcagatcata gaaaaagaca ttccattgct gaatcaattg
     1081 ctagatcagc ccatacaacc tgtaattatc aaaagctatc gccactatat tgatttacag
     1141 cgttttaaag gcacacttgt ggaaccgcca gaacaaaaac aatatgcttt gtatcaaatg
     1201 gcggtcttag tttggctgac gcaaacgaag accggtgatt tggatgaatt acatttaaca
     1261 aatttgaacc attcattctt tgcagatatc gcgcacagag gtattggatt tttagcaaga
     1321 aatcagtcat tttacgaaca agactttgtt cgtttcttgc aaaagaaaat caggcaaagt
     1381 aattttttga ttgtcaatca tgcgttttta atacaagaaa cacagcgaaa agaaccattg
     1441 cttccagcta gtccattttt gttgatcgat gaagtacatc atttgccgga aatcgctgaa
     1501 aaagtaaatg acaaacgatt aagtattaac tatttccata aacaaatcca gcaattagaa
     1561 gaaccaaatc agctgtttga ccgaatacaa agctatttac cgaaagaaca tgaagcctta
     1621 cgctggttat cgatttatcg agaagaactt tctgcgctat gcgaagcaca gatttgtatg
     1681 gcagaaggat taatgagttt agtgagcggc aagcaaccta acggacagta tccagaagaa
     1741 gtcatgatga caaaagagat gttggatcag ctgccactgg aatctgggac agccattgat
     1801 cacctgcagc ttttttatca ggagatccag cagctacagt cacaaatgcg tctgactttt
     1861 gagattatcc aagaaagctg gacaaaccag atgcggatcg atttagcaag tttatatagc
     1921 ttatttgatc aattagacaa gcagtacttg ctgatggatc aatggctgga agactggcga
     1981 gatcatttga tccattggtt cgttcctggg aacacagcgc agcagatgat ttttcatctc
     2041 catgattttc aagcggctat gttgccgtcg actgtttggt atcctcgata tgatcgtatt
     2101 ctttatattg gaggaacgct gaagatcggc cctaatcgac actatctctc taagcggctt
     2161 ggcattgaag cagcacctct taaagtgatt gcctctcctt atgattatga gaaacaggca
     2221 aggatctatg tgccaaaaga ggcacctgcc gtccatcaag tcagcaatca agcatatatc
     2281 gattatttag agacagcact tacaggtctg atcgaacaag aagatcggcc aatacttgtg
     2341 ttattcactt ctcatgatgt tttgcagaag gtctatcaga aaatgcatct gtctatgcta
     2401 gaaaaaggac gagaaatact agctcaaggg tttggcggaa gccgggagaa gcttttgaaa
     2461 cgcttcattt tgtcagaaaa aagcgtattg tttggcgctg acagcttttg ggaaggtgta
     2521 gatttgcctg gagatgcttt gcagatcgtt gtagtcacac gtttaccctt cgataatccg
     2581 cttcgcccga tggtcaaagc taggaacgct tatttagaat cagaggggat caatcctttt
     2641 taccaggaat ccgtacctaa agcagctttg aagttacgcc aagcattagg tcgcttgata
     2701 aggacggaga cagatcgtgg cgtattgctt attttggatc gaagactagt cactgcaaaa
     2761 tatggtgcac ggatcatcca tgcattaccg aaaaaagtac cgatcaaaga gctagctatg
     2821 gaggaaatct atcaggacat ccatgaattc ttaaagaaaa atgaagaagg aagttagagg
     2881 agctgtcttt tttcataatt aaaatctgct ataatgaaaa ggaatgaaga taaaggagcg
     2941 acgacccttg aagaaaaaac agacaaagga aaaaacgatt aatcgcgtgt tacttggctt
     3001 gatcgtattt ttattagcgg tcatcgtgat cagctcgatt ttttacttgc gttccagtcg
     3061 tccggcggtg caggcgaaga aagaagcagt agaaatcgca aagaaatatg caaatcttga
     3121 ggaagccgat catttttatt ggtttactcg aaagaagaca tacttttcac tgacaggtac
     3181 aaatgataaa ggaaaagaaa tcgccgttat cattcctaaa tctggtgaaa aagtaaaagt
     3241 attggatcaa acaaagggac tgactgaaaa cgaagcaaaa cagacaattg ctgcggccca
     3301 tcctgaaatc caaatcgaaa aagctgcttt agggatgtat gatgatcagc ctgtgtggga
     3361 agtagtagga aaagaaacaa atgggaaact gaattattac ctgattggct ttgaatctgg
     3421 agatgaagtc aagacaatca agggaattta aaaggtaaag gaatgaatgg gatggagtta
     3481 tcaaaaagaa caaaacgatt agaaccgtct gtcactttgg cagctgcggc aaaggccaag
     3541 gcattaaaag caaaaggcag agatgtgctg agtttgactg tgggagaacc ggattttgcg
     3601 acaccagaaa acatccaaga agcagcaatc gaagcaatcc gcaatgggaa agctagctat
     3661 tatacaccaa cagcaggaat cccagagctt cgacaggcaa tcgttgatta tctgaagaaa
     3721 aactatggac ttgtctatga accttcacaa acagtcgtaa cagacggagc gaaatttgct
     3781 ttgtataccc ttttccaaac gatccttgac ccgcaagatg aagtcatcat tcctgtgcct
     3841 tactgggtca gttacggtga gcaagtaaaa ctggcagaag gacttcctgt ctttgtgaaa
     3901 ggggaagaat ccaatagctg gaaagttact gttgagcagc tagaacaagc acgttcagaa
     3961 aaaacaaaag ccgtaatcat caattctcca tcgaatccga ctggaatgat ttatagcaag
     4021 aatgaactgc aggcaatcgg tgaatgggca gtaaaaaatg atattttgat agttgctgat
     4081 gatatttatg gtcgtttagt ttataatggc aatgagttta ctccaattgc aacgatttca
     4141 gaagcaatca aaaatcagac catcatcatc aacggcgtgt ctaaaacata tgcgatgaca
     4201 ggctggcgca ttggttatgc ggtggggaat tctgagatca tcaatggaat gatcgctgtt
     4261 gcttcccagt caaccagtaa tccgacagca gtcagtcaat atgcagctgt tgaagcattg
     4321 aaaggcgagc aagatacagt ggaagaaatg cggaacgcct ttgaagaacg cctgaatacg
     4381 ttatatccgc ttgtggcaga actgccgggt gtttctcttg aaaagccgca aggagctttt
     4441 tatctttttc ctaatgtaaa agaaacgcta cgcatgtgta aatatgaaaa tgtcacacaa
     4501 tgggtagaag atcttttaga agaaacaggg gtagcgcttg tgactggcga aggctttggg
     4561 gcaccagaaa atgtccgcat gagttatgct actgatcgcg ctacgttaga agaagcggta
     4621 cgcagaatca agcaatttat tgagagtaaa agtcaaaatt aatcctgaag aaattcaagg
     4681 aatataaaag gagagtcata cgtggaacaa attcaaatca tcgattcgaa aaaccatgtg
     4741 ggagaaacag taacaatcgg cgcttgggtc gcaaataagc gatcaagcgg aaaaatcgca
     4801 tttttacaat taagagacgg aacagccttt ttccaaggtg tagttgtaaa aagcgaagtg
     4861 ccggaagaag ttttccaaac agctaaaaat ctacaccaag aaacatccgt gttagtaact
     4921 ggagaaatcc gtgaagacag tcgttcaaaa tttggttatg aaatcggaat tacaaatgtg
     4981 gaagtggtaa gcgagagcca cgattatccg atcacaccaa aagaacacgg aacagacttc
     5041 ttgatggatc atcgtcattt atggctgcgt tcttcaagac aacatgcgat tatgcagatc
     5101 agaaatgaaa tcattcgtgc aacgtatgaa ttctttaatc aacatcattt tgtcaaaatc
     5161 gatccgccga tcttgactgg ttctgcacca gaaggcacta cggatctatt cgaaacaaat
     5221 tactttgatc aaaaagctta tttatctcaa agtggccaat tatacatgga agctgctgct
     5281 atggctttcg gaaaagtctt ttcattcggt ccgactttcc gtgctgaaaa atcaaaaaca
     5341 cgacgtcatt tgatcgaatt ctggatgatc gaaccagaaa tggctttcac tcatcaagaa
     5401 gaaagtttag aagtacagga acaatatgta gcattcttag tacaaaatgt tttagatcat
     5461 tgcgaatacg cattagatgt actaggacga gacaaagaag tcttaaaaac ttatacaaaa
     5521 ttgccattcc ctcgtattac ttacgatgat gcaatcgaat tactgaagaa aaatggattt
     5581 gatgacatcg aatggggcga agactttggt tcacctcatg aaacgttcat tgcgaattca
     5641 ttcgaacagc ctgtctttat cctaaactat ccaaaagcca tcaagccatt ctacatgaaa
     5701 ccacatccaa caagagaaga cgtggtgatc tgtgcagata tgatcgcacc agaaggttac
     5761 ggtgaaatta ttggcggaag cgaacgggca acagactatg atttcttgct agaacaaatc
     5821 cgtaatcacg gtttggatga aaaagaatat tcatggtatc ttgatctacg taaatacggt
     5881 tctgttccgc actctggttt tggtctaggc cttgaacgaa cagtcacttg gattgctggt
     5941 atcgaccatg tgcgtgaagc tattccattc ccacgtttgt tgaaccgaat ttatccataa
     6001 gaggttgtga aatcagtgcc ttgacctgag tattagagaa acaaaacgga aaaatagctt
     6061 ctcatatttt accgtttttt tagctaatat cgagggtcag ctgattgaac accgtttata
     6121 tcaagaggtt gtgcgcctgc cgttcagctc cgagtcacaa ggagtaattt caaaaaacag
     6181 tttttcatgt ttgatgacta ttgtgacttg tgaccgagga gttggccgga gagcaccgtt
     6241 tattctaaaa aagaactgcg aactctcgca gttctttttt ttaaatacgg gataaaggaa
     6301 gtttccagca gacaagagaa gaaagcaaaa gaaattgcta tttgattcac aaggttctat
     6361 aacgaaatcg caatcaatca aacatttaca aagaaggtaa ttcaaatgga aatctaattt
     6421 gatgatgctt ctgctgttga aataaagcat catctagcac ctgaaaacaa actaatagta
     6481 acattcgaag atggagtagg tccgtatttt cagcatgcaa taatccatat gtaagttcaa
     6541 ttcacccttg aaatcatcgg accagataaa gttatgacca atctatccca agcaatctag
     6601 aagagatatt agtaaaggga catttactag aagtcttaga tgagcctata aatatatgtt
     6661 ttgatggcgt catcagtggt ctgattgacg gaagcttggg tatgatcgat ctctctggac
     6721 caaacaacga aggaatcaag gggaatccgg cacgttaaga aaaaaatagc ataaaaaact
     6781 agacacttga tgagcgttca ttcaattgtt tgaagggact aggctgatgt cattttttat
     6841 acatatattt tctctttcgt cttgataggg cttatgggat aatataagga agaaaatcat
     6901 cgttttattc aaaaaggagt ttttgacaaa tgaaaaaacg tatattattt atcggtgata
     6961 gcattacaga cgcaggaaga gaccgagcag aagcaactga tctaggtaaa ggttatccac
     7021 ttttgattgc cggaaaacta atcgcccaat atccaacgat ggaatttgaa tgcatgaacc
     7081 gtgggatagg aggagacaaa attgcagatc tgcaagtacg ctggcaagaa gattgtttag
     7141 ctttacaacc tgactatgta tcgattttga tcggaatcaa tgatacctgg cataatacta
     7201 gcgatcaggc tatattcgga actgagaaat ctgctcagca atttgaatcc gtttatcgaa
     7261 aattactaaa tgaacttcaa acagcggaaa tctgcaacat catcttgatg gagccgtttg
     7321 tacttcctat aaccgacgac cgtcatggct ggcgtaaaga cttagaccct aaaatccaaa
     7381 ttgttcgtaa acttgctaag gaatatggcg cattgctggt tcctttagat ggtatattca
     7441 atgctttagg gattgcttat ggtttttcga aatatacaag agaagatggg gtccacccaa
     7501 cgattggtgg acatgagatc attgcacaaa gctggataga tgcaattgcc gcagtcgatt
     7561 tttttagtgg agataaaaat gagcgaaaga aaagtgaaaa atgatggaaa taaggtgggc
     7621 agtaaaagaa gatttacctc aaatcaatca gctgattact gatcatccag aatcattcgt
     7681 aaaagcaaaa acggcagctg acctaaatga taagaataaa ctattgctcg ttgctgtaac
     7741 aaaagaaaaa cggattatcg gatttgcgca agcggacgtg caacagtcag aagaacgatt
     7801 ggatcagcga ccatcaggaa aactaatcca acacacatta gtaacaaaag aaaatacgga
     7861 agaaatccaa aaaaaatttg cagaatattt gatgctggaa gctaaaaaaa gaagaataaa
     7921 atcatttttt gcccagtttt aatcaaaaac agtaatagaa ggagaaatat aatgagttgt
     7981 ttaggaaatg tcatctggtt tatattcggc ggactaatcg gtggtcttag ctggttagca
     8041 gcggggatac tttggtgtat cacgatcata ggtatcccaa tcggtatgca atgttttaag
     8101 atcgcctccc tttcttttgc gccttttggc aaagaagtaa tttatcacca gtctggcata
     8161 tcattgatcg ttaatatcat ctggctgatc atttcaggcc taccaattgc tctcgcacat
     8221 gtcgtcagcg gcatccttct atgtatcacg atcataggga taccttttgc caagcaatct
     8281 ttcaaacttg ctcgattggc gttgatgcca ttcggtgcag aaattgtata aaaagagaat
     8341 aataaaggtt agaaaacgca tagagtcagg tgggatacat gtatttcacc tgactctatg
     8401 tgttttcctg tataagttct cccatgtgac ttttacgtct tttatttata tgggattact
     8461 gtttatggaa agttgaaata attttcatta aagaactctt gctatatttt tgaaagctta
     8521 gtggagcttc gaatatctgg gaaggacatt ttgcagggat tgaaaaaaga tattgtccta
     8581 tcgaaaaatt aatgaattta gacaaattgc cagcaacagg cttcaaactt agttgctatc
     8641 ctgtcaagat caagaaggca agtgcgggtt ggataagagc agtggcaatg atcgaaaaga
     8701 aaaagaaaga ataagccaaa acatctgtat ggaagaaatt ttccgatgca gatgtttttc
     8761 attttttctt tcggatacct tgacatatga ataaccgttc atttataatt agttatgaag
     8821 agatattcat atgttgaggc gaggaggtca ttaaaatgaa aagttacaga ttagaaggtt
     8881 tagattgtgc gaactgtgca atgaaaatcg aaaaaggagt tcagaagatc aatggagtca
     8941 aggaagcaac ggtaaacttc acttctggaa aactaacgat tgacgcagag gaagatcatt
     9001 tggctacgat tgaacaagaa ataaaaaaag tagtgaagga attagaacca gatgtcaaag
     9061 taacagaaat agataaggaa aaagtatctg aacatggaaa tgaaaaagag agaaatacgc
     9121 tgttccggat tttattttcc cttgcaggta tcgctttatt gctattattt gattttaatg
     9181 aaccaattcg cttgataggg tatttattga tttatctgct gataggatat gatgtagtga
     9241 agaaggcagt gatgaatatc gtcaaaggaa aaatctttga tgagaatttt cttatgtctg
     9301 ttgctacgat tggcgctatg ttgatcggtg aatatccaga agccgtagca gtgatgctat
     9361 tttatcaaat cggcgagtat ttccaaggat tggcagtcag tcattcaaga aaatcgattc
     9421 gcgaattgat ggcgatccgt ccagaaacag ctcacgtgca gacgacggaa ggattgatga
     9481 ccgtgaaccc tgaagacgtg cagatcggtc agtttgtact tgtgaagcct ggtgaacgtg
     9541 taccgttaga tggaacgatc atcgaaggag aatcattagt cgatacgtca gcacttacag
     9601 gagaatcagt ccctaaatct gtatatgttg gtgaaacagt attaagtgga tttatcaata
     9661 aaaataaacc atttttagtt caagtagaaa aatcttatga aaattctact atcagcaaat
     9721 tattagaatt agtagaaaat gccagcagta aaaaagcacc agctgaaaat ttcattacta
     9781 aattcgcgcg ctattacaca ccagtcgttg taggattggc cgttttatta gctgttttac
     9841 ctccacttgt tgtttctgga gcggcgtttt ctgaatggat ctatcgagca ttgacatttt
     9901 tagtgatctc atgtccatgt gcattagtga tctccgtacc ccttagtttc tttggcggta
     9961 tcggaggagc aagtaaaatc ggtgtattag taaaaggttc aaattacttg gagttgcttg
    10021 cacaaactga gacagtggta ttcgataaaa ccggcacatt aacgaaaggt gacttttcga
    10081 tccagacgat cgatacaaaa atcgatccaa agatattcat gcaatatgtt gcgagtgcag
    10141 aacagttttc tacacatccg attgctcaat ctgttttaga aggctacgca ggtccgcttt
    10201 taccaacagc taatatccaa gaatttgcag gtgaagggat cttagctgaa gttgatggca
    10261 aacaagtatt agcaggtaat cacaaattga tggaaagatt tgaaatctct tttccttcaa
    10321 gtcaagaaat cggtacattg ctttatctag cgatcgatca aagttacagt ggttatcttg
    10381 ttattgcaga taccttgaaa gaagatgccg tagacgcatt ggttcaatta aaaaaggctg
    10441 gtgtgaagaa cacagtcatg ttgacgggcg attcgaaaaa aattgctgat catatcggga
    10501 agcaagtagg cgtggacaag atatatagcg aattgcttcc agaagataaa gtgcagcggt
    10561 tagaggaaat cttacaaaga aacaataaaa agaccgcatt tgtcggagat ggaatcaacg
    10621 atgcaccggt gctagcaaga gcagatgtag gaatcgcaat gggtggattg ggaagcgatg
    10681 ctgcaattga agcagcagat gtagtcatca tgaatgatca accatcgaag attgcagaag
    10741 caatccattt agcaaagaaa acattgaaaa tcgtcaaaca gaacattgtc tttgctattg
    10801 ggataaaaat tttggtactt gccttaggtg cttttggttt tgcatcaatg ggagatgcag
    10861 tatttgcaga tgttggggtg acagtattag ctgttttgaa tgccatgcga agcttgcatg
    10921 taaaaaataa acgttgatca atgaagagga cgaatgaacg tcctcttttt tttatatcct
    10981 tttcttaatg aaaaatgtaa agaaaataga taggattata aaataactaa tgtttttaat
    11041 tttgcagaaa attcaaaata gcttgaaatt caataaggta aatgaaataa aagaaaataa
    11101 cttatttttt tgatggaaaa aatatgaaaa aacgatgtgt attaaataaa agaatacaca
    11161 cataaaataa cactgtcttg taagtttgtt aaaaattgaa tatgattaca tctggataac
    11221 aaatttttat cataaaggag agaacgaatg aacaacaaac aattacgctg gtttactgtt
    11281 gcgttaattg catttaacat ggtttggggc atggggaatg tagttaataa ctatgctcag
    11341 caaggagtat cagttgtcac ctcttggcta ttgattttgg ccatttattt tattccatac
    11401 gcattgatcg ttggacaatt agggtcagcc ttcaaggata gtaaaggagg cgtcagttca
    11461 tgggtcgaaa atacgacatc taataaacga ctggcatact atgccgcttg gacttactgg
    11521 gtcgtccata ttccttattt ggcacaaaag cctcaagcaa tcctgattgc tggcggttgg
    11581 gcagtccaag gaaatggaaa tatcgtaaat acgatgtcag tacaaatggt agcagttatt
    11641 tcacttatta tatttcttgc ctttttatat ttatcaacaa aaggactttc tactttgaaa
    11701 gtgattggcg gactggccgg aacagcgatg ttcgtcatgt cgatcttatt tattctttta
    11761 gctgtaacgg caccgttcat caatccaacg atggaatttg ccacaccaca tatgaatcaa
    11821 gtgaaaacat atattccaac atttgatttc agttatttca caaccgtttc gatgctagta
    11881 tttgcagttg gaggagcgga aaaaatatcc ccttatgtca actctacaag aaatcctgca
    11941 aaggaatttc ctaaagggat gatcttctta gcagcaatgg tagggatttg tgctgtatta
    12001 ggctcagtcg caatgggtat gctgtttgct agcgataata ttcctaaaga cttgatggca
    12061 aatggggcat acagtgcttt tcaaatttta ggtaattact atggtatcgg taactcattg
    12121 atgatcattt acgcattgac aaacatgatt ggacaaatct ccgcattagc cttttcaatt
    12181 gatgcaccac taaaaatctt gttagcagat gcggatccag aatttgtacc aaactggcta
    12241 cgtaaacgta atcgtaaagg tacattggtg aatggttatc ttctgacagg tatactagta
    12301 ggaatcatta ttttgttgcc gatctttggt atcaaagata tgaatgaatt agtaaaatgg
    12361 ttgacgaact tgaactcagt tgtcatgcca atgcgttacc tatgggtgtt cttggcatat
    12421 atgatgttga ataaagctta taagaaattc aattctgaat ataaatttgt taaaaatcca
    12481 aaaatcggtt ttatctttgg tgcttggtgc tttgccttca ctgcgtttgc atgtatccta
    12541 ggaatggtgc caaaagtaga ttatactgct gatcctaaag catggtggtt ccaattattc
    12601 acgaatatca tcacaccaat tgtcttgatc ttattaggta tgatcttgcc agcaattgct
    12661 cgtcgagaca aaaacaaaga aatcactgaa ccagaaacag tggttcagcc ttaaaataga
    12721 aatacttgtt acaagaggtt gtgacagaag tggtcagctt caagaaataa gaaggaattt
    12781 acgaaaattg cttctcaaat ttttgtgaag tttcggcttg tttttcgcag aagctacttc
    12841 tggaacaccg tgaatcagag gttgtgaaaa agctgtcctg catcaagtaa taagaacagc
    12901 caaacaaaaa tagcccctca tatttttcgt tttgctgggc ttattaccgc agatgcaagc
    12961 ttttgaacac cgtttaagaa agaggtagtg agcctgccgt ttaactccga gtcacaagga
    13021 gcaatttcaa aaaacaactt ctcatgtttg ttgactattg tgccttgtga ccgaggtgtt
    13081 ggcaggagaa caccgtttaa ggaagaggtt gtaaaatcag cgatttgacc tgagtattag
    13141 aggaacaaac gaaaaaatag ctcctcatat tttgccgttt tttgagttaa tgctgaaggt
    13201 cagctgattg aacaccattt attcgaaaca agggactttg acacgacttt tgtcacagtc
    13261 ccttgttttt ttgcggcgtt ataagtggta tgatcgaacc aaattccaaa gagaagtgag
    13321 ggagaagaat gaagatcatc gtgattggac aaagtgggtc gggaaaatcg accctcgcaa
    13381 ggaagatcaa agaaatcacc gactttccgc tactgccgct agacctttta tggcatacaa
    13441 cagactacag tattcaggca aaaaagtggt ttttgcaaga acagcaatcg tttatggtat
    13501 ctaatccgtc atggattgtt gaaggaaatt atacttctac attagaggaa aggattaaag
    13561 aagcagataa gatcatttgg cttaaagtgc cgcgttatct cgccatctac cgagtagttt
    13621 ggcgttctct aaaaagaaag ataaacaaaa aatctcggcc agatatgcct gaatcatttt
    13681 cagagaaact aaacagggaa tacttagaat ttttatcttt tatctggcat tttgaagaaa
    13741 acaatgaacc gaaaatacag cagctgatcc aagtagctaa tgcaagaaat aaactgatca
    13801 tccttaaaac aagacgagag aaacaagaat ttttaactaa attgaaaata gagagcaaaa
    13861 ataattgaca gtttttgttt acaagcgtaa tctgtattca taagctaatg attacatttg
    13921 taaacgaaag gtgtgaaata aatggaaaaa gtcaaaacgc cagtaaagat cagtgattca
    13981 gagtgggaga tcatgcgtgt tatttggaca cttggacaga cgacagccca agaaatcacg
    14041 cagatcttag ctgattcgat ggattggaaa ccagcaacga tcaaaacttt gctgggacgt
    14101 ttggtaaaaa aagaagtgat ctggacagaa caagaaggaa aaaaattcat ttatcatcca
    14161 gctgtctcgg agatggaaac agttcgcagt gcgacggaaa atcttttttc ccatatctgt
    14221 gcaaaaagga ttggagagac gattgcggat ctagtagaag aagccacttt gactcaagaa
    14281 gatatcaatg agattttgaa acaactggaa caaaagcaac cagtagatac gatcgaatgt
    14341 aactgtatcc caggtcaatg tgaatgtaaa caacatcaat aggaggaaga aaaaatgaaa
    14401 caacaatttt caatcgaagg tatgagctgc aatcattgtg cagcaagagt agaagaaaca
    14461 gtaagcgcac ttgacggcgt gcaaaaagtg aaagtaaatt tgaaaaaagc aaacggtacg
    14521 gtcaagtttg atgaaacaaa agttcaatcc gaaaagattt gtcaagcaat caatggattg
    14581 ggttataaag cagaggtgat ttgatggcaa cagcagaaac caaaatggat acgttcgtca
    14641 ttacaggtat gacttgtgca aattgttctg ctaggatcga aaaagagctg aacggacaac
    14701 ctggtgtggt caatgccaca gtcaacttgg ccactgaaaa agcaagtgtc aaatatgaag
    14761 ggacgaccac tgaaaaatta atccaaagcg tagaaaacat cggttatggt gcaattttgt
    14821 acgatgaagc ccacaaacaa aaaattgcag aagaaaagca agcgtatttg aaaaaaatgc
    14881 tattcgatct tatattgagt acggttttga ctttgccgtt gatgttgtca atgattgcta
    14941 tgatgttagg aagccatgcg gcgattgttc acttttttca ttttccaatc gtccagttag
    15001 tgctgtctgc tcctgtccaa ttttatgtcg gtgctcgttt ttataaaggt gcgtaccatg
    15061 caatcaagac gaaagcacca aatatggatg tattggtagc aattggaaca tcggctgcct
    15121 ttgcattgag catttacaac ggatttttcc gtggacaccc ccaagatctt tattttgaaa
    15181 gcagcagtat gatcatcacg ctgattttgc tcggcaaata tttggaacat acagcaaaaa
    15241 cgaaaacagg taatgcaatc aaacaattga tgtctcttca aacaaaaacc gcccaagtga
    15301 taagaaacgg gaaagaagaa acgttagcga ttgaagaagt agtcgttggt gatcaactag
    15361 tcatccgtcc tggtgagcag attccagcag atggtcgaat tatttcagga agcagtgcga
    15421 tagatgaaag tatgcttact ggtgaaaatc ttcctgtaga aaagaatccg gatgacacgc
    15481 tttttggcgg gacaatcaat acgaatggtc tgctacacat ggaagtcaca caagtcggca
    15541 agcagacagt attagcgcaa atcattcaaa tggtggaaga tgctcaaggg agcaaagccc
    15601 caatccaaaa aatcgcagat cggatctcag ggatttttgt tccgatcgta ttagtcatcg
    15661 cgtttatcac gctcatagct acaggtttga tcactggtga ttggcaactc gcattgatcc
    15721 atagtgtctc tgtattagtc attgcgtgtc catgtgcatt aggtttagcg accccaacag
    15781 ctattatggt aggaacgggt gttggtgcac gaaatggaat tttaattaaa ggcggagaag
    15841 cattagaagc agctgctcac ttagacagca ttgttttgga taaaactgga acgattacag
    15901 aaggaaagcc caaagttaca gatctagtcg gttcaaaaga agtcctatct attttttata
    15961 ctttagaaca agcttctgaa catccactag gtaaagcaat cgtggaatac ggaaaactgc
    16021 aagaagcagc aacatacgat atgattgatt ttacagccca cccaggtgct gggatcagcg
    16081 gtacgattaa tggagtacgc tattttgcgg gtacacgtaa acgattaatt gaattgaacc
    16141 tatcatttga tgaataccaa gaacacgcgt tagaattaga acagcaggga aaaacagtca
    16201 tgtttttagc tgatgaaaag caagtgatcg ggtggattgc cgtggctgat caaatcaaac
    16261 tagaagccaa acaagcaatc aagcagctcc agaataaagg attagatgtt tttatgctga
    16321 caggagacaa caaactggca gccgaaacga ttggtaaaca agttggtatt gatccaaagc
    16381 atatctttgc tgaagtactt ccagaggata aagcagccta cgtagaaaaa cttcagaaag
    16441 atggcaaaaa agtcggtatg gcaggcgatg gaatcaatga tgcaccggcc ttagcattag
    16501 ctgatgtcgg tatggcaatg ggaagtggaa cggacattgc gatggaaaca gccgatgtga
    16561 cgctgatgaa tagcagtttg gcatccattg cacaaacaat cgagttgtct aggttgacat
    16621 tgagaaaaat caaacaaaat cttttctggg cttttgtcta taatacgatt ggtattcctt
    16681 ttgccgcact aggctttttg aatccaatca ttgcaggagg agcgatggcg tttagttccg
    16741 tcagtgtatt gttgaactcc ctgagcttaa atcgacacat gaaaaagtaa gagaagggat
    16801 ggagtaaaaa tgaatgggaa cgatatggag aaaaaacatg agcataaaaa agaagtagta
    16861 aacaaagaaa gtacagaatc tcatgaaaaa cagatggaga tgaaacatga ccatagtcag
    16921 atggatcatt ccatgcacat gggacataac catggagata tagcaaacag caaacaaatg
    16981 gaccattcga tgcacatgga tcacgaacac ggcggcatgg atcattccat gcacatgggg
    17041 aatttcaaac aaaaattttg gctatcgctt atcctagcta tcccaatcat tcttttttca
    17101 ccaatgatgg gaatggaatt tccatttcaa gtaacgtttc ctggttctga ttggctcgta
    17161 ttgatcttag caactatact atttatctat ggcggtcagc catttttaag tggagctaag
    17221 atggaattga aacaaaaaag tcctgctatg atgacactga tcgcgatggg gattacagtt
    17281 gcatatattt atagtgtcta ttcgtttatc gcaaatctgc tcaatccaca tacacacgtc
    17341 atggatttct tctgggaatt ggctactttg atcgttatta tgctactagg tcactggatt
    17401 gaaatgaatg ctgtgtcgaa tgccagcaat gctttacaaa aactagcaga attactgcca
    17461 gaatcagtga aacgcttgac gaaagatgga aaagaagaga cagtttcatt gaaagaagta
    17521 aacgaaggtg atcgtttgat cgtccggtct ggtgataaaa tgccaacaga tggtgtaatc
    17581 ttgaaaggtg aaacaattgt tgacgaatca gctgtgactg gcgaatcaag aggaatcaaa
    17641 aaacaagcca atgacaaagt gattggcggt tctatcaatg gggatggaac gatcgaaatc
    17701 gaagtaactg gaactggtga aaatggttat ctagcgaagg ttatggaaat ggtgcgaaaa
    17761 gcacaaggag aaaaatccaa gctagagtca ttatctgaca aagtggcaaa atggctgttt
    17821 tatgtcgcat taattgtggg tatcctggca ttcatcgcct ggttgttctt gacagatctt
    17881 cctaatgcat tagaacgtat ggtaacagtc tttatcatcg cctgtcctca tgctctaggt
    17941 ttagctatcc cattagttgt tgctcgctcc acatcaatag cagctaaaaa cggattactt
    18001 ttgaaaaacc gcaatgcact ggagcaagcc aatgatctag atgtgatcat gctggacaaa
    18061 acaggaacac taacagaagg aaaatttact gtaacgggtg tcgaagtact tgatgatgcg
    18121 ttcaataaaa atgaaatcct tcaatatcta ggagccttgg aagcgaatgc caatcatcca
    18181 ttggctgttg gcattatgaa ttatttgaaa gaacatgaaa tcaagcctta tcaagctgaa
    18241 aatctaaaaa atctttcagg agtcgggcta gaggcaacag tcaaaaaaca acaagtgaaa
    18301 atagttaatg aaaaagaagt tgagcgtctc ggattaaacg tagaacaagc attattgaaa
    18361 ccttaccaag aacaaggaaa taccatcagc ttcctgattt tagaaaatca tctagctgca
    18421 atcgttgctt taggtgacgt agtaaaaaca gaagcaaaag aatttatccg aacattgaaa
    18481 gaaagaaaaa tcactcctgt catgcttact ggtgacaata aaaacgctgc ccaagcagta
    18541 gcagattatt tagggatcga agaatattat ggcggtttat taccagatga taaagaagct
    18601 gttgtccaga aataccttga ccaagggaaa aaagtaatca tggtgggtga tgggatcaat
    18661 gatgcgccaa gtttagcccg tgcttcaatc gggatggcaa tcggtgcagg gacagatatc
    18721 gcaatcgatt ctgcggatgt cgtattgaca aacagcgatc caaaagatat tttgcatttt
    18781 cttgatctag ccaagcaaac gcgaaagaaa atgatccaga acctctggtg gggggcaggt
    18841 tacaatattc ttgcaattcc gctagcagcc ggaattcttg cgccaattgg tatcatatta
    18901 agtccagcag ttggtgctgt cttgatgtcg ttaagtacgg tagttgtagc tctaaatgct
    18961 ttgacattga aaatcaaata ataatgaaaa aaggggctct ttgtcaataa ggactgatgg
    19021 gttgtacaaa atcaaatctg ggtcagaatg aacctcattc tggctcagat tttttgttat
    19081 cttactttga ttaattgatt gatcaaaaag attctaattc tcatgttctc aaatgattta
    19141 aatccgtagg atactc
//
LOCUS       DAXLPC010000051        18528 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.051, whole genome shotgun sequence.
ACCESSION   DAXLPC010000051 DAXLPC010000000
VERSION     DAXLPC010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.051"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            94..261
                     /locus_tag="ACF3UE_001707"
     CDS             94..261
                     /locus_tag="ACF3UE_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFD3635112.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(323..2134)
                     /locus_tag="ACF3UE_001708"
     CDS             complement(323..2134)
                     /locus_tag="ACF3UE_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFD3635113.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(2131..2496)
                     /locus_tag="ACF3UE_001709"
     CDS             complement(2131..2496)
                     /locus_tag="ACF3UE_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFD3635114.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(2659..3054)
                     /locus_tag="ACF3UE_001710"
     CDS             complement(2659..3054)
                     /locus_tag="ACF3UE_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFD3635115.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(3072..4034)
                     /locus_tag="ACF3UE_001711"
     CDS             complement(3072..4034)
                     /locus_tag="ACF3UE_001711"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFD3635116.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(4034..4246)
                     /locus_tag="ACF3UE_001712"
     CDS             complement(4034..4246)
                     /locus_tag="ACF3UE_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFD3635117.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(4267..4965)
                     /locus_tag="ACF3UE_001713"
     CDS             complement(4267..4965)
                     /locus_tag="ACF3UE_001713"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFD3635118.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(4985..5527)
                     /locus_tag="ACF3UE_001714"
     CDS             complement(4985..5527)
                     /locus_tag="ACF3UE_001714"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFD3635119.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(5659..6663)
                     /locus_tag="ACF3UE_001715"
     CDS             complement(5659..6663)
                     /locus_tag="ACF3UE_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFD3635120.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(6660..7649)
                     /locus_tag="ACF3UE_001716"
     CDS             complement(6660..7649)
                     /locus_tag="ACF3UE_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFD3635121.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(7646..8452)
                     /locus_tag="ACF3UE_001717"
     CDS             complement(7646..8452)
                     /locus_tag="ACF3UE_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635122.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            8618..9574
                     /locus_tag="ACF3UE_001718"
     CDS             8618..9574
                     /locus_tag="ACF3UE_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3635123.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(9651..10169)
                     /locus_tag="ACF3UE_001719"
     CDS             complement(9651..10169)
                     /locus_tag="ACF3UE_001719"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFD3635124.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(10257..10406)
                     /gene="rpmG"
                     /locus_tag="ACF3UE_001720"
     CDS             complement(10257..10406)
                     /gene="rpmG"
                     /locus_tag="ACF3UE_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFD3635125.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            10634..11080
                     /locus_tag="ACF3UE_001721"
     CDS             10634..11080
                     /locus_tag="ACF3UE_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFD3635126.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(11275..13170)
                     /gene="asnB"
                     /locus_tag="ACF3UE_001722"
     CDS             complement(11275..13170)
                     /gene="asnB"
                     /locus_tag="ACF3UE_001722"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFD3635127.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEKWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(13495..14469)
                     /gene="bsh"
                     /locus_tag="ACF3UE_001723"
     CDS             complement(13495..14469)
                     /gene="bsh"
                     /locus_tag="ACF3UE_001723"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFD3635128.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(14803..14890)
                     /locus_tag="ACF3UE_001724"
     tRNA            complement(14803..14890)
                     /locus_tag="ACF3UE_001724"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14856..14858),aa:Ser,seq:cga)
     gene            complement(15035..15601)
                     /locus_tag="ACF3UE_001725"
     CDS             complement(15035..15601)
                     /locus_tag="ACF3UE_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3635129.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            15857..17187
                     /locus_tag="ACF3UE_001726"
                     /pseudo
     CDS             15857..17187
                     /locus_tag="ACF3UE_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
     gene            17153..17503
                     /locus_tag="ACF3UE_001727"
     CDS             17153..17503
                     /locus_tag="ACF3UE_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635130.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(17595..18014)
                     /locus_tag="ACF3UE_001728"
                     /pseudo
     CDS             complement(17595..18014)
                     /locus_tag="ACF3UE_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(18015..18359)
                     /locus_tag="ACF3UE_001729"
     CDS             complement(18015..18359)
                     /locus_tag="ACF3UE_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFD3635131.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
BASE COUNT         5614 a         3822 c         3135 g         5957 t
ORIGIN      
        1 tttttgcaaa ggtttacaaa caaacgtaaa actagccttt ttttctcttt tgttccataa
       61 tagatataac aaataataaa tgaggtggat tcaatgaaaa aatttgtatc tggaatatta
      121 gtaggaagtc tggcaacagc cgctgccgtt gctggtttgg ttgcttctgt gaaaaaaaca
      181 gtgatcgatc caattgacga aaaagaagca atgatcgaag aaaaccgtaa aaaagcaatg
      241 cgtaaacgcg tttctcgtta ataattattt aaaaatacgc atgaagactt tctaaaaaac
      301 agataagtca tcatgcgtat ttttatttgt cagtcaatat aagttgtgct attttatctg
      361 cctgtctcag attccatgga tctgtataag gtctagctac tgctgcagtt agccaatcca
      421 caccttcaac aggtattcca tagcaataaa agtcagactg gatttcccct gaagcatcaa
      481 tcacgcgatt cgtacctcgc tcaacatcta tagcttctga atgataactt cctgtattat
      541 ctgaaaatga aaaagggcga acaagtttgt tttccttcaa attttttatg acaggattac
      601 ttgaacgaga aaagcttgtt tgtggcaatc gagcttcaat caaatagcga ctgctgattt
      661 ctttatcttg tagagaaata acatagcggt tgtgcttttg ctgaatatca aatggcggtt
      721 cgatcaaatg aaaaataccc gcatctatca gtgctgctaa ttctttcgtc cgaatgattg
      781 gcggaccgat cgttaaaaag ctatttagat gagtaaacca tccccatagt atttctttgt
      841 attccttagc agaaaaaacg tgccattcaa tagcctgccg gattggatca cgccagtctt
      901 ttaatgcatc aaatgttgaa gcaaatgctc ctgtgcaatt gcctttttcc gcttctttta
      961 tctgcccttc aataaatatt cggctagctt ctgaaaaggg ctcattctga taggcaagag
     1021 gagtttctaa atacgaccaa tcccatctat aagggattag tgctggatgc tttccgagac
     1081 actcctctga agagagggag agaaaatcat gctcaaaatt tttctttgga atcggcaagt
     1141 gatattcttc gatgattttc ttgtaataaa acaactcaac gtcttttttc agatagtcaa
     1201 aaaatgtttc gccagtcaaa aatcccgact gatgccattg ctccaggttt tcttttgtta
     1261 gtaaccgtgg ccatgccatt gctccgcctt gcttttgatt tcttcctcga gggtaataag
     1321 ggagccccct tcttgatcca ctgtatacaa tcggttcctt gcctgatgga tgatagacca
     1381 gttttccctt ttcgttctcg aagcgccctc ctcttgatac tgtaaacaat ccgacataat
     1441 caaaaaaact taagcctaga cctcttaaaa agacattttc tttaggcggt atcttcgaaa
     1501 gatctacatc tgcaggatta gaaggaagct gatacagtaa aacatttttc tttgcgtagt
     1561 ctacccacac tctttcttct tctgtctcat cattttccca gtgaccgctt gctaaaacaa
     1621 gctgatcgat agaatagctt tgctgatctg tctgtaaaag ataaccatct tttcttttgc
     1681 ttactttttt tactaaagaa taaacaaact gaatagaagc tggaaattct tcttgcaact
     1741 ttgagaaaaa ccagcgttga tagagtccgt ataaacatcg agtagattgc tgatcttttt
     1801 ccagacgatt gatttcttct ataattagtt gcttattttt ggttaccgtc tgttcgatat
     1861 aatctgtagc aggtccttta ctccattgaa acaagttggg tccctgtgtt accaatcctc
     1921 cactggacaa tgtttcatct gtaaaaagcg tcacttgttg agaaacagaa ttcattaata
     1981 actccggtgg ctgattcaac cgccaaactc gacctccagg accattggga tcgaaaagaa
     2041 aaagttcaag agaatgtctg tcctgattat tatggagaat cctttctgct acacttaatc
     2101 ctctaggtcc ggcaccaatg atccctattt tcatttgcat gcctccattt cgataaattt
     2161 tttcaataaa acagcatggt tctgatgttc attttttgca ccataaacaa aagtaatgac
     2221 tggatgttct ttcataagtt gactgagttt aaaaatagct tgcttctttt cttcttcgaa
     2281 aatcaattct tgctggtatt tctttgcaaa tgaagcaaat cgttctggta catggtcaaa
     2341 agttttgcgt gcttcattac taggtgcaat ttctttcaac cacagatcta actgcgcttt
     2401 ttcttttgaa attcctcgtg gccagaatct atccacgagt attctatagc catcctcttt
     2461 ttcagcatca aggtaaacac gttttaattt gatcatagtt gtttccttct ttctaccttt
     2521 tcgcttagct tatatatgta gataatagca caaaataaaa aaaatgaacg gcacaactat
     2581 ccattgcgcc gttcatgtga tcttggtcaa aatctaatga ttgattcggt ttttaaagct
     2641 gtcatacaat catctgtttt atactttttt acttttgatt tttccagacc atccgtcata
     2701 tccaccctta agtaaataaa tctcttgata acctgcttta cgtaatttat ttgctgtacg
     2761 gatgctcaaa cttttctttt gatcgtaaat atagacaggc tggtcttttc gaatagatcc
     2821 taatgaatct ttcaaaacag tgtaagggat gtttcttgca cctaaaatat gcccagcatc
     2881 aaacacatct ttttcgcgaa catcgattac ttgtgctttt ctcattcctt ctcgaaattc
     2941 ttcttctgtc aaagtcgttg ctgaacgttt ggccattact cgtagataga cttcccaaag
     3001 gatgattgca agcacaatca atagcaaaat gatattaatt acccataaaa ccatgtaatg
     3061 cctccgtttt tttaagcaaa tttcaaggct aatgaggcag caccaatgac accagcttca
     3121 ttaccaagct ctgctaattt gatttttgtt gattctctta cttgcgggaa agtaaattct
     3181 ttaaaatatt tctctacacg gctacgtaaa aattctcctg ctgccgatac tcctccacct
     3241 aacacgatac ttgacggatt taatgtattc cccaagtttc cgcaagctaa acctaagtag
     3301 aagcatacgc gatcaacaac catcaatgca aacggatcgt cttcttgagc catttcaaag
     3361 atatctttac ttgttacttc ttctccgttg tctagcattg ctttcagttt tgaatcccct
     3421 gcgtattctt ctgccaagaa acgacctagg cgtaccacac ctgtagcgct agatacagtt
     3481 tctaaacatc cgcgtttacc gcaagtacat tcgaaccctt caggatccac agtgatatgt
     3541 ccgatttctc ctccagctcc gctcacgccg tgaatcaaat ttccgccagc aacgatacct
     3601 ccgccaacac ctgttcctag agtaacgaat acaacgtctg gatcgttttc tccagcacct
     3661 ttccatcgtt cacctaaagc agcaacattc gcgtcattat cgatagcgaa tttgattcct
     3721 gttcctgcct cgatcagttt tttcacaaat tgaacttctg tccagtttaa gttatacgca
     3781 ccaataaccg ttccagcttc gctgtccacg cttcctgggg tacccatgcc gattccgata
     3841 aagtcttcgg ctttcatatt atataaattc aaacgatgat tgattgattc aatgatttca
     3901 ggaacgatat gcttaccatc atccaaaata ttggtatcga tgctccattt ttgctgaatc
     3961 tctccttctg gtgttaaaat tgcaaatttt gctgttgttc cacctaaatc aatcccaata
     4021 atcttcttgt ccattacaaa tttcctttct ttcggctttc ttcaattcgg tgctctcttt
     4081 ttaatatgcg ccacgctgtc atgtatgtat catgatcaat caaacggcta tcatacagat
     4141 tacgcaattc gatagtcatt aattcaatgt catagatgcg tgcacccaca tagataaaga
     4201 tgccaaattt tttgaacagc tgctgtacat catataagct ctccatcttt aagcacttcc
     4261 ttcatattat acaagtaaac catatttttt taaacccagt aaaatacata ttacaaaaag
     4321 aaatacaaaa actagtgtag aaagaatcct ttggtgtatc gaatagcttg tctgttgttt
     4381 cggtagaccc aaaacattcc ctaacactaa tccgccaatt agcccaccga catgtcccca
     4441 aacatctaca gaggtatcca gaagaccaaa aacaaatgtc aacacaataa ataaaagaaa
     4501 atgtctgact agctgctgga tcgctgggtt atgtttaaaa tgaaacccta agataaacaa
     4561 cgcaccgaac aaaccgaata tcgaagtact tgcaccacca gacagaacat tcgcttcgtt
     4621 aaaagcaaag cttgctgtat ttcccattat cccgctgaac atataaatca agaaaaaacg
     4681 ccaatggcca tagattgcct cgatttgctg ccccataaaa tacagtatca gtgagttcat
     4741 tacgaaatgc atcagtccaa aatggatgaa gattggtgtc actaaacgcc accattcatt
     4801 gaagtgaaca agataaggac catacattcc ggcataataa gggatctcaa gtcgcggaaa
     4861 taattccatc atgaggaaga ccgctgtctg tatccctaaa aaagcatagg tccataacgg
     4921 tcgtcttaac catgcacgca attttatttg ctgttgataa ttcatgaaaa cctcccattt
     4981 cattttagtc aataaacaat tgttggatct tctgatcaaa gctctccggt tgccattgtt
     5041 cattcaattg ttcacgaaaa acaaggctac atgttttttt atgaaaatta tttaaatacc
     5101 ggtcgtaata accaccgcca aaaccgattc gataaccggc tctattgtag ataatacctg
     5161 gtacaatgag gagatcgatc atctccggca aatagagctt ctctgattgt ggctcaagaa
     5221 caccaaaact cgaacgtaca agaacggact gttcatccat ttcataaaac gccatctgac
     5281 gtttcggcaa agttttaggt acaactattt tcttttgttc tttttctgct cgttggataa
     5341 ccggctgtgt atccagttca aattcattcg ataaagtcgt ccctatcact tttgctgact
     5401 tccagtactc gctggcgaat agctgtttat agattcgctg ttctttttcc tttttcttgc
     5461 cacttttggc cagatttttc agcttttcga ttcctttccg gcgtaatctt actttcaatt
     5521 ggtccaaaaa ctcacccttc cttctctcat aaaatggtat aggaaaaaaa gaaaaatagc
     5581 aatcgaactt tcaaataaat gcataaatag aataaaaaga agacctagaa atgattggcc
     5641 ttcctttttt aatgaatttc aactgttcag cgcgtgtttt tgtctgataa aaagtgcata
     5701 cagaaaatat ggcgcaccaa aaagggcaat caaaattcct gtaggtactt ccccacttag
     5761 tagaatcact ctagcaacca tatctgcact aagcagaaaa atggaaccga acaaaccgct
     5821 cagaacaaag gtccagttat tttctttacg tacgactagc ttcgcagcat gaggagctag
     5881 tagtcctaca aaagataaac tacctgtcac cgctacacta ccgcttgcca aagcaacagc
     5941 taacaacaaa aggatttttt gacttttagc cacgttaagg cctaatcctt gcgcgcgttc
     6001 ttgaccaaat gatagcaata caatcctctg tgcataaagt cctcctagcg gaattaagat
     6061 aaccgcccat ggaagcaatg cccaaacata aggccagctc gcaccccaga ttgatcccgc
     6121 taaccatgca ttcacaaatc cataattttc cttagataat tggatcgtgc atagcaatgt
     6181 taatgcagaa aggccggcat taacggcaat accggacaat aagattcgat tcatacccaa
     6241 aaagccattt cgatcatagg ccgcaagata gacacagcaa gcagctaaaa caccacctag
     6301 aaaggctaca actagcaata gaaacggcag cgaatagtgc gaaaagaaac ctaaataaag
     6361 catcactaaa aatcctgctc cggcattaat gcccaatata ctagaatctg ccaattcatt
     6421 tcttgttact ccttgcaaga tataaccaga aacgccaaga caagctcctg ctaataaact
     6481 gatcagtaat cgaggaactc gaaattctct aacaatcagc gccaaagaag atgattcttt
     6541 ccctatgaac gtggcaaaaa gctgatccag gtaaataaaa ggcgtaccaa tcattaaact
     6601 acctatagac aggatgacaa gtacaaaaag caagaaatag aacgtccaat atattttttt
     6661 caccgttgtt ccctccttac ttgtatcagt aaaaacggaa cgccaatcaa tgcaatgact
     6721 aatccaaaag gtgtttcaaa agggggattg atcatcctcg ctgtaaaatc cgccaacata
     6781 accaatccac cgccaactaa aaaagagaca ggtagaacat aacgatagtc cgttccaacc
     6841 attccgcgaa caactggcgg aaccaacagc ccaataaatg aaacaggtcc gactaacgaa
     6901 acggcaatgg ctgctaacac tgcaactaga cagaaaacaa tcaaccgcgt tcgtttagga
     6961 tgacttccaa gagctaatgc atgtgtttca ctcaaatgaa tcaaagatat tgcttttcct
     7021 aatgaaaaag aaaccaaaac agcaagtata tataaaggaa acaatactgc taattgtttc
     7081 catgtgatat tggcagctcc gcctacaaac caaaaagcaa gatcctgctg cagattaaag
     7141 aattgggtaa gtgcttggct gatagcagta aaaaaagaac taatagctac gccagctaaa
     7201 atcagctgta aaggattcat gcccattttc gaaaactgca aaaaaccaaa tacgagcaaa
     7261 gttacagcaa aagaacctgc caatgacatt agaaacacag aaaaatcaga agctttaggc
     7321 caaaaagcaa aactaagggc cattgccaac gaagcacccg cgttgattcc tagtaagcct
     7381 gaatctgcta aaggatttct tgtcactcct tgcatcaatg caccgctcaa tgcaaaacaa
     7441 ctccctacaa gaaatgctcc cgccacacga ggcaaacgaa tatttcgtat gatttggtga
     7501 ctttgttttg atctatcaaa atcaaacaac gcctgccaaa aatctgcttt tcccacagtc
     7561 gctgcgccat ttgaaagagc aacaaaaaaa ataatcaaaa gaacaaaaca gaccaaaagc
     7621 aggagtctat ttttcttcat agtcctcata attgatcctc ctgctctttt ggcaacaaat
     7681 cataggttag aaaaactggt ttatttgttc ttggaagcgt gacaatcgtt gcatcaatct
     7741 caaatatttt tttcatacac tcttttgtga tcacttcttc aggtgtacct tctgtgatca
     7801 acttaccgtt tttcattgct aataaataat ctgaaaaacg tgaagcatga ttaatgtcat
     7861 gaatcgacat caagatcgtt gtttgtttca tttgattgat ttcagtcaat aactgtagga
     7921 tctctaattg gtgtgccgga tctaaaaatg ttgtcggttc atccaagatc aagatatctg
     7981 tttcctgagc aagcgccata gcgatccaga cacgctgggt ttgtccacca gacagcgttg
     8041 cgatatcccg catacgaaat ccagctagac ctgtagcatc caacgcccac tcgattgctt
     8101 catgatcttg cgtgtccatg ccactgaaca gtttttgata agggtatcgt ccgtaagata
     8161 ctacttcttc tactgtcata cctgtagggt gttcactagt ttgtgctaat aatgcaattt
     8221 tttttgcaag ttcttttgaa ctgtatgtag agatatcaga gttattgaca atgatctttc
     8281 ctgatttcac aggtagtata cgggtaaaac ttttcaataa agtagatttt ccacttccat
     8341 ttggcccaat caaactagtg attttccctt caggaatcgt aacagacatg ttttcaatga
     8401 tttttttgtt ttcgtagccg gctgcaatgt cagctgctct taatctcgtc atttcaccca
     8461 tcctttcgct gaaaatcatt ctcaattatg acgctgtttc aacatttcgt caagcgctac
     8521 tttcatatct atagccaaat gaagcggttg acagcgttcg aaatatcagg aataataacc
     8581 aatgagaaag attctcaatt atgttaggag gaaagaaatg aaattaaaaa caaaagtatt
     8641 cacattatct agcatattgc tgctggctgg agtactgagc gcttgctccc cctcttcaga
     8701 taaagaaaca gctacaactg ccaattcgac gacttcatcc aatagtactc atacagtcac
     8761 agatacactt ggacataaag tagagattcc aaacgcgccc aaacggatca tcggcagtta
     8821 cttagaagac tatctgattg cactagggga aaaacctatc gcccagtgga ctgttggcag
     8881 tggttccatt caagattatc tgcaagatga tttaaaggat gtcccaacga tttcttatga
     8941 ccttccttat gagaaagtgt taagctttga gcctgatttg ctgttgattt cttcttccgc
     9001 tactgtcgaa ggcgggaaat acgaacaata tagcaaaatc gcgccaactt atgttgtaaa
     9061 aaacggaaca gatgtcacat gggaagaaca actaaaagat gtcggcaaag ctttggcaaa
     9121 agaaaaagag gcagaaaaga tcatttccga ttatcaaaaa tccatcaaga aaactcgaga
     9181 agaactagca gataaaatcg agaacaagac agctgcagtg ttgtgggtga ccaacaactc
     9241 agcctttatg gtcagcaaaa atcggtcaag tggaagaatc gtatacgacg atctggaatt
     9301 tggtgttcct gatctagtgg aagaggtctc caaaaaagcc acttctgact ggtctgctgt
     9361 ttcctctgaa aagctagctg aattagatgc tgactacatc atccttgtga acagtgacaa
     9421 agatgctgcc atgttcaatg aaccaagctg gaagaatctt aaagcagtga cagacaatca
     9481 tgtactgcaa ttcggacctg aatctagttg gctatataac ggacctattg ccagtcagga
     9541 aatggtcaat gatatcaaag aaaaactaaa ttgattttaa ctaaaaaaag catcttcacg
     9601 attagtcgtg atatgctttt tttcttatta acaaactaga cgcatagatt ttattcttct
     9661 tttgaagcaa ccctattttt tactctttcc catttttgaa aacgatgggc atatagattt
     9721 tcttgatccg ttatcccctc atactcctct ataagggcga agtctgaaaa atcaatattc
     9781 ccaatatacg tatcgccttc aaacgtgcta tcgatcaatg ttcgccagat ccgaccagtg
     9841 taaggaagaa gttcttgaaa aatccgacta ccacccgaaa catagatatc ttctgagatc
     9901 gtttgactat acgacaaaag ttcatcgatc gaatgcatta cttccgcatt ttctttcgtg
     9961 cgaaaatttg gctgcgttgt caacacgatg atatggcgat aaggaagtga aagatccccc
    10021 attccttcat aggtctttct tcccatcact aaaattcgat ccattgtatg ttcgcgaaag
    10081 aaacgcatat catttggcaa tcgccatggt aacaaaccat ttttgccgat cagaccattt
    10141 ttatcttgtg cccacatgga aataaacata ttatccgctc cttatgattt tagatgtttt
    10201 gagataaaaa aagtctcaat tctttgacca gcaaggaatt gagaacttta aaaacattat
    10261 tttgtttcac ggtgcaaagt aactttgcgt tcgcgtgggc aatatttttg tttttccaaa
    10321 cgatcaggat tgttacgttt gtttttgctt gttagatagt tacgttcttt acaagaagta
    10381 cactctaaag tgatgtttac gcgcatgttt ttccctccca tttttacaag aatcctctaa
    10441 gatgactctc agacttgatt atcttaccat gattttttct agattgctag tgtttttcac
    10501 gattttgtta agtaaaacta cttgacgata aatacaacgg ttttacttct caaacaaaat
    10561 ctttttcttt ttgtataaat acccttacac ttgtttatat agattatgtt ttttaataaa
    10621 gggggatact aatatgccat ggaacatgaa ggactttcct gcatcaatga aaaacttaga
    10681 taaattgaca agaaaaaaag caatcgacat cgcaaatgca ttattagatg aagggtaccc
    10741 tgataaccgt gcgatcccaa ttgccattga tcaagcaaaa aaatggtatg aagatgctag
    10801 tgaatcagaa aaacgaactt tcgaaaaaga aaaaaatcca agcaagacgg atgaacacga
    10861 tacgaatcct cgtgctggaa aactgcttga ttcagatgtg atcgtagaat atgaggaaga
    10921 acaatggatc gtgaaatcta aaggggcaaa aaaggcaagc aaccattttg atacaaaaaa
    10981 agaagcaatc gaaaaaggaa agcaagtagc acaaaacaaa gaatcaactt tgttcattta
    11041 taaaaaagat gggacaaaag aaaaagaaat cgattattga acatatgtaa aggggttgtg
    11101 acgaaaatcg tgtcacaacc cccttatgtt cgaaacaatg gtgttcctct gccaactccg
    11161 aaccataagt cataatatct ataaaacggg aagagctgtt ttttgaaatt gtttcttatc
    11221 actcagtgtt aaacggtagg agaaaacctc ttttttattg atatttgatt ttcatcaaac
    11281 agtcacatag tcgattgctt ctgcttgcgg aatcgtttca tctacaaagt agactttata
    11341 ccatgtcaag aaactgaaga ttgtccagat ttttctttgc tcttctttac gtccttcgtg
    11401 atggtcatct agcaacttca tgattttttc ttgatcaaaa aattcttttg caaaatctgc
    11461 ttcgaacaat gctttgactt gttcgtagcc gtgttcttct ttcaaccaag ctttgattgg
    11521 cacagggaat cctaatttca cacgattcga ccatttttcc ggaagatgtt tgttcgcagc
    11581 ttgtctgaaa atatcttttg tgttgttttg attcaataaa aacttacttg gtatttgttg
    11641 agccaatttc atgacttcga tatccaataa aggtactcgg acttccaaag aacttgccat
    11701 agaaagttta tctgccttta acaagatatc ttttggcatc cattgatgaa gatcgacata
    11761 ttgcatctta ttgacttcat ctttgattcc ttctgttttc tcgtaatgaa cagtcatgat
    11821 ttcatccaca gatggtgctg tttgatattt tggtgttaac acttctgatg cttctgattc
    11881 ttcgaacact cgagcatgac cgataaaata ttcttttgca ggagcaagtg attcatataa
    11941 atggatccgt ccatggaaat ttttcatttt tccgatttta cgtcctaaat tatagcgtgt
    12001 tccttttggt aattttttca atccttgagc aatcacacgg atgaattttg aattcgtatg
    12061 gaatccatac gtttggtatc ccgcaaacag ttcatccgcc ccttctccag attggactac
    12121 ccgcacactt tgtgaagcaa gatttgctaa aaagtacaaa ggtacgcaag aaggatttga
    12181 atcaggttca tctaagtgat actggatcaa agggaatgct ttgaacgaca tgtctccgtc
    12241 gatcactgct gctgtattat ctaagtccaa tagttcggtt agttttctgg cttcaatcgc
    12301 ttcattatag gttttatcat caaacccgat tgagaaagaa tgatctggtt tcaatacaga
    12361 ggttacataa ctggaatcaa ccccgctgga taagaaagaa ccaacttcta catcactgac
    12421 cgtatgtgct tcaatagaag cttgaacggt ttcgtcgatt ttttcgatcc attcttgtcg
    12481 ggaatgcgtt tcttttgttt caaaatctgc atcccaatat tgctgaatgt ctatttttcc
    12541 atctttatac gtataataat ggccttcagg caaacgatag acatctttga agaatgtttc
    12601 gccgtttaat ggagaatatt ggaaagtcat ataaggtttc aacgcttctt tgttcaattc
    12661 tttgttaaaa tcaggatgag gcagaaaact tttgatttct gaaccaaaca taaatgttcc
    12721 gttcatttct gcataataat atggtttgat cccaaagtgg tctcttgcac cgaataactc
    12781 attcttttca ttatcccaaa tagcaaaagc aaacattccg cggatctttt gcaataattc
    12841 tgttccccat tcttcgtaac catgcaaaag gacttctgta tctgcatgtg tttgaaaaac
    12901 gtggccagct gcaatcaatt cttctctcaa aggctggtaa ttatagattt cgccattaaa
    12961 aataatgatc tttgtccgat cttcattgta aataggctga gtaccgccct ctaagtcaat
    13021 aatacttaat cttctgaatc ctaaagcaac atgtttatcg atatattctc ctgaactatt
    13081 aggtccacgg tgaacgattc gatccatcat tgtattaata attgtttttt tgttgtcctt
    13141 gtcgttaaca aaacctacaa taccgcacat ttaactttca catcctaata taaaattact
    13201 gtttatttca ttcatatgca tcttatcata gaataaatag cggacgaata ttttctctct
    13261 tacaatttcg tcacgtgaaa acaaaagatg aaagtttctg tttttacaga aaataaagtc
    13321 ccaatatcta atttaccatg ttttcttttt tgaggctacc ttattctctt cgtgttaaaa
    13381 aaatattagt ggatgctatt tccaaaaaaa ccagcaaaaa aagacacgac ctaaagatcg
    13441 tgtctaatta tgactgtatc agaaaatatg ataccaaacg gatctattca ttaattaatt
    13501 gacatagttt atctgttgct cttttatgac tggataactg accaattcat gacgatccaa
    13561 gtcttcttta ttcatattta cagcagtaat ttgactgtct tcatacgtac gataataata
    13621 aatcccttta tcaacgttac agcaagaaga ataaatcgta tattcgtatt ttctttctcc
    13681 agtatcgcat actccttttt gttgctcgac tgagcctagt atatgaaaaa attgactgat
    13741 actttcagat tctgaatcac ctgatgcagc attcatttta gtaaatgtgg cttttacaaa
    13801 tcgagaaaca gaagagagat ctccaggtaa gcccaatcct cccatcccac gactataaac
    13861 attcaagctg atctggtttg aaaaatgatt ttctggtgtt ccatttgata gcgagcgata
    13921 attgttcaga ttaaataatt gataatcaaa tggcggatta tttgtcaaca caccgacagg
    13981 attatcatat aaatgaagtc catctttcat actttcaatt actatcgatt tttctttatc
    14041 agctaataac cagtgtaaag gtgacaaggg tagtttttca ctaaaatcga tattgactag
    14101 attgatagta gccaataatt ctttagcttc gtctatggtt gagcattgcc ctagtatcca
    14161 tggaataaac tcaaatggtg caacgttatc ttttccttct tgtaattctt tataatcagc
    14221 attgccagga aaattcagtc ctgccatact caaccctttt tcatttgtag cctcataata
    14281 gagtggatag ttggataccc cagctgctat tcctatcatt gcataatgtt tatctaaatt
    14341 ttttaccttt ctaaaatcga aacgataatt tcttggagta atagtgacca cttcattata
    14401 agacatctca taatcaaaat tccttccaaa ataatggtct ttcgttgcat aagtgattgc
    14461 ggtacacatc gtttcccgtc ctaaaacaaa tcgtttttac acttttatct tacatctagt
    14521 atttttttta tcaaaaaaag gccaaagaag attgatttac tagcatttat aaaaaatagt
    14581 actcaggggg aatcaaaaaa tattgtaggt taaaagtaca acaataaggg gctgtgacaa
    14641 aagtcttgtc acagcccctt attccgaaca aacggtgttc aaaagcttgc atctgcggta
    14701 ataagcccaa tcaaacgaaa aaataggaaa agctattttt gtttggccgt tcttattact
    14761 tgatgcagga cagcttcttc acaacctcta atcgttgata taaggaaggt acaggatttg
    14821 aacctgcgcg ccggtattag ccggttcgcc ggatttcgag tccggtgcat taccactctg
    14881 ccaaccttcc gtaagtacta tttttaaact tttttcacga aatgtcaagc ctatttctaa
    14941 tagataaata acagaaatcg ctttttttag caaaaaagtc cattgacagt ttgcagccaa
    15001 cggacttacc gatcaaattc atactgatag aacactatct gattatttca ggattatcta
    15061 atgctaaaat cgagtcaatt gtccgtttga tcagtgcaat gatttgttct tctgttggat
    15121 gcatgatgtt tgatgacatc aatgacgcta agccagtcac tgctacccat gtaccagtat
    15181 gcagagcatc gacatattca tccgataatt gattgtatct ttcatcttct ttaactattt
    15241 cacggaaata attgtatgaa aaatcatgca ttttctttcc gtccccatgt tcatcaatgt
    15301 acaatgccat gtaaagacta tgatgctttt ttgcaaagta gatatagttc aaaccgagat
    15361 caatgatttt atcaccagta cgttcaatag ggaaaacatc ttcttttagt tgttcaaaga
    15421 tagaatccag caacgtattt tttaaatctt ccatgttttt gaattccaga taaatcggct
    15481 gtgtcgaaat ccccatcttt ttagcaatat ttctcgcagt aaatccttta aacccttcct
    15541 ttgcaacaac atcataagca gcttttagaa tttgatcctt ggtatagact tttcttctca
    15601 ttaaaactcc cccacttctt tactgcagta tatgttgttt tattgtaccc tatttttagc
    15661 attttttgca aacattttac tcaaaacgtt atattttaaa ttttttttca gtcttcttta
    15721 actttttttt gcaaaattaa aaaaatttgg ttaaattcaa tgggttccct tacattttta
    15781 gttttgacct aaatgatagt tgtccaaatc tttcatttca agttatagtt aaagaaaatg
    15841 aaaaagaagg tgtgtaatgg aaaacgaaac tgacgttatt tatattcatc ctcaaaaacg
    15901 aatcgtttca cagaaaagaa agtattttta tcttggtttt acaggtgttt ttttcttttt
    15961 attggcttgc tttctaatac tcctactgat aattggagtg gattgctaac tattcttacc
    16021 tcgccaagca atcttttgac agattatttt gctttaggcg gtttcggaag cgcattcata
    16081 aatgtaggga ttttgacctt actttctgtg cttttagctt atcggcacaa ggtgatttta
    16141 aacggtccct tatttgcttc gattctaaca gttaccggtt tctctttttt tggcaaaaac
    16201 ctttataatt ctatctcaat cattttaggt gtgtatctat acgctgtatt tgtcaataaa
    16261 cctttttctc agtacatcat gatcggactg tttggtagcg cattatcacc ggtcgttagt
    16321 tatatcactt ttggtatgcg ttttccttta ctgataggta ttttattggg gaatttagct
    16381 ggcatagcaa ttggtctact tcttccgccc ttagctgctc aaactttagt tttccatcgt
    16441 ggattcacac tttataatat tggattcacc tctgggttga ttgcgatgac ttttactgct
    16501 gttttgaggt tattcagcta ttcaatcgtc gaaaatacat tggttttcaa tgaatatcac
    16561 tttcctctca tttggattat ttttggcttt ttttcgctga cagtcggaat tggtttctat
    16621 tataattcct ttcggctttt ggggattcga gaaattttcg attcatctgg aaaattgaca
    16681 actgatttca ttgctaattc tggtattggt gctactttga tcaacatagg cttagttggt
    16741 ctgatgctgt cttcttatgt tttgctggtt ggcggtcagt taaatggacc tgtcatcggt
    16801 gctattttat ctgcggtggg tttcagtgct tttggttgtc atttaaaaaa cagttttccg
    16861 atactagtcg gaatatttat tgcttctttg tttggaactt ttcatgagat caccagtact
    16921 ggcatgcttg ttgcagctgt gtttgggaca ggtctcgcgc ccataagcgg tttttacggc
    16981 agtttttacg gtgtaatagc tggtgtacta catattgctc ttgtccataa cgtcagcact
    17041 ttgcacggag gactaaatct atataacagt ggtttttcaa ctggtttcgt tgcaggtatc
    17101 cttgtaccga tactagataa ctttaccgct gtcagaaagg aaaaaaagac acttggaaaa
    17161 agaattatca aaaagaatca tcgatgagct tcttacttat ttatattccc atgaaataac
    17221 tgaaatacgt attggagtag aatttgctga ggaagggctt ttcatagaga tacagggtac
    17281 ggcagaaact cagccagaag atttagatgt acttgctgat ttgctgaaca atcctcggga
    17341 ccctagtatg gaaatctatt atcaagaact attaggtaat ccccgacatg atcgggaaga
    17401 ttatcatctg ttaggtagtt tgattgatga cgtggaaatc atgtatgccc agccgattat
    17461 caatattaag atctttcgac gtgcttctca ttcctattat taaccctatt ttctatttat
    17521 aaaagactga atcaaaaaag cagctcctga aagttcgatt aaaatctact ttcaggagct
    17581 gttcaagctt gacattattg attttccaat ccttcataca cttcatctgt tacaggttct
    17641 aaaaactctg aattaccagc agtgatcgcc aaatgttcaa accaactgtc ttttgtcgca
    17701 ccatgccaat gtttaatccc tttgtgcgtt acgacgacat ctccagccat taatcgtctt
    17761 gctggctttc cttcttcctg ataccagcct tctcctccgg tcacaagtaa gatttgatag
    17821 ccgtctttat ggacatgcca gtgattgcga caacctggtt caaaagttac attacctaca
    17881 ccaacagaaa cttcgggatc attcactaac atattcagat agctttaccc ggtaaatact
    17941 tgagcgtaag cttcgttttt ttcacctgct ggaaaaatca cgccattgtg tatttcttcg
    18001 tgttttgtcg tcatttacgc ctctttctta tcttcgctat tttcttctaa atagatttct
    18061 tttgctaaac taaaagctga ccaagctttt ggccatccta cataaaaagc taaatgggta
    18121 atgatttctg ctatttcttc actagtaatg ccattttgct tgccaatctt cagatgagct
    18181 ggcaattgtt caaaatttcc tcctgaaatt aatgcagata tggtgatgat actacgctga
    18241 tgagcagata attcttctct ggaccatact tgtccaaata aaacatcatc attcaattct
    18301 gcaaattttg gtgcaaaatc tcctaattga tctcgtcctg cggtttgttt ttctgccatt
    18361 tctcttattc tcccttcacg actgttaggt gattcaacta tggttctaag gcaactttat
    18421 tttctattgt ttcttcgcat ttcattttaa atgtagtctt tcagcctgtc caatgcttag
    18481 tttattcagt cgatatgctt tttaagcata gttgctaacg cttttttt
//
LOCUS       DAXLPC010000052        18139 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.052, whole genome shotgun sequence.
ACCESSION   DAXLPC010000052 DAXLPC010000000
VERSION     DAXLPC010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.052"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(45..755)
                     /locus_tag="ACF3UE_001730"
     CDS             complement(45..755)
                     /locus_tag="ACF3UE_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFD3635132.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGDESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(773..1269)
                     /locus_tag="ACF3UE_001731"
                     /pseudo
     CDS             complement(773..1269)
                     /locus_tag="ACF3UE_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(1306..1758)
                     /locus_tag="ACF3UE_001732"
     CDS             complement(1306..1758)
                     /locus_tag="ACF3UE_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3635133.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWSFVKKGNKRIY"
     gene            complement(1893..2498)
                     /locus_tag="ACF3UE_001733"
     CDS             complement(1893..2498)
                     /locus_tag="ACF3UE_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFD3635134.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(2948..3568)
                     /locus_tag="ACF3UE_001734"
     CDS             complement(2948..3568)
                     /locus_tag="ACF3UE_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3635135.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(3570..4439)
                     /locus_tag="ACF3UE_001735"
     CDS             complement(3570..4439)
                     /locus_tag="ACF3UE_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFD3635136.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANKAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(4462..4869)
                     /locus_tag="ACF3UE_001736"
     CDS             complement(4462..4869)
                     /locus_tag="ACF3UE_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFD3635137.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELHENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(4888..6177)
                     /locus_tag="ACF3UE_001737"
     CDS             complement(4888..6177)
                     /locus_tag="ACF3UE_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFD3635138.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINDQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     ILLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(6204..6506)
                     /locus_tag="ACF3UE_001738"
     CDS             complement(6204..6506)
                     /locus_tag="ACF3UE_001738"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3635139.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(6531..8624)
                     /locus_tag="ACF3UE_001739"
     CDS             complement(6531..8624)
                     /locus_tag="ACF3UE_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3635140.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLEEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(9113..9841)
                     /locus_tag="ACF3UE_001740"
     CDS             complement(9113..9841)
                     /locus_tag="ACF3UE_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFD3635141.1"
                     /translation="MGLCLFALPTQGFAVAGGHGGGTSSGRSSGRGSFGGRSYGGSYF
                     GSRSYGRDSYGYYGPSTGPSSYEQTGFLALAVLSVGGVSAFSIVKNKRQKKRLKSEIL
                     SRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFAEHQKVLQKNKAD
                     GVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLISGSKTQRQYFSQ
                     IWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(9986..10699)
                     /locus_tag="ACF3UE_001741"
                     /pseudo
     CDS             complement(9986..10699)
                     /locus_tag="ACF3UE_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
     gene            complement(10700..12607)
                     /locus_tag="ACF3UE_001742"
                     /pseudo
     CDS             complement(10700..12607)
                     /locus_tag="ACF3UE_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
     gene            complement(12721..14053)
                     /locus_tag="ACF3UE_001743"
                     /pseudo
     CDS             complement(12721..14053)
                     /locus_tag="ACF3UE_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(14019..15497)
                     /locus_tag="ACF3UE_001744"
     CDS             complement(14019..15497)
                     /locus_tag="ACF3UE_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3635142.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(15802..17637)
                     /gene="tdc"
                     /locus_tag="ACF3UE_001745"
     CDS             complement(15802..17637)
                     /gene="tdc"
                     /locus_tag="ACF3UE_001745"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFD3635143.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEQVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     EQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
     gene            17864..>18139
                     /locus_tag="ACF3UE_001746"
     CDS             17864..>18139
                     /locus_tag="ACF3UE_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635144.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDV"
BASE COUNT         5204 a         3871 c         3083 g         5981 t
ORIGIN      
        1 aaaaaaaaac ggcaatgaat gccgctcttc ttatttcgat tcttttataa ttctgcttct
       61 gattcatctt tggttagtgt gtgtctaaca ctagttacgc caaatgtttg atcgattttt
      121 tccttcaacg cttcgattgc ctgtgcgcca cgtgccgctt gttcagcatt gatggattca
      181 atgaccagca ccgctgcttg tgtttcttcc gtcagcatcg ttctttgggc ttcacgccag
      241 ttgagacagc gacagatcgc tccttgttca tcatagtaga tgatttcttc cggaagtgcc
      301 ggagcatcgg aatctgcacc taaaggcagg aatgattcgt caccttgggc ttttcctaaa
      361 tgcagatttc ctgcgatctt ttcgatatct tctccgccgc aaggtacgcc aaaagacaag
      421 gaaatactat tatagatatc tacaagcgga ttgattggga aaaattcccg ttcttgattt
      481 gcacgtttca gtaaagcttc aatagaagaa cgtgcacctt ttttagtctt gaatgtggta
      541 aatgcctgac gccactgagc aatgacttcg ttttggctga atgtttcttc tgtaaggtaa
      601 tttcttgctt cttttgctgc ctcattcaat aattgatgat acgtttcttc actttctttt
      661 gttacgtggt tatcgatacc atttacggat aagatttcga tggttgcttc aggaaatact
      721 tcccagaaat tggtatccac tattactttt ttcatctgtt cacacctctt gattagaata
      781 attgcttgat gaatagatag tctgtttggg gatcatctcc catataaaaa acatgttcgc
      841 tgtatttgat aaatcctttt ttacgataaa aagcgagcgc aacatcgttg tgttcccaaa
      901 caccgagcca aatggctgtt ttttgctttt cttttgcttt ttcaatagct gtatctagta
      961 aaaatgtacc gataccttga tgtttaaatt tttttcgtac atagattcgc tcgatttcta
     1021 aaaaatgatc agccatttcc tcagattgac tcgttcctgt atttagtttc aggtaacccg
     1081 caggctcttg atcgatactc actaggaaaa aatctgtttc tttatctttt agctcttctg
     1141 taagtttttc tagtgcataa gcttgtgtca agtaatcagc taaatgctcc ggtaattatc
     1201 ttttccaaat gtatctgtaa atgtttcgat actaatttgt tgtagtaagt ctacatctga
     1261 aggcgtcatt tttcgaattt cgtatttatt cacggcttct tcctttcaat agatcctttt
     1321 attgcctttt ttgacaaaac tccaatcttc gctaacattc ttgcatactt tatttaaaag
     1381 atattccaat tgttttgctt cttcgtcaga aagaccattt aatgcgactg cattggagta
     1441 gttgttttct cgaatgatga aaggatagat ttctgctcct tttttagtcg gatagagttt
     1501 cttgattttt ttattttctt tatcttccaa acgttcgatc atcccattgg attctaattt
     1561 cttgattgct cgggcagtcg ttgtacgatc tactttgatc atttctgcta gtttttcttg
     1621 gatgattcca ggattttcgc aaatacgtac taaataaaga tactgtcctc ttgttaaatc
     1681 gacttctttg aattcgatat tgctaataga gtctagcgct cgggcaatca ttccgatgtc
     1741 tcgaaggatt tcagccattt catcccacct ttattttgtt tgtaagacta gtttacctct
     1801 ttttgttgca aatgcaacta tttttaataa aaaaatcaag ttctttttta ataactagta
     1861 aagtatattc ttttcttctt ttacgaaaaa gctcaatcac aatagatctg gtttttgttt
     1921 tctaaaataa gtaactgttt cttcgttgtt cgcttttctg atagctttgg caactcttct
     1981 atactaaaaa atcccatgtt ggaagtttca ttattctcaa taaacttggc ctcttcaccg
     2041 tggatcgcac aagcaaaaac aagtttataa tactgaaaaa gctgtggaat atctttttgt
     2101 ttattcgtat caaaaactgc tcgcaactga gtagtttcta ctgttaatcc tgtttcttca
     2161 tagacttctt tacgcacatt ttcttcagga gacaatccta tttcagcaaa tccaccagga
     2221 agtgaccatt ctttcgtccg tttatcttcg attagtagga ccttgccatc ttttttgata
     2281 taggcacgaa catctacttt tggtgttgga tgtccttctc caatcgttgt gagcgctttt
     2341 atttcttcga aagtttcttt tcctatttca ctgatcagtt ccaatgaaat cgtccggatc
     2401 tcctcaaaac gctctttatc aaatacatct tttccataat atagaccagc ttgagaaagt
     2461 gcgagtagtc ttttgtattg agccaacttc ttgttcattc tcttcccttc ttttttagca
     2521 aatgtatgac tatgtaatca agtatagaag actggtttaa ttacggcaaa taaatataat
     2581 gaaatctgca ataaataaaa gaatgttaaa aaactcgaga acaaaagaca ttcgacttct
     2641 ctggggctgt gaataaatgg cgttcaaaag cttgcatctg cggtaataag ccccatcaaa
     2701 cgaaaaatat gacgagctat tcttgtctgg ctgttcttat taattgaggc aggacagctt
     2761 tttcacaacc tccccactaa acggtgttct cctaccaact cctcggtcac aagtcacaat
     2821 attcatcaaa catgagaagc tgtttctttg aaattgctcc ttgtgactcg gagctgaacg
     2881 acaggctcac gacctctcgg taaacggtgt tcaaaagcca atttttcgat attaagccat
     2941 ttctttgtta cttattgtca ttgatttctt tttctaattt atccaatagt ggagtgtaat
     3001 ccacttgagt atagtctgtt acatcaaatt catatagtgt tcctaactgg aatttgtcat
     3061 attttcggtc ggcgatgatc tttttgaatg cttctttcgt aatatgattg gtccctttcg
     3121 ttcgatcttc caatacgtca ccatagtgat aatgatccat gatatagctc aaatgacgat
     3181 ctgattcacg atcacgtttg taccgacgtt gccataacac ttcaaagtct gctgttaggc
     3241 gaatcgtgat cacctgatat ccgtatctat ctgctaattc ttggagtcgt gctttttgct
     3301 tatcactaaa aggatactcg gacacaatca ctttctttcc tgcttccata tacaaatcaa
     3361 gtgctttgta atagaaagga taaactttcg tcctttcttg ttccgcccgt tcttccaaat
     3421 tgttaaaccc gatggattct gcatagtatt ccttgatttc atcgagcgtg atggcataca
     3481 tatctggaaa tcgttcccgt agtttattca taagatatgt ttttcctgta ccaggactac
     3541 cagccagaag aatgaaatac tttttcatct catttatttc ctaagttaat tggactttcc
     3601 aagttcataa acagtccaat cttatgcttg acaatttctt ttactgcttt atttgctgga
     3661 atcacattat ggcgaagaga cttgttgatt tctgtttcac taaaggtttc tttagctact
     3721 ttcgtccagt tgactaaaag ctccgttcca acattgaatt tgcggatccc gttattgatc
     3781 aattcaggat aatcttcttc tttcacacct gttcctccat ggataactag ggggacatca
     3841 actactgcat cgatttcttt cagcaaggga atgtttactt ctgtttttga tttgaattgt
     3901 ccatgattcg taccgatagc aatagctaat gcatccacgc ctgtagcttc tacaaatttc
     3961 actgcgtctt ccggtcttgt atataccttg tcattttcag cgacatggat tccttcttct
     4021 gtaccgccga ttgttccaag ttctccttct acggaaacac cgtgcgcatg ggcatattct
     4081 actactgctt ttgtcttcaa gatattttct ttgaaaggta gatgggaccc gtcatacatg
     4141 acagaagtat atccgctatc gattgcttct ttgatatcat caaagtctcg ggcgtggtct
     4201 aagtgtaaga ctgcatcaac catttcttct tctgcaatag ctgtcattac attgactaac
     4261 acatgcatgc cgatatattt agcggtatcg acacttgttt gaataatgat tggcgaaccc
     4321 atttcttttg ctgcgcctag catggcagga agcatttcta ggttatgcgt attaaaagct
     4381 ccaactgtaa aattcaactc ttctgctgtt tttgttactt ctttcaatgt tgtatacatc
     4441 ttttattgcc accttatctt tttatttgtt tcctttgatc gttacttgtt ttgcaatttg
     4501 tcgcatctca tccattttgc ccatgtagta atcgatccct tgatcatcac cagcacgagc
     4561 agcatctgca cgcttctggt tatagaggct catcagtttt ttatacccat ctccgatcgt
     4621 ctgtttattt tccaagctct tttctaaata ttggatggct tgatcgttct catgcaattc
     4681 agaaaattta agtccaactt gttcataaag ttccgctaat ttatgcctat cttgggtagt
     4741 ggaaatctct tgtttcaatt gtgtaatctc tgattgaatc ttttcggtcg cttctggcga
     4801 tagggctttt tcttcttttg ccagaacttt tttcggttct ttttcttttt tcttaaaaaa
     4861 tccaaacatc attttcccta ctttcaatta aaacgctttc aaaactgggc ttaagatcca
     4921 ggcatataag agtgctgcgg ctactgtatc tacatcggtt gctgtagcat tgatgaatcc
     4981 catcgaatta aagatcgtta ctagcaaagc gggcaataat gtaataaaga aaccatgagc
     5041 aataccgcca atgatcgctc ctcggcgtcc gccaactgcg ttgccaaata tccctgctgt
     5101 ccctccggca aagaaattgg ttagcatacc aggtaaaatc atcgctaagc cgaacatggg
     5161 caaagtaaac atggcaataa tcgtaccaat cgttgtcgta atgaaaccta aaatgacggc
     5221 atttgggcta taaggaaaga aaactggaca atctaaggca gggatcgcat caggaactaa
     5281 tttcatagct atccctcgaa atgccggcac gatttcacct aacagtagac gtacaccagc
     5341 tagcaatata tacacaccca ctacgaattg gatggcttgt aaaaaggcaa acatgatata
     5401 gttttgatct cctgataatt cagaagcgaa tggttcgcct gcaaataaaa cagtgatgat
     5461 atatagcggg accatcacga ccatgacaga caaataagta tcttgcagaa attcgaaatg
     5521 tgtcggcaac ttgatatctt cgatcgactt tttattttcg cctttctcac caaaaagctt
     5581 agcaacaccg gcttcaaata agtacccgat cgtacaaaaa tgacctaaag caatatcatt
     5641 tgatccagtg attttacgaa tgatcggttg cgctactgcc ggcatagcaa tggcgaaaca
     5701 agctccgata aaaccaccga ccaagatcaa tacgatccct cgcagaccgg caaaatagcc
     5761 aaagactgtc gtcatcgttg ccatccataa aattgcttga ccagttaaaa aaatgtactt
     5821 ccattttgtg aaacgagcca aaataatatt gaatacaaaa atggctaaga acgtcagtgc
     5881 aatatctcta cctaaaccca aatcattcat tgcttgatca ttgatagatt caatagaagg
     5941 gatgatccct tgcatatgaa atccttcagt aaagattttc ccgaaataag ttaaacttcc
     6001 aacgatgatg ctcgaaccgg cactcaatac ttgaaatcct aggagtgttt ttaacgtgcc
     6061 agagatgact tgtcctgctg atttcttctg cagtagtaga cccaacatag caatcaatgc
     6121 aatggtgatc gatgcctgag tcaaaatatt ttcgatgata aaattgataa cgctcatgtt
     6181 tttaccctct tttctttttg tatttagata actcccttat cttgcagaac tggggtgatt
     6241 ttttcttcaa tttcattttt tgaaacaata tttttcaaat agatcatcgc cgttttagga
     6301 tcaactgcga acttttcgaa ctgcgaacga aaattttctg ctgtgatgat cacatctggt
     6361 ttcatggaaa ctgcggaaga aatatcacaa tggtccagtt tggcttctac tcctaatttg
     6421 ttcaaaacat cctcagcaga catctgtgct gcaaaactac ttcctaaacc tgcgccgcat
     6481 acgaataaaa tgttcaattt gttcatcttt gttctccccc gtatcattta ttatttctca
     6541 actactgaaa aaagcagttg tttgaaatct tcgatatttg tgcattcaat caatcgatcc
     6601 aacttctctt cgttgttgat caattcaatt agttctttca tgatgttcag atgggagtag
     6661 gagtctactg ctgccaaaca aaaaataatc tttactggat ccatttcagg attaccgaaa
     6721 tcgattggtt gctcaatcgt agctacgctg actcctaatt tattgacccc atcttctggt
     6781 cgggcatggg ctagtgccat gtgtttgcca atcacgatat acggtccgta atcattcact
     6841 gcacgaatca tcgcttcgac atagcgctct tcgacaatgt tttctttaac caatggtcta
     6901 gcagctagtt caatcgattc ctcccaagta gtggcttttt ctttgatcat gatattgctg
     6961 tccgtcaaaa tatcttttaa cataggctgg atctcccttt tgttgatttc taaattgttt
     7021 gtttcgaata atttttctaa cttgccatag atgattcgat ctactcggcc accactttct
     7081 ttcatgacat ctattatttg agtgaataac tccgtcgatt catgactgtt aggctctaac
     7141 cgctgtagtt cttcatttct tttcaaaaag tcttctataa ccaagatatt cgtctcagtt
     7201 aaaatcggat cgacaactaa aagcggctta tttcgataat tcaattgaaa ggtgctgaaa
     7261 accagattga catccaattt atctactaat tcgatttctt ttgaacttaa aactgcagta
     7321 atctcgatct gaggaaactt ttctttcaga ttctctgcta acagatttcc agtagccatc
     7381 ccatggttac agacaacgac tgatttataa acataattca agtctcgctt gattacactg
     7441 gcgatcgtcg aaaagtggat gacaagaaaa gctatctcgt cctccagtat cttgccacca
     7501 attacttctt cgatcgtagg aacaaaatga gtgactgcgc ggtagattgg gaaataattt
     7561 gttcggatgt tttctttcaa tggattcatg acttggatat gattcttgat tcttacaatc
     7621 agtgcagcca tgtgcttata gagattttcg aataaggctt cttcctttag atggaaaggt
     7681 acgtgtgtct cgttctctac aaattggatc aattggatcg ttagtaattg agcttgtacc
     7741 cactcgattg aattggagat atctctagca ttgaacgtct caatagtgaa acgaagataa
     7801 tttctttcta cttgcgggac attgtccaat tgaaattcct cgatcatgtg gtcaataaat
     7861 gcagaaaagc tactgtcttt tatttctgta tttttccaat taatggcaga gataaattca
     7921 tgtttcctga ttcgctggat ccagatcaat gtaaaaagca ggatttgttt tttataaata
     7981 tcatcttctt gtttcaacaa cttattggaa tagatctcct gtattttttt gatttcctcc
     8041 aaaggaaaat aatggagaaa gattttttga gccggtgtta attgtgcatc ttgattcata
     8101 aagaagtcgg tcattcccag attctgattg ataaaatcat agatcatcgt acggatagat
     8161 cgttctgaac ctttataaac cagtccttgc tttccataac tgacgatctc tatcccataa
     8221 ctgaccagtg ttgctcgtaa ccgtctcata tcttcatcta atgtactttt agagatttga
     8281 aattcttctt cttttttgtt tagatggatc gggattcggc tgtaagcaac ggctaaaact
     8341 agatcaaaaa tacgttcgcg ccgattcaaa aagccgtctt tcacatcttt tatttcagtt
     8401 tctaatcgag cttgcttttc cttttccagc ttcaacaaaa aacctttgtt gcgaattgta
     8461 cggatctccg gaagcttttt actgctcaac cagatattcg cttcaagaac ttcctgacga
     8521 atcgtccgct gactgacatt gaactcactt gctagatgtt ttgcttttac tggatattgg
     8581 gctgtcatga ttctgtgaag tatttcaatt gttcttgttt tcatagaaat gatctccttc
     8641 tgatttcaag tatatggttc cgcttacata ataaaaagta gatatttctg ccacttgaag
     8701 tggaaagaaa gtaagcaaag caaacaaaaa ataagccata tgctttttca tctcctcaac
     8761 gaaaaagaca tacgcctatt attacaaaaa ttttgcccat ctatacaaaa aagaggttgt
     8821 gaaaaagctg tcctgcatca agtaataaga acaactaaac taaaatagtg cttcctattt
     8881 tttgtttggt tgttcttatt atcgcagatg caagctttta aacaccattt agtggagaag
     8941 ctgtgacaga gatgttcagc cttgagcgat aagaagcgat tttgaaaaat cgcttcccat
     9001 attttacaaa atcgtgcctt attgccgata ggctatctct ggaacaccgt ttattcagaa
     9061 aaaggagctg cgacaaggct tttgtcacaa ctccgttcat aaatatttcc tgtcaatcca
     9121 gcataatcgg ttgaataaaa tcggcttgcc atcttttttc tttctcagaa aaatcaaaat
     9181 accatatctg agaaaaatac tgtcgttgtg tcttacttcc tgagatcaat cgcccatctt
     9241 ttcgatcgac tgaataatca cagcatctga aatcaattcg gatggcaaaa ctattttcgt
     9301 ggatctgtcg ataatttcct acttcctgaa tagttatttt tttagtatga tttcttacac
     9361 cgtctgcttt gtttttttgc agaactttct gatgttcggc aaacagcttg tctgtataac
     9421 agcttctggc tttttcagga gtttcttctt cccaagcgga ttggatcttc atgaatatct
     9481 tttggatttc caaaaactgt gctttctttt ctttagccgt tcctgacatg cgggacaata
     9541 tctccgattt cagccttttc ttttgtcttt tattcttgac gatagaaaaa gcagaaaccc
     9601 ctcctactga caaaacagct aatgcaagaa accccgtttg ctcataacta gaaggacctg
     9661 tacttggacc ataataccca taagaatctc tgccgtaaga acgactgcca aaataactgc
     9721 ccccatatga acgaccgcca aatgaacctc tgcccgaact tcgaccgcta gatgtacctc
     9781 caccatgacc acccgcgaca gcgaatcctt gggtcggcag agcaaacaaa cataggccca
     9841 ctaacaaaat gattgctaaa taattgattt tttcattgtc ttcctcgtta tcttttatta
     9901 caaaaaacta ttttatcata gccttgctaa aaggaagagt caataaccag atgcataaac
     9961 tgttttttta gcaattttgt cttatttagt cattgagtaa catcggacag atgtatgtgt
    10021 cggcagtcca taattcctct atcttcagca tgaacaagct tgcagacaag agatctgcgc
    10081 ttcctccagg agagatttgg ttttcctgac aaaagtgcaa cagtgctgta aatggacgat
    10141 ttggtaaagc actttgacta gcagcatgag caagtttttg catttccact aacgttttct
    10201 gatcactgcg atgcaatacg catgtgtcat ctagcgaact catcaaaact aacaacatat
    10261 gcatttgttt ctgtacatat gaatcattat ctagctcctt agctgcttgg attgcaagcc
    10321 tgatatgcgg ataccctaat atcgcttctt catatgcacc atttacgcca tatttttgct
    10381 tcaccctatg accatgagtg gtttttttat gacgatattt tgtatcagga aaagcagcaa
    10441 gcttgctgac atcatcaagt attttcgata aagaaaaagg ctgttccata ctgatttttt
    10501 gtgcaatgac actgatcaat agccccattg cccaaatcgc tcctttatgg gtattgatgc
    10561 catttgtagc aatcagcatt gccttttccg cttttcgccc aatctcagca attctttctc
    10621 ttaactcctg atcaatagca taatgccatg ctatttgagc catttcttca aaaaaaggag
    10681 ttagcgtctt agcagactta tccaaaatgc gccgaccttc ttttacggct tttgcgatcg
    10741 tatggaaatt atcatctcct aaaaccatat cagctgcctg tttgcttact tcactacctt
    10801 tgattcccat agcgattcct atatcggctc ttttcaaagc aggtgcatca tttacgccgt
    10861 ctccggtcat tccgacgatt tctccatttt tctgcaaagc tttcacgatt cgcagtttgt
    10921 gttctggtgt cgttcgagca aagacgtcga cttttggtac ttgtcgaatc aactcttctt
    10981 cagacataag atccaaatcg atcccttcta aaactttagc agtatgtttt aagccaattt
    11041 gttccgcgat cgcttttgct gtatctttgt gatcccccgt aatcattttc actgagattc
    11101 ctgcttgttg gcattccttt acagctttga ctgcactttc ttttggcgga tcaatcaacc
    11161 cagcaatccc tgcaaaagtt aattgggtta aagactcatg cgtgagttcc tgtttcgaat
    11221 ctactttttt gtaagcaaat cctaaaacac gctgaccttt tttcgcaaac gctgtggctg
    11281 tttgacccca tgcttcttat tctgaagaag aaagagttga tttagccaat aatacttctg
    11341 gcgcaccttt gacgtaaatc acccctcctt tttcctccgc atgcatcgtt gccatatatt
    11401 tgtattcaga gctgaacgga atttttgctt ctattttttt caaaggcaga tcggctgttt
    11461 cggtgtggcg aatcagtgca agttctgtcg gattgccact taaattttct gttttctgtt
    11521 cttctttcgt ctttaattcc tgacaatttt tcataataaa cagtacgcga gtttcttcct
    11581 ttgctgctac atccacaact gtcatttcat tttttgtcaa tgtccctgtc ttatctgaac
    11641 agatcactgt catagaacct aatgtttcta cagaaggcag tcctttgatg atcgcctttt
    11701 cttttgccat ttcatgtact ccgacagata ggatcatggt caacacagct ggcaatcctt
    11761 cgggtaccat tgacaccacc aaagcgatca tagctgaaag aaggatatgc caatccatgc
    11821 catagcggaa tgttgtaaaa acaactaaga acaagatcaa acaaagaatg ccttgaaaaa
    11881 tttgtttgtt caatcggttg atcttcttga tcagaggcgt cgtttgttgt tcgaccgatt
    11941 gcagtgcttg attgatttta ccgatttctg tcgtgtttcc tgtttctaca acgacaccga
    12001 ctgcagaacc agattgtaca agcgttcctg aaaaagccat atttttttgg tcaccgattg
    12061 attcttctgc tgccaaaacg gaatgatttt tttcagatgc ttctgattct cccgtcaaaa
    12121 tcgattcttc tactagtaga tcatgtactt cgatcaaccg aacatctgct ggaacgacgt
    12181 ctccggcacg taagacaatg acatctcctt ttactagttc tttcgcaggg attttttctt
    12241 gcatcccgtt cgatagtact atcgcttctt gtcccatcag ctgcttcaaa ccattcaacg
    12301 attcttctgc ttttctttct tgccaataac taacgagtcc gttgacgatc actacgaata
    12361 aaataatact tccttcgatg tattcgctcg aagcaaattt caaaaaagag gcaatgatca
    12421 acacgatcat cagcagatca gtaaagtgtt ttgctatttt tttccatcgt tttgtctgct
    12481 gtcttgcttc tatctcatta tatccttgat cagtcaggcg tttctgccgt tcttcttgcg
    12541 acaagccttc tgttgatgtt tgatagtttt tcaatacatc ttctaccgtc aatctgtacc
    12601 agttcatcct atcccctcct gtttaattga tactgttatt atacgcaggg aagttttttc
    12661 aggcgtatcg attatttcag gggggtctga aataattcgt tttgcagaat gtatctgggc
    12721 ctaactgata tttctattgc ttattctttt atatacaaaa tttaagaata caaaccagat
    12781 aaccaataaa aaaggaataa agcgtgtcgt gctttcgaat aacaagctga aagcaattga
    12841 agtaaaaaac accaacaaag caagatcttt atatctttgt gtagtgttcc gtttcttttc
    12901 tttaataaat tgaacatgtg cacacaagat cgaagaccac acaaatagaa aacaactcgt
    12961 tgtcatgcct gccaaaagct gaaaaaacaa tcgactatca gctacaaaaa aaatgtagac
    13021 aaagaccgac aaaaaataac atccctgtaa ttaaaatacc gtgtaaaggt acgcctttct
    13081 tagaaagcgc acaaaaccaa tggggcaaac ttttctcttt tgctgtttga tataaaatcc
    13141 tgctagtact gtagactgca ctatttgctg aggacaaaga agcaaccaaa atcattagat
    13201 tgacaattgc tgctccgctt tggcaatgga tcacttgcag catagtcact aaaggacttt
    13261 cttttaaatc taaacaatgc catggaacaa caaataaaat cgacaaaatc gttcctatat
    13321 agaaaaagag gatacgccaa ggcagacagt tgattgcatt tttcaaattc ttttgtgggt
    13381 cactcgtctc accaactgtt aatccgatca tttcaattcc agcaaaactg aataaaacca
    13441 taggaaatga agcaatcatt ccagcaaagc caaacgggac taattcattg agctgtccaa
    13501 aatttgcttt gattccaata gactgggtat gaaaatctga gacactcaat cctataccca
    13561 ataagataaa aaggaaaatc cccaagatct tgatgattga gaaaaaagat tccaattcac
    13621 caaaccactt gactgcaaca aggttgactg ccattaagat cattagtgcg ctacctccgc
    13681 ttatcaaagc tggtacatgt acaaaccaga aatggatata caatcctatt gctgttaatt
    13741 ccgcaagtcc agctccaagc cagcaaagcc aataagtcca attgacaaaa aatgcccact
    13801 ttttgcctaa ataatagtca acgaaatcac tgatagagtt aaatgtacta tttgctaaaa
    13861 ataaatcacc catgacccgc atcaaaccat aaatagccaa accgcatatc aaataaacga
    13921 gaataacagc tggccctgct gatgcaattg cctttgctga acctaaaaat aatcctgttc
    13981 caattgcgcc acctaatgcg attaactgga tatttcgatt agttagagtc cgtttcattg
    14041 ccggtttttc catcaagttc acctttttct ttttcaagca gcatggcgac ttcctgttcc
    14101 caagaaggtt tctttatttt ttcaatacag agtggtacta caaacaaaat gacactgatg
    14161 gctgtgactg caattagatt gatccatgtc ccagctttca tcgtcagtcc gacagaaaat
    14221 ccgattgccg caaataaaac aataacgaca gtccaaactc caagattgct ctttttctct
    14281 ttttttccaa ttctaaatgg tcgattcaac tttgcatgtg tataacgcaa tctcaaaact
    14341 gcgatcccca tgatgacata gacgatacag tagataacag tagttgaatt tacgagcatc
    14401 aaaaatgctt gattgacgcc aggaatcagc aaataaaaaa gtgcaaagat tgagataatg
    14461 acagactgag tcaaaataac ggatttggat acgtcaaatt gattcgtctt ccaaaaattg
    14521 aattttggtg gatacgcacc ttttctagca ctttctgtca ctgtctttgc tggtcctgag
    14581 gcccaagcag ataattggac tgctacacca atgaagacaa gtaaactaaa cagattcaca
    14641 ataagatgtg gcaaaccaag aatttggcaa taaatcgaaa tagattgcgc gatattattc
    14701 aattccattt gtccttttgg tacgacattt gctacaacta aagcattcaa aatattgacg
    14761 aaaaatataa aaattaacgc ggcaaatact ccgcgaatat acgttttaac tggatttttc
    14821 aaccgagtga tatacacaga ggacatttcg ataccagtaa aaataaacat gatcggcgca
    14881 aaataaacaa atgaggatgc agtcgtagta tctggtatta atttgtccca tgaaaaactg
    14941 cctaatgttc cggttggtac gatcccaact ttgatccacg cagcaaaccc taataagagc
    15001 atcatcgtca aaggcacgta caatcctaac caaacaccga cttttccgcc gatttttgcc
    15061 atatcaaatt tcaaattcaa aaaagtgatg atccaataaa cgactaaaat gacaactaat
    15121 gtaaatttgc tgttcaaacc aagcggcaca ttatcgataa tattaccaaa caacggagca
    15181 agtgctgaag cgaccatcac catcccagga aacatttgga cccataacag ccatgagaca
    15241 acgaaccccc atttttttcc tagagcattc gatacccaaa gttctggacc acctttttgg
    15301 ggaaacattc cggcaaattc accagagatc aatgagattg gaaaagcgta caataatact
    15361 gcaaccagca tgtaaaaaat catcgtccag ctcgttgctg ctacatctgg aatatttcgt
    15421 acacttgcta caagggcgca ggtcattccg ataaaggtca tggtcgtgat ttgctttgat
    15481 gaaccagtat ctttcatctt tattccttct ttcaatagcg acatatgttt ttgttttctt
    15541 ttatttttgt tcaagaacag aaatgacaag gtttcatcga ttcagtacaa aacccagtat
    15601 caccgaaaca tccattgaac gatcttagtg aactgggttt gatacatgaa acgaacgatc
    15661 caacttatag aacgttttat aaaaaagaat atcttggcga ggaatatatg aaaaacaggg
    15721 ggaaatacaa ttgttttgat gaagcaaata attgtctgtt ctccatatgt ctcttgttat
    15781 tctttcacac aaaaatcagt tctattggat gatttcgttt agtttctttt ccattgcttt
    15841 ggcgatttct tttgtataaa aattgaaaat tcgatcatca ttcaaataag gagtcatgat
    15901 agccgcacgt agcagagtga ttttctgttc ttttttccat tcttctttcg ttagacccat
    15961 tctttcaaca aaacgaatcg gagaatcacc gtaatcttct tgtgtaaatg tagtatgaga
    16021 agtaataaac cgttcaccat aaacatcgcc atccatataa gaagaccgat cgaacatttt
    16081 ttcatttaat tcattgatag cgttcaaatc tgtacagcct tgttctttga atacccaatt
    16141 gaccatatta aaatcaggat gattcaatgg atagacttcg attgtttttc ctttaacagt
    16201 aaaagtcaga tgatcgagaa attctctgaa tctttgagct gcctcgattg aagccccaat
    16261 caattgacca tatccggtca cattcaatgg caatacacga tgtgctgtcc agactgcggc
    16321 ggcggttgct ccagcttttg atccttccaa aatataagct cctaacatat ctggagcctt
    16381 tactgatttt tcaaacacat atggcgcgaa ataagaaatg atatttctca tatttttatg
    16441 tttgattacg attcctccag cagcataagg gacatagccc atcttatgag gatctatcgt
    16501 gacagaatcc gcttctgaaa tagctctgaa cccttcatat acctctttgt caatcgttac
    16561 gcagtggtgg aaaacatgat gttcttcaaa gaattcagct aaggaagcat acggcacaaa
    16621 ttctcctgct tcgtttagaa acagtgaacg cgcatagccg ccatatgcgg catcaacatg
    16681 taaatagaaa tagatccctt catcttttaa cctttctctt aattggacga ttttatctac
    16741 actgtctact tgaccttctt ctgtcgttcc tacgacagca accacaccta gaattgggat
    16801 tttttgttca gctaattcac gaattgtttt ttccaaagca ttaatatcca ttcgataatc
    16861 ctcttgaact gggatagcaa ccatctgatc taagcctact ccgcaaatat ctaacgcctt
    16921 catccaagaa tagtgttttg tttgaggcac cagccatttc cctaatcttt ggatattttt
    16981 tccgctacgg gaagaagctg ctttgacctc atccatttct tcgtccgtaa agctttcggt
    17041 catttccaaa atttcttcaa cagataaatt caaaagttcc cactcagaca tttttttcac
    17101 ttgttcaggc agcacttcct tgacagctaa aggaatcgat ttgatgcagc gggcgtacca
    17161 taatccttca agattagcaa tagaaccatc tgctgcaatg tgtccccatc cgtctgtcat
    17221 attgaataat gaagcaaaat cctgtcctac ttctgcttcc atttgcgaag ttgccataga
    17281 agattccaat gcaacattat ttgggttcca cagcatcgca tagttgtaag ctaataaagc
    17341 aggcatcaat gtttcagcat tcatttgtcc ccagtaacgg cctgctgaat gccatgggat
    17401 cgatcctgcg cgtaatcgct gactgacttc atccaagacc tctatcatat ggtcgcgggt
    17461 ggctagataa tctggagtga gcttatctcc ttcgctaatt gcaggcatat ctgaaggaat
    17521 ataattttct ctccatccaa gatgttcatc taccatcttg ttcaacaaca ttttataaac
    17581 tggtccattt tcagctttgt cgcctataaa gacggccttg atatccatat ctttcatttt
    17641 tcttccctcc atattttgtt ggtcaatgtc tcgcagatac atgtgtttat ctgtaacacc
    17701 tcttcactat agcgccaaaa atgagaaatt tttttttata acatcaaatc cacgtagatt
    17761 tttacaacgc gaattgtaaa attaagttag aaaaataaaa aggcatttat ggtacactca
    17821 aattgtattt ccgacgaaag aaaacaaagg agtgtaacca taaatgacct acaaacatct
    17881 taccatagac gaactgacaa tgatagaatc atattatctt caacataata agccggttga
    17941 aatcgctaac cgaatgggac gtgctataca aactatttat aatgtagtca ataagttcaa
    18001 gcaaggcaag actgctcttg attattggca ccagtataaa gaaaataaga aaaaatgtgg
    18061 tagaaaagtc attcaattac ctgctcatga agtagattac attaaagaga aagtcactct
    18121 tggttggacg cctgacgtc
//
LOCUS       DAXLPC010000053        18106 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.053, whole genome shotgun sequence.
ACCESSION   DAXLPC010000053 DAXLPC010000000
VERSION     DAXLPC010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.053"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..241
                     /locus_tag="ACF3UE_001747"
     CDS             <1..241
                     /locus_tag="ACF3UE_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635145.1"
                     /translation="PKKRKKKTVSDIELQIKELQKKKEELILKSKADIGDFVLSTLSK
                     LDISIESIEENKELFYDELETLLNANSQNFSELLK"
     gene            244..501
                     /locus_tag="ACF3UE_001748"
     CDS             244..501
                     /locus_tag="ACF3UE_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635146.1"
                     /translation="MANNDLNDINKRIEKLKIQKNILRANSEQNINRKRRTKRLIEKG
                     ALLEKYFEIDYLTVEETEEFLKIFSEYIKANKPKKYQKKEK"
     gene            complement(524..757)
                     /locus_tag="ACF3UE_001749"
     CDS             complement(524..757)
                     /locus_tag="ACF3UE_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635147.1"
                     /translation="MRGINNHQKYDFDLYQIEARSPMSTREITLTVDFIEKKVSGDII
                     AFGDWYDLDIESVNEILKQLKKEGQTLRTINFI"
     gene            1027..1419
                     /gene="merR"
                     /locus_tag="ACF3UE_001750"
     CDS             1027..1419
                     /gene="merR"
                     /locus_tag="ACF3UE_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="HFD3635148.1"
                     /translation="MIYRISEFADKCGVNKETIRYYERKNLLQEPHRTEAGYRIYSYD
                     DVKRVGFIKRIQELSFSLSEIYKLLGVVDKDEVRCQDMFEFVSKKQKEVQKQIEDLKR
                     IETMLDDLKQRCPDEKQLHSCPIIETLT"
     gene            1444..3084
                     /gene="merA"
                     /locus_tag="ACF3UE_001751"
     CDS             1444..3084
                     /gene="merA"
                     /locus_tag="ACF3UE_001751"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016152 - mercury (II) reductase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA];
                     GO_process: GO:0050787 - detoxification of mercury ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="HFD3635149.1"
                     /translation="MNKFKVNIQGMTCTGCEKHVESALEKIGAKNIESNFRRGEAVFE
                     LPDDIEVESAIKAIDEANYQAGEIEEVSSLENVALINEDDYDLLIIGSGAAAFSSAIK
                     AIEYGAKVGMIERGTVGGTCVNIGCVPSKTLLRAGEINHLSKDNPFKGLQTSAGEVDL
                     ASLITQKDKLVSELRNQKYMDLIDEYNFDLIKGEAKFVDASTVEVNGAKLSAKRFLIA
                     TGASPSLPQISGLEKMDYLTSTTLLELKKIPKRLTVIGSGYIGMELGQLFHHLGSEIT
                     LMQRSERLLKEYDPEISESVEKALIEQGINLVKGATFERVEQSGEIKKVYITVNGSKE
                     VIESDQLLVATGRKPNTDSLNLSAAGVETGKNNEILINDFGQTSNEKIYAAGDVTLGP
                     QFVYVAAYEGGIITDNAIGGLNKKIDLSVVPAVTFTNPTVATVGLTEEQAKEKGYDVK
                     TSVLPLDAVPRAIVNRETTGVFKLVADAETLKVLGVHIVSENAGDVIYAASLAVKFGL
                     TIEDLTETLAPYLTMAEGLKLAALTFDKDVSKLSCCAG"
     gene            3326..4648
                     /locus_tag="ACF3UE_001752"
     CDS             3326..4648
                     /locus_tag="ACF3UE_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFD3635150.1"
                     /translation="MSDLLSLPDIKTIEPPQENETDMMFKVEAVGPPERCPECGFDKL
                     YKHSSRNQLIMDLPIRLKRVGLQLNRRRYKCRECGSTFWERLISVDEKRSMTKRLLKS
                     IQEQSMSKTFVEVAESVGVDEKTIRNVFKDYVALKEREYQFETPKWLGIDEIHIIRRP
                     RLVLTNIERRTIYDIKPNRNKETVIQRLSEISDRTYIEYVTMDMWKPYKDAVNTILPH
                     AKVVVDKFHVVRMANQALDNVRKSLKAHMSQKERRTLMRERFILLKRKHDLNERESFL
                     LDTWLGNLPALKEAYELKEEFYWIWDTPDPDEGRLCYSQWRHRCMSSNSKDAYKDLVR
                     AVDNWHVEIFNYFDKRLTNAYTESINSIIRQVERMGRGYSFDALRAKILFNEKLHKKR
                     KPRFNSSAFNKAMLYDTFNWYEVNDHDITDNFGVDFSTLIKNLEKGDL"
     gene            4673..4936
                     /locus_tag="ACF3UE_001753"
                     /pseudo
     CDS             4673..4936
                     /locus_tag="ACF3UE_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043131.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(4983..5213)
                     /locus_tag="ACF3UE_001754"
     CDS             complement(4983..5213)
                     /locus_tag="ACF3UE_001754"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635151.1"
                     /translation="MNKVHVYNHNKFVKEINSDTNSIAKEIASQSPFAELKMTDEYDN
                     LILTTKGFFLDDVPNQIWLKNELMPALTNLQI"
     gene            complement(5483..5968)
                     /gene="vanZ-A"
                     /locus_tag="ACF3UE_001755"
     CDS             complement(5483..5968)
                     /gene="vanZ-A"
                     /locus_tag="ACF3UE_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFD3635152.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(6121..7011)
                     /locus_tag="ACF3UE_001756"
     CDS             complement(6121..7011)
                     /locus_tag="ACF3UE_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFD3635153.1"
                     /translation="MLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLENSGTSE
                     NTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDSNIYMS
                     KEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEHNSGL
                     SLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIRYVGLPHS
                     AIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEISGN
                     NIDGVIVTVFPGSTHTNSRR"
     gene            complement(7461..8069)
                     /locus_tag="ACF3UE_001757"
     CDS             complement(7461..8069)
                     /locus_tag="ACF3UE_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFD3635154.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(8075..9106)
                     /gene="vanA"
                     /locus_tag="ACF3UE_001758"
     CDS             complement(8075..9106)
                     /gene="vanA"
                     /locus_tag="ACF3UE_001758"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFD3635155.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(9099..10067)
                     /locus_tag="ACF3UE_001759"
     CDS             complement(9099..10067)
                     /locus_tag="ACF3UE_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFD3635156.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            complement(10282..11436)
                     /locus_tag="ACF3UE_001760"
     CDS             complement(10282..11436)
                     /locus_tag="ACF3UE_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFD3635157.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            complement(11414..12109)
                     /gene="vanR-A"
                     /locus_tag="ACF3UE_001761"
     CDS             complement(11414..12109)
                     /gene="vanR-A"
                     /locus_tag="ACF3UE_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFD3635158.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            complement(12381..13694)
                     /locus_tag="ACF3UE_001762"
     CDS             complement(12381..13694)
                     /locus_tag="ACF3UE_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003141076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HFD3635159.1"
                     /translation="MATLHENRLLFNSNVTVSHSGGNLSSDSGLILAKEFMNKFEFSQ
                     ILCKNIQIQDDRLYHVHENESILEQIILQLIAGYPTDSSANILATDPIFQAVLSKKRL
                     ASQSSISRFWDRISTENIVQLQKVNQILIDKARTIRNTNEMIFDLDSTHSDTFGNQEM
                     TDYNAHYQTTGYHPLVAFDGLTGDFLKAELRSGNVYTSKGVAAFTRPLFEHYHSVTPV
                     STIMVRADSGFAMPDLYELCEEYDSLYTIRLKSNRNLYRIADQFITIKDHHDWSKKEV
                     HYYNATYQAKSWGKSRRICIKSTREASELLFRHEFIITNFSKDVSPEMVFQTYSKRGT
                     MENYIKEAKNGFYLDKTDSPRFIENHARMIVSLLAYNIVNFMRTLCFTNETKGYQVST
                     IRLFLFKIAGKIVHSGRRQYLKLSSYHVYQKLFYRILQNIQVLQC"
     gene            complement(14003..14578)
                     /locus_tag="ACF3UE_001763"
     CDS             complement(14003..14578)
                     /locus_tag="ACF3UE_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3635160.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            14724..17690
                     /locus_tag="ACF3UE_001764"
     CDS             14724..17690
                     /locus_tag="ACF3UE_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HFD3635161.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            complement(17774..17959)
                     /locus_tag="ACF3UE_001765"
     CDS             complement(17774..17959)
                     /locus_tag="ACF3UE_001765"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635162.1"
                     /translation="MSTLQEKQLQFNPHLLRNEEIFRGASIYKIITIDMMKQIKARDK
                     QIELAENIVDYLLHTNF"
BASE COUNT         5743 a         3355 c         3319 g         5689 t
ORIGIN      
        1 gcccaaaaaa agaaagaaga aaactgtttc tgatattgaa cttcaaatta aagaattaca
       61 aaagaaaaaa gaagaattaa ttctaaaatc aaaagcagat attggtgatt ttgtcctttc
      121 tactctttca aaacttgata tttctattga atcgattgaa gaaaacaaag aattattcta
      181 tgacgaatta gaaactttat taaatgcgaa tagtcaaaat ttttctgaat tacttaaata
      241 gttatggcaa ataatgattt aaatgacatc aacaaaagaa tagaaaaact aaaaattcaa
      301 aaaaatattt tgcgagcgaa tagcgagcaa aatattaaca gaaaaagaag aacaaaacgt
      361 ctaattgaaa aaggtgcttt gttagaaaag tattttgaaa ttgactattt aactgtagaa
      421 gaaacggaag aatttttaaa aattttttct gaatatatta aagcgaataa acctaaaaag
      481 tatcaaaaaa aggaaaaata attttccttt ttttgatact tttttaaata aaattgattg
      541 ttcttaatgt ttgtccttcc ttttttaatt gctttaatat ttcatttact gattctatat
      601 ccaaatcgta ccaatcacca aaagcgataa tatcacctga tacttttttt tctataaaat
      661 caactgttaa agttatttct cttgttgaca ttggcgaacg tgcttctatt tgatataaat
      721 caaaatcgta tttttgatga ttatttattc ctctcatttc tgttactgtc gcttttataa
      781 cttttaaaat attaccttca aaatttattt tgggtcttcg gaatatatag tggaattact
      841 ttcttaatag tttaaaaaca actggtgttt aaatcggatt ttctggtggg atgttaggac
      901 aatcaatagt attatataaa agtatcaatc acatacgagt gatacgttgg ggaaaaataa
      961 aatagtccaa tttacttgac cgcgtactat ggtacacggt ttataatatt catggggtga
     1021 aataagatga tttatcgcat tagtgagttt gcagataaat gtggagttaa taaagaaacg
     1081 attagatatt acgagagaaa aaatttatta caagaacctc accgaacgga agctggttat
     1141 cggatatatt catatgatga cgttaagcgt gttgggttta ttaaacgaat acaggaactt
     1201 agtttttctt taagcgagat ttataaatta cttggtgttg tagataaaga tgaagttcgt
     1261 tgtcaagaca tgttcgaatt tgtttctaaa aaacaaaagg aagtgcaaaa acaaatagag
     1321 gatttaaaac gaattgaaac tatgttagac gacttaaaac aacgatgtcc agatgaaaag
     1381 caattacatt cgtgtccaat aatagaaaca ttaacatgag acattaacga aaggggcttt
     1441 tttatgaata aatttaaggt aaacattcaa ggaatgactt gtacgggttg tgaaaaacac
     1501 gtagaatcag cacttgaaaa gataggtgct aaaaatattg agtctaattt tcgtcgtggt
     1561 gaagcagtat ttgaactgcc cgatgatatt gaggttgaaa gtgcaataaa ggcgattgat
     1621 gaagcaaatt accaagccgg agaaattgaa gaagtatcat cactagaaaa cgtggcgtta
     1681 attaatgaag atgattatga ccttcttatt attggttctg gtgctgctgc cttttcttcg
     1741 gcaattaaag ctatagaata cggtgcaaaa gttggaatga ttgagcgtgg aacggttggg
     1801 ggaacctgtg tgaatattgg ctgtgttccg tcaaaaactc ttcttagggc aggggaaatc
     1861 aatcatttat caaaagacaa tccgtttaaa ggtttacaaa catccgctgg agaagtggat
     1921 ttagctagtt taatcacgca aaaggataaa ttggtgagcg aacttcggaa tcaaaaatat
     1981 atggatttaa ttgatgaata taattttgat ttaattaaag gtgaagcaaa attcgttgat
     2041 gctagtacgg ttgaggtcaa tggggcaaag ttatctgcaa aacgcttttt aattgcaaca
     2101 ggtgcatcgc cttcgttgcc ccaaatttca ggacttgaaa aaatggacta tttaactagt
     2161 acaacacttc ttgagttaaa gaaaatacca aaacgattaa ctgtaattgg ctcaggatac
     2221 attggaatgg agcttggaca actatttcat catttaggtt cagaaataac gcttatgcaa
     2281 agaagtgagc gacttttaaa ggagtatgat cctgagattt cagagtcagt tgaaaaagcg
     2341 ttaattgaac agggtataaa ccttgtcaaa ggggcaactt ttgagcgtgt tgaacaaagt
     2401 ggagagataa aaaaggttta cataacagta aatggcagta aagaagtcat tgaatcagat
     2461 cagttacttg ttgccactgg aagaaaacca aatacggatt ctttaaattt aagtgcagca
     2521 ggtgttgaaa ctggaaaaaa taatgaaatc ctgatcaatg attttggtca aacaagtaat
     2581 gaaaagattt atgcagcagg agatgtgacg ttaggaccgc aatttgtata tgtagcagcc
     2641 tatgaaggtg gaattattac tgataatgct atcggtggat taaacaaaaa aatagattta
     2701 tcggtagttc ctgctgttac gtttacgaat ccgacggttg caacggttgg tttaacagaa
     2761 gaacaagcaa aagagaaagg gtatgatgtg aagacatctg tattaccttt agatgctgtt
     2821 ccaagagcaa ttgtaaaccg tgaaacaacc ggtgtattta aactagtagc agatgcagaa
     2881 acactaaaag tattaggggt tcatattgta tctgagaatg caggagatgt catctatgca
     2941 gcatcattag ctgttaaatt tggcttaacg atagaagatt taacagaaac cctagcacca
     3001 tatttaacaa tggctgaagg gctaaaatta gctgcactta cgttcgataa agatgtttcg
     3061 aaattatctt gttgtgcagg ctaagggaac tttttttaca actccctatt caagtgaacc
     3121 agctaatact gtactaaagg tgtgcagtag tttagcaaag tctacaaaag atttcataca
     3181 ctattttgcg atcacccatt atataaatgc tttaagggat tttctaagtg catttgtggt
     3241 cacaaaaata atttaacaat gatgatttcg acatcaaatc tataattgat accttaacac
     3301 cgcagagtaa taaaggatga acaatatgtc agacttatta tccctaccag acattaaaac
     3361 aatagaacca ccacaagaaa atgaaaccga tatgatgttt aaagttgaag cagtcggacc
     3421 acctgaacgt tgtcctgaat gtggttttga caagttgtac aaacacagtt caagaaatca
     3481 actaattatg gatttgccca ttcgtttaaa gcgagtgggc ttacaattga accgtagacg
     3541 atacaagtgt cgtgaatgcg gatctacctt ctgggaacgc ctaatatctg tagatgaaaa
     3601 gcgtagtatg accaaaaggc ttttaaagtc cattcaagag caatccatgt ctaagacctt
     3661 tgtagaagtc gcagaaagcg ttggtgttga cgagaaaact attaggaacg tttttaagga
     3721 ctatgtggca ctcaaagaac gtgaatacca gtttgaaact cctaagtggc ttgggataga
     3781 cgagatacat attatccgta gacctcggct tgtattgact aatattgaac gcaggactat
     3841 ttatgacatc aagccaaacc gtaacaagga aacagtcatc caacgtcttt cagaaatcag
     3901 tgacaggact tatattgagt acgtcacaat ggatatgtgg aagccttaca aagacgcagt
     3961 gaacactatc cttccacacg ctaaagttgt cgtagataag tttcatgtag ttagaatggc
     4021 taatcaagcc ttagataacg tcagaaagtc tttgaaagcc catatgagcc aaaaagaaag
     4081 acgtaccctt atgcgtgaaa ggtttatcct tctaaagcgt aaacacgatc taaatgaacg
     4141 tgaatcattc ctcttagata cttggttagg taatcttcct gctttaaaag aagcctatga
     4201 actcaaagaa gagttttact ggatatggga tactcctgat ccagatgaag gtcgtctttg
     4261 ttatagtcaa tggagacacc gttgtatgtc cagtaactct aaagacgcat ataaagacct
     4321 cgtgagagcc gtagacaact ggcatgtcga aatattcaac tactttgata aaaggctcac
     4381 taacgcttat acggagtcaa ttaacagtat tattaggcag gtagagcgaa tgggtagagg
     4441 ttactcgttt gatgccttac gagccaaaat ccttttcaat gagaagctcc ataaaaagcg
     4501 taagccacga tttaattcaa gtgctttcaa taaagctatg ttatacgata ctttcaattg
     4561 gtatgaagtg aatgatcacg acattacaga caactttggt gtcgattttt ccacacttat
     4621 taagaatttg gagaagggtg atttataagc ccttttccac catgaaatcc gaatacccga
     4681 aatatataaa tatcaagcag aatctgaacg aaagaatata aaagaaagac aagcccaggg
     4741 aataaagatt gctaaagacg gtaaaaaata tagaggtaga aaacctttat ttacaaagga
     4801 tagccctaga ttacagcatg cttttgaatt atataagaat ggatattcag acaaagaggt
     4861 tcaaaattta actggtatta atcatgaaac atttagaaga tataggatta aacataatat
     4921 tcaacgcaat atataaaata acctcaccta attatactaa tgtgatcagg tgaggttatt
     4981 ttttaaatct gtaaatttgt aagagctggc attaactcat tttttagcca tatctgatta
     5041 ggtacatcat ctaggaaaaa gccttttgtt gttaaaatta agttatcgta ttcatctgtc
     5101 atttttaatt cagcaaatgg ggattgacta gcaatttctt tagcaatgct attcgtgtcg
     5161 ctattaattt cttttacaaa tttattatga ttatatacat gtaccttatt cattttattt
     5221 attctccttt atggggtacc gtcaggaaaa tgcggattta caacgttaag gaaatttatt
     5281 aaagagacca attcctcagc actaaaattg ataattgggc tttctttgtt actatagtgt
     5341 taggtaagct ttttacttta tcaccggttt tcccctcact tcacacctac gggcgagttt
     5401 ccccacatcc cgttttccat ctaatccaat tcattcaata tctttatgtg tatgaaagat
     5461 cagattgctt gatttagaca tcttacacgt aatttattct taaatgggta cggtaaacga
     5521 gcaataatac gagcaaaagt atacctacaa aaataataac tctgtctaat tttttttgat
     5581 tcatatgctt attgcttaaa ccatataatt tcagtccaag aaagcctcca acagtatttg
     5641 taattacatc tgttatgtct gtcgctccaa tagcgaagat aaattgaatt atttcaaaag
     5701 taagacttaa aaccagtaca aaagcaaact taggtaaaaa tccgatttct ttaaaattga
     5761 cattcaaaag caagccaaat ggaataaaga ttataacatt atctatcatc tctctgaaat
     5821 tcccagtagc agtaaatgga gtcaagttaa gacttctttg atgataatta aatactgata
     5881 aaatattgta ttgtaatttg aataacacta accagattag tgtcactaaa tataaagcta
     5941 gcaatcctct agataatatt tttcccaata taatttcctc taattctttt gtttaagttg
     6001 tatcattagt atagcaatgt cctagttaac gtgggtttta aattaaaaag ctaacgttac
     6061 cccaaaagtg ctagtacaat aatgctgttc attaatttcg ttggtttcat tccgccatcc
     6121 ttacctcctt gaattagtat gtgttgatcc gggaaacact gtcacaatta caccgtctat
     6181 attgtttcct gatatctcat aacgaagatt agtcggcaca tgaatggtgg tatttttagt
     6241 aacaggataa taaaagatct catatttttc cccatttaca ctaacagaaa tggttttttc
     6301 ttcttttagg taatccatat attcctcgag aacgaaattc ttttctttca taatcgcact
     6361 atgtggtaaa ccaacatagc gaatatgcca tggttcatat tgaattcctg ttaactctgt
     6421 tttgtcctct ggataacgta aaatgaaccc gtatttccaa gcattttctt ctatccactt
     6481 tccttcaggg gctcgttcca ttttcgtcaa gcttgatcct acatctagtg ataaacctga
     6541 attatgctca ctataacctg ctggtaaggc atactcagcc cccatttctt ggtaaagcac
     6601 actttgctca tcaaagtctc gatagccact attaataata aaatgactaa cgccaccctt
     6661 tacagcatca ttgaccatct ctgaaaattt ttgtgctatt tcttttgaca tataaatatt
     6721 actatcaagc aacccgtatc catttattaa ttcgtcatgt ttagataaat tcacgatatc
     6781 tgacttcaca ctttcttggc gaacaggata tttactattg attaatagca gatttccttg
     6841 ataaacctgt tcttctgtaa ttgttttctc ttgggtattt tcagaagtcc cactattttc
     6901 taaatgttct ttgggatttt gatcataatt ttgaaattcg actttttcct gagaaaacag
     6961 tgcttcatta acgtagtcat aacctaagta tattaagaat aacaataaca ataaaaaaaa
     7021 acaacttctt cattttcagt ctcctcctta actatatagt tggaagtatg aaatatttct
     7081 agaatcttcc ccttaaacgg cacaatctcg tttgagattg tgccgttttg ccccgtaaat
     7141 tacagtcaat tatttcgccc tactggattt actattatca ccaatgtaga tgaattttca
     7201 taagtgatac ccatgctgaa tttaacgagg ctgaactgcc tgttgacaat gggcggtgtg
     7261 aaataccacc cctctatgcg atcagtctta ttatcaggct atcttgccgc agcgcacgca
     7321 gataatgacc gcaatatcgc tctgccttac atcttcaata ctatctacta tatataaatt
     7381 ccctaagaac cagttacata cgtcgggttt cctgccgaaa gagttagctt atatagtttg
     7441 tccgtgcaac ggttaaaagt ttatttaacg gggaaatcaa aatagctatt ggggtatggt
     7501 tcgtctctta atacatagtg ccaccattcg aggctatatg cttcaaaccc actgttttcc
     7561 atgatggagc gcaaacgtct gcgattttgc gcttcattgc atgatattcc atttgccgca
     7621 tgatgagagc gttcatccat aaaatcaaat cggctcccca ttggtacaag ctcacccgtg
     7681 tctaatcgat aaagcgtaag atcaatggca ctgccgcggc tatggcttga ttttgaagcc
     7741 acgtatcctt ttgaaatcat ctcagttcgg tcaatattgg gataataact ttcctttgtc
     7801 aggttatttt ccggctgtgc agcccattgc ataaaacagt ttacagcacg cttaggacgg
     7861 taaccgtccc atagaagcaa tccgtaccct tgggtagcag ccagttcttt tgccttcaaa
     7921 agcgattcag ccaactcgta tgtccctaca atgcgattta cttcataacc gtcaaccggt
     7981 tttccggtga aattatccca agtggcatat ttagcgtccc aacgaacacc gtgtactatt
     8041 tcatctaaaa aagtaaatcc tatttccatg cttatcaccc ctttaacgct aatacgatca
     8101 agcggtcaat cagttcggga agtgcaatac ctgcagcggc catcatacgg ggataacgac
     8161 tgtatgacgt gaaaccgggc agagtattga cttcgttcag tacaatgcgg ccgttatctt
     8221 gtaaaaacat atccacacgg gctagacctc tacagccgag cgctttatat attttttttg
     8281 ccgtttcctg tatccgtcct cgctcctctg ctgaaaggtc tgcgggaacg gttataactg
     8341 cgttttcaga gcctttttcc ggctcgactt cctgatgaat acgaaagatt ccgtactgca
     8401 gcctgatttg gtccacctcg ccaacaacta acgcggcact gtttcccaat accgcacaac
     8461 cgacctcaca gcccgaaaca gcctgctcaa ttaagatttt gctgtcatat tgtcttgccg
     8521 attcaattgc gtagtccaat tcgtccgcgc tattgacttt tttcacaccg aaggatgagc
     8581 ctgaacgcgc cggcttaaca aaaacaggat aggtaaacgt agctgccacc ggcctatcat
     8641 ctttattaat aacccaaaag gcgggagtag ctatcccagc atttttcgca acgatgtatg
     8701 tcaacgattt gtccatacaa attgctgagc tttgaatatc gcagcctaca aaagggatac
     8761 cggacaattc aaacagacct tgtatggatc catcttcacc tgacttgcca tgcaaagctg
     8821 aaaatgctac atcaacatgg ttgatttcat attcatggtt ctttttaaca agtaatccgt
     8881 gcattttttt atccggcgag agtacagctg aatagcaatt gtcgttttcc cattccgcgc
     8941 aaggtttttc gcacattttc catacaccag atttcgtaat tccaatgtat aacggctcgt
     9001 atttttcttt attaatgtta gcggctatct ctattgcaga ttttaccgat acgtcatgct
     9061 cctctgagca acccccaaac agtattgcaa cttttattct attcatgctc ctgtctcctt
     9121 tcaaaatcca aacagttttt aatggttttt tcaacggtat cacgcaacgc ttgctcggta
     9181 taataggccg tatgcggtgt gattatcacg ttaggcattc tttgaagttt aagtaaaaat
     9241 tgattatcaa ttggtttttg ggtgcaatca gagtagaaaa actcttcctc tccttccaat
     9301 acatccaatg cggcaccgcc cagtttcccg ttttctaatg ctttaaccaa ctcataggta
     9361 tctacaagtg gaccgcgccc agtattgata agaaatgctc cttgcttcat tctctgtatt
     9421 tgttcgtggc tgataatata gtgcgtatcc gtattgagcg gcacatgaag cgtaacgata
     9481 tcgctatttt gcagcaactc atcaaacggt acatagttta cctctatact tcggctgcga
     9541 ctataagcca acactttaca tccaaatcct cgcagccgct caataaccgc tttgcctatc
     9601 tggcccgttc ccaccacacc aactgtcatg tcgctgagta ccttgccacg gtcgctgtcc
     9661 aacctgaaat catgtttttc cacagagcgc acaatcgatt ttacgttgcg tactgccata
     9721 agaattagca tcatagtata atcggcaacg ctatccggcg agtacgccac attgtcgaca
     9781 gtgatgccca ttctcttagc agcagttgta tctatatgat tgcagccgat gcttcgggta
     9841 gaaatatatt tcacaccggc tctcttcagc gcaagaagaa tagaggcgga aatctctgat
     9901 ttatgtccca cactgataca ttgattgaaa ggcgcggatt tggcgttgga ttccgacacg
     9961 ttggcgttaa ttatcgttgc cataacgcca aagcgaggcg aaagagcatg gaatgcatct
    10021 gcctcatcct gctcacatcc ataaacagta atgccgatgt tattcataat taagaccaac
    10081 cctttctgtg aaaggcacca aataaaacgg ggatgccaat ggtaatcttg tcaaatcttt
    10141 ctctgaagaa cgaaaacggc tcgttcttac ggtattaagt ctaccgtgta agaacgagcc
    10201 gtttcttaat attaaattgt taatttccta agaaaaagta aagataacct tgagattttc
    10261 ctaaaaaatt atatacatct cttaggacct ccttttatca accaagtctg gcatcgctgg
    10321 aagctctacc ctaaacgtcg tatagttatc attgctttcc gcgtaaatct gccctccatg
    10381 ctgaacaata atttcttttg caatcgccaa tccaagtccc gcgccacccg tatcggaaga
    10441 acgagcattg tccagcctat agaacttttc aaatatggca gctagcttat cttttgggat
    10501 gcttccagtg ttcttgaatt cgattgacac cacatccccg gagaggcccg cggtaatgtc
    10561 aatgatgctg ttatcctcac tgtatgcagc ggcgtttttc aaaatgttgt taaagactct
    10621 cgcgagttta tcagggtcgc cggacacggt cagatcctcg ggggcgtgaa taaccgcctg
    10681 ttttccatgt gcggaaagct gaggataaaa ttcatcggtc atctgcacca gcatatagta
    10741 taggtctatg tgcgtttttg ttagcgttat cgtttgtagg ttataccgtg taatctcaaa
    10801 aaactcgtcg attagctgtt cgagtcgata cgctttgtcc aacgtgatat gcacatactt
    10861 tgccttttga tctaccggca tgtctggagc ctcgtcaagc aggctcaaat aaccgataat
    10921 ggatgtaagg ggcgttttaa tatcgtgcgc caagtacata acaacgtcat tttttctttg
    10981 ttcggccagc tttgcatcct gctctcgctt ttccagagtc cgttttaatg tgttgagctt
    11041 ttgttccata acatccattt ccgcagaaag ctcaatttgt ttatcttcgt tctgaataag
    11101 tacatcaatg ccggtattta tctcgtcaaa gtattttgcg aattttgaaa gcatgacgcg
    11161 acatagaata agaatactaa tgacaatcgc cacataaata aagatatcta tattgttccg
    11221 tatggaatat tgatataatt tcatcgcgtc caggtgattt aagtcatatt tgttttccaa
    11281 aatacttaag atccaatccc caagtttccc tcggatcatt gaacgaatat acaacacgaa
    11341 tacaattgct accacaacaa ttgcaacgat atacatgtaa agttttcgtt ctagtttgga
    11401 atagtcgttt tttttatttt tcaattttat aaccaacccc ccataccgtt tttatatatt
    11461 tcggattatc aatggtgtcg ttcatttttt cgcgcaaatg ccggatatgc acggtgatgg
    11521 tgttgttgct cttgctgaaa tattcgtcgc cccatatctc atgaaatagc agctcggagc
    11581 taaccacatt ccccttgttt tcacagagga ttcgcagtat tgaaaactcg gtgggagtaa
    11641 gggataactg cttctcgttc agataacact catgggtgtt aacattaatg acaaggccgg
    11701 agtggacgat aacattttcg ttctgctcct ttactccact gaattttttg tatcggcgca
    11761 actgggcctt tacccgagca attaactcca gtgggcgaaa gggcttcgtt atataatcat
    11821 ccgcgccgat tgttaaccct gtaattttat ctacctctgt atctttcccg gtcagcatga
    11881 taatcggata ggtgtgcttg tcccttattt tttgacagat agtaaggccg cttgtgccgg
    11941 gaagcatgat gtccaatatg gcaaggtcaa tctcagactt gtctatacat tccaatgctt
    12001 ctttggcggt atagtatttg aaaaccgtat aattctcgtt ttttaagtat aattcaacca
    12061 aatcggcaat ttcatgttca tcatccacaa taagtatttt atcgctcata gttatcaccc
    12121 tttcacataa gtttgccctt aataatttat cagattatag ggccgaattt atacctgaat
    12181 aattcatact ttttataaac taccaaattt tataattatc tgtttagttt tatgctcaat
    12241 ggttcttttt ctcaaaaata tttttctaaa gggtttaatt tatttttgct aactgattaa
    12301 gttcaagaaa gacctcattt tgggcgcact catcctatcg gatggttaac gaattttttt
    12361 gaatggcgca ataaacgcaa ttaacactgc agtacctgaa tgttttgtag aatccgataa
    12421 aatagcttct ggtaaacatg gtaactactt aatttcaagt attgtcttct tccggaatga
    12481 actatctttc cagcaatttt aaagagaaat aagcgaatag tagaaacctg ataccctttc
    12541 gtttcattgg taaaacacag tgtccgcatg aagttcacga tattgtaagc caataggctt
    12601 acgatcatac gagcatgatt ttctataaaa cgtgggctat ctgttttatc caagtaaaag
    12661 ccgttttttg cttccttaat gtaattttcc atcgttcctc tttttgaata cgtttggaaa
    12721 accatttctg gagagacgtc ttttgaaaaa ttagtaatga tgaattcatg tctaaaaagc
    12781 aattcactag cttctctggt tgattttatg cagatccttc tggattttcc ccatgacttt
    12841 gcttgataag tggcgttata gtaatgaact tctttcttac tccaatcgtg atgatcctta
    12901 atggtaatga attgatcagc gattctgtac agattacgat tggatttcaa acggatagta
    12961 tacaaactat cgtactcttc acaaagctca tacaaatcag gcattgcgaa tccactatct
    13021 gcacgtacca taatagtgct tactggtgtc acagagtgat aatgctcaaa taatggacga
    13081 gtaaatgctg cgacgccttt tgaggtgtag acatttccag aacgaagttc tgctttaaga
    13141 aagtctccgg taagaccatc aaaggcaacg agtggatgat aaccggttgt ctggtaatgc
    13201 gcattataat cggtcatttc ttggtttcca aaggtatcac tgtgagtaga atctaaatcg
    13261 aaaatcattt cgttcgtatt tcgaatcgtc cgtgctttat caatcaaaat ctggttaacc
    13321 ttttgtagct ggacgatatt ttctgttgat atccgatccc aaaagcgaga aatggatgac
    13381 tgtgaagcca accgcttttt gcttaaaaca gcttgaaaga taggatccgt tgctaatata
    13441 ttggctgaag aatctgtagg atagcctgca atcaactgca agatgatttg ttccagaata
    13501 gattcatttt catgaacatg atacagtcgg tcatcttgaa tctggatgtt tttacataag
    13561 atttggctaa actcaaattt gttcatgaat tcttttgcta atattaagcc ggaatctgag
    13621 gacaaatttc caccagagtg agatactgta acatttgaat tgaaaagtag acgattttcg
    13681 tgtaaagttg ccattgagag aacccctttc tttggttagg tttagtcact ttaaccatag
    13741 cagattgggg ttctttttgt acacccaaag ggtgcgaata aacgaaacaa aatagactgt
    13801 tataacaagg tttttgaaac gtttttgaaa aactatgaat tattcaggtt ataagcattt
    13861 acataataaa tgactaagaa tttcttaaga tgatgattct ttttttatca aagggctttt
    13921 cggcatcgct aggaggctgt taatatttta tagtttcctt ttcttcttta aaaatattgc
    13981 ccattagcgg aatacagaat ggctaattat tcacttctga taatttcctg tataatgaag
    14041 ccctagatac attagtaatt tcacaaattt gatttacagt catatttcct tctttatata
    14101 gctttaccgc ataattcatt cctgcgtgat ttttatgata cttctttaat cgacctttaa
    14161 actttccttc tttcttagcc aattcaatcc cttcacgttg tctcatccga ataagatctc
    14221 gctctaattg gttaacacca gccattacag taattaagaa ttggctgtat ggattatctt
    14281 ctgataaatc aagccatgta tcttttagtg attttaaact tgccttttta tctcgtatgt
    14341 tatcgattaa ttcaaataga tcttgtgtac tacgagtgat tcgagttaag tctgtaacat
    14401 aaatgatgtc atcttcctgt aaatcgtcta acactttttg aagttgctcg cgatcctttg
    14461 ttgctcctga aactttctct tcatatataa tatccattcc gatctcgttc aactgctgaa
    14521 attgtcttga aggattctgg ttagtcgaac tgacacgaat ataaccgatt ttccgcaaaa
    14581 tatcacctca tttttgagac aagtcttatg agacgctctt aactatgatt ttatcagtct
    14641 actacatttg tatcaataga gtacactcta ttgatatata attgaactaa taaattgaaa
    14701 atacagaaat ggaatgatac tgaatgaaaa ttgcgagagg tagagaattg cttacaccgg
    14761 aacagagaca ggcttttatg caaatccctg aagatgaatg gatactgggg acctacttca
    14821 ctttttccaa acgggattta gaaatagtta ataagcgaag gagggaagaa aaccgtttag
    14881 gatttgctgt tcaattagct gttcttcggt atcccggttg gccatacact catatcaaaa
    14941 gcatcccaga ttcggtcata caatatatat cgaaacagat tggtgttagt ccatcctcgc
    15001 ttgatcatta tcctcaaagg gaaaatacac tttgggatca tttgaaagaa attcgaagtg
    15061 aatacgactt tgtaactttt accctgagtg aatatcgaat gacatttaag taccttcatc
    15121 aattagcttt ggaaaatggt gatgccattc atctactgca tgaatgcata gattttctaa
    15181 gaaaaaacaa aattatactg cctgctatca ctacacttga aagaatggtg tgggaagcaa
    15241 gggcaatggc tgaaaagaag ctatttaata cggttagtaa atctctaaca aatgagcaaa
    15301 aagaaaagct tgaagggatt attacctcgc agcatccatc cgaatccaat aaaacgatat
    15361 tgggttggtt aaaagagcca ccgggtcatc cttcacccga aacttttcta aaaataatag
    15421 aacgactcga atacatacga ggaatggatt tagaaacagt gcaaattagt catttgcacc
    15481 gtaaccgcct gttgcagctg tctcgcttag gctcaagata cgagccgtat gcattccgtg
    15541 actttcaaga aaataaacgt tattcgatat taaccatcta tttattacaa cttactcagg
    15601 agctaacgga taaagcgttt gaaattcatg ataggcaaat acttagtttg ttatcaaaag
    15661 gtcgtaaggc tcaagaggaa atccagaaac aaaacggtaa aaagctaaat gagaaagtta
    15721 tacactttac gaacatcgga caagcattaa ttaaagcaag agaggaaaaa ttagacgttt
    15781 ttaaggtttt agaatcggtt attgaatgga atacctttgt ctcttcagta gaagaggctc
    15841 aggaacttgc acgtcctgcc gactatgatt atttagactt actgcaaaaa cggttttatt
    15901 cactaagaaa atatacgcca acgctattaa gagtattgga atttcattct acaaaggcaa
    15961 atgagccact tttacaagct gttgagatta tccgaggaat gaacgaatct ggaaagcgaa
    16021 aagtgcctga tgactcacct gtggatttta tttcaaaacg atggaaaaga catttatacg
    16081 aggatgatgg tacaacaatt aatcgtcatt actatgaaat ggctgtttta acagaacttc
    16141 gggagcatgt tcgggcagga gatgtttcca ttgttggcag cagacaatat agggattttg
    16201 aggaatattt gttttcggaa gatacatgga atcaatcgaa ggggaatacg agattatcag
    16261 ttagtttatc attcgaagat tatataacgg agagaaccag cagctttaat gaaaggttaa
    16321 agtggttagc tgccaattcc aataagttag atggggtttc tcttgaaaaa ggaaagctat
    16381 cacttgcacg cttagaaaaa gatgttccag aagaagcaaa aaaatttagt gcaagccttt
    16441 atcagatgct accaagaata aaattaactg atttactcat ggatgtggcc catataacag
    16501 gatttcatga gcaattcact catgcttcca ataatcgaaa accagataag gaagaaacaa
    16561 tcattatcat ggctgccctt ttaggaatgg gaatgaatat tggcttgagc aagatggccg
    16621 aagccacacc cggacttaca tataagcaac tagccaatgt atctcaatgg cgcatgtatg
    16681 aagatgccat gaataaagcc caagccatat tagtaaactt tcatcataaa ttacaattgc
    16741 ctttctattg gggcgacggt acaacatctt cgtcagatgg tatgagaatg cagctaggtg
    16801 tttcatcact acatgcagat gcaaatccac attatggaac tggaaaagga gccaccatct
    16861 accgatttac aagtgatcaa ttctcttctt actacacaaa gattattcat actaattcaa
    16921 gagatgcgat tcatgttttg gatggtttgt tacatcatga gacggatcta aacatagagg
    16981 aacattatac agacactgcc ggttacactg accaaatatt cggactgact catttattag
    17041 gatttaaatt tgccccaaga ataagggatt tatcggactc aaaattattt acgatagata
    17101 aagcaagtga gtatccaaaa ctagaagcca ttttacgtgg acaaataaat acaaaggtca
    17161 ttaaagaaaa ttatgaggat gttttgcgat tagctcattc tataagggag ggaacagttt
    17221 cagcatccct tattatgggg aagctaggtt cctattcaag acaaaacagc ttagctacag
    17281 ccttacgtga gatgggccga atagaaaaaa cgatctttat tttgaattat atatcggatg
    17341 aatcattaag aagaaaaata caaagaggat tgaataaagg agaagccatg aatggattgg
    17401 caagagctat tttcttcgga aaacaaggtg agcttagaga acgcaccata cagcatcaat
    17461 tgcaaagagc cagtgcttta aacataatta tcaatgctat aagtatttgg aatactctcc
    17521 acctaacaac agcagttgaa tataaaaaac ggacaggtag ctttaatgaa gatttgttac
    17581 accatatgtc gcccttaggt tgggaacata ttaatttact aggagaatac cattttaact
    17641 cagagaaagt agtctcatta aattctttaa gaccactaaa actttcttaa cgttgttaaa
    17701 aacgagggat tcgtcaggaa aataggctta gcgttgtaaa tccgcatttt cctgacgcta
    17761 cccctttata ttcttagaaa ttagtatgta ataagtagtc aacaatgttt tctgctaatt
    17821 caatttgctt gtctctagct tttatttgtt tcatcatatc aatcgtaatg attttataga
    17881 tacttgctcc acgaaatatt tcttcatttc tcaacaaatg gggattgaat tgtagttgct
    17941 tttcttgtaa agttgacatt gagcacacct cttgtttttg ttgttttgat cgactttaca
    18001 ataacataga gtgtgctctt tttgtatatt tttttcttca cccaacgggt gaagaaggaa
    18061 tagagtgata aaccttatca aagcgggata aatgcctgtt ctgaca
//
LOCUS       DAXLPC010000054        18056 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.054, whole genome shotgun sequence.
ACCESSION   DAXLPC010000054 DAXLPC010000000
VERSION     DAXLPC010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.054"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(29..727)
                     /locus_tag="ACF3UE_001766"
     CDS             complement(29..727)
                     /locus_tag="ACF3UE_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFD3635163.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(720..2072)
                     /locus_tag="ACF3UE_001767"
     CDS             complement(720..2072)
                     /locus_tag="ACF3UE_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFD3635164.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2295..3695)
                     /locus_tag="ACF3UE_001768"
     CDS             complement(2295..3695)
                     /locus_tag="ACF3UE_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFD3635165.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3856..4593
                     /locus_tag="ACF3UE_001769"
     CDS             3856..4593
                     /locus_tag="ACF3UE_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFD3635166.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4718..5197
                     /locus_tag="ACF3UE_001770"
     CDS             4718..5197
                     /locus_tag="ACF3UE_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFD3635167.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5194..5961
                     /locus_tag="ACF3UE_001771"
     CDS             5194..5961
                     /locus_tag="ACF3UE_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFD3635168.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6191..6760
                     /gene="lepB"
                     /locus_tag="ACF3UE_001772"
     CDS             6191..6760
                     /gene="lepB"
                     /locus_tag="ACF3UE_001772"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFD3635169.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6864..7466)
                     /locus_tag="ACF3UE_001773"
     CDS             complement(6864..7466)
                     /locus_tag="ACF3UE_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFD3635170.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7572..7802
                     /locus_tag="ACF3UE_001774"
     CDS             7572..7802
                     /locus_tag="ACF3UE_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635171.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            7793..8041
                     /locus_tag="ACF3UE_001775"
     CDS             7793..8041
                     /locus_tag="ACF3UE_001775"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3635172.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            8147..8731
                     /locus_tag="ACF3UE_001776"
     CDS             8147..8731
                     /locus_tag="ACF3UE_001776"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFD3635173.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8734..9807
                     /gene="prfA"
                     /locus_tag="ACF3UE_001777"
     CDS             8734..9807
                     /gene="prfA"
                     /locus_tag="ACF3UE_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFD3635174.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9800..10639
                     /gene="prmC"
                     /locus_tag="ACF3UE_001778"
     CDS             9800..10639
                     /gene="prmC"
                     /locus_tag="ACF3UE_001778"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFD3635175.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10632..10811
                     /locus_tag="ACF3UE_001779"
     CDS             10632..10811
                     /locus_tag="ACF3UE_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635176.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10833..11858
                     /locus_tag="ACF3UE_001780"
     CDS             10833..11858
                     /locus_tag="ACF3UE_001780"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFD3635177.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12033..13277
                     /gene="glyA"
                     /locus_tag="ACF3UE_001781"
     CDS             12033..13277
                     /gene="glyA"
                     /locus_tag="ACF3UE_001781"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFD3635178.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13430..14377
                     /locus_tag="ACF3UE_001782"
     CDS             13430..14377
                     /locus_tag="ACF3UE_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFD3635179.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14511..15140
                     /gene="upp"
                     /locus_tag="ACF3UE_001783"
     CDS             14511..15140
                     /gene="upp"
                     /locus_tag="ACF3UE_001783"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFD3635180.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15279..15521)
                     /locus_tag="ACF3UE_001784"
     CDS             complement(15279..15521)
                     /locus_tag="ACF3UE_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635181.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15642..15714
                     /locus_tag="ACF3UE_001785"
     tRNA            15642..15714
                     /locus_tag="ACF3UE_001785"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15675..15677,aa:Thr,seq:cgt)
     gene            complement(15833..16471)
                     /locus_tag="ACF3UE_001786"
     CDS             complement(15833..16471)
                     /locus_tag="ACF3UE_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFD3635182.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16594..17226)
                     /locus_tag="ACF3UE_001787"
     CDS             complement(16594..17226)
                     /locus_tag="ACF3UE_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFD3635183.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17577..17876
                     /locus_tag="ACF3UE_001788"
     CDS             17577..17876
                     /locus_tag="ACF3UE_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFD3635184.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT         6188 a         3159 c         3561 g         5148 t
ORIGIN      
        1 ttttgtcaca ttcccctttt tcgaataact aggctgtttg tccttcaaga tagggcagat
       61 ccaattcttt accgtaacgt tgttctaaag ctaggcggat caaacgagct gccaggttct
      121 catttcttgc aaggataggt ccatggaaat aagaaccgaa gacatttcgg taaatgacac
      181 cttcagattg gtcttcacca ttatttcctt gaccttgtac cactttcccc aaaggtcgtt
      241 caccttcacc taagaaagtc cgaccattgt ggttttcaaa tccataataa gtttcattga
      301 attcttcgtt atggataacg atatcaccga taaaccggtt attttcctga cttaacgtgt
      361 agtgatccag tgcactgatt ccttggatct tttctccatt agctcccatg tagtagtgac
      421 ctagcaattg gtagccacca caaatggcta acatgacgcc atcattttcg atatagttga
      481 tcaaagaatc tttctttttc tggatgtctt ttgaaatgat taattgctca aagtcttgac
      541 caccgccaaa gaaaaccaag tcatatttat cagcatcaaa aggttcatgt atactaacga
      601 tctccgtatg gcaagaaacc cccatttttt ctgctatata tttcaacatc aaaaggtttc
      661 cgttatcacc atatgtgttc atcaaatttc cataaaggtg ggcgatattg agttcataat
      721 tagccacggt tcattcctcc tttgataaat ccttgagcag ctagttcttt acgaagctgc
      781 aatacagcag tgtaagtagc taaaatatag acatgctcag ttggcaattc tttgattttt
      841 tcgattactt ctggtaattc ttttgtttct gtcaatttat tttctggaat cccggcaact
      901 tttagacgta aagtcatatc tgtatgacgg tctcctccag aaataacagc tgggatatcc
      961 atatcggcaa agttttcaaa attaccatcc caaatccagc tgacatcgat tccgtctgcg
     1021 taattggcat ttaataaagc cactaaagaa aatggataag gagctagacc aatcatatcg
     1081 attacttgat tgatacctac aggatttttg acaagtacta atgtacattt tttcccattg
     1141 atattgatga cttcttgtcg gccgaatact ttctcgtcat atcctaaacc ttgtttgatt
     1201 ttatcaggat cgacattgaa gtactctgcc actgcagtag ctgctaaagc attgtagaca
     1261 ttatacatac cgccaacttc gattccgtat tcatgaccat cgatcacgaa atctgctgac
     1321 acattgtcca tccgtaccat atcagttaat cgataatcca attcaggacg tttgaagtca
     1381 caatttggac agtaatattt ccctaagttt gcataagtga tcattttata atgcaagatg
     1441 tgatgacaat ttggacataa gacaccgtct gtattgtaat gagccatttg ttcacgatct
     1501 tcttcatggt caaagccata atattttcta ggattgactg tttcgataga attgaagatt
     1561 ggtgaatcac cgttactgat aatcgttgca tttggtgact ttgcggcacc gtctacaatc
     1621 attttatagg tcgtatagat ttctccatac cgatccattt gatcacggaa aatatttgta
     1681 aataagaaca gttctggttt catatattct gtgactttgc tcaaacttgc ttcatctatt
     1741 tctaggacag caaacttttt ctgtcctttt tttggttttg cctgcaagaa agtcgataca
     1801 attccctgta ccatattcgc accagtaggg ttggttagaa cttcatcgaa ttgctggcgc
     1861 aaaatattga ctgttaaagc ggtagtcaat gttttaccgt ttgttccggt gacaacgacg
     1921 acttggtagt cttttgccaa actatctagt atatgtggat cgactttcag cgctagttta
     1981 cctggtaaac ttgatccgcc tttaaaaaaa gtttttaatg cccattgcga cgtttttcca
     2041 actgcaatcg caaaatgact gcgtattccc attatgtaac ctccaaaaac gatttgctga
     2101 cgaataaatt caactaatca taccatatgt tgaaaaaaag gttaaattgc ttttcttatt
     2161 cttaagaaaa ggttacggct gaaagtgcat gaaatcggac aaaatcgcat gatttaacaa
     2221 aaaaacagct tgaaacaaaa tgattgtttc aagctgctgt gattttatta ttccctctta
     2281 cctatattcc cattttaacc gataataatt ttctcgcttg gatattcata gcctagatct
     2341 cgtgtttctt ttggcacgaa taacatcaat gtatatagca ttccgatccg cccaataaac
     2401 atcagtgtag caatcgtgat tttgcccaca acagacaagt ctccggtaat ccctaaagat
     2461 aaaccagttg ttccaaacgc agaagttact tcgatgatga tcgagatcag cgtttgttct
     2521 tctgtagcag ataaaaaaac gatacaaaag aaacacatac caagagaaag cataaagaca
     2581 acgactgatt ttcgcacatc atcttgatcg attctccgtc caaaaatatt gatgttatct
     2641 tcacttttga ggaaggaata tagatacaaa ccgatgattg ctacagtagt tgttcgaatc
     2701 ccgccgccta cagaactagg actgcatccg ataaacatca gtaaagaaaa aatgatcagt
     2761 gttgtgattt gaaaatcacc caaatcgtga atctgcagac cagcattacg agtcgtaatc
     2821 gaataaaaca tcgaattgat ccatttgaca ctcatattgg aatcttggaa taaatggtcc
     2881 ttttccaata gataaatcaa gacagttccc gaaacaaaca agataacaaa agctaacaca
     2941 gctaatttgg taaacaagga aaaacgaaac ggaagcttcg cattggaacg tttgtataat
     3001 agccattccc ggcactccat caatacagga aaaccaattc ctccgacaaa aatcaaaaac
     3061 atgatcagga tcaagaaaaa atagtcatgt gcaaagggct tgatggaatc cccagtgacg
     3121 tcaaacccag agttcgtgac agccgatatc gcctgataaa aaccgtaaaa aacggcatca
     3181 cgccaacgat caaaatagcc tctgtaataa aaataaatag aaaagaatgt cccaaaaagt
     3241 aattgaaacc agattaaaat agcaaaagtg atccgaatca gtcggacgat accagacaaa
     3301 cgcggttgat tcatatccgt catgatcagc tgtcgctgtt tcagtgtgat ccgtcgttta
     3361 gaaaaaatga caaaagcagt agaaatcatc atgatcccca aaccaccaac ttgaaataat
     3421 atttccagca gtataatacc gttatcattg aacacagaat tgatatcaaa agtcgatagt
     3481 ccagtcacac tcactgtact gattgccatg aacagcatgt ccacaaaaga aacatggcta
     3541 tctggttcgc gaaaaatcgg catataaaat agaacgagtg ataagaccgt catcaatata
     3601 taataaaaaa cgatgatttg gatcgatgag aaatgattgg cagcaaactt ctgtcctcgc
     3661 cgctgcagcc ttcgaaagaa taaatcaaca tgcacagtac tatcctcctg acaatagtcg
     3721 tttctaccag tatacaaggg gaattaggaa tactcaaaga aattatcaaa cagataacaa
     3781 tacagctttc gattaaaata gaaatggctt ataataagga aaatcctaga aaaaagaagg
     3841 aggaggaata acaaattgat taatgctcaa caaatcgtag aaaaaatgaa aaatcaaaaa
     3901 ataaattatg atacagttct gaaaaaaatg atcatgcaat gggagaaaga agaagtaaag
     3961 cctaagatat taatacatac atgctgtgct ccttgcagta cgcacacatt ggaattcatg
     4021 tctcaatatg cagagatcac gttatttttt tcaaattcga atattcatcc taaaagtgag
     4081 tatttgcgaa gattacatga acaaaaacga tttgtagacc aatttaatga gaaaactgac
     4141 catcatgttg cgctaatcgt tgatgaatac cgtccaaatg aattcaccaa aatggtttta
     4201 acaaaccatc ttgaaaacga aaaagaaggt ggtgctcgct gcagtgcatg cttcaatatg
     4261 cgattagatc ttgttgcgca aaaagcgcaa gaactaggat acgattactt tggaagtgcc
     4321 ctgaccatct cgccaaagaa aaatgcagct ttgatcaatc agatcggaat ggatatccaa
     4381 aagatttacg ggacacaata cttgccaagt gatttcaaga aaaacaaagg ctatgaacgc
     4441 tctttgcaaa tgtgcaaaga gtatgatatt tatcgccaat gttattgtgg ttgcgtgttc
     4501 gctgccaagc agcaaggatg cgatctgaaa gaaatcaatc gggaagcaaa agcttactta
     4561 aaaacatcaa ccgtagtttt tgaggaaaat taaagaaatc tttcggaaaa acgtaagaaa
     4621 aaaataaaga atttatggta gaaataaggt agactgtata atttgtccgt agtaaagtaa
     4681 ggaaacaaga ataaatttca atgaaggaag agataagatg cgaaaagtag cacctatttt
     4741 gaagccaatc gctgtattaa caatctcgac gattgtcgcg actactacag gtattgtgaa
     4801 tagttccagc taccgtgcac caagttcaag ttctagtact gtagaagaaa caacaccaac
     4861 tacttcagtc tcgacatctg aaccaacaac aacggaaagt ttgaatgaaa ccactacgac
     4921 aagtacatgg gacgatacaa caactagttc gtcgtatgat gagacatata caactgacag
     4981 ctcaagcgaa acaagtaata cggtaccaga tggcactcca tcggattcaa ccaatccaag
     5041 tacaagtccg gatacaagtg ctagctccga aacgatacca agcagtacga ctgtagatga
     5101 taacacgcaa aatgatgatg cagcacgtac agcacagcaa aaccaagatt caggaaatac
     5161 ccaaacgtat aaccagcaag caggtgattc tcaatgacat ttttactaga ccttatcaac
     5221 ggggtgcata aattccttgg ctatttagac atcagtccta aatatcttaa ccgtggatat
     5281 acgattttaa gtgtgattcc cacgctttat ttattgagaa ttgtttatgg actttggcaa
     5341 aaccaaaact atcttcaatt tttcttatat ggacttgcat ttctagtgct tgtttatttt
     5401 actgttttaa atgtatttta ttacttttta gataaaaaca cgaaagccga tgtcactcag
     5461 ctttttgtga agtatttacc tgatgaagcg ttcaacatcc agacagaaga atcgatagat
     5521 aatggaaatt cgatcgataa agtgaataca caagaggtca tggtttctta tgacgaagat
     5581 tatcaattga aattagccga gaatatgcgg tatttgattg gaaatggtga gatcaaaaca
     5641 aatgaactcg gtcgcatgga tggatttctg gtcgatagaa atacattgta tccttattac
     5701 tatgtcaaga aaacaggaga gaaagagtat gttctaaata ttggacgaag ctactcggac
     5761 atggaaaaag tagggaccat tcgacttgac tcaacagaag acacattgga acctgtcgga
     5821 ttgttcatcg tcggcggtga ttttgtcaaa gacgggttac gctatcatga gccttatcgt
     5881 ctgaaattga ttgcaaaaaa ggcacagtcg caggaagaac cagtggttta tagtcgtagc
     5941 caaagaagaa gacattcata atgtgatgaa acgccgtgta tcagtggttg cgataaaaac
     6001 gtttattcgg aataaggggg atgtgacacg tcttttgtca cgttcctttt ttatataacg
     6061 agaaagataa gacgaacaca tcacttattc tttcctttca tttataaaca ttgtagaata
     6121 aagaaagtac aacgaagtat tgtgaaaaaa cgtaataaat aacgaggaaa atacaagtag
     6181 gaggtaagct gtgaaagaat ttttgaaaaa ttgggggatt ttgatccttg tattagcggc
     6241 tattttatta gctagagtgt acgtgtttac accagttact gtaaacgggc attcgatgga
     6301 ccctacatta agtgatggac aacgattgat ttcatctaag atctcaaact atgaacgaat
     6361 ggatattatt actacaaagg aaccggggga tgaagaacgg atgattgtta aacggatcat
     6421 cggtatgcct ggagatacag tcaagatgga aaatgaccag ttgaccatta atggcaaaaa
     6481 gtatgatgaa ccttatctgg atgagttcaa aaaagaattt tcagaagata agttacaagg
     6541 agaatatgct tatagctcag gattccaagc acaagcagaa agttcatcca cctttacgag
     6601 tgactttgaa tatactgtgc caaaaggaaa gtatcttgtt ctaggcgata accgcttgat
     6661 ttcaaaagac agccgaatgt ttgggttagt cgacaaagat atgatccaag gaaaagttgt
     6721 tttccgttat tggcctcttt cagaaattaa aatcatgtga tgaaaaaata aaaagaagct
     6781 gtgacatgtt ttttgtcaca gcttcttttt ccgaaaattc cttcttattt cttggagttg
     6841 ctcacttttt ttgcaatctc attttaagct ttttggctga tggataagaa aagcgaagcg
     6901 tttttgttca taaatagctt ttccccacga tggaaggtat gactagtagc agagacaaag
     6961 cccgtttttt ccaatcgatt attcaattct tcttggctaa agccattatg gactttcgga
     7021 tgactaattt gttcattctt gtcaaagtct acgatgatca attgaccgcc aggagctaaa
     7081 atttcataaa gttttgtaag aatattctcc gtatcaggaa tgtgtaaaag tacaagtgat
     7141 agaaggatga gattagcttg gacagcagga aattcgacag aagcatcagc gtggatcgtt
     7201 cggacatttt tcagatctgc tgcttggatc ttttcttctg ccattttcag catagtttct
     7261 gaagcatcgg caatgatcag ttctttgaat ctttccgcaa gcggtaaact aacaagccca
     7321 gttccgcctc cgtaatccag caggactttt tggtggctgt cgcgcggtag ataagtagtt
     7381 agttcttcgc gaataatctt ggctaatgct tgacggtcag gggaatcata atggttagcg
     7441 atggaatcaa aaatattttt tgtcatcaaa tagctcctta cgtaaaactt tgaaatttta
     7501 acttattata gcacgtgaaa agaaagaaag catgctatac tcaattcaaa aagggagaat
     7561 ctagaaagaa tatgccgata tcgtttgtaa aagatagaga ggaaaaagga aagtgtgtcc
     7621 gagaaatatt actagacttg cctgagtggt ttgggcttcc tgaatcaacg gaaaaatata
     7681 tcgaggaatc aagtaaacta cctttatggt gtgaaaaaag aaaagaagaa tatttaggct
     7741 ttatcactct ttcacagaca agtgaagata ctgccgaaat ctattctatt gtatgggaat
     7801 aaaaaaagac tatcatcacc aaggattagg aacaaaactt tttaaagaag cagaaggtta
     7861 cgcagcaaaa cattacaaat atttgcaagt gaagactgta gacgaggggc actactctat
     7921 atatgatcaa actatttgtt tctacgaatc attaggattt tcaaggttgg aagtttttcc
     7981 aaatttatgg gatgaatgga acccatgttt agttcttgtc aaaaaattgg aacaaaagtg
     8041 agcaatagat ttaatactaa tctgtgcttg atgaaaattc tcactgtaaa aaatgctgaa
     8101 aatcaagtat aataccatag gaacaaactg gaaggtgaaa aagagcatgg cacaactatt
     8161 ttttaagtat ggcgcaatga atagcggcaa gacgatcgag atcctaaaag tcgcacataa
     8221 ttatgaagaa caaaataagc cagttgtctt aatgacaagc ggtattgata caagagatgg
     8281 tttaggcgtt gtttcaagcc gaatcggact gaaacgtaat gcgatgccga tatttgaaga
     8341 aacagacgta tttgacgtaa ttcagaaaat ggaaagcaaa ccctattgtg tgctgatcga
     8401 tgaagcgcaa ttcttaaaaa agaaacatgt cattgctttt acgagaattg tggacgaatt
     8461 ggatattccg gttatggcat ttggtttgaa aaatgatttt cgaaacgagt tatttgaagg
     8521 atcaaaatat ttattgcttt atgcagacaa aatcgaagaa atgaaaacaa tctgttggtt
     8581 ctgccacaaa aaagcaatca tgaatttaca ttatattgat ggaaaccctg tttatgaagg
     8641 cgatcaagtg caaattggcg gaaatgaagc ttattacccc gtttgtcgaa aacattactt
     8701 tcacccatca atgattacag aaggagaata agcatgtacg atcaattaca agcaattgaa
     8761 gaccgttatg aagagcttgg agaactttta agtgacccag aagtgatttc tgatacaaag
     8821 cgttttatgc agctttcaaa agaagaagca aacacgcgcg aaacagtcga agtttatcgt
     8881 cgttataaag aagtagtaca aggaatcacc gatacagaag aactgcttgg tgaaaaactg
     8941 gatgatgaaa tggctgaact agcaaaagaa gaattatctg aattaaaaaa agaaaaagaa
     9001 gtcttagaag aaaaaatcaa gatcttgctt ttaccaaaag atccaaatga cgataaaaat
     9061 atcatcatgg aaatccgtgg agcagcaggc ggagacgaag cagcattatt cgctggcgat
     9121 cttttcaata tgtaccaaaa gtatgctgaa gcacaaggct ggaaaacaga agtgatggaa
     9181 gctaacgtta ccggaatcgg tggatataaa gaagtgatca tgatgatcac cggagacaac
     9241 gtatattcga aattaaaata tgaaagtggt gcgcaccgcg tccagcgtgt tccttcaact
     9301 gaatcgcaag ggcgtatcca tacttccacc gcaacagttg tcgtgatgcc agaagctgaa
     9361 gaagtagaga tcgatattga agacaaagat atccgtacag atatctatca tgcttcaggt
     9421 gctggcggac agcacgtcaa taaaacagca tctgctgtac gtttgactca cttaccaaca
     9481 gggatcgttg ttgctatgca agatgaacgt tctcaaatca agaaccgtga aaaagcaatg
     9541 aaaatcttgc gtgctcgtgt gtacgataag atccagcaag aagcacaaag cgagtatgat
     9601 gccaatcgaa aatcagcagt cggaactggg gatcgttcag aacggatccg gacgtataat
     9661 ttcccgcaaa atcgtgtgac tgatcatcgt atcggattaa ctatccaaaa attagatcag
     9721 attttagcag ggaaattaga tgagatcgtt gatgcattga tcatgtatga tcaaacatca
     9781 aaactggaag ctatgcaaaa tgggtaaaat gacctatcga gaagtcctgt cacgggcttc
     9841 ttctttttta gaggatcatg ggaaagaagc atatagtatc caatttttat ttttggaacg
     9901 aaaacaatgg aaaaaacttg attggctcct tcatatgaac gaagagattt cagaagaaga
     9961 acagcggttg atcgaaaccg atctgcgact tctgcttgca gatcatccac ctcagtattt
    10021 gctaggatat gcagattttt atgatcatcg gttaaaggta actgaagcaa cactgatccc
    10081 tcgaccagaa acagaggagt tagtcgaatg gtgtttagac gagacgcctg gtgtaccgtt
    10141 agaagtgata gatattggga cagggactgg agcaattgct attagtttga aagcagcaag
    10201 aaaaaattgg catatatctg ctgtggatct ttcagaagaa gcattagaag tagcgaaaga
    10261 aaatgctcag aaagaaggaa cgaaaatcag tttttatcat ggagatacat taggaccagt
    10321 aatggatcag caatttgatg tgattatttc taatccgccg tacatcagtc ggaatgaatg
    10381 ggaactgatg gatgaaagtg tccggtcatt cgaacctaaa atggcccttt ttgctgagaa
    10441 cgatggatta gctatttatg aaaaaatagc agttgaagca ccaagcgtac taaaatcaaa
    10501 tggaaagatt tttttagaaa tcggatttcg ccaaggtgaa gcagtaaaaa aaatatttca
    10561 gcaagcattt ccagataaaa aagtggcgat aaaaaaggat ctttttggca atgaacgaat
    10621 gatccaagtt tatggttgaa gttgtggatg aaaaattttt tatttgtttt tttattataa
    10681 aaaaacactt atttgacaag gatgtaaacg actttttggt ttatcaacaa gtttatccac
    10741 tattgacaaa tagattatcc acaaacagtg gaaaacttga ggataaactc agacaaaata
    10801 agaatgtatg aaaaaggggt tgtggataaa ctgtggaaac gaaacgatat gatgaaacag
    10861 aattgcaaga ggcagccgaa gcactgaaag aaggagaact tgttgctttt cctaccgaaa
    10921 cagtatacgg attgggcgcc aacgctcttt taccaaacgc tgtcaagaaa gtgttttctg
    10981 taaaagggag accgcaagat aatccattaa tcgtccatgt cgcctctttt gaacaagtaa
    11041 aagagtatgt ggacaacttt catccggcag cagagaagat tgtgaagaac ttctggcctg
    11101 gaccattaac tttgatattt aagatcaaaa aagacacttt gccctcagtt gtgacgggag
    11161 gattatccac agctgcattt cgtataccgg ataacaaaaa aacactagaa gtaatcgaac
    11221 tttccggtgt tccgcttgtc ggtccaagtg caaatacgtc gggaaaacca agtccaacga
    11281 ctgcagatca tgtatatcat gatctacaag gaaaaattac cgggattatt gatgatggag
    11341 ctacgcgaat tggtgtagaa tccactgttc ttgatttaag tgatccaaca gccatgccta
    11401 tgattttacg accaggtgca gtaacgaaag aacaaatcga agcagtcatc gaatctcctg
    11461 ttgctattga tcagcatctt gtaaaagaaa atgaaacacc aaaagcccct gggatgaaat
    11521 acaaacacta ctcacccgat acacgtgttc tgatggtcag agatggcgat tggtcaactg
    11581 cagttcaatg ggcaaaaaat aagaagatcc gtgcaggtgt catagcaagc cccgaaattg
    11641 cggatcaagt gcggacagat actgcagctg tttatatgta taacgacaac tcagtagaag
    11701 cggcggctaa aggattgttt gcaggtctaa gaggattaga tgaaccaaca cttggattag
    11761 atttgatttt tgtacaagtg tatccagaaa ctggattggg gaatgcttac atgaatcgct
    11821 tgaaaaaagc agcaggacaa aattattttg aaaaatgatc aattggttat tgtcgcattc
    11881 ttttagtatg atacaatgct atcaagtaaa tcttctatca gtgaacgaaa aactaagcgt
    11941 aactaatcgt aatagaagag atacgaatat ttggcaattt gtttttgatg ggaaaaataa
    12001 aattgtagga aaataaaaag gagctgttgt ttgtggtaga ttacaaaacg tttgaccctg
    12061 atctttgggc tgcgatcgcc aaagaagaag aaagacaaga acataatttg gagctgattg
    12121 cctctgaaaa ctttgtctcc gaagcagtga tggctgcaca aggaagtatc ttgacaaata
    12181 aatacgcaga aggttatcca gggcatcgct attatggtgg gtgtgaattt gtcgatatcg
    12241 ttgaaaattt agcgattgac cgtgcaaaag aattattcgg agcgaaattt gcgaacgtcc
    12301 agcctcactc cggctctcaa gccaacacgg ctgcttatct cgctttggta gaaccagggg
    12361 acacgatctt aggaatggat ctttccgcag gcggacatct aacacatgga tcaccagtca
    12421 acttcagtgg caaaacctat cactttgttg cttacggtgt tgatccgaca acagaagtta
    12481 ttgattataa tgtggtacgt attttagcta gaaaacatca accaaaattg atcgtagcag
    12541 gtgccagtgc ttacggacga acgatcgact ttgcgaaatt cagagaaatc gcagatgaag
    12601 taggcgcaaa actgatggta gatatggcac atatcgcagg attagtagca gcaggacttc
    12661 atcctaatcc agttccttat gcagatatca caacgactac cactcataaa acattgcgtg
    12721 gccctcgagg cggcatgatt ttgacaaacg atgaagcatt agcaaaaaaa ataaatagtg
    12781 cggtatttcc tggtattcaa ggcggccctc tagagcatgt gattgcgggt aaagcagtag
    12841 cattcaaaga agcattagat cctgcattta aagaatatag tgaacaaatc atcgccaatg
    12901 caaaagcaat ggtcaaagtt ttcaatcaag caattggaac cagagtcatt tcaggggcga
    12961 cagataatca tctgatgttg atcgatgttc gcgagttagg tataaatgga aaagaagcag
    13021 agagcatttt ggacagtgtg aatatcactg taaataaaaa ctcgattcct tttgaaacac
    13081 taagtccatt caaaacaagc ggtattcgaa tcggcacgcc agcaatcact actcgcgggt
    13141 tcaaagaaga agatgctgta aaagtggctg aactagttgt caaagcatta caagcaaaag
    13201 atgataacgc tcaactagac gaagtcaaaa caggtgtacg cgaattaact gaaaaatttc
    13261 cgttgcataa aaaataaaaa tttaaattcc attagtaaac agaaaagttc aatgttgggc
    13321 ttttctgttt attttttggg aaaacggatt ctttgacaat atcggtgatg ctctctagta
    13381 tatgaggtgt aattttagtc ttcacactaa atctcaggga ggaaaagtca tgactgatcg
    13441 tatctcgtta gaaaaggaag cagtagcatt cagtgatgca aatgcgcctc atccgcgtat
    13501 ctatgaacta gcaccggaag aaggaagagt tttactagaa gaagtacaag aatcacctgt
    13561 gaacaaatat tccgtcgata ttgaagactt gatggtggat actggcgaat ggggaaaact
    13621 caatattcgt ctcgtacgac cagaagggaa tatggataaa ttaccagtta ttttttatat
    13681 tcatggagca ggctgggttt ttggcagtgc tcaaacccat gataaattga tcagagaact
    13741 tgcggttcgt acgaattccg tcgttgtctt tccagaatat agtcgatcac cagaagcaaa
    13801 atatccaaca gcaattgaac aaaattatgc tgtgttgcaa cagctgaata aattagccaa
    13861 gtcaaaaaat ctggatctcg agaatctaat cgttgcagga gattcagtag gtggtaacat
    13921 ggctacagtc atgacgatct taacaaaaga acgaaagggc ctcccaatat ccaagcaatt
    13981 gctgtattat ccagtcacaa acgctgattt tgatacagat tcctatcatg aattcggaga
    14041 aaactatttt ttgacaagag aaggaatgat gtggttttgg gaccaatata cgacgaatga
    14101 agaagagcgt gctgaaatca cagcttcgcc tttgagagca aatataaatg aactaaatga
    14161 tcttccttca gcaatgattt taacgggaga agcggatgta ttaagagatg aaggtgaggc
    14221 ttatgcgcgc aaacttcgtg atgcaggggt tcctgttaca caagtacgct tccaaggaat
    14281 catccatgat tttgtcatgg taaatgctat ggatcagaca aaggcaacgc gtgcagcaat
    14341 ggcattatct acttcttgga tcaagaaaaa agaataagct ttgcttgtcc gcaggaaaac
    14401 ttcttttcaa aaacggattt tcttaggaaa aatggcgagt ttgactagtc aatcacttga
    14461 ttttgtttta caattaaaaa gaaacgacag aacaaaggag agcttaaaaa atgggcaaat
    14521 ttcaagtgat cgatcatcca ttgattcaac acaaactaac tattattcgg gacaaaaact
    14581 gcggaacaaa ggtttttcgt gaagtagtcg atgaaatcgc tatgttgatg gcatatgaag
    14641 tatcacggga tatgccattg gaagacatcg tgatcgaaac accgatcact gaaacaacac
    14701 aaaaaacgtt gtctggtaaa aaagtagcga ttattccaat cttgcgcgca ggtattggaa
    14761 tggttgacgg tatcttggaa ttgattccag ctgctaaagt gggacatatc ggtctttatc
    14821 gagatgaaga aacattggaa ccacatgaat atttcgtcaa acttccagaa gacattgatg
    14881 cacgtcagtt gtttgtagta gatccaatgt tggcaacagg cggatcagca atcatggcaa
    14941 tcgatgcatt gaaagaacgt ggcgcgtcga acattaaatt tgtttgtttg gtagcagcac
    15001 ctgagggagt aaaagctttg caagaagcgc atcctgatat tgacatctat acagcttctc
    15061 tagatgaaaa attgaatgaa catggttata tcgttcctgg actaggggat gcgggtgacc
    15121 gtttgtttgg tacaaaataa gtaaatacga aaaagggtgt gacacaactt ttgtcacatc
    15181 cttttttggt catttttaac gtttgatgca gaacagcttt ttcacagctt tcgtttgcat
    15241 ataaaaaaac catcccaaaa atgcagagat ggtcaaattc aaatcttttt tagttctttg
    15301 tagttaacga ttactacacc cttactttgc gtcatcaagt tcgcattttc tgcagtttca
    15361 tcaatctcaa caacagcgga atttttcaat tgctttgaaa tcgttccagt ttgcgacttg
    15421 ccgtgaattg tgaacattac gtgagtattg atcttgaatt tttcaccaat ttccgatggt
    15481 acgatagttg tatcaaattt tccaaaagtt gccattttca taaaacctgc ctttcacatc
    15541 aattatacca cgttttatga aaaatatcat gaaattaaac taattttcca tcggactctt
    15601 tacaatcagc caaatagagt atataatttc ttttggataa ggccagctta gctcagttgg
    15661 tagagcaacg cactcgtaac gcgtaggtcg taggttcgat ccctatagct ggcattaaaa
    15721 gagaagacag atatatcaag gatttttaat ccattgatac atctgtcttt ttgtttaaag
    15781 gaaataaagt atgctttctt agcaatagag catgtattat ttctataaaa atttaggaga
    15841 ataaaacgac tagcaatata gctgtgaaat caaatatcac atgaactgcc caacttgtaa
    15901 tgatcgagtt gcttttaatg gcagcttggt tgaataacaa tcttgccacc ccttgtatca
    15961 aaaggatgtg tgctacagtg tgtaaaatat ttccattatc ataagtactg taatggataa
    16021 atccaaagat gattgctgac aagaaactag cgacaggaat gctgaactta ctagaaaaaa
    16081 tagcgagaaa atacactgag aacaattctt ctccaagtat catgataggc aaaataataa
    16141 ataataacgg gctgaaagcc tcatttattg gattgcctgt taaaccccat ttcaaaattt
    16201 gttgcaaaaa taccgagact gcggcactga ttactacatt gataaaaaaa tatttggcta
    16261 tatttttgac aggagcgaca ggtttcgaga acattttttt cgtatctttt ttaccaaaaa
    16321 caagtgtaaa tgctataaat ccagtgatag ttaaagaaaa aatgctaata atggatggcg
    16381 caaatagcaa ccctaacaaa ccgagtacaa cgacaatagt gcccaatatc ccttttttaa
    16441 gttctatttt ttttcctaaa atgttattca tgataataac tcctactatt cagtttttga
    16501 agatagagtc agtatacatg aagagttaaa ataggcaatg tttttttatg gatatttgta
    16561 ttgctaaaaa tttatcttat atattcattt tgattatact acttttattt gtaaaaattt
    16621 tctagcaaaa ccaagtgctt gcaactgatt aagcgtacaa ttttttagat gttccgagcg
    16681 tacttcaatc atttcaaagg agttgctact taaatcgata ttttttaaat cagtatcaaa
    16741 aaagctagca ttttctaaat cattagtaga aaacattatt ttagtgaggg aacagtctac
    16801 aaaatctgcg cttgataaga cagagtgctc aaaggtactt tcttttatgt ttgaaccaga
    16861 taaatttaca tagtccattt tacaattctc gaataacgtg ttcccaatat aactttccat
    16921 caatttagta cctgttaatt tacaattgac aaatttcacg cgatgcaaca tgctttttgt
    16981 caatatacag cctgaaaaat cacagttttc gaatatacag tcggtaatct ccattctttg
    17041 aaaatcattg gaagcaaaaa atgcatactt gaaaatagat ttgtaaataa ttggatggca
    17101 gattatttgg ttttcgatga cctctttttg tgaaaggata ttatacagtt caaaatcttc
    17161 gttttcatag atatgaaaaa aggatccttt attcaagctt gcttcattaa ctttaggaaa
    17221 aatcatattt aattacctcc attttcataa agtcatatta acaaaagcta aaccaactta
    17281 cattagcaga aaatgagata ggttttcgcc tttttcgata acgatagtgt cgctatctct
    17341 tgaaacgttc ttagaattgc cctgagagac acaaattagg cgtaattcta ataaaaatct
    17401 tagaataaaa atttttactg atttaattta gaatgttttt aaaataaaaa tcgttgccat
    17461 aacagtgtat tgaaaggttt taacaatcca gtaatgattt aaaaaaatct agatgtagcg
    17521 tatactttgt ttatagaatg tagtgggaag aaatatattt ttgggaggaa atcgtgatgt
    17581 ctaaaagtga agaaatagaa aacatggtac taaaattata tgatctcgtt ttaaatccag
    17641 agatcaaaga aaaggaacgt atacttttga tagacgcaaa gacaggctta gaaaaaggtc
    17701 agtattatcc taaagtcata aataatttgg aacgtagttt acgtccgtta gcaatcaggg
    17761 gagaattgtc taaaccagta tcaccgtttt atatggagat atcaacaata ggaaaatttg
    17821 aaaaagaatt aggtcgagga atggcttcgg caccgattac ttttgggcat ttataaaaac
    17881 gagttattca tctcaatgaa ttaaaaagta tagtcaatct cataatgcag gctaggttca
    17941 tttatttgaa cagagtctgt atttttttat tctaaataaa gaaacagatg tttctttata
    18001 ttgtatttta tcctttaatt aacacaaaaa cagctagtat aaactaataa tgttaa
//
LOCUS       DAXLPC010000055        18001 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.055, whole genome shotgun sequence.
ACCESSION   DAXLPC010000055 DAXLPC010000000
VERSION     DAXLPC010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.055"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            126..1865
                     /gene="yfcC"
                     /locus_tag="ACF3UE_001789"
     CDS             126..1865
                     /gene="yfcC"
                     /locus_tag="ACF3UE_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFD3635185.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2022..3206
                     /gene="iadA"
                     /locus_tag="ACF3UE_001790"
     CDS             2022..3206
                     /gene="iadA"
                     /locus_tag="ACF3UE_001790"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFD3635186.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3317..3520
                     /locus_tag="ACF3UE_001791"
     CDS             3317..3520
                     /locus_tag="ACF3UE_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFD3635187.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3621..4283)
                     /locus_tag="ACF3UE_001792"
     CDS             complement(3621..4283)
                     /locus_tag="ACF3UE_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635188.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4296..5798)
                     /locus_tag="ACF3UE_001793"
     CDS             complement(4296..5798)
                     /locus_tag="ACF3UE_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3635189.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVTVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6346..8025
                     /locus_tag="ACF3UE_001794"
     CDS             6346..8025
                     /locus_tag="ACF3UE_001794"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFD3635190.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8152..8631
                     /locus_tag="ACF3UE_001795"
     CDS             8152..8631
                     /locus_tag="ACF3UE_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFD3635191.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8850..9530
                     /locus_tag="ACF3UE_001796"
     CDS             8850..9530
                     /locus_tag="ACF3UE_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFD3635192.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9538..10869
                     /locus_tag="ACF3UE_001797"
     CDS             9538..10869
                     /locus_tag="ACF3UE_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFD3635193.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10884..11846
                     /locus_tag="ACF3UE_001798"
     CDS             10884..11846
                     /locus_tag="ACF3UE_001798"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFD3635194.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            11957..12295
                     /locus_tag="ACF3UE_001799"
     CDS             11957..12295
                     /locus_tag="ACF3UE_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFD3635195.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12374..13081
                     /locus_tag="ACF3UE_001800"
     CDS             12374..13081
                     /locus_tag="ACF3UE_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFD3635196.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(13184..14665)
                     /locus_tag="ACF3UE_001801"
     CDS             complement(13184..14665)
                     /locus_tag="ACF3UE_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635197.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            14974..15510
                     /locus_tag="ACF3UE_001802"
     CDS             14974..15510
                     /locus_tag="ACF3UE_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3635198.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            15588..16958
                     /locus_tag="ACF3UE_001803"
     CDS             15588..16958
                     /locus_tag="ACF3UE_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFD3635199.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            17025..17360
                     /locus_tag="ACF3UE_001804"
     CDS             17025..17360
                     /locus_tag="ACF3UE_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635200.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(17441..>18001)
                     /locus_tag="ACF3UE_001805"
     CDS             complement(17441..>18001)
                     /locus_tag="ACF3UE_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635201.1"
                     /translation="QDTILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLS
                     LDADFDTTTSVFVGSFHSPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYY
                     TKDTVKDSKLIKSYIELIKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKF
                     QEQSGFNLKKANDLLFCYLLLLHEHN"
BASE COUNT         5798 a         3032 c         3839 g         5332 t
ORIGIN      
        1 aaaatagaaa aaagtgattt tctaataaat tattcatgtg gaaatgtcat ttttactgta
       61 taattcattt gattatccat tttttattca tcaaaattac tgaaaaaaga aaggaagaaa
      121 taaatttgaa gaaaacaaat tcttcaggaa aaccgaaacg cgacttcact aaattatcga
      181 caccccatac gtatgtcatt atttttggtg tagtcatctt tgcatggata ctgacttttg
      241 tcgttccagc aggaaagttc agcacgcaag atattgaata caaagatgca aatggcgaaa
      301 caagtactcg tactgtttta cgtcaagatt ccttccgtta tgcttacgag ctggataagt
      361 cgtatgtgtt tgatcaatta gaagaactgc aagatcatcc agcagaacgt gaaaaactgg
      421 atgttccgga aaaaggattg gaaaaagtca ttgctgacgg agaaaaaaat cttacgcagg
      481 aaaaactaga tgaaatctcc ttgacagatg atgtgcttta cgatcagtac ggcgaaaata
      541 tctatgatac ttctaaaaaa ttgcataaaa cagccaaaat atggggaaca gatgattttg
      601 gcggctttgg tttcttaaat tttgtttttg aaggactagt atctggagat aagtatggat
      661 ctgctgtagg gatcgctgca ttgatccttg ttgttggagg tgcttttggt attattatgc
      721 gtaccggagc gatcgacgca ggtatctatg cgtttatcag taaaactaag ggactggagc
      781 gtttagcttt accgctatta ttctttgctt tttcattcgg tggcgctaca ttcgggatgg
      841 cagaagaggt aattccattc tcaatggtga tggttccatt tgtcattgcg ttaggatatg
      901 actcgatcgt agcagtaacc gtgacttatg tcgcatctca agtcggaaat gcgacctctt
      961 ggatgagccc gtttagcgta gcggtggctc aagggattgc tggaatcccc gtgttgtctg
     1021 gtgcgacatt ccgattgatt atgtgggtag ttgttactgc attagccgct ggttatatga
     1081 tgatatatgc agaaaaaatc cgtaaaaaac cagaaagttc gttgacttac aaatcagatg
     1141 attatttccg ttctcatatc aaaaagacat ctgatgaaaa taaaaaattc atgcttgggc
     1201 ataaattgat cttattagag atgttagttg tccttgtctg gatcgtttgg ggcgtgactc
     1261 aaaaaggcta ttacattcca gaaatcgctt ctcaattctt tgtgatggga ttagttgctg
     1321 gaatcattgc tgttcttttc aaattagatg gaatgaaagt caatgacatc gcttcttctt
     1381 tccaatctgg tgcagctgat ttagctggta cagcaatcgt agtaggtatg gccaaaggga
     1441 ttcttcttgt cttgggagga tctgatgcat ctgttccttc agctttgaat acgattttgc
     1501 atgggatcgg gacggcgttg accggtgttc cagctgtcat tggtgcttgg gcgatgtaca
     1561 tcttccaaag tttgttcaac ttggttgtta catcaaattc aggacaagca gctttgacta
     1621 tgccaatcat ggctccactg gcagatttag taggtgtatc cagacaagta gcagttcttg
     1681 cttatcagct tggttcaggt tttatggacg cttttacacc cgtatcagcc agcttgattg
     1741 gtgtgctagg tgttgcacgg atcgaatggg caaaatgggc aagattccaa atcaagatgc
     1801 aaggattcct gtttgtttta ggaactattt tcatcatgat tgccattgca ataggtctgc
     1861 agtagtactg gagacctgta aataaaaaag taatccaaac agtagataag gactccaaga
     1921 accgtcattt tacggtaaaa tcaaaggagt aaagatccta tcgtttggat tattttttaa
     1981 gatcctatca tcagttatac ttaaagaaag aggaaaaatg tatgaaaatc attcgacaaa
     2041 ttgaagtgtt tgcaccagat tacttaggaa aaatggatgt actgattgcc ggtgggaaga
     2101 ttttggctgt agaagaacag ctagaaggcg gctacgaagg agtggaagta gaagaacttt
     2161 caggtgaggg aaaagtacta accccgggtt tcattgactg tcatttccat attttaggtg
     2221 gaggaggaga aggcggttat caaaatcgaa cgccagaagt cacattgagc caattgacta
     2281 cagctggtgt aacgacagtt gtcggttgtt tgggaacaga cggagaaggt agagatatga
     2341 ctgcgttgat cagcaaagcg aaaggtctgg aagcagaagg aatctccact tatgtatacg
     2401 aaggttcgta ccgattgccg gtaaaaacag taacagattc tatcatcaaa gactttttga
     2461 caattgataa aattatcgga atcggagaaa tcgcagtatc cgatcaccgt tcttctcagc
     2521 caagttttga agagttcgct cgtgcagtag cagatgctcg tgtaggaggc atgttatccg
     2581 gaaaagctgg gatcatcaat gtccacttag gcggaggaaa aagaaagcta gagctattga
     2641 cacgaatcgt agaagaaaca gaaattccga tcacacaatt tttgcctact catgcaaatc
     2701 gcacaccaga attatttgaa gcttgcgtgg catttgccaa acgtggtggc acgattgact
     2761 tcactgctag cgaagatcct gatttttggg agaagacaga tggtgaagtt cgcttcagca
     2821 aagcactgaa acgattgatc gaggaagatg tttctttaga taatttcacg atgacctcag
     2881 atggacaagg aagcttgcct tattttgatg aaaacaatca tttcctaggg ttaggagtag
     2941 gaagtgccaa ggcattgcta gtagggatca aagaagctgt gcaaaaagaa agtatccctt
     3001 tggaaatcgc cttacgagct ataaccagta atccagcacg tatattgaaa ttggataaaa
     3061 aaggaaaaat cgaaattggt gctgatgcag atctgtgtat cttggataaa gaaacgcttg
     3121 atattgatac agttatcgct aaaggagaaa taatggtcca agaaaaagaa gtcaaagtat
     3181 gggggacttt cgaaaaaagt ttttaatcaa cagctctaac tatctttttt agaaaacgag
     3241 cgttctgttt gtctgtatct gttgttgatg ttaccctgaa ggtagatcaa taaacaaact
     3301 aagaggagga agcacaatgg cagatttaaa aggacgttct aaagatatga aagataaagt
     3361 agtcggtgaa ggaaaagaag catacggcaa agcaacagac gacaagagca aagaaacaga
     3421 agggaaagca caatcactag gtgctgacat caaagaaaaa gctcgaaatt taggcgacga
     3481 agtcaaagac aagttttctc gaaaagacga aaaaaaataa aaaccactta ttactaattg
     3541 aatcaagcaa ataaaaaatc cgaaccatat ctgcgagaca gatatggttc ggatttttta
     3601 tttgatcatt atcctgtttt ttaaacttcg attttttgaa attttttatt ttttagttca
     3661 aagacttcat cacagctttt tgctacttca atctcatgag tcacgatgat aatacagcga
     3721 ttttgttcat gggcgatttc ttggaaaagt ttgacgatat cttgtgaagt tgtttcatct
     3781 agatttccag taggctcatc cgctacgatt agttgatgtt cacagcagat agcacgaacg
     3841 atagcgactc gctgctgctg acctcccgaa agtttggtca cctgtttttt tgctaatatt
     3901 tcatcaattc ctacacgagc cagtcgatct aaagcaactt gtcgataatt ctcttgcttg
     3961 gtcttagtga tttccattgc tgctatgacg ttgtctagag ccgataaata aggaagcaag
     4021 ttgtaagctt ggaaaataat cgagacatca tttttacgat aacttcttaa cccgattttg
     4081 ttcagtgaac gatcttgata gtataccttt ccttcttttg gtgcatctag tccagaaata
     4141 agcgaaagaa aagtcgtttt tccagaacca cttgctccta aaatagcgta catttttcca
     4201 gcttcgaaat tcagttctac atctttataa agcgcatctt gcggatcttg ataccaaaat
     4261 cccaattgtt ctgtccgtaa catcaaattc ctcctttagt ttaataggat ttttcttggg
     4321 tttaatctta atatccctat agaagctaaa aagacagaaa acagactgat tccaaatgct
     4381 actccggcta atagtcccaa ttgtgcaggt ttgacattga tttccaattc gctgacttga
     4441 tcagaaacag caaatggatt attcgtggtt ccttgttgac catcgcgttg accgccttgt
     4501 tcttgtctgt tacctggcat ttgtccaccg ccaggagctt gctggttttg tgtcgtggtt
     4561 tctgtctgtt ggtcaagtag ctgctgtccc acggcattcg cgacgacgtt tccgctaagc
     4621 gaagcaactc ctaatgcaag aatcatacaa atagccactt cggtaaacaa ttggagaatg
     4681 attttacttc tggattctcc taaagatagc aagacgccta actcatgccg acgctcccga
     4741 atggtaatca taatgatcag agtaagtatg ataataccgg ctacagtcac tagtaaaaca
     4801 acatttttag aaaaacttgc cacgttgttt aaaggttcca acattgactg atacatggaa
     4861 tcatttgatt gtaagctaaa tgtatctgtg tcgatcagct tctcagcttc tttgagaaac
     4921 tcatccattt tatctggatc agatagagtg taaatagcag aatctatcgt gttatcgtca
     4981 gatgtcccat ttagttcatt tgcaaaagtg taagaagtgt aaagtgtatt cgacggattc
     5041 atgaagttga atttcatacc catactgccg cttgtttcgc tggattcata aattcctttg
     5101 atcgtcattt cataagtggt atcttcatct tcagtactcg tgattgtgaa agtatctccg
     5161 actgccaggt catttgtttc tgctagagta gaatcaatga ctacattgtt tgtgcctttg
     5221 tcgctgtcat ctattccttc accatccgtg atttttgctg ttccatcaga aaaattacta
     5281 ttttgtgcag ttgctgacac accactgatt tgaaagtctg cttgagtcat ttgcggattc
     5341 ccgcccattc ctccagcagg ttcaccgcct gcatcagtag tttctgaact gtcttcactt
     5401 gaatcagaac tagtgatggc agttattcca tcttttgcca tagctgaggc ggaactttca
     5461 aaggaataac tctttacatt atctaattca gctatttttt ccgcgtccgt taaggaaact
     5521 ggtgtaagag aaaaactgcc tggatctgga cgttcttcag tggtagaacc gcttgaagaa
     5581 gtttgttcct gttttttaaa tgaagcttct cgattggcac ttaaagtcac tgttgctcca
     5641 acttcttttt gtgcttgatt cgctgcttct tctgcagcgc ttcgaatcgt gaggccagct
     5701 agcacaaaaa taagaatggc tgtgaacacg gcaaacaata acaatgaacg tccccatttt
     5761 acttttgtac ttttccatgc acgtttcata aaattcatat tttgcatccc tcctagtaga
     5821 tgcatttgat aatagacaac ctatcttaaa gctagcttaa atcttatgct gtttgcacac
     5881 catcaacatg aggttctgta tatataaaaa gtcactatag ttattgcaaa aaatgtggta
     5941 aaatgaaaaa agtatgtttc aaaccgacga agaagaaatg aaagaggaat agcaaaagaa
     6001 atcctagatg ctacagaggg atttttacgt gcatagttgt tctaacaatt gctgatacta
     6061 gcgatttagt ttatttgttg tataataatg gggaacagct gaatacttat ataagtattc
     6121 tggctatagc gtttcgcaaa agatccattt tgttaatgaa gtatatccaa aataaaatgc
     6181 ccatccaact gtcagaacgc ggatgtgctg gtaattttcc tgctgattct ccataagttg
     6241 agaaatagtg attttgcata tgcttcattg gaatggctca tatatttaga taaagaagaa
     6301 aatcgacatc tttaaacttg gatgtcataa gaagaggtga agtttgtgag taccattaaa
     6361 attatcccat taggcggcgt tcgtgaaaat ggaaaaaaca tgtatgtcgc agaagtgggc
     6421 gaggatattt ttattttaga ttgtgggcta aaatatcctg aaaatgagtt gttggggatc
     6481 gacgtcgtaa tccctgattt tacgtattta gaagaaaaca ttgatcgtgt agctggtgtc
     6541 tttttaacac atggacatgc agatgcgatc ggggcacttc cttacttgtt gtcaaaaatt
     6601 tctgtaccag tattcgggac agagttgacg atcgagttag caaaattgaa tgtcagtcgt
     6661 aatgaagcag ccaaaggatt taaggatttc catgtggtag atgagcatac agaaatagac
     6721 tttggtgaaa cagtagtgag ctttttccgt accactcata cgataccaga ttcagtgggg
     6781 atcaatctga aaacaaaaga aggtagtatc gtttatacgg gagattttaa atttgaccaa
     6841 acggctatcc caatgtatca aacagattat gcacgattgg cggaaatcgg caaagaagga
     6901 gtcttagcct tactaagtga atcggcaaat gcagaaaatc ctcagcctgt agcttctgaa
     6961 gcccaaatag cagatgaagt atttgatacg atcaaatatt gggaagggcg tatcatcgtc
     7021 gcttgtgtag caagtaattt gcaacgagtg caacaagtat tggatgcagc agaaaaagca
     7081 caacgaaaag ttgtcttgac tggtcaagat ttcgaacgaa ttattcgcac agcgatgcgt
     7141 ttagaaaaac ttcaattacc aagtgaagat ctgcttgtta cgttgaaaga catgaaaaac
     7201 tatgatccag aagaactgat cattttagaa actggccgaa tgggtgaacc catcaagtct
     7261 ctgcaaaaaa tggcaaacgg tacacaccgt aatgtcaaga ttgaagaagg agatttggtt
     7321 tatatcacta ctacgccaag catcgcgatg gaaaccatcg tggcgaaaac ggaagatatc
     7381 atttatcgag ctggtggaac agtgaagttg atctctgaga atatgcgcgt ttctggccat
     7441 gccaatccta atgacttgca attaatgatc aatttgatga aaccaacata ttttgtgcca
     7501 gttcaaggag agtatcgtga attagctgct catgcagatt tggctcatgc agtagggatg
     7561 ccatacaaaa atatctatat tactggacgc ggagacgtgc tggaatataa gaacaagcgt
     7621 atgagtgttg caggaactac aagtgcagaa aatgtaatga ttgatggatt aggcataggt
     7681 gatatcggaa acattgtttt acgtgatcga aaaatcttgt cagaagacgg gattttcgta
     7741 gcggttgtca ctatcagtcg gcgagaaaag aaaatcattt caaaacctca aattacttca
     7801 cggggattcg tttacgtaaa agctagccgt gatctgatga aagaaagcag caatatgatt
     7861 gaaacaatcg ttgagaaaca tttagaaagc aatgattttg agtggagcaa attaaagcaa
     7921 gacatccgag atcaattagg ccgttactta tttgaacaaa caaaacgccg cccagtgatc
     7981 ttgccagtca ttatggaagc tactcaacgt cgaaataaaa aataaacaaa aagagtaaga
     8041 tgaacctctc tatagagtgc tcgtcttgct ctttttttgc gaaaaacaaa taatttttga
     8101 atacagcatc cctcgcttta taataaacga tagaataaag ggagtgaatc aatgatgagt
     8161 caaacaaaag tcgaacgtta tttagaagaa caaaagatca gctatcaacc acttgatttt
     8221 agtcatgtgg tagaagaatc tttcacagaa gaactacaaa aaagagggat tgatccagct
     8281 ttgatatgta aaactctcgt agtgaaagga aacaaaactg gggtgatcat cgcattgatt
     8341 cctttgaacg atcacttaga ttacaaaaaa acgagacaag tgacgaaaga tcgtaaagtt
     8401 ggttttcctg gaatggattt tgtattaatg catacaggat atccccacgg agcaaacacc
     8461 cctattggaa taaaactcgc acatcctgat tattgttttt tagcagacag ttctttaaaa
     8521 gaaaaagaag aagtaattgt gtcaagcggt gaaatcggga gaagccttcg gataaaagta
     8581 gccgatttag aaaagatcgt ccatcctatt tacgctgatt taattagtta agggacgaga
     8641 agagaagcta agcagagcag agacctcaaa cttgagatta tatctgcttg gtacttggtg
     8701 catcctgtat tatctgttac aattgctttg tacatactgt actatcaatc caatgaaaat
     8761 atatttagca gctatatttt ttcattgatg tgcaagtgat gaaatcgttt ttaataaaaa
     8821 agatacagag aaaacgcgag gtgtaaaata tgaaaattac gtatcatgga cattcctgtt
     8881 taacaattga aatggaaaat ggccaacgcg tgatgattga cccgtttatt acaggaaatc
     8941 cattgacaga cttaactgca gaagaagtaa agacagattg gttgctgatt actcatggtc
     9001 atagtgacca cataggagat atgattccta ttgcaaaaga aaatcaagcc acaattatca
     9061 gtattgttga gattgctgat tatgcgaaca gcagaggagt agattcattc ggtatgaata
     9121 tcggtggaaa acatgcgttt ccattcggcg tggtaaaatt cgtacatgca cagcatagtt
     9181 caagctatga agtagacggt atcgttcagt atatgggcga gcctagcgga attattattc
     9241 aagcagaagg aaaaacgatt tatcatgcag gggatactgc ttatttcagt gatctaggat
     9301 tgcttgcaga agaattcgat attgatgtcg ctttcttgcc gattggcgat aactatacga
     9361 tggggccaga agatgcagca aaggctgcgc aaacaattcg tgccaagaaa gtagttccaa
     9421 tccattacaa tactttccct gtcattgaac aagatcccga atcttttgta gagttactgg
     9481 aagatagtga aggaaaaata atgagcgtct cggaaacgct ggaagtgtag gcagaaaatg
     9541 gcgacaaaac atgatttgat tttagaatat attgaaagtt tacctgttgg caatcgaatt
     9601 tctgtaagaa gcatcgcaaa agaattgaat gtcagtgaag gaacagcgta ccgtgcaatc
     9661 aaagatgcag aaaatgtcgg actagtttca acaattcaac gagtagggac catccgtatc
     9721 gaacgcaaat taaaaaaaca tattgaacgt ttgacatttg gcgaggtcgt caggatcatt
     9781 gaaggggacg ttttaggcgg ggcggcagga ttagacaagg tcttgaataa attcgtcatc
     9841 ggcgcgatga ctaaacatgc catggaacgc tatattacgc caggatcact aatgatcgtc
     9901 ggcaaccggg cggaagtcca aaaattagca ttggaagatg gcgccgcagt attgatcaca
     9961 ggaggattca atacgactgc tgagattgca aagctagctg atgatcttga aatgccgatc
    10021 ttacgcacct cttatgatac atttacagtc gcaaccatga tcaaccgagc gttaagcgac
    10081 caattgatca aaaaagatat catgcttgtc agtgatatct atatgccagc tgaaaagact
    10141 cattatttgc agcagacaga tacgatttct gattatcagc gtttgtcaga agaaacgcag
    10201 cattcgcgtt ttccagtcgt caaccgccat catcgtttga tggggattgt tacggcaaaa
    10261 gatgttttag ggaaatcgcc aaaccagatc atcgatcggg tgatgacgaa agaaccaatc
    10321 agtgtaaaga aaacaatgag tattgcctct gttagccatc aaatgatctg ggatgggcta
    10381 gaagtcatgc cggtcgtttc cgatgacttg acattggaag gcttgattac ccggcaagat
    10441 gtaatgaaag cgatgcagct tgtccagcga caaccgcaga ttgcagatac gatttcggat
    10501 cagatatctg gaaatatcca tacgattgat actgaccgtg aaggaaatcg tttggaaaac
    10561 cctaagttca aattcgtagt agcaccacaa atggtcaatg gcgttggaac catttctttt
    10621 ggcgtactta gcgaaatcat ttctgatgtc gcacaaaaaa caatggtgat gaaccaaaaa
    10681 cgaaatatct tgattgaaca agtgaaccta cattatttgc ggctgatcca attggaaagc
    10741 gaattagaca ttcgtccacg tgtattggaa atcggcagac gttccgctaa actggatatc
    10801 gaagtgttta ttgaaaacac catcgtttcc aaagcaatcg ttgtttgtca agtaatggaa
    10861 cgttcttaga aagcaggagt gaaatgacag tacagcaaga aatagtagat acaataaaaa
    10921 aatacgataa aatcattatc cacaggcatt tgcgccctga tcctgatgca ttaggatcac
    10981 aagtaggatt agccgaacta ttacgggaaa gtttcccaga aaaagaaata cgtcaagtag
    11041 gtgaaacgat tgaagggctt cgctttttag cagaaatgca agaagttgaa gatgtcttct
    11101 accaaggagc gctagtcatc gtgactgata cagctaattc acccagaatc agtgatcaaa
    11161 gatatcagtt ggcagaaaaa ctgatcaaaa tcgaccatca tcccaatgat gacccttatg
    11221 gagatcttgt gtgggtaaat acaaaagcaa gtagctgtag tgagatgatt gcagaatttg
    11281 ctttgatgtt tcctgaatct ttaaagatga acgttaaggc tgcacggtta ctttatgcag
    11341 gaatcgtcgg agatacaggg cgctttttgt atccctccac gacgtcccgt acattagaga
    11401 ttgcttcgat attgagaaat tatccatttg atgcaagtgc tttgaacaga gagattgaac
    11461 aaatgccgat gaaagtcgct aaactttccg gttatcttta tcaaaatatc caggtggatg
    11521 aaaatggtgc aggaagaata atccttccgc aagaaattct tgataaatat ggaatcgatg
    11581 attcagagac agcttcgatc gtttcacttc ctggagtgat tgacgaagtg ctggcttggg
    11641 ggatttttgt tcagcagcct tcagggtatt accgcgtacg tttacgttct aaggggccga
    11701 tcatcaatga attggctaaa cgccatcatg gaggaggcca tccattagca agtggtgcga
    11761 atgcaaaaga tttagcagaa gtagaggaaa tctataaaga gatccaagat atatgccaat
    11821 cgtataagag cagaaaaaca gaatgatact tcgttcgaaa acgtgccttt tgtagtaaaa
    11881 atcacaaatg tatcttttca agatcttctt tttccgttac aatagtgctc actaaagatt
    11941 ttaaaggaga aagaagatga cattaccaaa ttgcccagaa tgtggctcag agtacacata
    12001 tgaagatcga ggcttgttga tttgcccaga atgcgggaac gaatggaaca aagaagaaca
    12061 agaaactgtc atagaagacg gattagtggt attagatgca aatggaaacc gtctgttaga
    12121 gggcgatagc gtgacagtga ttaaagactt gaaagtaaaa ggtgcgtcag gtgccattaa
    12181 acaaggaaca aaagtcaaga acatccgttt agtagaaggc gatcataata tcgattgcaa
    12241 ggtagaagga tttggaccga tgaaactgaa atcggaattt gtgaaaaaga attaaagaat
    12301 attcaaggtc ttttcacatt cttttcctac tactaatgat aaaataaagt aaacgaaaag
    12361 gagtgaaacg aaaatgtatg gttatggaat gtatggtttt ttagatccga catttctttt
    12421 ggtcattctt ggattagtta tttccggaat tgcgtcagcg tacgtcaata gtactttccg
    12481 aaaatacgat caagtgagaa gcaaaaacaa tgtgactggt acacaagcag cacaatatat
    12541 attacaaagt caacagataa ataatgtcgg tgttcaacaa attgccggag atctcacaga
    12601 taactacaat tcaggtaata agatgttgag tttgtctcaa gcaactgcac agtctacttc
    12661 agttgctgcg ataggtgtag cagctcatga atgcggacat gcggtacaag atgcttcggg
    12721 ttatgtccca ttgaagattc gtgcagcact tgttccagca gctaactttg gttcgatgat
    12781 ttcgttcccc ttgattatgg taggtgtatt gcttagctgg aactctacgt taatcaatat
    12841 cgggattttc gctttttctt tagcattact tttccaattg gtgacattac cagtcgaatt
    12901 taacgcgtct cggcgagcaa tccaaatttt gagtgaaggc ggactactga cggaagaaga
    12961 agtaccgatg gcaagacacg tattatttgc agcagcactg acttatgttg cagcagcgct
    13021 ttcgacattc ctgcagctgt tgcgcttgat cttattgttc ggcggcaacc gaagagatta
    13081 aaataaagaa gttgtgaaat cagcgctttg atctgagcta ataccgagag ttagctgatt
    13141 gaataccatt tatttggaat aagaggatgt gacaagaatt ttgtcacatc ctctttgttt
    13201 tgttctcata accttttttc atatacagtt catgaaccgc ttttattaac ttgccaaata
    13261 acactgtatt gtgcgttgta tccagataga aagtctccgt ttcatctgaa attttctcat
    13321 gctgatctgt aatgatcaaa tcagcatgtt ctgaatatgc ggtaatttta acagcatctt
    13381 tgcgaaataa ctgctgcaaa tggctttgaa gatgataatt tcctgtaaac tgtttggtta
    13441 tctgcaaatg gatgagtaac tgctctttcg tttctgtttg tagtaagtgt tggatcaatt
    13501 gactaaggta ttgactgatt tggtttcttt ccccattttt tgaaaaaatt gtatcgattt
    13561 tttctcttaa tttcttttcc tgtataaaag aactagaatg attggacgtg gcttctggaa
    13621 agcaaagtgt agaaaaacta ctgctggatt cacccaacag ttcgaaaaaa acaactgcca
    13681 acacaagaaa ataaaaataa attggtattt tattttctaa atggttgaga ggaaactgtt
    13741 gagttaagta agtcatcaat tgaccgactt gtcgacaaat aaggtttttg cttgtggaaa
    13801 ataaaaaacc aatctcctgt ttttgtcgaa aagagatttg atttggaaaa aaacaataga
    13861 aaaaataatt aaagtaggct ctctctgttt ctgtctcttc acaagggcga ctcactgaaa
    13921 aagaagtaaa gtattctgaa taatcatgtg tatgctgcaa taagtccatc aattcagtga
    13981 tttcagaaga agtttttgga aaatatgcct gttgtttgtt tcgtaatatg aataaagtta
    14041 acagcaagta gatatttttt tcttgttttg aaattttttc tatttgctca tctgtactgt
    14101 tcatttttag tgcatttaat tcaagtgagg aaaatggcca atcgttacct ccaaatgtat
    14161 ctgaaagaaa aaagtaaaga tagagacgga tagataactc atttccttca agagtacagc
    14221 aattttttac agataggatc cgtaaatgga atttttttaa ggaatgattg agctgttttg
    14281 tcagtttttc gagataggag ggcgatatat aaagttgttc aagtaaatat ttttttggta
    14341 cagcagtttg tggataattg attagtaaca tcaaatagtt aaaacgattg gattctttta
    14401 ggtagcataa ttttaactta gaaaaaacag ctaacttttt agtttgatcg gtttctttgg
    14461 tttggatctc tcctttatga ttagaataaa taaattcatc aatcaataaa aattgcttga
    14521 gtgatacatt tatttttcgg atcagttctt tgattgtccg ttttggaata tgtaagtcat
    14581 tggataattc ttgtaaagaa caattatttt tttgaatgac catttgtaga acaagtaact
    14641 ctttttttct tgcttcaatt agcataaata cctccttttt attctgtttt tgtatatagt
    14701 tagacaaaaa ctgtgagtgg aaagtcattt cagtctgtgt tattctcaca gagtgtcgcc
    14761 ttctttttta tataacgtta tttaattttt ttgttacctt gtttattcta ttgtttattt
    14821 cctagggtat tttgtcaaga tattcttgtt tttaaggcgg aaaaattgat ttttaatgga
    14881 tataactaaa tatgttttga taattatcaa taatattttt agaattattt atgttattta
    14941 tttatgggta gatgaaaaga gacggaggta agaatgatgg ggagagtaac aaattatagt
    15001 aaagaatatt tgctgttcaa aagtatggta tacgtggaag aatatggaat gaagtcaatt
    15061 actgcaagag agttagcaga gttctgcggt tgttctacat acccgattta tacacatttc
    15121 aaatcaatca gcgggttaaa agagaagata ttagaagaaa tcactgttta ttttgaaaac
    15181 tacttagctg aatgcagttc cgatgatgtt ttaagcattg tctacttatt gaaagatttt
    15241 ttttctatcc atgaaagtat tcgtgaaatc attgcaaaat ctgatttaga catggattcg
    15301 ctatttaagc ggccattttt ctcatatgtc aaaggtcaca cgaagatcaa agaagaaaag
    15361 tcgcttgaat tggtatggct taatgcattg ggaagtttgc gctcagatga ttcttctcaa
    15421 gattttcttg aaatgatgaa cgctgtttgg gataaaaacg aggtgacgga tgaatacttg
    15481 gaaaatatct taaaggaaca gtcaccttag gcagcaacat gaaaaagtag atcagccacc
    15541 tttatttttc gtaaaaaaga ttgtaaaatg tctaacgaaa cattggaatg aaggaggaag
    15601 cgacaacgtt accacagcaa tttatcaaaa aatatcgtct tcttttaggc gaagaagcat
    15661 ccgatttttt ttctgcgctt gaacaaggaa gcgtgaaaaa aggatttcgg tggaatccac
    15721 taaaaccggc aggattggac atggtccaaa cttaccatag cgaagaatta caacccgctc
    15781 cctacagcaa tgagggattt cttggcactg tcaatggaaa gtctttcctc catcaagctg
    15841 ggtatgaata tagccaagaa ccaagtgcaa tgatcgttgg aacagctgct gcagcaaaac
    15901 ccggtgaaaa agttttggat ttgtgtgcgg ctcccggtgg taaatcaacc caattagctg
    15961 ctcaaatgaa ggggaaaggg ttattagtga cgaatgagat ctttccgaaa cgtgcgaaga
    16021 ttttatcaga aaatatagaa cgatggggag tttcgaacgc aatagtgaca aatcatgcac
    16081 ccgcagaact tgtccctcat ttttcgggct tttttgatcg gatcgtggtt gatgctcctt
    16141 gttcaggaga aggaatgttc cgaaaagatc caaatgcaat aaaagagtgg acagaagaat
    16201 ctccgctata ctgtcaaaaa cgtcagcaag agattttgtc ttcagcaata aaaatgctaa
    16261 aaaataaagg acaactgatt tattcgactt gtacgtttgc accagaagaa aatgaagaga
    16321 tcattagctg gcttgtagaa aattatccag taacgattga ggagattcct ttgactcaat
    16381 ccgttagttc aggacgttct gaatggggaa gcgtagctgg tttggaaaaa acaatacgta
    16441 tatggcctca taaagatcag ggtgaaggac attttgttgc aaagctgact tttcatggac
    16501 aaaatcagat gcataaagaa aagaagacac gaaaaaaaag taaagtgcaa atgacaaaag
    16561 agcaggaaaa actctggacg gagttttcaa atgattttca ttatgaagct actggaagac
    16621 ttttagtgtt caacgaccat ctttgggaag ttcctgagtt agccccttct ctcgatggtt
    16681 taaaagtcgt acgtacaggt ttgcatttag gagatttcaa aaagaatcga tttgaaccta
    16741 gctatgcatt agcgcttgct acaaaaaaga tagagaatat accttgcttg ccgatcactc
    16801 aaaaggaatg gcaatcttac acagcaggag aaacatttca acgtgatggg aatcaaggat
    16861 gggttttgct agtattagat aagatacctg tcggatttgg gaaacaagta aaaggaacag
    16921 taaagaactt tttccctaaa ggattgagat ttcactgagt ggattagttc gtttattttt
    16981 ttgtctatgc tatgatggag atagataaaa aggagctgat acttatgaaa acatcaacaa
    17041 aagtaacaat cggattaagc gtagcagccg ctgccagtgt agcgacagca gtcgttgtat
    17101 cgggaaaagt aatggaaaag atccatcata tgactactcg gacgaaagta aaaaaattcg
    17161 tctatgacaa atttgatgga aatgaaaaat tactagaaat cgtagatggt ctttcagata
    17221 gtgacttgga ttctttgatg ggaatgttag caaaaatcaa atcaggaaaa aagaaaatct
    17281 ctgtttatgg tgattcaatc aaagattcaa ccgaagatgt aaaagaccgg ctaatgcatt
    17341 ttgttgaaaa aatgatgtaa gagaaactag cttttgaaca ctattcattc gaaataaggg
    17401 gttgtgacaa aattattgtc acaacccctt taatctatct ttaattatgt tcatgaagca
    17461 ataaaagata gcaaaacagt aaatcgttgg ctttttttag attgaaacca gactgttctt
    17521 gaaatttttc gattcgatat tttagagtat tacgatgaag aaacagtgtt tttgcagcag
    17581 agctgacatt gcctaattca ttccataatt cttgaatgat cacttccatt tcattttgtt
    17641 tgatcagttc tatgtaactt ttgatcaact tactatcttt tacagtatct tttgtatagt
    17701 aatgtaaagc cacatcttgc atagaaaaag tacggctgtg agtataaaga ttgttttgct
    17761 ctgttaaaaa aatttttctt tcttcagcaa acaaagggac gaggtcggtg ccaggtgaat
    17821 ggaaagaacc aacgaataca gacgttgtcg tatcaaaatc agcatctaaa gatagaaaaa
    17881 taccgttgat ttcagtagca tcaagataat cacggtttat ttgttcgact aagagcgcat
    17941 ctgtgtctgt ataaaaaaag aaatcagcag aatagcgaaa taattccaaa atagtatctt
    18001 g
//
LOCUS       DAXLPC010000056        17951 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.056, whole genome shotgun sequence.
ACCESSION   DAXLPC010000056 DAXLPC010000000
VERSION     DAXLPC010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.056"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..372
                     /locus_tag="ACF3UE_001806"
     CDS             <1..372
                     /locus_tag="ACF3UE_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3635202.1"
                     /translation="CDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDL
                     LTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQKF
                     LNRSHKGFQQVTDTLVSMFTE"
     gene            709..948
                     /locus_tag="ACF3UE_001807"
     CDS             709..948
                     /locus_tag="ACF3UE_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635203.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(1310..1570)
                     /locus_tag="ACF3UE_001808"
     CDS             complement(1310..1570)
                     /locus_tag="ACF3UE_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635204.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1755..2252)
                     /locus_tag="ACF3UE_001809"
     CDS             complement(1755..2252)
                     /locus_tag="ACF3UE_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFD3635205.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANLNINAF
                     SFINN"
     gene            complement(2382..3092)
                     /gene="budA"
                     /locus_tag="ACF3UE_001810"
     CDS             complement(2382..3092)
                     /gene="budA"
                     /locus_tag="ACF3UE_001810"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFD3635206.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(3105..4769)
                     /gene="alsS"
                     /locus_tag="ACF3UE_001811"
     CDS             complement(3105..4769)
                     /gene="alsS"
                     /locus_tag="ACF3UE_001811"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFD3635207.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4974..5636)
                     /locus_tag="ACF3UE_001812"
     CDS             complement(4974..5636)
                     /locus_tag="ACF3UE_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFD3635208.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5646..6461)
                     /locus_tag="ACF3UE_001813"
     CDS             complement(5646..6461)
                     /locus_tag="ACF3UE_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3635209.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6723..7166)
                     /locus_tag="ACF3UE_001814"
     CDS             complement(6723..7166)
                     /locus_tag="ACF3UE_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HFD3635210.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(7300..7638)
                     /locus_tag="ACF3UE_001815"
     CDS             complement(7300..7638)
                     /locus_tag="ACF3UE_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFD3635211.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7626..8003)
                     /locus_tag="ACF3UE_001816"
     CDS             complement(7626..8003)
                     /locus_tag="ACF3UE_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFD3635212.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            8227..9420
                     /locus_tag="ACF3UE_001817"
     CDS             8227..9420
                     /locus_tag="ACF3UE_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3635213.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9586..10008)
                     /locus_tag="ACF3UE_001818"
     CDS             complement(9586..10008)
                     /locus_tag="ACF3UE_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635214.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            10379..11053
                     /locus_tag="ACF3UE_001819"
     CDS             10379..11053
                     /locus_tag="ACF3UE_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635215.1"
                     /translation="MKKLVALFLVAGSLLSGCGATTSTTQSTSSAQASSSSTTISEST
                     ADSSKEQEQIEKKKEEEKQKAEKAALEKKVTEAESALSQAEANPTKENYATASAAIQA
                     LPENKQELTSRLAAIDSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQ
                     AAAEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPC
                     SKCYGN"
     gene            complement(11215..12387)
                     /locus_tag="ACF3UE_001820"
     CDS             complement(11215..12387)
                     /locus_tag="ACF3UE_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFD3635216.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12593..13891)
                     /locus_tag="ACF3UE_001821"
     CDS             complement(12593..13891)
                     /locus_tag="ACF3UE_001821"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFD3635217.1"
                     /translation="MHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYP
                     SKDTAVPADATPFASVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLS
                     LPFYNPNSSDPDKPLDTIHLYAKNVIKESNIKIQKAGNFSGVDKLAGAQFQIKNSENQ
                     FVTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVETKAPDGYQLTNPQ
                     KETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTITVENVQNYGDFHF
                     IKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWSDEVTGSDWEEVKL
                     ISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDDDPTTSDETTIDNQ
                     PKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(14019..14534)
                     /locus_tag="ACF3UE_001822"
     CDS             complement(14019..14534)
                     /locus_tag="ACF3UE_001822"
                     /inference="COORDINATES: protein motif:HMM:NF037639.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HFD3635218.1"
                     /translation="MDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFT
                     SSKDGTFSVHGLSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEP
                     KANPTNNGKTPVQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKK
                     QQKGNNRREIK"
     gene            complement(14607..15521)
                     /locus_tag="ACF3UE_001823"
                     /pseudo
     CDS             complement(14607..15521)
                     /locus_tag="ACF3UE_001823"
                     /inference="COORDINATES: protein motif:HMM:NF027869.4"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
     gene            complement(15518..17845)
                     /locus_tag="ACF3UE_001824"
     CDS             complement(15518..17845)
                     /locus_tag="ACF3UE_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBG domain-containing protein"
                     /protein_id="HFD3635219.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         5214 a         3555 c         3110 g         6072 t
ORIGIN      
        1 tgtgatgact ttaaggctgt ttatcaagct aactcaaaag aagaagcgaa taccttctta
       61 tccggcatga ttgagaaatg gaagaaaaac tatcctaaag tgacgcagtc actcatagaa
      121 aaccaagact tattaacttt ttatgatttt ccacctagca ttcgtagaac catttactca
      181 accaatctaa tcgagtcttt caataagcaa attaaaagat acagccgtag aaaagagcag
      241 tttcaaaatg aagaatcact agaacgcttt ctagtcagca tttttgatac atacaatcaa
      301 aaatttctaa acagaagcca taaaggtttt caacaggtaa ccgatacatt agtttcaatg
      361 tttactgagt aactaattat tttgcaggag gacaatttat ttacacaaaa ttattgacgc
      421 tcccagctat cctcctagca actatttaaa tacccaaaaa aattacctct agataatatc
      481 atacctacgt tttcacttat aaattttttc ataaaaaaag cgtttagagg cataatcgtt
      541 aatacagatg gtaaccaatg tatctggttt gaactgggat atcaccctct ccatatatgt
      601 attactaaga ctaatagata ctataaaaga cttgatagtt ttgcattgat tttgcctaat
      661 actgagcata ggtgtatgct aaacgatact ataaggagtg tgtacataat gaaaagaatt
      721 ctgtttatca gtttatcaaa tttattgtta cttactgctt gtgggacttc tgcatcaaag
      781 aacatacctt cagatacgca aatttcgaat agtatcgatt caacaatttc tacaaatgag
      841 aaaaattctc cggtagaaac ttccgatata aaagtttcta cctctgcaaa aaacagggta
      901 aagaaactgt cagcacgtct cctttatttc aaacaaactc tgaattagct tcttcatctt
      961 cttcagcaaa taatgatgat agtttcgcgt ttactcctaa ctaaatgcaa cctttacaaa
     1021 tgctttacga taacaagcct gagctaaatg atcctgatat cagttttgca ttttttgaaa
     1081 tgattggatc ggatgatctt tttaaaacta ctagtttgtc tatccgaaaa taggacagtt
     1141 ctggcagtat aggtttttat cgagtttctc caccaggcct cgttacagag acagattctc
     1201 taggcgaacc ttttgaataa atcaaaaatc atgaacaatc actgccaact aaataaagtg
     1261 ccttcaaaag cttggtcttc tcgcttttga aggcacttta tttaaatctt tatgaaacta
     1321 aagtatgttc atatttgttg ctatagttat atagatattc tgttgtttcc aactcataaa
     1381 cgtgagtata ttttgccact acttttccgc atttttctaa tatttcattg cgatcgacgt
     1441 catgatattc gtctacgcag atcacaacac aattttctaa tttactgatt acttctccaa
     1501 ccactttttg tttcaagcca ataggttggc aaatatattt ttttcctaaa atgatagttt
     1561 cgttattcat atttcatcca tccttaatgt ttttccatta tttaaaatga taataccatt
     1621 aaaatatgat tatgaaaatc aataacactt gtgattttat aaaaaaataa aaaaaccgaa
     1681 aaacagaaat gcccactgtc tttccggctc tttttattct tgatttctct tcttttttgt
     1741 ttcaatagac gattttagtt attaataaat gaaaaagcat ttatattcaa atttgctaat
     1801 aaaagatcta catatttttc tagaaatgct tgatcgattt catcataccc tttcgttact
     1861 ccgcaatcga tatctaaaac accgattaaa ttaccttctt ttaccattgg cactacgatt
     1921 tctgattgtg cggctgaatc gcaggaaatg taatttgcat gggttttgac atcatcaacg
     1981 atcaatgttt cttgtttttc agctgattct ccacaaactc cttttcccat cttgatacgt
     2041 gtgcaagaaa ctcgcccttg gaacggtcct aaaatcaatt cattaccatc gaataaataa
     2101 tatcctgcaa agacagtctc aggcaaagtc tcattcaaca atgcagatga atttgctaaa
     2161 tttgctaacc agttatcttc tgcttctaat aatccttgtt gctgtaataa taaaatttcg
     2221 tatgcatctt ttttctgttt ttctgtccac atgataaaaa ccgctccttt ttgatctatg
     2281 gagaagatta tagctcagtt tttttgtaaa cgctaggttt cctcctcaaa aaaacgagat
     2341 acgtcaggtt aatcaccttg aacgcatctc gctgtctttt tctattctgc ttgttggatt
     2401 tctgctgcta aatcagcata atcaatcgtt tcgtgaacaa aagtcggatc atcaactgga
     2461 aaatgctgta caagggacga gatgcggcta atctcaactt ttccttcagc cacttcaaaa
     2521 tccattacat gtccgccaaa tgtatgtgta tcatcgataa aatgcaagtg aaatcccgct
     2581 gcagcaactc cttggaataa ttcaggcgta aagaacccga ctaatgttcc ttggacattg
     2641 ctttgttgga attctggttg agactctgaa atttttgcta gtcttctgta aggtttttct
     2701 tgcttcggca tgatacggat gtgcatattt ttgaataatc cagttatctt cactgccaaa
     2761 aataggtttt ccccggcttc tcttactaat atgtcttttt tcaattgttc tccatctgca
     2821 gtttttgaga cagaaaaact agtatctggc gtaaaatctg taattgctgc atagggggta
     2881 agttcacttc catctaattg ggcaactgag ccatctgatc ttccttgata agctacgcca
     2941 tctaaaaaga tgacttcacc atcaagccca tgcaatgttc ccaatcccag agttcctttt
     3001 tctaatatat gagcaatcgt ttctgttcca tccatcaagc cagccatcaa agctcctaat
     3061 gtcccgtgct ggtataagat tttttcagtc atgtcgacac ttccttaata gaattgatct
     3121 ggtaagattg tttctcccaa tttctcatta tcacggtaat caatcggaat atcaataatt
     3181 acgggtcctt ctgtcgcaaa tccttcttct aaagcttttt ctaattcctc tacacttgta
     3241 gctcggattc ctttagcgcc aaaagcttct gcatatttca caaaatcaac tggaccaaag
     3301 tctacacctg acgcccgctg atatttcatt ttttcttgga actctaccat attgtagtgt
     3361 ccatcattcc aaatcaaatg aacgatattc aattttttac gtaccgccgt ttctaaatcc
     3421 tgggcagaga ataaaaatcc cccatcgccg gaaactgata cgatttgtgt atttggacgc
     3481 accaatgcag cagaaatcgc ccatggcaat gcaacaccaa gcgtttgcat accattactg
     3541 aataacaaat gacgaggttc ataacttcta aagtggcgtg ccatccaaat ataatgacta
     3601 cctacatcta cggtaacagt catatcatct gttacttttg actgaagcgt gttaataact
     3661 tctaaaggat gcaagatacc tgcttctcct tttgattgaa caatgtcccg ctccgttaat
     3721 tctgcttgaa gagatgctaa atattctttt gcatcttctg acacttgttg aggctctaat
     3781 gaacctgtca ataaatcaag agtggctgag atatcaccga tcaattctct ttcaggctgc
     3841 ataaaaggat cgatttcagc tggcgcttca tcgatcacaa tgatccgcgc atctttttcc
     3901 gcattccagt ttcttgcttc atattcgatt ggatcatagc caatagcaat aactagatca
     3961 cttcgtttca aaagcatatc tcctggttgg tttctaaata aacccacacg accaaagaaa
     4021 tgcgcttcta attcacgtga gatcactcca gctgcttgga atgtctctac aacaggcaat
     4081 gctgtctttc caactaattg cctgatggct aacgtttctt tttcacttga tcctcgcata
     4141 cctactaata gtaccggtag ttttgcttct ctaatgcgtt cagctaggta acggatatca
     4201 tctgcagaag cagaacctaa tttaggatcg ctcaatggct tgatgacatt cccttggaca
     4261 ggtgcatcca ctacatcttg cgggatactg ataaagctcg cgcctttttt tgaactctta
     4321 gccatacgat aagcattggc aatcacttct gaaattgttt ctggatcttg gatttctgca
     4381 ctgtattttg tgattggctg gaacagtgct gcattatcca tgctttgatg ggtcaacttc
     4441 aatagatcgc ttcgttttac ttgtccggca attgctaaaa ctgggtcacc ttctgctgtc
     4501 gctgttacca aacctgtagc taagttacta gcaccaggac cacttgttgc gataactact
     4561 cctggctctc ctgtaatacg tccgattgct tgtgccataa atgcagcatt ttgttcgtga
     4621 cgagtcacga ttaattcagg accttgatcc tctaattcat taaatacacc atcgattttt
     4681 gcacctggta taccgaatac ataatcaaca tgatgattaa tcaaactttc tactacagat
     4741 ttcgaacctt gtttcatttt ttcgtccatt gaacatcgtc ctttttatgc tttattttta
     4801 attattagtt agaaataatc acaaataatt gatacagttt ctaaacctgt ttcattcaaa
     4861 agtatagcac gttttatttc atttgtttag ccatatgttt caaaaaatga aaaagaatga
     4921 cagtttttac ataaaaactg tcattcttaa ttgaaagttt caatttataa agtctacaga
     4981 tccatagttc tcatcaattt acgattgttg aagtaaatca aaccaaatac gatagaagga
     5041 cctagtagaa tacaccattg gggctttacg aaaaagaaga gaaacaaact tgtcaatagt
     5101 aaaaaatcta gtaaactcac ataccatttt ttcaacgtat agtagaacgc tatccgtaga
     5161 acttgatttg gtttcgacgc tggatttctc acctgaaaat accagtagtt gatgctaaag
     5221 gaaactgata aacaagcaag taaaacaaac aacggaatca accattttcc ataagaaaaa
     5281 cgtataaaaa agaaacaatc aaaaatcatt atcacactaa ctatccaagc aaatagccaa
     5341 taaaaaaatc cctttagcca aaattggcga aacgtcttta tgaacaaacg tactggtgaa
     5401 aaactttttt cttttgctaa ttcttctgtc atacctatca tcacgatgca acctggacca
     5461 ataaaaagta aagaaaaaat aaaggaaaag acattccttc catctatcga caaaaggaac
     5521 gcagctgcta tatacaagat attgacacac caaaaacaaa ggctacttgc caatgattga
     5581 tacaaccaat aaaagaattc catataaaca tttttgtcaa aacgctgctc tttcataatc
     5641 acctcctatt ccttcattcc tgatgaagcg atcccttcta caaaatattt ttgcatcgct
     5701 aaaaatataa aagcaacagg aagaacagaa acaactgagg cagccatgat taatgcgtac
     5761 tctgcatcaa atagcccaat aaacattttc aaccctaact ggattgtttt attttccgta
     5821 gaagacaaat aaatgaatgg ccccatataa tcgttccatg tattaacgaa tgtgatgatc
     5881 gtcaaactgg caatcgccgg ttttgtaaga ggtaaaatga tcttgcgata gattccccac
     5941 tctgataagc catcgatccg cgcactctca cataaagaat ctgggatact actgtagtat
     6001 tgcttcaaca agaacacacc aaaagcattg aacgcttgta atagcaccaa cgaccacaac
     6061 gtatatgtta aacccacttt tctcatcata atgaactgcg ggatcatata agactgccaa
     6121 gggacagcaa tcgtgccgat atatgctaaa aataaaatat cgcgcccttt aaaatttagt
     6181 ttagaaaacc cgtaagcagc aaaactagaa gtaaacaact gaatcaacgt gatcacaacg
     6241 cttaaaaaag ctgtattctt aaaaaatgtc actaaaggaa tacgagacca aataaccaga
     6301 taattctcta aatgccaagt tttagggatc cattgaatcg gaatcgtgaa cacttcatta
     6361 tttgctttga atgaagcaga aaccatccat aaaaaaggaa tgatcgtcaa taaagctaat
     6421 acaatcagca gaatcatacc caaccattga ataaagggca tgttttttga acgaattttt
     6481 gctttttttc tttcatttcg aacacctcca aagttataat cttcatttct ttgtaatgat
     6541 tacaatccag aacaacggtt attatagctg attcatttcc gttcttctta tgtttgtaag
     6601 cgcttattta acaagttatg taaatctctt tatttttttt gatttaaaaa tgaaaaaata
     6661 caaaagcaag actgtcatac gtctcgcttt tgtattgaaa tttcttcgat tagagatact
     6721 tattactgtt caaaagcttc tttgaaacgg tgaatcaatt cattgactac aggtgataaa
     6781 atccgattct ttttccagac tagcatgcag ttcgtttcaa tcattgggtc aagcggaacg
     6841 aatgtcactc gctttgaaag atgacttaca gcaccttcta tgactaaagc agcacctacc
     6901 tgattctcaa ttagcgcaaa tacattgaaa atcaaattgt acgttcctgt gatcagcaac
     6961 tgctcctttt ttatgcctaa ccagtcagca aacattcgct gtatttctgg acgctttgag
     7021 atcaaaagag gtacattcgc aaagtcttct tttgttatca cgtctttttt tgctaaaaca
     7081 gaattttcta aaatgagcaa tccccatttt tcctttcttg gtaacaaaat cgtttcgtat
     7141 ttctctgtat ctactggatc tagcaaaatc gctaaatcta acaggctttt ttctagtcac
     7201 tccgtgatat catcacttgt tccgctgtgg atatgaaatt gaacgctggg ataatcacgg
     7261 atcaactttt ctagtaatag tgccaatgta ttcgaattat cagcttccac acagccgatc
     7321 gtaaatcggc cgctgaataa ttgttttttt ctgttctcga attcttgagt ggtttgattc
     7381 gttaaatcta aaatttcttc tgctcggctt ttttagaaaa taacctgctt ctgtcaagat
     7441 cattttgcgg ttttcgcgta caaacagttc tgttcctagt tcctcttcta actccttcag
     7501 ttgtcggctt aaggttggtt gtgtaagatg tagaacttct gcggcttgag agattgttcc
     7561 ttcttctgca attgtccaaa aatattttag taagcgtaac tccatagcga tgctccttga
     7621 tttttttact tgatacattc cattttattt ctagataaca cacgatcata tttcttgatt
     7681 tttccttgta aacgttccaa acattcttgc atttcagcaa tttttttcgt caaaagttca
     7741 ctttcttcaa tcaaaagctt acgccgctca aatacagttg cttctccttc gctagatagg
     7801 cgaatatatt caatcaaaga ctcgatcgat aatccggcat ttcgcataca gatcgtaaag
     7861 tcgacccatt ttaggtcttc ttctgtataa tcacggattc cgccttttgt ccgattaact
     7921 ggtggaatca acccgattcg ttcataatag cgcaatgtat cggccgaaat gcccttttct
     7981 tcactgactt gtttgatatt catctgatca ctctttctct taatttcttg ccactttact
     8041 tatgtatttt atttattcta caactttaag tgtactccaa gtcaatactc atttctatta
     8101 aaactaagct ggattatcta tatcggttgt ttgtgtatta tttcaaataa aaaagtcttg
     8161 tttttttatt cttttttgga tatactttta acaatttagg gaaattttag gaaaaggggt
     8221 ataaaaatga caacgtatca gcgaaagtta ttattatcga catcggcggg aattgcttta
     8281 gagaatatgg atattatgtt tttagctttt tcattatctt caatgattac ttcttttcat
     8341 attagtggta cgcaagcggg tttcatttca acgatcacta atttggggat gctcattgga
     8401 ggtatttttt ttggcatcat agctgataaa tatggacgtg tgaaagtatt ttctcaaacg
     8461 gtccttctgt tttcgattgc ttctttattg atgtattttg cttcaaacat ctacttggtt
     8521 tatctctttc gctttatcgc aggtgtagga gcgggaggag aatacggggc gtgtatgtcc
     8581 ttgatttccg aaagtttttc aaaaaaacaa attggacgag cttcttcggt tgctggtatt
     8641 ggtgcgcagg tcggtgcggc tttggctgcg attttagctg ctgtgatcat tccaacgttt
     8701 ggttggaaga tgttgtatgt cgtaggtgta ctgccggtgt tgatggtctt gttcattcgt
     8761 cgcggcttga ctgaaccaaa ggaattcaaa tctgtacaat ctgccgaaaa gaaaaccaaa
     8821 cttagcagac tgtttgaatc aaaacatctt gcttggcaaa catgtggcct tagtatcatg
     8881 gtaactgtcc aaattgccgg ctattttggg ttaatgaatt ggctgccttc aattatgcaa
     8941 aatcgattag ggctttcggt ttctgggtct tcattgtgga tggtcagtac tattttaggc
     9001 atgtctttgg ggatgatgac ttttggcata atcatggata aattggggcc taaactagcc
     9061 ttttctttgt ttttaatttg ttcatcctta tctgtctatc tacttgtgtt agcccatagc
     9121 cagtggagtt tggtagcagc cgctgtgata gtcggctact ttatcaatgg catgtatggt
     9181 ggatatggcg cagtgattag tagtttgtat ccaacagaaa tccgcgcgac ggcgaataat
     9241 ttcattatga accttggacg agctgttggt ggtttttctt ctatcgtcat cggtttcttg
     9301 atggatcatt atagtttaac tgccgtaatc ttgtttttga gcggtattta cctagtcagt
     9361 ctgctggtct tgacaactct tactggtgtt acagcattaa gggaaagctt gcagcattga
     9421 tagttgagtc tgtaaatgac aagaaagagg tgtggcaaaa gcttgcatct gcggtaataa
     9481 gaccagccaa atcaaaaaca tgagacactg tttccgtttg gctggtcgta ttacttgatg
     9541 cagggcagct ttttcaactg ctaatttcct tctatctggc ggctactatt ctttgacgtc
     9601 cgtcatttca aagtacttta ctaataactt agcataacga aaaactgtgg atacactcgt
     9661 atattgagcg tctgcataat cttccaaatt tttctcagga tgttgataca tgaattcaat
     9721 caaatgataa ttatatgatt ttctgtagaa atgaagataa ataatgtaga ttgggaagtt
     9781 ctcctgcttt tccatagaaa agcgccgatt attctcattc ttcaaaatga ccttatcagg
     9841 atatttttgg aacaattctt ctaaatctgt tagataattc aagatagact tacttgatac
     9901 cttcaattcg ttttgtagtt cttctattga acaccaacgt tctgtttcaa gcagtaaatg
     9961 aatcatttta attttctttt gagaaacttt tgttaaaaaa gtctgcatat tttctcctcc
    10021 tgtatctact ttactatact acatacaaga aaaaaaacgg atacaaatat catattgtca
    10081 caccgtcaat agtgcataaa cctgttatta tttctctttt tttcctaagt attctattga
    10141 tatgaatcat ttaatcgttt attatataaa tgtcaataat ctaataataa aataacgtac
    10201 atattttatt attgcatact taataacaga actatagcaa aaaatcccgt gtatcaaaac
    10261 gggattagat taagtttcct caatcactat tcataacaca attattataa caagtaagta
    10321 aacaattgaa aaggacattt attgaaaacg gttgtttttt acttaaggag gaaatttagt
    10381 gaaaaaatta gttgcattgt ttttggtcgc aggaagtttg ttgagtgggt gtggtgctac
    10441 tacgtctact actcaaagca caagttcagc tcaggcttcc agcagcagta ccacgatctc
    10501 cgaaagtacg gcagattcat cgaaagaaca agaacaaatt gaaaagaaaa aagaagaaga
    10561 gaaacaaaaa gcggaaaaag ctgcactaga aaaaaaagtg acagaagcgg aatctgcttt
    10621 gtcacaagct gaagcaaatc ctacaaaaga aaactatgca actgcttcag cagctatcca
    10681 agcgctacct gaaaacaaac aagagttgac aagccgtctt gctgcaattg attccacaat
    10741 caaagcaaaa gaagcagaag aagaacggaa aaagcaagaa gaaattgcac gacaacaagc
    10801 agaacaagcg caacaagaag caatcgcaca gcaacaagca gaacaggcgc gacagcaagc
    10861 agcagctgaa caggcctctc agcaggcaca agccgcagct cctgagcaaa ataatgaaca
    10921 aactgtctat gtcacaccga ccggttcaaa ataccataca cataaatgtg gaaatggtac
    10981 gtatacccct gccactttaa gcgaagctca agctcgtggt ttaacccctt gctccaaatg
    11041 ttatggaaac taattcaaaa gttatactat aataataaaa ttcttctgaa acataaaaaa
    11101 atagaagctg gcgttccaga tagtaaacca aaaatagcag tttacacgtc catttcgtca
    11161 gcttctctct tttttcattt agtctgttcc ctctgctttt ttggacatct tcattcattc
    11221 tttctcaatc aaatagtaca cctctttttc ttttcgcagt ttatatcttc cttttttcaa
    11281 tttcattgaa aactgtttcg aatgtttatg ttttacatgg attttaagca ggagctcctc
    11341 atgttgcaag cgatagttcc tgccttttaa atcagaaaat ctcactagtc cgtattcatc
    11401 agaagctttc acaaatggaa ctttttctct agtaatatag tgtttgccgt tgagcgtttt
    11461 tacagaaaag accattcctt cgattggtcg tccgtttgtg ttctttacat aaaaagataa
    11521 aggatagttt cgcttagcga tggccaaaga atctaaataa gcgatgagta gccaaactaa
    11581 gccgattgat ccaagtagta taccgataaa ccaaataaaa aatttccatt ttttccattg
    11641 atcaattcct tggatcgctt tttttgcctc ttttgcttga taaggaatac gatgccccgt
    11701 cacaagcagt cgatgtgtat tgaccatata aggagtacag gtaagcaaag tcacgagatc
    11761 tctgcctttt tggataccca aagaatctac ttcatcaggt aagaccactt ggattttttc
    11821 tacttgatac gccaatgtct ttccattgat ctggatgaaa aactggtctc cttttttcaa
    11881 cttaggcaaa tctgtaaata attttgcttc tgggagtcca cgatgcccag aaagaacggc
    11941 atgggtgttt ttcccgccag tcggataaga actttcttcc aataatgacg ttcctttttg
    12001 caaaaatatt tccgttgtct gatcgaatat aggtaagctg acattgattt ttgggatttc
    12061 gatgactcca agcatatgtt ccataaaaaa ggcattacta ggtaaatctt ttaatgcttt
    12121 tgcatcaact gcttggttga aactgcctat ccctggtgat acgttttgct ctgccaactg
    12181 ttggtttttc tttgtcattt tttcctgctg tttttttatt tcctctgaat tcttattcga
    12241 tgcttgcttt tgataatgga tgatcatttg ctgggcaaga aaatcattca gtgaatcttc
    12301 tacaaaagga taagaaaaga tcccgatccc aacgactaaa atgattgcca tgaagatgtc
    12361 cagtattctt attctgcttt tattcatcat gtccacctat tttctaatat gtatatgaag
    12421 aggttgtgaa atcagcgcct tgacctgagt attcgctcaa caaacggcaa aatagttcct
    12481 cctattttgc cgtttgttga gcgaatacca agagaccgac cacttgtcac aacctttctc
    12541 cccatttgaa tcactatcgt ttatttatcg tatgattttt gtttccaata gtttaagctt
    12601 ctgtttcttg atggcgtttt ttgaagtaga tcactgctcc tccaactaaa gcagtaccta
    12661 ccaagatgaa tacgatgatc cccataccac cagttgaagg caagattcct ttaggttggt
    12721 tatcgatcgt tgtttcatca gaagttgttg gatcatcatc tactgtaaat tcagtgtacg
    12781 cagcttcatt cttaggtaat gcgtagcctt ctggtgcttt tgtttcttga aggcagtatg
    12841 ccccttgttt cagcccttcg attgaaaatt tcccttctga atcagaaatc aatttcactt
    12901 cttcccagtc agaacctgtg acttcatctg accaagcata tgggtattct cctgaggcaa
    12961 gatttgctat ttttttcatt aatttaacag ttggatcttt tgctcttaga atagaaaatt
    13021 ctgcatcggc taatttttct tgcgtgttca catcttgttt gatgaagtgg aaatcaccgt
    13081 agttttggac attttctaca gtaatcgtgt tatccgtagt tgtattttcc cgattgacta
    13141 caccgtttgg attcccaaga ttggcttcat ctgcgccatg gatgataccg gttgtttgtt
    13201 gcaattttcc gttttttact ataaaagtag tttctttttg tggattggtt aattgataac
    13261 catctggtgc ttttgtttca actaaagtat aattgccgtc tattaatcca ttgacactga
    13321 tggatccttc agtatcagtt gtgaatgtca acgctgactc agcaggatca tagagagcga
    13381 caccagtgtt ttcatcaaaa ccggtcacga attgattctc tgaatttttg atctggaatt
    13441 gcgcccctgc taacttatct acccctgaaa agttcccagc tttctggatt ttgatattgc
    13501 tttctttgat gacattttta gcatataggt gaatcgtgtc taaaggtttg tcagggtctg
    13561 atgaattcgg gttataaaag ggtaagctta acacgatatt tggcgacgtt tcgacaccgg
    13621 gctttggtgt ttctacaaag acgtatacag catctttccc atcagattta cctggaagag
    13681 tcaggttagc taatccttca ccagaagtcg ttacacttgc gaagggtgta gcgtctgctg
    13741 gaactgctgt gtctttactt ggatagtacg tagcagtgat gtcatatacg ttgaattcaa
    13801 cgccgttcaa cggttcgcta ttcggaaatg tcaattccgt tccgttgttt atttgatttt
    13861 ctggtgctga agtgaatttc aatttatgca aattaaccgt aacattttct ggtgtaggtg
    13921 atacggccta gaaacctctg cagttcctag gccgagaacg aaaggaagca gcatgatagc
    13981 agttcctaaa aacgtccata tttttgtttt gatgtttttc attttatttc cctcctattg
    14041 tttccttttt gttgtttttt ataaaaccaa gctgtccctg ttgaaaggac tagcaacaac
    14101 cctaaaattg agaaacctcc aagcatctct tcgcttgttt ttggaaagct tcctccattt
    14161 ttttcatttg atggaccatt tgtctgcatc tgaactggcg tttttccatt attcgtcgga
    14221 tttgcttttg gttcgttgat gatttccaat ggtataggat gaagcggatc ataactgcct
    14281 ttttcaactt caaagagaat ggttgattga ctcaatatat atcctttagg cggtttaatc
    14341 tccactagtt cgtaacttcc aaaagacaat ccatggacag aaaatgttcc atctttactg
    14401 gaagtaaaaa tcgttgctct tgaatcatct ttggctaccc aatgatttat cccgttttct
    14461 tgcgctaagt attggtcatt ttttttgact agaaattgag catctgctag tttttgtttc
    14521 gtttgccgat ccactttgac aaattgtttg cctcctgttt ggatggcaag atgtgtttct
    14581 actgtttgat tgtcagtcgt caaacgtaca tcgttatcaa atgtcgtttt ttcactgttt
    14641 tctttcaatg tcatttggta acggatcgtt aattttttcc cagcaaacga actaagatct
    14701 tttccagaat ctgataagac aaaaccatgt tttgtttttt gtgtgtgaaa tgtatgaatc
    14761 ttgtctccac caatcaaaaa atcgatcgtt tctggttcta gccataactg aggatcagct
    14821 gtatctttga tcgtataggt tcctatctcg ttgatgttct caggaattgt tacggtgatg
    14881 agataaggaa ctttatcccc atctgcaaaa tctgtctgct tattctctac tgtttttgtt
    14941 aatgtgagtg cagcaggtat tttttgttcg ctctttggat acaagtggat ggtcgtcaat
    15001 ttatgattag atgaatctgt cacaggaagc acaacgacaa atggtgctga tttttctttt
    15061 acttaatctg aagtctttat ttccgcaaat cggtaaacag cgtcacgacc ttgctcatct
    15121 ttgtccgatg cactaaaaga agcaatgccc tcttcctcgt ctactgtttt tgtcacattt
    15181 tctgccagta ttttttcact atcacttttt tgtgctagtt ttctttgtgc gtcttccaca
    15241 ctacttcctt ctgaccgcag cttgtaaaat tcatccgaga catcatatat agcgaaagta
    15301 acgccgttca acccttttac tccttgaaag ttatccggga tatttattcc gtcgttttga
    15361 ctgatacttg gcatcttatc gctttcgaac attcgattat gcaaagtaaa tgtaataggt
    15421 gattctctag ctgacacagt cggagaacct ataaaaaaga ccagtaggat aaaaaagaga
    15481 acagcaaata tatccacacg tacatttttt gtttttttca tcgctgttca cctgcttttt
    15541 tcttacgatg gataaaataa aagaagccag aaaaaataaa gatcagtcct aaaaagacaa
    15601 agggcagtag acctatccca cctgtcgaag gaagcaagag agtcggattg atcgtcaact
    15661 tagcggtatc tgttgcgata atcgtataat tattgtttac acttccttcg cctaaactaa
    15721 tcgttactat ttgtgatcca atatctgtcc ggctgttaac tgttagggta taatccaatg
    15781 attcgcctaa gacaacaccg gtaacgtgga gatttccaac cgaaatcgag tgactttggg
    15841 catcataatt aaaggcagcg tcatcgacag taatcactgc gttagcttta tagatggtat
    15901 aagttcctga tgtgttggct atatcagtaa atgacaactt gggatttgct gctttgactt
    15961 tgtctattcc gctattcgtt agtttaattg tatagctgcc agcattaacc atattttttg
    16021 ctgattgtgc atctgctgtg taatccatac tgctaagtgc cacttgtact ggagtaagcg
    16081 aactagtgac accctctgct agcttgacat ggattgacgg gacacctgct tttccatcat
    16141 atgtcttact gccactgagc tctaccgcac cgctgatttg cttaatcgta tagacatcag
    16201 atgtctgcac gatagtaaat aaatagtttg ttctggcagc tagtttagct agtccgcttt
    16261 ttgtcaattg ccaagacgta taggttccaa tttcagtagg cgcagttact tcaactccct
    16321 tttcattcat cgctttgaaa tcagttggat tccatgtgat ttgatcaata ctgagatcat
    16381 tgtttaaaag ggatgttgat tctgttttat cattaaaggc atatttaacg atcggtacaa
    16441 cagaaagacc atcatagtac ttactgccat ttgcattgat tgatactgtt gcatttgtct
    16501 tataatatag gatgacttca gaaatctgtt ttccatttgc gtcctttacg attacatttc
    16561 catttgtatc taaactagct aaaacactca ttgctgattg gttctttgtt tctgtcgctg
    16621 aaacagctgt aaaggtatat ccgttgatag taggcgtatt agtcgtcagg tcttgtgcag
    16681 cacttccgta agtaagattc attattttag aaggagcaat catctgtcca aaatagtctt
    16741 gatacttaat agtgattggt gtttgtttgc ctgtataggt caccgtatcg acgttacttt
    16801 ctagggctgt gaaagaaccg tttgtttgtg caaaagaata gcccgttact gctgttggag
    16861 tgataaccac tttgtcaccc acatggattc cagataatgt agtcccgtac gttccgattt
    16921 ttgctgctcc accattgact gtataagaaa aagttcctgt ccgattcgca ttgacctgaa
    16981 ccgttgctgc ttgataggtt ggaaaatttg aaacatttcc cttaccatca acgatctgcc
    17041 catttttgat cgagtacccc gtgaatggaa tatcatttgc taactgtata ccgattgaaa
    17101 aagtactcat acctcctccg gcaggaagcc ctccccatgt tgagggtgta aaagaataac
    17161 ttttatccgc attgggtgta actgaatcga tcgtatttcc agcggtagcc acccccatat
    17221 agatactttt tgggaatgtg atagtagtac catttactgt ggagccaata aacagattat
    17281 ggatatctgg acggttatca ataaaagcga ttgctttggt tacgccttgt aacgcagttt
    17341 tatccgcact catcgatccg ttaaccgcaa caatgactcc atctttggca tatatcactg
    17401 tatatccatc tggtatggta tgtccgttga aattcgcagt ggccgcaaca gtactaaatg
    17461 tctggcttct acctgtttct gaataagctt tctcccctgc tgcttttgct gctgtgattt
    17521 ctttttctgt cggatcaatc agttgagtcg aggatgtggt tgaggttgtc tcgttgttgc
    17581 tagactgatt ggtgctttct atggactgta tttcagaata gggtggacta tttgtctcct
    17641 ctgtcgtttg gttagcaaaa tttgacgttt ctgtataaac gtttacataa atacttgata
    17701 agctccctaa gaaagtaaaa atcaagatga tcgaaatcat aatgggatgt aagtattttc
    17761 ttttagatac agctttgagt ctagaaacaa aatgtttttg acatatacgt tggattttat
    17821 tttgagtttt cttaatcatt ttcatccctc ctctcaataa aaaatcatca aataatcctt
    17881 tacacgttat tctaaattta atttttatta ttttattgat gtatagaaag tttggggctt
    17941 tttttctctt t
//
LOCUS       DAXLPC010000057        17515 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.057, whole genome shotgun sequence.
ACCESSION   DAXLPC010000057 DAXLPC010000000
VERSION     DAXLPC010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17515
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.057"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            80..1471
                     /locus_tag="ACF3UE_001825"
     CDS             80..1471
                     /locus_tag="ACF3UE_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635220.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(1544..2191)
                     /locus_tag="ACF3UE_001826"
     CDS             complement(1544..2191)
                     /locus_tag="ACF3UE_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3635221.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(2199..2885)
                     /locus_tag="ACF3UE_001827"
     CDS             complement(2199..2885)
                     /locus_tag="ACF3UE_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635222.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(2891..3964)
                     /locus_tag="ACF3UE_001828"
     CDS             complement(2891..3964)
                     /locus_tag="ACF3UE_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3635223.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            4186..4860
                     /locus_tag="ACF3UE_001829"
     CDS             4186..4860
                     /locus_tag="ACF3UE_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3635224.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            4865..6205
                     /locus_tag="ACF3UE_001830"
     CDS             4865..6205
                     /locus_tag="ACF3UE_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFD3635225.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(6354..7340)
                     /locus_tag="ACF3UE_001831"
     CDS             complement(6354..7340)
                     /locus_tag="ACF3UE_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HFD3635226.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            8064..9095
                     /locus_tag="ACF3UE_001832"
     CDS             8064..9095
                     /locus_tag="ACF3UE_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3635227.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            9204..10736
                     /locus_tag="ACF3UE_001833"
     CDS             9204..10736
                     /locus_tag="ACF3UE_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFD3635228.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            10875..11687
                     /locus_tag="ACF3UE_001834"
     CDS             10875..11687
                     /locus_tag="ACF3UE_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFD3635229.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            11677..12162
                     /locus_tag="ACF3UE_001835"
     CDS             11677..12162
                     /locus_tag="ACF3UE_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFD3635230.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            12185..12730
                     /locus_tag="ACF3UE_001836"
     CDS             12185..12730
                     /locus_tag="ACF3UE_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFD3635231.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(12803..14446)
                     /locus_tag="ACF3UE_001837"
     CDS             complement(12803..14446)
                     /locus_tag="ACF3UE_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFD3635232.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(14575..16803)
                     /locus_tag="ACF3UE_001838"
     CDS             complement(14575..16803)
                     /locus_tag="ACF3UE_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3635233.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(16836..17315)
                     /locus_tag="ACF3UE_001839"
     CDS             complement(16836..17315)
                     /locus_tag="ACF3UE_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFD3635234.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT         5246 a         3300 c         3162 g         5807 t
ORIGIN      
        1 ttaatgagcg tttcattgaa agaaaagggt tgagggagaa aaacatatga tcaggttgtt
       61 ggaattaaac tatagaaaga tggaaaaaat cattcgaatt ctgtccattt ctgacaagtg
      121 gatgactaaa aaagaacttg ccaaacgaat tggtagttca gaatctacat ttgtaaggta
      181 tatcgaagag atcaaaatcc gctggggaac ggatgtaacg attcaatctt cacaaaaatt
      241 ggggtatcgt cttgaacatt tgaatgtacc agcttattta aatgttctga tggaaatgtc
      301 gcaaagttct acaaacagtc gtttattaaa tgagattatt gtcaatccgg gtaaaacgat
      361 tgagtattat tgtgaaaaaa tttccatcag ccggtcttct tttacacgta agttgaaaca
      421 atgcaatcaa attttagaaa gctatttatt aaaagtgatc gttgaccaag gttttcagtt
      481 aactagcctt aaaagtgagc tccagttgcg tatctttgtt acctttttct ttttaagtta
      541 ctacggaaga cgcacgttgc catttccaat cgaaaaaaag aagatcaaag aaattatggt
      601 caagaataat tgtcagatga atttgtttca ggaagaaagc ccatatgagc aatctttctt
      661 tattatgtat tttgttgtgc atctcatgag agaatcccaa ggaactccat ttgaatggaa
      721 agctggagac tcttatgtac agttgataaa tatcgataaa aaagacttct taatcttgaa
      781 aaatctctta ggaaaattga agtacagcag ctatataaaa gtagtgaact attttgtcaa
      841 tacgattttt tcagaatttt cggagaaaga aaaaaatgaa atcagtgagc agatacgaaa
      901 aaatatgtcc tactgttcgt tttcatccgc tgattgcaaa gaaaaaaacg aagaatatgt
      961 tgttcaatta ttaacgcaaa tttatttttt ctcccgtatt ttcccatacg atacgactca
     1021 tttgacgatc cgtgcaactt actttgcaca gcagatgcaa caccgccaga tacgtctata
     1081 tgctggattt cgtgcagaac ttcaatttta ttccactcta ctgaatcaga atctgattta
     1141 ttatttatct agctatatct tttggatgct tatcggtaat cctgaaattc accattatac
     1201 ttctgataaa aaaatactga ttatcagcga cttaagtctt cgacatagtc aatatattga
     1261 agaatatatc agtgatattc ttgctgtgca taaaattcac tctgagacaa ctgctattac
     1321 tgaagatcag ctgtcgaaat acaatcttct cgagtatgat ctgatcgtta cgaatcaacc
     1381 cattttgaat gcccatgttc ctcatatatt gattgatgat agtgtgtcat tcgcaaatga
     1441 agaagaactc atccgcttat tcgagttatg aataatcaaa aaacagctat gtataaacca
     1501 ccctgataaa aatttcagga caaatacaca tagctgtttc tttttattgt attccttcag
     1561 caatccaacg agatttatag cgaaagtctt ttaacaactc ttcttttgtc caattatttg
     1621 caatgagatc cgtcaaagtg ttcattacga gggtcatgga aaagtatagg aaactaactg
     1681 cttcttccga cgattgaatg gagaaatgat tgattcttaa taattccagc catttttcgt
     1741 tcattggaga atcagccgat agttctctac gtttggttgt ctgctgatca tttcgctggg
     1801 ttaacaagta taacctttgc caatagatac tttcgtgatc taagtcgcag caccactcta
     1861 aatatttttc gatccccaaa aagaaatgtt gtttgttttc gctaatgaat tttaagatat
     1921 cttgatggac tatgtgagaa ctgcttttga tcgtatacaa ataagcatct tccaaatctt
     1981 gaaaatattt ataaaaagca ccgcgcgaca tccccatctt gtcaacgatt tctgagactt
     2041 tgacttggct gatgtgctgt gagcaaaata tctccagtaa taggtcatcg attctctgtt
     2101 tctttgcgtt cgataaattg aaaaaagttt cttttggcat ccacatctct cctttatctc
     2161 tgattatacg tggatagccc ttcattgtca tgaaggattc attccttctt tttctcttct
     2221 tctgtcaagt acccatcttc cattcgataa acgcgatcac tccattgaat catacggaca
     2281 tcatgagtaa ccataatagt cgctttttgt ttctcatgag cttctttaac tagtaatttg
     2341 acgacttcat atgcatgatc tgtatccaaa ctagctgttg gttcgtctgc taagatcaag
     2401 cttggctcat tatataaagc gcgagcaatt gccactctct gtctttctcc accagaaagg
     2461 tctttaggat aactattttt aagtgactgg atatctaaag attgcagcaa ggaatcgatt
     2521 tttgttgaat cttctttttt tgaagtaact tggtcaacta gttcaaattg ttcctttacc
     2581 gttaaaaaag gaatcaaatt agagctttgg agaataaatc ctatttcttt aaagcgtaaa
     2641 tctgctcgtt ttttttctgg aagctcagtt agtgagtgac cgttgatcac tatttctccg
     2701 gaagtcggtg tttgcaatcc tcctgaaatg gtaaggaaag tacttttacc tgaaccagaa
     2761 ggaccaatga tgctgacgaa ttctccttcc tttacataaa aatcaattgc tttcaaagct
     2821 gagacctttg tatgaccaga accaaatgtt ttggtaactt ttttcatcgt taatattttt
     2881 ttcattttta ttaacctcct attgctgtaa ttgggtctac tttggttatc gtacgtatcg
     2941 aaaacaatcc gcctagcatt gcgacaatga tcaaaatccc actatatagc aaccattgtg
     3001 accaaaaaac agcaaaaggc atcgcgcttg gtaaaatcag actagtcaaa taagcaaaca
     3061 aaagagcaag cagaacgcct accaccccaa caataaagga ctgtgctact aaagatttag
     3121 cgatgaagaa atttttgatc ccttgtgctt tcattactcc aaaaatagca gtcttctgaa
     3181 gtgtcatcac gtacatgaaa ataccgacca cggcagcaac cactaagaac aaaaagtata
     3241 tcatcgcatt taaggtcata ttttgggcag aatagccagg aatactttca atgaatgtcc
     3301 caatagttaa taactgtaga cccttcgatg ctttttcttt cgaaatttta gctgaatcct
     3361 ttattacgat cccattgatc ggctgttctt cttcagaagc aaacggctgt tgtccatact
     3421 tcaaagcagt ccacgtatct agggacgcat agatgacggg agaaactgtg taataagttt
     3481 caggaaagat accgacaatc gtcaaaggat cgtcgtaact gccaattttg atcgtatctc
     3541 caattttata gcctgaatca gccagatttt gagagatgat gatttcattc tttgttttaa
     3601 attcatgccc tttcgtgagt tttggtaata aaaatgcttc tttcgttgtg ccgaaaactg
     3661 taacattttc tttgtttttt cctttgattg ctccgctgta caatccgatt ggtgctttct
     3721 ctcctccttc aatgtatttc agatctcctc ttgttaattg tgaagctgca aatacttgat
     3781 ttgcatcctc cgacaaaaca atctcttgtg cgtcccaatc atcgattgct tttttaaact
     3841 cttctgaaag tccattcgct agtcctgaca acatgaatac gacatacgca atcaagaaca
     3901 taataccgac gatcaagcca tatcgtaatt tagaatagcg aatttctttg atagctagaa
     3961 acatttgttt ttcctcccta tgatagattg atagtgacaa aatgtcactt gttgaatagt
     4021 gtaactctaa agtgacaatt tgtcacttgt gttgtttttt tcttatcaat aaattgtcta
     4081 agacatcttt cgataaaacc ttaacatgag tcataaaaaa tttatttaag ccttatttat
     4141 gctttccatg ataaactaaa gtgaccaaat caatgaggtg ggaaaatgat taaactatta
     4201 gtagtagaag acgataaagt attatccaat aatataaaag aaatactcgc tgcaatcggc
     4261 gagataacac aagtttatga tggtagtgaa ggactgttcg agttggaaag tggagtttat
     4321 gatcttgcaa tcttggattt gatgatgccg gaaatgaatg gatatgaagt gttagcaaaa
     4381 atacggaaag aaaaaataca gactccagta ttgattttga ctgcaaaaga tagtttggaa
     4441 gataagattg aaggatttga acgaggtgca gatgattatc taacaaaacc tttctatcga
     4501 gaagaactga tcatgcgcgt gaaagcatta ttgaaacgct cgctaggtct ctttgatgaa
     4561 aatgttctga agtataagga tatcagttgt gatttaaaaa gcaatgaagt cttgtataaa
     4621 gaacaagttt tgcccataca aggaaaagag tttgaattgc tcgtttattt tttacaaaat
     4681 aagggaatca ttttgacaaa agagcagata tttgaccgga tctggggatt tgattctgat
     4741 acgacgatta cagttattga agtttatatg agcaacttac gaaaacatct gcgaagtact
     4801 ggattggata aagaaatcaa aaccttacgt aatgtcggtt atatactgca aagggtgtga
     4861 tgcaatgaat ggagatatta cacgaaagca acgtagtcgc ttttttgcga caaatgtagc
     4921 agcatttgct tttatctttt ttcttttggg attcattact ttacagatat taaaccaatc
     4981 tgcatacaga gaaacagatc tgtcattaga gaaaataaat tttgattctc gaacagtaca
     5041 attagagata caaagatatc agcaaggcga tcccttttta aacccgactc aaacggaaca
     5101 aaacagaaca aacatggaac agccattaat ggaaccatca aatgaccgtt ttaacactca
     5161 agtgatcttg tggtctaaaa atggtgagat attgaataaa gcagctattg gtgggcgttt
     5221 caaccaaatc aaagaattaa aaatggatac gaaaaatctg aataccatcc aaaatattga
     5281 attaaatgaa gacagtggct catctgccct ctctttccgt tcgattacga aaaaagcgga
     5341 gacgaatcaa gatggcgttg cctacatcca aattttagaa aatacaaatc aaatcaagaa
     5401 ttcattagcg acttttcgca cgattatgat tttgtgtatg attgtttttt ggattctctc
     5461 tattggtatc agttattact tgtctagtct aagcatgcgc cctattattc tttcttggag
     5521 aagacaaaaa gaatttgttg agaatgcttc tcatgaattg cgcacaccgt taacgattat
     5581 tcaaaatagt ttggaacatc tttttaccaa gcctaatcat actattattg aagaatccga
     5641 aagcatcgct caagcattgt cagagacgag gcgcctcact ggattgactt cggatttgct
     5701 gacaatcgct cggaatgatt ctgatcagca gctgctttca aagcaaatga tcaatacaca
     5761 agaatatatc gaacaacttg ttaaaccatt tcaagagatg gccatcatag atggaaaaga
     5821 gtttattctc cataacgatg caacattaga agtaccaatt gatgaaaaaa aaatccatca
     5881 agttttggtt attttgctgg ataatgcatt aaaatatacg aatccagaag ataagatcat
     5941 tttggattca tctgttaacc ataaagaatg gctgattcac gtaaagaata ctggcccttc
     6001 tatcagtgaa gaagatcaag caaggatttt tgatcgattt tatcgggaag atcaatctcg
     6061 ggcgaaagag actggcggat acgggcttgg cttggcaatt gcaaaacagg taatcgaaca
     6121 gcatcatgga cagatttctg tatccaatta tcttccacaa ggagtcgatt ttaaagtcca
     6181 attgccgttg aagcctaaaa aataatgctt atccctaaaa aagggctgtg acaaaaatct
     6241 tgtcacagcc cttttttgtt gcgaataaac ggtgttccag aagtagcttc ttcggaaata
     6301 agccgaaatt tctttaagct gaccacttct gtcacaacct ctttagctta cgcttacgat
     6361 tttttattgc ggtcttcaat gtgtacatca ccgcttgtgt caatatccaa ttcttctcgg
     6421 ctaacatctt ctgtcacttt ttcaacatct tcatgttctt ctttatgaat cccaacttct
     6481 tcacgaataa ctgtatgttt gcttacatct acttgctctt ctttgattgg gatagtaatc
     6541 gtgtcatctt ccaatttttc gtctgttccc tgtgaagatt gatctgttac tggtttgcgt
     6601 tcgatgacga tttcttcacg tttgaccggt acttctaccg tttcagtatc gttgaccaca
     6661 tgtttgtgga tgtcgacttc tccagttgtc acatcatgtg tatttacatc taatttttct
     6721 tcttttagtt gaattgtatc atcatctaga tttggtttgc gatcgatgtc ttcagtcttg
     6781 cttgtaccca ttgtatcagt ctcgccaggt acgtccatcg gatcagttcc tggtgtcata
     6841 ttcaatggat ccgttgtatt ttgaaagcct gtcgtgccac ctacgtccat tggatctgtt
     6901 ccagtgccag tttctaatcc agtccccatt gtgcttgctg ggctaacagt atcttgtgta
     6961 tccattgtat cttctgttgt ttctggctga cgatagcctt ttactgtgat gacaaatttt
     7021 ccatcagaaa tatctcctct atattgatat aaaggatcat tttctggtgt agccgtctca
     7081 gaatcatagg tatcaaaaga aaaagtatct tttatttttt cccataaaga acggtcttct
     7141 tcaccatcca tccgattttc atctgtttca acatctatac cagacaatcc gtcaaatcct
     7201 agtctagatg ctgcttcatc agtagtataa ataacgatat catctcgttc atacccttcg
     7261 ttacgcaacc gttcaattac tgataatgct tcttccctcg tactatagct tccgatgacc
     7321 gttaaatttt tctcttccat gtaaattcct cctagcaaat agatttatga ttggtatatt
     7381 gttacttata aatttattct ataggagacg attgttttct acaaatattt agattggaat
     7441 ttgattaaaa caatttaatt gaaatttgaa aacatttatg ttaatgaaag tcatattcta
     7501 ataaaatgtc atttgtttct atatgaattt ttatgaaaaa tttcatataa tttccactcg
     7561 ttgtgatggt ttaatttatc caatccatca ataagcaaac aacttatata aaaaaggatt
     7621 aattctcaat ataattgctc ctaccataga ataaatcttc atgtaaagta atgaagtacc
     7681 aactatttct aatacttctt taagaattat cccaacaata tcgttagaca aaccattatt
     7741 gaataaatgg agagccaatc gattctgaaa aaatgttttc taatttttcg gaaataaaag
     7801 aaagagcctc ctgccattag aacgaaccaa atccatttca ttgctcatga agtaaccaca
     7861 tagctaaaaa gaggataaat caattaaaag atcaaaagaa tgactgcact aataaaataa
     7921 ctaaaaatgt atcttcttac ttcatatctt ttagctagta cttagttaaa aatttgcttc
     7981 ctaagatcaa gacaaactgt ctatcttcat ttgatgaaat gcggtaaaat atagaaaatg
     8041 aacactattg gagggaattt gtaatggaca gcaaaactag aaaacaactg caagaaaagt
     8101 taaagcaacg tacacacttg ctcccttccg tctttcaaca gtttttagaa gaaaatcgtt
     8161 cttccctttc attaggcagt cgctatgaat acgcaaaaga ttttcatctg tttactgatt
     8221 atttgagaaa agtattttct gaagaagtgg atgatcagct gattatccat ttagaaaaac
     8281 aagattatca gaatttctta gctaaaatct atcgacatac tcgttcgttc caaactacag
     8341 cgaaccaaga aacggagcaa ttgtttgaaa atagctatta cgggatttca aggaagcaat
     8401 attcattaaa tcatttttta cgatttttgt atcaaaaagg actgattgaa gaagagattt
     8461 ctcttttggg tacaagttta ccggaaacaa ccaaagcagc tccgcgatat atcgatgcag
     8521 aacttttcaa agattttgag catttgttta tcccgattga aggctttcaa acaagcagag
     8581 aagctagctt tgaagaaaag aatagaccga ggaaccttgc aattactgcc attcttctgt
     8641 attgcggatt aaagatccat gaagtagtag aacttaaacg taaagatgta tctttgacca
     8701 agcagattct taatctgaat agaaaagaaa acagactgaa taaagtacca ataccaaaag
     8761 aagcgatgcc atttctggag aactatttta agttaacagc acaaaatacg gacgaaaatt
     8821 cttttgtttt tcgttcctca catgatcagc aaatttctcc tcggactatt cgccaaattt
     8881 tgagcaaaat tacagtatat aaaaacgtat cgccagaact atgcagaaaa acatatcgtt
     8941 attatgcaga actatattta gatgatgctg acgcggtaaa ttatttatgt ggtaatcgat
     9001 acctctcatc ccattctttt caagatatct gggaaaagat ggttgatttt tcttatcacg
     9061 aattagcggc attcgttcgg gtttcttcca tataaaacaa atgtatgatc tttttttcac
     9121 aataaactat gttattatat aaaggattat gttacgatta tcttgaattt gtatattact
     9181 taacaaaaga taatggagtg tgaatgatgg agaccataac gtattcccct ttgaacttat
     9241 ttacgaattt tcaagaagct gcagctaact tttccgagac cccgattatc tttgatgagc
     9301 cactttcagc tttcccagaa ttaggacttg aaacaactta caaaaaatgc tgcgaaagtg
     9361 tgttgaaacg ggcttatcaa ttggctcatc ttggagtgaa atccggagac aaagttatta
     9421 tttataagag ttccgctttt gacacatacc ttctagctgt ttctgtgtct taccttggtg
     9481 cagtgcctgt catgacttct tatcatctac caacaacaac aatggaagta tttatcgatc
     9541 gtttagaaga ccctttcatt ttatttgatg atgagacaaa aaagcgagtg agagaaattt
     9601 caaatggaac aaaatcaaaa cagattccta ttctttattt aatggaacaa cctgctttgt
     9661 ctgtttctca atcattttta gacaaaaatg aaatttctta tatgacccat acttctggta
     9721 caactggtat ccctaaactt atttgtcatt ctgctcattc tatgggatgg cggacgaaat
     9781 ggcaaaaaac agttttcaca aaaatttcgg aaaagaaatt aatcgctttt cacatctctc
     9841 cagtgcattc cagattcaat attggtatct cttctttgat gtccatggga tttcctatga
     9901 tgcctttagc aaacgcacaa agttcaaaag ttgttcatat gttggaagct caccggccaa
     9961 ttgcactaga gacccatccg aataactttg ttcagtggcg ttttactgct aaggagcatc
    10021 cagaagcttt ttcgggtatc cgatactatc actccacttt tgatgctata aacaaccaga
    10081 caatgaagac atttttgcga acgtcgatgg cacaggatgc ggtatttctt caagtatatg
    10141 gccaaagtga atgcggacca atgattctta aggctcatac actagagagt ttgaaaacaa
    10201 gtgatgcaag agatatgggc gttggactgg aagacatgac aagcgctcgg attacagatt
    10261 cagttgggaa tgtcctacct gaaaacacag atggtcatat acaattactg tctaaaggac
    10321 gggctttgac ttattacaag gaagatgcac ggttccagga aaatgtttat ggcgattggt
    10381 gggatagcgg agattacggt tttatggata agcatggcca cctatttttg aaagatcggc
    10441 aagtggattt gatcgaaacg atcaatagta cattagctat tgaagacttt ttattagatt
    10501 cgttagattt tttggcagaa gtagtgattg taagggataa aaatcattct ccacaaccga
    10561 ttattgcttt agctcctgat aaagaaatgg attggaatcg atggtgggag caagtccatg
    10621 aacttcctcg cttgaacgtc cctatcatcc gtgattttga tgcaatcccg cgaacagcta
    10681 caatgaaagt gcaacggctt caaatcgaga aagaattaaa atcacaaaag tcctaactat
    10741 ttaaggaaag aaagatccat tttggtcttt cttttctttt tgttttttta aattggatga
    10801 gataaaaata tgccaattgg ctgtttttct tttttgaaaa tttcgttata ctcttattca
    10861 tggaggaaaa tgttatgaaa agaatcttga caattggcgg ttctgatcca tttgctggtg
    10921 gaggaatcca aacagattta aaaacttttg agaattttgg tctattcgga ctaagcgcct
    10981 tgacttctat aggggcacta gatattaatg agcgatttat gctggaatct atatctttgg
    11041 aattgcttaa acgacagtta gtttcgattg ataaaatgac ttcattagat ggtatcaaaa
    11101 ttgggttatt gaattcaagt gaagcaatca tggttgttcg agacttcata aaaacaaaac
    11161 aaaatatccc aatcatttta gaccctgttt tggcattcaa agaaactgaa gctgtgatca
    11221 atcaattgta tatttcgcag ctcatcgaag aactttttcc acttgttacg atgattacgc
    11281 ctaatttggc agaagctgct ttactttctg gtcaagctct tccctcttcg ttaacagaaa
    11341 tgatccatct cgctaaagaa ctcactgctt caggaacaaa aaacattgtg atcaaaggcg
    11401 gcacaaggat ggctggagat gaagctgtgg atcttctcta ttcaattgat cattatgagg
    11461 tattttctca taaaaaaatc gacactacaa cagtaaacgg ggccggttgt gccttttctt
    11521 ctgcaataac agcgaatctt gtgttagggg cagattttac caaagcagta gcagaaagta
    11581 aaaaatttgt tgcccattgt atttctaatg gcgtgctgat gaacgatcat accggaagtg
    11641 tctggtctgg cggtattcaa aaaggaggaa tgagaaatga aaactaagca attaacgatc
    11701 tatgctatgc tgattgcgtt gacagttgcc ctttcattaa caattttgat ccctgtaccg
    11761 gctacgaatg gatttgtgac attatgcgag gccgggatct ataccgctgc ttttctttat
    11821 ggtccaacgg gtggattagt tgttggtgct tccagtggtc tattgatcga tttgatttca
    11881 ggatatccgc agtgggcagt tttttcatta gtgatccacg ggttacaagg atatgttgct
    11941 ggttctttca gcaaatcttc tactcgtatg tggggattag ggcttttatt aggaagctta
    12001 gttatgatca tcggctatgg tatcgccggt tggattttat atgattggcc ggctggagtg
    12061 gcttctatac caggaaacat cttccaaaat ctgattggaa tgggacttgc ctttcctata
    12121 actgcaagtc ttcaacgtat tcaagcacgg aagcaatatt aattgaaaaa gaaggtttta
    12181 gaaaatgaag ttgtcagaaa aagaattaaa agaccaattg actgaaatag ttaatgacat
    12241 attggctgag gcacacttga aaaaaggtga tctttttgtt ttaggatgca gcacaagcga
    12301 agtcgttgga ggacatattg gaaaaaattc cagtgcggaa gttggtcaat ggatcatccg
    12361 tacgttaaaa gagttgttgg atcctaaaga aattgcgcta gctgtccaag gttgtgaaca
    12421 tttgaaccga gcattagtag tagaacgaac agtggcagaa gcaaaaaatt tcgaaattgt
    12481 ctctgttgtt cctgcactac atgctggagg tgcttgttct gttgctgctt ttgaccagtt
    12541 caatgatcct gtcgaagtgg aacacgtagt tggacaagcc ggtatcgata tcggtgacac
    12601 atcaatcggt atgcatatca agcatgtcca agtacctgtc agacctcgtt tgaaaaccct
    12661 tggacaagct cacgtgacag cccttcgctc tcgtcctaaa tatatcggtg gtcctagagc
    12721 gaattattga aatgagtaat tgacagagca atctgaaaaa cttcctcgca aagtccaact
    12781 aatgaacttt aacgaggaag ttttacttgt ttgttttata taaccgagct tcataaggtg
    12841 ctagtatgcc tttagcttca aattctccgc tagaggaatt tgacaagagt aatgtccagg
    12901 actgatctgc ttcttttgga agttcatagt cagcaagtga ttctgttaag tttaccataa
    12961 taagatattg ttcatcttct aaatatcttt catagacata aagttgtgga tgttcatgaa
    13021 gatattcttt ataagaaccg tatatcagac ctttattggt ttgtctaatg cggatcatgt
    13081 tcttatagaa ttgcaggacc gactctggtt catattcttg ttgttctaca ttgatcgttt
    13141 tggtatttgg attagtgatc agccaaggtt catgtgtaga aaaaccagca tattgttccg
    13201 aagtccattg catgggtgtc ctgctgttgt ctctcgttgt ttcacgaatg atatccaatg
    13261 cttcttctct tgtcttacct tccgcaagca gccttttata aagtcttttc gaatctactg
    13321 catcaacttg atcgatcgat tcaaagggca tattcgtcat tccgatttcc tgtccttgat
    13381 aaataaatgg cgtaccttgc aaaaagaaat acatcatagc gattgctttt gcagacatag
    13441 cccaaaaatc gggacgagta tctccaaaca ctgaaacggc acgaggaaca tcatggtttt
    13501 ccatatataa agcgttccat ccgataccat ccaatgaagt ttgccaagcg cttaatgcat
    13561 gtttcaattt aaggacatct aattgccctt ctttttcttg ctgccagata tggatatgat
    13621 caaattcgaa tatcatatcg aaataaccgt ctttccctac ccattgtggt ccttcttctg
    13681 cagtgacacc acttgcttct ccgacagtca tgatatcgta ctcttcaaaa acatgtttca
    13741 aatcggtcaa atgttcttcg attcctgaga cattttgaaa gggtgagaaa gggttctctg
    13801 tggcttttac tgaatattca tcttttttta catgagaaat cgcatctaaa cgaaatccat
    13861 ctatcccttt atccaaccac catcggatca tattgaatag ttcttctttc aatttctcgc
    13921 tttcccaatt taagtctggt tgttcttttg caaaaacatg cagataatac tgtccagttt
    13981 catgagaata ctcccaagca gaaccgccga aaatcgatgt ccaattattc ggttctttgc
    14041 catctacccc gtcgacccaa atgtaataat cgcgatacgg gctttcttta gattttttcg
    14101 attcttcaaa ccattgatgc tgatccgaac tatggttgat gacaagatcc ataatcactt
    14161 tgatccctaa ttcatgtgct tcttttagca ataaatcaaa atcttccatc gttccgaatc
    14221 tctcttctat atcttgatag tcacttacgt cataaccatt atcgacaaat ggagattgat
    14281 agatcggatt gatccagata aagccgatac caagatcttt caaataatta agtttttcac
    14341 ggatcccatt gatgtctcct tgaccatcgc cattgctatc tttgaaacta gcaggataga
    14401 tttgatagcc tactgcttct ttccaccatt tttgttcttg tatcatatcg tttcactcct
    14461 ttaacggtcc ctcttgatta taaccgattc tattttagaa gtatccttgt taccggtaac
    14521 tagaaacgaa aagctcaacg aatctgctaa gtgcgttcgt tgagctttat tttatcatag
    14581 atagcgggca atcagttgaa tcatttgctt gggaaattca ttcaagtcag taatatctac
    14641 aaaacgactt tcaccgtaga tcgacttgat ttcttctttg tcttggccaa tagctgcgga
    14701 gacaaatagg attccttgac gttcatattc tttcaaaaca gactggatat cttcttttgc
    14761 ttttttgcct gtataatccg gcaacgcttt tggctgaccg tcactaatat taagcaacag
    14821 tttggttgtt gcggattgtc tgtttaattt ttctgctgct aaacgaagtg cagcaccatc
    14881 acgattgttt tgccttggtt tcatagtgac taatttttca tttaaccatt gaaatccgtc
    14941 ttcaaattct ttataagaaa acaaagaagt cttttctctt gacgaacggt ctgctgtatc
    15001 tccgtaaatc aacaatggga tatcgacttt cttagaaaat tcggcaatgg caatcgctgc
    15061 tttttttgcc gcttcgatcc gatcatcccg tatcattgac ccagattcat cgatccgtac
    15121 agctaccgct aaagaaggtt gctcatgtgg cgggttcttt ttgtcaaaat ttctcaaatc
    15181 accatatgct actttgcttg cattgaaccg ctgaccttcg tattttcctt tttggtacgt
    15241 ctctgtttgt tcattatcca gtaactctaa aatttgccgg ctaagtgatt ctactattgg
    15301 cattacttgc atgtgtagct cacgtgcttc cggcgttttt ccttggaaag ctggtcggtg
    15361 aacgatgaga ccttcttttt catgaatcgt ttccttcatg atttgtcgcg cttctttatt
    15421 cagttgcttc ttgatttcct tatcatgtgc ttccatgtca gaagcagaca tttcttgaga
    15481 atcatctcct gtttgttgtt ctttttgatt ttttccttcg atatcgctac tgcgttcttt
    15541 ttgcatttga ggaggaatct cgtttttttc tattgtttct tcttgtttct cttctccctc
    15601 atttggttct tcagcagaca acgatttctt ttcatctaag cgcagaattt cttcagcatt
    15661 ttcagtgatg tttcgttcat ttgcttcttc ggcgctaatg gttctttctt ttgtatgctc
    15721 agattgagga tgaccccatt tttcttttct caatatgtcc tgaagttcca gtagcaatcc
    15781 actgtcagac aaagcttgtt caagaattgc caattcatct gaatcagtgg ataatttata
    15841 caaaactttt ggataaatcg actggagtaa atcttgtcct tgcttatagg tatttgccca
    15901 ataaaaataa gaacgcattc ctgctacacc tttgatggcg ttagcttttg cagtttcatc
    15961 caacaaacgg ataatctctg ccatctttaa gagaagttct tgtttttgga tcatagtttt
    16021 cgccatcgca cgttctgcca tgacttctaa ggcaggaaga tccatttttt ccgcatgttg
    16081 catccgatct cttaaagatt catttaatgg gcgatttcct tggtaatttc gatttgtagt
    16141 gatcacaatg acgcaatctg gatggcgacg aatgattcct gtcggtaaat tcaacatccc
    16201 atttggttcg agcgctgagt taagtgccac aagaacagag gcatctcgga tgacagtcgg
    16261 ctcttgaatc tctaataaat agcctttttc aatcgctcga acgatttcag aagggtaata
    16321 gctgtaatgg attgcatctg gataatcagc ttcgatcctt tgaactagct ctgctaattt
    16381 ttctttagca gaaaaaggat caatgccgta atggttctgg atcagtgtca gtacagcttc
    16441 aagtgtatct gtttggtaaa tagcttctag taattcttgg tcttgttcct tattagaatc
    16501 tactacaggt aataaggctc cgaaaacatc tgatttgtcc atatctgcaa aacaggtcac
    16561 ttttgtatag ggaagttgca gatcagcaga tagtgctttg gctaattgtg tcttccccga
    16621 cccggcatct ccttccaaaa gtacgttact gattttcatt tcaggatctt gccaattccc
    16681 tttgatttcg gaggcgatcc gccattcttc tgcacttgtc cgatggcttt tcggtttctt
    16741 ccagatcatt tgcttttcta gccgtgaaaa ggttcggttt tctgttagtg agaaattctc
    16801 catgcttctc ttcccctttt gatcatctct gtctattaat atcctagctc atctaaaaga
    16861 cgttttaaaa tacggaatcg ttccccaatc agttctccgt ctttttgtag tgtatcgtaa
    16921 tacaaaatga tgtcttcatc gatctttgga tttttggtat ctacttctac cgtcattcgg
    16981 ttcccttgta atccaatgat gtctacgact ggattttctg gatcataaaa tttttcataa
    17041 cgataagcat cttggaagta taaacttcct tgcgcagcta agatcgctaa atctaaaata
    17101 cgtgtgattg gtaattcttc cgactgtcgt gaccattttt ctccagtatg tcgccatacc
    17161 ttgcctgaga tatcgacttt tccacgatca ttccactgag caaggcccag tgaaagccct
    17221 tttgcatcca tatttaatgc atttcttcca tcaactttat catagtcttc tacaacgatt
    17281 actggtttat gttttaaatt tgttggtatt tccattattt taactcctca tccttttatt
    17341 tttagtaaat aagtaaatta gtagtttact catttactaa actatatgcg acattataga
    17401 ggattgaagt gaggattgca aagaaaaaga gcttcattga tagaaataaa aacaccatct
    17461 cgttctttta cacgctcatt agtaacatgt agaaagtcca agatgatgtt ggaat
//
LOCUS       DAXLPC010000058        17195 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.058, whole genome shotgun sequence.
ACCESSION   DAXLPC010000058 DAXLPC010000000
VERSION     DAXLPC010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.058"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            52..933
                     /locus_tag="ACF3UE_001840"
     CDS             52..933
                     /locus_tag="ACF3UE_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3635235.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            936..1706
                     /locus_tag="ACF3UE_001841"
     CDS             936..1706
                     /locus_tag="ACF3UE_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635236.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            1985..2839
                     /gene="aroE"
                     /locus_tag="ACF3UE_001842"
     CDS             1985..2839
                     /gene="aroE"
                     /locus_tag="ACF3UE_001842"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFD3635237.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            3017..4180
                     /locus_tag="ACF3UE_001843"
     CDS             3017..4180
                     /locus_tag="ACF3UE_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFD3635238.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            4297..4707
                     /locus_tag="ACF3UE_001844"
     CDS             4297..4707
                     /locus_tag="ACF3UE_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFD3635239.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            4881..7109
                     /gene="topB"
                     /locus_tag="ACF3UE_001845"
     CDS             4881..7109
                     /gene="topB"
                     /locus_tag="ACF3UE_001845"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFD3635240.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            7280..7564
                     /locus_tag="ACF3UE_001846"
     CDS             7280..7564
                     /locus_tag="ACF3UE_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635241.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            7724..7960
                     /locus_tag="ACF3UE_001847"
     CDS             7724..7960
                     /locus_tag="ACF3UE_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFD3635242.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            7957..8356
                     /locus_tag="ACF3UE_001848"
                     /pseudo
     CDS             7957..8356
                     /locus_tag="ACF3UE_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
     gene            complement(9023..9967)
                     /locus_tag="ACF3UE_001849"
     CDS             complement(9023..9967)
                     /locus_tag="ACF3UE_001849"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFD3635243.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(10263..11207)
                     /locus_tag="ACF3UE_001850"
     CDS             complement(10263..11207)
                     /locus_tag="ACF3UE_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFD3635244.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            11428..12642
                     /locus_tag="ACF3UE_001851"
     CDS             11428..12642
                     /locus_tag="ACF3UE_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3635245.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            12664..14679
                     /locus_tag="ACF3UE_001852"
     CDS             12664..14679
                     /locus_tag="ACF3UE_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HFD3635246.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(14762..16135)
                     /locus_tag="ACF3UE_001853"
     CDS             complement(14762..16135)
                     /locus_tag="ACF3UE_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFD3635247.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(16211..17170)
                     /locus_tag="ACF3UE_001854"
     CDS             complement(16211..17170)
                     /locus_tag="ACF3UE_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3635248.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
BASE COUNT         5633 a         3042 c         3352 g         5168 t
ORIGIN      
        1 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
       61 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
      121 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
      181 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
      241 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
      301 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
      361 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
      421 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
      481 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
      541 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
      601 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
      661 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
      721 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
      781 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
      841 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
      901 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
      961 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     1021 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     1081 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     1141 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     1201 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     1261 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     1321 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     1381 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     1441 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     1501 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     1561 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     1621 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     1681 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     1741 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     1801 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     1861 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     1921 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     1981 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     2041 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     2101 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     2161 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     2221 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     2281 tttgattggc tataatactg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     2341 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     2401 tgttcaagca gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     2461 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     2521 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     2581 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     2641 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     2701 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     2761 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     2821 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     2881 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     2941 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     3001 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     3061 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     3121 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     3181 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     3241 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     3301 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     3361 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     3421 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     3481 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     3541 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     3601 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     3661 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     3721 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     3781 tctggatggt gtagatatta aaaaaggggg ccagaagatg gatggacatg ttcttttgca
     3841 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     3901 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     3961 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     4021 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     4081 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     4141 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     4201 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     4261 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     4321 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     4381 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     4441 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     4501 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     4561 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     4621 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     4681 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     4741 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     4801 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     4861 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     4921 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     4981 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     5041 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     5101 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     5161 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     5221 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     5281 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     5341 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     5401 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     5461 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     5521 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     5581 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     5641 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     5701 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     5761 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     5821 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     5881 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     5941 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     6001 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     6061 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     6121 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     6181 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     6241 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     6301 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     6361 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     6421 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     6481 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     6541 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     6601 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     6661 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     6721 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     6781 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     6841 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     6901 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     6961 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     7021 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     7081 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     7141 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     7201 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     7261 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     7321 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     7381 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     7441 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     7501 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     7561 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     7621 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     7681 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     7741 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     7801 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     7861 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
     7921 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
     7981 attatcaaaa tcaacgcgaa agttatttta ccgtcactcg ccaggcgaaa tgatcggtgt
     8041 aaaagatgca aatgcattag atatggccgt caaacagcct tcacaagcag tattcaatca
     8101 agaactctat cctgaaatct atgaaaaagc ggcgatttta gcaattaatt tagctaaaaa
     8161 acatcctttt cataatggca ataaacgaac tgctcttgtt gccatgttgt tgtttcttca
     8221 attgaataat tgtccagttg ctttttctcg tcaagaagct gttgatttta tcataatgat
     8281 taccactagt tcattggatt tcgattcact aaagtccaag ataaccagtt atttacgaca
     8341 aaccgcaata aaatgaacga attaaaaact ttatttctca attagatcag catgtcatta
     8401 aggaatatgc tgattttttt atgtttaatc atacaaaata gttttttcat aaaaatatgg
     8461 aaaatatgga ttaattttga aataattgat ttaaaaggaa tacaaaagag tgaatagtag
     8521 gaaatagtgg tttagaacta gtgggctgat tttttatata ttttagttta cataatatat
     8581 attatacaaa gtagatttaa aaaatgataa acctctctcg aacggttttt tatcaaaaat
     8641 cgtcattttt ccatcaaaat ctgcttatgc aaaattataa aaaaattttg cagtttttct
     8701 tacttttttt gtcgtttaat tgaatgataa aaaccagttt ctttattcag ttaatcaaat
     8761 atgaacgaat tagatatgaa tcattgtatt tgccgttgcg gaaggatttt ttaattaacc
     8821 acagataaac attgataacg attcgcttat tgtaatcaac agattaaatt tcatatgttc
     8881 atatgtacgg atacattttc ggaccgatta attttaacca ttctgtttat ttgcttacct
     8941 attagatatc aataaaaaac tgcttaacag ctatttcagc tgttaagcag ttttaggatt
     9001 tttagttcat attcattgtt tcttataata cagtgttcaa tacttctctt aaagcacttg
     9061 ttgatttgct gaacattgct ttttcttctt cgttgattga taattcaaca acttcacgaa
     9121 caccattttc gtcaacgatt gatggcacac ctgtaaagat atctttttcg tcgtattcac
     9181 cagttaaata agcagataca ggcaatacag cttgttcgtt attcaagata gcttttacga
     9241 tacgtgcagt actcatacca ataccatagt aagttgcttt tttacgatca atgatctcat
     9301 aagcagcatt acggacttta tcagcaatca catctaattc atcttgggca atacgatggt
     9361 ctttttctac aatttcaaac actggtttac caccgacagt tgtatgtgac catgcagcaa
     9421 cttctgaatc accatgttca cctaagatat agccgtggac gctgcgtggg tcaactttta
     9481 atttcaatgc gatttcttta cggaaacgag ttgtatccaa tgttgttcca gtaccgataa
     9541 cacgtgatgt tggcagacca gattcgttcc aagcgatata tgtcaaaata tctactgggt
     9601 ttgaagcaac aacgataata ccgtcgaatc ctgatcccat gatttctttt acgatttggc
     9661 gcatgattga cgcatttgtt ttaactaaat ctaaacgaga ttgaccaggt ttttggttga
     9721 taccagctgt gataacaacg atatcagcat ctttacattc ttcatagcca cctgaccata
     9781 cagccacatt ttcatcgccc caagccatac catctaaaag gtccaatgct tccccttctg
     9841 ctttttcttg attcacatcg atcaatacta attcattaga gattccttgg ttgatcattg
     9901 cataagcgat acttgttcca acaaaacctg taccgacgat tactacttta cgacttgttt
     9961 ttttcatgaa taaacagctc cttttcataa ctatttgtta ctttcatgaa aagtatagtc
    10021 ttgtttattc attttatcaa catgttaatt ataatagttg ttattataat ttttgatgga
    10081 aacgaattcc tgaatacgca taacagataa atgacaaatg tttacaccta tatcccctga
    10141 taatacaacc aaaagtttag aactgaaaat aaatccaaaa aaattcgctg caacgatata
    10201 ataagacagc aatcgcacct aaaacaattt tccttcatat gctttagtga aagattttct
    10261 tcttaatgtt tatttctcca ttcattggga gtacatgttg aatacttctt gaataatttg
    10321 aataaagaag tcgtttgttt atatccgata cgattagcga tttcttccaa cgaaaaactc
    10381 gtttcttgaa tcagttccaa cgcaaagtcg aattttttct ttagaaccag ttcttgaaag
    10441 gaagcatcaa aatacatttt caatttatta ctaagataga ccggattgta gccaaaatga
    10501 gctgctgttt cttttaacgt acaagaagta aaatgcttat cgatataatc taatactcta
    10561 agcatctcat tttctgcgca tccatctgct gatgaaaagc tttgttgttc taataaatga
    10621 gtcaattcga tcagtaatag tgatgtatag agatttaacg aacggatctt atgactgtat
    10681 gtatcaaaat aaatcaacag catattttca atcaaatgcg tcaaacgact tgtttttccg
    10741 ccgcgaaaat gaatgaattg tgtatgttcc cctttttctt ttgatgcatt tatcaaaaaa
    10801 gaagaaagta gattatttgt gcttgccaaa tgattcaata tctctgtaga taaggtttct
    10861 tcttttaata agatgttgat taaaatatcc tcttgccctg tgtattcgat tctttgagta
    10921 gcttctttat caatgatcac cacgtcactt tcttccatct ctatcctttc tccattaata
    10981 atttgtaaac atgtaccgct atacatataa ttgatttcaa caaaatcatg tgtatgctcg
    11041 ggaacttccg catatcgacg gtgtttactg atatgaatat ttccctgttg aaatagatcc
    11101 cctcggtgga tttttggcgg tgtctgaaga tggtaagcta agtttaaatc attgatattc
    11161 attccttgtt cacgctgcag agtttcgatt gattcttcgt tacgcaaaaa aaatgtctaa
    11221 ttcagctagt tccaattgac tccctccttt ttgtaagcgg tttctttcgc ttattagttc
    11281 acgctgtact gctattatat gcaaagctat ttttggtttc ataaagactt tctatggttg
    11341 ggacatgaac ttcctgtgat tccgctattg agagaataac cacttcatac tatatttttg
    11401 ataagcgctt acaaaaatga aaggaacatg cttatgaata aaaagatgat gaaattttct
    11461 ctgctgtcag tctctcttat tttgacttct gctggtgcag tcacgtctgc aattcccagt
    11521 atgtcagcta cttatgccac gcgttcttta tctgctgttg aattattaac gactgctccc
    11581 tcttttatgg tcactatttt tgttttgatt agtagtttta ttgctaggaa aatcggacaa
    11641 aaacaaactg tgatcatcgg attagtgatt gcatcgattt gtggtatcct ccccctcttc
    11701 tcacaaagtt acagtattgt cttagcttca agagctggac taggtattgg ctttggattg
    11761 atcaattctt tggcagtcag catgattgct gccttttatc acggagatga acgagcctct
    11821 atgattggtt ttcaaagtgc atttcaagga tttggtgcag ctttaatgac atttgttgca
    11881 ggacagctag tacagttcgg ttggcaatat acctttttag tctacgccat cagcttacct
    11941 attcttgtct tgtttgtttt gtttgttcct acacctgaaa caactgaact tcaatcgcat
    12001 ggcacagccc caacaagaca agtaatcaaa acgaatccta aaatgattag ttatggtatt
    12061 tttctcttgc tggtcatcgt ggtatataat gctgtatcga ttaaattagc cacagtcctg
    12121 acgacttatt ctctaggaaa cgaaactaat gcagcgaata tcttaacaat catgcaattg
    12181 gcaagtatgg ctgccggagt ttgttttggc tggcttcaga caaaagcaca tcgctatatg
    12241 cttacacttt ctttactact gatgggaatc ggctttgtat tgattgccac tgtgataaac
    12301 ctgtatgtga ttgggtttgg tgcgatccta acaggaattt ctttttcgtt attcattcct
    12361 tacttattca accaagtaag tatccaagcg cccaagtacg cggagagttt caatacttca
    12421 atcttattgg ttggcgctaa tttaggtact ttcattgcac catatggttt gctctttctc
    12481 tcttttgctt ctcttgggag taaaacactt gctgttttcg tcaatggcag tatcttgctg
    12541 ttgattagcg cgcttattag ccttctagta gtacacagga cgaatagaaa gacagtgata
    12601 agagtagatg aagaaataaa agaacaattg acaacaaaat aaatttgatg gaggtcgtgt
    12661 aaaatgacaa atgaaaaaca taaagataga tggctttggt atcctggaga ctttgagatc
    12721 cgccatggac tgctacaaaa tttccaacgg gaagaacgag gttttgactg gccagcgtac
    12781 tggtacatgg atgattgcca tcggaacgtc aagtttaaga gatattactt tcttgatcaa
    12841 ccttccatgt ttaaagtgac gatccaagga gttgggtatg tagaaattaa tggacaaaaa
    12901 catccatgtg gaaaatggct gacttgtcca gctggtaaag caaaaattcg tatctttgta
    12961 ggacatacat cagggctacc agcgatgttt atcgagggag acgaagtaaa atcagatatt
    13021 ggctggacag caagtaattt tattgaagaa tatccagctg gctggagtcc gctttatgtc
    13081 gatatcgcaa aagatccaaa tcaaatctat tatcaaaaag aatgcgtcca tccagtcact
    13141 gaaacggaga ttggcggagg aatcttattc gattttgggc gagcagtgaa tggctgtgta
    13201 gaactaatat ctctggatga ccatatcgaa tctatcactc tatgttatgg agagtccgat
    13261 gtagaagcta tggatatcga ttattgctac tataagcaaa taggaatgac aagaaaaatg
    13321 aaagctcgta aacgcgcttt tcgctatttg tttataccag aggtttctac tggaatggtt
    13381 caacttcaag tttttcatga atttttatct ctttcgaaac aagctgcttt ttcaagcgat
    13441 tcttctttac tgaatcagat ctggtcagta tcagaagaag ccttcaagtt atgtagtgat
    13501 ttgtttttta tcgacggtat caaacgagat cgctggattt ggtctggaga tgcgtatcaa
    13561 tcattcatga tcaatcaata tctttttttt gacgaggaaa tcaataaacg aacgatatta
    13621 gcattaagag gacaaaatga aatcaagcag catatgaata ctatcgttga ctattcgatc
    13681 ttgtggttga ttggtatcga aaaccactat atgatgacga aagactatga atttttacgc
    13741 atcgtctacc ctaagatgca atcattaatg agatacttga tggagcaaac gaatgaatta
    13801 gggtttattt atgggagagc aaaagattgg atatttattg attggtctga aatggataaa
    13861 gaaggaacgc ttgctgcaga acaagtctta ttactgaaag cctatcattc catgatcact
    13921 tgcggagata tcttagctga aacatatgga gagaacgaaa attatcatac tcatctctat
    13981 caagaaaaat atcaactatt gaaacaaaac ctatttgact acttttggga tgaagaactt
    14041 ggcgctttta tcgattgcta tgaatctggg agaagaaatg tgacgcgtca tgcgaatatt
    14101 ttcgctgttt tattcgattt tgctaacaaa gaccaacagc aatcgatctt aaagaatgtc
    14161 ttattgaatg acactatcac acagattact actccatatt tcaaattcta tgaacaagat
    14221 gctttatgca aactcggaca gacgaatatc gtctaccaaa cgattcttga ttattgggga
    14281 gggatgttat ctcatgatgc ggtaactttc tgggaagaat acgaccctac tcaaacagga
    14341 aatgaaaagt acagtatgta tggagatcct tatggaaaaa gcttatgcca tgcatgggga
    14401 gcaagcccaa tctatctttt aggacgctat tttatcggtt tgtatccaac aaagccaggt
    14461 tatgaagaat ttatgataca acctaatcta gattcatttg aaacactgaa ttgtacgcta
    14521 cctatcaaag atggaaagat ttcgcttgaa aaaacaaaag ataagatcgt gattacttct
    14581 gatagaacag gcggaacagt gaaaatgaat ggtaaaagtt atcctcttct agcaaaacag
    14641 ccacttgtct taacaagcta ttcaaaaata aatgcataaa acaaaaaact gcttgcgaca
    14701 tatcagaaga ctttaaatct tcttctgata ttgtccaagc aatttttatt ttgaagtttg
    14761 cttaattctg ttctttagaa acaatgtttg ttctttttcc ggcaaaaaga aagctagata
    14821 atacgacaag taaaaagaaa gcgatgattc caactgtcaa ggctatttga ccgtattctc
    14881 ctagtttccc aagtacaagt cctggtacta gataatcagt atcggcaaat gtagaagaag
    14941 cgattttaag atctcctaat actggaagga taaataatgg cagccaacta atcaataagc
    15001 tattgaaagc agaacctaat accgcccctc ttctaccgcc agtcgagttg ccgaagacac
    15061 cagaagcagc tccgcagaag aaatgtccta ctaccccagg aatgataact gtagtttgca
    15121 agcctatcat agcaaacatg gatagtgttc ctacaaagaa gctaacaaaa aagccaatta
    15181 atacagcatt aggtgcatat ggaaaaacga taggaacatc taatgctggt ttagaatcgg
    15241 gtacgagttt tttagcaatc ccttggaatg ctggaacgat ttctgccaac accattcgaa
    15301 ccccttgaag gacgataaca aacccagctg tgaatgttcc agcttggatc agtgcaaaga
    15361 ttacagcgtt gtctccattg cttagttctc tttcaacaaa tccaggacca gctaacaaag
    15421 caagtgcgac atatacgatc gacatcaaga gcatgatcga tacagtagaa tctcgcaaaa
    15481 agctgaaact tttaggaatc tttatgtcct ctgtagaacg gtctttgttt ccaaaaaact
    15541 ttccgatcca tccactagaa gcataaccga tatttccggt atgccctaac gcaacttgat
    15601 tgtttccagt gatgttcttc ataaacggtt gacaaagagc aggcgtaata gttaatagtg
    15661 ttccttcgaa gaccccgcct aataagatca tccacaaatt tgcagtaaac cccgcgctta
    15721 ctaaaatgac tgctgttaga caagaaacat aaagcattgc ttgacctgta agaaaaatga
    15781 atttatatct tgtgaatcta gcaagtaaaa tattcacgat catccctact agcatgatca
    15841 aagcagtagg tgtaccgtat tgttgcaaag caatcgccac tactgcttca ttgctaggaa
    15901 ctactccttg agtatgcaga gctgtttgga acatcgaagc aaaaggggtt agtgaattac
    15961 tgattaaacc agcaccgccg atcagtacta ggaatccgac aaatgttttg atagttcctt
    16021 ggatcacttc tgaaaatttc ttcttctgaa gaacgagacc aagcagtgca atcaaagaaa
    16081 cgaggatgga gggctgactg acgattgaca caaacaaatt caacaattta tccattgata
    16141 gttcctccct tgaatcattt ttattctttt gacaagatct tcgttacttt ttcttttact
    16201 ttttcgtttg tcaaattaag ctagacaaat catctttacc tacgtaactc aaaaatactt
    16261 ccaatggtgt gcgatagtgt aatgattttc taggaatatg atttcgtttt gatgccaccg
    16321 attggataaa ggtttcggat accttattaa aatccatagc tttatataag ccatctttac
    16381 gtaataagcc attcgaatgt tcatttagtc ctcgttgaga aggtgttcct ggatcagcga
    16441 aataaatcga aatatcattg gtattactaa tctttttcca attcgagaac tcttttccac
    16501 aatcaaatgt gatggattta aacaagtgtt tcggtacaga ttgaaaccat tgattcagtc
    16561 tattctcaat atctatagct tgcctaccag cgggtttcaa ggtgatgatc actttagata
    16621 atcgctcaac taacgtgatc accgcacttt tatgttttcc accgacaatg gtgtcacctt
    16681 ctaggtgacc aaactcatga ttgaactgta tataatcagt tgttctatcc tgaatcgaac
    16741 ggcgaaaagc ttgttttcct cttttttctt tatgtccgtt tggttttctt ttccctttca
    16801 ttggtaaatc gtgagggtca aaggttttat ctttaaacat ccgatatagt gtacgtaccg
    16861 aacaagcaat aggaaactct gctcgaccaa taaggacatc tggagtccac ccttgagcca
    16921 cctttttttg aatgtattct tgttgcccat ctggtaacac aatcggacgt cttccgcagt
    16981 tacgtttgtt tttcttatat tgttcatagt agcttattgc gcttccacca gatttaagaa
    17041 aacgatagac attataaatg gtttgtcgag aacgttgtac cagatgggct acttttgaaa
    17101 cagagtgtga ttgattgaaa taagcttcta tcattacgag ttcagttggt gtaagatggg
    17161 tataggtcat ttgcactcac tccttataat tcttt
//
LOCUS       DAXLPC010000059        17123 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.059, whole genome shotgun sequence.
ACCESSION   DAXLPC010000059 DAXLPC010000000
VERSION     DAXLPC010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17123
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.059"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(131..676)
                     /locus_tag="ACF3UE_001855"
     CDS             complement(131..676)
                     /locus_tag="ACF3UE_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFD3635249.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(688..1380)
                     /locus_tag="ACF3UE_001856"
     CDS             complement(688..1380)
                     /locus_tag="ACF3UE_001856"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFD3635250.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1399..1683)
                     /gene="macP"
                     /locus_tag="ACF3UE_001857"
     CDS             complement(1399..1683)
                     /gene="macP"
                     /locus_tag="ACF3UE_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFD3635251.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1696..2259)
                     /locus_tag="ACF3UE_001858"
     CDS             complement(1696..2259)
                     /locus_tag="ACF3UE_001858"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFD3635252.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2487..3149
                     /locus_tag="ACF3UE_001859"
     CDS             2487..3149
                     /locus_tag="ACF3UE_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFD3635253.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3273..4469
                     /locus_tag="ACF3UE_001860"
     CDS             3273..4469
                     /locus_tag="ACF3UE_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFD3635254.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4570..5946)
                     /locus_tag="ACF3UE_001861"
     CDS             complement(4570..5946)
                     /locus_tag="ACF3UE_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFD3635255.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5983..6849)
                     /locus_tag="ACF3UE_001862"
     CDS             complement(5983..6849)
                     /locus_tag="ACF3UE_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFD3635256.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6938..7963)
                     /locus_tag="ACF3UE_001863"
     CDS             complement(6938..7963)
                     /locus_tag="ACF3UE_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3635257.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7981..8655)
                     /locus_tag="ACF3UE_001864"
     CDS             complement(7981..8655)
                     /locus_tag="ACF3UE_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3635258.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8839..9732)
                     /locus_tag="ACF3UE_001865"
     CDS             complement(8839..9732)
                     /locus_tag="ACF3UE_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFD3635259.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9806..11503)
                     /locus_tag="ACF3UE_001866"
     CDS             complement(9806..11503)
                     /locus_tag="ACF3UE_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFD3635260.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11496..12809)
                     /locus_tag="ACF3UE_001867"
     CDS             complement(11496..12809)
                     /locus_tag="ACF3UE_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFD3635261.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12809..17078)
                     /locus_tag="ACF3UE_001868"
                     /pseudo
     CDS             complement(12809..17078)
                     /locus_tag="ACF3UE_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333417.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
BASE COUNT         4822 a         3843 c         2965 g         5493 t
ORIGIN      
        1 gatttattaa cgtaaaaaga ataagttttt ttaaaataac gtataaaaaa gagcataaaa
       61 caaagtcgtt tgttttatgc tcttctttta ttattttgtg ctttttattt tatcaaatca
      121 ctttgttttt ttataaaatt tctgcgccta gtgtggactc aaaatgtctc aatgcccatt
      181 catgtccaac gggatcgaaa cttgccacgg catctttgaa aatatggagt ttgtatccta
      241 gattatacgc atcgactgct gtatgcaaca cacagatatc tgtacatacg ccggtcaaat
      301 aaatatctgt gatctggcgt tctcgcaaac ggatgtctag atctgttcca ctaaaagcgg
      361 aataatgccg tttgtctatc caataaacat tttcctcttg ctcatagtct tggtataaac
      421 tttttaaaga gccgtacaat tcccgtccac ccgttcctat cacattatgc ggaggaaata
      481 agcggttctc cggatgaaag gaatcttttg gatcatgcgc atcaatggca aaaacgacaa
      541 aatccttttg atcaataaac ttctttgtat gagcagtcag ctttttttca attacttgtc
      601 ctgctgtccc agtagtcagc tttccatcct ctgcaacaaa atcatatgtg tagtcaatcg
      661 agatcaatgc gttcatctta gtcctcctta tacgagatgt ttgacaaatt cgatcaccat
      721 ttctgctgat cgtttgcctg cgtcttcgat aaattcgtca aagctttgtg tcgccgagtg
      781 atctgctgtg tcgctcattg cacgtacgat caaaaatggg atattgaact gacgagctgt
      841 ttgtccaaca gcggctcctt ccatttcgca agctaatgct tcagggaaat tcgttaagat
      901 ttctttgatt ttatctggcg agtcgacaaa tgtatcacct gtaacgatca atccttcttt
      961 tgcgttcaaa ttcgttgctt ttgctgcttt aaccatttca ctgcgcaaat atgtgcttgc
     1021 ttcataatat agaggcattc ctggtaattg tcctgggttg tagccaaatc ctgttgcatc
     1081 tgcatcaaaa taagctactt tgtctgatat aacgatgtca cctacttgta agccttcacc
     1141 gattccgcca gctgaacctg tattgatcac catgttcacg ccgtattgtt ggatcaacag
     1201 acttgtggta atagatgcta agacttttcc tataccggaa cgtacgacga tcacttcgtg
     1261 gttacctaat gaacctgaaa taaataaagc gcctgcgcgt tcccatgata atggttcgct
     1321 taggttctct ctcaaaattt ttacttcttc ttccattgcg ccgataatac cgattttcat
     1381 ctttttaatt ccttctttct atataaatgc gattgctaaa aaaaccacac ataacattag
     1441 gataacaata ataagagatt tcatcaaaaa agagttccat ttggtcgtct tttcccgttc
     1501 gctgatcctt gttttcgtga ttggtttatt ctttttgctt tctttacgat aaaagctggc
     1561 aatctttttt tcttcttgct gataagctgt ttctgctttt cgctgttttt ttaatgactc
     1621 gcttgcttgt gcttgttgtc gcttgcgaag ttcgcttcgc gtaataagcg gtcctttggc
     1681 cataagccga tccctctact ttcctttggt caatagttcc cagtattgaa tcgcataaat
     1741 cgtctttgca tcacaaatca actgatcttt catcgcttgt tgcgcctctt caagagttag
     1801 atgatacaac tccagtactt cgtcttcatc ttgtgctaaa ggattctcga ccttctctac
     1861 cccttgtgca tgataaatat gaaggacttc atttgcaaaa cctggtgaaa gatacatcga
     1921 agtaagatgg ctcagcgact tcgcacgata gccagtttct tcttctaatt ctctagctgc
     1981 tgtcatttcg ggattttgtc cttctcctgg atcgattttt ccagctggaa tctccaaaat
     2041 cactttttct aaaggttttc gaaattgttt gacaagaagc agacgatctt gttcgtcaaa
     2101 agcaatgatc ccgacaccgc caggatgaaa taccagttct ctcttcgaag ttcctccatc
     2161 tggcaaacga acttcgtcta cagcaacatc aataattttt ccgctataga tttctttgcg
     2221 actgattgtt ttttcttcaa attgctcatt gttcagcata tcttctcctg ctttctttgt
     2281 aatcataact gctttttttt catttttcaa tttttctcaa aaactcctta ttagtttacc
     2341 atagataaac cttagatttt ctctaaatat agaaaatcct tctttagtcc gatactcttt
     2401 atagtagtcc gtatgctaaa ataagtatgt aatcgaataa cgaaaagaat tcaatactca
     2461 acgataaatg acatggaggg tttattatga taaaacgaaa ttggccgtgg cttctagcat
     2521 tggtcttgct atttctcttt gtccgaaaca atagtttttc ttttgttcta ggacttttat
     2581 tgataggtgt agttttagtt ttgtggggac tctttggttc gcgcaggaaa aagggaaaac
     2641 aagaagaaat tcctgcactg actgacgaac ttgaaactca ctatgaaaaa agcggtatga
     2701 cagcgaatga aatttcattt tttcgacaaa caatgaatca aacaaaaaat gagatcaatc
     2761 aattgcaaat gaatatgcag cagacagcca aacttaaagc aatcgatctc cgccatgatc
     2821 cagtcaaagc agcgaaagct ttattcaaag aattggtgaa agaaccaaac cgactgcatg
     2881 aagcaagtca gtttctttat acgcatctgc cgaatctagt tgatttgaca aataagtata
     2941 atgagatcaa tgaccatgag atcaaaaaca aacagaccta tgaaaaacta gaagaaagcg
     3001 cgcagatcat cgaccagctg tcagctttaa tcgcacaaga ttatcaaaaa ttcgttgctg
     3061 aggatctaga tgatatcgac gtagagatat ctgttgcgaa acagagctta aagcgtgata
     3121 ataaatatga accagaacaa aaggattaac tcttttgttc ataaaagaag actcggaaca
     3181 ttcagatgat gtctggctgt ttcgagtact ttttctaaag tagagacatt catgtaagaa
     3241 tcgagaacag attcaacaag gaggaatttt ttatggatca taaaccgact gaaacaaaag
     3301 atgttacacc agttaacgat acacttgaag atttattgaa caacccgttt tcaactccaa
     3361 cagatacgct gaccacttca caacaagcgg agattgatca gctccaagag caacagacag
     3421 ctgctcgttt aattgacaaa ctaccggcgg aacgccaaga acaagctaaa cagctagcag
     3481 caaaaatcga tgctaatgat gcacagtctg tcatcagcta cggatcggct gcccaagcaa
     3541 aattaagtga attctcacaa tcgatgttga atcatgtgca agcacaagat attggtcctg
     3601 taggagattc cttaactgaa ctgatgtatc gtctccaaga agccaatcct gacgaactgc
     3661 gtgccggaga agggaacatc ttccagcgtg tcttcgggaa ggtcaaacaa tcgatctatg
     3721 aagtgacagc aaaatatcaa aagattggtg cacaaattga caagatttca gtgaaattag
     3781 ataaagaaaa agacggtctg ctaaaagata atctgatgtt agaacagctt taccagaaaa
     3841 acaaagacta ctttgatgca ctgaatattt atatcgctgc tggagaattg aaaatggaag
     3901 aacttcaaac aacgatcatt ccagaagcga tgaaaagagc agaagaaact ggcgatcaga
     3961 tggatgttca gattgccaat gattacacgc aattcctaga tcgtctggat aaacgtacgc
     4021 atgatcttcg cttagctaga cagatcacga tccagcaagc accacaaatc cgtttgatcc
     4081 aaaacacaaa tcaggccttg gctgaaaaga tccaagcatc tatcgctaca gccattccgc
     4141 tgtggaaaaa ccaagtcgtg atcgcattga ccttgcttcg tcaaaaagat gcagtaactg
     4201 ctcaacgcca agtctctgaa acaacaaacg acttattgaa gaaaaattca gaaatgctga
     4261 aaatctcagc catcgaaaca gcgaaagaaa atgaacgtgg aatcgtggat atcgagaccc
     4321 ttcaaaccac tcaaaatgat ttgatcgaaa caatccaaga gacattgcgt atccaaaaag
     4381 aaggaaaaga aaaacgtcgt catgcagaag tagagcttgg acacatggaa gaagatctga
     4441 aacaaaaact gttggattta acccaataga tcacctttcg cttgttacta aaacaaacgc
     4501 ccaacaacag tttattacaa ctgttgatgg gcgtttttct tatctttctt ctaacttctc
     4561 cattggagtc tatttctcat tcatcttgct gtgtccatag ccatagccaa aataaatgat
     4621 cagtccaata accattacga taccgaacac gatccatgtc acagtttgca gacgaagcat
     4681 caatacaata caagtcaaga tggagacgat tggcaatagc ggaacgaatg gcactttgaa
     4741 ttctccagct tttggtttgc caaacatttt tctcaacttc agtaagccta gactaacaag
     4801 catcaaatag gcgagcgcca tgatattcgt tagttccgct aatacattca atgggaaaaa
     4861 tccggcaaag aatacagctg ccacaccagc ggcataagtc gcttttttcg gtgtacgatg
     4921 cttttgatcg atttctgtca taaacttagg aagtaagcca tccttgctga cagcaaacag
     4981 taaacgagca agtgaataca tcatcgagat cgttaccgtc agtagcgtta aaattgcccc
     5041 tacagcgatc accgcgccca ctgttccatg tcctacatac ctcattgcaa aagccactgg
     5101 gtcattgact cctagttcag tatacggaac gattcctgtc aagatcagcg tcacgatgat
     5161 gtaaaggaca gtagcaatca gtatcgaacc aatgattcct cttggcacat ctttttgcgg
     5221 gtttttgact tcctcggctg ccattgcaac ggcatcaaat cccaagaaag caaaaaacac
     5281 aagagctgca ccatctagca caccggaaaa accaaaaggc atgaatggct gccagttatc
     5341 aggtttaacg aaaaatattc ctacaatgat aaacaacgcg atgataccaa atttgacata
     5401 taccatggca ttattcaaac gtaatgcttt cttggcttca agcgacacga tgtaagtgac
     5461 gaatatcact acgagcaccg caatcaagtc aatgtatgta ccattttccg gattgtaccc
     5521 gccagttaat gcttgtggaa gttcggcccc taaacttttc aaaaaacctt gcatatagcc
     5581 agaccatccg gaagcaacag aggaaaccgc tagtaaaaat tccccgatca acaaccaccc
     5641 tgtcagccag gcagcaaatt caccaaatac aacatacaga taggcatatg gcccaccaat
     5701 cactggcact cgcgaagcaa attctgcgaa acttagtcca gacaaaatga caacgattgc
     5761 agctaagaca aatgaaagtg acagtgctgg accagcattt tgattggccg caacccctgt
     5821 caccacaaat attcccgtac cgatgatcgc accaattcca agcatgatca aatcagacgt
     5881 ttttagttct tttttcatct cactcgtatg attgagattg atctctttct tacgaaacaa
     5941 atccattgaa gttcctcccc attttaggtt ggaaaacagc gattaaactg ttttcatata
     6001 ccctaaaagg ataccaccta aaatgactaa aaggcaacca acaataacat aaatgagctc
     6061 ttttttcgtt tttctttcgc caaggatgaa aatcccacct aaagtagaga taatgatccc
     6121 catttgtgaa agtgagaagc caacagctaa accaagtgat ttgactgtta gaagcatgca
     6181 gatgtttcct aagccccata ataatccaca gatcatgttt ttccacacaa actgatcgac
     6241 tttaacttta cggaaagcaa agaagcttgc gcctaagatc attccgatac tttgaggtaa
     6301 gataattgac atcgcatcca aattcgccca gttgacgatg atggtatata caccataacc
     6361 aatcgtagag aagatcaatg ctctaaaacc cttaccaaaa tcaagcattt tattatctgt
     6421 atctattttt ccttcgtcat cttgtcgggc agtcaaatac gcaccgctta caagaagagc
     6481 taaagcaata ataccgtata cataatcttt cgtttgtgtc cattcatgga agaaaacggc
     6541 tcccgcaatc gtattcaaaa ttaattgaaa accagtagac aatggtagcc ctacagaaac
     6601 acccatgtac ttcattccat ggaactgtcc attttgtcca acactccaag ctaagccgga
     6661 taaaaatccg atcaagaaaa tccaaggggt gattacagga ctaacaacga aaaagacaac
     6721 taaagaaaac agaaatgcac cgatcgtcat tcctagtgtt tgttgattgg catcgccacc
     6781 aattttacca cttactaaac caatactacc ccatgccaac atagggacta atgctattaa
     6841 aatttccata accaatctcc ttttatttca catgataaga aacttatcag cgaaaacgtt
     6901 aacaacacaa gcactttttt tcgtttctaa cgattttcta acgtttttca ttataaaaat
     6961 ttaagattgg gaaaaataaa gtcattgttg tcccttttcc ttcagttgat tcagccgtca
     7021 aatggatacc taatttttcg gccagatttt ttgctaaata aagtcctaat cctgttgaat
     7081 gtgttttgct aagtcgacca tttctcccag taaatccctt atcaaagatc cgtttcaagt
     7141 cttccgctgg gataccgatc cctgaatctt taactgaaag gctgactcct tgcgcttcct
     7201 tttctatgct cacaatgatg tttccgtgat ccggcgtata tttgatggca ttactaagca
     7261 attggttgaa gataaaagcg atccatttag catcggtcaa aacagtatga tcctcaccaa
     7321 cgatctcgta gcgaatattt ttttggataa aataatttgc ctgactgcgt atcacaggct
     7381 gaatgattcc ttttagtcca tattcttgga tgaggtagtc ccgcgagaaa ctgtcgagtc
     7441 ttgcataata caaaacttgt tctacgtatt catcgatttt tgataattca ttttctagta
     7501 atgtatactt ttgatcgtca atatcgaact cgatcgaacg aactagcaat ttagaagcgg
     7561 aaagtggcac tttgatttca tggacccatg agtcaatata atctttttgg tcttgttgat
     7621 tactgattgc tgattgcatt acttcttggt gttcacggat cagctgattg atatattctt
     7681 ctaccagttt ttcttcttct gtcctcccac cactcaaata attttgcaaa ggggaagttt
     7741 tttgtatgtc ggctaatttt ccccaccatc ttctcttgct caagtaacca cccagcagat
     7801 aaaaaatcag aaagacgccc tcaatcaaag ctaaataagc aattgtgctc aaatcaactt
     7861 tgatgtttgg cgccagccac atcacaaaga tcgtcaatgc aataaaaaac agccatccca
     7921 agatcaatgt ccactgatct ttcaaatatt taaaaaaatt catcttaacc gctcatcctt
     7981 tcagggaacg atatatccct gtcctacttt tgtttcgata tatccttgga tacctgcctg
     8041 ttcgattttt cggcgtaacc gattgatgtt gactgtcaat gtattgtcat ctacaaatcg
     8101 ttcgtcatcc cacagtgctc gcagcaattt ttcccgactt aagatctttc cattgtgctt
     8161 catcaaaata aataatagac gatattcatt tttgctcaaa tcaatgatct ctccgttgat
     8221 ttccatactt ccgttgtcaa cattcaacgt aatgccattg tggctcatca tttcactaga
     8281 taattctgtg tagttgtaag aacggcgaag taatgcattg atttttgcaa tcagtacatc
     8341 gatttggaaa tgttttgtca caaaatcatc tgcccccatg ttcatagcca tgatcatatc
     8401 catattcgta ttcctgctgg agataaaaat gatcggtact ttcgatactt cacgtatttt
     8461 ttgacaccaa taatagccat ccaaaacggg aagattaata tctagtaata caagctgtgg
     8521 ttcttctctt tcaaagtctg agaacacttg attgaaatcg gtcgttccaa aggtttcaaa
     8581 ttgccatttc tcaagttcct ccatgatcaa ttgtcgaatg atctcttcgt cttcgactac
     8641 catgattttt gccataaaaa atccctccat ctttcttctt gctactacaa tatcaaagaa
     8701 gcccttgtga aacaagttgg cttacctgga aaatgtcatt ttagcaaacg ttaaaaaaaa
     8761 ctggaaatat gcgatttaat cgcgtttgtc tcttccaagc agcttaaatt tattatgtta
     8821 ttcttaataa ttggtctatt atctgttatt tttctttcgt tgtttttgtc ttttaaattt
     8881 tcgataacac caataaccga aaagcgttag cactagcaat atacctagaa ggagtataag
     8941 taatcgataa agatggtatt tttttgtctg ttctatcttt gaagagactt cttctgtaaa
     9001 gggaactcgt cttcctgtca ctagtaatcg gtgagtgttc acggtgtaag gtgtacaagt
     9061 gataagtgtg actagatcct gcttttctct aattgctaat gtatttgttt ttgttggaag
     9121 gacaacaatt ttctcaacga cttcataagc gagcatccga ccatacactt caagatagaa
     9181 tcggtcatct tgctccattt cttcaagatc cgtaaagagt tttttctcag caataccgct
     9241 atgggcggta atcacggaat gtgtactctc tcctccagtt ggaaaagagg tgccttgcag
     9301 gactgtcgct cctctatcta acaaaagatc attcgtttca tcaaataaag gcaagctaac
     9361 attgattttc ggaatataga tggctccgat catatgttgt tcgtaatatt cttttcctgg
     9421 attttggaca tttctaaccg cttgctcaaa aggatctttg acttgtccca ttcctgggat
     9481 tactgatgta tgagcaagcg tctgattttt cttttcatgc actgctaatt gttgctcatg
     9541 tttttcttct ttatcgcgtt caagctgctt ttgataattc tcgatccttc tttgatccaa
     9601 ataattgctg agagcatctg ctaaaaatgg atatgtaaaa actgcagctc cggcaagaaa
     9661 catcactgcc ataaataatt gtaataaaag actgatttgg gtttgaggtc tattacctat
     9721 tttctttttc attttcttca ccttcttatt taaaaaaact gcagcaacct ttataaaacc
     9781 gattgctgca gcttattttt gttgcttata cttcagactt cattttagat ttacggtacc
     9841 agctgtacgc tccaatcatc aaacttattc cgattagtaa gaatgccaag agcccgttcc
     9901 caccagtagc aggaagtgac ccgcgtttca tattcggtac tctttctggc cctggatttt
     9961 ctactcctac gatctgaatt tcttcattat agcttccata agagatgata aattcagtaa
    10021 aggctgcctc acctgttgga agtacataac cttctggcgc catggtctct ttcatttgat
    10081 aggttccata atctaaccct tgaacctcaa agtatccatt tccatctgcg acaaattctg
    10141 ttgcttgtcc gcttgttgcc cactcaattc tatctgctcc tgattcataa acagctaaag
    10201 gcgactcccc tttataaaat attgcgtatt cagaacggtc ttcattccac aattcgaatc
    10261 ttgcatcttt aagcaattca ctgcttgatg catcatattt ttcaaacttt cttccacctg
    10321 ttgtgacttt ctctggcggc tctactcctt cttcataatc aaattcatca tttcgtccga
    10381 tttcaataac cgctgtgttg ttatggaaat catccgcttc tagttctgtg gaaaccttca
    10441 aattatacgt gatcgttaaa tctcctccac gtgcatctgc taatctacct aaagtatcta
    10501 ctttggctac tccattttct tctgtcaaaa tcgtcacgac aaacccgttg cttactactt
    10561 ctactatata atcttgtcct tttgttaaaa tcgtctcgcc ggctcgcact tctatttcct
    10621 gatcataata agttagacca actgtaggcg tatctgtgat tttgtaattt ttgataacag
    10681 cgcttccgtt ttcaaggaca gaatcgatga aataaggaat aggtgctgtg atcgtgtaag
    10741 aagccgtttt tcctctttct agatcaatat aagaaatcgt ttcttgttct ccagcttcat
    10801 taataatcgt tacttgtcta aggtcgcttt cctctacatt catctgttta tctgcttctc
    10861 tgatttcgtt tttcggatac aaatgcacat ctgtattgta tgtgtctttc catgtagaac
    10921 catcccacac gccatccacc atatcaggca tcatcactgg catcataaca accattggag
    10981 acgcgattct ggaaatatga gctggcgaat aagtttctaa gaaaagatag actttatctc
    11041 tagaagaagg tgcttcttcc gtcacttgga cggtagagaa taccgcttct ccagcttcat
    11101 tcgttgtttg tttgtcaata cttgtcagtc gatattttaa aaaccaactt tctgtgtgcc
    11161 gtttttgaat ccattcaatc gcttcggcag aattaagacc gtcttctcgt tccggtgtta
    11221 aaggattatc tcgaatcaaa tcgtaatata cttccgttac gtcaaacaaa tcaaaatcga
    11281 ctcctggaat attttcttca ccaaaatccg tagaaaccaa tccgctattc ggtcgttctt
    11341 ccggaacaga tgagaaacct tttttgtgta atgtaatcgt cacttcactt ggtttttgtg
    11401 cgacttcttc ggctttgact agttttccgt tcccgaaaat ccctattccc gcagtaacga
    11461 gtaacagtac actcattccc gtgacaatca tttttttatt catttttttc tccccgttct
    11521 ttttttatta ataaaacagc acctaacaat aaaagaattc ctagtaaaga aatcaacgtt
    11581 cttgcttcat tcgtttgcgg gaatacggac cattttcctg attgacctgg attgcttgga
    11641 ccactcggct ctttcggttt gtccgttgtt tcttttacgg tctcgttata aacacgtggt
    11701 gttgcggatt cataggcaga gactggaact ttcccggatt ctaattcagc catctcctgt
    11761 ccgttaacta ctacatattg tggttggcct tttgcatcca cccaaaattc agggatgatg
    11821 acctcgattc tcttacttgc ttcatccatc tcgtaacctt ccacaccttt taattcttca
    11881 aaataatagg tgccagaagg caagaaacgt tgtcctgtcg taacaaggcc ctctttatcc
    11941 gaaatgaatt tgcttacatt tttgtcattc aaaggatcat tgtctgctgg tttgatccat
    12001 tgatttttca agtcattagc aggagccata tctaaataat atttcccccc ttctatcatc
    12061 tgatatagag caaaaacagc accttctaat ggttttcctt tttcagttgt tcctctttga
    12121 cgtccatact tgaagaagta tggatctctt agataaccga catttttagg atagatatga
    12181 atctcttgca gttcctcggt tgattctgtc gggtgataaa ttggcaaaat agcagcaatt
    12241 gggatagctg tctgatcgat atcaacatcc aatccaactt ctggatcaat cgattcttcg
    12301 aaaatcaaat aaactgcatc ccgatcttgg tttttcttag gtgctttgat acgtgcaatc
    12361 ccgtctccta atccgccaac cgtatctttc ccagttgtta ccgaagtccc tatttggaca
    12421 agcctttctt ctgtgattag ctgacggata ttgtttctgt tcgtttcagc gatttgctgg
    12481 acgaattctt taggagtcat gttttcagca gctttttttt catgataata atcggtcatg
    12541 tcgtaaatgg caaatgtcgc tccatttagt ggcaccgtct gtgaaatgat atctgctgtt
    12601 tcccctgctt cctcagagat agccaagcca tcattttcat ggtattcaaa ttgatcgtta
    12661 taatcgatat ctcgaatcat ccgtttatgc aacacgaatt ccacgacatc ttcccctgat
    12721 tcttctgccg acatcgcatg tggaagaagg actgctgcaa gcggtagtaa aacaagtaat
    12781 tgaagcatca aacacaacag ctttttcatt accttgctcc ctccttttta gattgtctga
    12841 caaacaaacc ataggctgct cctgcaagcg ccatgaagaa tgcagcaagc aggatataga
    12901 ataatcgtcc ggatcctcct gtagcaggca acggattttc aggatcgttc ccgacactaa
    12961 gctgtaatct gattcgattt gtctccaaaa gttcatattc taactcttgc tgtagatcag
    13021 gcgtctctgc ttcttcgttt ggataatacg aaatctcaac ttttagtgta cccgcttctt
    13081 ttcctggaac tacccgatca ttttctatgt caggttcttc tcgataacta atttctaaaa
    13141 taaagtaacc tggaagtttt ctatagctgt caggtgactt cacttccttg atccgataga
    13201 ccccttccaa caagtctgaa gcattgaata gggaagaatc gtttggatct ggtgccaagc
    13261 ctccctcgat gatttcatac tctcctgcac tattttgttt ctcaattgaa aattctgcgc
    13321 cttcaagacg tcggctattc atactgtcaa ttttcaaaag ttccaaatcg attggcgcta
    13381 gttcatcttc taaggttact tgtagtacac catcgatgat ttcatagcct tccggcaagg
    13441 gagcagtttc gtcttcgatg accgtatctt caatgataaa cttaccttct tcattcagtg
    13501 caaactggaa cacttgatca gatagccgat acccatttgg tgcgacagat tccgagacct
    13561 catattcacc aatagacaga tgcagaggtt ggtcgtaatt taaatcgaca tacttttcta
    13621 ctcctacggc acgagaatag aagtatccga tcccaggcaa acgtttcgat tcttctggtt
    13681 ctaacggatt accagtgtat gctcgataca gcgggaagga agaatccccc actttcctga
    13741 tatcgaaacc tgcaccatct aatgtatggc cttcatggtc taattttcta actcggatct
    13801 cccgataatc aaacgtattg taagcagtga atgctaccca taaacgatcc tcttcatctg
    13861 ttgtatacgt gagatattgc caattttctt cacctgtttg cttgagttgg atagtcccta
    13921 tagcattatc gtaaagtcgc aagatccatg tgtcattttc atcaggttct ttgaaacctt
    13981 ctgggttctg gctctcaatg attttgtatt ctgcatagtt ggtagtttct tcactatcct
    14041 tataaacaaa tgaatctggc tctccgattg gatgaataac tttctcacca tccacgatta
    14101 catatttccc gtcttcatct actgaataga acgtgagtct ccctttctct tcctctactt
    14161 cgttcacacc agaaagccct ttcgctactg gatatccgat ttccagtccg ttaccatctg
    14221 tttcataaag ttcaaactct gcgccattga ttggcatatt actgccttca attagtttat
    14281 tgatattcat gtggattggc ttgaattcat ttcgcatttc cagtttgaca tacaactcat
    14341 catactctgt gccttctatg ttaggctctt gtacaacaga aagcttgtga tattctcctt
    14401 cataatagga attcggatct ttaccttccg gtccgccgac tctcgaacca gatgtatatt
    14461 catctacaag ctcgtagtga cctaacatct catcttcgtt ggctgcatat tttttgattt
    14521 ggaattgata cgtctcatct actaactgat aacgtggtgg tccagcgatc tctctgatcc
    14581 aaaatatgtc gctgactgct ccagtttcat ctcctaaaat cggcatcttc gtttcaaaga
    14641 tcgctattcc gtccgtggta gttttacttg tttcgattgg ttcggcttcc ccactctctg
    14701 gattttggtc atataatgca aattcgactc cagccaacgg ctcgccattt tgacccttct
    14761 tgctgacttg gaaattacgg cctttatgtt cgtaacgaat ggaagaagat gggaaataca
    14821 tccgtccagt agtgatatca ttctcataat cctccaggtt ctgaatatag gccatattgt
    14881 tcactgtgca aaaatttccg tcttgagctc ccgcatcaag ttttacttgg tacttgatcc
    14941 tgaccatttc cccttcacct aaagaaatcg gagaaaattt ataagcttgg ttttcccgtc
    15001 cgacatacgt tgtcggagtc gccactactt ctggtggggc ttgtccatga cgttcttcat
    15061 cccatatttc tggctcttgg tacttcatgc cgttttctcc tggatctaga tggtaaaact
    15121 gaatatctgc cgatctgcca gctccaaatg gtgagacatt aaaaccagtt tcatcataaa
    15181 gtgtggcttg ctggatcgtt ctcttgaagg tagaagagat atcctccaag gctgtaacaa
    15241 tgtcattctt gttgttcgca ttgtaatatc gcggtgttac gccatcttct tctaaatcag
    15301 caatattttt caatacattt cgtccaatag catctagtcg ttgtctcccg ctaacgtttc
    15361 catcgattcc taaaccaatg gagaagatac ttggcgggtt ctcttgatac ttgtttttca
    15421 gccaatgatg ataagcaact gtgttgatcg cagatgactt ttcttgcgaa gtaggactgc
    15481 cattcgtatt gttattagaa gaaccatcac caacccagtg agtcgcttta ttatctcctt
    15541 cttttacctc tccataacga tagtgtacat ttacttcatc ttctggacgg ttaaagtcag
    15601 atgcataggt aactggatga gtaaaccctg cattagaagt attcccagaa aactcctcaa
    15661 aatttctgaa caaaacgtca ttatcttcag caatcttatc ttccatcaca gtccagttgc
    15721 tccaagctcc attagtgctc gtacgataac ttgactgaat cggtgcataa ctgaaggtcg
    15781 gtgtcccatc tcccacaacg attaggattt tttctggatt tctattttct ccgccattgt
    15841 ctttatacaa tgtttcatag ccatttttaa gccctagtgt aagcggagtt cctccgattg
    15901 gtgtacgatt taatgctgta ttctcacttc ccgtcaaacg attgatatca tttgtcaatg
    15961 gaaagatgtc cgaactgatt tgctcatggt tattgatagc tgtactatta tggtaaaaat
    16021 tcaccatacc gattcgaata tccagactcg ggtcagagag cagatcttta ctcatttcgt
    16081 ttactgcctc aatcaacgca gcatttttag tttgactatt ggtcccagcg gttaattcac
    16141 tcatactcgc tgacttatct agaacaaaaa cgatatcgat tggactgatt tcctttttct
    16201 cgcccccgat gacatctaga tagacattgt aaagggttgt tgcatcttca ggatgtagat
    16261 cagatgctgt gctgcttggc agaacaggtt ctacccattt tttgatgtac gccccgttat
    16321 aatccaagta actgttttca aaattccgtt catttcccca aagctgaacg gtttgagctg
    16381 gaacgtttct atcttcttcg cctgcagttg atccattatt agtagcatag tcgtaatttc
    16441 gccagttcgc tcccccgttt gtataatcac tatcatcgat caagttctct ccgtcatatg
    16501 gcgagccttt gtctccttga tagcgttcat tgctttgtgt ccaatttcct aacacttttg
    16561 tatagtcatt cgttgtaaac ttcatctatt ctttcatcaa ccaccacttg aagaggtagt
    16621 tacccttcgt tcacatcggg gatcttttct gtttcaaaaa tcaatgtgcc ggtttctgct
    16681 tcttttgaat aaacttttcc gacataccat tcttgaccat cgatcgtctc gacttttagg
    16741 tcttctccat cttcatcata ggaggataga cctgttccac gaacgttttt tacggtacca
    16801 atcccggcgg ctgccgcatc gattgctaaa cgtattctac cttcattggc actttccttt
    16861 ttttcaaaag ccagatgcca ttcaagggtt tcttcttttt caatatactt cccttcaatt
    16921 tttgcatagt cctcatctaa gaatacctca tcctcctttg tttctgttga ctcagcagct
    16981 acatccaggg tcgtcatatg atagactgac tggaaatatg gtccaaatag caaactgaca
    17041 gttactaact gcaaaagctt caattttaac cctttcacat ccttatactc ctttcaaaaa
    17101 tatttgtctt ctttcacaac aat
//
LOCUS       DAXLPC010000060        17050 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.060, whole genome shotgun sequence.
ACCESSION   DAXLPC010000060 DAXLPC010000000
VERSION     DAXLPC010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.060"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..251)
                     /locus_tag="ACF3UE_001869"
     CDS             complement(<1..251)
                     /locus_tag="ACF3UE_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3635262.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSNEIKVFIKE"
     gene            complement(248..901)
                     /locus_tag="ACF3UE_001870"
     CDS             complement(248..901)
                     /locus_tag="ACF3UE_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3635263.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            1189..1709
                     /locus_tag="ACF3UE_001871"
                     /pseudo
     CDS             1189..1709
                     /locus_tag="ACF3UE_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(1707..2426)
                     /locus_tag="ACF3UE_001872"
                     /pseudo
     CDS             complement(1707..2426)
                     /locus_tag="ACF3UE_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010745868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
     gene            complement(2377..2586)
                     /locus_tag="ACF3UE_001873"
     CDS             complement(2377..2586)
                     /locus_tag="ACF3UE_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635264.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            complement(2568..2636)
                     /locus_tag="ACF3UE_001874"
                     /pseudo
     CDS             complement(2568..2636)
                     /locus_tag="ACF3UE_001874"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            2863..4136
                     /locus_tag="ACF3UE_001875"
                     /pseudo
     CDS             2863..4136
                     /locus_tag="ACF3UE_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4243..5274)
                     /locus_tag="ACF3UE_001876"
     CDS             complement(4243..5274)
                     /locus_tag="ACF3UE_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635265.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(5281..6111)
                     /locus_tag="ACF3UE_001877"
     CDS             complement(5281..6111)
                     /locus_tag="ACF3UE_001877"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3635266.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(6108..6923)
                     /locus_tag="ACF3UE_001878"
     CDS             complement(6108..6923)
                     /locus_tag="ACF3UE_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3635267.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(6920..7744)
                     /locus_tag="ACF3UE_001879"
     CDS             complement(6920..7744)
                     /locus_tag="ACF3UE_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HFD3635268.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(7734..8834)
                     /locus_tag="ACF3UE_001880"
     CDS             complement(7734..8834)
                     /locus_tag="ACF3UE_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFD3635269.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            9012..9797
                     /locus_tag="ACF3UE_001881"
     CDS             9012..9797
                     /locus_tag="ACF3UE_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFD3635270.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            9830..10213
                     /locus_tag="ACF3UE_001882"
     CDS             9830..10213
                     /locus_tag="ACF3UE_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFD3635271.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            10289..10420
                     /locus_tag="ACF3UE_001883"
     CDS             10289..10420
                     /locus_tag="ACF3UE_001883"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3635272.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            10389..10625
                     /locus_tag="ACF3UE_001884"
     CDS             10389..10625
                     /locus_tag="ACF3UE_001884"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3635273.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            10637..10723
                     /locus_tag="ACF3UE_001885"
                     /pseudo
     CDS             10637..10723
                     /locus_tag="ACF3UE_001885"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
     gene            complement(10703..11674)
                     /locus_tag="ACF3UE_001886"
     CDS             complement(10703..11674)
                     /locus_tag="ACF3UE_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFD3635274.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            12308..13768
                     /locus_tag="ACF3UE_001887"
                     /pseudo
     CDS             12308..13768
                     /locus_tag="ACF3UE_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(13691..14104)
                     /locus_tag="ACF3UE_001888"
     CDS             complement(13691..14104)
                     /locus_tag="ACF3UE_001888"
                     /inference="COORDINATES: protein motif:HMM:NF013068.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3635275.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIADCRQKLFQTRNSSLEQLFIYFVSNF"
     gene            complement(14234..15610)
                     /locus_tag="ACF3UE_001889"
     CDS             complement(14234..15610)
                     /locus_tag="ACF3UE_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3635276.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(15610..16266)
                     /locus_tag="ACF3UE_001890"
     CDS             complement(15610..16266)
                     /locus_tag="ACF3UE_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635277.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(16276..>17050)
                     /locus_tag="ACF3UE_001891"
     CDS             complement(16276..>17050)
                     /locus_tag="ACF3UE_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFD3635278.1"
                     /translation="EVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSEN
                     MVFVDYSTSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDS
                     NAFEESLESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKI
                     QIIMQFIFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSN
                     ITTLGQSYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
BASE COUNT         5213 a         3621 c         2910 g         5306 t
ORIGIN      
        1 ttttctttta tgaatacttt tatttcatta ctcttggaat aaaactccaa agtttgttct
       61 atatatttta tttcttttcc attcatatta ctagaaattt catttgccat attatgaatc
      121 ttttcttttc tcgtctccaa atatgtttta ggaaagataa aaaaaattaa tgaatgaact
      181 aatataatta ttattccaag aacagaaaat atttgtatga acatttttgg aaatatcttt
      241 aattttttca ttttctctcc aatttatatc ctacatttct tatagtagtt atacagtcta
      301 attgtaattt ttttctaagt tcttttatat atacatctat tactcgatca taaggagttt
      361 cttcgctatc tttccataca taatcaataa tttgcattct tgttaacact tgtccattat
      421 tatccaataa acattttaat acttctagtt cttttgcatt tacatctatt tcttcaccat
      481 ttattttagc tgtatagcta ttaaaattaa ccgatagatc cttatattca aacttctcta
      541 aatgtccata attcttctta attaaagaat ctattctagc ttttaagacc ggcaatgaaa
      601 atggcttttc tacatatccg tctactaaat tagtaaatgc atcaatttta tattcttcat
      661 cactaaatgc agtcaagatt agaattggta aattgctttt ctttctaatt tctttcaaca
      721 cttctaaacc atttataaaa ggtatctgaa tgtctaagat aaccaaattt atatcgctat
      781 taaattttga caaggcttct cttccatctt tagcttgaat aacagtatat ccaaattctg
      841 aaagatattc acttattccc tctcttatca tattatcatc ttcaacagtt aatattttca
      901 tatatacctc cacttaagcc tatacactag atattataca gcatattatg gctctataat
      961 atctagtgtt ggtgacgcct tctgttgcca atactttttc ttttttttaa taaatgcaaa
     1021 cagacacctt gaaatccttt agaaaaaagg cttctataat attttgtgtt gttggaaaat
     1081 cgaaggcgat tttctactaa cactttttct tcgtttcaac tcaaaaagag actcactttt
     1141 ggtaaaattt agtcgaccaa aacatcaccc taccaaagga gtcgctctat ggataatcat
     1201 actagaaaat tactcggatt aacagataaa catttatttt ttgatgaaga atggctgatt
     1261 gaaaaagaat ataaaggcgt tcaagcgcag tttattaaag ggagattgga tgactcacct
     1321 tcccattgtg aacactgtgg atcgattcgt attatccgca acggttccta tacgacacgt
     1381 actcagatgt tgaaagtcaa agaaaagttg actattttag aattaaaacg tacccgtttt
     1441 ctatgctatg attgtgggca gaccttttct gcgaaaacgg acttagttga tgaacatcat
     1501 caactaacaa aggaactgaa gcaggcgatt ctcatagaac tgtacgaaaa tcaatcacgt
     1561 aatctgaaaa tcagaagaag taccgtcggc tcaagcgata ttggaaactc ttactcaaag
     1621 attccacgac attggagccg ctcaaacggc attatcatcg actgtttaaa cgaccaatta
     1681 gtcaaacaga aatcgtcgat gaaccgttgt gcacaatggt gtcctgaacg tacagcgaca
     1741 ccttccatat ccagagcagt cgccacatca cggggatgga tgccatccaa attaaaagca
     1801 accacgccag tatgatgttc aggatcttgc ggtccgtaaa tggtgatacc gccgatcgct
     1861 tgtaatttag gtaaaacgta ggcaaccagt tcttgctcat aacgatgaat attctccata
     1921 ccaatctcat tcaagtaatc gattgctcct gcaatgttcg gagtaccagc ttcaaatttc
     1981 catggcagct ctttccatga actatcgtaa agattgacaa aatctatcat ttcaccgccg
     2041 aattcgactg gctccatttg ttctaacaat tgacgtttgc catataatac accgattcct
     2101 gtcggcccgc acattttatg cccgctaaag gcgaaaaaat ctgcatccaa cgcttgtaca
     2161 tcaactgtca tatgcggtgc tgcttgggca ccgactggac tatcctcaac tacaacagcc
     2221 tgttcaaccc tcagccgttt caagcacaac aaataacctt ctggatctgg tttgccgacc
     2281 tgaagatcat cgatcgtcac aaaggaatca attttttcct taatcatcgg atgtgcttca
     2341 aaaaaatagt ctagctcccg cagttcagaa ttgagactac tccgattttc cagtgctgct
     2401 gatccgctgc tcaaaatgtt cagcatccac tggtctccca accgcttgac ttatcccttc
     2461 ataaaaggac agttctgctg ccgtcccaac accttgttga tagtctgcaa aaggaatttt
     2521 atagccgaac tgctccagta aataggcttc agtaaatagt gatgaatact ctcgtaaaac
     2581 atccattcac tgtcaatcat cgtcccatca aaatcaaaaa taagtgcttt ggtcatcttc
     2641 tttccccctt acccaaaaca agcaaaagct gtgtcctgct ctctctacag tatcagcata
     2701 aaaactgccg tctgaaaagt caaaggtgaa agaaatgtgg cgctataatt tctaggactg
     2761 atagtaaatc attctatcag tccttttgag cataaaaaaa caaaacatac agaagctccg
     2821 ttagaattga atcaccacaa cacaatcaaa ggagcgttct gtatgcctga tcttcatctt
     2881 atcaaactat tactaggaat caaagatgga aacattcaaa tcactcatgt cgagaagaaa
     2941 aaaatacatt caatcaacag tatcgttgtt tctgccacgc tcattaaaac gattcagccc
     3001 tgtcctcagt gtaaacaggt gaatcaacat gggctgatcg ttaagaacgg aaagaaaaaa
     3061 tcgctggtcc ttctcaataa gtgtgcgaat caacggactt atcttgcttt ggcaaagcaa
     3121 cggtacctct gtcgtggctg tcacacctat tttacggcga atacctacat tgttgaaaaa
     3181 aactgtttta tcgccaaaca agtacattat aaaatattgg aggaattgac tgaaaaacaa
     3241 gcaatgacga cgatttctaa acattgcggc gtttcttggt caaccgtttc gcgaacactc
     3301 gcttctctgc tccccatgac aaacgtgaaa ataaattggt tgcctcgctg ttcattggta
     3361 gatgaatttc gttcattgaa aaatcaagtc ggtccctatt ctttttcttg tatggatggc
     3421 gatactggga aattactgga tattcttcct tcacgtaaga agaaagatct catttcttat
     3481 tttatgcaat ttgaacgacg tgcacgttta aacgtaaaaa tactcgtaac agatatgaac
     3541 gcctcttatg ctttgctgat aaaagagtgc tttcctcatg ccaaactcgt tgtggatcgc
     3601 tttcacatcg tcaagcacct cattcgcagt tttaaggata tttgactatg agtcatgaaa
     3661 agcttcgacc gaaacgatcc aatacaagcc aaacactatc gacaagtgaa ggctttatct
     3721 cgacttctga tcaaacgaca ggacacgctt gtttatgata aatggacaaa atggcgtaat
     3781 tttggttggg cctatttaac cgaaagtgaa gtcgtagaac gtctactttc tacttctgat
     3841 gaactacgaa tagcttatgc ttactatcaa gaaattcttc aagcttttta tgacaaagaa
     3901 gcggacatct tctttcagct tgtaaaaaca atgcccaagt cggttccaag agaactgcat
     3961 catataaaaa aagcgtttat aaactatgaa tccggcattc gtttagcctt agagttgcct
     4021 tactcaaatg gcaaaataga aaatctgcat acccacatca aagcattgaa acgaatagct
     4081 tacgggttag gatgagaacc agaattttct taatcaatca tctgatcact tattaaacat
     4141 aaaaaaacat ctaaagcaga aaatcaattc taccttagat gttcttatat cactctatca
     4201 gtcctatttg acaaagagcc agaaatgttt gccgactata cactagcttt gttgtgcaaa
     4261 atgctgagta tcaatttcca cagggattgc tagaatatct ttcagctgaa tgtataaggc
     4321 atcgctaatt ttctcttccc gatcgttcaa ccgatccact aaaatttctt tgccctccag
     4381 cgtttgaaaa acataccgtt gaatgttgcc taaaataaat gattccttcc atagaaccgg
     4441 aatcttaacc ccctgaggaa ccggttcaaa ttgaatcagc tccggtctta aataataaat
     4501 gcagcgattg cccttagcgg aaaactcgtg ggtatactga ttcagctcat accattcgaa
     4561 acgattatag ttgccgataa attccgcaac aaatcggctc tgaggattct gatacaattc
     4621 cttcgaggtg gaaacctgag ccacccgccc agcttccatc acaaaaatcc gatcactgat
     4681 tcgcatcgcc tcttcttggt catgagtcac aaaaatcatc gtcatcccta gcgattgctg
     4741 gatagcgcgc aaatcccgct gcagctgttt tctaattcgg gcatccaaag cacttaatgg
     4801 ctcatccagc agcaggactt tcggttcagt gaccaatgag cgagccagtg ccacccgttg
     4861 tcgttgaccg ccagaaagaa actggacatt tttatctgcc tgctccgtca tatccaccaa
     4921 tgatagcatc tcaaaaacct tttcctgaat cacctcagga ctcagcttct ttaccttcaa
     4981 accaaaggct acattttcaa aaacagtcat agttggaaac aatgcatact gttgaaaaac
     5041 aaagccgata ttgcgatcct tcgtaggctt atcggcaata ttctcattgt ccagcacaat
     5101 ctcaccgctc tttggttgtt ccaatcccgt gatacagcgc agcaacgtag actttccgca
     5161 cccgctggga cctagtaaag taaccagctc acccttttca atctgaattt catcaatagc
     5221 taaaatctgt ttttcatcaa aaaacagatt gagatcatgt atttctaaaa acattttccg
     5281 tcacaactcc tttaagggct tctttttcga ctgcttctct tccctcgtct gcttaaggga
     5341 cagctgttgc ttttgtcgat aagtcagcat aaaggtagtt aaagcaattc ccaccataaa
     5401 cagcaaatac aaaaccatca cagcgctagc caaatggccg ttttcgttca tccgccgcag
     5461 catatagatg cgtaccgtct gaaatcgacc gccaatcaac aggttcgtca gcatgtactc
     5521 cccaaaaacc gaagaaaaaa tcatcagaga aactagggtc acaccgatac ggatgtttgg
     5581 aaacagcacc tggataataa tcgtagacat cggggcgccc aaggtttctg ctgcatccac
     5641 taattccttc agattaatta agcgcatctg gttgttaaga ctaagataga caatcggcaa
     5701 cgccgtaata aacaatgcac ctaccaacac tacaaacatt gggataccag tttcagcata
     5761 cgttcgaagc aaagccgtta ccaaaatcac tcctggtaaa gcatacggca gcaggagcag
     5821 cttttccagc caacgattca aacgagggaa atacaaatga atccaaataa tggtgggaat
     5881 catcaacaac agaatcgtca ccaagaccac acctgctaat aaaagtgagc gacccaccgc
     5941 agcaataaat tccctgtccg tcagcagctg ttggaaccat tgcaaggtaa aatcactagg
     6001 taaaagcgat tttgaccatt tagtggagct ggcatacaaa atcgttccaa taatcggcag
     6061 caagtaatac aggacaaagc agaacaaaat cggttttatt aactttttca cgtctgcacc
     6121 accttgcctt tcttttgaat aatcaacatt gccgttacca gcaggacacc taaagcgact
     6181 gccaacgcac tgcctaaatt aggcttggcg aacacatctc ccgacactaa agccgcaatt
     6241 cgaatcgtta aaagatttac attactgctg gtcagggcat acgctgtttc ataggtcccc
     6301 atgccattag caaataagat gacaaaggtg ctggcaatcg atggtcgcaa aaaaggcaaa
     6361 gccaccttga accaagcata cgctgatgaa gcgcccagca attgtgcgga ctccagccat
     6421 tcctttttca cttccttcat gctgggatac aaaaacaaga cccctaacgg aatttggaaa
     6481 taggtatacg tgatggtcaa tccccaccaa gaatacaaat tgaagtccgc tagaaatggc
     6541 aaaatcattt tcagcacacc tacattcccc aacaaaataa taaaagagaa tgccagcgga
     6601 atcccagcaa aattagctgc caaattggaa acaaaggtga ttttctcctg caatttagtc
     6661 gatagattca ttaagcataa acataaaata aacgtcccga ttaacccaat cacactggag
     6721 ctgacagcaa tcagtacgct gttaacaaag gcctgtgtgt aatatttgtt gctgaaaata
     6781 tcactgtaat tggccaatgt ccactggtta gttaaatcac tgtgcaagct gcacagaacc
     6841 ataaaaagca gcggcagcag taaaaatgca cagaagataa aggaggcagg aaccagaacc
     6901 aagcgttttt tcatctcttt catcccctca tcaattcttg aatgtcctgc attttctctg
     6961 acggtgcaat tcctaataac cagcaaaaca atggagccgc cagcagctgt ggtacagttt
     7021 gttccttcag cttttggcgt ttatttgaaa tcaaataaaa aggaacttca cgatgtgcag
     7081 ccaagctgcc gccatgcagt ccgtgcgcat ccatcccgtg atccgcagtc accacgactt
     7141 gataaccttt ttgcagccat tcaggaaggt aaatagccaa taatctgtcc gcctgattaa
     7201 ccgctgctgc atattcatga gaatcggcgg taaatttgtg accgacatca tcaatattca
     7261 tcgaatgtac gaccaaaaag tctggctgat actgattcac taaataatgg gcatccgcaa
     7321 ataaatgcga atcagggtaa gtgtcctcac tataaaagat gccatgctga atcagtcgct
     7381 cctcctgatg ctggatgcga tcaaccaaac gattataggg ggcttgattg tacaactcgc
     7441 tgtaccagtg gtaagcggcg gctcctgttt ttccgccagc ttccttaact aattcaaaca
     7501 gcgaccactc tttggatcgc tgagcatggt aattactata gatgccattt tcataggctg
     7561 gaacgccggt catcagtact tcgtataacg gacgtgaatt gctgggcagc tcacttttta
     7621 ccttcaataa gcttgcttgc tggtgctcaa ctaaatgatt catgaaccca agctgggcga
     7681 cggctgtgtc gtagcgacag ccgtctagta taactacaat cagtttgtca agtctacttt
     7741 gcataggtca gtacctccgc ctgccaaagc tctggaagct ctacagaggt cttgttccaa
     7801 gcttcattgt cttcaactgg caccgccgct tcataagcat cctccggcag taatttttca
     7861 gctacttctt taggcagctc taccttgcga ataggtcgcg catagccctt tgccaaattg
     7921 atttgccctt catcagataa aatatattcc cgtgctagct ttgccgcatt gggatgaggg
     7981 gcatttttat tgattaaggt tgtatacccg ctaatgatgg agccgtctgt tggcacagtt
     8041 acctcaaaac gctcggagtc aatttggtca cgataattta gtccattgaa gtcccaaaca
     8101 actgccacat cgatttcacc tttttcaaga tttgctacgc tggcatcaac ggtggacaaa
     8161 cggccttttt ctgccatttt tttgtagtaa ttcagacctg gctgaatatc cttttcgtca
     8221 cctccgttgg caatcgccgc agccaataca gcaaattgtg cttggttggc aatcgtcaca
     8281 tcccccacgc taacttgata gtcaccctct tgcagctcct tccagctagt cggtgcttgc
     8341 ttcacattct ctttatcggt gataaaggaa atggttcccg tatagcttaa caaccaatcc
     8401 ccatcatcat cctttgccca atccggaatt tcctcccaat agttggtctt ataaggtaag
     8461 gttaactctt tgctttcagc caacggaccg aagctgatac cgacatcacc aatatcggcg
     8521 gttccatttt ttccttctga ttcaaactta gccaattctt ctgcactgga catatccgta
     8581 tccacgtgac ttaagccgta ttctttttca aggtcgttcc aagtgcctac ccaatttgcc
     8641 caagtatccg gcattcccaa gctggcaatc tctccttctt ccttggcttt ttctataatc
     8701 gtatctaaag agtcgtctgc cgcagccgat tgcttcgttg cttcacctga gccgcagcct
     8761 gtcagcagga tacttactgt tgctgcacaa aataaaccga tagtcatgtt acgaattttt
     8821 tcattcattt tcattcattc ttctcccctt tcgataattc cattctaaca aagctttgta
     8881 atgagagaat cagtttcttg aaaaggtttc atgaacaatg taaaggttgt atatggtttg
     8941 taaatttcga cgaattcccg ttaaccttct aaagcttttg cggtatgata gtagaaaaaa
     9001 ggaggctccc tatgcagtat tatgatcagc atctccacac gtatttttcc tttgattcag
     9061 aggaaaaatt tgaaaactat ttagcctatc agccggagtt tttcgtttct acggatcact
     9121 ttgatttaaa caatccatct accggaaaag atgacattcc ggattatcca gcctatataa
     9181 acaaactgga ctctttaaaa gaaacctatt ccaccaaatt tctgcgaggt atcgagattg
     9241 gcgttgttcc aggacaagaa gagcggatcg tggattacct cgctcagcat ccttatgatt
     9301 taaagctggt aagtattcat caaaatggcc gctttgatta tatggacgat gtggttttaa
     9361 ccaaagatcc cattcaaact accaaggaat attttgatca gatgttgcag gtcttgacgg
     9421 attttccaga aggagatatt ttgactcact ttgattatgg attacgccgc ttcaccttca
     9481 cagcggaaga attcgcggag cattttgagg ctcagctgct aacgattttc aaaaaggttg
     9541 ttgaacgaga attggcgatg gagttaaatg ccaagagctt cttgaaatac ggcaacgaag
     9601 acctttaccg ttatgccgtt cctttgtatc aaagtgtcgg cggaaagctc tttaccttag
     9661 gctcggatgc tcatgttgcc gaagattatc agctgggctt taaaaaaatg agtcagctgt
     9721 tggcagactg tcaggtagaa aagttgctag tcattcaagg aaaagaacgc cgcctgacgc
     9781 cgctgccgat tttgtgattc ctatataata gaagaaagtg gtgaaaaaaa tgagcaacct
     9841 gtgggactac aatcaagagg cacccatcca ttatttaatt gcgcgacatt gggatgcgtt
     9901 gaaaattgag gcggtttgcc gatccttgtt agcagccgtt ccaaaacaac aactggaaaa
     9961 ttttttggtg gctgacagct tgcagcggga aaaagttcag gcttattttg cagcctttaa
    10021 agatcagcct ttggaatatt tgcatgcgca gtttcatctt ttttatcaag tagccgcccc
    10081 agatgactac aacgatttac gaggacagct gcaattgacc tttcaagcgg atgaaaccgc
    10141 ctataccgtt ttattgggaa tggctcgcct tggtgatcag gcgaaggtcg agtggcggat
    10201 tttcgatatt tgatggcagg atcaaggcgt ttcagttgca aaccttcctc tctttcaatt
    10261 agaaaaaccg cagcaggaag aagtttgtgt gctggtcacc gatgctggtg aaattcgtct
    10321 ccgcttattt cctgaccaag ctcccctggc tgtagccaac tggcgctccc tagctgagca
    10381 aggcgtttat gacaacacac ctttcggctc gtgtcattaa ggaatttgtt attcaaggtg
    10441 gcgctttgga tggttctggt gatgaagctg tttccagcta tgagggcttt ttcgctgatg
    10501 aagtgcatcg cggactttat cattttaatg gcgccttggc cttaggggac cacggccccc
    10561 acaccaacgg caaccagttt tttattgtgc aaaacacaaa ggcgcaggct gacctgctaa
    10621 tgtaaagcaa gcatacttgg agcttggagg actaccggag ctggatggtc gttatactgt
    10681 ttttggacag gtataccaag ggttagaaat cgtagcagcg atcgcagctc agccgacaaa
    10741 cagtgaagat gtaccgattg agccagtgtt cattcgacaa attaacttcg aaaaaacatc
    10801 gtaaaaagac actcactgac ttcagcaaaa gctctattct tgagctggct gcagctagtg
    10861 agtgtctttc atttatccat aagataaagc ttggattcaa taaataaata aatgttttgg
    10921 ttaaagctgt gaccagcaaa tgaggaaccg tgcgagccag ttgatctgcc aatgcaaaca
    10981 tttctttagg tgaaggcgct ggcgtgtctg ccaacggata ctccagtccc aatgcttggt
    11041 aaccgtgcat accatagcag tggtacggta gtaattctaa cggtacgaac cgatcaagat
    11101 ctgccacaaa acaagcaatc gtcagcagct cggtcaggtt catattgata cctggaacca
    11161 caggaactcg aattcgcact tcgcagttag gatactcaat taaaaagcga cgaatattct
    11221 tcaaaatttg ttggttatct aagccggtcc attgtttgtg gagcttgctg gtaaacattt
    11281 ttacatccac aaacaatgta tccacatagg gagctacctt ttggatttca ttataagcac
    11341 cacaaaagct ggtttccagt acggtattga ttccaatgta tttcgatttt tgcaaaattt
    11401 ctttagcaaa atccgcctga accagtgcct cgcctccgct aatggtcact ccgccatccg
    11461 agtgaaagta aaaaacagca tccttctcaa tctcatccat tacctcttca gcggtcatgg
    11521 tctggccaaa tcctttttca atctgcttgc tttgtgattc gggaatcgaa caccaggcac
    11581 agcgtaatgg gcagcccttt aaataaacaa cggtccgtaa accagcacca tcatgtagag
    11641 aaccctgttc tattcttaat actgttcctt ccatatagat ttttgaatta cacactagtt
    11701 taaactaaaa cacacaagga aaaacttacc atttaatcat aaaattagct catataaata
    11761 tactaggatg taaaatagac tggtcaaaat ctggtcaaaa aagaggacta atacaggtag
    11821 tcctcttttt tgttatttta atattctaaa tcatttttta ttggtttatt cccttattcg
    11881 atgtagactc aaatcactat atcactagat atcaaacggc gtcatacgga atcaaaaaca
    11941 tcaaatttga cctgttaaat ggtcattgaa taacattcaa aatcaataaa acggagtcag
    12001 acacggagtc aaaaacgctg agagtaaaaa atatatacag ccttgtaggt aaagtaccac
    12061 agggctgtat attttttatt tcagattacc ttaaatgatt ccatttactt tttatctcat
    12121 tttttcctac tagttagtat caaatactct cctattttct caataaacta tttttggata
    12181 catggtatct gaaacagcta aaaccttgtc attacagcaa aaaatcacgt tatccagact
    12241 gtagacaaag tccattttat ggatgatgtc tacagtcttt tcttttataa tagatttatg
    12301 aaaacgaatg caaggagtga tagctatgat gtctaaaaac aatacgaatg gtagaaatca
    12361 atttgcgatg cttacgattg atgatctagt tcctcaagat catctcgttc gaaagattga
    12421 tgccgcgctt gattttgaat ttatttatcc aatcgtcgaa gccacttact ccgatttagg
    12481 tcgcccaagt atcgatccag tgattctgat caaattggtg tttattcagt atttattcgg
    12541 tatccgttcc atgcgacaaa ccattaagga agtcgatacc aatgtcgctt accgctggtt
    12601 tttaggctac tccttcgagg agaaaatccc ccctttctca acttttggaa agaattatgt
    12661 tcgccgattt agagaaacga cggtgtttga ggatattttt gcctatattt tagaacaagc
    12721 agttaaagca ggttttgtaa cagaggataa tttgtatctg gattctaccc acatcaaagc
    12781 taacgccaat aaacataagt ttacgaaaga aatgacccat gatgaagcga aagcctatca
    12841 ggatgaatta gaagatgaga tcaatcgtca acgaatagag gctggaaaac gcccttttac
    12901 tttggactta gaaaaggaag tgaagctgaa agaaagaaaa ataagtaaag ctgatccgga
    12961 aagcggctac tacgtcaaag gcgaacgaga aaaacaattt gcttattctg tccatacttc
    13021 atgcgacgac aatggattta ttcttagcac aatcatcact cctagaaata ttcatgacag
    13081 tcaagtcgcc tttcagctcg tcaaacaatc gaagagactt tttcctgaaa tcaattgtgt
    13141 tgtcgctgat gctgggtata agacacctaa gtttgttcac tttttgactc atttgaacct
    13201 tcgaccttgt ttgccttatt caaggcccaa agggaaaaag gagctattat caaaaaatga
    13261 gtttctctat gacgagtatt ttgattgtta tatttgtccg caagatcaaa tgctcgcttt
    13321 ttcaacggtt actcgagaag ggtaccgaga atacaaatcc aatccaaaag aatgtgtgaa
    13381 ctgtcctctg ctaaaccaat gtaccataag taaaaatcat caacgagtca tcacgagaca
    13441 tgtttgggga gatctgatgg atgaagtgga acatcttcgc ctaacagatc tgaataaatc
    13501 aatttacaaa aaacggaaac aaacgattga acgaatattt gcggatgcaa aagaaaagca
    13561 tgggatgcgt tggaccaagt atcgaggctt ggaaaaagtc gcgacgcata cgatgctagt
    13621 gtttgctgca atgaatttaa agaaattagc cacctggcta tggaaaggca aggagccttt
    13681 atttttttgt tcaaaaattc gaaacgaagt agataaaaag ctgttccaag ctcgagttac
    13741 gagtttggaa cagcttttgt ctacagtctg cgatgtcgga gacatctcgt tttctattag
    13801 gaatcaactc aggttcaaaa gaagcctccc ggtctctggg aacatcaatg tttactttac
    13861 caaagctcgt tttaagcgtc ttattgccat aaccgtttcg tcgattgtca tgtttctttg
    13921 gctctttaga atgggcgtca taccctaaat ggttattcaa ttctccttga agcatttttt
    13981 caaataaggg accaaacaca tcttttaaaa catcttgcat atcctctaca gattcgggtt
    14041 gataagtatt caaaatggat tcagctaact tctcagcatc aggatttctt ttctttctag
    14101 ccatcgtgta atcacctctt gatcttattt tagaaaaata aaaaccgtga agcaaccacc
    14161 cgcctaggat tgatggttac ttacacggtt tatattacac tctcattttt ggtgctaaaa
    14221 agcaccgaaa attttaatta ttgtcaatta ataattcttt tggattcctt cttaatatat
    14281 tgaatgaaga aataatcaat gatacaagaa gtactaaact cataaatata actacataaa
    14341 tcatgaattt aggtaataca ttgatatcta aacttgataa tgtcttgtta aatccttcag
    14401 cttctgcccc accacctaat tggctagatg cagattgttt agctatttgt ttagctatat
    14461 caccagtaac cttattcaat atattattcc caagcttgtc agctgtatat tgagctaaga
    14521 aataggaacc aacgaatgcg gggattgata taaataccat ctcaattagg aattgaccaa
    14581 aaatttctaa ttttgatata cctaatgata gtaatactgc tatttctttc tttctagcat
    14641 tcatccataa gaataataat aatgaaacta caactcctgc aaatattaat gagccaaaaa
    14701 ataatttatt tgaaattgag taaatacctg atatagattg ttgtaatgca gggtaatttg
    14761 atgaactttt aatcaaatta tattctctcc aatttatatc taatttccca agatctttta
    14821 ttacactatc aagattctta tcacctttta caaagaatgt tgcatcttgg tatacagctg
    14881 tatcttcggt attaccataa actttagcag ctgtatgaat atcagtgatt aatgtatttt
    14941 cgtatagttc ttgtgctgca cttactacac cgctattatg cccatcgaat agacctttaa
    15001 tttctacttc tactgtttca tctgcacctt tctcattatc agcatcaaat aaattagatt
    15061 ttatttttat cttatctcca actttaaggt tatttttttc agctaaatct ttatgcatta
    15121 agattttatt tttatcttca ttttctaaat gctttccttc tactaattta tatgcttctg
    15181 atacaaattt tgtttctttt gttgagtcgt taaccccagt taacataact gttcttttaa
    15241 aattctttgc tctttcaggt gattgattcg caagagtctc ttgagtttca ataatatcat
    15301 aatcaactaa atctgcaaca ctgtttattc tttttacata ggagtctata ctatctgttt
    15361 gagatatctt tttaatatct tcacctttta catttccccc acctctaggt gttcctggat
    15421 ttacttgtct atttatctcc atagaaaaac tatttgttat attagcaaat gtttcttttg
    15481 aagctctgtc cgtagcatct ttaatagata aactaatgag acttaaagtt gacatagata
    15541 aaataactaa tatgataatt aatgatttta aactttttct agttacataa gcaaatgcat
    15601 tttttatcat tattcaacct ccaaattcat tttatttact tttttcaact ttttaccact
    15661 tagttctaaa atgatatccg cagaatctgc tacttcctta ctatgtgtta caactattac
    15721 acatttattt ctatctttag ctaatgtctt taatatatta attatttctc cagcagtaac
    15781 actgtctaga ttaccagtag gctcatcagc tagtattatt ggagcatctg ataccaatgc
    15841 tctagcaata gctactcttt gttgctgtcc accagataat ttcataacat ttctttttat
    15901 ttgtttttta tctaaaccta gttcaaacaa gatactttca tctgctgatt tatttactaa
    15961 tctaatattt tcaattggtg ataaataatc tattaaatta tagttttgaa atactaaaga
    16021 tatattattt tttctatgat tactatatcc tttattttgt atatcttcat tcttaaacaa
    16081 tatttttcct gtttgaggtt tatcaagtcc agcaagtaag gaaagaagtg tagattttcc
    16141 tgttcctgac tttcctacta tcgcataaaa cttcccaagt tcaaattttt gatttactcc
    16201 tgacaaaact ttttctttag aatttgcata actatatgct acattcttta tttctaatat
    16261 atccattatt ttctcctaac ttatttttga taagatttct ttaggcttct tgattaacat
    16321 taatgaagaa gcaaatacaa ctgataaaac aataatactt attaatatta aataactttg
    16381 tccaagtgtt gttatatttg acataaaact actattattt attaaacttc caccggaaat
    16441 cattgaatcc tctgagttaa tgaatccatc tacaattact tttagtaata catttcctaa
    16501 aaataaggaa gatattatac ttggtatcga tatgaatatt aactcgaata taaattgcat
    16561 tataatttgt atcttagatg ttccaataga taagaatata cctatttcat aaattctttc
    16621 ccttaaccat agaatcaaga ttaatgaaag aacaaccatc ccacctaaca taatagaata
    16681 agtcattact tttattatat attttattcc actcactgac tctaaagact cttcaaacgc
    16741 attagaatct ttttcaacaa aatactttga ctcatcaatt ttaagctctt tcaatttgtt
    16801 taaggctaag tctgtagatt ctgcactacc agaatacatt aaaattttat ttgcaatttc
    16861 attattttct gaattattta atatctcttg gcttgttgaa taatctacaa acaccatatt
    16921 ttcactaaaa tcagaagata atcctgtata tgtttcctgt tttttaccag aaaagatccc
    16981 tataatttta aatttatgac tttttatttt tccacttttt tcaatatcta gtaattcaag
    17041 atcaacttca
//
LOCUS       DAXLPC010000061        16615 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.061, whole genome shotgun sequence.
ACCESSION   DAXLPC010000061 DAXLPC010000000
VERSION     DAXLPC010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.061"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..525
                     /gene="scm"
                     /locus_tag="ACF3UE_001892"
     CDS             <1..525
                     /gene="scm"
                     /locus_tag="ACF3UE_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFD3635279.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
     gene            complement(680..1666)
                     /locus_tag="ACF3UE_001893"
     CDS             complement(680..1666)
                     /locus_tag="ACF3UE_001893"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFD3635280.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1689..2255)
                     /locus_tag="ACF3UE_001894"
     CDS             complement(1689..2255)
                     /locus_tag="ACF3UE_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFD3635281.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2269..2685)
                     /locus_tag="ACF3UE_001895"
     CDS             complement(2269..2685)
                     /locus_tag="ACF3UE_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFD3635282.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3142..5076)
                     /locus_tag="ACF3UE_001896"
     CDS             complement(3142..5076)
                     /locus_tag="ACF3UE_001896"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD3635283.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5378..6313
                     /gene="pplA"
                     /locus_tag="ACF3UE_001897"
     CDS             5378..6313
                     /gene="pplA"
                     /locus_tag="ACF3UE_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFD3635284.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6403..7506
                     /locus_tag="ACF3UE_001898"
     CDS             6403..7506
                     /locus_tag="ACF3UE_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFD3635285.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7519..8472
                     /gene="menA"
                     /locus_tag="ACF3UE_001899"
     CDS             7519..8472
                     /gene="menA"
                     /locus_tag="ACF3UE_001899"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFD3635286.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9407..10753)
                     /gene="gor"
                     /locus_tag="ACF3UE_001900"
     CDS             complement(9407..10753)
                     /gene="gor"
                     /locus_tag="ACF3UE_001900"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFD3635287.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFCGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10887..12140)
                     /locus_tag="ACF3UE_001901"
     CDS             complement(10887..12140)
                     /locus_tag="ACF3UE_001901"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFD3635288.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(12146..13069)
                     /locus_tag="ACF3UE_001902"
     CDS             complement(12146..13069)
                     /locus_tag="ACF3UE_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFD3635289.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13290..15782)
                     /locus_tag="ACF3UE_001903"
     CDS             complement(13290..15782)
                     /locus_tag="ACF3UE_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFD3635290.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15789..16256)
                     /locus_tag="ACF3UE_001904"
     CDS             complement(15789..16256)
                     /locus_tag="ACF3UE_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFD3635291.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16392..16465)
                     /locus_tag="ACF3UE_001905"
     tRNA            complement(16392..16465)
                     /locus_tag="ACF3UE_001905"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16429..16431),aa:Arg,seq:acg)
     gene            complement(16523..16596)
                     /locus_tag="ACF3UE_001906"
     tRNA            complement(16523..16596)
                     /locus_tag="ACF3UE_001906"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16560..16562),aa:Pro,seq:tgg)
BASE COUNT         4908 a         3476 c         2956 g         5275 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagctcaga ttcatctacc
      181 actacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac atcctctacc
      241 acaagtgata gctcagattc atcaacttca agcgatagta cagacacgtc gtctaccaca
      301 agcgatacac gtcatgcaag tgtctccttc tcaaaaacaa gttcggataa caggacgaac
      361 tttaacttaa ctaataaaac aagcaatgac aatggaaaca aatcaaaaag agcacttcct
      421 aaaactggaa gtcaatcgaa taattggata acactcgcag gcgttatatt acttgtaatc
      481 ggtttaagaa tcacttttat gagttataag aaatcgaaaa ggtaaaaaaa tattcaagat
      541 aaaaaagagc aacgtcgcta acggacgttg ctctttattt ttgcttttta tcataaatac
      601 aagaactaca attcaatttg tcaaaaaaca cgtagatttc cttctgagaa atttatttac
      661 gtatcgaacc tttccctatt cagtctttgc gatccaaaat cagttgggta agggaaaaga
      721 gattctcttt tgttcgaaga gaggtggcag gtaatttctt tatttccttc aaagcctttt
      781 ctgtgtaaga ggccgctaac ttcctagctt cttccacgcc tcctgtatgt tcaacgattt
      841 tgcgtacggc gtcgacatct tcttctgtca ttgccgcttt cttctctaaa taaggtagta
      901 gctttggttt gtttttttgc aaagagtaga tcaacggtaa agaatagacc ccttgacgca
      961 tgtcttctag tacaggtttg ccgatttcct ggctctcttt tgtataatct aaaatatcat
     1021 cgataatctg aaaggccatc ccgatagaaa gtccgatatc tcctgctttt tttgcgaagc
     1081 gctcgcttgt tccactttca aaagcgccaa cagaacaact taattggaac agttcagctg
     1141 tcttacctga aatattttcc aaatattctt ttacagaaag ttcataatta tagcgatcat
     1201 ccatctgacc taattcgcca ttcaatactt tttccatact gcgagaattc aattggagac
     1261 ttttcaagga agtggagtaa tcagacaata gtttaaaaca gcagacaaat aaatagtctc
     1321 ctgcatagac agaaacgaca ttaccaaact gactacggat attaggctga ccacgtcgca
     1381 gatccgcttc atcaacgata tcatcatgga tcagtgtggc cgtatggagc atttcgatag
     1441 aagctgccaa agcgatggct ttgtctcgat cttgctctgg tccaaattgt gagaacaata
     1501 gctgataggc aggacgcaac agctttccgc cggcatggat cgtttctttg attgcttgtt
     1561 cgacaggttt gtttttcagg cggacagttt cttccatccg ttttagtgtt tctgtcaatt
     1621 ctttacttaa agcaggatag ttttcccaca ttggatgtag cttcataaaa aaactccttg
     1681 tgtgacgatt attttttggt aaacattggg ctccattttt gtttggttcc ctgctcataa
     1741 tctttttgga atcgttgaag tgtctgcaca tgtcgtaaaa gataattcgc tgcgatcccg
     1801 attgcaatcc ctgataaaat ccctaaaact gaaaggactg gcaagtacaa catgactgtc
     1861 catgattgtg caatgaaaga agccatcaaa agctgtccga cattatgcat gaaaccgccg
     1921 gccgcactaa ttccgatgat actgacacgt tttggtccta attgcttgac caataacatt
     1981 ccaaaataac taagcaaagc accactcata ctataaagga atgtggaaat cgttccgcct
     2041 agcaaagtag tcaggaatag tcgtagccaa agtagtaaga agctgtctcg ttttttcatg
     2101 gtaaaaatgg caacgatcgt gattagattg gctaagccta gttttgcacc aggcgcaaaa
     2161 gaaaaaggat aagggatcat attttccaat aaaccaatga tcactccttg tgcaacaagt
     2221 agcgaaatat aaatcatttt ttgtaattta ctcatggtgt gtgaaggtct aataaatcag
     2281 actgtcttcg tcacctccat ctgttgaacg gacttcgatc actaatttat gtggcaaaca
     2341 gacgatggtt tcgccatttt tcgttgccca gcctcgacgt acgcagatct ggtcatcgca
     2401 atctgcttct tttatccgta ctcgatcgcc atctatctcg atcaagttat aatctccgtg
     2461 ttcatctttg taagtatatg tgttgctctc ttctccagcc atcaaaggga atgttttgat
     2521 ttctgtgcca tccacacgca gtaccgcttc tttttctgct gttgcggtgt tttgctgaag
     2581 accaaaaatc atgactggta aaaaagaaag aacagtcaaa agcaaaataa taaaaacatc
     2641 ccaaggtttg agcagacttt tttcagcaaa ttctttaagg ctcatttttg ttctcctttt
     2701 tccagattaa ctcacccaat tttagcataa aaacaagagg ttgtgacacc tgtgtcttgc
     2761 tttgagtaat aagaacgaag aatagaaaac agctttccat gttttctaat tctttgggct
     2821 tattaccgag aagcagcagg tggaacaccg tttataacaa gaggttgtga cagaagtggg
     2881 caacttcaag aaataagaag gaatttacga aaattacttt tcaagttttt gtgaaatttc
     2941 ggcttatttt tcgaagaagc tacttctgga acaccgttta taacaagagg ttgtaacaga
     3001 ggttgtgaca cctgtgtctt gctcatggag gcttatctcg ggcatcttat tcctttaatt
     3061 ttacataaaa aggaggctgt gacggtttgt ctcagcccct ttctattgaa atcttgcatt
     3121 caaataacgt tctttatcta tttatttctt gccgtactgg gaacttggtc taccgtacca
     3181 ccaattacct agtgtacgtt gtagccatgg aattacccag cgatccaacc caatcgcacg
     3241 tccggaaccg ttcatcaatg cgaaagcaac aaaaatgaac caaatgttta cccagtaaaa
     3301 catgcctgat aagcagaacg tgatcaccaa tacaatcgtt gtcgcactgc atagccatgt
     3361 gaataatcca gcaatcaatg ctaatgccaa ggcaatttca aagaatacca tgaatttttg
     3421 gaagaacatt gctacatcat tgtttggcat gatcacttgc atgatctttg tgaaccagtc
     3481 tggtgacttc tcaatcacag ccattggttc ttcaccgtat gcataactca aaccaaaatg
     3541 tgcagcttga gtcgctgctt ctccggcact tgcccctgct ccgctggcag ctgtggttgc
     3601 atcaccagca gcagaagcac cactggcaac atctgttaca ttgtattccc atgtccaagg
     3661 gaacacactg tttccagtga accatgatcc ttcaccaaac caagtacttg gtttgaacac
     3721 ttcaccattc ccaatgattt ttttggaagc ttcaacgaac caaactaaac catagaaaat
     3781 acgaagtggc acactccata agacattgcc gtaacgagaa gaatgtcctc gagtcacgtt
     3841 gcgatcatct ttgatatgga aaaactcatg cattaaatat tggaacatat aataaccaga
     3901 acgaatatca aagaagtatt tcaaattcac gatatgtttc attacgatag ctaaaaatcc
     3961 gcttaaatgg atcttatcaa ataggttagc taccccccat ttggcaccaa tagaaaccat
     4021 aaatccttga tagtttcctt taaatttatg cttttctccg cctttgatcg aagccacgat
     4081 attcgctgcg gctgtgtgtc ctgtttgttc agcagcttga acgatctgcg gtgtcggtgt
     4141 tcctgggaat tcttcataaa agactaaatc accaatgata tagatgtttt tatcttcgta
     4201 gccttttgcc tgcatatatt cattggcgat caaccgctgt ccgcgtgctg attctaatcc
     4261 aaagtcagca gcgtcagaag ttcctttgac accagctgtc caaatcagtg tgtgagtcgg
     4321 aatgttgcgt ccgtctttca atttgatatg atcagcagcc acttctacga ttggtgcatt
     4381 caataataat tccacgttgt gcttacgcaa atagcgttca gcttttgcag catcatttcg
     4441 atccaacata ttcaagatcg tcggcattgc ctctacgacc atcagtgtga tttcgtttgg
     4501 atctaattta taatctttgg ctaggcgatt tttccagtcg atcagttccc caatcatttc
     4561 aataccggta aatccagaac cacagacaac gaaagtcagc atggctttac gcagttcatc
     4621 atctggttcc aatgcagctt ttgctactgt cttctcaata tgttcccgaa tccttacaga
     4681 atcttcaaat gaccaaaggg tgaatccgtg tgctttgaca ccaggtgtac caaagtcatt
     4741 cggctctccg cccattccaa ggatcagctg atcaaaagga taggaaccta atttggtctt
     4801 gacgattttt cgttctttat cgataccgat tacagtgtct gtgacaagtt gtacattctt
     4861 ttgacgagca aacaaatgct gcagatcgta ttggattgct tctggttcta cacgtccgcc
     4921 agctacttca tgcaactcgg tcatcatagt atggtacgaa tgacgatcga tcagagtaat
     4981 tgctacatct tcttttttca gtttctttgc caagtatttt gtagctgaaa caccggcata
     5041 tcctgctcct acaacgacaa tattttgctt tgccattgat catccgctcc ttatagacta
     5101 tctatataat gaatatatga taattctttt agtttgatac ttattacaca atctccatat
     5161 attatataga tgttctgttc ttttgtctaa ctccttttgg atttttttca aattttaaaa
     5221 taaagcgttt tttcacgaaa tttgctgaaa gaaaacgttt gaaatattac atgggttatt
     5281 tatcaaaaat agttgactta taggctaaaa agattagaat gtataatgaa tcacaaagaa
     5341 aaattgtgga ctagaaatgg aatggtgggg tattaaaatg aagaaaaaac gttttgtaac
     5401 tggatttgcc gtattagcat tttcagctct agtgttaggc gcttgcggcg cagatgacaa
     5461 cggaagctca aactcttctt ctgaatcatc tacagcacaa tcttcgactg caaaaagcac
     5521 aacagaatca tctgcaaaag ttgtagctgg cggagatttg caagacggca catataaatt
     5581 agaagaaaaa aattattcaa atggttaccg tgcagtcttt gaaatggttg taaaagacgg
     5641 caaaatcact gaatcaaaat atgataacgt caatgaaaac ggcgaatcaa aaacaaaaga
     5701 tgcagaatac aacaaaaaca tggaagcaaa atctggcaca aacccagaaa aatacattcc
     5761 tgagttgaat gaccaattct taaaagcaca aagcgcaagc ggtgtggaag tcgtaactgg
     5821 agctactcac tcatctgaaa gcttccaaaa ctacgcacaa caattgatcc aagctgctca
     5881 agctggtaac acagatacaa tcgaaatcga caatggtgct gatttgaaag acggcactta
     5941 caagcttgaa gaaaagaact actctaacgg ctaccgtgtg caattcgaaa tgacagttgc
     6001 tggcggcaaa gtaactgaat caaactttga ttatatcgac aaagacggta aatcaaaaca
     6061 agatgataca gaatataatg aaaatatgaa agcaaaaagc ggtacagaac caaaaactta
     6121 catccctact ctgaacgacg aattcgtcaa agcaatgggc gaagaagatg gctcacctgc
     6181 taatgtagaa gttgttacag gtgctacaca cagctcacat tcattcatca tgtacgcaca
     6241 acaattagtg aatgcagctg aaaaaggcga cactcaaaca atcgaagtag ataatatcgt
     6301 aacagaaaaa taatcacata atcatactaa taaaagttgg agggtgggac gatagccaga
     6361 ttaggcagtc gtctcacctt tcaaaatgaa gagaggaaaa agatgcggaa aaaactacta
     6421 ttttccttaa tcacactggg catctctttt atggtgctaa ctggctgcag caactcagca
     6481 aataaaacaa ccactgaaag ttcagcagct accaagatat tgaaagatcc atattctgat
     6541 gaacagttct tgttagggac ttacgttcgt atccgtgtgt atgatgaagg caaagaatca
     6601 gcattgaaac ctgccttcga tcgagtaaaa gaacttggtg ataaaatcac gatcaatcaa
     6661 aaaggttctg agatcgatga agtgaatgag caagctggga tcaaaccagt aaaagtttct
     6721 gatgacgtct acacgttagt caagcgggcc tacgaatata gccaagattc tcaaggcgga
     6781 ttcgatatgg cgattggtgc aatcacacaa ttatggcgaa tcggttttga tgacgccaga
     6841 aaaccttccc aagaagaaat cgatcaggca ttgaaattag tggattatca taagatcgaa
     6901 ctaaatgaca aagaaaaaac tgtttatcta aaagaaaaag gaatgatcat cgatttaggt
     6961 gcaatcgcca aaggttacat tacggacgaa gtagtgaaag tcttgaaaaa acaaggagtg
     7021 accactgcca tcgttgactt gggcggtaat gtctatgtct taggccacag cccaagaggc
     7081 gaaaaccaag actggacagt cggcatccaa gatccgaaca tggctcgcgg atctgtttta
     7141 ggttctatta aagaacggaa caaaacatta gttacctctg gaatttacga gcgttattta
     7201 gaagtagatg gcaaaaaata ccatcatttg tttgatccaa aaacgggtta tccgttcgac
     7261 aatgatatcg caagtgtcac gatcataaca gataaatcaa ttgatggtga cgggttgtct
     7321 acagcagtct tttcaatggg tgtgaaaaaa ggactggaat acgtcgaaag cgaattgaat
     7381 aacgggacgg aagcgatctt cgtgacaaaa gacgataaag tatatgtgac cgatccaatc
     7441 aaagacacct tcaaattatc ggaggactcc cattacacga tgggtgaccg ttctgaacta
     7501 aaataaggag tacgaaccat gacactaaaa atctttttag aagtagttga aatacgaaca
     7561 aaggtggcta gtgtatttcc ttttgcggta ggggtattat tctctatcgc tttttttcat
     7621 gagatacatt ggctaaacac ttttttattt tttattggaa tgctagtttt tgatttagcg
     7681 actaccgcta tcaataatta catggattat gaaaaggctc attctgaagt atataagtat
     7741 gaagaaaatg tcattggccg cagaaatcta tctcctgtat tgattcgaaa catgatttta
     7801 gctatgattg catttgtttt tgttatcggc gttattctaa cgatcaatac gggttggctt
     7861 ttacttttga tgggatttat ctgttgtttt attggagtat tctatacatt cggaccgatt
     7921 cctttatctc gaatgccttt aggggaaatt ttcagtgggg tgactatggg ccttggaatt
     7981 tttgccatgg tcgtttatgt caatacattc ggttcagatg tctatgatct gacagtcaac
     8041 ttttcatctg gacaatttgc tttggtagga aatctttggg ctatagcagc aatcgtatta
     8101 gcttccttac ccttggtgtt tacgattgcc aatatcatgt tggctaataa tttgcgggat
     8161 cttgaccgtg atattgaaaa tcatcgctat acactagttt tttatatcgg acgtcctgcg
     8221 ggaacagtct tattccagct attgatgtat gcttgctatt tcgtgatttt aatggggttg
     8281 ttgagcggta tctatgaatg gccgatcttg gtcaccttct tgaccttgcc aattgtgaag
     8341 aagcatttgg atcaattcaa gcaaacgtta ccccagccta tcagtttcag ctattccatc
     8401 aaaaatatgg tcttattcaa tgccagttat gtattggggc tattactaac aatcattatg
     8461 caagccattt aacagcatga agaggttgtg aaaaaactgc cctgcatcaa gtaataagaa
     8521 cagccaaata aaaatagctc cttatatttt tcgtttggtt gggcttatta ccgcagatgc
     8581 aagcttttga acaccgttta tcaggaggtt gtgaaaaagt cgcttagttt cgagtattaa
     8641 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
     8701 actggctttt gaacaccgtt tatcagaggt tgtgaaaaag tcgcttagtt tcgagtatta
     8761 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt aataccgaga
     8821 aactggcttt tgaacaccgt ttatcagagg ttgtaaaatc agtgttttgt cctgagtatt
     8881 agagaaacaa atggaaaaat agttcctcat attttgccgt tttttgagct aataccgaag
     8941 gacagctgat tgaacactat ttgttcggaa aaagtgacta actatgacac aatttttttc
     9001 acagtccctt ttttcacttg atttgattcg taccagcgaa cttgacgaga actttcttgg
     9061 tttggtaact atatggtatt cttttaacat cctcgtttgc ttcttctaat ttatttatac
     9121 aaagtcacac ttttttaaac atctgttctt cgatacattt ctatttcttt taaacatcga
     9181 taccaatatt ttgaacttaa gagtgcatac caaatggatt catttactct tcgtcagtta
     9241 cgaagataat caaaatctcc aacttcccta cttatttcgt tttgagaatt atcgaagcaa
     9301 tcttacataa ataactaaaa aacaaaaaac cagaaaatca gtatactgat tttctggttt
     9361 tacatggttt gttcaataaa aagctgttgg aactgttaat attaaattat cgcatcgtta
     9421 cgaattcttc cgctcctgtt ggatggatgg ctactgtatt gtcaaagtct tctttagttg
     9481 cacccatctt gatagccacg gcaaaacctt gcagcatctc atcgacacca acaccaatag
     9541 catgtaagcc gacgattctt tcttcttttc cgacacagat caatttcatt tcgcattttt
     9601 ggcgataatc atttaatgca aagtacattg gggtaaagcg tgaacgataa actttcaatt
     9661 cattttcgcc atatttttcc aatgcttctt cttctgtcaa accaattgtt gcaattggtg
     9721 gatgcgtaaa gacgactgtc ggaacaagtt tatagtcaag ataagaatct ttctttccat
     9781 taaataaacg ttctgataaa cgtctaccag ctgcgattgc aacaggagtc agatctaatt
     9841 taccgatcac atcaccaaca gcaaaaatat gttcatccgt tgtattttgg tatttatcta
     9901 ctttgataaa cccttttttg tccaattcca catttgtatt ttccagacct aatttttcgg
     9961 tattcggtac acgtccaccg gcaaaaagta cacaatcacc agttaaggtt tcaccatttt
    10021 caaatagcac cgtatattcg tcattgtttt tagtaatttc tttagcaata tgatgtgcgt
    10081 aagtttttat tccagcttct tggtacattt ggatcaaatt gtccgaaagc attttatcaa
    10141 acgttctaag tggtcgttct tttcgatatg cccacatgac ttcactacct aaaccacaaa
    10201 atacacctga aagttcagcc gcaatgtatc cagcacctaa aacgattgct ctcttaggta
    10261 actctgttaa ttcaaaaaat ccatttgaat caattgcgta ttctccacca ggaatggtca
    10321 ttttacttgc acggcctcca gtagcgatca agattttagg agcacgatag gtttcaccgt
    10381 ttacttcgat cgtttgacta tcgataaaag tagcgtaacc ttttatagcc tcgacatgat
    10441 tgctatctaa tcctctttga taagcaccgt gtagaaaatc aatatatttt tctcgtcttt
    10501 ctactagacc ggcgaaatca acatttttta aatctgcttg gataccgtaa cttgaggcat
    10561 ctcgttcaat tgtttccaaa atcgtacttg cttgccacat aactttttta ggtacacaac
    10621 cgacgttgac acatgttccg cccaattcat tcgcttcaat cagcaaaact tttgcgccat
    10681 gcatccctgc tctgtttgct gaagcaatac cgccagagcc gccaccaatt acgatgtaat
    10741 catatatttg cattttgttc ctccttattg aagagatcaa tcaaaacctt tatttaacga
    10801 tcctttttct acagaaaaca agtgtaacac ttttcttgaa ttttgtatgc gaagatgctt
    10861 aaaacaggga tatatcagct ttttccttat ttacgttttc ggatcatatc tccaggtttc
    10921 accggctgtg cgactggcat agttaaaatc atcattggat ttggtgctcg gtcaatggat
    10981 tcgccttctt cattatgcat aacttcaacg gtttgactga aatgactgaa tcctggacca
    11041 taaaattcga tttcatctcc tacagaaaac aagtttctct gacgtatcgt agcaatctgt
    11101 gttgcctcat cataagataa tacttcaccg acaaatttat atactgggat tttacgacgt
    11161 tcaccgaata attgttcgtt ttcagttggt gtattgtagt aaaaacctgt agctaattct
    11221 cgttgtgcta ctttccataa ctcgtcgatc cattcttgct tgcagacata gttttcagga
    11281 tcttccatat aactgtctac agccgcttta tagacatttg acaccgtaga tacataatgg
    11341 atcgatttca ttcttccttc gatcttgaag ctgtctacgc cgttttcaat caattctgga
    11401 atatgttcga tcattgacat atccactgca ctcatcgaga attcttcttc cacttcgcct
    11461 gtatcagtta aactgtttcg ttcttgacca aaaggcatat cgaacaatcc atacttccag
    11521 cgacaagatt gagaacatcc gccacggttt gcatcccgca tcgacatatg gttggacaat
    11581 gtgcatcgac cagaataaga gatacacatg gcaccatgga taaatgcttc gatttcggta
    11641 tccgtatttt tacgaatctc tgccacttcc tccattgaaa cttcacgagc taaaacgaca
    11701 cgttccaacc cttcttcttt ccagaattcc aatgtctcaa aattagttgc tgaagcttga
    11761 gtggataaat ggatcggcag acctggggct tctgtcgcac aaatttcgat caaagctgga
    11821 tcagaaacaa tcactgcaga aataccgaca tcacgcaaac tgcggaaaaa ttcccctgct
    11881 ccatcttcat ttccttcatg ggtgaccata ttagcagcaa cgtatacctt cgcatcatgt
    11941 tcttttgcaa aagcaactcc ttcagccatt tcttcataag taaaattacc tgcacggctt
    12001 cttaaaccat atgcattccc gccaatatat actgcatctg ctccataatg gatcgcggtt
    12061 tttaactttt ccagtgttcc tgctggcgct aggatttctg gtcgtttcaa ttttcttttt
    12121 actgtcattt ctttcatcat actccttatt tgatagcaga aggatcaata taaaagaatc
    12181 ctgtatctaa ttcacggttt tcaggatgca atttactgat ttcgctagtc attttttccg
    12241 ctttttcttg atcccagcta ccttctaaaa tttgtttttt tgcttcggcg aatagtcgag
    12301 tgatgtttac gaatttttcg cctggagtaa ataatccgtc caatttccat gtacagtaat
    12361 gatgctgata aagttcattc aattcattcg agagattcag atcattgctg gcaaaaatat
    12421 gtgtgccatg actatcttca taaatagaat aatgtgtctc ttctttttta ggttccgaga
    12481 taaaaagacc tctttcacga tctttttgtt cgtcttgttt cgtatagtta tagtaattct
    12541 gtagcagtgg acgtttggat tgatggatgc atgtagcacc atacacaagg gtttctacag
    12601 gaatatcgag tttttcttcc atcgccttca tctcttcaaa aggaacttca cgagcaagta
    12661 ctgctccaac tgcgcctttt ttcgcccaga aattgatttg acgtgcgctc gttactaatg
    12721 tttcagcatc ataaatatac ggtatacgca attcaggatt ttttttcatc gtataaataa
    12781 tacctgtatc accaactgtg atcacatcta cgtttatttc ttttaaaaaa gccaaatatt
    12841 caggtacatt tttcattttt tcaggatgaa tgatcccatt tacagcaata ttcgcttttt
    12901 taccatactt gtgtgctaat tctaccaatt gtcgctgttc ttctcgtgta aatgaagcag
    12961 gcagacgcaa tccaaattgc tcttcaccga aatatagtgt atctgcacct gcagcaagca
    13021 actgttctgc ttgttcaata gtttctactg tggttatgag ttcgatcata attttctcct
    13081 cctacaactt cataatagta gcatagctct aaaaactttc caatacttct tctatttaaa
    13141 gtcggatttt tgaaaattat ttcacaaaaa atcaaaataa agttcgatat attctgtcca
    13201 aatataaaaa gagattgtga caaaaatctt gtcacaacct cttaatcaag tcttactatt
    13261 ataaaaattc agctacacag gccaagtaac tatagggaac ctactgtttc ctttttaggt
    13321 ccgcgaacat tcaatgtgat cttacctttt gaagcaccta ctgttacgtg gtcacctaaa
    13381 cgaatttctc cgccaagcaa agcctcgctc aatcgatctt caatttcttt ttgaagtgcg
    13441 cgacggattg gacgtgcacc atattcagga tcaaatccag ctttcccgat cacatcgatt
    13501 gcagatggtg tgattttcac ttgaatatct tgttctttca atcgtttgat aatcgctttg
    13561 ctcatgattt ggacgattgt atggatttca tctttactca atgaatggaa gacgacagtc
    13621 tcatcgattc gattcaagaa ttcaggtcgg aaagctttct ttaactcttc taagatacgt
    13681 ttttgcatgg ctttgtgatc tttagtaaca tcttggacat tgaatccgac atttttttct
    13741 tctcgaattt gtgtcgctcc gatatttgaa gtcataatca tgattgtatt tctaaagtcc
    13801 acttttctac ctttagaatc tgttaaatga ccatcatcca atacttgcag aagtaaattg
    13861 aaaacgtctg gatgtgcttt ctccacttca tctaagagaa tcactgaata tggtttttga
    13921 cgaatttttt ctgtcaactg tccaccttca tcatacccta cgtatcctgg aggagacccg
    13981 attaatcggc ttgtactgta tttttccata aattctgaca tatcaacacg gatcagggca
    14041 tcttcacttc caaacatgac ttctgaaagt gctttggcca attctgtttt tccgacacca
    14101 gttggtccaa ggaacatgaa tgaaccaatt ggacgatcag gatctttcaa tccgcttcgt
    14161 gcacggcgga tcgcacgtga aactgctttg acagcctcat cttgaccaac gacacgttca
    14221 tgcagaagtc cttccagttc taacaagcgt tcgctttctt ttttctccaa ctgctgtaga
    14281 gggacaccag tccactccga tacaactgta gcaacatctt cttctgttac acgatcagaa
    14341 taaccttgct cctgttttgc ttcaattgca gaaacttttt gcagcttttt acgtagtgct
    14401 ttttcttgtc tgcgtaattg agcagcattt tcaaagtctt gtttttggat cgctgcttcc
    14461 ttttcttgta ctagttcatc gatttctagt ttgatcacag ttgattttgt taagtgatcg
    14521 gtttgatcca aacggacttt cgctgctgat tcatcgatca aatcaattgc tttatcgggt
    14581 agttgacgag aagtgatata acgaacagaa agattgactg ctgctcgtac agcttcatct
    14641 gtgatctcca ctccatggtg ctcttcatat cttgtacgta atccttgaag aatcacttct
    14701 gcttcttcag gagttggctc atctacttga atgcgagcaa aacgtcgctc taatgcagaa
    14761 tctttttcga tatatttttg atattcatct agggtcgttg ctccgatcgt ttgtaattct
    14821 cctcgagcta acgccggttt caagatattc gaagcatcaa ttgctccttc tgctccacct
    14881 gcaccaatta aggtatgcaa ttcatcaatg aataagatta cttgaccatc attatagatt
    14941 tcgtcgatga cctttttcat tcgatcttca aattcaccgc gatatttcgt accagcaacc
    15001 aaagatccca tatcaagcat catcaggcgc ttttcttgca tgtcttctgg cacttcacct
    15061 aaaatgattt tttgagctaa cccttcagca atggctgttt tgcctacacc aggttcaccc
    15121 accagtacag ggttattctt tgtccgtcgg ctaagaatct ggataagccg tttcacttct
    15181 ctcgaacgac caacaactgg gtccagcttg ttttcttttg ctaatttcgt caaatcacgt
    15241 gctaatgaat ctagcgtagg tgttccttgc ggtgtttgcc gtttatcttg tacatttaca
    15301 tttctacgac gattcattcc ttttccagca gaatcaccag ctagccccat tttttgtttc
    15361 agaacttgac gggcttttga aaggctgata cctaagttga tcatgattcg agtagccatg
    15421 atactttcat cttttaataa gctcatcaaa atatgttctg ttccaacttt ttgagaacca
    15481 gttttcttca cttcgctgct agctaaagca aaaacttgtt tcattcttgg tgaatatgga
    15541 agaaagactc ctttagggta agaacggata ccaccataac caatcagatg ttcaatttct
    15601 tcataaattt ccgtttcatt caaatccatt tcacgtaata cttttccagc aattccattt
    15661 tgctcgacca ctaaggctag taaaacatgt tctgaactaa ctgattgatg tttcaaccgt
    15721 tttgcttctt cttgtgcaat ttctaatact gcttgggctc tttcagtaaa aagttcttcc
    15781 atctaatctc acttcccatc ttcataactt aaacgttcca gaaatgctcg gagaatccga
    15841 gcacgtgtat gatcttcata ttcattgaaa ttcaatgtgt tttttgcaat tgcactcaac
    15901 atcaagtttc cttctttttt tgtaattatt tggtcttcat aaagtttttg aataatagca
    15961 aaagcatttt tctcactgat tgtatcatca aataactgat ttatctgctc aagtaattgt
    16021 tttttatctg aaatccttac ttttgcaatt cgtatataac caccaccacc acgtttgctt
    16081 tctactagat aaccacgttg gatggtaaaa cgggtattaa tcacatagtt gatttgtgaa
    16141 ggaacacagt taaagaggtc tgccatttca atccttcgaa tctcgatcat ttcactattt
    16201 tccagaattt tctttatata tgattcaatt aaatccgagg tattctgatg tgccatctta
    16261 ttcattccct ttgactaata ttgaccttaa ttataacgaa tttgataata gaaagaaaga
    16321 agaacgcttt ttgttaaata aatcctttag aatcaacaaa aaaaaatacg gaatatacta
    16381 ttccgtatcg acgcgcccaa gaggagtcga acccctaacc ttttgatccg tagtcaaaca
    16441 ctctatccag ttgagctatg ggcgcatatt caatttaaaa aaattataaa tcatttgaaa
    16501 acaaaaagca agataaaaaa aatcgggaag acaggattcg aacctgcgac cccttggtcc
    16561 caaaccaagt gctctaccaa gctgagctac ttcccgttta aaaaataaaa aagac
//
LOCUS       DAXLPC010000062        16009 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.062, whole genome shotgun sequence.
ACCESSION   DAXLPC010000062 DAXLPC010000000
VERSION     DAXLPC010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.062"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            304..2289
                     /gene="mobQ"
                     /locus_tag="ACF3UE_001907"
     CDS             304..2289
                     /gene="mobQ"
                     /locus_tag="ACF3UE_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
                     /protein_id="HFD3635292.1"
                     /translation="MAIFHLSMTIAKREGGKRSLIAMASYRSGEKLYSELYEKTNLYN
                     HRTVKPEAFILKPDYVPNEFLDRQTLWNKMELAEKQVNSQLCREVNVALPIELNNTDQ
                     RSLIEEFVKDNFVSEGMIADVAIHRDDENNPHAHIMLTMREVDSEGNILNKRKKIPKL
                     DENGNPILLENGKIKMVSIKTNDWDRKSLVSEIRKDWADKVNQYLKDRNIDQQITEKS
                     HAELGKKELPTIHEGFYSKKLEEKGVISELKRKNLEIQSYNDILAELDKLESQEKVLK
                     QDQNFTLKFEKTFSPLEKGELKNLSKEFKLFINDENIDKRLGELKRWENSLIFNNKME
                     IQKQRLMLSKISSERDMLTKANEILDKQAERFFKKSYPSLNIDKFSNHEVRAMVNETI
                     FRKQLLNKDQLAEVIYNERVVEKEESKKIFKEKPFQTSRYLDSKIKQVEDSITKENNP
                     ERKEILSIKKEKLIGIKQGLIEYVQSEVERKFDKNVSIDSVIEGEMLLAKADYYKTTD
                     FSKVEGVARFSSEEINSMLEQSKGFLTNIQTVKIPNDCQGVFFVQDSMKHIDELSPLA
                     KQNLKKVVNRNAYLPDSDKIELSKEIENTNKDQSQELDKDVPEKNEVTVKMFQFAKSI
                     NRLLSGNQLQKKRNLDKLIKQTKAKENQSLQRNIPLR"
     gene            2313..2645
                     /locus_tag="ACF3UE_001908"
     CDS             2313..2645
                     /locus_tag="ACF3UE_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CagC family type IV secretion system protein"
                     /protein_id="HFD3635293.1"
                     /translation="MKKFIKDTKFKLGSAVVALGTLFITDPVFAATDPQAKLVQAGNT
                     IKGVLTALIVVVGGIACAKIVIKYLPSIDDPQEKNTMYKALGTALLVTALGGALVWLV
                     PWAYGLLA"
     gene            2664..3047
                     /locus_tag="ACF3UE_001909"
     CDS             2664..3047
                     /locus_tag="ACF3UE_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3635294.1"
                     /translation="MNSDQVKQALLDLLNADTEKGRTWFFPSNVSDRYTVILGLDLKQ
                     SAKAIGTALISVLLAILIFRSTAVFPLIIYVIVGLVSFGGVWAFYTIKPITDRPNISI
                     SDFMKQRKDFSKRPKVYYKKPKERV"
     gene            3064..3693
                     /locus_tag="ACF3UE_001910"
     CDS             3064..3693
                     /locus_tag="ACF3UE_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635295.1"
                     /translation="MFDFLKKSSKSNDNKKSDTIKEMIYWEDSSRFQGVFKDFFVVYQ
                     PEKKQFSLVSMLKVDGLNVDTLPVSEQEGLNEDFGVFLSQNVLYEPQITSKNVPVEID
                     DFVEAWGNTVENYRKMPGHNEALLQLKASYYYHYRNLASNMETSKKQHFVINSEPISK
                     ETYDSLELSYQVLRDKTRTIRTALIAFLSKYDCQVEICTIGEMKKVLNS"
     gene            3704..5665
                     /locus_tag="ACF3UE_001911"
     CDS             3704..5665
                     /locus_tag="ACF3UE_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion system protein"
                     /protein_id="HFD3635296.1"
                     /translation="MEKIPKEKIIVIPEVDTDVVSDLAPFNFTVERDKLLIDDSYAVP
                     YVITKYNNKPRGNWFNRIRKMSGDITISHYYTKANGNSLNDYYNRTIKNKQAEIDRSH
                     DPLTIIRLEREMKIAQTQLEQAVDENTSYLYLYTYVLIKSKSEDKLKKLCEDFETRCI
                     ASGVKALIPYTMIDKAYWSALPLQSNEVPEYTYTIANSISASSIFPFDDNELSVFTKN
                     MIIEGINKDTENIVSIDYTNRKLVVNRNKFVFGLSGGGKTTYLTSDYLKKYAFADNST
                     ELKHRIVLFDPEDEQTERVRSLGGEIINLSSMSDVRINPFQIYSRNTPDVDLKESLSD
                     FEEDELVENLEIKHKDFEMTENDIDKEISKRMNILTPYFLMVDHSLTDSQLSIIKLEA
                     KKCYTTLYEKKNLSKMENTDFPTFSDLESRLKALEETDPKRYKRIEDFIYSLEDFTIG
                     SRTIFNGHTNIDLSNPLICFSLRDLQTEEGIRDLAYLNSFSYLFEEITNNPQIVTSVY
                     ADEFHFLLKNKISADFFFQAYKRFRKYNADCTVSTQQIDDVLKAPDNIGKAIIGNSFT
                     KVFFGLDETEAQGISNELKLKLTKKELSFITSKRQGEALLFHGTKRAKIKVDLTQEEM
                     RLLNPGGYEDIYGVSPKKEINWLLRSKIQ"
     gene            5679..7031
                     /locus_tag="ACF3UE_001912"
     CDS             5679..7031
                     /locus_tag="ACF3UE_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /protein_id="HFD3635297.1"
                     /translation="MKYKILKNLQFYYQENVIVVQINEKYLTNREHIFDVEESEQYFV
                     DVEEILTKDGKLEIVYHRPNGYTPLLDLKEYADFYKLDIVNRLLEMNVLEKTNTYLAM
                     QNILLKDTRDLLFIYKADHFGNLPYSTKEELEQWKNFICSFFGKFSLEKYEKNRIEIL
                     TKEKNSFLNDVEAVESLESLRDLIKNRLTEEQKNFFSAELQDKKANVRKIRRNKSLKI
                     ALVVGVIALYGGTVFLMKVNEKKQVTATQQSAETEITILNKIIDNDSENIEEDMQKLN
                     YPKKKQVDIYVKLGDYTKAYELDKKSDKKIIQSLYKQGETEKIENLDLPGSDYLADFK
                     KILAYDNSTDIEYLVQTSTDTTIVEALIDQAVKKKDIPTVKNIRQVSITQKKLAIDPK
                     RQISMIDLLIENNSEELENIYKDNSLNDDLKKKQTNDLLEENNTLLSEKIELTNAEKD
                     "
     gene            7053..8162
                     /locus_tag="ACF3UE_001913"
     CDS             7053..8162
                     /locus_tag="ACF3UE_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFD3635298.1"
                     /translation="MGATAAKLLIRYRKPIAKAILGFFVFIIVIFLLIFNNDQTAPSG
                     GLATENKNLSESVLRYKSTVEKYARQYDGMEYVPYILALMQIESGGNGGDPMQSSESL
                     GLPPNTIQDPERSIQRGVEFFVENMKSAINRGSDIKTALQAYNYGGGFVDFVVKNGGT
                     YSFELAKQFSINMSGGEKVPYVNALSTSMGYNYRYNYGNMFYVPKLLEYVNESQASAE
                     GVQNNSNNTGAVQVDVPSEYKNKLRYPRYDGHNYNTSGSYPFGQCTWYAFNRMAQIGK
                     PVDDFMGNGGEWGYKGKALGYKVTNKPKVGTAISFPPGSFGSDPVYGHVAFVEVVNAD
                     GTLLVSECNVVNPGSGTISYRVVPASIANIASYVE"
     gene            8175..8726
                     /locus_tag="ACF3UE_001914"
     CDS             8175..8726
                     /locus_tag="ACF3UE_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635299.1"
                     /translation="MEFDKIKVSLFISTLALLVVTIGMIVFGIKQGEQIRHLKSDLKS
                     VQTELADKQAEQNTNQSESEKIIKEFYKTVYNYEKSQKEISMTTVKELATDNVYQELQ
                     NEINVNNSYSPQQNTIQKSSVNENEIKILAYASKDNSQQYLVTAPIHQVFNGTKNDFE
                     INQIIQIKNQQITQRTTIQLGEE"
     gene            8731..9162
                     /locus_tag="ACF3UE_001915"
     CDS             8731..9162
                     /locus_tag="ACF3UE_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635300.1"
                     /translation="MAKKKQEQVKLIILVILYLLLLPVTLIVFKLLPFIIANDTNIEL
                     STFVTTILKHPINTFLEIIQSNYMIPFFIVQIIVLIILFVFLHPTKRQPFEVVGKTNP
                     VHGSAYWGEESEINAPKNVHLIPEKSMKKILEKSMRRGKNE"
     gene            9155..10810
                     /locus_tag="ACF3UE_001916"
     CDS             9155..10810
                     /locus_tag="ACF3UE_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFD3635301.1"
                     /translation="MSSLLAESDGLILGKFQSGNVVIQPEDSKISNRNIFVVGGPGSF
                     KTQSYVLPNVVNNRSTSIVVTDPKGEIYELTNEIKKAQGFKTVVINFKDFLLSSRYNP
                     LLYIRKSNDTNKIANVIVSAKNDPKRKDFWFNAQLNLLNTLIKYVYFEYEPSARTIEG
                     ILDFLEEFDPRYNEEGVSELDEQFERLPDGHEAKRSYYLGFRQAQSEARPNIVISLLT
                     TLQDFVDKEVAEFTSTNDFFFEELGTSKICLYVLISPLDRTWDGLVNLFFQQMFTELY
                     FLGDKHNAKLPVPLVMLLDEFVNLGYFPTYENFLATCRGYRISVSTILQSLPQGFELY
                     GDKKFKAIIGNHAIKICLGGVEETTAEYFSRQVNDTTIKVYTGGTSESKTSAKTTNRS
                     GSKSESYGYQKRRLITEGEVINLQQEENGRKSIVLIDGKPYMLRKTPQFELFGNLLKK
                     HEISQQDYISSQTEFAKEYIEELEVQHKQRKVQLASAPVFHEKKQENDLNKKEIKLPE
                     QPIESEVTEEVEEKEQLMSDILSSFDEGIEENTTNNDNSELPF"
     gene            10828..11751
                     /locus_tag="ACF3UE_001917"
     CDS             10828..11751
                     /locus_tag="ACF3UE_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635302.1"
                     /translation="MNGLKEFFGNIPMFQKQVEREIEEKGIKPSEGIKKMEFSRQVLR
                     NIVIGVLFIGILAFVGISYFNNKNQPPVAPTATTTSKESNQSEASGEATENSSQAVQG
                     SSDHLLKLSAKERADEATEAFESWYKSFSKGDVILEINKELLKEGSGGTSPIELQTKL
                     IDNLKAKFGDKVSDDFYSGLQASFNFNPVIVDGTKGLTISKQNDDQSQWLRTWFLDTE
                     KTAQNTKIILRNDFSYEWADWRNKGQHDEKVGSMFTQIDWANDLRYEVIGIVTSKQEK
                     NIENIGGVFVVMQYNEKIGKWQVSGTIGGVM"
     gene            11753..12685
                     /locus_tag="ACF3UE_001918"
     CDS             11753..12685
                     /locus_tag="ACF3UE_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL family protein"
                     /protein_id="HFD3635303.1"
                     /translation="MDVIDQIKETGSDILSSAGDAISGIFEGVKESVDSVLHPIDSLL
                     GSWGSDLLEASMKIANKTTFDIPNIKLISTITNVFVFATTTFAICIVLYKVIEAQIQA
                     SNGSGDALTANIVQKLFYSSIALATLPWAMNFFIKKIVAPIGEYVIQQVANDLNVETI
                     GERLRNFLVSNFFNGGVSAVVLFVFVIFFAFSIAKYFVAICVFYADFLVLTMLTPLVA
                     LSLLTDEQNYFQIWIKELLSEALTMLIKLILYLLMITLMIAEKYTLPNFMLMVGCGLL
                     IIKTPSALQNMWYSTKVSKGGGLGNLAMMAMFRK"
     gene            complement(12812..13999)
                     /locus_tag="ACF3UE_001919"
     CDS             complement(12812..13999)
                     /locus_tag="ACF3UE_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFD3635304.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            14322..15290
                     /locus_tag="ACF3UE_001920"
     CDS             14322..15290
                     /locus_tag="ACF3UE_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635305.1"
                     /translation="MSYYFEIRIILPEEEKQFLNRKLSKSELSEVTHYLQQKTSRGIP
                     VKFRVGIFRVEDQTKIMSVTLNTKNTKETDVINLLLNRVTDQHVLVYLNEPTEPTLNT
                     QELNRQELKTSNERQEIPQTEIPTETVNEPSVIKEISKKNQAKQTNSRKESLSESITK
                     KNVPKIHLFISILTLFIVLLIGISVIQQVQLQSVKKESELLKEQIERVKETDISQSKI
                     DTFGRYFLTYYFSQEKNQENYQSSLRTYVSEKVDIADWKALEKMLKSVNYYGSEQTKK
                     GYSVEYLLNVSVDNRSKMQKITFEVEPTKNGFLVTTQPKLTDFSFN"
     gene            15319..15687
                     /locus_tag="ACF3UE_001921"
     CDS             15319..15687
                     /locus_tag="ACF3UE_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635306.1"
                     /translation="MGKINLNQIYTAKEMSERIGKNRNYLSQAYRNNKHEILKNFNYR
                     KIGGTIIFSDNPNNDLSQLITAKEASQLLGKNDEYFAHIYKRFPHRLEGIDHIYTGKT
                     LFLTKESLEAFKKKMNGNVR"
     gene            15747..>16009
                     /locus_tag="ACF3UE_001922"
     CDS             15747..>16009
                     /locus_tag="ACF3UE_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFD3635307.1"
                     /translation="MKKLALLTLFSTALLVSAPLVSFADETASSSDVTILADDNPVVP
                     VEPTDPTTPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPV"
BASE COUNT         6011 a         2506 c         2932 g         4560 t
ORIGIN      
        1 ttgattttcc atgaaatacg cctcctaata tattatgtaa ctctatcata ttatattatt
       61 tttctaaaat caataaatat aaatgaaaat gtcagattaa acatatttac ttttataatg
      121 ataagtggta aaattaattt atcaaggatt cccttagatg atttactaag ggcgcactta
      181 tacccctaaa tttcatttag tggtaattgt gctataaaac ttaatttaca tttcgtttta
      241 tcgtcaagcg tgtttgttaa aattcgctac gctcatgttt gaaaagaaag agaggtgata
      301 caattggcaa tcttccattt atctatgaca atagcaaaaa gagaaggcgg aaaaagaagt
      361 ttaattgcaa tggcttctta tcgaagcggt gaaaaattgt atagtgaact atatgaaaaa
      421 actaatctat acaaccatag aactgttaaa ccagaagctt ttattttaaa gcctgattat
      481 gtacctaatg aatttttaga tagacagact ttatggaaca aaatggaatt agcagaaaaa
      541 caggtgaatt ctcaactttg ccgagaagta aatgtagcat tgccaattga attaaataat
      601 acagatcaac gatcactgat agaagaattt gttaaagata attttgtcag cgaaggaatg
      661 attgcagatg tagctatcca tagagatgat gaaaacaatc cccatgctca cattatgcta
      721 acaatgagag aagtagatag tgaaggaaat attcttaaca agcgaaaaaa gatacctaaa
      781 ctagatgaaa atggaaaccc gattttatta gaaaatggta aaattaaaat ggtttctatt
      841 aaaacaaatg attgggatag aaaatctctt gtttctgaaa ttcgtaaaga ttgggctgat
      901 aaagtcaacc aatatttaaa agatagaaat atcgatcaac aaattacaga aaaatcgcat
      961 gcggaacttg gaaaaaaaga actaccaaca attcatgaag gtttttactc aaaaaaatta
     1021 gaagaaaaag gagttataag tgagttaaaa agaaaaaatt tagaaattca aagttacaat
     1081 gatattctag ccgaacttga taaacttgaa agtcaagaga aagtgttaaa acaagaccaa
     1141 aacttcactt taaaatttga aaaaactttc tcacctttgg aaaaaggaga actgaaaaat
     1201 ctttcaaaag aatttaaatt atttattaat gatgaaaaca ttgataaacg attaggtgaa
     1261 ttaaaacgat gggaaaattc acttatcttt aataataaaa tggaaattca aaaacaacgt
     1321 ttgatgttaa gtaaaattag tagtgaacga gatatgctta caaaggcaaa tgaaatttta
     1381 gacaaacaag cagaaagatt cttcaaaaaa tcttatccaa gtttgaatat tgacaaattt
     1441 tcaaatcacg aagttagagc aatggttaat gaaaccatat ttagaaaaca gttattgaat
     1501 aaagatcagt tagcagaggt catttacaat gaaagagtag tagaaaaaga agaaagtaaa
     1561 aagattttta aagaaaaacc atttcaaact agccgttatc ttgattcaaa aattaaacaa
     1621 gttgaagata gtataacaaa agaaaataac cctgaaagaa aagaaatttt atcaattaag
     1681 aaagaaaaac taataggaat aaaacaagga ttgatagaat atgttcaatc agaagttgaa
     1741 agaaaatttg ataaaaatgt ttcaatagat tcagtcatag aaggcgaaat gttacttgca
     1801 aaagctgact attacaaaac aactgatttt tctaaagtcg aaggagttgc tagattcagc
     1861 agtgaggaaa ttaattccat gttggaacaa tcaaaaggct tcttaactaa tattcagacg
     1921 gtgaaaattc ctaatgattg tcaaggtgta ttttttgttc aagatagcat gaaacatatt
     1981 gatgaactaa gcccattagc aaaacaaaat ctgaaaaagg ttgttaatcg caatgcttat
     2041 ttacctgatt ctgataagat agaattaagt aaagaaattg aaaataccaa taaagatcaa
     2101 tcccaagaat tggataaaga cgtaccagaa aaaaatgaag tgactgtaaa aatgttccaa
     2161 tttgcgaagt caattaatcg tttgttgagt ggtaaccaac tacagaaaaa acgaaaccta
     2221 gacaaattga ttaagcaaac aaaagcaaaa gaaaatcaat cattacaaag gaatattcct
     2281 ttgcgataaa ataaaaacaa gaggtgtata aaatgaaaaa atttatcaaa gatacaaagt
     2341 ttaagcttgg aagtgcggtt gttgcgttgg gtacattgtt tattactgat ccagtgtttg
     2401 cagccactga tccacaagcg aaattagttc aagcgggtaa cactataaaa ggtgttttaa
     2461 cagccttaat tgttgtagtt ggtgggattg cttgtgcgaa gattgttatt aaatacttgc
     2521 cgtctattga tgacccacaa gaaaaaaata ccatgtataa agccttggga acagccttgc
     2581 ttgttacggc attaggtggg gcgttggttt ggttagtacc ttgggcgtat ggcttacttg
     2641 cttaatagag aagggagtta gttatgaata gcgatcaagt gaaacaagcc ctattagatt
     2701 tgttaaatgc agacactgaa aaagggcgga cttggttttt tccgtccaat gtatctgatc
     2761 ggtacacagt cattttaggg ctagatttaa aacaatcagc aaaagcgatc ggtacggcat
     2821 taataagcgt gctattggca attcttattt tccgtagcac agccgttttt cctttaatta
     2881 tctatgtcat tgttggtttg gtgtcatttg gtggtgtatg ggcgttttat acgattaaac
     2941 caattacaga ccgacctaac atttctatat ctgattttat gaagcaaaga aaagactttt
     3001 ctaaaagacc aaaagtctat tacaaaaagc caaaagaacg agtgtaaaag agaggtgatt
     3061 tcattgtttg attttctaaa aaaaagttcc aaaagtaacg ataataaaaa aagcgatacg
     3121 ataaaagaaa tgatttattg ggaagatagt tcccgatttc aaggcgtttt taaagacttt
     3181 tttgtcgttt atcagccaga aaaaaagcaa tttagccttg tgagtatgct aaaagttgac
     3241 ggcttaaacg ttgatacatt gccagtatca gagcaagaag ggttaaacga agattttggt
     3301 gtctttctat ctcaaaacgt tctatatgaa ccgcagatca cttctaagaa tgtaccagta
     3361 gaaattgacg attttgtaga agcctggggg aatacagtag aaaattatcg caaaatgcca
     3421 gggcataacg aagctttatt acaactaaaa gctagctatt attaccatta cagaaattta
     3481 gcaagtaaca tggaaacttc aaagaaacaa cattttgtaa ttaattctga accaatttca
     3541 aaggaaacat acgacagttt ggaattgtct tatcaagtgt tacgtgataa gacaagaaca
     3601 atcagaacag ctttaattgc atttttaagt aaatatgatt gtcaggttga aatttgtacg
     3661 attggcgaga tgaaaaaggt tttgaatagt taggagcgtt aaaatggaga agataccaaa
     3721 agagaaaatt attgtaatac ccgaagttga tacggacgtt gtatctgatt tagcaccatt
     3781 taactttaca gtagaacgtg acaaattatt gattgatgat tcatacgcag ttccctatgt
     3841 cattacaaaa tacaataata aaccaagagg aaattggttt aatcgtattc gtaaaatgag
     3901 tggagatata accatatctc attattacac taaagcaaac ggtaactcat tgaatgatta
     3961 ttacaacaga accattaaga acaagcaagc agagatcgat cgttcgcatg atccgttgac
     4021 gattatccgt ttagaacgtg aaatgaaaat tgcacaaacg cagttagaac aagccgttga
     4081 cgaaaacact tcttatcttt atttatatac ctatgttttg atcaaaagta agtccgaaga
     4141 taaactgaaa aaattgtgtg aagattttga aacacgttgt atcgcaagtg gagtaaaagc
     4201 cttgattcca tatactatga ttgataaagc gtattggagt gccttacctt tacaatctaa
     4261 tgaagtgcct gaatacacgt acacaatcgc taattcaatc agtgcaagca gtatttttcc
     4321 ttttgatgat aatgaattaa gtgtatttac taaaaatatg attattgagg gaattaataa
     4381 agatactgaa aatatcgtta gtattgatta caccaacaga aaattagtag tcaatcgtaa
     4441 taaattcgtt tttggtttat ctggtggggg aaaaaccact tacctaacgt cagactattt
     4501 gaaaaaatat gcttttgctg ataactcaac agaactaaaa cacagaattg ttttatttga
     4561 tcccgaagat gaacaaacag aacgtgtacg ttctctaggg ggcgaaataa tcaatctttc
     4621 gtctatgtca gatgttcgta tcaatccgtt tcaaatctac tcacgcaata caccagatgt
     4681 ggatttaaaa gaatcgttat ccgattttga agaggacgaa cttgtagaaa atcttgaaat
     4741 aaagcacaaa gattttgaaa tgactgaaaa tgatattgat aaagaaatca gtaaacgaat
     4801 gaatatttta acgccatatt tcctaatggt ggatcactct ttgactgaca gtcaattatc
     4861 tattattaag ttagaagcga aaaaatgcta taccacttta tacgaaaaga aaaacttgtc
     4921 aaaaatggaa aacaccgatt ttccaacatt ttcagactta gaaagtcgat tgaaagcatt
     4981 agaagaaact gatcccaaac gatacaagcg aattgaagat tttatttatt cattagaaga
     5041 ttttacaatc ggaagccgta ccatatttaa cggtcataca aatattgact taagcaatcc
     5101 gttaatttgc ttctctttgc gagatttaca gaccgaagaa ggaatcagag atttagcata
     5161 cctcaacagc tttagttatc tatttgaaga aataaccaac aatccgcaaa ttgtaacgtc
     5221 tgtttatgca gatgaatttc actttttact gaaaaataaa attagtgcag attttttctt
     5281 ccaggcttac aaacgcttta gaaaatataa cgccgattgt accgtatcaa cccaacagat
     5341 tgatgatgta ttaaaagcac ctgataatat cggtaaagca attattggga atagctttac
     5401 aaaagtgttc tttggacttg atgaaacgga agcgcaaggt atctcaaacg agttgaaact
     5461 taaacttaca aaaaaagaat tatctttcat tacctcaaaa cgtcaagggg aagctttact
     5521 ctttcatgga acaaagaggg ctaaaattaa agtcgatttg acccaggaag aaatgcgttt
     5581 gcttaaccca ggcggatatg aagatattta cggcgttagt ccgaagaaag agatcaattg
     5641 gttgttaaga tcgaaaattc aatagaaggg agaaaaaaat gaaatacaaa atcttgaaaa
     5701 atttacaatt ctactatcaa gagaatgtca ttgtcgtcca aataaacgaa aaatatttga
     5761 cgaatcgaga acatattttt gatgtagaag aaagtgaaca atattttgtt gatgtcgagg
     5821 aaattttaac caaagacgga aaactagaaa ttgtttatca ccgtcctaat ggctatacac
     5881 cactacttga tttaaaagaa tatgctgatt tttataaatt ggatatagtg aatcgattac
     5941 ttgaaatgaa tgtactagaa aaaacaaaca cctatctagc aatgcaaaat atcctactca
     6001 aagatacacg tgacttgctt tttatttata aagcagatca ttttggtaat ttgccttact
     6061 caactaaaga agaattagag cagtggaaaa attttatttg tagttttttt ggtaaatttt
     6121 cgcttgaaaa gtatgagaag aatcgtattg agattctaac aaaagaaaaa aattcatttt
     6181 taaatgatgt agaagcagtt gaaagtttgg aatcattaag agatttaata aaaaatcgac
     6241 taaccgaaga acaaaagaat ttcttttctg ctgaattaca ggataagaaa gcaaacgtcc
     6301 gaaaaattcg cagaaataaa agcttaaaaa ttgcgttagt tgtaggtgtt attgcgttat
     6361 atggcggtac ggtttttctt atgaaagtaa atgagaaaaa acaagttacg gctacacagc
     6421 aaagcgcaga aacagagatc actattttaa ataagattat tgataatgat agtgagaata
     6481 tcgaagaaga tatgcaaaaa ctcaactatc ctaagaaaaa acaagttgat atttacgtga
     6541 aacttggtga ctacactaag gcttatgaac ttgataaaaa gtcagataaa aaaattattc
     6601 aaagtctgta caaacaaggg gaaaccgaaa aaatagaaaa tcttgatttg ccaggaagcg
     6661 actatttagc agacttcaaa aagattttag cgtatgacaa ttcaacagat attgagtacc
     6721 tggttcagac aagtaccgat acaacaattg ttgaagcttt aatcgatcaa gcggtaaaga
     6781 aaaaggatat tccaacagta aaaaatattc gtcaagtatc aattacacaa aagaaattag
     6841 caatcgatcc taaacgtcaa atcagcatga ttgacttatt gattgaaaat aacagtgaag
     6901 aactagaaaa tatatataag gataattctt taaatgacga cttgaagaaa aaacaaacca
     6961 atgacttgtt agaagaaaac aacacattgc ttagtgaaaa gattgaatta acaaacgctg
     7021 aaaaagatta ggaaggttgg tgatttcata tcatgggagc aacagctgct aaactgctta
     7081 ttcgttatcg aaaaccgata gcgaaagcaa ttttaggctt tttcgtcttt atcattgtaa
     7141 tcttccttct tatttttaat aacgatcaaa ccgcccctag tggcggacta gcaacagaaa
     7201 acaaaaattt aagtgaatct gttttgaggt acaaaagtac cgttgaaaag tacgctagac
     7261 aatatgacgg tatggaatat gtaccttata tcttagcact catgcaaatt gaatcgggcg
     7321 ggaatggtgg cgatcctatg caatcaagcg aaagtttagg attgccccct aacaccattc
     7381 aagaccccga acgaagcata caacgaggag tagagttttt tgtagaaaat atgaaaagcg
     7441 ctataaaccg aggatcagat ataaaaacag ctcttcaagc gtacaattat ggcggtggtt
     7501 ttgttgattt tgtagtgaag aatggcggaa cgtattcttt tgagttggct aaacaatttt
     7561 ctattaatat gtcaggtggc gaaaaggtac cttatgtaaa tgctttatct acttcaatgg
     7621 gctacaatta ccgctataac tacggaaata tgttctatgt gccaaaatta cttgaatacg
     7681 ttaacgaaag ccaggcaagc gcagagggcg ttcaaaacaa ttctaataat actggcgctg
     7741 ttcaagttga tgtacctagt gagtacaaaa ataaattacg ttatccaaga tatgacggac
     7801 acaactataa cacaagcggt agttatccat ttgggcaatg tacttggtac gcttttaatc
     7861 gtatggctca aataggaaaa ccagttgatg attttatggg caatggtggc gaatggggct
     7921 ataaagggaa agctttaggc tataaagtaa caaataagcc caaagtaggt acggcaattt
     7981 ctttccctcc aggttctttc ggttctgatc cagtttacgg acacgttgcc tttgtagaag
     8041 tcgtaaatgc agacggtacg cttcttgtat cagagtgtaa tgtagtaaac ccaggaagtg
     8101 gaacaatcag ttatcgagta gtgccagctt ctattgcaaa cattgcaagt tatgttgaat
     8161 aaggagagaa aaaaatggag tttgacaaaa taaaagttag tttgtttatc tcaacgcttg
     8221 ctttacttgt ggttaccata ggcatgattg tttttggaat aaagcaaggc gaacagatcc
     8281 gtcacttaaa aagtgattta aaaagcgtac agacggaact agcagacaaa caagcggaac
     8341 aaaacactaa ccaaagcgaa tcggaaaaaa ttatcaaaga attttacaag accgtttata
     8401 actacgaaaa aagccaaaaa gaaatatcta tgacaacggt taaagaatta gcgacagaca
     8461 acgtttatca agaattacaa aacgagatca acgtaaacaa ttcatatagc ccacaacaaa
     8521 acacgattca aaagtcttca gtaaacgaaa atgaaataaa aattcttgct tatgcaagta
     8581 aggataattc acagcaatat ctagtaacag caccgattca ccaggttttt aacggtacaa
     8641 aaaatgattt tgaaataaac caaattatcc aaattaaaaa ccaacaaatt actcaaagaa
     8701 cgaccattca attaggagag gagtagaagc atggcgaaga aaaagcaaga gcaagtaaaa
     8761 ctgattatcc tagttatact ctatctacta ttattaccag taacattgat tgtgtttaaa
     8821 ttattacctt ttatcattgc gaatgataca aatattgaat tgagtacctt tgttacaact
     8881 attttaaagc acccgatcaa tactttttta gagatcattc aatctaatta catgattccg
     8941 ttcttcattg tacaaatcat tgttttaatt attttatttg tctttcttca ccctaccaaa
     9001 cgccaaccgt ttgaggttgt cgggaaaaca aaccctgttc atggatcggc ttattggggg
     9061 gaagaatcag aaataaacgc accaaaaaat gttcatttga tccctgaaaa gtcaatgaaa
     9121 aagatattag aaaagtcaat gaggaggggg aaaaatgagt agtttgttag cagaatcaga
     9181 cggtttaatc ttagggaaat ttcaaagcgg aaatgttgtg atccaacccg aagatagcaa
     9241 aataagcaat cgaaatattt ttgtagtagg tggtccagga tcatttaaaa cacaaagtta
     9301 tgttttgcct aatgttgtaa ataatcgcag tacgtcaatt gttgtaaccg atccaaaagg
     9361 ggaaatttac gagttaacca atgaaataaa aaaagcccag ggcttcaaaa cggttgtcat
     9421 aaattttaaa gattttctac taagttctag gtacaatcca ttactttaca ttcgcaaatc
     9481 aaatgataca aacaagattg cgaacgtcat agtatcagca aagaatgatc ccaaacggaa
     9541 agatttttgg ttcaatgcac aattaaactt attaaataca ctgattaaat atgtttattt
     9601 tgaatatgaa ccaagcgcaa gaacaattga gggtatttta gactttttag aagaatttga
     9661 tccacgctat aacgaagaag gtgtatcaga acttgatgaa caatttgagc gtttgccaga
     9721 cggacacgaa gcaaaacgca gttactattt aggcttccga caagcacaaa gtgaagcaag
     9781 accaaacatt gttattagtc tattgacgac tttacaagat tttgttgata aagaagtagc
     9841 agaatttacc agtacaaacg attttttctt tgaggaatta ggaacgtcaa aaatttgttt
     9901 atacgtgcta atttccccat tagatcgaac ttgggacggc ttagtgaatc tctttttcca
     9961 acaaatgttt acagagttat attttttagg ggataagcac aacgcaaaat tgccagtacc
    10021 tttagttatg ttactagatg aatttgtcaa tttgggctac tttccaacat acgagaattt
    10081 tcttgcaaca tgtcgagggt atcgtatttc agttagtacc attttacagt cattgcccca
    10141 aggctttgaa ctatacggag ataagaaatt taaagcgatc attgggaatc atgccattaa
    10201 aatttgtcta ggtggtgtag aggaaacaac cgctgaatac ttttcaagac aagtaaatga
    10261 tacaacaatc aaggtatata caggcggaac aagtgaaagt aaaacgtccg caaaaacaac
    10321 taaccgaagc ggaagtaagt cagaaagcta cggttaccaa aaaaggcgat taattaccga
    10381 aggggaagtt atcaatttac aacaagaaga aaatggaaga aaaagtattg tgttaattga
    10441 cggtaaacct tacatgttaa gaaaaacgcc acaatttgaa ttgttcggaa atcttcttaa
    10501 aaagcatgaa atttcacaac aagattatat aagcagtcaa acagaatttg ccaaagaata
    10561 cattgaagaa ttggaagtac agcacaagca aagaaaagta caactcgcaa gcgccccagt
    10621 ttttcatgag aagaaacaag aaaatgactt aaataaaaaa gaaatcaaat tacctgaaca
    10681 accgatcgaa tcagaagtaa cagaagaagt agaagaaaaa gaacaattaa tgagtgatat
    10741 tctaagtagt tttgatgaag gtatagagga aaacacaacc aacaatgaca acagcgaatt
    10801 accattttaa agatcggagg aaatcaaatg aatggattga aagaattttt tgggaatatc
    10861 ccaatgtttc aaaaacaagt tgagcgagaa atcgaagaaa aagggattaa acctagcgag
    10921 ggtattaaaa aaatggaatt tagccgtcaa gtgcttagaa acatagtgat tggtgtcttg
    10981 tttattggca ttcttgcctt tgttggtatt tcttatttta acaataagaa tcaaccacca
    11041 gtagcaccaa ccgccaccac cacaagcaaa gaaagtaacc aatcggaagc aagcggagaa
    11101 gctacagaaa acagctcaca agccgttcaa gggtcaagcg accatttact caaattaagt
    11161 gccaaagaac gagcagacga agcgacagaa gcttttgaga gttggtacaa gtcattttca
    11221 aaaggtgacg tgattttaga gatcaacaaa gagttattga aagaaggatc aggcggaaca
    11281 agcccgattg agttacaaac aaaactcatt gataacttaa aagccaagtt tggcgataaa
    11341 gtttcagatg atttctattc aggtttacaa gcaagcttta atttcaatcc agtaatcgtt
    11401 gacggtacaa aagggctaac gatttccaag caaaatgacg atcaaagcca atggttacgg
    11461 acttggttct tagacactga aaaaacagcg caaaatacca aaattatcct acgcaatgat
    11521 ttttcttatg agtgggcaga ttggagaaac aaaggacaac atgatgagaa agtaggatca
    11581 atgtttacac aaattgattg ggctaatgat ttaagatatg aagttatagg gatagtaacc
    11641 agcaaacaag aaaaaaatat agaaaatatt ggtggagtat ttgtagttat gcaatacaac
    11701 gaaaaaattg gaaagtggca agttagcgga acgattggtg gtgtaatgta atatggacgt
    11761 aattgaccaa ataaaagaaa ccggatcaga cattttaagt tctgccggtg atgccatatc
    11821 aggaatattt gaaggcgtaa aagagagtgt agatagtgtt ttgcacccga tcgatagttt
    11881 attaggcagt tggggaagcg accttttaga agcaagcatg aaaattgcga ataagacaac
    11941 ttttgatatt ccaaatataa aattaattag caccattacc aacgtgtttg tctttgccac
    12001 tacgaccttt gcaatttgta ttgtgttgta taaggtcatt gaagcgcaaa tacaagcttc
    12061 taatgggagt ggtgacgcat tgaccgctaa tattgttcaa aagctgtttt actcgtctat
    12121 tgccttagca acgttgccct gggcaatgaa cttttttatc aaaaagattg ttgcaccaat
    12181 cggggaatat gtgattcaac aagtcgctaa tgatttgaat gtggaaacga tcggcgaacg
    12241 attgcgtaat ttcttagtat caaatttctt taatggtggc gttagcgccg ttgttctctt
    12301 tgttttcgtg atattctttg ccttttccat tgccaagtat tttgtagcga tctgtgtctt
    12361 ttatgccgat ttcttggtac tgactatgtt aacaccatta gttgccttat cgcttttaac
    12421 agacgaacaa aattactttc aaatatggat caaagaactg ttatccgaag cactcacaat
    12481 gcttattaag cttattttgt acttactcat gattacactc atgattgctg aaaaatacac
    12541 gttaccaaac tttatgttaa tggttggttg tggcttgttg attatcaaaa caccgtcagc
    12601 cctacaaaat atgtggtatt caaccaaagt gtcaaaaggt ggcggacttg gaaacttagc
    12661 aatgatggct atgtttagaa aataagagag actaactata tagagtcaag taaaaattag
    12721 ccaaatcaaa aaatatttta taacagataa ttccgaaaaa agggtacaac aaataagctt
    12781 cttaccatta gtttttttga atgttcaata gctaatcaga aacaattata taaggctcgt
    12841 ttttagtcaa aatagcatga atcacgtaac aaagcttacg agaaaccgca cctaaggcag
    12901 ttagatgatg ttttccttcg gaaacttttt tctggtaaaa cgcactaaaa acaggatcac
    12961 attgagaagc tactaaagcc gccgaaaaca aggcttttcg caaatatgga gaccctcgtt
    13021 tactcataac attatgcgtt gcctcatatt gccctgattg tgtcacggaa gcgtctatcc
    13081 cagcgtaagc aacgagtttt ttcgggttag aaaatttttg aatatctccg atctcaccaa
    13141 gaatagtcgc accgtttata ggaccaattc caggaattgt gagaataaca gaatttaaag
    13201 tgtccattat gtgcttgatt tctctttccg tttcctttat ttggctttca atgaatttta
    13261 attgttcaat cattgaacgt agttggaagg tgaacgcttc ttgagcaaat tttactccaa
    13321 aggagttaga agctgcttgc ttcaattggt ccgctttttc tgccttgatt cggttcctgc
    13381 ttaactcagc taagtattgg gccaaagttt ctgaggaaat gttttctaag tcgatcgggg
    13441 cactaaacgc cagcaataac tctttagaag cttttccgaa aacgccctgc ttggtaaaaa
    13501 tcgtcgcgta ttctggaaag acttgatcca atacggctat aatttttctt ttgaagtcgc
    13561 tcgctgtacc tactaaataa gttcggtaac gagaaagttg tttcaaagaa aaaacatttt
    13621 catcggataa gaccgtttcg acaaatgagc catagcgcat taagtcagca atcaaaacag
    13681 aatcaataat atcgtttttt cgtttccgta tttctgtacc tttacgccat ccgtctgttt
    13741 gaaggggatt cacaacgtga atcaaataat ctgattcgtg aaggtatgaa aagatggaca
    13801 gccaatagtg ccccgtggct tccatcccta taacaaagtc actgggtgct ccggaatagt
    13861 cgaccattcg ctcaattaat gactctgctc cttcagtggt gttaggaaat gaaaaacctt
    13921 ttagtaatac ctttccttcc tcgttcatga tagaagcaac gtgagtgcgt ttaccgatat
    13981 caatgcctaa aaagtacatg tatatctgac ctttcaaaaa aagaattttg gattgaaatc
    14041 cactcaactg aaaagcgtca ctaccttgta cgagatacgg agtaaagtaa ggactttcaa
    14101 catctaactc atacgcaatc cacttatcag agagaggagc cagtctctcg agtgcgggtt
    14161 caatgaccca aggggggaac ggcttagcct ctcaatccaa taaatatatt atctcaaaag
    14221 aaatgagtta ataccaaatt aaaataacga tggttcatag ggttatccaa tcaaaaccgg
    14281 aaggttaaaa ccctaactct aatatacaag ggggataacg attgtcttat tattttgaaa
    14341 tacgaattat tcttcccgaa gaagaaaaac aatttttgaa tcgaaaatta agtaaaagcg
    14401 aattatccga agtcacacac tatttacaac aaaagacaag tcgaggaatt ccagttaaat
    14461 ttcgtgtagg tatttttaga gtagaagatc aaacaaaaat tatgtctgtt acgctgaata
    14521 caaaaaatac caaagaaacg gacgtaatta acttgttatt aaatcgagta acagatcaac
    14581 acgttttagt ttacttgaat gaaccaacag aaccaacgct taatacgcaa gaattaaatc
    14641 gtcaggagtt aaaaacgagt aatgaacgcc aagaaatacc gcagacagaa attccaactg
    14701 aaacagtaaa tgaacctagt gttattaagg aaatatcgaa aaagaaccaa gcaaaacaaa
    14761 cgaatagtag aaaagaatca ctatcagaat ccataaccaa gaaaaatgtt cccaaaattc
    14821 atttgttcat atctattttg actcttttta ttgtattatt gataggaata agtgttattc
    14881 aacaagtaca acttcaatca gtcaaaaaag agagcgaatt attgaaagaa caaattgaac
    14941 gtgtcaaaga aacggatatt tctcaatcga aaatagatac ttttggaaga tactttttga
    15001 cttactattt ttcacaggaa aaaaatcaag aaaattatca gtcaagttta agaacatatg
    15061 tatccgaaaa ggtagatata gctgattgga aagcgttaga gaaaatgctt aagagtgtca
    15121 attactatgg tagtgaacaa acaaaaaaag ggtatagcgt tgaatacctt ctaaatgttt
    15181 cagtagacaa tcgtagtaaa atgcaaaaaa tcacttttga ggttgaacca actaaaaacg
    15241 gctttcttgt gacaactcaa ccaaaactta cagacttctc ttttaactga aatacgctaa
    15301 aaagagagtg cttaaacaat gggaaaaatt aatttaaatc aaatttacac agcaaaagaa
    15361 atgagtgaac ggataggtaa gaatagaaat tacctatccc aagcttaccg taacaacaaa
    15421 catgaaatac ttaaaaattt taattatcga aaaattggtg gaacaattat tttctctgat
    15481 aatcccaata atgatttatc gcaattgatt acagcaaaag aagcaagtca gttgttagga
    15541 aagaatgatg aatactttgc ccacatttat aaacggtttc ctcatagact agagggaatc
    15601 gatcacattt atacaggtaa aacattattc ttaacgaaag aatcgctaga agcttttaaa
    15661 aaaaagatga atggaaatgt cagataaagc atatttatga tatactattt atgtacacaa
    15721 atactaattt ttaaggagat tataaaatga aaaaattagc cctcttaaca ctattcagca
    15781 ctgcattatt agtatcagca ccgcttgtca gttttgcaga cgaaaccgca agtagcagtg
    15841 atgttactat cttagccgat gataatccag tcgttccagt agaaccgaca gacccgacta
    15901 ctccagttga tccagttgat ccagttgatc cagtcgatcc agtcgatcca gttgatccag
    15961 ttgatccagt tgatccagtc gatccagttg atccagtcga tccagtcga
//
LOCUS       DAXLPC010000063        15937 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.063, whole genome shotgun sequence.
ACCESSION   DAXLPC010000063 DAXLPC010000000
VERSION     DAXLPC010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.063"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(174..476)
                     /locus_tag="ACF3UE_001923"
     CDS             complement(174..476)
                     /locus_tag="ACF3UE_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFD3635308.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(696..1062)
                     /gene="ssrA"
                     /locus_tag="ACF3UE_001924"
     tmRNA           complement(696..1062)
                     /gene="ssrA"
                     /locus_tag="ACF3UE_001924"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1233..2006)
                     /locus_tag="ACF3UE_001925"
     CDS             complement(1233..2006)
                     /locus_tag="ACF3UE_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3635309.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2150..2500
                     /locus_tag="ACF3UE_001926"
     CDS             2150..2500
                     /locus_tag="ACF3UE_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFD3635310.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2481..3197
                     /locus_tag="ACF3UE_001927"
     CDS             2481..3197
                     /locus_tag="ACF3UE_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFD3635311.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3197..4645
                     /locus_tag="ACF3UE_001928"
     CDS             3197..4645
                     /locus_tag="ACF3UE_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3635312.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4715..5224)
                     /locus_tag="ACF3UE_001929"
     CDS             complement(4715..5224)
                     /locus_tag="ACF3UE_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635313.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5214..5938)
                     /locus_tag="ACF3UE_001930"
                     /pseudo
     CDS             complement(5214..5938)
                     /locus_tag="ACF3UE_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6161..8281)
                     /locus_tag="ACF3UE_001931"
     CDS             complement(6161..8281)
                     /locus_tag="ACF3UE_001931"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFD3635314.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            8511..9689
                     /locus_tag="ACF3UE_001932"
     CDS             8511..9689
                     /locus_tag="ACF3UE_001932"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFD3635315.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9705..10463
                     /gene="aroD"
                     /locus_tag="ACF3UE_001933"
     CDS             9705..10463
                     /gene="aroD"
                     /locus_tag="ACF3UE_001933"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFD3635316.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFFSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            10486..10971
                     /gene="ybaK"
                     /locus_tag="ACF3UE_001934"
     CDS             10486..10971
                     /gene="ybaK"
                     /locus_tag="ACF3UE_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFD3635317.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(11042..12295)
                     /locus_tag="ACF3UE_001935"
     CDS             complement(11042..12295)
                     /locus_tag="ACF3UE_001935"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD3635318.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            12412..13761
                     /gene="gdhA"
                     /locus_tag="ACF3UE_001936"
     CDS             12412..13761
                     /gene="gdhA"
                     /locus_tag="ACF3UE_001936"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFD3635319.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            13873..15219
                     /locus_tag="ACF3UE_001937"
     CDS             13873..15219
                     /locus_tag="ACF3UE_001937"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFD3635320.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(15527..15913)
                     /locus_tag="ACF3UE_001938"
     CDS             complement(15527..15913)
                     /locus_tag="ACF3UE_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFD3635321.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         5216 a         2844 c         3191 g         4686 t
ORIGIN      
        1 acttataatt ggagtggtag ttaattagtg acttattttt gattttatag cactgatact
       61 ataaaatata gatatcatca tattacacaa tcttaatact aacttaaaaa atatcccttt
      121 tataagtatg gtgataaaat ccgttccggg ctaccttttt taggtagcct actttaatct
      181 ttataccttt ctggatcaac gaaagtatac ttcaaatagt cataacgccg atgatcgctc
      241 cgtgcgtctg gcacatcagt cacgatatca aacaaaaaat acacatcttt cttcattctg
      301 gtttttgttg ccggaatttt aaagtagttc ttattagagt aatagagatt gattaataag
      361 ctatcttcga ttgctaaaaa gaaaacttct gaatcccaca ccttataaaa atctttgaca
      421 aatctattcg aaggatcaaa tttaaaccat aattgtgttt ttccttccat caacataatg
      481 ttcacctcaa aaagagtata cgaactaatg ttctttttgt aaagtaggaa tatcattgat
      541 aatatggatg gaacatatat attaaaaagt gttctttttg aatgctattt tgaatgccat
      601 tttcattcat ttaacgaaaa tctgcgaaaa taaaaaatgc tcaaaccctt ataaaataag
      661 gatttaagca tctagcgaaa tctgctgaaa tctcacaatg gagacggcgg gagtcgaacc
      721 cgcgtccaaa cacatcgcca cttaaaaatc tacgttcata gtcaactcat ttaaggattc
      781 actttacagc ttgccgagtg acaggcattc tgtatcgcta gtctgatgtt ctctttttca
      841 acttacagac ggaaagttga aacgtatccc actaaagtta ggacccttac tcgagcacat
      901 gggcgatgcc gagaggatct acgctaactg tttttaggca gctaaagcgt aagagttgtt
      961 ttcgttttta gcagttatat ttaactgtaa cgtttttacg tagacgtaac ctacgaaacg
     1021 caattcaagc tcgactgtgc ctgtcgaatc cgtaacgtcc ccgttagcta acaagggtta
     1081 cgtgtatttt tcatacaaaa ttagtatagc atatattggg ataaattcaa taaaaaagcg
     1141 aatcatatcc cattatttat ataataactg cccctttctt aagaaaaaat aagcgatttt
     1201 cttaagaaaa gaggtagctt caaaaaaaga tcttaaatca gatcaaaata cttcaatgcg
     1261 tggacaattc cgccttctgt atttttcttt gtgataaagg tagaaagttc ttttaatccg
     1321 tcataggcgt tgcccatagc gattttgttg tcgcaagctt ccaacaaggc aaaatcattc
     1381 ggaccatcgc caaatccaaa agtaggaact ttttccagct gaagttcttt ttgcagacgt
     1441 ttgacacctg ccccttttga gattcctttc ttcactgtat cgatcgagta aggaccattc
     1501 cgataaaaag ttagctcagg aaaatgttcg tgatagtatt cgtcacctga ttgagataag
     1561 atcagcaaca tatttactgt gttttcttta aagcctaaag gatcaatttc cggaacatct
     1621 gaatgaatga agtcgtaagc attgatcatt gtttggctat gaccggtaca ccagattttc
     1681 tgatcgttat agtaagaaag ttcatgaccg ttcaactgta catgatcata cattttttga
     1741 cattcttctg aagaaaatgt ttgagaatag atttcttcgc cgtctactcg aatgaaagaa
     1801 ccattcatgg tgaccgcaga agtaatgccc gcatcttcca tgatagagtg gatttctgct
     1861 tctgtacgtc ctgtagcgat gacggggaga acattgtttt cttttaatgc gttcatagct
     1921 tttgccactt cgggtgtgat ttttgatttc gcatctagta atgttccatc aagatcaaag
     1981 aaagtgattg cacgataatt tgacacaaat aaaactcctt ttttattgga ataagtttat
     2041 cttaacaaag aatgaacaaa agacaaacct ttcgtgaaga attcctgaac atattggttc
     2101 agtcaacaat ttagagtata ctataagaag agaatttagg agggaaagaa tgattttttt
     2161 cagtattggt atcttattct taataattgg cagtcttttt cggattctgc cctcaaaagg
     2221 aaatctgcct ttttatgggt atcattcgcc tcttgccgca aaaacagacg ctcattggcg
     2281 gctggctcaa aagacaagcg gaaactggtt ttttcttatg ggcttactga tggcattgat
     2341 cggctattat ttaaagacat ctgggcatac gaattatttt ctgattgaaa tgcttctgct
     2401 agtatttcca attatgccta tttttattat gacagaaaag aaattacaga aatatgacct
     2461 ggaaactgga gggaacgata atgaatattt taatgattga agataatcaa tctgtttctg
     2521 aaatgatgca gatgtttttc ttaaatgaag gttgggaagc aactttcaag tatgatggaa
     2581 aagaagggct cgatgccttt ttagaaaacc cacaacattg ggatatgatt acactagacc
     2641 tgaatttgcc cacactggac ggtatgctag taggaagaga gatccgcaaa gtttcaagta
     2701 ctgtgccgat tatcatgctg acagctagag attctgaaag cgatcaggtg atcggcttag
     2761 agatgggggc agatgattat gtcacaaaac ctttcagtcc tctgacgctt attgctcgaa
     2821 tgaaagcttt gcatcgccgt agtgagttgg cagaagcaag agaagaagca gtagtttcag
     2881 atgatcattt tgatatcgag actagtcatt tcaagatgaa tacgaaaaca cgagaagcgt
     2941 atctggacaa ccggccaatt gaaggactga cgcctaaaga gttcgatcta ttgtttactt
     3001 tagcaaaaaa accacgtcaa gtattctctc gggagcagtt gcttgaatta gtctgggatt
     3061 atcagtactt tggtgatgaa cggacagtgg acgcccatat caagaaatta cgacaaaaaa
     3121 tcgaaaaggt cggaccacaa gtcatccaaa ctgtttgggg agtcggctac aaattcgatg
     3181 attctggtgt tgcctaatgc gttatttgta tcagcaactc ttagctttct gcggaatggt
     3241 cgcgttgatc ttattgatcg ttggagtttc ttttacacaa ctgacaaaac aaacgattga
     3301 agaaaacaat taccagcaac tgtttggata tgctgaatca gttgaaaaga caacgcaaac
     3361 ctatgccgat acgctcccgc agtttagtca agatcaggcg tttcaaaatg cattgctgct
     3421 gacagagcaa gtactgacag aacaaaatgt gaactttata tttatcgata aaaacgaacg
     3481 tgtcatttat ccgactaata cagctttact gaattttacc ttaacagctg atcaatggaa
     3541 aaatctgagg aatggacgtc aagaaaaatt cacatcgaat aaaaatattt taggacaagc
     3601 acaggcgacc tcttacgcac ttgtgccatt taatttgaat catgaattct atggagcact
     3661 tgtagttagt caacctgcgc gaaatatcga taacagcgtt cgtccaatta cactgaacct
     3721 gttcaaagga tttatttttt ccagtatcgt tgcagttatt gccagctatg cttttgcagc
     3781 attccaagtt aagcgtatca atcggttaag gaatgcgacg aaagaagtga cgaatggtaa
     3841 ttttgatgta cagctccccg tacatgacaa agatgaattt gatgagttag cagatgattt
     3901 caataaaatg acgaattcat tgaaagaatc tcaagcagaa attgaagaac aagaaaatcg
     3961 tcgaagacaa tttatggcag atgcttctca cgagatgaga acacctctta cgacaatcaa
     4021 cggacttctg gaagggttag aatacaatgc aatccctgaa aatcagcgag aaaacgcgat
     4081 taaattgatg aaaaatgaaa cagagcgtct gatccgtttg gtgaatgaaa acttggatta
     4141 tgaaaaaatc cgtacgaatc aaatcagtat ggtcattaaa aaattcaatg gaacagaaac
     4201 attgaaaaat attgttgcac agttagaagc taaagcagaa gcagcaggag atacattgac
     4261 attgaaagcc gttgatgata ttgatgttta cgctgattat gaccgatttg tccaaatcat
     4321 ggtcaatatt attcaaaacg cgatacagtt tactgaaaac ggccaaatca cgattacttt
     4381 agaaaaaggc tatcttgaaa cgatcatcac gattgaagat acgggaattg gaatgtctga
     4441 acaacaaatg aaaagtatct gggatcgtta ttataaagta gatccttcaa gaaaaaatac
     4501 aaaatatggt gaatcaggat taggtttacc aatcgtgcag caacttgtac gcttgcataa
     4561 aggaaaatta gaagtagaaa gcgaactagg aaaaggaaca aaattcgctg ttcgtttgcc
     4621 tgacgtagaa atcaaaaaag agtaaaaaac aagcggtata aaagatcatg aatcgatctt
     4681 ctataccgct tgtttttact ataaaatgat tgatttagcc cgcgggctct aaacgatcaa
     4741 tataaggact ttgagcaata gtagcatcat gagtaaagag taagatacct tgattttctt
     4801 catgagctaa ataagaaagc aagtggagta gctcttggat ctccaataca ctaagttcat
     4861 caaatgtatc ttcaataaca atattgtttc gcttggaaag caaggcatga agtaattgca
     4921 gctttacttt ttcaaaagac gtcaactcag ctgccgcaca attaagcaag gaaggagaga
     4981 tatcaagttt ttcttgatag gccaaacgat cttgtttgat ttctttttcc ggtacatcca
     5041 acaggacatg gtctttaaga ttcagataag gaaacatcgg ccaatttttt tggatgatcg
     5101 caaaattatc cagttttgca acaagaacct cttttttcaa gtgctccaat attttatgct
     5161 gtttttcgag aggacacaaa ataacggtca agtgttcagc atgaatcaaa tattcaggtt
     5221 tcattacgtc caggcctcct actttgcaaa tgatggataa aaaagtgaaa gggaatagac
     5281 taagaatgag acagcatcca ctgagcccaa taagagtttg ggcaaatccc ttaagtatat
     5341 ctgtgaaaaa aagatcattt tggaaatcga tggtaaaaaa agtctgttga tccatcggaa
     5401 ttgtaagtcc gcttaccgaa gtcaagatat cacggatatc tggcagttca gtagtcttta
     5461 agacaagaaa attgatcctt tgaagaagcg cttcataaac tgactggaag cttacgatcc
     5521 acaataaaac caagatacaa caaagaaaga gaggaaagaa cagctgccag aaaataaaaa
     5581 ggaataattt ggttttagaa agaccagtca ggtgccaatt gatcaattcc tgcttgtttt
     5641 gcctgactga atagtaaaag aaaaagataa aaaggaaggc aaatagaaaa aataaactga
     5701 atatgccttt tatataaaat cggctagcta attctaaagc cggaagaagc tctgtagatg
     5761 cagaagcgcc aataaatgaa agccgatctt ggacttgatt ggctaaagcc gattgcaaat
     5821 ggtaaagagt caggcatgct atcaataaaa aagcagaaaa gcttgaaaat aaacaataga
     5881 gtattgtctg ctttttgtaa taaattaatc gagcagtagc atagcggatt attttcatac
     5941 ttttcacctc tataaaaagt atagaaaatg aatatgaata aagtatgaaa ttcctttagt
     6001 gaaatcacga attaaaacca gaaaatattt tgtaaaaagc aagaggttgt gaagaagctg
     6061 ccctattcta ttaccgtaga tgcaagcttt tgaacactgt ttattcgaaa agaggagcag
     6121 cgacaataat tttgtcgctg ctccttttaa atttatttta tcattcggaa gaacttgtgg
     6181 tcgttccgtg aagttcttgg tacgtttgcg ttttataaag atcaacagtt gattgtccgt
     6241 tgtgttcact aaagacacta gttgacttgt caccaagaga tttttcagct tcttttaatt
     6301 tctctaagcc attcttgtag tcataatcac tggtatcaat tgggtctaat ccactattcg
     6361 tatagaaccg aagaagatca ccattattga tttggtcaga aacagctaac tgtttatcaa
     6421 ctttttcttt cagtgaatca atttcattct gtacttcctc agtaggttca gtaatagctt
     6481 caccagtttc gttactatag atcgtaccac cgtagtaagt atattttggt gtaacaaaat
     6541 caccatcacg gaaagaaaca agctgttcat gatctttcga gaatagatct tgtcctaact
     6601 gaatataatt ttttgtatct acacctagta agtgaagtaa tgtaggcaag gcatcaactt
     6661 gtccgccgta agtgtgattg attccgccct gtgtttgtcc agggatatgg atcatataag
     6721 ggacacgctg catttgtgca ttgtcgtagt ttgtccaagt agaacttgtt tttccaacta
     6781 attcagctag atttttattt cttgaattcg agacaccgta atggtcaccg taaaggacga
     6841 tgactgaatt atcatacaag ccgctttctt tcaaataatt gaagaattct tgtacggcgg
     6901 tatctaaata attggctgtc gcaaagtaac cgttgatcgt ttcatcattt gtattggcta
     6961 acgggaatcc tgcttcgtca ttggtgaatt ttgaataagg ataatggtta gatacagcaa
     7021 tgaattttga ataaaatggt tgttgcagac gttccaagta ttgtacggat tgttggaaaa
     7081 atggtttatc atgcaacccg tattggaacg aattgtcatc attaacatca taataagaag
     7141 aatcaaagaa ataatcatat cctaaattct tgtatgtctc gtttcgattc cagaatgtac
     7201 cagcgttccc atggaatacc gcactaatgt aaccttgtgt ttgacttaaa atatcaggtg
     7261 cagcttggaa agtatttttt ccgcctaatt gtgtgaacaa ggagccttga ttcaagccaa
     7321 acaatgaatt ttccatcagc gtttccgcat cgcttgtttt tcctgctttt acttgatgga
     7381 aaaagttgtc aaaactgaac gtgctgttgc tgtggtaaag actattgatg aaaggtgtaa
     7441 cttcatgctg gagaccattc tcatctgtca atttataatc gatcaggaat tgctggaagc
     7501 tttctaaatg gatataaatc acattttttc ctctagcgag cccgaacaaa tcgtcatttg
     7561 gtgctgcata atgttctttt acataatttt ctacttcttt catatcattg ggacttgctt
     7621 ctgcccgcac ttggtttgtc tggtaagttt gaacaccgtc ataaaccatg aaagcattca
     7681 agccaagata tttgaccaaa taatcacgag agaatgttcg agtcagcaat tctggacgat
     7741 cagcttccgc cataaaaaga tttcctgaga aaatcataac tgctaatgta gagatcgcaa
     7801 aagccattct tgctcggatc gggcgagggt ccaacttgat tttttttgca atcagcagaa
     7861 cagtcaagat aataaaatcg atccaataga tcacatcata tgggcgaaac agtcgaatgg
     7921 cactttctcc cagaccactc gctactttcc cagcacctaa aatcgtgttg atcgtaatga
     7981 agtccgtgaa ttctcgataa taagtgacat tcgaaaaaac aagcaatgtc aaaagaaaat
     8041 aaatgaccat catcgtgata taagcaactc tagggcgtct gatataaaga gcaattccaa
     8101 gtaataacaa tgtagttgca atagggttga taaacaagat aaagtattga atgccacttt
     8161 cgattccgag atggaaatca actaaatagg caaaaatcgt tttcaaccaa agtaaaacga
     8221 ctagtaaaga aaaaaatccg agcctcttat tcaaaaaggc aggtgttttt atacatttca
     8281 agataatctt cctttctgca cttcttaatc acagaagtgt cctgaaacca tgttacacag
     8341 ctcacttatt ctcatttatt ttactagtat gacaatatag tgtcaattga aaccagaagt
     8401 ttatgctgtt tcattaaggt tttctttaag cttcatgaaa aaatgagcag taagacaagt
     8461 cctatgtttt ttgttatact tgggaagaga aagctaaagc aggtgaagga atgaaagtaa
     8521 aagtaaaaaa aagagcaagc aatcgattga aaaaaggata tccactgatc caaaaagaag
     8581 accttgctca tccccaaaaa gaaaccacgc aatgggtgga attagttgat tcgcaaaacc
     8641 aatttatcgc aaaaggatat ctaggaaagc agaataaggg aatcggttgg gtattgagcc
     8701 agcagaacat cccatttgat caatcttttt ttgaagaatt ttttgtgaag tcaaaagaaa
     8761 aaagaacttt ctttttttca gatgattcta ctaccgcttt tcgtatattc aatggagaag
     8821 gagacgggat cggcggtctg attgttgatt attatgcagg ttatgctgtt ttttcttggt
     8881 ataacgaaac gttatatgca catcgtgaat tattgattca agcttttcgt gaaatctacc
     8941 cggaaatcat aggaggctat gagaaaattc gatttgaatc agtaaatctg cctgagagcc
     9001 agttcattta cggaaaagag gcaccggaac ccttgatcgt aaaagaaaac ggagtaaaat
     9061 ttgccgttta tttaaatgaa ggattaatga ctgggatctt tttagaccaa aaagaagtac
     9121 ggggatcatt agcagaaggt ttcgcttctg ggaaaacagt tttgaacatg tttagttata
     9181 ccggcgcctt ttctgttgct gccgcaatgg gaggggcaat cgaaacaaca agtgtcgatc
     9241 tagcaaaacg cagtttaaaa aaaacacagg aacagtttga agtgaatggt ttggatgtcg
     9301 atcagcaaaa aatcattgtt atggacgtat tcgagtattt caaatacgcc aaaagaaaac
     9361 aatttttata tgacatgatt gtattggatc caccaagttt tgccagaaat aagaaaaaag
     9421 tctttcgcgt agcaaaagat tatggggaac tggtcaagga tagtctggat attttagcag
     9481 aagacgggat acttattgcg tctacaaatg ctgcgaatgt ctcgatagaa caattccaaa
     9541 caatgattga agaggaattc catgccaaaa atgtttcttt tgaacaactt gctttatatc
     9601 gtctgccaaa agatttccag acgacggata cctttttaga aggcaattat ctgaaagtgt
     9661 ttgtttatca aattaaaaat aaccattaga aggagcgatg cagaatggtt cgggtaaagg
     9721 gattgaatat aggaagcggt agaccaaaga tttgtgcgcc tcttatcggg gccgtccgag
     9781 aggaagtatt acgtgaagca gttcttgcac gtgaagcagg ggccgattta gtcgaatggc
     9841 gagtcgatca ttatcgtgaa gttttttctt ttgatgaagt agcagaaaca ttggttctta
     9901 tccatgagat gcttgatgga ctgccgttat tatttacgtt tcgtacctta gctgaaggcg
     9961 gagaacaaga catatcgatc cgtcagtatc gcgaccttta tgaacatgtg atacacacag
    10021 gattagtaga tatggtcgat atcgagttgt tcaaagtaga aagtctagga aaaagactga
    10081 tagaggaaat caagtcttta aacattcctt taattatcag tagtcatgat tttaaagaaa
    10141 caccagcaga ccctgtcttg ctttaccgat tgaatgttat ggaacatttt ggagccgata
    10201 tcggaaaact ggcagtaact cccaataatg aacgagatgt tttgcggttg atggagttga
    10261 ctagacgggc aaatgctttt ttctccatgc ctattattac gatgtccatg ggaaatcttg
    10321 gtaaaatttc tcgtctggtt ggcggaacga cgggttccgt tatgacattt ggttccttaa
    10381 gcagcgattc tacttctgct ccaggacaat taccggtcaa agcattgaag caaattattc
    10441 aattattaaa tgaaccgttg tagaacaagt ttgaggtgat attttttggc aaagaaaaaa
    10501 atagtaaaaa cgaatgcaat ccgtatggtc gaacaaaaaa agattcccta tacagagcac
    10561 gaatatgagt gggacgaaag ccacctaagt gcgtcatcgg tcgctgaaca gcttccagaa
    10621 agccaatctc gtatatttaa aacactggtt gctgtgggca atgtgacggg gcctcttgtt
    10681 gctgtgatac cgggagaagc cgaattgaat ctaaaaaaat tagcaaaagt ttcagggaat
    10741 aaaaaagtag aaatgctcca tttaaaagat ttggaagcaa cgaccggata catacgtggt
    10801 ggctgctcgc ctataggtat gaaaaaacta tttcctactt atttagatca aattgcagaa
    10861 agctatgaac aaatcattgt ctcggctggc agaagagggc tacagatgga gttagcacct
    10921 caagatatct gtgcattaac gagcggacaa tttgcagata taaaacaata aatcatacgt
    10981 ataaaagaaa gaaggaggcc gggatgttgt ttgtccagtc tccttctttc ttttttatac
    11041 attatgctct ttgcccggca ttcattcctg ctacatgccc tgtagcgaaa gccgctgtga
    11101 tattaaagcc gccagtataa ccattgacat ccagtaattc tcccgcaaaa tacagaccat
    11161 caatgatttt actctccaat gttttaggat aaatttcctt tagagaaacc cctccgccag
    11221 ttacaaatga tttctcaata ggaaaagttt tgttgattga tagcttaaac tctttgcata
    11281 gttgaacaaa atcttgaatt tgtttttgag aggcttgttg tcctgtcaga tgatccattt
    11341 caagccgctc aagaaagaaa actaacaatc gctcaggcaa tataccatgc caagcattga
    11401 ccaagttctt tttggttgct ttactttttt ctgtcaatat atgaataagc tcttgtttgg
    11461 tttgtgtagg gaaacaatcc agagaaagtg tcactggttc tcccgttttc tctaattctt
    11521 tattgacaaa acttgaacaa cgcagtgcag ccggaccaga aataccgaaa tgggtgaaaa
    11581 gtaaatccat cgtatgttca gtcaatacac gacctttttt atttaaaacg cgtaaagtga
    11641 tgtcttgtaa agaaagccct tgaagtgttt tctcctgaat atacggttca tccgatatca
    11701 agggggactc tgtcgcataa agaggcgtca ccgtgtgacc cactcgcttc acgatcttgt
    11761 acccatctcc agtagaacca gtagatggat aagtccgtcc accagttgtt aagataatgg
    11821 caggagcatg gaactcttcg aattccgtgc gtataccgta aattttatgt tctttgtgga
    11881 tcaatttctc tactcgagta gagaatagaa gcgtcacatc tagttctttc agacgattga
    11941 gcaatgcttc gataatcgtt tttgatttat ttgttacagg aaacatccgt ccatgatcct
    12001 cttcttttaa atgtacgcct tgtgattcaa agaagttcat gatatcgaaa ttattccatt
    12061 gcgcaaacgt actatataaa aactttccat ttccaggaat atgtgcaatc aaatcatcaa
    12121 caggacgatt gttcgtaaca ttgcaccgac caccacctgt catcagtagt ttttttcctg
    12181 cttttttgtt tttttcgatc aagagtacgc gtgcgccttg ttcagctgca ctgatcgctg
    12241 ccatcatccc gcttgttcca gcgccgacta cgatcacatc atacagtttt tccattccct
    12301 cacctcaagg aaagtgtagc atatctgaag aaagaaaaca gaaaaaaatg ttttgagcca
    12361 aaagagaaaa tgagctaaaa tgagggaaga taagcaaagg agcgtggaac gatgacaaac
    12421 gcaacagaat atgttcaagc aattcaagaa aagctacatc aaaaggatca agggcaagaa
    12481 gaatttttac aagcaatcga tgaattcatg cccacggtta tgtctttttt ggacactcat
    12541 cccgaatata tcgaaaagaa tatcttagaa cttttaacgg aaccagaaag agttattcaa
    12601 tttcgagtgc cttggcaaga tgatgaagga aactggcgag taaatagagg gtaccgtatc
    12661 caatacaact cagctatcgg cccttataaa ggtggattgc gcttccatcc tagtgtcaat
    12721 ctaagtatct tgaaattttt ggcttttgaa cagattttca agaatagttt aaccggtctg
    12781 ccaatcggtg gaggaaaagg cggaagtgac ttcgatccta aaggaaaatc tgataatgag
    12841 atcatgcgtt tttgtcaaag tttcatgctg gaattgtcaa aacatatcgg cccatcgatt
    12901 gatgttcctg cgggagatat cggtgtagga gctagagaaa tcggctattt gttcggcgaa
    12961 tataaacgat tgaaaaaata tgatactggt gtgttgacag gtaaaccttt ggatttttgg
    13021 ggaagtaaga tacgtacgga agctactggt tatggattag tgtattatgt caaacatcta
    13081 ttgaacgaag aaaaagattc atttaatcaa aaaacagttt ttgtttccgg aagcgggaat
    13141 gtagccattt atgcaatcga aaaagtgcaa gagctaggcg ggaaagttgt tacatgttca
    13201 gattctagcg ggtacatcta tgatccagaa ggaatagatg tgaaactatt gaaagaagtc
    13261 aaagaaatca atagacaacg tttgacggaa tacgcaaacc aacgtccttc tgctatttat
    13321 catgctggag aatctgtttg gacattgaaa gaaaaagcgg atatcgcttt gccatgtgct
    13381 actcaaaatg aaatagacga aagcttggcc gaaatcttag tagaaaatgg gatcaaaatc
    13441 gtagcagaag gcgctaatat gccatgtaca gtaaaagctg tttctgttct tcatgaagca
    13501 ggcgtgtggt attgtccagg aaaagctgct aatgctggag gagtagcagt atctgcttta
    13561 gaaatgagtc agaacgtcca gcgattgact tgggaaagag agcaagtgga tgagcagctg
    13621 gatcaaatca tggaaacgat ttaccatacg tgtcgccaaa cagcagccga gtacggcgac
    13681 gaaaaaaatc tgcttcttgg agcaaatgtt gctggatttg aaaaagttgc caaagcaatg
    13741 gcagcagaag gtttagtttg aaaaatgaaa ctttcttgga aatattgtca gcattttgtt
    13801 tatttgcttg aaaaataata aaaaaaaacg taaagtatta cctgtagagt aaacctataa
    13861 ggaggagaac aaatggcaca cattcatttt gactattcaa aagtagcacc gtttgtcaac
    13921 gaacaagagt tagggtacat gcaaagccaa gtaacagcag cccacaacga attacgggaa
    13981 ggtactggcg caggaagcga cttccgcggc tggatcgatt taccaacgaa ctatgacaaa
    14041 gaagaatttg cacgtatcaa agaagcagct aaaaaaatcc aatctgattc tgaagtatta
    14101 gttgttatcg gtatcggtgg ttcttattta ggcgctcgtg cagcgatcga cttcttgaat
    14161 cacacattct tcaatttatt agatagcaac acaagaaaag caccacaaat cttctttgcc
    14221 ggaaattcaa tcagctcaac atatattgct gacttgatcg aagtaatcgg tgatcgcgac
    14281 ttttcagtaa acgttatttc aaaatctgga acaactactg aaccagcgat tgcgttccgt
    14341 gtattcaaag agcttcttgt taagaaatat ggacaagaag aagcaaacaa acgtatctac
    14401 gctacaacag ataaagcaaa aggtgcagtt aaagtagaag cagatgcaga aggttgggaa
    14461 actttcgtga ttcctgatga catcggcgga cgtttctctg tattaactgc tgttggtttg
    14521 ttaccaatcg ctgttagtgg tgcagatatc gatgcattga tgcaaggtgc cgctgatgca
    14581 agcaaagcat actcaagcga caaactagaa gaaaacgaag cttaccaata cgcagcaatg
    14641 cgcaacattc tttaccgtaa aggcaaagta actgagttgt tgatcaacta tgaaccagga
    14701 atgcaatact tctcagaatg gtggaaacaa ttgtatggtg aatctgaagg aaaagaccaa
    14761 aaaggcatct atccttcaag cgcaaacttc tcaactgatt tgcactcttt aggacaattc
    14821 atccaagaag gacgtcgcaa tatttttgaa acagttgtga aggttgaaaa acctcgtaaa
    14881 tcaatcacaa ttcctgaaca agcagaagat ttagacggtc taggctactt gcaaggaaaa
    14941 gaagtggact tcgtaaatac aaaagcattt gaaggaacat tgcttgctca tacagacggt
    15001 gacgtgccta acttgctagt caaaattcca gaaatggatg cttatacatt gggttataca
    15061 atgtacttct ttgaaattgc tgtaggtatt tcaggttact tgaatggaat caacccattc
    15121 gaccaaccag gtgtagaagc ttacaagaaa aacatgttcg cacttctagg caaaccaggc
    15181 tttgaagatc ttgctaaaga attgaacgaa cgcctgtaag ataagggttt ttcgctagat
    15241 ttaaataatc agtgatagaa acatgttcgc tttaaaatga aaactggtac ccatttaggt
    15301 actcaaacat actgcatcgt ttattcagaa taaggggctg tgacaagacg tttgtcacag
    15361 tcccttgttt gtatagaaat cgattgattg ccttgctctt tagtttgttt taggacttta
    15421 agaacagtga ggctgacttc gaaggttaat tctgtttttt tgttttctag aatcagtaag
    15481 caaaaaagca ctcacttcga gtgctttttt gcgatatatt cttagcttaa gataggccta
    15541 atttttcttt tacagatgag ggtaccttat cgctggtaat tacttttttc tctatgatcc
    15601 gcttttcgct tgctttcaac tgcaagatcg ttccttcggg gtaagcagaa ccattggcag
    15661 agtcaccaga agtaatgaca tcgaaatcta actgtctttt ttcaccgttt tcagcataag
    15721 catctacgtt gtatttaaaa cctcttccaa ttacttcccc attatctgct ttgatatcag
    15781 tttctgcagg cattggagct ttgactaccg cataataatc tttacctaca taagtagact
    15841 gatagtagtc ccaacctttc catcctataa aagcaatcaa tatgataacg atcaacccta
    15901 aaattttttt catgaaagat ctcctttttt attttta
//
LOCUS       DAXLPC010000064        15026 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.064, whole genome shotgun sequence.
ACCESSION   DAXLPC010000064 DAXLPC010000000
VERSION     DAXLPC010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.064"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="ACF3UE_001939"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="ACF3UE_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFD3635322.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="ACF3UE_001940"
     CDS             complement(323..892)
                     /locus_tag="ACF3UE_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFD3635323.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="ACF3UE_001941"
     CDS             1078..1980
                     /locus_tag="ACF3UE_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFD3635324.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="ACF3UE_001942"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="ACF3UE_001942"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFD3635325.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="ACF3UE_001943"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="ACF3UE_001943"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFD3635326.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="ACF3UE_001944"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="ACF3UE_001944"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFD3635327.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="ACF3UE_001945"
     CDS             8548..8733
                     /locus_tag="ACF3UE_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFD3635328.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="ACF3UE_001946"
     CDS             complement(8795..9991)
                     /locus_tag="ACF3UE_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFD3635329.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10126..11586)
                     /locus_tag="ACF3UE_001947"
     CDS             complement(10126..11586)
                     /locus_tag="ACF3UE_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFD3635330.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILTKEKGLEQYLF"
     gene            11879..12688
                     /locus_tag="ACF3UE_001948"
     CDS             11879..12688
                     /locus_tag="ACF3UE_001948"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3635331.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(12874..15024)
                     /locus_tag="ACF3UE_001949"
     CDS             complement(12874..15024)
                     /locus_tag="ACF3UE_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFD3635332.1"
                     /translation="MKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFFI
                     IFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKAN
                     QAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKRL
                     SAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGVT
                     DQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLAK
                     GYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSMN
                     AEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEIT
                     ENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRSG
                     QVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFGL
                     GTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQY
                     ASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGFH
                     QVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEIA
                     ISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT         4390 a         3183 c         2660 g         4793 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaaatgat gaagttgata atgaataaaa tatcaacgat
    10201 ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa ttgtatagaa
    10261 aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa agatcgatgc
    10321 aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa aagaagccat
    10381 catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta caatggcgat
    10441 cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg aagtcaaacc
    10501 agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg tattcgatgt
    10561 accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt tatccatttt
    10621 tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga aaatacctgt
    10681 gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata aactgaatgc
    10741 gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag attgcatgcc
    10801 ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat tacctaacga
    10861 attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac caaggactgt
    10921 ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta aaatggctgt
    10981 cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg ctaacgcagg
    11041 gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga cagagctcga
    11101 aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc cgacatacgc
    11161 aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa tcgcccgaat
    11221 aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc aaataaacac
    11281 cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa aagtgaaaaa
    11341 tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca atcccattac
    11401 cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga agggcatacc
    11461 tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa agaatgtcgt
    11521 tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac cgaaaaactt
    11581 ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa taataaaaaa
    11641 taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt tcattcgctt
    11701 ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt ttagcttatg
    11761 tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat tgctcttgtt
    11821 aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag gacccttatt
    11881 gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag attcgatgat
    11941 tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc atgtcagtat
    12001 tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag aattaacaac
    12061 accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact gggatggtga
    12121 aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa aaaagcagct
    12181 aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca gttttgattt
    12241 ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc tttctcctaa
    12301 aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt ttgcaggagc
    12361 tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga catggggtgg
    12421 acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag gcgtgcaaga
    12481 gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg acgagcataa
    12541 tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg gtactgacca
    12601 actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg gtttagctgt
    12661 ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa aagaggttgt
    12721 gacaattttt gtcacaacct tttttgccga gtaaacggtg ttcaaaagcc agtttctcgg
    12781 tatgaagtca aatttaagca aaaatgtgag aagctatttt cacaaaattt ttcttcatac
    12841 tcgaaactaa gcggcttttt cacgacctct tttttatttt gccatgaaca tatcataata
    12901 cgcgtccatt atttctttag caatcgtcaa gtttatgtgg tcttgttcgt ctaataagtt
    12961 cggcaagaca acactgatgg caatttccgg attgtctgtt ggtccgtatg ccacgatatt
    13021 actattgact gtcgcaatat ctggatgacc ttccgcaacc gtttctgcag tccctgtttt
    13081 tgcggaaagg tccattttcg cactggctaa tggtttggct gttgtgtaag gatcggtacc
    13141 atggacaact tggtggaatc cttcacggag gatcgccata ttttctgcag aaatattgac
    13201 cgtattttct actgttgtgc caatttcttt cttcacttca cccaagtttc cattttcgtc
    13261 attgccatag atcgctttga ctaggtgcgg ctgtactcgt ttcccgccat tagcgactgt
    13321 tgaagcatat tgagctaatt ggattggtgt atatgtgtca aactgtccaa atgccaaatc
    13381 ggtaaagtta cctggagcat accattcttt gccattatcc gcattgaact tcttcatata
    13441 atcaacagaa cgtgagatcc caggagattc attcggcaaa tcgatcccag tcgttgtacc
    13501 aagaccaaac tctttgaaag agtctctcaa ttgctgataa gctttagctt cttcatctaa
    13561 actaggtagt cccattccag gtgtatagtc tagtcctaac atctttaacg ccactttgat
    13621 catatacgta ttagaagaca attccgatgc tttgactgca tcaagagcaa cttgtccgct
    13681 tcgattaaag acagagcttt tttctgaagc accttgcaga cgaatcggct catcaatcaa
    13741 aacttgattt ccgctgatcg cgttacttgc ccagcctgct gtcaaagtac cagccttgac
    13801 tacagaccct ggatcaaagg cgctagtaat cgtgcctaaa gcattctcgg tgatttcttt
    13861 ggaaccttgt tcatgactga aaccagtcat tgctagcact tctcctgtct gaggattcat
    13921 agccactgca taagcaccag gcgaatactg tgctttgccg ttgttgatca atgtttgata
    13981 attccttttc aaaatttctt ctacttttga ttggaattct gcattcatag ataacattaa
    14041 attagaacct ttttccccag agaagatttc tttttgattc gaaacatttc cttcattatc
    14101 aagggaaact tcatattggg ttttggttcc ttgcaggaca tcttcatatt gtttttccaa
    14161 ataactttgt cctacacggt cattccgaga ataacctttt gctaggtatt tctctgcttc
    14221 atctgctgga agtccttgct tttcagtcgt cacactgcca agaatacttt tcagtgaact
    14281 tgctgcatta tattctcgtg tccagtctgt gccagtcgaa actcctggaa gttcagaagc
    14341 gcgttctgcc acaacagcta actcttgatc agtaacacca gagtttttga tatagacagt
    14401 gtttaattca tatgcactat tcatccgttt aaagatggta gcaattttta attgctcctc
    14461 gtttaaatta atctcatcag ctgtgacttt attgaccatc gcactatatt gttcgctgtt
    14521 ccctaattgc ttttcttttg ccgaaagtct ttttgtggct tctttcaaat gtttgggatc
    14581 agccagccaa aaatcttttt tatctctatc tgtcagattt tcatctaccg gaacatcgat
    14641 cagcgagttc agcttcgttg cgatttcaag caaatcttta gccgtaactt gtgttcctct
    14701 cgtatatgtg atggcctgat tcgctttatt cgtaactaaa gcttttcctg tggagtcgta
    14761 gatcattccg cgaggagtac tttcttggac cgtaatcgta gaagtagact tcactcgcgc
    14821 ctccatctct tcgccgttca cgatctgcaa ataacccaat ctagcaatca acgcaacaaa
    14881 taacgtaaat ataatgaaaa aaagaaaatt taagcgaaaa ggaacatggg accggcgaaa
    14941 cgttttgttc ttaggttctt gtgcaccttt tcttattttt tctaaccaag aagtatttaa
    15001 tatttttttc ataaaatctt tcatca
//
LOCUS       DAXLPC010000065        14119 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.065, whole genome shotgun sequence.
ACCESSION   DAXLPC010000065 DAXLPC010000000
VERSION     DAXLPC010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14119
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.065"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(31..3684)
                     /gene="rpoC"
                     /locus_tag="ACF3UE_001950"
     CDS             complement(31..3684)
                     /gene="rpoC"
                     /locus_tag="ACF3UE_001950"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFD3635333.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(3763..7380)
                     /gene="rpoB"
                     /locus_tag="ACF3UE_001951"
     CDS             complement(3763..7380)
                     /gene="rpoB"
                     /locus_tag="ACF3UE_001951"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFD3635334.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8108..9076
                     /locus_tag="ACF3UE_001952"
     CDS             8108..9076
                     /locus_tag="ACF3UE_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3635335.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9094..9999
                     /locus_tag="ACF3UE_001953"
     CDS             9094..9999
                     /locus_tag="ACF3UE_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3635336.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            9996..10802
                     /locus_tag="ACF3UE_001954"
     CDS             9996..10802
                     /locus_tag="ACF3UE_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635337.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10959..11927
                     /locus_tag="ACF3UE_001955"
     CDS             10959..11927
                     /locus_tag="ACF3UE_001955"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFD3635338.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12244..12768)
                     /locus_tag="ACF3UE_001956"
     CDS             complement(12244..12768)
                     /locus_tag="ACF3UE_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFD3635339.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13055..>14119
                     /gene="scm"
                     /locus_tag="ACF3UE_001957"
     CDS             13055..>14119
                     /gene="scm"
                     /locus_tag="ACF3UE_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFD3635340.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT         3997 a         3047 c         2784 g         4291 t
ORIGIN      
        1 taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca ttgcgtcttc
       61 tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg ctacaccgac
      121 ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga tgatcttacc
      181 tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga tcgcagcatc
      241 cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat ttgtttctaa
      301 tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc ctcctgagac
      361 tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac ctggtaagat
      421 atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa ccattacttc
      481 gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta cttcacgaag
      541 caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg gatcgattga
      601 tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt tcatacgtgc
      661 tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta cttctttggt
      721 acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg tgatcactgc
      781 ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac cttgagtgat
      841 atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag taccaggttc
      901 accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt cagagccagt
      961 tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac atgtgaagac
     1021 agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga tgtcttcgga
     1081 aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta cttctttacg
     1141 ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc cctcgcggat
     1201 ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga ttacatcttg
     1261 ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca aggctgtatc
     1321 ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg atagtccttc
     1381 acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg ccatcaaacc
     1441 acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag aatcagacat
     1501 catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga tgctgtcttt
     1561 tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga tcagaccacg
     1621 acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga tttcttgttt
     1681 ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg tcgaatgttt
     1741 gtaccctaag tctttcatac ggtcaagcat cttagaagtt tcttttactt tgaatcgttt
     1801 gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata ctaattcttg
     1861 ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt ccggtgtttg
     1921 gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag gcatgatctc
     1981 gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc attcagtaaa
     2041 tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat gaacatatcc
     2101 gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt cgccttcgcg
     2161 tccttcttct tccattgtca agtagtagtt acctagaacc atatcttgag aaggagtaac
     2221 aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca acatacgtgc
     2281 ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc catcgaaatc
     2341 ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt gtactaaaac
     2401 tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca gcaatactgg
     2461 gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac gttcgatttt
     2521 acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac gcatcacgaa
     2581 tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca tcttcaagaa
     2641 aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta gcaagttttg
     2701 acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg ggcggttacc
     2761 tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta ctgcttcttg
     2821 cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta acaaacgttt
     2881 caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac ttgttgcaaa
     2941 acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag ggataacgtc
     3001 cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa tatccaaacg
     3061 gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt tcaattcggc
     3121 tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg cacccatagc
     3181 agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt ctgtcaacaa
     3241 ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag caaaataaat
     3301 gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg aaggaatccc
     3361 tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca tgcgttcacg
     3421 gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc ctttataacg
     3481 gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa aaatccgctc
     3541 acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct caggtttttt
     3601 tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta tttgcatact
     3661 ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat ggcaaaccgc
     3721 aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta aattatcttc
     3781 tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt cagcagcttt
     3841 cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat caacagtgat
     3901 caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt cgatatccaa
     3961 gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga atgattccgg
     4021 tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt tcacacgtcc
     4081 gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg caccgtaagc
     4141 ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag ctttacctcc
     4201 caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca atttgtcatc
     4261 gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc catcaaatgg
     4321 ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac cggcttcacg
     4381 aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg ctacgtggat
     4441 acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga tgttcatacg
     4501 tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag gtaggaatgg
     4561 catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac gaccggccat
     4621 tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta acatgtttac
     4681 gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt gaacgatacc
     4741 gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt tttcgccaaa
     4801 gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg gcgtgacttt
     4861 ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac ccatttcgtc
     4921 taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt cttcaggtcc
     4981 taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag tgtatacgtc
     5041 atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc cttcccaagt
     5101 catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca tagatggtcc
     5161 gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg gacgttggtt
     5221 gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat ctaatgcacc
     5281 gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac catcatgttt
     5341 acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag taccaaccca
     5401 tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac ccatcaaggc
     5461 acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg caactacttg
     5521 tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt tttcactttg
     5581 agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg ggctgtttgc
     5641 ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt ggtcagtaac
     5701 acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga atttatttac
     5761 tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag gagtttcgat
     5821 cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac cggcgcggtc
     5881 acgagtcaat ccgccaggtc ctaaggcgaa aagacgacgt ttgtgtgtca attcgccaag
     5941 agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt ctttgatact
     6001 tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag tatcttggat
     6061 cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga attggttttg
     6121 taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat catcgacatt
     6181 gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt cggctggacg
     6241 aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt cacgttcagg
     6301 gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga ccacaccgtc
     6361 ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag ctagtgtttc
     6421 catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg tttctggatc
     6481 aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta attttttgtt
     6541 tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga aacgagcatt
     6601 cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac gttcgtaaac
     6661 gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt ctttttcgac
     6721 tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat cggaaccaaa
     6781 tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga tacgtacata
     6841 agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag ggataacagt
     6901 agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga cacctggtga
     6961 acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg ttccttgttc
     7021 tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc cagtctcgcg
     7081 gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat gcgcacgagc
     7141 ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca aagatagatt
     7201 gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc cctcatctaa
     7261 gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca acacttcact
     7321 gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt gtccagccaa
     7381 gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt tacaataata
     7441 tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg caaaaaaaaa
     7501 ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt gtttccttat
     7561 attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat agtttttgca
     7621 acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt tcttctgctt
     7681 tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga caattcttaa
     7741 ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga ggaacttcta
     7801 tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac tttagctact
     7861 ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt tgtatctatg
     7921 atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct aagtggctga
     7981 gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta ttttccgact
     8041 tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa ttaaggagga
     8101 aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac tagctttagg
     8161 aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa caattggcgt
     8221 attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca aagaaggatt
     8281 agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa atgcccaaaa
     8341 caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc ctgatttgct
     8401 acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca ctatcccgat
     8461 gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca atgaaaaacc
     8521 tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa tcggcttact
     8581 gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg gtgaagcaaa
     8641 ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg tcaaagtcaa
     8701 agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc tagctaaaga
     8761 tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa gtgttgtcgg
     8821 tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc aagtcaaaga
     8881 cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggcaaacaaa cagggatcat
     8941 ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa cagcgaatga
     9001 tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc cagacagcat
     9061 caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc tcttttctta
     9121 tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata cgtcactttc
     9181 cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg tgcagggatc
     9241 gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct aggcttttta
     9301 gggagtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa aattcccgcc
     9361 cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg tgtgatgggt
     9421 gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga gtcattcggc
     9481 ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat cgttgtatgt
     9541 ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac tggcgataat
     9601 ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat cggttatatg
     9661 atttctaatg gatgcattgc tctttctggc tccttgcttg cgcaaaacaa cggctttgct
     9721 gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat catcgcagaa
     9781 gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt aggtgcggtc
     9841 atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag tgattcgaaa
     9901 cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca gcaaaaattc
     9961 catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta acattggaaa
    10021 atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg aaaggcatta
    10081 atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg gctggtaaat
    10141 ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa attttattga
    10201 atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc agtcgcgtat
    10261 tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat cttgctcttg
    10321 ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa gaccgaacat
    10381 ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta tcctcagaaa
    10441 tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc acattacagc
    10501 gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct acttccaaaa
    10561 cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct tttatggtca
    10621 ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg catcaaggaa
    10681 ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc caattattag
    10741 cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt ttatcttcat
    10801 aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt ctctttcctt
    10861 ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt gttctctcct
    10921 tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa gacaaggtac
    10981 ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca cagcaactgg
    11041 aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca ggctatcgtt
    11101 ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat gcaaaagaaa
    11161 tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg ttgacttctg
    11221 aatctacgat gaaagatgcc aaactggcag cagctcaagg agattctgtt tcgaagttat
    11281 ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt ttcgctgaac
    11341 ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt gatgaattgc
    11401 ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct gtaaccggtc
    11461 gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa gtctgtggga
    11521 ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc atcattggga
    11581 tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa gaaaaagcca
    11641 tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc agcaaaatct
    11701 ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc tataaagaaa
    11761 aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact tatgtcggtc
    11821 ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa cagaagatga
    11881 gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta tcagatttca
    11941 caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca aaagactctc
    12001 cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta aaaatatcta
    12061 taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag tcatcagttt
    12121 acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata gaccatgggt
    12181 aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt tttagctagt
    12241 gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag agtgcatagc
    12301 agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg tccagttctc
    12361 gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa tagcaaaatc
    12421 agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga tctgctttgc
    12481 ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg gaaaccggct
    12541 ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa tctggaaatc
    12601 taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg gggctctatc
    12661 ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac gttcaaaccg
    12721 atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt attttcctcc
    12781 tttttattta tcctacttac tttttcctaa ttctaggata cctacttata tgttactaca
    12841 cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga ttgaaagaaa
    12901 aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt cattaatatt
    12961 ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa aagagtataa
    13021 taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa gtttactagt
    13081 cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag cggaaacata
    13141 cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg gcttgttagg
    13201 aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg cacatacaga
    13261 cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag agcttcatga
    13321 aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg ctaattcttc
    13381 aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta acgtggatgt
    13441 agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact taactccaga
    13501 tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg aatttgctaa
    13561 attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat atactgctgc
    13621 agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag ataccgggtt
    13681 tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc aaatcattaa
    13741 tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat tgaacgtaca
    13801 gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt cggatgcgaa
    13861 tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc cttttcaagg
    13921 aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg gaacgattat
    13981 aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg aaatatttat
    14041 cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat ctaccacaag
    14101 tgatagctca gattcatca
//
LOCUS       DAXLPC010000066        14118 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.066, whole genome shotgun sequence.
ACCESSION   DAXLPC010000066 DAXLPC010000000
VERSION     DAXLPC010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.066"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..556)
                     /locus_tag="ACF3UE_001958"
     CDS             complement(<1..556)
                     /locus_tag="ACF3UE_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HFD3635341.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
     gene            complement(572..1051)
                     /locus_tag="ACF3UE_001959"
     CDS             complement(572..1051)
                     /locus_tag="ACF3UE_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFD3635342.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1057..2081)
                     /locus_tag="ACF3UE_001960"
                     /pseudo
     CDS             complement(1057..2081)
                     /locus_tag="ACF3UE_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2098..3204)
                     /locus_tag="ACF3UE_001961"
     CDS             complement(2098..3204)
                     /locus_tag="ACF3UE_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFD3635343.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ACF3UE_001962"
                     /gene_synonym="adhC"
     CDS             complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ACF3UE_001962"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFD3635344.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ACF3UE_001963"
     CDS             complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ACF3UE_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFD3635345.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ACF3UE_001964"
     CDS             complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ACF3UE_001964"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFD3635346.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8175..8873
                     /locus_tag="ACF3UE_001965"
     CDS             8175..8873
                     /locus_tag="ACF3UE_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFD3635347.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9041..11680)
                     /locus_tag="ACF3UE_001966"
     CDS             complement(9041..11680)
                     /locus_tag="ACF3UE_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFD3635348.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ACF3UE_001967"
     CDS             complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ACF3UE_001967"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFD3635349.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            13523..>14118
                     /locus_tag="ACF3UE_001968"
     CDS             13523..>14118
                     /locus_tag="ACF3UE_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635350.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT         3959 a         3096 c         2543 g         4520 t
ORIGIN      
        1 aagcgcctac gagataacct cccataaaca aagcagagat cgaagcacca ccagcaacaa
       61 gtgaatacat gataaaagca gtacttggag gaatgaccat acctgtcgga gctgacgcga
      121 tattgaccgc tgtcgcaaac ttccggtcat atccttcttc cacttgctga gggatcaaca
      181 ctccaccaat cgcggtagaa gcggcaatgg ccgagctaga gatggaacca aataaagcat
      241 tccctaacac attcgtatga gccaaagccc ccggcacgcg cccgacgaac aacatcgcaa
      301 aatccactag tttcttagct atccctccat tattcatgat aatgcccgag agaacgaaaa
      361 acggaatagc gatcagcgaa aaactattga tacttcccac cattttttga gctgaactaa
      421 aagcagaaac atcaaacggt ataactaaca ataaagtcat catcgatgag aatgcaatac
      481 ttatagcaat cggcatccct aatacaagca acacaacaaa tacaaaaaat aacactaatc
      541 cggcttctat tgccatttta ttcctccatt tttatatttt ttcttgaatt gctggcttgt
      601 tgcttaatgt atcgattaga ttgatcaggc tatagataat gatgagtacc cccgatacag
      661 gtactgacag ataaacatat cccataggaa tacttaaaga aggcgagatc tgccccattg
      721 tcaatgtgac agcattccat ccgccataca ccatgatcat cgcagcaaat accagaaata
      781 aactttgaac aacaacttct aaaattttac tttttttgcc agttaatttt tcacttaaaa
      841 ccgttacggc taaacgtgct ttttgtccca caacatacgc ggaagacaac atggcaaacc
      901 agacaagacc gaatcgaaca agctcttccg tgaccgtatt tggatttcct aaaaccgttc
      961 tggaaaatac ttgccataaa acaacagcga ccatcccaac aagcaaaaca gctcccagga
     1021 tctctaatac cttgtttaaa atcattttca ttacagctac gctccttgct cttggatctt
     1081 ttgataaagg tctttgtagg taggatcgtt tttgaatata tcatgaagtg gggcaactgc
     1141 ctctcgaaac ggtgtattat ctacatcatt gaattggact ccatgttctt cttgtgctaa
     1201 agctttttct tcttcaattg cttttgcaaa agcttcaatt tcaaaaaccg ttgattcttt
     1261 cgctgcttct tcaatggctt tttcctgttc atcagttagc tgttctttga tggcatcatt
     1321 catgatgatg atatctggca cacgtgtatg ctcatcatag gaatagtatt tagctacccc
     1381 gccatgtcca gctgtataca agacaaattc attgttttct gatccgttga tcaaattgga
     1441 ttgaagagac gtgtacactt catcacttcc cataggtacg ggcgaaccgc ctaaaagctc
     1501 taccattttg atagcggttt cgctttgcat cacacggatc ttctttccct tcaaatcttc
     1561 cggcgtatgg atcggaccgt ctaccatata aaagctgcgc tgaccagaat cataataggt
     1621 caatccggta aatcctaaat ttttggtcga ttggtagatt ggctccatta tttcttcatt
     1681 atccatcacc ttaaagaaat gttcttcatc attgaataga taaggaacgg aaaaaatcga
     1741 ataatcttta gagaaacttt ccaacgctga ggcacttact tttgtgaaat ctactgctcc
     1801 tgactgtgtc aattcgatca gttcacgttc tccacccagt tgtccatctg ggaaatactg
     1861 gatctgtacg gaaccatctg ttttttcttt tactaaacgc ccaaattcat tcattgcatc
     1921 aattactggc tgttgcttgc ataagcaaag cgcaaggtaa ctatctcatt tacgtctgca
     1981 tctgcgacag ttgccacact agaattattt ccgcagccgc ttagacctag cagacctagg
     2041 ctaagcgaac ttgctgcaaa cagcagtgat gtttttttca tatgggtttc ctttctttta
     2101 acaataagag acgagcaatt ctgtcaaaca aagcaccgtt aacgactgtc cataaggcat
     2161 tgctgtgatt ccgatattcc gataaaaatc taaactgtcc cccattcctg tcccgattga
     2221 aacgttttga acttctcctt tttcatcgat ttgttcaagc aatccttgga tagcacgata
     2281 agcgacttct ttatattctt gtggtaaata acgtttatgg accgctttca aaataccgta
     2341 agcaaatcct gcagttgcag aagattctac gtaagaagaa ggatcatcca acaacgtatg
     2401 ccataaaccg ctttcagact gataagtttt taatgcacgc acttgtgctt caagtgtttc
     2461 gatcaataat ttgcgcaatg catcttcttt cgataattct aagatttcaa tgatctctgg
     2521 aatagcaatc gtcaaccagc agtttccacg agcccaaaat gcttcggcat agttatgatt
     2581 tccttcaaac gtccagccgt gataccacaa tcctgttcgt ttatccatca agtatttgat
     2641 atggatcata aactggtaac gagcttcttc taaatattct gggcgattca acagtttccc
     2701 gatttttgcc aaaggaagca ctgtcatcat caatgtatcg tcccacaact gattcttatt
     2761 ttccggtcca tatgtggcat gctgtaaccc gtcttcattt gtccgaggca tgtcattcat
     2821 gacccattct gcccattgtt ctaaataagg caaatagcgt gaatctttcg tgtcttcata
     2881 caagtaagcc atagtcaata gcggtgccat tgtattgacg tttttgggcg gagcgccttc
     2941 ttccatacga tcctcaaacc attcattgac cacttgataa gcgcgaggat tttttgtcat
     3001 ctggtaattt ttataaatac catatagacc gacaccttgt ggccaattcc acactgtcca
     3061 gcttttgtca tctactttca gtccatcaaa gtccaacaaa aattcaccat tatcgtcttt
     3121 gatcgttgtc aggttttcaa cgagcaggtc aattttttct ttcactaatt ctttaggtac
     3181 aaaaatctct tctttaataa tcatctttac gccacctttt taaacgcttt cattttatat
     3241 ccttaatata gcagtaatac cgtccactat aaatatcgct ttttgaacaa aaactgtcta
     3301 aaattgacct aaatgttaaa taacaaaagt aactttcagt tacttggaaa ttaaaaaaag
     3361 aacttggaga aacaacgttt tccaagttct ttttcatcta ttttcttatc ttttttctac
     3421 gctttctttt gcttatccgt tgtaagcatc aatgatgatc tgtttcaatt cagagatcaa
     3481 tggttctttc ggattagctg tcgtacattg gtcttcgtaa gctaattcag ccatacggtc
     3541 tacggttgta tctagtgttt cttgtgtgac tccttgagct tttagactca tgttgatgcc
     3601 gacagatttt cctaattcat aaacagccgt tgctaaagct tcgactaatt cctctgttgt
     3661 ttcgcctttc agacctaaga attttgcgat atctgcgtaa tctgtatctg cacggaaata
     3721 gtcatattta gggaacatcg catgtttttg tggatctttt gcattatagc ggataatatg
     3781 cggtaaaaga atcgcatttg tccgtccatg agggatcccg tattccccgc cgattttatg
     3841 tgcgactgag tgacaaatac ctaggaatgc gttagcaaac gccataccag ccattgtaga
     3901 agcgttgtgc attttttcac gtgattccat atcaggtgtt tttactgatt tttctaaata
     3961 gtcaaagact aacttgattg cttgtaggct caatccacgt gtataatctg aagccatgac
     4021 tgaaacatag gattcgattg catgtgttaa cacatccatc ccggtatctg ctgtgacaga
     4081 tgctggaact gacatgacga attgaggatc gacgattgcg acatctggcg tcaatgcata
     4141 atctgctaac ggatatttca catgtgtttc actgtcagtg atgaccgcaa atggcgttac
     4201 ttcagaacca gtccctgatg ttgtcgggat acatacgaat tgtgtttttt ctggtttgtc
     4261 gatcttatat gtccgtttac ggatatccaa gaatttttgt tttgcaccaa agaaagatgt
     4321 gtctgggtgt tcatagaaca tccacattcc cttagctgcg tccattgcag aaccgcctcc
     4381 aagagcgatt actgtatctg gcttgaagtc tgccatcagt ttcgttcctg cgtatacggt
     4441 atttgtcgat gggttcggtt caacatctga gaagacttcg atcttcacat catttttacg
     4501 tcgtgccaat acttcacgaa ctgtatcgca gtaaccgaat tggaccatac cagggtcaca
     4561 aacgatcatg acacgttcaa cgttttccat tttctctaag tacaatagag agttcttttc
     4621 aaagaagatt tttggcggta atttgaacca ttgcatgtta tttctccgtt tcgctacagt
     4681 tttgacattg attaagttta cagcagagac gttacgagaa acagagttct taccataaga
     4741 accgcatccc aaagtcaatg acggaatcat ttcgttatag atatcaccga tgccgccttc
     4801 tgcagatggt gtattcacta aaatacgaca agctttcatt cgaagaccga atttgacatg
     4861 caactcttcg ttttctgaat ggataactgc tgtatgtcct aatcctccaa gattcaacat
     4921 accttcacac aaatcaaacg catggtccgt gttgttagct ttgatcatgg caagaactgg
     4981 agaaagtttt tctcttgata gcggataatc tgggcctacg ccttccaatt cagcaatcag
     5041 cattttcgtt ccttttggta cactgattcc tgccaatttt gcgatttcca tcgcagaatg
     5101 tccaacgatt gatggattga ccgcatattt tccttcgttc atcactgcat cttctaattt
     5161 ttgcaattca tctggtttta cgatataaac ttggtgtgct tggaattctg cttttactgc
     5221 tgcatagatt tctttatcca cgatcacagc ttgttcagaa gcacaaatca ttccattatc
     5281 aaatgttttc gaaacgatca aatcgttcac tgcacgttta atttttgctg ttttttcaat
     5341 ataagctggt acgttacctg gacctacacc taaagctggt tttcctgtag agtaagcaga
     5401 cttgaccatt ccagctccac ctgtcgctaa gacgatcgcg atacctggat ggttcattag
     5461 catagaagtc gcttcgatcg aaggatgttc gatccattgg atacaatttt caggagctcc
     5521 ggcagcgata gcagcatcac gtaccactcg tgctgcttct gcagaagatt tttgggcact
     5581 tggatggaaa gcaaaaacga ttggatttct tgttttcaac gcgatcattg atttgaaaat
     5641 cgttgtggaa gtcggattcg ttgttggagt tactccgcaa accacaccga ctggttcagc
     5701 aatttcaatc aacccttttt ggacatcttc attgatcaca ccaactgttt tatcatgttt
     5761 gatattatgc caaatatatt cggacgcata catatttttg attgctttat cttcgtaaac
     5821 accgcggcct gtttcctcta cagccatctt cgctaatggc atatgttgat ccaaagctgc
     5881 cattgccatt tcatgcacga tatggtctac tttttcttga tcaaagcttt ccatttcttt
     5941 caatgctgca tttgcttttt ctgccaaatc atcaatcatt gcttgtacgt caattgtctt
     6001 cgttttttct ttttctatta ctttagccat cattatcctc ctaatgggtc atggttattt
     6061 gttaaataat tcacatgtat atcatacaat atttattttt ctatgtaaac acttttttgt
     6121 gatttttttc acagttattt ttaaatataa aattgcttta tttacaggtg tttgtataga
     6181 aaaatatata aagttattta ttattattta tatgacacac ccgattattc aatattgagc
     6241 aatatatccc atgctcttat ctctttcttt tttgaataaa aaatgaggta ggacatcttt
     6301 ctgccctacc tcgtctttaa ataagctttg atacttattt ttcttccttc tcttctgtct
     6361 cttccagcgt ttctgttgtt tcagttttta cttcaactgt ctcagctggt tcttctgttg
     6421 tttcaacagt agtcgttgca tcatttgtta cgacagtccc tggtttgacc gttttgattg
     6481 ctgcacgatc gtactcaagg aagatccctt cgcagtctaa aacaactgtc cgtttgtcat
     6541 tgtcgatttc tgaaacaact ccatgtaatc cgccgatcgt tacgactgaa tcacctggtt
     6601 tcatgctatc taacaagttt tgacgttctt gctgttgttt cttttgcgaa cgtgacataa
     6661 aaaaccacat tgctaatagc gcgataaaca tcacaagcat tggtaatgtt cccatttttt
     6721 tcacctcact aattctgtat ctacaaaaaa cactttagca gaaaaatgct gataacacta
     6781 gttttttact taatttttaa aagattttcc tttagaagct ttttgcgttt tctttattga
     6841 acccgtattc ttcaaaaaag gcttctctaa attcaagcaa attatcatcc atgattgctt
     6901 gacgtacttg tttcattaga ttcaacaaga agtataaatt gtggtaagaa gtcaaacgaa
     6961 tcccaaatgt ttcatcacat ttgatcaaat ggcggatata ggcacgtgta tagtttttac
     7021 atgtataaca atcacatttc tcatcaattg gacggaaatc atgggcatat ttcgcatttt
     7081 tcactactag acggccttga gaagtcatac atgtgccatt tcgagcgatt cgagtaggca
     7141 agacacagtc aaacatgtct actccacgga taacaccatc gatcaatgaa tcagcagcac
     7201 cgacacccat caagtaacgt ggtttgtttt cggggatcaa cggtgtagtg aattctaata
     7261 cacgattcat ttctgattta ggttccccga cagataaccc gccgattgag taaccaggga
     7321 aatccatccc gactagatct ttcgcgcttt gacgacgaag atcttcaaac cctgctcctt
     7381 ggatgattcc aaataatcct tgacggtctg gattagcatg agctttcaat cctcgttctg
     7441 cccatcgaga cgtacgttct actgattttt tcacgtagtc gtaactttca tcgaatggtg
     7501 gacattcgtc aaaactcatc atgatatcag agcccaattt attttggatg ttgattgctt
     7561 tttctggtga taaaaacata cgcgaaccgt tcaagtgatt tttgaaatgc acgccttctt
     7621 cttcgatatt ccgcatatca cttaatgaaa aaacttgaaa gccgcctgaa tctgttaaaa
     7681 tcggttgatc ccagttcata aatttatgca gtccgccagc ttcttctact aagtcttcac
     7741 cagggcgtag ccataaatga tatgtattac ttaaaataac gccagcaccc atttctttca
     7801 actcttctgg ggacattgtt tttactgtag ctaatgttcc tactggcatg aacattggtg
     7861 tggggaaagt tccgtgtggc gtgatcaatt cccctaaacg cgcgccagta tgtttttctt
     7921 tcttgattaa acgatagcga atggcaggtt gcgtcattca tttccctact ttctatataa
     7981 aatatcttga caactcccac catcataatc gtttcaagtg ctttttgcaa gttccctcgg
     8041 cttccttcta ctttatttaa tattcttttt tttatccttt ttttatgaat aacaaaaaaa
     8101 agaaaaacat tatgacagaa atattttttg atacatggta tattggtgtt attaaagaaa
     8161 aggagggaaa aatcatgcaa tcttctgcag aattaaaacg ccaagcaaaa gagagtctaa
     8221 aaggacgttg gggacaagct gttttactaa atctaatccc tacattgatt ggtattgcta
     8281 ctattcttct tattatgatt cctattatct tgtttgccac caccatatat gatggatcag
     8341 cgagcgtctc agaagcgaca acttcaggag gcggtagttc aggaggcggt ggcggaatta
     8401 tttccagcat cattagcgct ttgttcatga gcggtatttc ttggacttat cttgatattt
     8461 tacgtggaca aaaagatcag atcgaaccat tcaaagatgc atttcgtgga ttcaaaggtt
     8521 tgtttatcgg cggagtgatc agcttagctg tgctgatctc gatctttaca acattatggg
     8581 gtttgctatt agttattcct ggaatcatta aaagctattc ttattctcaa agctatttta
     8641 tttactacga tatcgtccaa gaaacaggac aaacacctaa agtactggat acgatcactg
     8701 caagtcgaaa attgatggat ggttataaag gacaactttt ctggttagat ctttcattta
     8761 tcggctggca tatcttagca ttagcaactg ctggtattgg ttatctatgg ctcagcccat
     8821 acatttctgc aacaaaagca gcattttatg aacaattgcc aaaagatatt taaaagagag
     8881 tgtgacttgt gaccgagggg gtggcaggag aacaccgttt atcgagaggc agtaaaagaa
     8941 acattcagcc cattagcaaa aaggaggtgt gacaacattc atgtcacacc tcctttttgt
     9001 atagttccag taaaaagaaa atcaacttag aaacagttaa tcattcctct tcttctgctt
     9061 ccggtaatcg atggaacttg atcagttcat tcaccgcgat tggtacgata gataaaatcc
     9121 ctaccaagaa ccagtgattc aaactgatgt gtactaggcc gaatagttct tgcgtaaatg
     9181 gcagcaaagc aacagccgtt gtaatagcta atgccagtaa cgccatttct accaaagctt
     9241 tattggtcgc taaattgact ttgaagatcg attggctgct gcgtacattg aacacatgca
     9301 gaatcgatga ataagctaag atcaagaatg caacagtttg accgacatgc tgacttgcgt
     9361 ctacccatgg gctgatagta tcgacataac tacctaaata ataaccaaac aaggttacga
     9421 tggtgaagac ccctgcattt atggcaattt tttgcaataa acctcgagca aagatccctt
     9481 catttttcgg aatgggtggc tgatccatga tgccgtgttc cgctggctct cttcctaaag
     9541 caaatcctgg aagtccatca gcaactacat tgacaaacag tagttgcaca gctgtaaatg
     9601 gtgctcccca tcctaacagc atcgcaatca aaacaataaa gatctccgaa atattacagc
     9661 ttagcaaaaa gttgatagct ttacgaatat tctgataaac cgaacgtcct tgactgacag
     9721 cgtctacgat cgtcgcaaag ttgtcatccg tcaaaatcat atctgcggca ctttgcgcca
     9781 catctgttcc tgtgatcccc atggcacacc caacgttact tgctttcaac gctggtgcat
     9841 cattcacacc atccccagtc atcgctacga ctgcacccgt acgttgccaa gatttgacga
     9901 tccggatctt gtcttctggc gttacccgag catagacaga gagagctttg acacgcgcat
     9961 ctaattcttc gtctgataat tgatgcagtt ctgatcctga aagtgcttct gacggatcat
    10021 tcaagatacc taattctttc gctatggcac tggcagtcac cacatgatct ccagtgatca
    10081 tgactgtttt gatgccagcc tttttcgctc gcttgattgc tcctttactt tctggacgtg
    10141 gtggatcgat cattccgatc agaccaatca aacgtaagtc tttttccagt gcttcagaag
    10201 aaatatcttg cggttcttcg tcataagtag cataaccaac agcaatcact ctcagtgccc
    10261 gtttaccaaa gcgatcatta acgatcgccg cttgttctac atcgcctgaa ctaaagcgcg
    10321 gagcaagaac atcgaatgct cctttggtga ttgagatgta tttttcgccc atttggtgaa
    10381 ctgttgtcat catttttcgt tcagaatcaa aaggaagctc gtttactcgt ggatattttt
    10441 cttctaattc tgcctttgta tgataattct cttcaacagc ccttacgatg gctacttctg
    10501 ttggattacc tttgataaca aggtcgtcat cttcttgctc gaccgtcaca tctgtacata
    10561 gtgcagccat tttcaatatt tccatcgcgc tgttcgtcat tgaatcttcg atattcgtta
    10621 cttcatcttc tttgctccat acccggcgga cgcgcatttc attttgtgtc agcgttcctg
    10681 ttttgtctga gcagataaca ttagcggttc ctagcgtttc aactgctggc aactgtcgga
    10741 tgatcgcatg tttcctcgcc atcttctgca caccgtatgc aagtgtcaac gtaacaataa
    10801 cagtcaaggt ttccggtaca gctgcaacag ccaaggaaat cgaagtcatg aacatctcaa
    10861 ggagtggttc tccttgcagt tcaccaatca caaatactaa agccgcagcc gctaaagcga
    10921 tcatactgat tcgtttgcct agctgattca atcggacctg taaaggtgtt ttttgcatag
    10981 tattttcgtt caaaagatcc gcgatcttac ccatttctgt agccatgcca atggcagtga
    11041 cgatcgcttt cccacgacct gcagcaaccg tacatccttt aaataccata ttaagttggt
    11101 cacctaatga ctcatcttct tcagcaataa atgctgcatc tttttcaact gcttcacttt
    11161 ctccagtcaa cgccgattct tctacacgta attgtgatgc ttcgatcaaa cgggcatcgg
    11221 cagaaatagc atcaccggac tctaaaacaa gaatatcacc cactaccagt tgctctgact
    11281 caacagtggt cactttgccg tctcgtatga cagttgccgt ttgtttattc atatcttgca
    11341 aggattccag tgctttttct gcgtttcctt cttggacaat cgccaatacc gagttgatca
    11401 caacgatagc gatgatcagc agtccttcaa ataaatcccc atgttctgta gcaaatgcgg
    11461 tataaaagga aatcaccgct gctacaagaa ggatgatcgt tgtaaaatcg gacaagcttc
    11521 gaaagaattt tttgatcatc gattctttcg gcgcctcatc gaatttattc aatccctgct
    11581 tttttcgccg ttcatccact tcttgtgaag acaacccagt atctggatct gcttctgtta
    11641 ccttctttac ttcttctatt gtctgcttgt attcttccat cctattcctc ctttaaaatc
    11701 ttcgtacaaa aaaaggtact tattttacta taacatcctt tttttattta cttcaaataa
    11761 agggcttatc gattatttgt taagaaagcg taaaatttaa agtgcttata tttgcaaacg
    11821 ctaccaaagg atgctattat atagatgtaa ggaaggagga taccatcaaa tagacagaag
    11881 aatttctcga tagaacagtg taagcaaaca aagttgttag aagtacaggt ttcacccaga
    11941 catgcgtgta gagtacaaac ctataaatag tgaatgcgta tggatgtttg gatcacgaag
    12001 tatccgaaac aagaagtaat gcgatacgta acaattgaat aacgtaaacg tctgaaaatt
    12061 gaataggaac aagagatgtt tcaaatgttg aagatgtaac gaaaacaaaa tttttgttta
    12121 acatgaagaa attcaacacc gtgctttgca tgtatgatgg aaagttacaa tcatttctgt
    12181 ttatttgaat ccttccgagg tacaagaaag ccgagcttat cgagagctcg gctttttctt
    12241 tgtcataaaa tctttgtaaa gcttttttgt tattcaaaac tagcggcttt tcataacctt
    12301 atttcacgaa catcgcatct ccaaaactaa agaaacgata gcgctcttca atcgcatgct
    12361 ggtaagcaga taaagtcaat tctcttcctg caaaggcact aactaacatg actaaagtcg
    12421 attttggcaa atggaaatta gttgagaaag cttctaccac tttgaattca tagccaggcg
    12481 taatgaaaat atcagtccat ccgctgtctg ctttgatttc tccattaaat ttcgttccaa
    12541 tcgtttctaa tgttcgaatt gaagttgttc cgacagccac gattttcccg ccatttttac
    12601 gtacttggtt caatcgctca gccgcttctt ccgtcaaacg gtagaattca ctatgcatat
    12661 ggtgttcttc aattttatct acgctgacag gtcggaatgt acctaaccct acatgtagtg
    12721 tcagatagac taattcaaca ccctttgctt cgatctcatc aagtaattct ttcgtaaaat
    12781 gcaatccagc tgttggcgct gcagcagaac cattttcttt cgcatagaca gtttgatagc
    12841 gatctgggtc ttccagacgt tctttgatat atggaggcaa tggcatttct cccaatgatt
    12901 caagaatctc tagaaaaatt ccttcatact caaagtcaat gatccgtccg ccgtgttcca
    12961 attcttcttt cactactgct tgcaatctgc catcaccaaa agagattctt gtcccaactt
    13021 tggcacgttt cgcaggtttg atcaatgtct cccacgtatc tccttgtgta ttcgttagaa
    13081 gaaggacttc taaatgcgca ccagtatctg gtttttctcc atataaacga gcaggcagaa
    13141 ctcgtgtatt attcataact agcgcatcac caggctgtaa ctcttcaatg atttcatgga
    13201 aatgtttatc ttccatctct ccagttttcc gatccaaaac aagtaaacga gaatgatcgc
    13261 ggtcttttaa tggtgtttgt gcgattaatt cttccggcaa gtcaaaatca aaatcttctg
    13321 ttgttaacat atcgtcactc actttctatc atgtgcttca tcattctatc atgtttttcg
    13381 ttctgttggc aaaatcagca ctttttcact tctatttttt gttttcctaa ataaaaaaac
    13441 taccctattt gtattttttc attgttttag gcatactagt aatagatagt tcttcattga
    13501 aaatagaaaa agaggtggca ccatgattga atttcaaaat gtgtcaaaaa tttataaagg
    13561 tggaaaagtc gctgtagagg acgtcaatct ttcatttgaa aagggtgagt tcatttgttt
    13621 tatcggtacg agcggaagcg gaaaaacgac gacgatgcgg atgatcaacc gaatgactga
    13681 tccaacacaa gggaaaattt tgattgatgg aaaatccatc caagaaattg atccagtgga
    13741 attgcgacgt cagatcggct atgttatcca aagtattgga ttgatgcctc acatgacgat
    13801 ccgtgaaaat atcactcttg tccaaaaatt gttgaaagtc agtcaagaag aacggaataa
    13861 aacagctgaa aaaatgattg atcttgtgga attgccccgt gagatgttag atcgctaccc
    13921 acatgaatta tctggtggtc agcagcagcg tattggagtc gttcgtgccc ttgcagcgaa
    13981 tcaagatatc atcttgatgg acgagccatt cggtgcgctt gatccaatca ctcgtgattc
    14041 cttgcaagac cttgtcaaag atttacaaga gcgtttggga aaaacgatcg tatttgtaac
    14101 ccatgacatg gatgaagc
//
LOCUS       DAXLPC010000067        13936 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.067, whole genome shotgun sequence.
ACCESSION   DAXLPC010000067 DAXLPC010000000
VERSION     DAXLPC010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.067"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(26..319)
                     /locus_tag="ACF3UE_001969"
     CDS             complement(26..319)
                     /locus_tag="ACF3UE_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HFD3635351.1"
                     /translation="MELTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(347..1012)
                     /locus_tag="ACF3UE_001970"
     CDS             complement(347..1012)
                     /locus_tag="ACF3UE_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFD3635352.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1152..1784)
                     /locus_tag="ACF3UE_001971"
     CDS             complement(1152..1784)
                     /locus_tag="ACF3UE_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3635353.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDCPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1791..2858)
                     /gene="liaS"
                     /locus_tag="ACF3UE_001972"
     CDS             complement(1791..2858)
                     /gene="liaS"
                     /locus_tag="ACF3UE_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFD3635354.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEIAKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2855..3586)
                     /gene="liaF"
                     /locus_tag="ACF3UE_001973"
     CDS             complement(2855..3586)
                     /gene="liaF"
                     /locus_tag="ACF3UE_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFD3635355.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            complement(3754..4233)
                     /gene="greA"
                     /locus_tag="ACF3UE_001974"
     CDS             complement(3754..4233)
                     /gene="greA"
                     /locus_tag="ACF3UE_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFD3635356.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4369..5544)
                     /gene="mltG"
                     /locus_tag="ACF3UE_001975"
     CDS             complement(4369..5544)
                     /gene="mltG"
                     /locus_tag="ACF3UE_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFD3635357.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPNGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEKAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            5709..6869
                     /locus_tag="ACF3UE_001976"
     CDS             5709..6869
                     /locus_tag="ACF3UE_001976"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFD3635358.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KESNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            complement(6909..7856)
                     /locus_tag="ACF3UE_001977"
     CDS             complement(6909..7856)
                     /locus_tag="ACF3UE_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFD3635359.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDME
                     KQVTFIEGDVSDPQLMERIMKQYQFAYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFASEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(7989..9380)
                     /locus_tag="ACF3UE_001978"
     CDS             complement(7989..9380)
                     /locus_tag="ACF3UE_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFD3635360.1"
                     /translation="MLNEKFLKYVKGWYFIYFGFILMLRAIGPYLLLPTRYDTLLFWP
                     AGIAGVVLIIIDAIIAFREKNLKKYDWLLIAFIGAMLVSSLMNLKYGYSENIKLIMWQ
                     LIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLANLVSLYWFVIQYGIKIPIKYKYYP
                     VRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYLVTYKHLNLLFKIFFAINIFIQFS
                     FIALSGSRTTLVCLLIATFVFSFFTSYSSRFLKTNTLKRWLTALVVGLLSIIAMYYVT
                     DITAQAWAHVPHITEIKKDISDSSGTTSSNKVDLKRPDTDGGDVSNLRFGLWKSAIEI
                     FKSKPISGGSPGYYIEYAHDKLPYTLMGKDTLTAHNFIFLVMAATGGLGLLTLLTFLF
                     IQCFKTLRYCFTQPNLVKDKHFFAILMILTIAVSALFITELILVSTIGSFIFWGYLGS
                     IQKTISKEEGVTN"
     gene            9506..9916
                     /gene="tagD"
                     /locus_tag="ACF3UE_001979"
     CDS             9506..9916
                     /gene="tagD"
                     /locus_tag="ACF3UE_001979"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0047348 - glycerol-3-phosphate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HFD3635361.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGQFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            10330..11130
                     /locus_tag="ACF3UE_001980"
     CDS             10330..11130
                     /locus_tag="ACF3UE_001980"
                     /inference="COORDINATES: protein motif:HMM:NF013753.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFD3635362.1"
                     /translation="MRLRKQHYHYQSCGKYFTAHTYLVVPSCFISKQVHYTILEELTE
                     RQALKTLTKRCDLSVTTFQRTLSALSAMLRQMLDYLPHCLLFDEFRSLSISHGKFSFS
                     CMNRETGKLFDILSSRRKKDLIAYFMRFTRKAHMGVRYIVTNMNAPYFSLVKESFPNA
                     QIIIDCFHIGQHLNKFFDRVRKRVMKQLNQKDTSQAKYYRQLKPLYKLLLKSDDELDY
                     TTFKKWQNFQWRYLTESEVVDRLPSISYELKIAKQFIKSCLAIITRNS"
     gene            11239..11385
                     /locus_tag="ACF3UE_001981"
     CDS             11239..11385
                     /locus_tag="ACF3UE_001981"
                     /inference="COORDINATES: protein motif:HMM:NF013753.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3635363.1"
                     /translation="MTKLENLRTHIKTLKRFAYGFRSFTNMRLWIFLINRLISYALKA
                     SNSY"
     gene            complement(11452..12879)
                     /locus_tag="ACF3UE_001982"
     CDS             complement(11452..12879)
                     /locus_tag="ACF3UE_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFD3635364.1"
                     /translation="MKKTVKDIFYNAIYQVFLIVLPLLTIPILSRRIGSTGLGIYGYV
                     FSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQFWNIYFIQFLIGLSVSFLYIAY
                     IYFFDVKYKNLYLIQLIFIVGLTLDISWFFQGIEEFSKVVIRNTVIKLSSVLLIIIFV
                     STKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPIFNSNVFKQLWKPAFIILTPQLF
                     MQVYTTLDKTIVGYFVDPTELSYYDQSQKIARIILAVLTSITIVMLPKISKAQAEGKS
                     ENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWFFGENFKPMTINMLISCLIIVVS
                     PIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNVAFVPTYGAVAATIVLVVVELLV
                     FFFRVFFVRKEIKISYFFGKNVILFFIVNLTLTTWAYYFLPQLFSSSFLDMAIKSIMI
                     FIIYLPFVYFLFPDIRNEIRKITRK"
     gene            complement(12876..>13936)
                     /locus_tag="ACF3UE_001983"
     CDS             complement(12876..>13936)
                     /locus_tag="ACF3UE_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HFD3635365.1"
                     /translation="FSSFGGRNYSGNPRVISEKIHEKKLNYRIIWLIKKEAIITDLPD
                     YIKRIDSDSFLAAFYLYTAKYWIDDSRKTIKYAKRKKQLYFQTWHGTPLKKIEFDAKD
                     KLPKRYLSYAKKDSESITYLLSGNRYSSKKYVSAFNIVPSKILEVGTPRNDELASSKE
                     QVFDLKKKQINVLFAPTFRNNIEDNGITQLEWLGVDNLREFFKKQQQELNFMTKFHPN
                     VHSKLATDSKSIEYMKKHQITLINDGIPLEMLFEEIDVLITDYSSIFFDFALTKKPII
                     LFNYDEKEYSLERGFYIQLSELPIISVQDSYGLVDVFKNQQEKLLKSSQELLDYIGNY
                     ETGASTEKVLELIERDIK"
BASE COUNT         4550 a         2675 c         2068 g         4643 t
ORIGIN      
        1 aaaacttgtg tcaccctctc tttttttatt gttttttaaa gtgataggtt ggctcctcca
       61 ggttgggatc ataatcaaca agtaaatcat atcctttaaa gaaccattca tctgcttcct
      121 cgataaaaaa aagtgtccca tccatttcca ctttctttac aggatgttct ggctgttcaa
      181 ctgacattcc aatcgaaaaa ccatcatgaa cctctgtttt gccgtagact tttccaaaaa
      241 aacgtattcc gtaagtttct ggcagatcaa tttctgagtc aaaccacttt tgtgcttttg
      301 gcgttaccgt taattccatc ccaacaacct actttctctt ttctttctat tgattcatct
      361 tatcgtctag aatatccaca tcgcctgtct ctccaatcac cagtagatta tcattttcgc
      421 gaacatattc atctgctgca ggagaagcga taaccgtttg atctactctt cgtatggcga
      481 ctactgttaa gtcaaaacgt tgcctgaaat ttaattcagc taatgttttg ttgaaaaatt
      541 taggattgga gactcggatt tctgctaaag aatatttatc tgacagctct aagtagtcta
      601 gaatattctt tgatactaag ttatgtgcaa tccgtatccc catgtctcgc tcagggtgta
      661 cgacacgatc tgctccgatc ttctctagta cacgggcatg gtactcattt tgggcttttg
      721 ctaaaatatt cggtacgccc atttccttta ccatcagagt aactaagata ctggcttgga
      781 tatcttctcc aatagcgaca attacatgat cgaaatttct tatacctaat gaacgaagtg
      841 tcatctcatc ctgtgcattt gccacaacag catgagtggc tatattcata tattcattga
      901 ctcgatcttc attactgtca atagccagta cttcttgtcc agcttcgatc agtgtacggc
      961 agatgcttcc gccaaatcgt ccaaggccta caattgcaaa attttgtttc accattttcc
     1021 tcctttagta tcttcttttc tcagtataac aaagcctttc caaaaacaaa agcaagcatc
     1081 attattgtaa aaaagccaag aaaaataata gttattttct cagcttttga ttatcctctt
     1141 tatcatcgtt tttatttcac caaaccatgt ttaaacgcat agatagctgc ttgagttcgg
     1201 tcttctacct ctaacttagc taatatattc gacacatgcg ttttaactgt tttcagtgtg
     1261 ataaacaatt catccgcgat ttcctgatta cttttccctt cagaaatcag catcaaaatt
     1321 tcattttctc gattcgttaa ttcttcatgc aatactggat catttcgccg actcattttt
     1381 tccatcattt ttgttgtcac ttcaggttcc aatactcgct cgccgcgttg cgtagccctt
     1441 atagcatcag ctatttcatg tgcggtagac gtcttcaaca aatatcctgc tgctcctgct
     1501 tcaattgcag gataaacttt ttcatcatca ataaaacttg tgacgataat gattttggct
     1561 tttggacaat cttttaagat tgcttttgtt gattcgatgc catccatttc ttccatgact
     1621 agatccatta aaatgacatc tggtcgaagt gccatcgcct tttcatagcc ttgacgtcca
     1681 ttttcagctt ctccaatcac ttcaatgtct tcttggatag ataaataaga agagacgcct
     1741 aagcgtacca tttcatggtc atctactaat aaaactttta tcatctttat ctatgcctcc
     1801 ttcatcaaag ggaccttgat ctccacgctc gtaccttgcc ctttaaaact aatgattttt
     1861 actgttccac caataccagc tactcgttct ttgatattgt tcaatccata acttcccgtt
     1921 ttggtttcat tcatattaaa tcctgtcccg tcgtcaatga tacgtaataa aagattgtta
     1981 tctattttat gcaaatagac ttctaattca ttagccttag catgtcttaa tgtgtttgat
     2041 aacaattctt gaacgattcg gaacaagtga tcctcaatgg aactagttaa ttttacatct
     2101 tctacatccc attttagcga aatctggatt ttattctgca attccttcaa taactgctca
     2161 atgccttgtt ttaaactttt ttcttctaaa ttgactggac gcagatgaag aagcagcgca
     2221 cgcatctcag actgggaagc gttgatgatc tctgccacca ttttcaactg cttacggaac
     2281 atttctggtg tctcactttt ttctgcttgc tccgtcaatg ccgacatcat catcatcgct
     2341 gcaaataatt gctgtgaaac tgaatcatga agctcacgag ctaatcgatg cctttctaat
     2401 tctaaaatct cttctttggt ttgtccatct acatattgag gacggctagt cataatctgt
     2461 aattcactgg atacttcgat cattttttct tttattttag caatttccat atcaatatct
     2521 ttgatgtaca gatcatccga cgcgcttggg atcggctgat gcaaaagttt ggattcataa
     2581 ttgccagaag aaagtgcacg aagcttttct tcgattttcc cgtattttgc cttttgaata
     2641 agtgataaca atagaaatac gatcaatcct acacctaatg aaattgccat caaatggaag
     2701 ataagcggaa cgtataataa acgcgcacgc agcaattctc cccaccaatg actttggtta
     2761 ctggcataaa aataagtgaa aagtgaaaat agaataataa ggaaagccgc aatccccgaa
     2821 taaacagcta gcattgcttt ggatattctt cccatcatat tcgtatcacc tcgacatctc
     2881 caaccaaggt attggtaatg atcttcaatc tgcgaggatt ttcatcataa tcactgctgc
     2941 agattttgat ctgttcgttt tttaaggaaa actgctcttc ttcaaacaag acatttccta
     3001 ctaatgtcgc atgctctaaa cgaatagcca ctcccagggg tactaagatc cgtgttctgc
     3061 ctatcccttt tcttacaatc acaatattat catcttttgg caaaagtgta ttacccaaat
     3121 cgatgatagt atcaccagaa atgatggcaa tgttgatatc atcccattca tagacgtcgt
     3181 ttccaatacg ttggttacca aataattgct gtcttttacg ctcattatta tgtgttttta
     3241 attgctctgt ttggaccatc atgatctgtt tttttcgcca aaaagcattt tttgtcaaat
     3301 ctattcctga aatctctaca cctttcagcc cgataaataa aacggccaat acaaccatca
     3361 tccataaagc aggactgttg actaagctaa aaaaaatgac caagctccct aagatcaatt
     3421 gaaaattttg aaatttagta cgaggatatt tgcgcatagc tagatatata ttgaaaatac
     3481 cgaatattac taaaagcaaa agtccagtat tgtttacgat ttgccaaaca gcaaataaca
     3541 gcagcagtgc ttcgactacc acaaaaaaac gccaagaact attcatcgct ttttctccct
     3601 cctgacacat tctcatttca tcatacctat ttttttgact gttggctata ggactttaga
     3661 tgtaagatcg ttcagtgaaa cctgcaatac tcaaagagaa aagatctaga gtgcgtcatc
     3721 agtaagatga actctctaga tctttcagtc agactacgct tgttctactt tgacgatttt
     3781 aactaacata tcgccacctg gtgtagcaat ggttacttca tcatttttac gtttgccaat
     3841 caatgcttgc gcgataggag aatcattgga aatctttcca gaaaacgggt ctgcttcagc
     3901 acttccgaca atcgtgtact cttcttcatc tccatcaggc aactcgatga acgtaactgt
     3961 tttaccgatc gatacctcat ctgcatctac gccgtcatta tcgatgattt gtgcaaaacg
     4021 gatcatattt tcaattgttg tgattcttcc ttcaacaaat gcttgttcat ctttagctga
     4081 ttcgtattcg gagttttcgg aaagatctcc gaaaccgcga gcgattttga ttcgttcaat
     4141 gatttctccg cgtttaactg tttttagttc ttctaattct ttttctaatt tttctttacc
     4201 ttctagagtc attggataaa ctttctctac catgtgtaac gtctcctttt ttcgataaaa
     4261 taccgcaaaa ggtaatcttt tgaggaatat agtccaaaaa agattaccac gcttttctta
     4321 aaatgtaaat gtttttctaa aaatgatcaa tgactagccc ctgtttttct aagaattatt
     4381 tacatatttt tgcactagtt ccatatgttc ttcatacgtt ttagcgaaat aaacatttcc
     4441 agtgctcgta tctgctacga aataataata gtcattttct gctggttcta atactgcctt
     4501 gattgccttt tcgcttggat tgtcaaaagg accaggccca tagccggtat tggtatacaa
     4561 attgtatggt gaatctacag ctgtatcttc atacgtcacc aattctttat gttctcctaa
     4621 tgcatataaa acagagatat ctgactgaag tggcatattt gccttgattc ggttaaagaa
     4681 gacttgtgca atatttttac gatcattttc ttttacgcct tctttttcaa ctagagaagc
     4741 caaagttaaa acttcttgta cagtcaaatt tttctgtttg atagctgaat aatagttttg
     4801 catgaccgta tttgtcttgt tcaccatctc aatcacaaga tccttaagcg aagtactcgt
     4861 gtagtaatca taagtagctg ggaataagta gccttccaaa cggtattttg tgttctcagc
     4921 tttagaggca ctttccaaca attctgggaa tttttgatac aactcgttaa agaaagtctc
     4981 atcatttact aaatctaaaa attctttctt gtctttacct gttaccttcg ctacccgctc
     5041 agcaatctga tcgatgtcgt agccttctgg aatggcaatt ttcccatctg caacttttgt
     5101 tggctcagat gtgccgcctt cttgcaactg cttgccaatc tcatcaagag tcatattagg
     5161 cgctaactga taataaccag cttgaaagcc agttaagttt ttaaattttg tataataatt
     5221 gaaaacaatc ccacttttaa taatattgtc tttctccaaa atttcgccaa tctgcttatt
     5281 agaagagccg tttgggattt ccacttggac taattggtcg tccgatttat ctaaaggctt
     5341 caacccgcta tctacataac gatatacggt aaacccgaga aatccgccaa taatcaataa
     5401 tgtaagagcg atcactaaaa tgatcttcct cacgatctta tcttcttttt tacgcagatt
     5461 tctccgcttg tcgattatat ctgctgtagc tgccttactg gcttcttttt tgtctttgct
     5521 tgggtgttgt ttgtttcctg acaaaacaac tcctccttac tatcatcttc gtaactctgt
     5581 ttattataca tgaaatttct actgccgtga attattttac caaatattat gtcaaaattg
     5641 taagtggcaa atgctctttt tgaggattac aatgaaaaat agttaaaaat ggatagaaag
     5701 gatttaatat ggcaaaagga aaacatcaaa aaaaacagca gatctctctt tcttttctcg
     5761 cagttttgtt gctggctgtc agcttctttt caacaggcat cattacagga tggcaattaa
     5821 caaaacaacc tcaaccacaa atttataaaa cggaacccgc acaacttgct tccaatttaa
     5881 catctaatga gcagatgctt gccagcaaaa ttgatcaatt actgcaaaaa tcagattata
     5941 tcggttcgat ttatgtacgc aaaaataatc gagtgatatt agaaaaagga tatgggtacg
     6001 caaatctacg cataaaagaa tcgaattctc cttctcttta ctatcaaatc ggttcgatcc
     6061 aaaaagcgat gactgcttta cttatcctaa aacaaattca atctggcaag ataacttttg
     6121 acacaaagct atctgaattt tatcctcaga ttcctggaag tcagcaaatc tcaatcaaaa
     6181 atatgcttta catgcgctct ggtcttcatc gaaccgcttc tccaaaaaaa cctatgtcag
     6241 atagtgagat cattcagttt gcccttcatc atttgaaatt tactggttat gatacgtatc
     6301 attatgaacc attaaattat acattgctta caggggtatt gatcaaacta atgaatcagc
     6361 cttatgaaac tcttttaaaa aaagaaatca ttcggccact ccatctagaa catacagatt
     6421 tttatgaaaa tgtaaaaaat tcccctcagc atgctgtatc ttaccaaatg tctgcaactg
     6481 acgattattc aaaagcattg gtcgagcctg aaacagacat ccgaaatgaa ttaggcacag
     6541 gaaatataag tatgtctgtt tatgacttga acaaattctt taccagtgtt ctgtctggcg
     6601 atattatacc aaaagaacta cttttctcat tgtggcaaaa taatggtgat aaacatcctt
     6661 acagcggcgg tgtttacagt ggaaatgatt atatccttgc tcagggaaat atcaatcgat
     6721 tccatgcagt agcggcgatg aaaaaagaca caaaagatgc aatcgtcatg gaaagtaata
     6781 tccaatctga taaaaacatc aaattgccgg ccactgattt aagaaatcag atttacgaac
     6841 tgatggaagg tgttaattta aaaagctaag tcgagacaaa aaaaccagca ggatgctggt
     6901 tttttgtttc aatcgatttc tgtctttaaa taacgttcca ttccgttcaa tatatcaaat
     6961 ttgggttgat aacctaaaga acggatcttt gaaatatccg ctaaagaatc acgaatatcc
     7021 cctgaacgct ccgcttcata tttaagcgct agctctgttc ctaagatttg atcaattgaa
     7081 tgaatcaatt caagtagcgt agtgcttttt cctgtaccga cattgaattg ctgtcctaaa
     7141 gctttttctt ccttagcaac aagtaaaagt gcttgtataa catcttctat ataaacgaag
     7201 tctctagatt ggctaccatc accaaataaa gtaaattctg ttttttctcc tgccaattgt
     7261 tttttgtatc ggtccactag aatcgaaata actccgctat atggagagtt aggattttga
     7321 tttggaccat aaacgttaaa aaatcggaca gcactagtcg gaacatcata taaatgacag
     7381 taatccaaaa catattgttc tgatgcaaac ttatcgatgg catatggtgt taaaggacgg
     7441 atgaccgatt cttctttttt tggcaacgtt ggttcatcgc cataaactgc agctgatgaa
     7501 ctaaatacca atcgttttaa accagattga tattttcgta ccaattcaag caataaaagc
     7561 gcactgtcaa aatttacacg atgagtttct agaggacgtt ctacagaatc tgccacacta
     7621 gctacagcag ctaaatgaaa aatataggca aactgatact gtttcatgat tctttccatc
     7681 aattgaggat ctgatacatc cccctcaatg aaagtcactt gtttctccat atccaagttt
     7741 tctttttttc ccattgataa atcgtcgact actacgattt tgttttcttt tcccaaataa
     7801 ttcgctagcg ttgaaccgat aaaaccagct ccaccagtaa tcaatatagt atccatcaaa
     7861 ttcactccaa ttatgcattc tcatacttaa taaagttagt ttaccatttt tatattgtaa
     7921 aaactataaa atttgttgaa gttgggataa ctagttttct tttctacttt atatacctaa
     7981 aaatagtttc aattagttac tccttcttct ttagatatag ttttttggat agaacccaga
     8041 tatccccaaa aaataaatga acctatcgta ctaaccaaaa tgagttctgt gataaataat
     8101 gccgaaactg ctattgtaag aatcattaaa atagcaaaaa agtgcttatc ttttactaga
     8161 tttggttgtg tgaaacaata acgcaaagtt ttaaagcatt ggataaataa gaaggttaac
     8221 aatgtcaata gacctaatcc tcctgtagca gccataacta agaaaataaa attatgagca
     8281 gttaaagtat cttttcccat taatgtatat ggtagtttat catgtgcgta ttcaatatag
     8341 tatcctggag aaccgccgga tatcggctta ctcttgaata tttcaattgc acttttccaa
     8401 agtccaaacc ttaaattaga aacatccccg ccatcagtgt cagggcgttt taaatcaact
     8461 ttattgctgc tagttgttcc tgatgaatca gatatatctt tttttatttc tgtaatatgc
     8521 ggaacatgtg cccatgcttg agcagttata tctgttacat aatacatcgc aattatactt
     8581 agcaatccta ctactaatgc agttagccat ctttttaaag tattagtttt aagaaaacga
     8641 ctactataac ttgtaaagaa actaaaaaca aaagttgcta ttaataaaca aactaatgtg
     8701 gtgcgtgagc ccgataaagc aataaacgag aattgaataa aaatattaat tgcaaaaaat
     8761 attttaaata gaagatttaa atgcttgtaa gtgaccaaat aatatatagc aataatgatg
     8821 acaattaatg atataaccgc accaaaattt ggatctgtat atacaccaaa taaacggttg
     8881 cctaaccacc ctaaacgaac tgggtaatac ttatatttta ttggaatttt tatgccatat
     8941 tgaatgacaa accagtataa tgatactaaa ttagctaaaa accataccaa tgaaagtatc
     9001 caagtaaata ctttgaaaaa aaagttacta ctgtagtctt tgccaaactg ataaatcata
     9061 aagaaaaaga ttaattgcca catgattaac ttgatatttt cgctatatcc atattttaaa
     9121 ttcattaaac tgcttactag catcgcgcca ataaaagcaa ttaatagcca atcatatttt
     9181 ttaagatttt tttctctaaa tgcaataatt gcatctataa tgatcaagac aactcccgct
     9241 attccagcag gccaaaaaag taaagtatca tatctagtag gtaatagtaa atacgggcct
     9301 attgctcgta acattagaat aaaaccaaaa taaataaaat accaaccttt cacatatttt
     9361 aaaaattttt cattcaacat ttttcctcca tccacctatt tctcataaac atttcttatc
     9421 ctttttagga taaactggtt ctttcaattc taacaaaaaa atgctaaact aacaatgtat
     9481 attaatgaat ttcgagaggt gaaagatgaa aagagtaatt acttacggta cctttgattt
     9541 gcttcactac gggcatatca atttactgaa acgagcaaaa caatatggag attatcttat
     9601 tgttgccctt tctacagatg aattcaattg gaatgcgaaa caaaaaaaat gttattttag
     9661 ttatgaaaaa agaaaacagt tacttgaagc tattcgctac gttgatttag ttattcctga
     9721 agaaaattgg gaacaaaaag taaaagatat aaaagaatac catgcagatt atttcgtgat
     9781 gggcgatgat tgggctggac aatttgatga acttgaacaa ctaacagatg cacaagtaat
     9841 ttatttacca agaacacctg agatctctac aactcaaata aagaacgaac ttaattcttt
     9901 aaatagtgat aaataatatt ttttaaacaa tgaaagaaca atatatctgg ataagacgta
     9961 aaaaaatggc tctataattt ctaggactga tagaattttc tgtcgatcct agattttctt
    10021 gtaaaaaaaa cagacataca aaaatttcga taaaatagag tcgtctaaaa catcaatctg
    10081 aaaggaagat tttgtatatc catttctcgt tctatcaaag agcacttcac tattaaagat
    10141 aaaaatattg aaattaattc ttttcaaaaa actttttata aggacaagaa agccatcgta
    10201 atcgaaggta cattagttcg cacttttaga cattgtctat tttgtaaaga aactgcgaag
    10261 cagctcgtga aaaacggcaa gaagatttca atgattatct taaatcgcag tgggaataaa
    10321 taaacctatt tgcgtcttag aaaacaacat taccactacc aatcatgcgg aaaatatttt
    10381 actgctcata cgtatcttgt cgttccttca tgttttattt cgaaacaagt tcattacacg
    10441 atattagaag agttgaccga gcgtcaagcg ttaaagacac ttacgaaacg ttgtgatctt
    10501 tcagtaacga catttcaacg gacattatct gctctatcgg caatgctgcg acagatgcta
    10561 gactatttac ctcattgttt actattcgac gagtttcgct ctctttcaat ttcccatgga
    10621 aagttctcct tttcttgtat gaatagagag acagggaagc tctttgacat tttgtccagc
    10681 cggagaaaaa aagatttgat tgcttatttc atgcgtttta caagaaaagc tcatatgggg
    10741 gttcgataca ttgtcacaaa tatgaatgcc ccttattttt cattagtcaa agagtccttt
    10801 ccaaacgccc aaatcatcat tgattgcttt cacattggac aacacttgaa caagtttttc
    10861 gatcgtgttc gaaaacgtgt gatgaagcag ttgaatcaaa aagacacttc acaagctaag
    10921 tactatcgac aattgaaacc tttgtataaa ttacttctaa aatcagatga cgagttggat
    10981 tacacaacat tcaagaaatg gcagaatttt caatggcgct atttaacaga aagtgaagta
    11041 gttgatcgtc taccctcaat ctcttatgaa cttaaaattg ctaagcagtt tatcaaaagc
    11101 tgcttagcaa ttatcacaag aaacagctag ctacttcgag aaacgaccaa agaagttccc
    11161 tcgaaacttc actatctcaa aaagcctttt tcatatctga aaaaggcttt taactagcat
    11221 tttcgaaaaa gtattctaat aacaaaatta gagaatcttc gcacacatat caaaacattg
    11281 aaacgatttg cttatgggtt tcgcagtttt accaatatgc gcttgtggat ttttctaatc
    11341 aacaggttaa tcagctatgc attaaaagct agtaactctt actaactttg ttgttcataa
    11401 atgaccttat cagcccgatt tgacaaagaa ctactttttt acaacattat tttattttcg
    11461 agtaatcttt cttatttcat ttcgtatatc tggaaaaaga aaataaacaa acggaagata
    11521 aataatgaaa atcattattg atttaattgc catatctaaa aatgaagaag agaataattg
    11581 tggaagaaag taataggccc aagtagtcaa agtaagattg actataaaaa ataagataac
    11641 gttcttccca aagaaatagg atatttttat ttcttttcgt acaaaaaata ctctaaagaa
    11701 aaagactaat aattctacta ccacgagtac gatcgtagcc gctacagcgc cataagtagg
    11761 cacaaaagct acatttccaa taatacttac aatcgcacca atgatcattg gataagcata
    11821 ctccttatct ttttctatag caattgcaaa ttggttagca aaaactccac caattggact
    11881 aacaactata attagacaag aaataagcat gtttattgtc atcggtttga aattctcccc
    11941 aaaaaaccat ggaacaaatt cttttgtatt gataaacacc acactaaaaa gaattaatgc
    12001 aatgataatc gtgtaatcaa aagatttttt tgtgtaaact aaaatatttt ctgatttccc
    12061 ctctgcctgt gctttagata ttttaggcaa cataacaata gtaattgatg ttaagactgc
    12121 caatataata cgagcaattt tttgagactg atcataataa gataattccg ttggatccac
    12181 aaaataccca actatcgttt tgtctaaagt tgtgtacact tgcataaaca actgaggagt
    12241 caaaataata aaagctggtt tccacaactg tttaaaaaca ttagagttaa agattggttt
    12301 acctactttt ccgtggatac ttaaccagaa aactaaactt cctaaaaagt tagtaattga
    12361 agtaatgaac acgtaaatcc acaaatcatc tttagttgaa acaaaaatga ttattaacaa
    12421 taccgatgat aatttgataa ctgtatttct aataaccact ttcgaaaatt cttcaattcc
    12481 ttgaaaaaac caagaaatat ctaatgttag ccctacaata aatatcaatt gaattaagta
    12541 taaattttta tactttacat caaaaaaata aatataggct atatagagaa aggaaacact
    12601 caagcctatt aaaaattgaa taaagtaaat attccagaat tgtaaagata gtgctttttt
    12661 atctttcctt gatttagcga tatttcgaat acgaaaagga ttcattccca cagcaatgac
    12721 agtcattaaa aactgtgata ttgagaaaac atacccataa atccctaaac cagttgaacc
    12781 aattctacga ctaagtatag gtatagtaag taagggtaaa acaatcaaaa agacttgata
    12841 tatcgcatta taaaatatat cttttactgt ttttttcact ttatatccct ctctatcaac
    12901 tcaagaacct tttctgtact tgctcctgtt tcataatttc caatataatc aagtaactct
    12961 tgagaacttt tcaaaagctt ttcttgttgg tttttaaaaa catcaacaag gccataacta
    13021 tcttgtacgc ttataattgg taactcactt aactgtatat aaaaacctct ttctaagcta
    13081 tattcttttt catcatagtt aaaaagaata attggttttt ttgttagcgc aaaatcgaaa
    13141 aaaatagatg aataatctgt gattaaaaca tctatctctt caaaaagcat ttcaagagga
    13201 atcccatcat taattaaagt aatttgatgt tttttcatat attctatact tttagaatca
    13261 gttgctaatt tactatgaac attaggatga aatttagtca taaaatttaa ttcttgttgt
    13321 tgctttttaa aaaattcacg taagttatcc acacctaacc attctagttg cgtaattccg
    13381 ttgtcctcaa tattatttcg aaaagttgga gcaaataaga cattgatttg tttctttttc
    13441 aagtcaaaca cttgctcttt actagaggct aattcatcgt ttctaggagt tcctacttct
    13501 aatattttag aaggaacgat attgaatgct gaaacatact tcttagaact atagcgatta
    13561 ccagataata aatatgtaat tgactcacta tcttttttcg catagcttag gtaacgttta
    13621 ggtaacttat cttttgcatc aaattcaatt ttttttaaag gcgttccgtg ccatgtttga
    13681 aaataaagtt gttttttcct ttttgcatac ttaatcgttt tccgactatc gtctatccaa
    13741 tacttagctg tatataaata aaaggcagct aaaaaagaat cggagtcaat tcttttaata
    13801 taatctggta aatcagttat aatcgcttct tttttgatta accaaataat tctgtaattc
    13861 aatttttttt catgaatttt ctctgaaata actcttggat ttccagaata gttacgcccg
    13921 ccaaaacttg aaaata
//
LOCUS       DAXLPC010000068        13823 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.068, whole genome shotgun sequence.
ACCESSION   DAXLPC010000068 DAXLPC010000000
VERSION     DAXLPC010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.068"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            85..279
                     /locus_tag="ACF3UE_001984"
     CDS             85..279
                     /locus_tag="ACF3UE_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635366.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            548..847
                     /locus_tag="ACF3UE_001985"
     CDS             548..847
                     /locus_tag="ACF3UE_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635367.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(944..1378)
                     /locus_tag="ACF3UE_001986"
     CDS             complement(944..1378)
                     /locus_tag="ACF3UE_001986"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3635368.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1610..2320)
                     /locus_tag="ACF3UE_001987"
     CDS             complement(1610..2320)
                     /locus_tag="ACF3UE_001987"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFD3635369.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2310..3170)
                     /locus_tag="ACF3UE_001988"
     CDS             complement(2310..3170)
                     /locus_tag="ACF3UE_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFD3635370.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3175..3813)
                     /locus_tag="ACF3UE_001989"
     CDS             complement(3175..3813)
                     /locus_tag="ACF3UE_001989"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFD3635371.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3828..4127)
                     /locus_tag="ACF3UE_001990"
     CDS             complement(3828..4127)
                     /locus_tag="ACF3UE_001990"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3635372.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKEVTVIGIKNVMSAKEISEKFAETKWYQKNK"
     gene            complement(4170..5654)
                     /locus_tag="ACF3UE_001991"
     CDS             complement(4170..5654)
                     /locus_tag="ACF3UE_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFD3635373.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPEGYFLIVEDYDTYAEKQRV"
     gene            complement(5674..6135)
                     /locus_tag="ACF3UE_001992"
     CDS             complement(5674..6135)
                     /locus_tag="ACF3UE_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3635374.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGEDEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6153..7220)
                     /gene="ulaG"
                     /locus_tag="ACF3UE_001993"
     CDS             complement(6153..7220)
                     /gene="ulaG"
                     /locus_tag="ACF3UE_001993"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFD3635375.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADSKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7438..8208
                     /locus_tag="ACF3UE_001994"
     CDS             7438..8208
                     /locus_tag="ACF3UE_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3635376.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8481..9308)
                     /locus_tag="ACF3UE_001995"
     CDS             complement(8481..9308)
                     /locus_tag="ACF3UE_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635377.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9875..11110
                     /locus_tag="ACF3UE_001996"
     CDS             9875..11110
                     /locus_tag="ACF3UE_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3635378.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12109..12369)
                     /locus_tag="ACF3UE_001997"
     CDS             complement(12109..12369)
                     /locus_tag="ACF3UE_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFD3635379.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12396..13697)
                     /locus_tag="ACF3UE_001998"
     CDS             complement(12396..13697)
                     /locus_tag="ACF3UE_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3635380.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
BASE COUNT         4448 a         2828 c         2176 g         4371 t
ORIGIN      
        1 tatcataaag atatagatac ataatcattt tcacttacat atatttgaat attaactaaa
       61 aacagcaaga aagaagagga tcaaatgtat tatgtagaag taaaaacaaa aggcgtcaaa
      121 aacaaacaat atgtgaaagg tatcagtaac gaatatcctt tacttggttc atggaaagaa
      181 gctgctcctt tttccaaacc atgtgccata aaaataaaga acgagctaga aaaagaactg
      241 acttgtggca aagctgttgt agatatcatc gaaaagtaaa tccaatgtat agaaaggaag
      301 atcacacatg aaaagcgacg tacaaattgc taagattata gaattagaag aagaagacgc
      361 agtgttgaca attgaaaaaa aataaatgtt tgtataccat atgattattt caatatgtat
      421 cctggaattg gagatctcgt agagctatat caagatgaat caaatatact tgtcattcat
      481 catgaaatat agagacttat aaaattgttt atttttataa tgtatcagta tagaaaggaa
      541 ataaaacatg gattatactg ttgaatttga cagtgaacta cttaagcaat ttccacaaga
      601 agaacatttc atgtataaag aagcaatttc ccacaaagtg acagagtatt tggagcataa
      661 tttttttcgt ataaagccag tgcgtactcg ttcggcaaaa ggaatatacg agatgaaagt
      721 caaaattaat aaaaaaaatt atcgcatagc atttgcttta aaaaaaaatc atgtgttcat
      781 tttttatatt agttcgaatt tgcaaaaaat tgtatttgat aaagaggtga gtaaaaaaat
      841 aaaatagctg agcattggag gatagattga gtgatactaa gtctatcctc ttgtttttct
      901 aaagaactaa gctagaattt tttcttttgt acgttattat atgttatttg tcattaccaa
      961 aaagcacctt ttttcttcta gtatctatga cataagaaat accacccatt tcctttactt
     1021 gaacaaatcc tactgattca taaaattttt ttgttttctc agtatcatct gtcaataatt
     1081 cgatttggac tggtccataa ctagtgatct tctccaaagc ttcattcaaa agcactttgc
     1141 ctattccttg gcgctgatac ctcggatgaa tgaggatatc ttgaataaat gcgatcgtcg
     1201 caaaatcagt gatccaacga acgattccga taatcttccc ttccccatta cgctttatca
     1261 gagattcaga ttgttcaaat gctctagcta accttgcagt gtcttttgtg taattcgtcc
     1321 aaccaacgct cttatataat tcagaaatct catcgatcat aagggaatca atattcattt
     1381 ttttcttcct ttcttataca attctccctc taataataca gttctttgac tatttaatct
     1441 atcacatata actctcctgt aaagattctc tcgattcctt aaaatctctc tttcctttta
     1501 gaatgcatcc tttttgataa ataaaaaggt tgtgataaat tttcttcaca acctctgttt
     1561 ctctctatca agtgttatct tttaattttc tacccttacc ctagcatctc tattgcccgt
     1621 agtatgcata ctttccatgt ttgcgaaaat aatgtttatc tagtaaatat tgcgggattt
     1681 cacatatatt ggggttgatc agctcgtttt ctttggccat cagacaaatt tcatctaaga
     1741 tcaaactgtt ttctactgct ttcataggtg aatcccccca tgtgaacggt ccatgtccat
     1801 agacaagtac tccagggact tcgtttggat ctaattttct ttccttaaac gtctcgacaa
     1861 tcacattccc tgtatgaact tcgtaagctt ctcttacttc ttctttcgtt aattggcgtg
     1921 tacaaggaac cttaccataa aaagcatcag catgagtcgt gccataagct ggcaaatcgc
     1981 gtcctgcttg cgcccacatg acggagtgcg tggaatgagt atgagtaata gcagttatat
     2041 cttcaaaagt ttgatacaaa acaacatgtg tggggagatc tgaagatggt tttaagctat
     2101 cttcttctat tatatttccc gacaaatctg ttaccaccat ttgatctgct tgcatgcatt
     2161 catatctgac accgcttggc ttaatgacga tgactcctag ctcacggtcc acttcactca
     2221 cattgcccca agtcaatttg actaatccgt atcgcggcaa tgccagattt gcttcaagga
     2281 cacgttgctt cattgctgca attttttctt cacaagacat catagccagc ctccttcaat
     2341 ttagaactta agtagtcttt tgcctgctgg atttctcttc gaaagtcttg gcttttttca
     2401 ctccacattt caatcagaaa tgttccatca taatctagac gtttcaaatg tcttaataat
     2461 ccaagaaaat caacacaacc gctaccaaaa ggaacatcac gaaactggcc tgaatattct
     2521 tttgttacag ggtaagtatc ttttaagtgg atagcagtga tataatcgat ccctttctca
     2581 agttctcgag ccggattatt ttccggccat gcggacaaat tgcctaggtc tggatatact
     2641 tgtagaaaag gggaatgaat ctgttctttg atttctaaaa attttgaaat ggagttcata
     2701 aatggatcat ccatgatttc cacggaaaga atgatgccat atttagaagc ttcctttacg
     2761 ctttctttta ttccttcgat aaagtcttct ctggaattca ttgatttctc ttcataataa
     2821 acatcgtatc cagctatttg gattactttg acgcttagat tatgcgccaa atggattgct
     2881 tttttcatta gttgtttcgc tgcttttttc ttttctggat cagcagaacc aaacggaaat
     2941 cgccgatgcg cacttaaaca aatcgaatgg atacgtacac cggagctgaa catctcttct
     3001 ctcagctcag ctatcttttc ttcagaccaa tctaatcgtg ctaaccgctc atccgtctca
     3061 tcaatcgaca tctcgataaa atcgaagtcc atttctttta caagggaaaa acgttctttc
     3121 catgaaatat ctttgggtaa tgctttttca taaatcccaa tttgagccat ttccttaccc
     3181 ccagatacga atgatctcat ctttgaagtt ttgtgcggcc ttcatcggat catttgctgc
     3241 tgtaatacca cgaccagtga taaaggtata cacatcgatc ccttcaaata agtgtaatgt
     3301 gtgtggattt aatccaccag ttacagaaac attaaagcct agttcaatca gttttttgat
     3361 cttcgataaa tctttttcac cccaagtttc accagataac agcgcatcac ggctttgatg
     3421 gtagattacc tgccggatac cgatgttatg ccaatccatg gcttgttcaa aagtccaatt
     3481 gccgtagagt tctacttgca attcacctat ttctttttgt gctgcctcca tagttggaat
     3541 cgttgcacaa caaatgactg tcatccagtc tgctcctgct tttgcaacat tactcgccac
     3601 tgttcctcca gcgtctgcac atttcgtatc agcgactagt tttttatctg ggaacatact
     3661 gcgaatacag cgaatcgctt tttgtccttc ctgtaagcaa agaattgtgc ccacttcaat
     3721 aatatctact acatcaccaa ctttcataac atctcctaat gcatgttcta agtcattgtg
     3781 atctaacgca atttgcaaat tcggcctgct catcttagtt ccttccttta cttgtttttt
     3841 tggtaccact ttgtttcagc aaatttttca ctgatttctt tggctgacat cacatttttg
     3901 ataccgataa ctgtaacttc ttttttctct gcctgagtaa acatattcaa aaaattgact
     3961 ggcgtaaaaa ctacatcgta ttggccagct gaactttttc cctctgaaat ggcacaatga
     4021 tggattttgg taattggtac gtttagttct ttcattgctt tttccacact tctcatcatc
     4081 atcaagcttg ttcctgatcc atttgcacac gatactaaaa ttctcatctt aatccctcca
     4141 ttatgagtgt tgtctaatca gattttcttt tatactctct gcttttctgc atatgtgtca
     4201 tagtcttcta caatcaaaaa ataaccctca ggatttttcc gatattgtaa ctgcggaata
     4261 gccaataaac caatgacaac tacggcaatt ccagcataac ctaggacttt catgattact
     4321 gtaaacaatg gccaagctgt tgcccagtcg aacatcccga tataaccacc atatgttgac
     4381 atcccaatcc atgtagcgaa taatgctgaa ccgcctactt gtatgattcc tgaaagaaac
     4441 gggaacaggc aagcggcttt gaatccacct cggttattgg cataaactgc tataacggca
     4501 ttatcaaaga acaacggaat gaaaccggct atgacgatcg ttggtgattt caataaaatc
     4561 agtaaaccaa tcatcaaaaa ctgtcccaaa gcaccaaaca agaacccaat cgttaccgca
     4621 tttggcgaac caaagccaaa agtagcagct acgtcaattc ctggaacagc tcctggtaaa
     4681 attgtgtttg agattccttg gaaagattga gttagttcat cgacgaatgt ccgaacacct
     4741 aattgcaaga tcgccagata taccgcaaaa tttaaagaag tcgtcataat gtagaataag
     4801 aaactctgtc cttcttgcat gaattgcgct tgaatcaaat aatctttgcc tagtacaatc
     4861 agaatgatcc caaagaaaaa tagcatgagt aacgaagtag caaccatatt ctcattgaaa
     4921 atcgacaaga atcctggtaa tttgatatct tcgatttttt tgtcttgctt gattgatcta
     4981 tttttctttt catcccgctt tttcatccac tcagctaatt ttgcaaatat aaagattccg
     5041 aacatttgct gatgtgccac tgcaaatccg gcaccttctg tcaattcctg cgtgattcct
     5101 actgttaagt tagaagctac tgcccaataa caacctaaaa tcagtcccat aaaaatcaat
     5161 acttgtatcc tacctagatc aggaaagcaa aacagtaaaa tccaaaaagc ggtagctgct
     5221 tgttgaacct gaacgtttcc ggtagtgaaa acggaacgca gtttcgtata tttctgaaaa
     5281 cggactaata agatatttaa aacaaatgca atcagtaata aaatcatcac atctccaaag
     5341 gtacggccaa atgtctccat taatccagca tccacagcat tttgtccaaa ataaggatct
     5401 gtaaccatgg catccaaatt gaaccgttcc tttagtccaa ccaaaatcgg ccgaaaatta
     5461 ttgaccaaac caccagagcc aacagtcaaa ataaagtaac cgaccgttgc ctttaagaat
     5521 ccagcgatgc attcatgaag cgggcgtttc agcaaaatat agcctaataa cacgataaaa
     5581 ccaatcaggt atgctggctg cgtcaagata tttgttgcaa aatacgtcca aatgcttaac
     5641 aaaaattccc ccatcttttt tctcctctat caattaatta tattctgcca tcacaacttg
     5701 gtaatcatcg atggagttcg tagagatgag acgctcaacc aatccatctg tcattaataa
     5761 ttcggataat ttttggatat tttctagatg ttcttctgga tcttttgctg caagtgtaaa
     5821 aaacaaacta gccgttttct cctcatcctc cccttcactt tcaaaacgga ttggctgttt
     5881 caacttggta aatgaaatag ctgttccaaa aacaccatca cttttttctg aagaatgcgg
     5941 cattgctact tgaggtgcga tcacaatata aggaccgtat ttttctacac aatggatgat
     6001 ctcctccaca tacgtttcat caataatttc cttatcgatc aatacaagac agctttcggc
     6061 gatagcttca cgccaatccg tgatttcttt atctgggtaa tgaatcaatt gatggtcaaa
     6121 aaagtatttc agcaagaaac tccccttctt tcttataaaa acgacggaaa cggtgtatca
     6181 ttttcaatcg agaagacatc ttcaaatcct cgataaaaat taaactcaag atcatctttg
     6241 tttgtcggat agatgaattt cccgcctact tgccagatat aaggtttaaa tccatacttc
     6301 aggcgatcct ttttgaattt ccaaatttca gtgatctctt ttgaatcagc cataaaatta
     6361 gaccaaatat cgtagtggac aggaatcact acttttgcat tcaatgactc cgccatgcgc
     6421 agcatatcaa cagaagtaac tttgtctgtt atccctcgtg ggttttcacc ataggcccct
     6481 aaacagacat cgattttgtg ttcattacca tgtttggcaa ataaattgga gtaatgtgaa
     6541 tctcctgcat gataaagatt ccctcctgat gtttcgaata aatagtttac tgcaatttga
     6601 tccatctcct gaggcatttt tccttttaat acctcttctg gatcttcaca agtgaccaac
     6661 gctgtccgat caaacgcttc taaagctact acattgatgt ctttgatttt gactgcatca
     6721 cctggcttta ctgtaatcgt tttttcttca ggaattcccc atttttgcca cgtgcgaacc
     6781 acttcttttg gcccaatgaa tgttgcttca ggacaatttt gatgaactgc tgcggctgta
     6841 tggatatcta gatgatcgga atggatatgt gtaacgatta aagcgtctac attttttatc
     6901 gcaaaaggat cgattacgaa aggctgagta cgtaaattag gctgcatatt ttgaacgcca
     6961 ctcatacgca tcatctgatg gccttttttc atcatgccat tcccatgact acgttttccc
     7021 gtcccacacc atagatcaca taaaatattc gttccttcat gacttttcag ccaaattccc
     7081 gtacagccca gccaccacat agcaaaagtt ccaggatcca ctacttctgt ttcgatttct
     7141 tcattcaagt atgtgcccca ctcaggaaat gtttctacta accacttttc ttttgttact
     7201 tcattgacag ttttactcat ttgcttgctc cccccatatc gttgttccaa cttacaagta
     7261 aatattaatg tgtatcagca tccatggaaa cccttttata tgaccgtttg ttttttatat
     7321 gattttcttt cagtaatcaa tgattgtttc agtataataa agacagatat gaatgtttaa
     7381 atgaacaact agtcaaataa atccatggat caagatgtcc ctcaggaggc aaaagtcatg
     7441 aaaaactcac ttgtcaatat tgaaaaacgt caaaaagaaa ttttggaact gcttcagcag
     7501 actgaacaac tatcaacttt cgaattagct gaatcccttg atgtatctat tagtacgata
     7561 cgaagagatt taaatttatt agaagaaaaa aacgagatca tacgcaatta cggttattgt
     7621 tcttataatt acaaaaacca gactgatttt gatcaatctg gtcctgaaag gattaaacaa
     7681 gcgattgcca gagaagctag taaatacatt aacgattatg atacgctgtt tatcaattct
     7741 agctcgactg cgttgaaaac actggatttt cttcaatcta accatttgac agtcattaca
     7801 aacaacgtga aaatcaatta ctctccgcac aaagataatt gtagttatat tttaactggt
     7861 ggagagatgc gctttccaaa agaagcacta gtgggcgaca tcgcattaaa tacgatttct
     7921 tcagtcaatg cagacatttg tatcattggc tgtagcggag tcgatgtagt acatggggtc
     7981 acaacaaaga tattaaatga atcaacgatc aacgaaatga tggtcaacaa gacaatcaaa
     8041 tgtaagattt tagtcgctga tcatcgaaaa atcggactga catcaaagtt caagattgct
     8101 gatatttcag tctttgatta tttgatcact gataaatttt gttctgaaaa agtattagag
     8161 gagatcagaa atacggggat aaaaaccatt caagtagatt cattttaaga accaggacgt
     8221 aaatatgtaa ataggattat caaaaaaatg aataacaaat ttatcgataa atgaaaaaca
     8281 cgctacgctc aaattgataa aggaatccca agatgtgtcc atccaatcga taccatcata
     8341 atctattgct tcttttataa ccgttatatg ttgcctaaat aggaatcaaa caatatcgaa
     8401 aaaaggaggt atgacaaaag tcacacctcc ttttttcgaa taaacggtat tcaaatcaga
     8461 acactgattt cacaaccact ttatttcagg tcgttttcaa tcacctttac cgcgtaatca
     8521 tttccgttga aacgcgctat tttttttgcg tccatatatc tttctaaata atcatcttct
     8581 cctaattgct tatggcaaga agcaatttca taaagcaagt attccaatgc ataagtcgat
     8641 ttatgtttct tattatactc aatacccttc tcacataatt ggattgcttt atcataatcc
     8701 tcgattttac ggtaataggt ggcgatatca taatatacaa tgcagaccat cagattatca
     8761 aaatcagtct cactcaatat tttaagtgta cgctccacat aaactttcgc aaaatctaat
     8821 tctccttttg acaagtagat cattgccacg tttgcagctg cttgtaagtg atggatatct
     8881 gtttcggtcg tttgttccaa cacttgatta aaataaaata atgctgcatc tggttttttc
     8941 gcataaagat gatcaagcag tccttgataa aataaaattt gatttaaaag atcagaatta
     9001 cttacttttt cctgatcgat cgtttgtaaa attttataag attcttggta ttttgataca
     9061 gaattcaatg attgaatctc atttattttt ttcctgattt tgtcttcttc tgtttctact
     9121 aatatatcgg agatctcgac attcagcttt ttgcaaagcg cacttaagat attgatgcct
     9181 ggcgacatat tcttgttttc gatattgctg acagttgctt gttcacaaat gccttctgct
     9241 aattgtactt gtgttaaccc ctttttcttt cggtattctt ttagtaatgc tccatctact
     9301 ttaatcaaaa caatttcctt ccctttaaaa aattatttct cctttatatc atacacaaaa
     9361 aaaagttcta aacaaccaaa aatgtttaga acagaataaa aattttaatt ttaaaataat
     9421 attcaaatta aacaactggc gtatctgctc cttgatttct ttttgtgtta tctgaataat
     9481 tatcgtttac agttataaca catagtgaaa attgtcatgg cgagaaagtc taagaatatt
     9541 tttaaacata actatttctt tcttacgtgt gtataatgac gacagcacac ctatcaatta
     9601 atataattat tttatttttt atgttctcat gtttattttt aatgacacaa cttctcgtat
     9661 ttatctggca caacatataa atcgatcaaa aaattgttgc gtgttttttt gaaaattgga
     9721 gtttcaactt gattacaaaa tttaaattta gaagttgtga aaacagcgag agacagttta
     9781 atattcaaaa tatacatagg ctactcgaac gctgtgtttt ttagtatact agtaagaaac
     9841 gaagggatag actcattcca ataaggagga tttcatgaag acaattcttt ttgctcctgc
     9901 agtattcaat ttagctgaga caacacgaat gattgaggtt gccaaagcta tgaaagaccg
     9961 ttattactgt gtattctttg gcttttctaa aacttttgct cctttgatca cagaaagtgg
    10021 ctttgagtat catttactag cgccgatcct tacgaaaaaa caagaagaac aaatcataaa
    10081 atttgaccag ttgcgtacac ttaaaaaccc ttttaccaaa gaaatggttg cctctcgtat
    10141 cactagtgaa cagagtctga ttgctaagtt tgagcctcga ctgattgtga caggttcgaa
    10201 tgtgacaatt tttttatcgg cccgcaataa aaagattcct ttagtatatg ttaaacccta
    10261 tgctttgagt gaaccttttt ttcaatcaga gcatgcgctg atgccccacg agttacgttt
    10321 cttcggccct ttaagcaatc ccctttggca ctggacaaaa aagcgtatag taaatacccg
    10381 atggatcccc aatgccttca aacacgctgc acaaaaagaa atgcttcctt taccaaaaac
    10441 aagtttacaa atgatggatg ctgatctaaa tctcatcaca acgcctaaac tatttttgga
    10501 agaagaacag ctgccggaaa attatcgaat cgttggtcca atttttgcta agctcagtac
    10561 ttccttgcct gaagaagtgc taacttttat acagcgaaag caacaagaaa gaaaacgtat
    10621 tatctatttc gcaatgggta gttcaggcaa tccgcgtatg ttacgcaaaa ttttgttctt
    10681 cttacaaaaa caaccggatc tagcggttat tgcacctatt gactatctgc ttgatgacat
    10741 tcaatctgac tcagaagatc ttttaataac agaatatctg tctagtcatc ttttgcatga
    10801 attcattgat ttttctttta tccacggcgg ggaagggacc gtccaaactg cctgtgaatc
    10861 cggcaaaccg tttatcggtg tggggatgca atttgagcaa agctgtaata ttgactattg
    10921 tgtaaaatac ggaaacgcaa tcgccctcac aaaaccagtg actgaaagaa aactgcagat
    10981 tgctctgcgc gaagtttctt cacccaagat tcgtcagcag gcacgcacgc tgcaagccgt
    11041 ttttccaata aatggtccac aacaagcaat tcaagaaatc gaaaccttcc tgagcaacca
    11101 cccaatatag tttcaagtag aaaaagcttt tttaatagag actcatcagt aatttcgcta
    11161 ttcgagaccc agacagtgaa aatacaaaaa aagtaaatag tggattgaaa agttagagtt
    11221 acttaaatta cggtgtctaa aaaacacaaa atcatcctta aaataaaaga tctgacgcaa
    11281 tccaaatgag cataggtagc gtctgccatt tattcttagt caaattcttt gacacctttc
    11341 tctggttgga tcatctcaac gtttcttcaa aagaaagacc ataataatta ggcaaataca
    11401 ttttcttaaa atgtgtcata tagatctaga agcatcgctt tgtagagatt tgtgctgcta
    11461 gtcccttcaa caattactaa atcaaatgta ggatttacca ctttatcttt gataatcaac
    11521 ctccctcttc tgttgagaca atgatctcgc aatccgatgc atactcctat ataaactgcc
    11581 agcaatcccc acatgctgag tagatcatgt cagaatgttc tatgtcgtca gcaacgataa
    11641 actaaaagtc acgttcacca tgactgattg ctattcccag cgcaattatt tctatacacg
    11701 tttcatgatt tgaataaaca ctctcatcat acatattacc attcatacac catactgcag
    11761 cccctactat atggttgtaa gctcccaaat ctatatttgc cttgatcact ttggtagtag
    11821 atcgactaat tcttaatcca ttgctgataa aattttcatt tttgcctcct tctttctgcc
    11881 aaaacagtta aaacaataat aatctttatg taaaaaaggg ctgtgacaaa agccttgtca
    11941 cagtcccata ttccgaataa acggtggtca aaagcttgca tctgcggtaa taagttcaac
    12001 caaacgaaaa ataagccaac atttcacaaa aatttaagaa gcaattttcg taaatttctt
    12061 cttatttctt gaagctaacc acttctgtca caaccacttt tagaacattt aaagcttcga
    12121 tgtgacaaac catctatgct gctcgatcat aaaattgata gcaaaaattc cacaaagtac
    12181 atatgtcccc catgaaaaca aaacattcat atgcggtaca atgatctttg gaagaatcac
    12241 gatcaaaaat gatgccagtg cccaaatcca tcgattgatt tgaatatgat atgtagctag
    12301 catattcaat ataaggtgac tagccgttaa taaaaagata aaaacaaaaa ataaaatcag
    12361 ccaatacatt gtttcccacc ttctaaaaac caaacttaga cagtttggac ttcgttttct
    12421 ccacgacttt gttcatctga cagcatcttt ttatcataag cttttacaaa tggataatag
    12481 ataataaatg ctatcaatgt gttgatcatg atcaagataa caacacgcca gtcatttcct
    12541 gctgaaagat aaccgccgat tggagctggt aatgtccaag ttggcaaaac agtaaatcta
    12601 ttgaccattt ctaatttgac tgcaaaataa ctgataatag tcaaaactaa aggaactaag
    12661 ttgaacggga tgaacatgta aggattcaac atcataggag ctccaaaaat catgggctca
    12721 ttgatattga agataccagg aataatagaa aaacgaccaa cctctttcaa gaattttgat
    12781 ttacagaaga atataaacaa aacagatacc acgatcgttg ctcctgcacc accaattgtt
    12841 accgtccatt gataaaactg ttcaggagcg atatagggta attgggtggc agctgtacca
    12901 tctgccaatg cctttgcatt ctcatccaac atgatcagcc acattggacg aacaacagcc
    12961 cctacaatac tcatgccatg gataccaaat gaccacaaca aatggatcaa aaacattggt
    13021 agtaaaacac caagcaaatt attccctaaa atattggtta aaggctcgaa taacgataat
    13081 aaggtagcgt ttacatcaaa gcccgcgacg cttcgaatca gccaagtaat tgttaaaatg
    13141 actgcacctg gaatcaatgc ctcaaaacta cgggcaacag caggtggcac ttgttctggc
    13201 attttgatag taatatttcg atttttaaag aaacgatata cttccactgc aaaaatcata
    13261 gataagatcc ccgcaaacat cccagatgct cccaaagaac tcataggtaa gacccagcca
    13321 agaggtgcct tttcaggagt taaaacgttt acaggaactt gtaacataaa gaacgttcct
    13381 aaagataata taccacctgt cacactatct aatccatatg atttagctag atccgaaccc
    13441 ataacaaaag ttgcataaat agccatcaat cccatcgtca tcctaaaagg taaaacaatc
    13501 gttgccgaat aaggggcaat aaattcattc catccaggaa acggtaaatt gataaagacc
    13561 ataaaaaatg tcccaatcaa aatcaatgac aatgttgaaa caaccccatt acgaattgct
    13621 aataaatgac gctgtgtacc aatttttgcc attggtggga caagtttctc ttcgacccat
    13681 ttcatcagct tttccactaa aaccactcct tttcaataaa atatgaacca ttcattgcat
    13741 gacaacgcaa agaatgttca taactaatta tataattaag aaattttatt tcaatatatt
    13801 ctcttaaata atcaaattta ttt
//
LOCUS       DAXLPC010000069        13710 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.069, whole genome shotgun sequence.
ACCESSION   DAXLPC010000069 DAXLPC010000000
VERSION     DAXLPC010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13710
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.069"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            201..2672
                     /locus_tag="ACF3UE_001999"
     CDS             201..2672
                     /locus_tag="ACF3UE_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFD3635381.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(2775..4511)
                     /locus_tag="ACF3UE_002000"
     CDS             complement(2775..4511)
                     /locus_tag="ACF3UE_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3635382.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4508..5212)
                     /locus_tag="ACF3UE_002001"
     CDS             complement(4508..5212)
                     /locus_tag="ACF3UE_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3635383.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5343..5846
                     /locus_tag="ACF3UE_002002"
     CDS             5343..5846
                     /locus_tag="ACF3UE_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFD3635384.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            5806..6144
                     /locus_tag="ACF3UE_002003"
     CDS             5806..6144
                     /locus_tag="ACF3UE_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFD3635385.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6165..7583
                     /gene="ffh"
                     /locus_tag="ACF3UE_002004"
     CDS             6165..7583
                     /gene="ffh"
                     /locus_tag="ACF3UE_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFD3635386.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7695..8273
                     /locus_tag="ACF3UE_002005"
     CDS             7695..8273
                     /locus_tag="ACF3UE_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFD3635387.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8277..8798
                     /locus_tag="ACF3UE_002006"
     CDS             8277..8798
                     /locus_tag="ACF3UE_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFD3635388.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(8877..9431)
                     /locus_tag="ACF3UE_002007"
     CDS             complement(8877..9431)
                     /locus_tag="ACF3UE_002007"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFD3635389.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9684..9959
                     /gene="rpsP"
                     /locus_tag="ACF3UE_002008"
     CDS             9684..9959
                     /gene="rpsP"
                     /locus_tag="ACF3UE_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFD3635390.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            9971..10222
                     /locus_tag="ACF3UE_002009"
     CDS             9971..10222
                     /locus_tag="ACF3UE_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFD3635391.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10347..11138
                     /locus_tag="ACF3UE_002010"
     CDS             10347..11138
                     /locus_tag="ACF3UE_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635392.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11308..11829
                     /gene="rimM"
                     /locus_tag="ACF3UE_002011"
     CDS             11308..11829
                     /gene="rimM"
                     /locus_tag="ACF3UE_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFD3635393.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            11819..12580
                     /gene="trmD"
                     /locus_tag="ACF3UE_002012"
     CDS             11819..12580
                     /gene="trmD"
                     /locus_tag="ACF3UE_002012"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFD3635394.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12716..13063
                     /gene="rplS"
                     /locus_tag="ACF3UE_002013"
     CDS             12716..13063
                     /gene="rplS"
                     /locus_tag="ACF3UE_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFD3635395.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13423..>13710
                     /locus_tag="ACF3UE_002014"
     CDS             13423..>13710
                     /locus_tag="ACF3UE_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635396.1"
                     /translation="MGKDKRIVWKDQSDLKIILTISQFIETYEIKSSREYQKQLSKNP
                     HSAPSMWFIINKYGSWNNLLNSIGIDNNGSKKWARMETDELIKVAQIFIDSE"
BASE COUNT         4570 a         2482 c         2808 g         3850 t
ORIGIN      
        1 aaacgaagaa aaagtgttag tagaaaatcg ccttcgattt tccaccaaca caaaatatta
       61 tagaaccctt tttttttgct atatgacagg aatgaaaggt gtttgcaagc ttaatgtgag
      121 gaacactttc catatctgtt ctatactgga taggagaagt ttggaaatat ccagaaaacg
      181 aaatcaatcg aggtagccac atgaagaata aatggataaa tcgaagtaaa aaaaagaaag
      241 taacacaaag atcatcagat aaagtcatcc gtctttttcc atcgtataaa gaaggattaa
      301 cggcagatca agtcaaggaa cgaatagaaa aaggtgcagc aaataattca gtcgatccca
      361 cattcaaaac aaatcagcaa atcgtattgg aaaacatatt tacgtatttc aatttgatct
      421 ttcttatctt agccattttg ctttgtttag tagaatccta taagaacttg acttttttac
      481 cagttatcat agccaataca ggaatcgcca tttttcagga aattcgatcc aaaaagatct
      541 tggacgaact aaatgtttta aatacagcaa aagtcaatgt catacgagac gggatagaac
      601 aaacaataga tatagaagac cttgtaatag atgacattgt tattttagag actggatatc
      661 aaattccagc agatgcagag gtcgtggaag ggaaactgca agttaatgag gctttattga
      721 caggcgaagc agatgaaata accaaagaaa taggtgatcc attaatgtcc ggcagtttca
      781 ttgtttccgg aaaagcttac gcccgattag acaaagttgg agcagattcg tatatttccc
      841 agctgacagt caaagccaag acaatgggag aaggagaaca gtcggagatg attgcttctc
      901 ttaatcaatt gatcaaatgg attgggatca tcattattcc tatcggtatc ctgctttttt
      961 ctcaaagtta cttttttaat ggaaacacga tcaaagaaag tgtcgttgca atggaagcag
     1021 cattgatcgg tatgatacct gaaggactgt acttgctgac gacgattgca ttagcattaa
     1081 gtgcgactaa actagcaaag caaagagttc ttttacacaa tatgaaaagc attgagacat
     1141 tggcaagggt aaatgtcctt tgtgtagata aaacaggaac gatcacagaa aataaaatgt
     1201 ctgttcaaaa aatgatcgtc tctaaaaaac aagaaataat cagtcagtca gatcaattgg
     1261 aagcatgcat tgctgactat gcaaaagcga tggcaggaga caatgcaaca atggaagctg
     1321 ttaaagcata ttttacaaaa accactgatc aatcctatca ccatgttatt cctttttctt
     1381 ctgtccaaaa attcagcagt gtagcgttgg cagacaaggt gtatgtttta ggagcgcccg
     1441 aaatggtttt gcgcgatcaa ttgccggaat atgcggaaga gtttgtttct ttcgctgaaa
     1501 aaggctatcg cgtgttggtc tttggtgtgt acgatgggat tcttgaagaa ccagtattga
     1561 cagaagcagt cacaccatta ggctatattc tgattgctaa tcctatcaga aaagaagcaa
     1621 gagccacatt tgattacttc aaaaaacagc aagtagccat caaagtgatt tctggagata
     1681 atccgctcac cgtatccaat gtagctgtcc aagcagggat ttcacatgct gatcagtacg
     1741 ttgatgcatc taaattatca gaagaagaat atgaagcagc tgtcgaaaaa tatacagttt
     1801 ttggacgcgt caagccagaa caaaagaaaa tcttcgttca attgataaag cgtaacaata
     1861 cagtagctat gacaggtgat ggcgtgaatg atattctagc catgaaagaa gcagactgca
     1921 gtatagcgat ggcttccgga aatgaagccg ccatgcaggc ctcacaagtg gtcttacttg
     1981 attctgactt ttcacgcatg ccagaagttg ttgcagaagg acggcgcgtt gtgaacaata
     2041 ttgagcgatc agccagcttg tttttagtga agaatatttt ctcctttttg ctctcactgt
     2101 tttcagtgat ctttgctctg acctatcctt tagaaccatc acaaatcaca ttgattagtt
     2161 tgtttactat cggacttcca tctttcttgc ttgctctaga agaaaacaaa aagcgaatca
     2221 gagggaaatt catcatgaat gtgatggaaa aagctgtgcc aggtggacta acagatatga
     2281 tcgtagtcgg tgcgttggtg atctgcgggg tgactttgaa tctaaataaa acagatgttt
     2341 ctacagcatc taccatgctt ttgattgcag tagggttcct cgttctctat aaaatctgtt
     2401 caccgctgaa taaattcaga agtcagatca ttcttttctg tgctagcggt aacttttttt
     2461 cggtcatctt tttgcataag ctgttttcaa tcaccggtat ctcagctgta tcacttttgc
     2521 tgttgagcat tctatttttc tcggcagatt cgatttttag gcatttgacc acattggtag
     2581 aatatttgtt tgaacgtaaa aatgaaaaag agcaaaagcc gtttagtcgc gtagctaaaa
     2641 aatttctatc gatatttaaa cgagaaaatt gacgaaaagt atctcaaaaa agagtaaaaa
     2701 agaacaacca ctcgtgtatc tttcgaagca ggatgagtca tccaacttta aaacgcacga
     2761 gcagttgctc ttttttacat tttcggaatg gtaacggtga aagtcgaacc tgttccaaga
     2821 tgactgtcta cagtaatcgt accattaagg agttgcacgt agtcttttac aatcgctaac
     2881 cctaatccgg tcccgcctga atgtcggctt cgcgccttgt ctacgcggta aaaacgctca
     2941 aagatccgtt cctgatcctc aatgtcgata cctataccaa agtcttggac agaaaacgat
     3001 agatcatctg ttgcctgata gcggataata atctcgctgt cgctttttga atattggaca
     3061 gcattttcaa tcagattttt gataattgga taaaggatat ctgttttagt agtaaatggt
     3121 tcgttctttc caatcaatcg aatcgtcaac cgtttctttt cgatgattgg ctgataattt
     3181 tgaacgattt gctggaaata aggttctgta taaattgtct ggatctcgta agaattctcg
     3241 ccatcttttg acagctggat gatttcccga atcagtttat ctaaccggat cgcatctttt
     3301 tgcatgatct caagaaaaga agtcagagtt tgcgggtcat cttttgcacc atccagtaaa
     3361 gtctcggtaa aaccaatcag tgaagtcaca ggagttttta attcgtgaga gacgttgcca
     3421 acgaaatcct tttgtagctt ttctaaacgt cgcactttcg ttaagtcata cgccacccct
     3481 agaatctgtc cggtaccttc tgaattagta aagtagcgca aactcaagtc taatgtctgc
     3541 cgaccttctg taagggtgat ctcctgatgg atcagcggat gctcaggagt cacttgatga
     3601 atcagctgaa tgagttttgg ctcttgaatg acttctgtgt accgctgttc aggttgatag
     3661 cttaccacgt ttaaatgtag ctgcatcttt ggattaagca gtagtaaacg agaatcagca
     3721 tcatcaatca ggaatacgcc aatcatcagt tcgttcagta acgtatataa ttgctcttct
     3781 gtggtagtac acgcccgata catcttactc atttgttcgc tcaacgcatt aatcgtctga
     3841 tacaattctt cccattgatc gggtgtttgc atgattactt ccgcctgatt aggattttgc
     3901 accatttttt ttagtacggg cagcacggtt ttcaatggct ggtttttttg atagatcaga
     3961 taatagatca ttcctgcaag aacaaggaag aaagacagaa agaagaaaaa gacccaacgg
     4021 cgaaaactct cagttctcgg taaaaaaacg cttgtcggtt ctgcgatacg taaaatggct
     4081 tctaactggc cacttttttt gactggtaat gcgacatata aaagatcctc attcaaagta
     4141 gtacttttgc gcaaagcgct acctaggttc ccaccattca atacggcttt gatttcggga
     4201 cgggagtttc gctgttcatt caatgtttca ttgtttgtgt caaataagat ctttccagta
     4261 gcatccatta aagtaatccg ttcgttcgac tgatggacga attcttccaa agcagttttg
     4321 ttttgcgctg cttggaggtt ttcgacatct aattgccgga tcagcagttg tgcttttttt
     4381 gtcaggtagc tttcttgctg ttccacgatc tgctgttgaa aataatggga aatcaattgc
     4441 cagccaccaa aaaacaaact aactaaaaga ataagaaaga agagacgttc ataaattttt
     4501 ttccatttca tcgtttgggt tcctgaaact tatagccaaa tcctctaata gtcaccaagt
     4561 actttgggtg ttttggatct cgctcgattt tttctcgcaa atgactaacg tgtacatcta
     4621 cgattcggct ttgtcctgcg aagtcaaaat tccaaatgcg gtctagcaat gtgtctcggt
     4681 cgatcacacg gtcttttcgt ttcatgaaat aaacaagtaa ttcaaattct ttcggtgtta
     4741 gttcaatcag atggtcgtct acggtcactt gataattggt caaatcagca gtgatttgtc
     4801 caatcgatag atattcaggc tcagcttcat cttttgattg cttacgaggt tcaattcgtc
     4861 tgaatattgc tttcatacgg gctaatactt cgcgaggact aaatggtttg gtcaaatagt
     4921 cgtcagcacc tatttctagg ccaatgatcc gatccacttg gtcatcttta gccgtcagca
     4981 tcaaaatcgg tgtttcattt ttttcttgac gcagccgctg agtgatctcc atgccatcca
     5041 tcgttggaag catcacatct aaaatgatga aatcaaatga ttgttctaat gctaattcta
     5101 atccttcgcc tccatctgtg gcactggtta ccttgtagcc ttctttttcc aaattgaacg
     5161 tcaagagcgt tacaatagaa ggttcatcat caacaactag tatttttttc attcaaatct
     5221 cctttaaata ggtttcattc tgtttatatt ttagcataga atcagtacaa agggctattt
     5281 tacaaaagaa ataaatggta taataggaag gcactttgct gaatagaaag gaagagcagt
     5341 caatgattgg aatcagtgca tgtttaggcg gtctggcctg tcgctatgat ggacagaaaa
     5401 aagaagtacc agaattgatg gaactagttg aaactggaga agctgtcatg gtctgtccag
     5461 aagtgatcgg cggattacca attcctagag atcccgctga aatcattggt ggaaatggat
     5521 tcgatgtgtg gaaagatcaa gcaaaagtat ggacgacaag cggcgaagat gtaacggaag
     5581 cgtacaaaaa tggcgcgatc aaagcctatc aaaaattgca ggaaaaacac attgatctag
     5641 tcatcatgaa ggaaaaaagc ccttcatgcg gaacccattc gatttatgac ggaagttttt
     5701 ccggaataaa aaaaaatggt gccggagtgg ctactgctta ttttattcag caaaaaatga
     5761 ctgtgctctc tgatgaagaa tggctgaaaa ctagaggtga gcagaatgga aatcgaaaag
     5821 accaatcgaa tgaacgcgct ctttgaattt tattcgacct tattgacaga aaaacaaatg
     5881 aactacatgg aattatatta tgcagatgat ttttcattag gtgagatcgc ggaagaatac
     5941 gaagtaagcc gacaagcagt atatgacaat atcaagcgga caagcaagat cttggaggat
     6001 tatgaaaaaa aactccatct tttttctaat tatattgttc gagaacaggt attggaaaat
     6061 atgactgcat atattacaga taagtacccg gaagataaaa aactacttga atatgtacag
     6121 caaattcaag caatcgaaga ataaataaaa ggaatgaaga aaatatggca tttgaaagct
     6181 taactgaacg tctccagcag gcgatgggaa aaataagaaa aaaaggaaaa gtatcagaag
     6241 ctgacgtaaa agaaatgatg cgggaaatcc gccttgcctt actagaagcc gatgttaact
     6301 tgcaagtagt caaagatttt actaagcgcg tacgcgaacg tgcggtaggg gcagaagtgc
     6361 tggaaagttt atcacctgca caacaaatcg taaaaatcgt tgatgaagaa ttgacgatca
     6421 cacttggttc tgaaacagca gagttaaata aatcaccaaa aataccaact gttatcatga
     6481 tggctggtct tcaaggggca ggtaaaacga cctttactgg taaattagcc aattatttaa
     6541 agaaaaatga aaatgctcgt ccgctcctaa tcgcagggga cgtatatcga ccagctgcga
     6601 tcgaccaatt gaaagtatta ggtcaacagc tagacgttcc tgtatttgat atgggaactg
     6661 aagtcagccc ggtagagatc gtccgtcaag ggatggagtt agcaaaagaa aagaaaaacg
     6721 actatgtatt gatcgatacg gcaggacgtc tgcatatcga tgaaacattg atggatgagt
     6781 tgaaacaaat caaagaattg acgcaaccaa atgagatttt gcttgttgtc gatgccatga
     6841 ctggtcaaga tgccgtcaac gtagctgata gcttcaacca gcaattaggt attacagggg
     6901 tcgtcatcac taaacttgat ggggatactc gaggcggggc agcactatcg atccgctcag
     6961 tgacaggcgc accaatcaaa ttcatcggtt ctggtgaaaa attgactgac ttagaagtat
     7021 tccacccaga tcgtatggct agccgtatcc ttggtatggg ggatatgctg acattgattg
     7081 aaaaagcgca gcaagactac gacgagaaaa aagcggaaga acttgcacag aaaatgcggg
     7141 aaaattcatt cgatttcaat gactttattg aacagcttga tcaagtgatg ggtatgggcc
     7201 cactggaaga tctaatcaaa atgatcccag gaatgaatca agtccctgga atcgaaaacg
     7261 tcaaggtaga tccaaaagat gttgaacgca aaaaagcgat ggtttattct atgacgccag
     7321 cagaaagagc aaatcctgat ctgttgaacc caagccgtcg tcgccgaatt gctgccggtt
     7381 ctggaaacag tgttgttgaa gtgaatcgaa tgatcaaaca attcaaggaa tcaagaaaaa
     7441 tgatgcagca aatgtccaaa ggggatatga acatcccagg tatggaccaa atgtttggtt
     7501 caggcgtcaa aggaaaacta ggcaaaatgg cgatgaatcg aatgatcaag aaaaataaga
     7561 agaaaaagaa aaaacggaaa taagatgaaa aaaacagctt cggtacagac tgaaaatgtc
     7621 tactgccgga gcttttctat cagcaatttt tattctttac taatacaatt actctaaacg
     7681 aagaggtggc acagatgaga tgtccgtgga gtgaacaaac agaaagtatg cggcaatatc
     7741 atgatactgt ctggggtgtt cctgaatatg atgaccaaaa gctgttccga aaattgatgc
     7801 ttgatattaa tcaagccgga ttgagctggc agacgatttt aaataaaagt gaagcattcg
     7861 atgaagcata tgatcgattc gatatcaaaa aagtcgcaaa ttatggagaa acaaaaatca
     7921 gtgaactaat ggaaaacaaa ggaattattc gtaaccgaag aaaaatcgaa gcagccgtcc
     7981 aaaacgccaa agcagtcttg aaaattcaag aagaaatcgg cagtttttca gagtatcttt
     8041 ggtcgttttc taatggaaaa atcgttgatt cttcttatca ttcacaagaa gaagtcccaa
     8101 caacaagtcc tctttcagat gaattagcaa aagatctaaa gaaaagagga tttaaattta
     8161 tcggaagcac aacaatctat gcttttttag aagctgtcgg gatcatcaat gatcaccttg
     8221 acagttgttt ccgcaaagaa gaggtcgtac gtatcggcag aaagggcgaa taaagcatgc
     8281 gaaaaatcat attttatggt gctataagtt tagatggcta tttggcaacg aaaacggatg
     8341 atcttcaatg gctttttgac actccaacag gtaagcaaac tacttatgaa gctttttatg
     8401 aaacaatcga tacgaccatc atgggcagaa aaacttatca ggaagcaaaa aaatatttgg
     8461 agaccgaagc aatttatcca gagaaaaaga atttcgtttt ttccacccac gcacaattac
     8521 aattgccaga tgctgaggtc gtaaacgaag atcctgttgc ttttctaaaa aatctacaaa
     8581 tgacagaagg aaaagatatc tgggttgtgg gtggcggtcg attgatcaaa ccgctattgg
     8641 aacatcaaat gattgatgaa tggtatatcc agattacccc tgtattatta ggggacggga
     8701 ttcctttatt ccaaaaagga acatatgaag cgcgttttga aatgctagac acgacacgat
     8761 tcggtgaatt tatcgaattg cattatgtac gaaagtagaa gtaaataaaa taaaaaaggc
     8821 aactatatgc agaaatgtcc tgtacatagt tgcctttttt attaccgtta tgctttttac
     8881 tctgttaatt tgttagaaaa atctagatac gcatctaaaa tcgtttggaa gaaacttaat
     8941 gttccttcaa cgatattacc attttcatca attagattcg caacgtttcc gatatatgct
     9001 tccggttgct gcaaggttgg cacattcaaa aagacaagtg attggcgtag atggtggttt
     9061 gcgccaaagc cgccgatccc acctggtgat gcagtaacga ctaaacctgg tttatgatcc
     9121 caaacactgt gtccataagg tcttgagcct acatctaaag catttttcaa tactgctggc
     9181 acagaacggt tgtattcagg agtaacgaaa acgacaccgt ctagtcccct cacttcctca
     9241 cgaaaacgag tccattcagc aggagcctgt tctggagttt cgagatcctc attgtaaaat
     9301 ggcagatcat cgatttttac aaatacactt tcgtaccctt caggaagcaa tttcgcaaaa
     9361 gcttctgcta cttttttgtt gtaagaatct tttcttaaac taccaataaa aaatccaatt
     9421 ttttttgtca tacgattttt cctccttcaa actatctata ataatcttac aaaagataag
     9481 taactggagc aaataaaaac acttactgac aaaagctaca tagaagatag attacttatt
     9541 tttaacaaaa aagaagtcta aaatcttcta ttttctaaaa aaaatcgaat ttaatcaagc
     9601 tgtaaagaaa aaaagcttta cagggtaaaa aaaaactgtt acactacatc ttgtgaataa
     9661 aacaatggag gtggaaataa ataatggcag ttaaaatccg tttaaaacgt atgggttcta
     9721 aaaagagtcc gttttaccgt atcgtcgtag ctgattcacg ttctcctcgt gatggacgtt
     9781 tcatcgaaac tgtaggtact tacaatcctt tgaaagaccc tgcagaagta gttttaaaag
     9841 aagacttagt tcttgactgg ttatcaaaag gtgcacaacc ttctgacact gtacgtaaca
     9901 tcctttcaaa agaaggcgtt atgcaaaaac accacgaagc taaattctca aagaaataag
     9961 gtgaccggat atgaaagatt taagcgactt agtcttaaca atcgttcgtc cgctagtcac
    10021 ttatcctgat caagtcaagt tagacgtcgt agagtcgaaa gacttttacg agtacaatct
    10081 aacagtggct cctgaagata ttggccgtat cattggaaaa caagggcgtg ttgctaaagc
    10141 aatccgcaca atcgtttacg gtgttcggat caatgcaccg aaaaaagtgc gtttgaatat
    10201 catcgatgat aaggaaaagt aaataaacgt gctgtactcg aattttcgag tgcagctttt
    10261 ttgttttttt tattaattga agaaatgatt atttggcaaa acaagcaaga aagcgtatcc
    10321 ttataggagg agggagtgaa cagccaatga gaaagaaaat gttatttatt ccatttgctc
    10381 tattgttaag cgcttgtagt tcggttactc aagaatcaga caatacacat ctatcaagca
    10441 gtatatctga aactgttacc agtccagaaa aaagtagtac caaaacggct tccaccactg
    10501 aacaaacaat ggctacctca aataatgaga aaaagactgc tttagaccag ttgaaagaac
    10561 aacagccaaa tgttcccatg cctctagatg taccagtctc ttcaggctat ctcaatatcg
    10621 cagcgacaca tacaaagcaa ggttattcta ttttatatta cagaacagat cgtcccctcg
    10681 ggttgaatgc tgacgaattg aatcaagaaa cgcctattgc aacctatcta tatcaatatg
    10741 ggtttgcttc tagtcaagaa acaatccaag ttttgcagcc atttgagatc gacacaaatg
    10801 gtcagcaagt ggacttaggt tctcgaatca cagggtatca gcaaggtgca gcaggttcaa
    10861 gttttcttga atggcaagaa ggaaactggc gtattcgaat ccgtgggaat aatatagaag
    10921 gccaagatcc cttactatta gctaaagaaa tcgtagctta tttggaagaa aacagtctac
    10981 cagcacctga acaatttggt aaaattactg ttgatatggg tgatacgacg aatcgagccg
    11041 tagaagtaag ctggcaagaa ccgaaaaatg cctatacgat cactcatcaa gatcctatgt
    11101 ctgcgttgaa gatggcagtt tctatgaaga ggttgtgaaa tcagcgcgct gatctgagcc
    11161 catcatttaa ctccaagtca caggaagtaa tcaaaaatag cacgccgcat ttttgcataa
    11221 ttttggctta ataccttaaa agaaaactag aattgcctct tcacacatgc taaaataaaa
    11281 cagacaaaaa agaaatgggg atataagttg actgaatact tgaatgtagg aaaaatcgta
    11341 aacacacaag gtatcaaagg cgaagtccgt gttatctcaa caacggattt cccagaagaa
    11401 cgttacaaaa aaggaacggt gctaacacta ttccaagacg gaaaagcacc tgtggaatta
    11461 acagtcaaaa gtcatcgcaa acataaaaat tttgacttat tgagttttga aggacatcct
    11521 tctatcaatg atgtggaaaa atatcgggat ggcatattaa aagtgtcaaa agacaactct
    11581 gtagatctag ctgaaaatga attctattac catgagatca tcggtctgca tgtattagaa
    11641 gatggaactg agttaggtaa agtaaaagaa atcttgtcac caggtgccaa tgatgtttgg
    11701 gtcgttcaac gtccgaaaaa agctgatata ttgcttccat atatcgcttc tgtcgtcaaa
    11761 gaagtcgatt tagaagctgg agtggtccgt gtagaaattc cagaaggact gattgacgat
    11821 gaagattgat gtattgactt tatttccaag aatgtttgaa ggtcctatgg gggaatccat
    11881 catcggtaag gctgtagata aaggattatt agatatcaat atctctaact tccgcgatta
    11941 ttcagataac aaacatcaga cagtagatga ttatccatac ggcggtggag caggtatgct
    12001 gctcaaagtc cagcccatct atgataacat ccaagccatt gaaaaagctg caccggatgt
    12061 caaaaaaaga gtaattcttc ttgacccagc tggtaaacga ttcgatcaga aaatggcaga
    12121 agaattttca caagaagaac acttagtatt catttgtggt cattatgagg gatatgatga
    12181 acgtatccgc acattagtga cagatgaagt ttccttagga gattatgtcc ttactggggg
    12241 agaattaggt gcgatggtca tgatcgatgc aacagttcgg cttttgccag atgtgttagg
    12301 gaatcagact tcagctcaaa cggattctta ttcaaccggt ttattggaac atccccaata
    12361 tactcgcccg gcagaatata aagggatgaa agtaccagaa gtattgacaa atggaaatca
    12421 taaattgatt gaagaatggc aattaaaaga atcactaaga aggacctatc aacgtcggcc
    12481 tgatcttttg gaaacacttg aatggacacc tcaaatgacg aaatttttag aagaaatcaa
    12541 gaaagaagaa caagaaaaaa cagcagatga agccaagtga ctttttctaa aatcttcttt
    12601 acagtaggtt gataatatgt tagtatttta tggtgagtgc aaaagcactt aactattacg
    12661 atattccgct gtgagaaaag ctcataagaa tatttggaat aaggagaaga aaaccatgaa
    12721 tccattaatc gaagaattaa caaaagaaca attacgttct gacatcccag cgttccgccc
    12781 tggtgacact gtgcgtgttc acgcaaaagt tgttgaaggt actcgtgaac gtatccagtt
    12841 atttgaaggt gttgttatca aacgccgcgg tgctggaatc agcgaaactt atacagtacg
    12901 taaagtttct aacggagtgg gcgttgaacg tacattccca ttgcatacac cacgtgttgc
    12961 aaaaatcgaa gtagttcgct acggtaaagt acgtcgtgca aaattgtact acctacgtgc
    13021 attacacgga aaagctgctc gtatcaaaga aatcagaaga taaacacgga aaacttcctt
    13081 ggaaatctga aatctgtgaa aagtccttgt atatcaagga ctttttcttt tttctctatc
    13141 acatttttaa tatgttttgg gccttttttt ctaatgttct ctcaaattgt cctgaatctc
    13201 ccaatattga ctactattat cgtcaaaata ccgaaaaaat tagtagtcat tttgacgaca
    13261 aatttaatac gaaaaatacc taaacactta ccgaatttag caatttttga acccgagttg
    13321 ctaaaaaggt tgaatgcttt cgaaaaaagc aaaacatata ccattgtgct aaaaagttta
    13381 tgtgataggt ttctatttaa ataattttag gagttttttg taatgggaaa agataagcgt
    13441 attgtttgga aggatcaaag cgatttaaaa attatattaa caattagtca gtttattgaa
    13501 acttacgaaa taaaatctag tcgagaatat cagaaacagt tatcgaaaaa tccacattca
    13561 gctcccagca tgtggtttat tattaataaa tatggctcgt ggaataattt gctgaatagc
    13621 attggaattg ataataacgg atctaaaaaa tgggctagaa tggagaccga tgaattaata
    13681 aaagtggcac aaatatttat tgattcagaa
//
LOCUS       DAXLPC010000070        13428 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.070, whole genome shotgun sequence.
ACCESSION   DAXLPC010000070 DAXLPC010000000
VERSION     DAXLPC010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13428
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.070"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..306
                     /locus_tag="ACF3UE_002015"
     CDS             <1..306
                     /locus_tag="ACF3UE_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3635397.1"
                     /translation="HFARREKKLYRSLYLEEYGGGKEMQNFSYTYFVNTVKRDPAYVN
                     LSEEQIESLYNGTWIIATGIAALMSSSIIHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(484..924)
                     /locus_tag="ACF3UE_002016"
     CDS             complement(484..924)
                     /locus_tag="ACF3UE_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFD3635398.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLSGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            1082..1846
                     /gene="map"
                     /locus_tag="ACF3UE_002017"
     CDS             1082..1846
                     /gene="map"
                     /locus_tag="ACF3UE_002017"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFD3635399.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            1878..2801
                     /locus_tag="ACF3UE_002018"
     CDS             1878..2801
                     /locus_tag="ACF3UE_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFD3635400.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            2877..4016
                     /locus_tag="ACF3UE_002019"
     CDS             2877..4016
                     /locus_tag="ACF3UE_002019"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFD3635401.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            4009..4809
                     /locus_tag="ACF3UE_002020"
     CDS             4009..4809
                     /locus_tag="ACF3UE_002020"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3635402.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            4809..5636
                     /locus_tag="ACF3UE_002021"
     CDS             4809..5636
                     /locus_tag="ACF3UE_002021"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3635403.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            5641..6348
                     /locus_tag="ACF3UE_002022"
     CDS             5641..6348
                     /locus_tag="ACF3UE_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3635404.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            6448..7314
                     /gene="rfbA"
                     /locus_tag="ACF3UE_002023"
     CDS             6448..7314
                     /gene="rfbA"
                     /locus_tag="ACF3UE_002023"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFD3635405.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            7328..7900
                     /gene="rfbC"
                     /locus_tag="ACF3UE_002024"
     CDS             7328..7900
                     /gene="rfbC"
                     /locus_tag="ACF3UE_002024"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFD3635406.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            7922..8950
                     /gene="rfbB"
                     /locus_tag="ACF3UE_002025"
     CDS             7922..8950
                     /gene="rfbB"
                     /locus_tag="ACF3UE_002025"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFD3635407.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            9048..9899
                     /gene="rfbD"
                     /locus_tag="ACF3UE_002026"
     CDS             9048..9899
                     /gene="rfbD"
                     /locus_tag="ACF3UE_002026"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFD3635408.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            9933..11966
                     /locus_tag="ACF3UE_002027"
     CDS             9933..11966
                     /locus_tag="ACF3UE_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635409.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPAKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKIDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKEIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            12010..13290
                     /locus_tag="ACF3UE_002028"
     CDS             12010..13290
                     /locus_tag="ACF3UE_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFD3635410.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVCTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIATLLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
BASE COUNT         4120 a         2269 c         2844 g         4195 t
ORIGIN      
        1 cattttgcaa gaagagagaa gaagttgtat cgttcactgt acttagaaga atatggtgga
       61 ggaaaagaga tgcagaattt ctcttatact tactttgtga atacagtgaa acgcgatcca
      121 gcttatgtga atctttcaga agagcagatc gaatctttgt ataatgggac atggatcata
      181 gctactggga tcgcagcttt gatgtcttca agcatcatcc atccaactga tgaacagatt
      241 gaaaagatga tacaagacag tatagatgct atcttgaaat tcaaagaacc aatagaaatc
      301 gattgaatat actcaaaagt tccacaaatc agtagataac aagagatgtg tcaaaataag
      361 gaaaagttcg tttttcttac agcgtatgca tttttaactc ccgaagaact cttccatgaa
      421 tgcaatgaat aaaagagccg tacagattga ataaatctgg atggctcttt tattgcaagt
      481 atattaaatt tttgcgacta gttctttagc gaaagcttct aaattttcga tatcttcttc
      541 ttcagcattc agatccactt taacattttc ggctcctttt gatgcgcctg tttttgcaaa
      601 agcagcatcg aaatcatcca ccgatttgca gaattcatcg taaaaagtat caccagatcc
      661 gcagacaccg taaatttttc ccgatagatc caattcttgc aagtcttcat aaaagtctac
      721 gatctcatca ggcagatcgc catcatcgta tgtataagta gctactacgc aaatatctgc
      781 ctcctcgaat tcatctgcat ctacttgggt acattcgttg atttcgactt cgatatccag
      841 attttcaaat gcttctgcaa caatatcggc gatttcttca gtgtttcctg tcatgctagc
      901 atatacgatt tttgctaaag ccatgatgtg cctcctcgtt tataattatt taacaattat
      961 gaattatacc aaaacatcat tgaaaagaaa ataaaaccta gagacacctg gggaatgtca
     1021 tttggctaaa tgtatgccgc tatgttaaaa tgagagggat ttgtaaaaag gagacgaaaa
     1081 tatgattact ttaaaatcag cacgtgaaat tgaaatgatg gcagaatctg gagctttatt
     1141 agcagatgta cataaaaatc tgcgtgattt tataaaacca ggaatcacaa gttgggatat
     1201 tgaggtattt gtcagaaact atatcgagag tcatggcgga attgctgcgc aaattggctt
     1261 tgaagggtat gaatatgcga cttgtatcag tataaatgat gaaatttgtc atggattccc
     1321 tcgtaaaaag cctttgaaaa acggtgattt ggtaaaagtc gatatgtgta tcgatttgaa
     1381 aggcggcatt tctgattctt gttgggccta tgtagttgga gaatctacac ctgagatcga
     1441 ccgattgatg gaagtaacga agaaagcttt gtacatcggt attgagcaag cacaagtagg
     1501 gaatcggatt ggtgacatcg gtcatgctat ccaaacttat gtagaaggcg aaaatctagc
     1561 gatcgttcgt gattttattg gtcatggcgt tggtcctacg attcatgaag aaccagcagt
     1621 tcctcattac ggagaagctg gaaaagggtt gcggttgaaa gaaggcatgg ttatcacgat
     1681 cgaacctatg gttaataccg gaacttggaa aatgaaaatg gatcctaacg gctggactgc
     1741 gtatacaaga gacggcggac tttcttgcca atatgaacat acattggcta ttactaaaga
     1801 tggtccaaga attttgacat cacaaggaga agaaggcact tattgatcta tccagtcaat
     1861 aggtacggga gaggtacatg aaagtttgga acaaaataaa acaaaatgaa aatctgatgc
     1921 gctttattga gacgactcaa aagcgcatca ctgattcaga aatgagtacg acctctgtcg
     1981 tcgttgctta ttatttactc ttgtctttat ttccattgat tattgctttt ggtaatattt
     2041 taccgtttct ccacatcgat caagagactg tactgaccta tttacgagaa gtgattcctg
     2101 agaccgttta ccagtttatc ggtcctgcaa tcaaagacct tttgacacaa agttcaggag
     2161 gcttgttatc cgtttctgca ttagcggctt tatggtctgc aagtcaaagt atcaatgctt
     2221 tgcaaattgc gatgaataaa gcgtatggcg tagaaaatag aaaaaatttt ttgatcgtcc
     2281 gtttcttctc actaattgtc attgtcttgt tcatgattgc tattagtggg gtaactatcg
     2341 ttcttgggtt gggacagctg attttggatg ctattcagcc aatcgtacaa atacccgtga
     2401 actttatcga tcagttccaa actttgaagt ggccaatcac attggtagct ttatttgtca
     2461 tcatgttctt gatttattta attgtcccta atgctcagtt gaagttgaag acgatcattc
     2521 cgggcacgat cttcgctact gtcggctgga tgctgttatc acaagtgttt agtatctatg
     2581 ctaggtattt tgcaacgagg atcagcggtt atcagatcat aggaagtttt attgtactca
     2641 tgctttggct taattttgct gctacgatca tcattttggg cggaatcatc aatgcagttg
     2701 ttcaagaata cgtgacgggt catcaaatca aaaaacgtcg agatccaagc cgaaaatggt
     2761 tcaataaatt gaaaactaaa ttttctcata aaaaaaagta gaaacaagag ttcttattgt
     2821 aaatttatat cagtaattta taataattat gactcttaat taaagtaggt gcccatatgc
     2881 ttgtttcttt tagtatggtt ataagatttt ttctgacaat tttattatca ctgatattaa
     2941 cacctgtatt caaaatcatt tcagtacaaa caggtatggt cgacaaacca aatgaaagaa
     3001 gaataaataa agttccaatg ccttcagcgg gcggactgcc tatctttatt tcatttgtta
     3061 tatcgacttt attcttattc cgtaaaatta tccctcaatc gtatattgta ccgatcttga
     3121 ttgcttcttt agtaatcata gtcacaggag tgctcgatga taaatatgag ctgacaccta
     3181 aacaaaaaag tatagggatc ttgattgctt ctcttattat ttattttgta gcagatatac
     3241 gtattgattc cttcacgctt ccttttattg gatatatcca actaggctgg cttagttttc
     3301 ccgtaacgat tttttggatc ttcggtatca cgaatgcggt caatctgatt gacggtttgg
     3361 atgggctggc ggcagggatt tcattgatcg gtttaattac gataggaatc attggatatt
     3421 ttttcctcca tgcttctaca gtgtatattc cagttgttat tttctgtctt gtagcaagta
     3481 ttatcggttt ttttccttac aatttttatc cggcaaagat ttatttaggc gatacaggag
     3541 ctctattcct agggtttatg atggccgtcc tttcactaca agggctgaag aacgtgactt
     3601 ttgtttcatc gatttctttg ctgatcgtca tgggagtgcc ggtaacagac acgttttttg
     3661 ctatcattag gagaaaagca aaccgtgttt ctttttctac agcagataaa aaacatcttc
     3721 atcaccgact aatcagttta ggctttactc ataaaggtgc tgtcctgacg atttatgcga
     3781 tggctttgat gttttctttc acagctatgg tcatgaatta tactggaaga atcggaacga
     3841 tcatattgat tattgccatg ttgtttgctg caattttatt atttgaattg attggtctga
     3901 tcaatgagaa acatcagttt attttaaaaa cattgcgatt tttagggaat aaagagtacc
     3961 gtacgcaagt aaaacagaaa tatttgaaga aatggaaccg tcatatagat gaataacaaa
     4021 ttaaaccagc cgatccttat tagtattgtg acggcaaaca gtgataaaat ttttcggaca
     4081 ctagataatt ttatttcaac tgtaaaagat gaaacagcag taaaaatccg aatttttgac
     4141 aacaattcac ttcccgagta caaaaaaaga ctaacagagt ataggaaata tccctacatc
     4201 gatatctatt ttcatgatga aaattccgga tttggttatg gacataatca caatctgata
     4261 gctagcgatt ctcgctatgg cattatttgt aacccagata ttttagtgga tgaagagaca
     4321 gttacagcat tggtcttgtt attgaaagaa catccggaat gtgcgatgtt agcacctaag
     4381 attcttaatg aagatggaac aactcagcac ctcatccgtg agcagctggc tgtttttgat
     4441 tacgttttgc gctttgtgcc tttcaaatgg gtcaaaaaaa agtttgacaa acgactggct
     4501 gtgtttgaat gccgaggatt gcctactgat gctaatagtt atgtacggat gatctcaggt
     4561 agttttatgg tagctgatat tgataaattt aaagagataa aggggtttga tgagcgtttc
     4621 ttcatgtact ttgaagacaa cgacttgtgt ttgagttttg aaaaagcagg ttacaagtta
     4681 ttgtacacac ccttttatgc agttatccat ttttacggga agggtgcgca tcgaaatgca
     4741 aaactgtttc gcgtgttttt gacttctatg atgaaatttt tcaataagtg ggggtggcgt
     4801 tttttctgat gaaaccagaa atattagtag tcgttgtgct ttatcagcaa ctattcagtc
     4861 aatctccagc ttatggacca ttaagcaaag cacttagcga aaagcaaatt cagcttatta
     4921 tttacgataa tagtcctcaa aggcagcaaa atgagctgtt tgaaaaagaa aatatcgttt
     4981 atcatcatga tccgcaaaat cctggtttag cggtggctta taattttgcg ttgtctcaag
     5041 cagatgaagg aacacgttgt ctcgtcactc tggatcagga tacgaggcta gtcgacgatt
     5101 attttgaact attgcgtaaa gtaaccttta cagatgaatg tgttgctgca gttccgatga
     5161 ttttttctgg gagccgacaa gtttctcccc tatattcaga tcgttatatc aatcgtacag
     5221 ctcaagcagt agaagttgaa ggcccaacag ctgaacgaat catggcaatc aattcaggtg
     5281 ttgcctggtc tgtcaaattt ctaaaaaaga ttggcgggtt taatcctgct ttttctttag
     5341 attttttgga tcattggctg ttttggaaag tggatcagtt ggaaaaaact gtggagatcc
     5401 ttcctgtacg aatggaacat gatctttcgg ttttagacta tgaaaaagtt tcaagtaatc
     5461 gataccgttc tattttacaa gcagaaaatc gattttatca tgaatatgat caaaggcatt
     5521 tatccagtca ccgacgacaa ttattgttaa gaacagctaa acagttcttg accgtcaaaa
     5581 accggcatat ctggcggatg actttgcgct catatgttaa gaattggaag gtgtgaattc
     5641 gtgcgttcgg tttgtatagc tacctttaat ggaggcagat atttaagaga gcagttagat
     5701 agtattttat ctcagctttc agcagaagat gaagtagtca tttctgatga tgggtcagta
     5761 gatgatacat gggatatatt aactgaatac gcagaaaaag ataagcgaat ccagcttttt
     5821 tcggggcctc gtcaaggatt gatcgctaat tttggttatg cgatccagca gacgaaagga
     5881 gatctaatct ttttggcaga ccaagatgat gtttggttgg agacaaaagt gaaaaagatc
     5941 actgactatt ttgagcagaa tccggatcag ctagtagtag tttctgattt aatcattgtg
     6001 gacagcgagc tgcaagagat ccatgattcg tatttttcgt ttcgaaattc caaagaagga
     6061 tggcttaata atgtgataag aagtcactat attggtgctg gtatggcttt ccggtcttct
     6121 ttaaaacccg atattttgcc gatcccgtca gaagtgccga tgcatgatat gtggattggt
     6181 ttgctgggag gaaagaagac tgggttccta agagaaccgt taactctgta ccgaagacat
     6241 gatttaaacg cgagtgagat tgaaacacat tctaaattac ggcaaaaaat ttcttggcgt
     6301 gttcatctga ttacggcgtt gatcaaacga aaatggttta aacgttgata aaagatgttt
     6361 aaatccttaa tatttccatg acaaatataa caattgatga gataataaca aagtgaaatt
     6421 tgaaatcaaa aaggagagca gatatccatg aagggaatca ttcttgctgg gggcagcgga
     6481 acacgtctgt accctttaac aaaggcaaca tcgaaacaat tgatgccgat ttatgacaaa
     6541 ccaatgattt attatccaat gtctactctg atgttggcgg gaatcaaaga aattctgatt
     6601 atttcaacgc cacaagatac accacgtttc aaggaattat ttggaaacgg aaatgattta
     6661 ggactgcaga tcgaatatgc agtacaagaa agtccagatg gattggcaca agcgtttatc
     6721 attggagaag aatttattgg agatgatagt gtctgcttgg tattagggga caatatttac
     6781 tatggtggcg gtctgtctaa aatgttgcaa cgagcagctt caaaagatac aggcgcgaca
     6841 gtatttggct atcatgtcaa tgatccagaa cgctttggtg tagtagaatt tgatgagaat
     6901 atgcaagctt tgtcgattga agaaaagcct gctcagccaa aatcaaatta cgctgtaact
     6961 ggcctttatt tttatgacaa tgaggtaatt tctatcgcta aaggtatcaa accttcagaa
     7021 cgtggagaac tagagattac ggatgtcaat aaagcatatt tggataaagg aaaactatcc
     7081 gtagaactta tgggacgcgg atttgcttgg cttgatacag gaacacatga atcattgctt
     7141 gaagcatcta cctttatcga aacaattgaa aaacgtcaga acttaaaagt ggcttgtttg
     7201 gaagaaattg cttaccgtat gggctacatc gataaggaac aattgctggc ccttgcacag
     7261 ccattgaaaa aaaatcaata cggtcaatat ttattgaatt tggccgctga ataaggagtc
     7321 cttacagatg aaagtaacag atacaaaatt aacagatgtc aaaatcgtag aaatggacgt
     7381 ctttggcgat catcgcggtt tcttcacaga aagttattca aaagcaaaat ttgcagaaca
     7441 tggattgaaa tatgactttg ttcaagacaa ccattcacta tcagctgaag ctggtgtcct
     7501 tcgggggctt catttccaaa aaggagaagc tgcacagaca aaattgattc gggtagtcac
     7561 tggagcagtt ttagatgtag tagtggatat ccgcaaaggt agcccgactt atggtcaatg
     7621 ggacggattt atcttatctg aacataatca tcgacagttg cttgtaccta aaggatatgc
     7681 ccatggattc gttactttga caccaaatgt gaacttcctt tataagtgtg ataattacta
     7741 taatgcagaa gcagatgggg gcatcgcatt tgatgatcca gatttagcga ttgattggcc
     7801 aattgatcca tcaagagcga ttatgtcgga aaaagatcac cgtcatccga cattaaaaga
     7861 atttgaagca gaaaatccat ttgtttacgg agaaatctaa gaattaagga gaaattttct
     7921 tatgaaaaac atcattgtta ccggaggtgc cggattcatc ggctctaatt tcgttcatta
     7981 cgtggtaaac aatcatccag aagtgcatgt cactgttttg gataaactga cttatgcagg
     8041 aaacaaagag aacttggctg gacttcctag cgatcgcgta gaattggtcg taggagatgt
     8101 tgcagatgca gaattagtgg accgtctagt aaaagaagcg gacgcagttg ttcattacgc
     8161 ggcagaatcc cataacgata attcattaaa agatcctttc ccatttgtac aaacgaatat
     8221 cattggtacg tatacacttt tagaagcttg ccgcaagtat gatgtacgct atcatcacgt
     8281 atctactgac gaggtttacg gcgatcttcc attacgtgaa gacctgccag gacatgggga
     8341 aggcgaagga gaaaaattca ctgcggaaac accatataat ccttcaagtc catattcttc
     8401 tacaaaagct ggttcagatc tgttagtaaa agcatgggtg cgttcttttg gcttacgtgc
     8461 aaccatttca aactgttcaa acaactatgg tccttatcag catattgaaa aatttattcc
     8521 tcgccaagta acgaatatct taagcggtat tcgtccaaaa ttatatggcg aaggaaagaa
     8581 tgttcgtgac tggatccata cgaatgatca ttcttcagca gtgtggctga ttttgacgaa
     8641 aggcagaatt ggcgaaacct atctgatcgg tgcagacggt gaagaagata ataagaccgt
     8701 gatggaattg atcttagaaa tgatgggtca accaaaagat gcgtacgacc atgtaaacga
     8761 ccgtgcagga cacgacttgc gttatgcaat cgattcgaca aaattacggg aagagttagg
     8821 atggaagcct gagtttacga acttccgtga tgggttggct gacacgatca aatggtacga
     8881 agaacatgaa gactggtgga aaaaagaaaa agaggccgtt gaagcagcat atgccaaaaa
     8941 tggacaataa tacagagaaa atgtcactgt attaatggaa aaacacatgt gaggcaggcg
     9001 ctcgcctgtc tcttttttaa aataaaaatc aaggagcgga taatcatatg tttttattaa
     9061 ctggaggaaa tgggcaacta ggtacagaat tgcgccattt attagatgaa aaaaatctgc
     9121 aatatgtttc aacagatgca aaagacttgg atatcacaga tgccgagaaa acaatggctt
     9181 acatcacaga attaaaacct gatgttattt tccattgtgc agcttacaca gcagtagata
     9241 aagcagaaga agaagcaaaa gaattagatg agaagatcaa tgttgatggt acaagaaatg
     9301 tagcacttgc agcaaaagct gtgaatgctc aattcgtcta tatcagtaca gactatgttt
     9361 tcgatggaaa aaacaaaaat gtagaatacg aagtagacga ccaaacgaat ccactaaatg
     9421 aatatggtcg tacgaaatta ttaggcgaaa aagcagtaga agagatttta gaagactatt
     9481 atatcatacg aacttcttgg gttttcggga tctatggaca caatttcgtc ttcacgatgc
     9541 aacgcctagc ggaaacccgc gacaaactga ctgtagtaaa tgaccagttt gggcgaccaa
     9601 cttggacacg tactttggca gaatttatgg tatatgtcat cgaagaaaaa gcaccatttg
     9661 gtatttatca tttgtcgaac gaaaatagct gttcttggta tgaattcgca aaagaaatat
     9721 tgaaagatac agatgtagaa gttgcacctg ttacgtcaga agaatttccg caaaaagcaa
     9781 cacgtccgca gtattcagtc atgagcctga aaaagacaga agagttagga tttgtcatac
     9841 caacttggca agaagcactt gcgcaaatgc tggaagctgc caaaaaaatg aataagtaat
     9901 ttccttttat caaatagaat ttggagcatg atatggaaaa acaaacaaga agtgcacgac
     9961 gaaaagaaaa gccaaaagcg aaccaggcag attcgaattt ggtgcttgac ctgtttctaa
    10021 aactccgcta tcttattggc gttttagtca tcgtggtcat cgttactttt aatttaaacg
    10081 gaagttcact tggtgtttgg gataaatatg tgtcgcaaag agacgatggg aaaaaaactg
    10141 atgtgatttt tggacagaat cgggaagtgc ggtcagacga atggctggtg cagacacctt
    10201 tttacctctc acaagctgaa gaggactttc cgttggtgaa cgaggattat tcattaaacg
    10261 gacaaaacat gatcattgcg tataattctc ctgcaaagga tattacggtt atcggaaaac
    10321 cattcaactg gggattcttt ttcctcggaa gagatcgagg actttccttt tattgggcga
    10381 tgaaattagt cgtcatggtc ttgcttggat tcgaagtact gatgatatta acgaagagaa
    10441 aaaaagctct atcgctaatc ggtgcatttg cgctgacatt ttctccagca gtccagtggt
    10501 ggttcatgca acatgtgggc gatttgattt tctttacttt gggactgatg actgcttttt
    10561 atcattattt ctacaatcat gataaaaaat ggctacgaac gttgatgatg cttttggtgg
    10621 ttattttcgg tattgggttt attttagtga tttacccagc ccatcaagtg atgctggcgt
    10681 acttgctgat tttttatttt gttggcctgc ttatttacta tagcaagaaa gtttcatggg
    10741 atctgttgga tgtagtgttg attggagggg cagttttatt tattggcgga gtcatggttc
    10801 atttctggct aacgtcaaaa gacgcattgt tagcttcttt gaatacctta tatccaggaa
    10861 aacgggtaag tactggagga aagtggacga ttggcgaatt tttttctttc cttacaaatt
    10921 ggaaaattcc ttttgaagat atcaactatt cgaataactc tgaagtggcc ctgttctatc
    10981 acttttttcc aactgtattc ctagcaagtc catttgtgtt atttggcaaa aaagatagcg
    11041 aacaaaagtt actgggacgt attttgatga ttttttgtct gttttctatc ttttggatta
    11101 ccgttgggtt gccaaaatgg ctagcagaaa tcactctgct gtcttatgtt cctccattaa
    11161 gagccatcct tacttttagt tttgcggctt gtttattatc gatctggttt atcgcttata
    11221 tttggagaga agatgttatt cctatttggt ataaattcat tttgttggca gtaaatgcat
    11281 ggtcttattt ctatgcgatt acgcattcga aaatagataa ttatttttcg gattttgaaa
    11341 ccatcgcagt tgctgtgttg ggaacagtga ttttagcatt tgcattattt ggctggagac
    11401 gcttgtttta cctcgctttt gccgccttag ttatcgtatc tggctttttc gtcaatccag
    11461 tcgtagaagg tacaggagcg atttttgaaa aaacactggc aaaagaaatc caaaaaatcg
    11521 atcaacaaga tcctggtaaa gtttggttgt ctgaagatga attatataac ttcaccccaa
    11581 cattgggagt gaaatccttc aatacagtac gcttttatcc agatatagct gcatggaagg
    11641 aaatcgatcc gaaagaagaa tacgagaagt attataatcg gtatgctcat acaagagctt
    11701 ttatcgctaa ggaagataca aagttcattt tagatcgtcc agatatgttt tcggtcacgt
    11761 tgaattttga agacgcagaa aaattaggga tcgactatgt gatcagtaaa cgaccattaa
    11821 ctgattacaa ccaattatat gaagcgcagt tcacgcagct atatggaccg gataaagacg
    11881 gttatatgat ttttaaagta gaatatccgg attatccaga tgtaccacaa acacaaactc
    11941 aggaaaatca gctagtcgta cagtaatagg ctagctgaga ataatcctga aatattagta
    12001 gaaaggagag tggagataat tcaagcaatc gtacaaaaat ttgtcaacaa aatgagtgtc
    12061 ggtttcttgc ttttgttgct gacgctagtc ttttttgttt gtacagcagg gttaggtttt
    12121 ccagcaactt tgtttatata taacaatagt tcattactta tcgcttttag tgtggctatt
    12181 ttgctcattt taaatgttta taaagcaaaa ggcgtcgatt ttctttatct aggtgttgcg
    12241 cttgcccttt tcattttctt ttcttacttt cgggaattaa gaaatgagtc tttatttgga
    12301 gatttactgt ttcctttgat tattttattt tgtttagtaa ttaaatggat cgagtggaca
    12361 aaatgggatc gcggtattta tctgattgtc tttacggtct tcctcggaat cacgttatat
    12421 cgtgtattta cagagatcca agtaccagaa ggacaaagca tctgggctcc aggcaattcg
    12481 ctttctgata tttggatcaa tacgaataca atcggaagtt ctttgatgac tcttgcttta
    12541 ttgatcagtg gatttgccag ttcttttgaa cgatggtatg tacgaatcat cggtgcagta
    12601 gcagttgttg cagcttttct cgggatttgg gtctgccaat ctagaggtgc attagtcgcg
    12661 ttgattgttt ttgcgatatt ggatctttta cctaaatcgt tgatgcgtgt cattcgtgcg
    12721 ccatttattg cttacacggt tacgattctt ttagctttgc cgatttctta tctggcggct
    12781 gtctctgaaa aagtcaattt gtttaccggt cgagaagata tttggcataa attctatcag
    12841 acgctaggag aaaaatctga acaagtttta ctaggaatga aaacatttat cttccaacga
    12901 ggaaaccaat ttttaggaaa ccacaatagt tataattcta ttttgaatat ctatggattg
    12961 ataggatttg ggattgctac tttgctgctt atccttttta ttggtcgctt aacgttgaaa
    13021 gcagatttat ccaacgggca gatgactttt atctgggcct tttttgcggt gatgatgcag
    13081 tcatttatgg aggatacatt gacttcatac ccatgggttc cgattattta tatcctgttg
    13141 gctatggccg ttcatcgata tgatgaacca gaagttgcgg aggaattcta tgttatggaa
    13201 gaggcatatg acgatatgac ttatgatgat acatcttatg aggaacaacc agatagcgct
    13261 cattcttcca ggatccaacg ctatcattga taggcacaaa atacggctct ttgtcaataa
    13321 ggactgatgg gttgtacaaa atcaaatctg ggtcagaatg aacctcattc tggctcagat
    13381 tttttgttat cttactttga ttaattgatt gatcaaaaag attctaat
//
LOCUS       DAXLPC010000071        12983 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.071, whole genome shotgun sequence.
ACCESSION   DAXLPC010000071 DAXLPC010000000
VERSION     DAXLPC010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.071"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..3044)
                     /locus_tag="ACF3UE_002029"
     CDS             complement(<1..3044)
                     /locus_tag="ACF3UE_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFD3635411.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPE
                     DKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPAGYHKVT
                     FTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTEF
                     VSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKVDVS
                     AAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
     gene            complement(3661..4095)
                     /locus_tag="ACF3UE_002030"
     CDS             complement(3661..4095)
                     /locus_tag="ACF3UE_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635412.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(4112..5317)
                     /locus_tag="ACF3UE_002031"
     CDS             complement(4112..5317)
                     /locus_tag="ACF3UE_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFD3635413.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            6011..6397
                     /locus_tag="ACF3UE_002032"
     CDS             6011..6397
                     /locus_tag="ACF3UE_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFD3635414.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            6491..6682
                     /locus_tag="ACF3UE_002033"
     CDS             6491..6682
                     /locus_tag="ACF3UE_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635415.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            7196..7528
                     /locus_tag="ACF3UE_002034"
     CDS             7196..7528
                     /locus_tag="ACF3UE_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3635416.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7438..7632
                     /locus_tag="ACF3UE_002035"
     CDS             7438..7632
                     /locus_tag="ACF3UE_002035"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3635417.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            7671..7817
                     /locus_tag="ACF3UE_002036"
     CDS             7671..7817
                     /locus_tag="ACF3UE_002036"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635418.1"
                     /translation="MMDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            8255..9595
                     /locus_tag="ACF3UE_002037"
                     /pseudo
     CDS             8255..9595
                     /locus_tag="ACF3UE_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9836..11452)
                     /locus_tag="ACF3UE_002038"
     CDS             complement(9836..11452)
                     /locus_tag="ACF3UE_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFD3635419.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            11570..11788
                     /locus_tag="ACF3UE_002039"
     CDS             11570..11788
                     /locus_tag="ACF3UE_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635420.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11983..12444
                     /locus_tag="ACF3UE_002040"
     CDS             11983..12444
                     /locus_tag="ACF3UE_002040"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3635421.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(12637..12876)
                     /locus_tag="ACF3UE_002041"
     CDS             complement(12637..12876)
                     /locus_tag="ACF3UE_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635422.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12900..>12983)
                     /locus_tag="ACF3UE_002042"
     CDS             complement(12900..>12983)
                     /locus_tag="ACF3UE_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HFD3635423.1"
                     /translation="YNELHNWPTFYPASLSKHEIAQEMMAH"
BASE COUNT         4188 a         2445 c         1988 g         4362 t
ORIGIN      
        1 ccttctactg ttggctcata tttatcggcg tcagaacgat tgtctgtcac tgtaacatct
       61 acttcaactt catcagatga tccatctgga tatgtcacta caacagtccc ttttttattt
      121 ccagctgcgc taacatctac tttttctttc caagtatact tagtatcttt tggtaaatct
      181 tctttgttct taattccctc aaatgcgtct ggttccttat tcaattctgt agtcactttt
      241 tgaccttcag gattatattt gtcagcgtca gatttatcat ccagttttgt tgcacttgat
      301 acaaattctg tatcatctgc tgtaattggt tgagttgctt cctctggcca tttcgcatct
      361 gtataaccat cttttgcttt caacactgga agtttatctt ctggtaagct tacgccgtct
      421 ttcactgcaa agactgttgt tccactttca atacttgttc cttctcctgc ggtgaaggtt
      481 actttgtggt agcctgcagg aatgttttct cctggatttt caatgatatc atccagtttt
      541 gttgcacttg atacaaattc tgtatcatct gctgtaattg gttgagttgc ttcttctggc
      601 catttcgcat ctgtataacc atcttttgct ttcaacactg gaagtttatc ttctggcaag
      661 cttacgccgt ctttcactgc aaagactgtt gttccacttt caatacttgt tccttcccct
      721 gcggtgaagg ttactttgtg gtagcctgca ggaatgtttt ctcctggatt ttcataaata
      781 tctttactta cagttactgc taaatcggtc gtgcctacag aaccatcttg gtaaacaatt
      841 ttaataggaa ttgttccagt aatcggctcc gattctccta cacctttagc tggagtgaat
      901 gtaacaatac cagtgtttgc atcaacactt gcattaccga agtacttatt atagacatct
      961 gaaattgaaa aggcatcttt agctaaagga acatctggtt tatcaaatgt aggttttcca
     1021 ctttgaactg tcgtttctgg agttgttgtt ataggtacgt atgttgcatc attttccata
     1081 gcttgagaag cttttacagc aaactctaca tccacgtcga aagttcgatt tccgatctta
     1141 acagttacaa tacctttcgt actatcagta acgttagaag tatcaggctc tgttttccat
     1201 gaatactctg catcttcagg taagttttta ttattccgaa ttgattcttt agcatctggt
     1261 ttaaatccaa ctaccacggt ttgtttatca accgcttttg gtgattcctt aataacggtt
     1321 gaaccttctt ctggtttatc aaaacctgga gaaacgattt ggatttttaa ttcatctttc
     1381 gcgattaatt tacttgaatc tacacccgta aattcaaatt ctacagtatc tgaaattgga
     1441 gccccatctt tttcatttgg agcgatagtt ttttctgcta atacagtacc ttctttatca
     1501 acaagttggg ctttgtgacc tgttcccgct aactcgtgga tgaatacttt ccccttaact
     1561 gttgtgtcaa catcatatac ttcttctaat tcaggtttcc cgatatatgg attcgtgtct
     1621 ccgctctctt ctttatcgtc agggtttcca tcaccatcaa tatcttgcaa ataataataa
     1681 cctgttccat aagtgttctg gattaatttt ttattcgtat ccgacaacca agaatcaaag
     1741 atgaaatctt caccaaatgg tttattttct tcaacttgtg ctgttgcttt catatcttct
     1801 aagatttcat ctaatggctt agtcaattgt aaaacatatc gaataacgac tggacgtgga
     1861 cttgcattag caaaatcgat aagtttagtt aaatcattat tagttattga acctatgcca
     1921 taattttcat gaccttcccg tcgctcgatt gctaaatcag ctacttttgt tccggattca
     1981 aacgaaacat catatgttac tttgtcagcc tgaaccatgt gcatctgtat acccgctaca
     2041 tatggaacta atcgttcatc aattttgtaa ttagcatacc aaggcgtgcc ctttgcggaa
     2101 gatgaatatg agaaattata atttttcgtt aacttatgat ctaagattat agctccatta
     2161 gcacctgtgg atcctgaacc atcttttgtt tgagtattag gtttctcata ttttgcactt
     2221 actgatccat gtttaaactg gtcaggatta ttttcagata catctaagct attatagaaa
     2281 tcatctgaat ctgttaaaaa gtagcccgta ctatcaatac ccggtacaat tttatcatcg
     2341 tcttgatgac ttaccaagta gattcgatac attaaacgat cggtcttgag attgtctatg
     2401 cctatctctt taaaaatttc atctaggctc ttttcaaacg taattacccc attaggagcg
     2461 gtttgcgtat cggttgtttc tgccccagca aataatccat cacttgcacg aatataattg
     2521 accttccaaa tatttgtagg tctacccagc gaatcattaa ttcttacaaa ggtccgtcta
     2581 gaagatccaa ttcctttctt tggatcgacc tgaatttttt ctacatattt agctaatcgt
     2641 tcatctaatt gaagacggat ttcccagttt ttagttgatg ctgcaatatt atgttttccg
     2701 taaacttcaa atccaattgt attgcctttt agtgtgtctc cagttagttc ttgaggacta
     2761 aattgtaaat ccgaaaagtt ataatttttc gtataaccag gattctcctg aaaagtattc
     2821 cccgaagcta ctttgtcacc tacttgtacg gagcttatcg ctgtttcaag tgggctgctt
     2881 ggagaaattt catcttgtgc tttaactagt tcagttgttc ccaagacaag accaacacca
     2941 atcaaaacag atgcaacccc aacacttaat tttttgatac tgtacttcaa tactcgtttc
     3001 tttgtttttt ctagaaatac tctcttatta ttcttgctaa ccattattca aatcaactcc
     3061 cttaataatt actttcctag taagaataaa agataaatct gatacgtatt attcacagaa
     3121 taggaatctt actaacctta tgttaactaa tttacttaga gaatttcatg aacattacaa
     3181 caaaaaaagt acatttcttc atgttttttt cggatatttg tgctttttaa ccattcagca
     3241 gctgaaaaca tataaaaaga tatgtatgta ttctttctga aattaagttc atttctatgc
     3301 gatgaagcat gttttcaaaa tattaccctt tcttagatta aacttcagag tattcaaata
     3361 acggaataag gagccttatc ccgcattact gaatgagact gtgacataag taaaaaggtg
     3421 acttcaaatt ccttcttcgg aatttgaaat caccttcttt ataattataa agtatcggtt
     3481 tcacagcatt tctgaatgat tcctagaatc ttaaacgaat gattggagtt atcaacattt
     3541 tttcactcgt ttttagcgaa acaaaaaatg acatttgtca cagcctcatt aaattattga
     3601 ttctttttct ttataattga attgtccata tttaaagtgt ctagtactct acatgaataa
     3661 ttaattgctt tcactcaaat acttataatc tattaacttg tagttgttta acttttctga
     3721 aaaagttaga cccacgtaat aatcttccca gctttctctt tcaattaact gatccaattt
     3781 ttgataatcc ataaattcat catgtatcaa aaagaataaa taacttgata ttttagcatc
     3841 tagcttaatc agattaaata atgtttgttt aaaattgcta ccattaatat gactgataga
     3901 ttctctagct tcttcacata aactttttac tttattaatt actactttgt catattcatt
     3961 taacacacta ttattaccat tacttagacg ctcagattct acgaaacaac tcaaatcaga
     4021 aatttcccaa aaaaattttt tgttaaaatc caatttcctc aactcctcca aactacgtaa
     4081 atgatatagt ctcataataa aataaaacct ctcagctaat gttgttgaaa ttgtccacta
     4141 aacctaattg atattgctta ggagatacac ctgcgtactt tttgaatact ctcgaaaagt
     4201 gtgaagaatc tgaaaatcct aaacctaaag aaacttcact gatagtatgg tttgatttca
     4261 acattatttt agccgtagaa atttttcgct tagagatata attataaatc gtaatatgca
     4321 tttcattctt aaagctttct cttaatttag tttcacttac agaaaaataa ttagctattt
     4381 cctttacagt aattctttta tagatattta agccgatgaa ttgaacgaca gaagaaatta
     4441 agggagaaag atgctctatc ttagtttttc cgatttcctt agtataataa acaatcccag
     4501 aatccctcac ttttaagacc tcaggtaacg atacagctaa ttcgttttct tgtatcaaag
     4561 catctctact ttgatacgct tctattatat ccattcctaa tgttatagac gtttgtgcta
     4621 acttttcaaa aacaatgata gaataatttt tttcagaccg aatcgtatct ccactaacac
     4681 ttggaattat tccattactc agattaaaaa ccatgttttc taaatttcga atatctccat
     4741 ttttaacata ttccagtatt ttattttcat aaagaaacag atatatttct ggatcgtaat
     4801 tttgtgataa cagattatct attttgattt gctcgatagt tttacttaga ttttctgtat
     4861 attcaattaa cggttcatgg aatagatctt ctatttttcc agtaaaaaaa taatgaacta
     4921 aaatcagaat atctcgaatg tctcctaaag aatacaaagt caaattttgc aatgaattat
     4981 agagtcgttc tctatcagcc attgcaacat tcaaattgtt catttttagt ttaaaaaaaa
     5041 ctttatcaat attatttgct ctaaatggac caaataagta atatctggtt ttaaacatgt
     5101 atagaagaaa catctcatta aaatcaccag taaagaaatg gaaatcttta gtttttttaa
     5161 tattatcagt tagtaacttt ttataatcat aaaaaaaata agtagttcta tctgagcgat
     5221 actcttttat aatactgaat tcggaattaa aaaccacgat aggtaacttt aaacaaacat
     5281 gaagagactt taataagact tctttatctg aaaacacttt tgtttctctc tttcctttct
     5341 acatcattaa atagtatttt atacgttatc taaaatacta ttcctctgtc aaaataagct
     5401 aacttacttc attataaaat atccacttat cgctttcatg tatattccac cgtaaaaagt
     5461 acattttatc accgagaact catcattttt catcatgatg aatactattt acatatatct
     5521 agttcaaaga caataattat tatgatccgt tattatctaa gcactataca gataatagga
     5581 atttttcgtt tctaaatatt ccaatttggg aatccaataa aaattttcgt tcaaatacgt
     5641 gtctattcga actcttttct agttgttaat tatgaagggg gaagaaataa aaaatacaat
     5701 ctatacacga ataagaatat tatccaaaag gaggttttag aaaagattta ttatacgtaa
     5761 aaagctcaag acattttctt agccataagg acatgtttga tatttaagaa gatatatgaa
     5821 ttttcttttc taagtataaa gataactatc cattatcaac taaaaaaaca tttttgaaaa
     5881 taaacatcag cagtcctatc aatgcatgtg agcttataga agttattcgc agcgcagcat
     5941 aattgcatta gcttcttttc gtgttttttg cctcttttcc ctttaaatct taatggagga
     6001 ggtgtgcaat atgtcagata acgacgaacg cgtaaatgcc cagttgattc gattctttga
     6061 aaaggtcatt ttgaacaccg ctaatactta ttataaaaaa caagaagaaa ttcaaaaaca
     6121 tgaacaactt gatcaactcc caccatattt gtttactaaa gatactataa aatttaaaca
     6181 accgattaat gttttaaatg tgactctcct tgttgaagat ataaaattag caaaaatcct
     6241 tcctttgttg aaagaacctg aacaaatttt tcttatcgaa aaatttatct ttgataaaac
     6301 tgataaagaa attggaaagg ttctggggat tacaagacag ggtgcgacaa atttaaaaca
     6361 tcgactttac aaaaaaattc aaaaaatgct ggtttaatat ctgcataata actaattttg
     6421 tatgcttctt tgctcgttct cctccttccc aaagaaatag attataagtc catgggaaga
     6481 aggtagattt atgaattctt taaaagaaga tttcatttta gcaaaggctg gaaatgaaga
     6541 agctgttgag gcaattctca aaagatttag ctctttgatt cataagcaat cctggagaac
     6601 tggaaaatat gatcaagatt gttatcaaga atgtatgctt gcaatatatc tagctatctc
     6661 gaaattcgaa attaaagaat aactcaacta agggagtctg tgacataagt aaaaagatag
     6721 tttcaaattt cgaacaataa atttgaaact atcttcttta taattataaa gtatcgattt
     6781 tacagcgttc tataatgatt catagaatct aaaacgaatg attttaatta tcaacgtttt
     6841 ttaattcgtt tttagcttaa aaataacttt tgtcacagtc tcactcctaa aattacttta
     6901 tttacgtatg aagtgggcag gaggtcgaat ccagaactgg gctatggtac ttcaacgagg
     6961 acttctcctc tagaattgaa aagcatgcga tttaccttcc gtaacgacgg tagatttatt
     7021 caactatgtg tccaatcaaa atttgtctga tttcaaaaat agtcaagaga attttggttg
     7081 ttaaaaactc ttatctatca acttccacag tttagttgac aaaccctgat actaagttgg
     7141 gctatgatac acttttcttg actatcagtt acgttaccgg aaggaatgaa ctctattgag
     7201 aaaaacatat gatcgtaaat ttaaactaaa gatttcacag gatatccttg agaaaaaagt
     7261 aactaccaag aaaattgctg aagaatacaa tatctctcgt ccaacaattt cccgatgggt
     7321 ttcagaatat cgtcgatacg ggaaaaatgc ttttgctgga caaggaaaaa gattacctga
     7381 taaagcagat ttctacattc ttgaacagga aaataaacga ctaaaagagg aagacgagtg
     7441 ttctacgaac acaaagatcg atacggatct ccagggatca ctcaaaaact ttacgatgaa
     7501 ggaatcgaaa tcaataaacg tgttgtagct gttcttatgc gtgaaatgaa tttatgcaca
     7561 agaggatttc atcgacgcaa atcttctcat ggtagagaaa aaacaatcaa agaaatggta
     7621 aaaaaatgtt gaatcgataa tttgaacaga accaaattga tgctgtttgg gtgatggata
     7681 ttacttacat tccatgtaat gacggtcgcc tctatttgtc cacctatatt gacttagcaa
     7741 ctcgtattct acgttactat atggtagatt cacacatgaa aaaagagatt gtcgtccgtc
     7801 cattacaaat ttattaagga gaattgccta cggtaattca ttccgataga ggtagccagc
     7861 atcggtcttt tatttatcaa gagctgttga acgaccacca catcacacat tcagtgagcc
     7921 aaactgggac tcctgttgac aatgcagtaa ttgaagcgtt tcatcgatca atcaaatgag
     7981 aattaatcga ctccaacaaa tataaaagta aaatagagat gaaggtgtta atccaagatt
     8041 atttagaaga ctactaccca aacaaaagaa tccatacaaa atttatgatg actccttgac
     8101 aatttgaagc gaagaaaata agggatctat aatatctagt gttggtgacg ccttctgttg
     8161 ccaatacttt ttcttttttc taataaacgc aaacagacac cttaaaatcc tttagaataa
     8221 agtcgacgaa aaccattcaa aggagtgttt caagatgtcc tattcagagt ttaccaaaga
     8281 gttactagat attctagacc taaatcttat ctttcatgaa gatgcctttc gcaaagagcg
     8341 aatcaatgac gaaacatgtt ttgtttttga tggcacattg acctatcaac cggaggaatg
     8401 ctttcatcgc cactatcaaa atgaacaaac gatcattaaa tagggctgga aaaaagtatc
     8461 catcttattg aatgatgtca gtaactacaa gaccattctg cggattaaca aacagcgctt
     8521 caaatgtaaa cactgtggaa agactttttt agcagaagat tcagttagtg atcgtcgctg
     8581 ctccattgct cgcagagtca aacaagccat tcttgagcta ttaagcgaac ctctttctat
     8641 gtctttgatc gcacgtatga agcacatttc tccgaccact gtcattcgaa tacttcgcag
     8701 ccttcggcct aaaaccattt ctttgagcca gctgttacca gaagtggtgt gtttcgatga
     8761 attcaaatca gtgaaaaatg tctcgggagc catgagcttt gtcatgatgg acggcaagac
     8821 ccatcaactg attgatattg tggaaaatcg gcaactcaat cctttacgcg actatttctt
     8881 gcgctaccct ataaaagtcc gtgaacaagt gcgtctagtg gtttcagatt tctatacacc
     8941 ctatcgcaca ttggtgaaag agtgttttcc gaatgcccga atcgtcgccg atcgctttca
     9001 tattagccaa cacattggtc gggcttttac caaccaccga attcaagtaa tgaagacctt
     9061 taaaaaaggg gatcgtcggt cgaagcactt aaagaaatac tggaaactac ttcaaaagaa
     9121 tgcgtgggaa ttgaaaggtc agcatcgcta ctggcgtccg tcatttcgag atcatctgac
     9181 agaagcagag atagtcgatc ggctattatc ttatgatgat tccttaaagc gaggctacga
     9241 agtctaccag gattttcttt ccgttatcag aagacaagat gttcctgaat tcgtcgcgct
     9301 cctaaaagaa gactacaagg agttgccaga gcactaccaa ccagtgttca cgaccttcaa
     9361 gaaataccaa acagaaatca aacgagcgtt gcgcgttccc tattccaacg gccctataga
     9421 atgtttgaat aaccatatca aagtactaaa acgaattgcc tatggctata gaaactttca
     9481 aaactaccga gaacgaatct ttttatatcg aggaaaatat tttaagaaaa ctaagaatac
     9541 tacccaactg actaaagcca gaacaacaac acggctagac aagatagctg tctagccgtg
     9601 tgagtatctc gattattcta ttgaatttct tcaccaacac tcattgacga agagccaaaa
     9661 taagtaatct aaccgactgt taactaaacc attgcaggtc ccgttaaaga tacttgtgcc
     9721 tgttgtcacc gcttcttttt cttgtccaca agcgcttaac acacttaata aagcccctgc
     9781 tattattaat aataatatct ttttcttatt aaaaacctcc tcatctattt ccagattagt
     9841 aaatgtagta atctgtgctt tcttttttct caatactaat aactaactta tggggtaaac
     9901 aaatactcgt ttgaccgggt tttgagatcc atccagttct aaccgcgatt tgatcaggac
     9961 tattatcttc tttaactcga attcttccat ctttaatctc aacaatatta tattgtccct
    10021 tcgcaggatg ataattcacg agtttatgat tgatcttatc caaatcgaag cgatccattt
    10081 ccttgccatc aattcgaacg atggcatatt tgatagcatc ttcagttgtt tcattctcct
    10141 tttctataga gaatacaaat aagggaataa aagaggtaat aatcaaaatg ccaataatta
    10201 tgacatcgcc tatcttgaca ccagcttttc ttaaaaattt cattaacgat atctggctaa
    10261 acatattaga ctttttccat ggaaatggtg aaatttttcg gaaattatct gcattaagag
    10321 aatcagttaa acaaccctca agttgttcct taatacattg ttgatccatc ttcataccaa
    10381 taaaaactag tttattaatg cgttcaccaa acaacggatg ccaggcttcc ttcaattcgg
    10441 gatttttttg tataatcatt tgacactcaa ttttaggtaa actagctacc caataattta
    10501 atgattcaat acttttatag ctacccgatg tttcaaagat cgtcgaaaaa tcactatgtt
    10561 gggcaaacca aagaaaccct tttgctcttg taatattgcc aggaaaattt ttatccgtaa
    10621 gatgggcaaa tttttgtgcg tcaaggagta accgatttcg atagataaaa cttgagatac
    10681 catattcttc tgtttcagga atatgatttt gatagccaag ctctaactct ttgaaccagc
    10741 ccactgaata ggaagtctca tctatattaa aaagatttgt atttagaatt ttcgataagt
    10801 ctacttcacc tttaattgtc ctaattattt tggcattgga ctgtaactta gcaattagac
    10861 cgttaatttt gtaaatcgtc ttggttgaca ctaagtcact attatttaaa agtaatatgt
    10921 tacaacactc gaattgatca attaacaagc cacgaatatc ctgttcttct tcaactacat
    10981 taccttcagc ttttctttcc tgaatctttt cacccgtttc gaaattatcc caaaaacgtt
    11041 ttacatccac tactataata atggcaccaa tctctaatcg ttgggtcaaa tcaatgtcta
    11101 aagggttttt agctaatata attgcttgaa taattggaat tggtttgctg attcctgaag
    11161 cttcaataac aatttgattc aagtcagaaa attgcactaa ttgatctagt tcaacaatca
    11221 aatcttcgcg taatgtacaa caaatgcatc cattcggcat cgaaacaagt ttttctccag
    11281 ttcttttaaa acctttcttg tcgactaata ccccatcaac atttacttcc cctatgtcat
    11341 ttacaatgac agcaatttcc tttccgtgat caccgtacag aatatgattt agaagtatcg
    11401 tttttcctga accaagatag ccagttaaga ttgtaatagg tatttttttc atagggaacc
    11461 tctttctata ccttgaattt acactttaag tgcaacacat aaaaatgagt cataatcgat
    11521 atccaactag tataagtttg tcgagaacac tcctagaagg aaaataatta tgagccagta
    11581 tcgtcatctt actatactcg aacgagaaag aatctttctg cttcacgaag aaggattttc
    11641 tattagtata attggcaacg acattcagca tagcccgttt actattttac atgaactgag
    11701 aagaaacaag aaaaaaacta ttcaccttcc aaagcggaaa aaaattatgc ttatcgaaga
    11761 aaaaaatgcg gacgttatca cattctaaat gatccgtgag tttggtcaat tgttcgtcat
    11821 ttatttgtcg attttcagtg gtcgccagag gaaatctcga atcgtttgaa gcatgaacat
    11881 atggactttt caattagttt tatcacgatc taacgtgcaa tttgcaatga tcttttcgat
    11941 acagaacccc tctcacacgg caataaaggc ctgatccgtt cattgcacca tcgaggaaaa
    12001 acaagacata caaaaaatca tgtcgagtct cgtggaaaga tttgccttac tcattcgatc
    12061 catggccgtc caaaatccgc agatgataga agtgattttg gtcattggaa agccgatatt
    12121 gtagctggca aaactggtgg tacttgttta gtgactttga cagacagaaa atcatgcttc
    12181 cttttagcag gaaagaaggt ccccagaaag aaagccgctt atgtgagcga gaaaatgatt
    12241 gaacttttaa gcagtattcc aaatgaggcg gtcaaaacga tcactccaga tagaggaaaa
    12301 gaattctcca atcatttcgc agttacagaa gcattgaata atatgccctt ttattttcca
    12361 gatcctcatg cccttggcaa caatgaacaa attaaaatac gaatagactc attcgagaat
    12421 acttgccaaa atcgaaagag atagctacgg tagataactc aacgataaat cagatgattg
    12481 aaaaactgaa taacagacct agaaagtgtt tagattggag aacaccttat gaagtcttct
    12541 ttgataaagt gttgcgcttg atttgacaat tcaagacata ataaaaagca gatcaaatcc
    12601 aaataaggga aaaatgatct actctggtat tatcaattaa ttggccaagc tattatgccg
    12661 ttttgctaaa cgtctacttc ttccagtatt gaccttgata aaacaacaat caggatcccg
    12721 ttttaatact ctatgaactg tgtcaatact aacatgtaaa gttgcagcaa tatcagctaa
    12781 tgtactccca tttaatctca tttgctttgc aaatcgataa cgccgataag catcaatatt
    12841 cttggaatcc atagacaata atacttttct taccatgtat ttcctccaaa aattgaattt
    12901 taatgagcca tcatttcttg agcaatttca tgtttagaca atgaagctgg atagaaagta
    12961 ggccaattat gcaattcatt ata
//
LOCUS       DAXLPC010000072        12951 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.072, whole genome shotgun sequence.
ACCESSION   DAXLPC010000072 DAXLPC010000000
VERSION     DAXLPC010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.072"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..426
                     /locus_tag="ACF3UE_002043"
     CDS             <1..426
                     /locus_tag="ACF3UE_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFD3635424.1"
                     /translation="AVFILFGVLFYTQIATSEKGFNFDWQTTLFVSVIYFALLLGIVI
                     AYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGLLPKFMKVADLDDAPGL
                     MLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            435..662
                     /locus_tag="ACF3UE_002044"
     CDS             435..662
                     /locus_tag="ACF3UE_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635425.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            1298..1669
                     /locus_tag="ACF3UE_002045"
     CDS             1298..1669
                     /locus_tag="ACF3UE_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635426.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(1925..2167)
                     /locus_tag="ACF3UE_002046"
     CDS             complement(1925..2167)
                     /locus_tag="ACF3UE_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3635427.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(2199..3101)
                     /locus_tag="ACF3UE_002047"
     CDS             complement(2199..3101)
                     /locus_tag="ACF3UE_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3635428.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(3114..3302)
                     /locus_tag="ACF3UE_002048"
     CDS             complement(3114..3302)
                     /locus_tag="ACF3UE_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFD3635429.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(3316..3879)
                     /gene="amaP"
                     /locus_tag="ACF3UE_002049"
     CDS             complement(3316..3879)
                     /gene="amaP"
                     /locus_tag="ACF3UE_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFD3635430.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(3917..4810)
                     /locus_tag="ACF3UE_002050"
     CDS             complement(3917..4810)
                     /locus_tag="ACF3UE_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3635431.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(4888..5811)
                     /locus_tag="ACF3UE_002051"
     CDS             complement(4888..5811)
                     /locus_tag="ACF3UE_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD3635432.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(5860..6210)
                     /locus_tag="ACF3UE_002052"
     CDS             complement(5860..6210)
                     /locus_tag="ACF3UE_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFD3635433.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(6243..7145)
                     /locus_tag="ACF3UE_002053"
     CDS             complement(6243..7145)
                     /locus_tag="ACF3UE_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFD3635434.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(7138..7995)
                     /locus_tag="ACF3UE_002054"
     CDS             complement(7138..7995)
                     /locus_tag="ACF3UE_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFD3635435.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            8329..9138
                     /locus_tag="ACF3UE_002055"
     CDS             8329..9138
                     /locus_tag="ACF3UE_002055"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFD3635436.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            9178..9675
                     /locus_tag="ACF3UE_002056"
     CDS             9178..9675
                     /locus_tag="ACF3UE_002056"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFD3635437.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(10060..10133)
                     /locus_tag="ACF3UE_002057"
     tRNA            complement(10060..10133)
                     /locus_tag="ACF3UE_002057"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10097..10099),aa:Ile,seq:cat)
     gene            10320..10643
                     /locus_tag="ACF3UE_002058"
     CDS             10320..10643
                     /locus_tag="ACF3UE_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635438.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            10807..11061
                     /locus_tag="ACF3UE_002059"
     CDS             10807..11061
                     /locus_tag="ACF3UE_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635439.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            11131..11376
                     /locus_tag="ACF3UE_002060"
     CDS             11131..11376
                     /locus_tag="ACF3UE_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3635440.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            11452..11817
                     /locus_tag="ACF3UE_002061"
     CDS             11452..11817
                     /locus_tag="ACF3UE_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFD3635441.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(11878..12441)
                     /locus_tag="ACF3UE_002062"
     CDS             complement(11878..12441)
                     /locus_tag="ACF3UE_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635442.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         3749 a         2425 c         2181 g         4596 t
ORIGIN      
        1 gccgtattta ttttgttcgg cgtacttttt tatactcaga tcgctacaag cgaaaaagga
       61 ttcaattttg attggcagac cacattattt gtttctgtca tttactttgc ccttctccta
      121 gggatcgtta ttgcttattt cttattgaaa ctattgaaaa aaatcgaaga taaccaagct
      181 ttttccactc aaagcttaaa catactaaaa aaaatcgaac gaaccatttt gtttattggt
      241 ttcgcctttt ttggcttact tcctaaattt atgaaagtag cggatttaga cgatgctcca
      301 ggtttgatgt tggtaggaat cgctgtcgta ttcattcctt ttgcagtata cacattaaca
      361 agcgtgctgg aaaaactgct tgaacatgcg attttactta agacagatca tgatttgaca
      421 gtgtgaggtg cgacatggca attatcgtta atttagatgt agtattagct caaaaaaaaa
      481 tgagtgtgac tgaattgagt gagaaagtgg gcattacgat ggcaaacatc tctattctaa
      541 aaaatggaaa agcaaaagcc atccgttttt ccactctcga aaaaatctgc caagttttgg
      601 agtgtcaacc aggtgatttg ttgacctata aaaatgactc gaatactata ccagaagaat
      661 aaaataaagt agaacaaaca gtaaataaaa aataatctga atgatagatg tgtgagactt
      721 ttagaagtta tttacgtcta ttattcagat tttttatttc gattgaatac cgttttatct
      781 ataaataaga tatgtactga ctcatacaaa gggggccttt tcttctccat gtactatcac
      841 ttttcctgat acaactggtt tcctgttacg ttgtagttgg atctgctttt agtataatac
      901 tttattcatt ccaccagact gatagcagtt tgagcagtct aaataatcat gtagtattac
      961 aggccattct gtttcatacc ttgaagtgct taaaacttca gctaatggcc cattgtgtta
     1021 actcttactc cattcttttt tagtaagctc ccatatatac tgtaaagcct tctatatatt
     1081 atgtcatgtt gctttttaac atttactatg tagttttgat aaaatgattt gaataacagt
     1141 gatggacaat tcttttttat ttttaacatt attttgataa taatgattat ttatttaaaa
     1201 atacattaga taacatttgt tacgacacga aaaagcttca caaacaaata tcgttatttt
     1261 aaaatgaggg cgaactcaca caattaggag gaatagtatg ccatttattg tttacttttt
     1321 tctttcatta ctcgtgatct atattccatt accaacattt ttcctgctcg tcaatcgtct
     1381 agcagagcaa catgatacga ttgctgctct tacgaaactt tgtttacttc tatttgtttg
     1441 tctagattac tttacgagct attattggct aaaacagaca agagtaaaaa agagatatta
     1501 tttcttcctt gtctttttca atctctttga gtttctgatc cattgctttt tacttcatca
     1561 gtatcatacg atccatttgt ggatcatctg ggttttcaaa gtggtcgtat tattttgtat
     1621 gttcaccttt cctatctcaa gaaaatttag ggaggcattg ttttattaaa gaagcttctc
     1681 tgtatcaata aagacacatt taaggaaaaa cttttaaaaa tctaattggg aatttgcccg
     1741 cataaataag aggctgtgac aaaagtcttg tcacagcctc ttattccgta taaacagtgt
     1801 tcaaaagctt gcatcttcga taatatgccc aaccaaatga aaaatatgag aagctatttt
     1861 tgtttggctg ttcttattac ttgatgaaga acagcttttt cacgacctct ttttaaaagt
     1921 ctttttacag ttttcgagca aagaatgata cgattagtac taaaatgatg gcaccaatca
     1981 atgatggcac gattgccatt cctgcaatac ttggtcccca agaacctaat aatgcttgac
     2041 caagtgctga tccaactaaa cctgctacga catttgcaat aatccccatc gaagaacctt
     2101 tattcgtgat tgctcctgca attgctccga taattcctcc gacgataagt gaccaaataa
     2161 atcccatgtt tcgttcctcc taatgtttta cttccttatt actgaacccg tggttctgta
     2221 ttttctttta ctttttgtgc gccgcttcca gctgctgatt ttactttatc tgtttgattc
     2281 gaagcaaatt caccggtttt tttcgctgcg tcagttactt tgtcttgcac cgtttcttga
     2341 tctttttcaa attcttcttt tgttttgatg tccactacgt tagcgttgac ttcgatcact
     2401 tctaaatgtg tcatattttt tacttctttg ccgattactt cttgcatttc ttcaaagatt
     2461 ttttcgatat ctttgccata ttccacaatg acatccatat caactgctac ttgtttttta
     2521 ccgacttctg tttcgatccc agccgttaca ttatctgtat tcacaagttt tcctgccaca
     2581 ttagagaaga aaccaccgtt tgcagataat aaaccgtcta cttgttcaat tgcgattccg
     2641 atgatttttt gcacaacttt atcttcataa ttcagctcac cgcgcattga atcttcctgt
     2701 tcagaatcat gctttccttg gttatttgta tgatcagaac caagttttcc ttgtccgttt
     2761 gtgtggtcag aactaagttt ttcttgtgct ttcgcatggt cagaaggatg tttttgctct
     2821 tccacaggtt tagaaggatc gattgcatca tgttgttctg gaactttaga ttctggagtt
     2881 cctggatgat gaggtgcatg cttttctgca tcatgtttct tctcttctac tccttgttga
     2941 acgttaggga ctactggatc tggatgtgca gatactggtg ctgttttgtt cttttcatcg
     3001 ttcacaccat ttgattggtt tggtgtcgtt gggtctggat gtgcagacac tggtttttgg
     3061 ttgttcattt tattgttatt atttttgtta ttgttattca tggatgtttc ctcctaagat
     3121 ttaaaatagt gatctaagat tttcgtttgt ttcagataaa aaccgatagc gacgccgatc
     3181 gctgccatga tcaagatcaa taaggtcttg aaaaagccca cggtgatcca taaaacggct
     3241 aatatcaatc caagtacccc aaagatgata gggagcttgt atgtcgaaaa tagttctttc
     3301 atttttggtc cccccctatt ctactcgttt gcggtcattg cttcgtttag ctggttcttc
     3361 aaagcctgtg tatttcaccg atactttcac tggctctttt gttcccaata tgtgttgtac
     3421 ttcattttcg atttctttca tcaatgttcc tgttttacca atgagtgctg aagttcgttt
     3481 caactcccct tttacattga cggcgatctt gtttttcgtt gctttgacat ttacttttgg
     3541 tgaatggatg aattcatctt catgcaagtg agaacgaacc attccttcaa ttgctttttt
     3601 atccaacgtc aactccccat caccatgttt cagtagaaag tttccgattg tttttggata
     3661 aaacaggaaa acaagtaacg tgataattgt caaaatagca aatgcaacgg caagccaaaa
     3721 tacatattgt tgcacgtatg aattagtgat ggaaaagaat cgaaacttct ctagctgaaa
     3781 aggcaatgga taggttgcac ttaatagtat cgcaaacaaa agcacagata gcaaaagtaa
     3841 tgttccgatc actccgatcg tttttacacc tttattcatt ttcgcacctc ctcatagggg
     3901 tgaaacgatc aacttcttat aagttgatcg cttctccacc agttactccg taaatttggg
     3961 ctgtaacata acttgcttta ttcgatgcta agaaaacata aactggtgct aattctcctg
     4021 gctgacctgc acgttctagt aaactttgct gaccaaattc agggatcgaa tcagaaggtt
     4081 gtccttcgtc tagttgtaat ggtgtccaga ttggaccagg tgctacacca tttacacgga
     4141 ttcctttagg tgcaagctgt tttgctaaac cgatcgtaaa gttagcgatt gaagcttttg
     4201 ttgctgcgta atctaataaa tgttcgcttg gattgaatgc ttgaacagaa gttgttgtta
     4261 cgattgctcc tcctgctggg atatgcggaa cagcttcttt cactaaagca aacatagcga
     4321 tgatgtttat cataaatgtg tctttgactt gctcaagtgg taactcagca atagactgac
     4381 aagaaatttg ctgtcctgcg tttagtacca tcgtatctag cccgccaagt tcactcacgg
     4441 ctttatctat gatttcttta ggtgcttgtt cgtcacgaag atcaaaaggt agtaagacaa
     4501 tcttacgtcc tgcatctttc acgtattttg ctacttcctc tgcatctttt tcttctcctg
     4561 ggaagaattg aagagcgata tctgcccctt ctctagcaaa tgcaatcgct gctgcacgac
     4621 cgatccctga atctccacca gtgattagta cacggcggtt ttctagttga ttattgcctt
     4681 cataggattc ttctccacaa tcaggaacag gaatcatatt ctgctgtaaa gctggtgtat
     4741 cctgatcttg tttaggaaat ttctccgtat ggtacaagtt tcgcgggtcg attaattttg
     4801 gttctgtcat tgctgtattc ctcctagttt ttaaattgta ttgccaaaac aaatttcttt
     4861 gtttgatacc tgttttaaat agattcttta atttgtataa tctttccggt ataaatggta
     4921 acctaaaact actgctgcta tcaaagagcc aaagactacg agtataaagc ctagagcaga
     4981 acttttaccc ggtaatcctc ctgtattcat tccccaaatc cctgcgaaca acgccggaac
     5041 ggaaatgatt aatgcagctg aatctagata tttcatgata tgatttagat tattgtccat
     5101 catcccgttg aatagatcac caatactctc taataaatct cgatagatct cgatcatttt
     5161 ttctgtttgt cgctgtctca aatggacatc atagagtagc tgttcatcgt ctaaacgttt
     5221 gatgaaagtt tcagaattcc ataattgatc cattgtttcc cgttgatctc ttaaggtatg
     5281 atcgatatat acgatgtctc tttcaagatc tgcctgttta tacagttctt cattttccgt
     5341 tgttttacga gctgctttat ccaaagcgtc aattcgcttt ttcatctctc ttagttcttt
     5401 cacgtaatgg gtgtaaatat ctaataatgt atacgtgatg atcttttcaa acgagtttaa
     5461 atgatttcca tgctttgtca gcagccgatc cacaaattcg gtttttctat cgatacaagt
     5521 aatcaagaga ttatcggaaa gtacaaaaga tattggcgtt aatttttttt cgatacgatt
     5581 atctgactga tctagattaa tcactaccaa agaaaatgga tgctctagtt tcgtctcata
     5641 aaggcgctcc atccgagaaa cttcttccgg atattcggtt cctacgaaaa tatcatcagg
     5701 aagctcgaat tcttcgattg cttgctcaat ctcttcgggc tttgcactat caagtacgag
     5761 ccaattatat tttttttcat ctgtttctat tacattcttt tcttcatcca caaagtagta
     5821 tctcaatgta tacctccttt ttggactttc tcgaaactat tagctgaaga agcagttctt
     5881 taatttgata ttataatcga gtactgcgat ttcattttct aatgaaaagc tgtcaagctg
     5941 tttgttgaag tccatgttca atcgtttacc gaaataattt tgctctaatt tagatgtata
     6001 gatgtccaat aatggatgct cgattttagt cgcatattct ccaaattccg aaacaaaagg
     6061 aatgatttga aaaaagctgc cttttgcaaa agcacctttg tcccttagaa atggatcgga
     6121 atcattgata agcgcgagtg cgatttttgt attttcccca accttttcaa ttaacgtctc
     6181 tactgcattt ttagacattg taatttccat tcctactccc cctcttcagt tgttgtcttc
     6241 tattatttaa caactacatc tgtttttggt tgaacttttg catattttgg atatttaggg
     6301 aatttagcta cacaacggaa agccgtcatc cctgcatatt tttcgtaata tttcttcgtt
     6361 ggcccttcaa aatccttgct ccacggtttc acatgtcctg aaaaatggat aatgtaagga
     6421 ttgttgcgag tttcttcgta ttcacgttca cctgctgctg ttggatgttt ttttgctttt
     6481 gccatgatat agccttgtgc attccaacgc ggatgaagtg gtaaccaacg gtcatgtaag
     6541 atagcattta atgcatcttg gtcatggaat cgtaattttt ctggattatg ttcgatgaaa
     6601 tctaatactt tttgcgtaat attttcatct aaccattttt tcacattgat cagcatcaaa
     6661 cctgagttga aataacgcat tgatttagct gaaattttca ttttttccag tcgttgatgg
     6721 aacccagcgt cttcaacagc tgctacgatt gaatcaccga agtcaagacg ccataattta
     6781 gagatatctt gtaaagcgat catgtcgcaa tccatatata agatacgttc aacttctgtg
     6841 ccgcggaaca attccggaat cgcaatacga taataagctg tttctggaat acgatcgctg
     6901 attaccacat ttgtaaagaa ttctttattg attttcaaga attccacatc tgagttcatt
     6961 cgtgcgtttt tcactgagaa gcgtaaaagc tgtttacttt caaaatcgat atcatcgtca
     7021 atcacataga accgaacaaa tttagacggg ttgcaattat ctaatactga gacaaataat
     7081 gcagctaaat gtggtacgaa ttttgtgtta caacttgcga ctactgctat ttctttttta
     7141 ttcattgatc tcgcctactt tcgttagagt actgtgtgct aattttttta agtataaatt
     7201 ggtatacgga tgatctttca acgtattcca aggtttatca tgtcctgtaa agtgaacgat
     7261 cgaaggtttt tcatttcctt ctttatactg acgttcatat ttttcatttg gtgctggatg
     7321 acgttcaaaa atcagcgaag tctgcatgtt ccattttgga tgaagttgtt cccaatcttc
     7381 ataaagtaca gcattcaaag catcttggtc gtgatagatg attcgatcgc cattttcact
     7441 gaggtaatgg atagtttttt ctgtaatttc ttttttattc cattgatcaa tgtcaatcac
     7501 catcactcct gaattgaagt acaagtcatc ggaatcgatt cctaatcttt ccaaagcttt
     7561 cacttggcct ggatcgataa tagcgccgat tgtttttcca tttaacggct catcatatag
     7621 ttttacgata tcgtctagta ctaacacatc tgaatctaag taaaggactt tcttataatc
     7681 ctctttagct aataagtttg gtaaagaaat tcttaagtaa gcggtagttg tgatatggtc
     7741 actgactagg aagtcttcgt agatatcttt ttccactgtc aggaattgga tacttgcatt
     7801 acttgaatat ttatttaccg tttcttccaa tccttcttta ctatattctg atagaccatc
     7861 gtcaatcaca taaaatttta tgcgtcttgt tttattgcaa ttttctaatg cagttgcgat
     7921 catcacgctc aagtaaggag cataattttc gtctgaagca gttaccacag gaactacgcc
     7981 gtatctcttc tccatcaaaa tcactccttt ttctaatctt tttctaacct gttctacatc
     8041 tagaatattc ctcatttggt tttaaagcaa aatatatgct ttgttttcat tgaatatttt
     8101 aaaatttttt tatcacaaaa cgcatcggta agcgctaact attcgttttt catggctttt
     8161 tattcaaagg tattgaccaa aaactactat atatagccac ctttttctta agaatgtttt
     8221 ttgaaaaaat tcataatgac aaagcaagtt agtttcattt ttttaaattc tcatttaatc
     8281 ttaaggtaac aggaaaatag atatgtaaaa agaaagtagg aagataaaat gaaactagca
     8341 gcgattgatt tagacggtac cttgcttgat cgaaatggaa agataccaga agaaaatatc
     8401 caagcacttc ggaaatttga tgaaaatggc ggaatcgtaa ccgtcgctac cggaaggaac
     8461 agcatttctg ctaaagatat tttttccgaa ttaggaatcg gtggctattt gatttcttcc
     8521 aatggttcac tgattgctga aatgaaggat ggaaaaatgg cgaaagttct cagacgttca
     8581 aaaatagata gcgatacact gagaaaagcc ttcttctatg ctcaagaagc gaaaatatcc
     8641 atcattgcta gccgagaaac ccaagatgat cagctgacat tcgatgaatc aaatctagtc
     8701 aaagatgacc cttattatga acatttcaat ttacagaacc attcttttga tcaaatttta
     8761 aatatgttgg aagatccttc tcttagctat cttaaattag cattaacaga taagagtgaa
     8821 gaaaaactac agaagctaca aagagatctg caagcagatg gtatccaatc agtattctct
     8881 gatccgcatt tcttagaaat cacgcctaca ggtatcacta aagctcattc acttgttttt
     8941 ctggcggatt accttggaat cgaatcgagt gacatcatgg cttttggcga tcaagaaaac
     9001 gacattgcta tgttgaatta cagcgggttg agtattgcga tggggaatgc acagcgacaa
     9061 gtaaaagaaa ttgcaaacca agtaacactg acgaatgaag aagctggtgt tgcttatatt
     9121 ttaaaaaact tctattaaaa agaataaaat gacgatatga atgtaggagg aaagaaaatg
     9181 ttagttatta ttgatatgca aaatcatatt cttgatccaa acagcgaatt ttatattcca
     9241 gagtcagatc aattggcaga acgtattgct caaagattag ctaaagcacg ccaaaataat
     9301 gaatatattc tcttcacacg ggatatacca gttgaactga aggacaaaga agaagaacga
     9361 gaagatttgc aattgatccc tcttctttct ccacaagaaa atgaacgagt gattaaaaag
     9421 tattacttta cgattccacc tgaaacttta gctgaaatcc aggaaacttt atttgaaagc
     9481 aaagaagaac aaaaagagat cgaagtagtc gggattgaaa caaacttgtg tgtactctct
     9541 aatctgatag gcctgcagag tgcttttcct gaagcagact tttttgttga tccaatgtta
     9601 gtctccagta gaaaacacgg agaatccgct ttagagctgt tgaaagattt caacgtctct
     9661 atcgtcgaat cataaaaata tctatcttca tttacgatat ttaacacaca ataaaaaaag
     9721 cacgcagaac tgttttagtc ctacgtgctt tttctatcaa agtagattgg cttttttatg
     9781 acacagagtg aaacggcagg ctcacgacct ctttcttaaa tggtgttcaa tcagctgacc
     9841 ctcggtatta gcttaacaaa cggcaaaata tgaggaacta tttttccgtt tgttaagcta
     9901 atactcaggt caaaacgctg atttcacaac ctcttcctta aacggtattc aaaagcttgc
     9961 atctgcagta ataagaacag ccaagtaaaa acataagaag ctgtttttac ttggctgttc
    10021 ttattacttg atgcagggca gctttttcac aacctcttat gtaccttgta ggactcgaac
    10081 ctacgaccgg acggttatga gccgtctgct ctaaccaact gagctaaagg tacatcataa
    10141 ataaaattta tttttgttac ttttcaacta tagcacgaat gacaaactct cacaagtttc
    10201 aaaatataag taaaataata ttgttattct tatttctttt acttgtgtca taactatttt
    10261 gttactttaa tttttatttg cttattttag aaaaaatgtt attcttttat ttattctcaa
    10321 tgttaggagt gattattttg ccatttattg cgattttatt cgatttagtt gcggcagcag
    10381 cttattttct ccaattaaat tatcaaacct caggaattct gtttattgga atgatttttc
    10441 aaggtgtgat tacccttttg cttcttgtca tgatgctcag ctataaagga aaaagatatg
    10501 cccgtattca aacaaaagta tttgttaaat atgtttccat tcgctatggg atcatcattc
    10561 tttccttttt agtgaatgcg atcgtcctct ttttatatgt attgaattac ttagatatca
    10621 atccattgat tttttctcga tagataagac acattcagcg gaacagttcc tgcttatcag
    10681 cagaaaactg ttctgctttt tcatttttca ttgatctatt cttcttttat tttcctagca
    10741 tttcatttgt gatgtatgca ataacatgtt atcttttatt atatgaatcg ttgaggagtc
    10801 cgttacatga ttacgttggt gagagttttg ttttgggtgc ctgcggtcgc actggtcgca
    10861 agtattgttt atcttatgaa ttggaacaaa gaacggtttt atttagctat tttgactctt
    10921 ccggctatct actttatgtg gaaagttttt aattacaact actttgaacc cgatagtgtt
    10981 tttatagaag aattatcagg actggttttg tctttattga tcgtcattct ttatttgata
    11041 cgtttaaata aaaaacattg agtactattg attgcatgtg tagctttcta tagtcattat
    11101 aactattcta ctataatgaa aggtgattaa atgagtatcg aagaagctat tttactggat
    11161 actttacgtt gtcgtctgaa tttcttaaga actggccgat ctttatctca agtagctgtt
    11221 tctagcgcgt taagtattcc tttattcaaa tatcgtaagt acgaagaagg agaagaaatt
    11281 ccaagcatca ttgaattaat ctatatcgct gacttttacg atatttccgt tgattaccta
    11341 attggtcgct cagaaacagc aagcaaactg aagtgatttt ttccagcctt ggtgctggtt
    11401 ttttcattta acgtctaagg ttaacaatct atatataaag gagacatttc tatgcgatta
    11461 tggcatgaaa aattgatttc aaagcttcct cgtcaacagc ttttaggaca acatcgggaa
    11521 tgctgtgcat taagaggaaa tggctgggga aagaaacatg ctactgtgga ttatgttttt
    11581 cactattctc cttatagatt attccaatat catcagcttg tcatggatga aatggaaaaa
    11641 cgtggttaca gcccagcacc agagtggaaa aatcctatgt atcgtggcaa atcatgcgaa
    11701 gcattttttg atttacctac tgtagagcgc aacgtgccga tttatccgga acacgatgaa
    11761 gtttatctag cagaatgttt agcaaatttg gagcaaaaag gaatttatct tacctaatat
    11821 aactagaaaa gccttctatc tcctcttact tcattaaaaa gctttaacca tcttagatca
    11881 agctaaaatg tcgtaagttt tagggttatc ttcatcctca cgtgcaaaac taaaagcgta
    11941 ctctagtttt ggttcatcgc caacttccct agacataaat gaacatctcc tgacgtggtt
    12001 taaaagtacc gcatcttcga cgtctgtata cgatgcacag cacagattgc ttcttttgat
    12061 ctttcttttg atttttctgt tgcttcttct acaccttctt cgattactac atcgatgctt
    12121 acaattgctt ctgcctaata ttcccatgca tcgtcgattt aagcctctgt agtcactgtg
    12181 atcgtttcca cattttaact cctctgtcgt ggcttcagtt gattttgtga tcagttcagt
    12241 tgctaagcca gagtcagaac aacctgccat tgctagcgtt aatattgata gtaaaaatag
    12301 tttttttatc ataaggttcc ccccctgaaa atagactaaa ataataacgc tttctttttt
    12361 tgttttcaga cgaaaattaa taatttctaa atattcttta aaaaagctta taactattat
    12421 gcctttttta atatataaca cagttatttt taaaaataag aatgctaaat cactctacaa
    12481 taacggcgaa agcacaaaaa ataaaaaaat tattacgtta ttaaaaaaac agatgaaaga
    12541 tcaggtttta ttagatctca ttctttcatc acttgaaggg atttaatgaa ctactttttc
    12601 ctctttgtcg tttttatata ttcgtattcc ttcaaacagt aggatagcct ctttcaatgc
    12661 ttgatatttg aactgtccgt tacttaaaaa tttagatgtg ccgccctctt cctagaacat
    12721 attctttttt actttttcat taattgacag accaatcgaa cgaaactgta aatttcgata
    12781 ggataatgat tggtcaaact cattcatttt caagacatct cgattcatat tcaagatagg
    12841 aatcttttta tcaacatcac tttattcgta ttttcctcta ccataaaagc ttcacgctcc
    12901 acaaaattgt tttatacact actattcagc ccattcaacg accaatgaat t
//
LOCUS       DAXLPC010000073        12856 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.073, whole genome shotgun sequence.
ACCESSION   DAXLPC010000073 DAXLPC010000000
VERSION     DAXLPC010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.073"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            135..3524
                     /locus_tag="ACF3UE_002063"
     CDS             135..3524
                     /locus_tag="ACF3UE_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFD3635443.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            3527..4948
                     /locus_tag="ACF3UE_002064"
     CDS             3527..4948
                     /locus_tag="ACF3UE_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFD3635444.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            4945..6822
                     /locus_tag="ACF3UE_002065"
     CDS             4945..6822
                     /locus_tag="ACF3UE_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFD3635445.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            6914..7756
                     /locus_tag="ACF3UE_002066"
     CDS             6914..7756
                     /locus_tag="ACF3UE_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFD3635446.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(7908..8783)
                     /locus_tag="ACF3UE_002067"
     CDS             complement(7908..8783)
                     /locus_tag="ACF3UE_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3635447.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            8990..10021
                     /locus_tag="ACF3UE_002068"
     CDS             8990..10021
                     /locus_tag="ACF3UE_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFD3635448.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            10110..10415
                     /locus_tag="ACF3UE_002069"
     CDS             10110..10415
                     /locus_tag="ACF3UE_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFD3635449.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            10594..12609
                     /locus_tag="ACF3UE_002070"
     CDS             10594..12609
                     /locus_tag="ACF3UE_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFD3635450.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            12611..>12856
                     /locus_tag="ACF3UE_002071"
     CDS             12611..>12856
                     /locus_tag="ACF3UE_002071"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3635451.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEE"
BASE COUNT         4537 a         2381 c         2468 g         3470 t
ORIGIN      
        1 ttggtgtgat tccctttagc gcccttcgta taataattat catattaaaa taaataaaat
       61 tatgtaacgc ctgtttattt taataatttt cactattcac gtcaaaacag aaaaaaagaa
      121 aaaggagggg aaaaatgacg accacaggga agaaactgaa agttattttc atgctgataa
      181 tattgagttt atcaaacttt gtgccattat ctgcaatagc agacactaca gatgatccaa
      241 cagttttaga aacaatttca gctgaagtca tttcggatca gtctggaaaa aaagcactga
      301 acatcaagct aaatgcgaat aacaccagtg ctgaaaagat agaaaaagaa attggtctag
      361 tcgaaaatta cttaagtgat gtggaaagaa aagaaggaga tggctatgct tatcaggtaa
      421 atagcgggaa aattacgttg gaaatctcat caaacactaa acaaactatc gatctgagtt
      481 ttccaatcga tccagcactt taccacagcc aggcaaacaa gctgatcgtc gataataaag
      541 aatatgacat tattgatgag acagaaaata agaaagatac agatgtgtca gtaccaaagc
      601 cagacgaaat agaagaagaa tcatcaaaag aaaacgaaaa ttctgtcagc ccatttacat
      661 tgcctacatt atccttgcca gctgtgagtg tgccatctaa tcaaacgatt cctacagaat
      721 atacaacaga tgatcagggc acttatccta aagccagttg gcaacctaca ggaaatacaa
      781 atgttcttga tcatcaaggc aataaaaacg gaacaaatca atgggatggt ataaattctt
      841 ggaatggaga tcctaatgat cggacccatt cgtatatcga atatggagga accggtaatc
      901 aagcagacta tgcgatacga aagtatgcaa aggaaacaag tacacccgga ttgtttgatg
      961 tttatttgaa tgctcgtgga aatgtacaaa aagatatcac gcctcttgat ctcgtattgg
     1021 tcgtagactg gtcaggaagt atgaacgaca ataatcggat cggtgaagta aagattggtg
     1081 tcgatcgttt tgtcgatact ttagcagata gcggtatcac agacaaaatc aatatgggat
     1141 atgtcggcta ctcaagcgaa ggatatagct acagtaacgg tgcagtacag atgggttcat
     1201 ttgattcagt gaaaaatcaa gtaaaatcca ttacaccttc acggacaaat ggtggtactt
     1261 ttacacaaaa agcactaaga gatgcaggaa gcatgctatc cgttccaaat ggacataaaa
     1321 aagtgatcgt tttgctgacg gatggtgtac caacattttc ctataaagta cagcgggtac
     1381 acgcacaatc aagcagcaat tattacggaa ctcagttttc taatacgcaa gatcggccgg
     1441 gaaatacttc tctaatctca agaatctatg atgcacctga ccaaaacaat ctatccagaa
     1501 gaatcgacag tacgtttatc gcaaccatcg gagaagcgat ggcactcaaa gaacgaggaa
     1561 tcgaaataca tggtcttggc atccaacttc aaagcgatcc ggcagctggt ctctcaaaag
     1621 cagaagtaga gtctcgtatg cgacaaatgg tttcatcaga tgaaaaaggc gatctttact
     1681 atgaatcagc tgatcatgca acagatatct ctgaatacct agccaaaaaa gctgtacaga
     1741 tctcagcaac tgtaagcaat ggacaaataa atgatccaat cgcagaacca ttcatttatc
     1801 agcctggtac actttcagtc aagagtgtgg ggacaagtcc tacaacggtc actccatcta
     1861 tttccataga aggaaatacc atcaagagca atcagatcta tttaggaaaa gaccaagaaa
     1921 tccaaatcca ttaccaagtg agaatccaaa cagaaaatga ggacttccat ccaaatttct
     1981 ggtatcaaat gaacggcagg acaactttcc agccaaacat tgataccaat gaattagctg
     2041 aattcggtat accatctgct aaagctcccg gagtcagtct tcacatcaaa aagttatggg
     2101 aagaatttga caacaatcta gctgatcgtc cagatcaagt tacttttgag attcaacggg
     2161 aacatacgac aaatgctgca gcttggaaaa acggatatat tcgaatcatt aaaccagcta
     2221 aagatacaac aaatacgtgg gaacgtgcag acattgacaa attatctgca aatagcggag
     2281 aaagttatca agagatatta tcactacctc aatacaataa tcaaggtcaa gcattcagtt
     2341 accaaacaat caaagaatta cctgtaccag gatacgattc tcaacaaata gatgcaatga
     2401 catggaaaaa tactaaacaa ttcacaccgt taaacttgaa aataacgaaa aattcctcta
     2461 caggtgaaaa ggatcttatt ggcgctgttt tcaaattaac aggagattct attgatactt
     2521 tactaacaga tcatggcgac ggaacctatt ctcttccaga aaatgtcaaa ttgcaaaaag
     2581 aaatgaccta tacgctgaca gaaacaaaag ctccagaagg gcatggatta agcaaaaaga
     2641 ctacttggga aatcaagatc gcttctgatg gtacggtaac cattgatgga aaaacagtca
     2701 ctacttccga tgatacgatc cagttgacta ttgaaaatcc ttttgttgaa gttcctgtag
     2761 cagtacgtaa gtatgcgatg caagggacgg acaaagagat aaatcttaaa ggagcagcat
     2821 tttccctaca gaaaaaagaa gcaaatggta cttatcagcc aattgacagc caaacaacga
     2881 atgaaaaagg tcttgccagt tttgattcac tcacacctgg taaatatcga gtcgttgaaa
     2941 cagctggtcc tgccggatat gatacttcgc cgggaaatta tgaattccaa atcgataaat
     3001 atggaaaaat catttacacg ggaaaaaata ccgagatgac aaataatgta tggacgctca
     3061 ctcatcaaaa tcgactaaaa gcgtttgatc taacggtaca caaaaaagaa gacaacggac
     3121 agacattaaa aggagcaaaa ttcagactgc agggaccaga aatggactta gaatcgccaa
     3181 aagatggaca agaaacagat acctttctat tcgaaaattt aaaacctgga acttatacgc
     3241 tgaccgaaac ttttacacca gaaggatacc aaggtctaaa agagccagtt actatagtta
     3301 tacacgaaga tgggtcaatt caagtggatg gacaagatca tgaatctgtt ctgtcaccag
     3361 gagccaaaaa caaccagatt tctttagaca tcacgaatca ggcaaaagta ccattacctg
     3421 aaacgggagg aattggccgt ttaggaatct atctagtagg gatgattggt tgtgcgtttt
     3481 ctatttggta tctttttttg aaaaaagaaa gagggggcag ctaaatatga aaaaacttgg
     3541 ttggcttagt atgtgtctct tcttgttact atttaaacca gcttttactc aggtagcaac
     3601 agaaacagaa acagaaatgg ttcagattac tttacacaaa ttgcttttcc caaacgggca
     3661 actgccgaaa aatcatccaa atgacggaca agaaaaagct ttattacaaa cgtatcgagg
     3721 attaaatggt gtcacattcc aagtttatga tgtcacagat tctttttacc atctacggga
     3781 aaagggcaaa acggtagaag aagcacaagc agagatcgca aaaaacggtg cgtcttccgg
     3841 tatgtttacc gcagaagcaa caactacaac tcttaacaac gaagatggta tcgcttcttt
     3901 ttctctggcc gctaaagatc aagaaaaaag agataaagcg tatcttttca ttgaatccaa
     3961 agtaccagaa gtcgtcaaag aaaaggcaga gaatatggta gttgttcttc ctgtacatgg
     4021 acaaaacaat caaaaacttt caactatcca tttgtatcct aaaaatgaag aaaacgacta
     4081 ccctgatcca ccttttgaga aggtattaga agagcctaga aatgatttta cgattggtga
     4141 aaaaatcact tattccttgc atacgacaat tcctgtaaat atccttgact atcaaaagtt
     4201 cgaattgtca gatagtgcgg atgaagcatt aacgttttta cctaatagtt taacgatttc
     4261 atcgaatgga gaaaagctga cagaaggctt tgtcatacac aagaaacctc acggatttga
     4321 tgttttattt tcgatccctt cgttggaaaa atatgctgga aaaaaactga ccatttctta
     4381 tcagatgcag ctaagcagta cagcacaggc gaacaaggaa atcaacaaca acggaacact
     4441 ggattttggt tttggtgtca gtacaaagaa agtctctgta tatacaggga gtaagcaatt
     4501 tgtcaaaatc gagacaaata aaccagataa acgattagct ggcgcagtat tccttattaa
     4561 aaacaaagca ggaaattacc tccagcaaac agccaacgga tacaagtgga caaagaacga
     4621 atcagatgcg cttcacctga tttccgataa aaatggcgct ttttcaattt ccgggttgaa
     4681 aacaggaagt tatcgattaa aagagatcga agcaccttct ggttatattt taagtgaaac
     4741 agaaattccg tttaccattt caacttttct ttctgaggat aaagaggcgg acagtatatt
     4801 gaaagtagtc aataaaaaag aaaatagccg tccatttctt ccaaaaacaa acgaaacgaa
     4861 aaatacactt ttaggcgttg ttggtatggt attcgcaagc tttgcaatct ggttgtttat
     4921 caaaaaaaga acaggagtga aaaaatgaaa aatcataaaa aaataaacgt tatgttagga
     4981 gtccttttcc ttattttacc attactcaca aacagcttcg gcgcaaaaaa agtgtttgca
     5041 gaggagacag cagctcaagt catccttcat aaaaagaaaa tgactgattt acccgatcct
     5101 ttaatccaaa acagcgggaa agaaatgagc gaattcgatc aataccaagg attagccgat
     5161 atttcatttt cagtttataa cgtcactcaa gaattttatg cgcaacgaga taaaggagcg
     5221 tccgtggatg cagcaaaaca agcagtccag tctttgactc ctggtacacc agttgcttca
     5281 ggaacgacag atgctgatgg aaatgtcact ttatctttac ctaaaaaaca aaatgggaaa
     5341 gatgcagtct acacgatcaa agaagaacca aaagacggag tgtcagctgc cgcaaacatg
     5401 gttttagctt tccctgtata tgagatgatc aaacaagcag atggctctta taaatacggg
     5461 acagaagaac tagatactat ccatctctac cctaaaaata cagtcggtaa tgatggaacg
     5521 ttgaaagtta caaaaatcgg tactgccgaa aacgaagcac taaatggagc agaatttatt
     5581 atttctaaag aagaaggaac accaagcgtc aaaaaataca tccaaagtgt cacagatgga
     5641 ttgtacactt ggacaactga tcaaaccaaa gccaaacatt tcattactgg tcattcttat
     5701 gacatcggca acaatgactt tgccgaggca tctattgaaa aaggccagtt gatcgttaat
     5761 catttagaag ttggaaaata taatttagaa gaagtaaaag ctcctgataa tgcggaaatg
     5821 attgaaaagc aaacaatcac gccttttgag atcctggcaa atagccaaac accagtagaa
     5881 aagaccatca aaaatgatac gtctaaagtt gataaaacaa cacctcaatt gaatggaaaa
     5941 gatgtcgcaa tcggtgaaaa aattcaatat gagatttctg tcaatatccc attaggtatc
     6001 gctgataaag aaggaacgca aaacaagtac acaacattca aacttatcga tactcatgac
     6061 gctgctttaa catttgataa tgattcttca ggaacgtatg cttatgcctt atatgatgga
     6121 aataaagaaa tcgacccagt aaattattct gtcactgagc aaacagacgg attcacggtt
     6181 tcagttgatc cgaattatat tccttcatta actcctggcg gtacattgaa attcgtttac
     6241 tatatgcatt tgaacgaaaa agcagatcca accaaaggat tttctaacca agcaaatgtc
     6301 gataacgggc atacaaatga tcaaacacca ccgtcagtcg atgtcgttac tgggggcaaa
     6361 cgatttgtta aagtagatgg tgacgttaca tcagaccaaa cacttgctgg agcagaattc
     6421 gtcgttcgtg atcaagatag tgacacagcg aaatatttat cgatcgaccc atccacaaaa
     6481 gccgtcagct gggtatcggc gaaagaatca gcaacggttt ttacaaccac aagtaacggt
     6541 ttaatcgatg tgacaggtct aaaatatggc acgtactatc tggaagaaac gaaagcgcca
     6601 gaaaaatatg ttccattaac aaaccgtgta gcatttacta tcgatgaaca atcttatgta
     6661 acagcaggac agttgatttc tcctgaaaaa ataccaaata aacacaaagg tacacttcct
     6721 tcaacaggcg gtaagggaat ctatgtgtat atcggtgcag gagtagtcct tctactgatt
     6781 gctggactgt actttgctag acgcaagcac agtcagattt agtctttttg caagaattgg
     6841 aaaaaggagc agcggattac gcaaatgctc ctttttcttt tattatcaaa cagtcatcac
     6901 aaggagaaca caaatgaaac caaagaaaag gaaacttcta gatctgctga tgcttttctt
     6961 gcttctctca ggaataggga tactagctta tccatttgtt agcgacgcgc tgaataatta
     7021 tctggatcag cagatcatct ctcattatca gcaacaagcg gtcaaagaaa atgaagaagt
     7081 catggctaaa atccaagaaa acatgacaaa gaaaaaccag caattagcaa aagaaggtgg
     7141 aaatccaggt gcagatccct ttactaagaa aaaagaacct gcgaaaaagg atagaaccta
     7201 ttttgagaaa catacgatcg gtattttgac gatccctgag atcaatgtcc atttgccaat
     7261 ttttgatgaa acgaatactg tgctgctaga aaaaggtgcc tcattattgg aaggaacgtc
     7321 ttatcctacg gggggagaaa atacacatgc cgttatttcc agccatcgag gactgcctca
     7381 agcaaagttg ttcacagact taccgaaact gactttaggt gattctttct atatcgaaat
     7441 caatggacgg acactcgctt atcaagtcga tcagatcaag acggtagaac cgactgatac
     7501 aaaagatctg agaatcgaaa aagggcagga tttcgtgaca ctcctaactt gtacacctta
     7561 tatggtcaac agtcatcgct tacttgtcag agggcaccgg gttccttatc atgcaaaaga
     7621 agttcaaaaa gaagtacaga aagtatccga gaacaaacga tttttcctgt atggattgtt
     7681 agctgcatgt atactgattt tcctccttct tatatatctt tttcgtcaat cgttcaaaat
     7741 aagaaacaga agttagctat tcctcatttc tataatatat ctattcgaat cgttccgtaa
     7801 acaaacaggc tgaggtttga aaaagaaaac ttcagcctgt ttttatgatg atatcaaaga
     7861 gagcctatca aacactatct ttcttattac taaatgagga tcttttctta agttttccga
     7921 tattctttaa gaaggccttt ttgcatcaat tcttgtttgt ttttcaagtt gcggatattc
     7981 tcttcaaaat tttgagaata tatcactgag aataacgtat ttaatacgta atcgaaggca
     8041 atttgagagg agaaagtcgc tactttagca aaatcatatt cctcctgcga tataacaaga
     8101 cacatatcag cctgtttggc catttctgaa tgctgatttc cggtaatcag caaggtaggg
     8161 gcctctacat gcttcaaata ggtcattatt cgttcataat gatggatgcg accgctgtag
     8221 ctaataaaaa tggcgcaatc ctcgctagtc aaattggctg cattccaaga agaatcactg
     8281 tattcttcag ccatgatcaa aaacttattc aacttgacca ttttattctg gaatttcctt
     8341 gccgtgattt gagaatcacc ttttgcaaaa agaaagattc gctgtgcctt gttcaatact
     8401 ttaccgattt gatctaaatc ttcatgttca atctgcaatt gtgctttttt tattgactgg
     8461 atcgataaat ccgccatttt ctttgcaatt tgctgagtgc tatcttcact tgaaaaagga
     8521 aaattaggat caatcgtttg attgaactga gcaatcaatt gatgaacttc ccgccccagc
     8581 tcgaaacgga attctttaaa tccgctgaat cccatttttt tgcataaacg aatgatagct
     8641 gaatgggaag tatacgtagc ttttgctaat tcttcaatcg tcatgtagac tgcagcttcg
     8701 atattcctac ggatgtaatc gacaatccgt ttctctgtcg tggtaaacaa ctcttgtttt
     8761 gttagttttt cttcaataag catgatctga cctccaaatt ctatcttact gataaacact
     8821 tggttccgct actatctttt tgatttttat ccttactttg aacattaatt tcaccaaacc
     8881 gaatgataac aagtgttttt ctgaactttt ttaccagaat agctattata aatactttct
     8941 gcgcttttct aggatatact gaaaacatca ataaaaggag gcaccactca tgcttacaat
     9001 cgcttatctt ggcaatggaa agagtacaaa tcgctatcat ttgccttttt caagaaaact
     9061 tacgaacaaa atcaatatca aaaaaatttt ttccccatct gaaccagtgt ggaaaacatt
     9121 cgaagacatc gaatatactg atcagctgtc tgatctttgg gatgatcctg agatccaatt
     9181 agttgtcatc actacaccta gtcaatttca ttatgaatat ggaaaaatgg cactcgaaca
     9241 tggtaagaat gtactagtag agaaaccttt tgcagaaacg tcaaaggaag cagaagagtt
     9301 atttgcatta gcaaaagaaa aaggtctatt tatccaatgt taccaaaaca gacggttcga
     9361 ttctgacttc ttgacagtcc aaaaagtaat cgaaagcgga aaattagggg atattttaga
     9421 agtagaaatg cattatgatt atttcagacc ggaagtacca gaaaatacgc atgaattttc
     9481 tactgcgaac agctatttat atggacatgc ttgtcataca gtagatcaag ttctttctta
     9541 tttcggcgaa ccagatgata tcagctatga tgtacgtcaa cttttaggga aaggacgaat
     9601 gaatgattac ttcgatctgg attttttcta tggaaatatg aaaatttcga taaaatccag
     9661 ttatttccgc atcaaagaac gtccaagttt cgtcgtttac ggaaaaaaag ggatgttcgt
     9721 gaaacaaaca aaagatcgac aagaagaaca tctgaaaatg ttttacatgc ctgatcatga
     9781 agactttggt atcgatttgc ccgaacatta tggtgtattg acctatatag atgaacaagg
     9841 gagttatcat gaagaaaaag taatttccga ggttggtgat tacagccgtg tctacgaagg
     9901 gatttacgag acattagtta atggcgcaga aaaagtcatc aaagatgaag aaacaatctt
     9961 acaaatgaaa attttggaag aaggaatcaa aagcattcaa gaatcagaag gaaaaatatg
    10021 acatatttgt aagaatcggg tttgtttttt gacgcataaa ctgtcttatt gtacgatgaa
    10081 aaagtataga actactagga ggaaccaaca tgacaaatta tgacggtgaa aaacacaaac
    10141 gattaagagg ttcaatggcc cctaaaacag aagaagaagt ggctttagca ggaactaatt
    10201 ctggtgaaac agaagacaaa gaagaatcat tagctggcac aaactctggt gaaacagaaa
    10261 ataaagaaac agctttatct ggttcaaatt ctgtagaaga ggaaacaaag cctaatgagc
    10321 ccaatcactt tgaaaaagat atcgaaaaag cggttgaaga tgtcaaagaa aaatttgaag
    10381 aactgacctc aaaaaataaa catgatcatc attgatcgga cgaaatcaat tcataaaagc
    10441 aggagacatt tggtcacctg ctttttttct gtatccattc gatagaaatc gttcggtaca
    10501 gtcgtaaaaa aaatccaact gtaagttgta ccaaacaccc ctcgatttaa aagcgctacc
    10561 atactagaat ataagtagga ggtgaacagc gctgtgaact acaaaattag ttatctcctg
    10621 aaaacaccaa gagaaatcag tctagaaaaa gcagcagaga tcatcgaagt aaatacaagc
    10681 gaggcgatca aacaattaac tccttttgcc gaatatgtgg atgatacccg tatccgtata
    10741 aagaaattcc gagcaatcga ctgggcagaa aaatttttgg atattactcg atttgaagct
    10801 gtgtataccg aacaagagcg aagagatctt ctttatttga tggtttattc gactgcaacg
    10861 tctgtttctg tttttcattt tcaagatttt cttcaggttt ctaaagggac agtcctgtca
    10921 gatatcaaaa agataagaaa tgaattagaa gtggaagatt gtcagctgtc gtatactagg
    10981 aaaactggtt ttaggctgct agggtcagaa gcaatattaa gaagagaagc aaaaaatcgc
    11041 actgctcgtt tgatgcagtc acttgctgga agatttgggc tcacgtattt aaccgcaacc
    11101 ctttccattg attattacgc caaagttaga gatttgctag ataaaacgat ttcactatca
    11161 gatcttcgat tcgcaccaaa tcgaatggat gaattagctt attatttgag tttgacaacc
    11221 attcgaattg gaaaaacatc catggaactg gtaaaagatg ctgaactgtt ggcttctctt
    11281 gcagtcactg acattagtcg acaagtattg actggccttg gctattccga acatcaaaat
    11341 tcggagatta tatttttctc tctttgctta gcatcgatcg ttgaaggaga tgtccaggag
    11401 cctgcacttg attttttgct ggaatgttct tcagaagtca tccatcgcat ggaattcctg
    11461 atggccgtag aatttgcttc gtttcgtgaa ttattgatga atgtctttta tcacttggtc
    11521 cctgcctatt ttcgtatttc ctattctttt tatttaccta atgtgatgat cgatcaaatt
    11581 aagcatcaat atgcttccat ctacgaaatg acaagaaaag cattacttcc gttagaaaga
    11641 cgaataggga agagcatccc tgaagaagag attggttttt tcactatact atttggcgga
    11701 gagatcagaa aagcggacgc agaagaaaga aatagaaaaa taagagccgt gatcgtctgt
    11761 ccaagtggca ttagctcttc attgatctta aaaagtgaac ttcagcaatt attcccgatg
    11821 atctttttta cagagactaa ttcagctgac cgcttacacg aggttgacga aacttcttac
    11881 gatattattt tttctactgt acctctcaca cttactgata agaaaaagtc tctctatgtt
    11941 ctgcatccaa tcatgactga cttggaaaaa aatcagctga tcaatcaagt acaaagagat
    12001 tggctgatac caggattttc aatgccttct gcccaagaat tgttgtcggc gctactgcct
    12061 tatatcgaat taaaagaagg cgtagacgaa gaaaagctct atcaagtatt aaatcgtaaa
    12121 atgaacaaac ttttagaaaa gaaggaggat caacgtccta tgctatctga attattaaca
    12181 gaagaaatga tccaattatc ggatcaacca aaaaactggc aagaagcaat cacatttgcc
    12241 gcacagccgc tattatcaga aaataaaata gaagaaagtt atatcaaagc tatgatcgag
    12301 cgcgtggagc agtatggtgc gtttatccat attggcgatc acatcgcatt acctcatgct
    12361 cgtccagaag atggcgtaaa cgaagtaggg atgtctttgc tgaaacttca acaacctgtg
    12421 gatctgcttg ataatccagc ccatcccatt agtttgttca tctgtttagc tgctatcgat
    12481 aatgaggcac atcttcgggc tttggcaaat ttaacaaagc tactttctaa taaacaaaat
    12541 cttcaagatt tattacacgc atcaacaaaa gaagaaatat tagcgatcat aagaaaagga
    12601 gacgaatgat atgaaaattt ttgcagtatg tcaaagtgga ttaggaacaa gttttatggt
    12661 agagatgaac atcaaacaag cacttgcaga tcttggagca gatgtggacg agtttgaagt
    12721 aagtcatacg gatgttggaa gtgtatctag cgatatggct gattatttct tcattgagca
    12781 ttctttgaaa gatacgctaa cttctatacc tgatgaaaag ctcgtacctt tgcaatcgat
    12841 cattgacagc gaagaa
//
LOCUS       DAXLPC010000074        12823 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.074, whole genome shotgun sequence.
ACCESSION   DAXLPC010000074 DAXLPC010000000
VERSION     DAXLPC010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.074"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            131..3658
                     /locus_tag="ACF3UE_002072"
     CDS             131..3658
                     /locus_tag="ACF3UE_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFD3635452.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3655..7377
                     /gene="addA"
                     /locus_tag="ACF3UE_002073"
     CDS             3655..7377
                     /gene="addA"
                     /locus_tag="ACF3UE_002073"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFD3635453.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7446..7787
                     /locus_tag="ACF3UE_002074"
     CDS             7446..7787
                     /locus_tag="ACF3UE_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFD3635454.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8096..9139
                     /gene="pheS"
                     /locus_tag="ACF3UE_002075"
     CDS             8096..9139
                     /gene="pheS"
                     /locus_tag="ACF3UE_002075"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFD3635455.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIVRKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9144..11564
                     /gene="pheT"
                     /locus_tag="ACF3UE_002076"
     CDS             9144..11564
                     /gene="pheT"
                     /locus_tag="ACF3UE_002076"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFD3635456.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="ACF3UE_002077"
     CDS             complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="ACF3UE_002077"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFD3635457.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
BASE COUNT         4338 a         2238 c         2721 g         3526 t
ORIGIN      
        1 tttgcgtata cttaaaaaag tagaaatatc agaaccttaa aaggatataa tttgaagaat
       61 atagaacaaa tgttcagtat tttttgatat aataaaggag caccgtatca tgtgttgaag
      121 gaggaaaagc atgtctttac aatttattct tggaaacggg aaaaaagatc accgtcaagt
      181 cttgatcgac gaagcatccg cttggctcga ccaggatgca agtaaccaag tatttttcct
      241 tgttcccaac tacagcaaat tcgaacagga acaagaaatt ttagcggaga tgcgaagaag
      301 aagcggaaaa aaaactttca gcacaacaaa cgttcaagta tttagttttt atcgtctggc
      361 ttggtatttg ctgcaacaga caactcttct tacaggaaat gaattatcag aatcaggatc
      421 tgcaatgatc ttgcgacaga ttttagaaaa aaatgaggaa gaattaacaa tctttcgcgg
      481 agaaatcaat aaaagagggt ttattcgtca attacaagaa ctctacagtg aattgcgtac
      541 aggaaatatt caaccagaag acctgatgct tttatttggt gattcaccta atgcagaaga
      601 ccagcaactt aaaatgaaag acttgaagct gattttttca gcttatgaca gcgaattgac
      661 tcaacgtgca ctaacaaatg aagatgcact atctatacta gcaaattata tgcagacaca
      721 agatttcaac aacgtcaaat ttattgtcag tggtttttct cgaatcaatg gtcaagagta
      781 tcaattactg caggcaatga tggaaaaggg gcaattggtt gtcgatttat tgctggatcg
      841 tccttataca gcggatcttc cagaagtact tacgctcttt catgagactg gaaagcttta
      901 tttccgtctt tttcaaagtg caagagaacg gaaagtccct atattagtgg accgatttgc
      961 accagagcag actcgtccga cagagcttca actgctgcaa acaatgtggg aagagacatc
     1021 tagccaaaag aaagcggcag tacacaaaat agggggacaa gagcatctcc atttgtggga
     1081 agctgaaaat ccaactgaag aagtccgaca attagctgtt gaaatcagac gactagtcag
     1141 tgaagaaaac taccgttatc gtgatatcca agtgctgaca aaaaatatgt ctttatatgg
     1201 aaatatcctt cggccgatct ttcaagaaat ggcaattcct ttttatatcg atgaagaaca
     1261 aatgatggaa aatcatccgc tgatcgaatg gatcaacagt ctgttcgctc ttgaccgcta
     1321 ttcttatcgg ctaagtgata ttatgcgttt tttcaaaact gaattatttc tgtcgacgga
     1381 agcagaaacc gaacttgatg aatggaaaca agagcgagat gaattcagga aaaaactgga
     1441 catcactgaa aatgtagcac ttgcttacaa ttatcaagga acttattgga ctcgtgaaaa
     1501 agactggcag tttgtggcgt atgattttga agcagaacag attgaagacg tacagtattt
     1561 ggaagaacag tcaaatacga ttagacgatt atttcagaaa gctgtaccag tatttttgaa
     1621 aaaaataaag aaaagcaaaa caggacaaga ggccgcaaat gttttttatc aatttttgat
     1681 ccaaagtggc gtacagcaac aattattgtt ttggcgtaat caggaagtag acagaggaaa
     1741 cttagaagcg gcaagaaacc atgagcagac atggggagcg ctgattgatc tgttggatga
     1801 atatgtagta atttatggtg aatcggcttt tgactggtca ctgttccaag aaatcattac
     1861 aagtggtcta gaaaatctaa gttatggtaa aatccctacc gcaatcgacc aagtgcgaat
     1921 caatcgtttg gaattagttc gaccaaatca agctgccgtc acttttgcat tagggttgaa
     1981 tgatcaagtg tttccagacc gaaaagagac aaaaggattg ttgtccagtg aagaacgaga
     2041 agtattaaat caggccttgc cagatggaca gtttttattc gacccatcaa aggaaagtat
     2101 ctcttttgag cctttccaag cctatcttgt ttttctttcc ggaacagatc gattatatct
     2161 tagttatgca caaagctatg acacagatgg ttcgctgaag atgtctcctt atttgcgtag
     2221 aatcacagaa tatttatctg ttcccgtcga gagaaaagag catttgacga tcgaaagcga
     2281 ccctaattgt tatgtaggga cttacagaag cggaatcaat acagtcaata ggatttatcg
     2341 attagcttta gatgaaaaaa aacctgtacc aaagcactgg caaaagctca aagaattagt
     2401 actgaattcg tcatggcgaa attttgcttt acagattttt gaaagtcagg aacatttaaa
     2461 tgttcctgtt tcgatgccag aaaaaatggc ggaagagctt tatggaaaag agatttatac
     2521 ttcaatttca cgtatggaga atttttataa ttgtgaatac aaatacttca tgcaatttgg
     2581 tttgaaattg aaagaacgaa ctgtttatgg tctaactcca gcagcaactg gtgattttta
     2641 tcatgaatca ttggatcgtt tcttcaagct actgttttca aaccaattat ccttagtgaa
     2701 tatgtccgat gcgcagcgta gagactttac tgaaaaagtg ctgcaggaag tattcggaga
     2761 acttcggttt gagatattgg atagttctgc aagaatgaac tatatccgct accagttagg
     2821 acagacgatt caaaaagtga catgggcttt gcaaaaacag agcaaaaata caggcatgca
     2881 tcctcttcag acagagattc tatttggtca gattgctgga gcaaaaggta tcacaggtct
     2941 ggaattaccg ttgagtaatg gtggaaaact ccatgttcga gggaaaatcg atcgaatcga
     3001 tgtagcttct gaacaagaag atacttggct aagcgtcgtt gattacaaat ctagcggacg
     3061 ttcattcgat gtcacagaag cttattatgg catggctatg caattattga cgtatctgga
     3121 cgtagcattg atggatgcgg tacgtttgac tggaaaggcg gctgttaaac cagcaggatc
     3181 atattattta catgttcata atcctgtatt gacggagaca gatgatgtag agaagaatac
     3241 attgaaaaaa tttagttatg atggcgtttt tgtcgatgat cccgctcttt tagaagtact
     3301 agatcattca ctggaagcaa aagaacaatc actgatctat ccagtgaaaa aaaatgcgaa
     3361 agatgaatac caaaaaggta gtttcagtaa agacaaattt ttcacggaag aagaactgca
     3421 actattcatg gcgcataatc gggaaaatat gcggttagct ggagatgcga ttacttccgg
     3481 agaaatcaaa ctaaatccag cttataaaga taaacagcgg attgcctgcg aattttgtcc
     3541 attcagaagc atctgtacgt ttgatgtgat gctgaaagaa aataattacc accgtctgga
     3601 gaaaatagat aaggaagaag cactgcgtag aatattgaaa aggagtgaag aagagtgaat
     3661 caaattcctt taaaaccgca aaatgaacga ttcacagatg atcagtggca agcgattttt
     3721 gatcaaggag ataatctatt agtctctgcg tctgccggat caggtaaaac tacagtgctt
     3781 gttcgaagag tgattgaaaa actaaaaatg ggttttgata tcgatgaatt attgattgtg
     3841 acatttactg aagctgccgc aagagaaatg aaagaaagaa ttcaagaggc attacaagaa
     3901 tccgtcaata gcgaaagtga ccctgtacgt agacagcatt ttactaagca gttagtttta
     3961 ttgcccacag cgaatatctc aaccttacat gctttttgcc tgacagttat tcgacgttat
     4021 tattacttaa ttgatattga tccagtcttt cgcatgttaa cagatgaaac agaaacgatc
     4081 ttgatgaagg aggatgtgtg ggacgagctg agagaagcac tttatgcaga aaatgatgaa
     4141 cgatttttcc aattaacaat gaatttttct aatgatcgtt cagatgacgg cttgacgaat
     4201 ctggtgtttt ctctttatga gtttgcccgt gccaaccctg acccccaaaa atggctagaa
     4261 cagttaagcg ataattatcg tttgcctgag gggctagcga aatctcgatt atatcaaaaa
     4321 caaatccgtc ctttagtttt ggcagatata taccaatgtg tacagttata tgaacagatg
     4381 actcagttag cacaaggtga aggattagaa aaaatgcatg agcaagtagc tggagaacaa
     4441 cagcagatca agaatatcta tgaagcgttc tcgcaagatc ggttagaaga agcttatgct
     4501 ggtttggaac aactaacttt ttcaactttt aagagcagtc ggaaagcaga attgaaagaa
     4561 atttccaatg aagtcaaggg catgagggat aaagcaaaaa aactgattca gcagataagt
     4621 aaaagttatt ttcctgtttc cccaagccaa atggaagaat taacggacaa agcactaccg
     4681 ttagtcgaag aaatgacaaa agtcacgcaa agcttcatgg acggtttcag tatgcgtaaa
     4741 cgggaaaaag gtgtgctgga tttcaatgat ctggaacatt tagcgttgca gattctcaca
     4801 gaaaaaacga aagatgtatg gctgccaagt gaagcttcaa aacattatcg aaaaaaattc
     4861 aaagaagtaa tggtagatga atatcaagac gtgaaccaat tacaagaagc cattttatac
     4921 tggctaagag aacccgatga tacaaaagga aatatgttca tggttgggga tgtcaaacaa
     4981 tccatctatt ctttccgttt agcagatcct agtttattta tcgggaaata cgagaatttc
     5041 tcaaagaaag aaggcggacg tcgaatcgtt ttggctgaga acttccgctc tagaaaagaa
     5101 gtcctttctt ttacgaatct tatttttgaa caactaatgg atccagcagt gggtcaaatc
     5161 aattatgacg aagcagccaa actgatccaa ggattttcag actttccaga gaatgaacag
     5221 tttgagccgg aaatcatgat ctatgaaaaa gaacaggaag aatcagagat tgagattccg
     5281 acggatgata tactggaaga caaaacagaa ggcgaacttt ttatgacagg actaaaaatt
     5341 cgtcaattaa ttgattcctc ctttatgatt tatgataaaa aatcaaaaaa aagtcgtccg
     5401 atagagtaca aagacattgt tctcttgaca cctacaaaga agaacaactt aacgatttta
     5461 gagattttca aaacattgga tattccatta gagatgaatg atgctcaaaa ctattttcaa
     5521 gcgacagaaa ttcgcacgat gatctcgctg ctacaattaa tcgataatcc ctatcaagat
     5581 attccgcttg cggctgtatt gcgctcaccg atcgtgggtc tgattgaacc agaattagcc
     5641 agcattcgat tagctaaccg tgcacatact tactatgatg ctgtgcttgc ttatcaagca
     5701 tcaaacgaag atgaattagc agctaagctg gaacattttg gcaagcaact agagcattgg
     5761 cgagaacttg ctcgccgttc ttcgatcact gacttgttat gggatatcta ttatgagacg
     5821 ggatatctag agtatgtggt cggtctgcca gcaggggcac agagacaagc caatctttat
     5881 gcattggttg atcgtgccaa agcttacgag caaagttctt tcagaggatt ataccagttc
     5941 gtgcgtttca ttgaaaaaat gcaagaaaaa gataaagact tagcagaacc agtcatttca
     6001 atagaagata atgctgttcg cgttatgacg atccatgcaa gtaaaggctt ggaattccca
     6061 gttgtatttt tgttagatat gacaaaggag ttcaacttac aagacttgcg caatcggtat
     6121 gcttttgaag aaaaacttgg agcaggaatt cgctatatgg atcctgaaac acgagtgtta
     6181 tatgatacgt taccgtttca agccatcaaa ttggcaaagc aaaacaaatt gttgtcggaa
     6241 gaaatgcgta aattgtatgt aggattgact cgggcagaac aaaagctttt cattgtcggt
     6301 tcctataaaa ataaagagca aatgatccaa acgtggtctg aagcagctga tcatgaggag
     6361 ttagtttttg atcctgcgct acgtttgaag ggcagaagca gcttgatgaa ttggattggt
     6421 tacggattga tccgtcatcc tgaaatgcag aaatacttag aggaagaaat ttcgacttct
     6481 cttcttcaac attcaaatgc acagttttct atttcatgga tgaatcagca atcgatcatt
     6541 gaacaaagac agttgcttgc tgaaaaagaa ctggttaact tagatcagca gatgaaagaa
     6601 gatgaaactt tattagcaga ttcgttacaa aaacgtctgg catatgaata tccttatcaa
     6661 gcttcttcac aaaccacaag ttatcaatct gtatctgaaa tcaaacgatt attcgaagat
     6721 ccagatgata cacaagaatc acgtttgact ctggaaagca gtcagaacaa agcagcatcc
     6781 cgtcaatttc gttatacgca agaacaacta gcagaaccaa aatttttgca aaaagatcgg
     6841 caagtgtcag cagctgctgt tggaactgct acgcatgctt tgttacaatt actgccatta
     6901 gagatgccaa ctacagagag tatccatcaa aaattacagg aattggtaag gaaacggtta
     6961 gtagacgaaa aagtcgcgaa aaaagtagat gtttcttcta ttatatggtt ctttcaaaca
     7021 gaacttggtc aacagctgat tgccaacaaa gaaaacgtaa aacgagaaca acctttttcc
     7081 atgctgcttc ctgctgacga agtatttcaa gactatccaa atcaagaaga tgaactatta
     7141 atccacggaa tcgtcgatgg atacctagaa gaaaaagatc atctcaatat ctatgatttt
     7201 aaaacagatt ttattttaca tccggatgat ccagcagaaa tagatgcaat cgtccaaaaa
     7261 tatcaaggac agctaagact ttaccaacaa gcaatgtcag aagctttgaa taagccagta
     7321 gaaaatgttt tcctaatttt gcttcgagtg aaacaaatta taaacattaa caaataatta
     7381 taattgagca aacttgactt atgttttgta aggattatgc tatactctgg gaagaggtga
     7441 gtatgatgga gctaacacag acagaattcg ttttatgccc taaatttgaa aaaacattct
     7501 ctattttagg aaaaaaatgg aacggattga ttatcgatgt actactcgaa aacggtccgc
     7561 aacgctttgt tgagcttgcg gcaaaaatcc cgatggtcag tgatcgagta ttagtcgaac
     7621 gcttgaagga attagaaaaa gaaggaatag tcactcgaaa ctttgcctgt agcgaaaaga
     7681 gccgttcaga atatctcttg actgaaaaag gagcagactt gcaaaaagcg atgcgtcaaa
     7741 tacaagtttg gagcgaaaaa tggatcacag aggaagaatg cggttgattt tgtaaaaaaa
     7801 atcttgtaaa ctatagtcca tacgaataag taaagaacga tgacgaaaaa gagtagtttg
     7861 gctaaaccag ttcagggaga tctgtcgcag actgaaagca gatcctgtgt ttgaaaaatg
     7921 aagttcactt tccgagttcg tctgataaaa tcagaccggc aattgtcgtt aacgaagtaa
     7981 gagtgcggtg taagtcattt atccgcaaat taggatggta acgcgaagac ctcgttcctt
     8041 aacaggaatg aggtcttttt gttttgtatt tggaatttaa aggaggaaca agcacatgtc
     8101 tctacaagca caattagaga gcttgaaaga agcaacgctc gtcaaaatca cagcggcaca
     8161 agatttaaat gaattaaatc aaatacgtgt tgaaacgtta ggaaaaaaag gaccgatcac
     8221 agaagtatta cgtgggatga aagatctaag tccagaagag cgaccaaaag tcggaagttt
     8281 cgcaaatgag atccgagatc ttttgacaga agagatcgtg cgaaaaaaac aagtattaga
     8341 agaagaagcg ttaaatgcag ctttggcaaa agaaacaata gacgtgacac tacctggtag
     8401 aaaagtaaaa catggtacac gtcatatcgt gacacaaatc atggaagaaa ttgaagatat
     8461 ttttgtgggt atgggctatc agatcgtaga aggatatgaa gtagaatctg atcattacaa
     8521 tttcgaacgg atgaatctgc caaaagatca tccagcaagg gacatgcaag atactttcta
     8581 tatttcagac gagatattga ttcggacaca tacttcacca gtccaagcac ggacaatgga
     8641 aaaacatgat ttctctaagg gtgctctacg aatgatctcg ccagggaaag tcttccgcag
     8701 agatacagat gatgcgaccc acagtcatca gttccatcaa attgaagggc tagttgttga
     8761 taaaaacatc acaatgggcg accttaaagg aacattagaa gtcgtaatga aaaaaatgtt
     8821 tggggaagat cgtgaaattc gtttgcgtcc aagttatttc ccatttacgg aaccatcagt
     8881 agaagtagat gtcagctgtt tcaaatgtgg tggtgccggt tgtaacgtat gtaaatacac
     8941 tggatggatc gaaattttag gagctggcat ggtacacccg aatgtgttga agatgtcagg
     9001 aatcgatcca gaagaatatt caggctttgc tttcggcctt ggaccagacc gcgtagctat
     9061 gttgcggtat ggagtgaatg atatccgtaa tttctatcaa aatgacttac gtttcttaag
     9121 tcagttcaag ggggagtaag aaaatgttag tttcatataa atggctcaat cgttatgtag
     9181 atttatcgaa tgtaacacca aaagaattag cggataagat gtctgtgaca ggaatcgaag
     9241 tagagggagt aacggttcca gaagaaggct tgaaaaaaat cgttgtcggt gaagtcaagg
     9301 aatgcgtacc acatccagat tctgatcacc tttctatttg tcaagtcgat attggcgaag
     9361 acgaactgtc tcaaatcgtt tgtggagcgc ctaatgtgaa ggttggaatc aaagtgattg
     9421 ttgcacttcc taactcacgt atcgctggta atgtaaaaat caaaaaagga aaaatgcgtg
     9481 gccaagtatc aaatggcatg atttgctcat tacaagaaat tggctattca gatagtgtta
     9541 taccgaaaga atacgctgaa ggtatctatt atatgccaca agaagctgta aatggcgatc
     9601 cagtttttcc ttatttggat atggatgatt cgattattga attatctatc acaccgaatc
     9661 gtgcggatgc attgtcaatg cgtggcgtag cttatgaagt tggggcaatt tatcgtcaga
     9721 ctcctacatt cgatgacgaa aagctggtag aatcctcacg tcctgctagc gataaaattc
     9781 aagtggaagt tgaagataaa gaagcagttc ctgcttatca aatcagaatc attgaaggag
     9841 taagaatcca gccaagtcct caatggctgc aaaatctttt gatgaacgaa ggcattcgtc
     9901 caatcaacaa tgtagtagat gtgacgaact atattttgct tttattcgga caaccactac
     9961 atgcatttga ctacgacaaa ttgaaatcaa aagagatctt tgtccgccgt gcaaaagaaa
    10021 atgaaacatt agtaacacta gatggagaat ctcgggaatt gacaactgac aatctcgtca
    10081 ttactaacgg caaagaacca gttgctttag ctggtgtcat gggagggtta gactcagaga
    10141 tcacgaatga aacaacaaca gttgcactag aatctgcttt atttgatcca atttcgattc
    10201 gtcgtacagc aaaacaattt aatttgcgta gtgaatcctc tgcacgtttt gaaaaaggaa
    10261 tcaaccatgc gactgttgga gaagccagtg aggttgctgc agcaatgatc gtttctcttg
    10321 cgggtgggga agttctacaa ggcgcggtca aaggctcaga gatcaaagca gaagacgtat
    10381 cagtgaagat ttcacttgaa cgcatcaatc aatatttagg aacatctctt gtcgttaaag
    10441 aagtaaatga gatttttgaa gcacttggat ttagctatga agaaaaggag tatgtttatt
    10501 ccgtagtagt accaccaaga cgctgggata tccaaatcga agcagatatt atcgaagaag
    10561 ttgctcgtat ttatggatac gaccagttgc catctacact tccaagtgga gaaacggttg
    10621 ctggaagctt gtcaaaagaa caagaaacta ctcgtaaaat tcgtacaatc tttgaaggaa
    10681 gcggattgag cgaagcaatc agttatgcat tgacaacaga agaaaaatca agacagtttg
    10741 ttataaatga aagtaatatt acacgtttgg actggccaat gagcgaagaa cgttctgtat
    10801 tacgaatgaa tttgatcagc ggactattag atgatatcag ttataacact gcccgaaaaa
    10861 atacagagat tgctttatat gaaattggtc gggtgttctt ccaagaaaat gatccacgta
    10921 cacatctgcc gcaagaagta aaacatgcag caatcgctat ttctggtatt tgggaagaaa
    10981 aagattggca gacgaaagct caaaatgtag actttttcac catcaagggt cttttagaaa
    11041 acttatttga acaactaggc atcactgaag atgtccatta tcaaacagtg acagaaatga
    11101 aggaaatgca tcctggaaga actgctgcga tttaccttgg cgaaaaattt attggttttg
    11161 tcggtcaagt gcatccaacg attacaaaaa gttatgatat tccagaaaca tatgttgctg
    11221 agtttgattt atctgctata gtggaagctg ctcaaaaagg gatcgttttc gaagcagtga
    11281 caaaattccc agcagtcagc cgggacatcg ctttgcttgt aaaagaaact gtgacaaatc
    11341 aggaattaac agaagttatc cgttctgctg ccggaagatt tttaacagat atccaattat
    11401 ttgatgtcta tcaaggagaa aacattgaaa aaggacataa atccatggcg tatagcctga
    11461 cattcgtcaa cccagaagca acattgacag atgaagaaat caataaagca atggaaaaag
    11521 tcgaaaaagc gttggtagaa aacctagagg caagtattcg ctaagaagga aaatatagta
    11581 agtaacgatc aagtagcttt tgaagaccat acatttgaaa aaaagatgtg acacaacttc
    11641 gtcacatctc tttttttgat tttaaaaaag gaatagcaca gagacgagat aaaaaaacag
    11701 gcctttacag cctgcttttt tagagtaaat gaattaatgg aagtaattga ttcccattgc
    11761 tgattttact tcagaaagtg tttgtgcagc tactttagca gcttcttcac tacctttacg
    11821 taagatttcc ataacagctg aaggatcttt ttccaattct tctcggcgcg cacggatcgg
    11881 tgcaaattca gcttccaata catcaatgag gtatcgtttg atctttacat caccaagtcc
    11941 gccgcggcgg taatgagctt tcatttcttc aattgcttct ttatctgttc cgaatacatc
    12001 caagtaggtg aagaccatat tcccttctac ttgtccagga tcttgtacat ggatgtggtt
    12061 tggatcagta tacatactca tgactttttt ctgtaagaca tcggcaggat cggagatata
    12121 aataccgttt cctaacgatt tactcatttt gccatttcca tcgattccag gtaatctacc
    12181 cattcctttt ggtgggaata cgccttttgg ttccaccaag acttcaccat atgtatgatt
    12241 gaagctttgt acgatttcct gtgtctgctc tagcattggt ttttgatcct caccaacagg
    12301 tacaagattc gctttgaatg cagtgatatc tgctgcttga gaaacaggat agataaagaa
    12361 tcctgtaggc acgctttcac cgaatttttt ttgttcgatt tctgttttga cagtcggatt
    12421 gcgccgaacg cgtcctacgc tgactaagtt caaataatac atggttaatt cagctaattc
    12481 cggaatttgt gattggataa ataaagtaga ttttgcagga tctaatccca cggctaaata
    12541 gtctaaagca acttgcaaga catttgatga aaccttctca ggatttttag cattatctgt
    12601 cagtgcttgc atgtcagcaa tcatgacaaa cagttggttg tcttcatctg cctgcatagc
    12661 cactcgggtt tttagagaac cgacgtaatg ccctaaatgc agcttcccag ttggtcgatc
    12721 tcccgttaaa ataatatttt tcaaaaaaga cacctcttta cgatttgtaa gtctgagcac
    12781 ttaatatctt accgtttttc ctgaaaagaa acaacagttc cta
//
LOCUS       DAXLPC010000075        12753 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.075, whole genome shotgun sequence.
ACCESSION   DAXLPC010000075 DAXLPC010000000
VERSION     DAXLPC010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12753
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.075"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            107..844
                     /locus_tag="ACF3UE_002078"
     CDS             107..844
                     /locus_tag="ACF3UE_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD3635458.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            858..1673
                     /locus_tag="ACF3UE_002079"
     CDS             858..1673
                     /locus_tag="ACF3UE_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFD3635459.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            1686..2333
                     /locus_tag="ACF3UE_002080"
     CDS             1686..2333
                     /locus_tag="ACF3UE_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD3635460.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            2349..3005
                     /locus_tag="ACF3UE_002081"
     CDS             2349..3005
                     /locus_tag="ACF3UE_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD3635461.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            3167..3988
                     /gene="racE"
                     /locus_tag="ACF3UE_002082"
     CDS             3167..3988
                     /gene="racE"
                     /locus_tag="ACF3UE_002082"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFD3635462.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            3991..5346
                     /gene="rph"
                     /locus_tag="ACF3UE_002083"
     CDS             3991..5346
                     /gene="rph"
                     /locus_tag="ACF3UE_002083"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFD3635463.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            5347..5865
                     /locus_tag="ACF3UE_002084"
     CDS             5347..5865
                     /locus_tag="ACF3UE_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFD3635464.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            5972..6472
                     /gene="cbpB"
                     /locus_tag="ACF3UE_002085"
     CDS             5972..6472
                     /gene="cbpB"
                     /locus_tag="ACF3UE_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFD3635465.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(6752..7672)
                     /locus_tag="ACF3UE_002086"
     CDS             complement(6752..7672)
                     /locus_tag="ACF3UE_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFD3635466.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            7798..8850
                     /locus_tag="ACF3UE_002087"
     CDS             7798..8850
                     /locus_tag="ACF3UE_002087"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFD3635467.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(8960..9715)
                     /gene="fabI"
                     /locus_tag="ACF3UE_002088"
     CDS             complement(8960..9715)
                     /gene="fabI"
                     /locus_tag="ACF3UE_002088"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFD3635468.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            9935..10375
                     /gene="fabZ"
                     /locus_tag="ACF3UE_002089"
     CDS             9935..10375
                     /gene="fabZ"
                     /locus_tag="ACF3UE_002089"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFD3635469.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(10490..11251)
                     /locus_tag="ACF3UE_002090"
     CDS             complement(10490..11251)
                     /locus_tag="ACF3UE_002090"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3635470.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            11440..12534
                     /locus_tag="ACF3UE_002091"
     CDS             11440..12534
                     /locus_tag="ACF3UE_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFD3635471.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(12620..>12753)
                     /locus_tag="ACF3UE_002092"
     CDS             complement(12620..>12753)
                     /locus_tag="ACF3UE_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3635472.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         4116 a         2202 c         2671 g         3764 t
ORIGIN      
        1 taaacgttct aagaaacttt acaaattact aaactatcag atataatgta ttttattata
       61 catctttaaa agaaatctta ctaaataata atgggagtgt aattctatgg caatgattaa
      121 atttgatcac gtggataaat attatggcaa gttccacgca ttaaaaaata tcaatctcga
      181 attcgagaaa ggagaagttg tcgttgtcat tggtccttct ggttcaggaa agagcacgat
      241 gcttcgctgt atcaatggat tagagacgat ctcttcaggt aagctgctga ttaatgatac
      301 tgacttgcat gataaaaaga caaaactgac agaagtccga aaaaacatcg gcatggtttt
      361 ccaacatttc aatttgtacc caaataaaac tgttctggaa aacatcaaat tagcaccaat
      421 caaagtgttg aagcaagacc aggcaactgc agtcaaaaac gcggagaaat ttttgaaaac
      481 tgtcaatatg ttagataaga aagattctta tccttccatg ttatccgggg gacaacagca
      541 acgggtggca atcgccagag gtttagcgat gaatcctgag atgctgctgt ttgatgaacc
      601 tacttctgct ttggatccgg aaatgattgg tgatgtatta gacgttatga aaaaattggc
      661 tcatgacggt atgtcaatga ttgtcgtgac acatgaaatg ggctttgcca aagaagtggc
      721 ggatcgtgtt atcttcatgg ctgatggaga agtattggaa gacagcagaa atgtgagaga
      781 ctttttcgaa aatccaaatg aagtccgagc acagcaattt atcagtaaag ttatcaatca
      841 ttgataggag gaaaaagatg cgcaggttaa aaaaaatacg cctgattttc cttttaggca
      901 ttgcttttct tgcactagcc ggatgtaaag gaaatgggtt ggcaaatgaa gatattttag
      961 agcgaagcaa atctaccaat gaaatcatct ggggtgtcaa gtatgatact cgattatttg
     1021 gaatgatgga tattgagagc agaactgtac aaggatttga tgtagatatt gcaaaagcaa
     1081 tcactaaaaa gatccttggt gacaatggaa aaacagaatt tgttgaagtc acttctaaaa
     1141 ctcggattcc attattgaaa aacggaaata tcgatgcaat tattgcaacg atgacgatca
     1201 cagatgaacg aaaaaaacag gttgactttt cagatgtcta tttcgatgct ggccaagctt
     1261 tgttggtaaa gaaaggaagc caaatcaaaa gtgtagatga tttgaatgct tctacaacgg
     1321 ttctagcagt caaaggttct acatcggctg cgaatatccg acagcatgca ccagatgcaa
     1381 aaattttaga attagaaaac tatgcagaag catttactgc tttacaatct ggtcagggag
     1441 acgcgatgac tacggataat gcgattttgt tagggattgc agatgaaaat ccagagtatg
     1501 agttagttgg tggaacgttt actaatgagc cttacgggat tgcgatcaac aaagggcaag
     1561 aaaacttctt gaaagctgtt aaccaagcgc tagaggaaat gcatgcagat ggcacatacg
     1621 ataaaatcta tcaaaaatgg tttccaaatg aaactgaagg aaaagtagag taagggggag
     1681 aggcaatgag cgaattgata caaacttatg gaccaatctt tgtcgacggg ttcaagatca
     1741 cattgttttc gagtgtctta gcacttgtgt ttagtttgat tatcggaacg ttaatggcaa
     1801 tcttccaatt atcaaagaat aaagtagtga gcgccttagc aaaggcatat gtagaatttt
     1861 ttagaaacat tccattatta atcatcgtga tgttttttta tgttgtcgta ccgatttatt
     1921 ggtttaatct agatggattc caagcaggta cgattggatt aacgatctat acatctgctt
     1981 ttattgctga aacagtacgt tcagggattc aaaccgtacc aaaaggtcaa acagaagcag
     2041 gactatcttc tggttttacc tattcagaaa tcatgcgtta tattgtttta ccgcaagcat
     2101 tcaaaatcgt tatcccgcca ttaggcaacc aatttatcaa cctcgtaaaa aactcatcta
     2161 ttttagcaat cgtagctggt ttagatttga tgtatcaagg agacttgatc gctagtgaaa
     2221 cattcaatac cttcgatacg tatatcatcg ttgggttatt ttacttagtt atcacgctac
     2281 cgttatctta cttaatggtt tatcttgaga aaaaatgggc ggttcgttca tagaaggagg
     2341 ggaaatacat ggattttagc ggcgcttttt catggatgaa tatccgtttt ttattggaag
     2401 gattaaaggt tactgttgaa gtttcattgt tttcgatcat ttttagtttc ttgatcggtg
     2461 gtctgacagg tgtgattcgt tttgcgaata tccctttctt ttccaaaatc cttggtgtag
     2521 tgattgatat tatacggaat cttccattat tattgatcat tttcttcact tactttgcct
     2581 tacctcaaat cggcattcag atgaacatct tctggtccgc tgtcgcagca ttaacgattt
     2641 ttgagtcagc tatgttgtcg gaaattttcc gagctggact caatgctgtt ccaaaaggac
     2701 agatggaagc aggattatca acgggactga cttatgtaga atcgatgcga acgatcgtgt
     2761 taccgcaagc atttaaatca atgatcccgg caattgtgag ccaattgatt tcactgatca
     2821 aagatacttc attagcagta atcatttctt tacctgaact ttctcatcag gcacgtatta
     2881 tttatggaca gaacaccaat tatgtgcttc cgatgttcat catcatgaca cttatgtact
     2941 tcgtggtatg ttacgcgctt tctctgcttt ccggttactt ggaaaagaga cggtacagtt
     3001 attaatagat gattctttta gcggttgtgg caaactaaag tcacaaccgc ttttcctctt
     3061 tccattcgaa aaaaagagat ttcgattgtt ttaagcaagt aagagcactt gaaaattcac
     3121 gctaaaaagt acacaatagg gaggatagaa tttattgaaa aaaaggatga tacgattgac
     3181 agataatcgc cctatcggat ttattgattc aggtgtcggc ggcttgactg tagtaaaaga
     3241 agccctgaaa caattaccga atgaaaatat tttatttgta ggagacacag cacgctgccc
     3301 atatggccct agacccgcgg aacaggtaat ccagtatact tgggaaatga cggattatct
     3361 ggtggagcaa ggaatcaaga tgctggtgat cgcctgcaat accgcaactg cggtggcttt
     3421 agaagaaatc aaagctgctc tttctattcc agtcatcggt gtgatccttc ccggtactag
     3481 agcggcagta aaaaaaacac aaaataaaca agttggcatt atcggtacga ttggtacggt
     3541 aaaaagtcaa gcttatgaaa aagcactgaa agagaaagta ccagaattga ctgtgacaag
     3601 tcttgcttgt cccaaatttg tttcagttgt cgaaagtaat gaataccatt catcggtggc
     3661 gaaaaaaatt gtggcagaaa cattagctcc tttaaccact aaaaaaatcg atacattgat
     3721 tttgggatgc acccattatc cattattacg ccccatcatt caaaatgtaa tgggagaaaa
     3781 tgttcaactg atcgattctg gagcagaaac agtaggtgaa gtatctatgc tgttagatta
     3841 tttcaatttg agcaattcac cgcaaaatgg tcggacatta tgccagtttt atacaactgg
     3901 ctctgccaaa cttttcgagg aaatagctga agactggctt ggaatcggac acttaaatgt
     3961 agaacatatc gaattgggag gaaaataagg atgcgtcatg acgggagaaa agcccaagag
     4021 cttcgcaaac tggagcttca aacaaatgtt ttcaaatatc cagaaggatc ggtagtgatc
     4081 cgttttggtg atacaacagt tatttgttct gcaacaatag aaaattctgt tccccctttt
     4141 ttgagagaaa caggaacagg atgggtgaca gcagaatata gtatgctgcc tcgagcaacg
     4201 agtacgagaa atcgtagaga aagcagcaaa gggaaacttt ctggtagaac aatggaaatc
     4261 cagcgtctta ttggtcgttc cttgcgtgca gtagtagact tggaaaaatt aggagaacgt
     4321 agtatcatcg tagactgcga tgtgatccaa gcggatggcg gtactagaac agcaagtatc
     4381 actggggcat ttgtggcatt gaaattagcc attgaaaaac ttttaagaga aaaagaattg
     4441 tcagaagatc caataaaaga acatcttgct gcagttagcg taggaatctt accagatggg
     4501 acttgcgtca cagatttgga ttaccaagaa gattccgcag cacttgtaga catgaatctt
     4561 gtaatgacag aatctggaaa attcgtggag attcaaggaa ctggagaaga agcaacgttt
     4621 gatggtgaac agttgaatga aatgctcttt tttggaaaaa acgcgattga agatttgatc
     4681 aaagagcaaa aacatgcttt gctaacagag tttgctcaaa atgatgagcg gatagaagaa
     4741 acaaaaacaa tcatcattgc gacaagaaat ccaggaaaag cagaagagtt tcgaaatatg
     4801 ttcaaagaag cgggatatca tgtaaaaaca ttacttgact atcctgaatt gccagatgtg
     4861 gaagaaactg gcagcacatt tgaagaaaat gcccgattaa aagcagaaac gattgcacaa
     4921 ttgcttgatc agccagtctt agcagatgat tcaggtttga aagtggatgc tttaggcggt
     4981 atgccaggaa tctattctgc acgttttgca ggggaacaaa aaagtgatgc ggggaataac
     5041 gccaaattat tatatgaatt gacagatgtg ccggatgaaa aaagaacagc acaattccat
     5101 tgtacgttag tattcgcggc acccaaaaaa gacagccttg tagtagaagc ggaatggccc
     5161 ggtcgagtag cccgtatacc atctggcgaa aatggctttg ggtatgatcc tttatttatc
     5221 ccagaaggta agaaacaaac agcagcagaa ttatcgagcg aagaaaaaaa caagatcagt
     5281 catcgggctc aagcaatgaa aaaattgagt gccgagtgga aacaatggct ggaaggagag
     5341 agatagatgc ggtatttagt agtaagtgat aatcatggag acagagatat cctcgttgac
     5401 ttagtagatc gttatcgttc tgaagtggat atctttttcc attgtggtga ttcggaatta
     5461 gaagcttctg acccattatg ggatacattc caagtggttc aaggtaattg tgattatgga
     5521 ccaggattcg aacagaaaaa agtgatccaa actggtcagg atacagtatt catgactcac
     5581 ggtcatttat cgaatgtccg atttggtttg acacagttag caatcgaagc tcgagctgca
     5641 actgccgata tggtgttttt tggtcatacc catcaaatag gctgtgagat ggatcagaaa
     5701 atcctgtttt tgaatcctgg tagcatttct cagcctagag gcccgatcca aatcccatca
     5761 tatgctctta tcgaaagttt agatgaccaa atttctgttc aatactataa ccgtgcccat
     5821 caggcagttg aagagttggc cttttctttt tcgagagagc gctgaataaa aaaactctaa
     5881 tttttaataa aaataagctt tattttatga attttgcatc cggtttcggt aaaatagtag
     5941 tgttgaatga aatagaaatg gaggccatca gatgattgga cctatagtaa gagaaatgct
     6001 gctggaaaat caggaaacgt ttttgattcc tgcagaaaat gtggcaaatg ttatgtatca
     6061 tcatccattg tcccatggtt tacttgtgtt atcgaaggtc ggttattcca aaattcctgt
     6121 attaggaaaa gatgatcact ttgtaggact agtaagttta tcagatgtgg tcaataaaat
     6181 gattgacttg caaacaatca gcatggaccc gttagaagga ctaacggttg ctgatgtgac
     6241 agaaacagat gttccgacaa ttgatgaaaa ttgggaacta gaagaagtac tccatttgtt
     6301 agtcgattcg ccttttttac cggttgtcac agaagatcgg attttcaaag gaatcattac
     6361 aagaaaagag ctgcttaaag ccgtaaactt catggtgcat gaattagaac gtcgtaatat
     6421 attgtctccg aaaatcgaag aattaaaaga acaaatcgat atcgtgagct aaagaacgag
     6481 aaactaaaag ataatcaaaa aataagtaga aaaaacagcg taccagtttt gactttatct
     6541 tgaaaaagag gctgggacaa aagcgtttaa ctccaagaaa taagaaggaa ttcacgaaaa
     6601 ttgcttttca aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc
     6661 cgtttatacg tgtttagagc gtgggacaaa agtgttcttt acttttgtcc cacgctcttt
     6721 ttagtgagat tcgttgcatc gtttgtccaa attattttcc gacagcaatt ggactgttcg
     6781 gaatcgtgaa accagaagct gtcaattctt tgacatagga gctcaagaac tcttctttta
     6841 aggcatattg ttttccgttc aatgcgtagc agaccgtacg aatcgcaaaa ttgctgtttc
     6901 caagatccac taatccaaag atagaaggtt cagtttggag ctcttcttgg tatttttcag
     6961 ctaatgtacg atttactcga tcaatgatct catagatttt gtcatatcct tcttcaggaa
     7021 caatccgaat atctaaaagt acttgcatat ttgcacgaga gagattgctg atcgtggtga
     7081 tgtttcgatt cgggatgaaa tggacagtac catccgttgc tttcagctga agggtacgga
     7141 taccaacaga tacgacggtt ccttcaatcg ttaagtttgc tagcttgatg tagtccccaa
     7201 catccatctg ttgttccatg ataataaaaa atccggtaat aacatcactc atgaaccctt
     7261 gggcaccaag accgattgcc acacctgcaa ttccggcacc agccaaaagt gatccgatcg
     7321 gcacaccgat agcagataaa attgcataga taaaaaagaa accaagggta taatgaaaaa
     7381 tagtatttaa aagactatgt aaagtcttta agcggctctc gtttagaatg gcttttttag
     7441 aatactgatt aaaagactta tcaatcagat attttcccac acggtgaaga atccaaaaaa
     7501 ggacgatcaa aaaaatcaga tataaacttt tttggataaa ggcagccaaa atggcgtccc
     7561 aatcaatccc gtcccaaaac cgctgaaacg catttacttt gctgacagct tgatctgtca
     7621 atgtctcgcc agaagagtct gtcgtaccgg cagttgctaa taatgaaaac ataaaatcct
     7681 cttttctaaa atttgattct ttctgtattg taccaagaag ttttcaaaaa aggaaatagc
     7741 aaaaataact ataatgaagg aaaaaagctg aaaataaaat gacaaataat atggataatg
     7801 ataaaatgtg gagaaaataa cgaaggtggt aagtatatgc aaatcgattg gaacaatcta
     7861 ggtttttctt atatcaaaac tccttggcgt tttattgcca aatggaaaga cggacaatgg
     7921 gaagaaggag aattgacaga agataattac ctgacgattc atgaaggctc tccagcgctt
     7981 cattatggtc agcaatgttt tgaaggtcta aaagcttatc gtcgaaaaga cggcaaggtc
     8041 aatctctttc gacctgaaca aaatagtcga cggatgaatc aaagtgctag acgattgctg
     8101 atgccaatgg tccctgaaaa gatgttcgtt gatgctgtca agcaagtggt aaaagcaaat
     8161 gaagattttg tgccgcccta tggaacaggc gctacattat acttgcgccc tttactgatt
     8221 ggggtcggtg aaaacattgg tgtccatcca gctccagaat atttatttgt cgtcttctgt
     8281 acgccagtag gagcgtattt caaaggtgga ctaaaaccaa cgaattttat tgtatctgat
     8341 tacgatcgtg ctgctcctaa ggggactggt gcagcaaaag tcggcggaaa ttacgcagcg
     8401 agtttacttc caggaacaga agcaaaagaa ctggattact cagattgtgt ttatcttgat
     8461 ccagccacac atacgaaaat cgaagaagta ggtgcagcaa atttctttgg aattacaaaa
     8521 gacggaaaat tcatcactcc gcaatcgccc tctatcttac caagtatcac gaaatattcc
     8581 ttgttgcagt tagctgaaga acgactagga ctgcaagcaa ttgaaggaga tattttcatt
     8641 gatgatctag atcaatttgc agaagctggt gcatgtggta cagcggctgt tatttctcca
     8701 atcggtggga tttatcacaa taacaatctt catgtatttt atagtgaaac ggaagtagga
     8761 ccagtaacaa aacggttgta tgatgaattg acaggtattc aatttggaga catagaagca
     8821 ccagaaggct ggattgaagt cgtggaataa tttcaaagta atgagttgaa aaaaacgtaa
     8881 aaagaaaaaa tcaggaagag actttaaaaa gttttttcct gatttttata tgttttactt
     8941 taaagaatgc aacaaaagtt tatgaaagat ggacaccttt gtcaacgtag ataatatcac
     9001 cgatgattcc gctggaaagt gggctgatta agaaagcaca agcattaccg acttcttcga
     9061 tcgtcacacc ttgctgatca ggcgtacgag attcagataa ctggatcagt ttttgatagt
     9121 ctttaacacc tgtgacagct aatgttttga ttgccccagc tgagattcca ttgacccgaa
     9181 ttcctttagg cgagaactca gctgccaaat aacggatagc agcttcaaga gaagctttcg
     9241 caatacccat catgttataa ttcgggattg cgcgttctga acctagataa gtcatgctaa
     9301 cgatcccgct gtttggtgca agaaacggtt gtgcgtattt tgatacagca attaaagagt
     9361 agctgctgat atcttgagct aattgatagc cgtctctgga aatatcagac acatttccgg
     9421 acaattcttc tttgttggcg taagcaactg catggacaag gccgtggatc tccccagcat
     9481 attcaccgat ggcattcatt gctttttcga tgctttcgtc gctagaaaca tcacattcta
     9541 cagtgaatgc ttcttcgccg accaatttga ctaatgattt tttcattcgt tcattttggt
     9601 aagtatagat aatttctgcc ccttgtttca acattgcttc agcacaaccc caagcaatgc
     9661 tttttttgtt agcgacgccc ataatgacga ttttttttcc ttctagaaat gacataatga
     9721 ctctcctttg tttctgataa aaatttgata gtcgtaaaaa aatagagaat aatagctaaa
     9781 ataacttctt gatttcttaa ttattagtca aaatgttttg attgtcaaac tattttttct
     9841 taaattaaaa aaagattgct aaatatttag gaatatgata ctttgatagt caaagtaatg
     9901 aaaatggcaa ttgcctgaaa gaaggagttt aattatgtct tacgtattat ctgctactga
     9961 agtaatggaa ttgattccta atcgttatcc tatttgttat attgattatg tagatacttt
    10021 agaaccagga aaaaagatcg ttgcgacaaa aaatgtaaca atcaatgaag attttttcca
    10081 aggtcacttt cctgacaatc cagtgatgcc gggtgcgttg attctagaaa cactggcaca
    10141 agcaggttcg atacttatcc taaaatcaga agagtttcta ggaaaaagag cttatatcgg
    10201 tgggatcaat aaggccaaat tccgtcaaaa agttgttcca ggagatgtgc tgaaatgtca
    10261 ttttgaaatc accaaaatga agggatcagt cggtacagcg ttatctgcag catatgtaga
    10321 tgataaaaaa gtctgtgagt gcgagttcac gttcatcgtc aaccaaaatg cttgactata
    10381 aaacctgata tagcaaaaca aaaggaagct tacttgcttt ttatgtaaaa agaagacgcc
    10441 tgaatcctag catacgttgt catctatgca ggattcagac gttatttttt tatttttgtt
    10501 ttgcttcttg cagtatattg attttatcga tttttacttc ttcttttggt ttgtctgaac
    10561 tatctgtttc gatatttgca atagcatcca cgacatccat tccttcaatc acttggccga
    10621 agacagtata atggccatct agtgaaggat aaccgccgtt tttataagcg tcgatgattg
    10681 cttgaggata gtcgtctttt aaaagaccat catgcatatc atctgtattt tgaacgataa
    10741 agaactggct gccgttactg ttaggatctt gtgagcgagc catagataac gcacctctta
    10801 tattataaag gtggttgttg atctctgttt caaatccttc tccccaaatg ctttcccctc
    10861 cagtgccatc gcctttagga tcgccacctt ggatcatgaa atctttgatg acgcgatgga
    10921 aagtcagtcc gttgtagtaa ccgtcttttg catgtgtcat aaagttttca accgcttttg
    10981 gtgcgtgttc gggaaataat ttgattttga ttgtgccttt attcgtcacc atttcgacca
    11041 gatcttcatt ttcggcgaca tctttcgtca attgtggtaa ttccaatgcg ttcaaatcga
    11101 cgctactggc agtcgtgctt tccgcagtag atgtactttt tgaactttct gtagacgaac
    11161 tagaagaagt cgtgttgttt gcagaacaac cagcagcaaa cagcaatgct gctgctaaac
    11221 taatacttaa aataacttta tttttcttca taactgttcc tttccaattt actattttgt
    11281 tatctttaat gataacaaaa tagagggaaa atacctactt aaattattgg aatttatcat
    11341 ttattttaaa agaaaaagaa aaggtgtaga ccatttactt tgtgtttgct ataatgtaag
    11401 tggatacaaa aacgaaaaga tgcaggagga aatggtaata tgggaaaatt aggaatctcg
    11461 atttatccag aacggtcaac atttgaaaag gacaaagcgt acttggattt agctcataag
    11521 tatgggtata aacgggtttt taccagtttg ctgcagatca atgatgataa agaaaaagtt
    11581 ctttcagaat ttaaagaagt agttgattac gcgaatagcc taggcatgga agtaatggtt
    11641 gatatcaatc cagcgttatt tgaacagttg gagatttctt acgatgactt atcttttttc
    11701 cataagatgg gtgcctacgg ggtccgctta gatatcggat tcacaggagc agaagaagca
    11761 aaaatgacgc gcaatccttt tggtatcaaa atcgagatca atatgagttc gggcacgaat
    11821 tacgttgaca acatcatgag ttattcgcca aacacggata atttattagg ttctcataat
    11881 ttttatcctc atcgatactc tggtttagga tacgaacact ttgttttttg ttcagaaaaa
    11941 ttcagaaaat ataatttgaa tacgatggca ttcgtcaatt cgcaatctgc tgagtttggc
    12001 ccttggccta cgcaagatgg cttgtgcacg ctggaagacc accgagatct tgaaattgcg
    12061 acacaagtga agcatttaat ccttacagga ttgattgatg atatttctat tggaaatgcg
    12121 tacgcaagtg aagaagaatt gaaagaaatg gcagaagcat ttaacgcgga ttatccaaca
    12181 ttgaaagtag atacggaaga aggtattaca gaaaacgaac gaatctgctt gtttgataac
    12241 cttcatagtt atcgagggga tcgctcagaa tatatccttc gttcaacgat gactcgtgta
    12301 tactacaaag ataaagattt cccgcctcat aatacgcgag atatgcatca tggggatgta
    12361 ctgattgaca atgaagggta cggtcaatac aaaggagaaa cacaaatcgc cttgaaggat
    12421 atgaaaaacg acggacgtgt caatgttgta ggaagaatct ccgatgacga attattcctc
    12481 cttgactttt tgaaaccatg gtcaagcttt aaattaattg aaaataaaaa atagataatt
    12541 agttattgca gaaataatcc gctagaaata gccagttatt tctgcttttt tattttgttt
    12601 ttttataggt tatgatttgt caaattaagc tagaataaaa tgcttcttgt acatagctca
    12661 aaaatatttc gattggtgtt ctgtaattca atgattttct tggaatatga ttacgttgat
    12721 tgctgacact ggaaataaat gtctgattca ctt
//
LOCUS       DAXLPC010000076        12456 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.076, whole genome shotgun sequence.
ACCESSION   DAXLPC010000076 DAXLPC010000000
VERSION     DAXLPC010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.076"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..153
                     /locus_tag="ACF3UE_002093"
     CDS             <1..153
                     /locus_tag="ACF3UE_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFD3635473.1"
                     /translation="SLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTL
                     RYSLGY"
     gene            complement(207..485)
                     /locus_tag="ACF3UE_002094"
     CDS             complement(207..485)
                     /locus_tag="ACF3UE_002094"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635474.1"
                     /translation="MENKVGYVRYNFFSSTPIMKDFASFNEALAVELSHDRERIHYEK
                     HVIINDLWNTEKTDLLALPDTDYPVFKEIEVKANKYNEIKQNKITNLS"
     gene            complement(600..1208)
                     /locus_tag="ACF3UE_002095"
     CDS             complement(600..1208)
                     /locus_tag="ACF3UE_002095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635475.1"
                     /translation="MTDINTIRNLRNNHDKSINHIAKELDVNWRTAKKYADDDLLPQP
                     KARKKTGMMYTEKWGGIVSLWLSEDAKLPNKKRRTAEAMTTALKADGFPGSYRTVCVF
                     IQDWKATHYLETLEDQGFERLEHPPAEAQLDFGTMEVCHDGAFKDVKVLVMTFPFSNA
                     GFAVVLPAENQECLLEGMKELFSQSGGVPRKIRIDNMSTAVT"
     gene            complement(1612..2436)
                     /locus_tag="ACF3UE_002096"
     CDS             complement(1612..2436)
                     /locus_tag="ACF3UE_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD3635476.1"
                     /translation="MEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAGANKKLV
                     YNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLKILTTFL
                     YVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKFVYDDFS
                     DELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGIPYINNL
                     GLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQHLEIS"
     gene            2779..3195
                     /locus_tag="ACF3UE_002097"
     CDS             2779..3195
                     /locus_tag="ACF3UE_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3635477.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3192..3662
                     /locus_tag="ACF3UE_002098"
     CDS             3192..3662
                     /locus_tag="ACF3UE_002098"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3635478.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3676..4449
                     /locus_tag="ACF3UE_002099"
     CDS             3676..4449
                     /locus_tag="ACF3UE_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3635479.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4463..5275
                     /locus_tag="ACF3UE_002100"
     CDS             4463..5275
                     /locus_tag="ACF3UE_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3635480.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5329..6294
                     /locus_tag="ACF3UE_002101"
     CDS             5329..6294
                     /locus_tag="ACF3UE_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3635481.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6431..9154
                     /locus_tag="ACF3UE_002102"
     CDS             6431..9154
                     /locus_tag="ACF3UE_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3635482.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            9167..9799
                     /locus_tag="ACF3UE_002103"
     CDS             9167..9799
                     /locus_tag="ACF3UE_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3635483.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            10007..10231
                     /locus_tag="ACF3UE_002104"
     CDS             10007..10231
                     /locus_tag="ACF3UE_002104"
                     /inference="COORDINATES: protein motif:HMM:NF015692.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HFD3635484.1"
                     /translation="MQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEVI
                     PENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10333..10566
                     /gene="relB"
                     /locus_tag="ACF3UE_002105"
     CDS             10333..10566
                     /gene="relB"
                     /locus_tag="ACF3UE_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFD3635485.1"
                     /translation="MSQSTITFRIPDDEKELVLEYAKAHNSSLTELYRNAVLDKIEDE
                     IDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10556..10825
                     /locus_tag="ACF3UE_002106"
     CDS             10556..10825
                     /locus_tag="ACF3UE_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFD3635486.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
     gene            complement(11004..12305)
                     /locus_tag="ACF3UE_002107"
     CDS             complement(11004..12305)
                     /locus_tag="ACF3UE_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFD3635487.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         4065 a         2016 c         2444 g         3931 t
ORIGIN      
        1 tccttagaaa aattaggttg tcaaaatttc aactcacgtt ctgttaaagg gctagagagt
       61 agatttgaaa gcatattact ggcttacagt gttctattaa gtcgagcaca acgacgtttt
      121 gaaggaactt tgagatattc tttaggatat taaaattaac tagcaccacg ggtaaaataa
      181 atagtttttc tatcaagtat attgaactac gataaatttg ttattttgtt ttgtttaatt
      241 tcgttgtact tattggcttt gacttcgatt tctttaaata ctgggtaatc ggtgtccggc
      301 aaagctagca aatctgtttt ttctgtgttc catagatcat tgataatgac atgtttttcg
      361 taatggattc gctctcgatc gtgtgacagc tccaccgcta atgcctcgtt gaaactggcg
      421 aaatccttca taatcggtgt agatgaaaag aagttgtacc gtacatagcc gactttgttt
      481 tccatactac ctttctcgtt tccgctacgt ggattgcaca cctgtgtctc aaaaccatag
      541 tgcatagaaa atcggaggaa accgtcagtc agcaccgctt gttcagtctt tgtttttgtc
      601 taagtaacgg ccgttgacat attatcaatc cgtattttcc gaggaacgcc acctgattgg
      661 ctgaagagtt ctttcatgcc ttccaacaaa cattcttgat tctcggcggg gagtacaacg
      721 gcgaatcctg cattactaaa agggaaagtc atcactaata ccttcacatc tttaaacgct
      781 ccatcgtgac aaacttccat cgtaccaaaa tcaagttgcg cttctgctgg cgggtgttca
      841 agacgctcaa agccttggtc ttccagtgtt tccaagtagt gtgtcgcttt ccaatcttga
      901 atgaatacac agactgttcg gtaggatcct ggaaagccat cggcttttaa agcagtagtc
      961 attgcttcag cagtcctacg ctttttattt ggcagcttag catcttctga aagccatagg
     1021 gaaacgatgc ctccccactt ttctgtatac atcataccag tctttttgcg tgctttaggt
     1081 tgcggcagca aatcatcatc tgcatatttt ttagccgtgc gccaatttac atctagctcc
     1141 tttgcaatat gattaatgga tttatcatga ttatttcgta aatttctgat agtattaata
     1201 tcggtcattg tgagcatacc tttcttacct ccagttacag tgtcgagact ataactttag
     1261 aggagtttca ggttgcccgc aatggctttt tatcttaact taatcgattt gcggagttgt
     1321 gtagtttttc gttgcacttg tatgtacttt tattctgcca taaacagctt aatgaatgtc
     1381 cacttgaaaa agtgaataaa cgaaatagat gactcgattt aataaggaag taaacccaca
     1441 cagaaatata ggtgattttc cttgaatgac caagatattg aaagttagtg aaaaaacaca
     1501 aaaaggtagc cctattcaca gaaggtctgc cttttgtgtt atcgccagca aacattagag
     1561 ggggtatttc atatagcttt tgtcctctcg acagtcctat cagtttctct tttaacttat
     1621 ctctaagtgc tgtccagttt taatagcttc tagcttgttt cctaactgtg tttttaatat
     1681 gttgaaggct tttgaacctg tgcagtggca agtaaggatt ttttctactc gtgagtcatt
     1741 caatttattt ccaattttca ttacctcttg ctcaggtaga cctaaattat ttatataagg
     1801 tatgccaatc atatggaagc caccaattag gtattttatg ggtttagtcg gaaatgtttc
     1861 aagagcaatt tccatcatat cgataatgcc atgatgacta cagccagtaa agacaatcag
     1921 accgtcttct tgctcaatta cgaccaataa ttcatctgaa aaatcatcat aaacaaattt
     1981 atcatccatc tttttgtata aattcttggt ggtcgagttt gctttgccta gggggatgat
     2041 atggaagctc ggagcaagtt ctgttttcgt ttttattgta tgtaaattct catgcatttt
     2101 aaggatttca tttttaggaa taccaacata cagaaacgtg gttaaaatct ttaaataatg
     2161 gggtaaagtt acaccttcag ctgtataaat aggggcgttt cctgatttta aatatcttaa
     2221 cccgccggtg tggtcagaat gaccgtgtga aataatcact gcctccagat cattcaaagt
     2281 ttcccccatt ttagtcgcat tatagactaa ttttttatta gcgccagcat cgaagagata
     2341 tttcttccct gagtagttaa ttaagagaga taacccatgt ccacttttaa agttcaaatt
     2401 tattcttgag ttttcaaata aaaccttgat ttccactata acatctcctt tcacatgaac
     2461 gcgtattcat atattgtagc acattaagtt ctattttttg ttgtaattac cgaaaaaaat
     2521 attaatggac gctttttacg ctttatttcg tatgtggaag aaaatttctt aggatgtggc
     2581 gggggattgg ggcaaagcta aattccaatt acagtgatca tttaattaga cacctttaaa
     2641 tacccacact ttcatcaaca ctataattta gggaaagaaa agtgttggca tgatatagaa
     2701 aaacctttaa ttaacagcgt ttcctaaaat tggcacgcat cttgcttata gaaaagcgta
     2761 aggataggag gaatgaaaat ggcaactata attcttgcca gccatgggga atttgctcaa
     2821 ggattaaagc aaacagcgac aatgattatt ggagatagtg taccaattca tgccttgtca
     2881 gcatttagag atgaagatga atctattttg gtacaaataa aaaaactttt agccacaata
     2941 gatatagaag aaacctacat tttaactgat attctaggtg gtagtgtgaa taatgatatg
     3001 ctcactatta ttaaagagta tgagggattg caattaatta ctggaatgaa cttaccttta
     3061 gttatttcta ttgcaaccta taatggaaaa attggggaaa gtgagctaga aaagcttatt
     3121 aaagagagtc aacaatcagt gattgattgt agaaaattat tagtagaaca acttactgga
     3181 ggagatgacc tatgattaag ttagtacgta ttgaccatcg tttgttgcac ggacaggtag
     3241 tattttcttg gagtaaatca ttaaatatca atcgtattat tattgccaat aaagaggcag
     3301 cgaatgatga attcaaaaaa atgtctttga atttatctaa accgactggc attaaattaa
     3361 caattttttc agttgaacag ttactagaaa aaatgcctaa aatcgaaaca cttaacgaaa
     3421 atatcatgct tatttttggt aatacaaaag aaattcgtca attttgtgaa gcctatccta
     3481 aagtacaaga aatcaactat ggagggataa tcaaaaaaga aggttccaag caatttagta
     3541 atgccatttt cttgaatgaa tctgagcaag aagatgccaa aaaattaaaa gctcttggca
     3601 ttaaacaatt tattcaacag gtaccaactt ctaaaaaaga agatttgaat acaatgttat
     3661 aaaggaggaa tgaaaatgct cgttcagtca attggtttag ggttaatcgg tgttttttgt
     3721 attttagact caaggctttt aggaagaatg aattttgaac gaccgttgat tgtcagtacg
     3781 cttgttggtt tggtacttgg agacatggaa aaaggattaa ttgttggagc ctctttggaa
     3841 ttgatgtcct taggattagt aaatatcgga gctgcttcac cacctgatat gaatatggca
     3901 tcaattattg ctacagcctt tgccatttta tcaaatgcga atgcagaagc agcattaacg
     3961 attgccattc caatttcagt gttaggtcaa atactaggta tcttaatgcg gacgattttg
     4021 tcaaatttga ctcacgttgc ggatcgcttt atcgaacaag gaaaatttag ccaagcaagg
     4081 agaattcata tactttatgg ctcgggatta tatgctctca tgtattttat tcctattttt
     4141 ctagcaattt attttggaac gaatcttgtt tctcagattg ttgatgcgat tcctgagtgg
     4201 ctaacaaatg gcttaacggt tgcaagtaaa attttaccag catatgggtt tgcgttgtta
     4261 ttacaaacga tgttaacgaa aaaaatggtg ccatttttat tacttggatt tttaattact
     4321 gcttattctg gattgggaat cattggtatt gcagccttcg catgtattgt tgcgtttgtc
     4381 atggttcaag ttcaaggtaa aaactcaaat ggtaaccaaa atgagccaga tccattagat
     4441 gacttataag gaggtagatt aagtgaaaga gaaagatcaa aatgcatgga aatatcggca
     4501 gttcttatgg cgttcatggg caattcaagc ctcatggaac tatgaacgac aaatgaacat
     4561 gggttttatg tacggaattg caccaattct agataacatt tacaagaatc cagaagatga
     4621 agcaatgaag aaagaagctt acgagcggca tatgatgtac tacaactgta cccctcaaac
     4681 aagtgcattt gtgttagggt taactgcttc tatggaggag caatactacg aagaccaaga
     4741 aaactttaat ccggaatcaa tcagtgcagt gaagacttct ctgatgggac cgctatctgg
     4801 tgttggtgat tctttctttc aaggaacgat tcgggtatta gcctttggac taggaattaa
     4861 tttagcccaa caaggtagta ttttaggtcc aattctagca atgttaattt cctttgtacc
     4921 ttccttttta gttacttact atggtgggaa aattggctat aacatgggga ataaatactt
     4981 gtctaaactg tatcaagaag gtttgatgga taaagtaatg tatgtttgct ccattgtggg
     5041 gttgatggtc attggttcga tgattgccag catgatcggg attacaacac caattcaaat
     5101 gggtaaagct tttgtcttac aagatgtatt agatagtatt atgccacaat ttttaccatt
     5161 aggattaacc ttcttcatgt actggttatt gcagaaaaag gtcaaaacag gatggatgtt
     5221 ggcaatctgt ttagtcggag gaattatttt tagtttgtta ggtatcttac aataagggaa
     5281 taaccaataa atttggttga ataatataaa taaggaggaa ttcaattgat gaattcaaaa
     5341 gaaattgtta aagaaatcgt agcgaaaaaa gaggtaaaat caatcgtatt tgttggctgt
     5401 ggcgcttcaa aagcggacct ttatcctgca aagtattttc tagaccaaaa tgcgaagcag
     5461 ttacggatta gtcattacac agccagcgaa tttaactatg caacaccagc atctgtagat
     5521 gagtcaactg tcgttatttc agcttcttta ggaggtacga ctccagaaac agttgaagct
     5581 aacgcagtag ctaaagaaaa aggtgctaca gttattagtc taacacgaag cattgactca
     5641 ccgttaacaa aagatgcaga ttatgtaatt tatcatcgat ttgcagagaa ctatgctgct
     5701 aaattagaaa aaacaggcta ctgtttagaa ttggcagtag aacttttaca tcaagtagaa
     5761 ggttatgacc attatgaagc aatgcaagaa ggatttgcta ctatctatga tcttgcccaa
     5821 aaaagtgcag aatcagctcg taaagatgcg aagaaatttg ctgaacgctt taaagatgaa
     5881 aaagttattt atgtaatgag tagtggtgct acacatgaag tagcatactc aacatcaatt
     5941 tgcttgatga tggaaatgca atggattaat tctggtacct tccattcagg agaatttttc
     6001 cacggaccat tcgaaattgt ggataaagac gtaccgttta tattattaat gaatgatgga
     6061 aaaactagaa atatagatgc tcgagcatta actttccttg aacgctttga tacgaaaaca
     6121 gaagttgtag atgccttgga ttatggcttg tcttcacata ttgctaaaga agtcttagac
     6181 tactttaacc cattcgtgat tactgcagta tttagagttt atgcagaaga attgtcagaa
     6241 gcaagagaac atccattaac taagagacgt tatatgtgga aactaactta ttaaaaaata
     6301 gatcaaacta aataaggtgg cttgagaaat taagccacct tgttttcttc aatgtgattt
     6361 tatacatatg gtaaaataac tagtacatat ggtaaaataa ctagtacata ttgtgaaagc
     6421 aggtggcaag atgcagcgat taaatgacta tctttatcaa ctaacattgc ttttgaaatc
     6481 tacgccttca gataattatt cagctcgcag tatttcgcaa gctctacagt tgaatagaag
     6541 tacaatcagt agctacttaa atgaaggtgt tcgtgaaggg cttttcataa aagtaaaaag
     6601 ttacccggtt ttatttttac atagaacagc tcttgaagaa ctacatatca cactgaataa
     6661 ctccgaaata gaatcaattg aaagcttgtt aacaatttct caaaaacccg cattagatca
     6721 agtaattggc tctaaaggaa gtttgaaaga agcaattgat caaattaaaa cggcagtctt
     6781 atatcctgga aaagggttgc ctttattatt gatcggcgct agtggatcag ggaaaacctt
     6841 tctagcgaat aaaatatatg aatatgcagt agaagaaaag gtcattcaca catcggcacc
     6901 tttcatagat tataattgtg cacaatatgt gagcaatcca gagttactat cctctgcttt
     6961 atttggctac acgaaaggag catttaccgg agcaagccag gagcatactg gtttgctaga
     7021 aaaagccgat ggaggagtat tgtttttaga tgaagtgcat cgcttatctg aagaagggca
     7081 agagaaatta tttacattta tggatacggg tgaattctct cctatggggg ataatagtat
     7141 tcggaaaaaa gccgatgttc gattagtctt tgcaacaaca gaaaatatat atacgacttt
     7201 cttaccaact tttcttagga gattgccagt tattgttaat ctacctagat ttcaacaacg
     7261 tccgtcgttt gaacgtctgt cattgattga tgaatttttt gtttctgaga gccaaatttt
     7321 agctaaggaa ctatctgttt ctgatgcatt gattcatttc ttaatgaata gtgattttga
     7381 aggtaacgtg gggaatatta aaaatattat caagtatgct tgcggaaacg catatatcca
     7441 ccagaagagt cagcaaacaa ttcaagttaa attattggat atgcctttag agtacagtta
     7501 taaattcaag gagcaactaa ataaacccag aaagaaaaga gcagatcgaa tctactatcc
     7561 agaagaaaca cgacaagtgc aactagaaag aaacaatcag ctttttgttc aattttttga
     7621 ccaattactt actggattct ctgaagtgat tgaaaataac aaggatatta aactattttt
     7681 agaagaaatg gttaccaagg taacacaagt aatggatacg cttatttttc aagaggatta
     7741 cgaaaaagag cagtctttat acgccattct aaactatcat attcgtcaaa gtattgattt
     7801 tatgcgagaa agctacgggt ttgaacaaga tggtaaccgg gtagtcgctt tggccaacta
     7861 tctatatgtc aaggataatc aagtgatttt tgaaaatagt cttcaagaaa agaaaaccaa
     7921 agatcagctt aacgaatttt ttgctaatgt tcttgaaacc ccttattggt atgcaaaaaa
     7981 aatcttaagc cttttatctg agtgtttaga tcaacctgtg tatgaagagg acattttctt
     8041 tattacgcta tatttttata gtttgaatgt cacgaatgtt aaaacaggta ttaagagtat
     8101 tgtgctagct catggttatt ctacagctag tagtatggcg aatgttgcca accgtatgct
     8161 gaataagaac gtttttcaag cttatgatat gcctttagat attacattag agaaaattga
     8221 agcaaaattg attcaattcc ttggagatta tcgaacagat tcaggcttga ttttattggt
     8281 agatatgggt tcactaaacc aactaggcgg tttattagtg aatcatctaa atggaccact
     8341 gttaatcatt gatcatatca atacaccgtt attattggaa gtcggccaac aagtattaaa
     8401 caataaaagt atcaccgaaa taggagcaga aattgaaaca agtcttactt tcaaaaagca
     8461 gttactactt cccaagaaaa agaaaaagaa agccatcatt acttgttgtt atacagggat
     8521 tggtagtgcg acccagattc aggagatttt aacgaaatgc ttgaaagatg cagttagaga
     8581 attagtaatt attccgtatg attacaaaaa gctgttagaa aacaagaatt ttgagactcc
     8641 ttttcaatta tacgatgtca tcatgattgt aggtacagaa gatcccaaaa ttaatcagat
     8701 tccatatatt ggattagatc gcctgattaa tgggggaagc attggcgaat ttgttcatta
     8761 cttggaaaaa gagctgacta ttgaagtgaa cgatttacaa aaagaattaa ttttcaattt
     8821 ttcaattagt aaaattgtcg aaaatttaac cattttggat ccagataagg tgctatcttt
     8881 tgtacaaaaa gcaattaaag aattatcgaa gttattaaat tttgattttt ctaataatca
     8941 gctgtttttg ttgtaccttc actgtagttg tatgattgaa cgaattgtac gtaaagaaag
     9001 tgtggatgag caagaggaca ttgaagaata tatgcaagca aatggagaaa taatggataa
     9061 aattcatagc gctttttttg agattgaaag ggaatacaca attgaaatac cagatttaga
     9121 gttgcgatta ttgagcgata ttgttcaagg ataggagtga attcgaatga caatgggagt
     9181 aatttttgat atggatgggg tactcataga tagcgagaca ttttattttg agagaagaat
     9241 gaacttcttt caagaactgg agatagatcc aggatcaaac cagattgatg attatgtggg
     9301 gaaaacagaa gctgcaatat gggaaacatt agttcctgag gacaaatcat taagagagga
     9361 actttatccg aaatatgtag attatcgaaa aacgcatcca attgatttcg ctaaagcttt
     9421 acgaaaagaa gtgaaaccgt tacttgactt cctcaagaag cgggatatac cattggcact
     9481 ggcatcttct tctccagctg tcgagataga gagtatgctc attcaatgtg aacttactga
     9541 atatttttcc tttgttataa gtggtgagtc attaaaacaa agcaaaccac atcccgaaat
     9601 atatttaaaa gcgaaacagc aattagactg tgacttcttt attgcagtag aggattcaac
     9661 gattggtatt aaatcagcaa aggcagcaaa tatctatacg gcggcactaa aacaaccaat
     9721 gcaaatcgat cagagtgaag cagacataca aattgaaagt ctacaagaac tggaacaaat
     9781 tgttttagaa aaaggttagt gaattaatgg aaataaggct atatatctgt gctagctatt
     9841 ttgactaacc aaaaaaactt gctataattc aggtgtagta aaaggtgctg gtaacacctt
     9901 ttacgaaaat gcttcggcag tgataatggg attggctttt taagtttttt attttgttcg
     9961 caatccctaa ggtcatgtga atgatcctag ggattgctag aatattttgc aacagaacca
    10021 aaatacgaat agttatcaag cagccatatt gactgcggtc aatttaggag gggatactga
    10081 tactactgct gccgtaactg gtgctcttgc gggtattctt tacgggggtg aagtgatccc
    10141 tgaaaattgg agaaaatcgc ttcaaaatga ccagcttctt aaaacgatca gtcagagatt
    10201 ttgcgatacc gtgctatctc aaagaatttg aataatggat atgatgcaaa tcttgtttgt
    10261 actaacgttg tattgacaaa aaggatttta tttagtacaa tgttagtaca aatgatgaac
    10321 ggaggtagaa tcatgtctca atcaaccatt acatttagga ttcccgacga tgaaaaagaa
    10381 ctggtattag aatatgcaaa agcacacaat tcttcattga ccgaacttta tcgaaatgct
    10441 gtactggata aaatcgaaga tgaaatcgat ctacggactt tacggagtgc aattgaagtt
    10501 tccaaagaga aaaaagagag tggtatttct caagaggaaa tggagaaact gctaaatgaa
    10561 ttataaagtc atctacatgc cgcaagccca gaagcaatta aaaaaaatgg acagaaacca
    10621 agctaaaata attgtcgcct ggatcagaaa gaatttagaa aacacgactg acccgcgtca
    10681 gcacggaaaa ggtttgactg gaaataagag tggggaatgg cgctatcgaa ttggaaacta
    10741 tcgaatattg gctaatattt gtgattctga aattgaaatc cagatattct caattggaca
    10801 tagaagtaca atatataaaa gataaccgtt tttggaacga agtagagttt cgaaagtcaa
    10861 tgtataatct tttgaatttt gcataatacc acaggtagaa actacccgat actatcggtt
    10921 ggtttctgct tttttatggc tctttgtcaa ataggactga tagagtgaga taagaacatc
    10981 taaggtagaa ttccttttct actttagatg ttttttgatt cataggtaat cagattattt
    11041 agtaagaaaa ttctggtctt cattttccga aagcttcgaa agccataagc gactcgtttc
    11101 aatgctttga tgtgggtatg cagattttct attttggcat ttgaataagg caattcgagg
    11161 gctaaacgaa tgccggattc atagtttata aaagcttttt ttatagaatg cagttctttt
    11221 ggaacggaat tgggcatcgt tcttacaagt ttaaagaaag tgtccgcctc tttgtcgtga
    11281 aacgcttgaa gaatttcttg atagtaaaaa taggcgattc gtaattcgtc agagatcgaa
    11341 agcagacgat ccaccacttc actttcggtg agatacgccc aaccaaaatt gcgccatttg
    11401 gtccatttgt cataaacaag cttgtcctgt cgtttgatca gaagccgaga caacgccttt
    11461 aattgtcgat aatatttggc ttgtgttgga tcgtttcgat caaagctttt catgattcgt
    11521 acgcgaatat cctcaaattt acgaatgaga tgtttgacaa tgtgaaaacg atccacaacg
    11581 agttttgcct ttggaaaaca ttcctttatc agagaggcat aagaaacatt catgtccgtc
    11641 acgatgacct ttaccttcaa tcgtgcgcgt cgttcaaatt gcataaaata agaaacgaga
    11701 gcctttttct tccgtgaagg aagaatatcc agtaattttc cagtatcgcc atccatacaa
    11761 gaaaaggagt agggaccgac ttgatttttc agtgaacgaa attcatccat taataaacaa
    11821 cgcggtaacc aatttctttt tacttttgtc atggggatca gagaagcgag tgtccgagaa
    11881 acggtcgacc aagaaacgcc gcaatgctta gcaattgtcg tcattgcttg tttttcagtt
    11941 agctcttcta aaattttata gcgcacttgt ttagcgataa agcagtttct atcgacaatg
    12001 taggtattcg ccgtaaaata ggtgtggcag ccacgacagt ggtagcgttg tttcgctaaa
    12061 gcaagataag tcagttggtt cgcacattta ttaagttgaa tgagcgattt tttctttccg
    12121 ttcttaacga tcatgccttc atgattcatc tgtttacaca aaggacagcg acgaatttct
    12181 ttacttaacg tcgcagaaac aacaagactc ttgatattct taatgctctt cgattccaca
    12241 tttgtgatga aaatgttttt atctttgatt ccaagtagta gtttgatatg atgaagatca
    12301 ggcatacaga acgctccttt gattgtgttg tggtgattca attctaacgg agcttctgta
    12361 tgttttgttt tttcatgctc aaaagggacc gatagaatga ttttctatca gtcctagaaa
    12421 ttatagagcc ttttttattt ggtcttgaag aagaaa
//
LOCUS       DAXLPC010000077        12136 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.077, whole genome shotgun sequence.
ACCESSION   DAXLPC010000077 DAXLPC010000000
VERSION     DAXLPC010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.077"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..610
                     /locus_tag="ACF3UE_002108"
     CDS             <1..610
                     /locus_tag="ACF3UE_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3635488.1"
                     /translation="KRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWIQLIL
                     DEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSKITVF
                     PKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAYTIQN
                     ATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            723..1001
                     /locus_tag="ACF3UE_002109"
     CDS             723..1001
                     /locus_tag="ACF3UE_002109"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3635489.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            1119..1355
                     /gene="secG"
                     /locus_tag="ACF3UE_002110"
     CDS             1119..1355
                     /gene="secG"
                     /locus_tag="ACF3UE_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFD3635490.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            1458..2213
                     /locus_tag="ACF3UE_002111"
     CDS             1458..2213
                     /locus_tag="ACF3UE_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFD3635491.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            2216..4573
                     /gene="rnr"
                     /locus_tag="ACF3UE_002112"
     CDS             2216..4573
                     /gene="rnr"
                     /locus_tag="ACF3UE_002112"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFD3635492.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            4595..5059
                     /gene="smpB"
                     /locus_tag="ACF3UE_002113"
     CDS             4595..5059
                     /gene="smpB"
                     /locus_tag="ACF3UE_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFD3635493.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            5361..6080
                     /gene="atpB"
                     /locus_tag="ACF3UE_002114"
     CDS             5361..6080
                     /gene="atpB"
                     /locus_tag="ACF3UE_002114"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFD3635494.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            6133..6348
                     /gene="atpE"
                     /locus_tag="ACF3UE_002115"
     CDS             6133..6348
                     /gene="atpE"
                     /locus_tag="ACF3UE_002115"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFD3635495.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            6439..6963
                     /gene="atpF"
                     /locus_tag="ACF3UE_002116"
     CDS             6439..6963
                     /gene="atpF"
                     /locus_tag="ACF3UE_002116"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFD3635496.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            6950..7492
                     /locus_tag="ACF3UE_002117"
     CDS             6950..7492
                     /locus_tag="ACF3UE_002117"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFD3635497.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            7515..9071
                     /gene="atpA"
                     /locus_tag="ACF3UE_002118"
     CDS             7515..9071
                     /gene="atpA"
                     /locus_tag="ACF3UE_002118"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFD3635498.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            9085..9987
                     /locus_tag="ACF3UE_002119"
     CDS             9085..9987
                     /locus_tag="ACF3UE_002119"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFD3635499.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            10010..11416
                     /gene="atpD"
                     /locus_tag="ACF3UE_002120"
     CDS             10010..11416
                     /gene="atpD"
                     /locus_tag="ACF3UE_002120"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFD3635500.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            11430..11852
                     /locus_tag="ACF3UE_002121"
     CDS             11430..11852
                     /locus_tag="ACF3UE_002121"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFD3635501.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4036 a         2155 c         2676 g         3269 t
ORIGIN      
        1 taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg cgcacggaga
       61 aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa ttgcctggat
      121 ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg gatcaatggg
      181 agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca aaggatttat
      241 tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa gtaaaatcac
      301 tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga aatacgccgg
      361 ttactcctta aagcaagcat cagctacgag acagcttggc agcaaccatc tgcctttatt
      421 agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca cgattcaaaa
      481 tgctacggca ggggataaag cactgctgct tgttccagaa gcagaacact tggaagcatc
      541 gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac aaagaataac
      601 gatggattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat tgtttataga
      661 tctggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga ggagtgcggc
      721 atatggaaat caaagaagaa aaaaatcgtc ttgctttatt caatgatgag caacaagaga
      781 ttggagaaat gacatggtca gatgcgggcc cagacatcat gatcattgac catacatttg
      841 tagatccagc atatcgtggt caaaagttag ctgaaaagct agtgtatact ggagtagaat
      901 tagcaagacg agacgggaaa aagatcattc ctttatgccc ttatgcaaaa aaagagtttg
      961 aaaagaaacc agaatatcaa gacgtcttac gtcagtcata agaataacag ctgaaagttt
     1021 tgaactttca gctgttattc catttatata gagttgtcac ggacttttat ctatgataaa
     1081 gttaaagaga cgatatcttt tgggaaggag gctgcgatat gtataattta attttgggaa
     1141 tcgtgatcgt tttatcgatt gttatggtca ttgcgattat gatgcagcca agcaagcaaa
     1201 atagtgcagc gagtgcattt accggcggtg cggatcaact attcggcaaa caaaaagctc
     1261 gcggctttga agctgtcatg cagcgatcaa ctgcagttat gggagctatc tggatgatct
     1321 tattatttgt cctagcatat ttatcttcga agtagttgaa taagcctctc gcaaaacggc
     1381 gggcggcttt ttttattgca aagagaacgc ttaagaagaa gttatgaaag aaactatggt
     1441 aaaatgaggc gaaagaggtg agacgagtga gacaattacc aaaacccctt tatgcaaaac
     1501 atggaaagcg agcggttttg ctgcttcacg cttactcagg aagtccaaac gatgttcgaa
     1561 tgctcgcacg atttttggaa aaagcagatt atacagttta tgcgccgctt tttaaaggac
     1621 acggaacaat ggagccatat gatatcttgc aagaaaaagc agaaagctgg tgggcagaca
     1681 ctaaaaaagc catccatttt ttacagtctg agcagttttc tgatattgcc gtattaggat
     1741 tatcaatggg cggcatcttt gctgtacgag cactagaaga agaatcagtg attggcggcg
     1801 gttttttctg ttcgcctttg tctcctgtaa aaacaaacgt gcctgaaaac tttgaaaaat
     1861 acgtacgtca agtgctgaag acagcaggta aatcagagaa agaaatcaat gaaaaagcag
     1921 ttgcttaccg ctcgttagct gaacaacaat taatggatat acaagatcag gcagcaatcg
     1981 tagaaagtag gttgtcagat atccaacagc cgatattttt agctcaagct gggaaagatg
     2041 aaatgatcga ccctaatggc gtatttgaaa ctgcacgcaa gttgagccgt cagcgagtga
     2101 cacttcaatg gtatcctgaa agtggtcatg tgattacagt tggtacagca agacgcgaat
     2161 tagaaaaaga cgtcttggaa tttttagaaa aattaccttg gaatgaggaa taaatatgac
     2221 aaaagaaacg ataaaagaga aaattctctt tttcatggaa agcagtcgca aacgcagttt
     2281 ttctatggaa gaaatcgctg aaggtttagg gttccaaaaa agcgatgatt ttaaattact
     2341 agtacaaacg attgctcaaa tggaaagaga acagagtata gttttcaata aaaaaggaaa
     2401 agtgaaactt cctttaaaac caatcttgat cgaaggaaca tttcgagcaa atgaacgagg
     2461 atttggattt gtaacgattg atcccgaaga agatgacatc tatatcccaa aagaagcgac
     2521 tggttttgca atggatggag acaccgtagc aatcgatatc atgaagcgag caaatacaga
     2581 tatggatcgc ggagcagagg ggaaagtagt cgagattcga gaccgggcga ctactcagtt
     2641 agcaggggaa ttcgttgctt attcagaaga agaaatacaa gaaacagatc tttacggcgt
     2701 tgttatcccg aaagatagaa agctcaacca atttaaagta tatgcagcag cagagggagt
     2761 tcgtccagtt gacggaagta ttgtgctgat cgaactgacc cattaccctg aaaaagggta
     2821 tgcgactagt ttagaaggga taatcaagca agtgattggt cataagaatg accctggcat
     2881 ggatatcctc tcaattgtcg tggctaatgg tatccctacg aaatttcctg atgatgtatt
     2941 gtctgaagca gatgaagttc cagatcaaat cagcgaaaag gatataactg gacgtagaga
     3001 tttaagaaat cagctcattg ttacgattga tggagaagat gcaaaagatc tagatgatgc
     3061 agttacggtt aaaaaattag ataacggtaa ttattttctt ggagtacaca ttgcagatgt
     3121 ttcttactat gtgacacaag gcagtcaatt ggacagagaa gcatatgaaa gagggacaag
     3181 tgtatatttg actgatcgag tgattccgat gatcccgcaa cgtttatcga atggtatctg
     3241 ttcactgaat ccccatgttc caaggctgac catgagttgc gaaatggaga ttgatccaaa
     3301 tggacaagta gtctctcatg atattttccc aagtgtgatc caaacaacag aacggatgac
     3361 ctacacagct gtcaatcaaa tcttagaaga tcaagacgaa gaaacgatgc aacgctatgc
     3421 tcagctcgta cctatgttcc aagaaatggg tgaattgcat cgaatccttg aaacgatgcg
     3481 aatcaaacgt ggcgcgattt cttttgagga tcgcgaagcg aaaatccttg ttgatgctga
     3541 aggacaccca aatgacatcc agctaagaag cagaggaatt ggtgaacgct tgatcgaatc
     3601 tttcatgctt gcggccaatg aaacggtagc tgaacattat aataaattaa atctgccgtt
     3661 tatttaccga atccatgaac agccaaaaga agaaaaaatg cagcgcttct ttgattttgc
     3721 ttcagctttg ggcattctgg tccgaggaac gaaaggaacg atcacaccaa aagatttaca
     3781 gcatgtgatc gaaggagtag aagacaaacc agaagctgca gttatcaata ctatgttgct
     3841 aagaagcatg caacaagcac gctattcaga agacaatttt gggcattatg gcttagcggc
     3901 agattactac acacacttta catctcctat tcgacgctat cccgatctaa tcgtccatcg
     3961 tctgatccgt tcttacagtg aagataaaag tgaaagcaat caaagttcgt gggctgcgga
     4021 acttcctgaa attgcagatc atagttctaa gatggaacgt cgtgcagtag aaacagaacg
     4081 tgaagtagat tccatgaaga aagcagaatt catgatggac aaagtgggag aagaattcga
     4141 tgggatcatc agctctgttg tgaaattcgg cctgtttatc gaactgccga atacagtaga
     4201 aggattgatc catatcaatg aattgaaaca ggactacttc cattttgttg aaaatcattt
     4261 agctcttgta ggtgaaagaa ctggtctgac ttttaaaatc ggacaaaaag tgcgcgtaaa
     4321 agtagtcaaa gctgatccag atgaacgagc agtggatttt gaactcgttt ccgcagaaga
     4381 ggtcactgcg ttggaacgtc caaaagcacg caatggaaaa tctggaaaac gagaaggaaa
     4441 acaagcaggc aaacgctcag aaaaaaatgg caagaagaac aaacgatata gtgatagtaa
     4501 gcaaacgttc ggtaagaaaa aagggaaaaa gccattttac aaagatgtca aaaagaagaa
     4561 aaagaaaaaa taaaatgagt tggaggaaac agctatgcca aaaggcgagg gaaaactaat
     4621 tgcacaaaac aagaaagctc gccatgatta ttcgatcatc gacacgatgg aagcagggat
     4681 ggtcttgcaa ggaacggaga tcaagtcgat acgaaacagc cggatcaatc tgaaagatgg
     4741 atttattcgc gtccgcaacg gggaagcttt cttgcataat gttcatatca gtccttatga
     4801 acaaggaaat atttttaatc atgatccgtt gcgcacgaga aagttattat tacacaagaa
     4861 acaaatcgtt cgtcttgaaa acgaattgaa aaacactgga atcactgttg ttcctttaaa
     4921 agtctatatt cgtaacggct atgccaaggt attgattggt ctggcaaaag ggaaaaaatc
     4981 gtatgataaa cgggaagatt tgaaacgaaa agatatcgat cgacaaattg atcgaacatt
     5041 aaaaaatttc tctagataat ttcattatcc tttttcgcat attcggtgct tttgctttta
     5101 cttaatgata aaatttgtta gcatttaatc tgataaaaca tgattatcac aggttttttc
     5161 ttagatcagg agcaccgtgc atggggaaaa attcgcttcg tttttgactg aaataaaaaa
     5221 gtgtctaatt ttcatgaaaa tgttttgaat tttctgtttc atggtggtat gataccgtgt
     5281 ggttagaaac cgattggaaa aaaccagata cgcacatgaa ttgattttat gtgaatttcg
     5341 gggaaaagag gtgaaatgga ttggatgaac gctcgctaac gtttcacatt ggaccaattt
     5401 ggtttgatgg tacagtttgt ataatggtgt tactgacctg tttgattgtt ttcttcttag
     5461 cttacttttt tacaagaaat cttaagttga aaccaacagg caaacaaaat gcgatagaat
     5521 gggtcattga ttttagtcga ggaatcgtaa cagataatct gcctagaaaa gaattgagca
     5581 atttccattt gttggcattt acattgtttt tatttgtttt tgttgcaaac aacataggtt
     5641 tagtaacaaa aatcgtctta cctaacgaaa caacactttg gaaaagcccg acagcagacc
     5701 cgtttgttac tttaactttg gcatttataa tgatcttact tactcactta ttcggggtga
     5761 aaaagttagg cttcaaagga tatttcgtaa attcgttctt gaaaccctat agttttatgt
     5821 ttccgatgaa actgattgaa gaatttacaa atttattaac acttgcttta cgtctttatg
     5881 ggaatattta tgcgggggaa gttttgctaa ccttgattgc aaaaatgatg acaagcttag
     5941 gctggttctc attaccatta gcaattccat tagagatggt ctggatcgcg ttctccttgt
     6001 ttattgggag catccaagca tttgtctttg tcactttgtc aatggtttat atgagccata
     6061 agattgaagt agaagaataa tactcggtta aaaaacaaac tactatttat ctattttagg
     6121 aggaaaacaa ttatgaatta tatcgcagca gcaatcgcaa tcatgggagc agcaatcgga
     6181 gccggttatg gtaacggtca agttatctct aaaacaatcg aatcaatggc tcgccaacct
     6241 gaaatgtctg gtcaattccg tacaacaatg tttatcgggg tagctctagt tgaagctgtt
     6301 cctatcttag gggtagttat cgccttgatt ctagtttttg ccgtttaatt gaatcagtat
     6361 taaggcagaa acaacatcgt ttgttactgc ttttttacat ggaaactaga aatactccaa
     6421 agaaaggaag gctcgcctat gctgaatcaa ttggcaattg cagaagttgg caatgcgatg
     6481 ttaggtaata tcatcgttgt cagcggctca tttttgatac tactggctct cttgaagcac
     6541 tttgcttggg gaccaatcag cgatattttg aaaaaacgtg aagacaagat cgccaatgat
     6601 ttagattctg cagaacaatc tcgcatcaac tcagcgaaaa tggaacaaga acgcgaacaa
     6661 caattgttag cctctcgttc tgatgcagct gatatcatca aaaatgcgaa agaaagtgga
     6721 gaattaagcc gccaaaatat tttgaaggat gctcaagaag aagcagctcg tctaaaaagc
     6781 aaagcccaag ctgatatcac tgtagaacgt gattcagcgc tgaactctgt aaaagacgac
     6841 gttgcagaac tctctcttca aatcgcggaa aaaatcttga acaaagaatt atctccagaa
     6901 atgcatgaat cattaatcaa tcaatacatt gaaggtctag gttcttcaaa tgaaactaga
     6961 taaatataca gtaggaagac gttacgggaa agctttattt gaactggcga tcgattcaaa
     7021 tcaagcagaa gaaatctatc aagatctcgt aagtttacgt caaatctatg aacaagtacc
     7081 tggattaggg aatatgttaa gtgatgttcg tctagaacct catgaaaaac gagaaatcat
     7141 ggacaagctt gtcagcggtt atgatgggat cgttaaaaac tttttagaag ttgtttatga
     7201 gtataaccga atggatgacc ttttgttcat gatcgaagaa tatgaacgtc gatatgatga
     7261 acatcaaggg ttactattgg gaagtgtcac aacagcagtc ccactttcag acgaacaacg
     7321 aatacaatta gaaaagaatg ttgcaaaaac aatggactat caatcagttg aattaaaaca
     7381 aatcgttgat tcttctatta ttggtggcgc gattgttgaa gccaaccatc gagtaatcga
     7441 cggaagcatt cgcacgcaat tagaaaaaat gcgtaatcaa ttaaacagat agtacaaaga
     7501 ggtaggtgaa tcgaatggcc atcaaagcag aagaaattag tgccttgatt aaagaacaaa
     7561 ttgaaaatta tcaaaacgtg ctttcagtcg aagaaatcgg taccgtaact tatgtaggtg
     7621 acgggatcgc tcgtgcacat ggtttagaaa acgcgatgag tggtgagttg cttgaatttt
     7681 caaacggctc atacggaatg gcgcaaaact tagagtcaaa tgatgtaggt atcattatcc
     7741 ttggcgattt cgagtccatt cgtgaaggag ataaagtaaa acgaacaggt aagatcatgg
     7801 aagttccagt tggagaggcc ttgatcggtc gggtagtcaa tccgctaggt caaccaatcg
     7861 acggactagg tgaaatcgtt actgacaaag ctcgtccagt agaagcgatg gcaccaggtg
     7921 ttatgcaacg taaatctgtt aacgaaccaa tgcaaacagg gctaaaagcg atcgacgccc
     7981 ttgtgccaat cggacgcgga caacgtgaat tagtcatcgg tgaccgtaaa acagggaaaa
     8041 cttctattgc gatcgatacg atcatcaacc aaaaaggtca agatatgatc tgtatctatg
     8101 tagcaatcgg acaaaaagat tctacagttc gtacacaagt tgaaacattg aaaaaatatg
     8161 gcgcaatgga ttacacaatc gttgtgaatg ccggtgcgtc tcaaccagca ccattgcttt
     8221 atatcgcacc atatgctggt actgcaatgg gtgaagaatt catgtacaac ggtaaacatg
     8281 tattgatcat ttttgatgat ctttcaaaac aagctgttgc ttatcgtgaa ctttccttgc
     8341 tacttcgccg tccaccaggt cgtgaagctt atcctgggga tgttttctac ttgcactcac
     8401 gtttattaga acgtgcagca aaattaagtg atgatttagg tggcggttca atgactgcct
     8461 taccatttgt tgaaacacaa gctggagata tctctgctta tatcccaaca aacgttattt
     8521 cgatcactga tggacaaatc ttcttagaaa gcgacttgtt ctacgcaggt actcgtccag
     8581 cggttgatgc cggactatct gtatctcgtg tagggggttc tgcgcaaatc aaagcaatga
     8641 aaaaagttgc tgggacttta cgcctagact tagcaagtta ccgtgaatta gaagcattta
     8701 cacaattcgg ttctgacttg gatgcagcaa cacaagcaaa actaaatcgt ggacgccgta
     8761 cagtagaaat cttgaaacaa aaattgcatg caccgctagc tgttgaaaaa caagtagtga
     8821 ttttgtatgc tttgacacat ggattcttag atagtatccc tgtagacagt attttagact
     8881 tcgaacatga attattcgaa tatctggata ccaatcattc agatatcttt gaaacaatcc
     8941 gtacaacaaa agatcttcca gaagaagaag cgttgaacag tgcgattcag gaatataaag
     9001 acatgttctt agctacaaaa ggaagtaatt cctctacaga agataaattg aaatccattc
     9061 aaaatgcata gtgaggtgag atgaatgggt gcttcattaa atgaaatcaa gacacgtatc
     9121 gcttcaacga aaaaaacgag ccaaatcacg cgggcaatgc agatggtgtc tgcttctaag
     9181 ttgacaaaat ctgaagcttc ttcacagaag tttcaggttt atgcaacaaa agtaagagaa
     9241 atcgttacgc atttgactgc tactcagtta aatgatattg cctcagaaaa tcctagaggg
     9301 gatatcaatt acaacagcat gctgctcagc cgtcctgtga agaaaactgg ttatatcgtc
     9361 atcactgcag atggcggttt agtcggtgga tataacagct cgatattgaa acaaacgatg
     9421 tctattttag aagaagacca ccaatcaccc gatgattacg tgatgatcgc aattggcgga
     9481 actggtgcag acttctttaa agcacgcggt atcaatctag catatgagct gcgcaatcta
     9541 tctgatcagc caagctttga tgaagtccgc aaaatcgtaa atatggcaac aactatgttc
     9601 caaaacgaag tattcgatga attatacgta tgttataacc atcatatcaa ttcactaact
     9661 agtcagtttc gtgtagaaaa aatgctgcca atctcagact tagatccaga agaagcaacg
     9721 actttcgaac aagaatatat ttttgaacct tcaaaagaag aaatcttgtc tcagttattg
     9781 cctcagtatg ctgaaagttt gatctacggt gcgatcgttg acgccaaaac agcagaacat
     9841 gctgctggta tgacagcaat gaaaacagca actgataatg ctgctaatat cattgatgag
     9901 ctgacggttt cttataaccg tgcaagacaa ggggctatta cccaagaaat taccgaaatt
     9961 gttgccggag cttcggcact agaatagtat tgagattgga ggaaaaaaga tgagttcagg
    10021 caagattgtt caagtaatcg gtcccgttgt cgacgtggaa ttttctttag accaatcctt
    10081 accagatatc aacaacgcat tagttgttta taaaaatgac gaaaataaat caaaagttgt
    10141 tcttgaagca gcgttagaat taggggacgg agtgatccgg accattgcga tggaatcaac
    10201 agatggttta caaagaggaa tggaagtcat tgatacaggc aaagcaatct ctgttcctgt
    10261 aggtaaagaa acattaggtc gcgtattcaa cgtactagga gatacgatcg atttagaaac
    10321 acctttccca gaagatgcgg aaagaagcga aattcataaa aaagcaccag cctttgacga
    10381 attaagtaca agtacagaaa ttttggaaac agggatcaaa gttatcgatt tgcttgcccc
    10441 atatttaaaa ggtgggaaag tcggactatt cggtggtgcc ggtgttggta aaaccgtact
    10501 gatccaagaa ctgatccata atatcgccca agaacatggt ggtatttctg tatttaccgg
    10561 tgtaggtgaa cgtactcgtg aaggtaatga cttgtattat gaaatgaaag attcaggagt
    10621 tatcgaaaaa acagccatgg tgttcggaca aatgaacgaa ccaccaggtg cacgtatgcg
    10681 tgttgctttg actggtttga cgattgcgga atatttccgt gatgtagaag gtcaagatgt
    10741 actgttgttt atcgacaaca ttttccgttt cactcaagct ggatctgaag tatcagcctt
    10801 gttaggacgg atgccttctg cggttggtta tcaaccaaca ttggcaacag aaatgggtca
    10861 attacaagaa cgtatcacat ctacgaaaaa aggttcgatc acatcgatcc aagcaatcta
    10921 tgtgccagcc gatgactaca ctgacccggc gccggcaaca gcattcgccc atttggatgc
    10981 gacaaccaac ttggaacgta aattaacaga acaagggatt tatccagcgg tagatccatt
    11041 ggcttcttct tcaagtgctt tagcacctga aatcgtgggg gaagaacatt ataaagtagc
    11101 aacagaagtc caacacgtat tgcaacgata tcgtgaatta caagatatca ttgctatctt
    11161 aggtatggat gaattatccg atcaagaaaa agtgttagtt tctcgtgccc gcagagtcca
    11221 attcttcttg tcacaaaact ttaacgtggc tgaacaattt actggtcttc caggttcata
    11281 tgtccctgta gaagaaacag tgaaaggatt ccgcgaaatc ttggaaggca aatacgatga
    11341 tcttcctgaa gaagctttcc gaagtgttgg ccgaatcgaa gacgtcgtag aaaaagcgaa
    11401 aacactaggc tactagaaag gggtgcccca tggatcaata tttaacagta aatgtggtaa
    11461 ctcctgccgg tttggtctat gatcaccatg cagctatcgt cgttgcacgt acgacagctg
    11521 gtgagcttgg gattttgcct aaacatgcac caatcatcgt tccattgacg attgatgaag
    11581 ttcgtgtaaa acgaacagat tcagataccc acgtcgattg gatcgctgtt aatggcggaa
    11641 tcatggaagt tcgtgataat gttgtttcaa tcgttgctga tagtgcggaa cgtgaacgtg
    11701 atatcgatgt atctcgtgcg gaacgtgcaa aacaacgcgc agaacgccaa atcgaagaag
    11761 caaaagcaaa acaagatacg aacgaattga aacgggcaac tgttgcgttg caccgagcaa
    11821 tcaatcgtat caaagtatct aagcactcat aaaatgagat gcggatgttt atccgtgttt
    11881 aagaacagta aaaagaggtt atgacagaag tggtcagctt caagacataa gaaggaattt
    11941 acgaaaattg cttctcaaat ttttgtgaaa tctcagctta tttttcgaag aagctacttc
    12001 tggaacaccg tatatcagag gttgtaaaat cagcgttttg tcctgagtat tagagaaaca
    12061 aatggaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagatgat
    12121 tgaacaccgt ttattt
//
LOCUS       DAXLPC010000078        12127 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.078, whole genome shotgun sequence.
ACCESSION   DAXLPC010000078 DAXLPC010000000
VERSION     DAXLPC010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.078"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..884
                     /locus_tag="ACF3UE_002122"
     CDS             <1..884
                     /locus_tag="ACF3UE_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HFD3635502.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            932..3061
                     /locus_tag="ACF3UE_002123"
     CDS             932..3061
                     /locus_tag="ACF3UE_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HFD3635503.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3036..3725
                     /locus_tag="ACF3UE_002124"
     CDS             3036..3725
                     /locus_tag="ACF3UE_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635504.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4133..4819)
                     /locus_tag="ACF3UE_002125"
     CDS             complement(4133..4819)
                     /locus_tag="ACF3UE_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3635505.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(4955..5149)
                     /locus_tag="ACF3UE_002126"
     CDS             complement(4955..5149)
                     /locus_tag="ACF3UE_002126"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635506.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5199..5639)
                     /locus_tag="ACF3UE_002127"
     CDS             complement(5199..5639)
                     /locus_tag="ACF3UE_002127"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFD3635507.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(5643..6488)
                     /locus_tag="ACF3UE_002128"
     CDS             complement(5643..6488)
                     /locus_tag="ACF3UE_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFD3635508.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLEKQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6637..8055
                     /gene="pepV"
                     /locus_tag="ACF3UE_002129"
     CDS             6637..8055
                     /gene="pepV"
                     /locus_tag="ACF3UE_002129"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFD3635509.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(8131..9333)
                     /locus_tag="ACF3UE_002130"
     CDS             complement(8131..9333)
                     /locus_tag="ACF3UE_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635510.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
     gene            complement(9320..11107)
                     /locus_tag="ACF3UE_002131"
     CDS             complement(9320..11107)
                     /locus_tag="ACF3UE_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6020 family protein"
                     /protein_id="HFD3635511.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            complement(11120..12073)
                     /locus_tag="ACF3UE_002132"
     CDS             complement(11120..12073)
                     /locus_tag="ACF3UE_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3635512.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
BASE COUNT         3931 a         2241 c         2407 g         3548 t
ORIGIN      
        1 gtatttcagt accggttgca ctgttctcat ttatgggctc gattatggct ggaatctttg
       61 ctaatatcgt caatttcaaa caatatcaaa cgatttatgc tggtttcaat ccagcggctg
      121 aaagctatac ttataatgac tatttccaaa ttggtatgat tgggatgatt gtaagcttag
      181 ttgtggtact aacggtcgct aatatatcaa tgaacaaaaa gaaacgctat gcaatggcag
      241 caaacgtacc agctgaaggt ggcgacgcac caatgatctc atggttagcc gtattattac
      301 cagttttagg ggtcgttctt ttagatcttc aaatcatctt aggttttatt ctagcaggta
      361 tctgggcatt gctgtttact ggaaaattgc gcggaggtta taaagaaatc tgtcgtcagt
      421 ttgcgaaatt atttacagat ggcgcagtcg atgttgcacc aatggttggt ttcttgatga
      481 ccttagcgat gttcaataat tcagctgcgt atgcttctcc ttatttttca gctatttttg
      541 gagattggat accgcaatca ccattagtct tggcaatcgt atttgctata ttgacaccac
      601 taggattttt ccgcggtcca atgaatctag tcggttcagg ctcagctatt ttagctgtcg
      661 tgttagctgt taatccaacg atgtcgccag cctttttgtt cccgttattt gcaattacaa
      721 cgattgctcc tcagcattta gatattacac aatcttgggt tgcttgggga ttaggttata
      781 caaaagtaac ttctcgagaa tatatgaaga aatccatccc aactggttgg atcatcggtg
      841 cgatcttatg cctgatcacg ttcttattgt acgggaacgc ctagtaaaca aaacgtcgat
      901 aaaaacgatt agataaatgg aggaaaagaa aatgaaacgt tttgtgcgaa tgggaattga
      961 tgttggcggt acacatacga aagcagtcgc aatcgataat gcgacgcacg aaatcatcgg
     1021 aaaatcttca gtgaaaacaa cccacgatga tgtccgtgga gtagctgcag gtgtcgttca
     1081 gtcttttcaa aattgtttgc gggaaaataa tatcagtcca gaagatgttg tgtttgttgc
     1141 acattctacc acacaagcga ctaatgcact gattgaagga gacgtagcaa aagtcggcgt
     1201 aatcgggatg gcaaaaggtg gattagaagg ttttttagca aaacgacaaa ctagattgaa
     1261 cgatatcgat ttagggaata agaaaaaaat agagattgtc aatgcattct tacctgtcaa
     1321 aaacttaaat gtagaccgtg tttcagaaac gatttcttct ttagaaagag aaagagcgga
     1381 ggtcttggtt tcttctatgg catttggagt agataatggg gaaccagaac gagttgttta
     1441 tgaagcagca tctgtgaaag cgatccctac aacgatggct tctgacatca caaaattata
     1501 tggattgaca agaagaactc ggacagcagc aatcaacgca tctattttac caaaaatgct
     1561 agatacggca acctcgacag aagactccgt acgagaagca ggggtcaatg tttctttgat
     1621 gattatgcgc ggagacggcg gagtaatgga aatcaatgaa atgaaaaaac gacctgtttt
     1681 aaccatgctt tccggtcctg ctgcatcagt catgggctct ttgatgtact tgagagcgtc
     1741 taatggtgtt tattttgaag taggcggaac aacaaccaat atcggggtca ttaaaaatgg
     1801 acgtccagca atcgattatt caattgtagg tggccaccca acatatatct cttcattaga
     1861 tgttcgggtt ctaggtgtgg caggcggttc gatggtacgg gctaatcagt caggaatcat
     1921 cgatgtcggt ccacgttctg cacatattgc cggtctagat tatgcagtat ttacggagac
     1981 agaaaaaatc aaaggtccta aggttgaatt tttctctcct aaagaaggag accctgctga
     2041 ttacgtcaag gtagtgatgg aagacggaga agaagtgact attacaaata catgtgcagc
     2101 caatgttctt ggattagtgc aagaagaaca tttttcttat ggaaatgtcc catctgcacg
     2161 aaaagccata caggcattag cagactattg tcatacgacg gttgaagaca tcgcagagca
     2221 gatcatggaa aaatcctatg ctaagattga accggtgatt ttagaattgg cagacaagta
     2281 tcacttggag aaagatcaga tttctcttgt aggtgtaggg ggcggcgctg cctcattgat
     2341 tacttacttt agtaataaaa tgggtgtgaa atattcgatt cctgaaaacg ccgaagtgat
     2401 ttcttctatt ggtgtagcac ttgcaatggt ccgagatgtt gtagaacgta tcatcccttc
     2461 gccaagtaaa gaagatatac gatcgttgaa aaatgaagcg atgaataaag cgattgaatc
     2521 aggcgctaca ccagaatcga tcgaagtcca cgtagaaatc gatccacata cttcaaaagt
     2581 aacggctatc gctactggtt ctacggaagt gaaagcaacc gatctaacca aggagatcac
     2641 aacagaagaa gcactagagc ttgctgcaga ggatatgcga ttaaataaaa atgaagtttg
     2701 cttattggaa aatacacctt tcttttatgt atgcggcgaa cagaatcgtt caaaaaatgc
     2761 tggaagtctt cggatcatcg atcaaaaagg atttatcaag gtccaacgtg gacatgcttc
     2821 atgtatgaaa acaactgcag ccaattatat gacagctgtc gaacaacttt gggaagatat
     2881 ggcagtttat caaactgaat tgattgcccg accagaattt tatctctgct taggagcaag
     2941 agtctctgat tttacagcga cggatctgga acaactacag cttttgatgg atctggaagt
     3001 atctactatg gaaccggagg aagaagtgat cgtcgttgcc ggaaatatca aacaaacata
     3061 agttagaaga gttactaaac gaattacaac agatccccga agaaatttgg ggattctacc
     3121 agtttcggcg agatttattt tggaaaaaga ttcctttgtc caagcagaaa attcttatac
     3181 aacaatcaat cgattgtggt atcgaaacgg catgtagcat caaaaaaaag tacccttttg
     3241 ccgatgtagg agaaatctgt gaacaaatgg ctgttccaat cgtttcctgt gaatcagagc
     3301 aaataaacga acgaatcact tttgcaactt atgcagaaga tgaagggatc cgattgatga
     3361 cggagccgtt agaaaaatta aaatgttcag gactagcttc gatctctaaa gaaacagcgc
     3421 aagctttgat tattggacat gaactatttc accacatcga agcttctgtt aagggaattt
     3481 atacgcaaag cgaaaaaatt gtgctgtggc ggttgccttt ttatacacat caatcaaaca
     3541 ttcgtgcatt gagcgagata gcagcgatga gtttttcaaa agagatgaat caaagcgatt
     3601 tttcgcctta tgtattagag gcagtcttac tttggccata taatgaaatt cgtagccaag
     3661 ggatcttaga agaaataaaa gaaatagaaa aaagatgtac ggagtatgat ttagattaca
     3721 aataaagaga ctgtgacaaa agtcgtgtca cagtcctttt tttccgaata aacggtgttc
     3781 tcctgtcaac tcctcggtca caagtcaaaa tattcaacaa acatgagaag ctgttttttg
     3841 aaattgttcc ttgtgactcg gagatgaacg gcaggctcac gacctcttgg aaaaaggtgt
     3901 tcaaaagctt gcatctgcgg taataagaac agccaagtta aaaacataag aagctatttt
     3961 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct caataaacgg
     4021 tgtgcaatca gctgaccctc ggtattagct caaaaaaaac ggcaaaatat gaggaactat
     4081 tttgccgttt atttctctaa tactcaggtc aaaacgctga ttccaaaacc tcttatttga
     4141 tgggtctgtc ctgaatatct tcaaaataat cggggtaatt atgaatcacg tattcttgct
     4201 cctcgataat catatgtaaa tgcatcgtgc aaagaaatcc gacttcatca aagttatgat
     4261 caatcattga ttgaagcatt gtctgatgtt catctaatac tcgaccccag tctaattctg
     4321 aaatcgtcaa acgtaaccat ctgaaacggt tcaagtgcgt actataactt tctagccaat
     4381 cccaaatttc tcgttttcca gcaatttcat aacaagttcg gtgaaaatca gtatccaaat
     4441 caaaaaaagc ttttttattt tgagcgatca ctgcctgatc ggtttgttct agtatttttt
     4501 ctagtttagc ttgatcttgc ttggtcattt tcgcactgca ttcttgcagg atcggttttt
     4561 ccaacttttc ccgcgtataa cgggctaatg aagcagatcg gatatcgatt tttgaaacat
     4621 aagtgccgga ctgtggaatg gtttttacaa gctcttgatt gcgcagttgg atcagtgctt
     4681 ctcgaatcgg tgtacgcccg atagctagtt gttcttctaa cactttatcg gagattttac
     4741 ttccaggtgc taactcggaa taaatgattt gtttacgtat agattcataa gcttgctgtt
     4801 gcaaattatt gataaccatt taaccttcct ttctatgcag atataatcta ttataacata
     4861 aatcgcttac aaatcgtgtg ggcataaaaa cacagtctgc aaaaaaagcc ctgataggca
     4921 tgcctattag agcctcgaaa agaaaaatat tgaatcaatc tggtcgtacc tcttggatcg
     4981 gtttgacacg accgccgatt cttttagcaa aagcttcgga ttcttttttg tctttgaaaa
     5041 tgagcagatt gtctaagttt ttttcccgag tgcgacagcc agttttatcg atgtaaccgt
     5101 gcattacttt aacgacatac atggggatca cctgcttttt tcttttcatt atacgaacta
     5161 ctcgacacaa tacaagaaaa atgcttagac ggtctttatt aagaatttac atcatccaaa
     5221 gaagcgtacg cttggaataa ctgttctaac tccggattga ctttgctcag cttcactaat
     5281 cgttgcgaat cagaaagtaa aaaacagtgt ttactactgc cagtagtttt taattttttg
     5341 tcttcagttc ccacaatttc gtagctaaaa tccaaccgtg ttcccgtata cttttggata
     5401 gttgggtgga tgctcacttt ttctccgtaa tggatcattt ctttatagct gcaatttact
     5461 tccagaacgg ggatgatgat cccagattct tcgatttttt tatagggaaa ccctagatgt
     5521 accaataagg ctacccgagc ctcttcaaac cagcggatat aattgctgtg atgaataatc
     5581 cccatttgat ctgtttcata ataaaaaggt tctcgcacat aacctgtaaa tttctccatg
     5641 actcatgcct cgttttccat tgatttttta caaaaataat tcatccactt cggaagtgct
     5701 tcgctgattt gtgtcggcaa aacaatatat tgttcttttg ccagctggtc tccaatgaaa
     5761 ctatgaagat aaacagctgc tgcaatcgtt tggtcatttt gaggaaactg ggctaaaaat
     5821 cctgtgatca tcccagctaa agtgtcaccc atgccgcctg ttgccatagc agcagaacct
     5881 aaaggattgg tgtagaagtg ctggtgacca taaatttttg tctcatgact tttcaaaacg
     5941 agcacagcac cgatttcctg ttgcttcttt ttgttttctt tatcccgttg ttcttgtatc
     6001 ggtagagaac tcaaccgttg ccactccatt tgatgaggtg taagtacagt ttgttcggga
     6061 tagggtagca aaagatgatt agcaacaagt aaacttaaag cagagccatc aatcaccagc
     6121 cattgttctt ttgattgttt ttctagtact tgtttgaaac gttccaaact cttagaagaa
     6181 gtacccaatc cgggaccaat caagagtaca tctgcttgct ttattacgga aagaaactgg
     6241 tcagtatccg tccaatctac aatcattgct tctggcagat gactgtgaag agcactccga
     6301 tttttttcat cagttactac agtcgtgaga cccgctccac tgtgtacggc agctaaagca
     6361 ctcataatga ttgctccgcc atattgttca ttgccgccaa tcaaaacgat acgtccaaat
     6421 gttcctttat gtgaaatctt tggacgaggt gtgatgactc ttttcactag ttgttcgttt
     6481 atcagcatcg aaaaacctcc ttttactcat tatagcgtat atttttttta gagaaaaaca
     6541 gataagaaaa ggaattgtca gattttttga actatttttt tctgtaattt gtggtatcat
     6601 gaacacgaag acttaaataa gtggaggatt aactttatga caattgattg gcaaaaagaa
     6661 gtagaagcac gtaaagaaga cttgcttgaa gacttgaaaa atcttttacg tgtcaacagc
     6721 gagcgcgatg attcaaaagt aacaccagat gcaccatttg gacctggacc tcgcgacgca
     6781 ttgaaacata tgttagctta tggcgaacgt gatggattta aagtaaaaaa tgtcgataac
     6841 tatgcagggc atattgatct tggcgaagga gacgaaacgc tagggatatt tggacacatg
     6901 gatgtcgttc ctgcaggaga tggctgggac acagatcctt atgaaccagt aatcaaggat
     6961 ggaaagatct ttgcacgcgg atcaagcgat gacaaaggtc caagtatggc agcttactat
     7021 gcgatgaaga tcattaaaga acttgacttg aaactatcaa aaaaagttcg cttcgtagtc
     7081 ggcagcgatg aagaaagcgg ctggggcgat atggcttatt atttcgaaca tgaagaagaa
     7141 ccagattttg gtttctcacc agatgctgaa ttcccaatca tcaatggtga aaaaggaaat
     7201 gtttctttag ctttacgctt caaaggcgac aatgcaggag attatgtctt gaaatctttt
     7261 gtttccggac ttcgcgaaaa tatggtgcca ggaacagcaa ctgcagcact tcaagtacca
     7321 agtgcagatg cagctatcgc gatggaagaa gcattttacc aattcatcga agcaaatcca
     7381 gtaagcggaa cgattgaagc ggacaatacg tatgtaaaaa tcgaattagt tggtaaaggc
     7441 gcacatggtg caagcccaca atctggtatc aatgcaggtt ctttcttggc attgttctta
     7501 gataactatg aattcctagg atctgctaaa caatttatcc atgtagcagc tgcttatgtc
     7561 catgaagatt tttatggaga aaaactagga gtcgcttatg aagatgaaaa aatgggcaaa
     7621 ttgacaatga atgctggact atttgctttt gaagaaaatg gtacagagga agcgaacttc
     7681 atcaatatga atttccgttt tccaaaaggt gtaacagtag acggattgca aagtgacatc
     7741 gaacaaacag tggggcaaga aggcgcaaca gttactcgag gtgctcgcgt aatggaacca
     7801 cattacgtac caatggatga tccattggtg gctacattat tgcaagtcta tgaagaccac
     7861 actggagaaa aaggctacga acaaatcatc ggtggcggaa cttacggacg tttgttgaaa
     7921 cgtggcgttg cttatggagc gatgttccca ggatatactg atacaatgca tcaagcaaac
     7981 gaatttatga gtcttgatga cttgttcaga gcaacagcaa tctatgcaga tgccatctat
     8041 cgtttggcga aataaaaata ctaaaaaact ccggctatct ctgacagctg gagtttttat
     8101 gtttaaaaat gaattagtac atcggtattc ttaaaagtaa tttagttcgt cttttgattt
     8161 ctcaggaggg atcaaaaagg cgaaagcact aagtatagca aaacttgtga tgatttgcgt
     8221 acgatacgta aaccaataat gaatctgtga gtgattagct aaaatattgt accaaatata
     8281 cggcgttaca gcagctaaaa caaacaaaac tagaagttgg aacggacgcc agctatttcg
     8341 tttacgataa gcaaaataga gaaaaacaag acaagtaatc aatagcaata atattgctac
     8401 ttttggatac atcaatctaa tattgctttt cagcatctct aatcgatgca acgggtattt
     8461 gtcgtttcct tccgttcgaa agaggatttg gttgattgca tcttttacaa tgtttttgtt
     8521 caatatgatc gatgatagga tccatttagc cacccatgtc aaaccatagc ctaatcccca
     8581 aaagataccg gtaaaaacaa aactgcctac ttgtttgctc aatgaactgc gtttatccat
     8641 taaatactta tttgttacat aataaataat gatcacaggt atcccccaag agatgaccgg
     8701 tgttgtcaac aagtcaaaaa agttagctaa agaaccaatg acaaagaaat acaagaataa
     8761 ttgttggttg gtgttggaga gttgtggttt tgttaaaaat agtaatacag acaataaagt
     8821 caaaatccaa atatttgaaa attgcatact gaagaaaaag gttgcagcat ttcctatagc
     8881 aagcgaaatc aacaaggctg tcgttaaata gatgtcgcta cacttggtta aaaagtagct
     8941 cgtcaatcca atcagcagaa aaagaatggc tgcgtaaatc attcgaatac tccccaaact
     9001 catccctagc agtaaaggtc gtaaaaaaag ctgataacca tgccaataac ggggataatc
     9061 cgccatagac atcgcgttct ccaaggagtt caattcagga tctgcttttg tttttcgtat
     9121 catcaaatga tcagtaaaat tatctaaccg agtgcctagc atatttcctt gattgataga
     9181 aggatacatt ccttcttttt caaccatctg tagagatttt tctgcattcg attcaataga
     9241 gtgctgcgga atgaaaaaag taattgtcag tagtacgcaa tagctagcga tcaagagaac
     9301 aaaagcaaaa aatatctttt taaatagttt catgagtatc tcctatatct gttttcattt
     9361 tttctctttt atctagtaaa aaaggagaga ggatataaac aggtagacct aatgctaaaa
     9421 caaacacata ccgtaaacta aaagccacag gagtagcaat cataatagta gcaaaaacaa
     9481 gcataccggg aagaaaaagg agtaaatacc gatatttttt cttaaagatt gctaaaagtg
     9541 cactgccgat agctaaccac agtaatgtgc cggaaccaaa gaaatcacga gcatcgatga
     9601 tttttttcat tcctgacaat ccagtaagat gttcaatcaa atctacttgc ttcatcccat
     9661 aattattcgt gtttacacga gtatctaaaa agccgtaact attttttgta ccaggtaccc
     9721 agaacccgaa cgtttctaaa atataagcat ctgtatagat ttttatatta cttggtaaat
     9781 ttcttgccca tagtgataga aattcttttt tatgtgtatt caaaaactca ttgttaaaat
     9841 ttttatgcca cttgattgag tctgcaagac taggagaata cgcttcataa tcttttatcg
     9901 ggagtagctg attcatgaat gctttatctt tcttagacaa gtcaccatcc ataacaatag
     9961 ttctagaaat ttgctgcaaa ggaacaccta attgttcagc agtttctgta ggaatagcat
    10021 aacgagccat caacgggtgg atgagtagtc cagcaatcac tgtataaccc agcaccactt
    10081 gaaagaatgc ttgatacctt ttttgtttca aaataatcaa gccgcaaatc aaacctgtgc
    10141 cggttactac ataaatccca ttatttctta gataggtggt cagtaaagca aggatgatta
    10201 cgtaaatctg attgagaatc gttggctttt ctcgttgaaa aataaagtca aaaaccgcta
    10261 aggaaaataa aaagcaagcg atagagaaca aagtatcttt ttgcatgttc aaggcgtaga
    10321 ttggaaaaac cggtgcaaat gcaaaatagc ataaactaat gagtaccgga aaaaaatgga
    10381 tgtttctttt taacagccag caaagagaat aacttatcgc tgaagctgtt atcaatgttt
    10441 gaaaaatcga aaataaaaat acaccgtgat tgatcgtatc agttggtaaa tcatgaacaa
    10501 atagcttgac cagtaaggtg aataagactg gatgatgatt gcttatagga acatcaccca
    10561 tagattgggc gaccgaactt aacgaatcag gcaaaaccac tccaggatac aatgccaaca
    10621 gataaggaag ccaacacaga actaaaaaga cagtaaagaa taaaaaatat tttcttgaag
    10681 agaaagcctg tgtgttttga gcagtaaaaa atgtttccag ttttggcatt gataaataaa
    10741 tcgattgtaa aaataaaaaa gaatacacaa aaatggagaa ataaacaaga aagtaaaaaa
    10801 tacttccatc agcaatcgtt gtctttgtat agtttgctga gacatactga aattgtatct
    10861 gtctgccaat agaaagtgta agagcaaaag ctgcagaaaa aaacaatcgg gcaatagctg
    10921 caactttgtt ttttattgaa aacaactcta ttccatattg cttaaaagca agtagcaaaa
    10981 ccatggctaa accaatgatt actgttggat tcaaagttcc tagaccataa gaagtaaaaa
    11041 aagcaaaacc tgacgcaaat aaagttgcaa aaaaagtagg aaatagattc tcctttttct
    11101 tatgcataaa aaaggcctcc tacttcattt ctttattttg atattcgtgg tagacatggt
    11161 ataaattcaa ttcatattct ttcttggcat ttgtgacgac cgtatccaaa atcaaccctg
    11221 ttactaatga aagaagggct aaagtcatca atccagtact taaaatcgca gaagggatgc
    11281 gtgtaataaa gcttgtcagc atatattcac gaatcacagg aatccccatg accaatccaa
    11341 ataaaaagaa gaagatggtc cagatcccaa agaaaagcaa aggtttataa tctttgcaca
    11401 ttttgatgat catcatgatc actttgaatc cgtcagagaa tgtattcaat tttgattcgc
    11461 taccttcagg acgatcgcga taatcgattg gaatctcaac gaacttgaat tttttatcta
    11521 aagcatgaat cgtcaattct gtttcgattt gaaaaccaga actcataata gggaagcttt
    11581 tgacaaaaat tcgattgaat cctcgatagc cggtcatgac atcgcgaatt tttgttttat
    11641 ataagtaagt aattgtattt ttaaccagat tattcccaaa atcatggaaa ggacgcttat
    11701 tttcatcaaa ataggttcca tttgatagac gatcgccaat gaccatatct gcttcgccag
    11761 aacgtaattt ctcaagcaaa ccatgtgcag cttctgcagg ataagtatca tcaccatcta
    11821 ccatcaaata ataatcggca tcaatatcaa aaaacatttg acggattaca tttccttttc
    11881 cttgacgtgg ttctttcttt acgattgccc caccttgaac ggccaattcg tatgttcgat
    11941 cggtcgaatt attatcatag acataaatat ctgcttctgg taattccctt ttaaaatctt
    12001 caataacagt tgaaattgtc gcctcttcgt tataacaagg aatgagcacg gcaatttttt
    12061 cacgtgattc catttgtcac tctccttata taataaaact aatcttattt caagaatacc
    12121 atataat
//
LOCUS       DAXLPC010000079        12091 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.079, whole genome shotgun sequence.
ACCESSION   DAXLPC010000079 DAXLPC010000000
VERSION     DAXLPC010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.079"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(32..589)
                     /gene="frr"
                     /locus_tag="ACF3UE_002133"
     CDS             complement(32..589)
                     /gene="frr"
                     /locus_tag="ACF3UE_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFD3635513.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(592..1314)
                     /gene="pyrH"
                     /locus_tag="ACF3UE_002134"
     CDS             complement(592..1314)
                     /gene="pyrH"
                     /locus_tag="ACF3UE_002134"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFD3635514.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1450..2331)
                     /gene="tsf"
                     /locus_tag="ACF3UE_002135"
     CDS             complement(1450..2331)
                     /gene="tsf"
                     /locus_tag="ACF3UE_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFD3635515.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2430..3212)
                     /gene="rpsB"
                     /locus_tag="ACF3UE_002136"
     CDS             complement(2430..3212)
                     /gene="rpsB"
                     /locus_tag="ACF3UE_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFD3635516.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3571..4050
                     /locus_tag="ACF3UE_002137"
     CDS             3571..4050
                     /locus_tag="ACF3UE_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFD3635517.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4267..5358
                     /gene="phnW"
                     /locus_tag="ACF3UE_002138"
     CDS             4267..5358
                     /gene="phnW"
                     /locus_tag="ACF3UE_002138"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFD3635518.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKELLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5351..5479
                     /locus_tag="ACF3UE_002139"
     CDS             5351..5479
                     /locus_tag="ACF3UE_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFD3635519.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5483..6028
                     /locus_tag="ACF3UE_002140"
     CDS             5483..6028
                     /locus_tag="ACF3UE_002140"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HFD3635520.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6482..8173)
                     /gene="argS"
                     /locus_tag="ACF3UE_002141"
     CDS             complement(6482..8173)
                     /gene="argS"
                     /locus_tag="ACF3UE_002141"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFD3635521.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8593..9540)
                     /gene="arcC"
                     /locus_tag="ACF3UE_002142"
     CDS             complement(8593..9540)
                     /gene="arcC"
                     /locus_tag="ACF3UE_002142"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFD3635522.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9655..10674)
                     /gene="argF"
                     /locus_tag="ACF3UE_002143"
     CDS             complement(9655..10674)
                     /gene="argF"
                     /locus_tag="ACF3UE_002143"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFD3635523.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10765..11994)
                     /gene="arcA"
                     /locus_tag="ACF3UE_002144"
     CDS             complement(10765..11994)
                     /gene="arcA"
                     /locus_tag="ACF3UE_002144"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFD3635524.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3293 a         2521 c         2194 g         4083 t
ORIGIN      
        1 aatgatccgc ccctctgttt ttatgatttt attaaacttc caataattct ttttctttat
       61 cagcagcgat cttatctact tctttgatgc tgttatctgt caatgtttgt acgtcttttt
      121 ctaatccgcg caaatcatct tcggtaatat caccattttt ttgttgtttt ttatattcat
      181 cgatcgcatc acgacggatg ttacgaatcg cgatttttgc attttctgct tcttttttaa
      241 catctttagc taattctttt ctgcgttctt ctgtcagttg cgggataact aagcgaatga
      301 catttccatc attggttgga ctgattccga tatcacttgc cataatagct ttttcaacat
      361 cttgaagaat gctcttgtca aaaggtgtga tcattaaaac acgtgcttct ggaatttgga
      421 ttgatgccat ttggttcaat ggtgttggcg caccgtagta gttcacagta atacggtcca
      481 aaaggctagc gttcgcacgg cctgcgcgga tttgcccaag ttcacgttga agattttgtg
      541 ctgctttttt cattttttct tttgcttctg tcataattgc atctgccatt tttatttccc
      601 ccttacagtt gttccgatat tttcgcctaa gattgcacgg cgaatatttc cgtgttcatt
      661 taaattgaag acaagcagtg gaatatcatt atccatgctt agtgaacttg cagttgaatc
      721 catgacttgt aatcctttgg caataacttc cagatgagtc agttcttcaa attttactgc
      781 atttgcatct actttcggat cagcagaata aacaccgtct acattgtttt tagccatcag
      841 gataacatct gcgccgattt ctgccgcgcg taatgctgct gttgtgtctg tcgagaagta
      901 cgggttgccg gtaccgcctg caaagataac gatccgtcct ttttctaaat gacgttctgc
      961 tttacggcga atatatggct ctgcgatttg acgcatttca atcgaagttt gcacgcgtgt
     1021 cggtacaccc acgttttcca acgtatcctg taaagctaag gcattcataa ctgtagctaa
     1081 catacccatg taatcagctt gagcacgttc catgcccatt tgtgctccga tttgtccgcg
     1141 ccagatattt ccgccgccca caacgattgc catttcaacg cccagctcgt gaacttcttt
     1201 gatttcttgg atgatttctt tgattactgg tggtttgatt ccaaatcctg cgtccccagc
     1261 taaagcttct ccactcaatt ttaagactac acgctgatat ttcggtgtga ccatgttcat
     1321 tcctccaata ttttctattg ccattttacc atacttagat gatttcgaca ctctaagact
     1381 ggtttttctt gttttgctta aaaaaaggga gcgcacaaac cgtgcgttcc cgtctgttat
     1441 tcaacagaat tattttttca cttggctcat aacttcttct acaaagttat cttcgcgttt
     1501 ttcgatacct tcgccaactt cgaaacgtac gaatgtttta acagttgcgc cttttgatgc
     1561 aacgtatttt tcaacagtca tatcaggatc tttaacgaat ggttggtcca ccaaagcgat
     1621 ttctgctttg aatttcttca agcgtccttc taccattttt tcaacgatat tcgctggttt
     1681 gccttcgttc aatgcttgtt ctgtaagaac agttttttca tgttctaatt cagcttctgg
     1741 aatttgtgat tcgtttacat aacgaggatt gatagctgct acgtgcatag ctacgtctct
     1801 tgcaactgtt tcgtcagttg ttccatctag aacagtcaat acggcaatac gtccgcccat
     1861 atgcaagtat ccaccaaatg cagcattgtc gtctttttct acaacttcaa agcgacggaa
     1921 gctgattttt tctccgataa cttgagttgc ttcgatcaag tcagattcaa ttgtaccttt
     1981 atctgttttg attttcattg cagcttccat gtctgctggt ttgttttcag caacaagttc
     2041 tgcaatttct tttactaaat cttggaacat ttcgttttta gaaacaaagt ctgtttctga
     2101 gtttacttca acgattgctg cagtgttacc tttcacagca actgaagcca atccttcagc
     2161 tgcaatgcgg tcatttttct tcgcagcctt tgccattcct ttttcacgta aaagatcaac
     2221 tgctttttcc atgtcgcctt ctacttcaac taatgctttt ttcgcatcca tcattcctac
     2281 gccagtcatt tcgcgtagtt cttttaccat tttagctgta acgtctgcca tgtttaactc
     2341 ctcctgtgtg tttttctttt taaaaaaagc tgcttcaaag gagagtgagg cttgtcgccc
     2401 agcctttgaa acagctccat cattcaaaat tattctgctg aagaattgtc gccttcaaca
     2461 acatctacga tttcttcgat tgatgttgct gtgttttctt ctgtgaaatc ttcttcaact
     2521 acttgatctt caccttggtt tccttcgatg aaagcatcag ccatttttga agtaatcaat
     2581 ttaacggcac gaattgcatc gtcgtttgaa gggattacta cgtcgatttc atctggatcg
     2641 cagtttgtat caaccatagc tacgattggg atatttaatt tgtgtgcttc ttgaacagca
     2701 atacgttctt tacgtgggtc aacgatgtac attacatctg ggattcttgg catatcagcg
     2761 ataccgccta agaatttttc aagacgttca cgttctttgt tcaaaccagc aacttctttt
     2821 ttaggtagaa cttcaaaagt tccatcttct tccattgcat tgatttgttt caaacggctg
     2881 atacgttttt ggatagtatc ccagtttgtc aatgttccgc ctaaccaacg atggttaacg
     2941 aagtattgtc ctgcacgagt tgcttcttct ttgattgctt cttgtgcttg tttttttgta
     3001 cctacgaata atgctacgcc gccttcttca gcaacgctct tcatgtaatc ataagctgca
     3061 tctactaatt taactgtttt ttgcaagtca atgatgtaga ttccgtttct ttctgtgaag
     3121 atatatttct tcatttttgg attccagcga cgagtttggt gaccaaagtg tacgccggct
     3181 tctagtaatt gtttcataga aattactgcc atgtttgttt cctccgattt ggttttattt
     3241 ttcctcttct tatcttctac cttgccggca aactttttca agcacctacc gacaatccaa
     3301 taagaatgtg gatttgctga tgcataaagc accctcagct attatacaga caaaagatcc
     3361 gtatcgcaag agcaaatata cttttctgct caacattcaa tagtttacct gaaagataaa
     3421 aagaattcaa gaaaaacagt agatttctct ttgtttcttt attatccttt ttccataaaa
     3481 taattttagg tataaaagac gaatattatt gggcaatcct tctttttttt gttatgatac
     3541 atgtgaaatc tttcgtaaag gagaaagaaa atgcgcaaag ctcaaagaca tttgctgatt
     3601 aaacaagtca ttgaagaatt cccgatccgt acgcaagaag aactattaaa caaacttggg
     3661 cattatggcg ttaccgccac gcaggcaacg atttctcgag atatccgtga tctaaaaatc
     3721 gtgaaggcac ctgatgaaaa tggcgtttcc cgcttcgtat tgtttcgcga aaaaggaact
     3781 cctgagacta ggactgagga agaggatcgg ctggttcaaa tgattgaaga cattgtattg
     3841 aaagtcgaac gagtccactt tttgacgatc gtcaatacct tgccagacaa tgctcattta
     3901 tttgcatctg ttttagatga gatcaaacct ccctctattg tcagtacaat tgctggattc
     3961 gatacgatca tggtcatctc ggaaaatgag gaggacgcaa aacgagtaga agaatttctt
     4021 caccatccaa ctgaagtatc acttttttaa tcagagcacg tattcctaat atggaatgcg
     4081 tgttttttta ttttcaatat tttccttatt gaataaacct ttacactctt tacaaaaata
     4141 catcattttt tattcaaatt tttcaacacc ttgattgaat cacaataatc atcatttata
     4201 ttggatgtta acaagagcag cttcttgctc tttgtgtatt tcaaaaaaga aatgaaagga
     4261 aatcatatgt ataaattatt aacttctgga ccattgacga cttctgaaac agtgaaaaat
     4321 gctatgctga tcgatcattg tacttgggat caagaataca aagaaattac acaatggata
     4381 agaaaagaat tattggatct tgctcaagta tcggaaggaa tatacacaac ggtcttaatg
     4441 caaggtagca gctccttcgg ggtagaatcg gtattaagtt ctgtgatcag gccagaagat
     4501 actgtactga tttgttcaaa cggcgcatat agacaacgaa tgatcaacat gtgcgaatgt
     4561 ctgaaactga actataccgt ttatgaggta tcggaacatc aaatcctcca agctcatgtg
     4621 attacacagc tgattgaaga gaatccgtct atctccgcac tagcaatggt ccatagcgag
     4681 actacttccg gtattttgaa taatttggaa gagattgctg ctgtcacgca agaaagagat
     4741 cttttgttta tagtggacgc gatgtcaagc tttggtggga taccgatttg tgtagccgaa
     4801 ctagggattg attttttgat ttccagctca aacaaatgta ttcaaggtgt tccaggcttt
     4861 tcttttgtac ttgctaataa agcggaactg gaaaaacgaa aaaatgttag ccgaagtttg
     4921 tcacttgatc tatatgacca gtaccgcgtg atggaaaacg agaatggcaa atggcgtttc
     4981 acttccccta cccatacggt tttggctttt caacaagcgc tgaaggaact agaggcagaa
     5041 ggaggaatcg aaactcgata ttcacgttat ctcgccaata atcatgtgct acgacaaaaa
     5101 atgacagaga tggggttcca gcctttcatt caagaatatc aggggccatt catcacctct
     5161 tttctttacc ctaaggactg gcgatttgat tttaatcatt tttatcagta tttaaagcaa
     5221 aatggatttg tgatctatcc cgggaaaatc agcgatcatg aatgttttcg tatcggaaat
     5281 attggcgaga tctatccgga agatattttg gaactgacag caattatcaa agactataag
     5341 gagaacgtta atgattaaaa ctgtaatttt tgattgggca ggaacaactg tggactttgg
     5401 ctgtatggct cctgtccacg cttttagaaa tgcttttcta gaaaaaggaa tccaactgac
     5461 tgacaaagaa atccgctaac cgatgggaaa attaaaatgg gatcatatcc aacagcttct
     5521 ttccctccct tctgtcaaaa aacaatggat agctatttat ggacaactac ctcaggaaaa
     5581 agaggtggag gaattgtatc aacaatttga acattatctg tttaaagatt tggtcaagca
     5641 ttctaccttg aaacccgaca cattggaaac gatcgaacgg ttgagaaacg ctgggatcaa
     5701 tattggttcc acgaatggat ttaatgctcc tatgatgaca atcgtagcag aaaccgcaaa
     5761 aaaagaaagg tattcaccag acttcatggc aacttttgaa gacgtcgaag ggtatggtcg
     5821 accgtttcct tatatgatcc ataaaaacat gcagtacttc aaaaacaagt cggttgatga
     5881 agtaatcaaa gtcggagata cggtctcaga tatccaggaa gggaaaaatg ccggagtgtt
     5941 gacagtaggt gtaattgaag gtagttcgct aatggggatt tcttatgatg agtaccaaaa
     6001 attagagatg gggaaaaaga tcgtttaaaa cagtctgttg ctcttagatt ccaacaagcc
     6061 ggcgctgata tttgtgtaaa caatttaaaa gagttaacag aatacatttt gtacgctgac
     6121 atgaatccag aatgactttt atacaaaata agaggttgtg aaaaagctgt cctgtatcaa
     6181 gtaataaaaa cagccaagca aaaatagctc ctcatatttt tcgtttggtt aggcttatta
     6241 ccgcagatgc aagcttttga acaccgttta ttcgaaaaaa aaaagggagc tgtgacacga
     6301 cttttgtcac agtcccctta tttgcaaaca aacagtgttt aagagacaac ctctccacta
     6361 aacggtgttc attcagctga ctctcggtat ttgctcaaaa aacgataaaa tttgaaaagc
     6421 tattttctct tttgtttctc taatactcgg atcagaacgc tgatttcaca ttctcttttt
     6481 cttacatctt atctggtgca tgaagtccta gcaaacgaag gtcttctttc aataatacag
     6541 tcactgcata aactagagct aagcgtgctt ctttttgttc atcatcagct aaaatcttcg
     6601 tatgagcata gtatttgttg aatgcttgtg ctaatttgat tgcatgtttc gcaatcactg
     6661 acggttcgta tttttcccca gcagacaaga ccgtttcagg gtatttttga actaatttaa
     6721 ccacttccca gctggtatcg tcattcaatg catagtctgc tgtttctgaa gggacaaatc
     6781 ctgctttttc caacaggctg actgcacgag catgtgtata ttgcacataa ggtccagttt
     6841 ctccttcaaa tcgaacaact tcttccaggt taaagtcaaa tgtattcagt cgatcgtttt
     6901 tcaaatcgtg gaaaatgact gccccaaccc caacttgttt agctacagca tctttgtttt
     6961 ccaaatcagg gtttttctcg ctgatttgtt ctttagcaga ttggattgct tcatttaata
     7021 cttcttctaa taagacgatc tttcctttac gagttgataa ttttttacca ccttgcgtga
     7081 tcaaaccaaa tggaatatgg tgcatgtcgt cagaccagtc aaagcccatt tccttcaaga
     7141 cagctttcaa ctgtttaaaa tgatagcttt gttcattccc tactacatat agagattgtt
     7201 tgaagtcgta agtacgttta cggtacaatg cagcagctaa gtcacgtgta atgtatagtg
     7261 tcgcaccgtc tgacttctta atcaacgctg gattcaggtc ataagcagat aggtcaacga
     7321 tctctgcacc tttatcctcg ttcagcaaat gtttttcttc taaaagtttg acgatttcat
     7381 ccatcttgtc attgtagaaa gcttcaccgt tcaacgaatc gaaacgtact tccagcagat
     7441 catagatttt attgaattct ttcatcgatt catcacggaa ccattgccat aattgaatag
     7501 cctctttatc gccttcttcc agacgtttga accaagcacg agcttcttca tttaattctg
     7561 gttctgtttc agctacttca tggaattgga cgtataaacg aagcaattca ttgattggtt
     7621 ctgctttaac agcttcttct gtaccccatt ttttgtaagc gacgatcagt tttccaaact
     7681 gtgttcccca gtcacctaaa tggttgatgc ggattggctg ataaccgatt ttttccataa
     7741 tgaaaccgat cgaattaccg ataactgtcg aacgcaaatg tcccattgag attggtttgg
     7801 caatattagg agaagacatg tcgattggta ctgttccttg attcccgatg ttgctatccc
     7861 cataatgttc tttttctttc actactgttt gcaaaacttt tttgctgata agttctttat
     7921 tcatgaaaaa gttcaagtaa ggtccgacaa cttcgatttt ttcaaagttg gcagaatcga
     7981 ttttttctgc taaatctgca gcgatttgct gtggcgcttt tcggtaaact tttgctaatg
     8041 aaaaggctgg aaatgcaaca tctccgtgtt cagctgattt tggattttct agtaattgct
     8101 cgacttgttc cagtgttaaa tcatctttga cagcgtcata gacagctttt gcgacaagat
     8161 ctttattatt catctttatt cctcctaaag tgttcccttg attgttaaac aaaaaaaatc
     8221 tctagcgacg gcatacttag tatgccatca ctagagacga gatttcccgc ggtaccactc
     8281 caattgtcct aaaaaaggac cagctccatc tgatatcggt agacgaccgt ctgtttaaaa
     8341 cagaattctc caagtgcgct tcgttgtatc ttcttcattc ggcttccacc acttccgaat
     8401 tcgctagcca agaatgatac aagtactctc ttgttcaaca aatcttagtc ttattaaact
     8461 ttcttgaatt atatcagaaa aaaaaacgaa aggctagtcg tttcataaaa aaacaatcca
     8521 gatggcctaa aggagaagaa ataccacctg gatagctata aatcatttcg taaatacgaa
     8581 agacttaaca aattaatcag ctacgataat cgttccttct tcagaagcta aaagattctc
     8641 gatattttct aaagaagtga tgattgcctt agcgtttggt tttgcttcaa caaatgcaat
     8701 agctgcttct actttcggaa gcatgcttcc tggagcgaat tgcttttcat caatgtattg
     8761 tttcatttct gaaacagtaa cagtttctaa tttcttttga tctggttttt ggtaattgac
     8821 atacacattg tctactcctg tcaatacgat cagcaaatcc gcatcgatga tttcggctaa
     8881 tttttctgaa gcaaaatctt tatcgattac ggcttctcgt ccttctaatc cagtagctgt
     8941 ttctacaaca ggaatcccac cgccaccaac agagactgtg ataactcctt gatcgaccag
     9001 cgtttcgatg acacgtgctt ctttaatcga gatgggttta ggggaagcga ctacttttct
     9061 ccatccacgt ccagcatctt ctttgaatgt cacagtggag tcagcattca tttgttcttt
     9121 ggcttcttct tccgtgtaga atggaccgac tggtttactt ggatttttga atgaaggatc
     9181 attttcatcc acaataactt gagtgactaa agaaaccaca tctttatcga tccctttttc
     9241 cttcagtact tcgcccatgg cgttttgtaa ccagtaaccg atagatcctt ctgtcattgc
     9301 aacacatgta tctaaaggca ttgccggtgt tttctcagaa tcagcagctt gctgctgaat
     9361 caataggtta ccgacttgcg gaccatttcc gtgggagatg atcaattcat ctccttgttc
     9421 gataaatttc actaaatact ttgctgtttc cattaacgct tcttgttggg cttttgcact
     9481 tgcatccgta gacaagatgg cattgccccc taaagcgaca actacttttc gtttggccat
     9541 ttcattcgtc ctttcttcag ttctaccgaa ttttctagat aacaaaacga gccagcgttt
     9601 tgtgattttc cctcaatgct gactcgtttt ttcgtgagat gaatgtggtt atgcttaaac
     9661 gcgagggata aacaagttac ctaatgttgc tgccatgatc gctttgattg agtgcatacg
     9721 attttctgct tggtcaaatt gacgagcata tttgctgcgg aagacttcat ctgttacttc
     9781 catttcagtg atgccaaagc gttctttcat ttgttcaccg taaacagtgt ttgtatcatg
     9841 gaaagctggc aagcagtgca agaagatcaa acgatctgtg ttgtgtgttt tttctaccat
     9901 ttccatattg atttggtaag gtttcaacaa tttgatacgt tcttcgaatt tatcttcttc
     9961 acccattgat acccatacat cagaataaag gacgtctgct ccgtctacac ctttatcaac
    10021 atcgtcggta atcatcaatt gtgcaccgga tttttcagca aagccttctg ccattttgac
    10081 gatttcttct tcaggttgta attcttttgg tgcaacgata cgcatattcg ctcctaaaat
    10141 tgcacctgtg actaataaag agttagccat attgtttcga ccatctccgc agtaagcaac
    10201 agtgatacct tctactgttc caaagttttc ttggatagtt aaaaagtcag cgatcatttg
    10261 tgttggatgc cattcatcag tcaagccatt ccaaactgga acaccagaga attctgctag
    10321 ttcctctacc attttttgac tgaatccacg gaattcgatt ccgtcaaaca tacgtcctag
    10381 tactttagct gtatcttctg tggattcttt tttacctaat tggatatcat ttgcacctag
    10441 atattcagga tgtgcaccta gatcgatcgc tgcagtagta aatgcagaac gagtacgtgt
    10501 agatgttttt tcaaataaaa gcgcaatatt ttttccttct agatagtgat gtgggatacc
    10561 acgttttttc aagtctttca agtgttctga aaaatcgatc aaatattgta attcttcttt
    10621 tgtaaagtct ttttctgcta ataagcttct tccttggaat actgattctt tcatattaaa
    10681 cattctcctt tagattgttt ttatttaaga ttaaagagga aatcccgacg gcagctgaca
    10741 gtaagactgc cgtcaggaaa caaattactt caagtcttca cggacaagtg gttggctcat
    10801 gcagcgtgga ccaccacgac ctcgtgacaa ttcacttgaa ttgatttcta acactttgat
    10861 gccatagcta cgaagcaatt cgttcgatac ataatttcgg ttataagtga ctacaacacc
    10921 tggagcgatt gccaatgtgt ttgatccatc attccattgt tctcgaggtg caacgatctc
    10981 atctccatta ccagttggga tcagtacaag atcatctaat ccaagagcag ctttcatcgt
    11041 ttcgtgtaag ttatctgaat gagtaatctt gatatcatca ccatctggtt cgattgtaaa
    11101 gacatccatc ttaccgtctt tactttgaat tgctggatgg atagtgaatt tatcgtgatc
    11161 taccattgta aatacggtat ccaaatgcat cattgcacgg ttgttcggaa ttttgattgc
    11221 caacactttt tcaaatcctg aattttttgc gaataggtgg cgtgctaatt tttctaaagc
    11281 tttcgcatta gttcgttgag aaatcccaac agctactact ttatcgctta agatcaattc
    11341 gtctccgcct tcgatatgat ctggattttc acgatccaac catacttcga ttcctttatt
    11401 tgcaaatctt ggatgatgtt tcaaaatata ttctgtaaac atcgattcac gacgacgtgc
    11461 ttcaaaagtc atcttattga ctgtcatccc atttcccatt gatgcggaag ggtcgcgtgt
    11521 aaagtacaag tttggcattg ggtccatgta aaatggatag tcatcgtctg ctgacagatc
    11581 atatagactg ctagaacgta cttcgatatc ttttgtacga accccagcca tgattttatc
    11641 taccatttct tgcgtttcca ttgatagaag gaactcatga agaccctctc ttacagcatt
    11701 cgatgcaata tgagattcat ccaacatttt attcaagaat tgttctttga cattgcctgc
    11761 gtcaatcgct tctgccgcta atttttccaa gtaaagagtc tcgacgcctt cattttgcaa
    11821 tgtcttcgca aagttgtcat gttcttcttg agcaatcgga agatatggaa tatcatcgaa
    11881 caacagacga tccataatat ctggtgtcaa attttccact tcttgtccag gccgtttcag
    11941 taaaactgtc tttaatttcc ctatttcaga gaaaacgtga ataggtttat ccatgttgtg
    12001 ttgcctcctt ctttttgatt acatgtatag gatatcctcc ttttgtaatc actttcataa
    12061 ttttgtctca ttcaaaacga gacattcctc a
//
LOCUS       DAXLPC010000080        12017 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.080, whole genome shotgun sequence.
ACCESSION   DAXLPC010000080 DAXLPC010000000
VERSION     DAXLPC010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.080"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..258
                     /locus_tag="ACF3UE_002145"
     CDS             <1..258
                     /locus_tag="ACF3UE_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635525.1"
                     /translation="LKRKVTDRNKNLLNVVMICYISFLILGLPQAVFPEMFSGDWGIV
                     SYSILTLIAMVLGTSFYNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            465..653
                     /locus_tag="ACF3UE_002146"
                     /pseudo
     CDS             465..653
                     /locus_tag="ACF3UE_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1365..1970)
                     /locus_tag="ACF3UE_002147"
     CDS             complement(1365..1970)
                     /locus_tag="ACF3UE_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3635526.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2152..2487
                     /locus_tag="ACF3UE_002148"
                     /pseudo
     CDS             2152..2487
                     /locus_tag="ACF3UE_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387932.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            2652..2867
                     /locus_tag="ACF3UE_002149"
                     /pseudo
     CDS             2652..2867
                     /locus_tag="ACF3UE_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3005..3976
                     /locus_tag="ACF3UE_002150"
     CDS             3005..3976
                     /locus_tag="ACF3UE_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3635527.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4116..5429
                     /locus_tag="ACF3UE_002151"
     CDS             4116..5429
                     /locus_tag="ACF3UE_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HFD3635528.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5472..6338
                     /locus_tag="ACF3UE_002152"
     CDS             5472..6338
                     /locus_tag="ACF3UE_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3635529.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6335..7183
                     /locus_tag="ACF3UE_002153"
     CDS             6335..7183
                     /locus_tag="ACF3UE_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3635530.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7197..8669
                     /locus_tag="ACF3UE_002154"
     CDS             7197..8669
                     /locus_tag="ACF3UE_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFD3635531.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQKRIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            8686..9558
                     /gene="scrK"
                     /locus_tag="ACF3UE_002155"
     CDS             8686..9558
                     /gene="scrK"
                     /locus_tag="ACF3UE_002155"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFD3635532.1"
                     /translation="MIYGSIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKVAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(9793..11174)
                     /locus_tag="ACF3UE_002156"
                     /pseudo
     CDS             complement(9793..11174)
                     /locus_tag="ACF3UE_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            11636..11959
                     /locus_tag="ACF3UE_002157"
     CDS             11636..11959
                     /locus_tag="ACF3UE_002157"
                     /inference="COORDINATES: protein motif:HMM:NF015824.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HFD3635533.1"
                     /translation="MDSFQRLSLVNQFELLAKFEDQNRSYYERKIEILREGYEYHYDD
                     EIWSDLSEPFPKEDSRFVLDVLNMYRDINFSKSKLNLDENQITNSYYTHFGSVAKFSK
                     KSILV"
BASE COUNT         3734 a         2050 c         2419 g         3814 t
ORIGIN      
        1 ttaaaaagaa aagtgacaga taggaataaa aacttattaa atgtagttat gatctgttat
       61 atttcatttc taatactagg tcttccacaa gcagtgtttc ctgaaatgtt ttctggagac
      121 tggggtattg tcagctattc tatattaaca ttgattgcta tggttttagg tacttcattt
      181 tataatgctt ttgtaagtaa gcatgttgag gaatatgaag tattaatgta cttaaaagag
      241 aaaaaaacaa gtaattaata tgagaacacc acgcatagtt tttattttga gatattctag
      301 aatgaaacac attaagaacg aaagcaaagc aaaagacgcc agaacttcta ctaccttcta
      361 agttttttca tatttgtttg ttatgctata catagatctg cataattaga cttgcgctgc
      421 ccgttattga agtttcaggc agcgctcttt ttgggggatc gataatggaa gaagaaaaaa
      481 tatttgagaa acgctggcag ctagcatcaa gtgaacaaag agcaagatac aataatttga
      541 tcacctccta ccccactgtt gactagacat ataaggaaaa gaaatactta ctttggctgt
      601 gccagttaga tatagatacc tttgagatcc tagataaaat taaacagaat tgatcagaaa
      661 caagcgaagc cttctctcgg ttcgcttgtt ttgctattta ttagttggct cagggcaact
      721 ctaagctcgt ttgaaagaaa accgatggat aatccccttg tttgtaccac tttagaatac
      781 atggatgtac gtattgccat tgactcctat tagttactga aaaaaaattt aaacaagttg
      841 agtattgcag ataaatagct ccagtgaggt gaataactgc tccactcaag gcaatagata
      901 gctccatcca gggcaacaaa ctgctccact ttcatattta atagatgaat aaccttctgt
      961 ataatagaaa ggcatacctt tcggtatgac aacttataca gaatgttatt ttattggttc
     1021 actatcgaaa aattttggag ctttattttt ccggtatttc tcaacgaacg attagtttaa
     1081 ctgtgggaag ctccagacat acgattcgag aagttacttc tcgagcagac aggaaggggg
     1141 tgactgaact aaccgctgat atgagcgata cttggctgta ggaatatctt tttccggaaa
     1201 aacaaacaac agcacgaggt taccttcctg tagactggga atatgttcat aaagaactaa
     1261 tgaaaaagaa tatgacattg aaactccttc atagagaata tggggtacat ggaacataga
     1321 aacgaaaatg cacggtagaa aagcgaatga atatagtata aattctacaa atcattcgct
     1381 ttctttattt tatatatggt tggtcgagag agaccatttt ctttggcaat ttctgcaact
     1441 ggaactcctt gatttaacat gtccaccaca gttttaaaga ctaatcgttt ttgcggatct
     1501 gttgagttct cagaatattc aattggtcgc cccttatatc gaccagcttt tttggccaat
     1561 aatactcctt gccgctgacg ttcacggatt ttctcacgtt cgttttgtgc aatataactt
     1621 agcaatgata aaaacatatc gaacatagca gtatctagga gttcatttcc agtattaaaa
     1681 tctaaaaact gtgcatctag tatttttaat gctacttttt tctgtttcat aaaggtaact
     1741 gtatttttta tgtcttcata atctctgcct aggcgatcca gtgatgcaac aatgacacaa
     1801 tcaccttctc ggatataatt tagtaatttt tgaaactcag gtcgctggat atctttacca
     1861 ctggcttttt cttggaataa tttatcaatg ttaaggtctt ccatcattgc caattgtcga
     1921 tctaaatttt gatcttgtga agacactcta atatatccaa tttttgccat aaaaactcct
     1981 tttaaaaaat gatataattt acatgtaaaa tttacttgta gttttactgt tatcatagca
     2041 tttttaaaaa taaattttaa gtctacttat aatttacttt ggaggttttg aatgaatgaa
     2101 attaagcgca ataaaaattc ttttggtgtt tatttaggag agcctagctc ggaacagtta
     2161 aataaaggtg aagctcgtca tgctctatgt cgaaatatat tttatggtag aaaaggcaaa
     2221 ctttatcaaa cttattacga cggtatggag gaacagctca acgcattagg attagtaact
     2281 aatgctatca tatattggaa ttcactatat ttagaaaaag tctttgaaca aattaaaacg
     2341 gaagggttcg actgttccga agaagtgtta cgcaagcaat ttccattaat tagtgatcac
     2401 attaattttg ttggcaaata tagtttccgc tatgaaaaag aattatcgaa tggaatacta
     2461 cgtccgttaa atatagagaa ttattgagaa tgttcgtctt ttggttccta ccgtgcattt
     2521 tcgcacggat gttccagata ctatttttga atgtataaaa ttgaaaacac aagaatacta
     2581 ataaatcaac gattcttgtg tttttaattt ttcactaccg tgcattttcg tttctatgtt
     2641 ccatgtaccc caatcttgaa aaattaatta aagacttaga taaagccatt gacgacttag
     2701 tcgtggtgct accggagtat caatgtttaa ccagtatccc aggtattggt cctgtttagg
     2761 ctgctggaat actcgctgaa attggtccaa ttgaacgttt ttctgatgaa ataaaattga
     2821 caaagtatgc cggcctatat tggcgacaga gtcaatccgg taaatctgaa tacgaaaatt
     2881 tttttacgaa aagcttcacg tctaatatct attttaaaat aaaaatattc ctgctaattt
     2941 ggaatcgttt ccttcttttg gtataataat acctgaaatt cttttgagag gagttgttcg
     3001 tgaagtgaaa actactatga aggatgttgc tgcgttagca ggagttggtg tgggtacggt
     3061 atctagagta ataaatggag taaaggtgaa agaggttacc aaagaaaaag taatggctgc
     3121 aattagtgag cttaattatg agcctgatga atatgccaga ggtatgaaaa cgaatagtag
     3181 caatacaata gctcttattt tacctacgat ttggcatccc ttcttttccg agtttgccta
     3241 ctatgtagag gaagctctca gccaaaaaaa ttataagctt tttttgtgta atgcgaacgg
     3301 cagtgcggaa aaagaaaaag aatatatcca aatggtcaag cagagtaaag tagacggaat
     3361 tataggtatt acctattcag acattgataa atatgtatca tcaaatttac catttgtcag
     3421 tatagaccgc catttttcgg aacaggtttc ttatgtaacg gcagataatt atttaggtgg
     3481 gcaaattgcc gctcaagaac tacttactcg taactgtaaa aacttgtgct atgttggggg
     3541 tgtttcacct taccctaacg aaacaaacaa tcgtaaagct ggtttttaca atatttgtga
     3601 ggaaaataaa atagctgtga aggtattgga tatgcctgaa ccaattagca atttagagga
     3661 acaattgctc gctttttttt cggataatcc tgaaattgat agcattttta ccatcaatga
     3721 tttcatggct ttggatgtga taaaagccca aaaaaaacta gggaaggaag cacctaagga
     3781 ttttcaaatt attggttttg atggagtcaa gctatcgttg caaaaagact atttactatc
     3841 aacgattgta cagccgatag aggaaatggc caaggtttca gtagaaacac tcatggcgat
     3901 gattttaaat gaagaaccgc ctaagcgtgt ggtagtaccg gttttctttc acgctggaga
     3961 gacgactaaa gagtaaaaaa ccggtttata acgatttttt tgagataggt tgacagaaag
     4021 tgatttcaat gatatcttaa aaccaattaa ttggaaacgt taccaattaa ttgaaaaata
     4081 aaacggaaac gtttcaaaaa ataggaggaa catcgatgaa aaagagaatg ttagcaattg
     4141 cagcaatttt agcattaaca gctggaggac ttgcaggatg tggcagtaag gagaaaagtt
     4201 caggtagcag tgatccagga gaaattaaga tttgggttca gttttctgat gaaacgcctg
     4261 aaggaaaagc ttgggcagag attgtgaaca attttaatga tgaatacgag ggtgaatata
     4321 aagctgttac tgagtatatt cctcgtagcg gaagcggcgg tggatatgag gataaagtaa
     4381 atgctgcaat tacaaccaat acccttcctg atgttattac gttagatgga ccgaatactg
     4441 cagcttatgc tcattcagga gtcattgctc cattagatga ttatttgaaa gatgcggaca
     4501 tggatgatgt attagacagc attattcagc aaggaaccta cgatggcaaa atgtatgcgt
     4561 ttggtttctc agagtccagt gtgggtgtct attacaataa gtcgctgttc aaagatgctg
     4621 gaattacaga agatcaattg ccgacgttag aagatccttg gacttggacg gaatttcaag
     4681 caatttgcca aaagctgact gataaataca aaacgcctgc aattgatatg caaatggcgt
     4741 cgggagacga aatgctgacc tacgcatata caccatttat atggtcgaat ggcggcgatg
     4801 tcgttaatgc tgatggaacc aaagccgaag actattttaa cggtaaaaaa tccgttgaag
     4861 cgttggaatt tattcaagaa ttggttgaaa aaggttacac cacaatcagt cctattgaaa
     4921 aaggatttga aactggcaaa tatgccatga tgctgagcgg ttcttggaca atggcagatt
     4981 tagaggaaaa ctatcaagag attgattatg gtattttgcc ttaccccgtt tcagatgcaa
     5041 ctggggagtt agtttcacca accggaagct ggcagttagc aatgactgag aaaacagaga
     5101 aaaaggatgc ttctgcggcc tttattaagt ttgcaaccag tacagaatct agtcgtatta
     5161 tgagtttagg gaacagtgtt ctacctatca gaaattcaac agttgattta attaaagatg
     5221 aagtgtcgga aggaatgcag gtattaatta agcaaaacca actttctgga catgcccgcc
     5281 cagtggttgt agcttatccg caagtatcta gagcattcca acaagcagtt caagatatta
     5341 gctacttcga ggaaaaccca gatgtacaaa aagtagcaga tagtcgcgct gctgaaatgc
     5401 aacaggcaat tgatacttca ctaaaataga agtttctaaa gggggccaat caagtgttaa
     5461 aaaaaccgac aatgaaagac aatttgatag gttacggctt tctagcgcca gctttgctgc
     5521 tgctgacgat ttttctgatc atacccgtaa tcatggtaat ttattatgcc tttactgatt
     5581 attatttgtt aacgccagat gctagacaat ttatcggctt agaaaatttt aagcgactgt
     5641 tcgctgatcc aatttttgta aaaagtattt ggaacacggc taaatttgtt gtttggatta
     5701 ttccggtcca aataggggca gctttaggaa tggcacttat tatcaacaaa aatcgtaaag
     5761 gaaatatctt ttttaaagta gccttttttg cgccagtcgt gatgtcctta gtcgttattt
     5821 cgattttatg gttgtacttg ttaaatccta atgaaggtct ggttaatacg ctatttgcaa
     5881 agattggaat tgcttcgcag ccttttttga ctagtcccaa acaagcaatg tatacgcttg
     5941 ttttcgtatc ggcatggcaa ggtgcaggat atcagatgct gctgttttta gggggaatgc
     6001 aaaatattcc gcaagacgtt tatgaggcag ccgaaattga tggtttttct aagtttcagc
     6061 aatttcgcta tatcaccatg ccattattaa agcccacggc gatttttatt ttacttacca
     6121 cattgatttc ggcctttaaa ctaatcattc agccaatggt aatgactcaa ggtggaccaa
     6181 tgaattctac tatgacaatg gtttattaca tttaccaaac tggatttaca gaccgtatgg
     6241 taggctactc cagctccatt gcgttaatct ttaccactat gattggttta attacaattg
     6301 ctcaaagaaa attggtaaag gaggatgatc cagcatgacc aagaaatttg gaccgctaat
     6361 gatcgtagaa tattgtttgc tgttcctttt agcggcatta ttcattttcc cgatgctgtg
     6421 gatggtagtt tcctctatga agcctgaagc agatgtctat caaaatttag cttccttcaa
     6481 agctttttta cctagtttga atccagctaa ttggtttaaa acttatcaag aggttatttc
     6541 ccggttcagt gtgggaactt atttattaaa cagtattttt tatggtttaa cctttgcctg
     6601 tgggtcaatc attgtaaact ctttggcggg ttttgccttt gcgaaggtta atttttcagg
     6661 caagaaaatt atctttggag ctttgttagc tctgctgatt gtcccgatgg agacggtttt
     6721 aattccgcaa tttaccatcg ttaattcact aggcttagtg aatactcgct tggcagtgat
     6781 tttaccagcg atggccagcg cgtttaatat ctatctgttt agaaatttct ttatcgcgat
     6841 tccagaagaa atcattgaat cagcgaaatt agatggtgca aatattgtta aaattttctt
     6901 tcacatcatg ctgccaatgt ctaaaccagc catagccaca gtaggtgtct tatcctttat
     6961 ctccagctgg aatgattata tttggccgtt aatggtctta actgacagca gcaaattttc
     7021 aatgcaagtg gcaattacta cgatcaatac tacacagcca gtttatatca atcaagtgat
     7081 ggctgtttta accattgcaa cgattccact gattattgtt tatatcgttg cacaaaaata
     7141 tattctgcag ggacttggcg gttctggaac gggtataaaa taggagtgaa tagtgaatgt
     7201 tgcaaaaact tttaaaggcc aatgagttta ttgagaaaaa tgctcaaaca gtcaatcaag
     7261 aataccggaa taaatttcat ttgatggctc cgattggctg gatgaatgat ccaaatggtt
     7321 ttgtttatta tcaagaggag tatcacttgt tttatcaata ttatccttac gacagcatct
     7381 ggggaccaat gcattggggc catgctaaaa gcaaggatct aattcactgg gagcatttgc
     7441 cagtagcact ggcaccaggt gaaagctatg acaaggaagg ctgtttttcc ggcagtgcca
     7501 tagaaaagga tggcaagctg tatttgattt atacaggaca caatgttgtg gaagggcaag
     7561 ttcgacaagt tcagtgtttg gcagtttcag aagatggcat tcactttgaa aaatatgccg
     7621 gaaatccaat catcgcagaa gatcacttag cttctgttgc aacgaccgaa gatttccgcg
     7681 atcccaaagt gtttcagcga aaagaagact attttactgt agtcgctact aaaactgcag
     7741 atgctcgtgg acaaattgtg atgttccatt ccaaagattt actaacttgg gagttttatt
     7801 ccgtattgct ggagggaact ccagaacaag gcattgtatg ggaatgccca gacttgtttg
     7861 aactagatgg caaagaagtc ttgattcttt ctcctattca aatgactcca caaggcaatg
     7921 cttaccaaaa tacgaactca actgttgctt tcatcggtac tgtcgattgg caaacaggca
     7981 aatttctagt agagaatttt catgaaatcg atggcggttt agatttttat gcaccccaga
     8041 cctgtgaaaa cgaagcaggc caaagaataa tgattgcttg gatgcaaatg tggcagcgta
     8101 aaatacctac gaatgatctg ggccatggtt ggtcaggttc catgaccttg cctagagagc
     8161 tgagggtggc tgataatcaa ttgttgcaac ggccagtttc atcaatttat caagtaattg
     8221 atccgcagaa aaggattgaa tgggcgaaga ctgaagagaa tcgcttctta ctgaaggact
     8281 tagtatatga ccagcactat ttacgcttgg aaatcaattt aaaacaggca acgaaactag
     8341 aacttcacta tgcgaaggga cccgaccata cattactgct taactatgat gttgaacggg
     8401 agtgctttac tgcttccagg gaacacatgc cgtatgattt atcaggagct gaaaaggaag
     8461 tgttgaaaaa gcgcagtgtg acgattcctt tggaaaataa ttgtctaacc atcgaaattt
     8521 tccgtgatac ttcagctatt gagctttttc taaatgatcg tctgactatg agtacaactt
     8581 tttatgagac agaaaaagga caggattttc ttttgctggc agacagtgaa gtaacctttt
     8641 cattggaaag cggcttaatt aatctataga agggagagct cagtgatgat ttatggttca
     8701 atcgaagcag gcggcacaaa atttgtgtgt gccattggcg atgaagaaat gacgatcaag
     8761 gaaagagtga gctttccgac aacgacacct gaggaaacaa tacctttagt cattgacttc
     8821 ttcaaacaat accaagcaga tttagcaggg attgggattg gctcatttgg gcctatcgat
     8881 atccatcgcg attccgccac ttatgggtac attacctcga ccccgaaagt ggcatggcaa
     8941 aattttgatt tcatcggtac catgaaaaaa gaatttccga tcccgatttc ttggacaaca
     9001 gatgtcaatg cggctgccta tggtgagtat gtcttcggca gtggcaaagg attgagcagt
     9061 gtcgtttact atacgatcgg tacgggtgtt ggcggcggtg ccttacaaga agggcgcttt
     9121 atcgaagggt ttagtcatcc agaaatgggg catatgctcg tcgtccctca tccaaaagat
     9181 gactttgctg gcagctgtcc atttcatggc aactgtttag aagggatggc cgctggaccc
     9241 gccatcgaaa aacgcttagg gaaaaaagga caagaggttg cagaagatga tccttattgg
     9301 gaaatcgaag cctcctatat tgctcaatgt gcctacaata caaccttgat gttttctcca
     9361 gatgtgatca tttttggcgg tggtgtgatg aaacaacgcc atatgctgca aaacgtccac
     9421 gacgcatttg caaaattggt caatgggtat gtcgaaacac ctgagttaag caaatatatc
     9481 gtgaccccag cattagaaga caacgctgga acgctcggtt gtttggcatt ggctcgagaa
     9541 gcggtcttac attcataaac gaaaaaaggc tcttcgacat ttagtgttgg tagagaaaga
     9601 tacaactgaa aatttagtca taaccagtta ggcagagtgc ttaactggtt tttgttttac
     9661 ttggaagatc aagccttgaa tgagataaat tcttgctcga aagttatgga aatttcgata
     9721 gccgtaggcc acttgtattg tgcaatagtt ttttacaaaa aaaagggggt gcggatattt
     9781 ttttggacct ttttaacaaa tatatctttg cttcttccga tattgaagag ggcttagccc
     9841 tcctaaagat aacttaattc gttgattatt ataccaatga atataatcat ccaatttgtt
     9901 tataaactga ttgattgttg tattcttcca gtcacgttga taaaacatct cgttttttaa
     9961 tcgtccaaag aaaccttcgc acgctgaatt atctggtgaa taaccctttt tagacataga
    10021 gtgaagcaag ttggctttgt tccaatagtc caactaacaa tagcaccatc gtaacaatcg
    10081 acaagtggtg ataagtagat tttccctgcg ggaattctaa attcagtaat atctgttaac
    10141 catttttcat ttggcttctt tgctttaaaa ttccgattta ataaattggg gtgtgcagga
    10201 gaaatttccc cagcatacga agaatacttt tttcgtctag aaaatttaac aaatagattt
    10261 tcctcagtca tcaatctacg tacaactttt tcagaaagct ttttacccat attttttaaa
    10321 gcttggtgaa ttctacggta accatacgca cagaagttat gattgaaaat cgtgataatt
    10381 aattgacgtt ctttgtaata cttatctggt ttctcaagtg cttgtttttg ataaaaatag
    10441 ctgcttttag gcaactggag ctgttgaaga agctctttca aggtgaactg atttcgtaag
    10501 gcatcaatca atatcgtttt ttcttgattt gatagacaaa gaagattgac gcctttttct
    10561 ttttttagca gttcagccgc tccttcgagt aatgtttttt cgagctgtaa ttggtgtact
    10621 tgtttttgta agtcttctac ttcctttaaa agtagctctt tttgtttttc ctgatttttt
    10681 aaagtcatac gcaatggaaa atcctttcca agaaccgtgt ttttccattg atatagagta
    10741 actctactaa ttccttcaga ttctgctaaa tttttcctat tagtttgcgg tttatagaat
    10801 tttttcaaca cagcttcttt ttgatcttgt gttaacttta ccgcactttt tcggagtttt
    10861 ctagctcctg gtgcaagttc ttcacaccgc tgccgcaagg actctctatt aggataacca
    10921 agcatgcgaa tggttcgtgc ataacattga ccatattcaa aataatgatt caccgctatt
    10981 cgtttttgtt cttcagaata ctttgatttt tttcggtgct cctgatggag ctctccggat
    11041 tccaaatact ctttatacca tttccgtagt gcaccaatcg acggataccc taattctcga
    11101 atggttgcag cataagagca atcgtatttt aaaaataact gaattgccct tacacgctct
    11161 ttgtgggaaa acacacggac attcctccta agtttatttt ttcgtccagg attatgtccg
    11221 cacccccttg ctttctgatg acttattctg gttctttgag tgtcaatgca tagatgtgat
    11281 gtagctagtt agaaaaaaat tttgaatact ctttttttct ttcagactcc tttttaagta
    11341 agattttgaa gtgtgagtta cggggtcaga aacttaaaag tttttgatcc tttattttca
    11401 agtctgattt ggcagctttt cggcagctca tttatttatg gtcagaaata gatgctgaaa
    11461 ttttaatcta ttagcaaata gtccagaacg tatgaagagg agtcggatat catttgtcat
    11521 taacaccata aatatttata aaattcgtgt tcacctacaa ttaaatttaa tatataatat
    11581 tcgttgtaag ggcttataat tttttgttaa tgaacaagat aggaagaaac atttaatgga
    11641 cagttttcag agattgtcac tagtaaatca atttgagtta ttggctaaat ttgaggacca
    11701 aaacagatct tattatgaaa gaaaaatcga aatattgaga gaaggttacg agtatcatta
    11761 tgatgatgaa atttggagtg atctttctga gccatttccg aaagaagatt ctcgatttgt
    11821 attagatgta ttgaacatgt atcgagatat caattttagt aaatcaaagc taaacttaga
    11881 tgaaaaccaa attactaatt catactatac tcatttcggt tctgttgcaa agttttccaa
    11941 aaaatctatt ttagtgtaaa attgagaaaa aagacagaga gggcagagta atgaatcatt
    12001 ttaaaggcaa acaattc
//
LOCUS       DAXLPC010000081        11677 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.082, whole genome shotgun sequence.
ACCESSION   DAXLPC010000081 DAXLPC010000000
VERSION     DAXLPC010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.082"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            342..548
                     /locus_tag="ACF3UE_002158"
     CDS             342..548
                     /locus_tag="ACF3UE_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HFD3635534.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(750..1751)
                     /locus_tag="ACF3UE_002159"
     CDS             complement(750..1751)
                     /locus_tag="ACF3UE_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3635535.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(1756..3668)
                     /locus_tag="ACF3UE_002160"
                     /pseudo
     CDS             complement(1756..3668)
                     /locus_tag="ACF3UE_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
     gene            complement(3836..4342)
                     /locus_tag="ACF3UE_002161"
     CDS             complement(3836..4342)
                     /locus_tag="ACF3UE_002161"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFD3635536.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4502..4942
                     /locus_tag="ACF3UE_002162"
     CDS             4502..4942
                     /locus_tag="ACF3UE_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFD3635537.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(4968..6083)
                     /locus_tag="ACF3UE_002163"
     CDS             complement(4968..6083)
                     /locus_tag="ACF3UE_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635538.1"
                     /translation="MKNYHLSCSLKKGNPIEGEEYRIRYFFHLMYWQSFDENHSDILS
                     SIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSITYVPEEMNKFVHPL
                     ITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYLEEDLLDTPDKVQES
                     WGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGTKKKVDAFGKSAEDR
                     DFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCMLVRDIFIKHEQPVIF
                     YIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYPIDKKAYDQTNTQIF
                     YWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6128..6484)
                     /locus_tag="ACF3UE_002164"
     CDS             complement(6128..6484)
                     /locus_tag="ACF3UE_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635539.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(6782..7756)
                     /gene="sgrA"
                     /locus_tag="ACF3UE_002165"
     CDS             complement(6782..7756)
                     /gene="sgrA"
                     /locus_tag="ACF3UE_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HFD3635540.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(7952..8791)
                     /locus_tag="ACF3UE_002166"
     CDS             complement(7952..8791)
                     /locus_tag="ACF3UE_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFD3635541.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            8976..9863
                     /locus_tag="ACF3UE_002167"
     CDS             8976..9863
                     /locus_tag="ACF3UE_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFD3635542.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(10457..11152)
                     /locus_tag="ACF3UE_002168"
     CDS             complement(10457..11152)
                     /locus_tag="ACF3UE_002168"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HFD3635543.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(11136..11534)
                     /locus_tag="ACF3UE_002169"
     CDS             complement(11136..11534)
                     /locus_tag="ACF3UE_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFD3635544.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         3479 a         2318 c         1750 g         4130 t
ORIGIN      
        1 gcttttggcc tcattttagg ttatcatttg taattttatt tcacagttga tatgattgtt
       61 atgtaaaata aaaaagttta ggatacatcg aatttttggg gaaattcttt tgggggtatc
      121 ctaaatcttt tctattatat tcccatattt tctattattg gtctagacgt atgatggtaa
      181 actttgtacc tatctgattg ctgaatcatt aattgcttat cattagccat ctttgtttca
      241 agttcgctag atgatcattt tattcacatc ctaacaaact tgtcacattt atagattctt
      301 aatctattta tcatacaatt ataaaaaagg aggtgctgct tatgaaagct atccatattt
      361 ctttgctttt tttcgctagt gcattgattt tatttgctat tcatctttgt tcccagcctt
      421 atatcaataa caacggaata ttagtggaac cagcattctt ttgcttacca ctcggctttt
      481 tgtcccttct tgcctccgca ggcttcggat ttgttgcttt ttttaaacga tcaaaacaac
      541 aaatctgact tataaaattt acgtaaaaga gatcgtgaca ataatcgtgt gatattccca
      601 aatttcgaat aaaaggtgcc ccttgccatc tctaactcct cagtcacaag ttacaatatt
      661 cataaaccat gaaaagcttg tttattgaaa ttgctccttg tgacttggag ctaagtgaca
      721 gattacaacc tcttttgcat cataagactt tactccttga aaaacattac taacttttga
      781 tatgtttctt gcgcttgttt attgctgaaa tcaaactgat attcatggtt caaaacagca
      841 tttttctccg cataatctac ttttgtgact ttcacccccg ctttctcaaa tacagaagtt
      901 acttcttcca tttgtttcgt aaacgtattt gtatttccat ccgttaagaa tgtgttttgc
      961 gtccaacgat ccgcatgtct gaccaaggct aaacttttga ccttctctga ttgttcaaag
     1021 tccttattat caaagtaagc ccatccacat ttttcataaa gaaagctaga gattttatca
     1081 cttacttgag taagtgcaga aggatccaac agaccagaca aagaaataaa cttcgtaatc
     1141 tgcttgttct ccaaagtcgg atcaagatga tcagcttttt taatttcttc attttgaagt
     1201 gctaacaaat attctccact aatttgtgca cctgccgaat ttccaccaat cgaaatattc
     1261 gaccaatctg cttgatcttt tatctctttt ttagctgctt gaatggcttc gttcaattgg
     1321 ataactggtg taggatgttt tgcttccggt gatcgttcat aatctatatt tacgatgatt
     1381 tgctgcgtgt ctgaacatag atattccaaa taatcacgac aatcattttt atcccctcct
     1441 acatatgcgc ctccatgcat ccagaaaaga atcggtaatt ttttcttttc cactttcggt
     1501 gtgtagatat ccatattatt atttttgtac tttgaaggat aggatatttc tttttttata
     1561 tcgatttgtt cgattttttg ctggaaatca tctggtcggg catatacttg ttctttttca
     1621 cttgtgtcaa attgttttct aacaagcaag ctaatcggct ttggtgtgat ttgattaatc
     1681 aaaaatacag tgactaaaat aactacgatg ataactggta ctgcaatcac tattcgcttg
     1741 aaccatttca ttcatttacc ctctctttct tcgccaaatc catgtgataa tcgtgctaac
     1801 agataaaaat ccacctgaat aaatgagaag cgaatgtttc ttttctccag ttttcggcaa
     1861 cattcttttt ttgcatctgt ctttttttgt actttcactg tcatctgaat cggttgcgta
     1921 tcatcacttg attgatcctc tcgaggttca ttctttccct tattgtctgc attctctgtc
     1981 ggatcttgct tttttggtgg agctactggg atttttttgt aatagaaaat aatagttggt
     2041 atcgtctcat taaaaatccc ttcagtcggt ccttcaacat ttgctaattc gtatccttcg
     2101 aatgtctttt gctctgtcat ataattttct ccataagctc cgtaaagctg gatttcgtcc
     2161 tggtctttga gtagactttt attgttttca tccacatact ttacgtttat ctgatcatgg
     2221 aacactactt tcaaaaagtc cgttacatgt ttcgtgtagg cagcatggtc aacttcctgt
     2281 gcctttccat gccctgctcc ttctactaat aaaagatctt tataccctcc tgataactca
     2341 tataattttt gcgcgttaga cacaggtact acatcatctg ctgttccatg gataatcaat
     2401 ttaggcaatg aatctgacat tccaatcgta ggtagagcag cttttgtatc caaatgcatc
     2461 tcctgatcaa aatagtattg tttcaaaagg cccataaata aatcttcatg ctcttgatcc
     2521 ccaatgatgt ctaactgatt ttttatggca tccggtagtg cgggggctac tgtctggctg
     2581 tacgtaaaac gtagttgttc atcaattgat gcaaatccgc aattttcaat aattcctttg
     2641 acattgacag gaatatcttt cgctaataca gacatcatcg tagctgctcc catcgaacca
     2701 ccataaagta aaatcttttg agatggccgc tctcgaactt cttgatttat ccagtaaagg
     2761 acgtcatctg actcatattg tccataggtc acataatcgc ctccgctatt accagtcgct
     2821 ctggaatcaa caaataataa attatacccg gccttataaa aatcattgta ttcttctgta
     2881 acgatcccgt tattccaatt ccctcgaaat ccgccatgga tcatgactgt tttatctgaa
     2941 ccttgatcga cataatatgc atatacatcc atcattttgc catcttgttt gtttagtaca
     3001 gtttgatgaa gttgttttgt atttggatag aagcctgtgt tttctgtagg cgttgtccca
     3061 tcatctgtac ctccaagcat cgacatcaac acactgtttt ttgcaaaagc gatatcgtac
     3121 aatagataag tagcaatcag atgtttgata atctctttat ctacaccata atcattaaca
     3181 gcaagctcag tgactaataa ctctattaat tttgacttga tgtcttctgt tggtccatta
     3241 agtatttctg tcatctgttt accgaagtaa ttcaaatatt ctttaccatt gaaattttca
     3301 cctttaccga tatcatcatt ttctgtccca ttctctttgt cacttacttt agcagaagag
     3361 gattcgtcgt ttgacatttt tgtagctgtt gcttcttctg tttgttggtt atctgtggta
     3421 gcggtcgttt cttgatctgt gctagtaaca gatgtctcaa ccgttgtttc agtatttgtt
     3481 tctgtttgtg aagtactcga tttcgtttca tttccagcat cagtagtttc tgtggtttct
     3541 acctcccgag attccgattc ggaagaaatg ctctctccat atactgtcca ttgcgggacg
     3601 cttgtactta cagcaaataa gatgaccaac gctcccttta atacttgttt tgttctcaag
     3661 ctattcactc ctttttatgt ttctaggaga attatatgta aacgcaaaca ttttttatac
     3721 aaaaaataaa tggtttatcc cataaaaata gaacaggatt attttctcat tttacgtaat
     3781 aaagcagaat ggataaacca gtatccattc tgcttttttt aaacgaagaa acaacttatt
     3841 gctccaaaaa tgtcagaaat cgtttatccc aaattttctc gtaaaaagcg attgtttcct
     3901 ttgctttcat aaaaggatta tcataagttg tcgttgctcc tctacacatc ataagctggt
     3961 atcctaatcc atgagcaaac ttcacagtcg tatctataca atactctgct tgtgccccac
     4021 ataattcgat cgaatgacag tccaattcag ttaataaaac actcaaatta gtcttataaa
     4081 atgaattcgc atgggttttt ctcacaaaat aactgtgctc aggaatagat aattccgaca
     4141 atagctccca tggttttgtt tgtggcacta attgagcatc ttcgtgttga acgaaaataa
     4201 ctggtttccc aatcgtttcg tatgttttga ttcttttatt cactaatgct gtcactgttt
     4261 ctaattcgtg tatcggcgaa gaatcaaaac ataccccttt ttgtaaatcg atcactacta
     4321 ttgcgtcggc tgtgtttgac atacttgtgc cttctttctt ttttcttgat ttaatagtat
     4381 ttcttatcta gctagttcca ttatacgtga caacattttc ttattttaca cctctaaatg
     4441 gcacttttcg actatttctt catgttatta tttcataaat acttagctat tggaggaatg
     4501 tatgatgatt aaattgtata caggttctgg ctgctcgtct tcaagacgcg caaaacgttg
     4561 gcttatcgtc catgatatac cgtttatcga acagaactta attcgtcaac cactaaccaa
     4621 aaatgaattt atccacttac taaaattgac aaacaacggc gtgaccgaaa tgctctctac
     4681 tcattctatt agttataaaa atcttgttca cagaatagat gaactcagtt tgagtgaact
     4741 atatattgag attcgtacat ccccttcttt attgaaaaaa ccgattatct acgaccaatc
     4801 tgcaaaactt ttgactggat ttagcgaaga taaaatcagg atgttccttt ctaaaactaa
     4861 aagaaagcaa gagctcaacg aactcttgct ttctggtcat cttgtcgatt ttaaagaaaa
     4921 taatcttttt gcaatgtctt aattttggca taaacaatct gcttttctta attaacgaaa
     4981 tccaattttt ccaatatgga tctatttttc tcattcctga tttttatgat ttcagctttc
     5041 agacgcgccc aatcattttt tgtaggttgt ccattccagt aaaatatctg tgtattcgtt
     5101 tgatcatatg cctttttgtc gataggataa tcgctaatga caatatcagg taactgatca
     5161 gcggatgcac tatattttat tgggcgttca gtcatagata atatcctttt ctttgcccat
     5221 aattcctgtg ttttaccata ctttgattga atatagaata tgacaggttg ttcgtgtttt
     5281 ataaaaatat ccctgactaa catacagtat tgaaaaatca accgtctgtt cttttcataa
     5341 taagtattaa gctctggaat tctgcgagct accccactaa aaaactgttg catgattgga
     5401 tacatcactg gaaatatatg ctgaaaatct ctgtcttctg ctgattttcc aaaagcatcc
     5461 accttctttt ttgtcccaaa aacccttgaa tacaaatgga tcattgccaa attgacatat
     5521 agataatttt tttctgaagt tgtaaaacaa atcttgaagt ttttttcaaa attttctaca
     5581 atagacgatt caatccagcc ccaactttct tgtactttat ctggagtatc caacaaatct
     5641 tcttccaaat aggtgttcat tacaccaaac ataaaataaa ggtaagcttg ctctgttgga
     5701 gtgatgtgat tcatcgacca gaagtttgct tcaaaaaaag gctctagtat gtaatgcgta
     5761 aactcttctt ttgttatcaa tggatgcaca aatttgttca tctcttctgg gacatacgta
     5821 atcgagtggc cttgtttcat tcgttgcaac gaaattctta gtaggctgat ccatttcttt
     5881 ctatctatac tacgcgtata tggcgcatgt ttcgcaaatt tttctaatag ttgacgttta
     5941 ttttttatac ttgataatat atcagaatga ttttcgtcga atgactgcca atacatcaag
     6001 tgaaaaaagt atcggatacg gtattcttct ccttctatcg gattaccttt tttcaagctg
     6061 caagataaat gatagttttt caaaatagta ttaagttctc ttaattttct ttgaatcgta
     6121 cgcaaactta tataattttt tgactaagat tttctaagga ttgataagta cctttgtaaa
     6181 gtgaatccag taaaatataa ccaatcgttc cctctaaaag tatagaataa actttactca
     6241 gtaaaaactg agaagaaaac tcgactttta tcatcttgtt ttctgaaaga aaagataatt
     6301 tatattctgg atacctttcg caaaacgatt ctgcttgttg aatcaccgaa ttcatcttag
     6361 ccagggtgta gtttagatct aaagcgatat ccttcaccac atataatttc tcgtctcttt
     6421 cataacaata gttcaaaaat tgatatactt gcctttcatt gatatcaata aattcttcaa
     6481 acaaagtaca tactcctttt tatctattat ttagacttat tccgacagct acatgaataa
     6541 cgtacaaata gattcgttac tgatttttca gagatactac catgcgcagt gtgcattgtc
     6601 aattattctt gctcttattt tccatttgtg ttcctgttat ttcctgtttc tcaaatatgt
     6661 tagtaaacaa aaatagatct ggcaaagcta caacttcgcc aggcaataca gcactctcga
     6721 atgaaatatt cactcaaaaa tctatcgttt tattcaattt tagatctgtt gcttttattc
     6781 tttatttcac tcgatggaag agagaacgaa aatagcttgc tcctacaatc aaaatgagta
     6841 acacacccat ccatgtaatt agcttgttca aggttctact accagtttct ggtaaatcgc
     6901 tttttctatt atctgtttct ttcgcttttt cttgatgatc aattccacga gaaacaaaat
     6961 caggctgttt tagcacactt tttaggttgc tccctgcatt tctcttttgt tccttagttg
     7021 gtatgatagg taccaaatca agttcattat ttacttttcc tgtgctgctt tcgctgctcg
     7081 tgcttcctgt gctactctca ctactcatgc ttcctgtgct actttcacta ctcgtactct
     7141 ccgtactgct ttcgctgctc gtgcttcctg tgctactttc actactcgta ctctccgtac
     7201 tgctttcgct gctcgtgttt tctgtgctac tttcactgct cgtactctct gtactgcttt
     7261 caccgctcgt gttttctgta ctgctttcac tacttgtgct atccgtactg cttggcggtc
     7321 caacaactgt ccaactgctt ggtttcaaat tctccgtgat cgtcatctgt ccatcataaa
     7381 aaacaatcaa atcaacttta tctttactct tgatctcatc aatcgatagt tctgcagaaa
     7441 tcattattgt atactcaata ccagcggtcc attgtacgtc ttttaaataa acttccccaa
     7501 taactttttc tgaacttcca ttaccatccc aaccatatgt tagaacagca tgtacatcac
     7561 tagcattcac gcttttgttt ggtttgactg gaatagtaat gacttgttgt gtcatgtcat
     7621 aaacaatccg atcagttttc acagtaaatg aaagattctc atttgcccgt tcatttgcag
     7681 aagtactgat tccaatcatt gctgcaatta tactcagccc aagaataaca aataatacgg
     7741 tcgctgtttt cttcatttct atcactctcc atataattac cttctatttg ataaaggaat
     7801 tatataaaat gaaaatgatg agaacacgac agtcagttgt gaaaatctaa caaaagatgt
     7861 cgtgtattcg cttgaatttg tttacttttt cgtttaatca atgacagact taaaaaagca
     7921 agaccgatat cagccttgct ttcttcatct tttattgata aacagcagtg tatttcttca
     7981 tccgctttgt tttatatgca tagagtaaca aaccaacaat caagactaac aagaataatg
     8041 tagttgatat agatgcttca gccccaaagt ttcccccagt aattattgta ttttgcgatt
     8101 ggatcagagt ggagaaaaaa ccttgttctt gcgttccgct gactggtata cccaaaatag
     8161 ctccttgtgt ccaattccaa gtaatatgag caccaatagc cgtaaataaa cttcctgtac
     8221 tgtagataag tgcgctgaaa aagcaacctg ctaaaaagat attgaaaact gccagaaatg
     8281 tcatgttagg attcaatccg tgcaaaagag caaataatgc agcagatcca atcattgcta
     8341 ttaacggacc aaatctaagc atctgatgct gaaaaaagcc acggaataaa agctcttctg
     8401 atgcccccac tgcaataaat aaaataaaac tcgttatcag cggcacaatg tttgcgtttc
     8461 ctgaatctaa ccgatacgcc cccgtcaaat ataatggact agtaataagc agaaacactc
     8521 caattccaac aacgagacct cccgctaaat acccccagtc ttttcctcga acagaaacac
     8581 cataatcttc tattcttttt ccttcgacct tactagcaag aaataaagct agtaaaaaaa
     8641 cagctaaatg tccgaccgta ccggcaattg ctccaatcca ttcactattt ccaataaaca
     8701 tatccgcaag tgcattattg acaagaattc ctaaaacaaa accaactaag actattaaaa
     8761 cagatccaat caaccgaata atcctgatca tctttcatcc ctcctttata ttaagtttaa
     8821 caaccctttt ctttcttgtc tcgtgaaaac tatgtaaatg ttctccatca tagagagaat
     8881 agatttttac gaactaagaa tatctacagc aaccttacga aaatgaaaga ctgtctccct
     8941 aattcttctg ttagactgtt tttaataagg aaaggatggg aaattttttg aaaaaacaac
     9001 tactaattat gtgcctttca gcatgtgcaa ttttactatt ctcaggttgt agcaagtcca
     9061 atgaaacgat tgcaacgttt aaaggtggaa cacttacagt tcaggatttt tatgataacc
     9121 caaaagttaa atcaaataat caaacactat taaaaaaaat gattgtcttc aaagcatttg
     9181 atgatgtata cggaaaagag atttcttcaa aggaagtaac aaaagaatat aatgaacaaa
     9241 tcaaaaaact cggtccaaac tacaaggaac aattaaaagc agttggccaa acagaagaga
     9301 catataagaa actctttaaa cagatgctgg ctttccaata cggtttgaaa gccaatgtaa
     9361 aattaacaga taaagatcta gacactgctt ggaaagaatt ctatccagaa gttagtacac
     9421 agatcattct attttcgact aaagaagaag cagataaagc aaaaaaagaa gcaaatgaag
     9481 gagaaaattt ctccaagctt gttcaagctt atggaaaaaa taaaacatta aaggaaactg
     9541 atggaaaaat gaattttgat tcaaccaatc cagagattcc tactgaagta aaaaaagcag
     9601 catttaaact aaaaaacggg gaagtttctg atatcattcc tgtaacagat ccaacgactt
     9661 atcagcaaag ctattatcta gtaaaaatgg taaaaaaaca ggataaaggt tctaataaag
     9721 acaaatacaa atctgagcta gaaaaaattg ctaccgaagc aaaaactctt gatacggaat
     9781 tcatggataa aacaatccgt aaagtgatga aaaaagacaa tgtaactatt aaagatcctt
     9841 atgtaaaaaa tatattcaaa taaacaaatt tgacccaatt ggggatgtgg caaaatttga
     9901 gaagtgattt ttggaaattc cttcttattt ttgaggcaaa ccacttttgc cacaacttca
     9961 tcggggcctt tttttatttg taccaaaaca aatcactgga tttgttacaa tcatgaggat
    10021 ataatttaaa aaagtttttt atttctatca catgaatcaa tgcgccatta agtagattct
    10081 ttcatgcttc cctatttttt cacttgccgt atcgcttcaa aaacaactat cataaactca
    10141 aactcgactg aaaagttatt ttaaaaaaga ctaaaaatat cccttctgga cttgttcttc
    10201 ttattctgtt atactagaga aacacgaaag atatttttat gcgacacttt tcatttgttt
    10261 ttatgaaatt tattcaaaac tggcgtaact tcagagttac aaggatgtat tagaggttag
    10321 ggaatacatc gtttaaatga gaaataagta atagttagta atagtcaccc aaactttaaa
    10381 ttaatgaata ttgaatcgtc agatagcctc ctcgagtttt cgagaaggct atcgtttatt
    10441 ttatggagaa attgattcag aagtaatcag cgaccttttt tagttcacca atcgtttctg
    10501 cttggaaagt ttgcacccaa tcttcttgga agcccctcac tgctttatca atcgagggca
    10561 tctctaatac ttgatctagt agctctttac ctaacgttat cgcatgagct ccagatcgaa
    10621 tggctgtagt gacttgttca caatttttga aactagctgc taatattttt gttggtcttt
    10681 gcgtacgttc gatctcagtc cgcaacgaat caatcacttt catagcatca atgccttgat
    10741 tttgcatcct gttataataa ggtgcaatat aatctgctcc attattaata gctaaatacc
    10801 cttgtaattc tgtgtaaata gctgtaccgg taatcaaata accttctttt ttcaactttt
    10861 tgatcgcttg aaggcctgct tgattcaccg gcaccttgat aaacgtatct tttcccagtt
    10921 cttctatgat aactcgagca tcctctatca tttcttcttc cgttcttcct attgtctgaa
    10981 tatggatagg aatctgtccg attatttttt tgatttcttt catatgcgag aagaagtttg
    11041 acgctccttc ttttttcaga attgtaggat ttgttgttac gcctgttaaa ttcaaaaact
    11101 gttgacaaga ataaatactt tttgtatttg ctgtatcaag catgatttcc atatagcttt
    11161 cccccattct gatcctcttg atcgatttta atgattgtcc cctttcttaa atgcggcatt
    11221 tccttatctt ctacatacat tgttcctgga agttccggct catgagatcc atcaaatttt
    11281 atcgtgatat gtcctaattc attcaaatta gtttggacaa catctcctac tgctgtgatt
    11341 acatacattt gtttatcaaa acagagcttc atatcacaag ttatttcttt tcttacctga
    11401 ttcaattcaa tcttataaca ataatctgtt aatgtttccg gtgcttcatc tccaaataaa
    11461 atcattattt tttctttcct gaatacttct gcttctatac caacatctgt tacaaccgtt
    11521 tcaaagatcg tcatctctgt tcctcctcgt aaaatatcat ttgtctaata gtttttattc
    11581 aaaatgtttc tagattataa aatttattga ataacacatt cctaacggaa tttgtttcga
    11641 tattgtgtga tttctcagag tacaatggat gtatgga
//
LOCUS       DAXLPC010000082        11538 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.083, whole genome shotgun sequence.
ACCESSION   DAXLPC010000082 DAXLPC010000000
VERSION     DAXLPC010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.083"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            162..962
                     /locus_tag="ACF3UE_002170"
     CDS             162..962
                     /locus_tag="ACF3UE_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFD3635545.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKVSGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTQNLGMIKEK
                     DEEEMLWKVDGIEYVLDKAEHLVKNAKESLLIQVWHENLTDSLLKTLQQAEKRVDKFV
                     LILFSSSHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESSEELKAKYGEDFEGIRKIY"
     gene            978..1856
                     /locus_tag="ACF3UE_002171"
     CDS             978..1856
                     /locus_tag="ACF3UE_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFD3635546.1"
                     /translation="MIRNILLALIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFITFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGVKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAAFLIFMGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFDEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYVLKWIVILVLLYS
                     AYTMLGSQLKKVSAAN"
     gene            1869..2849
                     /locus_tag="ACF3UE_002172"
     CDS             1869..2849
                     /locus_tag="ACF3UE_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFD3635547.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENLKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFDRASRFAEEMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVNKAKENNLGKLIY"
     gene            3371..3589
                     /locus_tag="ACF3UE_002173"
     CDS             3371..3589
                     /locus_tag="ACF3UE_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635548.1"
                     /translation="MNFFQNVFTDFVGDFKYLIMLAMLGGAAYIAFERKASKAIPLIL
                     VLAVAVWLVGDTSGVFNWILDRMRSWGR"
     gene            3591..3998
                     /locus_tag="ACF3UE_002174"
     CDS             3591..3998
                     /locus_tag="ACF3UE_002174"
                     /inference="COORDINATES: protein motif:HMM:NF024062.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HFD3635549.1"
                     /translation="MSEIRNWTKIWYIERVFYKLWDGVALPRPVTQTFAIWFGIGFFG
                     GIFRIFPFVMEHTITRQFFCPWLFAFLMTRKQFQGRKPYNYLASFLLFQCRSKESFHG
                     QWVKPIEKKEIKRGIRCVVRYGGEKDATTKTSA"
     gene            3973..6510
                     /locus_tag="ACF3UE_002175"
     CDS             3973..6510
                     /locus_tag="ACF3UE_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3635550.1"
                     /translation="MRLPKLVPKIPFYYLEDNLVFGEEDRVYAYYEFPMYSYSFVGED
                     QAYQLQQAIMRLIRQSHSSHVRFFFCTNEEKIEKTIKSSKELVRSKGELKTIAYQHLE
                     GVQHILEELHGKYIQNVCWYVGIELVLEEIAPKEAHWLKEFRIAAKDFFHRSNARLFG
                     DFETIPNEKIQRYKRLENLLYNRISKYFRLRKTTPEDMVFLVEHLEGKKEQSLDEVMY
                     RPNSFKEETNTYTYHYDVLNLASAGITEKKNYLILEQGTEKEYITYLSLSRMTRDLVF
                     PFQSEIYYFLQSELDFPIDSWLDVNLLDNRLALAKVRGKKSDLSDIYESGMSVGKDVG
                     NNVREAYQSANELEQKLEDTREDLYVLSLNVRVSGKTYDEMLKRVSDVRNFFDVYSMY
                     LEVPCNVQLLLHFGSYPAGRRVIEDYRQYVGAEFIASLGIGATQQLGDGCGIPIGFNA
                     ETGIPVFIKPWLAAQGIKGTVTNTLAKALIGSLGGGKSLTENLLLFWSVLFGALAFCI
                     DPKSERSNWSEDLPYFAPYLKTVNITSEKENIGLLDPFQLMRRKKDQESLALDVLTYI
                     TGVSIRDEDRFPLLQRAVKTVSDFEGTKGLLLVIQELYAQEAATAQRLAKHIESFKEL
                     SIAGLLFGDGTNQQGLNLDAKCNLALVQDLTLPDSETVPEDYNSSEILSIAIMMSLAT
                     YALDFIKQNRKIYKAVGLDESWAWLNVAQGKILGDKLVREGRSRNAGIDFSTQNTDDL
                     GDEKMRSKIGLKFIFRSNDREEITKALSFCGISVTEENIQRVKNLENGECLFCDIHGN
                     IGILYVYYWFEDLFHAFDTRPPMEETYEEEEYKDEILEKLVEEIEVN"
     gene            6511..8532
                     /locus_tag="ACF3UE_002176"
     CDS             6511..8532
                     /locus_tag="ACF3UE_002176"
                     /inference="COORDINATES: protein motif:HMM:NF046089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFD3635551.1"
                     /translation="MKQWYSKVSFLITRRKLVFISLVIMMGVFFFHPSLVEAAGWIKE
                     TLGGKNAVYDFETYPLDNYNLDFFVDTSWNWLPWKWGEGISNTVIYGIFAVTNILWML
                     NVYLCYFLGFLVQEAFELDFLSELIGSLSHTIQNIAGMNRTGTLSHGLVPFFGGLLIT
                     LAGCSVVYQGIVKQHPTQAIQQAVTFLFTFICCGVFFMNTNTYLEKANGVQKEINSEM
                     LTIAKNLLPEQKEKPDAIKAIRENLFAIQIKQPWLVMQFGDSDIKTVGEERIINLLKE
                     SPYDEGEQRNKLVEEEVTKQKNGHLSVQKVYLRFGMVFLTLIVNIVISMSVLVLIVIL
                     IASQVLFLLFIGFLPVAMIFSLFPNSGSLLGNALQKVFQLLFTKMGILLILTITFSIS
                     HELNHLSKDKGMIWTSFLQVTLWLSVSTRVNELLGWMKIGGVQTRAGDRTGRFLRGMM
                     LGTMGQKMIRGIGENFVGGTAGGVAGQMISKSMSGQRSIASTPLIERVGKKVSAMTEL
                     PATIESRAEQWKRTIQYVPTNAQYKAQKMKYDYFSGRMNESERQTRARNLANERQKNF
                     YEARKDALQLEQQERKQRAMRSMAHQTGKTQVTSGKLQTRKSAMIGRTEQFPTIEKRS
                     NISNIAKNKKLSKQEHPIHERSTNRKIETPVRWTSTSRQNARKGRTKKE"
     gene            8679..9467
                     /locus_tag="ACF3UE_002177"
     CDS             8679..9467
                     /locus_tag="ACF3UE_002177"
                     /inference="COORDINATES: protein motif:HMM:NF024056.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFD3635552.1"
                     /translation="MVFSVCFGVYNNLTSQDTHTIHETKVIDKQLKDMTGIESYVKNF
                     AFLYFTVSLESDQQINRSKAVESYLADGLQMDNEIDKDIETNVKVKNVSIWAIEEHES
                     KKHTFVVMFHVLLEIEKEFKERVYKVEVYRNELSYAIVKLPIVASNVKKATIKVDTRF
                     ETTSISRKEQEELEKFLYTFFRIYPKANAEELKYYGTTLLPIQQPLAFEELSNLQVAK
                     KEGRYEIHCNILYQDQETHLWFTMYYEMSMKQLENGNFRIEAIH"
     gene            9539..10558
                     /locus_tag="ACF3UE_002178"
     CDS             9539..10558
                     /locus_tag="ACF3UE_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002386462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD3635553.1"
                     /translation="MSSGESKHMDSAVGVTHTGEYIETLPIFSEIKGRGPITDEHAQA
                     AVGAAVKYQLLPSVILSQLGYESAYGQSQSGRNDTNFFGITWFPGCPYPQGSARGIGG
                     SEGGFYMKFPNLNACYDYYGFMVASQSNFNQCVGNKDPGSCLLILGRGGYAAAGITEG
                     SSYYQGAISIIKSYNLTEYDAFAIKHWNSLPIKKTSLIAGKSKGNAKVLDRIIGRPVN
                     NGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGEDYNWATYGWQVIMNPKPSDLQAGDV
                     VNWQAGGALSPGIYGHTGIITDVSNSGQSFSTVEQNAEQGRIMARYQRGYNQAKIRSL
                     VRKVK"
     gene            10609..11121
                     /locus_tag="ACF3UE_002179"
     CDS             10609..11121
                     /locus_tag="ACF3UE_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HFD3635554.1"
                     /translation="MKKYYFFFLSCFCLFGLTSCGWIFSEEKTEVSLISKEKMIQAES
                     SSKESKRNQEDKTECNISEEIQYLLKNFGRKWVNYTDIYERNQSVKNYLTDRCIKENG
                     IDNDPHIQYKTIGRIHTITQDVIQSDQYLLFGEETTNEITRFVLLQIKVDQEVQKIDK
                     IKIYYVRSAY"
     gene            complement(11240..>11538)
                     /locus_tag="ACF3UE_002180"
     CDS             complement(11240..>11538)
                     /locus_tag="ACF3UE_002180"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3635555.1"
                     /translation="TPVTPETPDPETPVTPETPDPETPVTPENPEPDKPVSLKNTNSK
                     ILISEKNVSNTNSKSNNTLPQTGEKESSGVLAGLVILLASIAVGIKLNLKRKNI"
BASE COUNT         3852 a         1735 c         2467 g         3484 t
ORIGIN      
        1 tcttcacaaa cattcatata ataatagttt tatttaataa atacattgtt tttaaactaa
       61 tttctatatg tgttttgttg aactaactct tgacataaaa tttaaaagga tttatagttg
      121 ttaccgtagt agctactaaa agataaagtg aggattaatc aatggaaacg attattcaaa
      181 tcatgaaaaa atatgatttt tcagagatgg aaacaagagt gtataccaca ctattggaaa
      241 aaggcaatct tacaggatat gaagtaagta aagtctcagg tgtgccacgc tcgaaagtat
      301 ataacatttt ggaaaaacta ttaaaaaaga atttgattgt cgtcaataaa tcagaaccta
      361 aactttatca tgccatctcg gcaaatgagt ttttagagaa attagaaaaa agtgttaaaa
      421 atgatctctc ttttcttact caaaatctag ggatgatcaa agaaaaagat gaagaagaaa
      481 tgctgtggaa agttgatggc atcgagtatg ttctggataa agcagagcat ttggtgaaaa
      541 atgcaaaaga aagtttgctc atccaagttt ggcatgagaa cctcacggat tcactgctaa
      601 agacattgca gcaggctgaa aaaagagtcg ataaatttgt actgatttta ttcagttcta
      661 gccatgaata tgatcttccc ttagaaaagt attacattca tggttttgaa acagacaaac
      721 tcgctgactt tggggcaaga tggataaaca tcgtcgccga tgagcaagaa gtcgtgtttg
      781 gcaccattaa cgaagaactg caatcaaccg atgtcacttg gacaaaaaac cacgccatgg
      841 tcaatctagc aaaagaatat gtcaaacatg atgcatatac actaaaagtg attgcagaat
      901 cttctgaaga acttaaagca aaatatggtg aggactttga gggaatcaga aagatttact
      961 agtaggagga aatttttatg attcggaata ttttgctggc actaattgtc gcaatcaatc
     1021 tatattttat tatttacttt ctaagagacc ttttcaaaaa caaacaaaat ttcaaagaag
     1081 aaccagggga tatgcgtctg ttgcccttca cgtcatttat caccttcttt ctttcaacat
     1141 ttggcgtttc cgactttgct atcggaaccg tcctttatcc aaagttgaaa tgggtcagca
     1201 tgaaaaaact acccggaacg ttgaataccc aatgtgtcgt accggtagcc gtcatggcat
     1261 tgtcttatat cactgccatc aacgtagggg tcaagacact agctgtttgt attatctgcc
     1321 aaattatcgg tgcatattta ggaccaagat ttgtcgtgaa attaccagaa aaaacgatca
     1381 aactatttgt cggcatagga ttggtcattg ctgcattctt aatttttatg ggacaaatga
     1441 attggattcc ctcaaacgga acagccagtg aattgtatgg cggaaaatta atcttggcag
     1501 gatttttact ctttgtctat ggcgcattga acaatattgg cattggttct tatgcgctaa
     1561 cgatggtaac tgtctacttg ctaggcttga atccagttgc agcctttcct attatgatgg
     1621 gggcttgtac attctcagta ccgatcggca gtgtccaatt cattaaattt gatgaataca
     1681 gcagaaaaat cacacttttc acttcaacct tcggtgtatt aggggtattg gtcgctgtat
     1741 tcctagtcaa atctttagat acctatgtct tgaaatggat cgtaattttg gtcttactat
     1801 acagtgcata cacaatgttg ggcagtcaat taaaaaaagt ttcagcagct aattaaggag
     1861 cgattcaaat gttatttctt aaaaaagaag atattatcaa aagtttctca atgagagaag
     1921 ccatcgatgc agacaaaaaa gcattgtcat tgtattcagc aggaaaggca agtgtgcctc
     1981 ttcgcaccaa tatcgatgtg ccaaaaagca acggacaaag cttatatatg ccagcttatg
     2041 tagaaggtgg cgaaggtgcg ttaggtgtca aaatcgtttc cgtgtatcct gaaaacctca
     2101 agaaaaactt accaagtgta ccagccacga tgatcgtcct tgatccagaa acgggtatgg
     2161 tatccgcttg tttggatggt acctatttga cacaattaag aaccggcgct gttcaaggtg
     2221 cagcaacaga acttcttgca agagaagatg ctaaaatcgg cgcactgatc ggaaccggcg
     2281 gacaagcaca gtcgcaatta gaagcgatgt tgaccgttcg taaattagaa gaagttcgga
     2341 tttttgatat tgattttgac cgtgccagcc gatttgctga agaaatgatg caacagtttt
     2401 ctgtaacgat gcgcccaaca aaaaccagtc aagaatgcgt tgaaggagca gatatcatta
     2461 caagtgtgac cacttcaaaa cgtgcgacat tctctgctga gtgggtcaaa aaaggtgcgc
     2521 acatcaacgg agtcggtgct tacacaccgg aaatgtgtga aattccacga gaaataatca
     2581 aagccgcaga tgttgttatt tttgatacca tggacggtgt tctaaaagaa gctggggact
     2641 tcatttcacc gctgcaagat gggtatattc aaagagacag ttatcatggg gaactaggcc
     2701 aactgatcaa tgaagaattg atcggtcgga caagtggaga acaaatcaca attttcaaaa
     2761 cagttggttc ggctgtatta gatgtggtag ttgcgacaga aatcgttaat aaagctaaag
     2821 aaaataattt gggaaaattg atttattaaa taaaaagacc ggaagtaaac ctttaattag
     2881 tacatttata aaaagagaac aaaaaagact gtaatcaaaa tgcgattaca gctttttttt
     2941 gttttatttg ggaggagata gatcgtgttt atgactgtat cggatcattt aaaggtactt
     3001 ggttttatcc ctttatctag tagagggaag tatcaattgt atttgttaga tttaccaccc
     3061 tagcttttca ctgatgattg aaggaacata cgataaaaaa agtggtaagt atttttatga
     3121 tttttattct atgaaacttg atcctaaaac aaagaaaagt acgcagcacc ggatttattg
     3181 tacgcatgtt cctgtaaaag taatgtatcg tcgtgtgaga aattatttat acttcttacg
     3241 taaaaaacag caatcaagga acagaaaaaa tgcataatga ggaatatcaa gtgaaatttt
     3301 tatcagtttt gctctgtggt attgtgtatt gtcattagtt caatgagtat taacagggag
     3361 gaaaaagcaa atgaattttt ttcaaaatgt gtttaccgat tttgttgggg attttaagta
     3421 tttgattatg ttggcgatgc ttggtggtgc ggcatatatt gcctttgaac ggaaagcaag
     3481 caaagccatt ccattgattc ttgtgctagc agtagctgtt tggttagttg gagatacgtc
     3541 tggcgtattc aattggattt tggatcgtat gcggtcatgg gggcgataaa atgagtgaaa
     3601 tacgcaattg gacaaagatt tggtatatag agcgagtgtt ttataaattg tgggatgggg
     3661 tcgcgttacc tcgtcctgta acacaaacat ttgcgatatg gtttgggatt ggcttttttg
     3721 gggggatttt tcgaattttt ccatttgtta tggaacatac gattactcga caattttttt
     3781 gtccgtggtt atttgctttt ttaatgacac gaaaacaatt tcaaggaagg aagccttata
     3841 attatttggc ttcttttctt ttatttcagt gtcgttcaaa agaatccttt catggccaat
     3901 gggtaaagcc aatagaaaaa aaagaaatca aacgaggaat tcgttgtgta gtacgttatg
     3961 gaggtgaaaa ggatgcgact accaaaacta gtgcctaaga ttccttttta ttatttagaa
     4021 gacaatttag tttttggaga agaagatcgt gtgtacgctt attatgaatt cccaatgtat
     4081 tcatatagct tcgtgggaga agatcaggcg tatcaactcc aacaagcaat catgcgtctg
     4141 attcgtcaaa gtcattcttc gcatgttcgg ttcttttttt gtacaaacga agaaaaaatt
     4201 gaaaaaacga ttaaatcctc aaaagaattg gtgcgttcta aaggggaatt aaaaacgatt
     4261 gcctaccaac atttagaagg tgttcagcac attttagaag agctacatgg aaaatatatt
     4321 caaaatgttt gctggtatgt tgggattgag ctggtattag aagaaattgc tcccaaagaa
     4381 gctcattggt taaaagaatt tcgtattgcc gcaaaagatt tttttcaccg atccaatgcc
     4441 cgtttgtttg gagactttga aaccatccca aatgaaaaaa ttcaacgata taagcgattg
     4501 gagaatttat tgtataaccg gattagtaaa tactttcggt tacgaaaaac aacaccagaa
     4561 gacatggtgt ttttagtgga acatttagaa ggaaaaaaag aacaatcctt agatgaagtg
     4621 atgtatcgac caaatagctt taaagaagaa acgaatacgt atacgtatca ctatgatgta
     4681 ttgaatttgg ccagtgcagg aatcacagaa aagaaaaatt atctaatttt agaacaaggg
     4741 acagaaaaag aatatatcac gtatttatct ctttcacgta tgacccgtga tttggtattt
     4801 ccatttcaat cagagattta ttatttttta caatcggaat tggattttcc aatcgattct
     4861 tggttagatg tgaatctttt agataatcgt ttggccttgg cgaaagtacg tggcaaaaag
     4921 agtgatttat ctgatattta tgaaagtggt atgtcggttg gaaaagatgt aggaaacaat
     4981 gtacgcgaag cttaccaatc agccaatgag ttggaacaaa aattagaaga tacgcgagaa
     5041 gatttgtatg tattatcact aaacgttcgc gtgtcaggga agacctatga tgaaatgtta
     5101 aaacgtgtga gtgatgttcg caattttttt gatgtctatt ctatgtattt agaagtaccg
     5161 tgcaatgtac agctgctttt acattttgga agttatccag caggaaggcg agtgattgag
     5221 gattatcgtc aatatgtagg cgcagaattt attgctagtc ttggcattgg tgcgacacaa
     5281 caactaggag atggctgtgg tattccgatt ggatttaatg cagaaacagg aatcccagtg
     5341 tttattaaac catggttagc ggcacaagga ataaaaggaa cggttaccaa tactcttgcc
     5401 aaagcattaa ttggttcgct aggtggtggg aaatcattaa ctgagaatct cttgttattt
     5461 tggtcggtgt tgtttggcgc cttggctttt tgtatcgatc caaaatcgga acgttcaaat
     5521 tggtccgaag atttgccata ttttgccccc tacttaaaaa cagttaatat taccagtgag
     5581 aaagaaaata ttggtttact tgatccattt caattgatga gaagaaaaaa agatcaagaa
     5641 agtttagcat tggatgtgct cacctatatc acgggtgtaa gtattcggga cgaagaccgg
     5701 tttcctttgt tacaacgggc agttaaaact gtttctgatt ttgagggaac aaaaggatta
     5761 cttctagtaa ttcaggaatt atatgcacaa gaagcagcga ccgcacaacg cctggcaaag
     5821 catattgaaa gcttcaaaga actatctatt gcaggcctat tatttggaga tggcacgaac
     5881 caacaagggt taaatttgga tgccaaatgt aatctcgcac tggttcagga tttaacgtta
     5941 ccagatagtg aaactgtacc tgaggactat aactcttctg aaattttaag tattgcgatt
     6001 atgatgagtt tggctacgta tgcgctagat tttattaaac aaaatcgaaa aatttataaa
     6061 gcggttggct tagatgaaag ttgggcgtgg ttgaatgttg cgcaaggaaa aattttagga
     6121 gataaattgg ttcgtgaagg aagatctcgc aatgcaggga ttgatttttc aacacaaaac
     6181 acagatgatt taggtgatga aaagatgaga agtaaaattg ggttgaaatt catttttcgt
     6241 tcgaatgatc gcgaagaaat taccaaagca ttaagctttt gtggaatatc tgtcacagaa
     6301 gaaaatatcc agcgtgtaaa aaatctagaa aacggtgaat gtctgttttg tgacatccat
     6361 ggtaatattg gcattttgta tgtgtattat tggtttgaag atttattcca tgcatttgat
     6421 acacgaccgc caatggaaga aacctacgaa gaggaagaat ataaagacga gatattagaa
     6481 aaactggttg aagaaattga ggtgaattag atgaaacagt ggtattcaaa ggtttcattt
     6541 ttaattactc gccggaaact ggttttcata agtctagtca taatgatggg tgtttttttc
     6601 tttcacccat cattagtaga agcagctggt tggataaaag aaaccctagg cggcaaaaat
     6661 gccgtatatg attttgaaac atatccttta gataattata atttagattt ttttgtggat
     6721 acgtcgtgga attggttgcc gtggaaatgg ggtgaaggaa tttctaatac agttatttat
     6781 gggatatttg ccgttaccaa tattttatgg atgttaaatg tctacctgtg ttacttttta
     6841 gggtttcttg tccaagaagc ctttgaatta gattttcttt cagagttgat tggttcgtta
     6901 agtcatacaa ttcagaatat tgctggaatg aaccgtacag ggacattgag tcatggatta
     6961 gtccctttct ttggtggatt gttaattact ttagcaggtt gttcagtagt ttatcaagga
     7021 atagtgaaac aacaccctac gcaagctatt caacaagcgg tgacattttt gtttactttt
     7081 atttgttgcg gcgttttctt tatgaataca aacacatatt tagagaaagc taatggggta
     7141 caaaaagaaa tcaatagtga aatgttaacc attgccaaaa atctgttacc tgaacaaaaa
     7201 gaaaaaccag atgcaattaa ggccattcgt gagaatttat ttgccattca aattaagcaa
     7261 ccctggctag tgatgcaatt tggggatagt gatataaaaa cggttggtga agaacgtata
     7321 atcaatttat taaaagaatc accttatgat gaaggagaac agcgaaataa gcttgttgaa
     7381 gaagaagtaa ccaaacaaaa aaatggccat ctttcggtac aaaaagtgta tttgcgtttt
     7441 ggtatggtat ttttaacgct catcgtcaac attgtcatta gtatgagtgt tttggtatta
     7501 atcgttatct taattgcgtc gcaagtatta ttcttgttat ttataggatt cttacctgta
     7561 gcgatgattt tctcgttatt tccaaattca ggatcgttat taggtaatgc cttacagaaa
     7621 gtctttcaat tattgtttac aaaaatgggt attttactca ttttaaccat tactttttct
     7681 attagtcatg agttaaacca cttatccaag gacaaaggaa tgatttggac cagtttctta
     7741 caggtgacgt tatggttatc tgtctcgaca cgtgtcaatg aattattagg ttggatgaaa
     7801 attggtggcg tacaaacacg agctggggat cgaactggac gtttcttacg tggcatgatg
     7861 ttaggtacaa tgggtcaaaa aatgatacga ggaattggtg aaaattttgt tgggggtact
     7921 gccggaggtg tagctggcca aatgatttcc aaatctatga gtggtcaacg aagtatagct
     7981 tctacacctc ttatagagcg agtaggaaaa aaagtttcag ctatgacaga attaccggca
     8041 acgattgaaa gtagggcaga acaatggaag cggacaattc agtatgtccc aaccaatgcc
     8101 caatacaaag cacaaaaaat gaaatacgat tatttctctg ggcgaatgaa tgagtcggaa
     8161 cgacaaacac gagcgcgtaa ccttgcgaat gagcgacaga agaattttta tgaagcacga
     8221 aaagatgcat tgcaattaga gcaacaagag agaaaacaac gagcgatgcg ttcaatggcg
     8281 catcaaacag gaaaaacaca agtgacttct ggtaaattac aaacacggaa aagtgcaatg
     8341 attggtcgaa cagaacaatt tcctacgata gaaaaaagaa gtaacatttc aaatatagct
     8401 aaaaataaga aattgtcgaa gcaggaacat ccgattcatg aacgaagtac gaatcgaaag
     8461 attgaaactc cggttcgttg gacttcgact tctcgtcaaa acgcgagaaa aggtagaact
     8521 aaaaaagaat aaggaggagg gctatgtttc ctcggaagaa aaaactgtct attctctctg
     8581 aacaagaaac aagactaaaa ggaaagaaag acaagaaaaa agaaagctat aagggagcgc
     8641 gaaaaaggcg cttccttttt tttgtaggct ggagcttttt ggtttttagt gtttgttttg
     8701 gagtttataa taatttaact tctcaagata cgcatacaat ccatgaaaca aaagtcattg
     8761 ataaacaatt aaaagatatg actggaatag aaagttatgt gaaaaatttt gcatttttgt
     8821 attttacagt gagtcttgaa agcgaccaac aaataaatcg atcaaaagca gtagaaagtt
     8881 atttagctga tgggctgcaa atggataatg aaatagataa agacatagaa acgaatgtaa
     8941 aagttaaaaa tgtctcgatt tgggcaatag aggaacatga atcaaaaaaa catacatttg
     9001 tggttatgtt tcatgtctta ttagagatag aaaaagaatt caaagagcgt gtgtataagg
     9061 tggaggtata tcgaaacgaa ttatcatatg ccatagtgaa attgcctatt gtagcgagta
     9121 atgttaaaaa agcaacgatt aaagtagaca ctcggttcga aacaacgagc atttctcgaa
     9181 aagaacagga agaattagag aaattcttat ataccttctt tcgtatttat cctaaagcaa
     9241 acgcagaaga attaaaatat tatgggacaa ctcttttacc aattcaacag cctttagcct
     9301 ttgaagaact atcgaatttg caagtcgcaa aaaaagaggg tagatatgag attcattgta
     9361 atattttgta tcaagatcaa gaaacgcacc tttggtttac catgtactat gaaatgtcta
     9421 tgaaacaatt agagaatggg aactttcgaa ttgaggcgat tcattagtga aaaagatttt
     9481 tttatttagt ggcatctgta tgatgagttg tctgttttta ttatttgcga taattagcat
     9541 gtctagtggt gaatcgaagc acatggattc agcagttggt gttactcata cgggagaata
     9601 tatcgaaacc ttacctattt tttcagagat caaagggcgt ggtccgataa cagatgaaca
     9661 tgcccaagca gcagttggtg cagctgtaaa gtatcagtta ttaccgagtg tgattctttc
     9721 tcaattagga tatgaatcag cttatgggca gtcacaatct ggaagaaacg atacgaactt
     9781 ttttgggatt acgtggtttc ctggttgtcc ctatccacaa ggttctgcac gtgggattgg
     9841 tggttctgaa ggtggtttct atatgaagtt tccgaacctg aatgcttgtt atgactatta
     9901 tggatttatg gtggcgagtc aaagcaactt taatcaatgt gtgggcaata aagatcctgg
     9961 aagttgttta ttgattctag gtcgtggagg ttatgcggcg gcaggtatca ccgaaggcag
    10021 ttcgtattat caaggcgcaa taagtatcat aaagtcctat aacttaacgg aatatgatgc
    10081 ctttgcgatc aagcattgga atagcctacc aatcaaaaaa acttcgctta ttgcaggaaa
    10141 aagtaaaggc aatgcgaagg ttttggatcg gatcattgga cgacccgtaa ataatgggga
    10201 atgttatggt ggtacggcat ggtatgtatc tcaactaggt ggcccacagt taatgggttc
    10261 tggacacatg tttgcgatgt taatagggga agattataac tgggcaacct atggttggca
    10321 agtgatcatg aatccaaagc ccagtgactt acaagcagga gatgtggtca attggcaagc
    10381 aggtggtgca ttgtctcctg gaatctatgg ccacacgggt atcataacag atgtctcaaa
    10441 tagtggacaa agtttctcca ccgtagaaca gaacgccgag caggggcgaa ttatggcacg
    10501 gtatcaacgc ggctataacc aagcgaaaat tcgaagtctg gttcggaaag tgaaataaaa
    10561 gaattctttc gatgaaaatt tttagtagaa aagggagaag gatcgattgt gaaaaagtat
    10621 tattttttct ttctaagttg tttttgtttg tttggactta ctagttgtgg gtggattttt
    10681 tctgaagaaa aaacagaagt ttccttaata tcaaaagaaa agatgataca agcagaaagt
    10741 tcaagtaaag aaagcaaaag aaatcaggaa gacaaaacag aatgcaatat ttctgaagaa
    10801 atccaatatt tgttaaagaa ttttggaaga aaatgggtga attacacgga tatatacgaa
    10861 cgaaatcaat ctgtaaaaaa ctatttaacc gatcgttgta taaaagaaaa tgggattgac
    10921 aacgatccac atatacaata taaaacaatt ggccgtattc atactatcac acaagatgta
    10981 atccaatcgg atcaatattt attatttgga gaagaaacaa caaatgagat aactcggttt
    11041 gtgttacttc aaatcaaggt ggatcaagaa gtgcagaaga ttgataaaat caagatttat
    11101 tatgtaagaa gtgcatatta aaataaaaaa ggaattgtgg aaattgtttg taattaaatc
    11161 gaacagtgat tatttatttt aaattgaaaa cagagatagg atgaatactt attctatctc
    11221 tgttttcttt tggactaatc tagatatttt ttcgttttaa atttaattta atacccactg
    11281 caatagaagc taataaaata actaatccag ctaaaactcc tgatgattct ttttcaccag
    11341 tttggggaag agtattattt gactttgaat tagtatttga aacattcttc tctgatatta
    11401 aaattttaga gttagtgttt tttaaagaca ctggtttatc aggctcaggg ttctcaggcg
    11461 ttactggagt ttccggatct ggagtctcag gtgttaccgg agtttctgga tctggagtct
    11521 caggtgttac cggagttt
//
LOCUS       DAXLPC010000083        11150 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.084, whole genome shotgun sequence.
ACCESSION   DAXLPC010000083 DAXLPC010000000
VERSION     DAXLPC010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11150
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.084"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            6..305
                     /locus_tag="ACF3UE_002181"
     CDS             6..305
                     /locus_tag="ACF3UE_002181"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3635556.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACF3UE_002182"
     CDS             378..1739
                     /locus_tag="ACF3UE_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFD3635557.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFLSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLLFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGILTMPIYLYGATYLAPILSDSAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACF3UE_002183"
     CDS             1761..2021
                     /locus_tag="ACF3UE_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635558.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACF3UE_002184"
     CDS             2035..2787
                     /locus_tag="ACF3UE_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFD3635559.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACF3UE_002185"
     CDS             complement(2881..3486)
                     /locus_tag="ACF3UE_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3635560.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIEQAREWTDHLLTK"
     gene            complement(3542..4516)
                     /locus_tag="ACF3UE_002186"
     CDS             complement(3542..4516)
                     /locus_tag="ACF3UE_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFD3635561.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DCPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4894..5613)
                     /locus_tag="ACF3UE_002187"
     CDS             complement(4894..5613)
                     /locus_tag="ACF3UE_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3635562.1"
                     /translation="MPKYEEIANILRERIRSKEYPPDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACF3UE_002188"
     CDS             complement(5740..7011)
                     /gene="celB"
                     /locus_tag="ACF3UE_002188"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFD3635563.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7164..8561
                     /locus_tag="ACF3UE_002189"
     CDS             7164..8561
                     /locus_tag="ACF3UE_002189"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3635564.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWNHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSRLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKAIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGTIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8642..9082
                     /locus_tag="ACF3UE_002190"
     CDS             8642..9082
                     /locus_tag="ACF3UE_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFD3635565.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9229..9555
                     /locus_tag="ACF3UE_002191"
     CDS             9229..9555
                     /locus_tag="ACF3UE_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3635566.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9556..10305
                     /locus_tag="ACF3UE_002192"
     CDS             9556..10305
                     /locus_tag="ACF3UE_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFD3635567.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10331..10741)
                     /locus_tag="ACF3UE_002193"
     CDS             complement(10331..10741)
                     /locus_tag="ACF3UE_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFD3635568.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNK"
BASE COUNT         3538 a         1948 c         2291 g         3373 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttcgaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcctgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtctta ttgctgcttt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattacca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcctc acgatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgattcagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaaggaccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcaaaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgggagat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc tcgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccaatc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa aaatgaagta gcatgaagag
     3541 attattcacg ttttttattt gcatcacttg tatcgaaagg acggacatag gcttcaatgg
     3601 cttcacgacg ttcttctaag aatggaggaa gagatagttt ttctcctgct gattctgctg
     3661 gttcatcttc aaggaatcca ggacaatcag ttgctaattc aaacagtacg tgatgagcgg
     3721 ctaggaagta ctcagattgg aaatagaaac gatcgacgaa accagaattt ggcaattcaa
     3781 tcttattgat tacttgaatc cagtattcca atgcttcttt gtctgctaca cgcaatgcta
     3841 agtgatggat atttccaaat ccttcgattg cttttggcaa gtctgtccga tgttcaataa
     3901 tgatgcttgc accatttccg ccttcaccga tttcaaataa gtagaaatct cctgaatggt
     3961 ctgtttcttt gaatcctaag attttttcaa gaatcaagcg gatatgctct aattgactga
     4021 cacggacaaa gacaggtcca agtcctgtga tcgcaaactc tgtcggtaca ttgctgtttt
     4081 tccaaggaat gccagctgct acaccttgat tgttttcgtc agagatcaat tgataatact
     4141 gattatcgaa atcttcaaat tcgatatatt ttttgccgaa acgttcattg attgctgaat
     4201 gagtaacgtc atatttttca aaacgttcca accaaaagtc taatgctgcg tcacttggca
     4261 cacggaaaga agcacgagag atcgtatctg ttcctttttt tccttttggc tgatttggaa
     4321 aatcaaagaa agtcatatct gttcctggcg caccagtatc gtctgtaaag taaagatggt
     4381 aagtttcgat gtcatcttgg ttaactgttt ttttgattaa gcgcattcct aaaatatctg
     4441 taaaaaagcg gtagattttt gtagcgctag atgtcattgc tgtgacgtgg tgaattcctc
     4501 tgatttgtgt atccatgata aatttcctcc tgtcaactta caaaaagtaa gtagttgatt
     4561 tagacatagt atagagggtg catctctatt ttgcaattaa tttgtcttct aaagtatcag
     4621 gaaggaatca agaatggaaa agaggaggga cggatcaata aaataaaaag acttacgact
     4681 agctgtatcg atttcaaaaa aactagcttt aaaaagctaa ctttagaatc attacgggtg
     4741 gtcataagtc tttttatgct gagttatttt ttcatttttg agctaatgct taggatagga
     4801 tagaatgttg atttcacgat ctcttcttgt tacttgaaac tgcttactac tgtcacgatc
     4861 tcttggtaaa cggctttttc acaacctctt catttaagtt gaacgcacat ccagcacaga
     4921 atagttccga acatcaaatc ggtttcggct ggaagaatat tcaatcggct gtccatcttt
     4981 gagatagacg acttgctgaa cttccagtac aggatcgttt tctgcacagt tcaaatattg
     5041 ctgatcatat tcatcacttt tatctgcaga aatagcacga taagcccctg caaaatggac
     5101 attcaattct tgatgaagat gatcatagat agaggctaac aaatgttctt tttttaaacc
     5161 cggcacaaga tggactggca taaaagtatg ctctaaaaca tatggctcgc catctaagat
     5221 ccttaaccgg tgaatattgt agacaggttg ctcggcatcg atcatcaatc gttcttggat
     5281 atattgatta gggaattcaa catcaaaatg aatgatttga ctcttcaaag aacgatgtct
     5341 gcgtttcatt tggagactca aaccttcata ctcgttagcg ggcgatgtgt ctttttgcat
     5401 aaatggatga ttcaagattt tcgttcctga tcctcgctgc gaatagacaa gtccttccat
     5461 tgctaagata ttgatggctt ttttgattgt catccggctc gcaccaaatt ctttgaccaa
     5521 gtccacttga ttaggcaaaa aactatcggg aggatactct tttgaacgga tacgttctct
     5581 taaaatattt gcgatttctt cgtattttgg cacgttattc acctcttcta gagtataacg
     5641 aaagattatg cttccgacaa ctcgaagtag catctggaac attgtttatt cgaaaaaaga
     5701 ggtcgtgaca agtttttgtc acaacccctt aatgatctat taagcaatat ctaaatctgg
     5761 ttgtttatct agtactttca ggaatgggta ccagataaag gcaacgatga caaagtcgat
     5821 gacttgcagc ataccaccaa gccatgaatt tgttgctaag acaccgcttg caatgattgg
     5881 cacagtccat ggaacagaga cgccagttgg tgcagggaca agtccagcag ccattaccaa
     5941 ataattgaac gtcgttacga ttagaggtgc cacaacccaa ggaataagga ttgttgcatt
     6001 caatacgatc ggtagaccga agatcgctgg ttcatttaca ttgaaaatac caggtgctaa
     6061 agctaatcgt ccaacatcac gatactgttt ctttttaaga acaaaggcca tcaataaaac
     6121 gacagctaaa gtcattccag agccaccaat accaacagtg aaggtttcca tgaatggttt
     6181 tgtgatgatg tgtggtaatt cttttccatg ttgataagct tctaagttat caagcatcag
     6241 tgtattccaa atcgggtcca ttacagagtt gacgatgatt tgtccgtgaa gtccgaagaa
     6301 ccataagaat tggacaaaga acaaagcaat caatgttgca ggtaaactac ttcccaaacc
     6361 agttaatggt ttttggatca cttcataaac gacgtcatgt aagttagcat tgaaaatacc
     6421 agtcatcaca gcattgatta ctaagaaaat agttagtgtc actacagcag ggatcaaagc
     6481 ggcaaatgat tttgttactg caggcggaac tccatcaggc attttgatct gccagccgcg
     6541 tttcgtgatt ctgcagtaga tttctccagc caagaaagca gcgatcattc caatgaacat
     6601 tccttttgcg ccaagacgat caagtgaaag cacaccagtc acatcttcac cgccagcggt
     6661 tttcattgca aaaggcgtaa gaatcaagaa gctggcaaaa gacacggcac caccgaaaat
     6721 accttcaacg tcataagatt ttgataaata atagccgata ccaaaagtaa caaaaaccga
     6781 catgatgctc attgttgcat tttgcccatt accgaataag ttcgataaag ttccctttgt
     6841 tgcgtcactg aaaaaaggca agttattgat aacgacaacg atcgaaccga acatcgttaa
     6901 agggaaggaa agcatgaaag catcccgcag cactgtaagg taacgatttt gccctaataa
     6961 attagctaag ggcatgattt tctcagaaag cttgtccata aaaccgttca tttttattca
     7021 cctcaaattt atttgcaatc gattacatac aaagtataac gccaaaaatt ttaaatgtct
     7081 agtcattttc ataaaaagta ttgatttatt ttttagggtt cgttatgatt acgatatcaa
     7141 gaaaaaagag aggaagtaaa aaaatgaaaa cctacacatt cccagaaaat ttttggtggg
     7201 gttctgctgc tagcggaccg caaacagaag gaagagtaag tgatgatggt aaaggagaaa
     7261 atatttggaa tcattggtat gaattagagc ctgaaaaatt cttcgatcaa gtaggacctg
     7321 aaaaaacttc gcaagtttac acaaaataca aagaagatgt tcagttaatg aaagaaactg
     7381 gccataacac atttcgtaca tctatccaat ggagtcgttt gattccagaa gggacaggtg
     7441 aaatcaatca aaaagctgtt tctttttatc gagattattt tactgaattg ctggataatg
     7501 gtatcgaacc ttttgtgaac ctttaccatt tcgatatgcc actaccactg caagaaaaag
     7561 gcgggtggtt atcaagagaa acggtcgacg cttatgtttc ttatgcagca gcgtgctttg
     7621 aactgtttgg agatctggtc aaaaaatggt ttactcataa tgaaccaatc gtacctgtag
     7681 aaggaggcta cttgtatcaa ttccactatc caaatcatat caatatgaaa gaagcggtcc
     7741 aagtaggcta tcatgagaat ctagcaagcg caaaggcaat caaagcctac catgaaggcg
     7801 gacatgatgg tgagatcgga atcatcttga atctgacacc aagctatccg agagatgaaa
     7861 cgaacccaga agatgtaaaa gcggcgaaga tcgctgacgc attcttcaac cgatcattcc
     7921 ttgaccctgc agtgaaagga gagtttccac aagagttgat cgaaattgtc aaagaattgg
     7981 ctataatgcc agagatccat gaaggagacc tagaactcat ccgtgaaaac acgattgacc
     8041 tgctaggaat caattactat cagcctcgtc gaatcaaagc aaaagaaact ccaatcaatc
     8101 acgaacatag ccccatgcca gatgattatt ttgataatta cgacatgccc aataaaaaaa
     8161 tgaatccata tcgtggatgg gaaatttacg aaaaaggaat ctatgatatt ttaacgaata
     8221 caagagaaaa ctatggtaat atcaaatgct atatttctga aaatgggatg ggggtcgaag
     8281 gagaagaacg atttgttaac agcgaaggaa ctattgaaga tgattaccgg attgagtttg
     8341 ttacggatca tttgaaatac gtccatcaag caatccaaga aggaaccaat tgtgtgggtt
     8401 accacatgtg gacatgtatg gacaactggt cttggacaaa tgcttataag aatcgctatg
     8461 gctttatcgc tgttgatttg gcacaagacg gtaaacggac gatcaaaaaa tcaggtcgct
     8521 ggtttaaaac ggtctctgaa aaaaacggat ttgatgcctg atattttttg ataaaacgtt
     8581 cacaaaatgt ttgttctaac actgtaatcg tgctacacta acagtgaagg aggcgtttac
     8641 aatggtagat acttatcgta atattttagt agcaattgat ggttctgaaa aggcagaaaa
     8701 agcatttctt gaggcaatca cgattgccaa acgaaatcag gcaacgttgc acatcctgta
     8761 tgtcaatgaa gtaacaggca attactttgg tgattttgca tttgttacaa caagccttca
     8821 ggaagaattg gatgaggttg cggaaaacca gatgaaagaa catcgaaact tggcaattga
     8881 aaaaggcttg acagatatcg agacatatgt tctttacggt tatccaaaga cactgattgc
     8941 taatttccat gaatcgaaag aaccaatcga tctgattgtc atgggggcga caggtctgaa
     9001 tgcggtagaa cgtgcactag taggttccac tacttcctat gtagtcaacc acgcatcatg
     9061 taacgtcatg gttgtaaaat aaataaatta agggaacaga aagcaaaaaa gcataacgct
     9121 tcttttgctt tctgttcctt taattttttg taaaaaatta ctttacctga tgaagtaatc
     9181 atgctattct aattacaacg acagatggag taatatggag gaaagaaaat gatttcaagt
     9241 gatggaatac gcggatacaa tgatgcgatt attttatcga tccttaacaa aaacgattct
     9301 tatggatatg aaatttctaa aacgattcgt gagaggacaa atgattccta tgtgatcaaa
     9361 gagacaacac tttactccgt ttttgcccgt ttagaaaaga atcaactgat tgtttcgtat
     9421 cctggagaag tgactcatgg aaaaaagcgg acatattata aaatcactga aatagggcgt
     9481 aatcttttag aagaaaaaaa gcaagagtgg ctgacgacga aagacgtagt cgatcaattt
     9541 ttggagggaa attaaatgga tacaatccgt aattatttag acagtctttt tatcggagta
     9601 cctcaaagta ccgagataga taagctgaaa actgatttgt tggcaaatat ggaagaccat
     9661 tatcatgaat tgatgggaga aggaaaaaat gaacaggagg ccatcggtac agtaatttcg
     9721 acatttggtt caatcgatga attattagaa gaactagatg tcgaaaaaaa acatcaagct
     9781 gacgagacgg aaacaaacac agcttctatt tatttaagcg aagcagaaaa ctactggaaa
     9841 gaatacagag cggcaagtct ccaagtggca tcaggtgttc tattcattag cttatctttt
     9901 gcaagttttc ttttcttttg ttcagcaggg tatgtgttca tgggtatttc ttgtctgatt
     9961 ttcggtatag cattagctgt cggttttttt attgcttctg gtatgaaaat cacacgttta
    10021 aatcactttt tgcaccatcg gaaaatacct gaaaaagtat tagcagaagc aaaagaaaaa
    10081 gaagaagagt atcagcgaag ttttggcttc tcactgattg caggaattgg attatgtatt
    10141 ttttcacttt tcccactttt ggcttcttta atgtggtata tggatggtag tatcggtgcc
    10201 tctatatttt ttgttacggt aggaacggga gtcttcttga tcatttatgg cagtctggtc
    10261 cgtcattctt atcgtcaatt cactcaaagt gcttattact ggtgaatgta ttcagatttg
    10321 taaaaatatt ttatttattg cttacccatg taaaatcgtt atagacagat ttcagttgac
    10381 ttctgcgcca ttgtacaggg ataaaaagac gcatactatc ttcattgaat ccgactaata
    10441 atttctttcc gtcagtaatg atgggacgtt gtaacaaagt aaaatgcgag acgatcagat
    10501 cgacaagctc tgaggtcgta cattggtcga tttgatcttt caaattttta taatcaatcg
    10561 agcgtttagc taatagatcg tcaaatccgt tttctgttaa tgacaataaa taaaatatct
    10621 ctttccttgt taaaggctgt ttaggtgtga aaattcgttc tctgtaaggc atttgatggt
    10681 ctttcagcca gtttgccatc agatggtaac tatgtgtgcg agaagaatag atcgtaagca
    10741 taaaaaaact ccttaaatag tccattaatt tgttagatct gttgagataa ataataggta
    10801 aggagctgtg cataagcatt gatcaaaaca acccaaacat cattagaaat aactttctaa
    10861 agtcttaaac ttgcgacgag aaacaactag actaatagaa aaaatgtctt agccatttgg
    10921 cttcctgttt gtttttttgc ttatgctgca gctcctcggg aaagggttct aacaatttga
    10981 agaaggttga tgattgatct agtttaaatt gtgtgaaatt tgaaatctgg tgtttttact
    11041 agatgaatca cctaacaact atgattataa cttatagaac ttctgttttg tacttggttt
    11101 tgttatagtt gttataaagt tttattttat tacagaacat ttttaattaa
//
LOCUS       DAXLPC010000084        10846 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.085, whole genome shotgun sequence.
ACCESSION   DAXLPC010000084 DAXLPC010000000
VERSION     DAXLPC010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10846
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.085"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(135..1715)
                     /locus_tag="ACF3UE_002194"
     CDS             complement(135..1715)
                     /locus_tag="ACF3UE_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFD3635569.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2116..3492)
                     /locus_tag="ACF3UE_002195"
     CDS             complement(2116..3492)
                     /locus_tag="ACF3UE_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFD3635570.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(3620..4708)
                     /locus_tag="ACF3UE_002196"
     CDS             complement(3620..4708)
                     /locus_tag="ACF3UE_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFD3635571.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            4880..5314
                     /locus_tag="ACF3UE_002197"
     CDS             4880..5314
                     /locus_tag="ACF3UE_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3635572.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5392..5925)
                     /locus_tag="ACF3UE_002198"
     CDS             complement(5392..5925)
                     /locus_tag="ACF3UE_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFD3635573.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6019..7197)
                     /gene="mutY"
                     /locus_tag="ACF3UE_002199"
     CDS             complement(6019..7197)
                     /gene="mutY"
                     /locus_tag="ACF3UE_002199"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFD3635574.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7190..7987)
                     /gene="recX"
                     /locus_tag="ACF3UE_002200"
     CDS             complement(7190..7987)
                     /gene="recX"
                     /locus_tag="ACF3UE_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFD3635575.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8094..9476
                     /gene="rlmD"
                     /locus_tag="ACF3UE_002201"
     CDS             8094..9476
                     /gene="rlmD"
                     /locus_tag="ACF3UE_002201"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFD3635576.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(9650..10228)
                     /locus_tag="ACF3UE_002202"
     CDS             complement(9650..10228)
                     /locus_tag="ACF3UE_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFD3635577.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            10550..>10846
                     /locus_tag="ACF3UE_002203"
     CDS             10550..>10846
                     /locus_tag="ACF3UE_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFD3635578.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGEYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFN"
BASE COUNT         3231 a         2186 c         1874 g         3555 t
ORIGIN      
        1 acatttctat gattttaata tagtaaaaag agccgtcacg gaaaatccgt cacggctcta
       61 aacaaaatat gagaggctgt ttttgtttgg ctattcttat tacttgatgc agggcagctt
      121 gtgtcaagac ttctttacat caaacttttt aattttacat tgggatattt atccgcaaac
      181 cagcgttctg caaattggtt ctcgaataag aacaacggtt ggtcgaaacg gtcacgagcc
      241 aagatattgc gacttgaact catcttctca tccaaatctt ctggatcgat ccagcgagcg
      301 attttgtgtc ccattggaga catgattact tcggcgttat actcatttaa catacgatat
      361 tggaatactt cgaattgtag ctgaccaaca gctccaatga tatattcttc cgttagatat
      421 gttttataaa gctgaatcgc tccttcttga actaattgat agattccttt gtggaaggat
      481 ttttgtttca tgacattttt tgcagtcact ttcataaaca gctctggagt aaatgaaggg
      541 agttcttcat aagcaacttt tagttttcct tcgaacaatg tatccccaat ctgataattg
      601 cctgtatcat atacaccgat gatatcgcct gctactgctt tttcgacgtt ttctctcgaa
      661 tctgccataa attgtgtgac attgcttaat ttcagttttt tatttgtacg ttccaaccag
      721 acatccattc ctcgttcgaa tgttccagaa cagattcgga caaaagcgat tcggtcacga
      781 tgggctggat tcatatttgc ttggatcttg aatacgaaac ctgaaaattc ttcctcataa
      841 ggacttacca tctgatcatc ttgtgttttg tgtccataag gagctggtgc caattcaacg
      901 aaagtctcta aaaaagtctg tacaccgaag ttagtcaatg cagaaccaaa aaatactggt
      961 gtctgatcgc cacgagcaat tttttcttga ttaaatgcat ctccagcctc tttgattagt
     1021 tctacttctt ctaagacttg ttcatataag gaattttcag ttagaggatg attttcggga
     1081 agcagtccat cttcatccaa ttctactaat cgttcatcct gataattttc cggacgataa
     1141 aactctacac gattatggta gatatcataa agaccttcta gccctttacc cataccgatt
     1201 ggccaattca tcggataaga ttcgatatct aatagctctt ctaattcttc taacaattcc
     1261 aatggttcac gaccatcacg atctagtttg ttgataaaag taaatatcgg gatgccacgt
     1321 ttttttacaa cttggaataa tttctttgtc tgtgcttcga tcccttttgc actatcgatt
     1381 accatgaccg cactatccac ggccatcaaa gtacgataag tatcttcaga aaaatcttca
     1441 tgtcctggtg tatccaagat atttactcgt ttcccttgat aatcaaactg cataacagaa
     1501 ctagtaacag aaatcccacg ttgtttctcg atttccatcc agtctgattt ggcaaaatta
     1561 cctgtttttt tgccttttac ggtcccggct tgacggatag ccccaccaaa caatagtaat
     1621 tgttctgtaa tcgttgtttt cccagcatcc ggatgggaaa tgatcgcaaa agttctgcga
     1681 ttgtccactt gttgctttaa ttttggatta ttcataacct aactccattt cttccattca
     1741 attatttata ttttctctag gcacagattg tccgatctct taaagaaaga caatttcata
     1801 tagggctgtg acaaaagccg tgtagcagtc tctttttccg agtaaacggc gttctagaga
     1861 cagcctatca gcaataagcc cacccaagcc aaaaatacga aaagctgttt ttgcttggct
     1921 gctcttatta cttaatgcag gatagctttt tcacaacctt tgtcaactac tacaactgaa
     1981 tcagtatagc atggattcag cgaatgaaaa agccaccaaa ccataagagt caaatatttt
     2041 tttgtcagct gactaaaaga aaagacgtgt tgcttgttta ttcaagcaac acgtctttca
     2101 taaccaagtt tccaattatc ttcttggctc gtcatcttcg aattcttttc tgaagtatct
     2161 tcgttcttct tcaggttccg cttctgtttc ttccggatca tgaaaaatga cacggatttt
     2221 aaggattcga gaaccttcca tttcttcaga aaccagcgta atattatcga catcaaacga
     2281 taacttttcg ccttcatccg gaatcatgcc taatgctgta atcaaataac cagccatcgt
     2341 atctacatca ctcatatgca gatcactgtc aaaagcttca ttgaactcat caatcagcat
     2401 acgtccttgg atgatatatt cgtgttcatc gattttttca taaagattct caacttcatc
     2461 tgattcatca tcgatttctc cgacgatttc ttctaaaagg tcttctagtg ttgctaaccc
     2521 aacgacgccg ccatattcat ctaataaaat agccatctga ttctgcgtct ttttcatttc
     2581 atataacaga tcatcaataa agaccgtttc aggaacgaat aaaggctcct gcatgatttt
     2641 cttgatatct aaattatcaa agccgaattt atgggcagct tttagtaaat tctttgtatg
     2701 aaggattccg actactttat ctttgtcttc gttataaaca gggattcttg aatagttttc
     2761 ggataaaact tcattcacat tttcttccac agtgtcgttg atatcaatca taaatgcatc
     2821 cgttcgtggg accatgactt ctcgggcaac tttcgtatca agagaaaaaa ccccttggag
     2881 catttctaat tcttcattat tcaatacgcc ttcgttttca agcatataac gcatttcatc
     2941 tctggtcatt tttgaatctt catcatcaaa agtcatcggc gtgatacgcg ccaataaact
     3001 tgtggaagca gaaagcagcc agacgaaggg cttagctact acaccaatca agcgtatcag
     3061 ccctgaagtg aactttgcga cttcttctga tttatttaaa gcaatacgtt tagggtacaa
     3121 ttctccaaaa acaatcgata cataggtcaa aatagccagc acaatgatat ttgcaatatt
     3181 ttttgccgct gtgccgccac ctaataccgg agctaaccgt tccgataaag tattagctag
     3241 tgaagcacca gacaaaatgt tgaccaaagt gattcctact tggattgtcg ataggaaatt
     3301 atttggattc tgcaatattt ttaaaagctt ttgagatttc acatctcctt catcagcttt
     3361 ttgctcgatt cgattcttat tgatcgaaac aacagcaatt tcggaagctg ctaaaaaagc
     3421 attgatcaat gtcaaaacga tcaataataa aatctgcgct aacagcgact gactctcagg
     3481 gtcagcattc ataatcgcat tctctcctta taaaattaat ttttagttta cgatagaaaa
     3541 aaacgtggca ctatagccac gttaaaatgg tatcacaaag caattttctt tgcaataaaa
     3601 acaagtgtac taaaactacc tacgaggtcg tagcaatttt cttcttgttt tcattttgct
     3661 tgtcttcttt gacgattttg attatatagg aaatgatcgt cttgcagatt gcgtaaaaag
     3721 gaacacctaa gaagatacca agcaatccgg caatatttcc agctactaga agaacgataa
     3781 tgatcgttaa tggatggatt ttcagtgatt tcccaattac attaggataa atgatattcc
     3841 catccaactg ttggacgatt agcacaacca cacaacaaag taatgctttt accggatcat
     3901 tgaagactgt tactagaaat gcaggtgcta gtcctagata aggtcctaaa tatggaatta
     3961 ggtttgtcaa tcccgcaatg accccaaata agaaagcata atccacacca attaccatat
     4021 atcctaaaaa tgtgaaggta ccaacgaata aacattcgat tgcttgtccg ctaatgtaat
     4081 tagccaatgt tttattcagt tgccccaata actccacaat ttggtttctt cttttttctg
     4141 ggaaaaactg ttggatgttt ggcactagtt tttctccgtc tttcaacata tagaacaaga
     4201 tgaatggtgc tgtaatgatt actacggttg ccgaagcgat cgttccaacg atcgaaccta
     4261 aactattgga tactccacta aggaattgct gaatgattgt cccgtaagaa atgtctaatt
     4321 gctcaaaata tttattgata tctacttcct tgaacaaagg caattcggct acctctttta
     4381 accagctttc tacctgtttg atgaaatcag gcatattaga tgccaatgag gaaatttgct
     4441 gtactagact tgggatgaca ctaagtaaaa tccaaataat tgctgcaact aaaaggagca
     4501 gcacaattgc gacagcccat attcttttga tttttgcttt catcaacagc ttgacaatag
     4561 gattcaataa atagtaaaga aagcctgcaa tcagtacagg tgcaaataac gtggaaaaaa
     4621 atgtcccgat cggttcgaaa ataaagttta tttctgatga aatcatgatc aatgcagcta
     4681 tgatcaataa ttcaagcgac caaaacatta gtttagactg tctaagtttt tcaaacaata
     4741 gatttcctcc tttctttctt actagtatat attatattcg ttaaaaattc ttttattctt
     4801 tttttatttt tgaaaacttg ccatactttt tatttgtttt attttccagt atactatacg
     4861 aaaggaaggt ggctagacca tgaaagttgt acaaacaaaa gatacaatga gcaatattta
     4921 cttagatgct gtacggatca ggcatcaagt ttttgtagtc gaacagggtg tgcctttgtc
     4981 tcgagaaata gacaaagatg aagcccattg tatccacttc gtcctgtact cagataaaaa
     5041 agaaccgcaa ggaactgtac gtcttttgcc tttagaaaac ggaaaaatga aattacagcg
     5101 gatggcgatt ctttctgaat acagacacca agggttagga aaaatattga ttgaagaagc
     5161 agaaaacttt gctaagaatc aaggctataa tacgatttta ttaggggcac agtccacagc
     5221 tgaaactttt tacgaaaaac taggatatac agcttacggc gatccttttg aagatgctgg
     5281 catgcctcat atttatatga aaaagacttt ataaaaattt atttcgaaaa aagcaaaaaa
     5341 cagcaagctt ttgagaaaaa tctctcactg gcttactgtt cttttttgtg tttacttacg
     5401 cgacaattgc ttgtaacggt tataccaaat atcaatatag ccttccgaga acgggccatc
     5461 tccattattg atccagtcaa ccagaatctt cacattttct tttaggatga agtcaatatc
     5521 gttcgggtaa ttcatcattt tgctgtgcat ctcatattca tcgacatcca atagtcgttt
     5581 ctcgccgtca ggaaatacct tgatatccaa gtcatagtcg atatatttca aggcctcatc
     5641 gtccagcaaa aaaggtgaag ctagattaca ataataggaa accccctttt ctctgatcat
     5701 tgctattaca ttgaaccagt attttttatg aaaataaaca atcgctggtt cgcgcgttac
     5761 ccatcggcgt ccatcagatt cagtgactaa tgtgtgatca ttcacgccga tcatagagtg
     5821 ttcgcttgtt tttaatacca tggtatctcg ccacgttcga tgcaatttgc cgtcgtgctt
     5881 gtaactttgg atcgtcacaa actctccttc ttttggaact cccatagcaa cccttcctta
     5941 agcagcattt tgtgctttgt gtttgggtgt tcattacacc gacatcataa ttattatatc
     6001 aataaaaatg agctttgcct agaaaggatt cctattgttt cgatttttct ctaactgatc
     6061 taccagtttc atttggacct taggaaaaac gaccgaatca aatgcatcag gcttcaacca
     6121 cttcgaagtt ttgttctcgg taaattcttg ttctgctccc tcggttgccc gtccgtaaaa
     6181 aaggagaaca tgccatttca gatgactaaa aatatgagta acttctccta aatgtcgtgt
     6241 ctgccaaaca aagagttcct gcttttcaaa tgggagattt tgctcttctt ctgctactag
     6301 gtcatcaaac agatcgattt ctggctttgt ttcccattct tttttcaatc gctcatactc
     6361 ctcttgtgtc acttccatca ttggaaatgt ccacatattc gccagcaatt tttggctatc
     6421 tctttcttca aaataatacg ctccagaatg attttgaaga gctgcactga tataataaac
     6481 gtcttttggc tttgcttttt ttgtttttac aggaaaactc gtttggattc ctcgtttgtt
     6541 agctaaacaa aaggcttgga tcggacaagt ctcacacttt ggagaagttg gtgtacagat
     6601 agctgaacct agatccatca ttgcttggtt gaattcacct ggatgctttt catcaatgat
     6661 tttccgcatc gcttcatcaa agattttcct gctagaagct tttgcgatgt ctgcttcaat
     6721 gcaaaacaat ctgctgacta ctcgcatcac gttgccgtca actgcaggtt ctggaagtcc
     6781 aaatgcgata cttgcaatcg cgcctgtcgt atatggtcct attcccttca atgagctaat
     6841 ttcttcaggc gtttgcggca tttccccatc aaattctgac atgatctgtt tagcagcagc
     6901 ttggatgttc cgggctcttg agtaataacc aaggccctcc catgctttta aaagcttttc
     6961 ttctggagca tttgctagct cttcaattgt aggaaaccat tccatgaaac gataaaaata
     7021 atcgatcact gtgtctactc tggtttgctg aagcatgatc tcagagatcc agatacgata
     7081 aggatcacga ttatagcgcc aaggcaggtt tcttttttct tgttcatacc attgaatgaa
     7141 ctgatcttga aattcttttg tttctttatc tgtccatttt tcccattctt tattcacttt
     7201 cctcttcctt ttccgtaatg aatcgctgga tcatatccaa atcaaatcct ttttgatata
     7261 agctttgctt tacttttaga tttctttttt taggttcaaa ccttaaattt cttcgccata
     7321 gtttatctcc ttgtttgact aaataatcat attctatttc ttgatctgct tcttgcggaa
     7381 gatcagctat cgcttgttgg atcacttctt gagaaaagcc tttcgtcatc aatgtttgtt
     7441 ggatttttct caataattct ttttggcttt ttccgtgatt ttttccaaac gctttttcgg
     7501 ctgtctgatg tgcattttga acttggtctt caaatgtata ttggctgagc gcttgttcaa
     7561 tgatttcagg tttcaaacct ttttgctgca tctgctgcgc taatttcttt ggtcctttgt
     7621 cacttaagcg catattcgtg cgcacataac tttccccata gaccaaatca tcgacaaggt
     7681 ccaattcttt taagcgggct acgattttat ttcgatcttc ttgaaggatt tccttttctt
     7741 ttaagtatgt tcggatttct ttttccgatc gcaactgata acttaagtaa ttcattgcta
     7801 ggtgaaaacc gaaatcagct ccgctactct tcttgatctc ttggatagtt tcttcgtcta
     7861 attcccgtcc ttttaataat cgatagcgta ctaatacatc ttcagatact tgtaaagctt
     7921 ctccttcaga taaatctacg cgatagaaag ggcctttgcc tttactgatt ctcgtaacgg
     7981 ttaacataaa catcctcctc gaacatatat tctctatcat accacagaaa atccccgtaa
     8041 tcaggtatta tatgttagaa taaaccacag aaaaaagaaa aagggagata cttatggcag
     8101 aaacaattgt caaaactgga caaacggttc ctttgaaaat caagcgttta ggcataaatg
     8161 gtgaaggaat cggttatttc aaacggttga tcatatttgt tccatatgca ctaccaaaag
     8221 aagaagtact agtgaaaatc acgaaagcaa ctcctcgcta tgcagaagga gaattaataa
     8281 aagtcaaaaa aacaagcaaa gatcgcgtag tggcaccatg tcctgtttac tatgaatgcg
     8341 gtggctgtca attacaacac ttagcttatc aagctcaatt ggattttaaa aaggatctgc
     8401 ttttgcaagc attggaaaaa ttcaaaccag caggctttcg atcttatcaa cttttgccga
     8461 cgatcgggat ggatgagcct tggcattata gaaacaaagc acaatttcag ttacgaaaaa
     8521 ataagcagac tcaaaaaatt gaagctggtt tatacgaagc aaactctcat cagttagtcc
     8581 ctataacaga ctgcttggtt caagaacctc gaacacaaaa agtaatgaat actgttgttc
     8641 aactattgaa taaatttgat gcacccatct atgatgaacg gacaaacagt ggaatcttcc
     8701 gcacaatcat ggttagaatc ggtgttaaaa ctggggagtt acaagttgtt tttattactc
     8761 gcagtaaaaa attcccgcaa aaaaacgcaa tgatccgtga gatcaatgaa cgactgcccg
     8821 aagttgtttc aatcatgcaa aatgtccagg cacaaaaaac gtctctcgtg atgggggatg
     8881 aaacgatcca cttatgggga aaagaagcca ttgaagaaca aatcaatgaa gtgactttcg
     8941 atctttctcc tcgtgccttc tttcaactca atcctcagca gaccgaattg ctttatggcg
     9001 aaggaatcaa agcattagat gtccagccta atgaaacgat cgtggatgct tattgcggag
     9061 ttgggacgat cggcttaagt gtagcaaaac aagccaaaga agtacgggga atggataccg
     9121 ttcctcaagc aatcgctgat gcaaaaaaaa atgcggaaag attaggatat cacaacactc
     9181 gatatgaagt cgggacagca gagcaagttc tgcctaaatg gttgaatgaa ggttttcagc
     9241 ctgatggtat catcgtagat ccaccacgta cgggtttgga taacgcattg atccaatcat
     9301 tattgaaata ccctccaaaa aaacttgttt atatctcctg taatgtttct acacttgcca
     9361 gagatctggt taatttaagt aaaaagttca agattgaata tttacagtcc gtcgacatgt
     9421 ttcctcagac tgcacgttgt gaagttgtcg tgaagatgac gagactcgct gactaaatga
     9481 aagaggttgt gaaaaagtct gccctgtatc aagtaataag aacagccaaa caaaaatagc
     9541 tcttcatgtt ttatgaatac tgtacttgtg accgaagagt taacaggagg acactattta
     9601 tttaaaaaaa gggttgtgac atagtttttg tcacagccct ttttgattat tattggatat
     9661 tcacgtctat cacttgataa aatgcatttg tcgtatcgct gatattccat actgctaaaa
     9721 tcacattata tccttttcga tcctgcggaa gtgtgatcgt ttggttgact gtttttggtg
     9781 gaacagttgc tttgtcgtct atttttgtga tcaattcaaa atcactaaat ttcaaaggtt
     9841 gattaggatt ccaagttggt ttggtaatgt agtaatccca agtacttgtc cgatgttgtg
     9901 ctgttaaatt ccaagtaata tttaatgttc ctggattaac catgttttta tgccatctgt
     9961 tagatgtctg ttcatctaaa ggctcaaagc cgctgactcc tgcactagca atttttccat
    10021 caatgaatgt atttttggta gcttcgatac tttgcggttc ccattgtgct cttccgacat
    10081 tttgatttaa gtttcctgct gctgatgttc ctaggtatgc acggcttcct ggagaagtaa
    10141 tataaccatg cgcaaaacct ggaatgctaa aaccgaacaa ccctaaacta actaacccaa
    10201 taaacaataa cgtactaatc tttttcatgt agaaacctcc ttcatttgat aaccacattg
    10261 taaacgcttt attgtattaa cacaaacatt atgcttttat aattttatgt tgaagtaaaa
    10321 aaggtgaaaa aagtaagatg cagattataa cagaagtaga cgagaaaagt acaaatagaa
    10381 aacatgagaa tcaaatcata tgatcttttt caaaaacatc attcatataa acaaatgttc
    10441 aactttttaa taacaacaat tatcaatttt tttcttactt cacaaactaa atacaggtct
    10501 tgctgtgagc cttcatggta aactactatt atagaaagga gttagtaaaa tgaagatgat
    10561 aaaagatatt cgtttttggg tttgtgttat aggaattgtc atattaggct ttttatcagg
    10621 gttgcttagc ggaaatcccg gagaatatta ctattctttg caacttccac catttgcacc
    10681 acctagctgg atatttgggc cgatgtggac cttactgtat atattgatgg gtatttctct
    10741 ttatttgtta cttaatcaca acaacaaaaa acagcgaaac aatcttgtcg gtctttttgt
    10801 gattcagttc atttttaatt ttatatggtc tgctctattt tttaat
//
LOCUS       DAXLPC010000085        10665 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.086, whole genome shotgun sequence.
ACCESSION   DAXLPC010000085 DAXLPC010000000
VERSION     DAXLPC010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.086"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(183..1031)
                     /locus_tag="ACF3UE_002204"
     CDS             complement(183..1031)
                     /locus_tag="ACF3UE_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3635579.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1195..2097
                     /gene="gnd"
                     /locus_tag="ACF3UE_002205"
     CDS             1195..2097
                     /gene="gnd"
                     /locus_tag="ACF3UE_002205"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HFD3635580.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            2099..3100
                     /locus_tag="ACF3UE_002206"
     CDS             2099..3100
                     /locus_tag="ACF3UE_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HFD3635581.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            3097..3381
                     /locus_tag="ACF3UE_002207"
     CDS             3097..3381
                     /locus_tag="ACF3UE_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFD3635582.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            3414..4211
                     /locus_tag="ACF3UE_002208"
     CDS             3414..4211
                     /locus_tag="ACF3UE_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFD3635583.1"
                     /translation="MGYSTNLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            4225..5058
                     /locus_tag="ACF3UE_002209"
     CDS             4225..5058
                     /locus_tag="ACF3UE_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3635584.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            5076..5933
                     /locus_tag="ACF3UE_002210"
     CDS             5076..5933
                     /locus_tag="ACF3UE_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3635585.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            5955..6464
                     /locus_tag="ACF3UE_002211"
     CDS             5955..6464
                     /locus_tag="ACF3UE_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFD3635586.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            6501..6902
                     /locus_tag="ACF3UE_002212"
     CDS             6501..6902
                     /locus_tag="ACF3UE_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635587.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            7014..7367
                     /locus_tag="ACF3UE_002213"
     CDS             7014..7367
                     /locus_tag="ACF3UE_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635588.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            7401..7844
                     /locus_tag="ACF3UE_002214"
     CDS             7401..7844
                     /locus_tag="ACF3UE_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3635589.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            7861..8946
                     /gene="uxuA"
                     /locus_tag="ACF3UE_002215"
     CDS             7861..8946
                     /gene="uxuA"
                     /locus_tag="ACF3UE_002215"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFD3635590.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            8939..9652
                     /locus_tag="ACF3UE_002216"
     CDS             8939..9652
                     /locus_tag="ACF3UE_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3635591.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(9859..10008)
                     /locus_tag="ACF3UE_002217"
     CDS             complement(9859..10008)
                     /locus_tag="ACF3UE_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635592.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            10404..10604
                     /locus_tag="ACF3UE_002218"
     CDS             10404..10604
                     /locus_tag="ACF3UE_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3635593.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         3559 a         1690 c         2314 g         3102 t
ORIGIN      
        1 cgcatctaac aagtaactcg aataatacca atacaacctt ctccaaagat gcgatgacat
       61 acgttctaac ccaccgacta ttgatgttct gtaccaccct tgcagaacca aaaaagccac
      121 taccaaatat ttggtagtgg ctttttttgt tttatggatt tttcgctttt tctgttatgg
      181 tgctattctt tgatttcaga aatagtatgt cgaactttag cgatagaacg acgtgattct
      241 ttttcgttgt aaaacatcaa aatcacatat agagagtcca aaatgcttag ttgagaaata
      301 cgggaagcta aagcttcaga tcggaattct gtttcttcag aaatagaaat aaaaacgaca
      361 tcgccaagtt tagcaaggga agaattagct tggctagtaa taacgattgt ttttgctcca
      421 gtttttctta cggtttcagc aatatggatt gtttcttttg attgccctgt gtgagaaatc
      481 aaaacagcac agtctttttc cgtcaataaa gaagcttcca tcaattgaat atggtaatcc
      541 gtgctgtgag aagttgcgat aggggaacgc aaaaatttat gataagcgtc agttgctaca
      601 atctctgaac cgccaacacc gaaaaaatag acacgtttag attcattgat aatagtagcc
      661 gcttttttta gatccttttg ttgtaacaac ttttttgtgt catttaaagt tgaaatacta
      721 gactcgaaca ccttttgcgc catagtgagc tcagtatctg ttttctgaat attttcgtgg
      781 atagaaatag cagatagatc attttcttgg atcaacatgg ccattttaaa atctttaaat
      841 ccattataac caagtttttt tgtaaattga aaaaaagtag agtcagcaat gcccagttca
      901 cttgctaaat tgctaatagg actatgactt actttgcttg gattttctaa aatataatcg
      961 gcgatagcct gttcttttgg gctgaagtcg ttgtacattg ttttgatttg tagtcttatg
     1021 gagacgctca tgagaattcc tcattttcat aataagatta tcattttttc cgttctcatt
     1081 aatgttaaag atacaaggag agtaggaaaa aatcaaacaa aaaatatttt tgtaaaatct
     1141 atttacaaaa aaattttttt gtataatgag ggtataagaa atggaggcgc tatcatggaa
     1201 attggtgtaa ttggtttggg aaaaatggga ttgaatttag ctttaaactt aaaagagcac
     1261 catcacaaag tacaaggact cgacatttca agtacagctg ttagtcaggc aagagaaaat
     1321 gacattcctg cttatcaaga gatctctgaa tttctagcta cttttgagca gaaaaaaatc
     1381 atctggttaa tgcttcctgc tggagagata accgaaaaca tgttaagaaa actttttcca
     1441 aaactcggac caggagacat tattattgaa ggcggaaact cttattataa agattcaatc
     1501 cgtcgagcag aagagtttca gaaaaatgaa atcggttact tggattgtgg gacttctgga
     1561 ggaatcgaag gagcacgaca tcaagcctgc ttaatgattg gaggagataa agaaactttt
     1621 ctatccgtgg aacaattatt caaagatgta gcaattgaaa gaggatatct gtatgctggt
     1681 gcatccggaa gcggacactt cttgaaaatg atccataatg gaatcgaata tggaatgatg
     1741 caagcaatcg gtgaaggatt ccaacttgta caaaaaagtg agtatgcttt tgacttggaa
     1801 caagtcgcac gtgtttggaa tcatggttcg gtgattcgcg gctggctgat ggaaatcatg
     1861 gaagatcagt taaacgaaca tcccaattta agtaattatc ggggaatcgt ttctgcatca
     1921 ggtgaagcaa aatggacggt tgaaacagcg ctagaaatgg ctgttccagt tccagtaatt
     1981 gcaactagtt tgttcatgag gaatctttca caggaagaag atagtttttc agcaaaagta
     2041 gtttcagcac taagaaatgg gtttggcgga catgaaatag ttgaaaaggg tgagtaaaat
     2101 gccagattat catatagcaa tcgttaattc cagcagtttc ggaagagtct ttccacacca
     2161 cttggaaaga ttaaagtcag ttggagacgt tcatttcttt actgttgatc aagagattcc
     2221 aggaaaagaa ctagcggagt tacttaaagg attcaatatc attattgcaa gtgttacgcc
     2281 attttttcga cgagattttt ttgaaaacaa agatgaactg ctattgattt cccgacatgg
     2341 tattggttac aacaatattg atttaaaagc agcaaaagaa caccagacaa tcgtatctat
     2401 catacctgct ttagttgaac gaaatgctgt agcagaaaat aatataacta atttgttgtc
     2461 catgcttcga cgcacgacac aagcacaagc aagagtcaag gacgatcgat gggaagatcg
     2521 ggcggagttc gtcggtagga cgctgtttaa caaaacagtt ggtgtgattg gtgcaggaaa
     2581 taccggaagc ggagtaatcg aaattttgcg taacggtttt cgctgtgatg ttctagctta
     2641 tgatccttac aaatcagatt tatacatcga aagctttggt gcaaaaaaag tagaacttca
     2701 agaattactg gaacaatcag atatcatttg tttatgtgcg aatttgacag aagagaacta
     2761 tcacatgatt tctgataaag aagtcgatca gatgaaagaa aatgtttatc tatctaatag
     2821 tgcaagaggc gctctagttg atgaagaagc gatgattaat ggtctgaaaa gcggaaagat
     2881 cgcaggatat gccacagatg ttttagaaga agaaccggga cgtcaagatc atccgtattt
     2941 agcgtttgaa caagtagtga ttacgccaca tatatcggcc tacacaaggg aatgtttaga
     3001 agcaatgggt gaaaaatgtg tcagagatgt cgaacagatc agtcagcacc ttcttcctga
     3061 acgttctgtc cagacaaaga gcaactatat aaaaggatga tgaagaaaat ggtgaacggt
     3121 ttaaaagtga aaacaggccc tcaattttat ttatatgaag aaggtggtat ttcaaaagtt
     3181 tctgatctct tgaaatcata cggcgcgaaa agagtactgg tcacccacgg aacggtatca
     3241 tgggaaaagg cgctacctaa attagtattt ttgaatgacg aaacgattca atttttttat
     3301 catcgttatt ctggagaatg tagttatgct gaagccagac gaatagctac aatcatcaaa
     3361 aaaatgaaat cgatttcgta gttggcgttg gcggaggaaa actgaccgat ctagtgggtt
     3421 atagtaccaa tcttgcaaga atcgatttcg gagtcatccc tactttagct agtaattgtg
     3481 ctccatggac acctcttgct gtcatgtata aggagaatgg acaagcagaa gggaaaacag
     3541 aacactttta cagacaagct gcttttttta taacagatcc ccaattagtg attgattccc
     3601 ctgttccata tttcattgcc gggttagcag atacactagc aaaatggtat gaatctgagc
     3661 tcatcttaga acaagatttt ttgcaagatg aatcattttt gaagctagca caagatactg
     3721 cgaagatctg caaagaagag attttgaatc attctgctaa agcaatccaa gatatggcac
     3781 aaagaaaact gacatcggag ttcaaacagc tttcagagat tatctttgct gttgctggtt
     3841 tagttggagg attaggagat aaatacgcaa gaaatgcggc agcacatgct atgcatgacg
     3901 ctatcagtaa atatattccg gaaagccatc gttttctaca tggagaaaaa gtagcgtatg
     3961 ggattttcta tcaactggca ctagaaggtc gctgggaaaa aatagacgag ttatatcctt
     4021 tgtatcggga attagaactg ccggtttctc tagaacaaat gggattattt ccgaaagata
     4081 aacagataat agataaaatg gctgaattta ttgattcgaa agagaaagtg catttgattc
     4141 ctatagaggt aacacagaaa tcactgatac agtcaatgat ggaactggaa ggttatatca
     4201 gaaagatctg aaggaggagg acacatggaa acattaagtg tagtacaaag tttgttgatt
     4261 gctttatggg tagccgcggt tatgtcccgc tggttaggtg gaggagccac gttgacctta
     4321 cgtttttctc ctttgatgac tggattagtc gtcgggttga tcatggggga agttgcacaa
     4381 gcgatgattg ttacagccgc tttgcaaatg atttatatgg gggttttttc tccaggagga
     4441 tcaatgccag ctgaaccatc tattgcagca gctatcgcag taccagtcgc attattaggg
     4501 gatctgtcgc cagaagcagc gattgccgtt gcggtgccag tcggattgct cggaagttac
     4561 ttgtatcagt ttcgtttttt catcaatact tttttaggta aatatacaga caaagctgta
     4621 gaagatttga atacaaaagc tatggcccga tcaattattc tttatccaac ggttgcctca
     4681 tttttattat tcgttccgct tgttttcatt gctttatatt taggggcgcc attgatcgct
     4741 gatgtaatca aagctttaga gggaacagtc gttatccaca ttcttgaagt agtaggtgga
     4801 gggttagcgg caatcggtat cgcgacaact gtatacgtta tcggtcgaaa agattatctg
     4861 gtctttttct tccttgctta ttttatgagt gttgttttga aatctttaga tattacgatg
     4921 gttacttatg ccatttttgg gattattatc gctttgatct ttgtccagtc gcaaaaaggg
     4981 aaacaagtac agcctgccac aagcaataac aattcagcat cttttgatga cgaagatgac
     5041 tatgatgacg gattttaatt taggaggaat gggaaatggc tgaaataatg gataatcaaa
     5101 caggtgctcc tgaagaaatc acgaaaaaag atgtaacaaa agcctatctg agatggcatt
     5161 ttgcaaacga aattcctcac tcttttgaac gttacttggc gccatcacta ctatacggaa
     5221 tgatgccaat cttgaaaaaa ctttataaag atgaagactc tttaaaagca gcatataaac
     5281 ggcagttact gttcttcaac actcaattaa gctggggtgg cggtgtgatt actggcctaa
     5341 tgtcttctat ggaacagcaa agagcagaag aagagtatga agaaaaagag atcttgatgc
     5401 aggatgactt gatgtataac acgaaagcgg gattgatggg ggcactagca ggaatcggag
     5461 atgcaatcga ttcaggaacc gtccaatata tttttatcgc aatcgcggta ccttgggcac
     5521 aacagggaag tcctttaggc gcactttttc cttttatctg ctttgggttg tatcaggttt
     5581 tactaggggt atttttcgca agacaagctt tcactatggg ccgtaatgct acaggcctaa
     5641 tgcaaaacac tggtgttcag acagcgattg aaatgctatc agttttaggg ttgtttatga
     5701 tgggggtgct tgcgggaaac tatgtaaaag tagaatcttc attgaaattt gcgatatccg
     5761 gacgtgagtt tgttatccag gaaattcttg atcaaatcgt gccagggata ttacctttag
     5821 ctgtcgtaat gggtgtgtac ttgttctata cgaaaaaagg attgaaagtc acacaagcat
     5881 tattatggct gactggaata ttaattgtgc tagcaggaat cggtatttta taaaaagaag
     5941 ggaacgtgaa taagatgggt gtagtcaatt tagcgcgtgt ggatgagcgt ttgatccatg
     6001 ggcaagtaat ggtaacgtta tctcaaaaaa gtggagtgaa ttccattttt gttgtagacg
     6061 aagttgtagc aaaagataaa tttatgagag atctttacaa aaatgcagga agccgtacag
     6121 gacaaaaaac aattgtcatt acaccagaga aagctaaatt ctattgggat gaatatcaat
     6181 ttaaagaata caattgtatt ttgatcgcaa aaacagtcca aacgatttac gacttagtaa
     6241 aacacggaat ccccatggaa gaattgaata ttggagggat tgctcaaaaa aatcctgata
     6301 cagatctttt agtgacgaaa tctgtttatt taaataaatc agatgctgaa aaattgaaag
     6361 aaatgaatga acaatatggc gtaaagaata tttattttca agccactcca tctgcaccta
     6421 aaacaggatt aaaagatgta ttgaacaagt ttgatttgtc ataaacaaat gcttagaaaa
     6481 aagataaaga gggcgaaaaa atgaagaaga acgagctgtt tcgtgattgg gaatttcgtt
     6541 atcgctatat ttaccgtaag cgccgtacaa aaaagagtaa acagcgtttt ctttcagcat
     6601 tagtatcaga tatttacagt atgagaacag atgtgacagt cattgcttac gatacgctag
     6661 cctaccgatc aaaaaatatt tatgttggag atatcgaaaa agcagagaaa gttatctgta
     6721 cttattacga tacacccgtt catgcattag gaagttattt catgtttgat tggaaagacc
     6781 aaaggaaaaa aacaatctac tctatattat tgtccttcat tttgttgttc agtttaggtt
     6841 ggtggggaat gatgatatat aacaaaaatc ctcatcacgt attcgatctg ctatccgtat
     6901 aaacaggtat cactgtacta gcatttggga gctacttttt cttattggga aaagcagctc
     6961 gcggatggcc tagcagacaa acttttattc gaaatacttc atccatatta acgatgctag
     7021 aaatgatccg tacgattgat gatccgagtg tagcgtatgc gtttgttgat gaaggctgtt
     7081 atggagaaaa gggcttagac agcgtgagat cgggtatgaa aaaagaggct attctttttt
     7141 atctagactc tgttggggca gatacaccgc tacagttttc gggaaattat ttttcaaata
     7201 aagaacagtg gctgaaacaa gttgataagt tgaaagaaaa aaacgtcaat tatattttta
     7261 gtgcaagaaa aaagcaagcg cagttcttct atttgaccaa aacagattta cgagggaaaa
     7321 catttaattg gcaaaatgcc aatcagatta ttgctctttt tcgataagta aaaagtgcaa
     7381 aacaaggagt gagaagacta atgttggaaa tcatgatcgt tacacatggt aagttgagcg
     7441 aaggactgaa agatgcggcg gaagtaattg tcgggacatc gagccatatt gaaacaatgt
     7501 gcttagagtc tggggaggac atccaaacat tcggagagaa ggtcaaagaa aaattaacta
     7561 tgatcaacac agcagaaccc atgctagtat ttgttgatct aattagcgca agtccgtaca
     7621 atcaagcgct cttggcagtc aatgaactga ctgaagaaaa gaaagcagcc acttatgtca
     7681 tagggggcgt gaatctgcca atgttgttag aagcaatcaa tcatcagatg cttcacacac
     7741 cgatagaaga agcggtggaa caaattgtca aacaaggaaa agataattta actgtttggc
     7801 atgcttcagc ggaagaaaaa aaattagatg aggacgattt ttagaaggaa ggctgaaaag
     7861 atgaagtggg gatttagatg gtatggtgaa aaaggggatt cgatcccatt aaaatatgtt
     7921 cgccaaatac cgggaataaa tgggataatt ggaactttgc tgactaaaat gcctggagat
     7981 gtttgggaga tttcagaaat tgaggagttg aaagcatctg ttgagagcca aggactggaa
     8041 ctgcttggaa ttgaaagtgt agcgatccac gatgcaatca aggcagggac agatgaacga
     8101 gattactata ttgataacta tatacgaaca atcaaaaact tgtctcgatg tggggttcga
     8161 ttgatttgtt atagcttcaa accaattttt ggatgggcga aaactgattt gtttaatgaa
     8221 aacaacgatg gaagctattc tcttttatac gatcagaaaa tcgtcgatca gatggagcca
     8281 ggagaaatgt atcaattgat acacagccag tcaaagggat tcaaattgcc gggttgggaa
     8341 gaagaacggt tgaaaaaatt cgctcagctg gaaaaactgt atgaaggaat gaccgaagaa
     8401 gaattatttg aaaatctgac ttatttttta gaaaaagtga ttccagtgtg cgaaaaagca
     8461 gatgtaaaaa tggctatcca tccagatgat ccgccatggg aactttttgg ttttcctaga
     8521 gtgacgaaaa atcttggcga cttgaagaaa attctaaatg cagtagattc tccatataat
     8581 ggactaacgc tgtgcacagg atctttaggg gcaaatccgg aaaacgattt agttgaaatc
     8641 atccatgagg taggttcgcg catccatttt gtccacttca gaaacgtgga gtttttagga
     8701 gaaagaaagt tcaaagaaac ggcacatccc tctacagaag gctcccttga tatgtatcat
     8761 attatgaaag cgttggtgca agaagggttc gacggtccta tacgccctga tcatggtaga
     8821 accgtgtggg gtgaagtggc tatgcctgga tatggcctgt atgatcgtgc aatgggactc
     8881 acttacatgc aaggtctata tgaggcgata agtaaggaaa aaccactggg agagcattat
     8941 gaataaaatc aagctcttca tctttgatat ggatggcctt ttattagaaa ctggacgttt
     9001 agcttatcgt gcttatgtaa aatcagcaca aaagtatgat tatgaaatgc gtaaggaagt
     9061 ctattattta ctaactggcc aaacagaaat ggcgataaga gaacaaatgg gcattttgta
     9121 cggagaagat gttccatata tcaaatggcg agaagcaatc aatcaatata aagaaaaaat
     9181 cgtgaaagaa gataagagag tatatacgaa aaaaggagca gaagaaattt tatcttttgc
     9241 aaaagaaaga ggaatccata caatcgtggc ttcgtctaat acacgggtaa aagtagaaat
     9301 gtatttaaaa atggaaaatc tatatgcctt gtttgatcaa atcatttcag gggatgatgt
     9361 aaaaaaagga aagccggaac cagagatctt tttgaaagct tgttcaaaaa tgaatattcc
     9421 tccaagtgaa gcacttgtat ttgaagactc gattgcaggg atcgaagcag caaggcgagc
     9481 gggcattttg tcttttctca tcaaagatca tttgataggg ttgcccgatc ataatgggaa
     9541 gcataagttg aaagtagatg taagtttata tgaatccaat aaagcagact atgaatttta
     9601 tgacctgcat caagcaaaac gatttttaga aagtaaaggg ttgtatctct aataaagagg
     9661 actattttct agtcctcttt atttattgtc ctgcacgact gagggaacag atgaaaaaga
     9721 agtaattttt tattttgaag tatctacctt atttgtagtg aacaatttag aacaaacaca
     9781 aaacgcatct actgttatct accagtagat gcgtttaaag agaagaacga gaatcgtcca
     9841 tatgagggtt tccactcctt atgcagattt ttttaattct tgcactgctt gttcgatcgt
     9901 aacacctgtc gctacatgat tggtattttc tttgtcaaaa acgacaaata gattcaaatc
     9961 tgtatccaag gttactcgat attgtatatc tttgttatag aatgtcatag ccattctcct
    10021 ttctttaaat acttgctgaa aggcaacgaa cgcgttgata acgaaattcc atttataagt
    10081 ataccaccaa ttgaaaggtt ttcatagtta agaaatttta aagtcaaaag ttgcagataa
    10141 aagcaaataa acaagaaaac aaaaagtgaa tcaatcgcgg ttattcaact ttttcttcga
    10201 ttcgaagaca atagaagaca atgaatttta tatttcattg cattatcctt gtgttattag
    10261 aaaaagcatg atatattaaa tgagtaatct attttgaaac gtaatttgag cgatatatct
    10321 acatagataa aactcctttt gcctatcaaa tatttattgc aacgaaaaaa cgtacattga
    10381 tacgtatcag gaggaattta tttatgaata acggtacagt aaaatggttc aacgcagaca
    10441 aaggttttgg ctttatcact ggtgaagatg gaaatgatgt atttgcacat ttttcagcta
    10501 tccaaggtga cggcttcaaa actttagaag aaggccaagc agtgtcttac gatgttgaag
    10561 atggtcaacg tggccctcaa gcaacaaaca ttgttaaagc ttaataaaaa ttgactttta
    10621 accgtctttt cgaaagaaaa gacggttttt ttgtacgaaa aaatt
//
LOCUS       DAXLPC010000086        10584 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.087, whole genome shotgun sequence.
ACCESSION   DAXLPC010000086 DAXLPC010000000
VERSION     DAXLPC010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.087"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(138..623)
                     /locus_tag="ACF3UE_002219"
     CDS             complement(138..623)
                     /locus_tag="ACF3UE_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFD3635594.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    713..1058
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1103..1744
                     /locus_tag="ACF3UE_002220"
     CDS             1103..1744
                     /locus_tag="ACF3UE_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFD3635595.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            1763..2398
                     /locus_tag="ACF3UE_002221"
     CDS             1763..2398
                     /locus_tag="ACF3UE_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFD3635596.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2416..3231
                     /locus_tag="ACF3UE_002222"
     CDS             2416..3231
                     /locus_tag="ACF3UE_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3635597.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3550..4986
                     /locus_tag="ACF3UE_002223"
     CDS             3550..4986
                     /locus_tag="ACF3UE_002223"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3635598.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5175..7622
                     /locus_tag="ACF3UE_002224"
     CDS             5175..7622
                     /locus_tag="ACF3UE_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFD3635599.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            7852..8919
                     /gene="rlmN"
                     /locus_tag="ACF3UE_002225"
     CDS             7852..8919
                     /gene="rlmN"
                     /locus_tag="ACF3UE_002225"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFD3635600.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            8909..9115
                     /locus_tag="ACF3UE_002226"
     CDS             8909..9115
                     /locus_tag="ACF3UE_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635601.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(9112..10215)
                     /locus_tag="ACF3UE_002227"
     CDS             complement(9112..10215)
                     /locus_tag="ACF3UE_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFD3635602.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
BASE COUNT         3496 a         1809 c         2289 g         2990 t
ORIGIN      
        1 ggaagaatac tcgtattagt tttcagcgtt catactagtt gttacattgt ttgattggcc
       61 aaaagaattt ctgatatatt ttgtgctaaa taaagaaaaa gacgcttgaa ttgggaaata
      121 agaaaactac tctatcatta caaattttca taaactggca gatgttctaa gtaaacaagt
      181 atcttttcaa agtcggaaaa atccataatc aacgtagtgg tattgatatt tggatgaaag
      241 cctacggtat cttgacgatc aatagcagca tcgatcacga cttggatttt tttctctttg
      301 tcgtgcatca atgctaatgg agtcactgta cctgctggaa cgcctaggag gtcaggaagc
      361 tgttcttcag aaacaaaaga taagcgcttt tcttttaatt gttcagctag ttgttttaaa
      421 tcggcgtgct tttcatcagg caagatgaca agatagattt gttttccttt tcttgatttc
      481 aataatagat tttttacttg cggaccaggt agggaaaaag ggacattttt gactgacgta
      541 atcgcaggat gatcgacttt ttgaaaagag atacccagtt tttttagtag ttcataagct
      601 tcttgttcgg ttgcacgact catcgcgcat caccctcctt tttttattag tgtatcataa
      661 aaaagagttg acaaatgaaa aataatcatg taaattacac gtaaagttaa aacaaatgac
      721 atcgaaaaga agagtagccg ttaggtgttt ttagagagtc tctggttggt ggaaagaggc
      781 agcagttaac cgtgaaacac atcttggagt cgattttctg aagcgtatag taggaaaatc
      841 cggggagccc gttacagctg cggtcgttgc tagatgacca gataaggctg gcttttccgt
      901 gaggagtcgg taaaaaaagg tggaaccacg tgattaacgt cctttgatct tcggatcaaa
      961 ggactttttg ttttcatctg aacggcaacg actgtgtgag gttttttctg caaggaaaaa
     1021 ataaacagag gtggaaccac gtataatacg tcctcttggc atttgccaag aggatttttt
     1081 tattttaaag gaggaaaaga agatggagta tttgattgaa gttatgccgc aattattagt
     1141 aggagcactc acaacattga aattattttt atttaccttg attggctcat taccattagg
     1201 gattgtttta gcattaggat tgtctttgca ttttaagccg ctacgctact tgcttcaaac
     1261 atatgtatgg gttatgcggg gaacaccgct gttgttgcaa ctgattttta ttttttatgg
     1321 gttgccgacg attgggatcg tttttgatcg tttcgaagca gcactcattg cctttatctt
     1381 aaactatgca gcttattttg cagagatctt tcgtggaggg atacaatcga ttcctcaagg
     1441 tcaatatgaa gcagcgcaag ttttgcaatt aagtcccttt caaacggtga cgaaaatcgt
     1501 catcccacaa gtgacaaaga ttgttttacc ttctgtaggg aatgaagtta tcaacttggt
     1561 caaagattct tccttgatct atatattagg tttaggtgac gtaatgcgtg ctgggaaaat
     1621 cgcgatggaa cgcgacgcga ctttactgcc tttgctaggc gtggcaatca tctatcttac
     1681 attgactggt attctaacaa tcataatgaa acaagttgaa ggaaaattaa attattaccg
     1741 ctaactgata ggaggaagaa atatgattga attgaagaaa gtgaacaaag catttggtga
     1801 aaaaaaaata atcaaagatt tgaatctaat cattccagat gggaaaacat tagctatcgt
     1861 aggtccttcc ggtggcggta aaaccacgct tttacgtatc ttggctggct tagaaagttc
     1921 tgacagcgga gaattttatt tagacggtgt accgttcaac ccattcgagc ttaaaatgaa
     1981 agaacaagtt gtaggagtcg tattccaaga cttccagcta tttccacatc tgaatatttt
     2041 tgaaaacatt accttagcac caaaaatggt attgaaacag acaaaagaag aatacaccaa
     2101 aaaagcagaa gaattagcgg cttcattagg gattagtgat ttattgaata tctatcctta
     2161 tcagctttct ggcggacaaa aacagcgggt agcgattgcc agagcattgg ctatgaatcc
     2221 acgggtattg gcttatgatg aaccaacaag tgctttagat cctgaattac gccagcaagt
     2281 cgagcgtttg atcctatcat tgaaagaaga tggggtaacc caaattattg tcacccatga
     2341 tttagtattt gcagaaaatg tcggtgatca attactaaaa gtttccccaa ttcattaaga
     2401 aaggagaaga tagagatgaa aaaaaccagt tttctattcg ctttgatcgc aggtcttctt
     2461 ctttttgcag gctgttcgaa caaaaaaact tcagcagata attgggcgac tatcaacgaa
     2521 gagaaaaaaa tcgttatagg tttagacgat acatttgttc ctatgggatt tagagataaa
     2581 gacgggaagc tcacaggatt tgatattgat ttagccaaag cagtctttga acaatatggg
     2641 attacggtag actttcagcc cattgactgg tcaatgaagg aatttgaact gaacaatgga
     2701 acgatcgatt tgatatggaa cggctattcc aaaacgccgg caagagaaaa gaaagtgcaa
     2761 tttacaaaac cttatatgga aaacgatcaa gtgctgatca cacctaaaga atcaggaatc
     2821 acaaactttg gacaaatgaa taataagaga ttaggtgcgc aaaatgggtc atctggttat
     2881 gatgtattta cgaaacaacc agaagtatta aaagagatag tcaaaaacca agatgctgtt
     2941 ttgtatgata gttttaatga agcattgatc gatctgaaaa gcagacgggt cgatggtctg
     3001 ctgatggata aagtatacgc agactattat ttgaaacaaa gaaacgaact agaagacttc
     3061 aacataacaa aaggttctta tgagagtgag gattttgcag ttggtgcacg caagtcagat
     3121 agtacattag tgaaaaaaat caatgaagcc ctagatcaac tagagaaaac aggtgaattc
     3181 caaaaaatat ccgataaatg gtttggcgaa gatgttacgc cgagaaatta acaaataggg
     3241 gactgtgaca aaagacgtgt cacagtccct ttttccgaat aaacagtgtt ctcctgccaa
     3301 ctccttgtga ctcggagctg aatggcaggc tcacaacctc ttggtaaacg gtgttcaaaa
     3361 gccagttttt cggtattaag ccaaatttat gcaaaaatgt agaaagccat tttcacaaaa
     3421 tttttcttac tactcgaaac taagcgactt tttcacaacc tcctttacat aattttattt
     3481 tgttgtggaa ggggtttcgt gttattctaa aagaggaacg attgaaggtt ataggaaagg
     3541 aagagatgaa tggaacacaa agaacttacc tcatttccaa aagattttct gtggggctct
     3601 gcttctgcag cgtatcaagt agaaggagct tggcaagaag atgggaaagg agaatcagtc
     3661 tgggatcgat ttgtacggat acctggaaag acatttaaag gaacgaacgg tgatttggca
     3721 gtagaccact atcatcgtta taaagaagat attgctttaa tgaaagaaca aggtctgaaa
     3781 gcttaccgct tctctgtagc ttggacacgg atttttccta atggacgagg agaagtcaat
     3841 caagctgggc tcgcttttta tgagagattg atcgacgaat tgattgaaaa cgatattgaa
     3901 cctatgttga ctttatatca ttgggatctt ccacaagcat tgcaagatga atataatggt
     3961 tgggaatcac gtcagatcat tgaagatttc actcattatg cagaaacatt atttgaggca
     4021 ttccgcggga aagtccatta ctggattagt ttgaatgaac aaaatatctt cacttcatta
     4081 ggttatttgt tagcagcaca tccgccaggt gtgacagacc cgaaacgaat gtatgaagtt
     4141 aaccatattg ctaatttagc aaatgcatct gtcatcaata aatttcacga gttagaaatg
     4201 cctggaaaaa tcggaccaag ctttgcgtat acgccaaatt atccaattga cagtaatcct
     4261 gaaaatgttc tggctgctga aaatgcagaa gacctgatgg ccaattattg gatggatgtc
     4321 tatatgtggg gaaaatatcc gattgctgcc atgaggttct tagaagaaaa aggatgggca
     4381 ccaacgattg aagctggcga tgcagaattg ctagaatctg ctaaaccaga ttttcttggg
     4441 atcaattact atcaaacggc gacgaatgca ttcaatccat taaacggagt tggtgctgga
     4501 aaaatgaata cgacaggaaa aaaaggttca tcagaagaaa ctggagttcc tggaatgtat
     4561 aaaaaagttg agaatccatt tgtcgaacga acaaattggg actgggagat tgacccagaa
     4621 ggattaagga tcggactgcg tcgtatcaca agccgttacc gcatgccggt actgattacg
     4681 gaaaatggct taggagagta tgacaagttg acagaagata aacaaatcca tgacgactat
     4741 cgaatcaatt acttacaaag ccacgtcaaa gccatcaaag aagcaatttc ggatggagca
     4801 gaagtcctag gctattgcac ctggtcttat acagatttgc ttagctggct gaacggttat
     4861 caaaagcgat atggatttgt atatgttgat caagacgaaa cacaagaagg atctttggaa
     4921 cgatataaga aagacagtta ttactggtac caaaaactga ttgaagaaaa tggagagaac
     4981 ctttagttca catacttaaa acaagaaggt acggctggat atggccgtgc cttttcttga
     5041 taaaatcatt tagaaattaa gaaaaactgt aaaataagct gaaaaatgaa agaaagcgtc
     5101 agttctttca aacaaaactt tagttccctt actttttttt gtataatgaa acttgatgaa
     5161 atgagggata ataaatggca caaaagaaac ggcctactaa aaaaaggaaa aagacgaaaa
     5221 aaacgaaaaa gcaaaaacag cagcaggaac aaatgctgac gattggtgtt gggtttgcct
     5281 tgattttatt tgctgtcttc ggctttttaa aattaggttt tttaggaata ttgattgcaa
     5341 acggctttcg gatcattgca ggaaatactt accaaatcct ctgtctttta ttagccgtat
     5401 taggattttg gattgtcatt aagaatacag agttttcaat tggtaaaaac cgacgctggt
     5461 ttggcggcat actcttttat ttcggtatct tattattgtt acatgcccat ttatttggca
     5521 aactccatac tggggaacca aatatcatgg ggacgacatg ggatttgtta gccagtgata
     5581 taaaacaaag tcaagtagac aataacgttg gtggtgggat gattggagca atcctttatc
     5641 attttactta cttcttgatt gcacagcctg gaagttattt agcagcagtg ctattactgg
     5701 caggaggagc attcctgttc agtaatctgg aaggctatca gctgttaaat ggtatccaat
     5761 caattggaga acgagtacag gaattattgg aaggtgatcc tgccaagcaa gctcgaaagc
     5821 aagcggcaaa ggaagagaga atgaaacagc gcgcagaagc gaaagaagca aggcgcttag
     5881 ctgcaaaaga agctgcagaa aaagaagctg cagaatatga gaagaaaaaa gcggtgagcc
     5941 agcaaaggga aaatactgct gatgaatggc aggaaccaga aaatacagag ccggagcagc
     6001 taagttttgt tccaatcgac agttttcaag aaaatatcca tcctgcgaat ctagagaaac
     6061 cagtaccaga tacaccaaaa cagaccaata cagcagaagg tttttcagat gagttgccag
     6121 aggatgacgg tacctcatta gaatttgaga ttgaagcaga acaggaaaat caagactatg
     6181 aattaccgac agttgatttg cttgattcta taccaactgt ggatcaaagt gatgagtata
     6241 aaaaaattga aaaaaatatc ggcgtattag aacaaacttt ccaaagtttc ggtgtcgatg
     6301 ccaaggtcgt caaagccagc ttaggaccat ccgtcacaaa attcgaagtc cagccggctg
     6361 taggggtaaa agtaagtaaa attgtgaact taacagatga tatcgcgctt gctttagcgg
     6421 cgaaagatgt ccggatggaa gcaccgattc caggtaaatc actgattggt attgaagtac
     6481 caaatggaaa gatcagtatg gtttccttta gagaaatcat cgaagcacaa ccaaaccacc
     6541 cagataaatt actagaagta cctttaggac gtgatgtttc tggacgggta caaacggctg
     6601 atctttcgaa gatgcctcac ttactcgtgg ctggttcgac tggtagtggg aagtcagtag
     6661 caattaatgg gattatcaca agtatattaa tgcgtgctaa gccccatgaa gtaaaactga
     6721 tgatgatcga tccgaaaatg gttgaattga atatgtacaa cggcatacct catctgttga
     6781 cgccggtcgt gacgaaccct agaaaagcag cgcaagcctt acaaaaagta gtacaagaaa
     6841 tggaagaacg atatgaaaaa ttcgcggcaa ccggagtaag aaatatttct ggttacaatg
     6901 aatttgttca acagaaaaac ttggaaaacg gaacgaaaca tccaacctta ccattcatcg
     6961 tagtgatcgt agatgaatta gctgatttga tgatggtagc cagcaatgaa gttgaagatg
     7021 cgattattcg tttagcgcaa atggctcggg cagcggggat tcatatgatc ctagctactc
     7081 aacgtccaag tgtggatgtt atcacaggaa tcatcaaagc aaatgtacct tccagaatgg
     7141 catttgcggt atcaagcggt acagattctc ggacgatcat tgattctaat ggggcagaaa
     7201 agctcttagg gcgaggagat atgctattct tgccaatggg tgagaataaa ccgatccgtg
     7261 tgcaaggagc attcatttct gaccacgaag tagaacgggt cgttcaattt gttacagatc
     7321 agcaagaagc tcattatgaa gagaaaatga tgccgacaga tgaagttgaa acgacaggtg
     7381 ctccagaaca gccacaagat gagctgtttg aagaagcaaa agcacttgtc gttgaaatgc
     7441 aaacggcaag tatttccctt ctccaaagaa gatttcggat cggttacaac cgagcagcac
     7501 gtttagtaga tgaactggaa gctcatggag ttgttggccc gtcagaagga agcaagcctc
     7561 ggaaagtatt cattgagcag gaagaaacat cagaaacgtt gccggacgat aatgacatgt
     7621 aaaacttgtg tgatgaaggg ttgaaaaacg aataaccaat aaaaagacaa ggcatgatga
     7681 taccaaaaga aaaaatggtt tttttccatc ttttctaata cggtatgatg tcttgtcttt
     7741 ttagtttttg tgagattaaa gttctattcg atttatttgt gaagtattgc attaaggaaa
     7801 tgaatcatgt atagtatgta gcgaaacttt gagaaaaaga gggaaaatac tttggaaaaa
     7861 cagtccattt atggcttgac gaatgaagaa ttaatcaatt ggtttataga aaacggcgag
     7921 aaaaaattcc gagctgccca agtttgggaa tggttgtatc aaaaacgtgt aagtaatttc
     7981 acagaaatga cgaatctatc gaaacaattg atcgaaaaat tatcggagca ttttatcatc
     8041 aatcctctaa aacagatggt cgtccaagaa gcttcggatg gtacagtaaa atatttgttt
     8101 gaactccctg ataaaaacat gattgagact gtactgatga gacaagaata tggcttgtca
     8161 gtttgtgtga cgacacaagt aggatgtaat atcggctgta cgttttgtgc aagcgggctg
     8221 ctcaaaaaga accgtgatct gactgctgga gaaattgttg cacagatcat gatggtccaa
     8281 cattattttg atgagcgcaa tcttggcgaa cgcgtttcac atgtcgttgt aatggggatc
     8341 ggtgagccat ttgataatta cgacaatgta atggactttt tgcatatcat caatgatgcc
     8401 aaaggattgg caattggtgc tcggcacatt acagtttcca ctagtggatt agcacacaaa
     8461 atcaaggaat tcgctaataa cggcttgcaa gtcaatctgg ctatttcctt gcacgcgccg
     8521 aataatgagg tgcgaacatc gatcatgcgg atcaaccgaa gtttcccaat tgagaaattg
     8581 atggaagctg tggatgagta tttagagaaa acaaaccgtc gaatcacgtt tgaatatatc
     8641 atgttgaatc aagtaaatga tagaccagag catgcgcaac aattagcaga tctattaaaa
     8701 gataagaaaa aattagcata tgtcaacttg attccatata atccagtcag tgaacatgat
     8761 caatattctc gcagtccaaa agctgatgta ttgagatttt atgatgtatt gaagaaaaac
     8821 ggcgtaaact gtgtgatacg taaagaacat ggtacagata ttgatgcagc ttgcggacaa
     8881 ttgcgaagca agcaaatgaa aaaaacagtt gccaaataat cgtatcctac tcgttttttc
     8941 aattaccata aaaggagcag ttttcttaat taaggaactg ttcaacttaa ataagagaaa
     9001 agattctata gcgaaagcta taaagctttt tttgacaaga aaaaccctca tcaagcaaag
     9061 aaatgtcctc aatttgatga cagcctgctt gatgggggtt ttagcaatta tttaactgat
     9121 tttcttatat ccttgctggc tttcttgtgt agcatgataa gtttctacgt caagaatggc
     9181 ctgtttaaat ttttctcggg tgatttcata aggcacatgt ttaatatcat ttgttgccat
     9241 ggctttatct aagattgctt ctaaatcggt cgtgacattg agattcatgt cggttaacga
     9301 tactggaagt tggttctttt tcataaacac atagatttta tcaaacaaat cgaactgctg
     9361 atccatcatc aataaggtca gtacaccata actgacagat gctccgtgaa ggtatccctc
     9421 cattttttct agaacagtcg taccgtaata gaatgagtgt gccatagcag aattatagtt
     9481 attgttaact aaaacagaaa ccaatccggt agtaacaatg atatccgaaa cgacttgttc
     9541 aattgcatat gagggacgat cgtcggcact atctttcaat gcttgcgtac cataagtcaa
     9601 gagacgatca atgcacattt ttccgatttg gattcctaat ctatccgtgt agcctagatc
     9661 atcgccacga gcagaaaaag tagattcgac ttctttggat aaagcatcgc caatacctgc
     9721 ccataagtat ttatcaggtg cttcggcaat aattgctgta tcaatgaagg tgtgtacagg
     9781 tggttttgaa ggaaagaaga gtccgtccat tacgccttct tcgttataga tgacacatac
     9841 cgcagtgacg ggcgaacagt tcgaaccaat agtgggaaag gtgaagactg gtttagctag
     9901 tttttcacca atgactttta cagtatcgca agcacggcca ccaccgactg caaacaggac
     9961 gtctgctttt tggacacttt catgctggat caactgttca atatttccat aagttgaatt
    10021 acccccgtac cagagactgg cgacaacctc tatttcctgt gtcaaagcta cttttatttt
    10081 gttttctgcc tttgaaagtg cagtcttccc tccaatcagc actacttttg tcccatattc
    10141 tttgacgatt ccatttgctt tttcatacgc atctgttcca atggtataat ttggtaagaa
    10201 aacactttga ctcatattca tttccttctt tcttcgttga aacgggttaa aattttaaag
    10261 agtgatcgat ctgactgcgg ctgtagatgg agtagaggtg aacctaagac aggataagtg
    10321 atgaataagg tggcatgaac accttgaaat catcaataag tatcctaaaa acgaacaagt
    10381 acaaaaacat tgaaaacgac aataatgaat ttttgttcct cttagtattt ctaccgattc
    10441 cctttgcttt tttgtaatta tctaaaaatt ctaaaaatta agattattat atgaaaacag
    10501 gttttatttg tcaattcata attggttttt tttaaagcaa aagataatct atatcatgat
    10561 gaacaaacag agttttttcc tcca
//
LOCUS       DAXLPC010000087        10495 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.088, whole genome shotgun sequence.
ACCESSION   DAXLPC010000087 DAXLPC010000000
VERSION     DAXLPC010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.088"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(1..459)
                     /locus_tag="ACF3UE_002228"
                     /pseudo
     CDS             complement(1..459)
                     /locus_tag="ACF3UE_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
     gene            complement(711..1070)
                     /gene="rplT"
                     /locus_tag="ACF3UE_002229"
     CDS             complement(711..1070)
                     /gene="rplT"
                     /locus_tag="ACF3UE_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFD3635603.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(1123..1323)
                     /gene="rpmI"
                     /locus_tag="ACF3UE_002230"
     CDS             complement(1123..1323)
                     /gene="rpmI"
                     /locus_tag="ACF3UE_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFD3635604.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(1395..1919)
                     /gene="infC"
                     /locus_tag="ACF3UE_002231"
     CDS             complement(1395..1919)
                     /gene="infC"
                     /locus_tag="ACF3UE_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFD3635605.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(1963..2088)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2239..2871
                     /locus_tag="ACF3UE_002232"
     CDS             2239..2871
                     /locus_tag="ACF3UE_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFD3635606.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2873..3778)
                     /locus_tag="ACF3UE_002233"
     CDS             complement(2873..3778)
                     /locus_tag="ACF3UE_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFD3635607.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(3863..4522)
                     /locus_tag="ACF3UE_002234"
     CDS             complement(3863..4522)
                     /locus_tag="ACF3UE_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFD3635608.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            4838..5782
                     /gene="mvk"
                     /locus_tag="ACF3UE_002235"
     CDS             4838..5782
                     /gene="mvk"
                     /locus_tag="ACF3UE_002235"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFD3635609.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5775..6752
                     /gene="mvaD"
                     /locus_tag="ACF3UE_002236"
     CDS             5775..6752
                     /gene="mvaD"
                     /locus_tag="ACF3UE_002236"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFD3635610.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6765..7850
                     /locus_tag="ACF3UE_002237"
     CDS             6765..7850
                     /locus_tag="ACF3UE_002237"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFD3635611.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7847..8911
                     /gene="fni"
                     /locus_tag="ACF3UE_002238"
     CDS             7847..8911
                     /gene="fni"
                     /locus_tag="ACF3UE_002238"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFD3635612.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(9160..9963)
                     /locus_tag="ACF3UE_002239"
     CDS             complement(9160..9963)
                     /locus_tag="ACF3UE_002239"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFD3635613.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9983..10306)
                     /locus_tag="ACF3UE_002240"
                     /pseudo
     CDS             complement(9983..10306)
                     /locus_tag="ACF3UE_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
     gene            complement(10339..10476)
                     /locus_tag="ACF3UE_002241"
                     /pseudo
     CDS             complement(10339..10476)
                     /locus_tag="ACF3UE_002241"
                     /inference="COORDINATES: protein motif:HMM:NF018513.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
BASE COUNT         3105 a         2220 c         2008 g         3162 t
ORIGIN      
        1 atacctaatg acatcaagat cggcaacaca ataactgcaa tagaaatcac tggtccgatt
       61 cctgtcatcg acatgaatat aacagcggtt acaatacata gtaagctcat cgtgattctt
      121 ggcttgtccc ctccaagttc aactaccttt cgaatcaggg tagctgcgat tccgctatct
      181 actagaacac gcccgaaaaa ggcaccaaag aagacattta ccaagatcga tttggcgtac
      241 tcagctggcc ccgtcgtata gatatgcgtc aacacatcaa ttactccttg cccttccatc
      301 gccgagtttg gtgaaaacgt gtttccgact agcgctaatc ccatccatac agtagccatg
      361 atgacaaaag ccgaccatca agttgtagcc ttttacacag taccagacca tgaaaaagaa
      421 tgagataact aacaaaatac caataataat atcactcatg ttattcctcc gtccattttg
      481 tttttctgat aagcaaacta atatatcagt caaactcatt ctaacttatg tagttagcgc
      541 tttcattaaa ggatgaccat aaatgttcag ttttcaatta aaaaacctta attatgttat
      601 tttagactta tacgttattg tcctgtttca tttgatggag gattgtaaat aaaaaaagag
      661 gaaagaacat aacttttcgt tatcttcttt cctctttata attgtttagc ttatttagcc
      721 aaagcttctt ttgcttggtc agccaatgca gtaaatgctg ctgcatcgtt aacagccaag
      781 tcagctaaca ttttacggtt gatgtcgatt tcagcaactt tcaaaccgtg cattaatttt
      841 gagtagctca agccattcat acgagctgct gcgttgatac gagcaatcca caatttacgg
      901 aagtcgcgtt tcttttgacg acgatcgcga tatgcgtagt tgtatgaatt cattacttgt
      961 tcttttgctg ttttaaataa agtgtgtttt gaaccgtagt aaccttttgc taattttagc
     1021 actcttttac gacgtttacg agttactgtt ccacctttaa cacgtgccat gtataattcc
     1081 tcctaataaa aataaatctt cagattctgt tatttgtact tcttatttca tttttgctag
     1141 ttgttggcga atacgtttga agtcgccact agaaaccatg cttgctttac gcaattgacg
     1201 gcgttgtttt tttgttttgc cgtggaaacg gtgacttgta aacgcgcgga agcgtttcaa
     1261 tccgccttta ccagtacgtt tgaaacgttt tgctgatccg cggtgtgttt tttgttttgg
     1321 catgactata tttcctcctc aaaatctttc gttatccgac tatcggctgt ccaacagcca
     1381 gttagtcatt caaattactt actgtcgttt ttcggtgcca gcgtcaagaa catgctgcgt
     1441 ccgtccattt tcgctttttg ttccactgtt gcaatatccg cagtttcttc agctaagcga
     1501 ttcaagactt tttgaccaat ttctttatgg gtaatggcac ggcctttgaa acggatagaa
     1561 gctttcactt tatcgccctt ttccaagaac ttacgtgcat tacgaagttt tgtattgaag
     1621 tcattcaagt cgatcgtagg acttaagcga acttctttta cattgatcac tttttgtttt
     1681 ttacgcgctt cgcggtcttt cttttgttgt tcgaaacggt atttaccgta gtccatgatt
     1741 cgcgcaactg gtggtttcgc accaggggca actaacacaa gatccaagtt tgcttgttct
     1801 gcaatattca atgcttctgc ttttgtctta actcctaatt gctcaccatc tgaaccgatc
     1861 aatcgtaact ctcgtgcacg aatgccgtcg ttaaccatca tatcctttgc tatggtcatt
     1921 cacctccaaa tattatgaga gaaagaaaag cttaccgaat aaacggcaat aaaaaaacga
     1981 gttctcttac agaacccgcg cgtacttcac ctaatagaac cagtgaaaac tatctagccc
     2041 agtgacatta tcaactaagg cgagaagcgg gtgcttctgc ttttatttct caaccattat
     2101 agtatagcaa aaactaatct ttttgtcaat gtttttcata cagtttgtct tccttttctg
     2161 aaaatgatta gattagcagg ctttctagca gtgattcccg cttctttgct atactaaaga
     2221 aaaacgaggt gaacccacat gaaaaaaatc gaacctattc caccttctct tcctcttctt
     2281 acaaagggag agttttattt agaagatgag gagatcttct ctggtcttct gatcaacgga
     2341 ggtaaccaaa gctatctcga tgccaaaaat atggtattaa gagagagtca tatccaaaaa
     2401 cttacgatgc aaaaaacagg tttacgtcat tttgaatgca gtaatgtcat ttttgaaaaa
     2461 tgtgattttt ccaatctgga gtggattggt ggcagtttcc accaagtcgt gtttcatcaa
     2521 tgtaaattaa caggtacgaa ttttgccgaa agttatcttc gagactgtac tttcactgat
     2581 tgtattgctt cgatggcttc ctttagtagt acaaacttga aagctgtctc cttcgatcat
     2641 tgtcaattag aagacagcga attttatgag gtcacttgga aaaacctttt tttgtctgac
     2701 aatcagttaa ccggttcgaa ctggtttcga acttctctga agggattaga ctttacgact
     2761 aatttcttca caacaatcgc tttatctcaa gattctttgg cgggactaat cgtcaatcaa
     2821 gagcaagcac ttgtgatcgc ccaagccctt ggtttgcaga tcaaagacta gatcaacgaa
     2881 tccgccgcca cagtgcaata agcatccaaa tagataagac caaactgatg atcaaggcga
     2941 tttcccatcc gaaaacggaa tgggtaaagg gtaactggag attcattccg aagaatcctg
     3001 tcacaatagt tggaacggtc aagatcagcg accagaccgt caaaaatttc atcgtgtcat
     3061 tcaagttgtt attcagcaaa ttattataag tgccagagag ctggtctaaa atctgcgaag
     3121 ctaagttcgt catttcaact gcttgtcgtg cttcgatcag tgcatcgtcc aactcttctt
     3181 tttccttttc tgacaacttg cgataaatag ccagtgcctt gatttgttct aaaagtacta
     3241 cattttgttt tgttcctgta actaagtaaa ccaaaccgat ctctaaatct gaaagttgca
     3301 gcagattctt gttcgttgtt ttttctctta atttcagatt aagccgctga cgttcactat
     3361 tcacttcctc gattaaagga aaaaaggaat cagaaatcaa aaacaatgta cgaaacaata
     3421 aactgtatac actcatgtct ggcatccgtt ccaaaagcga tcgaattagt cgaatcacgt
     3481 actcggtatt cggcgtggta aatgtaaaca aaccgtcttc ttttaaaata aaagcgatag
     3541 gactagtttc ataatgatta tcgacttttt gctggtgcgg aacatttgat acaagcagta
     3601 acgcttcatc aaaagaatcg tactctacgc gcgcccgttc atttttatct agagaataag
     3661 tcagcatctc gtcactaatg ccatattctt cttttaagtt tttaacagct agcacatcgt
     3721 tttgctgtac attgatccaa aaattacggt cttgattaaa atagtgtttt tcccgcatac
     3781 tctatcctcc tgacatttgt ttccagtata aagaaaaaag tcgctcaaat aaaggtttac
     3841 cctttatttg agcaactgta aatcaaatgg atactttggt ttggcgaatc tctgctaatt
     3901 tttcttcgat cattttcaag acttcttctt ttgcttgagg atcttccaca aaattatagc
     3961 ggtctccatc gatttggatt tttggacttt ctttgtattc ttcataccat tgatcataac
     4021 gtctgttcaa ttctttgtaa taatcgtata gacttgggtc aaaggacaat tgttcatacg
     4081 aacgaccacg tttttcgata cgctctaaca tcgtatcaaa agatacacga atatgaacta
     4141 ataaatccgg atgtttttta tgggcagcat agggaagttc ttccatcatg ttttccagca
     4201 gttcatcata cacacaaact tctgtttctg ttgctcttcc tagatctgca tttagatgga
     4261 aaagcagtga atcttcataa atcgaacggt ccaatacatt attgtcatct ttcattgctt
     4321 gtttgatgct tgcaaaacgt ttattcaaaa aataaatttg cagcaaaaaa gcatactgtt
     4381 cagggtttgc ataaaataag ggcaagactt cattatcatc aatcgattca taaaatgcct
     4441 gactatcaaa gtgttcagcc atcatttctg ttaaacttga ttttccggca ccaattgtac
     4501 ctgctaaaac gatcacgctc atttacctcc agctcacttc atcactaaat attgtgttta
     4561 actccaacct tttttaaata tacccccaat atctagtagt gtcaattgta ttttttctag
     4621 tcaaagaaga aaaaaagtca aaaaattctt aagaaaaaag tgttttttct ttagaaaacg
     4681 tattcttagt tttacttctg agatggtttt agtaaaataa aggaggaatg ttttttgaga
     4741 cccttagtgg acaaaaaaat tcgtgaagca gcgcaactcg ttttgggcgc tttatttttt
     4801 gcttaaaaat cacttttacg tgagaaggag ttagattatg gcaaactatg gccaaggaga
     4861 atcaagcgga aagatcatat tgatgggcga gcacgcggtt gtttatggag aaccagcgat
     4921 tgcctttcct ttctatgcaa caaaagtcac cgcattcctt gaagagctgg atgcaatgga
     4981 cgatcaactg gtttcttcct actattcagg aaatttagcc gaagctcctc atgcattaaa
     5041 aaatatcaaa aaattattca ttcacttaaa aaaacagcat gacatccaaa aaaacttgca
     5101 actgaccatt gaaagcacga ttcctgctga acgtggaatg ggatcaagcg ctgcagtcgc
     5161 cacagcagtc actcgtgctt tttatgatta cttagcattt cctttgtctc gtgaaatact
     5221 attagaaaat gtccagcttt cggaaaaaat cgcccacggt aatcctagtg gaatcgatgc
     5281 agccgctact agcagcttgc agccgattta ttttacaaaa gggcatcctt ttgactactt
     5341 ttctttgaac atcgatgctt ttttgattgt cgctgataca ggaatcaaag gacaaacaag
     5401 agaagccgtc aaagatgtcg ctcacctctt tgaaacccag cctcatgaaa ctggacaaat
     5461 gatccaaaaa ttaggatact tgacgaagca agcaaaacaa gcaatcattg agaattcacc
     5521 agaaacgttg gcacagacaa tggatgaatc acagtcactt ctggaaaagc tgacaatcag
     5581 caatgatttt cttaatctat tgatccaaac agcaaaagat accggggcat tgggtgccaa
     5641 attaactggc ggtggacgcg gtggctgtat gattgcatta gcacaaacaa aaacaaaagc
     5701 ccaagaaatc agtcaagcac ttgaagatgc gggtgctgct gaaacttgga tacaaggatt
     5761 aggagtacat acctatgttt aaaggcaaag cacgcgcata taccaacatt gctctaatca
     5821 aatattgggg taagaaaaat gaagaactca tccttccaat gaacaacagc ctttcgttaa
     5881 cattggatgc attttataca gagacagaag tcatcttttc tgatagctat atggtagatg
     5941 aattttatct agatggcacc ttacaagacg aaaaagcaac aaaaaaagtc agtcagtttc
     6001 ttgacctttt tcgtaaagaa gccggcctct cactaaaagc ttcagtaatc agtcagaatt
     6061 tcgttcctac cgcagctgga ttagcctcct ctgccagcgg gctagctgct ttagcaggag
     6121 cttgcaatac tgctcttaag cttggattag acgatctctc tctttcaaga tttgctcgac
     6181 gcgggtctgg ttcagcttgc cgaagtattt tcggtggttt cgttgaatgg gaaaaaggcc
     6241 atgacgactt aagttcttac gctaagccag tcccttccga ttctttcgaa gacgatttag
     6301 caatggtttt cgttttgatc aacgaccaga aaaaagaagt gtccagcaga aatgggatgc
     6361 gtcgaacagt cgaaacatcc agtttttatc aaggctggtt agattccgtt gaaggggatc
     6421 tatatcaatt gaaacaagca atcaaaacaa aagatttcca acttctcgga gaaacgatgg
     6481 aaagaaacgg actaaaaatg catggaacga ctttagctgc ccagcctcca ttcacttact
     6541 ggtctcctga cagcttaaaa gcgatggatg cggtgcggca attgagaaaa aaaggcattc
     6601 catgctactt tacgatggat gctggcccta atgtcaaagt tttagtggaa aacagccatt
     6661 tatctgaggt acaagaaaca tttaccaaat tatttagcaa agaacaagta attactgccc
     6721 atgctggtcc aggaattgcg attattgaat aaagggagat ttttatgatt gaagtatctg
     6781 caccaggcaa actctatatt gccggagaat atgcagttgt tgaaacagga catccagcag
     6841 ttatcgctgc agtcgatcaa ttcgtaacag tcactgtaga atccgcacga aaagtcggaa
     6901 gtatccaatc tgcacaatat agtgggatgc ctgtacgttg gacaagacgc aacggagaat
     6961 tagttttaga tattcgggaa aatccttttc attatatcct tgctgctatt cgtttgactg
     7021 aaaagtatgc acaagaaaaa aacattcttt tatcctttta tgatctgaaa gtaacaagtg
     7081 agttagacag ttcaaatggc cggaaatatg gattgggttc tagcggtgcc gtgaccgttg
     7141 caacggtcaa agccttgaat gttttttacg cgttgaattt atctcaattg gagattttca
     7201 agattgcagc actagccaat ttagcagttc aagataatgg ttcctgcggc gacatcgctg
     7261 ctagctgtta tggtggctgg atcgctttct caaccttcga ccatccttgg ctccaagaac
     7321 aagaaactca gcattctatc agtgagttac ttgccctgga ttggccaggt ctatccattg
     7381 agccattgat tgctcctgaa gatttacgtt tattgattgg ttggacgggt agccctgcct
     7441 ctacttctga tttggtcgat caagttcacc gttcgagaga agacaaaatg gtggcttatc
     7501 agcttttctt aaaaaacagt acagaatgtg tcaacgaaat gatcaaaggg tttaaagaaa
     7561 ataatgtaac gttgatccaa cagatgattc gaaaaaaccg acaattactg catgatttat
     7621 ctgcaatcac tggggtcgtc atcgaaacgc ctgctttgaa caaattgtgt aatttagctg
     7681 aacagtatga aggagccgca aaatcttctg gtgcaggtgg tggcgattgc ggaatcgtaa
     7741 ttgttgacca gaaatctggc atccttcctt taatgagtgc atgggaaaaa gcagaaatca
     7801 ctccactgcc gttacatgtc tatagcgatc aaagaaagga aaaccgatga atcgaaaaga
     7861 cgaacatgtt tcactagcta aagcctttca tgataaacaa aaaaacgaat ttgacttcgt
     7921 acggatcatc cataaccctt tgccgcaaat agcagtttct gatgtcgatc taagtacaca
     7981 ggcagttggg tttacactaa gcagcccatt ttatatcaat gcgatgactg gcggaagcga
     8041 aaaaacaaaa aaaatcaacc aagatcttgc aatcgtcgca agagaagcag atttgatgat
     8101 tgccactggt tcagtcagcg ctgccttgaa agacccttct ttagccgata cttatacgat
     8161 tatgcgacaa gaatatcctc acgggaaaat cattgccaac atcggtgcag ggacttctgt
     8221 cgaaagagcc caagaagcta tccgattgtt tcacgcagat gccttacaga ttcatttgaa
     8281 tgcacctcaa gagttggtta tgcctgaggg agaccgtgat tttaccaatt ggaaagtact
     8341 tattcaagag actcaaacag ccattgacgt ccccctcatc gtaaaagaag tcggttttgg
     8401 catgacaaga gaaacgctca atgatctagc tgctttagga gttcatacag ttgatatcag
     8461 cggtcgaagc ggaacaagct tcacccagat cgaaaacgcc cgtcgctcca agcgggaact
     8521 gagttattta gctgactggg ggcaatcgac agtctcttca ttgcttgaag caaatgaagc
     8581 agacacttct atggaaatcc tagcctccgg aggtatccgc aatgcctatg acatatttaa
     8641 agccctttgt ctcggcgcaa atgcagtggg tacttcagga accgtactga cgcatctgat
     8701 gaatcacggc gtagaagaaa ctattatact gatgaagcaa tggcaagaag agcttcgtct
     8761 gctttatact atggtcggcg caacgaatac cgcggcccta caccaacaat cactgatctt
     8821 ttccggacca gtgaaggatt ggtgcgaagc aagagggatc gacttagtga agtatggaag
     8881 acgcacagaa aagagcgtgg gacaaaagta aagaacactt ttatcccacg ctctaaacac
     8941 gtataaacgg cggaagcaaa agcaactcct tcggaaataa gctgaaattc acaaaaattt
     9001 gaaaagcaat tttcgtgaat tccttcttat ttcttggagt taaacgcttc tgtcccagcc
     9061 tcttttttcg aataaatgat gtttaatcag ctgtccttcg gtattcgttc aagccgctga
     9121 tttcacaacc tctccactaa acggtgtact aaagctcttt taaggttgtt ttccgatata
     9181 ggcaagtatg cctccgtcca catacaagac atggccgtta acgaaatcag atgcgctaga
     9241 agccaagaag acagatggtc cagccaaatc gattggctcg ccccagcgtg ctgctggcgt
     9301 acgtccaacg ataaattgat cgaatggatg acgttcaccg ttttcttgtg tttcgcgtaa
     9361 tggagcagtt tgcggtgtag caatataacc tggtccaatt ccattacatt ggatattgta
     9421 ttgaccgtat tcagaagcga tgtttttcgt cagcattttt aatccgcctt ttgccgcagc
     9481 ataagcactg accgtttcgc gtcctaattc actcatcatg gagcagatat tgatgatttt
     9541 accgccgcct ttttcgatca tatcccgaat aactgctttt gaaacgatga atggggcatt
     9601 taaatccacg tcgattactt ggcggaagtc tgccgcatcc atttcgatca tcggtgtccg
     9661 tttgatgatc cctgcattgt tgactagaat atcaactgaa cctacatctt ctttgatctg
     9721 ttgaaccatc gcttgaaccg cttcttcatc ggtcacatcg cagacataac cttttgcatc
     9781 gatgcctgct tctttataat gcgctatacc ttcatcaact gattcttgat tcaagttatt
     9841 aaatacgatt tttgctcctg ctgtagctaa agagcgtgca atctcaaatc caataccata
     9901 gacagcaccg gtgactaatg ctacttttcc atctaaacga aacatatcca tactaaattc
     9961 catcattttc tctcccttat gcttatttta attgatccat ttgcaccata tccatgtctg
    10021 tataggtgat attttctccg cacattgccc agatgaatga gtaattgctt gtacctacac
    10081 ctgaatggat cgaccagctt ggcgaaataa tggcttgttc attgtctacg actaaatgtt
    10141 ttgtttcatc tggtttgccc atcatatgga acacacgtgt atcttcattg gcataatcaa
    10201 aatagacata agcttccata cgacgttcat gtgtatgaca aggcatcgta ttccaagcac
    10261 ttcctggttc taaaatcgta taacccattt ataaatgaca gctatcgctg aagcttctac
    10321 tgctgtaaat atccccgtca agataccacc gataatgatg acaatcaata gaaggctagg
    10381 aatcgcctct tttattattt ttccagcatg agccatctgt cctttttcga caacagggta
    10441 tttattcttt ttagcaacga tgaatgctac tagcatgatt cctagcgccc acaaa
//
LOCUS       DAXLPC010000088        10494 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.089, whole genome shotgun sequence.
ACCESSION   DAXLPC010000088 DAXLPC010000000
VERSION     DAXLPC010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.089"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            132..725
                     /locus_tag="ACF3UE_002242"
     CDS             132..725
                     /locus_tag="ACF3UE_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635614.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            747..2441
                     /locus_tag="ACF3UE_002243"
     CDS             747..2441
                     /locus_tag="ACF3UE_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFD3635615.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            3129..5006
                     /gene="ltrA"
                     /locus_tag="ACF3UE_002244"
     CDS             3129..5006
                     /gene="ltrA"
                     /locus_tag="ACF3UE_002244"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFD3635616.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            5137..5514
                     /locus_tag="ACF3UE_002245"
                     /pseudo
     CDS             5137..5514
                     /locus_tag="ACF3UE_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            5514..6719
                     /locus_tag="ACF3UE_002246"
     CDS             5514..6719
                     /locus_tag="ACF3UE_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFD3635617.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            6735..7379
                     /locus_tag="ACF3UE_002247"
     CDS             6735..7379
                     /locus_tag="ACF3UE_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635618.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            7390..8196
                     /locus_tag="ACF3UE_002248"
     CDS             7390..8196
                     /locus_tag="ACF3UE_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635619.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            8218..8448
                     /locus_tag="ACF3UE_002249"
     CDS             8218..8448
                     /locus_tag="ACF3UE_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635620.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            9005..9280
                     /locus_tag="ACF3UE_002250"
     CDS             9005..9280
                     /locus_tag="ACF3UE_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635621.1"
                     /translation="MEVKIRDIDEKTIQRIDRRCIELSERTGTKWSRNRYLKVLIEND
                     FDHELMDHRKDQFDRLLEKFVDIQTYNTKILEEYIATNNQLIALLIE"
     gene            9322..9744
                     /locus_tag="ACF3UE_002251"
     CDS             9322..9744
                     /locus_tag="ACF3UE_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635622.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKPINESVHARVDPFDPTKFLKR"
     gene            9764..>10494
                     /gene="mobL"
                     /locus_tag="ACF3UE_002252"
     CDS             9764..>10494
                     /gene="mobL"
                     /locus_tag="ACF3UE_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase MobL"
                     /protein_id="HFD3635623.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPDE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNT"
BASE COUNT         3921 a         1662 c         2211 g         2700 t
ORIGIN      
        1 gaccctataa taaccctggt caacgccaaa tttttgcgat tatcgaatct attttcttta
       61 cggataagaa ccactatcat gcgttagatc ctaaccgaaa ttatcatggt acgtataagg
      121 aggatgaata aatgcgagtc aaaggacaaa attcagttga taagaaatcc attttgcagt
      181 ttggaaaacc agaagagcgc tctatcttgg acttatttcc atataaatcc tgtacagaag
      241 agggagtctt aattactaga gaagatcatt ttcagcgtta ttatcgtgtc gtttccactg
      301 acgtggaggg attaaatgaa caagagaaac tagaacgaat gaatcagttg accaccgtca
      361 tgcgtacgta tgtgccaaca attaagttag ttagtttgac cacagagacg gatctaacgg
      421 aacaaatcgt gcaaaagcgg cagttattag ataaaaatcg tatggaacag tcactaggaa
      481 gaaatctaca gcgattaaga aaatatgaaa agaaattagt agaggagatc caggaattaa
      541 aacgggcaga acaagaacgt cctgacttaa gcttcttttt cgttattgaa ggaaagacaa
      601 tcaaggattt acaaactaga aatcgtcagt taatgcgatc tagtggcatt ttagggttaa
      661 aaccactcta caaaaaagaa ttgattaaga ttctttatcg aatgaacaac atgaatgacg
      721 aataaaaaag atggaggaaa tgattcatgc tagatgtgat aaaaacagct ttttcaacgc
      781 aaagtaatca aaaggtgatt gatccattaa aacaacttgg taatcgtgaa atagagattt
      841 taaaatcaaa aggttatgat ttagatttct taaaacaagt gatgccacaa ggtgggttga
      901 attttgatga agaatatgtg acctatggaa atggttattc acgatgtgtg acagtttatc
      961 attacacaaa aaatcctact cttttttggt tggccaatct catgaacaat cctcatacag
     1021 tggccacact agatgttagc acagatgaaa agcaaaaagt gattgatcaa atcaaccgcg
     1081 cattagatga attaaatgat cgatcagata atgaacgaaa agcgactgac cgaaataaaa
     1141 gtgcggaaga atacctggaa ctagcggaat atgcccgaaa attgacttct aatggggaaa
     1201 tttctaaaca agtcaaagtg agagtacatg tttacggaaa tacgatccaa gaagtggatg
     1261 aacgggcgca ggaactgatc gaaaatctaa aagggatgga ttatcgtgcg gtgacttatc
     1321 tgcataaaac caaacgagat tggcaatcga tgtttaccat gttcgatgaa caagctgaat
     1381 ggtttggaaa tatcaaaggg caatcacttc catcgttaaa cattggcgga ggattcccgt
     1441 tccaccacca aacgctaaaa gatccaggag gcacacaata tggggaaacc atgacaggcg
     1501 gcccatttgt ctggaatgcc acgtataaaa atagtgtacg tttatctacc aataccttgc
     1561 ttctaggaat gatgggagct ggtaaatcga ccgttcttaa aatgatcgcg gaagcccatt
     1621 tagctgcagg agactttatt tggggctttg aaaagggaaa agactttatt cctttcttaa
     1681 aggaatataa cggtattatg gtgcgtttag acggatctga cggaatgatc aatcctttag
     1741 agatatttgc cacacggacg tatgatgaag catccagttt atatgacgat ggatcagtca
     1801 aagatttgaa gatcaatgaa gcagcgtcct atcaaacaca cttagacaaa gtggtctatc
     1861 aggtacagtt agtgagtcct cagctaaaag gaacgatgaa agcagaattt aagacctact
     1921 taaatcgttt ttatgaagag tatggaacag taccacgcgg ctttacttcc tcaaattcgc
     1981 gttcaaatac tgatacgcaa gtcacaggga aagatccaga agcttatccg acgttcaaag
     2041 aatttttagc ctttttagga caactggaac taccaggggc ttcccaagag aaaaagaatc
     2101 ggaaagaaga aatggagtct atcgtggaat ccttatgtga gacttatggc atgatttttg
     2161 atggtcatag tacgattcga caccttgacc aacaacagtt ggtctttttt gacattgact
     2221 ctattacagg cctagatcga ggggtacaac aatgtcagat gtacatggcc atgacgttga
     2281 tttggaatca ggcattgatt caaggacgaa gacaacgacg cttaattaaa gaaaaacaaa
     2341 tggaagaaca agacttcaaa cgcttcttgg cgatgattga tgagtgccat aatggtgcga
     2401 cctgttctgc agtgaaaagc tgtgggttgc aagtagtcta aaaactattg taataactct
     2461 tataacgaga agtcaaatga gtgggtaacg ccacaaaggg cttccactga tactccgaca
     2521 tgcaacaagt agtttatgca gaccaacgtt gtgtgaagct cggtgaagtc ggctgaagga
     2581 taccgtaagg taaaagaaat agtgaatacc acgaaagttc tctagaggta aagggtgtat
     2641 ccgataagtc gggtgtccaa aaaaacttaa tatggtgagt atgtacaaac gtactgacga
     2701 actagcgaat gtactgtccg aaaggcatag ctcctagaaa tgggagagac agtgagcaaa
     2761 aaatcactca ttgtgctaac ttgtggttga gtaaaagtcg ttgttatgaa agaccatgct
     2821 gcgttacagg cgtaggagaa gttagggggc aaaagctagc atctaagtta aggcatgtgg
     2881 atagatataa gggaacaggg gaagccatca acatggagag tgcatactcg atgaagtggt
     2941 agtaagaaat atgtgaatga caaataactt actttagtga tggtgaaagt agagtcacga
     3001 ctgatgaagg ttctgtaatg gaactggagg aacaggctcg attcgtctgt aaaagtcatg
     3061 aaacccgttc aaccatggga ttctcgtatg actaaaaagg tcacgagcca attggagcgt
     3121 gataaaccat gacaaaagaa acaagtccaa aagataggaa gttgcggcat gcagaatatt
     3181 atggcatgac ggaaatcttc gataagatat actccaaaag tttgaaggga gataatttca
     3241 agaatctaat gcagattatc atttctgata acaacattgt cctagcatat cgtaatatca
     3301 agagaaatca cggtagtgtg acaagaggag aagatggagt aacgattaaa gatattgaaa
     3361 atctcaaccg taatgaattc gtagaaattg ttaggaagcg attcgcacat tataaccctc
     3421 ggaaagtaag gcgtgtagaa attcctaaat ataatggtaa attaagaccg ttgggtattc
     3481 catcaatatg ggatagaatc gcgcagcaat gcatcttaca agtattagaa ccaatatgtg
     3541 aagcaaaatt caataatcac agctatggtt tccgcccaaa tagatcagca gaacacgcaa
     3601 tagcagattg tatggcccga atgaatcaaa gtcacatgga atatgtggta gatgtagata
     3661 tcaaaggttt cttcgacgaa gtcaatcata ctaaactcat gagacaaatc tggtctatgg
     3721 gtatacgaga caaacagctt ctcttaatca ttaggaaaat gttaagagca cccgtagtac
     3781 ttccaaatgg gaagttgata tacccaacaa aaggaacacc acaaggcgga atacttagcc
     3841 cattacttgc gaacatcaat ctcaacgaat ttgactggtg gatagcaaat cagtgggagg
     3901 aaaaagatgc caaagagcta aaacatcatt ttaggaaaaa tggagcttgg gataaaggta
     3961 atatctatca caagctcaga aagagtacaa ctctaaaaga aatataccta gtgagatacg
     4021 cagatgattt taaaattttc tgtagaaatt ataatgaagc gaaaaaagtt ttctatgcaa
     4081 ctaaaatgtg gttacaggag cgtctaaagt taccaatatc tgaagaaaag tcaaaaatca
     4141 caaatctttc aaaagaagaa agtgaatttt taggctttac gatgaaatta gtgaccaaag
     4201 gtaacaaaaa ggttgttaat acgcatatag gtacaaaagc acaaagcatg attaaagtga
     4261 aactaaaaaa acaaatcaaa cgaattcaaa aaagtcctaa tagcaaagat acctttatct
     4321 atattggagt ctataacagt atggttattg ggattcataa ttacttcaaa attgcgactc
     4381 attgtagtgt agcaatgcga aaaattgcaa gagaactcag accaagtttt gaaatacgac
     4441 tacgagaaca aggaatctca aaagaaggac aatacggaaa gtacgaagga tacaagcctt
     4501 acctacggtc aggacaaata cgatatataa gagggtttcc aatattacca gtagggtata
     4561 ttcaacacag acatccgatg tgtaaaaaaa gaaatattaa taaatacacc gaagaaggta
     4621 gggaagccat tcataagaag caacaaaccg tagaagaatg gaagatatcg tggttgtgta
     4681 gcaatccagt gcttagtaag agagcaacga ttgaatttgc ggacaatcga atttcaaaat
     4741 tcatcgctca aaagggaaga tgtgcagtaa caggtgagga gcttatctta tctgaaatgc
     4801 attgtcatca tattatccct tatcatgaaa gcaaaagtga tagctatgaa aacctagtga
     4861 ttgttactga ggaggttcat cgggtaatac acgctacaca aagtgaaacg attgaggaac
     4921 ttctaaaata tctaaaatta aatccaaaac aaaaagaaaa actcaatgag ttgagattaa
     4981 aagttggtaa cgaagaaata tcttaataaa tatttgtagg acgggaaaac agaatgtctt
     5041 ttatagacga gggaacgccg tatgcggtga aagtcgcacg tacggtgtgg actgggggaa
     5101 aagacggaga taatatcaaa ctcttaccta tcagtatcga ttaatccaga ttttattgaa
     5161 acggtaaatt atgtcacaaa ctttcaacga gaaatgcgta aagtagaagc aatgactgtt
     5221 ttagctacac aatccccaca agaaatggtg ccagaaaata tgtcttctga taacttctcg
     5281 aaactgaaga aagtctttga attttcttct acgaagatct ttatgcgtat ggatgaatct
     5341 attttacgtc atatagaagg attagtgggt aaatcaatga cgaactcaga attagaatcc
     5401 attcctcaac aaaatcaagg agacgctgtg atcaattttg gctcaaaaga aaccattcgt
     5461 gttcatttta gtccgaacaa acgtcaatta aaattgtttg atggaggaaa ataatggaaa
     5521 accaaaatga aagtttaatc aagcagtatg ttaagcgtcg tgcaaagcgg cgcttatttt
     5581 tgtggttgtt tggtacttct gcaggtttga ttactatttt gatcactgtg ttcgtgaccc
     5641 tatttctaat acttgcggcg ggctcgattg ataattcgga ttcagattca agcagtggtg
     5701 gcgaagcttt tacaggagaa tattcggaag gcttaccgat ttataaagaa atcaaaggaa
     5761 gaggcccttt ttctgatgag attgcgcaat atgccgtagg tgcagcagtg aaatataaat
     5821 tattaccaag tgtgatcctt tcgcaatacg gttacgaatc agcgtttggt acatcggcgt
     5881 ccgcaagaaa tgatctcaac tattttggga ttacttggtt tgatggttgt ctgtttccta
     5941 aaggaactgc acgaggaatt ggtggcattg aaggtggctg gtacatgaag tttcccaact
     6001 caaaagctgc attttcctat tacggcttta tggtagccac acaatccaat tttaatgctt
     6061 gtgtaggaaa taaaagccct ggcgcaagct tattgatctt aggacgaggc ggttatgccg
     6121 ctgcaggaat tacggaagat agtccgtatt atacaggttg tatgtcaatt atcacttcta
     6181 ataaattaac cgaatatgat gaattcgcca tcaaacattg gggtgaaggt ggcaataaca
     6241 acggcacgat tactggtgaa tggacgaatc cattccctgg cagcagttta gataaaagtt
     6301 ccttcagcgg tggtcaatta tttggaacga atccaggcgg tgaattccgt ccgaacggct
     6361 tccatgatgg attagatttt ggttcagttg atcatccagg aagtgagatt catgcggttc
     6421 atggcggaaa agtcgtgtac gttggcaatc ctggtatttc aggtttgggc gcgtgtgtga
     6481 tcgtgattaa ttacgatggc ttgaatatgg tgtatcaaga atttgcaaat agtacaggaa
     6541 attctcgagt gaaagtaggc gatcaagtga aagttggtca agtaattggg atacgagata
     6601 cagcacactt gcatttagga tttactcgaa tggattggcg tcaagcacaa ggacatgcat
     6661 tcattgatga tggtacatgg atcgatccgt taccattttt gaatagcagt aaaaaataga
     6721 tcaggagaaa aaatatggaa aataaaacgt taaaaatcgt cttaacagct gcaattagcg
     6781 ttagtttaat cggcaatatt gcgttgtttt ggcagctgaa agaggaacaa gcagcaaata
     6841 cctataaaat tgaagaagtg gctaaaaacg cgtctgagaa gctcaaaaaa aattcctctg
     6901 aggcacaggc gaagatcgac aagttaaatc aaaccatcaa tgagaaaaac caagaaatcg
     6961 atcagctgaa gcaacaagat ggcacaaaag caaaagagga agtaactgaa gcacaaagaa
     7021 agacggcaga agagttcggt caattggcca ttgataaatc attaagcaga aatgaattaa
     7081 cggaaaaact aaaagatgtc gcaacccaag aagtgatcga caaattaagt cctacagacg
     7141 atgatcacca acatgatgat tacggaagtt actcctttac attaggtgac gtgcaaactt
     7201 acgctcaaac aagcagtgta aaagaggaac aaaattttgt cgtatttgtt gattatacaa
     7261 tcggcaatcc gcaattcaaa gatgtcaaac cacaaaaaat aaaaggtgga ttaactgtca
     7321 ctgaaaaaca agtagatggt caatggaaag tcatagactt tagttatttc actcgttagg
     7381 aggaagaaaa tgagtaagaa aaaaggagaa agacaacgtt tcaaaaaacg aaaaagttat
     7441 cttagatggc tgggaatctt tatgattctc ggctttttga ttcttgctag tccgatttat
     7501 acgaatcaga aggtagatat accagatgag gtaagcacga acgccttttt aaacacgaaa
     7561 gagctgacaa tggtttcaaa agaaaaagga gcgaaccagc aattagtttt tgaatttgcg
     7621 atcgatgatg aagatcaaag cttgttaaaa gaactggcta atcttaatta tcgcgtagaa
     7681 gtaaagacag ctaaagggga ttatcaagca atacgagcca aagtgattaa ggtgtctgat
     7741 gattattttg cagtgaagct aacgcatgta ccagaagaat atatcgccat gcgtttaacc
     7801 attattcctg aaaaaattga tccaaaagtg gatatgcaag aaccacaaga tctgatttat
     7861 tacgtgcacg aagataaggt taaagatcaa gtgaaagatg aagattatga acaacacgcg
     7921 atcaattaca aagtgaaagg atacaagaaa gaacaaaaag cagctcaaaa acaaatggaa
     7981 tctttccaag caaccattga tttgaatgaa gaattagtga agaagctaaa agatcaattg
     8041 ccttatcaag tcgcagatga tcaggaaaat actgaaaaca agattaatag ctaccagcaa
     8101 gaaattgaaa catcgaaaac gcaactgaaa gatcaagaag agatcattca aaaacttcaa
     8161 gaaaaaattg atcgtatgac aaaagaaaag atttagaagg acaggtggag tgaaaaaatg
     8221 aagcgaacaa acttggctga caaagatact ttcgctgagc agaaagtatt gattaaagcc
     8281 tatctcaaag ttgtaaaagc taaagaaata tgtcgagaag tgaatttatc taacacaaca
     8341 atatctgagt tgaagaatgg tcgaaagaat ttagatactt taaaattcag atcatttgaa
     8401 gctctatatg tagctgctaa aaaatatttt acagctgata acaaataaaa aacaggagta
     8461 ttttatgtga aaaaagtata taaaaaatgc ttatgaatca gctatatcac cttaaccatt
     8521 tgttaatgag atgggagaaa acattaacca cgattctaac gcaaacatca agcacataaa
     8581 acatttaaca ctcctccttt ctggctgaag atttcaacca aacaggaaga cagcgtatca
     8641 attatagcat acactttttc ttaaattcat ttttcatatg acaaaatatt tccttctaat
     8701 cgacaaagtt agaaggattt tttattgtct aaatacacaa ataaccttaa tttttaaaga
     8761 gcataaggaa acgtgtaccc actttcaaaa taaagtgggt agataggctg tgcctatcac
     8821 gtttctgaaa aaaataaatg accccaaaat tttcaattta tgtgtaggtt tatgggtagc
     8881 aaaaatatga atgtgggcag caaaaagttc atttgtgggt agtaaaattc aaatgtgtgt
     8941 agcaatgtgt gtagctacac acattgctac acacgctata acatatagtg aaaaggagat
     9001 atttatggaa gtaaaaataa gagatattga tgaaaaaacg attcaaagaa ttgaccgaag
     9061 atgtattgaa ttaagtgaac gcaccgggac taaatggagc cgaaatcgat acctaaaagt
     9121 tttgattgaa aatgattttg accatgaact tatggatcat agaaaagatc aatttgatcg
     9181 gttgttagaa aaatttgtgg atattcaaac ttataatacg aaaattttag aagaatatat
     9241 tgcaacaaat aatcaattaa tcgccttgtt aattgaataa taaaaatagt attgtgaatt
     9301 tataaaagga ggaaatcaat tttggcaaaa gcaacaagaa aacatgtata tctttacgat
     9361 atgcatatcg aagtacttga tgaaataatt tctactcatg aagatatatc taattatagt
     9421 gaagcagtca gacatttgtg tatgatgtat gatccaaaaa tcgaagaaaa aataaatcca
     9481 attcaaatta aattgaatgc aatgggaaaa gaaatttcta tattaaccga aatggtttca
     9541 gagtttgcgg atcttcattt gaaagataca ggaatactaa ttggtacaaa ttcaactgtc
     9601 tatcaagaag caaaagagcg tgtggaaggg aaaataaaag cgaatcaaac gaaaaagtat
     9661 tctcctaaga tcaagaaacc aataaatgaa tctgttcatg ccagagtaga cccgtttgat
     9721 ccaacaaagt ttttaaaaag ataaaaagta gaaggggaac atgatgaata aatcgcctgc
     9781 agtcattctc acttgtcaat ttaccttgcc caataaaaaa tctttttcaa catacattga
     9841 ttatatgaca agagaaaaag cgctggaaga aaaggaacga cgcacgccgg acgaagaaca
     9901 ggaactgcaa cgaatcaaga atgctttaga ggatttttat attcctgaag gagaaacttt
     9961 ttcggagagt aagacagata aagaattcag tgaaacgtcg aatgaagctc aatcgttgat
    10021 ggaacatgga atcaattttg acaagttaga ggaacaagat tttaccaaat atctttctta
    10081 tatgacccgt cactatgcgt tagaacaaaa gaaagaactg acgcaaaggg aacaaaaaga
    10141 ataccaacgg ttgaaccaag caatgaaaaa atatcaaaca gagccacata aaaaagcttc
    10201 aggaaatctt cctggagttt tttctatggc ttcagacgaa gtgaaaggaa gtgatctgaa
    10261 ggagatcaaa caaatcttcc aaagagggca acaaaaaggc tcaatcattt atcaagatgt
    10321 tgtctctcac gacaattcgt atcttgaaaa aatgggcttg tacgatccca aaacagatac
    10381 cttagatgaa gaaggattaa aagcagctgg aagaaaaatg atggagacat tattcgagaa
    10441 agaacaattg aatgaaacag gttactggat ggcaacgatt caccgtaaca ctaa
//
LOCUS       DAXLPC010000089        10492 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.090, whole genome shotgun sequence.
ACCESSION   DAXLPC010000089 DAXLPC010000000
VERSION     DAXLPC010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.090"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..265
                     /locus_tag="ACF3UE_002253"
     CDS             <1..265
                     /locus_tag="ACF3UE_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635624.1"
                     /translation="GLTNFEILLELKNEIIRLNMEDDLSMTKFQNYSKSKHLPSVYTI
                     MRRTNKTWEELMSEIGYDYKEIKIKKQRNNLRCRSKKICSRYE"
     gene            694..4287
                     /locus_tag="ACF3UE_002254"
     CDS             694..4287
                     /locus_tag="ACF3UE_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFD3635625.1"
                     /translation="MIRNKKLCLKVALLAVFCQVFFLVGSLTTQAEEITQGTTVSQVS
                     PTSNEVEVQSDLPKETAKEEISTEFVPPTEAPSMNEKSVLDETIGKSQQPGDSPVVAE
                     EIPIETPEVQTIFEKENSSEKSCSTVINEGTESVQSEDSKEATTPIELTKEEMNSNTS
                     LSSEKEEKTALSTESHEPELKKVEESGDTQKEKIKKEAVSSTSSKEVTLIVPQTARSA
                     RVRRATNTAVLGGRKIDWGENIGVISSANNPNFTLNYMVRFEINGQVAFCIEPGVAAA
                     EGQVYTATALENYLKDLNIRKKTSLISYLGYVTSKDKSDEQYIAAQFMIWEVLGTKIP
                     IKNIRIDYDRRKAEIQRLLNNFDVRATFHNQTHTVKIGETLKVKSGNDFLQRVKDIQK
                     PKGVNVSIHDNEVWITITKESPEKAKIHFNQIEALGVPLAYRRPGAQTIGVLNPFVPG
                     DSVVNLTILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQANGKKIKEITLKNING
                     KVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNTIAKDQVIKGTIDLV
                     KVANKDLVDSTNPDNKPKLAGIEISLTSKTTGKVVKTVVTDNDGYATFGKNTVVFDTY
                     ILSETKGKEGYKLFEPFEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKVIALAG
                     TQFKIWDKYANNGKGGYVSMALPNDTEVSDIFTTNEKGYFVTTDTLKYGKNRYELREI
                     KAPEKYVLNKTPYVFSVTDDTNTIQLIYFANRLAKANVEVFKYDTSTNFDQKTAIAGV
                     EFDLFKKDETGTTFVGTFKTDKKGKINVKDLLVGDYFFKEVKPLAGYLALDKDVPFTV
                     TVDKDGTVIALEVENKRIPPKIGTTAIGKYTNQQKVTPLKKVTITDTVKYSNLIIGKT
                     YTVNGVLMDKEESITAGKDVPLLVNGKQITASKVFVAKNPNGMISLDFVFDASALAGK
                     EIVVFENVYRDGRLVASHTDIHDKGQTVRIVNPMIHTKATGQNGEKQLQALPNQKVKE
                     LVQLNDLIVGQTYKVLVQGYITPDGVKLDGTSAEKIFKADKTTLEFLFEFLVDGRKLA
                     GKGLSFAEWLEAQSEPKDENDYEVRFEQIANHNVDLKSEDQTVYFVEVPKVPEPKIPE
                     KSQPFKEVKQASVVPMLPKTGSEDTVLWMIIGVLFVLAAGLTFYELRKVKD"
     gene            4387..5325
                     /locus_tag="ACF3UE_002255"
     CDS             4387..5325
                     /locus_tag="ACF3UE_002255"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3635626.1"
                     /translation="MKKKERKKRMKKLFFACLFSSVVLAGGINVFADEIGITPVTPPV
                     IEETTPVVPIPDISKIDESVPDQPTPVDPDISSEVTEPTTPVVPDITENSENETPVVS
                     PSTGETTNDKDTTPTTSESYSGTSSVDNDSKIDDFSSSSTTIDTPKETEKKNDLGAPK
                     NLTPENHIKTVSEKEMTVSVSSDGKIVQGTGTEKSIPIVTSNLEEINHVPTSETPLQV
                     ATGQAIVGVQDGVPLVQDNQGNLVEDLSIPVKKLPSGNIEIKTIDGKTKVLPKTGEEL
                     QISLTILGSLLTAVTGGIFYGKKQWRHLRHMFKKTI"
     gene            5344..5694
                     /locus_tag="ACF3UE_002256"
     CDS             5344..5694
                     /locus_tag="ACF3UE_002256"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635627.1"
                     /translation="MGLSYVAISQEEVLGKCFNQKHVGSTGERDHRGNMKKVEWEIFQ
                     MNSEKMGEIEVRVAVGGAPKAMRYNAEVLLANPRISRRADVRNIGNDGETNKIARNRF
                     YLLVDRVEVKGGNN"
     gene            5694..6125
                     /locus_tag="ACF3UE_002257"
     CDS             5694..6125
                     /locus_tag="ACF3UE_002257"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF961 family protein"
                     /protein_id="HFD3635628.1"
                     /translation="MTLEFDQGIVPGLVKETLGEIYFVKAQRPRMLYEDNENTGEIKE
                     RPVEFSSATQETMFVVNFPPKTNLDGLSFGDVVELEEVEFRFWISIDRESMSNRAEND
                     LKVSALRYKKTGKNVFQTSSSTRATYVKEKQDSNKESAKKE"
     gene            6393..7712
                     /locus_tag="ACF3UE_002258"
     CDS             6393..7712
                     /locus_tag="ACF3UE_002258"
                     /inference="COORDINATES: protein motif:HMM:NF013727.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFD3635629.1"
                     /translation="MFQYKGIRIRNRHKYASERFIFYLMLPVLLLMSGFFSLFYTTIT
                     WEWCCIYWIIAFGLAGLFAYMCLYFYFYNVYQRLVHKGKLAKMIHSRRLILERVLKNG
                     RRKVVYYPKIFYHYKNGLIHVRLPLDLGPFQDRFNEMAGQLEEAFFCDLVEEQREKNY
                     ICYTFLYDVEKNRIGIRDITVKDGIITLMKNVQWAFNKAPHAIIIGSTGGGKTYFIMS
                     LIYALLPYGTFDICDPKRADLASLEKIPIFKDQVFYGGGILSCLINLAKETANRYDFL
                     REQPEYELGYDYTYYHLTPHFLVIDEWAAYYASLDTKEKKKAMGCLNQIALMGRQCGV
                     FLILGTQRPDTKYLDGAIRDNFGLRVTLGRVSKAGYKMIFEHTVKSLFNKPIKGRGYI
                     DSGTDQVREFYAPFIDITRFNFFAEFKQLSDQLMAEKIKETKEGKNV"
     gene            7705..7869
                     /locus_tag="ACF3UE_002259"
     CDS             7705..7869
                     /locus_tag="ACF3UE_002259"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635630.1"
                     /translation="MYEEIPATCGTRLGIKDLMIDSFLAIVFSEKRLSFFINKKVENR
                     WRVERMYPTS"
     gene            8408..9583
                     /locus_tag="ACF3UE_002260"
     CDS             8408..9583
                     /locus_tag="ACF3UE_002260"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFD3635631.1"
                     /translation="MDGTQLKQMRLSRNLTQKLVADTLGWPQSFLSMIENDQRSCSKE
                     QEEALCEFYANFSSFTSLEIKFDYVRVRVPTNDTKTVVEEILGMDFNSFFYAETRLYG
                     YIEMYQKGMIRVLNSKKGDDKGVLIELSGQGCRNYESVLDERNDSWYQFFTRCVSFNG
                     VSRRIDIAVDDFEELFSLHEFAQKLNRGEFDSKFRTWRFQEEKQLLDNLSSGLSVYLG
                     SSQSLMYFCFYQKNYEIAKKQKLPLEEVEVKNRYEIRLRDAKAVSFIEQYLNKVDFSD
                     LTMGILANQLIMFEGEKNTNVWKPWGKLIQNVGKVNLTVTPEKPNYNRKLMYLKTQPA
                     RTMKIVKTVDEILGLNRFGEILEETELREQDEKIVEDEVRAVYEYIQENPDAIHYLL"
     gene            10088..10285
                     /locus_tag="ACF3UE_002261"
     CDS             10088..10285
                     /locus_tag="ACF3UE_002261"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635632.1"
                     /translation="MGQYFLTGVWYVLKLVIILGIAYICFRILLSGEGMPTPKDFIIS
                     VLNFVADQIQVIIHWAQQRFG"
BASE COUNT         3809 a         1469 c         2104 g         3110 t
ORIGIN      
        1 gggattaact aattttgaga tacttttaga gcttaagaat gaaataatta gacttaatat
       61 ggaagatgat ttatctatga caaaatttca aaactattca aaatccaaac atcttccatc
      121 tgtatataca attatgagac ggacaaataa gacatgggaa gaattgatga gcgaaattgg
      181 gtatgattat aaagaaataa aaataaaaaa acagagaaat aatttgcgtt gtagatcaaa
      241 aaaaatatgt tcaagatatg aataaacaaa gtatttttca gcatattttt atctgtacca
      301 ttattttaaa tatccatagc agtttattca tgatttatga ggtttaaaat acaatactga
      361 attcactgct tattttcatg ttactgctta aactttgtat tttaatagaa aatagagatg
      421 tgaacgaaaa atatttattt ctattacaaa aggtaaaaaa tttgatttaa aagctaaatg
      481 tacagatgag ttttgaattt ttctccttca aattcaaaat gagagtagta ggtatgatag
      541 aaatatatca aatattaaga tagatacaat atgcataata ggctatgctt ctttagattt
      601 tttgattaag aacacaataa atagtttacg tcgatactta ttaagttatc gacgtttttt
      661 ttataaaaaa tttataaaag gaggtttctt gatatgataa gaaacaaaaa gctttgcttg
      721 aaagttgctt tattggcagt tttttgtcaa gtattttttt tggtaggctc actgacaaca
      781 caagcagaag aaataactca aggaacaact gtttctcaag tttctcctac ttcaaatgaa
      841 gttgaagtac aatccgattt accaaaagag actgccaaag aagagatatc gacagaattt
      901 gttccaccaa cagaagcacc ttcaatgaac gaaaaaagcg tactcgatga aaccatcggt
      961 aaaagccaac aaccaggaga tagtccagtt gtggcagaag aaataccaat agaaacacct
     1021 gaagttcaaa caatttttga aaaggaaaat tcatcagaaa aaagttgttc tactgtaata
     1081 aacgaaggaa cagaatcagt tcaatcagaa gattcaaaag aggcaacgac tccgattgaa
     1141 ttgacgaaag aagaaatgaa ttctaatact tcactttctt ctgaaaaaga agagaaaaca
     1201 gctctttcga cagaatccca tgaacctgaa ttgaaaaaag ttgaggaatc aggtgataca
     1261 caaaaagaga aaataaaaaa agaagctgtt tcttctactt cttcaaaaga agttacattg
     1321 attgtaccac aaaccgctcg aagtgcacgg gtgcgacgtg caaccaatac agcagttttg
     1381 ggtggtcgga aaattgattg gggcgaaaat attggtgtta tttctagtgc caataatccc
     1441 aatttcactt taaattacat ggttcgtttt gagattaatg gacaagtagc attttgtatt
     1501 gaacctggtg tcgcagccgc agaaggtcaa gtttatacag ctactgcttt agaaaactat
     1561 ttgaaagatt taaatatacg aaaaaaaaca agcttgatct cttatttagg atatgtcaca
     1621 agcaaagaca aatccgatga acaatacatt gcggcacaat ttatgatttg ggaagttttg
     1681 ggcacaaaaa ttccaattaa aaatatccgt attgactatg atcgtcgaaa agcagaaatt
     1741 caacgtttgc ttaataattt tgatgtaaga gctacttttc ataatcaaac acatacggta
     1801 aaaattggcg aaacgttaaa agtaaaaagt ggcaatgact ttctacaacg tgtaaaagac
     1861 attcaaaagc caaaaggtgt taatgtatct attcatgata atgaagtatg gattacaatc
     1921 acaaaagagt caccagaaaa ggcaaaaatt catttcaatc aaattgaagc attaggcgtg
     1981 ccattagcgt atcgtcgtcc aggtgctcaa acaattgggg tgctgaatcc ttttgtacct
     2041 ggtgactctg ttgtcaattt gaccattttg aaacaaggaa acattcgcgt ctttaaagaa
     2101 gatgcagaaa ccggtgtgaa agcacaaggt gcagcttctt tagaaaatgc agtgtatggc
     2161 ttgtatcaag caaatgggaa gaaaatcaaa gaaattacat tgaaaaatat caatggcaaa
     2221 gtacaggcag aaatcaaaga tcttgatcct ggtaaatatg ttttaaaaga gatcaaagca
     2281 ccaaaaggtt atgtactttc tgatgaagca attgaaatcg tcgttgaacc tggaaaaact
     2341 gtcaatacga tcgcaaaaga tcaagtgatc aaaggaacca ttgatttagt caaagtcgca
     2401 aataaagatt tagtcgattc aaccaatcca gacaacaaac ccaaattagc tggtattgaa
     2461 atctctttga cgtcaaaaac aactggaaaa gtggtgaaaa cagttgtgac agataatgat
     2521 ggttacgcta cttttggtaa aaataccgtt gtctttgata cgtacattct ttctgaaacc
     2581 aaaggaaaag aaggatataa actatttgaa ccattcgaag tcacaatttc tgaaaatgga
     2641 caaaccttcc attatgtttt agaagacaaa gtaatcgaac aacgtcttaa agtggtgaaa
     2701 gtggatcaag aaacagggaa agtcattgct ctagctggta cccaattcaa aatttgggat
     2761 aaatacgcaa acaatggtaa aggtggctat gtatcgatgg cattaccgaa tgatacagag
     2821 gtttcagaca tatttacaac aaacgagaaa gggtactttg tcacaacgga tacattgaaa
     2881 tacggaaaaa atcgttacga gttgcgagaa atcaaagcac ctgaaaaata tgttctaaat
     2941 aaaacgcctt atgtcttttc agtaacagac gacaccaata cgattcaatt aatctacttc
     3001 gctaaccgtt tagcgaaagc caacgtagag gttttcaaat atgatactag tacgaatttt
     3061 gatcaaaaaa cggcgattgc tggtgttgaa tttgacctat tcaaaaaaga tgaaacaggc
     3121 acaacctttg ttggtacatt caaaacagac aaaaaaggta aaatcaatgt gaaagactta
     3181 ttggttggcg attacttctt taaagaagtg aaaccattag cagggtatct ggccttagat
     3241 aaagacgtac catttactgt aacggttgat aaagacggta cagtgattgc actagaagtg
     3301 gaaaacaaac ggattccacc taaaattggt actacagcta tcggtaagta tacaaaccaa
     3361 caaaaagtga ccccattgaa aaaagtaacg attacagaca ctgtaaaata cagtaatcta
     3421 atcatcggaa aaacttatac cgtcaatggt gttttgatgg ataaggaaga atctatcaca
     3481 gcaggaaaag acgtaccgtt gttagtaaat ggtaaacaaa ttaccgcaag taaagtgttt
     3541 gtcgcaaaaa atcctaacgg aatgatttcc cttgactttg tctttgatgc tagtgcatta
     3601 gctggaaaag agatagtcgt atttgaaaat gtctatcgtg acggacgctt agttgcgtct
     3661 catacagata ttcacgataa aggacaaacg gttcgtattg tgaaccctat gattcataca
     3721 aaagcaacag gtcaaaacgg cgaaaaacaa ttacaagctt taccaaatca aaaagtgaaa
     3781 gaattggtac agttgaacga cttaattgtt ggtcaaacgt acaaagtgct cgtacaaggt
     3841 tatattacac ctgatggtgt gaaattagac ggtacaagtg ctgaaaaaat tttcaaagca
     3901 gataagacaa ctttagagtt cttatttgaa tttttggtag atggacgtaa gctagcaggc
     3961 aaaggattat cttttgcaga atggttagaa gcccaaagtg aaccaaaaga tgaaaacgat
     4021 tatgaagttc gatttgaaca aatcgcaaac cacaacgtag acttaaaatc agaagatcaa
     4081 acggtttatt ttgtagaagt tccaaaagta ccggaaccaa aaattcctga aaaatcacaa
     4141 ccttttaaag aggtgaaaca agcttcagta gtaccaatgt tgccaaaaac aggatcagaa
     4201 gatactgtat tatggatgat cattggtgtg ctatttgttt tagcagcagg tcttacattt
     4261 tacgagttac gcaaagtcaa agactaagta ggacaaacaa gcggttagat gcctaatcgc
     4321 ttgtttggtt ttaaaaaagt tattgcataa gtaacctttg aaaagataag aaatgatctt
     4381 tgttttatga agaaaaaaga aaggaaaaag agaatgaaga agctattttt cgcatgttta
     4441 tttagttccg tagttcttgc tggtggaata aacgtttttg cagatgaaat aggtattaca
     4501 ccagttacgc cacctgtgat agaagaaaca acacctgttg ttccaattcc agatatttct
     4561 aaaatagatg agtctgttcc ggatcaacca actcctgttg atccggatat atcttcagaa
     4621 gtaactgaac caacaacacc tgttgttcct gatataacgg aaaattcaga aaatgaaaca
     4681 ccagttgtat cgccttctac tggagaaaca acgaatgata aagatactac accaactacc
     4741 agtgagtctt attcgggaac tagttcggta gataatgatt caaaaataga cgattttagt
     4801 tcttcatcta ctacaataga tacaccaaaa gaaacagaaa agaaaaatga tttaggagct
     4861 cccaaaaatt taacacctga aaatcatata aagactgtat cggaaaagga aatgactgtt
     4921 tcagtcagtt cagatggaaa aattgtacaa ggaacgggta ccgaaaaatc aattcctatt
     4981 gtgacaagta atttagaaga aattaatcat gtcccaacat ctgaaactcc tttacaagta
     5041 gcgactggtc aagcgattgt tggggtacaa gatggtgtac cacttgtaca agataatcaa
     5101 gggaatttgg tagaagattt atccattcct gtaaaaaaac tacctagcgg caatattgaa
     5161 atcaaaacaa tcgatgggaa aacaaaagta ttgccaaaaa caggtgaaga acttcaaatt
     5221 agtttaacta tccttggttc tcttttaaca gcagtaaccg ggggcatttt ttatggtaaa
     5281 aaacaatggc gtcatttgcg tcatatgttt aagaaaacta tttagtaagg agagagaata
     5341 aaaatgggtt tatcttatgt tgcaattagt caggaagaag tattgggaaa gtgttttaat
     5401 caaaaacacg ttggctcgac aggtgaacga gatcatcgag gaaatatgaa gaaagtagag
     5461 tgggagattt ttcagatgaa ctctgaaaag atgggagaaa ttgaagtgcg tgtagctgtc
     5521 ggtggtgcgc ctaaagccat gcgatacaat gcagaagtgt tactggcaaa tcctagaatt
     5581 tctcgtcgag cagatgtacg aaatattgga aatgacggtg aaacaaacaa aatagcacgt
     5641 aataggtttt atttgttagt cgatcgtgta gaagtaaaag gaggaaataa ctaatgacac
     5701 tagaatttga tcaaggaatt gtcccagggt tggtaaaaga aacactagga gaaatctatt
     5761 ttgtcaaggc acaacgtcca cgtatgctgt atgaagataa tgaaaacaca ggagaaatta
     5821 aagagcgtcc agttgaattt tcaagtgcta cccaagaaac aatgttcgtg gtgaattttc
     5881 caccaaaaac aaatttggat ggattaagtt ttggcgatgt ggtggaatta gaagaggttg
     5941 aatttcgatt ttggatttct attgatcgcg aatcaatgag taaccgagca gagaatgatc
     6001 tgaaagtatc tgcgcttcgt tataaaaaaa cgggaaaaaa cgtttttcaa acgtcttcct
     6061 ctactcgtgc aacatatgta aaagaaaaac aagactcaaa taaagaaagt gcaaagaaag
     6121 agtaatggtt tccattgctc tttcttattt taaagctaga agaagtagct gatgtggaga
     6181 aaattgaatt ggctggctat attattggga taaatttttg aatttttaag aatttagata
     6241 gtggttagat acgattgatt ctttgtgtat tttgtattat ttaagtattg tgtggtattt
     6301 acattaagtt aatattgatg ttgttagtgt taatgaaggt tttcttttat ccaatacatt
     6361 agtcactcta tgatgcgagg agatgagaat aagtgtttca atataaaggt attcgtattc
     6421 gaaatcgaca taaatatgct tcagaacgat ttatttttta tcttatgttg ccggttctgt
     6481 tgctaatgag tggatttttt tctctctttt atacaacgat cacatgggaa tggtgctgta
     6541 tttattggat aatcgcattt ggtttagctg gtctatttgc gtatatgtgt ttgtattttt
     6601 acttttataa tgtttatcag cgattggttc ataaaggaaa attagcaaag atgatacata
     6661 gtcgtcgatt gattcttgaa agagtattga aaaatggacg gcggaaagtg gtgtattatc
     6721 caaaaatttt ttatcactat aaaaatggct taattcatgt tcgattgcca ttagatttag
     6781 gtccctttca agatcggttt aatgagatgg ctgggcaact agaagaagcc tttttttgtg
     6841 atttagtaga agagcaacga gagaaaaact atatttgtta taccttttta tacgatgtgg
     6901 aaaaaaatcg tattgggatt cgagatataa ccgtaaaaga tggcataatc accttaatga
     6961 agaatgttca atgggcattt aataaagcac cacatgccat aattatagga agtactggcg
     7021 gtgggaaaac gtattttata atgtctttga tctatgcatt attaccgtat ggtacgtttg
     7081 atatttgtga tccaaaacgt gcagatttgg ctagtttaga aaaaatacca atttttaaag
     7141 atcaagtttt ttatggtggt ggtattttat cttgtttaat aaatctagct aaagaaactg
     7201 ctaatcgata cgatttttta agagaacagc ccgagtatga attagggtac gattatactt
     7261 attatcatct aactcctcat tttttggtga ttgatgaatg ggcagcatat tatgcatcgt
     7321 tagatactaa agaaaaaaag aaggcaatgg gatgtttgaa ccaaattgct ttaatgggtc
     7381 gtcaatgtgg cgtgttttta attttaggta cccaacgtcc agatacaaag tatttggacg
     7441 gcgcgatacg agataatttt ggtttacgtg taacactggg aagagtatcc aaagctgggt
     7501 ataagatgat ctttgaacat acagtaaaat cattatttaa taagccgatt aaaggtcgtg
     7561 gttatattga ttcgggaacc gatcaagtac gagaatttta tgcgccattt atcgatataa
     7621 caagatttaa cttttttgcg gaatttaaac aactatctga tcaattaatg gctgaaaaaa
     7681 tcaaggagac gaaagaggga aaaaatgtat gaagaaatcc cagctacatg tggaactcga
     7741 ttaggaataa aagatttaat gattgactct tttttggcaa ttgttttcag tgagaagaga
     7801 ttaagcttct ttatcaataa aaaagtagag aatcgttgga gagtagaacg tatgtatcca
     7861 acgagttaac tgattggtta cagttgcctt atgacaatta tcgaaggcga atatgacggg
     7921 tttttacttc aaataaaagt gctcgatcct atagtgacca aattgtcgaa aaagcagcgg
     7981 aacagcctgt tttttatgga cgattcaaag gactttcctg ttcttatgtt aaaagtaaag
     8041 accggtctcg actgtaccta caagtagagg atattaactt gtcctttgcg ttgccagaaa
     8101 attaaatttg tcctcattag aatacggaag atgctgtgcg tatgctccac aagcaaacaa
     8161 gcctcagggc ggaaggacgc ggaagcgtcc tagcgttagc gaaagccctg aggtgcaggg
     8221 tgcgttgtgg ggcgtgcgcg tagcgcacgc ctaaaacccc catattctaa caggggggta
     8281 gaatttatat tcggtggcaa agatgggtga ttgaaacatt gatataacac tattttgctt
     8341 caaaaatttt gtgatatttt tcttcgcttt gtaacataaa atatcacaaa agaaaggaaa
     8401 gatatatttg gatgggacac aattaaagca aatgcggtta agtcggaatt tgacacagaa
     8461 attagtggca gatacattag gatggccaca atctttttta tcaatgatag aaaatgacca
     8521 acgaagttgc tcgaaagaac aagaagaagc actttgtgaa ttttatgcga atttttcaag
     8581 ttttacgagt ttagaaatta aatttgatta tgtccgtgta cgagttccga caaatgatac
     8641 gaaaacagtt gtggaagaaa ttttgggaat ggattttaac tctttttttt atgcagaaac
     8701 ccgcttatat ggttatattg aaatgtatca aaaaggcatg atccgtgtat taaattctaa
     8761 aaaaggtgac gataaaggag tgttgatcga attatctggt caaggctgtc ggaattatga
     8821 aagtgtactg gatgaacgaa atgatagttg gtatcaattc tttacacgat gtgtctcttt
     8881 caatggtgtg tctcgaagaa ttgatattgc ggtagatgat tttgaagaac tattttcttt
     8941 acatgaattt gcacaaaaac taaatcgtgg cgaatttgat tcaaaatttc gaacctggcg
     9001 atttcaagaa gaaaaacagt tgttagataa tctaagtagt ggcttatctg tttatttagg
     9061 tagttcacaa agtttgatgt atttttgttt ttatcagaag aattatgaaa ttgcaaaaaa
     9121 gcagaaactt ccgttggaag aggtcgaggt aaaaaatcgt tatgaaattc gcttacgtga
     9181 tgcaaaagcg gtcagtttta ttgaacaata cttaaataaa gtagattttt cagatttaac
     9241 gatggggatt ttagccaatc agttaataat gtttgaggga gagaaaaaca caaatgtgtg
     9301 gaaaccatgg ggaaaattga ttcagaacgt tggaaaagtc aatttgacag tgacaccaga
     9361 aaagccaaat tataatcgga aattgatgta tttaaagaca caacctgctc gtacaatgaa
     9421 gattgtaaaa actgtggatg aaattttagg attgaatcga tttggagaaa ttttagaaga
     9481 aacagaatta cgggaacaag atgaaaaaat tgtagaagat gaggtgcgtg ctgtttatga
     9541 atatatacaa gaaaatccag acgcgattca ttatttgcta taaagcttgc gataagatgg
     9601 gtgaaacatg attaaaacag aagaccaatg atggggagag tatatgattg cttgttaacg
     9661 attaataaaa gaaacgatcc tatgtgttgg aaatgatcta cagttattta aagaatattt
     9721 agattatcaa caatcaatca aaatgttaca tgtagaaata ggggaagtat taagctaccg
     9781 tattagtgat tcgttaaaat attcgttgac aaagatttat ttatatgcaa cacaagtatg
     9841 tggatatacg aaaaagcagt aaaaacaatg atgaaatatg acgatttgcc aagtaagata
     9901 tcctagattt acaacaagta ttggaagaaa aactatatct atatatgaaa aatagagggg
     9961 aaaagaaatg attcgatttt tattttctgt aggttggcat tttttgaaat tactgtttct
    10021 tttagtttgt attgtctgta gtattatttg gttattaaca ctttaaagaa aggaatatgt
    10081 tggaaaaatg ggacagtatt ttcttaccgg tgtttggtat gtattgaaat tagtgattat
    10141 tttaggtatt gcctatattt gttttagaat tttattatcg ggagaaggaa tgccaacgcc
    10201 aaaagatttt atcataagcg tgttgaattt tgtggcggat caaatacaag tgataattca
    10261 ttgggcgcag caacgttttg gataaaaaaa tatatttaaa aaatttaatg tttagaagtg
    10321 ggctatgtga tagaaaattt cgagtataag ttatctagat tgccaaagaa aaagggagct
    10381 acacaaaaag agctggctaa taaattaggt gtcaatgtac aaagcgcttc taatgttgag
    10441 gaagataaga gctaactaca tttagtaatt tagaaaaaat agtttctttc tt
//
LOCUS       DAXLPC010000090        10412 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.091, whole genome shotgun sequence.
ACCESSION   DAXLPC010000090 DAXLPC010000000
VERSION     DAXLPC010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10412
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.091"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            112..852
                     /locus_tag="ACF3UE_002262"
     CDS             112..852
                     /locus_tag="ACF3UE_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635633.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(1143..1811)
                     /locus_tag="ACF3UE_002263"
     CDS             complement(1143..1811)
                     /locus_tag="ACF3UE_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3635634.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            1945..2232
                     /locus_tag="ACF3UE_002264"
     CDS             1945..2232
                     /locus_tag="ACF3UE_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635635.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            2648..4186
                     /locus_tag="ACF3UE_002265"
     CDS             2648..4186
                     /locus_tag="ACF3UE_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFD3635636.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTSTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            4183..5148
                     /locus_tag="ACF3UE_002266"
     CDS             4183..5148
                     /locus_tag="ACF3UE_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635637.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            5135..6457
                     /locus_tag="ACF3UE_002267"
     CDS             5135..6457
                     /locus_tag="ACF3UE_002267"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD3635638.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      6520..6624
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6698..7441
                     /locus_tag="ACF3UE_002268"
     CDS             6698..7441
                     /locus_tag="ACF3UE_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3635639.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            7456..8448
                     /locus_tag="ACF3UE_002269"
     CDS             7456..8448
                     /locus_tag="ACF3UE_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3635640.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            8460..9197
                     /locus_tag="ACF3UE_002270"
     CDS             8460..9197
                     /locus_tag="ACF3UE_002270"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635641.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            9187..9909
                     /locus_tag="ACF3UE_002271"
     CDS             9187..9909
                     /locus_tag="ACF3UE_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFD3635642.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(9993..>10412)
                     /locus_tag="ACF3UE_002272"
     CDS             complement(9993..>10412)
                     /locus_tag="ACF3UE_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFD3635643.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3457 a         1792 c         2171 g         2992 t
ORIGIN      
        1 tatttatgaa attcatcgct attttcttaa aataatcagc gcattgctac tgaaaacaat
       61 gaatctgtgc tattattgag aaaagttcca tttttgagaa ggatggtttg aatgaaagaa
      121 atcagacgaa aacatttccg ttttcctgcg tacgatgatg agttaggcgt aaaattaacc
      181 aacgacaaga agcgagtatt atttgacgga caagaagatc ttttgactga acagaatcag
      241 tccccgtttg aacagatgaa agaatttcat ttcacgaaca cgaacaccga gaaaatccgt
      301 cgcaagcgtc gtgcaacaaa tggattgaag tcagctccgc gtaaggaaaa tttggaaaag
      361 cataaaggaa aattaccgga ttataccggc cattaccaat cagaaatcac atcgacagga
      421 cgaaaaaaac tttttggtga ttcctctcgt tctgtcagac aaagtgaaac aaggacagag
      481 tccaagcata ctacacgaaa cgcatctgtt gacacgaagg tgcgggagcg ttcttatttt
      541 gttcctaaat atgtacccgc atcgattatc ccagacccta gagaaagcaa aatttctgag
      601 gatcatttaa tcgaatcgat gaaaaaaacg gatgactctt atctgttgtt cgatacagaa
      661 ccgacgccgt atcaagaaaa aagaaatggt gagccgtctg tacgaacatt caatcgaaca
      721 aaaacgttag aggaaacaaa gcagtcagaa gaaaaaaaat cgaaaaaaag ccatggtatc
      781 ttagaacgct cattacaagg attgatcgat gatcaaggaa actctttggg agaaaatagc
      841 tattttaaat aagtgatata caaatttata ttcggctaca gttggaaagg aaacgctgcg
      901 gcgtttcctt attttatact ctatccgaaa gtttatatcg tatcctcaaa tttttttgag
      961 tttaagcgaa ttttttctcc caataagtaa gaaaataatg gcaaaataaa aaaacaaact
     1021 attttcgcag atcgtttgca aaaatagttt atttttttat aaagaagatt ttactgaata
     1081 atatcatttt agtttacata atgatatttc tgtaaattaa ataaagtagt gaaaaataag
     1141 aatcagtgct ctaactgttc aagaggatca agtggttcaa atgtttctgt agtctgtttt
     1201 gcttccaatt ggggcaaaac agatccaatt tccagatact tcactttatt caatgtataa
     1261 gatagaatag aacagctaag taatgtatac agaaaatgtg tgagatccaa ataaagcaag
     1321 gagacaacta aaataccaaa agtaatcaag aaaagacttt tgccaatctt aatatgaaaa
     1381 tatttttcaa tggcttgata aatgatatct gttccgcctg tgcttccgcc gaatcgaaag
     1441 acgagaccgc aaccaatgcc agaaagaata cctgtcatca aactattgat cagtagacta
     1501 tctacagcaa aatgtatatg aaggctctcc cataaatgta aaaagaaaac tagcgcaaat
     1561 gttccgacga tcgtccggag aaaagcgtgt tttccaaaaa gaaacaatga gataagcaat
     1621 aaaggtaaat taaaaagcag tgaagtgaca gaaggagcga atccaaaaag attatgcaaa
     1681 agcaaagcaa taccagtaac cccaccatct gccagcttag atggaatatt gattcctgtc
     1741 acagctaatc cgtagattcc tgcgcctaaa atgattccgc acaattctgt aaataaattt
     1801 aattttttca tttctagcct cttttctttt gaaaattttc agcaacttct ttattatact
     1861 gacttatact cttacttcaa gaggaaaatg aaaaaaaatt atttttggct gtttcttttt
     1921 atttatcaaa taaggagtgg aaaaatgcga gcagcagact tattgacaat tcttacaaaa
     1981 tcacccaaaa aaacagagta tcaaggagtt tttttggctc aagaacaaaa actggtgcct
     2041 gtgacaatgg tccagataaa taaagcaaat caatttatct ttttatttga acacggcaaa
     2101 gcaccacttg ctatgaaaga catctttctt tttttgatga agaaccgtga gaaagctgtt
     2161 tattatcagt caaaagaaga actcattcct ctttatggag tgaaagagat agaaaataaa
     2221 gtggtgatat aagtaaaaat aagaaaacaa gacgtttatg atgtcaaaac aaccattttt
     2281 tacatttttg gcaaaaaagt gtcatgatac agtataatat tcgttgaaca ggccaataaa
     2341 ggtgttctcc cccacgagat ttctacttta ttggctgttt ctttttatta aaataaaagt
     2401 tgtgtgtgta aaaaagatat agctgattcc aagtgacaat ttcgtataga tttttatggt
     2461 attcgtagtg aaaaaacgag aaccaaaaag ttgatccgac tttgttgctt ggattctttt
     2521 tttgtcagca tatttagagg tatttttttc ttttttttgt tcgtgctgta aggttaaggc
     2581 aagacaagtt agttgggaaa aaggaaagaa atgtttatac ttaaagaata acagaaagga
     2641 aggtcgcatg aataatttta tacaaacatt aagtgaaaga aaaggcgagt tgctggaagc
     2701 tgcatttcaa catctgtcca tttctctcat ttctttgctg attgcagcac tgattgctat
     2761 tcctttagcg atttgggcag ccaatcataa aaaaatggca gaagtcttat tgcagatcac
     2821 gggtgtgctc caaacgattc cttcacttgc cttattaggt ttacttatcc catttgtagg
     2881 gatcggaact gttccagcat tgattgcact tgttatttac gctttgcttc cgattttcca
     2941 aaacacgtat attggtctag ctgaaattga cccgtctatt gaagaagcag cggtagcatt
     3001 tggtatgtcc agaatgagac gcttgctgaa agtagagctt cccatcgcat tacctgtcat
     3061 tatctcaggt atccgaactg ccttagtttt aatcatcggt acggctactt tggcagcatt
     3121 gatcggagca ggtggattag ggacatttat tttgttaggt attgaccgaa atacacctgt
     3181 tttgacattg attggtgcga tcagttctgc cttgcttgca attatattca gcggactgat
     3241 tcgctggttg cagcataaga aacctcgata ttccatcatt actttagcag cagtggtgtg
     3301 tttatttggc ggcgtttctt tatatcagtc tgccttgttt aaaaatgaaa ccatcacgat
     3361 tgctggaaaa ttaggagcgg aacctgaaat cctgatccaa atgtataaag aattgattga
     3421 agacaacaca aaaacagaag ttgaattaaa accgaatttt ggcaagacga gttttttgtt
     3481 caatgcactg gatcaaggtc aaatcgatat ctatcctgag ttcacaagta ctgtcctaga
     3541 aagcttggtg aaggtacctg aagcaatgaa aagtgctgat ttgacaaaag aaaaaacata
     3601 tgacgaagca gaagaattat tgaataagca attcgatatg acattattaa aaccaatggc
     3661 ttaccaaaat acgtatgcct tggcagtcaa gagatctttt gcgaacgaac atcaacttaa
     3721 aaagatttcc gatttggcag ctatctctga tcagatcaaa gcgggattca cactggaatt
     3781 tattgatcgt tcagatggat ataaaggaat ccaagaagca tatggcttga atttttcaag
     3841 tgtacaaagc atggagccaa gtttgcgtta ccaagcaatc aataatggag atgtcaatat
     3901 tgtggatgcc tattccacag atagccagct caaggagtac gatctagtga ctctagaaga
     3961 tgatcgaggg ttattcccag cttatcaagg cgcaccgctg atgaaaaaag attttgctaa
     4021 agaacatcct gaaatcgtta aagcactgaa taaattaagc ggaaaaataa cagaggatca
     4081 aatgattgat atgaattacc aagtcaatgt cgaaaagaaa aagccgacag aagtagcacg
     4141 aatcttcctg aaaaatgaag gattagtaaa ggaggaagat cagtgactaa attaatcgag
     4201 ttcaaacatg tgcaaaaaaa gtatgatgga aagtatgtca tcgatgacct aaatctggca
     4261 atcaaaaaag gagaaatctt tgttttggtt ggtccttccg gtagtggaaa aacaactact
     4321 ttgaaaatga tcaatggatt atctaaacca tcagcaggag acatctactt caaaggaaaa
     4381 tcgttaaatg aatataatct gcagaaaatg cggtggaata tgggatatgt gctgcagcaa
     4441 atcgctttgt tcccgaccat gacagtcaag caaaatattg aagtcatccc tgaaatgtta
     4501 ggttgggaaa agcagaaaag agcagaccgt gtagatgaac ttcttcaaaa agttggctta
     4561 tctcctgata tttatcgaga tcgtatgcct agagagttgt ctggaggaga acagcaacgg
     4621 atcgggatca tccgagctat tgctgcaagc ccagatgtga ttttgatgga cgagccattt
     4681 agcgcattag atccgatttc aagaaactca ttacaagaat tggttttgtc cttacacgaa
     4741 gaattgggca cgaccatcgt tttcgttacg cacaatatgg aagaagcaat caagctaggt
     4801 gatcgtattg catttatgaa ggatggagaa attatccaat gtgacacacc agagcagtta
     4861 ttgatgaatc ctaaaaacga ctacgttcgg catttctttg atgaaccgaa acagacgaaa
     4921 gagtggcgag tagaagattt agtcgtcaat ggatatttct taaatgaaat accagaaaat
     4981 gctcgtcaac aagtttgctt tgatacgcct atgaaagaag tatattcgct tctttcggtg
     5041 tatccaagca ttgtgatagt agaaaagcaa agaagtattg ggtcgctgac aagtaaagaa
     5101 atctttgctt ttttaagtcg agaggaggaa ggaaatgaaa acatatgatg caatcatcat
     5161 cggttcaggt gtgagcggct taagtgctgc ttatggattg aaagaagcag gtaaaacagt
     5221 actagtggtc gaagaagatc tatggggcgg gacttgtcct aaccgtggat gtgatcctaa
     5281 aaaagtcttg ttaagtgcag tagaggcacg taatcgggta aaacaattga gtggaaaagg
     5341 ttttaacgag atcccaactg ccaactggga agaacttcaa aaattcaaac gaacatttac
     5401 ggatccagtc ccagaaagcc gaaaaaaaca attagcagaa gctgaaatcg atcatctttc
     5461 aggaaccgct cgttttttgg atgattcatc tattgaagtc aacgaagaag tcttccatgc
     5521 ggattactta gttttggcaa ccgggcaaag acctacgatc ttaccagtgg agggaaagga
     5581 atacttgaaa actagtgcag actttttatc attgcctgta ctgcctaaag aaatcatttt
     5641 tatcggtggt ggttatattg cttttgagct agctacgatt gccaatgctg cagggagcaa
     5701 agtaaccatt gtccatcata atcaacggcc attaaaagaa tttgaggcgt ctttggtaga
     5761 ggaagccgtc catcaaatgg aagcatctgg cattcagttt gcttttggtg ttgaaaccca
     5821 aaagatcatt tcagaaggta ctcgctatcg tttagtcgga aaagagacgg aattagtagc
     5881 agatatgatt ttttgtgcga ctgggagaca gccgaataca gaatctttag cacttgagca
     5941 agcgaatatc gtctttgata aacacggaat tgcagtcaat gattatctgc aaacgagcaa
     6001 tccaaaaatt tttgcgtgtg gagatattgt ttcaaggaaa accccaaaat tgacaccagt
     6061 cgccactttt gaaggaaatt atgtagctaa gcggataacg gatgcaacaa gcgaacctat
     6121 caaatatccg attataccta cgatcgtcta cgccagtcct aaacttgctg aagtaggagt
     6181 tacaaaaagt cacgcctctt cgtcagatca agtggtagag atggatctta ccagttggtt
     6241 cacctatcat cgtgtcaatg aaccagttgc taaggctgaa ttgacctttg accagcaaaa
     6301 ttatttgatt ggtgctgcag tgattagcga gcaagcagac gaattgatcg atgatttgac
     6361 actcgtcatc aatcaaaaat tgactaaaaa agagttggat agctatatca tggggtatcc
     6421 gacattggca agtgatctct cctatttatt gaaataatca gcatgataac taaagcgctt
     6481 gttgcttttt ccttcttgtg ctacacttta aaaaatgaat acctgtttct ggggatgtcg
     6541 tagacgacat gagagtaagt tgtgaactta gacccattga acctgtcagt taatactggt
     6601 gaagggagaa acatagcaga cgcttgaagc gggttactat gtcgtgccca tttcaagcgt
     6661 tttttgttat tcatattaga agaaaggagg taacaaaatg aagaaaaatc tttatccagc
     6721 agtcagtatg gcattcattt taattatttg gcagattgtt gtcatagttt ggaaaatacc
     6781 tgcctttatt ttacccggac ctgctgctgt attttctgca ttagcggcag atgcacaagt
     6841 attactttcc cattctgtca cgacattaaa tgaagcagtg cttggtttgg taatagctag
     6901 cgttctttct tttattactg ccttggcaat ggattattgg aagtttttag aaatgtcttt
     6961 ttatccgtta ctagtgattt cacaaatgtt gccaatcatg gtgttagggc cattacttac
     7021 cctatggttt ggtttcggta tgcttccaaa agtgatcctt gttgtcttga taagctattt
     7081 tccgatcgta gtttcttttt cggatacatt gaggaaagta tcaaaagagc aaatcatctt
     7141 tttgaaaacg atgggggcag atacagggaa gatttatcga atatataaaa taccagcggg
     7201 tttatccggc ttcttttccg gtttaaaagt ggctgctact tattgtgtca gcggagcagt
     7261 cgttggagaa tggctaagcg ctcaagcagg cttagggtat tacatgatac gcgtaaaaaa
     7321 cagctaccag atcgataaag tttttgctgc gatcatttgt gtcattctat tgagtttatt
     7381 gctgaatggc gcttgttcat tattgaaaaa agggtattat cgtatgcttt atatttttta
     7441 agagaagggg atcaaatgaa aaaattatgg cttttattac cgctactgtt gcttttatcc
     7501 gcttgtggca ctgcaaaaga aacaagtagc aaacaagaaa taaaggattt gaaaaaagtg
     7561 acacttgttt tggattatgt accgaatact aatcatactg gcatctacct agcaaaagaa
     7621 aaaggctatt ataaagaggc tggtttaaat gtccaaatca tcgaaccagg agataattcg
     7681 acaagtattg gtctagtagg tgcggacaaa gcacaatttg gtgtaagtta tcaagaagat
     7741 gtcacttatg ctcacgcaga tggacagaat ataccagtca aagcaattgc tacagtgatc
     7801 aaacataata cttctggatt cgccacccta tcagacagta acatccattc accaaaagat
     7861 tttgaaggaa aaacatatgc aggttggcaa agtccaagtg aagaagctgt cttaaaagct
     7921 gtgatggaaa aagacggcgg ggacttttca aaactgacaa tggtaggaag caatggagaa
     7981 gggccagaaa gcttaggaaa atcctcagat atccaatggt actttgaagg ttgggatatg
     8041 atcaaagcaa aagaagcggg tattgaacta aactatatcc cattgaaaga attagatgaa
     8101 cggttagatt actatactcc ggtaattatt acgaatgatc aactgatcaa aagtgatcca
     8161 gaattggtac agtcttttat ggatgccacg aaaaaaggct atcaggaagc tattaaggat
     8221 ccaaatgaca gtgctaaact gttgcaaaaa tatgcaaaag aaaatgatcg gacgttttta
     8281 gaagaatcac aagcattctt gtcaaaaaat tatacggatg atcctgagaa ttggggattg
     8341 atggaagaaa aagtttggcg caattataca gcttttatgc aggaaaacgg attgatcaag
     8401 caagatgtac cttcgcaaga actattcact aatcagttta taaaatagga gtgatagata
     8461 tgtcaatcca aatcagccac ttgaatgtag tcattgaaaa cctgaaaata ttagaagaca
     8521 tccatttcac tatccctaaa gataccttta catcgattgt cgcgccaagc ggagccggta
     8581 agtcaacatt gctgaaaact ttaacaggag tccagcctat gacttctgga acgatcaaag
     8641 tagacgatca aaaagtaact ggtctccata cagcatttag ttatatgccg caagaagata
     8701 tgttacttcc ttggctgagc gtctatcaaa acgttacgtt atatcaaaaa atcaatcatc
     8761 taacaatcaa tgaagaacaa gtaagggatt atctggatat ctttgggtta aacggctatg
     8821 aacatttttt gccggaacaa ttatctggcg ggatgaagca gcgaacggcc ttgttacgaa
     8881 caatcatgaa tccttcttct tacttgcttc ttgatgaacc atttggagcg ttagatgcta
     8941 tgaccagagg gcagatgcaa gactggatgt tgaagctgcc taaaaaagca aagcggacta
     9001 ctttacttgt gacgcatgat atcgaagaag caatttattt atcagacagg attcttgtgc
     9061 tttccgcccg tccggcacat gtgattgctg agattcaagt gcctgaaaaa cgacggtcac
     9121 gtgaatggct actgcagcaa tcagagttga agcaaacgat ttatcagtta ttggcaggtg
     9181 aattagatgt taagtgatgc tcattgtcat ttagatggga gtcagagttt agcactcctt
     9241 cagcaggaac acacgatttt gacgatcatc aattgtgatt cgccagaaga atggaaggaa
     9301 aacagacagc ttgcagcaag taagactcaa gccttaagtt acggtatcca tccttggaaa
     9361 gcagatagct atacgtttga acaagttgag ccttttttga aaaaagcaag gatcatcggt
     9421 gaaatagggt tagataatat ttggacgaat gtaccgatga ctacacaaaa aaaagtattt
     9481 gagcgacagc ttgcttttgc agccataaat gagaaacctg ttgtactgca cacaaaagga
     9541 tgcgaaaaag agatcttaaa ttatatccaa gcttacccta atcactattt gatccattgg
     9601 tattcttctt tggactatca acaagactat attgatttag gctgttattt cagcattggt
     9661 cttgatttga aaaagaatcc agcagtctgg caactagcta aagcagtccc aatcgaccac
     9721 ttacttattg aaacggatgg actacatgca gcagagtggg ctttaggggg gattttttca
     9781 gaaaaagatt atgtctcact gcttgaagaa cagttaaaga caatcgctga gatcaaagag
     9841 ctatcagttg aagaagttaa aaaaaatact tatcaaaact tggaacgttt cattagatta
     9901 ggtaaataaa aaagagatgt gacacaacta gtgtcgcacc tctttttggc tttctttgta
     9961 taaaagtaaa ctgtttgatt aataaatgaa tcttagtacc aaccgtttgc ttcccagaat
    10021 gctttcgccg cttcccaaga accataacgt gaagtaacat attgttctgc tactctttct
    10081 tggtttgcag cagagtagtc accatttaag taagaagaat ctaattggta acgtccgatg
    10141 taacgtccgt tcgttgctgt gtaagaaccg cttgattctt tttgtgcgat ccattctttt
    10201 gcagagcttg tgcttgctgg agtagcagca gtttctgtta cagcaggagc aggttgtgtt
    10261 tcagcaacag gcgctgcttg tttttccgtt tgaaccgttt cttgtacaac aggttgttca
    10321 gcttggactg gtgcttcttg aacggctgct tgaggttcag cagctgcttg tgcagagcct
    10381 tctgttggga ttgttaattg ttgtcctgag ta
//
LOCUS       DAXLPC010000091        10217 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.092, whole genome shotgun sequence.
ACCESSION   DAXLPC010000091 DAXLPC010000000
VERSION     DAXLPC010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.092"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(47..808)
                     /locus_tag="ACF3UE_002273"
     CDS             complement(47..808)
                     /locus_tag="ACF3UE_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFD3635644.1"
                     /translation="MHTPEEIMELSIHLGTKKIHKPILAKLILGFIGGAMISLGYLAY
                     VRVSASIPESMASLTSLVGASVFPIGLLVILLGGGELITGNMMAVAIAFMDKKVTFSQ
                     LVKNWSVITFANIIGAIFVAYFFGHFVGLTHSGVYLDQVIHIADHKIAVSWWQALGSG
                     IGCNWFVGLALWLSYGAKDAAGKVLTIWFPVMIFVAIGFQHSVANCFVIPAAIFEGQA
                     TWLEFLSNFIPVYIGNIIGGAIFVSGFYYVSYKHH"
     gene            1128..1373
                     /locus_tag="ACF3UE_002274"
     CDS             1128..1373
                     /locus_tag="ACF3UE_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635645.1"
                     /translation="MSKSKKNITIIGLGLTVYLFTEFVYRHVNLFAEPLFVLYESNSS
                     IVSELANLMIALLFTPALRVITILVCLVLLFFVNKKK"
     gene            complement(1557..2306)
                     /locus_tag="ACF3UE_002275"
     CDS             complement(1557..2306)
                     /locus_tag="ACF3UE_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3635646.1"
                     /translation="MLKLERHQKILDLLNAEQKVIASDLSQRFNVSEDTIRRDLKDLD
                     SQGLLKRVHSGALRVGPPITNFNYRETVASEQKTALAHKALPFLKEESVIIIDGSTTN
                     LALAKEIPQDFRATIITNSPPIAIALAQHPNLEIINIGGTFYKQSMINIGVQAYKQLQ
                     NIRADLYIMGIYNIDLDVGTSVPTMQESDIKREMIRISTEVLGMITNDKFGTISNHIV
                     GPIEDLTYLISEEIPEKVRKEYNKQKIVLID"
     gene            2492..3196
                     /locus_tag="ACF3UE_002276"
     CDS             2492..3196
                     /locus_tag="ACF3UE_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFD3635647.1"
                     /translation="MEKKIILSPSLMCGDLANLEGSIQELESIGMDSLHIDVIDGSFS
                     PSMPLGIETIKRIREITSMNFDVHIMAKDNDNEFFIGEMLKIGVESITFHYETSLHID
                     RYIQLIKNSGTKVGIALNPATPLNVLQYILPEIDRICLMLINPGFATNKSEKQVSYAL
                     KKITDLCQLVNEKELAVDIQVDGRVSLETIPGLLDAGATNLVLGSTSLFLKGNTLAEN
                     QKLLYQAMKQSVRKNQ"
     gene            3236..3793
                     /gene="hxlB"
                     /locus_tag="ACF3UE_002277"
     CDS             3236..3793
                     /gene="hxlB"
                     /locus_tag="ACF3UE_002277"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HFD3635648.1"
                     /translation="MSYKAAKQNIVREITETLDRISSKDVEQLIKKIEKAERVFFVGV
                     GRVLLALEGMAKRLGHLGIQTVVVGQITEPAITDKDLLIVGSGSGESAFPLTIAKKAK
                     EFGSQVAHIGSNPDSTMKEYSDLFIRIPVQTKLALPEEISSIQPMTSLFEQSVLLLGD
                     SIALVMIEEKAIDMSKLWQYHANLE"
     gene            3801..4940
                     /locus_tag="ACF3UE_002278"
     CDS             3801..4940
                     /locus_tag="ACF3UE_002278"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008926 - mannitol-1-phosphate
                     5-dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0019594 - mannitol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFD3635649.1"
                     /translation="MKAVHFGAGNIGRGLIGQILHQNGFDLCFIDTNPELIHQLNQDK
                     GYTIEIIDEMNRSDFIDHVVALNSLSELEEVITATKNADILTTSVGAINLVKIAPIIA
                     QALSKRFEQKHSINIVANENVINASDVLKKEIYSLLSEKEQENFDEYAYFVNTAIDRQ
                     SLGKVLGGKMISVVEPYYEWIMDRQQLDPTTSFDMKNVNLVDDMEPYIERKLYIVNAA
                     HAAVAYLGALKGYKTIQEAIQNMEIFNLVKQFLMENIEYFVQKYHFSREELTSFVEKT
                     LNRHGNQKLSDEITRVGSSPIRKLGPNDRLIAPIVKLDSYHLPYDAGIKVIAAGYHYR
                     NLADPEAEQLRRMIVNDGLKATIKKISRLEGKLLNEVVAAYESQI"
     gene            4952..5383
                     /locus_tag="ACF3UE_002279"
     CDS             4952..5383
                     /locus_tag="ACF3UE_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3635650.1"
                     /translation="MLKEQLSGNTMFMDAIDSWQEAIRVSARPLIGKGIIEESYVQAM
                     IQNVLDNGNYIILLPLVAMPHARPEFGSKGVGMSFLCLDKPVMFPSEEPVKFFFTFSS
                     DSPKGHLDLMANLGELLSDEKMYQKLFDVKTEKALLDLIKK"
     gene            5397..6842
                     /locus_tag="ACF3UE_002280"
     CDS             5397..6842
                     /locus_tag="ACF3UE_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HFD3635651.1"
                     /translation="MEVANKKKRVSMRAKVQAIGGFLTNMVLPNIGAFIAWGIVTALF
                     IPTGWFPNESLNELVSPTVSYLLPLLLAYTGGRMVGGTRGAVLGTIGTIGLIIGADIP
                     MFMGAMIMGPLGGWMMKKTDDFLDGKVPAGFEMVVNNFSIGIIGFILMCLSYLVVGPI
                     IQSANQFVTSAIEALVSTGFLPILSLINEPAKVLFLNNVIDQGVYYPLGMQQTLEAGR
                     SIYFMVASNPGPGLGLLLAYSLFGKKAAKQTAPGAIIIHFFGGIHEIYFPYVLMKPLT
                     ILSMIAGGMTGIITFELFDAGLVAGPSPGSIFSYLALTPRGNFLGVMAGVVTATLVSF
                     FVTSVILKADKSTDEDRNFELSVQKSKTMKSEGRKLLKEENAREICTEKKEMNKISFA
                     CDAGMGSSAMGATIFKKKLQKAGITDVEIKNYRIEEVPEDSDLVIVHQDLEERTRKAH
                     PNMKIVTLKNYLQDPVINGLAEEIIGLKTED"
     gene            7128..8753
                     /locus_tag="ACF3UE_002281"
     CDS             7128..8753
                     /locus_tag="ACF3UE_002281"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFD3635652.1"
                     /translation="MKKIYSKEIDCFRGIAVLAVIFYHLPNSLLPGGLQGVTIFFVVS
                     GFLMAKNTIRDEKNRQFSFLHFYYKRIKRIYPFLLFSLVVFIFILGISNIRLIGNIRS
                     ELPSLIFGYNNWWQLNQGVSYFDSYFNASLFKHYWSLSVELQFYLIWPFLFIVIKRMR
                     RKQVFYLIYTLIFVSILFSLFLPSTKAYYHTIAKLFPFLLGVWGYFNRITIGRFFEQN
                     TFSKIWLLLLASLCLILFPIFPYTLNELLISICFALLLASVDDMNIAKKTKIASTKLS
                     FVGKISYELYLVHFPVLIALTNLFKHHHWKYLDIAGLFTVFLCTLLMITCFRKGVQKM
                     RSPKIWTAMALMIIGVSVLVLRAPASRLTADQNQLQSLLKENSSKANAGENLLSQEKK
                     ILFIGDSVMLGAYQELKETFKKEALVDAKESRQITALPEILKEHKDLVSYQQIVIGLG
                     TNGVITDEAIEQTMSLLKDKKVYWVNIKAPTGWQDTINATLATLPNQYSNITMIDWYS
                     ESKNHPEFFYDDETHLNESGRTAYAKYIASVIQ"
     gene            9385..9738
                     /locus_tag="ACF3UE_002282"
     CDS             9385..9738
                     /locus_tag="ACF3UE_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635653.1"
                     /translation="MNSFKKKFVSRFLNMKNFFEKKGDYDAYNYVLNLEKQTYYTLRK
                     NDDNDFWTMLPKMLSIDSKLSLLEEFINLDIEEFCGGKELINMVESDYHTYYKESCGY
                     KVDEQCPQSIIFYIE"
BASE COUNT         3553 a         1487 c         1954 g         3223 t
ORIGIN      
        1 tataaagaga ttgaaggtaa tgctcgaatg aacattacct tcaatcttaa tgatgcttat
       61 aactaacgta ataaaaacct gaaacaaaaa tagctccgcc gatgatattt ccaatataaa
      121 cggggataaa attcgagaga aattctaacc aagtcgcttg accttcaaat atggcagcag
      181 gtatcacaaa acagttggcc acactatgct ggaaaccgat tgccacaaaa atcatgactg
      241 gaaaccaaat cgttagtact ttgccggccg catcttttgc tccatatgat aaccataacg
      301 ctaaaccgac aaaccaatta caacctattc cggagcctaa tgcttgccac caagaaacag
      361 cgattttatg atcagcaata tgaatcactt ggtcgagata gacacctgaa tgagttaaac
      421 caacaaagtg tccaaagaaa taggcaacga aaattgcacc aataatattt gcaaaagtaa
      481 tcactgacca attcttaacc agctgtgaga atgtgacttt tttatccata aaggcaatcg
      541 ccacagccat catatttccg gtgatcaatt caccaccgcc aagaaggatg accagcaggc
      601 cgataggaaa aaccgaggca ccaactaaac tagtcaagct agccatagat tctgggatag
      661 aagcagagac tcgtacgtat gccaaataac ctagagaaat catggctcct ccgataaaac
      721 ctaaaatcag tttagctaag ataggtttat gtattttttt tgttccaaga tgaatactga
      781 gttccataat ttcttctggt gtgtgcataa tacttcgatt cctactttct taatgaattt
      841 tcatgtgata aaatatagtg aaaaaaatca cattttcttt gttgattata tcatcttatt
      901 atttatatgt gcatattatt gtaaaatttt ctatttaatc acatttgatt ctaaaaaaga
      961 aacaaaaata aaagtcatgt atatggtggt caaaaagtaa ataatatcag ttatcaaatt
     1021 tcctgtaaat tttcttgaaa ctacagcata ttattacttc aaaacaatct acatttttta
     1081 taaaaaagga aatgaataac tgaaaaaatt attataggag agaaaaaatg tcaaaatcta
     1141 aaaaaaatat caccataatt ggtttaggct taaccgtata tttatttaca gaatttgttt
     1201 atagacatgt gaatttattt gcagaacctt tatttgtatt atacgaatca aattcctcaa
     1261 tcgtcagtga acttgctaat ttaatgatag cattgctgtt tactcccgcg ttgagagtca
     1321 taactatttt ggtctgttta gtgctattgt tttttgttaa taaaaagaaa taacgtagta
     1381 tttcaaaaga caaagaagtg ggatgatgat tgctatagta tgttatacgt ggtgctaggt
     1441 aagtgagaat aaacaaaaaa ggaaacacgc aataaagttt atttcaaaac tttattgcgt
     1501 gtttcttttt tagatttttt atatctgttg ctttagtagt taccaatagt tttcgcttaa
     1561 tcaatcaaaa cgattttttg tttattgtat tctttacgaa ccttttcagg aatttcttct
     1621 gaaataagat aggtaaggtc ttcaattgga ccgacgatat gattactgat ggtgccgaat
     1681 ttatcattag ttatcatccc aagtacttca gtagaaatac gtatcatctc acgtttaatg
     1741 tcggattctt gcatagttgg cacgctcgtt ccaacatcta gatctatgtt ataaataccc
     1801 ataatataaa ggtcggctcg aatgttttgt agttgcttat aagcttgtac cccaatattg
     1861 atcatagatt gtttataaaa agtaccgcca atattgataa tttccaaatt aggatgctgt
     1921 gctaatgcta tggcaatcgg cgggctattg gtaatgattg ttgcacgaaa atcttgtggg
     1981 atttcttttg ctaaagccaa gttagttgta cttccatcaa tgatgatgac agattcttct
     2041 tttaaaaaag ggagggcttt atgagctaat gcagtttttt gttcgctagc tacagtttct
     2101 cggtagttaa aattggtaat tggcggacca acacgtaaag cgccgctgtg tactcttttt
     2161 aagagacctt ggctatccaa atctttcaaa tctcgtcgaa tcgtgtcttc ggatacattg
     2221 aaacgttgac ttaaatcact agcgataact ttttgttctg cgtttaataa atctagaatt
     2281 ttttgatgac gttctaattt caacatgttg cgtgctcctt cttatttatt cttgtttatc
     2341 atgtcattta tgcgttttta tgtcaataat ttccgttttt aatacactaa aaaggcataa
     2401 acaagcaaaa acaaaatatt tttatgcagt tttatgttga ctagtatttg ttaagcggtt
     2461 acaatgaggg ggtaattaaa ggagggaatg tatggagaaa aaaattattt tgtcgccttc
     2521 acttatgtgt ggggatctag caaatttgga aggaagcatc caagaactag aaagtattgg
     2581 gatggattcc ttgcatattg acgtgattga cggttctttt agtcccagta tgcctttagg
     2641 gatcgaaaca atcaaaagaa ttagagaaat cacttcaatg aattttgatg tacacatcat
     2701 ggctaaggat aacgataacg aattttttat tggagaaatg ttgaaaattg gcgtagagag
     2761 cattactttt cattatgaaa caagcctcca tattgatcga tatatccagc tcatcaagaa
     2821 ttctggaaca aaagtaggga tagctttgaa tccagcaact ccgttaaatg tattacaata
     2881 tattttaccc gagattgata ggatttgttt gatgctgatt aatccaggtt ttgcaacaaa
     2941 caagtcagaa aaacaagttt cttacgcgct aaaaaaaatt acagatcttt gccagttagt
     3001 aaatgagaaa gagttagcag tagatatcca agtggatgga cgggtatcgt tagaaacgat
     3061 cccgggatta ttagatgcag gcgcaacaaa tctggtatta ggaagtacaa gtttgtttct
     3121 taaaggaaat acattagcag aaaatcaaaa actactttat caagcgatga agcaatcagt
     3181 taggaaaaat caatagatgt agtggtcctg aataatagaa atggagggga aatagttgag
     3241 ttataaggcg gcgaaacaaa atattgtaag agaaattact gaaacattag accgtatttc
     3301 ttcaaaagat gtggaacaat tgataaagaa aattgaaaaa gcggaacgag tttttttcgt
     3361 gggggttggc agagtactgt tagcgctaga aggaatggca aaacgcttag ggcatctagg
     3421 aattcagaca gtagtcgtag gacaaatcac tgaaccggca attacagata aagatttatt
     3481 gattgttggt tctggtagtg gggaaagtgc tttcccacta actattgcaa aaaaagcaaa
     3541 ggaatttggg tcccaagttg cccatatagg atcaaaccca gacagcacaa tgaaagaata
     3601 ttcagatctt tttattcgta tacccgtaca aacaaaatta gcgttaccag aggaaatttc
     3661 ttctatacag ccaatgacta gcctgtttga acaaagtgtt cttttgttag gagatagtat
     3721 tgctttagtg atgatagaag aaaaagcaat tgatatgtca aagttgtggc aataccatgc
     3781 taacttagag taggtgaaaa atgaaagcgg tacattttgg agcagggaac atcggcagag
     3841 ggcttattgg acaaattcta catcagaatg gattcgatct atgttttatt gatacgaatc
     3901 ctgaactgat ccatcaatta aatcaagata agggttatac tatcgaaatt attgatgaaa
     3961 tgaacaggag tgatttcatt gatcatgttg tggcactgaa tagtttatcc gagctagaag
     4021 aggtgattac agcaacaaaa aatgcagata tcttaacaac atctgttggc gcaataaatt
     4081 tagtaaaaat tgcaccgatc attgcgcaag ccttaagtaa gcgatttgaa caaaagcata
     4141 gcatcaatat cgtagctaat gaaaatgtga taaatgcaag tgatgtgttg aaaaaagaaa
     4201 tttattcttt gctgtcagaa aaagaacaag agaattttga tgaatatgca tattttgtga
     4261 atacggcaat cgatcgacaa tctttaggaa aagttcttgg aggaaaaatg atctctgttg
     4321 tcgaacctta ttatgaatgg ataatggatc gacagcagtt agatccaact acatcttttg
     4381 atatgaaaaa tgtaaatttg gttgatgata tggagcctta cattgagcga aagctttata
     4441 tcgttaatgc tgctcatgcg gcagtagctt atttaggcgc actgaaagga tataagacga
     4501 ttcaagaagc aatccaaaat atggagattt tcaatctagt caagcaattt ttaatggaga
     4561 atatagagta ctttgtacaa aaatatcatt tttctagaga agaattaaca tcttttgtgg
     4621 aaaaaacatt aaaccgtcat gggaatcaga aactctccga tgaaattact cgtgtaggaa
     4681 gttcccctat tcgaaaatta ggccctaatg atcgtttaat tgctcccata gtaaaactag
     4741 attcatatca tttaccttac gatgcaggaa taaaagtaat tgctgcggga tatcattatc
     4801 ggaatcttgc tgatccagaa gctgaacaac tacgtcgaat gattgtaaat gatgggttga
     4861 aagcaacgat taaaaagatt tctcgtttgg aaggtaagct gctgaatgaa gttgtcgctg
     4921 cttatgagtc ccagatttag aggaggagaa tatgctaaaa gaacaattgt caggaaatac
     4981 aatgtttatg gatgcgatcg attcatggca agaggcaatc cgagtaagtg cgcgtccttt
     5041 gataggaaag ggaataatag aggaaagcta tgtacaagcg atgatacaaa atgtgttgga
     5101 taacggaaat tatattatat tactgccact agtagcaatg cctcatgcgc gtccagaatt
     5161 tgggagcaaa ggggtcggga tgagcttttt atgtttagat aagccagtca tgttcccaag
     5221 tgaagaacca gtaaaattct tctttacctt ttcttctgat tcgccaaagg gacatttaga
     5281 cttaatggcc aatcttggag aattgctgag tgatgaaaaa atgtatcaaa aattattcga
     5341 tgtgaagaca gaaaaagcat tgttagattt gataaagaag taaaggagag aagaaaatgg
     5401 aggtagcaaa caaaaaaaaa cgagtctcca tgcgagctaa agttcaagcg attggcggtt
     5461 tcttaacaaa tatggtattg ccaaatatag gcgcatttat tgcatgggga attgttactg
     5521 cattattcat tccaactggg tggttcccaa atgaatctct gaatgaactc gtaagtccga
     5581 cagtcagcta tctattgccg ttactacttg cctatactgg tggtcggatg gttggtggta
     5641 cacgtggagc tgttttaggt acaatcggaa caataggttt gattattggt gctgacatac
     5701 caatgttcat gggagcaatg attatggggc cacttggtgg gtggatgatg aaaaaaacag
     5761 atgatttttt agatgggaaa gttcctgctg gttttgaaat ggtcgtcaat aatttttcta
     5821 taggaattat tggtttcata ctgatgtgcc tttcttatct ggtagttgga ccaataatcc
     5881 aatcagctaa tcaatttgta acgagtgcaa ttgaagcatt agtttcaact ggttttttac
     5941 cgatactgtc cttaatcaac gaaccggcaa aagtcttatt tttaaataat gttattgacc
     6001 aaggtgttta ttatccatta ggtatgcaac aaacattaga ggcaggcaga tcaatttatt
     6061 tcatggtagc atcaaatcct ggccctggct taggactatt gttagcttat tctttatttg
     6121 gtaaaaaggc agcaaaacag acagcaccag gtgcaatcat catccatttt ttcggcggaa
     6181 tacatgagat ttattttcca tatgtattaa tgaaaccact cactatatta tctatgattg
     6241 ctggtggaat gacaggaatc atcacttttg aattatttga tgcgggcctg gtagcaggtc
     6301 caagtccagg ttctattttt tcttatttag ctctaacgcc tcggggaaat tttttgggtg
     6361 tcatggcggg agtggtcaca gcaacactgg tttccttttt tgtaacatca gtaattttaa
     6421 aagcagataa atcaacagat gaagacagaa attttgaact atcagttcaa aaatcgaaaa
     6481 cgatgaaatc agaaggaaga aaattattaa aagaagaaaa tgctagagaa atatgtaccg
     6541 agaaaaaaga gatgaataaa atttcctttg cttgtgatgc aggaatggga agcagcgcaa
     6601 tgggcgcaac aatattcaag aaaaaattgc aaaaagcagg tattactgat gttgagataa
     6661 aaaattatcg aattgaagag gtaccagaag atagtgattt ggtgatcgta catcaagatt
     6721 tggaggaacg gactagaaaa gcacatccta acatgaaaat tgtgacatta aagaattatt
     6781 tgcaagatcc agtaatcaat ggattagcag aagaaatcat tggattaaaa acagaagact
     6841 aatttatggg aatttttgat taacctttat taaaattatt ttgcctaata taaaaaggtt
     6901 gtgacatggc ttgtgtcgca accttttttt gtcgcacaaa taattaatcg gatattttat
     6961 gttcatattt tttgtgatca acgagaactg atggggcaaa gatacatttt agatactttt
     7021 aactgttaat ttacaaaaca aggtgaaacg aatagaaaaa tgaaaaaatc gatacggaag
     7081 aatatgtttg attaaaacat gcatgaagag aaggaggttg atgatacatg aaaaaaatat
     7141 attcaaagga aatcgattgt tttagaggca ttgctgtttt agcagtgata ttttatcatt
     7201 tgccaaatag tttgctgcca ggcggattgc aaggagtaac gatctttttt gtggtttctg
     7261 gttttttaat ggctaaaaat acgataagag atgaaaaaaa cagacaattc agttttttac
     7321 atttttacta taagcgtatc aaacgtattt atccattttt actgttttct ttggtcgtat
     7381 tcattttcat actagggatt agcaacattc gattgatagg aaacattcgt agtgagctac
     7441 ccagtttgat ttttggctat aacaattggt ggcagctgaa tcaaggagta tcttattttg
     7501 actcttactt taatgcttct ttatttaaac attattggtc gctttcagtt gaactacaat
     7561 tctatttgat atggccattt ttgtttattg tcattaagcg tatgagaaga aaacaagtgt
     7621 tttacttaat ctatacattg atttttgttt ctattctttt tagtttgttt ttaccttcaa
     7681 ctaaggcata ttatcatacg atagctaaac tttttccatt tttattagga gtttgggggt
     7741 attttaatcg aataactatt ggccgtttct ttgaacaaaa cacttttagt aaaatctggc
     7801 ttttattact agctagtctt tgtctgattc tgttcccgat ttttccttat acactaaatg
     7861 aactactgat cagtatttgt tttgctctat tgttagccag tgtcgatgat atgaacattg
     7921 caaaaaagac caaaatcgct agtacaaaac tttcttttgt aggaaaaatc agttatgaac
     7981 tttatttggt gcatttccca gtattgattg ctctgacaaa tctattcaaa catcaccatt
     8041 ggaaatattt ggatatcgca ggtctattca ctgtgttttt atgtacatta ctcatgatta
     8101 cttgctttag aaaaggagtg caaaagatga gatcacccaa aatttggaca gctatggcac
     8161 taatgataat cggagtttct gtactggtat tacgtgctcc tgccagtcga ctgaccgctg
     8221 accaaaatca gttgcaaagt ttattaaaag aaaactctag taaagcaaat gcaggagaaa
     8281 atctgttgtc acaagagaag aaaatattat ttatcggtga ttctgttatg ctgggggcgt
     8341 atcaggaact aaaggagaca tttaaaaaag aagcattggt agatgcaaaa gaatcaagac
     8401 aaatcactgc gttaccagaa atcttaaagg agcataaaga tttagtttct taccaacaaa
     8461 tagtgatcgg gttaggaacc aatggtgtga taacagatga agctatagaa caaacaatgt
     8521 ctttgctgaa agataaaaaa gtatactggg taaatataaa agcaccaact ggctggcaag
     8581 atacgataaa tgccacatta gctacattgc caaatcagta ttctaatata acgatgatcg
     8641 attggtatag tgagagcaaa aatcatcctg aattttttta tgatgatgaa acccatttga
     8701 atgaaagtgg acgtacagct tatgcaaagt atattgcttc agttattcaa taaggtagtg
     8761 attacgtgtg ttaaccttac tttttcctaa taggtgaatc aatttaaata aaaaatactt
     8821 catatgataa acggtgttta agaggaggag ctttttaata ttcgtggtaa aaaagagatg
     8881 ggcgaggtcg ttaactgaga gcttcttgga aagaaatcgc tttggattta tcctctttgt
     8941 tatacagaac atgagcgaga cgacaatact aggatgtatg ttctgatcga agttttatgg
     9001 ttacaagcag caatcagctt agataaaatt aaggatcgta ggaaccaagt aaagaaggct
     9061 gttagtaaag aaacaaacga tcaagtatgt tttactctta agaagatgca gtgaataaat
     9121 aatagtaata taatgctaga agggactgtg acaaaagacg tgtcacagcc ttttttgtta
     9181 ttttaattat cgtccagtct ttttttataa atgattgctt aagcattaaa tattaaaaaa
     9241 tatagagttc aaaattactg cacaattaga tgaaaaattt gaacaacaaa aagtgtattt
     9301 ttatactata atagcttttg aatttagtta ctctattcaa aagttatgct atggacaaga
     9361 aaaagaataa atagaggtga gaaaatgaat agtttcaaga aaaaatttgt gagtagattt
     9421 ttaaatatga aaaatttttt tgaaaaaaag ggagattatg atgcatataa ttatgtatta
     9481 aatctagaaa agcaaacata ttatacacta cgtaaaaacg atgataatga cttttggact
     9541 atgttaccta aaatgctttc gattgactct aagctttccc ttttagagga atttattaat
     9601 ttagacattg aagaattttg cgggggaaaa gagttaatta atatggtaga gagtgattat
     9661 catacctatt ataaagaaag ttgtggatac aaagtggatg agcaatgtcc acaatcaatt
     9721 attttttaca ttgagtaata tgaactatta agcaggaaag caactagaag ctactgattt
     9781 agtatttaca aatataaact atattgctaa caattatttt ctagaaggaa taaaagaact
     9841 aagaatcaag acgttatctt gattcttagt tcttttaaca tggaaaagat ggataatgca
     9901 ctgttaattc atgatgcatc atcagaaaag ttggaaggag aagatagaaa tcattaaatg
     9961 atttctacag atggtaaatg aaaaaacaaa atattagcaa aaatttgcct aaatagatag
    10021 taacactttc taaattaaat acaagcgcat tcataaaatg tttatacaaa tatctatgtg
    10081 ataaaaattg gatatgttca caataaatag gaattaaaat aacgaattta cgtttgtttt
    10141 tatttaccaa tcaaattatc ttaatgcagg aataaaaaat taaattacat attgttaatc
    10201 atttacatct ccattaa
//
LOCUS       DAXLPC010000092        10022 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.093, whole genome shotgun sequence.
ACCESSION   DAXLPC010000092 DAXLPC010000000
VERSION     DAXLPC010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.093"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..722)
                     /locus_tag="ACF3UE_002283"
     CDS             complement(<1..722)
                     /locus_tag="ACF3UE_002283"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3635654.1"
                     /translation="MTYKNIVFDLDDTLYDHQLPFKRSVEKCFPTIDIQQIDNIYKRF
                     RCWSDVAFPKYTKKLISIEQLRIFRCQKTMEEFGIDSISRTEALDFQADYEYELDQIT
                     MIPEIHQLLLALHKNRIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGA
                     AENSYEGNVKNLQSYQNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRH
                     KPGMATVFLTNFIRCRTSFRML"
     gene            complement(727..1494)
                     /locus_tag="ACF3UE_002284"
     CDS             complement(727..1494)
                     /locus_tag="ACF3UE_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFD3635655.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            1983..2408
                     /gene="lacA"
                     /locus_tag="ACF3UE_002285"
     CDS             1983..2408
                     /gene="lacA"
                     /locus_tag="ACF3UE_002285"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HFD3635656.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            2425..2940
                     /gene="lacB"
                     /locus_tag="ACF3UE_002286"
     CDS             2425..2940
                     /gene="lacB"
                     /locus_tag="ACF3UE_002286"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HFD3635657.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            2951..3883
                     /gene="lacC"
                     /locus_tag="ACF3UE_002287"
     CDS             2951..3883
                     /gene="lacC"
                     /locus_tag="ACF3UE_002287"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HFD3635658.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            3886..4866
                     /gene="lacD"
                     /locus_tag="ACF3UE_002288"
     CDS             3886..4866
                     /gene="lacD"
                     /locus_tag="ACF3UE_002288"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFD3635659.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            4894..5211
                     /locus_tag="ACF3UE_002289"
     CDS             4894..5211
                     /locus_tag="ACF3UE_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD3635660.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            5211..6917
                     /locus_tag="ACF3UE_002290"
     CDS             5211..6917
                     /locus_tag="ACF3UE_002290"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HFD3635661.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            7059..8465
                     /gene="lacG"
                     /locus_tag="ACF3UE_002291"
     CDS             7059..8465
                     /gene="lacG"
                     /locus_tag="ACF3UE_002291"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFD3635662.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRLKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            8488..8761
                     /locus_tag="ACF3UE_002292"
                     /pseudo
     CDS             8488..8761
                     /locus_tag="ACF3UE_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
     gene            8782..9681
                     /locus_tag="ACF3UE_002293"
     CDS             8782..9681
                     /locus_tag="ACF3UE_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFD3635663.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDEDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSSLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         3164 a         1690 c         2006 g         3162 t
ORIGIN      
        1 aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac tgttgccatt
       61 ccaggtttat gacgactttt ggaagtaaaa atccatccat tatctttata atcaggattg
      121 aatcttatat gttggtgatt taactcaatt tcctctttaa gaatttctat agccctttta
      181 gataattgga cattttggta actttgtaag ttttttacat taccttcata gctattttct
      241 gcagctcctc cgtgagtgga ctgactaatg atgatatttt gcttttcaaa atattgatag
      301 gcaccaatat tttggagttt tcgactctgt aagtcaacag ggccattagt tagaatacct
      361 attgggatgc ggtttttatg tagagccagc agtagttgat gtatctcagg aatcatcgta
      421 atctgatcga gttcatattc atagtcagct tggaagtcta gagcttctgt cctagaaata
      481 ctatcgatgc caaattcttc catagtcttc tgacagcgaa aaattctaag ctgctcaata
      541 ctgatgagtt ttttcgtgta tttaggaaaa gcaacatcag accaacatct gaaacgtttg
      601 taaatgttat ctatttgttg gatatcaatc gttggaaaac atttctcaac gctacgttta
      661 aaggggagtt gatggtcata aagagtgtca tcaaggtcaa aaacaatatt tttataagtc
      721 ataattctag tccgctttta aaatagtagt gtactggcta aattcctcta agtgttgagg
      781 gctaatctgg ttatctgtaa tgatggtatc gagttgatct agattataga agttaaagaa
      841 atcgtatcga tcgaatttag tactgtctac taataagaat ttttctacag cattgtttag
      901 ggcaagttgt tgaatcacac cttccttgtc actatatgta gcaatagaat tatgggtaac
      961 agcatttgca ctaacaaaag ctttggcaaa tctaattgct tttaaatttg tcgaagccat
     1021 tgaacctaca aaagctccag ttatttctct atattcaccg ccaagaagca ataaatcaat
     1081 ggtttcgcta tcatttagaa tcaagaacac agggagacta tttgtaatga cacgaatttt
     1141 ataaccttta cgacctttca attctaatgc cagttgttca agtgtagttc cgggtccaat
     1201 aaaaatagta tcgccatctt tgattaaaga gcaggctttt ttagcaatgt caattttttc
     1261 ttttgtattt agacttttct tctcgatatg tgtcttttca agtggctttt tagaggaaag
     1321 taattgtgca ccaccatgag tacgtgttaa aagtccatca gcttctagag catcaaggtc
     1381 tctacgggct gtcatatcgg aaatatctag ttcatctatt atttctttta tggttatggt
     1441 cccatcaatc tttaacatat ctaaaatttt ttctaatcgt cgttttttgt tcatatgaag
     1501 acccttcttt cataaagtaa tttttttcca aagataattc tcttttaatt gtatcataaa
     1561 agacaatatt ttcaaggtaa aacaaacaat ttcaaacaaa aacaaatgtt agatgatgaa
     1621 ataagaacag tggattgacg tatattagct taggtcagat tttgtataag acgaaaataa
     1681 agtaggacct cttaatcagt aagttataga aagtaaaaga cttttgtaat acttgaatag
     1741 atatttcacg tccattttgt gatggattaa atgaacaaaa atgaacaata atttaacggt
     1801 gttatctatt ttttaagaaa acaaataaaa aaaacaaaaa ataaacaaaa aagtgttgct
     1861 ttttgtttga atgattgata ttatataaac aaagaaatga tgaaaacgtt ttttcgaaca
     1921 ttttgcaaaa tgttttctac ttctacgtag catttctttc taaaatttag gaggtggtca
     1981 aaatggctat tgttgttggt gcagatctca aaggtacgag attaaaagat gttgtgaaaa
     2041 attttcttgt agaagaaggt tttgaggtaa ttgatgtgac taaggacgga caagattttg
     2101 ttgatgttac cttggcagtt gcctctgaag taaataaaga tgagcaaaac ttaggtattg
     2161 taattgatgc ttatggagct ggtccattca tggtagcaac taaaattaaa ggtatggttg
     2221 cagcagaagt ttcagatgaa cgctcagctt atatgacacg tggacataac aattcacgaa
     2281 tgattacggt tggcgctgaa atcgtcggtg atgagcttgc taaaaacatc gctaaaggtt
     2341 tcgtcaatgg taaatatgat ggcggacgtc atcaaatccg agtagatatg cttaacaaaa
     2401 tgtgttaaga aaaggagtta aggaatgaga atcgcaattg gatgtgacca cattgtcaca
     2461 gatgaaaaaa tggcagtatc agaattcttg aaatcaaaag gacatgaggt ccttgatttc
     2521 gggacatatg accacgcacg tactcactac cctatctatg gtaaaaaagt cggtgaagca
     2581 gtagtaagtg gtcaagcaga cttgggagta tgtatctgtg gtacaggtgt cggcattaac
     2641 aatgcagtca ataaagttcc aggtgttcgc tcagcgttgg ttcgtgatat gacatcagct
     2701 atatatgcaa aagaagagtt aaatgcgaat gttatcggtt tcggtggaaa gattactggt
     2761 ggtcttctta tgaatgacat cattgaagct ttcattgaag ctgagtacaa accaacagaa
     2821 gaaaataaaa aattgattgc aaaaatcgaa cacgttgaaa cacataatgc acatcaagca
     2881 gatgaagatt tctttacaga attccttgaa agatgggacc gtggtgacta ccacgattaa
     2941 ggtataacaa atgattctga cagtcacact aaatccttca gtagacatct cttatcctct
     3001 agaaacattg aaaattgata cagtgaatag ggtgaaagat gttagtaaga cagctggtgg
     3061 aaaaggctta aatgttacta gagtcttgta tgaatctggt gataaagtta ctgctacagg
     3121 tttcttaggt ggtaaaattg gtgaatttat tgaaagcgaa ttagaacaat ctcctgttag
     3181 tccagctttt tataaaatct caggaaacac tagaaactgt attgctatct tacacgaggg
     3241 taaccaaaca gaaattttgg aacaaggacc aacaatttct catgaagaag cagaaggctt
     3301 tcttgaccac tatagcaatc ttattaaaca atcagaagtt gtgacaattt caggaagttt
     3361 accttcagga cttcccaacg attattatga aaaacttatc caacttgctt cggatgaagg
     3421 agtagcagtc gttttggatt gttcaggtgc acctcttgaa acagttctaa aatcgtcggc
     3481 taaacctact gccatcaaac ctaataatga ggaactttca cagttgcttg gaaaagaagt
     3541 aacaaaagat attgaagaac tcaaagacgt tcttaaagag tcacttttta gtggtatcga
     3601 atggatagtg gtctcattag gtcgaaacgg tgcctttgca aaacatggtg atgttttcta
     3661 taaggtagat attcctgata tcccagttgt taatccagtc ggatcagggg actcaacggt
     3721 agctggtatt gcatcagctt taaatagtaa aaaaagtgac gctgacttat taaaacatgc
     3781 gatgacattg ggtatgttaa atgctcaaga aacaatgaca gggcatgtga atatgactaa
     3841 ttacgaaaca ctaaactcac aaattggagt aaaagaggta taaaaatggt acttacagaa
     3901 cagaaacgca aatctttgga aaaaatttca gataaaaacg gtgttatctc agctttggca
     3961 tttgaccaac gtggtgcttt gaaacgtttg atggcacagt atcaagatac agaaccaact
     4021 gtagctcaaa tggaagaact aaaggttttg gttgctgatg aacttacaaa atacgcttct
     4081 tcaatgttgc ttgaccctga atatggactt ccagcaacaa aagcattgga taaagaagca
     4141 ggtcttcttc ttgcctatga aaaaacaggt tatgatacat caagtacaaa acgtttgcct
     4201 gactgcttgg atgtttggtc tgcaaaacgt atcaaagagc aaggcgctga tgccgttaag
     4261 ttcttgcttt actatgatgt agacagctca gatgaactta accaacaaaa acaagcttat
     4321 attgaacgtg ttggttctga atgtgtcgct gaagatattc ctttcttctt ggaaatcctt
     4381 gcttatgatg aagaaatctc agatgcaggt tctgttgaat atgcaaaagt gaaacctcgc
     4441 aaagtcattg aagcgatgaa agttttctct gatccacgct ttaacattga tgttcttaaa
     4501 gtagaagtac cagttaacgt taaatatgtc gaaggttttg ctgatggtga agtggtttac
     4561 agtaaagctg aagctgctga cttctttaaa gcacaagaag aagcgactaa ccttccatac
     4621 atctacctaa gtgcaggtgt atctgctaaa ttgttccaag aaacattgca atttgctcac
     4681 gactcaggtg ccaagtttaa tggtgtgctt tgtggacgtg ctacttgggc aggatctgta
     4741 gaaccttaca tcaaagaagg tgaaaaagca gcacgtgaat ggttgcgtac tactggattc
     4801 gaaaatattg atgaacttaa caaagttctt gttaaaacag ctagtccatg gactgataaa
     4861 gtatagtaaa aacataaaac ggaggatatt gttatgaaca gagaagagat gactctctta
     4921 gggtttgaaa ttgttgctta tgctggagat gctcgctcta aacttttaga agcgcttaaa
     4981 gcggctgaaa atggtgattt cgctaaggca gatagtcttg tagtagaagc aggaagctgt
     5041 attgcagagg ctcacaattc tcagacagct atgttggctc gagaagcttc tggggaggaa
     5101 cttccataca gcgttaccat gatgcatggt caggaccact taatgactac tgtcttatta
     5161 aaagatgtga ttcatcacct catcgaactt tataaaagag gagcaaaata atgcataaac
     5221 tcattgaact tattgagaaa gggaaaccgt tctttgagaa aatctctcga aacatctatc
     5281 ttcgtgctat tcgtgatgga tttatcgctg gtatgccagt catccttttc tcatctatct
     5341 ttatccttat tgcctatgtc ccaaatgctt ggggattcca ctggtcaaaa gacattgaga
     5401 ccttcttgat gactccttat agctattcga tgggtatcct agcattcttt gttggtggta
     5461 ctaccgctaa agctttgacg gactcaatga accgtgacct acctgcgacc aatcagatta
     5521 acttcttatc tacgatgcta gcgtctatgg tagggttcct tttgatggca gctgagcctg
     5581 caaaagaagg aggcttcttg acagccttca cgggaacaaa aggtcttttg acagcattta
     5641 ttgcagcctt tgtgacagtt aatgtttaca aggtctgtgt gaaaaataat gttactattc
     5701 gtatgcctga agaggttcca ccaaatatct ctcaagtatt taaagacttg attccattca
     5761 ctgtagcggt tgttctcctt tatggatttg aactcattgt taagggaact cttggtgtaa
     5821 ccgttgcaga atcaatcggt acccttcttg ctcctctctt ctcagctgca gatggttacc
     5881 ttggaattac acttatcttt ggtgcttatg ccttcttctg gtttgttggt atccacggtc
     5941 cttcaattgt cgaaccagca atcgctgcta tcacttatgc caatatcgat gccaacttgc
     6001 atcttatcca agctggacaa catgcagata aagttatcac ttctggtact caaatgttta
     6061 ttgttaccat gggtggaaca ggagctacat tgattgttcc attcttgttc atgtggattt
     6121 gtaaatcaga acgtaaccgt gccatcggac gtgcctcagt tgttccaaca ttctttgggg
     6181 ttaatgagcc aatcttattt ggtgcaccaa tcgtattgaa tccgattttc tttgtaccgt
     6241 tcattttcgc tccgattgtc aacgtttgga tctttaaatt ctttgttgac acattgaaca
     6301 tgaactcatt ctctgccaac cttccatggg ttactcctgg tccgttggga attgtactcg
     6361 gtactaactt ccaagttcta tcatttatct tagccggact cttggtagtt gttgatacta
     6421 tcatttatta cccatttgtt aaggtatacg atgaacaaat tcttgaagaa gaacgttctg
     6481 gtaaaacaaa cgatgctctt aaagaaaaag tagctgcaaa cttcaatact gctaaagcag
     6541 atgccgttct tggaaaagca ggcgttgcta aagaagatgt agcagcaaac aataatatca
     6601 caaaagaaac taatgtcctt gttctttgtg caggtggagg tacaagtggc ttgcttgcca
     6661 atgccttgaa caaagcagca gcagaataca atgttccagt caaagcggca gcgggtagtt
     6721 acggtgctca ccgtgaaatg ttgccagagt ttgacttggt tatcttggct ccgcaggtcg
     6781 cttcaaactt cgatgatatg aaggctgaaa cggataaatt gggcattaaa cttgcaaaaa
     6841 ctgaaggagc tcaatatatc aaattgacac gtgatggaca aggtgctctt gcatttgttc
     6901 aacaacagtt tgattaataa atttgtaaaa gttatttgag acgagattat tctttcagtt
     6961 ccttataata ttgttaacca tatcattgca tttcatttcc ttggtttccg gaactcagaa
     7021 tatcgtctca aatgcttttt ttgaaaggat ttatagttat gactaaaaca cttcctaaag
     7081 attttatttt tggtggtgct acagctgctt atcaagcaga aggtgcgact cacacggatg
     7141 gtaaaggccc agttgcatgg gataagtatc ttgaagacaa ttattggtac acagcagagc
     7201 ctgcaagtga tttttaccat aaatatcctg ttgatttaga attagctgaa aaatatggcg
     7261 ttaatggtat tcgtatttca attgcctggt ctcgtatttt cccaactggc tatggcgaag
     7321 taaatgaaaa aggtgttgaa ttctaccata atctttttgc cgagtgccac aaacgtcatg
     7381 ttgagccatt cgtgactttg caccactttg acacaccaga agttcttcac tcagatggag
     7441 atttcttaaa ccgcgaaaat atagaacact ttgtagatta tgccgctttc tgttttgaag
     7501 agttcccaga agtaaactac tggacaactt tcaatgaaat tggcccaatt ggagatggtc
     7561 aatacttggt tggtaaattc cctccaggca ttcaatatga tcttgccaaa gtcttccaat
     7621 cacaccacaa tatgatggtt tctcatgcac gtgctgtgaa attgtataaa gataaaggtt
     7681 ataaaggcga aattggtgta gtacatgcgt tgccaaccaa atacccttat gatccagaaa
     7741 atccagcaga tgttcgtgcc gctgagttag aagatatcat ccataacaaa tttatcttgg
     7801 atgcaaccta ccttggacac tattcagata aaacgatgga aggggtcaac cacatcctag
     7861 ctgaaaatgg tggagaactt gatcttcgtg atgaagactt ccaagcactt gaagcagcta
     7921 aagatttgaa cgatttcctt ggtatcaact actacatgag tgattggatg caagcctttg
     7981 atggtgagac tgaaatcatt cacaatggta agggtgaaaa aggaagttct aagtaccaga
     8041 ttaaaggtgt tggtcgccga atcgcaccag attatgtgcc tagaacggat tgggactgga
     8101 ttatttatcc tgaaggcttg tatgaccaaa tcatgcgatt gaaaaatgat tatccaaact
     8161 acaagaagat ttacatcact gaaaacggtc ttggatacaa agatgagttt gtagataata
     8221 ccgtttatga tgatggtcgt attgattacg tgaagaaaca cttggaagtt ttatcagacg
     8281 caattgcgga tggtgcaaat gttaaaggtt acttcatctg gtcacttatg gatgtcttct
     8341 catggtcaaa cggatacgaa aaacgttatg gactattcta tgtagacttt gacacgcaag
     8401 aacgctatcc taagaaatca gctcattggt ataagaaagt agcagaaact caagtgatag
     8461 agtaatatta cttgaaaatg taaaaaattg ttatccgata ctttagaaaa agtacaacac
     8521 ttatttagac caggctttga aaaggtatat attgttagtt tcgaagattg tcctatgatt
     8581 cctgagcttg aagctaccct cgttgctaaa atgtggtaaa tggtatgttt taactggaaa
     8641 agagtggatt tgccattctg atttagagtt atcagcattt gaatgggaat ttttacaatc
     8701 actcgatgta gaaatacgtg agactattca cttcgaggta aattatttgc ctttccaata
     8761 ataaaaagaa aggaattagt tgtgactatc gaattaaaaa acgagtatct tactgttcag
     8821 tttaaaacac ttggtggtca actgacttcg attaaagacg aggatgggat agagtatctc
     8881 tggcaagctg atccaaatta ttggaatgga caggcgccta ttctatttcc tatctgtggt
     8941 agtttacgaa atgattgggc tatttataga cctcaagaaa gacctttttt tacaggtctt
     9001 attcgtagac atggttttgt tcgaaaagaa gaatttattc tggaagaagt caatgataat
     9061 agcgtgacct ttagtattaa accaaatgct gagatgcttg ataattacct atatcagttt
     9121 gaactgagag ttgtttatac cttgaatggt aaatcaatta gaaccgaatt tcaggtaacg
     9181 aacttggaaa tggaaaaaac aatgccttac tttattggag cccatccagc attcaatagt
     9241 tctttagtag aaggtgaaaa ctatgaggat tattatattg aatttagtga ggttgagtct
     9301 tgctcgatac caaagagttt tcctgagaca ggattattag atttgcaaga tcggacacct
     9361 tttttggaaa atcaaaaaat tctcgatttg gactactcac ttttttccca tgatgccatt
     9421 acacttgacc agctcaagtc tcgtagcgta acgcttcggt caaggaagtc tggtaaaggt
     9481 cttcgagtag attttgatga ttttccgaac ttgattctgt ggtctacaac taataaaagt
     9541 ccattcattg ctttggaacc ttggagtggt ctctccactt cacttgaaga aggtaatttc
     9601 ttagaagata aaagacaggt aacgaaaatt tcacctcaag aaacttctag aaaaatctat
     9661 gatattacta tccttaatta aaatttgtta ttatttgagt cttcaataag atttgaatac
     9721 tcttaccttg tgatgataga ttggtcttct ccgtgccagt cttacatcgc aaggttttta
     9781 agttttttgt gggtctatgt caactgtagt gggtgacgaa aagctaatat ctaaagacag
     9841 tctggtagta aaaaataaga ttatttacta cttcttgatt taaaataata gtggagccat
     9901 taatttgtgg caaatttaat ttaatatttt gcctcaaatt agccacactt tttatagaac
     9961 taagaggaaa aatgaaattt tcttcctatt aatatagttg tttgaaatct taaatatagc
    10021 gt
//
LOCUS       DAXLPC010000093         9914 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.094, whole genome shotgun sequence.
ACCESSION   DAXLPC010000093 DAXLPC010000000
VERSION     DAXLPC010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.094"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(75..587)
                     /locus_tag="ACF3UE_002294"
     CDS             complement(75..587)
                     /locus_tag="ACF3UE_002294"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFD3635664.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(601..2898)
                     /gene="recJ"
                     /locus_tag="ACF3UE_002295"
     CDS             complement(601..2898)
                     /gene="recJ"
                     /locus_tag="ACF3UE_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFD3635665.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLMHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPVE
                     FLDLVAIGTIADLVSLTDENRILVSLGINAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSN
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     IMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(3040..3483)
                     /locus_tag="ACF3UE_002296"
     CDS             complement(3040..3483)
                     /locus_tag="ACF3UE_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFD3635666.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(3484..4272)
                     /locus_tag="ACF3UE_002297"
     CDS             complement(3484..4272)
                     /locus_tag="ACF3UE_002297"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFD3635667.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(4269..5210)
                     /gene="rnz"
                     /locus_tag="ACF3UE_002298"
     CDS             complement(4269..5210)
                     /gene="rnz"
                     /locus_tag="ACF3UE_002298"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFD3635668.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(5387..5974)
                     /locus_tag="ACF3UE_002299"
     CDS             complement(5387..5974)
                     /locus_tag="ACF3UE_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFD3635669.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(6195..7508)
                     /gene="obgE"
                     /locus_tag="ACF3UE_002300"
     CDS             complement(6195..7508)
                     /gene="obgE"
                     /locus_tag="ACF3UE_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFD3635670.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            7796..8806
                     /gene="gap"
                     /locus_tag="ACF3UE_002301"
     CDS             7796..8806
                     /gene="gap"
                     /locus_tag="ACF3UE_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFD3635671.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(8891..9826)
                     /locus_tag="ACF3UE_002302"
     CDS             complement(8891..9826)
                     /locus_tag="ACF3UE_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFD3635672.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         2724 a         2273 c         1716 g         3201 t
ORIGIN      
        1 agaatctgac ttttgagggt cgctttaaaa tcgcttcttt aagaataaca tcaagaatag
       61 cttctttttt ctgcttaata ttccattaat gtaatgatgt catatccttt gattttgtcg
      121 cgtccatgga gatccatcaa ttcgatcaaa aatgcgcagc ctacgactac accgcctaat
      181 tgttcgatca gttcgatcgt cgctttgatt gttcctccag tagctagcaa atcgtcacaa
      241 atcagcacac gttgacctgg tttaatggca tccttatgca atgtcaatgt atctgttcca
      301 tattctaatc cataagtcac ttcgatggtt tctcgaggta acttcccttt tttgcggact
      361 ggggcaaaac cgactcctaa ctcataagca acaggacatc ctacgatgaa tccacgggct
      421 tctggcccaa ctaccatatc aattcgtttt tcttttgcat aatttacgat ttgcttcgta
      481 gcttcccgat aagcgtcacc atctgccatc agtggggaaa tatctcgaaa cacaattcct
      541 tttgacggat agtcgggaat actggcaata taatctttta aatccactct ttgtttcctc
      601 ctaggttgtt aaccatttct ttatggtagg aatatcgctc aaaagcaaaa attcctcaac
      661 tttgatttta ttgagccgcc gctggtataa tctgctctca gtcaaaggat gactttctgg
      721 gctagcgact ttttgtaaaa caccgttctc tattgtaaca aatttcaatt caaaaaacac
      781 ctgtatcata aaaattaata atttttcagg gatacgcaaa tattgagcta ttgcttttat
      841 tttatgacgt atatcaattc gttcttgaga atggatcagt ttaaacaatt ttgcgtactg
      901 ttctcttgtg cctaccccat tcaaataggc ctcatcaggc gaaatcccca tcagataaac
      961 acgattgaat gaataagacc gaaaaacttc tttcagatcc gctaaatcat ctggacaatc
     1021 cataataact agagagttcg gttttctttt ttcaattatt gcctttacag aatctagtcc
     1081 ttcgaaaaca atcgcagctt cctggataat ctcaggcacg aatttcaacg tagaagaatc
     1141 aaatgctaaa taaaggctac cttccgacgt tcggctctgt tcacggaaac gttttgcccg
     1201 ccaatcaaat acttgcagac cacccacaga aaaatcagat accatcagct gcggtttctt
     1261 acgcccgttc cattcattga tcgaaagctt tcctaccaca tctacctgat tattcagcag
     1321 ttcttcttct tgagtaccaa aaccaaaagc gaccgcatca agctgactcg atgcattgga
     1381 aaggacaaat ttcagatgct gttggtttgc tccgattctt ttgatatttt ctgcttggac
     1441 ttgtcgaaat aaaaactgag gcaaaggatt atccgtacca aatggcgcca atagtttcag
     1501 ctcatcaatt cgctctactg ttacttcatt tggcagcaat acttcatcaa ttctcaactc
     1561 aggccctctc atcaagtcaa tttgatgatc gactatatat tggttcatct tctcctgtag
     1621 tatagtgaca ttttcacttg gcatcgttaa accgactgct gcatgatgtc ctccgaagta
     1681 agtaaataaa tctcgcatct ggtcaagcat ttcaaaaaga ttcaaggctt caatactacg
     1741 tccagatcct ttagctgatc catcttcttt taaagtaagg acaagcgttg gtttacccgt
     1801 ttcattcatt attttcccag caacaatgcc caaaacgcct tcatgccatc ctcggtttac
     1861 caatagatgg atatgattct ccttattgac catcgctaat gcttcttgtg ttatctgctc
     1921 tacgattgct tttctttctt cattgatctc attcaatttt tttgcttgaa cggatgcttc
     1981 ctcttcatca aacgtcgcaa gtaacgagac ggcaggacgt ggatcgccca tccgaccgat
     2041 tgcatttagt ctgggagcaa tcgaaaaacc gatcgttgtt tcgtctgcgt ccctcatttt
     2101 tacgccgctt tcttcaaata gcgcctgaag tcctatccgt tctgaatgat gaatggcatt
     2161 gattcctaat gaaacaagga ttcgattctc atcagtcaat gaaactaaat cggcgatcgt
     2221 tcctatcgct actaaatcca aaaattctac aggcggttct tccaataatg cagaagctac
     2281 tttgaatgct actccgactc ctgccaaatc tggaaatgga tagtgccccg ctggatgacg
     2341 agggtgaaca atcgcataag cgtctggtaa attctcaggt agttcgtgat gatctgtaat
     2401 gatcacgtct acaccagctt gctgagcgta tgctaccgca tcatttcctg ctaccccgtt
     2461 atcaacagtg atgatcaact ggattccttc ttcgatcttt tcttggtata cagattggtt
     2521 tggtccatac ccatgctcaa atcgatttgg caggaatact tctacttctg caccaagtaa
     2581 ttccagtgtt tctttcatta ccgttgcact ggtgatccca tctgcgtcat aatcaccgta
     2641 aacgaggatt ttttctccac tgattacagc ttcttggatt cggctgattg ctttatccat
     2701 atcgtgcatc agatacggat catgtaattc ttgttccttt ggatgtaaaa atcggttgat
     2761 atccttttcc tcatggtaac ctctttgcca cagtaactta ccgacaaatg gagataattt
     2821 cagttcacgg atcatttgga gaaaggattc agaaggctct gtctcgctta acttccaatc
     2881 aaaatttgct tgtctcactt tctcactcct aacttagtta ttatagcaaa ggaaatcagc
     2941 aaaaaaaagc agaaagaaag aataaaaaca gatcagatcc gctagacaga tgttcagcag
     3001 gacctgatct tttgtacgac catttatgaa atatccctat tagtcaaaat aattgaagct
     3061 ttgtttgggc gattgagttt tttgttcttc cggcgctttc aattgactga tttgtgcggt
     3121 tttcgcttgt aactccgcct gataagcagc ttccaactcc gcacgttcgt ttctaaactc
     3181 gcgttgctgt tcttcttttg cttcttcaat tttcttttga agttctgttt gatattctga
     3241 catttcctga gtcagctgtt tgatttgctt tttttgctgc catagtgttg ccgaagcagt
     3301 caaaaataca atcagtgcac caatcagcgc agaaccgatg atcactaaga tcaatggcgc
     3361 agaaaaggaa gtgaagccaa aacttacagg aacattttta ttgttcaata cagcaaaaag
     3421 aacaataatc aaaactaaaa caaatccaag aatcacattg ctttgctttt tcaattcctt
     3481 cacctacttt ttgttaaaaa ttccgctggc taaataatca ccaatcgttg gaaacagcgt
     3541 ataaaatttt gatgcaactt ctaaaataaa cggttgattg atttcccgtt ttggatgtct
     3601 catattgcgg acgatcattt ttgccaactt ggcaggttct aaaacgattt gtccgacttt
     3661 ttccaaatag cttccgcttg gatcagcctt atcgaagaaa tctgtctcga ttggacctgg
     3721 attcactgtc gtaacagcta cgccaagtgg tttcaattct aatcgcaaag cgttggagaa
     3781 gccaaggact gcaaatttcg tggcagaata aaccgttgat tttgcagttg ccatttttcc
     3841 agccatagac gcgatattaa tgatatgacc ttgtcttctt tctgccatat cgatcgcaaa
     3901 tttttgtgtc aaaaccatca ttcctaagat gttgacttca aacatatcgt atgcttttcc
     3961 aaggtcgaat gtaaggaagt cttcgaaaat cccaaaaccc gcattgttta ccagaatatc
     4021 gacgcgcccg acttcttcca tcaccttttc atataattcg tccacgcttt caggattgct
     4081 gacgtctacc ttgaaagcat aagcctcttt gccgctcaag cgtctgcact cgtctctgac
     4141 accttctaca aatgccattc ttcgtgcgca acttataacg attgctcctt gctttgctgc
     4201 ttcataacag atttgtgcgc ccagaccgcc tgaactacct gttactaaaa caactttatc
     4261 ttctaaattc atgcctcttc ctcctcgcga aatggaatct caatgctatc aaaatctttc
     4321 atgatcgtcg tgttttcaaa cacttcttgt gcttcttttt caagctctaa agctgctttt
     4381 cctaaatatc tcgcactgat atgagtaagt agcagccgtt ttgcctgcgc ttcttttgca
     4441 acttcagcag cttgatgagt cgtggaatgg aaatagttgt gcgccattct tgcttcatct
     4501 ttattaaatg tgctttcatg taccagaata tcgctatttt ccgcaagcac aacggaatta
     4561 tgtgtttttc tcgtatcgcc taaaatagtc acgattcgtc cttttttatc tggacctacg
     4621 aaatcttttc cattgatcgt ccgcccatct tctagttgga tcgtttcacc ttgcttcagt
     4681 ttgccgtaca gtggtccagc tggaatacct aattctttta gacgatccac ctgcaattct
     4741 cctttatgat catgttcaac cacacgataa ccaaaactgt cgatcccatg atttagtttt
     4801 tttgtataaa cagaaaattg ctgatcagta aaaatcgggg ctgtttcatt tagctcaatg
     4861 aatttcagcg gataacttaa acgcgtttgc gaaataccta aagagacttt tatgtattcc
     4921 tctatccctt ttggcccgta aatctctaat ggcgtatccc caccttgaaa tgaccggctg
     4981 ctgatgagcc cgggaagtcc aaaaatatga tcgccgtgta aatgtgtaat aaaaatttta
     5041 ccgatttttc tcggacgaat agtcgttcgc aaaatctgca tttgcgtgcc ttcgccacag
     5101 tcgaacaacc aaacttcatt gcgctcgtct aaaagtttca atgctatact tgtcacattt
     5161 ctatgttttg caggaacacc tgcacctgtt cctaaaaatt gtaattccat aatctacctg
     5221 actttcttta agttcctctt taattttagg gtaaaaagaa gggataatca accgtaagtc
     5281 gagaatgggt tcaaattaaa aataacgttc taaagcgata gcgttttctt tgaaaattac
     5341 tataaaaaca gcagcgaacc cgtttgagat cctctgctgt tttttattaa tttgaagatc
     5401 cagaactttc attgtcgttg gaagtttgcg gatgtttgtc cttccaagtc ttttgtgcag
     5461 cttctttcgc atgattttca gcttctttcg catcatgcac atctttttcg acatcttcat
     5521 aatccaagcg ggtaatttct ccgcctaatt ccatcattac caattgattc agtgggcgat
     5581 tgtcctcttc atcagcaatc aagatcagtc ctgtagctcc ttcaccgatt ttatttccta
     5641 caaagtcgaa cacggtctgg gcatctttta tttctttggc atcttgtgtc gcaccgatca
     5701 ttcctccggc aaaccatcct aataaaatcc ctagcggacc acctaataca ccaaccaaca
     5761 ttccgattaa tccacccgta gaagatttgt tattaccggt aaagtcgata aaatcttcta
     5821 ttttgaattg atgtgtccca ttaggatcat ggctgacaac tgccatctgt tctcctttaa
     5881 tcgaacgaac agcatgtaac tttttgattt ctgaaaatgc ctgatatgcc tggctttcta
     5941 cttgaaaatt taaaatgatt actcgtttgc tcattaaaaa cgcccctttc ataccttctt
     6001 gttatttatt ttacctttaa ttgtaaaata agaaaagaaa agcactcttt ttttccaata
     6061 aaatagggct gtgacaaaag tcgtatcaca gctccttttt ccgaataaac ggcgttcttg
     6121 aagctgatca cttctgtcac aacctccctt aaatctgaat ctatattttt tggtatttgt
     6181 ttttatttgc ttgcctattc gacaaattca aattcaaact caccgatacg tacaaggtcg
     6241 ccatctttcg caccgcgtgc ccgaagagct tcatccacac ccataccacg taattgacga
     6301 gcaaaacgca tcactgtttc atcatgatcg aaattcgtca tttggaataa tttttcgatc
     6361 ttctcaccag ataagatcca cgttgcatct gaatcacgat cgatttggaa ctcaggacct
     6421 tctggattga atccatagtg tacagtttct tcttccagtt cttcttcgta caatgggaat
     6481 tctggcgtta cttctaacaa atctgctgta gcattcaata acgcgtccaa tccttgtcga
     6541 gtcactccag aaattggaaa tactgggatg tcatcagcaa attcatcttc tttttccttg
     6601 ttcagctgtt ctttgaattt cactagattt tccggtgcat ccggcatatc cattttgttt
     6661 gccacgatga tttgcggacg ctctagcaag cgtaagttat aagtagataa ttctttgttg
     6721 atggcaagat agtcttcata aggatctcgt ccttccatcc cactcatatc gatcacatgt
     6781 aaaattactc gtgttctttc gatatgacga aggaattgtg tacccagccc aacaccttgc
     6841 gaagctcctt caatcaagcc tggcaagtct gctgcggcaa aacttctgcc atcacttgta
     6901 gtaaccattc ctagattagg gacgagcgtc gtgaaatgat aagcgccgat ttttggacga
     6961 gcagatgaaa taacggatag taaagtcgat ttcccgacag atggaaaacc tacaagtcca
     7021 acgtctgcca atactttcaa ttctagttcg atttttcgct cttgtcctgg ttcgccgttt
     7081 tcagcaattt ccggtgcagg attccgagga gaggcaaaac ggatattccc tcgtccaccg
     7141 cgtccacctt ttgccacaac tagtgtttga ccattttcaa ttaaatctcc taaaagagca
     7201 ccagtctccg catctcggac agtggttcct tgtggtactt taacataggt atcttctgaa
     7261 ccacgaccgt gcatcccttt actcatccca ttttcacctg gctgcgcttt gaaatggcga
     7321 ttgaaccgaa aatccatcaa tgtacgtaac ccttcatcga cgatcaagat gacatcgccg
     7381 ccacgaccac cgtctccgcc agccggtccg ccgtcaggaa cgtatttttc gcgacgaaat
     7441 gcaaccattc cgtctccgcc cttgccagct ttcacatcga tcgttacttg atctaaaaac
     7501 atggacataa ttaagtcctc ctattattca tttatttatt tgactgcctg aatttccaca
     7561 ataaacaaaa gtcttactta ttttatcggt gaaatctgat tttgtctatc atttcagcaa
     7621 aaagattgtt taccttcttc tttttttatc atttggtaag gtttccaacc ttttttctgc
     7681 taccaagtat aattttttga caaaatattc tttgcgtagc agaataacag tgtattaatt
     7741 gtattaattg aggatgccgt ttcacagcac ccctaataaa ggaggaactt ttgatatgac
     7801 agtaaaagta ggtattaacg gatttgggcg tattggccgt ctggctttcc gccgcatcaa
     7861 agaagtctca gatgatattg aagtagtagc aatcaacgac ttaacaagtc caactatgtt
     7921 agcacaatta ttgcaatttg actctactca tggtacttat cctggcacag ttactgcaac
     7981 agaagactca atcgtagtgg atggcgaagc aactcgtgtt tatgcagaac ccgacgcaag
     8041 caaaatccct tgggcaaaag aaaacggtgt agatatcgta ctagaatgta ctggttttta
     8101 tacatctgaa gaaaaagcaa aagcgcattt agatgctggt gtcaaacgag tagttatttc
     8161 tgccccagct ggtgctatga aaaccatcgt ctataacgtc aatgatgata cattagatga
     8221 aaacgacaaa atcatctcag caggttcatg tacaacaaac tgtttagcac ctatggctta
     8281 tttcttaaat aatgaatttg ggatcgaagt tggtacaatg acaacagttc atgcctacac
     8341 ttccacacaa atgctcttag atggacctgt aaaaggcggt aatttgcgtg ctgctcgttc
     8401 agctgctgac aatactatcc cacattctac tggtgctgcg aaagcaatcg gcttagttat
     8461 ccctgagcta caaggaaaat tacaaggaca cgcacaacgt gttccagtcg ttgatggttc
     8521 attaactgaa ttggtttcag tattgaaaac aaaagtaact gctgatcaag taaacgaagc
     8581 aatcaaaaaa cacacagttg acaatccttc attcgggtat gatgaccgtc aaatcgtttc
     8641 tagcgatgtc attggaacaa ctcaaggttc gatctttgac ccaacgcaaa cagaagtaac
     8701 aactgctggt gatttccaac ttgttaaaac tgttgcatgg tatgacaatg agtatggatt
     8761 tacttgccaa atgattcgct tactagaaaa attcgctaac ttgtaatttg atagatcaat
     8821 cgataaaaga agcctttgac tggatccagt caaaggcttc tttcttttca tcccctactt
     8881 ttaaactcgt tcaatgaaca tattggctta aaaattgttg gactacttgc tgatattttt
     8941 caggatctgt cttgtatgct tccgcatgct cggctccttt tacaacatac ttttcttttg
     9001 gtcccttcgt tgcacgatag accttatcta acatttcaaa tggtacaaat gtatcttcgt
     9061 ctccatgtat aaagagcatt gggcgctggt ttttcttcaa ttgttccact gcatttgctt
     9121 caccgaaaaa gtagccagca cggacttttg tcactagact cgttacttgc ataagcggaa
     9181 atgctggaag actaaacata tcgtctagct gataagcaag ctcatcatga acggaagaat
     9241 aaccgcaatc ttcaatgatt gctttcacat tatctggtag tttttctccg ctagtcatca
     9301 taactgttgc tgctcccatg ctgacaccgt atagaacgat ttcttgcgat tttccattgt
     9361 tttctagcac tttgtttatc cactgtacat agtctttacg ctctggccat ccaaatccaa
     9421 tgtaatcccc ttcgcttttt ccatgtcctc ttgcatcagg aacaaggaca ttgtaaccca
     9481 tatcatgaaa catctttgcg taattggtca tcgtttcagc gtttcccata tagccatgag
     9541 ccacaagagc tgttttttca cttttcgttt cagcaggaag ataaatcgct gataatttca
     9601 gaccgtcttt tgaagtgatg gtccaatcgc ttcggttttc ttttgaacta aaccatttat
     9661 gtgcatccgt ttctttggat gtctgtgttg taccaggtgt atcttcgtct aaaaagtctt
     9721 tctcagaagg cacaacagca taattataaa aataattccc tgcaaacact aacgcaacaa
     9781 tcagagctaa agcgacgcct aaaaggattt tcatccaaag tttcataaat catccatctc
     9841 atttctcttt tttcatataa ccttgaatta gtataatcaa agaatctcta ctatgcaatg
     9901 ttcattttta taac
//
LOCUS       DAXLPC010000094         9692 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.095, whole genome shotgun sequence.
ACCESSION   DAXLPC010000094 DAXLPC010000000
VERSION     DAXLPC010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9692
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.095"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            214..993
                     /locus_tag="ACF3UE_002303"
     CDS             214..993
                     /locus_tag="ACF3UE_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635673.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTIVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIDQIRNEKIRAAYATKAQTVAQQMGYSNISY"
     gene            1039..1983
                     /locus_tag="ACF3UE_002304"
     CDS             1039..1983
                     /locus_tag="ACF3UE_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFD3635674.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            1999..2778
                     /locus_tag="ACF3UE_002305"
     CDS             1999..2778
                     /locus_tag="ACF3UE_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HFD3635675.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKEAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGSAPARPKATNGKTAPSRRSRSRV"
     gene            2790..3488
                     /locus_tag="ACF3UE_002306"
     CDS             2790..3488
                     /locus_tag="ACF3UE_002306"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFD3635676.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLSNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQIFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLSKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3516..4280
                     /locus_tag="ACF3UE_002307"
     CDS             3516..4280
                     /locus_tag="ACF3UE_002307"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFD3635677.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFRKNPNYLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIGKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            4293..6110
                     /locus_tag="ACF3UE_002308"
     CDS             4293..6110
                     /locus_tag="ACF3UE_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HFD3635678.1"
                     /translation="MFVLTRRRKIATLVVVDSLLLIAANIAAAKFMKPFVAIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            6122..7087
                     /locus_tag="ACF3UE_002309"
     CDS             6122..7087
                     /locus_tag="ACF3UE_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HFD3635679.1"
                     /translation="MNILILSCGRRCELVNAFKTALNNNEMEGKIIGADCSELAPALY
                     MCDEKIVLPKVSESNYIEELIKVIKFFEIKLIVPTIDTELSTLSRNKKYIENETDSVV
                     LVSSEKVIDICENKILTSAFFEQNGFKTPEILNSSEITKFPVFIKPLNGSSSVNTFIV
                     NNEKELLFFSEYIDNPLIQEYILGEEYTIDVCLNFDSTPVSIVPRKRIATRGGEILKG
                     QIIKDRELIETTKKMLEKLNAIGHITIQCIKNEKGIFYLEINARYGGGAPISIKSGAN
                     SPEYIIKMIDSKKNLRYRENYLDKMIALRYDQAIYLDEKGNVYND"
     gene            7080..7775
                     /locus_tag="ACF3UE_002310"
     CDS             7080..7775
                     /locus_tag="ACF3UE_002310"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFD3635680.1"
                     /translation="MIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIFPATFDEI
                     YRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLENADTLLTE
                     LRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPISYLLLLE
                     KFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFYQADKKIR
                     SLWEIKNFLGVIS"
     gene            7772..8890
                     /locus_tag="ACF3UE_002311"
     CDS             7772..8890
                     /locus_tag="ACF3UE_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HFD3635681.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            8880..9500
                     /locus_tag="ACF3UE_002312"
     CDS             8880..9500
                     /locus_tag="ACF3UE_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFD3635682.1"
                     /translation="MMRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLG
                     SPIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELP
                     ELWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKF
                     DLDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
BASE COUNT         3502 a         1540 c         1942 g         2708 t
ORIGIN      
        1 attgttatct tattaatgtt ttatttattt ttaaatcgta aattgcccta gtcaagaaaa
       61 cagtttgtgg tatgattata tagggaaaac ttgtttacaa atatttctgt gaatatatta
      121 gtttaattat gttttttaaa ataaaaagct gtcattttta tgtaagtgaa ttatatctta
      181 atttatctat catcaatact taggagtgaa tctatggaaa agccattcgt caagtcattg
      241 actgctgtgg cggtaggtgc aggtgctatt gcgatctgtt tgtttggtta ccatatcaat
      301 aatcagcggc aacatcagca acggatcaat tatgcagaat ctgccatcac caatcaaaaa
      361 gacaccttga cttctttatc aaaagaagta gacaagctgt atagtacaaa agaaaaaaat
      421 tttctaaacc ctgaaataac agaagaaaca atcacaagtt tgtcaaataa gctatcctct
      481 gtcaaacttt cagcagatga ttacgacatc aaagaatcag aattgcctaa agaagctgtt
      541 gcaatccaag atgagaagaa agcaatcgtg acacagttag atagtgcaga atcaaaactg
      601 aagatccaga cagctgtcaa cgatttattt actaaaaatg tatcaaactg gcagcaagct
      661 gtagacgatg tcgtcatcaa agaaaaggtg acaagtgcag atgtcgctcg tgtacgtgaa
      721 aatatgagct tttttaaaga tagtccttgg aaaacgattg ttatgcaata tctaggattc
      781 gctgatactc agatcgcgca agtcacgcaa ctagatcagt tattcgatac gatgttgaag
      841 gatggtcaag tgactgccac cgctacttac gatcaatatt tgacggtgct cagtcaaata
      901 gatcagatcc ggaatgaaaa aatacgcgca gcatacgcaa caaaagcaca aactgttgct
      961 cagcaaatgg gctatagcaa tataagctat tgacagttaa aacgttgatt caagcaaggt
     1021 tagcaaacgg aggaaactat ggcaagacga agaagaaaat caagagggaa aaaaatattt
     1081 ctgattattt tagcagttct tatcgtatta gtattagcaa ttgtaggagt aggagcaaaa
     1141 ttatatctgg atctctcaca ttctattgag aaaacttacg aatcagtgga acgaacccaa
     1201 ggagaacgaa cgaaaccagt tgatctggac aaacaagaat ctttctctgt tctattgatg
     1261 ggcattgata ctggagattt aggtcgggtc gatcaaggaa gatcagatac gatgatggtt
     1321 gccacagtca gtcctgaaga caaacagaca acgatcgtca gcattcctcg agatacgtat
     1381 gtcgacatcg taggtcgtga cacaaaagac aagatcaacc acgcttacgc attcggcgga
     1441 gctgccatgg cgatggatac cgtacaaaaa tatgtagaca tcccaatcga tcactatgtc
     1501 tctatcaaca tgaaagggct aaaagaactt gttgatgcag ttggtggtat cgaagtcaat
     1561 aatgacctca ctttctcaca agatggctat gactttacaa tcggtaaaat tactttgaac
     1621 ggggatcagg cattatctta ttctcgtatg cgttatgaag atccaaatgg tgactatggt
     1681 agacaagagc gtcaaagaaa gatcgtagaa ggtgtagcga aaaaagtatt gagtctaaac
     1741 ggtgtcagca actatcaatc cgttttgaat gctctagagt cgaatatgaa aacagacatg
     1801 agctttgatg aaatgaaaaa aattgcttta gattatcggg aggcatttgg tacgatcaag
     1861 caagatcagc tgcaaggaga aggcttcatg caagataata tctcctatca aaaagtcagc
     1921 gatcaagaac ttgatcgtgt gaaaaaagaa ttaaaagatc aaatgaatct agagaataaa
     1981 taggaaagtg gagaaaaaat ggaagagaca atcagcttga aagaaatttt tgaaacatta
     2041 cgcaaacact tggtaacaat catcatctca atgtttgctg gcttggccat ctcaggaatc
     2101 gtaacatttt tcatcttgac accaaaatac agttcacaag cacaattgat cgtgacactg
     2161 ccacaatcag acacagcaaa tgtcaatgat gtcaatacga acctgcaaat gatcaatacg
     2221 tataaagata tgatcgtcag tgatttagtg ctaaatgaag tcaaagatcg tttagaaaca
     2281 gaagacaatg tgaaaatgac tgctgaacaa atcaaagagg ccatctcagt caatcagtca
     2341 caaaattcac aaatgttctc gatccaggca ataagcacga atgcagtgac tgctcaacag
     2401 atcgctaaca caacttcaca agttttccaa gagaacgcaa aagacgtgat gaatgtcgat
     2461 aaaatctcga ttatttcagg tgcagttgcc aatacgacac ctgtttcgcc aaataataaa
     2521 ttgaatttag tgattggctt agtattagga atgatggtag gcgtaggtct ggcattctta
     2581 ttcgaattac tcgatcggac agtgaaagat gaaaaatatg tgacggatac attaggattc
     2641 ccaatcttag gaacagttcc agaaatgtca gcgaaagaat tgaacgctgg tatccgtaaa
     2701 aaaggatcag ctcctgcacg accaaaagct acaaatggta aaacagcgcc atcacgcaga
     2761 agccgctcaa gagtctagga ggaagaaaaa tggcacgaac acagaaacaa aaagcagcac
     2821 aaactcatgc agtcagtttg atcacattaa caaacccatc ttcaccaatc gccgaacaat
     2881 atcgtacgat ccggacgaat atccagtttg cctccgcagc tggtcagcaa atcaaaacga
     2941 ttgtcgtgac ttcatcaggt cctggagaag gaaaatccac cactgcagca aacattgcag
     3001 tcgtttttgc taaatccggt caacgggttc tattagtcga tgcagattta cgtaaacccg
     3061 tcgtctataa aacattccag ttgagcaatg ctagtggatt aagtacagca cttagttcat
     3121 caggaagtgt agcagatgtg atccaacgaa cgccagtcga gaacttgtcg attttgccta
     3181 gtgggcctaa gccacccaac ccatcagaat tgttaagctc gccaagaatg gatcagattc
     3241 tagccgaagc aagacagata tttgacgtgg tgatattcga tatgccacca gtagtagccg
     3301 taacagatgc acagatcatg tcttcaaaaa cggatggcac tttattggtc gtacgtgaaa
     3361 atacatcacg taaagaatcc ttgtctaaag caaaagaact gctagagatg gtacaagcac
     3421 gagtcttagg tgttgtatac aacggagcag aacatagcaa agatgctggt tattactacg
     3481 gaaattaagg aataagaaga gaggagacaa gagaaatgat cgatctacat tgccatatcc
     3541 taccaggaat cgatgacggg gcagaaaact tagaagcaag tattgcaatg gctgaaaaag
     3601 cgattcagca aggcatcacg catattttat gcacaccaca ccacaataat ggaaaataca
     3661 gcaatgaaaa atcacaagtc atttctctag tcgcttcgtt acaagccgaa ttagagaaaa
     3721 gacaattgcc tttgacgtta ttggaaggac aagaagtacg tattaccgga acgctcatcg
     3781 aagacatcca ccgagatgaa attttattta cagatttaga tgatacatat cttctgatcg
     3841 aatttccgac actggaagtg ccgttatatg cagaacggct tttttttgag ttgttagaac
     3901 taggaaagac accagtgatc gtccatccag aacgtaacgc gcattttcgt aaaaacccga
     3961 attatttgct tccgttccta gatatggggt gtttggccca acttactgcg ccaagttatg
     4021 ttggggtgtt tggcaaagac atccagaaaa cagctaaaac gatggtcaaa cataatctcg
     4081 tgcagatggc tgcttctgat gcccatgggg tctctaagcg caccttttac ttaaaagagt
     4141 gctatgagca gattggcaag gactttggta aggaaaaagt agtacagatg aaacaagtcg
     4201 caaaggatct gatcaacggg gatgaaatca gttatccagt ctatgaagag gtaaaaaaga
     4261 agaaatttgg tttattttag ggggaatgta gggtgtttgt attaacaaga agaagaaaaa
     4321 ttgccacatt ggttgttgtg gacagcttgt tattaatcgc tgcaaatatt gcagcagcta
     4381 aattcatgaa gccgtttgta gctataccaa tggaccttat tttaatctct attggtttgt
     4441 cgattggttt ttatttattt tatggtagtt tatttaaagt tttcactcga atcaatcgct
     4501 atacaaattt aagagagatc attgcaattt ttagttcact atctgcaagt gctgcctcaa
     4561 gtatcctcat actgctgttc attaatcggc gatacagttt acggttagtt atctttgctt
     4621 atctgctttc gctcttattg atcatcggta gccgattgat ctggcgtatc tacatcgaaa
     4681 caaaaaatat gagatatgta tcagcagatt ctgctaaaaa tacattgatt gttggtgctg
     4741 gcgaaggcgg gcgtatttta tacaacagct ttcttggatc caaaacggct caagatatcc
     4801 acgttgtcgg gttcgtagat gatgatccaa ataaaagaaa tacgtatctt tcaggaaaaa
     4861 aagtattagg tgcattaaaa gatattccgg aattgattga aaaatatgac attcaaatgg
     4921 taacgatcgc tatcccttcc ttatcaagaa aaaaattacg aagaatcttc gagttagtcg
     4981 aatccgctcg tgtgaaagtc aacacgatgc cttctataga agaacttgct tcaggaaaaa
     5041 ttagcgtatc aaaattaaaa acaattgacg tagtggattt actgggaaga gatgaggtaa
     5101 agctggatat tgaatccatc aaagatcaga tcacagacaa agtcattctt gtcaccggcg
     5161 caggaggatc gatcggttca gaaatctgtc ggcaaatcat tcaattcaat cctgcaaagc
     5221 tattgctttt aggacatggg gagaactcga tctacttgat tgaccgtgag ttacgcacgc
     5281 atcatcaaaa ttgtcctaca gaaatcgtac cgatcatcgc agatatccaa gatcgcgaga
     5341 aaatcaatga gatcatggaa caatatcatc cagatatcgt ctaccatgca gctgctcata
     5401 agcatgtacc actgatggaa tataatccaa aagaagcagt caaaaacaat attttcggta
     5461 caaaaaatgt agcagaagca gctaaagcag caaaagtgaa aaacttcgtc atggtatcga
     5521 cagataaagc taacaatcct ccaaacgtca tgggttcaac aaaacgaatc gctgaaatga
     5581 tcgtgactgg attgaatgaa gaaggctgta cgaaattctc agctgtcaga tttgggaatg
     5641 tccttggttc tcgcggtagt gtgattccag tattcagaga acaaattgct caaggtggtc
     5701 caatcactgt aacagacttt cgtatgaccc gatacttcat gacgattcct gaagcgagtc
     5761 gtttagttat tcaatctggc gcattagcaa aaggtggcga aatttttatt ctagatatga
     5821 gtgaaccagt gaagattgta gacctagcca aaaacatgat ccgattgagc gggtatagcg
     5881 aagacgaaat cgaaatcatt gaaacaggta tccgtccagg ggaaaaacta tatgaagaac
     5941 tattgttgga taaggaaaga aatgatgaag cagtttatga gaaaatcttt gtaggaaaca
     6001 tcaaaggtta ctcaatacaa aaagtgatgg attttgttaa gagcctgcca caagacgatg
     6061 aacaactggc taaagacatt gtcacttttg caaatgcttc gaatagatag gagattaaaa
     6121 attgaatatt ttaatattaa gttgtggacg tcgttgtgaa ctagtgaatg catttaaaac
     6181 agcattaaac aataatgaaa tggaaggaaa aatcattgga gcagattgct ctgaactagc
     6241 acccgcacta tatatgtgtg acgaaaaaat agtattacct aaagtttcag aaagtaatta
     6301 tattgaggaa ttaataaaag taataaagtt ttttgaaatt aaattaattg ttcctactat
     6361 tgatactgaa ttatcaacat tatcaagaaa taaaaaatat attgaaaatg aaacagactc
     6421 agttgtatta gtttcttcag aaaaagtcat cgacatttgt gagaacaaaa ttttaacttc
     6481 tgcttttttt gaacaaaatg gttttaaaac tcctgaaatt ttaaactctt ctgaaattac
     6541 aaaatttcct gtatttataa aacctctgaa tggtagttca tctgttaaca catttattgt
     6601 aaataatgaa aaagaattgt tgttttttag tgaatatata gataatcctc ttattcaaga
     6661 gtatatttta ggtgaagaat atactataga tgtttgctta aactttgatt cgacaccagt
     6721 aagtattgtt cctagaaaaa gaatagcaac tagaggtggg gaaatactga agggtcagat
     6781 tattaaagat agagaactaa ttgagactac gaaaaagatg ttggaaaaat taaatgcaat
     6841 cggacatatt actattcaat gtataaaaaa cgaaaaggga atattttatt tagaaataaa
     6901 tgcaagatac ggtggaggag cccccattag cattaaatca ggagctaatt cccctgaata
     6961 tattataaag atgatagatt caaaaaaaaa tttgagatac agagaaaatt atttagataa
     7021 aatgatagca ctgagatatg atcaagcgat ttatttagat gaaaaaggaa atgtatataa
     7081 tgattaaagc ggtgatcttt gatttagatg acactcttgt gtctgaatat gattatgtaa
     7141 aaagtggata caaatgtgta gctagaagat tagcagtgca aaaaattttc ccggctactt
     7201 ttgacgaaat atatagagtc cttttagatc tttttgctga agatagtaaa aatgtattta
     7261 atcgtctata tgactatttt gaaattcctt atagtaaaaa agaaattaaa gaactggtaa
     7321 atgtatatcg agaacacaaa ccagacataa attttttaga aaatgcagat actttattaa
     7381 cggaattaag aagtagagga tacaagctgg ggattattac agatgggtat gctataaccc
     7441 aacgaaacaa attggatgct ttgaaagtag actatttggt agattatatt tgtattactg
     7501 acgaattagg ccgtgaattg tggaaaccac accctatctc atatctttta ttgttagaaa
     7561 agtttaattt aaaggcacaa gagtgtatat atattggcga taatgagttg aaagatttta
     7621 taactgccaa atcaatagga atgcaaacaa ttaaaataga aagagtaaat ggtatttaca
     7681 gagaaagcag tttgaagttc aaaagatttt accaagctga taaaaaaata cgttcgttat
     7741 gggagataaa aaattttttg ggagtgattt catgaaaagt aaaagaattc tattagcttc
     7801 tccacatatg agtgaagaag gatatgaaaa agagtatgta aaagaagcat ttgatacaaa
     7861 ttgggttgct cctttaggtg cgaatgtgaa tggatttgag aaagaattag cagaatacgt
     7921 gggagctagt catgctgccg cattatcttc tggaacagca gctatacatt tagctttgaa
     7981 agcggctggg gtcggtaaag atgacatagt gatttgtcag tccttgacgt tctcagctac
     8041 tgctaatcca attctctatc aaggagctat acctgtattt gttgatagtg attacgaaac
     8101 ttggaatatg aaacctgaac atttgcgaac agcactagaa aaatatccta acacaaaggc
     8161 tgtattagta gtacatttgt acggtttatc agctaattta gacgaaatta ctaaaatatg
     8221 caaagaatac gatgttactc taattgaaga tgctgcagaa tcattaggaa caacatataa
     8281 aggaaaatat actggaacat ttggcgacta tggaatttat tcttttaatg gaaataagat
     8341 aatcacaact tcaggtggcg gaatgcttgt atccaatgac aaagaaaagg tggaaaaagt
     8401 gagattttgg gctacgcaat ctcgtgagaa ggcacgccat tatcaacaca atgaaattgg
     8461 ctataattat cgaatgagca atatcgttgc tggtatcggt cgaggacaat tgaaagtatt
     8521 aaatgaaaga attgagaaaa aacgatatat tcatagtttt tataaaaaag aattgtctaa
     8581 attgtcaaat atacaattca tgccagaaaa taattggaat gaaccgaatt attggttaag
     8641 tgtcataaca ataaagggaa taaatgcgaa tcatcttatt gatgagttag acaaaaataa
     8701 tatagaagcc cgcccagtat ggaaacctat gcatttacaa cctgttttta aaaattatga
     8761 ttatattggc gatgatgtag cagaaacttt atttgactta ggagtatgtt taccatcaga
     8821 tacaaagatg acagatgaag atttaaaata tgtagtatct acgattaaaa gagtgatcaa
     8881 tgatgcgtaa aaaaactttc tatcagcttt ttgggaaaag aattttagat atcctattgt
     8941 caggaattgc tctcatcgtt ttatcgccga taatcttaat tgtaggtttt ttagtaagaa
     9001 ttaaacttgg ttctccaatt atcttcaaac aagaacgacc aggaaaaagt gaaaaaattt
     9061 tttccatgta taaatttcgt acaatgactg acgaaagaga ccacaatgga gaatatttac
     9121 ctgatgaaat tcgactaact aaatttggga aaatgcttag agcaacaagt ctggatgagc
     9181 tacccgaact ttggaatatt ttgaaaggtg atatgtcgat cgtaggacct cgtccattat
     9241 tagtggagta tttgccacta tatagtgaga agcaacggaa aagacacaac gtaagaccag
     9301 gattaactgg actggctcag gtcaatggaa gaaatgctat tagttgggaa gaaaagtttg
     9361 atttagatgt ttattatgtt gataaaatta gtttctttaa tgatcttatt attataattc
     9421 agacatgtaa aaaagtaatc aagaaagaga atattaatac aatcaataac aatatcccag
     9481 aaaaatttaa agggagttaa atacagcagc ttaatgcaag ttttgtgact tgcattatat
     9541 ttaggtataa atcaaagcga gtatattaga attatataac atatgttaaa aaaacgtata
     9601 gctaataaaa gtatgatttt aaaaatttgt gtagagtttt aaatatactg tttcaatacg
     9661 agaaaattat aaaaaagtat aaggaaaaga ga
//
LOCUS       DAXLPC010000095         9654 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.096, whole genome shotgun sequence.
ACCESSION   DAXLPC010000095 DAXLPC010000000
VERSION     DAXLPC010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.096"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            4..2376
                     /locus_tag="ACF3UE_002313"
     CDS             4..2376
                     /locus_tag="ACF3UE_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFD3635683.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTLTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="ACF3UE_002314"
     CDS             2437..3897
                     /locus_tag="ACF3UE_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFD3635684.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKACERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..6112
                     /locus_tag="ACF3UE_002315"
     CDS             3908..6112
                     /locus_tag="ACF3UE_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HFD3635685.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            6128..6277
                     /locus_tag="ACF3UE_002316"
     CDS             6128..6277
                     /locus_tag="ACF3UE_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635686.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6353..6946
                     /locus_tag="ACF3UE_002317"
     CDS             6353..6946
                     /locus_tag="ACF3UE_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFD3635687.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6959..7858
                     /locus_tag="ACF3UE_002318"
     CDS             6959..7858
                     /locus_tag="ACF3UE_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFD3635688.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7861..8346
                     /gene="ssb"
                     /locus_tag="ACF3UE_002319"
     CDS             7861..8346
                     /gene="ssb"
                     /locus_tag="ACF3UE_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFD3635689.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSSSPSPTTFEQRDVATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            complement(8487..8591)
                     /locus_tag="ACF3UE_002320"
     CDS             complement(8487..8591)
                     /locus_tag="ACF3UE_002320"
                     /inference="COORDINATES: protein motif:HMM:NF028245.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HFD3635690.1"
                     /translation="MPVETALGLMISFGSLIATIIFGILAVVNNNQKK"
     gene            8765..9025
                     /locus_tag="ACF3UE_002321"
     CDS             8765..9025
                     /locus_tag="ACF3UE_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635691.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            9462..>9654
                     /locus_tag="ACF3UE_002322"
     CDS             9462..>9654
                     /locus_tag="ACF3UE_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFD3635692.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYVLIDEK"
BASE COUNT         3635 a         1640 c         2011 g         2368 t
ORIGIN      
        1 gacatggcag aagaaaaaga accactagac aatagtcgct tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaacgaa caaattgaga agatgtttga acaccagaga
      121 aagaccaacg gtcagccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gaacgtttag aaaacaaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcggc
      301 ctggatatga caatcgaaaa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgctacgatc cgaaaatacc aacggaaatt ggaaacatta
      421 gaacagctga aagaaagatc agaaaaagga aaagaaaatc ttcttcctga agtacaagca
      481 attattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 gactatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctgcg
      661 ccaactgatt ctttgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt agaattgatc
      781 gatcaactca aaacgttgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaacccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgaa
      961 aaggaacaaa aacaaacggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taagcaagaa
     1081 gtcaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtgaaag aacttttgaa ttttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc tgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctacacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacggggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cttacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac ttcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagcg
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tgtagaaacg gcagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtgat tttaaaagga
     2221 aaaagttatg gaaaagagat tcaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga aacagtgtca gaagtggcca aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgc gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt ttgaaaatga ccgaaaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac tctaagcaac aatttaaagc agccacagat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtagaaa atcttcattt tgagacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaaca tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaatg agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagttaaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac taaatcgtga tcagttaaac
     3181 gatacgtggt tagtttcgat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagttgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aagtcattta tgaagaagtc gcaaaagaag aaaagatcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaatt ggtttccgct
     3541 cacaaagtaa atgcgtcttt tggtcagcag ctttctgtta acgattcaat agaagctatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagcttgtga acgcgtggat
     3661 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc tcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     3781 cctgaagtaa aaaaggattg gaatgatcaa ttgaagcatg aaatctacca acaagagatc
     3841 agaaagcaaa aacgtgccat gttgtttcaa caaggtagac agcaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaaaccgtca caagcgaagg cttatgccga
     3961 tagcttttct aaagctaccc gaaaagatgg gtattttgag atccaagatc gattgttttc
     4021 aggagaaact gtgatcacgt atggttttgg tcatttagtc gagttagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agagcatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatagcttg
     4261 gacgatcatt caacaagcag gcgccgatca tggaaagata tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagatg cagaagagac
     4381 ctacccaaaa tttgaagaag cacaagcacg ccagatcgcc gattggttga tcggcatgaa
     4441 cggtagcccg ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gtttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttacaggaaa agattagaaa
     4561 cttccaaaaa gaaccatatt ttgaaggaaa agcccaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggtacg atccaccaag ttgaaaccga
     4741 gaaaaaaagt gcggcaagtc cacgtctttt ttctctatcc agccttcaat ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagatac tttggaagcc atgcaagggt tgtatgaagg
     4861 gaaatatcta agctacccac gaacagatac cccttatatt acagaagggg agtatgcgta
     4921 tctgttggat cacttagacg aatacaaaca ctttttaaag gccgaagcca ttcctactcc
     4981 tattcataca ccgaatagtc gatatgtgaa taataagaaa gtccaggaac attacgcgat
     5041 cattcctaca aagacggtca tgacggcagc ggcttttgaa caattaagtc cactgcagca
     5101 ggctatttat gaacaagtgt taaaaacaac ggtggccatg tttgcggaaa agtataccta
     5161 tgaagaaaca acgatcttga cgcaagttca gcagcttcag ctaaagacag tcggaaaagt
     5221 accagtagat ctaggttgga aaaagctgtt tggcaaagag agcgacagaa aagaaaagga
     5281 agaagaaccg ctacttccta aagtgacaaa aggagaagcg gtgacggtag atctacaagt
     5341 ccttgaaaaa gaaacgaagc caccacaacc ttataccgaa ggtacgttga tcacagcgat
     5401 gaaaacagct ggaaaaaccg tggatagcga agaagcacaa tccatattga aagaagtaga
     5461 aggaatcggt acagaagcaa cacgagcaaa tattattgaa actttgaaac aaaaggaata
     5521 tatcaaggta gaaaaaaata agcttgtggt gacaaataaa gggattttac tttgccaagc
     5581 cgtggaaaaa gagccgctgc taacaagtgc cgaaatgacc gccaaatggg aaagttactt
     5641 attaaagatt ggtgagcaga aaggaacaca agctactttc ttagctaata tccaaaaatt
     5701 tgtctctcac ttgttggaag tcgtaccggg acaaatccag tcaacagatt ttggatcaac
     5761 gttacaagag gtgaaagcag ccagtgaaaa acaggaagca acgcgtcatt taggtgtttg
     5821 tccaaaatgt cgggaacaag aagtcttgct ttatcaaaat gtggcggcat gtacgtctga
     5881 agcctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag ccacacaact
     5941 gaaagagatc attcaaaacg gccgaacaag ccaatcagtc agaggactaa aaggtcagaa
     6001 aggttcgttt gaagcaacga tcgttttaaa agaagacttt acaacaggct ttgaattttc
     6061 tgaaaagaaa aaaacgaact ataagaaaag aacacgccgc actacaaaat aatgaagggg
     6121 ttatcctatg cgaaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagcaaaaat
     6181 tcgtttagaa caagagaaat tacgtgcaaa taaaagaaga ctgcaacaat taaagaacca
     6241 gcagcgcatt caaaaagaaa tcgaattaga tcgatagacg ttaatcttgt tacaaataaa
     6301 ctactatgat atatttgatg tagtgtattt gtaacgaagg gaggggaagt aaatgcaaga
     6361 taaactgaaa gaattgttgg ctattcgcga tggaaattta tctatgaagg aagccaggaa
     6421 atttggaatc gcagcaacca ctgtacaaag attggtgaat caaggaaaat tgatcaaagt
     6481 tgatcgtggt tattatgtag aggatggtca tggaatagat gatttatttt ggcttcagca
     6541 acgattttcc aggggaatct tctctcatga aacgacttta gatatttacc agctttctac
     6601 gaatatgccg aaattcattc acttaacttt tccccatggc tataacgttg atcgttcaat
     6661 tacaaaagag cagcagttac aatttcattt cgtgaagaaa gaagtttatg aactaggaaa
     6721 agtagaggga acttcctttc aaggaaatcc tattactatg tatgataaag agcgtacact
     6781 ttgtgatatt tggaatccga gatatgaatt tgaatatgaa atgaaattag aagcattaaa
     6841 agagtacatg gaagacccat tgagagatcc aagtaaatta agagattaca tgacaaaact
     6901 acatgtagaa aaagaaatga aataccacat gcaaagctta tattgatgga ggaaaaagat
     6961 gacaccgaca caatttgcag caaaaacaag aaatttagca aagagtacag gattaaatgc
     7021 acagttagtg caacggcatt ttatgatgga tcgtctaatt gaacaaattt ctgaatcaaa
     7081 gtacaaaaat gacttcattt tgaaaggcgg ctttttatta ggatcaaaat atggaatcga
     7141 tagaaggaca acaattgata tcgatacgac atttagaaat agcaaattaa ctgaagaaaa
     7201 attgaagagc atttttaatg atttaactag aaaacccaca aaagaaggca ttgttttctc
     7261 tattcaagga atgaaggaaa caagagaagc cgatttttat cctggatttc aaattaaatt
     7321 ggtggctaat ttagagaaag tacgtgtacc gtttaaaatg gacgtgacaa caggagattc
     7381 tatttatcct gaagtagata cacactatca ccaattaatg tttgaagata aaaaagtgga
     7441 gattccagct tatccaacag aacaaattat tgcagaaaag ctaagtgcta cgttcagctt
     7501 tggcacagat aattcgagag caaaagatta ctacgactta tttaccattc cgaaactaga
     7561 aaatatcgat acgaaagagt tatacaaaag tgttcgaaat acatttacaa aacgtgggga
     7621 tacaaaaccg ttgtcctttt attatgaaag agaaatggat aagatcagag gaaatgacta
     7681 tttggaaaag cagtgggaaa aatatcgctc agttaacacg tttgcgaatt ccatttcatt
     7741 tacagataca gtcaacgaaa ttgatcacct aatgaaaagt gtgatcaaaa ttgaaaatca
     7801 agaaagaaaa cggcagttta aaagatcaca acaaatgaat caagaaatgg agagataaag
     7861 atgatcaata atgtaacttt agtaggacgc ttaaccaaag atccagattt acgttatacc
     7921 gcgagtggta ctgcagtagc gacttttacc ctagctgtca accgaaattt cacgaatcaa
     7981 aacggcaatc gagaagctga ttttattaac tgtgtgattt ggcgcaaacc agcagaaacg
     8041 atggcgacat tagctaaaaa gggcagtttg atcggcgttg ttggacggat tcaaacccga
     8101 acctacgata accaacaagg acaacgtgtg tatgtgacag aagttgtggc cgataatttc
     8161 caactattag aaagtaaagc agcgacagaa agccgtgcgc acgctgatca atcgtccagc
     8221 agtccaagcc ctaccacctt tgaacaacgg gatgtagcta cgcctaacaa caatggattg
     8281 aacgcttcac aaaatccatt tggcggacaa tcaatcgata ttagtgatga tgatttacca
     8341 ttctgattgt aaaagatcaa taaagttgtt ataatggata cgaaaagagg agttgcgcta
     8401 acaactcccc taacagcacc gtttaagacg gtgaccagct taatattatt tttgaaaaat
     8461 aatcgtcgac cggctaaagc tgacggttat tttttttgat tgttgtttac aactgctaag
     8521 attccaaaaa tgattgttgc gatcaaagaa ccgaaactaa tcattaatcc tagcgccgtt
     8581 tcaacaggca aaaggcttct cctttctgta agattttgga agtacgcaca tacgcaccac
     8641 ctcactttca atcggatagc caccgtcaca aactttactg tcttgatcat tatagcatat
     8701 ctaaaatcga ataaaaattc tcaattttag ctgtttttgc tataatttta gcgaggtgat
     8761 cgtgatgaac aaatatgttg gtttgcttga taaaatccga gtaataaaaa cacaaccatt
     8821 attggttcgc tttactttac aaacaattca tgaatcgatt aattgtgtag ttgcagatat
     8881 tgaaattatc gataaattgt taattatgga tgatggaaaa tacaatattg ccgtcacagg
     8941 tcatttcaat aaacggaatc aattagtcat tgaatcgatg caaattagaa accccgatca
     9001 ttttacgcga tcgatgggca tataaaagaa gagctgcagt cctaaatgag gattgcagct
     9061 ctttttgttt tacatagaaa caggaaaaga cctttttagg aagacacaag tgccttctca
     9121 attgaaaaac ctttctctca ctccaaccgc caccgccgtt cgagaagaaa ggaagtgaac
     9181 gttgcacgtt cactaagata tggtgtcttg caaagcaaga caaaatagaa aaaacttcct
     9241 ctcaccaaaa ggttcgttcc tgttcgctat ctctttattg atttgccaga ccggcaacaa
     9301 gttgcctttt atcaccaaaa agcgacaagg acaagggtaa atggcacgct gcgcgccctt
     9361 gtccttgtcg cttttcgttg attcattctg gccaacaaat caataaagaa agaactaacg
     9421 aaaggaaata aaacctttcc taagaggagg cagaatcaat catgcgaaag aaatttgatt
     9481 attggggtgt tcccttcagc gaattattcc caaactatca tgcaccacat actgtcgaat
     9541 gcgattgtgg agaaagagcg aaatgtatca aaagctatcg tttgtatcaa tgtccaacat
     9601 gcgggaaaaa atataccttg tcttatggcg attatgtttt gattgatgag aaag
//
LOCUS       DAXLPC010000096         9413 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.097, whole genome shotgun sequence.
ACCESSION   DAXLPC010000096 DAXLPC010000000
VERSION     DAXLPC010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.097"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            236..1042
                     /locus_tag="ACF3UE_002323"
     CDS             236..1042
                     /locus_tag="ACF3UE_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3635693.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            1054..2274
                     /locus_tag="ACF3UE_002324"
     CDS             1054..2274
                     /locus_tag="ACF3UE_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635694.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     NKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            2264..3850
                     /locus_tag="ACF3UE_002325"
     CDS             2264..3850
                     /locus_tag="ACF3UE_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3635695.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVVQTSIAQPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSEAT
                     ERMVFRFAQQPSFIEFSAEAAGEKLIFIDSNAVVKTVNDCYLFDGKEIPEFALTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENQHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKKTSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSRDEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            3889..6027
                     /locus_tag="ACF3UE_002326"
     CDS             3889..6027
                     /locus_tag="ACF3UE_002326"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3635696.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKIRLSGKMRGKAILDFQTAKHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKTIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNIHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKKLGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            6315..7706
                     /locus_tag="ACF3UE_002327"
     CDS             6315..7706
                     /locus_tag="ACF3UE_002327"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFD3635697.1"
                     /translation="MNKNGEWNAARRIFIIIMDVLVLNVSIYLSFLLKFQGEVPARNL
                     ETFQHSAVFISIIFIALNILLGAYVFYSRVISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVIVLSFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVVIDKYYENTKKLIDDIDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFKIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSVTAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENIRS
                     LAEIDFSQEKIYR"
     gene            7765..8574
                     /locus_tag="ACF3UE_002328"
     CDS             7765..8574
                     /locus_tag="ACF3UE_002328"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3635698.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFNHMTVMFD
                     KNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYARRGGSKYL
                     LPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN"
     gene            8546..>9413
                     /locus_tag="ACF3UE_002329"
     CDS             8546..>9413
                     /locus_tag="ACF3UE_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3635699.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLKRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNCGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNYPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNKFFKRELFNHIVFPENKLYEDMVPMYEAFRAASKIDILPFSGIFYYQNNDSI
                     VYQSFNSKQYDNILQRKILVDEVKKDYPRLINLANARLVDGYLSTGFKITGKNQNQKE
                     KQKYYNQSKREIK"
BASE COUNT         3250 a         1443 c         1898 g         2822 t
ORIGIN      
        1 aaacgaagaa aaagtgttag tagaaaatcg ccttcgattt tccaccaaca caaaatatta
       61 tagaacccct tttttggttt attgcaattg tctagcatct tctgtaaaat agaaacgtta
      121 gagaaaatct tgtatcatag aaaattaaga aagaaataag aacgcagctc ggtaccaaaa
      181 atatggtaaa atggcacttg actgtaattc actgaaatcg cttggaggaa cacaaatgtt
      241 taaagatttg tatttattta tgaaagacat ttatcagaat agaaaattac tgctacagtt
      301 ttcgatcaat gacttcaaat caagatatgc aggatcgttt ttaggaatct tatgggcgtt
      361 tatcaatccg ctatttactg tattgattta ttggctggta tttggtgttg gactgaaagc
      421 acaaatgatc gatgcaaaat acccatttat cgtatattta gttaccggga tgattccctg
      481 gttcttcttc tcagatgcat ttgcatcaac tacggttgtt tttcgggaat atacttattt
      541 agtaaagaaa gtcgtattca atattcgtat cttgcccacg acgaaaatcc tatccaatct
      601 gtacacccat ttattcttca ttctgattgg catagctgtc gcgcttataa atggtatata
      661 tccttcagca atgtctttac agctgattta ttatttattt tgcatgtgtg ctttcttgac
      721 aggattgact tggctgacgg catcgatcca accattttta cctgatatca tgcaattaat
      781 tacgatcgtg ctgcagttga tcatgtggac attaccgata ttatggagcc ctaatcagtt
      841 tgattcaggt cttgtaagca tattgaaatt aaatccgctg tactatgttg ttcaaggtta
      901 tcgtgagtca tttttaagtg aagcttggtt ctgggagcat ggaacatata ctttgtattt
      961 ctgggttttc acgttagtaa tgttcgtaat cggctctgca gtgttccgta gattgaaacc
     1021 acatttttca gatgtgctgt aaggagaata gctatgacag aatatgcaat tagactaaaa
     1081 gatatcacaa aatcttataa tatgtacgca aaaccttcgg atcgatttcg tgaagccctc
     1141 aatcctttta agaaatccta tcatgatgta ttttatgcgt tgaaaaacgt gaatgtagaa
     1201 ataaaaaaag gtgagatgat cggtttcgtg ggagaaaacg gatcgggaaa atctacaatg
     1261 ttgaaaatca ttacgggagt actgacacca acatccggca cgatggaaat cgaaggaaaa
     1321 atctcagctt tgctagaact aggatcagga ttcaatcctg agtattctgg ctatgaaaat
     1381 atctatttaa atggaatggt tctaggattt tcaagagaag aagtcgatga aatggtcgat
     1441 gatatcattg aatttgctga tattggcgac catatttatc aacctgtaaa aacctattca
     1501 agtgggatgt tcgttcgtct agcttttgct gtagcgatca atgtgaatcc tgatattttg
     1561 attgtggatg aagcattggc agtaggagat cttgaattcc aactgaaatg tatggaaaaa
     1621 tttacagaaa ttaagaactc gggaaaaacg attttattcg tttctcatga tattagttcg
     1681 attcgccgtt tttgtgatcg ttcctattgg ttgaaaaatg gagaagttgt cgaatatggt
     1741 gatacgatgg aagtaacgac gaattacgaa aactttttga agaaaaaatc agttaaaaca
     1801 gtagatcgaa ataaaaacca agtagaacgc ttcgcagctc cagatatcgt agacgtgacg
     1861 aaagccgaat tgttggataa aaataaaaat ccagtggata tgctggaaca aggagaaaaa
     1921 ctatacgtta aagtaaccta tgaagtaaaa gacgatacaa tcaaaaatcc agttttagga
     1981 attgctctgc gtacagtcga caatttttat gtgtgcggac tcaatactct actagatggt
     2041 atcaagatcc cttggaaaaa aggtgagaat atcttttatc tggagtatga aaagttaggt
     2101 ttgttagctg gtgaatatta ttttgacgtt gcggtctttg aagaaaatgc aacggttcct
     2161 ttggtataca agacaaaata catgaacttg tttgtcagcg gttcttatat cggagaaggc
     2221 atcgtggtct tagaccataa atgggaagaa gggactcata gcaatgaaat atgattttga
     2281 aatggaccta gatgaacaaa gcagtgtggg aaaaattgcc gcacagatca aaccaggaag
     2341 taaagtttta gagtttggtc ccggaaacgg tcgattaacg aaacatttga tcggagcaaa
     2401 acaatgtgaa gtgagcattg ttgagctaga taaggaatta ttcgattttg tcagcgaatt
     2461 tgcccaagat ggattttatg gagatatcga aagttttgaa tgggcaaact attatgctgg
     2521 acagacattt gattacgtct tgtttgcgga tgttttagaa catttagtag atcctggaaa
     2581 aacattgaag aaagtcagag aatttttgaa tgaagaagga gagatcctga ttacattccc
     2641 taacttagca cataattctg tcatgatcga tttgttcaat aatcaattgc cttgggcttc
     2701 ttatggtctc ctagatgaaa cccataattc tttttatact catgatggtt tccaaaaagt
     2761 ttttgaaaaa gccggattat tcattaatat tgaagattac ttgtacttgg ctgtaggaga
     2821 tacagaatta aaatcaactt atgaagagtt gccggaagct gtacgctatg atttcaaaat
     2881 gcgaccattt ggtgaagtct accaatactt tttctcattg atgaaacatc cagtagtaca
     2941 aacttccatt gcacagccac aaaactctaa ttatgtaaaa gtactagaag taacccagca
     3001 aacgaaacaa gatgaaacaa tccaacaaat accattcaat aatttcacag gggaaaatga
     3061 gacactaagt ttccccgtgt cagaagcaac agaaagaatg gtgtttcgct tcgcacagca
     3121 acctagcttt atcgaattca gtgcagaagc tgctggagaa aaactcatat ttatcgattc
     3181 aaatgctgta gtcaaaacag taaatgattg ttatttgttt gatgggaaag aaataccaga
     3241 gttcgctcta acggatattt ctgggaaaga agtgactatc cattgtcact atcgctttat
     3301 cggggaattg acaccaacaa tgaaagaatt gctggaaaca attcgtccta tggctgaagt
     3361 cacaaagcag ctttctgaga aaaatgatga attagaaaga gaaaatcagc atcttcttga
     3421 ggaaaataca agactagacc atacgttaaa aacaaccaca aatcgctatt gcacattgtt
     3481 ggaaagtgat gaatggacga tcaaacatag actaggacga cgtaagaaaa aaacatcgaa
     3541 aaaaatacaa gaaaaagagc tttctatatg tattgatgag aaaatatggg atgcagaaac
     3601 aaaaatatta aaaatcatcg gatggggaat cgctaattcg gatcgccagc cattgtccta
     3661 taagttatca gctgaccaat cgccattttt cgaagcaatt cctgtttcac gagatgaagt
     3721 caatcaagca gaacagctcg caaaaggaac agaagcggga tttgaattac gaatcctttg
     3781 cgagcaagaa cgttcattct tagtggaagc agtagctcaa aatggtcaat catggatcat
     3841 tgaaatgtaa ataatgatta acttataaag ataaggagta aacgaatcgt gcaaaaaaaa
     3901 gaaattgccg tatttatcga tcaaatcact cgtgaacggg ccactggcga tttgcttatt
     3961 gtgggctggg caattgatga agtgaccaaa gaaatcccta cgataaaggt agaaaaagaa
     4021 aatgtgattg ctgaagcaac acatgtcgta agattggata tcaatcattt atataatctt
     4081 gatgttaaga cccaaagcgg ttttaagata cgtttatccg ggaaaatgag aggaaaagcg
     4141 atcttagatt ttcaaacggc aaaacatcaa aatggcatag ctgtgaaact aaatggtaaa
     4201 tacccttatg atgacggcat tgaatcttca tgggaaagaa aaaaaagatt actgaaaaaa
     4261 gggataaatt atgcaaggac tcatggcgta aaaaaaacaa tccgccgggt caaactggaa
     4321 ttgaaaccag gatcgatcga ctatgcagag tggatcagtc gtcacgagaa acctgatctg
     4381 aaagagcaaa ggaaagaagc acaagggttt gcataccgtc cattgatttc catacttatg
     4441 cctgtctata acgttgaaat caaatggctc gaaaaatgca ttgattcggt attggatcaa
     4501 acgtatgatc actgggaact atgtatcagt gatgatgctt ctactgatcc agctatccga
     4561 aagtgtctgg aatcctatca agcaaaggat gatagaatca aagttgtttt ccgacaagaa
     4621 aatggacata tcagtctggc aactaattct gcgttggaaa tggcagaagg agaatttata
     4681 gcgctcttag ataatgatga tgaattaccg ccatttgcat tatatgaagt ggcaaaagtg
     4741 ctaaacatac atccagaact ggatttgatc tacagtgacg aagataaaat cgatgcagat
     4801 ggcaatcgct ttgatccgca cttcaaagca gactggtctc ccgatacatt gatgggaaat
     4861 aattatatct ctcacttagg cgtatatcga acaagtattg tgaaaaagct tggcggtttc
     4921 cgtaaaggct acgaaggctc tcaagattat gatttggtcc ttcgtgtgac agaacaaatc
     4981 cctgcagatc atatttacca tattgaccga gtcttgtatc attggcggac gatcccagga
     5041 tcaaccgcaa gtaatggtga agccaaaagt tatatctatg attctggagt gaaagcattg
     5101 acagatgccc tgtctagaag gaatatcaaa ggaagcgtac gtcctggcag aatttctgga
     5161 ttttatgaga ttgcttatga cgtcttgcaa gaggatttgg tcagcgtgat cattccaacg
     5221 aagaatggct atgaagatct aaaaacttgt gtggattcga ttatcgaaaa aacgtcttat
     5281 ccaaattatg aaatcattat tgcagataat ggaagtacag atcctaaaat gcaggaatta
     5341 tttgcagaat acaagcatca gctgaaagac cgatttatcg ttgaattaat tgacattcca
     5401 ttcaattatt cacgtatcaa caatctggca gcagaaaaag caaacggcaa atacttttta
     5461 ttcttgaata acgatacaga agtgattgaa cctgactgga tgacagcgat ggtttcttat
     5521 gcacagtttg atcgaatcgg ctgtgtagga gcaaaactgt tttatccaga tgatacaacg
     5581 cagcatgcag gagtattatt aggaatcggt ggtgttgcag gacatgcatt gaataactat
     5641 gatcgaacac attgtggtta tttcggccga ttggtcattg acgtcaatta cttagcagtc
     5701 actgcagctt gtatgatggt caaggcagct gacttcaatg ctgtcaatgg atttgatgaa
     5761 acattagaag tagcattcaa tgatgttgac ttgtgtttga aagtttatga actgggtcgt
     5821 tacaatgtct atgcacatca agcagaattg tatcatttcg aatctaaatc aagaggttat
     5881 gaagatacac cagaaaaaca aagacgtttt gccggggaaa taaaaaaaat gcaagataag
     5941 tggccttctt atattgctca tgacccattt tataacgata atctaactaa agaaggaatc
     6001 ggcgattttt cattgagacc tgattgatta aaagaactgt attttcattt ttattgatga
     6061 aaatacagtt tttttagtat atgaaaattg taacttgtga ccgaagagat gataggaaga
     6121 acacccattc agtaggaaga atgtgatacg atttttgtcc aactctctgt taggcagaaa
     6181 tatacatata aacatacaat agtcaccttt tctagtttct tttaatttat tttacaattt
     6241 ggttattcac taggttttta aactttgcta tggtaagatg atagaggcat tattttatgg
     6301 ttaggagtgt atatatgaat aaaaatgggg agtggaatgc ggcacgtagg atattcatta
     6361 tcatcatgga tgtacttgta ttgaatgtgt cgatctatct tagctttttg ctgaagttcc
     6421 aaggagaagt cccagcaaga aacttagaga cctttcagca ttcagcagtt tttatttcca
     6481 ttatctttat tgcgttgaat attttgttag gagcttatgt attctatagc cgagtgatca
     6541 gtgatatcgt cttcattact gttattggac aggtgctgat agcattgggg atcatggtag
     6601 ttacttttgc tggacgttgg tttgcatttc cgcgtggcgt catcgtgctc tcgtttatac
     6661 ttggcacgat attacttagc gtttatcgga tagttgttta taaactatac ttaagagtca
     6721 gtcgtgataa gaaagtcctt atcgtaggtt tggagaaaga tgtcgcacca gctatccaaa
     6781 actttcaatc taagaaaaac aacaaacata aagttgaagc agtagtgatc gacaagtatt
     6841 acgaaaacac aaaaaaattg attgatgata tcgatattgt ctacttggct tctaaaatcc
     6901 cagaagacga aaaaatcaat atttatcaat tagtaactaa aaaagagaag aagctatttt
     6961 taaatacaac ttttgaaaat ttaacgatga tcaatccgaa catcatgaat ttcgaagatg
     7021 aaagtatcat tgaagcttcc ggtttcaaaa ttcagccgga atatgaatta ttcaaacgtc
     7081 tttttgatat catcgtttcg cttattttac tgattcttgc ttcacctttt atgctaatca
     7141 cagcgatttt ggtaaaaaca acttcacctg gaccaattat ttataaacaa gtacgtatta
     7201 cgaaaaatca aaaggaattt tcaatctata aatttcgttc catgagtgta acagctgaag
     7261 caaaatcagg accggtcttg gcaaagagca atgatgcacg tgtgacacca gtaggcaaat
     7321 ttatccgtgc cgtacgtttt gacgaattac ctcaaatctt taatgtattg aaaggcgata
     7381 tgtcgatcgt cggaccacgt ccagaaagac catttttcgt tgatcagttc aatgaagaaa
     7441 atccttatta ttatttaaga cacaatgtac gtgcagggat taccggatat gcacaagtat
     7501 acggaaaata tgtatcagat tataatagta aactacgttt tgatttgttg tatatcaaaa
     7561 agtattcctt actattagat ttgaagattt tacttcaaac aatcaaaatc ttatttgata
     7621 agatgtcctc acaaggacta gatgaagatg aaaatatccg ttcgttagca gaaatcgact
     7681 tttcacaaga gaaaatttat cgctagatgg gaaaaatttt gagcaaagaa gtaggagaga
     7741 acattggaaa ataaaaatat aagtatgctg ctttctttat atgataaaga aaaaccagag
     7801 tatttaaagg aagcattaac tagtattttt gagcaaacag taatgccaaa agaaattgta
     7861 ttagtttatg acggccctat aaatgaaaaa cttcaagtag ttgtcactta tttccaacaa
     7921 aaagatcctc acttgtttac agttgtaaaa ttagaaaaaa atcaaggatt ggggattgct
     7981 ttagcaattg gattagaaca tacgaaaaat cgcttagtag ccagaatgga tacagatgat
     8041 atcatggaac cccaacgatt agaaaaacaa ttagagatct tccaaaaaga tccagaaata
     8101 gcgattgttg ggagtaatat tgaggaattt actggcacgc ttagcaatgt tatcggaaga
     8161 aggattgtac ctgaatataa tgatgaaatc cgtgtgtttt cgaaaagaag aaatcccttt
     8221 aatcatatga cagtcatgtt tgataaaaat gctattttag aagtgggaaa ctatcgccca
     8281 ttaattggat ttgaagatta ttatttgtgg gtaagactgt tgaaggcggg atataaaggg
     8341 tataatatcc aagagattct agtccatgct agagcaggtg ctgacatgta tgctagacgt
     8401 ggaggaagta aatatctttt accaggaatt aaaggccgat atcgcgtatg gaaagatggt
     8461 ctaggatcac taaaagattt tctgatagtt atttgcggac atcttgtaat tagtttatta
     8521 ccgaataaaa ttaggggaaa agtatatgaa tcaaaactta gaaaaacaaa ctaaactttc
     8581 tataatcata cctttttaca atgcaaaaaa tactttaaaa agagctgtag acagcgtctt
     8641 aacgcaaggt tatcccaata ttgaaatctt gttaattgat gatggatcta cagatggtag
     8701 tagtgacatt ggtgacgaaa ttgctaatct agagagtaaa gtagcatgtt atcacttgga
     8761 aaacgctggt ccatcagttg ctaggaattg tgggataaaa gaagcaactg gaaatttggt
     8821 aggattttta gatagtgacg attatttttt acctgattgt tttaataatg ttttgaaaga
     8881 ctaccatagg aattaccccg atatcattgc ttttggatta agtaaaggaa aaaatataga
     8941 aaatgcaaat ttatttgttc ccgaaaagaa gattggttgt tcaagtgaag aagcaattga
     9001 gcaaatgttt agaagtaagg cagtggattt ttacgtatgg aataaatttt ttaaaaggga
     9061 attattcaat catatagttt ttccagaaaa taaattatat gaggatatgg ttcctatgta
     9121 tgaagctttt agagcggcta gtaaaattga tattttgcca ttttcaggta ttttttatta
     9181 tcaaaataat gatagcatcg tttatcagtc ttttaattca aaacagtatg ataatatttt
     9241 gcaaagaaaa atattagttg atgaagtaaa gaaagattat cctcgactta ttaatttggc
     9301 caatgctcga ttagtagacg gatacctttc aacagggttt aaaattactg gcaagaatca
     9361 aaatcagaaa gaaaagcaaa aatattataa tcagtctaaa agagaaataa aaa
//
LOCUS       DAXLPC010000097         9282 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.098, whole genome shotgun sequence.
ACCESSION   DAXLPC010000097 DAXLPC010000000
VERSION     DAXLPC010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.098"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..435
                     /locus_tag="ACF3UE_002330"
     CDS             <1..435
                     /locus_tag="ACF3UE_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFD3635700.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="ACF3UE_002331"
     tRNA            complement(759..842)
                     /locus_tag="ACF3UE_002331"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="ACF3UE_002332"
     CDS             1370..1870
                     /locus_tag="ACF3UE_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3635701.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(2060..2404)
                     /locus_tag="ACF3UE_002333"
     CDS             complement(2060..2404)
                     /locus_tag="ACF3UE_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFD3635702.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(2558..3478)
                     /locus_tag="ACF3UE_002334"
     CDS             complement(2558..3478)
                     /locus_tag="ACF3UE_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFD3635703.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            3665..4156
                     /locus_tag="ACF3UE_002335"
     CDS             3665..4156
                     /locus_tag="ACF3UE_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFD3635704.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(4180..6555)
                     /locus_tag="ACF3UE_002336"
     CDS             complement(4180..6555)
                     /locus_tag="ACF3UE_002336"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFD3635705.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            6881..7507
                     /locus_tag="ACF3UE_002337"
     CDS             6881..7507
                     /locus_tag="ACF3UE_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD3635706.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            7530..8234
                     /locus_tag="ACF3UE_002338"
     CDS             7530..8234
                     /locus_tag="ACF3UE_002338"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD3635707.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            8426..9259
                     /locus_tag="ACF3UE_002339"
     CDS             8426..9259
                     /locus_tag="ACF3UE_002339"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFD3635708.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
BASE COUNT         2829 a         1791 c         1651 g         3011 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat ttaattaact tataatatag cagacaaaat tttataaaca aagaaacctt
     1981 ttatctcttt tcttctagaa aggataaaag gcttttttgt ttttcctatt tgcttctcat
     2041 agctagtcag ccaagatttc tatcgtatcc ccaacgcaat ccgtgcataa cggctcatct
     2101 tatctgtcgt ccatgctgga taccagacta gtttgacttc tgctttcgtt acttctggca
     2161 cttcttttaa tgcgtcatgg atagattctg ttaaaatatc tgctaatgga cagcccatag
     2221 ttgttagagt catcttaatg actgtttctc cattttcagg attgaattct atatcataaa
     2281 tcaagcctaa attgacgatg tcgattccta attcaggatc aatcaccatt tccaaggcag
     2341 caagaatacg ttctttgatt agttctattt cttgtccaga ccgttcttgg tttgcttcgc
     2401 tcatcgtacg acactcctta acacgatttt tatttatcat actctttttt tagctgcttg
     2461 taaatgagaa tttagaagta agattctcgt ttaaatttat aaaaatgttc ttattagatg
     2521 taatagatta aatttattct aaaataaacc tgattcctca ttttttttgt gaacgatttt
     2581 ttatttctgg caatacgcca gttgttcgat acattttttg ttcgttttca tttgcaaacc
     2641 ggccaaatac tgaatgagtt ggtaaaatat tgataaatgc atcgtcgtcg atttcatgaa
     2701 cgatctgatc aagatcatac atttcgtagc gggtgatgac catcatgatc atgttccctt
     2761 gtttttttga atagccaccg acagacggca gtaatgtcat tccacgtacc atccgttttg
     2821 ctagttcttc tgttacctct tctggcttga cggtaacgat cattgctgtt actttttgat
     2881 gactcgtgtg gatggcatca attacttgag tcattgcata aatggaaata atcgtataca
     2941 aggcactttc ccagttaaag aagaagcctg cgatgactac aatgatacca tttagaatca
     3001 gcatgtagtt tccgactgtt tttccagttg tttgtgaaag tacaagagag atgatatcca
     3061 tcccaccagt tgtaaagccc atttttaaag ataatcctac gccaagacct aataaaacac
     3121 cgcctactag ggcattcatc aaaatattat cagtgatctg tccgactgga agcagcatcg
     3181 tcatcaccga tacacataca acattcacaa aactaaggat cgttgctcgt tttcctactt
     3241 tgagaaaccc taatacaaac acagggatat tcaaaagaaa aataaatgtt cctgtgtcta
     3301 tcttgatatg aaaccattca tataaaagcg aggaaatgat ttgagcgatc ccattcatcc
     3361 ctgcagaaaa gacattggct ggaatcaaaa aataatttaa agcgaccgca gcggtcaatc
     3421 cggttatcaa aataaccact attttcttta atctttcatt tttatgatac gcagtcataa
     3481 ttttactcac aagcacctct cccctacttt ggtattccaa atgtaagaat aacagtttat
     3541 ctattaaaat aaaatacttc gaactcaaat gagaagaatt ttagcaaaca ggtaagaatc
     3601 tgccctaatc ctatgataag atagatgtat ggtaaatatt tatatgtata tcaggagggt
     3661 tcctatggca aaagatgcta gcttcgacat tgtatcagaa gtcaatacag aagaagtaaa
     3721 aaatgcgatt cagcaaacaa caaaagaatt gtccaatcgc tttgacttca aggattctac
     3781 agtagaaatc aaattagaga acagcaatct agttgtattg agcgatgatg atttcaaaat
     3841 cgaacagatc aaagatgtat tatttggtaa gctgatcaaa agaaatgtgc caatcaaaaa
     3901 tatccatttt tccgaatcag aacacgctct aggtggcaaa gctcgacaaa ctgccgattt
     3961 ggtcaacgga atcgatcgtg aaaacgcgaa gaaaatcact acagctatca aaaatgaaaa
     4021 actgaaagta aaagcacaaa tccaagaaga tcagattaga gtgacaggta agaaccgtga
     4081 tgatctacaa gctgtgattg ctttattacg taaacttgac ttaccaatcg agttgcaatt
     4141 cactaactat cgttaatcaa aaaacgaggc tgacgtctgt cattcctcgt ttttttgatt
     4201 tactgcttct tttgataacc aaaaacgctg tattccttct tccaattccc caacacttcg
     4261 tacttctctt gctgtttgcc aatgttgtgg gaataaacgt cgataagaaa aactagaaaa
     4321 tcgttgatct gccaatacaa cgattccttg atccgccatg ccacgaatca ctcgaccacc
     4381 agcttgcaag actttgttca ttccaggaag ctgataagcg taagcaaatc caaggtgttc
     4441 cttctcatca taatatgatt tgatcagttc ctgctcatga ttcatctgcg gcaaacctac
     4501 acctacgatc atactgccga tcaatcggtc ccctctcaaa tcgattcctt ctgaaaaaat
     4561 cccgccaagt acgcaaaatc caatcaatgt ttcagcggga tttgtttgaa attttgttaa
     4621 aaatcgttcg cgttcttcct cattcatgtc cgtttcttgg attagcacat tgctgtcggg
     4681 atattgctgt ctgaatgctt ccaccgcaag atctaaatat tgataagaag gaaagaaaac
     4741 gaaataattc ccgacctttc catcagcaaa agcatgaatc gtctctacta attttgccag
     4801 actgtgttcc ctttttcgat aagtcgtctc taggtaattt gcgatgaaaa cttgctggtt
     4861 tccttctggg aaaggactcg gcagtttgta agccagactt ttttgtcccc ccagtgtttc
     4921 ctgataataa gagagtggtg aaaaactagc agaaaaaaga atactgcttt ttcctttatc
     4981 caacgactgc tcaagaaaca agcttggatc aatacaaaac tcttttacta tcagatcgcg
     5041 atacgttttt tcgactgttg tttcgtagtg atcatcataa aattcactga ccttcaaaaa
     5101 atgaagcaaa tcaaaataat aaggaagcaa ttgttcttgt gatgggtgct caggaaattc
     5161 tgccagccat tctttaattt tttcgcttaa ttgataacct gcctttacta aagattcagc
     5221 cggtgctttt tgatgatgat aatcccaatg atcttctttt gctatttctc ggatcgaatc
     5281 aaattctttt aatagtttgt tgaaacggcg atgaagtttt ttgaattcct ttggtatagc
     5341 ttccttactt cgtttcgttt tttcataaga tagttctgcc gaatacatct ctcgggaacg
     5401 attcaccaaa ttatgtgctt cgtcaatcaa aaacagatag tcctcgtttt tttcatcttc
     5461 aaaaaaacgt cttaaataaa cagttggatc aaataaataa ttgtaatccc caatgattac
     5521 gtcacaccag atactgacat ctaatgatag ttcgaaagga caaagtgtat gctttcttgc
     5581 ataagtttcg atgacttcac gagtgatctg attctcatga ttcaaaagat cccataaacc
     5641 ttcattaatc cgattgtaat aaccattggc atatgggcac tgatctggat tacaggtcgt
     5701 ctcatctaaa aagcagatct tgtctttcgc cgtcaaagtg acacttttta cttcagctcc
     5761 tgtatctttt aatgctgtca tagcatcttc agctacttgt ctagttattg ttttagccgt
     5821 tagataaaag atcttttctc cctcttcttc ccctacagct ttcaaagcgg ggaataacgt
     5881 agagattgtt tttcctgttc cggtaggtgc ttctacaaac aatttctgtt tcgtacggat
     5941 cgttttataa gcagctaccg ctagttcacg ctgacctttc ctatactcat catgggggaa
     6001 tttcaaagcc atcaaagagg cattgcgtac agtgcgccag ttttcttgaa aaacaagcca
     6061 ttctttataa tcttcagtca gctttttaaa aaaagtttct aactgctctc ttgtctgatg
     6121 ttcaaccttt ctcgtgatca cttcttctgc cgtctggaag taagtcaatt gcagatttat
     6181 ttcttgtaaa tcatgttctt gactatagat ataggcatac acccttgctt gatgaaagaa
     6241 aagttccact tgttctggtt ctaaatcttc aaatcgtggt tcggaggttt tgatttcatc
     6301 tatataataa ataccgtctc ttttgaaaat accgtctgca cggccttcaa cgatcaggta
     6361 atattcatct aattgaactg ttgtttttaa aaagacttct ttttcatagt tttctcccgc
     6421 atctttttgg agcttgcggt ggattctcgc tccttctaat gcagtatggt tacttttttt
     6481 acgattgtcg atacttccac gtcgcaaaat aaattctact aagtgccgca cagatatttt
     6541 tgactgtttg atcatttcca ccacctcttt ctctctaaga ttacctgaaa aaacctagtt
     6601 tagcaaaaag agctctcttt ccaaacataa aaaaacaccc tgctgattag gcagggatat
     6661 aggatataga atttggattt ttggatgaat ctaatgtaac aaggacatat taaaatgcta
     6721 tgaaaactta ctttccttct ctttagaata tccaaatact tttcatatag tctgataatt
     6781 cagataagta aagagaaata agtacctgtt tttgtttcct agcaatgaat gcgttatact
     6841 aatggatgaa agaagttttg gctatcaagg aggaatgcac atgcatatcg aaagattaaa
     6901 aacaggaatg attgaagaaa actgttattt ggtctacaac gaagaagcac ttttgatcat
     6961 tgaccctgga gaagatgcgg aacgaatcaa acaagaaatc aaaaaaacaa accaacagcc
     7021 ggtagcgatt ttgcttaccc atactcacta cgatcatatc ggtgcagtgg aacctttacg
     7081 cgcgtattat caaatcccag tttatgtcag cccactagag caaaaatggc taggtgatcc
     7141 gattttgaat ctttctggac tcggtagaca tgatgatatt gctgatgtta ttgtctcgcc
     7201 tgcagaatat gaatttgaaa tgaaaactta tactttagga aacatgtctt ttcgcgtcgt
     7261 ccctacccca gggcattcta taggaagcgt cagctttatt tttgatgatt ttgtcgtttc
     7321 tggcgacgcc ctgtttagag gaagtatcgg tagaaccgat ctgtatacag ggaatttaga
     7381 acaattactt catagtattc ggacccagct gtttgtatta cctgatgaat ttgcagtcta
     7441 tccaggacat ggcgatgcaa cgacgattga acaggaaaaa aggacaaatc cttttttcaa
     7501 tcgttaaaac gacttaggag gagaataaaa tgacagaaac tacactttat atcgtacgac
     7561 acggaaaaac gatgttcaat acaattgaac gagtacaagg ctggtgtgat acacccctca
     7621 caaagcaagg acaagaaggc attcattatt taggtcgcgg gttaaaaaat gtcgactttt
     7681 catttgctta ttctagtgac agtggtcgtg caatcgaaac tgcccgtatt attctaggag
     7741 aacattctaa gggaaaagaa attccttatt ttattgaaaa aaggattaga gaatggtgtt
     7801 tcgggtctct tgaaggtgga tatgacatgg aaatgtgggg tgtgatccct cgtgtattga
     7861 attttaaaac atatgatgaa atgtttacca cagaagtttc ttttgaacaa attgctaatg
     7921 ctgtatacaa cttagatacc gctgggtggg cggaaactta tgaaacattg cgagaccgtg
     7981 tatggacagg atttgaagat atcgcccatc actgcgaaaa aaatggtggt ggaaatgttt
     8041 tagtcgtatc tcatggtttg acgatcgcct ttttgcttaa tctgatcgat cctaaacagc
     8101 ctgttcgtgc tgggctttta aatggcagcg taacaaaggt cacttatgca aacggtcgat
     8161 tttctatcca cggcatcaat gatacgtctt atatcgataa cgggaaaaca catagtcgcg
     8221 actcgtttct ataatgggga tattttaatt tttaccagag aatcataaaa ggcaaagtct
     8281 gaacgagggc tttgtcttct tttttctctt cgtgtactta tctgctttat ttctcaagtt
     8341 tttcttaata ttaaaaaaca gattgggttt ctcaaaaaat aacggtatac tataagatgt
     8401 atcttaattg ggaaggaagg aatttatgtt ttttgcaaat attatcaaag cagtgattct
     8461 cggtattatt gaaggaataa cggaatggct gcccatcagt agtactggtc atttgatcct
     8521 agcagatgaa ttcatcaaac tggatgccag ttcacaattt atgtcgatgt tcaatgtcgt
     8581 tatccaatta ggggcgatct tggctgtcgt cgttctttat tttcacaagt taaacccatt
     8641 ttctccaagt aaatcaacgg tagaaaaaaa agatacgtgg acactttggt ttaaagtgat
     8701 cgttgcttgc ataccagcca tcatcattgg tttgcctttg gatgattggt tagaagcaaa
     8761 tttccacaag ttcttaccag ttgccattgt tttgatcgtt tacggtattg cctttattat
     8821 tgtcgaaaaa cgcaacaaaa acaaaacacc tcgttggact tctctgaatg actttacgta
     8881 ccaagcagct cttcttgttg ggttattcca agtcttggca cttgttcccg gaacatcccg
     8941 ttctggcgca acgatcctag gatctatctt gattggtgct tcgcgttttg tcgctacaga
     9001 gttttcattt ttcttaggga ttcctgtcat gtttggcgca agcggcttga agatcgtcaa
     9061 atatttagct gaagggaatt cattcaaaat ggaagaaact gttgttcttc ttgtaggaac
     9121 attcgtatct tttgtggttt ccgtcttagc tatcaaattc ttactaagct atttgaagaa
     9181 aaacgacttt accgcttttg gctggtatcg tattatcctt ggtatcattt tgattggtta
     9241 ttggtttatt gcaatgtaga aaaaaccaga acacttctct ta
//
LOCUS       DAXLPC010000098         8944 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.099, whole genome shotgun sequence.
ACCESSION   DAXLPC010000098 DAXLPC010000000
VERSION     DAXLPC010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.099"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(15..1154)
                     /locus_tag="ACF3UE_002340"
     CDS             complement(15..1154)
                     /locus_tag="ACF3UE_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFD3635709.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1553..2851)
                     /gene="eno"
                     /locus_tag="ACF3UE_002341"
     CDS             complement(1553..2851)
                     /gene="eno"
                     /locus_tag="ACF3UE_002341"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFD3635710.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(2967..3722)
                     /gene="tpiA"
                     /locus_tag="ACF3UE_002342"
     CDS             complement(2967..3722)
                     /gene="tpiA"
                     /locus_tag="ACF3UE_002342"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFD3635711.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(3826..5016)
                     /gene="pgk"
                     /locus_tag="ACF3UE_002343"
     CDS             complement(3826..5016)
                     /gene="pgk"
                     /locus_tag="ACF3UE_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFD3635712.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(5126..6127)
                     /gene="gap"
                     /locus_tag="ACF3UE_002344"
     CDS             complement(5126..6127)
                     /gene="gap"
                     /locus_tag="ACF3UE_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFD3635713.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(6168..7259)
                     /locus_tag="ACF3UE_002345"
     CDS             complement(6168..7259)
                     /locus_tag="ACF3UE_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFD3635714.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="ACF3UE_002346"
     CDS             complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="ACF3UE_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFD3635715.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            8802..8873
                     /locus_tag="ACF3UE_002347"
     tRNA            8802..8873
                     /locus_tag="ACF3UE_002347"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8835..8837,aa:Arg,seq:ccg)
BASE COUNT         2318 a         1897 c         1648 g         3081 t
ORIGIN      
        1 ttattaaaaa aatcttacgc taagtaggat aaaataattc cttgatattt ttcgatcata
       61 tccaaataat tatcgatttc aacatactca tctacttgat gaggcaaagt aacgacacca
      121 ggcccaaaga cgacaaagtc gaaggaatgg ttagctttcg taaattcggc tgcatccgtt
      181 gttgctgccg ctccaactaa aggtaatggc tggctgaatt gttgctgaat gcaatgaatc
      241 aaaggagaat ctggatcagc tttgacaggt attttgttgt aatcgatcat caattccaaa
      301 tgatagtctg tctcttgatt caattcattg acgattgatt gcagcaatgc aatgatttta
      361 tcatttgggt attctggaat cgatcgaatg ttcccttgga gctgcgcatg gcttgggatg
      421 ctgttgactt gattcccgcc actgatcaat gtaacattat ggattgtttt tcctaggaca
      481 ggattctcga ttgtttcagc gaggtgattc atttcagcat ttgctttcgt aatgaattca
      541 tttaggtgat tgattgcatt ataaccttgg tctggcatag agctatgcgc ttcttttccg
      601 tgcgaggtga ctgtatagtt gattgatccc atgtgcgtat acatcaaact gtaattggtt
      661 ggctctccga tgatcaaggc atctaagtca tctacatagc ctgctttcgt gagctgttcc
      721 ccacctagtt cacccacttc ttctccgaca gtggctaata atttgactgt tccgttaaat
      781 ggttttcctg actctttcag ttcgatcatg gcaatcacca ttgctgccaa gccactcttc
      841 atatctgtag caccacgtcc gtacaaacgg ttcccatgga tttctgctgc aaagggtgca
      901 taggtccaag acgattcatc accagccgcc acgacatcca tatgcccaga taggcctaac
      961 acttttcctg attggccctt ttggtaacga gcaatcaaat tatctctacc atctctgtaa
     1021 gaaacaatct ctcctgttat gtcatgcttt gccaaaagct tattcaaata ggctgctact
     1081 tcaccttcgt ttccattcac tgatttaatt cggataatct cttgtaaaat cgcgattttt
     1141 tcttcttttt tcatctaatc ctctcccttg ccatttcttt ttattgtatt tgagtgtgct
     1201 cgaattttca aataggagca accaaagtaa aaatgaagaa agagagccac tttatgaaaa
     1261 atatgctgct acttccctcc tattttattt atacgagagg acttgcccat agattcctat
     1321 tctactgttc tatccttaaa agctcttata tgatgctagt tattgttagc tttccttttt
     1381 caaggatgat cttttcttgt accattcttt gtaaacatca tatacagaag ctagttgcaa
     1441 aaaaactctc tacctgctga tatttcagca agtagagagt tcgattactt aactaagtga
     1501 tcatactcga ctatctttca atagtcgatc atgtatcttc attagaaaag aattatttgt
     1561 tttttaagtt gtagaaagat ttcaaacctt tgtattctgc aacttcacca agttggtctt
     1621 cgatacgtag taattggttg tatttagcaa tacggtcagt acgtgataga gaaccagttt
     1681 tgatttggcc agcgtttgtt gcaacagcga tatcagagat tgttgaatct tctgtttcac
     1741 cagaacggtg agatacaact gctgtgtagc cagcttcttt agccatttcg atagcttcga
     1801 aagtttctgt taatgtaccg atttggttca ctttgataag gattgagtta gcaattcctt
     1861 tttcgatacc ttcagataat ttttgagtgt ttgttacgaa caagtcgtca ccaactaatt
     1921 gaactttgtc gcctaatacg tcagttaatt tcttgaatcc gtcccagtcg ttttcgtcta
     1981 atccatcttc gattgagatg attggatatt tagaaactaa ttcttcgtag aatttgatca
     2041 tttcgtcagt tgttttttcg ccttcgcctg agtcagctag tacgtaaaca cctttttctt
     2101 tgtcgtagaa ttctgaagaa gcagcatcca tagcaagaac aacgtcttta ccaggtacat
     2161 agccagcttt ttcgattgct tcgatgatta cttcaaaacc ttcttcgttt gaaccaaggt
     2221 ttggagcaaa tccaccttcg tcaccaacag aagttgctaa tccgcgagct ttcaagattg
     2281 aagctaatgc gtggaatact tcagcaccca tacgtagagc ttctttgaat gttggagcgc
     2341 caacaggcat gatcatgaat tcttggaagt cgattgagtt atcagcatgt gatccgccgt
     2401 tgatgatgtt catcattggt gttggcaata cttttgtgtt gaatccgcct aggtagtggt
     2461 ataaaggtac ttctaggtag tcagcagctg cacgtgcaac agcgatagaa acacctaaaa
     2521 tagcgttcgc acctaattta cctttgttag gagttccgtc taaagcgatc atagctttgt
     2581 cgatagccat ttggtcacga acatcgtagc caatgattgc ttcagcaatg atgttgttta
     2641 cgttgtcgac agctttagtt acacctttac cgccataacg agctttgtct ccgtcacgta
     2701 attcaactgc ttcgtattca ccagttgaag cacctgaagg aaccattccg cggccaaaag
     2761 ctccgctttc tgtgtatact tctacttcga ttgttgggtt accacgtgag tctaagatct
     2821 cgcgagcgta aacatcagta ataattgaca tgttttgtct ctcctttgag tttgtttttt
     2881 cctaagggat ttccctcata tacgatttta gttaattttg ctcattagtg caaacatttc
     2941 ttgcattttt cgcaaatttt caacaattat tttacagcgt ctaacaatga caagaatgaa
     3001 tctgcttgca agcttgcgcc accgactaaa gcaccgtcaa cattttcttt tgccatgtat
     3061 tcagcaatat tttctggttt tacagaaccg ccgtattgga tacgaactgc ttctgatact
     3121 tcttttccat aaagtttttc aactgtttga cgtacaactc cacaaatttc gtcagcgatt
     3181 tgtgcgtcag ctgatttacc agtaccgatt gcccagattg gttcataagc aataaccatg
     3241 tttgacacct gttcagctga aagatcagct aaaccagctg taatttgtcc ttcgatccat
     3301 tcagcagttt tgcctgcttc ataggtttct aaagattcgc cgcagcatag gattggtgtc
     3361 ataccatttg caaagatagc tttcgctttt ttattgatgt cttcgtctgt ttcatggaaa
     3421 tattcacgac gttctgaatg tccgatgatc acataatgaa cacctagatc agcaagagct
     3481 gctggtgaag tttcaccagt gaacgcacct gagttttccc agtagcagtt ttgtgctgag
     3541 atttttagtt ctgtaccttc agctgatgtc attaattctt gtaagaataa tgcaggagat
     3601 ccgatgactg aatcaacttt gtcatttgaa gggattttgt tttttactgc ttcagcaaat
     3661 tcttttgctt ctgatgcagt tttgttcatt ttccagttac ctgcgataat aggtttacgc
     3721 attgaggaac acactcctta atttattgaa aaatggctag ggagtcatga aaactccctt
     3781 caccttttgt tcgattactc gtcagaattg agcaaacttg gtcgtttatt tatcgttgat
     3841 tgctgctagt cctggtaatt ctttaccttc aagcaattcc aagcttgcgc cgccacctgt
     3901 tgagatgtgt gtgaatttgt cagcaaatcc taattgttct gctgctgcgg ctgagtctcc
     3961 gccaccgatg attgttgttg cgccttctaa gttagcgatt gcttcacaaa caccgattgt
     4021 acctttagca aagttactca tttcaaatac acccataggt ccgttccaaa caactgtttt
     4081 tgcaccttgt aatgtatcag caaataattt tactgatgct gggccgatgt ctaaagccat
     4141 caaaccatca ggaatgtctc cttcgattac ttgtgtttca acatcatttg aaaattctgg
     4201 tgcacagaca ttgtcgattg gcaagacaag tttgtcgcct gctttttcga ttaattcttt
     4261 tgctagttcc actttatcag cttctactag agagttaccg atcttgattc cttttgcttc
     4321 gtagaatgtg taagtcattc cgccaccgat caagatttta tctgctttag gaatcaagtt
     4381 ttcgattacg ccgattttat cagaaacttt tgcgccacca aggattgcaa tcattggtcg
     4441 ttttggttct tctactgctt caccgatgaa cttgatttct ttttccatca agaatccagc
     4501 aactgttggg ataccagttg aagcgatacc tacgttagaa gcatgtgcac ggtgagctgt
     4561 accgaaagca tcgttaacaa atacatcgcc taatgaagcc cagtatttac ctagttctgt
     4621 atcatttttg ctttcttttt taccgtcaat atcttcaaat cgtgtatttt cgaatacgac
     4681 aacgtcgccg tcattcatgt tgcggattgc ttcttctaat tgttctccgc gagtttcagg
     4741 tacgaatgtt acttctttac ctaataattc gcctagacgt tttgcaactg gagctaaaga
     4801 ttttccttct ttatcttctt ctgtttttac acgtccaagg tgagagaaaa ggattgcttt
     4861 tccgccttgt tctagaacgt agttgattgt tggcaatgct gctttgatac gagtgtcgtc
     4921 agtgatcacg ccgtctttca aaggaacgtt gaagtcaaca cggacaagaa cttttttgtc
     4981 ttttaaatcg atatctttca ctgttttctt agccatttta tttcctcctg aataaactta
     5041 ttatcaaaaa aagcggaaga agcgcgattg cttccccgct tttaaatgta catgtctata
     5101 atttacactt gtacgtttgt ctatcttata agttagcgaa gtattctaaa gtacgtacta
     5161 attgtgcagt gtatgacatt tcgttgtcgt accaagcaac agttttaact aattgtttgt
     5221 cgccaactgt cattacttta gtttgtgtag catcaaataa tgaaccgtaa gtcataccaa
     5281 cgatatctga agaaacgatt tcgtctgtgt tgtatccgta agattcgttt gaagcttctt
     5341 tcattgctgc attgatttcg tcaacagtta cttctttttc aagaactgtt actaattctg
     5401 ttaatgaacc tgttggtaca ggaacacgtt gagcagctcc gtctaattta ccgttcaatt
     5461 cgggaattac taaaccgata gctttagcag cacctgttga gttaggaacg atgtttgcag
     5521 cagcagcgcg tgcacggcgg aagtcacctt taggatgagg tccgtctaga gtcatttggt
     5581 cacctgtgta agcgtggata gttgtcatta atccttcaac aacaccaaat ttgtcgttca
     5641 atgttttagc cataggagct aaacagttag tagtacatga agcacctgag ataactgttt
     5701 ctttaccagt taatgtttcg tggtttgtgt tataaacgat tgttggaaca tcgtttccgc
     5761 caggagcaga gataacaacg cgtttagcac cagctgttaa atgtttttca gctgctgatt
     5821 tagaagtgaa gaaaccagta cattctagaa cgatatctac gcctagttcg ccccatggta
     5881 attcttctgg gttgcggtta gctaatactt taacttcttt tccgtttacg ttgaatgaac
     5941 cttcatgaac ttcaactgtt ccgttgaaac gtccttgagt tgtgtcgtat tttaacaagt
     6001 gtgccaacat tttagcatct gtcaagtcgt tgattgctac tacttcgatt ccatctacat
     6061 cttggatacg acggaatgct agacgtccaa tacgtccaaa accattaata cctactttaa
     6121 ctgtcattta agatttcctc cttatgaaaa tcaaaaaaat atttatttta aagggttacc
     6181 ccttttaaaa tctcatttgc agcagcttca tcagtgatga gccacgtttg ttttggtgca
     6241 tttttcatat aagctcgaat tgctttagct tttgattttc cgcccgcgat tgccatgatg
     6301 atcgggactt tttccaaatc ttgcaattct atgccgattc tagggacctt ataaacgact
     6361 tcaccttttt cattgaaaaa gtagccaaaa gattccgcaa cagcatttgc ttgtttcagc
     6421 atgactaatt ctttttcagt catcttacga cgtgctgcca tgtgtaatgc acgcccaata
     6481 ctatgaataa cacaattcgc ttcactaatc aagtttaaga cttcttggat agatggctca
     6541 ttgagtaaag aattgtaagt tgccagactt aattgttccg gaacataaag tgcgcggtgg
     6601 ttaccgtttg ctttagcagc cattcttgca ctgacagaat ttgcctgtac agttatcgct
     6661 tcaccaatcc cgcctcttgc agggacaaac aggttatgcc gtttcttatt ttccagatta
     6721 gacaattgtt cggctaccac agccatagta gttcctccca tcacagcgat gatattctcg
     6781 ccttctggaa gtagtcggtc taaggcttcg ctcagcgctt cgccgaatgc atcagccact
     6841 ttggtctgct cttcgctgtt tcctgaaaca acgatacagc gttggttacc aaaatattct
     6901 gccaactgtt gttcggtttg atgcgtacct aaaagctgat ccatgaagtt ttcaaggctt
     6961 tgataaactt cttcgccctt agttgtcagc gtcataccgc tttttgaggt gtcgatcaaa
     7021 ttcagatttt tcaaaaggtc tgtttctgtt cgtaagactc gttctgtgat ccccatactt
     7081 tccgataaac ttcgacgccc aatcggctgc atccaataga tatttcgtaa aattttatag
     7141 cgttcttgca acacttcgat aatatctggt gcaacagatt caatcatttt tatttcatcc
     7201 agcatagcga tctccttagt tggacacttt acgtccaatg tagacttaaa acgacccata
     7261 tacgataaaa aaagaaatta actattcgaa tttcacatca ataaagggaa atctcaacct
     7321 cacgactgta agtctaacag ttttgctctc gtttttcaac taaaaagact agaaaaagtg
     7381 aaatactttt tctagtcttt tgactgatta gttatcataa cgttttcttt ttgatgaact
     7441 cgggattcct aataaatcac gatattttgc tactgttcgt cttgagatcg ctatctcatc
     7501 ttttttcagc aattcaacca atttctggtc agacaacggc ttgtttttgt cttcttgatc
     7561 gactaattcc tgcagctttt tcttcgctgt atctgctgaa aggtcttctg tctgttctgt
     7621 actattcgta ggaattcgtg tagtgaaaaa tttttttaat tcaaatacac cgaagtctgt
     7681 ttccaaatat ttcccgttga ctgcacgact gaccgtggat tcatgcacat ctatctcagt
     7741 tgcaacttcc tttaacgtaa gaggcttgat tggacgttcc ttgtcgataa agaaagcttt
     7801 ttgccgggaa acaatgactt gagcaacccg caaaattgta tccccacgtt gtaggatcgt
     7861 tttcttcaac cattcgaatt cctgtttccg ttcttttaaa taattttcag tttctttatc
     7921 tgcttgttgt gacatttgtt tgaagtaact ctcttgaaag cgtatatttg gctgattttt
     7981 tcggtttgag ataacttgta catttttatc gtcgtccact aatacccgga catcaggaat
     8041 aatgtacaat tcgctgctac ggtcgaaaat ccggccaggg cttggactca acgtttgtaa
     8101 atagtcgaat atctgctgaa cagcatgtag atcaacagaa aaacgttgtg cgatttcttt
     8161 ccattttcgc tccaccagtt cctcaaaaca ttcttccaac acgatataag ctaattccgg
     8221 cgcataatca tctcgttctg tttgaagcat gagacattct tgcaaactac gtgcacctac
     8281 tccagctggt tctaattgct gaatcagagt caacgcatcg agcatttgga taggcgtagc
     8341 tccaatctct tttccggctt cttctaaact aatcgtcaaa aatccgttca aatcgatgta
     8401 ttctacaaga taaagaacga ttttcctcaa aaaagtatct cggtaattca aatggacttg
     8461 ttcgatcaat gaatcaaata aagacccttt tgtatcagga atctgattta ggtaatttgt
     8521 ctcttctcct tcataagaag atgaagaagc ttttatgtaa tctggctgcc attccggctc
     8581 aacaacttcc accaatggat tttccattgc ttgattctca acgaatgcca acagctcctc
     8641 actgttatat tgtaaaactt ggatggactg ttgcaactgt tgcgtcatgg ctagtttctg
     8701 tgtctgctgc tgtttttgtg aaaaattttg ctcaaatttc atttttttgt ccaatcccct
     8761 tgtaattttt tatctgttta gttacaatta tcccagtgct tgcgtcctta gtgtagtgga
     8821 tatcacgtaa gattccggtt cttgagacgg gggttcgatt ccctcaggac gcgttctact
     8881 gctattttag cataatttac gaatagttgc ttctttattt ttaagtgaaa actgtccgcc
     8941 aaag
//
LOCUS       DAXLPC010000099         8888 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.100, whole genome shotgun sequence.
ACCESSION   DAXLPC010000099 DAXLPC010000000
VERSION     DAXLPC010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.100"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(154..552)
                     /locus_tag="ACF3UE_002348"
     CDS             complement(154..552)
                     /locus_tag="ACF3UE_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFD3635716.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(549..1322)
                     /locus_tag="ACF3UE_002349"
     CDS             complement(549..1322)
                     /locus_tag="ACF3UE_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFD3635717.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1319..2002)
                     /locus_tag="ACF3UE_002350"
     CDS             complement(1319..2002)
                     /locus_tag="ACF3UE_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFD3635718.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2169..3056)
                     /locus_tag="ACF3UE_002351"
     CDS             complement(2169..3056)
                     /locus_tag="ACF3UE_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3635719.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3053..3922)
                     /locus_tag="ACF3UE_002352"
     CDS             complement(3053..3922)
                     /locus_tag="ACF3UE_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFD3635720.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4059..5345)
                     /locus_tag="ACF3UE_002353"
     CDS             complement(4059..5345)
                     /locus_tag="ACF3UE_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFD3635721.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5618..6196
                     /locus_tag="ACF3UE_002354"
     CDS             5618..6196
                     /locus_tag="ACF3UE_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFD3635722.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6196..7125
                     /locus_tag="ACF3UE_002355"
     CDS             6196..7125
                     /locus_tag="ACF3UE_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635723.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7122..8858
                     /locus_tag="ACF3UE_002356"
     CDS             7122..8858
                     /locus_tag="ACF3UE_002356"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3635724.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
BASE COUNT         2825 a         1881 c         1501 g         2681 t
ORIGIN      
        1 tagcatattt tgaaaagaaa gtctgatgct tagagtagaa tttcataaaa atttactatt
       61 tcataagtat tcacgagaaa aatacaaaca aaaaagcgga aataacgctc atccgccttc
      121 ttgtttgtgt ttatttcctc ttcaaacgct tgtctatgat tcagactttt ctctatcgtt
      181 attttcatct aaaagttctt gcattccgat aatttctcga tattgatgaa tcttagtgat
      241 accaatgact ttgtctacat caatactaaa acaaatacca ttacctggaa tatcgatgtt
      301 gatgccttga ccaatcgcat ccattacttt attcgtcaaa ctatcgggta ctaatgtcaa
      361 cacaatatct ttttctggcg aaatgtccaa acctaaaaat ttccctgaat catgtacacc
      421 agaacctctt ccatgtaaga tcgttccgcc tgctgcacct gcttcttttg aaaagtcgat
      481 aacatcttcg cccattcctc cgtcaacgat cgtcacaatc atgtgaagat tcaatgctac
      541 aagatctttc atttgctttc ccccaatttt tgcaatcttt ctttttcgat tctgtctttt
      601 tcatcttttc gtttataaat atatcctagt actaaagtgg ataatattgg tgtcaatgca
      661 atcattgcaa ccacaccaaa cccgtcaatg atcggatctc ttccttcaat ttgtgcagcg
      721 attgccacgc tcattgataa aataaatgtc gaacacatcg ggcccgttgc tactccaccg
      781 ttatcaaaag ccattgctaa aaagatcttg tccacttttc gtcctaaaat aaatgctagc
      841 ccgtatcctg ggatcaagaa ataataaaga gagaatccga cgagcaaacg ccacatagac
      901 aatcctactg ctgcgccgat cccaattgaa attaccatca gcatgatttt cgatcggatt
      961 ctcccctcgc tcaattcttc aacctgtttg atcattacat gaatcgccgg ctcagcaaac
     1021 cctactaaga accccattaa aaagccaagg ggaaccagta tataattgta aggcaatccc
     1081 gcaatagcac tgcctaaatg ctgtcctacc ggtacataag ccatattgac tccgtgcagg
     1141 aaaaggatca acccaatagt cgttatcaag aaacctttca taatgtcaaa gaaacgcttt
     1201 ttgcgcatac gaaaactaat gatattcatt aaaacaaata ggattacgat aggtgccact
     1261 gccaaaatga cttccatggt aacgatttcg attccatcta tcacttgctg ccagaaactc
     1321 attggaagat cacccccaaa atcatcacgg caagaatcgg ccctaacgaa gcaataccga
     1381 ccattccaaa actgtcattt tcatttttct tttgtttgat catactagtc atccctccgg
     1441 caagggccaa gataaatgga acagttactg gaccagtagt cactcccccc gaatcaaaag
     1501 caatcggcat aaattcggaa ctggtgaaaa atgaggcgat caaaacgcct atgtagccta
     1561 tagccatcaa ttgataatag gatagcttga atacgacccg aagcagcgca aaggctagaa
     1621 atactccagt gccgacgctg acgatcccaa tcagcaacac tctgccaatc tctccgtcag
     1681 atatatcata tacttgttgt cccaaaactt gcacggaagg ttcagcaatc gtgatcacga
     1741 tcccgatagc aaatcccaaa ctgaccaaaa cggtcaaact tttctttttg atcatatatt
     1801 tccctactag atctccgact tccatcatag aataatctgc tccaaacaaa aagagcgtca
     1861 ttccgatcat catgattgcc gcaccaacca gaaatgaagc gaggtcttct ccttctaacg
     1921 gtgcaaaaac aaacgttaaa atgacaatca ggacagtcat cggcaatata gcagcaatca
     1981 cttctttaaa attttttagc atgtatcctc ctcctttact ctttaagttt accttaaaat
     2041 gaaagagttt tcgagcacaa acttaaaacg ttatcattta atttttctca acataaaata
     2101 acacacgtcc caaaagtatc tttttacttg gaaaaatgac tttgaaggaa cgcgcttatt
     2161 gtgttttttt attttacaga gccgatcatt ccttgaacga attgcttttg caaaacaaaa
     2221 aatacgatgg cagttggtaa agtagcgatg actaatccag ccatgatcat tccatagtct
     2281 ggtgtatagg aagcacccat agcagataaa acaagcggaa ccgtccgttt atcaggagat
     2341 tgcaaagcta ctaagggcca taaataattg ttccagctac tcatgaatgt gatgattgca
     2401 gccgcggcat aggtattttt agccgtcggc atatacactc taaaaaaaat acttagttct
     2461 tttagaccgt ctaatcgagc ggcttctact agatcttttg gaaaagattt aacattttgt
     2521 cgaaagaaga agatcaaaaa agcagtgcta acagatggca ggatgacaac caagaaactg
     2581 ttgattccca aaaccgttcc gttcaattgt gaaaacattc gatataaagg gatcatcaat
     2641 gccgcaaaag gaaccatcat cgatagcagt agaatattga aaattaggtc ttttcgttta
     2701 ctttgataaa tctcaaatcc atatcctgcc attgacgaaa tcagcaatgc aaacacagtg
     2761 gtcaccaaag cgatcatcgc tgaattccaa agggaacgag taaaattcag ctcattggaa
     2821 aacaaatttt gaaaattgat gatcaagtta ctgccaatct ttatttttcc cgatgtgata
     2881 tccacgggtg tattcgtcat tcccaaaacc atccagacaa aagggaaaat ggaaataaat
     2941 gataggatgc ttaatgctgt atactttaat actgacccaa ttgtcgaacg aagttctaat
     3001 gcttgttttt tgacgttggg gcgttcgatt gtttcttttt ctaccatatt tttcatcgac
     3061 tttctcctcc tactttcgtt tggattatcg acaatatcac aataaaggaa acaataacaa
     3121 aggaaactgc tgccgcatat ccaaaattag gcgtgaattt ataactcaaa ttatagatgt
     3181 attgagatag ggtggtcgtt gcatttgctg gtcccccgcc agtaatattt tgtacttcat
     3241 caaaaagctg caatgtcccg atcgtcgaag taatggaagt aaacaaaatg attggtttta
     3301 aatttgggat cgtcactttg ataaactgct gccatttaga agcaccgtca atagatgctg
     3361 cttcataaat ctccgaatca atattttgca tgcctgaaag gaaaaaaatc atattgtatc
     3421 cagtccaacg ccaagtgatc gaaagaatga tcagaactct cgcccaaatt ggatgagtca
     3481 accagccaat cggtgtgtca atcataccaa tgcccaacaa caagttgttt acaaggccag
     3541 attgagaaaa tagacttttc atgatcagag aataactgac catcgaagtg atacatggaa
     3601 gaaagatagc ggttcgaaac aaccctttat atttcaactt tttatcattt aaaaggttgg
     3661 aaataaaaag tgctagaaac aacatgatcg gtacttgtac aagtaaatac aggaatgtat
     3721 taaaaaaagc ttttttaaaa gttgcatctg tcaacatccg ctgataatta cctaacccgt
     3781 taaatgtcat attgacaggg ggaccacttt gaaaagacgt gatcaaagcc aaaaccatcg
     3841 gaataaaaac catgattgat atcaaaatga ctggcaagat taaaaaagca tgcccgtttt
     3901 tgaataaatc tttctgcttc attcttttcc ctccaattct atcattgatt atctacatga
     3961 aaagacaaga aagacaatat ctgtaaggca gacgtgatct tttttgtctt ttcgtttgtc
     4021 tgatgaaaaa gcgaagaaat tcactttttt accaccgatc aattagccaa ttgtgcttct
     4081 acttgttttt gtgtatctgc tagtaccttg tctgtctctt ctccattgat gattcgatga
     4141 agagcttcag ctacgactgc ttcaattgca taggtctcat gtccgtaatt cacttctggt
     4201 atttcagatg tccatgttga aaaatcgtca aagatctttt gaccactgta aaattcagaa
     4261 gcttcttgat aagcttcttg ttcattcgcg ctaagcatcg tagatactag tccgatttct
     4321 ttcgcaagag tgcccatcag ttcttcattc gaagcaaacg ttgcttctag gaaatctttc
     4381 gctgaatctt ctccagctac tcctttgatc acataccagc cagcgccgcc aaggttagaa
     4441 gcttgcgctt tttgcagatt ttctggaagt gcaggtattg gtgcaatctt ccattttcca
     4501 gattggtttt ctgctccttg gatcgttgaa gaataccaag cgccagttgg gctagaagct
     4561 actgctcctg attgtatcgc agttactcca gcattccagt cagaggtttg ttcgactaga
     4621 tcttctttca aaagagtggc aaacaattca agaccatact ttaaagatgc attgtcttgg
     4681 atcgtgactg tctccccatc ttcagatgta taccattctc ctgcctgttg cataatcatc
     4741 cttactcgac caaggtcaga aggattgact tcagcgattt tctttcccgt cttttctttg
     4801 acatctcgcg ctacttgaat atactcgtcc cacttcagat tctccatatc ctcttctgta
     4861 taacctgctt ctgccatcag atccgtacga tagaagtttg ctgttacgcc cgaatcgaaa
     4921 ggaacaccgt atattttatc tcctactttg tttaccgcaa atttatacgg tgcaaaatga
     4981 tcttccttta caatagcaga caaattagcg aatgcatctg gataagaagt caaatagcct
     5041 tgtatcctat aatcttcaat caagacgata ttgggcaatc cttctgtatt cccgctcgct
     5101 aaagcggtgt tcagtttctg aacgatatca tcctgagaca tcgtaacaac ttctatctct
     5161 gtttcttcgt tctcataaac tttttttgct tcattcactg ctttgatatt gaatgtctca
     5221 tcccacgccc agacagtgac tttttcttct ttgtctgctg tactactagc acttccgcat
     5281 cctgttaaga aacctgatgc tgccgctaaa caaacgactc cagcaattaa ctttctgatg
     5341 ttcattttta tccgctcctt ttccatccat tagttgttta cgtttgctac attcatcata
     5401 ccaaaatttg aaaacggttt ctttattatt cagatacttc aaaaatttct cctaaaataa
     5461 taaaaaaata caaatcaact atgacaaaag gaataatctt agcatctaga ccaaagatcg
     5521 aaatggtgag gtttctttaa aataaaaata tccttgcatt ttctcctaga aataagtatt
     5581 tttaaattac aagactattc ttaaggcggg taaaaaaatg ccaatacgcg taattcttat
     5641 cgatgatgaa cagacgattt tagatggaat gaaacagttg atcaattggt ctgagcacgg
     5701 gtttcaatta atagggactt tttccagtcc gctgaaagcg cttgattttt ctttggtaca
     5761 tgcaatcgat atcgtggtca cagatgtaat gatgcctgaa ttaaatggaa tcgaattatc
     5821 gcggctatta aaacagcaac aacctgaaac acagatcctt atcctctcta gctatgatga
     5881 atttgatatg gttaaagatt cttttaaaga aggcgtcgct gattatcttt taaagcctcg
     5941 attgagtcct gatttttttc taaattcctt aactgccgtt tcacaaaaaa tcaaaaaaaa
     6001 gcccaacaaa agcccaatca ccaatcgtta tgagcagatc tgcgagaatc tttcacagca
     6061 gattgctgga caaactcgtc cattgcttga ccctcttctt tttgaacaca ccttgttttt
     6121 ctgttatata ccgaaaaacg gccattcagt tcaaaacaag gctctaaaca aaaacagtcg
     6181 atcacccatt cattgatgga tagcgacgat tcgtttacta tttatcctgt ttctaccttt
     6241 tcggaagaat ccggctatgt aatcaatact gattccaaag atacacttag gaagtttgtt
     6301 caaaagtttc gtcaagaagt ttttccaggt gatttttttg ttgtttctga ttcttttgca
     6361 atccaagata tcaatgaaat attccaagag atcagaaatt gcaccaaagg acaacgtttc
     6421 tatcataagg gaaagaacct tgcttatcag catgaacttc ttccgttatt aaccaaccac
     6481 gagcagcaag caagtagtta tttaacaaaa atcgttcata aagactacgc tttagctgtc
     6541 aaagaacttg agaatttctt cacgacgata ttggaacagc ctattgatcc agcttatttg
     6601 aaacatgagg caatcaatcg tttctatgca ttactcaacg ctttggctga cgagcatgtt
     6661 gggaatgaag aactttcttt gctcaagatc gcccttcctt ctttattagc cgatgctgag
     6721 tatttcgaag atttttctat tcttgtcaaa gaaacacttg agaaactcac ccacttttct
     6781 gcaaatgcaa aaaaagacaa tttcgatatc ttgactttga tctacgagtt cgtccaggaa
     6841 aattatgaga aagaaatcaa tttacaactt ttatccgaaa aatatcattt ttcatatagc
     6901 tatctctcag ccatctttac tgaaaaattt ggtatcaact tttcaaaata tctaaaaaaa
     6961 gtccgtatca gtaaagccaa gctctttttg acggaaacac ggcttacttt gacggaaatc
     7021 tgtgagaaag tcggctatac cgaactgggt tatttctcca gagtttttaa agaagagaca
     7081 ggaatgacac cttctcaata ccgtaaagga acttttgtaa aatgagaaaa aaaatcaaag
     7141 agcatgaact ctttgccaaa cttctgttca ttttgttcat cggtcttttt ctgcaagcca
     7201 tcgtcatttc tttgtttatt tatcatcgat caagggatgc ctatatccag ctgttcaatc
     7261 aatcgaatga tgtggtacta aaaaagattc aatctgaatt tgaaagtttg aatgatacaa
     7321 tcgagaatac attagccgct tttgattcta atccagctgt caaaagctat ttttccaatg
     7381 atccagccca acatatggaa cagcttcagc aactaagaac aatccaaaaa atgaatgact
     7441 ctctttcaaa aatccatcca atgatcgatt acgatgtatt gatctttgga gaaaatggaa
     7501 gaacttttgt cggaaacgac atgctcactg ccgtatctgc cgattctttt tttcaatctg
     7561 cgattgctca gagagtgaat gaacgtgctg ctgatacaca aatgcttttt gcacaccacg
     7621 gattgactct tcgcgataag aaagcaccca gcgtcttctt tgtcaaaaaa ctgaaaaata
     7681 cattgaatca cgtttacgga tatgctgttt tatcgatctc atccaagcaa ctagcgaatc
     7741 tttttcaatc tgtagtaaat cctgagatat cgaagatctc cttcatgaac gaagaacaga
     7801 cgatcatcgc atcaaatgaa gaaaatacaa ttgggagccg atcaatgatt ttcaaaaaac
     7861 taacagtagg tgaaacaacg atttcaaatg gacagcagtt gacccgtctt cctctgtacc
     7921 gccaggattg tacattactc agtcaagtcg atcttcattc tttatctaac caaatgggcg
     7981 tgatttttcc gattattttg tataatatcg tgacacttgc ttttgctggc tcattggtat
     8041 ttatgtattt ggatcgacac acaaaatcga tctaccgctt gattgattcg ctaaaacggc
     8101 tagaggaaga tggcttaaaa gctactgttc ctgtacaagg aagccatgaa gtccaattgc
     8161 tagggaatac gatcaatcaa ttgctaagta atgctcagca tcattatgaa cagacgatcc
     8221 aagacgaaaa gaagaaacgt tcgcttgaaa tccaaactat gcaagcacag atacagcccc
     8281 attttattta taatacgctg actagcttga aatttttgat ttggcagaaa aaaacagatg
     8341 aagcagttca aggaatcgac agtttcatta ctttactaag aagtacgatt gggaaaaaag
     8401 aagaagtgat tccagtcaag gaagaaatca aaagcgtaca aagttacatc gatcttttga
     8461 gtatgcgata tggcgaaaga atctcggcta aaataatgat tcctgatgaa ctgcagtcat
     8521 tatctatgcc gaatatgatc cttcaaccaa ttatcgaaaa cgcctatctt catgcttttc
     8581 acaataaaac gcaaggattc atcacggtgt acggcaaaac aaaaaatcag cttcttttat
     8641 tcgaagtgat tgataacggc gatggcttcg atactgaaaa taccaaacaa aaaaatgatc
     8701 atttttcagg aatcggcatc agccatgtag atgagcggat acgcctaatg tatggcgatg
     8761 catatggctt aacgatccaa tcagtgattg ggacaggaac gactgtaacg atttgtctac
     8821 cgcttcttcc taaaaatcaa tcagaatatc aaaaataaag aatagccaag cgctgatttt
     8881 tttatttt
//
LOCUS       DAXLPC010000100         8844 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.101, whole genome shotgun sequence.
ACCESSION   DAXLPC010000100 DAXLPC010000000
VERSION     DAXLPC010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8844
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.101"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(18..287)
                     /gene="rpsN"
                     /locus_tag="ACF3UE_002357"
     CDS             complement(18..287)
                     /gene="rpsN"
                     /locus_tag="ACF3UE_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFD3635725.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(810..2576)
                     /locus_tag="ACF3UE_002358"
     CDS             complement(810..2576)
                     /locus_tag="ACF3UE_002358"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635726.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(2536..4290)
                     /locus_tag="ACF3UE_002359"
     CDS             complement(2536..4290)
                     /locus_tag="ACF3UE_002359"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635727.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(4400..4969)
                     /locus_tag="ACF3UE_002360"
     CDS             complement(4400..4969)
                     /locus_tag="ACF3UE_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFD3635728.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(4987..6402)
                     /locus_tag="ACF3UE_002361"
     CDS             complement(4987..6402)
                     /locus_tag="ACF3UE_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFD3635729.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(6413..7081)
                     /locus_tag="ACF3UE_002362"
     CDS             complement(6413..7081)
                     /locus_tag="ACF3UE_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFD3635730.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(7211..7795)
                     /locus_tag="ACF3UE_002363"
     CDS             complement(7211..7795)
                     /locus_tag="ACF3UE_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3635731.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(8126..8359)
                     /locus_tag="ACF3UE_002364"
     CDS             complement(8126..8359)
                     /locus_tag="ACF3UE_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFD3635732.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(8374..>8844)
                     /locus_tag="ACF3UE_002365"
     CDS             complement(8374..>8844)
                     /locus_tag="ACF3UE_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002907381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFD3635733.1"
                     /translation="IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPND
                     KKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVES
                     SVDDRPMKTVSKDTNIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
BASE COUNT         2948 a         1614 c         1174 g         3108 t
ORIGIN      
        1 catgatattt cctcctttta ccaacttgct ttttttactc caggaatcaa cccttgatgg
       61 gcaagttctc taaacttaat acgggacata ccgaactttc gcatataccc tcttggacga
      121 ccatccgtct gatcacgaag cctcagacga ttcggatttg aatctcttgg caatttagcg
      181 agagcggtgc gatctcctgc ggcttttaat tcctgacgtt tatctgcata cttttcaatc
      241 atcgccattt gtttctttgc tttagcaatt ttcgactttt ttgccatata cctttatact
      301 ccttttattt tgatttagac acctcaaatc gtaatcgtta cgttttgaca ctgatacttt
      361 accaacaaga gttgctcttg tcaacaataa ataacatgaa ataaaactca tatgaataga
      421 taactatttg aaaacgaatt tatcggtaca tagagataat caaatcattt aaaagaatat
      481 gcagtttagg ctctgaaaaa taagaattca cttttattag tccaatcaaa cacaaatacc
      541 gttttaagta gcttttcctc tacttaaaac ggcaatatga aagaaactat aactttttat
      601 tcaatctttt atgtttaact ggtttatcgc caatttttta aaactttgat tattccttat
      661 attataagaa tagacattaa gtgaactaat tcaatcatac tgattctttc gtgtattcaa
      721 aattagatgc tgtttaataa aattattctt tttgaaaaag aattataact atatcccaaa
      781 aattgtaggt taatttaaag cctatttcat catcgtgatt gagcttcttt ttcatagacg
      841 aatttctcag atagtttagt tttctttatg agatttttgt atatttctga ccttcgatac
      901 aactcattat gagtaccttg atcaactagt tttccttgat ccatcactac aattttattt
      961 accttttcaa tagacttcaa gcgatgcgat ataattagta ctgtcttatc ttgtattaaa
     1021 cgatttaaac tttcctgaat acgtttttca ttttccgcat ctaaactggc agtaatttca
     1081 tctaaaatta aaattggcgc atttttcaaa aaagcccgtg ctatggatag gcgttgtcgc
     1141 tctcctccag aaagtgaact tccgttttct ccgaccaatg tatgataacc gtcaggtagt
     1201 ttttcaataa agtcttcgca gttagctaaa cgagctgctt ttttcacttc ctcatctgac
     1261 gcttgactat ttccaatacg tatattttcc aaaatacttg tattaaacaa agttacctct
     1321 tgaaaaacaa tagcgatttt gctaaacaaa gaagctggag atacacgttt aatatcatac
     1381 ccatcaatta aaatacagcc ttcatcataa tcatacagtc tagacactaa tttcaagata
     1441 ctagttttcc cggaaccact agcacctact aacgcagtca cttctccttg tttagccgta
     1501 aaagagatat gatctaaaat tggggtattg ttatcatatg agaaagagac atctcgcaac
     1561 tcaatgtcaa aagatttcag aggactatct gatccctctt ggatactggt ttccttcata
     1621 gctctaattc gctgtatttt aggagctaaa taaaatattt caagcactgc ttctttcata
     1681 gaatcgaagg aatcctttat ttttattgcg gctagtaagt aaccaacgac gtagagtata
     1741 gtcacttcac ccgttaacag taagtgaaca cctactagaa tgactactgc taaactaaca
     1801 tatgagaaaa tagaggataa ggccatgact gaaaaagtac ttaattctac ctttaaatga
     1861 atcctttcac tctcttccat ttttttgaaa agtctgtctt gaactttttt agatagatta
     1921 aagctattaa tctcttgctg caattctata gtttcttgaa attcttccga gttttctctc
     1981 aaagtatcgt aatatttagt attggctttc gtttgggatt tctttgataa caagattaag
     2041 acaaaactaa ataacgttgg caaaataaca gctaatccca ttttgacatt accaaccaaa
     2101 agcatcactg aaataaaagg gaaaaacaga gccataccgc cggctttagg tattgcatga
     2161 ctcatcgcat gctcaatacc ttcaacgtca gacatgatag tttgagataa atctgataaa
     2221 ttatgttttg aaaaatagga taatggtaaa tttgacaaat cgtctgcaat ttgcactctt
     2281 aaatgcgcac tttctttata agtactatta tataagtttt catactccct atctaacaac
     2341 caatacatga aaagcaaagt aacaaacgat acggcaaaat aaagccaacg gggctttgta
     2401 ttttctaaaa ctaattcgtc tatcagcatc attataatga atgctggtac catattaatg
     2461 cagtatacaa aaaaactaga aatagaagct ttagttaaag cttctgcgcc ctgatcactt
     2521 aaagcaaatt tgtttttata aaaacttttc attgtcaagc ctccaatcat ttgcattctc
     2581 ataattagtg accaattgtt tatacacttg atgtttagcc attaattcat tatgatttcc
     2641 acgttctact attttccctt ctgacaagac aagaatttca tctacagatt taatgctgga
     2701 taatcgatga gctatcataa taactgtttt ttcttttatc agatgttgaa aagccttttg
     2761 tagttcatac tcattatctg gatcaataga tgcactggct tcatccataa taacaatctt
     2821 tgcatctttt aaaattgctc tggcaatagc tatacgttgt ttttctcctc ctgacagata
     2881 aactccttta ctaccaatta aggtatgctc tctttcggga aatttttcta aaatcgattc
     2941 gcaaccggct aatcttagcg cgtcaaatac tttacttgct ggcgcttgag gatttgctat
     3001 agaaacgtta tcgtaaatac tctgattgaa tagtttcgta tcttgaaaga caaaagcaat
     3061 tgtgttaata attgtgtctt ttgaatagtg atttaaaggc ttaccaccaa ttttaatctg
     3121 tcccttatcc acattgtaga aacctgaaat tagtttagct atcgtactct ttccgcttcc
     3181 tgattttcct actaatgcat aaattctttt ttgttctaaa actaagttga aattttctaa
     3241 aacacactct tctttgtatg aaaagctgac attttcaaat gcaatgtcac aatttttaat
     3301 ctgtgtctcg ttcccatatt ttagttggtc ttgcttcatt tctaaataaa gggagtctag
     3361 tgtttcgact gcatatcttg cttcaaacaa gtgcatactt acatacatta ttctcatgaa
     3421 agaaacaaaa ataattccac ttaaaaaaaa caacatcaac aagtcaacag ctaatatctt
     3481 gggagtggta agagaagtta taaaaaaggt tataggaact atcaaaatgc aaactatgcc
     3541 aaaaaatagc cattgaaaaa gaacaaaagg tgttttccca ctcaaagaat acttatatgc
     3601 aaacttagca taatcgttaa ttgctttatt caaggcttta aatgatgtta ctttagcacc
     3661 aaatatcttt ataacttgaa ttccgcggat atattctacc gtttcagagc ttaacacatc
     3721 taacgattct tgatattttt gaataaaatt tgtattctct gtcattttct ttaacaagaa
     3781 tacaccaatt actaacatgg cgattagaac caatccaatt ttaaagttaa tgaaaaagcc
     3841 taaggcaact gataaaacag gtgttactat ggcttgagca ctatctggaa tcaagtgagc
     3901 aattgccata tgtgttttag ccgcgttgtc atcaattgtc tttcgaatat atcccgaaga
     3961 atttaaatca aaaaaacgaa aacttgcttc tgttaaaccg ctaattccct tttttctcaa
     4021 attagtctct aagcgaaacc caaggatatg agaaaataag ccagaaaaaa tataaaataa
     4081 agctcctaaa gttaaccaag caacagtttg aaccgcataa ctcttagcta aatattcatc
     4141 tcctacaata attagagact gaagaaattt gtaaatactg taatatccat agactgttaa
     4201 tacgacagaa aaatcagaaa ataaagtggc taaccatccg tagtatttca ttttagggac
     4261 ataactaaat aattttttgt atactttcat tttttcctcc cccgcattca atttcttctc
     4321 ttattcgttt acaactgtta atgctttccg taatagcgta aattagagat gtacaaacag
     4381 ataaaaggta aactacgttc tattttttgt atttttttaa gacttttctt ccaatcaata
     4441 caccaatcat agataaactt gctacaacta acactgaaat gattccccat atacctaccg
     4501 catagtggat cattgcatcc attgttgcag cagattgtcc tttatctatc caatcttgac
     4561 gaaaacgatc tgtaaagaac catataggaa tccactgtcc ggcagcactg cctaattgca
     4621 ttagagccca agacgcaact tgaggaattg ctcgatcata tccaaataca gatagaataa
     4681 tatcagctaa gatcgccata ctaatcgaac tgataaacca aggtaagtac gccccgccca
     4741 ttaacgtaaa aaataacaat aaaacaattg tgtaaatagt aaaaattcct tttctagggt
     4801 agttatagct aatataaaca aatatgattc cagataataa tccaaaaatc ccgggggata
     4861 tgctgtgacc aaacgcccca ccaatactac taaccattat tgaaaaaaag taaattacta
     4921 gggaaataac tgtagctaaa ccaataaaaa tataatcttt tgttttcata tatattctcc
     4981 tcaattctat ttcgttatgt cattaaaaat ctgttctatc aaagttgaat cttctactct
     5041 aagttttata tcttttttta ttccaccatt ttttaaataa ataattctat tgcatgtttt
     5101 ataaagaaat tccggatcat gagtagctat aactactgca cccttttctt ttaagtcttt
     5161 aataaggtca gcaatccttt ccatattaat ataatccaac ccacttgtag gttcatcaaa
     5221 tagaaataaa ttagtttttg acaatgaagc tatagaaacc aataatcttt gtttttctcc
     5281 accggataaa tcaaacggta attgatcttt cattttataa agttccattt tttttaaaat
     5341 tttttcttgc tgatctttac taactatttc attccccagg gctaactcgc tcctcactga
     5401 ttctgtgaaa aattggtaat ccatttcttg cattactaaa aacggcgatg acaaattttt
     5461 tttattttcg attatctttc ctttggtagg gcgaataatc ttcatgagta ttcttagtaa
     5521 ggttgttttc cccacaccgt ttttccctac caaaccaata acatctccaa ctttgacatc
     5581 aaaatttatg tcttttagaa tattttcata agtaatttct tcaactttta atacatctgc
     5641 acttaccttt tcgatatagg gaacttcaat cgaactatta aaaatgtcaa atttccttaa
     5701 tgcgttattg ttttcagttt ttaacaactg aatagttgta gtttttacag ttctattttt
     5761 aacaaataga acttgatcaa ttaattcttt caaatagtaa aaacgatgtt cagctataac
     5821 aatagtaaat cctttatttt ttaaatcaca aagtaagtca gcaagtttct tagtcgcttt
     5881 gaagtccaaa tttgaagacg gttcatccaa tataattaat ttagagttta gcgataaact
     5941 acatccaata gaaattttct gccgttcacc acttgatagc gaaaaaatgt ttttatctaa
     6001 tatatttgaa agatctaata attcagctaa ttcattgatt cttttatcca tatgctcttt
     6061 tgtaaatcca aagttttcca tcgaaaatac taactcactc gttgtatttg ttgtaaagaa
     6121 ttgtcctcta ggatcttgac ttacgtagcc aatatttttt gatatacttt cttgtgttaa
     6181 ggattgtagc gagttatttt caaataaaat ttccccaacc aattttccgt cataaagtct
     6241 tggaataagt ccattcatta actttaatag tgtggatttc ccactcccag aagaaccagt
     6301 aatcaatgta agactgcctt tttttattga aaaattaagg tcaacaagcg cttgttcctt
     6361 aacatcctta tatgaaaaag aaacattgtt aaattcaaac aattctttca cctcaaatca
     6421 aaatacttaa gaaaaaaata gtaacggaaa acaggatgat atagtctaat aagctcatgt
     6481 ttgttttata gtaagaactt cttttcacag gagattctat cccctttgtt attgcattag
     6541 cggtcatttc ttcagcaatc atagttgcac gtataagaac gggaactaac agaaattcca
     6601 aatattgcag aggctgaaaa aaagacaagc gaatgtttct catttttaaa gattctttaa
     6661 tcattcttat ttcagaacga taagtcggaa agaatctgat cactactgta atacttaaca
     6721 ttattttttt cggtaaatgt attttttcta aagaggataa taattcattg ctagtataga
     6781 cactaaccaa caaccatgag atcattacga ccggcaacat tcgaaataca atatataagg
     6841 atgtcgcaaa aaatatagta aaaaactcta tcttgatagc atcaataatt ttcattacta
     6901 aaaacagaac tgaataaatc aagatgaaat aaatacatgt ctttatttta cgaaacatca
     6961 atactaaaac tgtagcaata atgaaacacc ccacttgaaa tatatttccc tttcctaaaa
     7021 aaataatgac cggaaaaaaa atatttaaag taatcaaggt taacggattg atttttgaca
     7081 ctctttcacc tccaaaaaat aagatcgcac tgttatctta agctgataaa aatgcaccgt
     7141 tattcagata acagtgcgat cttatcaaaa agcataactg agaacaattc tcaatgcaag
     7201 ctttttttaa ttaactcagt aattcaatcc acccaggaac agaaaattga tacaatcttc
     7261 tggttaatag catagtcttt tcttttgaat agctatgctt caatatatca tagaatgtag
     7321 cgtagaatga gtaaatgtag aagtggattt cttcttcatt aaagactaaa ttttgattga
     7381 tcattccgat agtctttaac ttatctagac aacagactgt ctttttcgtc acaaatgatg
     7441 taattttttc aacaatatct tgatatttgg ttccagctga ttggaataaa atcaaatcga
     7501 atatacgttt attctcaaaa atataattaa taaatggatc taattcattg aagttctctc
     7561 tccaactttt ctctatatct atattttcta agtttaagag gtatttggta aactcttcat
     7621 tatacatatt aataagcgca ttaatatgcg gctgaataat ttcttcaaat aacgcttcct
     7681 tagaagtaaa atgtttataa aaagcacccg tagttacgcc tgcggtcagg cacagttgcc
     7741 ttatcttagt ttgctgaaat ccttcttttt caaaatggct tagtccactt tctattaact
     7801 tttggtgagt tataatataa tctctggttt ctatgggtac ttcctcctaa taagatgaat
     7861 taactttatt atcttacaca ggacttgaag tttcaatcgt taacgtttat tactgaactc
     7921 attccttaga gctaaactaa tgagaaagag cagaataact gatacaaaaa gcaatcctac
     7981 aagaattaat agactcatct aaatcattca ccttttctaa aataatccga gaaagattta
     8041 aaaaaattat atccagctat taggataagt cctatcataa tcactccaat agccattttc
     8101 ttatcctccc taaaaataaa gtcttttact taaaaccttt tttgtaatcg tcaataaatt
     8161 ttttcccttt atcagttaat tgaaatccta tatctaaata gtcctcatat ctaagtttag
     8221 ccagcatctc acttacagat gctggactaa cacttagaac ttttgctaaa tcattatttt
     8281 ttaatttctt ttttcttttt gataattcct gaattgctag taaataaatt agtatagtag
     8341 tcgttttaat ttgtaccata cctaccctcc aaattatttc gaaaggcctt cagcaatttt
     8401 atccaggttc catttcatca tcgcatagta actatcacca tcttgtcctt tttctgcaat
     8461 tgaatcagta aaaatcgttg aatagatagg aatattggta tcttttgata ctgttttcat
     8521 tggtctatca tccacactgc tttctacgaa taaggaggga acttttgttg tgcgtaattt
     8581 ttcaactaag tgttttattt gatctggtgt tccttcttct tcagtgttga tttcccaaat
     8641 gtaagcagaa ggcacattat acgctttcga gaaatattta aagcatcctt cacttgtaac
     8701 aatcattttt ttatcattcg gaattgaagc aaatttagat ttagcttctt tgtctagaga
     8761 atccaatttt tcaatatact tatctagatt ttctttatag aattttttat tatcaggatc
     8821 tttttccgct aactgttttt caat
//
LOCUS       DAXLPC010000101         8586 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.102, whole genome shotgun sequence.
ACCESSION   DAXLPC010000101 DAXLPC010000000
VERSION     DAXLPC010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.102"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(45..1511)
                     /locus_tag="ACF3UE_002366"
     CDS             complement(45..1511)
                     /locus_tag="ACF3UE_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFD3635734.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1898..2494
                     /locus_tag="ACF3UE_002367"
     CDS             1898..2494
                     /locus_tag="ACF3UE_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFD3635735.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2552..3034)
                     /locus_tag="ACF3UE_002368"
     CDS             complement(2552..3034)
                     /locus_tag="ACF3UE_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635736.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3140..3337)
                     /locus_tag="ACF3UE_002369"
     CDS             complement(3140..3337)
                     /locus_tag="ACF3UE_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635737.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3632..4390
                     /locus_tag="ACF3UE_002370"
     CDS             3632..4390
                     /locus_tag="ACF3UE_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFD3635738.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4450..4878
                     /locus_tag="ACF3UE_002371"
     CDS             4450..4878
                     /locus_tag="ACF3UE_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635739.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4924..4996
                     /locus_tag="ACF3UE_002372"
     tRNA            4924..4996
                     /locus_tag="ACF3UE_002372"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4957..4959,aa:Gln,seq:ctg)
     gene            complement(5146..5517)
                     /locus_tag="ACF3UE_002373"
     CDS             complement(5146..5517)
                     /locus_tag="ACF3UE_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFD3635740.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5732..5917
                     /locus_tag="ACF3UE_002374"
     CDS             5732..5917
                     /locus_tag="ACF3UE_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635741.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6000..6188)
                     /locus_tag="ACF3UE_002375"
     CDS             complement(6000..6188)
                     /locus_tag="ACF3UE_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635742.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6212..6475)
                     /locus_tag="ACF3UE_002376"
     CDS             complement(6212..6475)
                     /locus_tag="ACF3UE_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635743.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6633..6890
                     /locus_tag="ACF3UE_002377"
     CDS             6633..6890
                     /locus_tag="ACF3UE_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFD3635744.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6961..7152)
                     /locus_tag="ACF3UE_002378"
     CDS             complement(6961..7152)
                     /locus_tag="ACF3UE_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635745.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7293..7613)
                     /locus_tag="ACF3UE_002379"
     CDS             complement(7293..7613)
                     /locus_tag="ACF3UE_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635746.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7636..8070)
                     /locus_tag="ACF3UE_002380"
     CDS             complement(7636..8070)
                     /locus_tag="ACF3UE_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFD3635747.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8405..>8586
                     /locus_tag="ACF3UE_002381"
     CDS             8405..>8586
                     /locus_tag="ACF3UE_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3635748.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT         2719 a         1694 c         1361 g         2812 t
ORIGIN      
        1 aggaactgct gcaaataagc aattcctgtt tttatgttca ttgattaatg aatagagccc
       61 attagttttt tgattggttc tttcacagta aatagcaaga taccaccgac gattgctact
      121 gcaccgataa taccgaagta agcagattct gttcccggtg tgtagaagcg tgcaatttgt
      181 gcattgattg cttgtgaaga agcatcagct aagaaccaaa tagcgattgt ttgtgattca
      241 aatgctcgtg gtgctaattt tgttgtcaca gacaaaccaa ctggtgaaag acacaattca
      301 gcaataacca cgatgaagaa acttcccaac aaccacaatg gacttacttt tccacttgta
      361 ccataaagca tacccggcaa catcaatagc aagtacgata atcctgcaaa taaaagtcca
      421 agagagaatt tcactactgt agatggttga cgttcaccaa gtttcgtcca catcgttacg
      481 aatactggtg tcagaataaa gatgaaaatt ggattcaatg attgatacca gcttgcttgg
      541 atcgttacac caaatagcgt agattgtgta cgttcactag caaataaagc taagatagat
      601 gaaccttgtt cttgtaatga ccagaaaatg attgctgcaa ggaataatgg gatataagcc
      661 catactcttg gtttttcttc agcagttaca tcttttgaag tcagcatttt gataaagtaa
      721 tacaacggta agataatccc caatacactg attgtattga caaaaaagtc aattgtcaga
      781 tgaccagtta gttgtgcccc gccgaatact gcagcgataa caacaagtgc gatgatcaag
      841 ttacggatga atcctttacg ttcttcagtt gtcaaaggat tcggcggtgt tgtacccact
      901 ccgtctaatg tcttgcgtcc ttggatgatg tattgtaata atccaaagaa catcccaata
      961 gcagctaaag agaaccctaa atgatagtta tattcttgac cgattgtacc aacgattagt
     1021 ggtgctaata atgcccctaa gttgacaccc atgtaaaaaa tcgaaaatcc tgcatctctt
     1081 cgcaagtcag tctttgaata aagatgtccg accatgccag aaacatttgg tttcaaaaag
     1141 gcggttccga taataatcaa tgccatcgaa acaaacaatg tacttacacc aaatggtaaa
     1201 gccaagacga tgtggccaag cataatgaaa actccaccga agaatacagt gcgttttgct
     1261 cctaacactc ggtcagatac ccatccgccg acgatactag acatgtagat caaagatccg
     1321 tagatcgaca tgatagctaa tgctgttgct cgtggtaatc caagtccccc gttggcaact
     1381 gtatcgtaca tataatagat aagtaatgca cgcataccgt aataactaaa tcgttcccac
     1441 atctcagtga agaacaaagt tgacaatccc ttcggctgcc cgaagaagcc cttgtcttgc
     1501 tgtttttcca taatctatac cccaattctt taaattttca gaaaatatta tacatcttta
     1561 ccgaaaaatt taactaaaaa acttatttaa gaaatataaa ctaattttct ataaaagcaa
     1621 gtaattttta atggcaatat cataaaaaaa agaagataga gatttaataa ttatatatca
     1681 gctgtttttt tcaaataagc aaaaattcct aaaacacaac aatgaaagcg ataactaaga
     1741 aaatccttac ataacgattt ttcttattaa aattgttttt tgaacttcgc ttattttttg
     1801 tgagcatatc tgtttactta ctttttgtaa ggtgctatac ttcatttcgt aatcaattaa
     1861 aaaaatgcaa aacgcaaatc aaaggagaaa ttttattatg acaactttta ctgacacttt
     1921 gaaaaaccgc cgttcaatct atcatctagg acgtaatgtt tcactttcta atgaagaatt
     1981 aacaactttg atcaaagaag caattaaaga aagcccaact gctttcaatg ctcaatcaac
     2041 acgcgcagtt atccttttcg gagatgcaca tgaaaaactt tgggaaatca ctgaagaagc
     2101 acttcgccca ttgactccag cagaagcttt cccaaataca caaaacaaat tagctggttt
     2161 caaaaatggt tatggtacag tattattctt caaagatact gacgtggtaa aaggtctaca
     2221 agaacaattt gaattatatg cagacaactt cccagattgg tcagaacaat caaacggaat
     2281 cgcaacagct aatacttggg tagcattagt tgataaagga ttgggcgcaa acttgcaaca
     2341 ttacaaccca gttattgacg aagcagttgc aaaagaatgg aatatccctt caaactggaa
     2401 actacgttcg caattagtat tcggttcacc agaaacaccg gctggggaaa aagaatacat
     2461 gaacgatgcc gatcgcttcc gcgtatttgg ataattttat ttgaaataaa aaacagaggt
     2521 tgtgacaaac atcttgtcgc aacctctgtt tttattctgg atcaatcata atatcaatct
     2581 ctgcctcatc gtttaagcgt tgggacaaaa atggaactaa ttcttctaat gatgcagaaa
     2641 atttcagcat cggtcctcgc catccgtttc ggaaaaaatt catttttacg attttagaac
     2701 cttttggctg atataataca attttattga tctcagaaaa aggaacacct tttttgtcaa
     2761 agctattcaa aacaagtcct tcttctgtga ttcctctact gtccaacaaa aaactaataa
     2821 aaatcattgc tgacaagatc ccttttgcca attcatctgc tgtaggatga ctgatgagtg
     2881 tataccaaat gactagtgac actaagaagg gtatcaccaa gtagacccat cgatttcgca
     2941 cagtccgata aataatttct tttcgaacca gccaaagaaa taaaaacatc acaacaacga
     3001 ataaaaacaa tagaaccgta aagaatgtta ccatgacaac tcgcctcgct ttttcttctc
     3061 cagaaaatag gaaaagaata ctgatttacc ttctcaaaga aattggactt gcagcacgcc
     3121 gcacgtccaa ttgttttctt tattcaaatg tatcatattt tgcaacaacc atgcttgctt
     3181 tttcatctaa taattcttgg tcctctgcag cacattgggc aactttgacc acggcgcagt
     3241 ttgtcatttt tgatacaact tcaccaatga ccgtttttgt aaaaccaatt ggtttgcatg
     3301 catattgttc tcctaaatta atcatttctt ccgtcatcaa aatcctccta aactgctgga
     3361 acttttctcc acattaccac tgctatttct ttggagattt aactcattga tttttattta
     3421 cagttaaaaa tcaaccttac aggcattata gcgtactgtt ttcgttttca caattaaaac
     3481 agctgttgta tttagaagaa tttttttcaa aaaattaaaa catattcctt aaaaactaat
     3541 tatttcctac atattaaaat ataatacttc catttccaat aaaaatacat ttataataga
     3601 aaagataaac agctgaaaag ggagatttca aatgaagaaa aaaacgttca aaaaactatt
     3661 gtttctaggg ggcacagctg ctcttttatt aagcggtaca agttattacc tacatatcca
     3721 ttctccagaa catacaatga acactgcaca aaaaagttca acacaaaaaa cgaaaaagac
     3781 aaaagagaaa gcagaagttt tactagatgt tccattagag agccagtttg attctccttc
     3841 tttagaaaat ggctgtgaag tcacttcgct ttctatgctt ttatcttttt atggttatga
     3901 aacaactaaa aaccagttag ctgagcaatt ggattacgtc cctgttttca atgcagatgg
     3961 gactcatggc gatcctaatg aaggatttgt tggtgatatc agtggcggag actgggctat
     4021 ggtcgtctat gttcccccag ttgcctccct tgctcagcaa atcgtccaaa cggattatca
     4081 cacttttcca aaaaccgatg ctcaactcga tgatatcaaa aaagcactat ctaaaggaaa
     4141 tcctgtctgg acttctgtga ctatcaattt tgaagtccca gatgaaactg attttatgac
     4201 ttggaccaca aataatggag aagtaagagt cactcctctt gttcatgctt gtgtagtcac
     4261 tggatatgac aaagaaaata tttatgtcaa cgatccctat ggtgtaaaaa atcgagcagt
     4321 accgatcaac gatttttcgg cgattttcac tgcaatgggt ggacagatgc taactttgga
     4381 gaaaagctag taattcaaac aaaaatccct tatactcaag ataccaaacc tttgaaggga
     4441 gcgtagataa tggaaaaatt cacacataaa aaaatggatc caaatgaaat tccgattatt
     4501 tttgtccgtg actgcaaggg aaatgttcaa ggtaaagtct ctattaatga gtggaacgag
     4561 cgtcgcagac ctgctaccct caatgaactg gaaatcaaat tgtatcgtca atctcttgtt
     4621 tattacgcag atcaagagta cgagaaagcc accgatttat tgaaatttct aattgctcga
     4681 acagagtata ctcgctttga atatattgaa cgtttagcaa acatctatca tattatgaat
     4741 gaacctgtca aagaatatca gttattggac accgtcttgt cagtagcaga actgattgcc
     4801 cttcctgctg gattagaaaa gaaactagta cgccgccttt tacgagtaaa gcaacaacta
     4861 tccgatcaag aaaaataact tgcgtttttt taggaaagtg ctatgattat tttgttgaat
     4921 aaatgggatg tagccaaact ggtaaggcac ttgactctga atcaagcaat tgtaggttcg
     4981 aaccctgcca tcccaatttg atgtgcttgc tgaaaaaatg aaccccctgt aaaagaacaa
     5041 tctttttgca gggggattat tgtattattt ttactacttg tatttagttt acataattaa
     5101 attatgaata ataaaatcgg gcgtattctt aatacaaaaa ctgatttacc caataattgc
     5161 taatgctttc tccggaactt tttctctagg aacttcctca tacgtttcta tgtgtgctcc
     5221 tttattgcta attttcaaat aatgattttc ttttaacaca gaaagaccat taaattcaac
     5281 cgttcgttct ttcccattgg catcagcagc tttctgcaca taccttgctg taccatattc
     5341 atttacttcc tctggttttt gtgtctttac atagacctct cctttttcaa ctaatggatt
     5401 tagctgatca agtataccag ggatttctcc ataacttcct tcagtataat atttcagtcc
     5461 aaatagcaaa ataccactaa tcgccgccag tccaatcaaa tatttaatca ctttcatctt
     5521 tctacctcct tgttatatat tcagtatatg ggtcagttaa agaaattcca tccgtcccaa
     5581 gttggagatt tttctcctac tttagaagcg agaatcgagt gtttttttag taaaaatgat
     5641 cgttatttga tattattgac gtgtggataa atcagttttt ctcgttttgt ccatgtaaaa
     5701 aatcatgttg atagcaaagg atgtgttcaa aatgaatcaa gaagaattat ttcaaaaagt
     5761 caaggaaatg attaagaacg gcaatttcga tggcgcaaaa cgatttatcg aagaacataa
     5821 agaacaatta ggaccttata aagagaaagc ccaaaatctt ttaaaagatg taaatatcga
     5881 cagtgtcaaa aacaaattta aaaatctatt caaataagta aaactttcac ttttgtaaaa
     5941 tcaaaggagg acaatgctgc tgcatcgtcc tcctttggtt cttttctgaa tacttcatac
     6001 taaaataaac gtgtcggatc gtaatgataa gtcacattgc cgttcagtga ggcttttccc
     6061 accacatatt tacgattctc caacttcagc cacgcttctc gaaaagccat taattcttct
     6121 ctttttacat caatcttttc gatttttcca tcgatcaaat cttgaataag ttgttcatat
     6181 ggattcattt ttttcctcca tctgctgtca atcaataagt tgtaaaaata ggttcatatg
     6241 cttttttggt atctagatct tctctgactt tgactgtcgt ataaataatt ttttctactg
     6301 ggatactata ataacttcct tcaccattat tgaatcggtg aacgtctttc tttgctaaaa
     6361 taccatttat tttattcgtc agtacacgtt gttcgacact gttacttaca acatagtaaa
     6421 tcacccgaat attattgatc aaatgcaaat cgatttctaa cactacatga tccatgaaaa
     6481 tcccactcct tctttcactt tgattatagc aagtttctcc tctaatttca aaatcgatac
     6541 agattttacc ggataaatcc acaaaactgc ttgcgccatt tcgcacaaag tgttattttg
     6601 tatcatggac tttatttatc ggaggcaata gtatgatcgc gatcggtcaa tttgtttttt
     6661 atattccttt ttttattatg ataagcattc ttttctatta cataaaatgg acaaaaaaga
     6721 agttttcagt tttactggcc tctttacctg ctgtatattt tacttatcaa attttttctt
     6781 ttaggcattg ggaaacaacg tctgtattaa taacacacat catcgaattg acgctttcag
     6841 taatttttct tattatttgg atctattttt tatataagaa tcagaattga atccctcgca
     6901 tgtttaaaaa gaaaacgatt aaagatgcag caaatttctg ccgatcttta atcgtttttt
     6961 ctattctgtt ataccaaaaa aatgtttgaa tcggtgaagg atcgttcctt gttttaattc
     7021 tataaattct tgtgcgatcg ggtacttttc ttccaaattt tctttgttct tttcgatcag
     7081 gcttttcgct tcttcatatt ttttatctgc acatagtgct tttacttcct gtaatacttt
     7141 tcctgcttcc atttgcctca ccctcttgcc attttattgc tttaagtttt atttaagtta
     7201 tacgcattat tctagtttca tcccaaataa ccttttttca tttttactcc tcgaactaat
     7261 cagttttcta aaggctgatt ggttcgtctt ttttattttt cctccatttc attctgctct
     7321 tctgttaatt tatctaatgc tttgattgat gctgcggctc ttgcataatc atagctgtat
     7381 aattccataa atttatcagg cagaacaaac cacgctggat gataaccgtt agctgtgaca
     7441 gggaatcctt tatcttgttg gttatctcca tcccatctca gagcaacacc tttttttcct
     7501 ttccacttta ctaaagcgat cgagtatccc ttctttgttt gtgtgccgtc ttcaataatt
     7561 gctaaaattt ctattttttc ttttggcgca cggacttctt gaggacgaac cattttctat
     7621 tcctccctta tctcattact tcacgaccaa cacactgcaa ggggcatgtg atacgacata
     7681 agaagcggtc gatccaacta atgcttgttg tatagcacct tttcctgtcg ctcccataac
     7741 gatcaaatca atattttctt gtccagggat gacattggca atcaaatttc ttggatctcc
     7801 agtttcaact attgcgtgga tctcagcaat gccgtactct ttggcatcat tgattttttt
     7861 cagcatggct acttctgttc tttgtttttc atctgcatag atttttgaaa aggcataggc
     7921 actatgggtc agctcaactt tgttgatgat tgacacgata aataagtggg cttcattgtc
     7981 ctttgctaag tcaagggctt cagcgaacgc tttgatcgat tgtcttgatc cgtcaactgc
     8041 taccatgatg ttctggtatc ttttactcat tggaaccgcc tcctttttct tttattgtaa
     8101 catctcaagc aaaaatacaa aaaatatacg caatatgtaa ataaaatgat gaacaaaagc
     8161 aatttctttc aagttattta tacatttctt ttctcatcag aacacctgtt ctaatcccat
     8221 tatttctgca ttatgtgaaa ttcctcatca tttttcacat cgagcgaaca tcattctgtt
     8281 acaaaaaacg tggatttgtc ataaattgtc atgcttcttt tacctatgaa atattttcac
     8341 gtgttaaagt attcctcgtt gaacacaaca aataaaactt tttaacgaat aaaggagatt
     8401 tttcatgaca tcacttaaaa ctttactttt tggaacaact ttggctgccg gcgctgcatt
     8461 cttcatggga acgactgctc atgcggacga agcttatacc gttcaatcag gtgatactct
     8521 atcaacgatt tctcaaaaat acgttggtga taactccttg atcaatgcca ttgcagaatc
     8581 aaattc
//
LOCUS       DAXLPC010000102         8561 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.103, whole genome shotgun sequence.
ACCESSION   DAXLPC010000102 DAXLPC010000000
VERSION     DAXLPC010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8561
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.103"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..303
                     /locus_tag="ACF3UE_002382"
     CDS             <1..303
                     /locus_tag="ACF3UE_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635749.1"
                     /translation="FMERSSHAMILTFLWLLFTRIYIFLMSLKPPKSISLCLVINGIF
                     LLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYIGYFPNKNNNFYFYRNKL"
     gene            complement(429..1106)
                     /gene="nth"
                     /locus_tag="ACF3UE_002383"
     CDS             complement(429..1106)
                     /gene="nth"
                     /locus_tag="ACF3UE_002383"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFD3635750.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(1113..1811)
                     /locus_tag="ACF3UE_002384"
     CDS             complement(1113..1811)
                     /locus_tag="ACF3UE_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFD3635751.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2079..3263
                     /locus_tag="ACF3UE_002385"
     CDS             2079..3263
                     /locus_tag="ACF3UE_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFD3635752.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3269..3712)
                     /locus_tag="ACF3UE_002386"
     CDS             complement(3269..3712)
                     /locus_tag="ACF3UE_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFD3635753.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(3938..4225)
                     /locus_tag="ACF3UE_002387"
     CDS             complement(3938..4225)
                     /locus_tag="ACF3UE_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFD3635754.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            complement(4396..5748)
                     /locus_tag="ACF3UE_002388"
     CDS             complement(4396..5748)
                     /locus_tag="ACF3UE_002388"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFD3635755.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSDPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQEALGEIETAQ
                     "
     gene            complement(6020..6466)
                     /locus_tag="ACF3UE_002389"
     CDS             complement(6020..6466)
                     /locus_tag="ACF3UE_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFD3635756.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            complement(6702..7628)
                     /gene="cysK"
                     /locus_tag="ACF3UE_002390"
     CDS             complement(6702..7628)
                     /gene="cysK"
                     /locus_tag="ACF3UE_002390"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFD3635757.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            complement(7768..8561)
                     /locus_tag="ACF3UE_002391"
                     /pseudo
     CDS             complement(7768..8561)
                     /locus_tag="ACF3UE_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
BASE COUNT         2323 a         1752 c         1424 g         3062 t
ORIGIN      
        1 tttatggaaa gaagctctca tgcaatgatt ctcacttttt tatggttgtt gttcaccaga
       61 atctatattt ttctgatgag cctgaaaccg cccaaatcca ttagtttatg tttagttata
      121 aatggtattt ttttattatc acttatcatt tttattacac ctttagatag atacgtcact
      181 tatttatata atcctttgga atactggact tattttatag gtatattgga aggcattatt
      241 ttctacatcg ggtattttcc caataaaaat aacaactttt atttttatcg caataaattg
      301 taataagtta ccatcctagc tactgagtat gtacatttac tttttcatgc aaaaaagata
      361 aacgaaacag cttttctcca taataacaag ataattcata catttatttg caattaaaga
      421 aaccacgtct acaggcgtgg tttctttttt agcgcctttt cttttagacg catccgattt
      481 ttcccatctt gacatattga tagcaaagga catacctcgc acttgggatt tcttgccgtg
      541 caatgatatc taccaaaaaa aatcagtgta tgatgtgtct ttacccataa ttcttgtggt
      601 actttccgca tcagtgtttc ttctacttcc atgaccgtag catctagttt gcagatcctc
      661 aggcgttttg agacacgttc cacgtgggta tctactgcga ttgctggtat cccgaatgca
      721 tcccccaata cgacatttgc tgtctttctg cctacaccag gaagagacat caattcttct
      781 cttgacgttg gcacttgccc atcgaaacgt tcaatcagct gctgtgcaca cgctttgatg
      841 ttttttgctt tatttcgata caaaccaatc gtttttattt taagaatgat ttcatcgatt
      901 gaagcttctg ctaacgcatc gggtgtcgga aaagaggcaa acaaatctgg cgttgcttta
      961 ttcactgata catctgtcgc ctgggcactt aagatcactg caatcaataa ctcaaatgga
     1021 ttattgtgct tgagttctcc atgtgcttcg ggaaacattc catacatcgt ttctagagct
     1081 tccattgttt tttgtttgct taacatattc cgctactcct ccaaccaatt tttcagtgag
     1141 actttcggca attcttcttg ttgagctgac tgttctactt ctctttgaag aagctgctgt
     1201 tttcttcgtt tttggtcttc ttccacttgt tgttttgtac gtagattttt tctttcccac
     1261 gatagcaaaa tgcggtcaac gtaattaaaa ctataagcct gatttaatac ggcttcccgc
     1321 agtgctagct tcaaaatttc cggctgataa tggtcttctt ctagccattg tccgatccgc
     1381 tggaactcga tcgaagaaag cgggcgtcca aattcttgtt caaataattg atacactgac
     1441 tggatttctt tttcttgtgt tttttcttcg tatttttttt cttgtgtttt taaatactca
     1501 cctaatagat catagatggg gtaaagatta tatcgatctg cttttttacc gttgacaatc
     1561 gtcgtttcta tcttgataaa tccatttgtt acgagacgat ccagtatttg aaaaatctga
     1621 tcttgtttga ttcccatatc catagcaatc atctgcaaat cagggaaagt atctccttca
     1681 agctgtgcca tatgcaactg tagaacaaat aaaaattctt cagattgtag accgatccta
     1741 tgataatttt taagtaaaag attagatatg actgtttgtc cagcgcttaa gtaattttct
     1801 aaattcaaca tgatttctcc tccgctcaat cacagtatac gtaaaaaaaa catgggaagc
     1861 aagaacaggt ttcttttcta tttacttcac tgatcggtca gatttacaat gtcgtctact
     1921 tgatttttgt ttgttcatgt ttttgatgcg tatcttcact tttcggaata aataaattaa
     1981 gtagatttcg ctgttcctta gaatgttgac aaggaaacaa aattactata cactattttt
     2041 gtttccaagt taacattatt gcataaagga gtttttacat gtacagtttc acaaataaac
     2101 attctaaagt ttttggatac gtctctgtct tattcactgg attaggattt actatcgtca
     2161 gtcctgtact tccgttttta acgctgcctt attctcactc catacatcag caagctttct
     2221 atatcacttt gctcatgtct gtttatgctc tagctgcctt cttatctgcc cccattctcg
     2281 gtagcttaag tgatcatttt gggcgtcatc cgatccttat tatcagttta ttaggatcaa
     2341 gtatcggata tttgcttttt ggtttaggaa attcgatatg gatgttgttc cttggtcgta
     2401 tcattgaagg attgacggca ggagaaatct ccaccttata tgcttacttt gccgacatca
     2461 cggaacctaa tgaaagaacc aaagtttttg gatggatggg tgctttagtc ggtataggaa
     2521 caacgctggg tcctattata gggggtctat tagctgagtt ggggaattct gttcctatat
     2581 ttattggagc actctttact ttcttaaatg ccgtttatgg ctacacattt atgctagaaa
     2641 gccttccaat aaaaaaacgt tcagtagatt taagtttctc ccatgtaaga ccttttcacc
     2701 aattacaaca attattcaag atttcatccg ttattccttt attgacagca ggttttgctg
     2761 tttggttggc agctggctct cttcaatcta tcttttctca attttcgatt gacgcctttc
     2821 agtggaaggc tgggttggtt ggtttaagct tctctttgat tggaatcttg gatactgtct
     2881 cgcaattgtt cattatgcct cgattgctca aaaaattttc agaacagcag atcacaagaa
     2941 tagggatgtt cagtgaaatc ctcgcctatc tattcatcac attatctgga attcttctac
     3001 tgccgatttt gtttttattt gggattatct gttatggttt cggtgattct atttttactc
     3061 ctgtattcaa tggccaacta tccaattctg tctcagataa ccagcaaggt cttgtaatgg
     3121 gcggtaccca aagtatacaa tctctatcgc gcgtcatcgg cccgctaatc gcaggacagc
     3181 tttatgctgc agcaccattt cttccgacgg tattcggatt tttgcttatg atttttgcct
     3241 attatcacta caataaaaaa tagtagcttc atttgctact tcgtataaat tctctgtatc
     3301 gaccgataaa acgaaatact gtgtcaaatt cttcttttga catattttca aatacagtag
     3361 catctcgctg tacccatttt tgatggagtt gctcgtgtct attccttatt ttttgtccga
     3421 ttggcgtcaa ttgaaaatag atttcttttt tattctcttc gctttgataa gtgtttatga
     3481 tccctctagc tatcagtttt tttgttagct tactgatggc tcctctagtc atgtaactag
     3541 cattcgctaa ttttgtcacg ttaggatcag ggattttccc gatatgttca atcacttcta
     3601 gttcatttag agtaaatcct gcaaattctt tttccatttc tggtttatta cgatgaataa
     3661 tctcattagc taaatccaga tattcttcta ttagcagttg tcttttatcc atttctacac
     3721 cttctttttc tttcattata ttgttttttt gtttcctatt caacaaagat aaaaatattt
     3781 tgtaggaaaa cccaatctga aaccaagaaa aaaaggggtt gacaaagctt gtcataaccc
     3841 ctttttctga ttaaaagata gtaaagagac agtcatcggt aattgtgatg attttttgtc
     3901 atcacttaag gatgagcggc cttttcaaaa actgtcttta aagatcatca tcagtttcta
     3961 gcacatatgg ctgaccttca tatgtgtact ctgtattcaa tgtgccgtca ttttcatctg
     4021 agtagatgcg tctactgaaa ggaaaacgat gagaaacatt atctttggcg tcatttgctg
     4081 gcatcgtgta atattcctct tgcgtttcat tcaactgaga gagtacttga tctgccaact
     4141 catcaatatt gatcgttaat ttcttcgaag cacttttata atcttctaaa aatgcatctt
     4201 gttggacaaa atattcttta ttcatcttct ttctcacctt tcttttcaaa atcaaataaa
     4261 gctgcttgtt cttttatgta acagctttat ctttgctgct tattgtgaca aaaaattcga
     4321 agaaagacaa ctaattgtac ttttcacaaa aaaagacaga gggtcgtgac aaaattgtgt
     4381 cacaaccctt tttctttatt gtgcagtttc gatttcgcct agcgcttctt gtgcaagtag
     4441 gttcaagtaa ttccatgggc ggtcaaaatg tggttggaag aagaaatctg aaagtgcgag
     4501 atcttctaca gtcattttat tttgaacagc taaagacatg gtatttgctg attgtgtaat
     4561 gtcgtatttg gacatgaact gagcacctac gatacgattc gttccttttt catagactag
     4621 ctccatcatt actttttcag tagttggcat gaactctgga cgataattat cttcaaatac
     4681 agtcgcttgg acttctagat cgttcaaagt tgcgctttct ttggtcacac ctgtcgaacc
     4741 gatcgtccag ccaaataggt aaagtcctga agttccttga gtaccacgat acgccatttt
     4801 atgatctgtc aagttatttc ccacaagtaa accttgacga acggcatttg ttgccaaagg
     4861 aatatagttt tgcgtgccac ttggattgta gttgactact gcagagtctc cagctgcaaa
     4921 aatgtctgga tcacttgtct gcatgtattc attcactttg attgccccgt ttggcagtgt
     4981 atctactttt ccttcgatca gttttgtatt tggacggaag cccacacata aaatgaccat
     5041 atctgtatca aatgtatctg ttggtgtagc tacttgtttc acttttcctt cttcatctgt
     5101 gataaattca gtaacatttt cgcctagcgc aagagtaaca ccgcggtctg tcaattcttt
     5161 ttctaagata tctgtgaatg gtttatctag atatttattc aagatgcgat ctaatccatc
     5221 aatcaatgtc acttgttttc cagattcgac aaaagcttct actaattcaa taccgatata
     5281 tccaccacca acaattacta cacgttttgc ttctttcgct tgtgcaataa tttcatttgc
     5341 ttgattgtag tttttgcata ggagtacatt tttcgcatcg attccactaa tcggtgggat
     5401 aataggccat gaaccagttg tcatcactaa tttatcataa gaaaccgttt ctgtttctcc
     5461 tgttttcaga tcttttgccg ttactgtttt attttctgta tcgacgtctg ttacatcgtg
     5521 ttccatttta actgttgctc ctaatgaaga taattcttca ggatttgagt agaacaagcc
     5581 tgctgggtcc tttactactc cgccgacata aagtgcgata ccgcaagata agaaagaaat
     5641 attgtcattt ctttcatata ctgtcacttc tgcttctgga tgatttttta aaatactttt
     5701 tacagctgca gtacctgcat gagtacagcc aattactact actttcattt atggtccctc
     5761 cgattaacat tttgtccttc gacaaaacta ctataacaga aataaaacgg atacaacagt
     5821 ttaatgcttg tgaattcaca aaggtttgtt tgtagtttca ttccttttca agcataagaa
     5881 cccaatatct acaagattct tattgtgata atattcactt tgatatctaa gattgtgaat
     5941 aaaagacaaa aaaataaaaa agctagcgtt tttttacaca gctagctttt tttaggtata
     6001 acacttatag aaactgtttt tacatttgcg ccttttttgc tgactcttta caatccggac
     6061 agagtccata caattccaac cgatgttcat taatctcaaa atcagtcagt ctgctcgcag
     6121 ccatttctat atcttcaagc cctgggtaat gaaaatcaac aatcttaccg cagttttcac
     6181 aaattacatg ataatgacgc tttgaactga aatcaaatcg gctagaagca tcgccgtact
     6241 tcatttcttg aacaaatcca atcgaagtaa ataagcgaag gttattgtaa acagtcgcaa
     6301 cactcatatt tggaaaccga tgttcaagtg ctttataaat ctcatcagcc gttggatggg
     6361 aatgatgttc aatcaaatat tctaaaaccg cgtaccgttg aggtgtgatt cgaatgttct
     6421 ctttttttaa cttttcgata acctcttcga ctaacttatt ttccatgtaa acaccccacg
     6481 ttgttattct cgtcttatca tactattttt acattttaaa atccacttaa catgaaaaga
     6541 aaattcaatt ttattgtatt ttaatgaaaa aagacgtaaa acagtcgcgt tcactatttt
     6601 acgtctctat tcaaataatt tttctcatca taaatttttg tgtgttcttt tcatctttaa
     6661 aagtttttta cataaaccta tctggagaaa aaccaagtgc cttatatctc ttggtaaagg
     6721 gctgtagata aataacgttc accattgtcg ggaaccacag ctaatacctt cttgcctttt
     6781 cctaattctt ttgcgacttt tagcgcggca gcaattgcag cgccagatga gatgcctact
     6841 aaaatccctt cttttcgccc aacttctcta gctgtttcca tcgcttcgtc tccactaata
     6901 gaaaggactt tatcatacac agaagtatcc agtgttttag gaacaaaacc tgtaccgatt
     6961 ccttggattt tgtgaggtcc cgcttctttc ccttctaaaa tagcagattc tgctggttct
     7021 accccgatta attcgatttt cggatacaca cgttttaatt ctcggccagc gccagtgatc
     7081 gttcctcctg taccgatacc tgcaacaaac gcgtccaagc catttactcc aaatgcttga
     7141 tgtatctcag gaccagtcgt cttctcatgc acaagaggat ttgcttcatt ttcaaattgt
     7201 aatggtaaaa agtagccgtt ttcttttgcc aaacgttctg cttctctgat tgatccagaa
     7261 ataccatccg caccaggagt caaaatcaac tctgcgccgt accctttcat caataaacgt
     7321 ctttcgatac tcatcgtctc aggcatcacg atgattactt tatatccttt tgcaactcct
     7381 accatcgaca atccgattcc tgtatttcca gaagtaggtt caatgatagt atcacctggt
     7441 ttcagtagac catcgtgttc tgctttttct atcatactta aagcaatacg atcttttaca
     7501 cttcctcctg gattaaaaaa ctcaagcttt acaaaaacat ctgctgaatc ttctggtacg
     7561 attttattta atttgacgat tggcgttttg ccaatcaatt cggtgactga gttatagata
     7621 gctgtcatct tcaattcctc cttgtctttg ctcttcttac ttatcataat acaatctgtt
     7681 catttatggc gagtgattcg tctttgacta gcaaaaaaaa gacaaagata taccatatat
     7741 ggtagtttct ttgccttttt atctaaatca aacgtttagt tcttgaccaa ctaataaaga
     7801 ataactggac atagacatgc catttttcgc cattagatca tcaacagaca tgccaaattt
     7861 ttgtgcaata tcccatagcg tatcacctga cacgactgta tatgtctgac cattatttgt
     7921 atttacatct gttgttgaag atgatgacgt tgaagtcgtc gtagtagtcg ttgttgttgt
     7981 acttgtggta gccgaacctg ttgatggcgt atcaaaacgg gttaaattat aagtattaat
     8041 caatgagttc aatttggccc cataatttgg atcggtagca taacgacctg tcaagtacgc
     8101 tgttgcatca taaaaacttg ttgtattgct tttccacacg ccagcataat gataatcgcc
     8161 cgtggaaaaa ctggttgaac gaagaacatt cgcatggtct tggaaggatt cccaataaga
     8221 agaatatttt cggaatggtt cattcatcgt tacccattgt ccgttacata ttctttggtt
     8281 gccatataaa cgacctgtcc gttatagctt cctttcacac cgaatagatt ataatttggc
     8341 gcactagcta atccggaagt gccatatgca ctttccaaca acgcttgagc gatcatgact
     8401 gaagcataca agtcattact tgcagcaact tctgacgcag accagccgat ttgatcgata
     8461 aacgcttgag gatcagcaac tgtttgagat ccttgttcat ctgcatgaac atgttgcggt
     8521 accgctgtaa ccatcatcgg cccaactaaa agactcgttc c
//
LOCUS       DAXLPC010000103         8543 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.104, whole genome shotgun sequence.
ACCESSION   DAXLPC010000103 DAXLPC010000000
VERSION     DAXLPC010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8543
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.104"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(81..467)
                     /locus_tag="ACF3UE_002392"
     CDS             complement(81..467)
                     /locus_tag="ACF3UE_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635758.1"
                     /translation="MIDKQITNILQSYKKQQIFKIEDFLLSEIDEDNLQETIDFVVSD
                     DVSKKINFSDELYDGNEYEGVFLEGNQYLLSSSEGKVMIIDMLSEAHGVNIKDTRVQF
                     DEEKFIKLITNKKEILNWIKNYKVDK"
     gene            complement(484..1551)
                     /locus_tag="ACF3UE_002393"
     CDS             complement(484..1551)
                     /locus_tag="ACF3UE_002393"
                     /inference="COORDINATES: protein motif:HMM:NF013630.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3635759.1"
                     /translation="MAKPSTPATYKVKAGDSVWGICEKYGLSISKFVQWNKIKNNTIH
                     PGQKLTVKQPVSSGKPTTKVPASTNPVTHKVSYGESLWLISSKYGVTVDELRKQNGIK
                     GDLIHPGQVLVVKKGMTTSHSTPVGKSGTSYTVKAGDSVWLIANRYGVSMDDLVKWNK
                     IKNYTIHPGQVLTIQTIVSTPAKPAITTTPKVKAKPAITTTPKAESKSGVTTTPKVDE
                     KPVITTIPKVKEQPVVTTVPKTESEVLVEKASGDGSRLDINIKNFEIKNKHLNSSTAK
                     RARKFNVSSAEEANKIVQDALKNGKLVEAIPNGVGSQGQNSFSSIIDTGKVIGTKGET
                     HIKIVYDELKNVWTTYPVPKP"
     gene            complement(2073..2585)
                     /locus_tag="ACF3UE_002394"
     CDS             complement(2073..2585)
                     /locus_tag="ACF3UE_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016617327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635760.1"
                     /translation="MKIKSYEDKLVKDDIEVDYYVPITVSFPENDDKYNLGEFYYYRF
                     VNEYESFVEIKINSVTQKIVEVVFTSINDIEDSNLFIGEYAEKNPVIQTDIFDENSII
                     TKESGFKISREHKKLCFKLDKEKMDSVVKMSNHVSLFLNEDSEIIGLEFSSFSDNEWA
                     ELNESIKSTT"
     gene            complement(2604..5567)
                     /locus_tag="ACF3UE_002395"
     CDS             complement(2604..5567)
                     /locus_tag="ACF3UE_002395"
                     /inference="COORDINATES: protein motif:HMM:NF013630.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFD3635761.1"
                     /translation="MLKKVLRFGVCISIWLVTSSTFVPSMIAVADSVAIQETIASDSE
                     GEEKLTERSDDASDGQTEKVEVQKTETTQTTVSSSSDESSDLTQSSEETAPEEVDEST
                     EESSDPQEQTISHEEETKEAVDSSTIDFEGTRSSESFGKHTSPSIDKPNEKIAEPVSS
                     NEGAVVSRRSRRDLSAVSSNHPEEEPVVAFDEKAFDAAIDQYIDHATEEELGLVINSS
                     NEKELADALEYLLLNQLDESFGVEELDELKKFLTADEIERLENESSLETFEQLLTQYY
                     NDREQKLEEGAAFSDFFLASTDEEIDRMLEVKDEQALEQVISEISASRNSQTSGKRNK
                     RFLVIPLLVKGAMLVIGAGVAAYSSHQFYKTMEAQRAEKKRMVERWRYHEQQAQKRHQ
                     AAQQARAKAVARAKLQAAARAKAQATQRARAQAAAKARKQAQNWAKQQAAARARAQAA
                     ASARRKSNASYVPPVTRPKPVIKAQPKVPAKPVAKPVTKPTSPAKPKPTTTPKNTMHQ
                     VRAGESVWSISHKYGISMNDFIKWNKIKNNLIHPGQQVIVKQPASTSKPVSKPATKSS
                     TPATYKVKAGDSVWGICEKYGLSVSKFVQWNKIKNNTIHPGQVMHLQEPKPASKPAPK
                     TSPTTNTTYTVKAGDSVWLIANMHGISMNDLVKWNKIKNNTIHPGQKLTVKQPVSSGK
                     TTTKVPASTNPVTHKVSYGEPLWLISSKYGVTVDELRKQNGIKGDLIHPGQVLVVKKG
                     MTTSHSTPAGKSGTSYTVKAGDSVWLIANRYDVSMDDLVKWNKIKNYTIHPGQVLTIQ
                     TIVSTPAKPAITTTPKVESKPAITTTPKVESKPGVTTTPKVDEKPVITTLPKVKEQPV
                     VTTVPKTESEVLVEKASGSTGTVWDDIKGTQPPREGTTIPKSFEIIVNGEKLWVNPNG
                     TKHMVEYSTRNLSHGQKLTEQQLLRSFQGAVEQATSTGIKFETKIIIDNWELIFSPAR
                     EAGQLPVIKHAVYLP"
     gene            complement(5813..6280)
                     /locus_tag="ACF3UE_002396"
     CDS             complement(5813..6280)
                     /locus_tag="ACF3UE_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635762.1"
                     /translation="MKKSLIVLIVGLSIFGSVLFIGNSLFSNKDVTEQSPASTTEEVS
                     PELLLETDVLDTKKPETIPSENELYQGDLSFEYADPEKPYVLTIRFIDKANHEYVGPD
                     KKPLKREKELILGKAKGVVHVVVKANRSMLTHIQKLKDIQVSMTLNERNEKTE"
     gene            complement(6302..6454)
                     /locus_tag="ACF3UE_002397"
     CDS             complement(6302..6454)
                     /locus_tag="ACF3UE_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002392643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635763.1"
                     /translation="MKKKGIPYSPKPRNAFERGLFKYFEGERDQEEKEKNQKKKSSQE
                     KENIEK"
     gene            6955..7296
                     /locus_tag="ACF3UE_002398"
     CDS             6955..7296
                     /locus_tag="ACF3UE_002398"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635764.1"
                     /translation="MKANTPYKVGDIFYSSWGYEQTNVTFWQIIKLTKKTAWFRPIKK
                     QTVKNYTSMSGETMPIPNEFIDYPLARTKDSIVRKRINPALYPNELYGNRSWDTFYRY
                     DNQPVYESSYY"
     gene            7489..7782
                     /locus_tag="ACF3UE_002399"
     CDS             7489..7782
                     /locus_tag="ACF3UE_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635765.1"
                     /translation="MLRTNAIPIVDSYDRNTNNYLGSFEQTDENILNYVAGLSPFESV
                     RLVEHTTDTLILTTIGYFFDQVSDQQWLQQILPKLIAKQTGKSTIEAVKIFFY"
     gene            7838..8386
                     /locus_tag="ACF3UE_002400"
     CDS             7838..8386
                     /locus_tag="ACF3UE_002400"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635766.1"
                     /translation="MSILQPFGEPIERTEFIQHYMKLFVQVIKHTHQIDEFYSKEIEY
                     LLAEKQKIALLYDYFVEMYDRAPDYFYLSDTLTTNFLAKEHLFASHTKNLMCVEHFVN
                     TYLHLLKIQKICTFEAFQTDYLFILDREAYHAKLAFEKQNQAIEGYPELRIQNNSFLQ
                     QRLLKQLINGFHQRNKAYQKDQ"
BASE COUNT         2423 a         1678 c         1407 g         3035 t
ORIGIN      
        1 aacttgatta gtgagtgtat gcttactatt caaggctttg ctattcgacg ccaatcgaat
       61 agtaaagtgc cttttttatt ttatttatcc actttataat ttttaatcca attaagaatt
      121 tcttttttgt tcgtgattag tttgataaat ttttcttcat caaattgaac tcgagtatct
      181 tttatattaa caccatgagc ctcacttaac atatcaatta tcattacttt tccttctgag
      241 ctagatagta aatattgatt accttctaaa aatacacctt cgtactcgtt cccatcatat
      301 aattcatcac taaagttaat tttcttacta acatcatcag aaactacaaa atctattgtt
      361 tcttgtaaat tatcttcatc aatttctgaa agtaaaaagt cctctatttt aaatatttgt
      421 tgttttttat acgattgcaa aatattcgtt atttgtttat caatcacttt gcttacctcc
      481 tatttaaggt tttgggacag gataggtagt ccacacattt tttaattcat cataaactat
      541 ttttatatgt gtttcccctt tggttccaat aactttccct gtatcaataa tactagaaaa
      601 agaattttgt ccttggctcc ctactccatt tggtatagct tctacaagtt ttccattttt
      661 taatgcgtct tgaactattt tattagcttc ttcggctgaa gaaacattaa actttctagc
      721 ccgtttagca gttgaactat tcaaatgttt attcttgatt tcaaaatttt taatattaat
      781 atccaatcta cttccatccc cactggcttt ctcaaccaat acttctgatt cagtcttagg
      841 aacggttgtg accacaggtt gttcttttac tttcggtatt gttgtaatta ctggtttctc
      901 gtccactttt ggtgtggtag tcactccaga ttttgattcc gcttttggtg tcgtggtaat
      961 cgccggtttt gcttttactt ttggtgttgt cgtgatcgca ggttttgctg gtgtagaaac
     1021 aattgtttga atcgttaaga cttgacccgg atggatcgta taatttttga tcttgttcca
     1081 tttcactaga tcatccatgc tcacgccgta tcgattagcg atcaaccaaa cagaatcccc
     1141 tgcttttacg gtatagctgg ttccgctttt tcctacagga gttgaatgac tcgtggtcat
     1201 accttttttg acgactaata cttggccggg gtgaatcaaa tcacctttga tgccattctg
     1261 tttgcgtaat tcatcgacgg tcacaccata tttactacta atcagccata aagattcacc
     1321 ataagagact ttgtgggtga ctggatttgt agaagcgggt acttttgtcg ttggtttccc
     1381 tgatgaaaca ggctgtttga ctgtcaactt ttggccagga tggatcgtat tattcttgat
     1441 cttattccat tggacaaatt ttgaaatgga taacccatac ttctcacaaa tcccccaaac
     1501 tgagtctcct gcttttactt tgtacgtagc tggcgtactt ggttttgcca ctggtttgga
     1561 cgttggtttt atagtagatt atcttctgga aattctcaaa ttaacctttt acatgcctct
     1621 aaagtggata taaaattttc aactgaagaa gcaaaggtca ctaatagtaa atatgaacac
     1681 tatttttgaa tctggaaaag agaaaattaa tatgacaaat gactaaatag aagttgtgaa
     1741 ggtacttgtt ataaaacaat ttctaaaagg agcggaaggc aatgagaaaa atgattcttc
     1801 tgatccgtaa aacactataa agaaagtcaa tagatcatta gtctctccta atattgctat
     1861 tgactttctt tattgggcat gtgcttttga tagtgcccga ggaactcaca aaatacctag
     1921 taccttggat tatccctcga accttttcag cataacatgc ccaccgttta ttttagcatt
     1981 tgaatttgtt ctttcaaaat tcttttgttt catcctcaga atctagcaaa atagctgttg
     2041 aaaatcctat cttcttctca tttaaaatta aatcaagtgg tagattttat actttcattg
     2101 agttctgccc attcattatc tgaaaagcta gaaaactcta aaccaataat ctcactgtct
     2161 tcatttagaa ataaagatac atgattagac atctttacaa cagaatccat cttttcttta
     2221 tctaatttaa aacataattt tttgtgttct ctagatattt taaacccaga ttctttagtt
     2281 ataatcgaat tttcatcaaa aatatctgtt tggatcactg gatttttttc tgcatactct
     2341 ccaataaata aattggaatc ttcaatatca ttgatggatg tgaatactac ttctacaatt
     2401 ttctgtgtaa cagaattgat tttaatctca acaaatgatt catattcatt aacgaatcta
     2461 taataataaa attctcctag gttatactta tcatcatttt ctggaaatga tactgtgatt
     2521 gggacataat agtcaacttc tatatcatct ttgactaatt tatcctcata acttttaatt
     2581 ttcataattt gctcctttca tagttatggt agatatacag catgtttaat aactggtaat
     2641 tgtcctgctt ctctagctgg actaaatatt aattcccaat tatctattat tattttagtt
     2701 tcaaatttta tccctgtaga agtagcttgt tctacagcac cttgaaaact ccttaacaat
     2761 tgttgttcgg taagtttttg tccatgagat agatttcgag ttgaatattc taccatgtgc
     2821 ttggttccat ttggatttac ccacaacttt tccccattaa caattatttc aaacgattta
     2881 ggaatagtag ttccttctct tggaggttgt gtacctttaa tatcatccca gactgtacct
     2941 gtagacccac tggctttctc aactaatact tctgattcag tcttaggaac ggttgtgacc
     3001 acaggttgtt cttttacttt cggtaatgtt gtaattactg gtttctcgtc cacttttggt
     3061 gtggtagtca ctccaggttt ggattccact tttggtgtcg tggtaatcgc tggtttggat
     3121 tctacttttg gtgttgtcgt aatcgcaggt tttgctggtg tagaaacaat tgtttggatc
     3181 gttaagactt gacccggatg gatcgtataa tttttgatct tgttccattt cactagatca
     3241 tccatgctca cgtcgtatcg attggcgatc aaccaaacag aatcccctgc ttttacggta
     3301 tagctggttc cgctttttcc tgcaggagtt gaatgactcg tggtcatacc ttttttgacg
     3361 actaatactt ggccggggtg aatcaaatca cctttgatgc cattctgttt gcgtaattca
     3421 tcgacggtca caccatattt actactaatc agccataaag gttcaccata agagactttg
     3481 tgggtgactg gatttgtaga ggcgggtact tttgtcgttg ttttccctga tgaaacaggc
     3541 tgtttgactg tcaacttttg gcccggatgg atcgtattat tcttgatctt attccacttc
     3601 accagatcat tcatactgat cccatgcata ttagcgatca accagaccga atctcctgct
     3661 tttaccgtat acgtcgtatt agtcgtagga gaagtttttg gtgctggttt tgatgccggt
     3721 ttcggttctt gtaaatgcat cacttgtcct ggatgaatgg tattattttt gatcttattc
     3781 cattggacaa attttgaaac ggataaccca tacttctcac agatccccca aaccgaatcc
     3841 cctgctttta ctttgtaagt ggctggcgta cttgattttg tcgcaggttt ggacactggc
     3901 tttgatgtac ttgctggttg tttgacgatg acttgctggc caggatggat cagattattt
     3961 ttgattttgt tccatttgat gaagtcattc atactgatgc catacttatg cgaaatagac
     4021 caaacagatt ctcctgcacg tacttgatgc atcgtatttt tgggggtcgt cgttggcttc
     4081 ggtttcgctg gagaagttgg tttcgttact ggtttggcta ctggttttgc aggtactttg
     4141 ggttgggctt tgattactgg tttcggacga gttaccggag gaacatagga cgcatttgac
     4201 tttcttcgtg cacttgcggc cgcctgtgca cgagctcgag cggcggcttg ttgtttagcc
     4261 caattttgtg cttgttttct cgcttttgct gcggcttggg cacgagctcg ttgtgtggct
     4321 tgcgcttttg cacgggctgc tgcttgtaat ttggcacggg caacggcttt ggcgcgggct
     4381 tgttgtgcgg cttgatgccg cttttgtgct tgttgttcat ggtaacgcca gcgttcgacc
     4441 attcgtttct tttccgcacg ttgtgcttcc atcgtcttat agaactgatg gcttgaataa
     4501 gcagctaccc ctgccccgat taccaacatc gctcctttga caagcaatgg aatgactaag
     4561 aagcgcttgt ttcgctttcc acttgtttga ctattccgag aagcactgat ttcagaaatc
     4621 acttgttcca atgcttgttc atcttttacc tctaacatcc gatcgatttc ctcatcggta
     4681 cttgctagaa agaagtcact aaatgctgct ccttcttcca atttctgttc tcgatcatta
     4741 tagtattgcg taagcagttg ttcaaatgtc tctaacgacg attcattttc caatcgttca
     4801 atctcatctg ccgtgaggaa cttctttagt tcatcgagtt cttctacacc aaaggactca
     4861 tccaattgat tcaacaagag atattctaaa gcatcggcca attctttttc attgcttgaa
     4921 tttatgacta accctaattc ttcttctgtt gcatgatcaa tgtattgatc gattgcggca
     4981 tcaaaggctt tttcatcaaa agcgaccacc ggttcctctt ctgggtgatt tgaagaaacc
     5041 gcagaaagat ctcggcggct tcgccgtgaa acaactgctc cttcatttga agagactggt
     5101 tcggctattt tttcgttagg tttatcaata cttggagagg tatgtttacc gaatgattca
     5161 gaagatcgtg ttccttcaaa atcaatcgtt gatgaatcaa ctgcttcctt cgtttcttct
     5221 tcatgagaaa tcgtttgttc ctgaggatcc gaagactctt cggtagactc atcgacttct
     5281 tctggcgcag tttcttcgct ggactgggta agatcacttg attcatctga actgctcgat
     5341 accgtcgttt gagtagtttc tgttttctgt acttcaacct tttcagtttg tccatctgac
     5401 gcatcgtccg agcgttctgt aagcttctct tccccctcgc tatcagatgc gatcgtttct
     5461 tgtatcgcca ccgaatcggc cactgcaatc atacttggca caaaagtgga agatgttacc
     5521 aaccatatac ttatacatac cccaaatcgt aacacttttt tcaacatatt tttcttcctt
     5581 tcttcattta cacctaatta aaataacgat cattatcata ctgaaaattg tagaaacaaa
     5641 tttaaatagg tgtttaaaga aataatatca tcatttttaa tgatgataaa taacagggaa
     5701 gaaaaaaatg acctttcatt tttgtaatat gatcaagcaa ctataaagat ggaacaaaat
     5761 aaataaaccg ataaaagtag aacagatatt cccaaaacat gtctgatttc cgtcattccg
     5821 ttttctcatt tctctcattt aatgtcatgg acacttggat atcttttaac ttctgaatat
     5881 gggttaacat cgatctattg gcttttacaa ctacgtgtac gacaccttta gcttttccta
     5941 gaatcaattc tttctctctt ttcaatggct ttttatcagg ccctacatat tcatgattcg
     6001 ctttatctat aaaccgaatc gttagtacat acggcttttc cggatccgca tattcaaatg
     6061 aaagatctcc ttgatagagc tcgttttccg aaggaattgt ctcaggtttc tttgtatcaa
     6121 gaacatccgt ctctaataat agctctggag atacctcttc cgttgtgcta gcaggggatt
     6181 gttccgtaac atctttgtta gaaaacaacg agtttccaat aaataaaaca cttccaaata
     6241 tacttaatcc aacaatcaat actattaaac tttttttcat acttctctat tttttcacct
     6301 actatttttc tatattttct ttttcttgac tagacttctt tttttgattc ttctcttttt
     6361 cttcctgatc tctttcgcct tcaaaatatt taaataaccc cctttcaaaa gcatttctag
     6421 gtttcggaga ataaggaatg ccttttttct tcatacaaac acctctttta actatttgat
     6481 ctattttata ccaccacatt atcaaaataa caaatgtatt aaaaggaatt tcttattaaa
     6541 accatcttga ccttttggga gatttcagtg cgatttcttt ttattcccat acttttttcg
     6601 ttggtcgctt tcgtataccc aatctaagcg atcatcggca gtagtgcttt tacaacgaat
     6661 ggtaggacaa aacaaggggc ggaaaaactt ttttgatcat ttcataaaaa actttttcct
     6721 acagcattcc cttgttttct cttaccacac gttgtgacct aaaagcacgc cgacgaacgc
     6781 ttagctatac gaaaatgacc aaccaaaaca aaaaagtgag gtgaatggaa acaaaaagaa
     6841 attgaaatct cccaaaaggt cacccgcctc ggagacaact tgctgccgaa aatggttggt
     6901 tgattcggct aagtatcaaa taaggcaaat caaatattat tggaggaata gatcatgaaa
     6961 gcaaatacac catacaaagt aggagacatt ttttatagta gttggggcta tgaacaaacc
     7021 aacgttactt tttggcaaat tattaaatta accaaaaaaa cagcatggtt tcgacccatc
     7081 aaaaagcaaa ctgtaaaaaa ctatacttct atgagtggag aaactatgcc aataccaaat
     7141 gaatttatcg attatccgct tgcacgaacc aaagacagca ttgttagaaa acgaattaat
     7201 ccagccttat atcccaatga attatacggt aatcgcagtt gggatacatt ttaccgctat
     7261 gataatcaac cggtttatga aagcagttat tactaagagg gtatttccct cttagtcaac
     7321 gttacaaaaa taaaaggagc aagaacaatg aaaccaataa ctctatatga aatcttaggt
     7381 gaagaacggt ctgacaattt accaacaacg cataaattaa gagttcttgc ttctaaatct
     7441 atcggtaaaa aatgataact gagtatttct aatcaaggag agattgcaat gctaagaaca
     7501 aatgctattc ctatcgttga ttcttacgat cggaatacca ataactattt aggatctttt
     7561 gaacaaacag atgaaaatat tttgaactat gttgctgggt taagtccttt tgaatctgta
     7621 cgtttagttg aacatacaac agatacactc attttaacaa caatcggcta cttcttcgat
     7681 caggtatctg accaacaatg gttacaacag attttaccta aacttatcgc aaaacaaact
     7741 ggaaaaagca ccatcgaagc agtcaaaata tttttttact aaatacatgt attcattctc
     7801 aagggatttt ttcccttgag tgaaaggaga aagaatgatg tccatacttc aaccctttgg
     7861 tgaaccaatc gaacgaacag aattcattca acactatatg aaattatttg ttcaagttat
     7921 taaacacact catcaaattg atgaatttta ttccaaagaa atagagtatc ttctagcaga
     7981 aaagcaaaaa attgctttac tttatgacta ttttgtcgaa atgtatgatc gcgcaccaga
     8041 ttacttttat ttatctgata cacttactac taacttttta gctaaagaac atctttttgc
     8101 ctcacacaca aaaaacctta tgtgtgtaga acactttgtc aatacctatc ttcatctgtt
     8161 aaaaattcaa aaaatctgta catttgaagc atttcaaaca gattatctat ttattttaga
     8221 tcgtgaagca tatcatgcaa aactagcatt tgaaaagcaa aatcaagcca ttgaaggcta
     8281 tccagaatta cgcatccaaa acaattcttt tttacaacaa cgattgttga aacagctaat
     8341 aaatggattc catcaacgaa ataaagccta tcaaaaagat caataactgg ttctttttga
     8401 taggtttttt ccatcaaaaa cagaaacttc tttttttaat tgtttgatta cttttttagt
     8461 cataaagatc attcaaattt ttttaaataa attatccata tcttctaata ttaatggaac
     8521 atctgcaatt attcgatccc tat
//
LOCUS       DAXLPC010000104         8327 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.105, whole genome shotgun sequence.
ACCESSION   DAXLPC010000104 DAXLPC010000000
VERSION     DAXLPC010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8327
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.105"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..2196
                     /locus_tag="ACF3UE_002401"
     CDS             <1..2196
                     /locus_tag="ACF3UE_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HFD3635767.1"
                     /translation="VANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPG
                     GFDGVYTPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRK
                     MQQWLNVNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTY
                     PVSEGNSGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIAD
                     VVVIKGLLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDER
                     NKYLTTEELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTT
                     VIYFAVDLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFA
                     FVSDMSTGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSND
                     TNNDNYIAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPV
                     TEHDRKIYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVS
                     DFAGWLGDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAK
                     RNSDSTALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVG
                     IISFFIDKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            2276..2671
                     /locus_tag="ACF3UE_002402"
     CDS             2276..2671
                     /locus_tag="ACF3UE_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635768.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            2996..3613
                     /locus_tag="ACF3UE_002403"
     CDS             2996..3613
                     /locus_tag="ACF3UE_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3635769.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            3654..3953
                     /locus_tag="ACF3UE_002404"
     CDS             3654..3953
                     /locus_tag="ACF3UE_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HFD3635770.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            3987..4154
                     /locus_tag="ACF3UE_002405"
     CDS             3987..4154
                     /locus_tag="ACF3UE_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD3635771.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(4199..4804)
                     /locus_tag="ACF3UE_002406"
     CDS             complement(4199..4804)
                     /locus_tag="ACF3UE_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3635772.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            4929..7916
                     /locus_tag="ACF3UE_002407"
     CDS             4929..7916
                     /locus_tag="ACF3UE_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HFD3635773.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTK
                     LIKSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITT
                     FSRFVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLA
                     DDSHKEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKK
                     LALLVAFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSD
                     IVDLVMSSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYR
                     KFRKFIPDILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYY
                     IHEYPEQTNKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLL
                     EQLDLPSSANEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKE
                     DKSFRRRIQQLLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSE
                     SCNIGFSPVSKEGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDG
                     HMASADGIRYITPQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSL
                     YLLEGFLNQPSELTPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDAN
                     AHYGELDTLSQNSINMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGK
                     AITEYGKVYKTKHQLRYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYD
                     GMEEQLNALGLVTNAIIYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVG
                     KYTFRYEAELSNGKLRPLNVEEF"
     gene            8065..8274
                     /locus_tag="ACF3UE_002408"
                     /pseudo
     CDS             8065..8274
                     /locus_tag="ACF3UE_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346508.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
BASE COUNT         2827 a         1284 c         1570 g         2646 t
ORIGIN      
        1 gtagctaatt ttggacctac cactgaaaaa atgtacgata atcaggttac tcctaaatgg
       61 ggcaaaaatc tacctaaaaa tattgtattt cttattcaag gtgccttttg gtgtaagggg
      121 attaatccag gtggcttcga tggggtatat actccatatt tagatactgc tgtaaaagag
      181 ttgcagactg atgcagggtt taatggaagc gctgtaactg gagttttgga tgcgaaatgg
      241 gccaaagcgt tatttgatat gagtgctttt gttcttgttc ccggcggaga tagtaaaatt
      301 agaaaaatgc agcaatggtt aaatgtaaat tatttagaat acacgggaat aatgccttgt
      361 gatggtattt atcaaagaaa ttcaaatcaa gcattaattt ttgcattaca agctgaacta
      421 ggatattctc ccagtgaagc aacagggtct tatggtaatg ggacaactag taaaacttat
      481 cctgtgtctg aaggtaactc gggaaactat gtaagaataa ttcaatatgg attatatgtt
      541 aatggttatt ttgaagacgg tacattcgat ggtattttca ctaaatatat gggtttagaa
      601 gtactggcat tccgaaaatt tatggtattg cctgaatata ctgaaatagc agatgttgtt
      661 gtaataaaag gactattgtc tagcgctgga gatattagaa gatctgcaga tggcgcagat
      721 acttctacgc aattaactag atctcaaatc caaacattgg ttgataatga tataaaaata
      781 gttggtagat atcttactgg tactgttgga attggaaaag atgaacgaaa taagtatcta
      841 actacagagg aattgaataa tattttttct aaaaatttat ctgtgtttcc tatctatcaa
      901 gatggaggtg cagcattagc ttattttact tatgatcgtg gcttatcaga tggtaagaag
      961 gctatagatg cagcaaaaaa tctaaatata ccattaacaa cagttattta ttttgctgtt
     1021 gatctagaca tgttagggga agaaattctt gcatatgctg gagaatattt taagggggta
     1081 tctgctgtaa tgtcatatag cgggtatcaa acgggtgttt acggaacaag aaatgtttgt
     1141 tctcaaataa tcaataacgg gtatgcttcg tttgcatttg tttcagatat gtcgactggt
     1201 tatagtggga atttaggttt tcctatgcct agacaatggt cttttgatca atttgttgaa
     1261 tttaccatag gaagtggcaa cggagctgtt ggtatcgatt taatcgctac atcgggtaga
     1321 gatagcggat ttaatgagtt atcaaatgat actaataatg ataattacat tgccaaatac
     1381 aatcagaagg ttataaatca gatggtacgt gcgtatcaat atctatcaca agctggtctt
     1441 gataatcctt ggaaccctca tttgacattt tatagatatg taaattattc tggtttgtca
     1501 tgggacatca tttcttctcc tgtaacagag catgatagaa aaatttatga tgaatatagg
     1561 aataaattaa ctaatagcga gggcctgtat aattatttta tagatcctaa tactggttca
     1621 ataataggtt tgcctcactt aattgtgacg ttacaatcac agatgtttct agccgacaca
     1681 atcaatgata gtgtttctga ctttgcaggt tggttaggag atttaatgac ttgctggggt
     1741 gaagttaaga aattaggaat acaaatggag caaggtgtat ttgcattagt aggtacggct
     1801 gcaggtggaa catttagtct agaagattta taccaagatg ttgacgcggt aaatgtttat
     1861 accttagcaa aaagaaattc tgattcaaca gctttatcgg ctttaaaaac gtactattgt
     1921 gataagggtg ctattgatag atttaatcaa tttgttaaga acagatttgg ttcttcagat
     1981 aaaatcgctt cagtaacaaa tagtttatta gaaaatgacg aaacagttga tatcttaggt
     2041 gtagggataa tttcattttt cattgataaa atagttaata attcacttgg gacagatttt
     2101 acttatcttg attttattgg agatgagggg aaagttgcaa atggattttc tgaaaaaatt
     2161 attcaatttc aagaaaatag aagtaaactt aattaagaat cgtttactat ttaaacagtg
     2221 tccttttcct ttttaaatat atacgataaa ataagtatat gaattgtaaa aggacatgat
     2281 gattatggaa gaaatagaat ggaataatct gactcaaaat aataaaaata attctggatg
     2341 tggaattatc tttatgtttg ttatagtttt gggaatagta gtacttttaa taactgtcaa
     2401 gatagtagat tactttgcga atactcctga agaacaaata cagagaaaac ttcctgagtt
     2461 tgaaagagta ccaccttatg atccaagaga taattcattt caagtaaaaa aattaaaaga
     2521 gtctccaaat gaaatgtggt ttgaagttac agttgaatca agcgacttca aagaaaaaaa
     2581 gaaagaatac aattatattg taaaggcaaa agtatcaaaa agatttattt ttaaccctaa
     2641 attagaaata tatagtgttg taatagaata atagtgttaa aaaaattgta aaagttaaag
     2701 aagtcaaatt ctgatgtgaa aaataaaata taccatggaa gacataaaag aaaaactgga
     2761 taactagttt atttaatggc agaccgttaa ggcctgccat ttttatgtat tttagcggaa
     2821 taaatataat catgcgggag tgtaaactta ctgtttcaaa aagtatactt tttgacatgc
     2881 cttgattttc tttgtttatg tatggcataa taaccacata atacaatttg aaacgtttct
     2941 gatttaatct gattgttttg aaacaatttt agtgaaaaaa gggtagataa aaacgatgag
     3001 aaaatttttt tatatccggg tcagtagtta tgatcaatcg atcgaacgac aactgatttc
     3061 cgcgaaggaa ttaggaatcc ctgaagaata tatatttgta gaaaaagcca gcggcaaaga
     3121 ttttaaacgc cctgaatatc aattaatgaa acggatgttt cgaaaaggag atttactcta
     3181 tctacaatca ttagatagac taggcagaaa taaacaaatg attttagaag aatggcgaga
     3241 attaactaag gaaaagcaga ttgatatttc tgtgttagac atgcctctgt tagatactgc
     3301 tagttacaag caactagatg ggttagagac gcttatctct gacttaattc tgcaattact
     3361 cagctatatg gccgaagacg agcggaaacg aattaatagc cggcaaagag aaggcgtaga
     3421 agctgcgaaa caaaagggtg taaaattcgg cagaaagaaa attgctttac ctcctgaatt
     3481 tcctgcgatc tattctgact ggaaagcagg aaagataact gcagtctatg ctatggatca
     3541 attgggcatg aaacgaaata ccttttatcg acgggtgaaa gaatatgaac ataccttgca
     3601 ccacttttct tgatagatat aacagctatt agacgggaag ggagagtttg aaaatggact
     3661 taacgaatca aagggtcgtt tttactggaa cgctgcagca aatgacacga acccaagcca
     3721 tcggtttggt tcactcttta aacggccatt gtcaatcaag tgttacttca aaaacaaatt
     3781 tcctggtttg tggtcagtat tctaagtcgt tgtttgatga ttctctctat acaaaaaagg
     3841 aacaaaccgc gcgggacttg attgcgttag gtcatgagat taccatttta tcagaagtcg
     3901 aattttatgc gttaattagt caacagttga aagaatggca acggtattta taatcgttag
     3961 taaaatttac aaggaggaaa atttttatga agcgaaaatc ttatgatcgt tggggcattg
     4021 aaataactag ttttaatcga aatattgctt ttcacgtgga gtgtgactgt ggggaattag
     4081 caaaaagtgt ttatcaaaaa aattactttt actgtcctaa atgccatcgc cgatacgggg
     4141 tacatggaac atagaaacga aatagtgcgg tagaaaagcg aatgaatgta gtatatttct
     4201 acaaatcatt cgctttcttt attttataaa tagttggtcg agagatcccg ttttcttttg
     4261 caatctctgc aactggaatg ccttgcttta acatgtccac cacggtttta aaaactaagc
     4321 gtttttgcgg atctgttgag ttaatagaat actcgattgg tcgtccctta tatcggccgg
     4381 ctttttgagc caataatact ccttgccgct gacgttcacg aattttctca cgctcgtttt
     4441 gtgcaatata acttagcagt gataaaaaca tatcgaacat agcggtatcc aggagttcat
     4501 ttccagtatt aaaatctaaa aactgtgcat ctaatatttt taacgctact tttttctgtt
     4561 tcataaaagc aactgtattt tttatatctt cataatctct tcctaaacga tctagtgatg
     4621 taacgatgac gcaatcacct tcacggatat aatttagtaa tttttgaaac tcaggacgct
     4681 cagtatcttt accactggct ttttcttgga ataatttatc aatgttaagt ccttccatca
     4741 ttgccaattg tcgatccaaa ttttgatctt gtgaagatac tcgaatatag ccaatttttc
     4801 ccataaaaaa ctccttttta aaagtgatat aatttacatg taaaatttac ttgtagtttt
     4861 actgctatca tagcattttt aaaaataaat tttatgtaga cttaaaattt acttcatgga
     4921 gggtttaaat ggatgaaatc aaaagtaaca aaaaagcatt tggcatttat ttaggagaac
     4981 ctagtacaga acaattaaac caattttttt atttgcatga aaaagattta gaattgatgg
     5041 agactatacg acgaccagct actagattag gttttgcact acagttagtc tcactacgtt
     5101 ttttaggaac ttttatatta gatcttacca atattcccca aaatgtattg agttatgtag
     5161 caactcaact aaatattgat cctggagaaa ttatctacta tagcaggaga cagaccaggt
     5221 atcagcacac aaaattgata aaatcacatt atggatatca agatttcaac caaccggaaa
     5281 tagaaacata cctagctaac tggcttttaa atagagcgct gtatacaaca gaatcttcag
     5341 atatgttgtt tgatatgctt ctaaaaaaat gtctggatga aaagattgtt ttacctggaa
     5401 ttactacttt ttctcgtttt gttgctagtg caattgaaaa agctgaagag catttatacc
     5461 gacaattgtc tttggttcca actgaagatg agagaaagcg gcttctcaat catttagaat
     5521 taattggaac tccagtttat ggggcaataa tcaaaatgga cattttgaga accccgttag
     5581 ctgacgatag tcataaagaa atagccagag gttttgaccg actaaagcaa tttcaagctt
     5641 tctctactga aaaatggaag atggaatcta ttcctgaagg gaaaataaaa gttcttgcaa
     5701 attatgcatt taaagctaaa gctcaattaa ttcaacgaat gagtgaacag aaaaaactgg
     5761 cgttgttagt ggcatttatt ttcatataca aacgtaaggc tatggatgaa caaattttag
     5821 cactatctaa tttttttgaa actgttttta gacgcgccaa aaataaggaa tctaaagaac
     5881 gtcttcgtac cataaaagat ctagatcgag ccgcatcgac actttcagat attgtagatt
     5941 tagtaatgtc cagtcattct gatactaatg aactatccct tcgcgatcgt atcttagaaa
     6001 aatattctga ggaaaatgtt accgaagctg tatcgcaagt tcggctattg gttaaaaatg
     6061 atcgtgaacc aatagccatt tctgaacttc tgaacactta tcgaaagttc agaaaattta
     6121 ttccggatat tttaactaca ctaacatttg acagcaatga ctacggtaac aactgtaagg
     6181 aactctggac cttcattaat aatagatttc ctaagccgat tacttacaaa atgtttggag
     6241 ctattaaaca tactcttcca aagaaatgga tttattacat tcatgaatac cctgaacaaa
     6301 ctaataaatg tgtattgatt gcagctgtcg aattgttaat tcaatcttta aaacgccatg
     6361 atatttatat tcctcagagt gtcttatata acaatcctat ggattgcttg attgatgaga
     6421 aaacttgggt tcaacaaaaa tacgttttat tagaacaact agatcttcct tcttcagcaa
     6481 atgaaatgtc tttatggtta aagaacgatt tggaactgtc ttataaagaa gcgctaaatc
     6541 gttggcctac ttctaaaatg gccagaatag aaaatgcaga tcgcctggtt gtctctagac
     6601 ttaaaaagac atatgaaaaa aaggaagata agtcttttag acgtcgcatt cagcagttac
     6661 ttcctaaaat tgatttgtca gatttgttat tggaagtaaa ccaacagtta aatcttactc
     6721 aatcatttaa ccacttaagt gacaaggaca ccaaaatgaa agacttggat attagtttat
     6781 tagcagttct tttatcagag tcctgcaata ttggtttttc cccggtttca aaagaaggat
     6841 ttgattcttt aaagtatgat cgtcttgtct atgtcaatca tcattatatt cgagtggata
     6901 cactttcagg agctaatcaa aaaataatac atgcacacag gaaacttgcc acctctaaga
     6961 tatggggtga tgggcatatg gcttcagctg acggtattcg ttatatcaca ccacaacgtt
     7021 ccctatattc tagaagtaat ccaaaatatt ttggccgtgg tcgtgggatc acattctaca
     7081 attttgtctc tgatcaatat atagggttcc acggaatggt cgtttcaggg acactgcgag
     7141 attcgcttta ccttctagaa ggattcctca atcaacccag cgaattaact cctaatcaga
     7201 tcatgactga tacagctggt tatagcgata tgatttttgg tctctttggc ttattagggt
     7261 ttcaatttag tccaagaatt gccaatgata aaggaaccaa actttggcga atcgacgcta
     7321 acgctcacta cggggaactt gatacgttgt ctcaaaattc aattaatatg gaactgattt
     7381 atacccattg ggaggacatt cttagggttg caggttcgtt gaaatctgga aaagtgaatg
     7441 caacagaatt aacgaaatct cttcaacgga atgggcaacc cacgccttta ggaaaagcaa
     7501 taactgagta tggaaaagtt tataagacga aacatcagct tcgttatatt tctgacgaaa
     7561 tatatgcacg gcaaatttta gaacaattga ataaggggga agctcggcat gccttatgcc
     7621 gtaatatttt ttatggacga aaaggaaaac tctaccagac ttattatgat gggatggaag
     7681 agcagctcaa tgcattagga ttagttacta atgccatcat atattggaac tcactgtatt
     7741 tagaaaaagt atttgaacaa atgaaagctg aaggattcga ctgttccgaa gaaatgatac
     7801 gcaggcaatc tccactaatt agtgatcaca tcaattttgt tggtaagtat acgtttagat
     7861 acgaagctga attatccaac ggtaagttac gtccattgaa tgtagaagaa ttctagcaat
     7921 gttcgggttt tgcatgctac cgcactattt cgtatgactg ttccagcgaa tcacttcgaa
     7981 tagaaaaaga gaaaaacacg agaacagcgt taaatcaacg tttcttgtgt ttttactttt
     8041 gtgctaccgc actatttcgt ttctatgttc catgtacccc tttatcaaga agcgcaaaca
     8101 cgccaaattg ccgattggtt gatcggcatg aacgcaagcc ctttatatac cttgaattta
     8161 caacaaaaag gcgtacaagg tacattttca ttaggacgtg tacaaacacc gactttatat
     8221 ctcatttatc aacgccagga agcaatagaa aactttaaaa aagaaccttt tttcctgaat
     8281 aattcatagt tttactaata gtctttccta acattgattt aatagtc
//
LOCUS       DAXLPC010000105         8292 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.106, whole genome shotgun sequence.
ACCESSION   DAXLPC010000105 DAXLPC010000000
VERSION     DAXLPC010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.106"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            674..1900
                     /locus_tag="ACF3UE_002409"
     CDS             674..1900
                     /locus_tag="ACF3UE_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3635774.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFKEITGISSEKFQKTFPTRQLAIKA
                     ENEMKKKIAKVLREENANSLELKGQIKFKEFYKSKWLPRYELGQTTRSHKAPSDITII
                     NTKNLFRLHILPIFGEYAMSYLNANTEIISDELTKKSKEYANIKIIKCYVRSMFDIAE
                     VLNYIEFNRTTKIIQSITAPKKVALEEKRIREGKQALSSKELTDWLDAVRDDFNDQLL
                     SFHDYTLFMLTLYLGDRKSETYALQWKYIDFENQTVRLKYALDKHTKKKFTKGRKDTI
                     IQVPEIVMTLLQEWKSVQAEQLLKLKIKQTPDQYLFSYSKPSGEVNCPVHTDYLNYRI
                     NSIKKRHPHLVHLTPHKLRHTYATLARQGGADMNQISNALTHSGISTTKIYVNTPDLV
                     DKAVFEAFQRGLQKSN"
     gene            complement(2058..2675)
                     /locus_tag="ACF3UE_002410"
     CDS             complement(2058..2675)
                     /locus_tag="ACF3UE_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3635775.1"
                     /translation="MAKIGYARVSSLDQNLDRQLELLSECDKIFSDKASGKDTNREGF
                     QEMMKFIREGDIVVVTELKRLGRNNKELTETMNLIQLKKATLEVLNLPALTGITDDNL
                     RRLLNNLIIELYKYQAEEERRYIRETQQQGIALAKAKGKYKGGTLKYRENDPRLQLAF
                     NLFLTGSTDKEVEELTGINRRTFRRYRMKHGITNEVREQKNKSFS"
     gene            complement(3358..4353)
                     /locus_tag="ACF3UE_002411"
     CDS             complement(3358..4353)
                     /locus_tag="ACF3UE_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3635776.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKNN"
     gene            complement(4448..5320)
                     /locus_tag="ACF3UE_002412"
     CDS             complement(4448..5320)
                     /locus_tag="ACF3UE_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3635777.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNKLLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            complement(5333..6760)
                     /locus_tag="ACF3UE_002413"
     CDS             complement(5333..6760)
                     /locus_tag="ACF3UE_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HFD3635778.1"
                     /translation="MTKRAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPGDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDRLYMKPVRELEQLRVG
                     SGVETTVNLAGEIIIAQDASFKEALIDVLLTKSKNQEVKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            complement(6814..8088)
                     /locus_tag="ACF3UE_002414"
     CDS             complement(6814..8088)
                     /locus_tag="ACF3UE_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3635779.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLGVTIMCVRIGLCGFASTPLSVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGILRDNVGYQPTFK
                     IISLIVLLAGIYAFFILKQDDRDVQGDPFIRG"
BASE COUNT         2746 a         1524 c         1185 g         2837 t
ORIGIN      
        1 attttaaatt tttacatacc tgtttatgaa aaactaaata atctgtcaaa aaaatatgat
       61 tgttcatttc taaatatgtt ttccaatttt aaaatctttt ttagcatttt tgtttccttt
      121 tcatatggtt tttcgttgtt aatagtgact aggatgatat tcctattttg accattgaca
      181 attaaatata atttttgaat aacgttccct gctattcgag ctaagaattc aagtacgcca
      241 tgacctattt agcgataact acttagagat ttctttttgt tttgggaaga caaaatgcca
      301 tgacaatagc agtagataat gatacttccg taaggctcgc cgtaaactgg ggagaggtga
      361 aattcctatg tgcttaccca agtcaattca aaaattttag ttcatttata aggggatgat
      421 tttattaaat caatagtcta tctaaacaaa aaacaaacct gtgagttttt aggaattgat
      481 aacaatactt tagataaatg gattcgtata tataattttc ccgtaataaa aatagacggt
      541 ataattcgct ttgatgtaga agatatcaaa ggctttatgg atacgttcaa aaagatttga
      601 attttacttt tgactgcata tactaaaagt agcgaaatat actgccttac ttttttatta
      661 aggagtgagg aagttgccta cgaagctttc aaatggaaaa tataaaacta atttgagata
      721 tccaaaaaaa tttaaagaaa ttacaggtat cagttcagaa aaattccaaa aaacatttcc
      781 aactaggcaa ttggctatta aagccgaaaa tgaaatgaaa aagaaaatcg caaaagtctt
      841 aagagaggag aatgcaaatt cattagagct caaaggtcaa ataaaattca aggagtttta
      901 taaatctaaa tggcttccta gatatgagtt agggcaaact actagatccc ataaagctcc
      961 aagcgatata accatcatta atacaaagaa tttatttcga ttgcatattc tgcctatatt
     1021 tggtgagtat gccatgagct atcttaatgc aaataccgaa ataatatcag atgaactcac
     1081 aaaaaagtcg aaggaatatg caaacataaa aatcattaaa tgctatgttc gttccatgtt
     1141 tgatattgca gaggttctaa attatattga atttaatcgt acaacaaaaa taattcaaag
     1201 tattactgca cctaagaaag ttgctctgga agaaaaaaga atacgagaag gaaaacaagc
     1261 tttatcttcg aaagaactca ctgattggtt agacgctgta agagatgatt tcaatgatca
     1321 attactttcc tttcacgatt acactctttt tatgcttact ttatatcttg gggatagaaa
     1381 gagtgagacc tatgctttgc aatggaaata cattgatttt gaaaaccaaa cagtccgtct
     1441 taaatatgcc ttggataaac acacaaaaaa gaaatttaca aaaggtcgaa aagatactat
     1501 tatccaagtt ccggaaattg taatgacact attgcaagaa tggaaatcag tgcaagctga
     1561 acaactattg aagttgaaaa ttaaacagac acctgaccaa tatcttttta gttactccaa
     1621 accttctggt gaagtaaatt gtccagtcca tactgattac ttaaattatc gaattaattc
     1681 tataaaaaaa agacatcccc atttggttca tttaactcct cataaacttc gacatactta
     1741 cgcaacttta gctagacaag gtggggctga tatgaatcaa atttctaacg ctttgacaca
     1801 ttcaggtatt tcaactacaa aaatttatgt gaatacacct gatttagttg ataaagctgt
     1861 gttcgaagcg tttcagcgag gattacaaaa atctaattaa tgtgttctag aatgtgttct
     1921 aaatataaaa aaaagacact ttccaaataa ttggaaagcg tcttgaacgt tgatatataa
     1981 aggatattaa cgttttgaga attgagatgc tttacgagct ttcttaagac ctggtttctt
     2041 gcaaaattat attagcctca actgaaagat ttattttttt gctccctaac ttcattagta
     2101 ataccatgtt tcattcgata tcttctaaac gttctacgat taatccctgt tagctcttca
     2161 acttctttat ctgtagatcc agtcaaaaac aaattaaatg ctaattgaag tcgcggatca
     2221 ttctcacgat attttagcgt acctcccttg tatttccctt ttgctttagc gagtgcaatt
     2281 ccttgttgtt gcgtttcgcg aatataccga cgttcttctt cggcctggta cttgtatagt
     2341 tcgataatta agttattaag taatcgacgt aaattatcat cagtgatacc tgttaacgct
     2401 ggcaaattca aaacttccag tgtagctttc ttcagctgaa ttaaattcat cgtttctgtt
     2461 agctctttat tatttcgtcc aagtcgtttt aattctgtca caacgacaat atcaccttca
     2521 cgtatgaatt tcatcatttc ttgaaatcct tctcgattgg tatctttccc acttgcttta
     2581 tcactaaaaa ttttatcaca ctctgataat aattctaatt gtcggtctaa attttgatct
     2641 aagctgctta ctcgagcata cccaattttc gccataataa aactccttta aaattctgaa
     2701 atccggatca tttttaaatt ctgttgccca actctgttgt catttttcta gataaatggc
     2761 ataaattttc agcgctaagt gacaaaagca actaattttt catgatagat ttttaaatat
     2821 ctcaatctat ctccaaaatt agttgctttt gtagctatag ttgactatga atatgacaaa
     2881 taattagaaa aaactgtgcc aattaaatat aaaaatgaca ctcatttaca ttcaatagaa
     2941 caccaagagc ccaacagggt atactctggt gtccttttaa aaaagtaact ttctgaccta
     3001 attaattgag ctactaaaaa agctatgaaa tgaggaataa aaaagggatc aaaaactttt
     3061 aagtttctga cccttttgag ttctaattat ttcttccaga acgaagaatg ttatctgctt
     3121 tatctgcaat tgattctgtt agaaggactg aaaaatttat gccagccctt ttgcctagct
     3181 tatccgccca ttgaggaatt gttaaggttt ttctgacaag ttctatgtct ttcaaatatt
     3241 tggcaacatc tacacagatt aaaagcatga ttttgtatca tagtctatta taagagattt
     3301 aacaattttt tatatcacga attaataatg aaattatcat tgatagtctt tataaattta
     3361 attgttcttt ttctttactg atgtcttccc catccataat gtgacaggta aaatatattc
     3421 cttttttgtt tcttctttat ttattcgttt catcaaaata gcaacagctg tgtctgctat
     3481 atcattaatt ggttgtatta ctgttgtcag atctggtaat atactccgag tcattaaagt
     3541 accatcatat ccgactacta ataaatcagc tggtacattt aacccctttt cttttgctac
     3601 ttgtaatatt agggccgcat cgatgtcatt tgaagcaaaa ataccatcta ttttaggata
     3661 atcctcaaac atttggaaaa aaatctgttt tttctttaca taagaaatat tgaaatctaa
     3721 tgtcacagtt cgtggaatta actgatatgc tttcatagta tcttcatagg ctagtctccg
     3781 acgattagcc ggagtctgta agtcaattgg accgtttgta tgaataatat tttttgcacc
     3841 ttgtgcaatt aataacttgg ttgcaagttt tccaccattg tagttatcgg attcaacaac
     3901 tggaatatct tcattcatca ctcgatcaat tgcaacaatc ggtaaattct gatatttata
     3961 ttcctgaatt ccttggttat gtgtaccaac aattaaacca tctacttgat cagacaataa
     4021 ctgatttaaa taatttgttt ccttttcttt attattcatc gaattgccta ttaatacctt
     4081 ataaccaatt tcatataact ttttttccaa tgcctcaacg agttcactaa aaaaaggatt
     4141 ggctactgta ggaaatagta acccgacaat gttagttttc ttttgaaata attgacgcgc
     4201 tacaacgttc ggttgataat tgagttcttc tatagcctta taaacattat caatcgtttt
     4261 ttgacttaaa tagccacgat tgtttaatac acgtgaaaca gttgtttttg atacatttgc
     4321 tcttttggca acatcttcta attttgggcg cattctcttg tctctcctaa ataatgcaat
     4381 aattaactat cgaaaaaaag aactctatag aactactata cctgataatc gatatttttt
     4441 ctatgtttta ttcttgtaat tgattcaagc ccaaagcaaa gtttcctagt gttgccgatc
     4501 cattattttt aattaaagga cgcgtaatat atttacttaa cggtggtatt tccacgtaat
     4561 catccaataa tttattaaca ttaacacgaa ttttttctaa caatttttca tttactacgc
     4621 ttccaccaaa tactatttta tccggtcgta taatcaatgt tgtttgaatc acagcttgtg
     4681 ctagataata ggccattaca tcccaaatag gatccgttaa agaaacgtct tcaccctttt
     4741 ttccaaaacg tgcttcaaac gttggtcccg caactaagcc ttctaaacaa tcaccatgat
     4801 aaggacaaat tcctttaaaa tcaatatcat caggatggcg ttttacaaac gtatggccca
     4861 tttctgaatg accaaacgat cctaatagtt ttccgtcaac aacagctcca ccaccaacgc
     4921 cagtaccaac ggtgtaataa actaatgaat ttattttttc attcgataaa gtggacatga
     4981 tgtactctcc ataagctgat ccgttcacat ccgttgtcca agacattgga acattcagct
     5041 catcttgtaa ataacctaac acattaacat ttcgccatcc cacctttggt gtagacgtaa
     5101 tatatcctga ttttggtgaa ttttttcgaa tttctattgg accaaatgat gcaataccta
     5161 atgcatttat atcaaactgt ttaaaatagt caacagtttt tttcaatgtt tccctggggg
     5221 tggtcgttgg acaaattatt tggtcttgta ctcggtaatc ctcgtctccc acggcacata
     5281 caaatttagt cccacctgct tctatgctac caattaacat cataaaacct ccttactcgt
     5341 aagaaattgc atcttttttt agatgataaa ttgtactcga gacaaaagct tcttcactaa
     5401 cactcaaatg catacttggt tgattttctg tataataacg ctctgtaaaa acaagctcgc
     5461 catcattaat aaaaatctct gccgaacttt tatcgataaa cactcgaagt gataatctat
     5521 cacacatctg aatggttcca taccttggat catttttgcc gttacgagtt aaggtacatt
     5581 catttttatc cttagaataa aaaatattga ttaactcttc atcttttgtt tttaatgaaa
     5641 atttgacttc ttgatttttt gatttagtca atagtacatc aattagagct tctttgaatg
     5701 aagcatcttg agcgattatt atttctcctg ccaaattaac tgtcgtttca acgccgctgc
     5761 caactcgaag ttgttctaat tctctcacag gtttcatata caaacgatct ccaattaact
     5821 ctaattctcg aggaagcgtt aatgctcctg cccatccgtc tactttttca ggcatagggc
     5881 tttcccacat atccatccag gccataacaa tacgtctacc atctggagat aaagttgttt
     5941 gtgttgcata gaaatcgtgt cccttatcta attcataaaa atttcctcta atgaattttg
     6001 ctgtctcata atcataatca ccgataaagt agcctgtttc atatagattt aaataatctt
     6061 ttccatttgc ttcaattccc tgaggggata ataaaagaat agattttcca tttaattcaa
     6121 aaaagtctgg gcattcccac ataaatcctt ctgtaagtac ttccttcgct ttagaaattg
     6181 gtccaatgta atcccaattt aataaatcta acgactgata aacaatagca cgacctaatc
     6241 catctttttc ttgactaccc aaaaccatgt aatatttttc atcgtgtttc catacttttg
     6301 gatctctgaa atgatgtgtg ttatcttctg gtgcttttgc tattacagga tttttttcat
     6361 atttagtaaa gtgaatgcca tccgtactat acgccatgtt ttgattttgc caaaaatgat
     6421 ctggatcatt gtctccataa tagtgatgtc ctgtatagaa cagatacaac acaccatttt
     6481 tttcaatagc gcttcctgaa aaacaaccac cttcatcttc ttgatctcca ggagtcaaag
     6541 caagtggtaa agattcccaa tgaactaaat ccttacttct agcatgtgcc cagtgcattg
     6601 gtccccattc agcactatat ggatgatgtt gataaaacac atgataatac ccatcaaaat
     6661 agcaaaatcc atttggatca ttaatccatc ctgatggtgc agacacatga tatcccaaac
     6721 gataacgtgt atttgttaat tctatagctc tttttgtcat aatatattcg ctcactttct
     6781 agataaaatt gttttttatt ctgttggttt ccattatcct cgaataaatg gatccccttg
     6841 aacatctcta tcatcttgtt taagaataaa gaatgcatat atgcctgcta gtaatacaat
     6901 aagagaaata attttaaatg ttggttgata gccaacgttg tctcttaata ttcccaatgg
     6961 tgttgataaa atcacttgcc caatttgagc agctatctga aatcctatca tatagagggt
     7021 tgctgatagc tttgtatcaa aatgaagtgt aaaatagcga aacattggta atgtaaataa
     7081 tggtacttct aaagcatgca acatttttat gcatgaaaca gataatggtg tcgaggcaaa
     7141 cccgcacaat ccaattcgta cacacataat ggttacacct aataacaaag tatttcgaac
     7201 ccctaatttt ctcataatga ttggaacaat tcccatcatt aacgcttcac aaaatacttg
     7261 aatagcattc aatgtcccat atattttttc accattagct gatgttgaaa acaaaccagt
     7321 ataaaatccc ggaaacattt gttgatcgaa taccgtataa aatgtccatg taaaaacaat
     7381 aaagatgatt atcgtccata attgaggcag tttcattaga tcaaacattt cttttaaaga
     7441 aggaatacta tttgattcag cttgttcttg attaaaattt tgatttgctt cccgttcaac
     7501 tttagggttc caaaataata aatttaacaa tagtaaagaa ccaaagaaag atcccgccca
     7561 aaagtttaaa tgaggatttt ttacaaataa aaatcctgcc aaaagcgcta ccaaggcata
     7621 accaaatgat ccccacgccc ttgcttgtcc atattcaaag ccaaataaac gactaaacct
     7681 ttctgacaca gcttcaaaaa ctcctacaga agctaaatat ccagctgaca aaaatagcgc
     7741 tcccataata atgcctaaat taaaattgtt atctagcaat ggcccatata tccatataaa
     7801 aaatggtcca acaagtgtcg ctaatacaga agcaaaaatt aataaatttc gtttaatata
     7861 caatttatct tgtaatgttc cataaataaa catcaaaatt aaggtaacta acgaatttgc
     7921 cgagaatact gttcctacag cactgccaga taaccctaaa ccatttgatt cagatgttag
     7981 ccaaagttga aaaaatgacc accaaacacc ccaagaagca aaaaatagta ataatgtagc
     8041 tgaactttgt aaataagatt gatttttaaa tacgttaact tttgacatat ttttatcctc
     8101 caacgatata tttgtatccc ctttcatgat aaccggttaa catttttaga aaaggacttg
     8161 tactcctaaa attataaaag aaatccgctt acatgtcaac cggttattct atttggataa
     8221 tgccatataa tgtcacagga tatgactttt attggtgtgt cgcttttctt ttttaatggc
     8281 actatttttt at
//
LOCUS       DAXLPC010000106         7894 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.107, whole genome shotgun sequence.
ACCESSION   DAXLPC010000106 DAXLPC010000000
VERSION     DAXLPC010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.107"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            77..778
                     /locus_tag="ACF3UE_002415"
     CDS             77..778
                     /locus_tag="ACF3UE_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFD3635780.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1387..2403)
                     /gene="tsaD"
                     /locus_tag="ACF3UE_002416"
     CDS             complement(1387..2403)
                     /gene="tsaD"
                     /locus_tag="ACF3UE_002416"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFD3635781.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2400..2864)
                     /gene="rimI"
                     /locus_tag="ACF3UE_002417"
     CDS             complement(2400..2864)
                     /gene="rimI"
                     /locus_tag="ACF3UE_002417"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFD3635782.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2871..3413)
                     /gene="rimI"
                     /locus_tag="ACF3UE_002418"
     CDS             complement(2871..3413)
                     /gene="rimI"
                     /locus_tag="ACF3UE_002418"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFD3635783.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3397..4119)
                     /gene="tsaB"
                     /locus_tag="ACF3UE_002419"
     CDS             complement(3397..4119)
                     /gene="tsaB"
                     /locus_tag="ACF3UE_002419"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFD3635784.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(4310..5290)
                     /locus_tag="ACF3UE_002420"
     CDS             complement(4310..5290)
                     /locus_tag="ACF3UE_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFD3635785.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5314..6798)
                     /gene="galT"
                     /locus_tag="ACF3UE_002421"
     CDS             complement(5314..6798)
                     /gene="galT"
                     /locus_tag="ACF3UE_002421"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFD3635786.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6810..7799)
                     /gene="galE"
                     /locus_tag="ACF3UE_002422"
     CDS             complement(6810..7799)
                     /gene="galE"
                     /locus_tag="ACF3UE_002422"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFD3635787.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
BASE COUNT         2218 a         1698 c         1398 g         2580 t
ORIGIN      
        1 tggtatgtta aaactttaca aattctttaa aaaaagtgac aataaatata gtgaacaata
       61 aggagaggac tttttaatgc gtgttaataa aatcgatttt cacttttcaa aactcagata
      121 tcaacctgat tttgaacatt tctcggatga agagttccaa cagatcaagg aacatactgt
      181 tcttcgttct tataaaaaag gacagatcct tttcgacgat ggtgatccca gacaacggtt
      241 gtatatcttg accaaaggac tcgttcgttt agaacgttat gatgaaagtg caacttatta
      301 ctactatgac tatgtgaata caaataacct ttttcctatg tcaggaatgt ttggagaaga
      361 gacctacact tatacagctc aagcgatgac tgatattgaa acattctacc ttcctgtttc
      421 ctactatgaa aaattagcac gaaaaaatcc cgaacagttg atctatatga tacaaaaaat
      481 ttctaaagta gttgaaatac atgaattgcg tatccaaatc ggattgacct ctagcgcctt
      541 tgaccgggta aaacaaaatt tattcatttt gaaagaagaa ttgggcgtac caacaaaaga
      601 tggtcatatc accattcctt atccgatcac cttaaaagaa ttagcagtga atagcggcac
      661 gacacgtgaa actgctggac aagtaatcaa acaactacgt gattccgggc tgttagatta
      721 tgacaaaaag cgttttactt tctgtaagac agctactact ccagctatga gagaataacg
      781 cgaacaaaaa taagcagtga ccctgataaa tatcagggtc actgcttatt ttcctcccta
      841 aaacttctga aagatccggc agttttagat cactggacaa gactcaaaga ttttctatgt
      901 gtgtttcagt tatgtaatat tcactgtttg caaaaaatac tgttagatta actagatgaa
      961 gcgtcttgtc ctcatccgat ctagattatt cgatattcct cgacaataaa cgattactca
     1021 gtgagggcaa tcagaggaac ggataatgat aaataagctg taaaaaatag caaaataaca
     1081 ataatgatta aaagtatgta aaaaataggg ctttgacaaa aacgtgtcac agccctattt
     1141 cgattaaacg gtgtgtacct gtcaactctt cggtcacaag tcataatgtt cataaacatg
     1201 aggagctgtt ttttgaaatt gttccttgtg aatcagagtt aaacgacagg cttacgaact
     1261 cttgattaaa cggcgttcaa aagcttgcat acgcggtaat aagaacagcc aggtcaaaaa
     1321 catgagaagc cgtttttcct gggctgttct tattacttga tgcagggcag ctttttcaca
     1381 acctctttat tcagataaaa ccaagcttgg atcagcattc aactgatagc tagcaaaatt
     1441 tcttttttgc atttccacat gtgctgctgc tccaatcatt gcagcattat ctccacaaag
     1501 tcgaagaggg ggaatcacta gttctacctc agggagttta gctgccaaag catcctgcaa
     1561 tccttcacgc aacccttgat tggccgctac acctccagct ataatcagtt gcttgactgg
     1621 ataattttga caagctcgaa gtgttttagt aatcaataca tcgatcacac ttgcttgaaa
     1681 gctagctgct aaatcatttt tgtctagatc ttctccacgc tgttgtgcat tatgcaccaa
     1741 attgataaat gcacttttta atccgctaaa actgaaatca taattatctt catggatcat
     1801 cgctcgcgga aaatggtaat tatcttttcc ctgatgagct agctgatcga tttcttttcc
     1861 gcttgggtaa gaaagaccta atactcttcc aactttgtca taagcttctc ctgctgcgtc
     1921 atctcttgtc tccccaatga tttcatatga tccatcttct tgcatataga ctaattctgt
     1981 atgtcctccg ctaacaagaa gtgccatcaa tggaaactgg aatggtttaa ccagacgggc
     2041 tgcatagata tgccctgcca tatggtttac aggaataagc ggcaattggt gtgcccaagc
     2101 aaaagcctta gctgcagaaa taccaatcag caacgagccg acaagtcctg gtccataagt
     2161 gacagcgact gccgataaat cttctgccga cacaccagct tctaccagtg catcttccaa
     2221 gcataaggtg atttgttcta cgtgatggcg gctagctact tcaggtacta cgccaccaaa
     2281 acgtttatga ctgtttattt gagaagcaac gatgttagat aagatctctg ttccatttct
     2341 aacgaccgct acactcgttt catcacaact tgattcaatc gccagaatca attcttcatt
     2401 catttcatcg tctccgtttt taactttctg ctcataatga tcgcatcttc cgtcggattg
     2461 cgataatatg atttccgttt acctaatata cgaaactttt ctgattcata aagttttctt
     2521 gctgcttcat tagatagacg tacttctaaa aaaacatgca gcgaatcttt tatttgttcc
     2581 gtaatcagta attgtaacaa atgccgtgca tgcccttttc cttgttctga aactgcaaca
     2641 gcaatatttg tgatctcgac ttcatctatt actttcgagt atccaataaa gccacagatc
     2701 tggttatctt cagctaaaag cagataatca gagtgaggct gttggatgtc tgccaaaaac
     2761 tgcattttcg tccaaggtga accatgtgga taagcatttt cgctaatcat ccatacgcat
     2821 tctgccaagt acgcttcatc aaaatctttt tttctgcaaa tcaactaatc tcactcattt
     2881 tctaaaagtt ttatcatatc caacgcatct tcttttgttt cagtgtaata tctttttttg
     2941 atcgttgttg cttgaaaccc caatttccga taaagtcttt gtgcatcttg attactcata
     3001 cgcacttcta atgacatcgt ctcacagcga ttcattatag caaagttctc gatttcgtca
     3061 ataagcagcg aaccgattcg tttacgctga tatgccggtc gaacggcaat attcgtgata
     3121 tggcaatcta aaccgaacgc tcttgaaccg ataaaaccaa tcattcttcc attatcaaag
     3181 atacctagat atagatgagg aagcggtgac ttcaattctg atataaaggc actttttgtc
     3241 catggcaatt cgccattata gacttctcgt tcgacatcca gcagctcttt gatatcttct
     3301 gtagtcaatt ctcttagtac gtaacgacga tcgatttgtt cgactgtttt ttctgtataa
     3361 atcattttat cttgaaaaaa gcttctggca tacgctctaa attttttcaa cataactttc
     3421 gtctccaggt gtgtgcgtct ccaaccattt ttcttctgct tctactcgtt ttaaatagcg
     3481 aggaagaaaa gcttgtttct ctgcaactgg ttcaactaaa gcacctaatt gagccacagt
     3541 tacaccactt ggaatatccc atgctggaac tgtattaatc atcgcactag gcaatatttc
     3601 ctttatttca gagaagaatt tgtgacaatc actcccgacg aaataaatag cttcattcag
     3661 cttttgtagt tgtgtgaaca aatcagaagc agaaatatgt acatcttcaa gtacagtttc
     3721 taatctattt tctttccagc ggtatgcccc agcgtataca ttttttcttc gagcatcaaa
     3781 catgggcaca ataatattat ccacaccgat gcaattagcc gcgatggttt tcagactaga
     3841 tactcctact agctctttat ctaatgtata agcaatcgtt tttgctgtcg ttacacctat
     3901 acgaagccct gtataagaac cgggaccatc agaaaccgcg attcggtcaa tgtcttttgg
     3961 acttatttga agatctgcaa acaattggtc gattgcaggc atcagtgtta cactgtggtt
     4021 gcgtttgata tttgtttgta tttgtccaag aatttgttcg tcttctacca caccgatcgc
     4081 caaagtttgg tttgcagtat ctattcctaa tgtaatcata tatttgatcc tttctgctat
     4141 gacattctcg ccttccattg tagcatactt ttttattctg aggatgaaaa taccaaaggc
     4201 aaaactagta caataataca tgattatctg ctggcgggca aattttgccc cttcctgaaa
     4261 cacaaaaaag ctgcggtatc actccatttt cccacagctt ttccatcttt tatttcgttg
     4321 attctcgaat aatcaactct gtttccacaa taatctttct tgaaaccggt gctttggaat
     4381 tacttaattg aagaatcgtc tccactgcta gctctcccat ccattcggta taaactttta
     4441 cagtagaaag cgagggcgtt acatatttcg ctacactgac atcattgaag cccatcacag
     4501 aaatatcttc tggtaccact aaaccttttt cttgaatcgc tttcagtgcg ccaatcgcta
     4561 atgcatcatt agctgcaaaa agcgcatcag gaacatgcgg attcgttttt aaatattgct
     4621 tcactgcttg atatcctgac tcgacagaaa aatctgcttc gataattgga ccttcgtcgt
     4681 agcctttttc tgccaaaact tgttgaaatg ccataattct gggatctttt agccgctgat
     4741 ggtttttctt cgtatattct gttccagcaa gcatagcgat atgttgcgct ttatgggaga
     4801 caaagtgttc aatgactttt tgaacacttg acttaaagtc gacaactaga gagtcgattc
     4861 cttgagaagt gccgtcagaa tctaccaaaa gcaaggcatt ttgggatcct ttcatttcta
     4921 ataactgagc ttcgtcgaat tttcctagtg cgatcgttcc atctgccgga agatcactaa
     4981 tggaatccca cgtttctttc aataaagtaa cgtttgcttc ttctgccttt ttttcgattc
     5041 ctaggcgaat agataaataa taaagatctt caagctcttc cgtatcgtcg taccactgga
     5101 tcaggcgaag cgtttgctta gtatttgctg catttttacg atgtttcgta taatttaagc
     5161 gttctgctgc ttcaaaaatt ttttgctttg ttgctaagcc aacggaaaga tcaggatcat
     5221 agttgagaac tcttgaaaca gtagcaggag aaactcctgc caactgcgca atgtctttaa
     5281 ttgttgccat ttgtctctcc tcctttttta cgtttataaa atcgcagtaa atcgttcaaa
     5341 cgctgcctgt cctttttcat ctcgcttgaa tactccagcg tcttccagta cacgtgcaaa
     5401 aacctgacct acagattttt gtacgacatc ggtgaccgta tctttcgtca aatcaggatg
     5461 ttcttttttt aattgttctg cccacggacg atgatattca gccatctggt tttcttctcc
     5521 taataagaaa tgctctactt ctactagttc tggtttcaaa cgaggtggta aaacagcaag
     5581 ccccattact tcgatcaacc caatgttctc ctttttgata tgttggacat ctttatgtgg
     5641 atgaaaaatc ccatcaggat gttcttctga aacattgttg tctcgaagga caaggtccaa
     5701 ctcaaagtaa ttgtcccttc ttcgtgcaat tggcgtaatc gtatggtgtg gtgtaccatc
     5761 tgctgaaaaa gctctgatag atactgtttc atccgaatat gctttccatt tttccaatac
     5821 tgagttagct gcttcaataa gcaagttttt ctctgttgat tgcaaacgga tcacagacat
     5881 cggccatttc acgactcctg cgatgacttg cggataatct tctagtttga taagtttttc
     5941 tatcggtgct tttgccatag gaaattcatg acgtcctgcc tgataatgat catgagaaag
     6001 aatcgatcct ccaacaattg gtaagtcagc attcgaacca acaaagtaat gaggcaagac
     6061 ttcagtaatc cgaagcagtc tagcaaatgt ttcctttgtg attttcatcg ggcggtgttg
     6121 ttctgataaa atgatcgaat gttcattgta ataagcataa ggggaatatt ggaatcccca
     6181 gctttcaccg tctagattca ttcgaataat ccggtgattg gtgcgggctg gatagttcaa
     6241 gcgacctcta tatccttcgt tttccatgca aagcatgcag gtaggatagt ctacttttac
     6301 cgcctcgcgt tctgctgcga tttgttttgg atctttttct ggcttagata aattgattgt
     6361 gatttccagt tcaccatact ccgactctgc cggaaatttg atgttttttg cgatggctct
     6421 tgttttgatg tagtcatttt tcttacttaa attaaagaaa tactcagttg cttcctctgg
     6481 gcttttcgaa tagtgctgtg caaagaatgc attgacgact gaaggtggcg gtgtgagaaa
     6541 atccattaat tgcgcttcaa aaatctcttg ttctgctggc aattctgaaa gaacaccatt
     6601 ttctcttgcc ttagcgacaa gctgatccaa taagtctaca gattcttcct taactggtct
     6661 tacttcaatg ctttctagag catcttctcc taccatccct aaaagacgat tctgtaaata
     6721 taagcggtcc atttccatcc atccgccagc ttcgatcgca agtgtggcaa aatcacaaat
     6781 cgtttgactg attgacatat ctcattcccc tattcttcat aaccatttgg atggctgaca
     6841 tgccaatccc atgctgtttt gataatcgct ttgatatctg tgtattcagg tttccagccc
     6901 agaatctctc tcgctttttc acttgaagcg actaatcggc taggatctcc agctcttctt
     6961 ggtgctattt ctgctggaat ttcttttcct gtcacttctc tagctgcttc tagcatttcc
     7021 ttgactgagt atcctttgct gctgcctaaa ttgaagaagt tgctttcatt tccttctttc
     7081 aagtattcca aagctaaaat atgtgcagca atcaaatctt ctacttgaac ataatctctg
     7141 atacatgttc catctggtgt atcataatcg tctccataaa cagccaaggc ttttctttga
     7201 ccaagagcta cttgtaaaat gattgggaca agatgcgttt ctggtgtatg atcttctccg
     7261 atagatgcat ctgcttttgc tccggctaca ttgaagtagc gcaaagcgac atagcgcatg
     7321 ccatatgctt ggtcacacca cttcatcatt ttttccatca tcaatttact ttcaccatac
     7381 ggatttttag gattagctgg tgtatcttct gtgattggag actctttcgg ctctccataa
     7441 gttgctgcag tagaagagaa tacgatttta ttcacgttga actcgtgcat gacttcaagt
     7501 aagatttgca taccgtatac gttgttgttg aaatacatca atggtttttc gacagattct
     7561 cctactaaag agcttgcagc aaaatggatt actccttcaa tcggttcctt ttcaaatacg
     7621 gaacgtagaa attctttatc ccggatgtct ccttcataaa aatgagcatc tggatgtact
     7681 gcttgtttgt gacctgtgag caaattatct accacagcta cttgataccc cttttgaact
     7741 agctggtcta cagcgtgcga accgatataa ccggctccgc ctagtactaa aattgtcata
     7801 aaaaacactc ctttgattag taaaattgtg tttgttgatt ctatataatt taaaaaacga
     7861 agtttacttt tatggtgaaa acaaacaaag taaa
//
LOCUS       DAXLPC010000107         7628 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.108, whole genome shotgun sequence.
ACCESSION   DAXLPC010000107 DAXLPC010000000
VERSION     DAXLPC010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7628
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.108"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(17..715)
                     /locus_tag="ACF3UE_002423"
                     /pseudo
     CDS             complement(17..715)
                     /locus_tag="ACF3UE_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            794..970
                     /locus_tag="ACF3UE_002424"
                     /pseudo
     CDS             794..970
                     /locus_tag="ACF3UE_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1146..1715)
                     /locus_tag="ACF3UE_002425"
     CDS             complement(1146..1715)
                     /locus_tag="ACF3UE_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFD3635788.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1789..2112)
                     /locus_tag="ACF3UE_002426"
     CDS             complement(1789..2112)
                     /locus_tag="ACF3UE_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635789.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2266..3078)
                     /locus_tag="ACF3UE_002427"
     CDS             complement(2266..3078)
                     /locus_tag="ACF3UE_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635790.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3405..4280
                     /locus_tag="ACF3UE_002428"
     CDS             3405..4280
                     /locus_tag="ACF3UE_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3635791.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            4294..4617
                     /locus_tag="ACF3UE_002429"
     CDS             4294..4617
                     /locus_tag="ACF3UE_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635792.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            4614..5366
                     /locus_tag="ACF3UE_002430"
     CDS             4614..5366
                     /locus_tag="ACF3UE_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFD3635793.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5356..7527
                     /locus_tag="ACF3UE_002431"
                     /pseudo
     CDS             5356..7527
                     /locus_tag="ACF3UE_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2273 a         1512 c         1373 g         2470 t
ORIGIN      
        1 agaggggggg gattttttat cgttgtggaa tatttaaata ccaacgcttg tcatgaaaat
       61 cttgtgctcc acccttagta tttccttctg gatcgtttgt cgcacgcatc atgacgtata
      121 ctttcttatt agggaaatca cgcatattga aagatacatg atagccaaca tttcctaaag
      181 tattataagc ttgatttacg tctggtctat aaatcccatc agctcttact ctagctagtt
      241 cttttccagt attgtagtcc ataatgaaaa tatactcgta tttataatta gcaatgtgcc
      301 atccagctac atgcaagttt gcgttttcga tttctccgaa ctgatcaatg tgggcgtaat
      361 ttgttccatc tgtcagcgta gaatttgcag cacctgctcg agttggatca attactggtt
      421 tatcctccga agtagttgga ttatcatccg taaaaccatg agccaaatca taggctagtt
      481 tttctttact tacacctatt tcagaaagat aaccgtaagg atctgtatga tcgccccaaa
      541 tattttgtgt tacccataaa tgcgatttga ttcctggttg gttataagga gtgtctaatg
      601 ttaatggaat accatatttc attgctgaat ctcttgccaa ttcaacgtat actttatagt
      661 tcttttcaaa agtttcttta tcatgtgtgt gttgtaactc gatttgcaca ggacttttgg
      721 ctcacgaggt tgtcctactc tacatcttgc tgatagatat gctgaaagga aaacaccaac
      781 attatgtttt gctttttcag ctagaacgag acaagcagga atacctttag aagatatcaa
      841 aggtttttta ggtcataaag atgtttccac tacacaagtc tatgcccata tttctcccga
      901 agtgaaaaaa agatcaatga atcaactaga aaactatata gaagagcaaa taaaaaagca
      961 ctcaaattga gtgctttttt aagctcacta tcactaaaac tatcactaat tttatttata
     1021 agcgaacatg tttctatcac tgatttttta aatctagcga aaaaccctta tcttaaaggc
     1081 gttcgttcaa ttctttggca aggtcttcaa agcctggctt gcctagaagt gcgaacatgg
     1141 ttttcttata gctcatgtag aaaaattttc ttgatgatga ttttatccat caattgagat
     1201 tgactgtttt gctctcctat gatttcagct atgattgtcc gattttgcgg ttttcttctt
     1261 aactggtagt tgattttccc agtttccatc aactcgctaa gcatatccac gactccgcca
     1321 aatccggtct ttttcgtaat aaaacctagt gctaccattc gttcatctag attttttgct
     1381 gtaatcgtca caccagtaat gagcgagtgc tgtaatgttt gggccagctc ttccatccct
     1441 tcagcattgg atacgacgga agctgttttg ttaataggtt cttcgtttat ttcttttggt
     1501 tctttcctct ccactttcac tgtttgacga aggacatcta gttcttgcaa gagcgtttcg
     1561 tattgttctt gggtcagcat cacgccagct actttttcac gattaaatat atatacgcca
     1621 gttcccgcgt ctcgcgcttg agcaaataca tccatcggcg atcgtttcac ttctgtgatc
     1681 gaagatgtgg gaacttctaa tttctttaat tccaatggat ttcctccttt actaatcgct
     1741 ttttattata gcacagactg acttgttttg atcttttttc caaaggtttt atcggttttt
     1801 gcctaaccag taattgatat cggtaagaag tctttcgata ccaaatgaag gatggtacag
     1861 atacgttttt tgatcttcgt tatggtctag tggaaaaaaa tgatcgatga tcactagatc
     1921 tgcataccga ggcggcttat ttcgagtaca tacatgtata gagatccgtt ttcgatgtct
     1981 tagcgttttg ttcagtaccc cagcaagtct tcttgcttct tggtgttcat agcgaaaaaa
     2041 aaagacgatt ttcacttcag gagggtggac atctaaatac cctcgttcct ggagtgtttt
     2101 cagtaaaagc atcccccact ctactgcggg gtgtgcaagt gcttgttgga tcgctagccg
     2161 aaattgatat agtttatctt tggaattggg aaatttttct aatgtttcct gataataacg
     2221 aacttcttct atcagccggt catggatacc aattacgtaa cgaagtcatt cttggtaaag
     2281 tacttttgtc agctttgatt tgctttcgct ctcaaattcg ctattcagcc aaaacagcga
     2341 atcaagcttt tcagtcacaa tcgtcaattt ccgatagtct tgtgtctctt ctatccgttt
     2401 ccaccgcttt tcagtaatct ggttacagct caagcgcaaa attgctagat aatttttttc
     2461 ttttattggc aaaatctgct cctctctaaa tagcaattca ggaaacaatt caaagaatag
     2521 tgttcgactg tctcctaaaa tctcgatttc tgccggatcc tttctttgct tcaataattg
     2581 gatgaacatc tcagaaaagg actgctctcc atcatctgca aaaaaatgcg gaaaatcttt
     2641 caaaaagcaa aacagcagat atcttacttt tctttctgaa ccaaagatct gtgctttttt
     2701 ataagaaaaa gaaaggtggt actcgccaaa ccactttctc aatcgctctt gcgtagaacg
     2761 atcgtacttc tgctcgtaag gttcattcaa tagcagattt ttcagtaaac aaaacggggg
     2821 tgattggatc agaaaaacaa acaagagata aggttcgcta tatccttgat cataaactaa
     2881 ctgaacggtt ttcttatgaa gaatcagctg aatgggacag tcgctttccg ccaaacgttt
     2941 cagatgccga tccactgttt taacatcgat tttcagttct tcagctaaat cagcttttcg
     3001 ccagatcaaa tctttcatta gattgattag tgaaaataaa ttctgtgcat tttttgataa
     3061 tagtttttgc catctcatcg atcatttctc acctgatttc taaacatatt gtttgatcaa
     3121 aatgggttca ctcctaaaaa gataaaaaac tccctttcta tttatttaaa tacgcaaatc
     3181 ttcctcatta ttttttattt tactcaattt aatcgtattc tcatttcaaa acgaatgtac
     3241 tttaaaaaaa cataataaga tcactttgct tgtaggatgt attcccttcc attacaatga
     3301 aataaatagc gattttatga gaaggtgatg tgaaaatgga agaaaaaata gaagaatcca
     3361 aacaaaaaat cgatcagttg atataagaat tagaaaaagc ggtcatcggc aaacgttcaa
     3421 ctatccaatt gatgatcgtg gccctattag caggtggtca tgtcttattc gaagatattc
     3481 ccggtgtagg taaaacgtta ctggtcaaag cactagcaaa agctgtacag ggaaccttca
     3541 gcagagtcca atgtactcct gatctgctgc ctagtgatat tcttggtttt tccgtataca
     3601 attcacaatc aaaagagttt gaatttcgtc cgggaccgat ctttaccacg atcttgttag
     3661 cagatgagat caatcgtacg actcctcgta ctcagtcagc acttttagaa gcaatggccg
     3721 agaatcatgc aacgatcgac aacaatacat accctctaga caatcatttt tttgtcttag
     3781 ctacgcaaaa tccaatcgag tacgaaggaa catatccttt gccggaagca cagctcgatc
     3841 gttttttatt ccgactacaa atcggttatc cttcttttga tgacgaactt ttgctacttt
     3901 tggataaatt cgaaaaagtg ttggataact taaatgaagt attgaacagt tatgaaatag
     3961 aagaaataaa aacaaatgtg gcgaatgtct ttgtcagtcc cgaagtggca tcttatgcct
     4021 tgcagttagt gtcagcaaca agaagtcatg ctgccatcca gcttggcatc agtccacgag
     4081 gaagcctttc ctttattcag gcagcaaaag cttatgcttt aatccatggg agaaattacg
     4141 tcacgcccaa agatttgcag gatttagttc cttacgtgtt ttcccatcgc ctgatttttt
     4201 acgatcgttc attgaaggaa gacgaaaaga aacaaatcat tcatactctt gttgcacaaa
     4261 ttcctattcc tgtgaggtag attgaggtag acaatggaaa aaatcaaaga ttatttcatt
     4321 aattttgtgt tatttctggt atatttcatc attgtgcttt ttgctcttgt attcaacaat
     4381 tctttaggct ggttcttgtt ggcctttttt actctttatg tatcatggag cttgatttca
     4441 ttaagcagct ttctaaagaa actttcggtt acttgtacat tgcagccact cgtttatcgc
     4501 aaaaaaagta tgcaggttat tttttccata gcaaaaaaga gaactttttc tttacctctc
     4561 cctcgtttac aaatcggctt cccagcaatc tttgcagaaa aaaacaagag attttgattc
     4621 ttacaaataa accgcaagaa gtccaattgc tttggcagcc aaaagaaaga ggatgccatg
     4681 aaacattaac tgtcattttt acagcctatg atagtctagg acttttcaga aaaagtgcaa
     4741 aaagagagat ctcttttcct gtgactgttc tgcctgcttt ttgtaagatt caagcagaaa
     4801 aattacagag agttctggaa aaaaaacagc agctgaacgc gtaccaaaga ggtcttgatt
     4861 ttcgggaaca tcgcgcttat cgtccaggtg attctttcaa ccgaatcgat tggaaattgt
     4921 ctgctcatac tcaagagtgg ttataccgtg aatacgatta tcaagaagaa gaatgttctc
     4981 ctcttttttg cttttggggt tcgcccagtc caaaatttga acctctgcta gacttgtatt
     5041 tttctttatg gcatttgaga aaagaaaagc agccggaact tctgatatta ggcaaccgcg
     5101 cctttcatgg caaagacccc ggtcatacct attttgcttc tttggaagct ggcgatgaga
     5161 aaactttttt cgcacacttg aaaaaatatg caaaaaaaca aatcgtcctc tttgttcctg
     5221 agaattctcc tgaagtctca gaagctattg aaacattgtc aaaagatcga acggtttatc
     5281 ttgtttattt cgtagaaaaa caactcatgg tccaagaaaa agacaagata tgttcattgc
     5341 caggaggtga atggattgac gattaaacgg gaaaaatggc tgcgtggcgt ttactccttt
     5401 gtgatactaa gtgtaggtgc tccgatattt gtagtagcta atcaattgca aaacagctac
     5461 cttcttatcc taactattgg tgtcctatgc cttattgtct gctgtattcc taaaaaatgg
     5521 gtacgtttgc tgctttcttt gccagtaatg ataggttgtt tgtttttata ttttccttcg
     5581 aagacatttt ccatattatg gatcttacag tttttttcgt cagttacaga ggaattcttc
     5641 catctatccc aaggtaaact ttattatttg ccagaaaaga cagctttttt tctcataatg
     5701 ttgctgatct atttatttat tacattgacc gtggattacg actattggta cgcacccttt
     5761 ctttctttga tggcttactt catgatgctt accgtttttc ggaaaaaaga tttactgtac
     5821 gaaatgattg cggtagtaac tgttttgttc gtgtatctgg cagcaaggca atttttctcc
     5881 atccggttgt tgtcgagaaa cactcgattc cagtcattga ctacagttct gcttatttgt
     5941 ttcttaactt ttagcgctat cttgccttta tatcttccga aagtacacca atctctcgag
     6001 gaaacgagtg aaccgatccg agaatatctt aatgatgaag ggctttatga cacactccat
     6061 gagtatcaat taaccggaag tgcaagaaca ggcttcagtg agaatgatga acagcttggt
     6121 ggacctttat atgataatgg cgaagttgtt tttacagcga accaaaaagg aaatggctat
     6181 tggaagatcg aaaataaaaa tcattacacc ggttctggat gaatagaaga tcaggacgca
     6241 cccatccaac caatccaaga attccctgtt gacatcacga gctaccaaac cgttatagaa
     6301 gacaaagaaa acattacatt gaccctaaaa aaacaagctt tcttacctta tccttatgga
     6361 aatactacct tgactgattt ttcattagct agtggacaaa cgctttacta tttgcctgaa
     6421 agccagcgat tcattcctgt cccgaatgaa tcgacacgtt ctgcaacttt acaaacagaa
     6481 aggttagttt ttacgagaga agaattaaaa agcagtcagt taaaagctga tgatttagaa
     6541 aatcagcaga caaatcttca attgccaaaa agtttgccta aacgtattga ggacttggcg
     6601 gtcgaattga ccaaaaatga agcaacttta attcgtaaag tcgaagctgt ctaacagtat
     6661 ttaaaaacaa gcggaaattt ccgctattcc aaaacggata ccgggcatac tccaaaagaa
     6721 cacgattatg tggattattt cctctttgat tcaaaagtcg gctattgtga caacttttca
     6781 acttctatgg tcgtccttct tcgaacactt ggtatcccag ctcgctggac aaaaggtttt
     6841 acaaatgggc tcagaacagg cacagataat caagggaatg aggaatacag cattctcaat
     6901 agtcatgctc attcttggcc agaggtatac tttcctggat ttggctggct tccatttgaa
     6961 ccaacccctt catttgccaa tccaatgggt tcacaaccag ttgctgaaac aaccgaaacc
     7021 gtccagcctg ctatcgaaca accaaatgaa agcgaaaata tggcagaaac tatttccagt
     7081 gagagatctg aggtcattcc atcagaagaa acaacactca caccagctta taaaatcgtc
     7141 ttattcagcc ttggagtgtg tttatccgtc ttgttgttct ttctattgtt attcagaaaa
     7201 tctctgcgct ggacaagtta tcttatctat cttcattttt ttgcttctac taatacgatt
     7261 gcatatcaaa aacttcttaa ccctttggaa acattggtac cgcgcaaacc cgcagaatct
     7321 ttgcaggaat atagcctgcg aatagaacaa gaattcaagc tagatctgcg tttcattcga
     7381 ttaactactc aatatgaagc agaaatatat ggacgacaag cagatccggt aaaattcgat
     7441 aaaaaaacct atttagaaat aacgcatata ataagaaaaa cggtatacaa aaaaattctg
     7501 acaaaaggga gccgcttcaa aaaataagat aaaatttctg gagaatctac ttctcgaatg
     7561 ccgagaacca gctgattgag tatcgattac tcgaaaaaaa ggttgtgaca cgttttttgt
     7621 cacaacct
//
LOCUS       DAXLPC010000108         7607 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.109, whole genome shotgun sequence.
ACCESSION   DAXLPC010000108 DAXLPC010000000
VERSION     DAXLPC010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.109"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            251..1033
                     /locus_tag="ACF3UE_002432"
     CDS             251..1033
                     /locus_tag="ACF3UE_002432"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFD3635794.1"
                     /translation="MVKKIDFHIHTVSSHKDYDFSYSPEWLKKYVRAAELDAIAITNH
                     DLFDESNFKQIQYDLPNTKVFPGIELSLEEGHVNIIFPEEDSPNLVHFSEWLSTQNLG
                     QNGKVSTEDFCTHMSNWENGIYIFELGKSNALSVPEKLESICSVGGVANQLKFQTFYR
                     IEDALTPVLFSDAHADDNDPEEKRKNIEILKNKNTYLQIDNCSFQEIKNCLMDKTKVG
                     INLRYLRDVIDIENHTVSTGLNLIVGKRGTENQFFRNDKKIL"
     gene            975..2291
                     /locus_tag="ACF3UE_002433"
     CDS             975..2291
                     /locus_tag="ACF3UE_002433"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3635795.1"
                     /translation="MLVNEVLKTNFLETIKKYYDYEDIYEIAQFETSNANDFIKKQRT
                     EQGKNALDIWKKRYDSQFSAIQDYLKNNEEDFNQDVEKFVESVKQFAKDSTTSNSTSK
                     YQLIKESNLEEISTKNLETHLYKLLDLINSPDLWELLSNSVEKRRVFVETYSEVRNLF
                     VQKQQNNKVREKVNDILGSVKKIVQSKTGITPVVDCEFSKIIQKHQIEKEINNFMQKI
                     VCNTEIKKEKIYGYQIIVKLSPFINATQFRKDRTSEAVQDDLIVPYKSGQYITFLRNL
                     KKRSFFNPSILEEYLLHLEVNLLDSDGVPASGGQAVGFALMMRLEEAKTKPIILIDEP
                     EASLDNEYIRKELRDAIRNLSASSTVFVVTHNSTLGALLEPDYLIVTTKDKEKGYRVL
                     TGEFSSHLISTKSDTTESSYEKFVEAMEAGIETYKKKGEIYESLNS"
     gene            2272..2556
                     /locus_tag="ACF3UE_002434"
     CDS             2272..2556
                     /locus_tag="ACF3UE_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635796.1"
                     /translation="MKVLIVNSGKSKFVIGENNVEPENLSRDDLLMILNNIYESEENV
                     VIPSIEELDEIRNPIEKEIVQQIIQKISDFSNNVENIRQEVQAQFPVIED"
     gene            2594..2917
                     /locus_tag="ACF3UE_002435"
     CDS             2594..2917
                     /locus_tag="ACF3UE_002435"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635797.1"
                     /translation="MVGIDNDSNFKSYEFEKTYDFSVEIPIVDEDTGEYTREIELVAG
                     QITFFGDADWDSTEKEYVYNFSWEESTRTFSHYGNAPDKEDEFIKDFKEYLLQQGVER
                     YNIGW"
     gene            2968..3192
                     /locus_tag="ACF3UE_002436"
     CDS             2968..3192
                     /locus_tag="ACF3UE_002436"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_component: GO:0030127 - COPII vesicle coat [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0006888 - endoplasmic reticulum to Golgi
                     vesicle-mediated transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sec23/Sec24 zinc finger-containing protein"
                     /protein_id="HFD3635798.1"
                     /translation="MTERFPDTDWWCDRCGAHLNSQNNFDDYKYTWKCTECGFKNSIS
                     KDNIYESHEEYYNTGDDDSGLLRSIFKKLF"
     gene            complement(3579..4199)
                     /locus_tag="ACF3UE_002437"
     CDS             complement(3579..4199)
                     /locus_tag="ACF3UE_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HFD3635799.1"
                     /translation="MATKVFISFRFSDGKEIKDELVDLFDESTEVINRSEDVDRSQMS
                     KDTIQEYLYEKLKDTSVTIVLLTPEAVSYRKNWIGNYDDWIYDELRYSLEDRNNNRAN
                     GVVAVYTDDAKDMILESSSHYCAHCQETKSCRTLKSFDNLARKNMLNIKQSYKKNPCN
                     DLYDDSHDSYISLVSLEEFKQDYTKYIDNAKDKRDRLHEFNIYKRM"
     gene            complement(4199..5611)
                     /locus_tag="ACF3UE_002438"
     CDS             complement(4199..5611)
                     /locus_tag="ACF3UE_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HFD3635800.1"
                     /translation="MRQELFIKKFSKAIQEGNAAVFAGAGTSVDAGFVNWKNLVAPFA
                     NEIDLDIEKETDLVGLTQYYINKKRNRGSVNQEIIDQFSSQYAETEVMNLLTRLPIST
                     YWTTNYDKVIENGLKNNNRRGDIKRKTDDLAISIRDSDAIVYKMHGDVDSPNDAVISK
                     DDYERYSEKNSLFVTALRGDLVSKTFLFVGFGFEDPNLESILGKIKNLLGERTRDHYC
                     IQKKVLEQDYKNREEYSYAKIKQELKIEDLKRYGIDTVLVDDYSEIPKLILKIEEEYF
                     KNTIFISGSISDYNENWSQEKVNQFCYNLSRSLVSKNYKIISGFGLGVGSSVINGALD
                     EIYNTKYRHVSEHLGLFPFPQHDAGEKSLAKRWTENREQMISEAGICIFIFGNKLVNG
                     EVVLASGMMEEFRIAKERGKVIIPIGSTGFVAKEIFDEMKESGDYSYINDYWNDLENE
                     EDVIKVFNTINEIIEGVRFR"
     gene            complement(5641..6801)
                     /locus_tag="ACF3UE_002439"
     CDS             complement(5641..6801)
                     /locus_tag="ACF3UE_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003953 - NAD+ nucleosidase activity
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HFD3635801.1"
                     /translation="MGIVMRQYNNFYIKFQRQFKKAHGQVIETMPLEFSNKEYIERFK
                     YMFPDKILLIERERNYWYGKRIIRKNLSKIRCKGMSLETDSFILSTSKHIRKIKRESL
                     ASNEEMVKKVNTARTISLEKLKAESLRSKRKLNYIQEVEPPYLRNYRNRFFKTHDLHE
                     RLEIIRELSKYDSKEVREFFYAINGHIRNQSLKIEVQSYFQSLSLPFRLSRKKKGKKN
                     FIDNEIVKNKKGPDELKKRLYINDLEKIKRFDIFVSHNSRDEEKIIEFYKKFNKKGQV
                     VYIDWINDKYDLRREWCNASTVDIIKERIKQSDVFVLYFSGETLNSQWCTWELGYADA
                     LGKKICVYFSEDINRKGIPKFYVAYPELQMSKNIYVKIRGNEDILLKEWKKL"
     gene            complement(7207..>7607)
                     /locus_tag="ACF3UE_002440"
     CDS             complement(7207..>7607)
                     /locus_tag="ACF3UE_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3635802.1"
                     /translation="PTEPSKPTEPSEPTEPSTPTEPSTPTEPSTPTVPNKPVDTNPIE
                     NPVNTDTGVVIVAVEDSKPIIQLANGTTKKVEAKEIGANVQKDGTVTVKGSDGKMKVL
                     PKTGDTENIALSVLGSLMVLGSAFIFKKRI"
BASE COUNT         2556 a         1222 c         1118 g         2711 t
ORIGIN      
        1 tattattggg aatcccagct taaatcatag ataccgtaag ggattttatt ctttatttaa
       61 aactttgcaa cagaaccatt tcgaagatcc ttaatttaaa taaattagag gaggatttat
      121 attgccgcaa acaagttcta aaatcaatgt cactgagtgg ttgtttgtat ggcggatatc
      181 aagcatatta gtcagcgttt acatgatata atcaagacat gagtttccaa attattatgg
      241 aggtctacat atggttaaaa aaattgattt tcatatccac acggtttcta gtcataaaga
      301 ttatgatttt tcttattctc cagagtggct aaagaaatat gttcgagcag ctgaattaga
      361 cgcaattgct attactaatc acgatttatt tgatgaaagt aattttaaac agatccagta
      421 tgatttgcca aatactaagg tttttccagg tatagaactg agtcttgaag agggacatgt
      481 aaatattatt tttccagaag aagatagtcc taatctagtt catttttctg aatggctatc
      541 tacccaaaat ttaggacaga acggaaaagt atctactgaa gatttttgta ctcacatgag
      601 taattgggaa aatggaattt atatctttga actaggaaaa agtaacgcct tatcagtacc
      661 agaaaaattg gaatctattt gttctgttgg tggagtagca aatcaattga aatttcaaac
      721 tttttataga atagaagatg ctttaacacc agtattattt agtgatgcgc acgctgatga
      781 taatgatcct gaagaaaaaa ggaagaatat agaaatatta aaaaataaaa atacgtactt
      841 acaaattgac aattgctcgt ttcaagaaat aaagaattgt ttaatggata aaacaaaagt
      901 tggtataaac cttagatatt tgagggacgt aatcgatatt gaaaatcaca ctgtttcaac
      961 tggattaaat ttaattgttg gtaaacgagg tactgaaaac caatttttta gaaacgataa
     1021 aaaaatatta tgattatgaa gatatttatg agatagctca atttgaaaca tcaaatgcca
     1081 atgattttat aaaaaaacaa agaacagaac aagggaaaaa tgcgttagat atatggaaaa
     1141 aacggtatga ctcgcagttt tctgctattc aagactatct aaaaaataat gaagaagatt
     1201 ttaaccaaga cgtagaaaaa tttgttgaaa gtgtgaagca attcgccaaa gattcgacta
     1261 caagtaactc aacttccaaa tatcaactta ttaaagaatc gaatcttgaa gaaatttcca
     1321 caaaaaactt agaaacacac ttgtacaaat tacttgattt aattaatagt ccagatttat
     1381 gggagctgtt aagtaattca gttgaaaaaa ggagagtttt tgttgagaca tatagtgaag
     1441 taaggaattt gtttgttcag aaacaacaga ataacaaagt tcgagaaaaa gtaaatgaca
     1501 tactaggttc tgtaaaaaaa atagttcaat ctaaaactgg gattacccct gttgttgatt
     1561 gtgagttttc aaagataatt caaaaacatc agattgaaaa agaaattaat aatttcatgc
     1621 aaaaaatagt ctgtaatact gaaataaaaa aagaaaaaat ttatggatac caaattattg
     1681 tgaagctatc tccgtttata aatgctactc agtttagaaa agatcgtaca agtgaagcag
     1741 ttcaagatga tttaattgtt ccctataaaa gtgggcagta tattacattt ttaaggaatt
     1801 tgaaaaaaag aagtttcttt aatccttcta ttttagaaga atatctattg catttagaag
     1861 ttaacctgct ggattcagat ggtgtaccag catctggggg acaggctgtg ggatttgctc
     1921 taatgatgag attagaagaa gcaaaaacaa aaccaataat tttaatcgat gaacccgaag
     1981 cgtcacttga taatgaatac attcggaagg aattaagaga tgctataagg aatttgtctg
     2041 caagcagcac tgtttttgtg gttacacata attcaacatt aggagcatta ctggaaccag
     2101 attatctaat agtgactacg aaagataaag aaaagggata tcgcgtactt accggtgaat
     2161 tttcttctca tcttatctct acaaaatcag atacaactga aagtagctat gaaaaatttg
     2221 tagaagcaat ggaagcagga atagaaacat ataaaaagaa aggagaaata tatgaaagtc
     2281 ttaatagtta attcaggaaa atcaaagttt gttataggtg agaataatgt ggagccagaa
     2341 aacctttcta gagatgattt attaatgata ctaaataata tttatgaatc tgaagaaaac
     2401 gtggtgattc ctagtattga agagttagat gagattagaa atcccattga aaaagagatt
     2461 gttcaacaaa ttattcaaaa aatttcagat ttttcaaata acgttgaaaa tattcgccaa
     2521 gaagtgcaag cgcagtttcc tgttatagaa gattaaaatt tatatgctaa taaaaaataa
     2581 aggagtgagg aaaatggtag gaatagataa tgatagtaat ttcaagtcat atgaattcga
     2641 aaaaacatac gattttagcg tagagattcc aattgtagat gaagatacgg gggaatatac
     2701 tagagaaata gaattggtag ctggacaaat aacatttttt ggagatgcag actgggattc
     2761 aacagagaaa gaatatgttt ataatttttc ttgggaagag tctactagaa catttagtca
     2821 ttatggtaat gcacctgata aggaagatga gtttattaaa gatttcaaag agtatttatt
     2881 acaacaagga gttgagaggt ataatattgg atggtaaatg ttgaaattaa ttataaaaat
     2941 ttttaaatat gtagggagag atatactatg acagaaagat tcccagatac cgattggtgg
     3001 tgtgaccgtt gcggggcaca tctgaattct caaaataatt ttgatgacta taaatataca
     3061 tggaaatgta ctgagtgcgg ttttaaaaat agtatttcaa aagataatat atatgagagc
     3121 catgaggaat attacaatac aggtgatgat gattctggtt tactaagatc aatttttaag
     3181 aaattgtttt agtgctgaat tacttacaga ttttctgaga atgccttgaa acgttaatct
     3241 tccggtagtt aaaggagagg taatcacttt tctttttttt acttcattgt tccataactt
     3301 tatccaaggt gattaatttg acatagaact tgtgatggat ttatggacac gtgtttcaat
     3361 tcttttagag aaaaatcata ccaaaatagc agtgtccaga aatgaactat tttatggaca
     3421 tgagataaaa aagaaaaaca gccatttccg tttttctttt ttatctttgt gtctaaatat
     3481 ttgacattag tccaaacaaa agcactttat aaatcttgta cagaaaagtg ttgccttttc
     3541 atttattcta aagacaattt atgctaaatc aatgctcttc acattctttt atatatatta
     3601 aattcatgta gcctatctct tttatctttt gcattatcaa tatatttagt ataatcctgt
     3661 ttaaactcct ccaaacttac taaagaaata taagagtcat gactatcatc ataaagatca
     3721 ttacatggat ttttcttata gctttgcttt atattcaaca tattctttcg tgctaaattg
     3781 tcaaaagatt tcaaagttct acatgattta gtttcttgac aatgtgcaca atagtgtgaa
     3841 ctactttcta gtatcatatc tttagcatca tctgtatata ctgctactac gccatttgct
     3901 ctgttgttat ttctatcttc caaggagtat ctaagttcat cataaatcca atcatcgtaa
     3961 tttccaatcc aattctttct ataagaaacg gcctctggag ttaataatac aattgtaacc
     4021 gatgtatctt ttaacttctc atatagatat tcctgaatag tgtccttact catttgactt
     4081 ctatcaacat cttctgatct attaattacc tcagtagatt catcaaataa atcaactagt
     4141 tcatctttaa tctcttttcc atcactaaaa cgaaatgaaa taaatacttt tgttgccatt
     4201 atctaaatct aactccttca ataatttcat ttattgtatt aaaaactttt ataacatctt
     4261 cttcgttctc taaatcattc caataatcgt ttatatatga atagtcccct gactctttca
     4321 tttcatcaaa aatttctttt gcaacaaacc ccgtagaacc aattggaatt attacttttc
     4381 ctctttcttt agcaatccga aattcctcca tcattccaga tgcaagtact acctcaccat
     4441 taactaattt attaccaaat ataaaaatac agatcccagc ctcactgatc atttgttcac
     4501 gattttcagt ccaacgttta gctagagact tttccccagc atcatgttga ggaaaaggaa
     4561 ataatccaag atgctcactg acatgcctat acttagtgtt ataaatttca tcaagagctc
     4621 cattaataac actactacct actccaagtc caaaccctga tataatttta taattttttg
     4681 aaacaagtga acgcgataaa ttataacaga attgatttac cttttcttga ctccaatttt
     4741 cattgtaatc ggagatacta cctgaaataa aaattgtatt tttaaaatac tcttcctcta
     4801 tttttaatat caacttaggt atttcagaat aatcatcaac tagaactgta tctataccgt
     4861 accttttcaa atcttctatt tttaattctt gtttgatttt agcatagcta tattcctctc
     4921 gatttttata atcttgctct aataccttct tttgaataca ataatgatct ctagtacgct
     4981 ccccaagtaa attttttatc tttcccaaga tggattctaa attaggatct tcaaaaccaa
     5041 accccacaaa caaaaatgtt ttggaaacta agtcacctcg taaagctgtt acaaataggg
     5101 agtttttctc gctatatctt tcataatcat cttttgaaat aactgcatca ttaggtgaat
     5161 ctacatcacc gtgcatctta taaacaatcg catcgctatc acgaatactg attgctaaat
     5221 catctgtctt cctttttata tctcctctgc gattattatt ttttaagcca ttttcaatta
     5281 ccttatcata attagttgtc caatatgtag aaattggaag tcgtgttaac agattcataa
     5341 cttctgtttc tgcatattga ctagaaaatt ggtcaattat ttcttgattc accgaacctc
     5401 tatttctttt tttattgata taatattgag tcagtcctac aagatccgtt tctttttcaa
     5461 tatctaaatc aatttcattc gcaaacggtg ctacaaggtt tttccagtta acaaatcctg
     5521 catcgaccga tgttcctgca ccagcaaaca ctgctgcatt tccttcttgt atagctttcg
     5581 aaaatttttt tataaataat tcttgtctca tattaccctc atttctaatt tattataagc
     5641 ctataatttt ttccactctt taagtaaaat atcttcgttc cctctaattt tgacatatat
     5701 attttttgac atttgcaatt caggataagc tacatagaat tttggaatac cttttctatt
     5761 tatatcttct gagaagtaaa cacatatctt cttccctaat gcgtcagcat atcccaattc
     5821 ccaagtacac cattgggaat tcaaagtttc tcctgaaaag tataatacaa aaacatctga
     5881 ttgttttata cgctccttga taatatcaac tgtggaggca ttgcaccatt cacgccttaa
     5941 atcgtattta tcatttatcc aatctatata aactacctgt ccttttttat tgaacttttt
     6001 atagaactct ataatttttt cttcgtctct agaattatgc gatacgaata tatcaaatct
     6061 ttttatcttt tctaaatcat taatatataa tctctttttc aattcatctg gtcctttttt
     6121 attttttaca atttcgttat caataaaatt cttcttacct ttcttttttc tgctcaacct
     6181 aaaaggtaaa gataaactct gaaaatatga ttgaacttct atttttaatg attgatttct
     6241 aatatgccca tttattgcat agaaaaactc ccgaacttct tttgaatcat acttagaaag
     6301 ttctcttata atttccaatc gttcatgtaa atcatgagtt ttaaagaatc tatttcgata
     6361 attccttaaa tatggaggtt caacttcctg aatataattt aattttctct tgcttctcaa
     6421 ggactctgct tttaattttt ctaaagatat tgttcgggca gtatttactt tttttaccat
     6481 ctcttcgtta ctagctagac tctctctttt tatcttccta atatgttttg aagttgaaag
     6541 tataaaacta tcagtttcta aagacatacc tttacatcga attttggaaa gattctttct
     6601 aataatacgt tttccatacc aataatttct ttccctctct atcagcaata ttttatctgg
     6661 aaacatatat ttaaagcgtt ctatatattc tttattagaa aattctaatg gcattgtttc
     6721 tataacttgt ccatgagctt tcttaaactg tctttgaaat tttatataaa aattattata
     6781 ctgcctcatt acaatcccca tactcaataa gtccccccca ctacttaata ttattttgca
     6841 gtatattgtc ctctctgtct tttttctcaa tgttacacta aaatagattt tttggaaaac
     6901 tttgcaacag aacctatctc gttagttatc gcaccacttt tagtggttct aataatcaca
     6961 ttagttgatc attggttaga tgattagacg atggcaagca agttgctttc taactcacac
     7021 gcttgtattc gcaacaagtg aaaagaaaag ccgacctact agcaatatgt tattggtgtt
     7081 gcctagaacg attctaagcg cttgtttaat tttaaggtat acattcccct tcaaaacgtc
     7141 ctagaatgat tcaataaaag catggctgct agtgaaactt gcgaccacgc ttttataaat
     7201 acttaattag attcgctttt taaaaatgaa tgctgatcct aataccatta atgaccctag
     7261 gacagacaat gcaatatttt ctgtgtctcc tgtttttggt aaaactttca tttttccgtc
     7321 tgaaccttta accgttactg ttccgtcttt ttgaacgttt gcaccaattt ctttagcttc
     7381 aactttcttt gttgttccgt ttgctaattg aataatcggt ttactatctt caactgcaac
     7441 aatcacaacg cctgtatctg tattaactgg gttttcgatt gggtttgtgt ctactggttt
     7501 gtttggtact gttggtgtac ttggttccgt tggtgtactt ggttccgttg gtgtacttgg
     7561 ttctgttggt tcgcttggtt ctgttggttt gcttggttct gttggtt
//
LOCUS       DAXLPC010000109         7600 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.110, whole genome shotgun sequence.
ACCESSION   DAXLPC010000109 DAXLPC010000000
VERSION     DAXLPC010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.110"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(138..428)
                     /locus_tag="ACF3UE_002441"
     CDS             complement(138..428)
                     /locus_tag="ACF3UE_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635803.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(546..806)
                     /locus_tag="ACF3UE_002442"
     CDS             complement(546..806)
                     /locus_tag="ACF3UE_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635804.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(943..1356)
                     /locus_tag="ACF3UE_002443"
     CDS             complement(943..1356)
                     /locus_tag="ACF3UE_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFD3635805.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="ACF3UE_002444"
     CDS             complement(1812..2297)
                     /locus_tag="ACF3UE_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635806.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="ACF3UE_002445"
     CDS             complement(2436..2651)
                     /locus_tag="ACF3UE_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFD3635807.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="ACF3UE_002446"
     CDS             2875..3675
                     /locus_tag="ACF3UE_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFD3635808.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="ACF3UE_002447"
     CDS             3694..5562
                     /locus_tag="ACF3UE_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFD3635809.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="ACF3UE_002448"
     CDS             5555..6046
                     /locus_tag="ACF3UE_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFD3635810.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /locus_tag="ACF3UE_002449"
     CDS             6034..6588
                     /locus_tag="ACF3UE_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFD3635811.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..>7600
                     /locus_tag="ACF3UE_002450"
     CDS             6606..>7600
                     /locus_tag="ACF3UE_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFD3635812.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2237 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DAXLPC010000110         7581 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.111, whole genome shotgun sequence.
ACCESSION   DAXLPC010000110 DAXLPC010000000
VERSION     DAXLPC010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.111"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            130..2205
                     /locus_tag="ACF3UE_002451"
     CDS             130..2205
                     /locus_tag="ACF3UE_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HFD3635813.1"
                     /translation="MKEVINIESNYFSRKFDDELLIIEAWGENAIRIRSFVDMNYEDR
                     QNSLIDKPNSLNKVIINQYENKTELINGKIRAVLDHRDRLTFYNEKNDVLLKEYIRLR
                     AVKHDDGGEDAGSVEVTKDFNSTLKLKSREYRSNMDGKFQVTTRFESDPKEKIFGMGQ
                     YQHSYLDLKNTVLELAQRNSQVSIPFYISSLGYGFLWNNPGIGEVSFAKNITRWKMYS
                     SDYIDYVIISGNEPKEILRNYSNLTGKVPKMPDSLLGLWQSKLRYRSPEEVMDVVEKY
                     HKRGIKLSTIAIDYFHWPKQGEYCFDEEYWPNPEKFLKTLKTDYGVEPIISIWPTVQT
                     DAENYEKYLENGYLVKVNRGVRLTMQIQGNTIFIDMTNSEARKYVWSLIKKNYVDKGI
                     NYFWLDVAEPGYSVYDFDNYRYKKGTDLYSGNLYPIDYLSMIYEELSNEQPVITLVRG
                     GWAGAQRFGALLWSGDIDSSFEAFRNQVNTGLNVGLAGIPWWTTDIGGFHGGNPEDPE
                     FRELLIRWFQYATFSPILRMHGDRLPHSKPLSDHGGGSMVTGAPNEIWSYGIEVEQIL
                     TKYIKIREALKPYISTLMDKAHRFGDPIMRTLFYEYPSDNNTWAVEDTYLFGDTFLIA
                     PIVNYKETVREVYLPINENWTNIWTGEEYDGGQTLDVEADISMIPVFIKTNQKDKFSK
                     LLSIIKEEI"
     gene            2205..2990
                     /locus_tag="ACF3UE_002452"
     CDS             2205..2990
                     /locus_tag="ACF3UE_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3635814.1"
                     /translation="MEISVIQLGLIVLYGFFINFEKNSTMFGTYQPVTAGFVTGLILG
                     DIKTGLFIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTGQESSVGISIGIPV
                     ALLMVQLDIIRNTIGIWMVHKAEAGVKRGDYSMISKMQMFGVFLTAATTGIPVALAVI
                     FGPSLINTILAHTPEWLTNGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVMSVY
                     LKMPLLGVALIGAAIALIIYKKNSQNVINNTVVNTIGGMDEDE"
     gene            2983..3795
                     /locus_tag="ACF3UE_002453"
     CDS             2983..3795
                     /locus_tag="ACF3UE_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3635815.1"
                     /translation="MNSLETTKLGVNSKIKKSVLWRWFFTSSVSSNYEKMQALAYCYA
                     VLPFLKVTYKNKPEALQKAVLNHLQFFNTNPWVAPYILGINIAMEENSDENTEEAVTS
                     IKTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPVGIILWIAVSVALKMISIPL
                     FRIGYTSGTKLITTIEKSLKLLTESTSILGLMVVGALIPSVVKTNVVLDFKQGDFSMR
                     GQEILDQIMPGLLPALLVGLVYWSLKKNVKPIYLILGVMVLSIVLATLGILK"
     gene            3815..4297
                     /locus_tag="ACF3UE_002454"
     CDS             3815..4297
                     /locus_tag="ACF3UE_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFD3635816.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDTVANND
                     IQKQVLRMAVPAGISSSIITEEKAITNIKNGKYEGQNVLLIVKSPVDLLSFIENDLQI
                     DRINVGNMSNRKGTTVLRPNISVTNEERNAFEKLLNLGVEITTIMTPDDKKTYLKDIL
                     "
     gene            4312..4716
                     /locus_tag="ACF3UE_002455"
     CDS             4312..4716
                     /locus_tag="ACF3UE_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3635817.1"
                     /translation="MTNEIILMSHGLMAEEILNSAKMILGNQINYPVVSMTQNDGIEG
                     TINKLNKILEETSDIRNIIILVDLMGGTPANVAMMKASMDKRIQVVTGMNLGMVLESY
                     FKINEEKLAEHLIEIGKSSIKIPEIQMDGGEE"
     gene            5302..6492
                     /locus_tag="ACF3UE_002456"
     CDS             5302..6492
                     /locus_tag="ACF3UE_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HFD3635818.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFKGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGAFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            6921..>7581
                     /locus_tag="ACF3UE_002457"
     CDS             6921..>7581
                     /locus_tag="ACF3UE_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635819.1"
                     /translation="MKSKIILGGLLLSTTAFVSLQSPQITSAESLTNSAEIIVPLNLK
                     VKAHYTNGLPLEAGKEVRLRNLTDGSTEVLKKQVDANGEVIFTEQDGIKKEVNYGIET
                     DGVRNGYTVRYDLGGEKEKDITVNLPGSELPLSLKVKAHYTNGLPLEAGKEVRLRNLT
                     DGSTEVLKKQVDANGEVTFTEQDGIKKEVNYGIETDGVRNGYTVRYDLGGEKEKDITV
                     NL"
BASE COUNT         2727 a         1033 c         1524 g         2297 t
ORIGIN      
        1 tcgagaaaac aaattaaaaa gcagaattct agtcaaaata cttaaattaa attgatatgt
       61 atatgtatgc gattacaatt gctagtgttg taataagagt taactaatta agaagaaaag
      121 gaaagtggga tgaaagaagt gataaacatt gaatcaaatt atttttcaag aaaatttgat
      181 gatgaattac tgattattga agcatggggg gaaaatgcta ttagaatacg ttcatttgta
      241 gacatgaact atgaagatcg acaaaactcc ttaattgata agcctaattc cctaaataaa
      301 gtgataataa atcaatatga aaataaaaca gaattaatta acgggaaaat aagagcggta
      361 ctagatcatc gtgatcgttt aactttttat aatgaaaaaa acgatgtctt actaaaagaa
      421 tatattagat taagagctgt taaacatgat gatggtggtg aagatgctgg ttcagttgaa
      481 gttacaaagg attttaattc tacattgaaa ttaaagtcaa gagaatatcg ttccaatatg
      541 gatggtaaat ttcaagtaac tactagattt gaatcagatc caaaagaaaa aatattcgga
      601 atgggtcaat atcaacattc ttatcttgat ttgaagaaca ctgttttaga attagcgcaa
      661 agaaactcac aggtgtcaat tccattctat atatctagtc ttggatacgg ttttttatgg
      721 aataatcctg gtattggaga agtttctttt gctaaaaata taactcgatg gaaaatgtat
      781 tcttctgatt atatcgatta tgtaataatt tcaggaaatg aaccaaagga aatacttaga
      841 aactatagta atctaactgg aaaagtccct aaaatgccag atagtttatt aggattatgg
      901 cagagcaaat tacgatatag atcaccagag gaagtgatgg atgtagtaga aaagtatcat
      961 aaacgtggaa taaagctttc aactatcgct attgattatt ttcactggcc aaagcaagga
     1021 gaatattgtt ttgatgagga atactggcct aatccagaaa aatttttaaa gactttgaaa
     1081 actgattacg gagtggaacc aataatctca atttggccta cagtacaaac tgatgcagaa
     1141 aattatgaaa aatatttaga aaatggttat ctagtaaaag ttaatcgtgg agttcgatta
     1201 accatgcaaa ttcaaggaaa cactattttt attgatatga caaatagtga agctcggaaa
     1261 tatgtttgga gtctaattaa aaagaattat gttgataaag ggattaatta tttctggtta
     1321 gatgtagctg agccaggata ttccgtttat gactttgata attatcgtta taaaaagggg
     1381 actgatttat atagtggtaa tttatatcca atcgattatc tttcaatgat ttatgaagaa
     1441 ttaagtaatg aacagcctgt aattactctt gttagaggag gatgggctgg agcacaaaga
     1501 ttcggtgcat tattgtggtc tggagatatt gattctagtt ttgaagcatt tagaaatcaa
     1561 gttaatactg gactaaatgt aggtttagca gggattccct ggtggacaac tgacataggt
     1621 gggtttcatg gcggaaatcc agaagatccg gagtttagag aattgctaat tcgttggttt
     1681 caatatgcta ctttttcacc aattttaaga atgcacggtg accgattacc ccatagtaaa
     1741 cccttatcgg atcatggtgg aggttcgatg gttactggtg caccaaatga aatatggtca
     1801 tacggtatag aagttgagca gatattaact aagtatataa aaatacgtga agcgttgaaa
     1861 ccgtatatca gtactttgat ggataaagct catagattcg gagatccgat catgaggacg
     1921 ctattttatg aatatccttc agataataat acttgggctg tagaagatac ttacttattt
     1981 ggagatacgt tcctaattgc accgattgta aattataagg aaacagtaag agaagtttac
     2041 ttaccaataa atgaaaactg gaccaatata tggacaggtg aagaatatga tggcggacaa
     2101 acgttggatg ttgaagcaga tattagtatg atacctgttt ttataaagac aaatcaaaaa
     2161 gataaatttt caaaactatt aagtataatt aaggaggaga tctaatggag ataagtgtta
     2221 ttcaacttgg tttaattgtg ttatatggtt tttttattaa ttttgagaag aattcaacaa
     2281 tgttcggaac ctaccaacct gtaacagcgg gatttgtaac tggtttaata cttggagata
     2341 taaaaactgg gctttttatt gggggaacct tacaattatt gtctttagga attagtaatt
     2401 ttggaggagc ttctatacca gactatcaaa ctgcaagtat tgtcgcaact tttatcacca
     2461 taacaactgg tcaggaatct tcggtaggga tttctattgg tataccagta gcactattaa
     2521 tggttcaatt agatattatt agaaatacaa ttggtatttg gatggttcat aaagcagaag
     2581 caggtgtaaa gcgaggagat tatagtatga tctccaagat gcaaatgttt ggagtattct
     2641 taacggcggc aacaacgggc ataccggttg cgttggcagt aatttttgga ccatctttaa
     2701 ttaatactat tcttgctcat actcctgaat ggttaacaaa tgggttaaca gttgctgggg
     2761 gattattacc agctgttggt attggtttat tgcttcgata cttacctgca aaagaatatt
     2821 tcagttatct tgttatcggt tttgtaatgt ctgtttactt aaaaatgcca ttattaggag
     2881 tagcattaat aggcgctgct atagctttaa ttatttataa aaaaaatagt cagaatgtaa
     2941 ttaataatac cgttgttaat acaataggag gtatggatga ggatgaatag cttggagacg
     3001 acaaaacttg gtgttaattc caaaattaaa aagagtgtat tatggagatg gttttttaca
     3061 agctcagttt cttcaaatta tgaaaagatg caagctctag catattgtta cgctgtatta
     3121 ccattcttaa aagttactta taaaaacaaa ccagaagcgt tacaaaaagc agtactaaat
     3181 catttacaat ttttcaatac aaatccttgg gttgcaccgt atattttagg tattaatata
     3241 gctatggaag aaaattcaga tgaaaatact gaagaagcag tgacatcgat taagacagga
     3301 cttatggggc cagtagctgg attaggtgat agtctatttg tagttattcc atggactata
     3361 tttggggcta ttgcagcaaa tatggcaatt gatggtagtc cagtaggaat tattttatgg
     3421 attgctgtaa gtgtagcttt aaagatgata agtataccat tatttcgcat aggctatact
     3481 tcaggtacga aattaattac tactattgaa aaaagtttaa aacttttaac tgaatcgact
     3541 tcaattttag gattaatggt tgttggagca ttaataccat ctgttgttaa aacaaatgtc
     3601 gtcttagatt ttaaacaagg tgatttttct atgagagggc aagaaatact agatcaaata
     3661 atgccaggat tattacctgc acttttagtt ggtttagttt actggtcttt gaaaaaaaat
     3721 gtaaaaccta tttatttaat tcttggtgtg atggttctgt ctattgtttt agctactcta
     3781 ggcattttaa aataaatgat aggaggaaat ttttgtggaa atgaagggta taaaaaatat
     3841 tagaattgac gatcgattaa ttcatggtca agtagctaca atgtggagta ataaattagg
     3901 tgtgactcgt ttgatggttg taaatgatac tgttgcaaat aatgatatac aaaaacaggt
     3961 gctaaggatg gcagtccctg caggaatcag ttcttcaatt ataactgagg agaaagcgat
     4021 taccaatatt aaaaatggaa aatatgaagg gcaaaatgtg cttttaatag tcaaatcccc
     4081 agtagactta ttatcgttta tcgaaaatga tttacagata gataggatta acgttggcaa
     4141 catgtctaat cgaaaaggaa caacggtttt acgtcctaat attagcgtta ctaatgaaga
     4201 aagaaatgcc ttcgagaagc tattaaatct tggtgttgaa attactacaa ttatgacacc
     4261 agacgataaa aaaacttact taaaagatat tttataaggg gaataagtgc gatgactaat
     4321 gaaataattt taatgagtca tggtttaatg gctgaggaaa tattaaattc agctaaaatg
     4381 atacttggaa accagattaa ttatccggta gtttctatga cacaaaatga cggtattgaa
     4441 ggaacaataa ataaattgaa taaaatactg gaagaaacaa gtgacatacg aaatattatt
     4501 atattagtag acctaatggg aggaacacct gcaaatgtag ctatgatgaa agcaagtatg
     4561 gataaaagaa ttcaagtagt aactggaatg aatctaggga tggtattaga atcatacttt
     4621 aaaattaatg aagaaaaact tgctgagcat ttaatagaaa taggtaaaag tagtattaaa
     4681 atacctgaga tacagatgga tggtggagaa gagtaattat aatgaaggaa gaatagttct
     4741 gttaatctca attgaaaaag tttaaatcaa aacaaaagga aatctatttt cgatattaat
     4801 atgattcgtt ttctacataa tatcaaaatt agatacgaag ccatagtaag aaatatgttt
     4861 ttttcattat aatcttaaat aattaatact agcgaaatag aggaatgtta aaagggctct
     4921 ttttggaata gcacggtata gctagtgctt gaactgctat aaaaaccaaa tagttaaata
     4981 gtaaagcaat aatggttcga gtgtactatt tggaggacaa tctaagattg aagatgcttt
     5041 caagtataag tggtattttc aatgagacgg ttaggaaatt agtgccagag taggtactaa
     5101 ttctagatgt aacaatctta acagcggtgg gatatgatct atatgcaaat attatatagt
     5161 tgtgttaaag tttttttgat atatatatga atgttgtcca atcaaatgag agtgtaaaat
     5221 attttgtgta aatagaaaaa aggaagtccc ttctgtagaa tagagttacc acaacacatt
     5281 cacagaagag aggacttccc tatgaacgat tttactacag aaattctaaa gactctagcg
     5341 aacaaaggcg atttgaatga attattccgt gtccatttgg agaaagcagt caatacgctt
     5401 ctcaaaacgg agttaacggc tttcctagat tacgaaaagt atgatcgcat tggttttaac
     5461 acgggtaatt ctcgtaacgg ctcctatgac cgtacggtca agaccgagta tggggaactt
     5521 catctccaga ttccgcgcga ccgcaatggt gagttcaagc aacagactgt tcctgcttat
     5581 agacggacga atgacacgtt agaggagacc gtcattcacc tcttccgaaa aggtattacc
     5641 atgtcggaaa tcgcagactt gattgagaaa atgtatgggc attactacac gccccaaacc
     5701 atgtccaata taacaaaatc atttacagaa gaggtaacgg cgtttaaagg gcgggagctt
     5761 catgaccgtt atgctgctat ttatatggac gcaacgtata ttccgttaaa gcggaaaacc
     5821 gtcgccaagg aagctattca tatcgcagtt ggcattcgcc cggacggatc aaaggaagta
     5881 ttgagctatg cgattgcacc gactgaatcc atcacgattt gggaggaaat tttattggac
     5941 cttcaagagc gcggtttgaa aaatgtcctc ctgttcatca cggatggctt aaaggggatg
     6001 gtaggagcga ttagtcggtt ctatcccaaa gctcgttttc aacattgttg tgtacacgtt
     6061 tcccgtaata tcagtcacaa agtgcgtgtc gatgatcgta aggaagtctg tgatgatttt
     6121 aaaatggtgt atcaagcctc atctaaagag gtggcgttgg aagcacgtgg tgcttttgcg
     6181 gaaaaatgga aaaccagcta tccaaaagtg gttgaatcga ttctttcgaa cgatcacttg
     6241 ctcactttct atgatttccc cttggccata cgcaagagta tttattctac gaacttgatt
     6301 gaatccttta ataagcaaat caagaaatac agccaccgca aggaacagtt ccaaaacgaa
     6361 gagtcgatgg aacgtttctt agtctcgtct tttgatactt acaaccaaaa attcctaggt
     6421 cgcagtcata aaggctttca acaggccgaa ggcgaacttg aacaaatgct aagccaactg
     6481 attgagaatt agaaacaatc tgcagtaggg aagaatcatt tacacaaaat tattgacgct
     6541 cccaatcaaa ttctagaaat gctttagact ataaaattta ttatacgggg aaaatgcaac
     6601 tttttagcta ataaagctga agttgcattt ttagctatct gaaaaaaatc gagttgaatt
     6661 ttatattaat ctatttttgg cacttcaata aaaaatgaac cttcattttt attgacattt
     6721 tttaagtaaa tttgtaaaat cgtttttata aaacgtaata gttacgtttt ataaaaacta
     6781 attagagagg agatagggac atgtctctat tcaataaaac aatggtttcc ttttgtagta
     6841 ttaagaattt taatagctag aatattaaca taaaaactat tttttgagct taataaatag
     6901 aatttaagga gaatgatatt atgaaatcaa agataattct tggcggtttg ctactatcta
     6961 caacagcttt cgtttcacta caatccccac aaattaccag tgcagaaagt ttaacaaatt
     7021 cagcagaaat tatagtaccg cttaatttaa aggtgaaagc acattacaca aatggattac
     7081 cacttgaagc gggaaaagaa gtacggttaa gaaatttaac agatggatca acggaagtac
     7141 ttaagaaaca ggtagacgct aacggagagg taatatttac cgaacaagat ggcatcaaaa
     7201 aagaagtaaa ttatggcatc gaaacagacg gagtaagaaa tggctataca gtaagatacg
     7261 atcttggtgg agaaaaagag aaggacataa cagtgaattt gccaggatcc gagttaccac
     7321 ttagtttaaa ggtaaaagca cattacacaa atggattacc acttgaagcg ggaaaagaag
     7381 tacggttaag aaatttaaca gatggatcaa cggaagtact taagaaacag gtagacgcta
     7441 atggagaggt aacatttacc gaacaagatg gcattaaaaa agaagtaaat tatggcatcg
     7501 aaacagacgg agtaagaaat ggctatacag taagatacga tcttggtgga gaaaaagaga
     7561 aggacataac agtgaatttg c
//
LOCUS       DAXLPC010000111         6914 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.112, whole genome shotgun sequence.
ACCESSION   DAXLPC010000111 DAXLPC010000000
VERSION     DAXLPC010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.112"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            69..950
                     /locus_tag="ACF3UE_002458"
                     /pseudo
     CDS             69..950
                     /locus_tag="ACF3UE_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            963..2573
                     /locus_tag="ACF3UE_002459"
     CDS             963..2573
                     /locus_tag="ACF3UE_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3635820.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRMGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2650..3309)
                     /locus_tag="ACF3UE_002460"
     CDS             complement(2650..3309)
                     /locus_tag="ACF3UE_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFD3635821.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(3592..4257)
                     /locus_tag="ACF3UE_002461"
     CDS             complement(3592..4257)
                     /locus_tag="ACF3UE_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFD3635822.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(4404..5009)
                     /gene="dhaL"
                     /locus_tag="ACF3UE_002462"
     CDS             complement(4404..5009)
                     /gene="dhaL"
                     /locus_tag="ACF3UE_002462"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFD3635823.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(5037..6047)
                     /gene="dhaK"
                     /locus_tag="ACF3UE_002463"
     CDS             complement(5037..6047)
                     /gene="dhaK"
                     /locus_tag="ACF3UE_002463"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFD3635824.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(6022..6417)
                     /gene="dhaM"
                     /locus_tag="ACF3UE_002464"
     CDS             complement(6022..6417)
                     /gene="dhaM"
                     /locus_tag="ACF3UE_002464"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFD3635825.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            6571..6891
                     /locus_tag="ACF3UE_002465"
     CDS             6571..6891
                     /locus_tag="ACF3UE_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFD3635826.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
BASE COUNT         1834 a         1448 c         1334 g         2298 t
ORIGIN      
        1 taaaaccttt ttattaaact atttaatctt gtttagtata tatttttaga aaaaggagtg
       61 gggtttttat ggcagaaatc gtcaaagtca cacatttgaa aaagagcttt ggtcgtttcg
      121 aagctttaaa agatgtctct ttcaccgtac attcaggtga agtcgttgga tttatcggac
      181 caaatggttc tggaaaatcc acgacgattc ggacactttt agggattata aaaaaagacg
      241 gcggaacggc aacgattttt gggcaagatg tatgggaaga tagtttatct atccatgaac
      301 gtctttctta tgttccaggc gatatctctt tgtagggaaa tttgactgga ggagcgatca
      361 tcgatctctt catgaagctt catggaaaag ggagtgctca aaaaaaagat gaactgattc
      421 aacgtttctc tcttgatcct aagaaaaaag caaaaaacta ttcaaaagga aatcgccaaa
      481 aagtgggctt gattgctgct ttggctgttg attcggatct ctatttattt gatgagccta
      541 cttctggttt agatcctttg atggaaacga ttttccaaga agaagttgaa aaattgaaag
      601 aacagggcaa atccatccta ctttcttctc atattctcag tgaagtcgag cgactagcgg
      661 ataaagtcgt gatcatacgc gaaggaacag tcgtagaaga aggaacactc gatgaattgc
      721 gtcatttgac tcgttcgacc atcactatag aaacagaagc agagaatagt cacttagcac
      781 aattgaacgg tgtccatgac tttgtgcaaa aaggtcacct cgctcaattt gctgctgata
      841 acgaagcttt cgatgtgatt ttagctgaag cgtccaaatt aggtgtgaaa aaatttgaat
      901 ctattccacc gactcttgag gatttattca tgagacatta tgaaggatga ggaggaagcg
      961 aaatgactga taaattttca cgctggtcca cccttttttc tcaaaacctt agccgtgact
     1021 ggaaaaagat cctgatatgg ctagtcggtg tcactgcttt ttctggtggt tttgtccctg
     1081 cgtttgaaga attgacttcc ggacaaggat tagctggatt atacgaaacc ttgcaaaacc
     1141 cggcaatgat tgcaatggtc ggaccaactc cagcttcgaa tgctgctgag tatactttag
     1201 gagcgatgta tgcaaatgaa atgttgcttt tttgcagttt gtttgctgct gtgatctctg
     1261 ttttacacgt ggtgagccaa acgagaaaaa aagaagaact tggtctgatt gaacttattc
     1321 gttcctttcg agtcggacgt caagcaaact ctttagctgt catcgctgaa agtattctga
     1381 tcaatttgct tttagcaata tcgatcagct gtacgatgat ttttttccaa gcagattcga
     1441 tcactgcaga aggtgcttgg ctttttgggc tatctgtagg tagtatgggg attttgggga
     1501 gtgccgttgc actgtttgct gcacaactga tgccaagttc agccagttcg aatggtctgt
     1561 ctttagcgtt tttaggtgga ctttaccttc tacgagcaat aacagatgta gctgattcct
     1621 ccctttcgat gtggaatcct ttaggctggt cttatttgac ctatccattt acaactaaca
     1681 actggattcc tttgctttat ttgtttttgt tcagtctaat cttgataatc agttcatttg
     1741 ttttagagga acatcgagat ttgaacaccg gctatatccc cgaacgtgaa ggaaaaccgt
     1801 atgctaaacg ttctctttta tccttgcgtg gtttattatt ctatctaaat aaagggatga
     1861 caatcagttg gcttatcact tttggtttga tgggggcggc atacggctct atctacggga
     1921 atatgcaaca gtttttagaa agtaacgact taatgaaaca gatgtttatc caatctggcg
     1981 tctcaattga aaaaaacttt acaagcacga tcatggtcgt cttgatttgt ctagctgcta
     2041 ttttaccaat tgctagcatc aatcgtttat ttacagaaga aacccacgga cgtatgaatc
     2101 agctgttcgc aacaaaaatt tctaggaacc aactttattg gaccaatatg ttactagcta
     2161 ttctatttgc tatattggca atcctgatta gttctggtgc actagggctt tctgctttgg
     2221 cttcgatgaa ggatgcgaaa gacatggatc tattgatgtt tcttaaagcc gggttcaatt
     2281 tcctgcctgc cgttttagtg tttatcggaa ttagtggctt tctattcgga tggcttcctc
     2341 gaatgggtaa acttgcttat atctacttag cttactcctt tgcactcaat tactttggcg
     2401 gaattttgga tttaccagaa tggttttcca aaacagctgt ccctagctgg gttccacgga
     2461 tgccaaacga ttcttttgat ctttccgtgt tccttacgtt atcatgtatc agccttgcac
     2521 tgttcgtcct tggttctatt ggttataggc gaagagactt actagaagga taataaaaaa
     2581 gcatgtacaa tttcatgcta gcctccaaat ctgggtcaaa aatccaacat ttggaggtca
     2641 tttttttatt tacaagtctt ctaactgctc tttatcaatg atccagactt ctcgattctt
     2701 tctttttaca taaccattct cctctaataa tttaaatttt ctagataaag tttcgggggt
     2761 cgtaccgata aatgcagcaa gttctttcat tttcattggc aggaaaaagt gatccttccc
     2821 tgtcgcttta gctaagtcaa gcagatagac agcgactcgt tcttctactt tttccatcat
     2881 caaaaaagtt gtctgctgct gtacttttgt taatttctca acgttgattg ctaaaagttt
     2941 cagactaagg gcgggataat gcagtaagag ttccgagaaa tctttttgtc tcaatatgca
     3001 aatttccgtt ttttctagtg cttcgccaaa taaagactca tttggaacgc ctagcaactg
     3061 gctctctccc tcatatccgc ccggctctat tactcgtaaa agctgttcct ttccgctagc
     3121 agataattga tacactttca tactgccgga ggccacgatc actaattgag gttctccatt
     3181 cggcgcaaga atctgttctc ctttttccac atagtgatgt ttgacaagtg cgtgtacttt
     3241 ttcttgatct tgctgtacta agtgattgaa caaaggaaca aatgaaacac ataaatgatc
     3301 atgactcata atctctcctc cttctaaaca gctatttcta ataaagaaac ataacttccc
     3361 ttattccaac tgataatttt cttttatcat agcataaacg tcaagcgaac cagataccag
     3421 caaatagagt ggatttcttt ttgtcccttg ctttattttc cttcttttga gaccttaagt
     3481 aattgattcc tatcaatttt ttaaatattt actttttgaa taatcaaaaa caaaccttca
     3541 ctcgcaagcc gagagtaagg tttgtttttc gcattgctta tttcgtgttg tctattgaaa
     3601 tttttccgca cctagctttt gatatagtgg tgctagttct tgtaaggttt cagcggttat
     3661 ttgctcaacg tgttcgattt cttgcggata gaagaatagt ttacccattt gaaaggttcg
     3721 gtctctcatc gcttttttca actcttcttg tttctttgta tcggacaaat agtcagacaa
     3781 agctaagtgg tcgtcaagtt catgttctgg ttgcggccat atgtaataat ccttgatatc
     3841 gactgttttg ctccactctt tcagtatcgc aagcaactgg ttatacgctg caatgctacc
     3901 atatcgttct tcgcttttat aatgttggta catcaaatag atttggtatt gtttttgatt
     3961 caacaaaact gctagacagg cattctcgtc ttgacgagat tcgcttcggt acgcgctcca
     4021 aaaatgactg cgtaaattcc agccattcgt ccagctttcg attttaggtt tgctcatgcc
     4081 gtacatatca ggcaaaagtg cagctgtctg gagctgaatc tctttccatt tttgccagtg
     4141 ttctttatat tctttcttga tttgttcaat cttatctgtt ggatggctct ctttgagctg
     4201 tttgaatgcg tagattggtc gatcaaacaa ctgataatct gattttccaa gttccattgt
     4261 ttcgcctctt tccgttatct tttgtattct acctgaattt tgcgatatgg acaaatagag
     4321 gttgtgaaaa agctgttctg catcaagtca taagaacagc caaacaaaaa actgcgatga
     4381 gcatcaccgc agttttattg aacttaaggt tgattgatca catctaaaag cgttgaaaat
     4441 aaaatggcac tagaagcagc tcctgggtcg atatgtccga ttgcacgctc tcctagatag
     4501 gaagctcgtc cttttttagc taccaagact ttggtgtgtt cttttgcctg gtcaatgatt
     4561 tcttttgtta aattccctgc cttcaatgcc tctgtgactg gcagccaaac atctaacatc
     4621 gttttatcgt cagcttctgc ctttcctcgg ctttgaatac ccgctgttcc ctgctcgatc
     4681 acttcgccta atttttcttg agaatcaata gaatcgacct cttttgtcgc tttcatcatg
     4741 ttcatgaatg cagatccgta taacggacca gaagccccac cgactttcga tatcatcgcc
     4801 atagagaata ctttgaatgt atcgctgatt gtttcaggat gatcggcttg aaaagcttct
     4861 tcataagctg aaacccctct tcccatgtta tttccatggt ctccatcgcc aatcggggta
     4921 tctagatcac tgagatattg tttgttctga ttgattgcct ctgcaaattg cgtgagccat
     4981 tcttggattt cttgaacggt tagtttcata ttatcaccct tttatcttga gattttttac
     5041 catgaaatcg tctgtacatt gctttctaaa gaatctttcc attgtgtctc cgtcaagtcg
     5101 atcagtgtta gagaaagacc ttgcatatct agtgaggtca taaaattacc gacttttcgg
     5161 aaaactacat tgacgcctct ttcttccaac agagctaaaa catcattcat gaacacgaac
     5221 tgttccatca aaggcgtccc gcccattccg ttgactagta cacctgcttc ttttggtaaa
     5281 ttcgagtaat catctaaaat cttagtaaca agttcctttg ccagtacttt agaaggctgc
     5341 atcttttctc gacgatagcc tggctcaccg tggataccaa caccatactc gatctcatct
     5401 tctcctagtt cgaatcctgg tttccctact tctggtacag ttgctgctcg aagcgctaga
     5461 ccgatcgtct tagttgcctg tacgaccttt tctcccagtt ctttcaactc agctagggaa
     5521 gcaccgtttc ttgctgcatc gcccacgatt ttgtgtacaa ggacagtacc tgcaactccg
     5581 cgttttccag cagtatacgt actattttca acggcgatat catcatctac gatcacactt
     5641 tctacttcaa tatcgtccat agcagctaat tcctttgcca tatcgaagtt caatgcatcc
     5701 cctgtataat tcttaacgat cagcaaaact ccttttccac tatccgcttc cttaatagcc
     5761 gtctgaatct gatctggagt tggagaagta aacacatcac caagcaccgc tgcacttaac
     5821 atcccttccc ctacaaaccc ggcatgggat ggttcatgtc cgcttcctcc accagaaacc
     5881 aaaccaactt gttccgcttt ctgattcttg gctacaacac gggaagattc tacacgatga
     5941 acaagttctg gatagctttt tactaatcct tccagcattt cttcgacaat attgcttgga
     6001 tcattcatga tttttttcaa tttattccca tcctttcttt ccggcatttt gtgcttctgt
     6061 taagatttgc tgagtatcat ctgttatacc ggcagtgatg gctgctgcaa aagctccttc
     6121 cactaaaggc gcatccacca gatgataacg ttgctgctgc tcttcttcca acatgtcttt
     6181 tgccagttcc gagttcaata ccgcgctacc gatatccgca aaaacaaaat aactagctgc
     6241 atcgcttgat tcattgactg cttctacgat tttcatcggg tctgatccga tctcgccatt
     6301 tattccgccg agagaaaaaa tttgcacctc ttcggatttt tgcatctgct caatcatttc
     6361 tttaatacca tctgttactt tttgactatg agaaataagc aaaatacttt ttttcacaag
     6421 aatcttcctt tcttttacat agttgctaac gattggtttc gctttcatta atgaacaatt
     6481 caagtatata ataaatttct aattttggga aaatatgtgt agtgcttctt gaagtttgtt
     6541 atactttaat taaaagagag gagtgatcga atgattacaa caacaacgaa cagtgtagag
     6601 ggaaaagccg tagtagctta taaagggatc gtttttggtg aggtcattac tgggatccat
     6661 gcatttaaag acttggaggc ggggttgcga aatatctttg gcggccgctc aaaaagctat
     6721 gaaaacgaac taatgggtgc aagagaagaa gcacttgccg aaatggccga acgtgcaaaa
     6781 gcattaggag ctgatgcgat cattggcgta aaaatggact atgaagtatt aggcagcgac
     6841 aatggcatgc tgatggtcac atgtagtgga acagctgtct ccacgagata agtaggggac
     6901 atctgtttta ataa
//
LOCUS       DAXLPC010000112         6904 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.113, whole genome shotgun sequence.
ACCESSION   DAXLPC010000112 DAXLPC010000000
VERSION     DAXLPC010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.113"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..173
                     /locus_tag="ACF3UE_002466"
     CDS             <1..173
                     /locus_tag="ACF3UE_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HFD3635827.1"
                     /translation="RNIFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLF
                     ATLLNYSIYFLN"
     gene            complement(281..1507)
                     /locus_tag="ACF3UE_002467"
     CDS             complement(281..1507)
                     /locus_tag="ACF3UE_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFD3635828.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(2261..2461)
                     /locus_tag="ACF3UE_002468"
     CDS             complement(2261..2461)
                     /locus_tag="ACF3UE_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFD3635829.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(2595..3203)
                     /locus_tag="ACF3UE_002469"
     CDS             complement(2595..3203)
                     /locus_tag="ACF3UE_002469"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFD3635830.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNAAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(3288..3758)
                     /locus_tag="ACF3UE_002470"
     CDS             complement(3288..3758)
                     /locus_tag="ACF3UE_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFD3635831.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(3806..4720)
                     /locus_tag="ACF3UE_002471"
     CDS             complement(3806..4720)
                     /locus_tag="ACF3UE_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFD3635832.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKNVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            4866..5669
                     /locus_tag="ACF3UE_002472"
     CDS             4866..5669
                     /locus_tag="ACF3UE_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFD3635833.1"
                     /translation="MTTKQLIISSFIRFKDLKETRNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKELR
                     SFLSKASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            5847..6794
                     /locus_tag="ACF3UE_002473"
     CDS             5847..6794
                     /locus_tag="ACF3UE_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFD3635834.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
BASE COUNT         2149 a         1368 c         1046 g         2341 t
ORIGIN      
        1 taagaaatat tttcattgca gcaatcgata ttacactttt agttattttc ttgtcagtgc
       61 ttatgtatca gttgtggcta catcatcgcc tggcaatgtg gctcatgatt ccttattatt
      121 tatgggtact attcgcaact ctattgaatt attcaattta ttttttaaac taagcgctaa
      181 aaagagacgt cctgtaattt aacacataga aaaagtgcca cctaagttag attttttgtc
      241 taatttaggt ggcactcttt attaaccaaa ctattttttt ctagtaccca cttgttgttc
      301 catactcatt attctggtca taaccataac cattttgttc ctgtccagcg taaggatcat
      361 aactttgagt atcttgactt ggtgtatagt actgacttgt atcttctgtt tgctgataat
      421 aggtattcgg atcttggtac tgatcatatg tgttttctga ataggaagaa taatcggtgt
      481 acccttcact attcgatcca tcaccgtttg tcgaatcgcc atcttccgaa tcatcaaaga
      541 acatcattga agcattctca tttttcaaat taggtaatgt atcgcttgtt tttatattta
      601 attgtttctt cagttcattt tggatcgaaa gaagatcatt ttttcctaaa atttgatagt
      661 agatatcatt gatcatttgt ccttcgcctt gcaactggtc ttgtttgatt gtttcaaacg
      721 caggggtgta gttcgtcgct acatcaagca tgtcatccca atctaagtcc gtcgtcacat
      781 tgttctcaac tgcttttaaa atttttctat aattgcttac gccatctaaa cttaaaactt
      841 tattgacgat tttcgtcact acttcccgct gacgacgttg tcgaccgata tcgccttctg
      901 gatcttcgtg tcgcattcga gaataggcta aacctttttc tccattcaat gtttgttcac
      961 ctactggtac atggacacca tccaaagtaa agtcaatttt attattcact ttgatgccac
     1021 cgaccgcatt gatcaaatct tccatgccat ccaaattgat cgttacataa tgatcaatag
     1081 gaatatcgag cagttgctca attgaatcca tggccatttc gacaccacca aatgcatagg
     1141 catgatttaa tttatctacc gttccataac ctacgatatt cgtataaata tctcggtcca
     1201 aactgatgat cgttgatttt ttttgtttcg gattaactgt tactaccatc atcgtatcag
     1261 aacgtccttg ttccgttctt cctaatccac cggtatctaa acctaatagc aaaaccgaaa
     1321 aaggttcttt gtcatcaatg cttactctct cagaacgttt ggaggatatt cgattagagt
     1381 ttttagaaat tttgtttact gtttggctcg cttctcccat aaatctgatt ccgtatgctg
     1441 ataatccggc aatcagcaaa acaaataccc ctaacaaggt taatagaact ttttgccatc
     1501 gcttcataat acacctctgt ttcacatttt ctaaaatatt gtctcatata actgttcaat
     1561 cagcaaattc actttttaat cataagaaaa ctttaaaaaa catttttgtg taacgattac
     1621 tattttttaa aatttctcaa aattcttaac tatcatacca taccgtgaaa aagatcgaaa
     1681 gaccgaatac acgcagttcg caatcgtttt atcttttttt acgtattttt tccagaaaaa
     1741 gcgaacaaca aggtattttc caaataatcg tgcagtaaaa tgatcgcaca tacctttccc
     1801 atctttttaa cagtctttgc ctaccgttca gattatcatt cgatttcacg aaaatttctt
     1861 cctatgactg gtccttttgt taaacccatc ttctattcgt tttatttcca gctcactgca
     1921 tggctcttaa aatgactcga actagtgatt tcattaccat catcttttaa tggatagata
     1981 tgctcctctt caaagtaaaa cgattttctt ttaaagtaat agaattgaca tggtaatgag
     2041 tatgtatact agtggtttca caaatggtct tttattcaac atccaaaaac tgaaatttct
     2101 ttaaaatcca ttactaacga agaaaatgtt ccttgcttga taattagtta ggacatgtca
     2161 agtgaacaaa tgcatttact tagccaaaaa atctaaaaac ttcataaata gacaaaaaga
     2221 cacgactctc taagaagtcg tgtctttatt caacaaatta ttataattta gtcacttcag
     2281 cagcttgagg tccgcgtgca ccttcaacaa tcgtgaattc tacttcttga ccttcttcta
     2341 ggctcttgaa gccgtctcct tgaattgctg agaaatgaac aaatacgtca tctccgccgt
     2401 ctactgtaat aaacccaaat cctttttcat tgttgaacca tttaaccgtt ccgtgttcca
     2461 taaatgtata gcctccaaaa aagttcttgc aagtaacctt gcaagaacat tatacccaat
     2521 ttagaaaacg ctagcaagct ttcgctcttt tattttccaa attattttta agactgatat
     2581 gacggaggaa atggttattt tgctgcttcg aaacgtttgt ttacttcatc ccaattaata
     2641 acattccaga atgctgcaat ataatctggt cggacatttt tatatttcaa ataataagca
     2701 tgttcccaaa cgtccaaacc tagaattggt gtctttcctt ccatcaatgg agaatcttga
     2761 tttgcagtag aggtaatagc taattttcca ttttccatta caagccaagc ccatccagaa
     2821 ccaaatcgtc cagcggctgc ttttttgaat tcttctttaa aagaagaaaa atcaccaaaa
     2881 gcttcattaa tcgcttcttt tatttctcct gtaggttcgc caccagcatt tggtgccatg
     2941 atttcccaga aaaatgaatg gttagcatgt ccgccaccat tgttacgtac agctgtcttg
     3001 atatctgttg gaatagcgtc catatcagat aataattctt ctattgtttt ttcgcctaat
     3061 tctgggtatt tctcaattgc tgcatttaaa ttcgtcacat aagtattgtg atgcttatca
     3121 tgatgcagat gcatcgtttc ttcgtcaata taaggttcca atgcgtcata tgcataaggt
     3181 agatctggta atgtgtaagt cataaaaaaa ttcctcctca atgttttctt tataatgtct
     3241 acattacaaa gagtaacaaa gagaaggaaa ttcttcaatt gttatgccta gtcgtctttt
     3301 tcactttgac ctacttcttc ttcaaaaacc tcagtttctt taaaaataaa caacttgctg
     3361 aaaatatagt tcgctaggat aacaataatt tgagtgatga ttttcgccac atactcattg
     3421 ctgttcataa cattgatcaa caataccatt gcccccatgt ccaatccgta agaaaggata
     3481 cggtagaaga agaacttacc gcattcaata agtgcatgtg taaaattcgg tgattttgaa
     3541 tggaataccc aaagtttgtt cgttacaaaa gcaaacaata cagaacaaaa ccacgaaata
     3601 gaattggata aggccatact taaatcaaaa tattggcgtg cgagagcaaa actaacaaaa
     3661 tttacaatcg tagccaaacc accaaaaaag agatagacta gtatctccca atatcctttt
     3721 gcttctaaat atccttttaa ctgtcgatac tgcttcatga gccaacctac cttattaaaa
     3781 attcttattt atcatactct atatttcaat aactttcatc tttatttaaa aaaattaatt
     3841 ttttttgatc ctttgccttt gtctctgctt ggatcgtcac atgtgtaata ccatatttta
     3901 attttaataa agaaattata cgaggatata tcttttcaat ctcgcttagt agctgatctt
     3961 caaaatcaat atgtccgtcg aaaataatta tcttttcgct atactgccaa atatggacat
     4021 gatgaacatt ctttacccca tcgattgctt caatttcttg ttccattttt tcatagtcaa
     4081 tagcaggtgc actttgtatc aaaatagcgg cagctttttt gatcaccatt atcgcttcta
     4141 tcaatatata tatcgaaatg atcagtgtaa taactggatc gatccagtag atatcgaaaa
     4201 aacggatcaa aattgctccg ataatcacac ttaccgaaga cagtgtatca cttaacaaat
     4261 gcaaataact agattttata ttcaaacttt catctgcttc ttgtcgtaat aataatactg
     4321 agaacaaatt cgcgagcaat ccaataactg ctactgttag catcaaatga ctatttatct
     4381 tttctggtga agtgaaccgc ttgaatgctt caacggttaa aaacaaggat aatatgatca
     4441 atatgaatga gttgatgaaa gcactcaata tttctaaacg ctggtagcca tacgtacgtt
     4501 ttttatttgc ttcttttcgg gccatttttt gtgccccgta agaaaaaata attgccaatg
     4561 tatcactaag gttatggaaa gcatctgaaa caagagacaa actccctgac ataatccctc
     4621 caataaattc tgataaagtg atcaccgcat tcaaaaccac tactccaaat agtttttttg
     4681 atgatctctg tggctgtgta ggcactattc cttcctccat tttatttata ttggatagtc
     4741 tttagacaag aataacattt ttttgatatt tcaccaatca ttcagatgtt tccctaaagc
     4801 acttgtattt cacttgatac ttcgctagaa ttgcaagtga tgacactact agatgaggag
     4861 tacttatgac aacaaaacaa ttaattatca gttcctttat acgattcaaa gacctaaagg
     4921 agacgagaaa tgtcccattt tggaaagcca ttgtctatct tttagttttg agtataatta
     4981 tggctttgcc aatctctttt caagtttttc aagtcttaaa caacattcaa ttggatgggc
     5041 aaaagattgc tactcgcatt cctgatttta caatccaaaa cgggcagctt caaaccgaag
     5101 aaaaagaagg attcatttac caaacaaact ccattatctt cacatttgat ccagagggaa
     5161 aacgaacaga acaggacatc tctactgatt tgatggggaa ttttgttagt gtcgggatgt
     5221 taaaaaacaa acttatcata gctcttccta atacaggcac gacttctgct ttgttgaaca
     5281 ataaccaatt agaacttccc tacaccaatg aatctttaaa aaacttaaca ggtaaggagc
     5341 tccgttcttt tttaagtaaa gcatctatac cactttggat aaaagtcctg acatttatat
     5401 tttctattta tcctagtttt ctgaatctgc tgatcacttt gctatttacc aacattgctg
     5461 cttttctcta tgcacgcttt cgactaacaa aagctacttt tcttgattgt ttaaaaacat
     5521 tgatctattc aatttcattg cctactataa ttgcaacaat cttgatggtc tttcttcctt
     5581 cttttgacac aagcgccttc attgcttttg caggaatctt tatttttgct caagctgtca
     5641 aaggatgggc aaaaatatcg atcaattaag aaataaagac aactcgttat ttctacttca
     5701 atagaccctt ttagaggttg tgacattttt ttgtcacagc ccctttttta tttgaaaaat
     5761 atttctttct caaaaaacaa gcaaggcgct tcaaagttct tcttgtatgc gctacactta
     5821 gagtaaagaa aggcgggaaa ttaactatgt cagaaagaat catttatgca gatcgtccat
     5881 ttcgtgatga atttatcgaa gaaatccata ctatagcgcc tggttatatc tttaaaacag
     5941 aattacaacc agaggatcta caaaatgtag agatcagttt gggctggaac tcagactacc
     6001 aagaaaaact attagcctct tctaccttga aatgggtcca atctatctca gctggtgttg
     6061 atcagctacc ccttgagact ttttcaaaga aacatatttt actttcaaat ggtagtggca
     6121 tccacagtga atcgattacg gagcatgtct taggaatcat ccttgggtat tctcgtggtc
     6181 tttttcaagc acaaaaagca cagagtgaca tgaaatggtt aggttcatcg gtccattacc
     6241 aatctatcca aggaaaaaaa atactaatca ttggaactgg ccatattgga aaaatgattg
     6301 caaaaaaatg caaagcatta gacatgaact gctatggaat caatacatcc ggtcatccag
     6361 cagaaggaat ggaaaagact ttttctttaa atcaactaaa ggaagttctt cctgaagtag
     6421 atttcgtagt caatatctta cctctaacgg aggaaacaac tgggctcttt gatcagcata
     6481 tgtttgaaca ctttgatcca aaatctgtat tcatcaatgt tggccgtggt gcttctgtta
     6541 agacacaaga tctggtgcag gctttaaata accagcaact ttcctttgca gcattagacg
     6601 tttttgagga agagcctctt ccacaagatc atcctctttg gaaaatggac aatgtactga
     6661 ttacttccca cattgcaggt ttgacacctg attttcaaaa gaaattaatg gctatttttt
     6721 taaccaatct gaaaagctac tttgccaccc atgagcttca aaccaatcaa gtaaaattgt
     6781 ctgcaggata ttaatagctg aaaacaatat tttcaaaaga acaaagagaa ggtgacaaaa
     6841 ctggctctat aatttatggg actgatgaat cagaattgat tcttcagccc catttttatt
     6901 ttag
//
LOCUS       DAXLPC010000113         6603 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.114, whole genome shotgun sequence.
ACCESSION   DAXLPC010000113 DAXLPC010000000
VERSION     DAXLPC010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.114"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            374..973
                     /locus_tag="ACF3UE_002474"
     CDS             374..973
                     /locus_tag="ACF3UE_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3635835.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLSDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQVHDFSKYLFPSRKLADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            1022..1492
                     /locus_tag="ACF3UE_002475"
                     /pseudo
     CDS             1022..1492
                     /locus_tag="ACF3UE_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405176.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1706..1969
                     /locus_tag="ACF3UE_002476"
     CDS             1706..1969
                     /locus_tag="ACF3UE_002476"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635836.1"
                     /translation="MKQIQNDLYGNIEKEYFDSQMFQQNSSPYYSEERFFQLMEQEEE
                     KRLLQLMKEMEEQQVAEEIEEKRFIKLIEEQMEIESLREQEEE"
     gene            2117..4219
                     /locus_tag="ACF3UE_002477"
     CDS             2117..4219
                     /locus_tag="ACF3UE_002477"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000921212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HFD3635837.1"
                     /translation="MMTTQDLMDKYEVSRQTVNNWVRKNEIPAPTVKKGHQNAWTFSQ
                     AELIDKKLKHSHSEQLELFKTESTPLHINNRRYLGSKQKILDFINDVVSEHTKNVKSV
                     ADVFGGTGVVANLFNKQGKKVIVNDILTSNYISYETWFGNMPVDEKKIQFKIEELNSL
                     EGIHGYVDKNFGNKYFSVENAQKIDAVREKIETYNDLNEREKAFLLTSLLYAMDKVAN
                     TVGHFDAYRKKMDTFKPIYLRVPEFNKNVGNEIYNEDANQLVRKIKTDLVYIDTPYNS
                     RGYESAYHVLENVMEWKKPDVEGVAMKAVNRSEKSSDYTKSKAPQAFDDLIQNINARY
                     ILVSYNNMAKKGNSRSNAKISNEEIIATLKKRGQVEVFSIDFNAFTTGKSNIENHKEL
                     LYLCTVDDEIIQSPLNYTGGKQKLIPQLRPYFPSRYTRLIDLFSGGGSVTANLAKNGQ
                     AESYLMNDVENHVINFFEYISTIDIDDFINQAEMKISEYGLSNTKKNGYEFYSANSAS
                     GLGAYNKEKFLKLRKDYNNSPSPLLFYLLVVFGFNNQIRFNSKGEYNLPVGKRDFNKK
                     MEEKLRKFVKVIQDSPIEYSTKDFREVSIDTGDFIYADPPYLITTAAYNENGGWSEKD
                     EKDLYDYLDKANENNIKFALSNVIIHNGRENEILKSWASKYNLYVLNYNYNNSNYQSK
                     AKQSETVEVLVTNYERDI"
     gene            4219..6174
                     /locus_tag="ACF3UE_002478"
     CDS             4219..6174
                     /locus_tag="ACF3UE_002478"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF021040.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlwI family type II restriction endonuclease"
                     /protein_id="HFD3635838.1"
                     /translation="MKLTNTAETFNLGDTSFRRKTLIDDYKTLLPYLQETNLEFNEWN
                     NVAQAEFYEKILTKTDLFSRNTDEDFAKRGRTLTNALVKIGLTNSKRKLSRVANSWIN
                     ENTLSANDVERSLGIDANNLLFTRQLLKLRVYDSNKMNYFYPFRVALGLVIKYQNIPQ
                     QDFLTLIHLIQPSFDNRKIKDIINDYHSVNDNNEIFSEFLDRNFPENTSELTADELFS
                     KKPLNRKEFDSLFVNRKSSATQGIYFEFVNKLLAFKSNKNVENLDALLELNSNDKLTK
                     AFGFGKAIFAKTNFMKSKNIQDFLDENVDNDLLSENNTLIYNQFVLSKKDDIVREYRD
                     MTKRTFNLSGLLDFNTGLVNATNQDVLSIIFSSMSFSGTENYADYEENLSYSFYQEST
                     ITEVLDLDESAILSEIKAFLGIENTSQIESVVLTQKEDKFRKFISKTFPREKIIEILP
                     LFSPRDDKKIKSEVSESATVPTIYEYIVAIAWFYISKEEFFITKSLNLTLDGEMRPLS
                     HAAGGAGDIVIDYENLTLMLEVTLMNAQAQKRGEWEPVLRHATNLTVDNFDKNVITLF
                     IADELDDNTVNIWRAVASVPLRSSNKDEIADLVKIFPLENRELLHMLKNNLDERKLLK
                     AIDESYEELAGNFDLSWRDKIFVEANM"
BASE COUNT         2398 a          955 c         1235 g         2015 t
ORIGIN      
        1 gattcatcgt cattcctcct gctatctttt tctattattc taccttattt gatagtagat
       61 ttaaaacttt gcaacagaac cgttaattat atagactgaa aattttgaat tttcagaata
      121 gaacaactta aaagtactga caaaattttt taaaggggca atattaatgt tctgagataa
      181 tcaaatctta ccgaaaatct caaaagtcca atgtgacaca agctgattct gtcacattcg
      241 ttaaaatcgc tccatcctta gaggctctaa gaggaaatca cttttctttt agggcctttt
      301 ttctatagct tgtttaaatg tgacttatta tctgttataa tcatattaag taacatttga
      361 gaggggacta aaaatgaaga gcgtggaacc gattcgcgac aaaaaaaaga tcgatgccat
      421 gaaggccatt ttggcttccg gaaaatatgg gcaacgaaat ttggtgcttt tttcaatcgg
      481 gatcaataca gcctatcgaa tctccgattt aaggcagttg aaattaagtg atgtgttaga
      541 aatttcccgt gggcgggtga ttgtcaaaga acgtctggcc atgaaggaac aaaaaacggc
      601 caaacataat tcggtcttca tttcaaacaa attacgaaaa gtgattctcg attatgtcca
      661 atccgaattt cctgagcagc tgcaagtaca tgacttcagc aaatatttgt ttccaagtcg
      721 aaaattagca gatacgcctt tgacccgaca aagcctttgg cggatcattc atgaagcagg
      781 aacagcggtt ggtttaaaag aaattggtcc ccattcgatg cgcaagacct tcggctattt
      841 tttgtacaag caagggacca aaacagagat cattcagtcg ctgctcaacc attcttcgca
      901 acgggagacc ttacgctata ttgggatcac ccaggaagat aaagataccg cagtaaagag
      961 tttggatctg tgacagaata atgccctata taatagaaga aaaaattcaa gaggggagaa
     1021 gatgaacgaa gaaaagcgtc cgaaatttcc tgataaatac cacttatctc gcaaagagtc
     1081 tgtgtattta ttgaagaaaa acattgtgga actggtgtat aatgcgggaa aatttgaagg
     1141 gttaaataca acgctattac aaacagaaga gattatcaag tataatcgag ctaataatat
     1201 ggcggtagat gatgtcctga ccgtcgttaa cttaaaaaga ggctttgaaa tgcttttaaa
     1261 cgacttacag gagcccctaa tagagacaag taagcggatt aatcggatcg ttgcagcaga
     1321 ggatgcgctt ttttccggtg aaatacgaac tggtggggta gaagtatcga cgattcaagg
     1381 aagatatgtg ccaccaatgt taactgaaga cgaggtaaac aatcaatatg gtgagataat
     1441 gaataaagag atatcagata cggaaaaagc cctgcgactg tttctattca tttaatgcaa
     1501 taggagcggg tatttgtaat gcttcccata gtgccacccc atttttgaaa tcaatttccc
     1561 acgtttcttc gttctcgcca ttctttggga gaagctcaag agatggcgga gtaaaatcaa
     1621 attcgctttt cattatatta attgtctaac ttaatttgac aattaatatt atttatacag
     1681 cacaagtgag aaatatattg aacagttgaa acaaatacaa aacgatttgt acggtaacat
     1741 tgagaaagaa tattttgata gtcaaatgtt ccaacaaaat tctagcccct attattctga
     1801 agaacgtttt tttcaattaa tggaacagga ggaagaaaaa agactacttc aattaatgaa
     1861 agaaatggaa gaacaacaag tagcggaaga aatagaagag aaacggttta ttaaattaat
     1921 agaagagcaa atggaaatag aaagtttaag agaacaagaa gaagagtaag ttctgcgttt
     1981 gttagaaaca taatatcttt gaaaacaatt tagacaaacg acaggaaatg gtaatttgaa
     2041 aactaaacat tgataattac ttattgcact taatatggta gaattgcatt aactgtaaag
     2101 agagggtgat gcctaaatga tgacaacaca agatttaatg gacaagtacg aagtatcacg
     2161 acaaactgta aacaattggg ttcggaaaaa cgaaattcct gcacccacag taaaaaaagg
     2221 gcatcagaat gcttggacat ttagtcaagc ggaacttatt gacaaaaaat tgaagcatag
     2281 tcacagcgaa caattggagt tgtttaaaac tgaatcgact cctcttcata tcaataatag
     2341 aagatattta ggcagtaaac agaaaatact agattttatc aatgatgttg tttcggaaca
     2401 caccaaaaat gttaagtcag ttgctgatgt ttttggtgga acaggtgttg ttgctaattt
     2461 atttaacaag caaggcaaaa aagtcatagt taacgatatt cttacaagca actacatttc
     2521 ttatgaaaca tggttcggga atatgcccgt agatgaaaaa aagattcagt tcaaaattga
     2581 agaactgaat tctcttgaag gtatacatgg atatgttgat aaaaattttg gtaataaata
     2641 tttttcagtt gaaaacgcac aaaaaattga tgcagtccgt gaaaagatcg agacttacaa
     2701 cgatttaaac gaacgtgaga aagcattttt gttaacgtct ttgctatatg ctatggataa
     2761 ggtggctaac acagtaggac attttgatgc atatcggaaa aaaatggata cctttaaacc
     2821 tatttattta cgagttcccg aattcaataa aaatgttgga aatgaaattt acaatgaaga
     2881 tgctaatcag ctagttagaa aaattaaaac agaccttgtt tacattgata caccttataa
     2941 ttctcggggc tatgaaagtg cttatcatgt tttagaaaac gttatggaat ggaaaaagcc
     3001 ggacgttgag ggagtggcaa tgaaagcggt caaccgctct gaaaaatctt cggactatac
     3061 taaatctaaa gcaccccaag catttgatga tttgattcaa aatattaacg ctcgatatat
     3121 tttagtttcg tacaataata tggcgaaaaa aggaaattca cgttcaaacg caaagatttc
     3181 aaatgaagaa attattgcca cattgaagaa acgtgggcag gtagaagttt tttcaattga
     3241 ttttaatgct tttacaacgg gcaagtcgaa tatagaaaat cataaagaat tactgtatct
     3301 ttgcacagtt gatgatgaaa taattcaatc gccactgaat tatacgggcg ggaaacaaaa
     3361 attgattcca caattacgac catattttcc ttcaaggtat acacgattga ttgacttatt
     3421 ttctggtggt ggtagcgtta ctgcaaatct ggcaaaaaat ggacaagcag aaagttatct
     3481 tatgaatgat gttgaaaatc atgtgattaa tttttttgag tatatttcaa ctattgatat
     3541 agatgatttc attaaccaag cggaaatgaa aataagtgaa tatgggttat ctaatacgaa
     3601 aaaaaatgga tatgaattct attctgcgaa tagtgctagt ggtttaggtg catacaataa
     3661 agaaaaattt ctgaagctaa ggaaagatta taataattca ccgtcaccat tgctatttta
     3721 cttgttagtt gttttcggtt ttaataatca gattcgcttt aattcaaagg gtgaatataa
     3781 tcttccagtt ggtaaacgag actttaacaa aaagatggag gaaaaattac gtaagtttgt
     3841 aaaagtaata caggactcac caattgaata ttccaccaaa gatttccgag aagtgagtat
     3901 agacacagga gatttcatct atgctgatcc gccgtatctt attacgacgg cagcttacaa
     3961 tgaaaatggt ggttggtctg aaaaagatga aaaagactta tacgattatc tagataaagc
     4021 aaatgaaaat aatattaagt ttgctctttc aaatgtgata attcataacg gaagagaaaa
     4081 tgaaatcctt aaaagttggg cttcaaaata taatttgtac gtcttaaact ataattacaa
     4141 taatagcaac tatcagtcca aggctaaaca aagtgaaaca gttgaagttt tagtcacaaa
     4201 ttacgagagg gatatttaat gaagcttaca aataccgcag aaacatttaa tctaggtgac
     4261 acaagtttta gaagaaaaac attaattgac gactataaaa ctttgttgcc ttatcttcaa
     4321 gaaacaaatc tagaattcaa tgaatggaat aatgtcgcgc aagcagaatt ttacgaaaaa
     4381 attttgacaa aaacagattt attttctagg aatactgatg aggattttgc aaaacgtggg
     4441 agaaccttaa ccaatgcctt agttaaaatt gggctaacaa attcaaaaag gaaactttca
     4501 agagttgcta atagttggat aaatgaaaat acgcttagtg caaatgatgt tgaacgttca
     4561 ctaggaattg atgcgaataa tttattattc actcgtcagc tgttaaaact acgtgtttat
     4621 gattcaaata agatgaatta tttttatcca tttcgtgtcg cattgggatt ggtgataaag
     4681 tatcaaaata tcccacaaca agattttcta acactaattc atttaattca gccgtcattt
     4741 gataatagga aaataaaaga catcattaac gactatcaca gtgttaatga taacaatgaa
     4801 attttttcgg aatttttgga tagaaatttt ccagagaata caagtgaatt gactgctgat
     4861 gaactttttt caaaaaaacc attaaataga aaagaatttg attcgctgtt cgtgaataga
     4921 aaatcttcag ctacgcaagg aatatatttt gaatttgtaa ataagttgtt ggcgtttaaa
     4981 tctaacaaaa atgttgaaaa tttagatgct ttgcttgaat tgaattctaa cgataaatta
     5041 acaaaggcat ttggatttgg aaaagctatt tttgctaaaa cgaattttat gaaatctaaa
     5101 aatatccaag attttttaga tgaaaacgta gataatgatt tgctgtcaga aaataatacg
     5161 ttgatttaca atcaatttgt actttctaaa aaagatgata tcgttcgtga gtatcgagat
     5221 atgacaaaac gaacattcaa tttatcggga ttattagact tcaatactgg actagtcaat
     5281 gctaccaatc aagatgttct ttcgataata tttagttcta tgagtttctc gggaactgaa
     5341 aactatgctg attatgaaga aaacttgagt tactcattct atcaagaatc tacaataact
     5401 gaggtattgg atttagatga atctgctatt ttgtcggaaa ttaaagcatt tcttggaatt
     5461 gaaaatactt cacaaatcga aagtgttgtt ttaacgcaaa aagaagataa atttagaaaa
     5521 tttatctcaa aaacatttcc tcgagaaaaa attattgaaa tcttaccgct attttcaccg
     5581 agagatgata aaaaaattaa atcagaagta tcagaatcgg caacggttcc aacaatttat
     5641 gaatatattg ttgctattgc atggttttat atttctaaag aagaattttt tattacaaag
     5701 agtttgaatt taaccttaga cggtgaaatg cgtccgttat cacatgcagc tggtggtgct
     5761 ggtgatattg tcattgatta tgaaaacttg acattaatgc ttgaagttac tttgatgaat
     5821 gcccaagctc aaaaacgtgg agaatgggag ccagtattac gacatgcaac aaatttgacg
     5881 gtagacaact ttgataagaa tgtcattact ttatttattg ctgatgaact ggacgataat
     5941 actgtaaata tttggcgagc agttgcaagt gtacctctac ggtcatcaaa taaagatgaa
     6001 attgcagatt tagtaaagat tttccctctg gagaatcgag aactacttca tatgctgaaa
     6061 aacaatctcg atgaacgaaa actattaaaa gcaattgatg aatcatacga agaacttgcg
     6121 ggcaattttg acttaagttg gcgagataaa atttttgttg aagctaatat gtaaaaatgt
     6181 agtagtttcg atttaaacgg gaatgttttt tagtcaatgg aaaatatcac ttaatggtgt
     6241 gaacttatgg taaaagctag ctcaattcgt tttatttagg gttaaaattc acaccattca
     6301 aatgatatta gttgaaatta gatgaagttt tgttatttgc aatcgcccaa aagatttgat
     6361 aataaaagct tttgaaagtt attcaattag gcgttgttca agccaggtct taaaggcgct
     6421 cgtcgttcac tacagttctc aacgttaata tcgttgctat ttcaacgttt acagcactct
     6481 ttggattatt tcaaagagtg tttttttgta tttttataga ggtatttaga taagtttgtg
     6541 gaggtttgtt gcgctttatt ttgctatcca ggagttcatt attttaaaag cttaaataat
     6601 aag
//
LOCUS       DAXLPC010000114         6559 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.115, whole genome shotgun sequence.
ACCESSION   DAXLPC010000114 DAXLPC010000000
VERSION     DAXLPC010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6559
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.115"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            38..126
                     /locus_tag="ACF3UE_002479"
     tRNA            38..126
                     /locus_tag="ACF3UE_002479"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:72..74,aa:Ser,seq:gga)
     gene            141..212
                     /locus_tag="ACF3UE_002480"
     tRNA            141..212
                     /locus_tag="ACF3UE_002480"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:174..176,aa:Glu,seq:ttc)
     gene            228..300
                     /locus_tag="ACF3UE_002481"
     tRNA            228..300
                     /locus_tag="ACF3UE_002481"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:261..263,aa:Val,seq:tac)
     gene            310..382
                     /locus_tag="ACF3UE_002482"
     tRNA            310..382
                     /locus_tag="ACF3UE_002482"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:343..345,aa:Asp,seq:gtc)
     gene            418..493
                     /locus_tag="ACF3UE_002483"
     tRNA            418..493
                     /locus_tag="ACF3UE_002483"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:451..453,aa:Phe,seq:gaa)
     gene            495..575
                     /locus_tag="ACF3UE_002484"
     tRNA            495..575
                     /locus_tag="ACF3UE_002484"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:529..531,aa:Tyr,seq:gta)
     gene            582..655
                     /locus_tag="ACF3UE_002485"
     tRNA            582..655
                     /locus_tag="ACF3UE_002485"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:614..616,aa:Trp,seq:cca)
     gene            658..730
                     /locus_tag="ACF3UE_002486"
     tRNA            658..730
                     /locus_tag="ACF3UE_002486"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:691..693,aa:His,seq:gtg)
     gene            742..813
                     /locus_tag="ACF3UE_002487"
     tRNA            742..813
                     /locus_tag="ACF3UE_002487"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Gln,seq:ttg)
     gene            859..929
                     /locus_tag="ACF3UE_002488"
     tRNA            859..929
                     /locus_tag="ACF3UE_002488"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:891..893,aa:Cys,seq:gca)
     gene            950..1034
                     /locus_tag="ACF3UE_002489"
     tRNA            950..1034
                     /locus_tag="ACF3UE_002489"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:984..986,aa:Leu,seq:caa)
     gene            1096..1168
                     /locus_tag="ACF3UE_002490"
     tRNA            1096..1168
                     /locus_tag="ACF3UE_002490"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1129..1131,aa:His,seq:gtg)
     gene            1178..1249
                     /locus_tag="ACF3UE_002491"
     tRNA            1178..1249
                     /locus_tag="ACF3UE_002491"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1210..1212,aa:Gln,seq:ttg)
     gene            1267..1351
                     /locus_tag="ACF3UE_002492"
     tRNA            1267..1351
                     /locus_tag="ACF3UE_002492"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1301..1303,aa:Leu,seq:caa)
     gene            1606..2481
                     /locus_tag="ACF3UE_002493"
     CDS             1606..2481
                     /locus_tag="ACF3UE_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFD3635839.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            2585..3349
                     /locus_tag="ACF3UE_002494"
     CDS             2585..3349
                     /locus_tag="ACF3UE_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFD3635840.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            3336..4778
                     /locus_tag="ACF3UE_002495"
     CDS             3336..4778
                     /locus_tag="ACF3UE_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3635841.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            4789..6119
                     /locus_tag="ACF3UE_002496"
                     /pseudo
     CDS             4789..6119
                     /locus_tag="ACF3UE_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            6132..>6559
                     /locus_tag="ACF3UE_002497"
     CDS             6132..>6559
                     /locus_tag="ACF3UE_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFD3635842.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEV"
BASE COUNT         2064 a         1083 c         1452 g         1960 t
ORIGIN      
        1 ctcattttga gaaagagtat tgagcttctt tcactctgga gagttgtccg agaggccgaa
       61 ggagcatgat tggaaatcat gtagatggtg caaactgtct caagggttcg aatcccttac
      121 tctccgtagc aaatttacct ggcccgttgg tcaagcggtt aagacaccgc cctttcacgg
      181 cggtaacacg ggttcgaatc ccgtacgggt cattttaatt gaatgttgga ggtttagctc
      241 agctgggaga gcatctgcct tacaagcaga gggtcagcgg ttcgatcccg ttaacctcca
      301 taatgaactg gttccgtggt gtaggggtta acatgcctgc ctgtcacgca ggagatcgcg
      361 ggttcgattc ccgtcggaac cgtcgttctt gttattcaat taataatttt aaaatatggc
      421 gcggtagctc agttggtaga gcaacggatt gaagctccgt gtgtcggcag ttcgattctg
      481 tcccgcgcca ccatggagga gtagcgaagt ggctaaacgc gacggactgt aaatccgttc
      541 cttagggttc agtggttcga atccactctc ctccatttta taggggcata gtttaaaggt
      601 agaacagcgg tctccaaaac cgttagtgtg ggttcaattc ctgctgcccc tgccatggcg
      661 aatgtggcga agtggttaac gcaccggatt gtggctccgg cattcgtggg ttcgattccc
      721 atcattcgcc ctttttattc ttggggtata gccaagcggt aaggcaaggg actttgactc
      781 cctcatgcgt tggttcgaat ccagctaccc cagtttctat aatttattct ttattttgta
      841 gattgataat agtataatgg cggtatagcc aagtggtaag gcagaggtct gcaaaacctt
      901 catcaccggt tcaaatccgg ttaccgcctt agtactaata aatcaacttg ccggcgtggc
      961 ggaattggca gacgcgctgg actcaaaatc cagtgcccgt tgagggcgtg ccggttcgac
     1021 cccggccgcc ggtattgact aagatgtctt catcttagtt ttttattgag aaattaaata
     1081 acatctttta tgatggcgaa tgtggcgaag tggttaacgc accggattgt ggctccggca
     1141 ttcgtgggtt cgattcccat cattcgccct ttattcttgg ggtatagcca agcggtaagg
     1201 caagggactt tgactccctc atgcgttggt tcgaatccag ctaccccagt tattattttt
     1261 aaatttgccg gcgtggcgga attggcagac gcgctggact caaaatccag tgtccgttga
     1321 ggacgtgccg gttcgacccc ggccgccggt ataattatca atatagcaac tttcttatag
     1381 agagttgcta tatttttttt gtttttatgt aattacctcc aaatcaattc gatacaagta
     1441 ttatcataaa acgagtaaaa aagatattga taacgctttt attatgtgtt aaactatttt
     1501 tgtaaattat gtagggtgct actattcaat taggcacgac ctaagaaagg gttctttctt
     1561 aggtcgtttt ttgtctttaa aaattgtttg gagacaaaaa tatgtatgaa ggagtctgca
     1621 agttgttttg ttttatcata tagtggaggt gaattaacgg tgtatgtgat gaaaaagctg
     1681 aatcataatg ctgtattgat cgatgacgat ggaatagaaa aaattgcgat ggggaaaggg
     1741 attggctttt ctgctaaagt gagtaagcca tttgatgttg aggatgctga caaattattt
     1801 gtattagatt ctaaagaaaa gatcaaacga ttcagtgaga tagtctcgca gattccaatc
     1861 gaatttatgg attttgcgga agaagtgatt gaactgataa cagctaggat ctcctctcca
     1921 ttagattcaa atatctatat tacattgaca gatcatattt attttgctat tcaacgaaaa
     1981 agagaagata gagatgtcac agcaattatg ttgccagaaa tgagattcct ttatccaaat
     2041 gaatatgata tagcaataga agtggtcgag cgaatcaatc atcgatatca aaccgagtta
     2101 gggtcaaatg aagtaggatt catcactatg catatcatta atgctgagct aggagagcct
     2161 aatagtttaa agagcttaaa aatagtagaa atgacgacca cgattttgtc ccatctagaa
     2221 aaatcctatt caaacgttta tgataaagaa tcactgactt atcatcgctt aatggttcat
     2281 atcaaattcc tggttaaacg cttgatttat caggaagaaa cgccagtaga aaatattggt
     2341 ttttttactg aaacatttaa acatagcaaa gcgtattgta cagcactaaa gattaaagat
     2401 atcatcgaac agcaatttca acttgccatt caagaaaatg aaatcatcta tttggcaatt
     2461 catctagcac gaatctatta aaataagggc gtaactatct ataggcgcaa ccaaatgaca
     2521 catagtaaat ggactatgat tatttggttg cgcctatttt agtagaaaaa agaaggagaa
     2581 tgaaatggga aaagtgattt ttaattcgga tgattttggc tatagccatg gtgtgaatta
     2641 tgggattatg gatgcttatc agcgaggaat tttgacatca actacattga tggcaaatat
     2701 gccgggtttc gagcacgctg tgaaactaag aaaggaaatg cctaggctag gtgtaggagt
     2761 ccatttaaca ttgacgtgtg gcaaaccact tctcaaaact gtcgatactc ttatcgaaag
     2821 cggagagttc agatccttat cttattatca gcatccattt aacattgaca aagatcaact
     2881 gtatcaggaa tggaatgctc agattcaaaa aatttatcat gcggggatca taccaactca
     2941 tttagacagt catcatcata ctcatacttt ggatgaaaac caggaggtag ttgttacatt
     3001 agcaaaaaaa tatgatttgc cggttcggag caactttgaa cgaaaagatg aagttcgtca
     3061 tgtcgattat tttgagcctt gtttcgatgt cgtaggagaa actgatgaaa aaaaacgaca
     3121 aatcaatacg agtgtggaag aatatttggc aagtttactc atgatattga gagaagataa
     3181 aacgatcgaa gtcatgtgtc acgcagcgta tttggatcag gaattgttaa atggttcaag
     3241 ttttgtgtat cctcgtactc accaagtcga atttttaatt cattcagcat ttgctcaaaa
     3301 agtgaaaaat gatcctttga ttgagttagt aacatatgag gatatttaat agaggaggaa
     3361 taaaaatgaa tgttaaatca aatgtgcaga agcttggaag agcgatgcta cttccagttg
     3421 cagcgatgcc attagcggga ttgatcatgc gtttatcagc tgatgatatg ctgaacatcc
     3481 cagtaattgg tgcagctgga aatgccgttt ttggaaactt ggatatctta tttgctatag
     3541 gagttgcaat cggttttgtc aaaaataagg acaaaggaat acctgcactt actggttttt
     3601 tagcgattgc taccttgaaa aaaggcttag aaatcatgga cccagaagtg aatatgggga
     3661 tttttggtgg aattatttcc ggtttagtag cggcatggac gtataatcgc tttaaagaac
     3721 aaaaattacc agtagttttt tcttattttg cgggcgaaaa attcccattg actatggtga
     3781 tgattctaca aacaatcgca gctatttttt tgggctttat ctggccgctc atccaaattg
     3841 ggattgataa ttttgcaaaa ctgctcgttg atatgggggc attaggtgtg gggatattta
     3901 tgtttttgaa tcgtttgctg atcccctttg gactgcacca tgtgttgaat acgtatattt
     3961 attacgattt aggaagctat acatctccta gcaaggaagt tttcagagga gagatgacac
     4021 gctttatcaa cggagatcct caggctggac tgtttttatc aggttttttt gtagtaatga
     4081 tgtttggtat accagctata tgtctagcta tctataaagc agcttataaa gaaaataaag
     4141 agatggtcaa aggaatcatg ggaagcggtg caggaacttc atttattgca aatatcactg
     4201 agcctgttga atttagtttc atgtttcttt ctcctatgtt gtacgtgatc catgcacttt
     4261 ttgccggttt agcagggatt gtctgttact tattcaatat acgaattggt tttacattcg
     4321 gagcatgtat tgttgattat ctcatcaatt ttcgaatcgc taccaatgct attttgattc
     4381 ttccaatcgg aattttcttt tttgccttgt attacgttac tttttattat ttgatcaata
     4441 agagaaacat tcagacatta ggacgtgaag ctaaggcaga gtttggcaat gaagtaacct
     4501 tagaagaaac agagttaggg ttagcaagta aaaattatga atatatggca acaaaaatgc
     4561 tacaagcgtt tggaggaaaa gccaatatcc tggatgtcta tagttgtaat acacgcctac
     4621 gggtagaggt agtggatccc accatggtcg aggaacagcg aatcaagcaa ttagggataa
     4681 gcgggatcat taaaccaact gaaaaaaatt atcaaattat catcggctta gaagtgactt
     4741 atgttatggc agaattcaat aaattattag aagaatagaa aggaaaagat gatgatgaaa
     4801 aaacagatta tcactatagc tggaggcggg agtacgtata caccaggaat cgttcaagcc
     4861 attttgaaca atgaaaaacg gttgccatta tctgaaatac gtttatatga tattgatgaa
     4921 gaaagaaata tggatatgta cttgattgtt aaatttatgc tgaaaaaaaa ggtttttcaa
     4981 atattcgcat tcgtgcaacg gatgatccaa agcttgcttt tacaggatgc gattttgttt
     5041 tctcacaaat tcgtgttgga ggattggaga tgcgagaaaa ggacgaaaag attccactta
     5101 aacatggatt agtaggacag gaaacgtgtg gactcggagg atttgcttat gggatgcgct
     5161 caatcaaagg tttattggaa attgtcgatc atatacaaga ctatgccccc aaagcatgga
     5221 ttttgaatta tacaaatcca gagtcgatcg tttctgaagc tgttcgtcgt aaatatccga
     5281 atgtaaaaat gattaatgcc tgtgatatga ctatttcaat tgaagaaacg attgcagtga
     5341 attacggtta tgatcgtaag aattggatcg ttacgtatta tggtttaaac cactttggct
     5401 ggtatacatc gatttatgat aaagaattgc aacgagaaat tatgccagag attattgaaa
     5461 aactaataac aaaagaaatg caagtcgccg attttaatat aggagacaaa acttggcaaa
     5521 aaacctttca aatgatgtca gtcatcacga aaaattttcc aagtaatatc ccgaataatt
     5581 acttagagta ttacttatat cctgatatgg tcgttgagca tactgacaaa gagtatacac
     5641 gtgctaatat ggtcatggat ggacgagaga aaaataccaa agaaatggct gataaaatac
     5701 gccgcggtat tgtggaagaa gtattgaact ttaattttgg ggagcatgga caatatatcg
     5761 tcgatatagc tatttccttg ttgaatgatg atcgtcgtcg ctttatgcta atcgttccta
     5821 atcaaggggc gattccgaat ctacggtcag atgcagttgt tgaaataccg gcatatgttg
     5881 gtgcaactgg tgtggagaca attacactaa gaaaaccaat cagtgatttt cataaaggat
     5941 tgatggaggc acaagttgca gcagagaagt tactagtaga tgcttacttt gaaggttctt
     6001 atcaaaaagc tttacaagca tttacattga atcaaaccgt accaaatgcc agagtcgcaa
     6061 aaaaaatact agatgaaatg atcaaagtaa acaaaaaata ttggccagca ttaaagtaga
     6121 ggtgataaaa agtgcatttc tttaaaacaa gaaacattct aaaagctgta gctagtggtc
     6181 aaattattcc attaacagca gtaaaagacg aggtcttttc ttcaaaaatg ataggagttg
     6241 gatacgctat aacgaatcat gatggatata tccatgcgcc agttaaagga ataatcgata
     6301 atatatttcc tacccgacat gccataacga tcgaaagtga atctggcaga aaaatactga
     6361 tccatatggg tttagataca gttgaactcg aaggaagtcc gtttcagata cgggttgaaa
     6421 gtaaccagga ggtaaaagaa gggacactgt tagctattat agatttgaag aagttggagc
     6481 aagcacaaaa agatacggtg atcattgtag tttctccagg catttttgaa ggaaatttat
     6541 taaaacaaaa ccaagaagt
//
LOCUS       DAXLPC010000115         6533 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.116, whole genome shotgun sequence.
ACCESSION   DAXLPC010000115 DAXLPC010000000
VERSION     DAXLPC010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.116"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            185..1183
                     /locus_tag="ACF3UE_002498"
     CDS             185..1183
                     /locus_tag="ACF3UE_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFD3635843.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="ACF3UE_002499"
     CDS             1295..1804
                     /locus_tag="ACF3UE_002499"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFD3635844.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="ACF3UE_002500"
     CDS             complement(1834..2493)
                     /locus_tag="ACF3UE_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFD3635845.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="ACF3UE_002501"
     CDS             complement(2495..3259)
                     /locus_tag="ACF3UE_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFD3635846.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="ACF3UE_002502"
     CDS             complement(3267..3944)
                     /locus_tag="ACF3UE_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFD3635847.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="ACF3UE_002503"
     CDS             complement(3981..5366)
                     /locus_tag="ACF3UE_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFD3635848.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="ACF3UE_002504"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACF3UE_002504"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="ACF3UE_002505"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="ACF3UE_002505"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFD3635849.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..>6533
                     /locus_tag="ACF3UE_002506"
     CDS             6305..>6533
                     /locus_tag="ACF3UE_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HFD3635850.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCV"
BASE COUNT         1926 a         1337 c         1128 g         2142 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcactatct ttttaaagat gcttcttgtg ttc
//
LOCUS       DAXLPC010000116         6434 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.117, whole genome shotgun sequence.
ACCESSION   DAXLPC010000116 DAXLPC010000000
VERSION     DAXLPC010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.117"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(133..717)
                     /locus_tag="ACF3UE_002507"
     CDS             complement(133..717)
                     /locus_tag="ACF3UE_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3635851.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            complement(928..1131)
                     /locus_tag="ACF3UE_002508"
     CDS             complement(928..1131)
                     /locus_tag="ACF3UE_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635852.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            complement(1141..1563)
                     /locus_tag="ACF3UE_002509"
     CDS             complement(1141..1563)
                     /locus_tag="ACF3UE_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635853.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRDGIAIGNPTNDLTVTENYLIVSPLLALAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            1801..2415
                     /locus_tag="ACF3UE_002510"
     CDS             1801..2415
                     /locus_tag="ACF3UE_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3635854.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(2580..3404)
                     /locus_tag="ACF3UE_002511"
     CDS             complement(2580..3404)
                     /locus_tag="ACF3UE_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635855.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(3428..3583)
                     /locus_tag="ACF3UE_002512"
     CDS             complement(3428..3583)
                     /locus_tag="ACF3UE_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635856.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFILKKN"
     gene            complement(4042..4299)
                     /locus_tag="ACF3UE_002513"
     CDS             complement(4042..4299)
                     /locus_tag="ACF3UE_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFD3635857.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(4292..4561)
                     /locus_tag="ACF3UE_002514"
     CDS             complement(4292..4561)
                     /locus_tag="ACF3UE_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFD3635858.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(4692..4871)
                     /locus_tag="ACF3UE_002515"
     CDS             complement(4692..4871)
                     /locus_tag="ACF3UE_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635859.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(4887..5087)
                     /locus_tag="ACF3UE_002516"
     CDS             complement(4887..5087)
                     /locus_tag="ACF3UE_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635860.1"
                     /translation="MNKIIPLLFVLFVGEILMRHGAALHLNFVVFLGILVFCLIFWRF
                     VLTLVSLIFKLIAAIFLIGLFR"
     gene            complement(5252..5959)
                     /locus_tag="ACF3UE_002517"
     CDS             complement(5252..5959)
                     /locus_tag="ACF3UE_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635861.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNRLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGQ"
     gene            complement(5952..6389)
                     /locus_tag="ACF3UE_002518"
     CDS             complement(5952..6389)
                     /locus_tag="ACF3UE_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635862.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFENIEKNGAFYTIESEEKDNE"
BASE COUNT         2001 a         1192 c          908 g         2333 t
ORIGIN      
        1 taatattaac aaatgaataa aatccttaca acatttgaga ataagttatc agtagacact
       61 tacaaaaaat tctcatacta ttgtcacttt tctagataaa tggcaaaaat tttcagcatt
      121 aaatgacaaa aactaatgag aatttgtctt tccatttttc tcctccattt ttgccaaata
      181 acgataaatg gtggttcttg agacgttcca ccgttccgca atagtcttaa taggtgtacc
      241 gctatccact aaagtcttca gtaattccaa atcttgttca gacaattttt caggacgacc
      301 accaaaccgt cctcttgcac gagcagctgc tcgtcctgct gcggatcgtt ccaggatcaa
      361 attacgctca aattctgcaa atgccgcaaa caaatgaaac atgagctgtc ctgtagaact
      421 tgatttgtcc atcgtaatat tttcttgaat actatgaaaa ctcacaccac gctcattcag
      481 tcgattgacg attgaaatca aatcttccat atttctacct aaacgatcta agcgccaaac
      541 gacaagtgta tcgccagagc gaacaaaatc aatggccatt tctaatcctg gtcgattact
      601 ttttgcccca ctcatatgat cagtaaaaat tttttcacaa ccaaatttat ttaggctgtc
      661 ttcttgtaaa tccaaatttt gtaaaccagt agatacccgg gcgtatccta ttttcaaaaa
      721 aatcactcct tcattaattt tattgtaaca taactttatc catatagttt aactgaacat
      781 agatattgtt atgggtttat gaacatgaaa tgaattgttt ttttgaaaaa taaagcaaaa
      841 aaagaaagtg tccagaaatg ggtgatttta tgaacacttt caattagaaa aaaagaatgt
      901 cgactagaca ctcttttttt aaaatcatta tttttctttt tgatatgttt tttggtctct
      961 tttttttctt ttttcttcag aatcttctag attagaaatt gatttttgaa ttttttgtgt
     1021 ctcctgtaaa gttcgctgaa cttgtaaagc tgattcttct ttcggtaaat taattttact
     1081 tagaatatcg ctatcttgat aaaaatttgg tgtgttcaca aattctggca taaaaaatcc
     1141 ctactttcta gttaaggttc ctgaataagt cgcaatccaa ttgtttccag ctgatttata
     1201 actttgtaaa tacaattttc catagtacca ataaccattt cttttttctt tccaattccg
     1261 tgattgagga ggtctagaag gccaaccaac tttatcaaaa atcatcgttc ctgtcactcg
     1321 tatcgtttta gaagctgcta gagcaagtaa tggagaaact attaaataat tttcagtaac
     1381 agttaagtcg ttagttgggt taccaatggc tattccgtcc ctatctaaag gagttaattc
     1441 ttggttatta tctactacag tagttggttc atttgtacta tcagcaaatg taggaattgt
     1501 agttccagtt acactaattc caatagttaa aatacctaaa gataaaataa acttattttt
     1561 cattgtctat cacctcgaaa tcaaaactaa gaaaacgttt tcttaataaa tcttaacaga
     1621 taaatcaagt tatatactag aaaattcata aaatatattt ttaatgtcat aatcgtttaa
     1681 attttcttga ttgacattta tttacaaaaa atattgccat ttaaaaagaa aagtgacata
     1741 tggcttcctc gtgtatgatt agggtgtatt ttaaatagtt gcagaaagta ggtaaaagtt
     1801 ttgagagttg catacatacg tgtctcatcg atcgatcaaa atgaacaacg ccagattgaa
     1861 gaaatgaaaa aattcggtgc agagagaatt ttcatcgaga aacaatctgg cgcaacgatt
     1921 actcatcgac ctgttttcca agaagcatta gattacgtcc gagatcaaga tatttttatt
     1981 gtggaagcta ttgatcgact tggaagaaat tatgacgaga tcatcgcttc agtcaattac
     2041 ttgaagaaga aaaatgtgaa gctgatcatt actagtttac cgatcatggc tgaagcaatt
     2101 ggcaatcctc tcctggataa attcattaag gatctgatca tccaaatttt ggccatgatc
     2161 gctgaacaag aacggactga atcgaaacgt cgccaggcac aaggaattaa gatcgcaaaa
     2221 gcaaacggcg tctacaaagg gcggcccaaa ttatacagtg cagacgcaaa agatccccaa
     2281 cgtcgccttg tttacaaaag catcgttgaa gatcttaaaa atggtgttgc gattgctaag
     2341 attgctaaag actacaatgt tacgagacaa accgtgtata gaataaaaaa agacagcatg
     2401 gtcaatgaca aatagttgat catgctgctt ttattatctt ctcatcttta atttcctaca
     2461 tataattact atctataaaa ttaagtctta ctcagaacag ataaagcata aaattccaac
     2521 aaaccatttt ttacttaact aaataaagag tctgttaata taatcttcac ttatttacgt
     2581 taatccccta ctgtatttgt tggttcctta tctatatttt ctacaaaatc cttattatct
     2641 tgtgatttag cttcgtataa ttctttgtat gtcgacacat tggttatact aattcctata
     2701 gctagttctt gagactctac ttttctctct agctcctttg acaaagtgat ttgagattta
     2761 tttggttccg ttggagtcaa ttctatagat tcttcataaa aatctctata cataaagcta
     2821 tcattaattt tataaaaaaa attaaatgtt tttagcactg ccatataaca ttcaaaacat
     2881 tcttctatag ttggtttact tccttgagga gaatgaacca atttattacg tttttctatg
     2941 aaatttttaa tttcctttct tatttctttc ggaaactcaa tattaaagta ccctttaaac
     3001 atgctcccta ataatttgtc tacaggggga gattgtaaat tctcaaatat tagagttaaa
     3061 tcaggtttct cttgttgata aaattccttt acccctattt cacaggctgt aattatcgaa
     3121 ataaacctat ctctagtatt tgatatattt ttacttcttt taaggagtat aagagaaaag
     3181 gggatacttt cgtgtccatg catgtaatta actaattgtt gagcttcaga agttatatct
     3241 ctaattatat agttaacgga attaggaagt gtctttaact ctaatgaaat ttctatccaa
     3301 ttactatctt ctaatctgta tatgctcgaa gtataatttg attcgtcagc aagcatcgct
     3361 acatcccaaa cactgatcat aaaatctttt aaacgttcaa tcatttcagc aatattgcta
     3421 aaatcagcta atttttcttt agaataaaaa aaacatttat atcagaatca ataaattcta
     3481 ttttttttat tactatatcg tcatcattat cttgaccatt tatgtttatt gttccctgag
     3541 tggggagtac ttctttcaaa ttcaagttaa atttatattc cattacttct cctccaatat
     3601 ataaaaatta cttaactgta tccaaattta atatgtaaat aaatcattaa tttttagcta
     3661 aattctatga gaagtttatt tttgttgttt ttgctaatta actaaaacta gtacaaaaaa
     3721 tttaaaatag attattaaac ctattgctta ttctattcag tcatatatat aagcgtcatc
     3781 ctttagtaac taacatccca cactacaata gtattataac atatctattc aacttcaaat
     3841 tgttgaaatt taagccattt atatttactt ttcctcaact ttagaaatga ttttactaac
     3901 cttatatccg taatacgcgt aacaaacaca ttcattaata acaatcaaca ctaagctata
     3961 ttagcttttt aaatgactag ggtaaataaa ataaggatca aaaactttta agtttctgac
     4021 cctttcctta cttccgattg gttaatagtg atcttttgca gaataaataa atatcgtttc
     4081 attttcaact ctatatatca gtctatgttc atctgtaatt cttctggacc attttccaga
     4141 taaatcatgc tttaatggct caggttttcc taatccagca aagggggaac gatcgatatc
     4201 ttttattaac ttgttaatct tttttatatt gcttttgttt ccttgctcat gccaataaag
     4261 ataatcatcc caagcatcat cagaccaagc cttaatcatc agattcaacc tcgattaagt
     4321 catgtgtttt aaatgcacct ttggagaatt gttcatctcc tcgacgaatt ttttccatga
     4381 cgtaattatt agaaagtgtt ctcaacgttt cttgcataga atcataatct ctttttgata
     4441 atacaacaac tgtatcttct acatctttac ttgttacaat aagtgtttca gcatcctcat
     4501 taacttgttt catataacta cgtaaatttt ggcggaaatt tgaataagct actgcttcca
     4561 ttcctttcac cccttattta tttctataaa acaattgtac attatattgt acaattaagc
     4621 aaatgattaa tattctaact tcttataatt aaaagtgcta tcacttttag tttttaggat
     4681 aaaaagtgac gtcacttttt gagtgctggt acctcaaatc ctgctttttc ttgggcaatc
     4741 aataaatcta acgcaataca cataatcctg gattcacttt tgccgtactt ctgctttagt
     4801 tgctgcaatt ctttttgtct cttttcatcc aacgtcacgg gtaaccgttt atttcctatt
     4861 gcaattggca ttagtactct ctcctttcat cgaaataacc ctattaaaaa tatggctgca
     4921 atcaacttga atattagact cacaagggtt aacacaaagc gccaaaagat caaacaaaat
     4981 accagtattc ctaagaatac tacgaagttt aaatgtagag ctgcaccatg acgcataagt
     5041 atctcgccaa caaacagtac gaacaataga ggaatgattt tattcatatg gatctccttc
     5101 tttctcttag gttatcgggc tttgcccgct tatttcgcac cacctaagcg gcgggggcgg
     5161 ttggatcgat tggtgcgaaa taagaaccat tcccttaatt tcaaggtttt ttgttcttat
     5221 ttcacacatc ctcacttttc ggtataaatg gttattgacc ttttttcctt tcaaatcgtt
     5281 gatatggcat tcgtttacgg tcaagttcat tttggatttc ttctgtatcg tcgtaagtgt
     5341 aggtgtctaa aaaatcagtt aaagtcgtgt accagtcgtc gcctgggtta tctacttctt
     5401 ctacatattc cctcaaaaat gcttcgggta cagtgagttc ataatccatt cccattaaca
     5461 cgatagattc cgtcccacac gtcaaaaatc tagtaaatac aaggtaataa tcgtctaccg
     5521 tcgcatcttt gctgtttagc tcttccattt cttcttccat taattccatg ctctcaaaaa
     5581 ttgaataata ttctgattct gagtaatagt gtttcctgca aatcgtgtag ctgacaaagt
     5641 tttcgaccag ctcactcctt tctaggtaaa cattcatgat atatttttct gtttctagtc
     5701 gtagaagctc cgctcctttt tttaatgtgt caggacgacg tttatacacg tctaaacgat
     5761 tatggctgac tgtaaccttc gtttgactcg tttcactttc catatacaac tgttcttcca
     5821 ctctttgaat aaagtacttc atttcttcca tacaactaaa gtctttttga atccgtctga
     5881 ttacttcatt caagtgttct ttgtttgtta aaaattgcga aacatcttct gttgttagct
     5941 gataaaccac cttattcatt atctttctcc tccgattcaa tcgtataaaa tgcaccattt
     6001 ttttcgatat tttcaaaagt atctagccag tcgctagcca ttgctttagc tttcttaatc
     6061 tgtgcgaatt ttgcataagt cagttctaag gcttgatatt cggaaggttt gatagtgctt
     6121 ggtttgacac ctacttccaa gcatagtaag gcttggaaaa accattttcc attttgtttt
     6181 ttcagttctt ccagtgttcg atagtacgtc gcaatgagat tcatttcgac acctgattca
     6241 atcatttctt ccactgcgac tgacaatttt tccttgtaat gttttttggg tacacgtgtt
     6301 tcatggtata ggaacgtcat atcctccatt ttttgtgcca ttttatccaa aggtaatttg
     6361 acaaattcgt catagtaatt ttgagccata ttttttctcc tttttagttc tctaatttgg
     6421 ttaaccaata ttcg
//
LOCUS       DAXLPC010000117         6187 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.118, whole genome shotgun sequence.
ACCESSION   DAXLPC010000117 DAXLPC010000000
VERSION     DAXLPC010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6187
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.118"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..449)
                     /locus_tag="ACF3UE_002519"
     CDS             complement(<1..449)
                     /locus_tag="ACF3UE_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFD3635863.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRL"
     gene            1086..1172
                     /locus_tag="ACF3UE_002520"
     CDS             1086..1172
                     /locus_tag="ACF3UE_002520"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFD3635864.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(1293..1982)
                     /locus_tag="ACF3UE_002521"
     CDS             complement(1293..1982)
                     /locus_tag="ACF3UE_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635865.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1989..2267)
                     /locus_tag="ACF3UE_002522"
     CDS             complement(1989..2267)
                     /locus_tag="ACF3UE_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635866.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(2227..3141)
                     /locus_tag="ACF3UE_002523"
     CDS             complement(2227..3141)
                     /locus_tag="ACF3UE_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFD3635867.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(3123..3503)
                     /locus_tag="ACF3UE_002524"
     CDS             complement(3123..3503)
                     /locus_tag="ACF3UE_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFD3635868.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3953..4240)
                     /locus_tag="ACF3UE_002525"
     CDS             complement(3953..4240)
                     /locus_tag="ACF3UE_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFD3635869.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(4260..4484)
                     /locus_tag="ACF3UE_002526"
     CDS             complement(4260..4484)
                     /locus_tag="ACF3UE_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFD3635870.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4954..5124)
                     /locus_tag="ACF3UE_002527"
     CDS             complement(4954..5124)
                     /locus_tag="ACF3UE_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635871.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(5139..5672)
                     /locus_tag="ACF3UE_002528"
     CDS             complement(5139..5672)
                     /locus_tag="ACF3UE_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFD3635872.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5693..>6187)
                     /locus_tag="ACF3UE_002529"
     CDS             complement(5693..>6187)
                     /locus_tag="ACF3UE_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFD3635873.1"
                     /translation="LKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1640 a         1151 c         1042 g         2354 t
ORIGIN      
        1 agacgaaaca tagtctttgc atagccactt tgtagctcgt tgaattgttg taaagaatag
       61 cgtacccact cgtctaaatt atttaacaaa ggcagtgctt tttcgtaaat tcgtatatct
      121 acgtaaggat tttctacgtc cccgttgatt ttaaattctg taaacattac aaacatatcg
      181 taagaaagcc cagactcact tctacgacca aagcgtaaag ataagatttt ttcataagtt
      241 gcttttaaat cttctacaaa tcgtacattt gcagttgctt tgtagttact taaatctttt
      301 agttggtcaa acgtaaaacg aactgtctta tccccttttt cacgcattct agacacgatg
      361 gaaaaaaaca aattcatttc aaccggtgta aattttctta aaggaattgt atttaattca
      421 tggtggtatt ttacaatctc attagccata taatcacctc aatccaatta tgaatgacat
      481 tttttaaatg tcaagacatt catatttgac gttcaaacag acaaaatgtc cttcataaac
      541 agacaaaatg tccttcataa acagacaaaa tgtccttcat aaacagacaa aatgtccttc
      601 ataacattct gtatccattg gtagagtaag gacacagctt acggtaaaga ggtttaaaaa
      661 gaggtttaaa aagagatata aaaagagggg ggctaatttt cccgcctaaa aaccacttct
      721 tttttcttta aacaggttcg cgcatttttc aaaactgcca atccaaaacc ttgcttccta
      781 cggtcgccaa aaaggtgtga tcgctacgct ctcacattgt actgcgcagt cgcctaaagg
      841 ctcctttgct aaaaacatgt tggtaaagag gcctttgagc ggttctgaat gcttatctaa
      901 gccgttttaa gacagtcttg gataaaaatc cttatctagc tttaaagcgc cttacaggcg
      961 gtcagggcaa gccctaacaa ccctaaaata agcgatactt aaaaacacca cacaagttta
     1021 attttttaag atataataac ttgtcgccta tccgacagtc ttgcgactgg aaggaggtgt
     1081 atctaatgtt tgaattgttc atttgccccc ttcttataga agtttgtgtc tctttattca
     1141 gttattggtt gaataaccga aacaagaagt aaaatcaata aaggcgacat caacctgaaa
     1201 aaaagcccca gagaatccga cctctctggg gctttcgtgt atctaatgtt tgatcatttg
     1261 catgtttagt ttaacatgat tgccgatcaa attcaatttt gctgttgctg atctaaccat
     1321 tccttgacac tttttagata atttaatgcc gtttcttttt tcgttggatt ttgtatgttc
     1381 gttgcttgct gaagcagtgc tttataacgt tcgtaggtaa ctgattgttg ccgttctttt
     1441 cgttcctgtt cactagttga aaaagggatt gtatcactga ataaattata acaagcttct
     1501 tctgtctgcg tatctttaaa atattgcacg tcttttttgg ttcgctcata gttgtcttga
     1561 acctcttttt gctgtttttc tggcaagttt tgataaagac gagtgagttt ttccatgttt
     1621 ttatccgtca aacgtttttc ttgattcaca aaaatatcgt tcatttcctc ataacaagtg
     1681 gtaaactctt ccattttttg tgttaacact tgctcctttt tctttttatc acatgctgct
     1741 tcatactttt gagtgatatc ccctaataaa atacttcttg aaatacgttt atttccctct
     1801 aaaacgccga ataaaccact taaaacgatt gataatgtaa atataacccc tggcaataaa
     1861 aacctcttaa atcgaatttt agagcctttt aatgaatatc ttgtttgata agccttatag
     1921 ctaagccaaa taattcctaa aatactggca aaaatgagta gatagggtaa atagaatgcc
     1981 atttctattt attctcccca taccagccaa aaggctaaca gtgtcatgat taagcaacat
     2041 aagggggcaa gaatatccat tgatcgctgc ataattactt ttttctgttc tttatttcgc
     2101 tggtttaata gcgcatggtg gaattttttg acttgtgaat caattgtagt ttgtattctt
     2161 tctttggtat aaggtgcaag aaaagcacgt tgtttcttta tttcattttc tatgtcttgt
     2221 aacgttttag aacgataatt cttgttggta gtctgctcct ctttcaacgt gttggtcatg
     2281 gtttcttcga gtcggtctaa tttccggttg ttcagtcgta agagttcgtt gttctcttcg
     2341 tacttctttt gcagtttcgc gaatgctagc tcgagctctt cgtagctcgt tggttcgttg
     2401 ttgattgtag gctcgttctc gtctgtccag ctcatgtaaa atcgtctcct tttcgtaatc
     2461 ctttcctagt ttgttggatc gtactttttt ctttttgtgg atcaattcgt aagtaaaatt
     2521 tttcccacga ttcaagcaat gaatgccgaa tgttttaaga gaatcacaaa attggttata
     2581 cgttcgagtt tttttgtttt tcattgtttg atcaatcgca aaccgaattt cgtctttcca
     2641 aacaggttca tttttttctt ttaatttgat ttcagacatg gttcgttttt cgggtttctt
     2701 ccctcgttca gtgattgtta agtcatgttc aagacaaatc tcgtcattta ggtcataaca
     2761 tttgtttaaa aatgcttgac catgggcttg aaatttgttc ccagtttcca gattgacgga
     2821 gttaatgaca atgtggttat gaatatggtc tttgtctgta tgtgtgtaaa tcgcgatttg
     2881 gtggtcaggg gctatttttt tcgcatactc tgcccctagt tgattggctt tttcagcggt
     2941 aatttctcct ggtcgaaaag actggatcaa taagtgtgct tgtacacgat cgtcttttcc
     3001 atacagcatg cgaatttgtt tcatttcgct tttggcataa tcaatgtcac agtttatccc
     3061 tgttttgacg gttgctcgtg gttcggcgta attgatcgct cggctacaag aagtggttcg
     3121 gcttacttta actgttgcca tatcttttgt agctcctttt gcatgatttt taggttttcg
     3181 gataagcgtt gggcgtcgcc aggatcaacg tcgtgttggt gtgtgttgca ccacttggca
     3241 atttgattga tattcccgcc agctttggct aaatcgcgcg cgattgcctg agcaatgtct
     3301 ggcgccactt tcggtgtcac cagacgcgcg ttttgtgcct tggctttcac gaaagccggc
     3361 acactcattt gcaaagcttc agctgactgc ttcagctttg caaattcgga ttcgctcact
     3421 cgaaaactga tttgttttgg ctcggatcga taggtatatt ttttagaatg attgctagcc
     3481 aaatattgat tttgttcgct cataagtccc accctttcag tacgtcctac ggacgtatcg
     3541 ttcgcaatac cattgtacct aaaaaggtac aataagtaaa gctcactaaa gctcactaaa
     3601 gggcttggca agctctatat ttgctagcca aatacctacg tatttggtgc aaataaccgc
     3661 ttgtcaaagg ggcgcaagct cccccttgaa tccccctccc ccccactctc cacaatacaa
     3721 aaaagactag caaatgctag ccactttttg taaagtttcg cttgtttcac cttcggtgaa
     3781 attgttgcaa atcaataatt aggtagagct acattttttt cgttgttcaa agattcttat
     3841 gccatttact attaataaat ctataaatat gataattttt cggctctata atttatggga
     3901 ctgatgaatc agaattgatt cttcagtccc attttcattt tattccaaag aattaactcc
     3961 aaataccaat agaagcccat cctctatata cttgagattc cttactaaca atttcttgta
     4021 attctattaa agatttaggt aatccaaatt tatgttttaa aatatatctt ccaagaaaac
     4081 tacttaattt catactaact tcaccaacac tttttccctc actgatttct ttagaataaa
     4141 gaaagagctt ttcttttaag tcaggatagt catctatagt tgcttcattg tatactttac
     4201 taattgcatt taaaagtttt tcttctttag taaaatccat tataataacc tccctaccac
     4261 taccttctag gtgcccatgg accatgatta acccaaccat taacaataat ttttccaatt
     4321 tctcctttag cttgattcca atctacccaa catttttctt tgttacaata aagaccattt
     4381 ccatagtaag tagctgcatc aacttttatt cctgtaccga tgccagctag acaagttcct
     4441 aatattccta gaataacaca atgttttaat actttctttt tcatgattgt ttttcctttt
     4501 cgttttttta aaattgcttg ttatattaaa taatcttagt aattttatta tataacattt
     4561 tattatataa caatttatta tataacaatg attaacgtca taaaaagtag ttttgaattc
     4621 ataatcgttt aaataaaatt ataagatcag ttatttaaac agctagtaga cataatgtgt
     4681 atactaccaa gtaacgcctg taccaaggga tccaggcgct gattttgtga atttttattg
     4741 gtctaggtta aaagctcttt ttaaggcttg gttttctgcg gttgtttctt tctaattctt
     4801 tgtgaatatt gatcggtcat tttttaaata cttgttattt ttgtttgtgt ttgttatgct
     4861 ttttacatat ctcatattca tttattattc ttttctaagg ttaataatag gataatctct
     4921 ttcagaaaga ctgctcgtac gagcagtctt ttcttattta tcaagttttt ctacaaatac
     4981 ttcctcattt tgactgttgt agtaattagg attgagtttt agttcccctt ttttatttcc
     5041 tttgttggcc actgataata acattgggct aaagcttaat attcctagta ggatagaacc
     5101 gaatagcaag tgtttttttg tcataagtat ttccttcttc atttccatag ctgccaccat
     5161 tttttccaat tctttgtttg ttcgtccatt gtttctgttg cttcagaaag agtcgttgaa
     5221 ctattctctg aagactcttc cgtataagtc aactgcagtt gctcctgaag tttttcgatt
     5281 tgttggttgg cttgcagggt gagttgttgt tgctggtcga gtagtttttg tatatgagaa
     5341 ttattttgct ctttgagggc aagttgttct cgtaaaaatt cattttcttc acgcaactga
     5401 tctagcaact tgtttgcaac cacgtttttg tttggtatat aagcattttt atcgttgttt
     5461 tgttcatgtt tatgcaactt atctagcaac ctttgattgt ctaagttgcg agcaagttgc
     5521 aatactccag aacgcaatac aaccttataa ccacgctcat ttttagctat catggaagaa
     5581 tctaattttt ggatatgttt cgatattgct tgcctactca tcttaaaaag atctgacaat
     5641 tcctttattg taaaggtttc ttgtggttgc atactggttg cctcctaggt tgctactgga
     5701 ataaattatc taaatcagat aataaacttt ttttctcttt ttccgaaagt gcggactctg
     5761 tttgtttttc aagagctttt ttctcttttt ctagttgttt gatttgttgg aggagttcaa
     5821 gttctcgttt cttctgtttg attttttcgt taattgttgt agcgggttct tcgtattctt
     5881 tttgtttatc agctaaagcc aatgctttat tttggtcttc tttggttggt gcatgtttgt
     5941 taaagtcgtc tgcttttttg atctcaggtt tgaacgtaaa ttgatagcca ataacaggtt
     6001 ttccccgtcc ttttccgtat ttctttttga ttgttagtcc tttgaagatt gcagttagtt
     6061 cttgacgtat aggttttata actcgtttat ctatatcagg ttgcttataa cttttaggaa
     6121 tatctaataa ttcaagaaag tcttctttgg agaaatatgc gaaacctttg gttctgtatt
     6181 gctttaa
//
LOCUS       DAXLPC010000118         5961 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.119, whole genome shotgun sequence.
ACCESSION   DAXLPC010000118 DAXLPC010000000
VERSION     DAXLPC010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.119"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..1379
                     /locus_tag="ACF3UE_002530"
     CDS             <1..1379
                     /locus_tag="ACF3UE_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFD3635874.1"
                     /translation="GQFYVNKEVNLEKLSNLLHVCKTTLLNDINNIKKEFEEQIAYTH
                     REKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDEPDYLQLTECEFISVSKA
                     YSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRLGGFNSWELPESFFERAD
                     RFIESVTENSGRFYDKENKEILLIGFAISFLRQQVCAVTIDSKFIEEIKKRPIYNYVE
                     SAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDFQQLHQVFIDNTPEIKEL
                     VATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQTI
                     FSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYIVTNSDVHYLIYREALEA
                     VTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDAVQYENIIPISINTIDRA
                     IISAVQNK"
     gene            complement(1471..1836)
                     /locus_tag="ACF3UE_002531"
     CDS             complement(1471..1836)
                     /locus_tag="ACF3UE_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFD3635875.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1833..2198)
                     /locus_tag="ACF3UE_002532"
     CDS             complement(1833..2198)
                     /locus_tag="ACF3UE_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFD3635876.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2390..2638)
                     /locus_tag="ACF3UE_002533"
     CDS             complement(2390..2638)
                     /locus_tag="ACF3UE_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635877.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2637..2765
                     /locus_tag="ACF3UE_002534"
     CDS             2637..2765
                     /locus_tag="ACF3UE_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFD3635878.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2822..4516
                     /locus_tag="ACF3UE_002535"
     CDS             2822..4516
                     /locus_tag="ACF3UE_002535"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFD3635879.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQ
                     EEEHVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4616..4789
                     /locus_tag="ACF3UE_002536"
     CDS             4616..4789
                     /locus_tag="ACF3UE_002536"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635880.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKVV"
     gene            5167..>5961
                     /locus_tag="ACF3UE_002537"
     CDS             5167..>5961
                     /locus_tag="ACF3UE_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFD3635881.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEK"
BASE COUNT         1954 a         1133 c         1090 g         1784 t
ORIGIN      
        1 gtgggcaatt ctatgtaaat aaagaagtca atctagaaaa gctctccaat ctcctgcatg
       61 tttgcaaaac cactttgctc aatgatatca ataacataaa aaaagaattt gaagaacaga
      121 tcgcttatac acatcgggaa aaggaccgtt acactttata tttttcagaa catatacctc
      181 gatgcaagat catgcagcaa ttgtctcaaa attcgttgtt tttaaaaact tgtctgcttt
      241 atttggaaga agatgaacct gattatcttc aattaactga atgtgaattc atctctgtca
      301 gcaaagctta ttcattaaaa aaacaagtat tagcttattt taatgactgc gggatcgaaa
      361 tcgaccgcta ctcccctcga ttcactgaaa tggaaagacg tctgctgctt cttaatgtgt
      421 cgtatcgttt aggcggtttt aattcttggg agctacctga atcgtttttt gaacgtgccg
      481 atcgtttcat tgaatccgta acggaaaata gtggcagatt ttatgataaa gaaaataaag
      541 aaatcttatt gattggtttt gctatcagtt tcctacgcca gcaagtgtgt gctgtgacaa
      601 tagattcaaa atttatcgaa gaaatcaaaa aacgtcctat ttacaattat gtcgaatcag
      661 catgggaaaa cactgatttc caaacctatt ataaaaaaga agaattcgcc tttattttga
      721 cactattcaa tctttgtaat tatggtttcc attcttatca gttgattgcg gaagactttc
      781 aacagctaca ccaagtgttt attgacaata ctcccgaaat aaaagaacta gttgctacct
      841 ttgaatctca cttcaatcaa gaattattcg gaaaccaacc attcgaacgt gcgctgattc
      901 atctgatgcg ttcggcttgg gataactatc aattattcat gccagaaaaa ttttatcttc
      961 taaatgagga acagacaaat ttatataaag aagtccagac aattttttcc agctggtcca
     1021 gccagttacc ttatgatcta cggttgaatc ctaattgcat gcgggctttt gtgatcgaat
     1081 tgagcggaat tctccgtctg acaaaagaac atctgactat ctatatcgtc acaaattcgg
     1141 atgttcatta tctgatttat cgggaagcct tggaagctgt aactactttc gattttcaag
     1201 ttgcaccaac aatttattca agtatatctg atataaagaa gtatgcgcag cagtcctcaa
     1261 accgggtatt atgtgaacgt acattatata caccagatgc ggtccaatat gaaaatatta
     1321 ttcctatttc gatcaatacg atcgatcgag ctatcatttc agctgtgcaa aacaaataag
     1381 ggactgtgac aaaaatcatg tcacagcctc ttatttgttg aagatgccca tttctgtaac
     1441 aatctcttga tacacatcag gctcacaacc tcacttattt tggacatcta cgggtccgat
     1501 ctctttattt aaaaaataag aaatgatggt tcggataact accaacgccg ctagttggaa
     1561 aatatcctgc aaggtaggtt tgataatcga ttcgatgatc ccagctgaaa caagaatttc
     1621 caaacttaga agtatatagc ctcccaacat ctttttaata gcattgttct cgctgactcg
     1681 gtcgctttgc acttttgtat ggacaaataa atatttcaaa aaatccttga ttgatagaca
     1741 aacaccccaa accaataaac agatagcaaa gatatcaagt cccagtacaa gtttttcaaa
     1801 atatggaaga agaaactgca tcaactctgt cgtcatccta cctctcctct tctttgtttt
     1861 tctttgtctt ctatttcctg attcaagaaa taagaaatga ctgttcgaat gataataata
     1921 agtgcaagct tcaaaatatc tgtccaagtc ggcttgataa ctgactcgat gatatcagca
     1981 acgactagta cttccaagct taacaaaata taacttgcta gcagttttct tgtatctgca
     2041 ttacgagtat tacgttctgc atagtttttc ttgacatgag accaatcaaa aagtttgaat
     2101 agaacaagaa cgatcccgac aattaagata ccgatagaac aaatatttaa aatagcaatg
     2161 atccattcta gaaattcaat taaatttgag cgaaacatat acgctaccta ctttctttta
     2221 atttgttcct attcttttat tgtaaaagaa agttaccttg ttcgtctatt taaaagttgt
     2281 tctaatgata acggttcgct taaatttttc tttttcactc tccccttttt ctccctccat
     2341 ccataaatcg tggaagtatc caaaacaacg tagcaagtta aaataaggct tagtccgtca
     2401 tcagcttttc aaagaagcac tgtctcggtg ctttttttgt acccaaattt ctaaaaatag
     2461 aaccatacac ctcctcaaat cttttcttct tacctaccct atttttattt acaggaaaat
     2521 cagacacttc ttcttttttg tcaaaatttc ctttttcttc tcgtcctatc atttggcatt
     2581 ctaataaaaa cgaactatcc ttggatatag aaagagaaaa caaggaggcg tttttcatga
     2641 gtaaaaaatt aatcaaagtc ggcatcggtt taggtttgct tgcccttggc gctgcatatc
     2701 taggaaaaaa gacaggacta ttcgaagatg acagtcattt atatgatgaa ttcgaatcaa
     2761 tctagcatcc tatttagttg aatcactacg gacatacttg gaagacattg gaggaatcac
     2821 aatgagaaaa agtaaagcaa taatgattgg tgccggtatt gccaatatgg cagcggctgt
     2881 ttatttgatt caagaaggca aatggaaagg ggatcagatc accttttatt cattggatga
     2941 tcacggttca aatgatggtg caccgaccga cactgtagtg gatgaatatt ggaataaaaa
     3001 ccatccatta gaaaaccaaa aaggctatat tgctcgaggc ggtcgcatgc ttaattaccg
     3061 tacctatgta gatttgatgg atctgttaag tcgaatacct tctgttactg agccagggat
     3121 gactgctgaa gaagatacga gagattttga tgcaaaacac cgaacctttg acaaagcacg
     3181 tttgatggaa ggtggcaaag gaatcattga tggcggaaaa ctgggattca ataataaaga
     3241 ccgtattctt ctgactaaac tgattgctat gcctgattca gaagaagaaa aactagacaa
     3301 tatcactatc gaagaatatt tcaaagatga tccacacttt tttgaaacaa acttctggtt
     3361 tatgtgggaa acaacatttg ctttcagaac acgtagttct gctcaagaat tgcgtcgcta
     3421 tatgcatcaa atgatttatg aattcactca aatcgaacat ctagtgggcg tcaatcgaac
     3481 acgttacaat caatacgaaa gtattatgct tcctttgatc gagtacttga aagaacaagg
     3541 atgcaaaatc attttgaacc gccgtgtcac tgactgggaa ttcaaagaaa caccgatgca
     3601 agatgaaatc actgtgactg gtttgaaaat gaccaataca ctgactcaag aagaagaaca
     3661 cgttgtggtc gatgaagata cagcagttat tttcactaat gggtccatta cagattcagc
     3721 tactttagga gattacgaaa caccagctgt agaaaatatg gattatggtg cagcttctag
     3781 tctctggaaa aaagccagtg aacgtttcta caacttggga aatcctgaca aattctttgc
     3841 tgatcgagat gcaagcgaat gggtcagctt taccctgacg acgaaaaacc atttgttgtt
     3901 gaatgaaatc acccgtatca cgactcaaga accaggaaat gccttgaatt catttatttc
     3961 aaccacaccg atcacgccgt taggccaaaa agatgtcaat atgtctatcg tcgtgcatca
     4021 tcaaccgcat tttacgtctc agaaaccaaa tgaaacagtt atttggggtt atttccttta
     4081 tccaagacga cgtggcgaat ttgtggataa acagtatatt aaaatgaatg gaaaagaaat
     4141 gctagaagaa ctgattggac aactttcaaa agtagatcct ggaccagtga atattcgtga
     4201 aaaagaaaca gaaattttcg acagcgtaat aaataatatc cctgtctata tgccttatgc
     4261 ttccgcgttg ttcaataatc gtgccaaaag cgatcgacca aaagtcattc ctaaacattc
     4321 gaccaatctg gcctttacag gagaatttgt cgagcagcct tatcagatga tctttactga
     4381 acaaagtgct gtacgttctg gagaaatcgc tgctttccat tttgcgggta tccctatgtc
     4441 acgtcttgtc aaaacaccgc gttacgacaa agatattcct actctagctc gtgccgcaaa
     4501 aaaaatgttt gaataatcaa gaggttgtga aaaagctgcc ctgcatcaag taataagaac
     4561 aaccaggcta aaacagcttc ttatgttttt gatttggttg gacttattac cgcagatgca
     4621 agcttttgaa caccgtttac caagaggttg tgaaaaagct gccctgcatc aagtaataag
     4681 agcagccaag ctaaaacagc ttcttatgtt tttgacttgg ttggacttat taccgcagat
     4741 gcaagctttt gaacaccgtt taccaagagg ttatgaaaaa gtcgtttagt ttcgagtatg
     4801 aagaaaaatt ttgtgaaaat ggttcctcac gtttttgcat aaatttgact taataccgag
     4861 aaactgatcc cttctgtcat aacctctttt tatttatgtc tgtttctttt tgaaaacaac
     4921 cattttttca acgtttactc tcttgccaat ccaacatcat ctaacagata caactatttc
     4981 aatgattacc attacactaa aaaatcggaa actcacctct ccgaacacaa atacataaga
     5041 ctatagaatg tttcatttaa gaaaaaaagc gtttcattat caaaaaggta agatctcctt
     5101 taaaatgaaa ttatctgtag tactaataat gcagacaatt ttatgaatct gaaaggagca
     5161 tctccaatga aagcagtcac ttggcaagga aaacagaaaa tggaaatcag aaacgtagat
     5221 gatccaaaaa tattagaacc aacagatgca atcatccgta tcacagcaac agccatttgc
     5281 ggctccgatc tgcatcttta ccatcatggt gaagcagttt tggaaaaagg gtatgttgta
     5341 ggacacgaac caatgggaat cgttgaagaa gtgggatctc aagttcaaac attgaaaaaa
     5401 gggcaacgtg tggttatccc ttttaatatt agttgtggtc attgtcattt ctgcctgaat
     5461 cacatggaaa gccaatgtga tgaatcaaat ccagatcagt tatatggcgg gcttttcgga
     5521 tttggcaagt tgaacggtaa tcattggggt ggtcaagcgg aatatctaag agttccttat
     5581 gcagactcta cttcatttgt tgtaccagat aatgatcttc ctgatgaaaa agttttattt
     5641 ctatcagata ttttgcccac agcttattgg agcgttgaaa acgcaggagt aaaaaaaggc
     5701 gatacagttg tgattctagg ttctggtcca gtcggtctat tcgctcaaaa attcgctgtt
     5761 atggctggag cagagcgcgt aatcgcagta gatccagtac agcaccgtct agataaagcg
     5821 gctaattaca atggggttga aacttatttc ttagaagaca cggcacaagc tggaacagaa
     5881 ttgtatgaac tggctaaagg tggcgcagat gtcattatcg attgtgtagg aatggacgga
     5941 ttagagcctg tcaaagaaaa a
//
LOCUS       DAXLPC010000119         5952 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.120, whole genome shotgun sequence.
ACCESSION   DAXLPC010000119 DAXLPC010000000
VERSION     DAXLPC010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.120"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(289..2955)
                     /locus_tag="ACF3UE_002538"
     CDS             complement(289..2955)
                     /locus_tag="ACF3UE_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFD3635882.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNE
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            3297..4748
                     /gene="cls"
                     /locus_tag="ACF3UE_002539"
     CDS             3297..4748
                     /gene="cls"
                     /locus_tag="ACF3UE_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFD3635883.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQKALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            complement(4953..5768)
                     /gene="thiD"
                     /locus_tag="ACF3UE_002540"
     CDS             complement(4953..5768)
                     /gene="thiD"
                     /locus_tag="ACF3UE_002540"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFD3635884.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKDAQQETVNDYVLLESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
BASE COUNT         1708 a         1283 c         1055 g         1906 t
ORIGIN      
        1 tcttttgatg aataataaaa tgattggctt tccgtctatc ataaataaaa aaagggactg
       61 tgaccaaagt cgtgtcaaag tccctctttc cgaataaaca gtgtccaatc agatgaccct
      121 cagtattagc tcaaaatgct gattttacaa cttcttcctt aaacggtgtt ctcctgccaa
      181 ctcttcggtc acaagtcaca atattcaaca aacatgagaa gctgtttgtt gaaattgcac
      241 cttgtgactc agaattaaac ggcaggctca caacctcgtt gattcgtttt atttatttcc
      301 ttgtactcgt acaatgatca atttagtgat ttccatcaaa acaattgtca caagtgcgat
      361 tcccatacat gtaaagactt ctgtcaatcc aaatgctgat gggatagaga agacttcttt
      421 cagtcctggg atcattgtta agcagtaaag cgcgctacat acaactacag ctagtaagac
      481 acttctgtta gagaagaacc ctgcttggat agctgtttgt gtgtttgaac gtgctgggaa
      541 tgtttgcaat gtccgacacc aaatcaatgt tgaaaatgac atggctacac cgaattcagg
      601 tgaatgctgc atgccaagcc attgagcaaa gataacagca atcccaatca gcacaccacg
      661 atacgttaca gaaatcaatg ttttgtccgt aaagattcct gaatttggat ctcttggcgg
      721 gcggttcatc gtagcaggtt cagctttttc tgtacctaat gcaattgctg gcagtgaatc
      781 attgactaaa ttgatgaaca acagttgtaa tgctgtaaat ggattggacc agtcagcaac
      841 taaggcaaag atgatcgcaa tgatcgcacc taaatttcct gcaaatagat aagaaatagc
      901 tttcttgata ttatcaaaca cattacgtcc tacttctact gcgctgacaa tagaagcaaa
      961 gttatcatcc gtcaatacca tcgctgctgc atcttttgcc acatctgtac ccgttcccat
     1021 agcaattccg atgtctgctt gtttcaatgc tggtgcgtca tttacaccat cacctgtcat
     1081 agctgagata tgacctttat tttgccaagc acgaacgata cgaattttat tctcaggtga
     1141 aacacgtgca taaacagtga ctttttctaa aacttcgttt agttgatctt ctgtcaattc
     1201 atctagttcc gtcccggtca aagccaggtt tccttcttca aaaatcccga tttgttttgc
     1261 gatagcaaca gctgttgttt tgtggtcacc agtaatcatg attgttttga ttcctgcact
     1321 tcttgcttct gttaccgcct gagtcacttc agcacgtgga ggatcgatca tagcaagcaa
     1381 accaacaagg atcaaatcgt cttcatcttc aaatgataaa tcaaaattat caagtggacg
     1441 gtaagcaaaa gctagtacac gtaatgcgcg tgttgaaaaa gcttcatttt gctcttggaa
     1501 ttttttcatc aattcatccg tcatcggaac gacttcacca tttagcaata cttttttact
     1561 gcgttggaag acgatatctg gtccgccttt gacaaacaag taattttcgt tatcgatcgt
     1621 gtgtccagta gacattaatt ttcgatcaga atcgaaagga agttctgctt gtcttgggta
     1681 gttgtttcgg atttcctgat aaggctggtt taatttttca ctaaagtcga taaacgctac
     1741 ttccgtaggg tcgcccaatt tagtaccgtc ttcactgatc gatgcatcat tcgctaaaac
     1801 actgatttcg atcaagcgac gttcgtcagc tgtccatttt gaagggtcat ttgtgaaatc
     1861 cccagtatcg ccattaccta aaaagtagtc aacaactgtc attttgtttt gtgtcaatgt
     1921 accagtctta tctgtacaga tgatacttgt cgaaccaagt gtttcaactg ctggaagctt
     1981 ccgaataatg gcatgacgtt ttgccatttt attcgttccc aaagataaca cgattgttac
     2041 gatagactgt aatgcttctg gaatagcagc tacggctacg gctacggcaa acatcactgc
     2101 gctgacgata tctgcagtca tatctcctgt accttctcca agataaatac gaaacagttg
     2161 gatacctaaa atcaataaag acaatgccaa aatagccaga cttagttttt tactgaattt
     2221 atccagacct cgttgtaacg gagtgacttg ctcagttgtt gattccaaaa ggccagcaac
     2281 ttgtccgatc tccgtattat tcccagttga agtcactaag aatttaccgc gtccgtaagt
     2341 tacgatcgtt ccactgaata ccatatttgt acgatctccg attggtaccg tacttgtgat
     2401 atccgttact tctttttctg cagaagtcga ctctcctgtc agcatacctt catctacttt
     2461 taatgatccc gcatctagta aacgtccatc agcaggtaca taatcgcctg cgtctaacaa
     2521 cacgatatct cctaccacaa gttcgtttgc cggaatcgtt ttttccttac catcacgaat
     2581 cactcgagca tcgggcgctg aaaggttttt caacgcttct aaagaacctt ctgctttttt
     2641 tgtttggaca acactgatta tagaattcaa catcaatact gcaaaaataa ctaagaattc
     2701 gatgtagtca cccatgacca tctgaatcag tgcgacaatc agcaatacga taaccattgc
     2761 atctttgaaa gtttctaaga acaatttcca agttggcttc ttcggctttt cttttagctg
     2821 gttcaagcca tctctttcta atttttcctt cgcttgcgtg gtgctcaatc catcggttga
     2881 gctctgcgtt tgctgcatca acgagtcgat cgtttcttta tagaccgctt gttgtgcttg
     2941 ttccttgttt tccaaatttc atcccccatt ttttgatctt ggccctagtc ctgtctgaaa
     3001 aaaaaagaga cctaagacaa atacgcattt gtcttaggtc tcaccatttc atacaatacc
     3061 agaaaaccat ttggttaact tactgttgat attatcgcaa caaacgttgc cggttactcc
     3121 cctaaggaga tattcaactg tactaatatc ctaccttatt aacctacaaa aagcaactac
     3181 tttagcccga tttacctaca ttttcatgaa aggagtgaaa agtatattca ccttggtagg
     3241 cttctttctt ctatcatgct atactaatgt tattgtatgt aaggaggaac atttttgtgg
     3301 tatctagtat tataaccgcc ctttatctat taaatgcact tattgctttg gtggctattt
     3361 tgatcaaacc ccgagatgta gcagccattt gggcatggct cttagtattg tttgcccttc
     3421 ctggggtggg ctttgtatta tatttatttt tcggacgtgg attaacggat aagaaaaaat
     3481 tctatctccg acaaagtgac ttgaaagaat tagaaaactt tcagtctttt agaggagata
     3541 ccattgaaca ttacgatcct gacatgggcg ataaagacaa acagcaattt gtcgacttct
     3601 tctcttcatt aaatcgtatg ccgctgacaa gaatgaattc tgtcactctt ctcacagacg
     3661 gacaagagaa attggattca ctgcttcaag atctaaaaaa agccaaacat tcgatccata
     3721 tcgaatatta cgcatttgtg acagataata tcggccagca agtcttacat gttttagaag
     3781 aaaaagccgc agaaggcgtg gaagttcgaa tattatatga tgcatttggc tctcatggta
     3841 caaaagcaaa agatttcaat cgtctaatca aaaatggtgg acatgtccat acatttgtta
     3901 cctcacaaaa ggcattactt cgtttccgat tgaattacca tgatcaccga aaaatcgttg
     3961 tgatcgatgg aaagattagt tataccggtg gtttcaatat tgccaatcaa tatgtaaata
     4021 caacaaaaaa attcggctat tggcgcgata cgcatatacg gattttcggt gccgcttctt
     4081 ctttgctcca gcttcgcttc ttaacagact ggaacgtctc ggtacctgaa gaaaaaaagg
     4141 tcggctatca tttgaattat ttctttaaaa aagcagatcg agatgaatct aagcttgctg
     4201 atacatccat ccagcttgtt tcaagcggac cgaataacga aagggaacaa atcaagcttt
     4261 catttatcaa attgattact tctgctaaaa aacgtgtttg gatacagaca ccttaccttg
     4321 ttcctgatga aagtgtcatt gctgctttaa aaatcgcaac tgcctctggt gtagatgtga
     4381 aaatcatgat tcccaacaaa ccggatcatc cttttattta tcgagcaaca caatattatg
     4441 ctcggcagct gatcaaggaa aatgtacaaa tccttgtcta tgagaacggc ttcctccatg
     4501 caaaaacatt gataatggat gatgaaatct gcatggtagg ttcagcaaat caagatattc
     4561 gtagctaccg attgaatttt gaaacaagtg ctgtcattta cgatcctgag tttttagaag
     4621 aacttgctac tcagttcaaa gaagatgaga cacattgttc atccatgaca actgaaacag
     4681 tcaaggaaat gtctaactgg ctattattca agcaacaaat ttctcgatta ttttctccaa
     4741 tcctataatt tttttattca agtagagaaa aatatactaa gattaaaggg actgtgacaa
     4801 aaatcttgtc acagtccctt cttccgaaca aacggtgttc tcctgccaac tcctcggtca
     4861 caagtcacaa tattcaacaa acatgagaag ctgttttttg aacttgttcc ttgtgactcg
     4921 gagctggacg gcaggctcac gacctctttc ttttactcta attcaccagc tgcccaatga
     4981 ttgatgggtc catatttgtg ccctacattt atttcttcac gaattgcacg gtttacatag
     5041 tcttttgcca atcggatcgc ttgttcaact gtttttcctt tcgctaactc agctgcaata
     5101 catgcagata gcgaatcgcc agttccgttg atccggtcgg taggataaaa tggtgcattt
     5161 aaccaaaacg attttcctga ttcgagcaat acgtagtcat tgactgtttc ttgctgcgca
     5221 tctttagcat gatgtccttt gatcataacg ttttttgcac ccatatcttg cagttctttt
     5281 gctgcttgca caaaatcttc ttcagctgct aatgtccgtc cagtcagctt ttctgcttca
     5341 taaaaattag gtgtcagtac ttcggccaaa gggacaagct tttctttcaa gctttgcaaa
     5401 gcagattctt ctagtaaaag atttccatgt ttcgttacga ttacgggatc cacgactaat
     5461 ggtccaaaat catatttttg gtaatttttt acaactgtct caatcaactt tgaatctgct
     5521 agcatacctg ttttagctgc acgtatttga aagtccttcg caatcagttc aaattctttg
     5581 tcgataaaat ctgttggcaa tgtcacactt gctccgattc cgtaagaatt acctgcaaca
     5641 catgcggtca tgacagaaac accgtaaaca tttcttgtaa agaatgtatg catatctgct
     5701 tgcatccctg cgcttccatc gctatctgat cctgcgatcg tcattgcttg tacatactga
     5761 tcttccatca aatcgattcc tccattttta taaaaagatt tttcataatg ctgttactgt
     5821 ttctatcata tgtttttcaa agtatccctc agtaaatata ccactacctt ttcttggtaa
     5881 tcaaatttat ttgaaaaaac atttgtaata aatcagaaaa tagttgtcat ttgtttgtat
     5941 tcgctattct aa
//
LOCUS       DAXLPC010000120         5912 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.121, whole genome shotgun sequence.
ACCESSION   DAXLPC010000120 DAXLPC010000000
VERSION     DAXLPC010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5912
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.121"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(99..1229)
                     /locus_tag="ACF3UE_002541"
     CDS             complement(99..1229)
                     /locus_tag="ACF3UE_002541"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFD3635885.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACF3UE_002542"
     CDS             complement(1878..3080)
                     /locus_tag="ACF3UE_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3635886.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACF3UE_002543"
     CDS             complement(3140..3343)
                     /locus_tag="ACF3UE_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFD3635887.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACF3UE_002544"
     CDS             complement(3485..4552)
                     /locus_tag="ACF3UE_002544"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFD3635888.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACF3UE_002545"
     CDS             complement(4610..4717)
                     /locus_tag="ACF3UE_002545"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635889.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACF3UE_002546"
     CDS             4880..5692
                     /locus_tag="ACF3UE_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635890.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1748 a         1219 c          949 g         1996 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgggctct ataatttatg
     5881 ggactgatga atcagaattg attcttcagc cc
//
LOCUS       DAXLPC010000121         5835 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.122, whole genome shotgun sequence.
ACCESSION   DAXLPC010000121 DAXLPC010000000
VERSION     DAXLPC010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5835
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.122"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            194..1090
                     /locus_tag="ACF3UE_002547"
     CDS             194..1090
                     /locus_tag="ACF3UE_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFD3635891.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1240..2181)
                     /locus_tag="ACF3UE_002548"
     CDS             complement(1240..2181)
                     /locus_tag="ACF3UE_002548"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFD3635892.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2307..3428
                     /locus_tag="ACF3UE_002549"
     CDS             2307..3428
                     /locus_tag="ACF3UE_002549"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFD3635893.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3686..5188
                     /gene="eat(A)"
                     /locus_tag="ACF3UE_002550"
     CDS             3686..5188
                     /gene="eat(A)"
                     /locus_tag="ACF3UE_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFD3635894.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5255..5782
                     /locus_tag="ACF3UE_002551"
     CDS             5255..5782
                     /locus_tag="ACF3UE_002551"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD3635895.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
BASE COUNT         1918 a         1030 c         1223 g         1664 t
ORIGIN      
        1 gataacaaat tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga
       61 agaatgattt atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa
      121 acgttttact ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag
      181 tgaggcggaa aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta
      241 ttttttgcct tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga
      301 attcattaaa tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta
      361 tggatttgat atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt
      421 atttttttgg aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga
      481 accggcaatc gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa
      541 acataatagt tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga
      601 tctatttttt ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga
      661 atttataaaa agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca
      721 acctggatat cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct
      781 ggaactgttg cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt
      841 tcaaaagaaa ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga
      901 aaatattttt ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc
      961 atttaagcca atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg
     1021 atttatcact aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga
     1081 aaacaaataa aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc
     1141 ttatggcatc atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga
     1201 accagctgct gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc
     1261 ttcttttgca tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt
     1321 ttgtcctttt cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt
     1381 gatcaggtct tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga
     1441 agcaatatgt tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga
     1501 agcaaattca gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc
     1561 agcaatatta caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt
     1621 tcgccaaatg gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa
     1681 gacttctaca actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat
     1741 ttctccatca cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt
     1801 gatcccaaat aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa
     1861 tccatttagt aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa
     1921 catatcatct aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct
     1981 ttcgatgatt tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa
     2041 gtcagcaatc aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa
     2101 gaggacctca tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc
     2161 cccagctatt gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta
     2221 tatagaaaaa tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt
     2281 acttaagaag aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag
     2341 gaagtgcttc ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag
     2401 gaagaaaaat caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt
     2461 acgcgctcag gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa
     2521 aaatcagcta tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac
     2581 aagcattggg gttagatcta cttgataaac caacggatca aactatccga cttgcttcca
     2641 gttatgcctt aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg
     2701 tcactttagg aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg
     2761 cttctttaga agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg
     2821 atcgaagaaa cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc
     2881 catatacagg tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata
     2941 cgacgctagc tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct
     3001 gggaggtgga tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc
     3061 tttttttgtt gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat
     3121 tggaaaaaaa gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc
     3181 aaacgatcca cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac
     3241 caataatcgc tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc
     3301 caattgtctt aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc
     3361 aaacattaga aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc
     3421 cgaagtagtt gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt
     3481 gagggatccg tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct
     3541 tgtggagaca aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg
     3601 ggtctttttg tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg
     3661 gtcttttttt acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg
     3721 ctacgacagc caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg
     3781 gaaactagga cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca
     3841 aaacaaacta ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca
     3901 acagacaaaa gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga
     3961 gatatgggaa atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag
     4021 agaattcagc acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt
     4081 ggatgacact catttcccgt taatcgatga accaacgaat catttggata tctctggtag
     4141 aaaacaagta gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga
     4201 ccggggattt atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga
     4261 actttatcaa gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga
     4321 aatggctcaa aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga
     4381 aaaagccgaa tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat
     4441 cgatactgaa tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat
     4501 gaaacgatcc aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact
     4561 attaaaagat atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa
     4621 gcgactttta agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat
     4681 tcattttaca atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa
     4741 gtcatccatt atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata
     4801 ccagccaaaa catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac
     4861 gttggcggaa tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg
     4921 aaagcttggg atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca
     4981 acggaaaaaa gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga
     5041 tgaaccattg aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa
     5101 cgtgaaacct gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac
     5161 tgagattatt tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt
     5221 taaggggaac tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga
     5281 aacaacttgg aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa
     5341 aggacagatg caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac
     5401 gaaaatcatc cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg
     5461 tctcagcttg ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga
     5521 tggactgcca agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt
     5581 cccaaatggg gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg
     5641 catcgaagac gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat
     5701 caatgcttat tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac
     5761 agaattggtt tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc
     5821 actgcttttg cttag
//
LOCUS       DAXLPC010000122         5689 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.124, whole genome shotgun sequence.
ACCESSION   DAXLPC010000122 DAXLPC010000000
VERSION     DAXLPC010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.124"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(488..1297)
                     /locus_tag="ACF3UE_002552"
     CDS             complement(488..1297)
                     /locus_tag="ACF3UE_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFD3635896.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="ACF3UE_002553"
     CDS             complement(1297..2043)
                     /locus_tag="ACF3UE_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFD3635897.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="ACF3UE_002554"
     CDS             complement(2061..2528)
                     /locus_tag="ACF3UE_002554"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3635898.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="ACF3UE_002555"
     CDS             complement(2528..2938)
                     /locus_tag="ACF3UE_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFD3635899.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="ACF3UE_002556"
     CDS             complement(2949..3962)
                     /locus_tag="ACF3UE_002556"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3635900.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="ACF3UE_002557"
     CDS             4179..4913
                     /locus_tag="ACF3UE_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3635901.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..5607
                     /locus_tag="ACF3UE_002558"
     CDS             4897..5607
                     /locus_tag="ACF3UE_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3635902.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSGSVAKF"
BASE COUNT         1832 a         1195 c          942 g         1720 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgcttt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatccggtt ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa
     5641 agatagcagg aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DAXLPC010000123         4858 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.126, whole genome shotgun sequence.
ACCESSION   DAXLPC010000123 DAXLPC010000000
VERSION     DAXLPC010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.126"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            235..1875
                     /locus_tag="ACF3UE_002559"
     CDS             235..1875
                     /locus_tag="ACF3UE_002559"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFD3635903.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2029..3351
                     /locus_tag="ACF3UE_002560"
     CDS             2029..3351
                     /locus_tag="ACF3UE_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFD3635904.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3413..3844)
                     /locus_tag="ACF3UE_002561"
     CDS             complement(3413..3844)
                     /locus_tag="ACF3UE_002561"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3635905.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3908..4744)
                     /locus_tag="ACF3UE_002562"
     CDS             complement(3908..4744)
                     /locus_tag="ACF3UE_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFD3635906.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
BASE COUNT         1499 a          963 c          902 g         1494 t
ORIGIN      
        1 ctatttatct atctaacata tcctttattc ttctactttt ctttctttag catataagag
       61 atacgcatag taatcaagca aggattgttg atataaaaag aacaaatacc gctattttga
      121 tttcttttga ctctattact catataaata aaatttatta tacctgctct ttttgactat
      181 atcctcatct gactcctata cttcgtttgt attaaaactt aggaggaatc attcatgctt
      241 acagggctaa acttattaaa taatcctttt ctaaataaag gaacagcttt tacaaaagaa
      301 gaacgggcaa aatacggaat cactggtatg cttccaagta ctgtccaaac attggaacaa
      361 caatctgtcc aagcttacgg tcaatactta agcaaacaga ccgatttgga aaaacgtatc
      421 ttcttaatga atctattcaa tacgaaccgg acattgtttt ataaattgat gggcgaacat
      481 ttagttgaat tcatgcctgt cgtttatgat cctgtcgttg cggattcaat cgaacaatac
      541 aacgaaattt tcttgaaacc acaagatgct gtatttcttt caatcgacga accagaaaat
      601 atcaaagcaa gtttgaaaaa cgcagcagat ggacgcgaca ttcgtttgat cgttgtgaca
      661 gatgcagaag gaatcttagg tatgggtgac tggggtgtga acggtgttga catcgctatc
      721 ggtaaattga tggtctacac tgccgcggct ggtatcaatc ctgcacaagt cttgcctgta
      781 tcaatcgacg ctggtactaa taacgaagaa ttattgaata atccattata cttagggaat
      841 cgtcatgctc gtgtagaagg cgaaacttac tacgaattca ttgatcaatt cgttcaatca
      901 gctactgaat tattcccaga attgttatta cattgggaag attttggacg aggaaatgct
      961 gcaacgatct tagaaaaata cgaagataaa atcactactt tcaatgatga tatccaaggc
     1021 acaggaatcg ttgtactagc tggtgtatta ggtggattga atatatcagg tgagcaattg
     1081 aaagatcaaa cgatcttgac atttggtgct ggtactgctg gtgtaggtat cgcaaacatc
     1141 cttttagatg aaatgatccg tcaaggtgta cctgaagaag aagcacgcca acatttctat
     1201 caagtagata aacagggttt attgtttgaa gatacaaaag gattgactcc tggtcaaatc
     1261 ccattcgctc gtaaacgctc agaattcact aatgctgatg aattgacaaa cttagaagca
     1321 gttgtaaaag caatccatcc aacgatcatg atcggtactt ctacccaacc tggagcattc
     1381 actgaagaaa tcgtgaaaga aatggcggct cataccccac gtccaatcat catgcctttg
     1441 tctaatccaa caaaattggc agaagcaaaa gcaaaagatt tgattgaatg gacggacgga
     1501 aaagctttag ttggaacagg tatccctgct gctgatgtgg aatataacgg tgtaacttac
     1561 caaatcggtc aagcaaataa tgcgttgatg tacccaggtt tagggcttgg tttgattgct
     1621 tcaacagcta cacgagtaaa tgctgaaatc atttctcaag ctagtcgagc attaggcgga
     1681 atcgttgatg taacaaaacc aggagcagct atcttgcctc cagtagcaaa aatcactgaa
     1741 ttctctcaaa cgattgctga aactgtcgca aaatcagttg ttgcacaaaa attgaatcgt
     1801 gaagaaatca cggatatcaa agaagctgtt gaatctgcta aatgggttcc tgaatataaa
     1861 tctttagaag attaagattg ttatagtaaa agaacataca gaaactttgt atgacgtcta
     1921 aaaagaaaaa agcgactgcg gcaaaacagc agccagccaa ctactgctct tttgccgctt
     1981 ctctttggct tttttcatac gatacagaat aagaaaggat ctgtaaaaat ggcacaaaaa
     2041 acaacaaccg caactgcagt tgaggaaaag aaaaaagaag ggttttggtc aacaaaaatt
     2101 accggcgtaa gtttgcccct ttatttgatc atggtccttg tcctgatcat tgcaatggct
     2161 ttaggaaaat taccgacgaa tatgattggc ccaatcgctg ttttggtcat tttcggtaat
     2221 ttatttcatt ttatcggaac aaaaatccct atagtcaaaa gttatttagg tggtggctcc
     2281 gtttttgcga tctttgcctc tgccgcgatt gctacatttg ggatcttacc tgagtatgta
     2341 gtaaaatcca cagaaaactt tgtcagcaat atgggctttt tagactttta tattgctgcc
     2401 ttgattactg gtagcatcct tggtatgaac cgtaatctat tgatgaaagc ttctgttcgt
     2461 tttattcccg ttgcacttat ttcaatggtc gtctcctttt ttgccgtagg actcgtaggt
     2521 atgcttatcg gaaatggttt tgcaaattcc gttttatata tctcattgcc cgcaatggct
     2581 ggtggtgttg gagccggagc tgtaccttta tcaacgattt atgcaaatgt tttaggtacg
     2641 gacgcttctt ctatcatttc ccgcctgatt cctgcgacag caatgacaaa tgtcctagct
     2701 atcattggtg cagcgttagt tgctcgtgcg ggacaatcaa tgccaaaatt caacggtaat
     2761 ggtaaattaa tggaaaaagg cgaccttggc gatggaaaac ctagaaatgt aaaaccttcc
     2821 attccacaat taggtgtcgg tttgatggta tcattgactt tcttcatctt aggacaaatc
     2881 tgtaactatt ttgttcctaa agtccatgct tacgcattca tgatcattat cgttgttatc
     2941 tgtaaaatcg caaacctatt accagaatat tacgaagatg cagctatcat gttcaacaac
     3001 ttgattgtca aaaacttgac agcagctgtt cttgccggta tcggtattgc gttattgaat
     3061 ctaaatgtat tggcttctgc tttgacatgg caatttgttg tcttatgttt gacaagtgtt
     3121 atcgcgattt cagtagtttc aggatttgtc ggtcgtttgt ttggtttata tccaatcgaa
     3181 tcaactatta ctgctggctt atgcaacaac tcgatgggtg gtacaggaaa tgtagctgtc
     3241 ttatctgcag ctaatcggat ggaacttatt gcttttgctc aaatgggcaa tcggcttggt
     3301 ggtgccatcg ttttgatcat ctcaggtttc ttgatgcaat tactttctta gtcaaaaaaa
     3361 atacctgatc atcaagtatc ggcttgatga ccaggtattt tttgataaaa atttacagga
     3421 ttttcaaaaa tcttttttgc attttatcgg aatgataacc gatgcgttca taaaatcggt
     3481 gtgcttctac tctgtattct gcagaattaa gtcttattgc tgatattcct cgtcttttcg
     3541 cttcttctac gccagtcatc aaggcctttc cgattcctct tttttcagca tgtttagaca
     3601 cagcaagtgc cataatattg aacatcggat cgctgaaaat cgattcatag gactccgctt
     3661 gtacatagcc agctgctttt ttagaagtag gatcttcata gaccaagaaa aaattttttt
     3721 ctggctcctt caacagtttc ttcatttgtc tcaccgtaac ggttaatggt acatcatatc
     3781 ctaattgttc cgcattgatt tctcgtagtg cttctgcatc tcctaaacgc atttcccgca
     3841 acatccaaat caccagccaa tttttatttt tttaaatgaa tttttttatc acagtatact
     3901 ccttttttca cttaaaaaaa gacttttcag tgattttgac ttgcttgaat ccagatcctt
     3961 ctaatgtttg caagatgacg aaagcattgt aaagattgat caaaagaacc acgatgacaa
     4021 tcgcttgaaa aataaaggtc actttttttg gagacaaaac cctgctaaat cttgctcccc
     4081 acaaacctcc aataacagca gcggggataa cataaaacaa catagataaa tcaaagcgca
     4141 taaagctact tgttaaagca atcgttacca attttgccag ttgagaaaag aaaatcgtag
     4201 atagagaata tagtgttgct tcttttattg gcaatgcaaa catcagcatc aacaaagaaa
     4261 cattgactgg tccaccacca atacctaaaa aactagctaa aaagcccaga acccccccac
     4321 atataaggta ccaagtccat gacgtcaaat gaaattttgg ctgatgatgc ttggtgtaga
     4381 agaacgcaaa aaccaaggtc aataccgtca aaaaaatttg gatcagctgc acatgcttct
     4441 cgttttcaaa taactgtaaa aaaacttcga atacaatgtt gccgactact cctccaacaa
     4501 cagctccact agatacccaa ccgacaatct gccaattcag tgatttcccg cttgatactt
     4561 gtcgcacagt cgaaacaatg gacatcgtga ataccgcaac tgttgagtaa aaagaaatcc
     4621 ctgcaacaga atgggcgccg ataagatcaa gaatcggttt gatcaacacg cctccaccca
     4681 tcccggaaat agcgccaact gtgttcgcca gaacgatcac cacaaaataa atcagaccaa
     4741 tcatcttgta tttcctttct cttgtttata tcttttagcg attgttactc ttttctttta
     4801 ttatacagta aaagaaacaa acgaggcttc gaaagctttt ctacttttta aggaaatt
//
LOCUS       DAXLPC010000124         4751 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.127, whole genome shotgun sequence.
ACCESSION   DAXLPC010000124 DAXLPC010000000
VERSION     DAXLPC010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4751
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.127"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            137..481
                     /locus_tag="ACF3UE_002563"
                     /pseudo
     CDS             137..481
                     /locus_tag="ACF3UE_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde
                     dehydrogenase"
     gene            512..832
                     /locus_tag="ACF3UE_002564"
     CDS             512..832
                     /locus_tag="ACF3UE_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFD3635907.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(861..1325)
                     /locus_tag="ACF3UE_002565"
     CDS             complement(861..1325)
                     /locus_tag="ACF3UE_002565"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3635908.1"
                     /translation="MVTYNWIKLREHPELVKQSAKWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(1454..2703)
                     /locus_tag="ACF3UE_002566"
                     /pseudo
     CDS             complement(1454..2703)
                     /locus_tag="ACF3UE_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(2732..3049)
                     /locus_tag="ACF3UE_002567"
     CDS             complement(2732..3049)
                     /locus_tag="ACF3UE_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFD3635909.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(3075..3395)
                     /locus_tag="ACF3UE_002568"
     CDS             complement(3075..3395)
                     /locus_tag="ACF3UE_002568"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFD3635910.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDIINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(3796..>4751)
                     /locus_tag="ACF3UE_002569"
     CDS             complement(3796..>4751)
                     /locus_tag="ACF3UE_002569"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFD3635911.1"
                     /translation="RYGDRVKNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYH
                     KVLATAKAVEIYRSGNYGGRIGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPM
                     VKGYYTEEFLELCQKQSIYFDPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEE
                     TPFHPERYYEVFDLPGKKMNNSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGRE
                     HEERYMDEKGIVQDDYRIEFIGQHLRYLIKATEEGANCEGYMLWAFTDCVSPMNAFKN
                     RYGLVRIELNDERSRTLKKSASWYQTLIDKRELDLPDEIYK"
BASE COUNT         1461 a          991 c          790 g         1509 t
ORIGIN      
        1 ttcgctagag tctttagaat ttctgtagta aaatcgttca tatggaagtc ctcttttctg
       61 tgaatgtgtt gtggtaactc tattctacag aagggacttc cttttttcta tttacacaaa
      121 atattttaca ctctcagaaa aagcgaaaaa tttagtaagc ttacaaaacg gcacaatctc
      181 tccattacag atggcatcgc aagctgtcaa aaaatttgga acagtccaag taactggtgt
      241 ttatatgact ccagcttctt cttacccgct gcaagaattt tttatgcggg atatcgctgt
      301 caagcatgga caggcaccaa ttatccatct aatgccaaaa atttacgaaa tgattgcaga
      361 aggactattc gatcctacac aaatcattac tcattcgctg ccactatcag aagcagcaca
      421 agcatatgag atctttgaca aaaaagaaga taaaaatata aaagttgttt tgaaaccttg
      481 aattcagtaa aaaatacagg tgattttctt tatgcccaaa atcaaacgaa atacccatga
      541 gatcgaaata ggaaaagaag aagatatcga aatacgagga cgtcgcttcc gcttctattt
      601 ccaaaatcgt tacacattga tctcactggc tgtcgattta ttaaccggga ttttctatat
      661 ttttggaagc cttgcttcct taactaaaat ccccgatcga tatggcacct atttttattt
      721 ggctggtgct attttcttga cgattcgtcc tattctcaga atcgtaagga acatttttat
      781 ttacgacgaa aaaaaagcaa tgaagagaac aagcaaaaaa aaagaggcat gagatttgaa
      841 aaaatctcat gcctcttttt tcaccctatc gtatcacttt gatacagacg agcggtcgtc
      901 ccactttctt ccttgaccat tgtcaaaaat gtccactcgt atcgttcata aaacgtggta
      961 tgatctgtaa ttaagtaaag tttttcgtac ccaagttgat gcatttcttt tctgatttcc
     1021 gctaatatcc gcttggctat cccctgctta cgcttttccg gttcaacaaa cagggcacaa
     1081 agatttggtg tcaaatcagg gcggttatgg aagtcgtttt caataacgcc cgctcctccg
     1141 acgatggttt ctttttcatc taagaccaca taccattgag gaatactttc cttattagcg
     1201 attccagtac gaatactttc ctcatacaca acagcaggaa ctccccattt tgatgaaaac
     1261 cacttcgcac tttgttttac taattctggg tgttctctta atttgatcca gttatatgta
     1321 accaatgttt aaacctccga ctaaaataaa acgtttacaa aaattataca agtctttatg
     1381 aaaattagca atgacaacaa tagtgatgta aaaaaaacgg aaaacaatca cttgttctcc
     1441 gttttttgat taatcaagca tctaaagctt cttttcttct ttcttggatc gtagctacct
     1501 tgacgaacgg tagatagatc aaaatagaaa gaaccaaatt gacagcggct agtacaccac
     1561 ctgcaatact ttttgttgcc aatacaccgc caataattgg tggagttacc catggaggca
     1621 taacggtagc tgctggcact aaacctgtag aagtcgcaaa gtaagcaaca ctaactaaga
     1681 ccattggtgt caaaataaat ggaatgaaca tgatcgggtt caacacgata ggtaacccaa
     1741 acatcgttgg ttcattaata ttgaagacac ctggcgcaat cgacaagttt gttacaacca
     1801 tatatggttt gtttttacgt cctactaaat aaatagctaa cagtaaacct aaagttgcac
     1861 ctgttcctcc taagttgaca aagctgtcaa agaaaggttt gttcacgata aacggtgcgc
     1921 tatgtccagc tgcgattgca ttaacgtttg cttcaatggc tggcgcattg attgtttgca
     1981 tcaaaggatc gaccatattc gctccgtgta aaccaaagaa ccataagaat ggtgtgataa
     2041 atgcaagcag taaggcagat ggataagagt ttgcaagtcc cataaatggt tcttggacca
     2101 ctgtatagaa agaacctacg atatcatcaa caccgaatgc agcaaaaatt gcagcaacta
     2161 aagcaaacgc agagatagtg atcattgctg gtagtaatga agcaaatgct tttgcaactg
     2221 ccggtggcac accatcaggc attttgatga tcaatttttc atttccgctt aaacgtacaa
     2281 agatttctgt tgaaataatc ccaacaataa tagcaataaa taaaccgttt gagctcatac
     2341 ctaatgctcc gcctaaagcg aagaaagagc ctaaagaaat cacacctgcg gaaacaccgt
     2401 cttttcggta gccgttagct aaatgataag caagaaagca atcaagacag aaagaatggc
     2461 aaatgtaccg ttccaagcag cagccccgaa tcctttccat gattcaccac caaaaattga
     2521 gttcatcaat tcttggaacc cgggaatcgg taagttattg atcattactg ctaatgctcc
     2581 taagatcatt aacggcatac tcaccataaa tgagtcccga atcgcaacta aatgccgttg
     2641 tgcaccaatt tttgatgcta caggtataaa atgtttctcc ataaatgcaa caaatttatc
     2701 cataaatctt ccctcttttc tttactgtag attacgcgtt caatcgacga tacagatcaa
     2761 tgatctcttt tgctaaatct gtaaaagcta tggatgtcat cagatgatct tgactgtgga
     2821 ctgtcaaaag cgtgacttca acgtgatttc cttgtgcttc ttgtgtcagc atctctgttt
     2881 gagagtgatg tgcttggact aaagattcct ctgcatcttt gattttttca tctgctaaag
     2941 tgaaatcacc ttttttcgca gcagcaatcg cttccattgc atcgcttttt gcatttccgc
     3001 caaacatgat cagacccatg atggcttcta gatttttttg atcttccatt tattgtatcc
     3061 tccgataatt tttattattt gtttattagt ttttctgctt ggtcgagtac tttttcacca
     3121 ttcatcatgc catagtcagc catattgatt atatctaaag gaatgccttt aggtgctagc
     3181 ttttcagcaa attgattttg cataaagcgt acttgcggtc ctaaaagtaa aacgtctaca
     3241 tttttagatt ctagttgatt atccgcatct gaagcagata cagcaaagat gtctgcttcc
     3301 attccttttg cttctgctgc cttttgcatt tttgtgacta ggagacttgt actcattcca
     3361 gctgaacata caagcatgat tgttttcttt tccattttaa acacgttcct ttctatactt
     3421 acacttgtat ataagcaagt agcgtgccaa ctttgaaagc gctttaaaaa gttgatatca
     3481 tcacatttaa ggtctatacc aagttgcata cacactaaaa aagaaagtgc acactaaaca
     3541 cacaaattaa tttttattac cttttttctt ttaacgtgca caaaaaaagt tgtgacacaa
     3601 aacttgtcac aacttttttt cgaataaacg gtattcaaaa gcttgcatct gcggtaataa
     3661 gtccaaccaa gttaaaaaca taagatgttg tttttacttt gctattctta ttacttgatg
     3721 caggacagct ttttcacaac ctcttttatt tcaaataacc agtaaataca atgaacatct
     3781 acaaaaaact tctatttatt tatagatttc gtcaggcaaa tccaattctc tcttatcaat
     3841 caaagtctga taccacgaag cagatttttt caatgttctg cttcgttcat cgttcaattc
     3901 gattcgaact aatccatatc gattcttaaa tgcattcatt ggtgacacac agtcagtgaa
     3961 tgcccataac atatagcctt cgcaatttgc gccttcttct gttgctttga tcaaataacg
     4021 caaatgctgt ccgataaatt cgatacggta atcatcttgc acgattcctt tctcatccat
     4081 ataccgttct tcatgttctc ttcccatacc gttttctgtt atcagccaag ggatattatg
     4141 ataattttct tttagataca tggctatatc atacatgatt ttcggataga tttcccatcc
     4201 cctggaatta ttcattttct tcccaggtaa atcaaagact tcataatatc gttctggatg
     4261 gaaaggtgtc tcttcattcc attgataacg aggagcgcga acgcgtttag gataatattg
     4321 attgattcca aggaaatcta ctgtatgatg ctgaatcgtt tctaaatcct ctgttgcagg
     4381 atcgaaataa atcgattgtt tttgacacaa ctccaggaac tcttctgtgt agtacccttt
     4441 taccatcgga tcaaaaaata ctcgattata aaacaaatca tacatataag cagctttttg
     4501 gtcttctgga gaattagatc gagcatagac catttcagga tttaaaatac agccaatcct
     4561 tccaccataa tttccgctgc ggtaaatctc tactgcttta gccgttgcta aaactttatg
     4621 ataattccac atcatccact tttttgtgtt ttgttcatgc ggccagcgaa cagcatccaa
     4681 atagcaacgc gtttggggaa cgattggttc gttgaatgta aaccagtttt ttaccctatc
     4741 accgtaacga t
//
LOCUS       DAXLPC010000125         4686 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.128, whole genome shotgun sequence.
ACCESSION   DAXLPC010000125 DAXLPC010000000
VERSION     DAXLPC010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4686
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.128"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            1163..2086
                     /locus_tag="ACF3UE_002570"
     CDS             1163..2086
                     /locus_tag="ACF3UE_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFD3635912.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            2102..2641
                     /locus_tag="ACF3UE_002571"
     CDS             2102..2641
                     /locus_tag="ACF3UE_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFD3635913.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
     gene            3326..3499
                     /locus_tag="ACF3UE_002572"
     CDS             3326..3499
                     /locus_tag="ACF3UE_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635914.1"
                     /translation="MLKKTVLVLGSISLGILGFSPMLLSVIGKNNSNGELKLNSNYYN
                     SPNEELFVKETDK"
     gene            3950..4483
                     /locus_tag="ACF3UE_002573"
     CDS             3950..4483
                     /locus_tag="ACF3UE_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635915.1"
                     /translation="MKKFTLGVALLTIGAVVLPSTTIVYASENSQVVSLNENNATENV
                     VIEYTEDGMVVTKYEDGYSAEDFANSSDIMTRAAVARWGKKEYTNIAVTTGVAANAIN
                     AAFWAGGKASTSMFGIPGWAIGALLTGASWTKKGASPGNAVAKEWDKNGNGWIGFYYQ
                     RGYDAAGRVVATRYSTL"
     gene            4495..>4686
                     /locus_tag="ACF3UE_002574"
     CDS             4495..>4686
                     /locus_tag="ACF3UE_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635916.1"
                     /translation="MFLISKSLKSLKTFTKKNPQIATIRIFIFAIAVAIIVNMLSGGQ
                     LYKSGLFLVLILVVLDIIKS"
BASE COUNT         1724 a          703 c          841 g         1418 t
ORIGIN      
        1 aaaaaaaaat aaatcgatac attttagaag aatagggttg tttgaatatt acaaagcaac
       61 aatttcacct tcggtgaaat aagcgaaact ttacaaaaag tggctagcaa atgctagcct
      121 ttttttgtat tgtggagcgt ggattttgag ggggattcaa gggggagctt gcgctccttt
      181 gacaagcggt tatttgcacc aaatacggag gtatttggct agcaaatata gagcttgcca
      241 aaccctttta gtgagttttg tagaaagtac ctttaaaggt actttcacat tacgaacgat
      301 acgtccgtag gacgtactga aagggtggga cttatgagca aattaatgca aaatttggct
      361 agcaaaaaag ctaaaaaata tatgctaata atcgagcgaa ataaacactt tttcaagtga
      421 gcgaatccgc catgacaaag ctgaagcagt ttatttcagc tttgtcatgg cgtgtgccga
      481 cttttttaaa agtctaggca cacgagcaaa tatctttatc aagctctaat ttgcgtttta
      541 agacgtttga aacgcctaag tatataaata tataagaata ggtttaagag tgcttaaatc
      601 gaattttaga gggcatttag acaattttag ggttgttagg gcttgccctg accgcctgta
      661 aggcgtttta agaacaagat aagggattta tactaggact gtcttaaaat gtcttaaacg
      721 aacgctcaga gcttctcaaa gggttcctta tgaacggctt ttagcaaagg agccggaggc
      781 gactgcgcag tataatgtga gagcagagcg atcacacctt tttagcgaac cgtagggagc
      841 aaggtttgga attggcagtt ttgataaatt cgcgaacctg tttagagaaa aaaggagtga
      901 ttttttaggc gggaaaatta gcctcccctc tttttatatc tctttttata tctcttttta
      961 tatctctttt atgtcggctg tgtccttact ctcccaagca attcagagtt ttttcaagta
     1021 ggttttctac gcttttcaag taggttttct acgcttttca agtaggtttt ctacgctttt
     1081 caagtaggtt ttccgacatt attgagtatt tttataaagt atgttacttt tatttcatac
     1141 tttataaaag taggagaagc ttatggcaaa tgaaattgta aaatatgaaa atagattaaa
     1201 tcatattcct ctgagaaaat ttaatagtcg tgaaatgaac ttattttttt caattgcttc
     1261 acgtgtacgt gaaaaaggtg tagatgagat tattttttca tttcacgatt tgaaaaaact
     1321 aagcggttat acagaacgtg gggaacaatt tataaaagat cttagtagca cgtatgacaa
     1381 attattaagt attaatgctt ggaatgatga tggaaatact ttaactaaat ttgttgcttt
     1441 cacaaaatat agcattatac gagataaaca acttgttata atttcagtta atccagaatt
     1501 taaaggactt tttaatcaat taaagaactg gacaagattt aatctagagc aatttactaa
     1561 tttggatagc acatattcaa aaactatgtt tcgattatta aaacaatatc gaactcaagg
     1621 ctggactgaa ttttccaaag aaaaattttt tgatttacta gatattccta aaagttattg
     1681 gaatagtccg tcaaatattg acaaatttat cttaaggcca attaaagaag aactcactcc
     1741 cttatttaaa ggattaacta ttcgtaaaaa atatggtaaa ggtcgaggta aacctgttat
     1801 cggttatcgt tttacttgga aagctgaaat taaccatgct gacgattttt ccaaagggaa
     1861 acaagaagat ttacgtataa aattatttaa tattgatcac aatggagaat taacacgaga
     1921 agaaaaatgg cgcgctaaag atcgaatact aaatcttccc ttaggcactc atgaagctga
     1981 ttttaaacaa caacaacaaa ctgaagaaaa acaggcagaa aaacgagaac tttcaaacaa
     2041 actcaaacaa gatttactag gaaatttaca aaacttattc gattaagctt aaggagtatt
     2101 tatggcagat aaaacaatca aagaacttgc ggaagaatta ggagttagta aaacagcaat
     2161 taacaaaaaa gtttctgaca aaaatcgaaa actttggttt gcaaaaaacg gaaacaagtt
     2221 tgtgattaac gaaaccggtc aaaaagctat aaaatcaatg tttttagtcg ataacgcaaa
     2281 cttaaatcga aaactagttg gcgaaaaatc aaaaaccaaa aaccataaaa acaccaacca
     2341 agtttccgaa ttaaaactcc tttctttcct agaaaaacag ttaaatcgaa aagatataca
     2401 gctacaagaa aaagataatc aaataaaaca aatgcaaaaa ttactcgacc agcaacaaca
     2461 actcactcta caagcgaacc aacaaattga gaacctacaa gaacagctcc atttaactta
     2521 tacagaagaa actccaacaa ccgaatcaac tgccttttct gaaaaaaaag cagacaatac
     2581 acaaccactt attgaaaaaa agtggtggca aatttggaaa tctaatagaa ccaatctcta
     2641 aaattttcta gaagttagtt cggatagtag aggaaaaagt tgtactacct gatggggaga
     2701 tcactcaaat ttttatgaga aagaaaaaat agtttacaac tgtaaacaat caatgtttat
     2761 agttgtaaac tatcaaacta tatggtgact tattgcttaa aataggttga aatctcactc
     2821 aatttttggt ggaaaaacaa aataaattct aatcgatttt gttgaaaaag tcataaaaaa
     2881 acaaatgtga ttttaacaaa atttcaaaaa aatcgtttga aatttcgttt attttttttg
     2941 agaattttga tcatcgtagg gtcattgtag aatcattatg agatcatcgt gggatcatcg
     3001 aataaagtat gggaaaggct tgcggtgctt ggtattaagg gcattctccg cctcccaggt
     3061 tcttgaccat tttctctcaa cgtggtaaaa atcccactta taagagaaaa tggtcaagaa
     3121 cctaaacggt cggcgaagaa aacataccaa gcaccacaag caaaaaaagt tagagtaact
     3181 tccaaaaaag aaaaattttt tagaacaact tttgaaaatt taattttgat ttatatccgt
     3241 tcaatttaaa catttgataa actgaaggct agtatttaaa atgtgtatac aagtggtagc
     3301 gttaaaaaaa gtggaggtat aacctatgtt aaaaaaaact gtgttggtac tgggttctat
     3361 ttctctagga atattaggtt ttagccccat gctattatcc gtaattggaa aaaacaattc
     3421 caacggagaa cttaaattaa attcaaatta ttacaacagt cctaacgaag aattgtttgt
     3481 aaaagagacg gataaataat aaaaaagact gctctttcga gcagccagtt aaaaaataat
     3541 gagtgtttat tcttgaaaaa gcaacgcgct tatgaagcgc taccaaaaat ttatcatatt
     3601 ttatgaaaaa taacacccca gtaaaaaatg actggtaaaa attcacaaag aaacggaaag
     3661 aagcaactgc agaaaatcaa gccttaaaaa gagcttttga cttagaccaa tcgaaaatca
     3721 caaagtgagc ccctgtatcc cttggtagag aggctacttg gcatagtaca cattatgtca
     3781 acaagaattt aatataacat attttcctaa tgcattctaa ctataccaca ttatcaaaaa
     3841 tataaattat ctttactaaa taaaatattg acaagcctat accttttgtt ttatgatttt
     3901 cacaaagaaa acgttttcta tatatttttc tgtatcagga ggaaattcta tgaaaaaatt
     3961 tactttaggg gtagctttgt taactattgg ggcagttgtt ttaccgtcaa ctactatagt
     4021 ttatgcttca gaaaattccc aagtggtatc attaaacgaa aacaatgcta ctgaaaatgt
     4081 agttattgag tacactgaag atggtatggt cgtaactaaa tatgaggatg gttatagtgc
     4141 ggaagatttt gcaaattctt cagatatcat gacaagagct gcagttgcaa gatggggcaa
     4201 aaaggaatat acaaatattg ctgtaaccac tggagtagct gctaatgcta ttaatgctgc
     4261 cttttgggca ggagggaaag ctagcacttc tatgtttggt atcccaggtt gggcaattgg
     4321 tgctttgtta acaggtgcaa gttggactaa aaaaggtgct tctccaggga atgcagttgc
     4381 aaaagaatgg gacaaaaatg gtaatggctg gattggattt tattaccaaa ggggatatga
     4441 tgcagctgga agagttgtag ctactagata ttcaacgtta taagttaagg agtgatgttt
     4501 ttgatatcta aatcattaaa atcattaaaa acatttacta aaaagaatcc gcaaatagct
     4561 actattcgta tttttatatt tgctatagct gttgctataa ttgttaatat gctaagcgga
     4621 gggcaattat acaaatctgg tttattttta gtgttaatct tagttgtctt agacataata
     4681 aagtct
//
LOCUS       DAXLPC010000126         4666 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.129, whole genome shotgun sequence.
ACCESSION   DAXLPC010000126 DAXLPC010000000
VERSION     DAXLPC010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.129"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            287..694
                     /locus_tag="ACF3UE_002575"
     CDS             287..694
                     /locus_tag="ACF3UE_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635917.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            708..1109
                     /locus_tag="ACF3UE_002576"
     CDS             708..1109
                     /locus_tag="ACF3UE_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635918.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1111..1482
                     /locus_tag="ACF3UE_002577"
     CDS             1111..1482
                     /locus_tag="ACF3UE_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635919.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1518..1820)
                     /locus_tag="ACF3UE_002578"
     CDS             complement(1518..1820)
                     /locus_tag="ACF3UE_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFD3635920.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2078..2191)
                     /locus_tag="ACF3UE_002579"
                     /pseudo
     CDS             complement(2078..2191)
                     /locus_tag="ACF3UE_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(2574..3807)
                     /locus_tag="ACF3UE_002580"
                     /pseudo
     CDS             complement(2574..3807)
                     /locus_tag="ACF3UE_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
     gene            4064..4330
                     /locus_tag="ACF3UE_002581"
                     /pseudo
     CDS             4064..4330
                     /locus_tag="ACF3UE_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            complement(4333..>4666)
                     /locus_tag="ACF3UE_002582"
     CDS             complement(4333..>4666)
                     /locus_tag="ACF3UE_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3635921.1"
                     /translation="ESVPKNLFKSITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQR
                     GLNENSNGLLRRDGLLKSMDFNSVDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVS
                     IDDLSNLI"
BASE COUNT         1565 a          775 c          820 g         1506 t
ORIGIN      
        1 tgaggggaag tacatatagt tgttgatata gttgctaata ttgttagcta atttgttagt
       61 aaaactgtat acgaatttag atagtaaaaa aacagtttgt tccttatata gaggcacttt
      121 tactactgat taaatgtcag atatgcttac aaatatactt ataaatatgc ttacaaaatt
      181 agctaatatt tccgttgaca aagctttgtt actattgtta aactaaattg actagcaaaa
      241 gtgaaacata aatttattaa ataaatgtaa aaattaggag aaatcaatgt cttatagagt
      301 acaattaata atttcagaag atgtagaaag tcagcaattt ggcactaatg ttattaataa
      361 agtaattaat ccagctcttt ctattaatgc gcctttaatt cctactgctt tatcattttc
      421 tgtaacagct gtggtgtctg agatagagga tacagaaaag ataaaaatag tagaaattga
      481 agttttaaac aagaatgaaa aacaaatttt ttctacgggt gaagtatcgg taagcttgcc
      541 tcctcaagtt aacgatataa actttaatat aaacgccaga aatgtcttgg ttgaagaagc
      601 aggagagcat tatgctgttg ttaaatttaa tggaactgag attggaaggc aaatctttga
      661 tatcaaggtc aacaaaccag tggaaaaaaa ttaaggagac gatacggatg cttgatatag
      721 taccatcaaa tacacatcgg agtggtagct taataaattt tgctgcgatt tttgcttgcg
      781 catcggtaat tctagcatct ccagttgttg tggatgcaag ttctactccg aaaactaaaa
      841 atgataatca acttgtaatt actacaaaaa atgagattaa cacaatttca agtaatgatg
      901 gcaaaatttt tgatgtgata aatacggttt taaaaagaaa agctgaaatc aatataaaat
      961 atgatgaaga tttaaacttg tatttctttg ttatcaaaac aacatctgaa ttgttttcct
     1021 cagattacga tgttttggat actctcgata atgtattatc tgactataaa tatatgggga
     1081 aatctgtagt agcaactttg ggggaataaa atgtttgact ttaatgaata tttatctatt
     1141 tccaaacaaa ttgaatcaga tgataaatat aattctaaag aatcttatag aagaactgct
     1201 gtttcaagag catactacag tgcttttaaa aaatctgatg agtatttgaa agaaaattat
     1261 gatattattt ataatggaag tagcggaaaa ggaagccacc aaaccgtttg gaatttgttt
     1321 tcaacagtta aggaattgaa taccttagga atacataata gtgggtatag aatgttagag
     1381 aaaagaaaat gtgctgacta tattcctaat gaaaccatta cgaaaacaga tatggcgctg
     1441 atgaatcgag aagcagaaaa aataataaac aaactcacct aatgaatttc aagcgagttt
     1501 gtttgttatt tttttattta atctttgtat ctttctggat caacgaaagt atactttata
     1561 tagtcataac gccgatgatc gctacgtgcg tccggcacgt cagtcacgat atcaaacaaa
     1621 aagtatacac ccttcttcat tctagttttc gcagcaggaa ttttgaaata gttcttatta
     1681 gaatagtaga gattgattaa taagctatct tcgattgcta aaaagaaaac ttctgaattc
     1741 catactttat aaaaatcttt gataaatcta ttcgaagggt caaatttaaa ccataattgt
     1801 gtttttcctt ccatcagcat aaaagttcac ctcaaaaaga gtatacgaac gaatgttctt
     1861 tttgtgaagg cggaatttaa tatactgaat aatagaaaac aagtacttgt gccaaattat
     1921 gtgccaaaaa aattcgaatt caacaaaatg taaacaaata gaaaaccttc tatattaaga
     1981 tttcctgcaa taacaaacac aacagaagac gtgtaatagt tagtcaggaa cgtacaaata
     2041 acccctgtat cctttgcggt acagggggtt attttgtata agtagacatt gtagtttcta
     2101 aactgctatg tcctaaacgt ttcgatacgc taagtatatt tactccttga taaagtaaaa
     2161 tagatgcatg cgtatgtctt agtccctcaa taaacagtcg aagagaaaat aggcaaaaat
     2221 tgattactaa agaaaaactt actaggtcga cggtgtagtt gattttcata cttcaacaga
     2281 ttcgaattaa acgatttcga ttggcttata ccagtcctat ccgacgaaag atatatcgtt
     2341 cttaactcta gcggtataac ttgaagcttt acgtaaagcc aatgggaatg aactggagat
     2401 gactttttat tatttttagt aatagctgat gggttaatac ttacaacttt ccttttcaaa
     2461 gtaccatata aaaaaacggt ggggttgttt agcgaaataa aggatctaag ccaatagctt
     2521 agatccttta ttctatgctt tatattattt tttgcatgtg tgcgaaagta tactcaagcc
     2581 caatcgccat ttcggaaaat cggtactgta gagccatctt cacggattcc gtcgatatcc
     2641 atcttgtcag atcctaccat gaaatctacg tgggtttgac ttctattcaa tccagcttct
     2701 gctaattctt catcggacat ttctgtaccg cctttcacac tgaaggcata agcagaacct
     2761 agtgctaagt gattcgatgc gttttcatca aataatgtat tgaaaaagat gatgccagat
     2821 tgagaaatag gtgaagggtc aggtacaagt gcgacttctc ctaaacgacg cgcaccttca
     2881 tctgtatcaa gcagttttgc taagacatct tctccttgtt cggcagaaaa atcaatgact
     2941 tttccatctt taaaagtaaa tttcataccc gagatgatgg tgccagcata actcagtggc
     3001 tttgtacttg aaatgtaacc atctactcga tgactgtcag gtgctgtgaa cacttcttcc
     3061 gtcggcatat ttgccatgaa tttttctcca cgagcattat agcttccagc gccttcccaa
     3121 agatggtttt taggcaatcc gataatgata tctgtaccgg gagcagtata gtgcagggca
     3181 gaaaattgtt ctcgattcaa ttcttctgct ttttttgcta atttttcatc atgcttcttc
     3241 catgctaaga cagggtcttc ttcatagaca cgagtcgttt tgaaaatctg atcccataat
     3301 gcctcaactt gtttttcttc tggcagttct gggaagactt ttgctgccca ttgtttacca
     3361 gccgcagcca cgacagtcca actgacttta tttgcttgag ttgccttgcg taaattcatt
     3421 agtgctttgc cagccgctga ttgataagac ggctactcga tggctatcta caccagcaaa
     3481 tgcatcggga tcggcagaaa caacactgat cctgcttgct cctttttcaa gccattcatc
     3541 cgcttgatcg attttagatt gtggtacatt ctcaatacga tccgttgcag catgtaaaag
     3601 aaattctctt tggatctggt cgtcagtcca ttgaacgata acctcagcgg ctcctagttt
     3661 ataagcttct tgtgtgatca atcgagcaag gggtgcctgt tccacgctga tctgtaaaac
     3721 aactgtgtgt cctttttctg tggctacgcc agtttctgca attaagcgtg catatttttt
     3781 tagaagttca ttaaaatcag ataacataat aaaaattcct cctcaccatt ttttctggta
     3841 actattagca tgataccatt taattatgat tcaaacaatg aggcctttaa ataaaaaaaa
     3901 gaggttattt ttttaaggtt aagtttcatg atatatgtta ctacttgcta tttcagcttg
     3961 tgaagaaaat caaaaactaa ttttgcatat caaaaaaaac atgttacaat gaaattaatc
     4021 aatggtggaa gcgttataaa aaaattaagg agattaaaaa aatatggcaa gaaaaaagac
     4081 gattactaga gaacagattt tggcagctgc ttatgaagta gctgccaccg atggatttac
     4141 acgatttact gcgagaaaca tcgcgaacaa aatgaattgt tccacgcaac cgatttatct
     4201 tgagtttaaa aatatggatg acttgagaca agctcttttt gagcagatct atgatcattt
     4261 acaatatgaa gtgttcactg ttgagcatac agggaatacg attatcgatc ttgcttttaa
     4321 ttatcttaat tgtcaaatta agttagacag atcatcaata cttacgtaac tcaaaaatac
     4381 ttccaaaggt gttcgataat ccagtgattt tctaggaata ttatttcgtt tagatgcgac
     4441 agattgaata aaaaattcat ctactgaatt gaaatccata gatttcaata aaccatctct
     4501 acgtaacaat ccgttagaat tctcgtttag gcctctttga gacggcgttc ctggatcagc
     4561 gaaataaatg gcaatatcat tgacattact gatctgtttc caatttgaaa attcctttcc
     4621 acaatcaaaa gtgatggatt tgaataggtt tttcggtaca gattca
//
LOCUS       DAXLPC010000127         4646 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.130, whole genome shotgun sequence.
ACCESSION   DAXLPC010000127 DAXLPC010000000
VERSION     DAXLPC010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4646
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.130"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..127)
                     /locus_tag="ACF3UE_002583"
     CDS             complement(<1..127)
                     /locus_tag="ACF3UE_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3635922.1"
                     /translation="MNYIYLIKEHYPLLTKSEKKVADLILDSGKAIIYSTMSDIKE"
     gene            290..997
                     /locus_tag="ACF3UE_002584"
     CDS             290..997
                     /locus_tag="ACF3UE_002584"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFD3635923.1"
                     /translation="MKKQIFLDAISGGLIVSCQALPGEPFYKEEGGLMSYFALAAERA
                     GAVGIRANSVRDILEIKEKVSLPMIGIIKRDYPPEEPFITATMREVDELVATGVEVIA
                     LDCTLRKRHDNLSINTFITQIKEKYPEQLLMADISTFEEGKNAYEAGVDFVGTTLCGY
                     TNESRKQEGPAIDLMKQLVQAEICVIAEGKIHTPEQAKKIRELGVSGIVVGGAITRPQ
                     EIAERFVNALKEEEKNV"
     gene            990..2492
                     /locus_tag="ACF3UE_002585"
     CDS             990..2492
                     /locus_tag="ACF3UE_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFD3635924.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPIL
                     AQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVSYLVYTATI
                     SGFLELFSVKDATLDTGVVGSIAIGGIVAFLHNRYRKIELPQFLGFFGGSRFIPIISS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEHIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTESVAGITVSGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGLAWAIIYFIVFTFFL
                     KKFKVAIPGMIEEKEVVSEINLNKNTSLHEESLMIIKALGCEENIESVEACATRLRVA
                     VKNGQNVDKQAIKQLGATAVFEVKGGIQAVFGGKADLLSQEINQILKRDN"
     gene            2504..2983
                     /locus_tag="ACF3UE_002586"
     CDS             2504..2983
                     /locus_tag="ACF3UE_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFD3635925.1"
                     /translation="MIKFLRKKKQVELFSPCSGKVIPISEVNDPVFSQKLLGEGFAVI
                     PEEQTIYAPLAGQVTTIFPTKHAISIKSNSGIDYLIHIGIDTVELEGKPFSILVDEKE
                     YITPENPLVKVDFKQLELAKKDSSVIICFTESSQIDNLDLYTGRVLHGVLCGYLNLS"
     gene            complement(3575..>4646)
                     /locus_tag="ACF3UE_002587"
     CDS             complement(3575..>4646)
                     /locus_tag="ACF3UE_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFD3635926.1"
                     /translation="KITSLNKASVSSIINKLIDDSLVIENRIGEATNRGRKPIMLTFN
                     GVSSGLAIAIDLGYNYIDGMVASLDGKEIARIQLTDTYVSKDNIQMLIRKIIKKLTDN
                     LPYTRHGIIGMTIAVQGQVLNNKVLSTTYNGLEEIDLVKLLNQEYSFPVFLQNEANLS
                     ALGEYTFSSDIENLVSISLHSGIGVGVVKNGKLDIGNKGYAGQLGHTILFPNGRKCEC
                     GNYGCLEKYCSTQVIYQEISKEKKLDKINSDIVEYLYSNKDQKVVEMIELYAYYLSIG
                     INNIVMLYAPELVIFNSPLTKKIPNIINIIKNFLNNQYTKEIHIINSPIEWNPVLSGA
                     ISFSIQKFLNIEKLKLSSYAKN"
BASE COUNT         1479 a          681 c          840 g         1646 t
ORIGIN      
        1 tttctttgat atcgctcatt gtactataaa taattgcttt cccagaatct aagattaaat
       61 cagctacttt tttttcagat ttagtcaata aaggataatg ctctttaatt aaatagatgt
      121 aattcatatg aactccttta cagtaaaaaa ttttactcca ttatactcca aaaagataaa
      181 aaaatctcca aatttatcca tttttatact ttacatcaat gaaagcgcgt gctatatttt
      241 atttggagtt attatccgaa aattaattta aagtggagtg tttaggagaa tgaagaaaca
      301 aatattttta gatgcaattt caggtggact gattgtttct tgtcaggcat tacctggtga
      361 accattttat aaagaagaag gaggtcttat gtcctatttt gctctagctg ctgaaagagc
      421 tggtgcagtt ggtatccgag caaattctgt tcgagatatt ttagagatta aagaaaaagt
      481 ttctctacct atgattggga taattaagcg agattatcct cctgaagaac catttattac
      541 cgcaacgatg cgtgaggtcg atgaattagt tgctactggt gtagaagtta ttgcgctaga
      601 ttgtacgctg cgcaaacgcc atgataattt gtctatcaac actttcatta ctcagatcaa
      661 agaaaagtat cctgaacaat tattaatggc agacatctct acctttgaag aaggtaaaaa
      721 tgcctatgaa gctggcgttg attttgtcgg aaccacgtta tgcggatata ctaatgaaag
      781 tagaaagcaa gaagggccag cgattgactt gatgaaacag ctcgttcaag cagaaatttg
      841 tgttattgca gaaggaaaaa tccatacccc agagcaggca aaaaaaatta gggaattagg
      901 tgtttctgga atcgtagttg gtggcgcgat cactcgtcca caagaaattg cagaacgttt
      961 cgtcaatgca ttgaaggagg aagagaaaaa tgtttaaaaa attttcacaa ctaggtcggg
     1021 catttatgtt gccgatcgct attttacctg ttgctggttt acttttaggt cttggcggtg
     1081 cactgacaaa tgaaagcgcc ataaatgctt atcccatatt agctcaaccg tggcttcata
     1141 cgattttgag tatcatgagt tatgctggta acgccgtttt tgctaattta gcattgatat
     1201 ttgcgattgg tatcgcagtg gggcttgcaa atggtgacaa aggaactgct ggtttagctg
     1261 gtggtgtttc ttacttagtt tatacagcaa caattagtgg ttttcttgaa ttattttctg
     1321 tcaaagatgc aactcttgat actggagttg taggttcaat tgccattggc ggaattgtcg
     1381 catttttaca caatcgctat agaaaaatag aattaccgca gtttttagga ttctttggtg
     1441 gttcacgttt tattccaatt atttctagtt tggctgcaat tattattggt tccttctttt
     1501 atctaatttg gccaccgatt cagaatggat tagttgttgc tggagagcat attgctcaaa
     1561 tggggagtct aggaacattt ctttatggat ttttacttcg tttaactggt gctgttggtc
     1621 ttcatcatac aatttatcca cttttctggt acacttcgtt agggggaact gagagtgtag
     1681 cgggaattac agtttctggg gcacaaaata ttttctttgc tcaattagct gatccgaatc
     1741 acacaggctt atttacttat gggactcgtt tttttgctgg aagatttgcc acgatgatgt
     1801 ttggccttcc tgctgcttgt tatgcgatgt atcgtgcaat tcctaaaaaa aaccgtaaga
     1861 aaaatggcgg tctttatttc agcggtgcat taacttcgtt tttaacagga atcactgagc
     1921 ctgtagaata tatgtttctg tttgtggctc catggcttta tgtcatccat gcatttttag
     1981 acggcctatc tttttatttt gcggatatcc tgaatattcg agtaggaaat tctttttcag
     2041 gtggactaat tgattttcta ttatttggtg tacttcaagg aaatgacaaa actaactggc
     2101 ttaaattgat tccttttgga cttgcttggg ctattattta ctttatcgtt tttactttct
     2161 ttttaaaaaa attcaaagta gcgatccctg gtatgataga agaaaaagag gtagtctctg
     2221 aaattaactt gaataaaaat acttctttgc atgaagaatc tttaatgatt ataaaagcac
     2281 ttggctgtga agagaatatt gaatctgttg aagcctgtgc aactcgcttg cgtgttgctg
     2341 tgaagaatgg acaaaatgtt gacaaacaag ctataaaaca attaggtgct actgcagttt
     2401 ttgaggtaaa aggtgggatt caagcagttt ttggaggaaa agctgattta cttagtcaag
     2461 aaatcaatca aattttgaaa agagataatt aggaggaatt tatatgatta agtttttaag
     2521 aaagaaaaaa caagtggaac tattttctcc atgttcggga aaagttattc ctatatcaga
     2581 agtaaatgat ccagtttttt cacaaaaatt attaggggaa ggttttgctg ttattccaga
     2641 agagcagaca atttatgctc ctttagctgg tcaggtcaca actatctttc caacaaaaca
     2701 tgctattagt ataaagagta attcaggaat tgattatttg attcatattg ggatagatac
     2761 agtagaatta gaaggaaaac ctttttcaat tcttgttgat gaaaaagaat atataacacc
     2821 tgaaaatcca ctagttaagg ttgattttaa acagcttgaa ttggctaaaa aagactcatc
     2881 agtaatcatt tgttttactg aatctagtca aattgataat ctcgatttat atacaggaag
     2941 agttttacat ggtgttcttt gtgggtattt aaatttatca taatgattaa tagttagatt
     3001 aataagatct aattattaga aactcattgg tgaagtttta gagtttaaag aagtagtata
     3061 taagttgtaa ctttctcaat gtataataat tttgattgac aagagattaa tgtgatagtt
     3121 ttgaaaaatg aaatatgatt ggagtgaacc tcgttttatt aagtttttga ttatatgatt
     3181 ttagtcagct cgcccacgtg tagaaacaaa aagatatacg tttctatacg tgggcgaagc
     3241 tgtttttact tttaatagcg ataaaagttt agtatataat ttagatgaaa ttgtaaaatt
     3301 ttaccctaaa gtataggcca aatggataat aagcaagcat gctttgatta aacaaaaaga
     3361 caattgaaaa aaattgagaa tatttgatag attattgagt tagaaatagt ttaagtaata
     3421 agcattgtat taattttttt atctcttgaa aaagaggtag agcggtgaga aattcataac
     3481 tatataaaaa gctcttttta aggagagagt actggtgagc cgtctagtat gttaaaattt
     3541 ctccatttca catactagtt tccactaaat taaattaatt ttttgcataa gagctgagtt
     3601 tcaacttttc aatatttaaa aatttttgaa ttgaaaacga aattgctcca ctaagaacag
     3661 gattccactc tataggactg ttaatgatat gaatttcttt tgtatattga ttattcaaaa
     3721 aatttttgat tatattaatt atgttcggaa ttttttttgt taaaggactg ttaaaaatca
     3781 ctaactcagg agcatagagc ataactatat tgttaattcc tatcgataaa tagtatgcat
     3841 atagttcaat catctctaca accttttgat ccttgttgct ataaagatat tccactatat
     3901 ccgaattaat tttatctagt tttttttctt tggaaatctc ttggtaaatt acttgagtag
     3961 agcaatattt ttctaaacaa ccataattac cacattcaca ttttctgcca tttggaaata
     4021 gaattgtatg tcccaactga ccagcatatc ctttattacc aatgtcaagt ttaccatttt
     4081 ttactactcc aacgcctatt ccactatgaa gactaattga tactaaattc tcgatatcag
     4141 aagaaaaagt atattcacct aatgcagata agtttgcctc attttgtaaa aaaacaggaa
     4201 agctatactc ttgatttaat aattttacta gatcaatttc ctcaagaccg ttataagttg
     4261 tactaagtac tttattattt agaacttgtc cttgaacagc aattgtcata ccgattattc
     4321 catgtcgcgt ataaggaaga ttatcggtga gtttttttat aattttacga attaacattt
     4381 gtatgttgtc tttactaaca taagtatcag taagctgtat tcttgcaatt tcttttccat
     4441 ctaatgaagc taccattcca tcaatgtaat tatatcctag atcaattgca attgctaagc
     4501 ccgaagatac tccattaaaa gttaacataa tgggttttcg gccacgattt gttgcttctc
     4561 caattctatt ttcaattaca agcgagtcat cgatcaattt attgataata gaagatacag
     4621 atgctttgtt taaagaggtt atttta
//
LOCUS       DAXLPC010000128         4626 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.131, whole genome shotgun sequence.
ACCESSION   DAXLPC010000128 DAXLPC010000000
VERSION     DAXLPC010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4626
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.131"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            57..1118
                     /locus_tag="ACF3UE_002588"
     CDS             57..1118
                     /locus_tag="ACF3UE_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFD3635927.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            1121..2017
                     /gene="murQ"
                     /locus_tag="ACF3UE_002589"
     CDS             1121..2017
                     /gene="murQ"
                     /locus_tag="ACF3UE_002589"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFD3635928.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            2031..4013
                     /locus_tag="ACF3UE_002590"
     CDS             2031..4013
                     /locus_tag="ACF3UE_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFD3635929.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(4078..4524)
                     /gene="nrdI"
                     /locus_tag="ACF3UE_002591"
     CDS             complement(4078..4524)
                     /gene="nrdI"
                     /locus_tag="ACF3UE_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFD3635930.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
BASE COUNT         1499 a          821 c         1046 g         1260 t
ORIGIN      
        1 ttagatatat actctagtca tagaaatgaa gacggataca gaaaaagagg gataatatgt
       61 ttggcttttc aatatttatg aacgattctt tgtcagaaga gaagaaacag tatatccgcc
      121 aaatggcatc caatggcttt gtcggtattt tcacttccat gcatatacca gaagatgatg
      181 tttcggcata tcaaaagcga ttgatcgaac taggaagcga agcgaaaaag aataaactag
      241 aattgatggt cgatatttca ggagaggcat tggaacgagc gggtttttca ttagaagatc
      301 taacgccttt gaaagcaatt ggtgtaacag gtttaagaat ggattatcat atttccaatc
      361 agcagattgc cgactggtca catcaattga aaatcagttt gaatgctagc acgatcacgc
      421 ctaaagatat cgatgaattg aaagaagcag aagctgattt ctcacagatt gaagcttggc
      481 ataattatta tccacgtccc gaaacagggc tggacaaaga atggtatcag aaaaaaaatc
      541 aatggctcaa aattcaaggt ctccttgtcc aaggttttgt accaggagat acagagttga
      601 gaggcccact atatcaagga ttgccaactt tggaagaaca tcgagggatc catcctcttg
      661 caggcgctct agatctatta gcaagtaaca cggatattgt ttacatcgga gatgcaggtc
      721 tgtcagaaaa cgttcaggag caatttgctt ctttccaaaa agaacagaca gtcttgctcc
      781 atacggaacc tgtagatgaa gaattttacg aatatatatt agggaagcat acgaatcggc
      841 aagacgatgc aagagatgtc atacgaagcg tagatgcacg ttttcgagag attccgccta
      901 tcccagcaag aaatacagct acgcgtatga aagggtctat tactttagat aacgaaaagt
      961 atttgcgcta tatgggtgag atccaattaa ccaaatatga tttgccagcg gatgaaaaag
     1021 tgaatgtagt agctaaagtt atcaaagaag agctaccatt gatcaaccaa atcaaagctg
     1081 gtatgaacta tcaatttata agaaaagaag gaagataaaa atgagcaaaa tcaatttaga
     1141 gaacctaaca acggaacgca gaaaccaaga aacttttgga ttagatgaga tgagtatttc
     1201 tcaagccgtt caactaatga acaaagaaga tcagaaagtg gccgctgcgg ttgaaaaaga
     1261 actgacaagt atcgaaccag tgattgctaa cacgattgag tcctttaaaa aaggtggacg
     1321 tctgatttat atgggagccg gaacaagtgg aagactaggt gtgttagatg ctgctgaatg
     1381 cgtaccgaca ttcggtgtag aaccggaaat ggtcataggt ctaattgctg gtggagaaga
     1441 agcaatgact gtagctgtcg aaggggccga agattcttat gagctagggc aagaagatct
     1501 aatcaagctg aatttgacaa aaaatgatat agttattggt atcgcagcta gcggtcgtac
     1561 accatatgtg atcggtggat tagattacgc aaaatcgatc ggtgctgtca caggaacgat
     1621 ttcttgcaat aaacaagccg aaatcagtaa acacgcggat ttcccaatcg aagtcgatgc
     1681 aggtccagaa tttttgacag gctctactcg attgaagtca ggaacagcac aaaaacttat
     1741 cttgaatatg atttctacta tcagtatgat tggtataggt aaagtattca ataacttgat
     1801 ggtcgatgtc aaaccaacaa atgaaaaact aatcgaacgc tcaaaacgaa tcatcatgca
     1861 agcgacagaa gctgattacg aaacagctga aaagtacttt gaagaagcag atcaaaatgt
     1921 taagctggct atcgtcatga ttttgacaaa tagtgataaa gaggaagctc aagcaaaatt
     1981 agctgaagca aacggatttg taaaagggac cttatgaggg ggaaaagacc atggcaaaaa
     2041 acgaactgac tttggaagaa ctggcaaaac aaatttataa aggggcaggc ggcatgggca
     2101 atgtagaaag cattgtccac tgcatgactc gtgtgcgtat gaagatcatc aatgatgatc
     2161 ttgtaaatgt ctctgaatta aaagcgattc caggagtgct tggtgtagta gaagatgaac
     2221 agcttcaagt catcatcgga cctgggaaag tgaacaaagt agcacagcaa atggttgatt
     2281 tggcaggcgt gaaattagga gaaaaacttt cttctgtaag tacagctaca gcaaattcat
     2341 cagcatctgg aaaagaccgt gtaaacgaac gggcacaaga aatgaaagcg gcacaaaaat
     2401 cgaaacaaaa accatctaaa atcaaatcgg tattaaaaga catttctaat atctttgtgc
     2461 caatgattcc tgcatttgtc ggtactggga tcgtggcagg gattgccgca gttttagcaa
     2521 acttagtcac agccggaaca cttgatgcag caacatggca acaatatatc gatgtgatga
     2581 acatcttgaa aaacgggatg tttagctacc tagttatcta tacaggtatc aatgctgcac
     2641 aagtttttgg tgcaacacca actcttggtg gagttatcgg ggccgttgtg atgctgacag
     2701 ggatgaatcc ggaagcacca ctgaaaaact tatttactgg tgaagctctt gcagctggac
     2761 aaggtgggat cctaggtgtc atcttcgctg tttggctatt gtcaatcgtt gagaaaaaac
     2821 tgcataaagt agtacctgat gcggtagata tcatcgttac accaactctt tcattgattg
     2881 ccatcggtct gattgaaatt ttcttcatca tgcctttagc aggtttcatt tctgatggca
     2941 tggtcggtgg gatcaactgg gtacttggcg ttggtggagc atttgccggc ttcgttctag
     3001 gcacattatt cttgccgatg gttatgttcg gactgcatca aattttgact ccaatccatg
     3061 tgcaaatgat tgatgaaact ggtcgtacgc tattgcttcc aattcttgcg atggctggtg
     3121 caggacaagt gggtgcagca ttggcattat ggattcgctg caaaaaagat aaagaattaa
     3181 cagaaatgat caaaggagct ttaccagtcg ggatcctagg aatcggcgaa ccattgattt
     3241 acggagtaac attacctcta ggacgcccat ttattactgc ttgtatcggt ggaggtatcg
     3301 gcggggcagt gatcggaatg atcggaaatg tcggggctat cgctattgga ccttcaggag
     3361 ccgctttgat cccattgatc tctgacggta aatggttagg ctacatcctt ggattattgg
     3421 cagcttatgc tggtggcttc gttgctacat tcttcttcgg tattcctaaa gaccgtttag
     3481 aaaaagaaga attagcgact gaaacagcca cagtaaatga agtgcctgaa aaagtagtac
     3541 ctcaaacttc agctgaaagt gtgactatcc tctcatcagt tgctgacgga acagttgttt
     3601 ctttagataa agcaagtgat ccagtttttg cacaaaagat gatgggtgaa ggctactttg
     3661 tagaaccaga aaacggacat atctattctc cagttactgg ggtagtcagc tctgtcttcc
     3721 caacgaaaca cgctattggg atcacaacgc caaatggttt agaaatcttg cttcatatgg
     3781 gaatcaacac agttgactta ggcggtacgc catttgatgt gaaagtaaca gaagggcagc
     3841 aagtgacacc tgatacgctt gtagcagaag ctgacttaga agcgatcaaa gcagcaggca
     3901 aagaaacatc catgatcgtc ttggtaacca atatggatcg tgtaaaaaac tttgtcttgg
     3961 aaaaaacagg taaagcaaaa gcaaaagcac ctgtgatgga tgtcaaagct taatatgata
     4021 gaaacaatag aaacgaaaga agaaactgaa atctattttt cagcttcttc ttttttatta
     4081 tttattgttt tctgctaaaa tctgataaat tcgtgtcaca tcagatggtg ttccccgtaa
     4141 ttcataatct gccaagaaag gaaagccaaa tgtttgtgca tattgtttgg ctgttagaca
     4201 atactgatta ttgaagtttt tatttccgct accgactaca ccaagacaaa gtttatgatt
     4261 gtcttcatgt tccagatatt cacgcatcgt ttcggtcaag atttctgtat caccgttatc
     4321 taaaccattt ccgccgtcta aataagtagg aacgaaagta aaaaatggtt ctgtttcttt
     4381 cgtaaaatca ctattttcat ggatttcttt taaagtaact tcaggattga caggatcttc
     4441 tgcatgcatt ttttcagcat attctgctag atgtttggca aaggcacgcg tatttcctga
     4501 aatcgatata tataaaatgt tcatggatca tcctccaatt ctttcctttt agtatagcat
     4561 cttttttaag ttttttggtg gtgtaatttg gaaagggact aggcgctttg cttgtataat
     4621 gagaaa
//
LOCUS       DAXLPC010000129         4528 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.132, whole genome shotgun sequence.
ACCESSION   DAXLPC010000129 DAXLPC010000000
VERSION     DAXLPC010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.132"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            258..755
                     /locus_tag="ACF3UE_002592"
     CDS             258..755
                     /locus_tag="ACF3UE_002592"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HFD3635931.1"
                     /translation="MLFLRDGEIKATLTTMMNKLAFSHKLILEPLFKSVSQIDEESDR
                     ERMDAIDKLMEQLLEERNTLIALMSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTN
                     SASGVLRANEIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLK
                     EKVVR"
     gene            756..1172
                     /locus_tag="ACF3UE_002593"
     CDS             756..1172
                     /locus_tag="ACF3UE_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HFD3635932.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            1192..2736
                     /locus_tag="ACF3UE_002594"
     CDS             1192..2736
                     /locus_tag="ACF3UE_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3635933.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            2879..3103
                     /locus_tag="ACF3UE_002595"
     CDS             2879..3103
                     /locus_tag="ACF3UE_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635934.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            3118..3987
                     /locus_tag="ACF3UE_002596"
     CDS             3118..3987
                     /locus_tag="ACF3UE_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFD3635935.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDWINGGGWLFINGYHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3968..>4528
                     /locus_tag="ACF3UE_002597"
     CDS             3968..>4528
                     /locus_tag="ACF3UE_002597"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3635936.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKV"
BASE COUNT         1593 a          726 c          987 g         1222 t
ORIGIN      
        1 tttaaagtat tctgcttcat cacccattag gtgatgaaaa aagaacccct ttctgattta
       61 gcggacaaat actttgacct aatctcagaa gatataaaag aaaaaataat aaaatatccg
      121 atttatactt tgtataaaga actaaagtag ttagcaaatc atttacagca aatcactatg
      181 ttccacatac cattttacat acttacctta tccacgacac atgttgagat agtatcgaag
      241 ataaagaaag ttgctccatg ttgtttttgc gagatgggga aatcaaagcc acattgacaa
      301 ccatgatgaa taagcttgct ttcagtcata agctaatcct agaaccactt ttcaagtcag
      361 ttagccaaat cgatgaagaa agcgaccgtg aaagaatgga cgctattgat aagctaatgg
      421 agcaactatt ggaagaacgc aataccctta ttgcactgat gtccaaaggt ttcctagaac
      481 ctgctctttt taatcaggaa cgaaatgttt tagatagtga gattaaaaat cttactaccg
      541 aaaaaacaaa cctggtaacg aactctgcga gtggggtttt gcgagcaaac gagataaagg
      601 acctcattaa ttatgtgtca gcagataatt ttaatggtga ctacacggaa gaactatttg
      661 aagaatttgt agtgaacatc attgtaaatt ccagggatga gctgacattc aatttgaaat
      721 gcggtctttc cctgaaagaa aaggtggtga gataaatggc atatattcca tatggataca
      781 aaattcaaga tggagtggtt actgtcgatg aaaaggcagc aggtcaagta aaggtattct
      841 ttgagaaata catatcagga ctatccctta cagtggctgg cgaacaggca ggtattgaaa
      901 agacacattc tgtgatgggg cgcattttga aaaacgtcaa ctaccttgga aatgatacgt
      961 atccagcaat tattgataaa gagatatttg ataaagctga agaagttaga gataaacgtg
     1021 caaaggattt aggacgagtg gtagagcttg ccgctttcac ctctccccct cccaaagaac
     1081 gattcaaaat gaaaaaggca gataataaga tgccagtgga tccttttgaa cgagcagaat
     1141 acttatacag tctgatagaa agcgaggaat aaagtgacag agaaaaatat aatggttatt
     1201 cctgctcgta aaagagtagg aagtacagcc gcaaaagaaa agataaagaa acttcgtgtt
     1261 gctgcctatt gccgtgtttc tacagaaaca gaagaacaaa attctagcta tgaggttcag
     1321 gtctcacact atacagagtt tataaagaaa aataatgaat gggagtttgc tggcatcttt
     1381 gcagatgatg gtatctctgg tacgaacact aaaaagcgtg acgaatttaa tcgcatgatt
     1441 gcagagtgta tggacggtaa catcgacatg gttattacaa aatccatcag ccgatttgcg
     1501 cgtaacaccc tagactgcct tcaatacatt agacagctca aggataagaa catatcagtt
     1561 tattttgaga aagagaacat caacaccacg gatgccaaag gtgaggtttt gctgactatt
     1621 atggcatctt tggcacagca ggaaagccag agcctttcac aaaacgttaa gcttgggcta
     1681 cagtaccgat accaacaagg aaaggtgcag gtcaaccata agcgatttat gggctacacg
     1741 aaagatgaag atggaaattt aactattgtc cccgaagaag ctgagattat caaacgcatc
     1801 taccgagaat accttgaggg tcagagtcta gtgggcattg gtcgagccct tgaaaaggat
     1861 ggtattttaa cagcagcggg aaaaccaaga tggcgaccag aatcagttaa gaagatactt
     1921 caaaacgaaa aatacatcgg agatgccctt ctgcaaaaga ctgtcacagt agattttctg
     1981 accaagaaac gagtgaaaaa tgaagggcat gttccccaat attatgttga aaatagccat
     2041 gaagcgatta ttcctaaaga gttatttttg caggcgcaag aagaaattca tcggagaagc
     2101 aatatctaca caggagaagg caagaacaaa agaatttaca gtagcaagta cgctttaagt
     2161 gccatcacct tctgtggaga ttgtggcgat atttatagac gggtctattg gaatatccac
     2221 ggaagaaaag aatttgtctg gcgatgcgtg actagaatcg agcaaggtcc tgaagtttgt
     2281 aagaaccgaa ccgtaaaaga agatgaactt tatggtgcag taatgactgc gattaataag
     2341 ctacttgcag gtgggaacaa tatgataaag acactggaag agaatattca tgctgtgatt
     2401 ggcgaaacca cagaatacca aatttcagag attaacaact cactagagga aaaacaaaaa
     2461 gaactaatca agctggcgaa caagggtcaa gactatgacc acttagcaga tgagattgat
     2521 gagctgagag acaagcgaca gatcctttta gtagaagatg cctccctcag tggcgagaac
     2581 gagcgaatca atgagctgat tgaatttatc cgcaagaaca aattccgcac cttagaatat
     2641 gatgataagc ttgtaaggaa gataatccag agcgttacag tctatgaagg ccacttcgtc
     2701 atagccttca aatctggcat cgaaatggaa atatgaaaac cagaagtaaa tagcccatga
     2761 ctctacagta gagttgtggg ttttcttttg cttgctgatt ataataatat tttaataact
     2821 attgtgttta tcaaccaaat ggtttataat attcttagcg taaacttgga ggtgctgtat
     2881 gactacggca gaaatgatta aagaactgtg tgagcaaatg aatataagtg tttccgaact
     2941 tgctagacgt attggccaga ctccacagaa tttcaataaa aaattacaac gagaaacagt
     3001 aaccttggat gagttgaagg ccattgctga tgtgctaggt gtcaagtttg tgcaggcatt
     3061 tattttacca gatggagaag aaataaaaat atctaacgaa taaaggagga tgtttatatg
     3121 gtaggtaatg ttattcaaat agtaacagag aaattatcat ctttgccttt tatagaaggc
     3181 atcgtattag ggggctcacg tgcaagaggc acccatacag aaaattctga tatagatatc
     3241 ggaatctatt acaattcaga ctcatttgac ctgacagcga ttaatcaaat tgctacagaa
     3301 ttggatgata aaaatagaaa caaccttgtt gtgcctcccg gagcgtgggg tgattggatt
     3361 aatggcggcg gatggttatt tataaatggg tatcatgttg acttgatttt acgtgatata
     3421 aaacgggtag aacaaataat caaagatacg gagcaaggaa ttgttactgc caattatcag
     3481 accgggcatc cccatggtta tataagtgca atgtatcgtg gagaattagc gattagtaaa
     3541 atactatatg ctaagaacga aagcttatgc gaattaaaaa agcaggcaga aatttaccct
     3601 actgctctaa agaaaagctt gatgaacttt tttatatttg aagctgaatt ctctttaatg
     3661 tttgtaaaag caaatgcggg ggtagaggat aaatattata ttgcaggcca tgtttttcgt
     3721 attatttcat gcttaaatca agtactattt gcatgtaata atgcttattg cattaacgaa
     3781 aagaaagcta taaaactgct tgaaactttt gaatataaac ctgaaaaata tgccgaaaga
     3841 gttaatcata tttttgaagt actcggtctt tctctttttg aatgctacga tatgaccgag
     3901 aaactttata aagaagtgaa tgaaattgta tcggagataa ataacttttt aaacgaggag
     3961 agttcagatg aaagaaaaca aatatgatga taatatattt tttcaaaaat acagtcaaat
     4021 gagtcgctcg cagaaaggac tggctggtgc gggagaatgg gagactttga aaaagatgct
     4081 acctgatttt aagggtaagc gtgtgcttga tttaggatgc ggctatggat ggcactgtat
     4141 atatgcgatg gaaaacggtg cttcctctgt agtaggtgtt gatatttctc ataaaatgct
     4201 cgaagtagca aaaggaaaaa cccattttcc acagattgaa tatgaatgct gtgccataga
     4261 agatgtggat ttcccagagg agagctttga tgtaatacta agttcgcttg cgtttcatta
     4321 tgtagcagac tatgagaatt taataaaaaa gatatatagg atgctgaagg ctggtggcaa
     4381 tttagttttt acagttgaac atcctgtttt tactgctcat ggaacacaag actggtatta
     4441 taacgaaaaa ggagaaatac tgcatttccc ggtggacaat tattattatg agggcaaacg
     4501 gacagctatg tttttggaag aaaaggtt
//
LOCUS       DAXLPC010000130         4431 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.133, whole genome shotgun sequence.
ACCESSION   DAXLPC010000130 DAXLPC010000000
VERSION     DAXLPC010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.133"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            86..1507
                     /gene="gndA"
                     /locus_tag="ACF3UE_002598"
     CDS             86..1507
                     /gene="gndA"
                     /locus_tag="ACF3UE_002598"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFD3635937.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            1700..2386
                     /locus_tag="ACF3UE_002599"
     CDS             1700..2386
                     /locus_tag="ACF3UE_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3635938.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            2383..3888
                     /locus_tag="ACF3UE_002600"
     CDS             2383..3888
                     /locus_tag="ACF3UE_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFD3635939.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
BASE COUNT         1544 a          729 c          921 g         1237 t
ORIGIN      
        1 atgttgttct ttagtttgca atgtagccgt gttaagctat aatgtaagag attagggaga
       61 aatcccgtat gtaggaggag ttcatatgtc aaaacaacaa atcggcgttg tcggtatggc
      121 cgttatgggt aaaaatctag ccttgaacat agaaagccgc ggctattcag tggctttatt
      181 caatcgtaca ggggctaaaa caaccgctgt agtagaagaa cacccagata aaaatttcaa
      241 agcaacatat acaatcgaag aatttgtaga atctatcgag aaaccacgtc ggatcttgct
      301 aatggtcaaa gcaggaccgg caacagatgc aacaatccaa gagttacttc ctcaccttga
      361 taaaggcgat attttgattg acggaggaaa tacattcttt aaagatacga tgcgtcgtaa
      421 tgaagagtta gccaactctg gcatcaactt tatcggtaca ggcgtttccg gtggtgaaga
      481 aggagcttta aaaggacctt caatcatgcc tggtggacaa aaagaagcct atgcgctagt
      541 tgcaccaatc ttagagcaaa tttctgcaaa agcagaagac ggagcaccat gtgtcacata
      601 tattggccca aatggagccg gacattatgt gaaaatggta cacaacggta ttgagtatgg
      661 agatatgcaa ctgattgctg aatcttatga cttaatgaag aatattttaa acctttcagt
      721 agaagaaatg gctgatatct ttaaagaatg gaatcaaggc gaattagaca gctatttgat
      781 agaaatcact gctgacattc tgacacgtaa agacgatgaa ggaacaggta aaccagtagt
      841 agatgtgatc cttgatgcag ctgggaataa aggaacaggt aaatggacaa gccaaagcgc
      901 gcttgactta ggtgtgccac ttccattgat cactgaatct gtatttgccc gctatatttc
      961 tgcttataaa gaagaacgcg tacaagcaag caagattttg tctcgtacga acgattttga
     1021 gttcacggga gacaaaaaag aattggtcga aaaaatccga gaagcgttgt atttcagtaa
     1081 aatcatgagt tatgcccaag gatttgctca attacgtgtc gcttcaaaag aatttgattg
     1141 ggacttgcca tttggtgaaa tcgcaaaaat ctggcgcgct ggatgtatca tccgagctcg
     1201 attcttgcaa aaaattacgg atgcctatga caaaaatcct gagatcgaaa atttattgct
     1261 agatgattac ttcgttgaaa tcacgaaaaa atatcagcaa tcagtcagag acgtcgttgc
     1321 cttggctgtc caagctggcg tacctgtacc gactttctca tcagccatcg cttacttcga
     1381 ttcatacaga gcagaacgtc tgcctgcaaa tataatccaa gcccaacgcg attactttgg
     1441 cgcacatacc tatgaacgtg tcgacaaaga aggaatcttc cattactcat ggtaccatga
     1501 agaataatag tctttcggct gttaggaaat gagaaaataa aaagaggacg aaagagctga
     1561 agtcgattgt tatgagtaga cttcagctct tttttaaaat tgctatccat gataaaatga
     1621 ctatagattt ttaagcatat tatcggtata atgatagagt ttttaaaaag ccagtagaat
     1681 agaaaggata aaataataaa tgagcaatat tctaatcatt gaagatgaaa agaacttggc
     1741 acgatttgtc gagctagagt tgaagcatga agggtataac gcagaagtcc actacaacgg
     1801 ccgaactggt ttagatgcgg cattaaataa tgagtgggat gccatattgt tggatctgat
     1861 gctcccagaa ttgaacggtt tagaagtctg cagacgtgta cgccaagtca aaaatacacc
     1921 aatcattatg atgactgcaa gagattctgt gatcgatcgt gtatctggac ttgaccacgg
     1981 agcagatgac tacatcgtca aaccatttgc tatcgaagaa ttattagcac gtcttcgtgc
     2041 attgttgcgt cgaatcgata ttgaaggcga taaaaatgtg gctaaacaaa ctactattac
     2101 ttatcgcgat ttgactatcg aaaaagaaaa ccgtgtcgta cgtcgcggaa atgaagtaat
     2161 tgaactaaca aaaagagaat acgagttgct gcttacttta atggaaaacg tgaacgtggt
     2221 attagcacgt gacgttttac taaataaagt gtggggatac gaaacagaag ttgaaacaaa
     2281 cgtagtggac gtatatattc gttatcttcg caacaaaatt gacgttcccg gggaggaaag
     2341 ctatatccaa actgtacgcg gaacaggtta tgtgatgcgc tcgtgataaa gccgaaaaaa
     2401 tcggaaaaaa gagaactgaa agggccctcc ttgacaatca agtgggcctt tgcgagttct
     2461 ttcttcatat tcgttgtgtt tacaattttc gctgtcatta cctataaatc atctatcaat
     2521 ctgattgtgg caaaagaaag aaacaatgta gagcgtacga tttcagaagt agcttctcgt
     2581 ttggctaact cggatgaaga actgacatta gtaaatacgt atcgtaatct gacgaaagcg
     2641 acaaatgacg gagatgaggt cgtagatcat acttcactgg tcgaaggaaa cttaatgaag
     2701 atcgattcct ttatagctga gctagggcag ccatcaatgg atctttatgt ttatgatttg
     2761 gacgagaact tgatttttaa aacccatgaa aacagtcgaa acctgattca gactacacgt
     2821 aaagttccaa cgatcgttac actagaagga aaaactggct ttttatctat ccagcctata
     2881 tattctaaag gtacaagaga aaagatcggc tatgcgcaaa gcttctatga attatcttct
     2941 ttctatgata ttcgaaataa gctattattg actcttattg ttttagaagt tgtttctttg
     3001 atcttaagta gtattttagg tttcttttta tcttcttatt tcttaaaacc actcaaggta
     3061 ctcagagata caatggatac tatacgtaaa gatccgcaat cagatatcca catgcctgaa
     3121 atcgacacaa atgatgaatt ggcagattta gctgaaatat tcaatgagat gcttgaccgt
     3181 atgcgtttgt atattgaaca acaagagcaa ttcgtggaag acgtatctca tgagttaagg
     3241 acacctgttg caattattga agggcatctt agtctgctaa atcgttgggg gaaagatgat
     3301 cctgagatat tagaagaatc attaagcgcc agcatgcaag aaattagccg tatgaaaagc
     3361 ttagttcaag agatgctaga cttatcaaga gcagaacaag tagatgttca ttatgcgaat
     3421 gaaacaacta aaggaaaaga agtcacctat caagtttata ataatttcaa gatattatat
     3481 ccagactatg tgatcacttt agatgatgat ttgacaaaag aagtgaccct gcaaatttat
     3541 cgtaatcact ttgaacaatt aatcattatc atattggata acgcagtaaa gtattcaact
     3601 acacgaaaag aagtccatat ctctatttct tccactctga atgaatttga gatcgcgatt
     3661 caggactttg gcgaaggaat acccaaagaa gaccttaata agatcttcaa tcgtttttat
     3721 cgagtggata aagcaagagc tagaacgaag ggtggaaatg gtctggggtt gtctatcgct
     3781 aaacaactgg ttgaaaacta taaaggacgt atcttagcag aaagtgtagt agggcaaggg
     3841 acaattttta gaatctttat tcctatcgca aaggcagaag acaagtaaag catgtgcttt
     3901 acttgttttt ttatatatcc aacaaagaat aaggtacaaa atacaagcaa gttagaaatt
     3961 cagggatgtc attataaaaa aaactagcga acaattaaat agaataacat ccgttaatta
     4021 aacgtaagta gcttttagat gaacgaaaaa acaatgaaat gctgtaatat tcgtgtttaa
     4081 aaataataaa taaaaatagg gaattttcta ttgcaatttt ataaagagat tgctatatta
     4141 ttatttgttc taaatgattc ctttaaggtg tcactaaaaa ttataaaaaa tagggttgac
     4201 gcacttttga tgtcatgtta taataacgaa gtcgtttgga tgaggtagct aataaagctt
     4261 gattttatcg aaaaaaactt cgaaaaagtt gttgacaaat aacaataaag atgatatgat
     4321 aatcaagtcg ctgctaatga gtgacaaaga cgtttagaaa aaataaacaa agaagttgtt
     4381 gacattctct tctgaatctg ataagattaa agagttgttg aaacaaaaag a
//
LOCUS       DAXLPC010000131         4416 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.134, whole genome shotgun sequence.
ACCESSION   DAXLPC010000131 DAXLPC010000000
VERSION     DAXLPC010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.134"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            59..913
                     /locus_tag="ACF3UE_002601"
     CDS             59..913
                     /locus_tag="ACF3UE_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFD3635940.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="ACF3UE_002602"
     CDS             1010..3259
                     /locus_tag="ACF3UE_002602"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFD3635941.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3262..>4416
                     /locus_tag="ACF3UE_002603"
     CDS             3262..>4416
                     /locus_tag="ACF3UE_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3635942.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1556 a          625 c          806 g         1429 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga tatcggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatc gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga tttgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actaga
//
LOCUS       DAXLPC010000132         4372 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.135, whole genome shotgun sequence.
ACCESSION   DAXLPC010000132 DAXLPC010000000
VERSION     DAXLPC010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.135"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(83..1051)
                     /locus_tag="ACF3UE_002604"
     CDS             complement(83..1051)
                     /locus_tag="ACF3UE_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFD3635943.1"
                     /translation="MSKKRTIVNEWEKLTALSNRRLNVQTLVQTIKLNWSIDRITIVG
                     KLNQNIFYHTQHDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQHDENIAYIEISKW
                     QEGKGRIDFNPNKISRFLADSMKNFIHDLFLEPHFSRADVACDLIDVPDEFITQYRII
                     DPVSFKLIYGRSGKLETVYWGSRASERQIRLYNKKIEQEMKRKVVPSEINTWWRLEMQ
                     LRRGKATEWYAMVKESLDSFVSPHFLPTDIKPTDKVMIDGLLANHSNWAILSRNSKYK
                     YRNLLKRESQNDELTNHLRETFEESADDLKKELDTWLQGLDVTEEE"
     gene            complement(1496..2902)
                     /locus_tag="ACF3UE_002605"
     CDS             complement(1496..2902)
                     /locus_tag="ACF3UE_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HFD3635944.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDRQKTNDWHKHIDFTKSDEN
                     IYLEQTNLADKYEELFGEVVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     ILDDFQTNRADGSSTGISKQQAEQNRVIANKILVQYYKEFQERNPNLAVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALVQQGIHADKDNGRVLFNNFRNQEVDSIE
                     RLMNDYGWKRDIVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYIYRQREE
                     NERDKALMASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSENEIEW"
     gene            complement(3124..3486)
                     /locus_tag="ACF3UE_002606"
     CDS             complement(3124..3486)
                     /locus_tag="ACF3UE_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635945.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKTVDNEWLADEKSAPSERDYPDESDDLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(3490..3798)
                     /locus_tag="ACF3UE_002607"
     CDS             complement(3490..3798)
                     /locus_tag="ACF3UE_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635946.1"
                     /translation="MDKIDLREETVDRIELMYERLADYLNLPDEDNYSEMLERIMDVL
                     NSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQISVINSKEKEM
                     "
     gene            complement(3807..4226)
                     /locus_tag="ACF3UE_002608"
     CDS             complement(3807..4226)
                     /locus_tag="ACF3UE_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635947.1"
                     /translation="MTDLPEKMTIKNLADELGISKNTVRNQLVNAGYDLARYKDNGVI
                     MLDKELIGVVRSIYRSKGGQLTGDLPVNDAGNDFPLEKENEFLREQLAEKDRHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
BASE COUNT         1241 a          979 c          604 g         1548 t
ORIGIN      
        1 aaaaaaacaa cgacaacgtt atcacctgtt aaattcacca accaattttt cttaccaaaa
       61 tgcttttgtt tttctgccat tactattcct cctctgtcac atcaagtccc tgtaaccaag
      121 tatccaattc tttttttaaa tcatctgctg attcttcaaa tgtttctcgt aaatgattcg
      181 tcaactcatc attttgactt tctcgcttta ataaatttcg atatttatat ttcgagtttc
      241 ttgacaaaat cgcccaatta gaatgattag ctaacaatcc atcaatcata actttatccg
      301 taggttttat atcagttggt aaaaaatgtg gactcacaaa gctatccaaa ctttctttca
      361 ccatagcata ccattccgta gctttaccac gtcttaactg catttctaac cgccaccaag
      421 tattaatttc tgaaggcacc acctttcttt tcatttcttg ctctattttt ttattgtaca
      481 aacgaatttg ccgctcgctt gcccgactac cccaatacac cgtttccagt tttcctgagc
      541 gtccataaat taatttaaat gaaactggat caataattcg atattgcgtg ataaactcat
      601 caggcacatc aataagatcg caggcaacat ccgctcgtga aaaatggggc tctaaaaata
      661 aatcatgaat aaaatttttc atggaatccg ctaaaaatcg actgatttta ttaggattaa
      721 aatcaatccg cccttttcct tcttgccatt tagaaatttc aatataggca atattttcgt
      781 catgttggtc taatagctgc caaccattat ttccaaccgc ttttaaatag ccattgcctt
      841 catttacccg cataagctgt tcaaaatcta atattaatac atcatgttga gtatgataaa
      901 aaatattttg attcaacttt ccaacaatgg taattcggtc aatcgaccaa tttaatttta
      961 tagtttgtac caaagtttga acatttaacc gcctgttaga cagggctgtt aatttttccc
     1021 actcattcac gattgttctt tttttactca tattcagttc ctcctcaaag aaaaaagaga
     1081 tttttggaaa gaatttccag agttcacgta actctaaaaa ttcataacca tcaatctcta
     1141 gtcttgaaga aacctaaaaa tattcgtata atgaatttga gttacggaac tagtgtggtt
     1201 agtttccgta aaggtcgaga acgttggtag cgttgctcga cttatttttt tgctcttttt
     1261 ccagttcatt tgtttgctaa ctcaataata gcacttctct ttagctatgc aaataccaaa
     1321 aaaataaaac cgcacccttt gaaaagggcg cccccaaact tcgctaacgc taagttggcc
     1381 aaaaaatgga cttgccattt tttagcaaat gtcagcttca ggggctagtg gtttagccgt
     1441 caactcctta tcctcggcac aaaccgcctc cggtaccgtt gactgcacat cgtggctacc
     1501 actcaatctc attctcagaa cgctctaatt tatgctgtga gacgttttga cgataaaata
     1561 aggttttctc ctgctctaat acttctaatt cctcagaaag ccccatatcc ttttctgcaa
     1621 gaccaaaacg gatagacaaa cgagtgatcg atttttgaaa tgcgtttttt aatcgctcta
     1681 aacgctggcg taaagagcga ttttcttctt tcagcttttt attttccact tgtaaatctg
     1741 ctaattgttt tctaccagac aaatgacgct cttcttccaa tgtagctaca tactcattta
     1801 attctgtatt ttgctcaagc atctgtaaat attgctcact catgttatca gcatttctct
     1861 tggcatttgt tgctctcgta gctcgttgat acaaatcaac aaaatcattc ccagataaat
     1921 gatacgaacc atcaggaagc ctcttgaaac tttctaaagg aaccatatct ttttggaaaa
     1981 tgaccgccat ctcttttttt acattcagca tatttttctt ctcttcttca atcttcgctc
     2041 tctcagaagc catcagagcc ttatcacgct cgttttcttc tctttgccta taaatatacc
     2101 tcaactcatc agaaacgctc tcacgctctt ttacagccgt ttggcgcaat tcagaaattt
     2161 cactcatgat ttctttgtat tcgtgaatat ctttaatttt gttggtaccg acaatatccc
     2221 ttttccaacc gtaatcattc attaatcgtt ctatagagtc aacttcttga tttctaaaat
     2281 tattgaaaag cactcgacca ttatctttat cagcgtgtat cccttgttga accagtgctt
     2341 tattaaagct cggctgcttt tgaacacccc gtttataacc ttcagcaacc ggcacaatat
     2401 tcaagtgcag gtgcggactt atttcgtcat tatgaataac agcattataa acagccaaat
     2461 tagggtttct ctcttgaaac tccttgtaat actgaaccaa aattttattg gcaatcactc
     2521 gattttgttc agcttgttgt ttcgatatgc cagtagaaga accatctgct cgatttgtct
     2581 ggaaatcatc taaaatgcct atttgcacaa taaattctcg ttgaggttcc aactttttat
     2641 ccttgcgcac tttcgctaaa tagtcctcga tttttctatc ggctcttttt tgtttcgcat
     2701 tatatttttc taccacttcg ccaaacaatt cctcatattt atctgctaga ttcgtctgct
     2761 ctaaataaat attttcatcc gatttcgtga agtcaatgtg cttatgccaa tcattggttt
     2821 tctggcgatc agttaactca cgattattat gagaaatact tgtattcttc gttccttttt
     2881 taaatgaaat actaaacccc aagttaaaac cctccttcgc gctgtcgcta ataaaaagat
     2941 tgtaaacctt tctgttactc tttgtcaaag agtaacattt tcctaattgt gacatggatg
     3001 tcacaattcc aaacgctctc cgagggtttt cgctgtcaca agtgacaacg aaaaaaggag
     3061 ccgaaagcgt atcacgctat caactccttt tatgctttat tttgcttcac gcaaaataat
     3121 cgcttatcgt aaattcacgt cattaaatat tgacgtaaat ttactctcac tcatctgact
     3181 tttcttattc ggtatcactc cgaataagtc gtcagattca tcgggataat ctcgttcgct
     3241 tggcgctgat ttttcatcag caagccactc attatccact gttttttcgt gttgctgatc
     3301 gtcagaaatt gacgataacc accgctcaaa atcagcaaaa gtttcaaacc caaaacgctt
     3361 gcgaagagcc ttgcccattg cagcattttc tttctcaatc aagcgttttt tctgttggcg
     3421 aagtttcgct tgttcttttt ttaatttttc ttcttgcgct ttaatatctg ctaaagtcat
     3481 tcccataaac tacatctcct tttctttgga attaataacg gaaatttggt ttaactgcat
     3541 aacatgactc attaatttca accaaaattc tttttctgat tcatcagttg tttgcgctaa
     3601 atgcttatga acaaattcat tagtcaaaac tgaagatttt gctagatcag cattgataac
     3661 cgagttgaga acatccataa ttcgttcaag catttcacta taattatctt catccggcaa
     3721 attcaaataa tcagctaacc gttcatacat caattcaatt ctatcgactg tttcttctct
     3781 caaatcaatt ttatccatgt cacacctcac ttccagaatt gccaccattt tcgatttttt
     3841 aattcttgat tttctagtaa caactgatcg tttttttgtt gctgaagcaa agtcaatttt
     3901 tgttggtcac gaatcatttc cgttaattca gaaatatgcc tatctttttc cgctaattgt
     3961 tcacgcaaaa attcattttc tttttctaac gggaaatcat tgcctgcatc attgaccggt
     4021 aaatcaccag tcaattgacc accttttgac cgataaattg accgcacaac accaatcaat
     4081 tccttgtcta acatgataac cccattatct ttataccgag caaggtcata acctgcattg
     4141 accagttgat tgcgcactgt atttttagat atacccaact catcagcaag gttttttatg
     4201 gtcatttttt ctggcaaatc agtcattatc ttctccgtta ctttcagcta ccccataaac
     4261 atatttaaca gcatgcttag ggataatgat tggggaatca attttattat ttttcaaaat
     4321 caactcatac tgcgttacat caagtaactt accggacatt tttttgctat cc
//
LOCUS       DAXLPC010000133         4127 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.136, whole genome shotgun sequence.
ACCESSION   DAXLPC010000133 DAXLPC010000000
VERSION     DAXLPC010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.136"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            92..418
                     /locus_tag="ACF3UE_002609"
     CDS             92..418
                     /locus_tag="ACF3UE_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFD3635948.1"
                     /translation="MKKNSKEFRNEYDRFVLKFLIDNYYISRIDLSKAIGLAPSYVRE
                     FYNGSRSFGNEALEKLESTIFNLYKPLLENHSFELNQVQEMIESIDSEEELELFRLKG
                     ANVLDI"
     gene            803..2296
                     /locus_tag="ACF3UE_002610"
     CDS             803..2296
                     /locus_tag="ACF3UE_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFD3635949.1"
                     /translation="MTASLDVVYSTILQNGIRKFKYKNSRLKPVSFSEQTGKGAIFAY
                     RSKEHMVEGIGLVITSEEGIIENNNAFSHWTPNVFRYGTYTDEGRMFTKGHSEDNLRQ
                     INTFFVDFDTLDPNFDYGEILLASHELGFMPTMVLRTPHGYQAFYVLDQPAFVTKKSN
                     FKVINVAKMISNNLRKTLAKDFPVDVNANHFGITRMPNEDNTLFFEPQYRYSFADWIN
                     WSMRVDADKAVTYRNVFELPSNQDFRQVDEPWFRLLMRSEKIKGEKGRYGRNNVIFTL
                     SLAYFSSGYEIEECELAMLEFNDRLAYPLTDRELTRIIRSAYSGKYQAAHREKIILLC
                     QEWIDENLSEEQLFNKKKGWWKFKKERKVRKYSHSHEWAQDLLAYLNQQSYTYKPYIV
                     STKKELREELKIPERSLDKVLKQLKNENKIYYRVRSGRNGGITLASVHGLMRSIIRVK
                     KEVQEAYFSAISEVFGLARTFIYSTLEQLIEAPKKAEQMELFEVDTG"
     gene            2454..2738
                     /locus_tag="ACF3UE_002611"
     CDS             2454..2738
                     /locus_tag="ACF3UE_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFD3635950.1"
                     /translation="MGVNTFVYPYPVSVFIIQRLGMTVEEFCELHGYRQSTVATWAYR
                     NRPVKVLPCDFLYCLSLASGLSMDKVYQDLLLLEEKFLQSLDPKKEKKSI"
     gene            2774..2899
                     /locus_tag="ACF3UE_002612"
     CDS             2774..2899
                     /locus_tag="ACF3UE_002612"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635951.1"
                     /translation="MFRVEIVEKKTIEKLEKAVNNILISKGDKVQTIEYAAVKKI"
     gene            complement(3126..3806)
                     /locus_tag="ACF3UE_002613"
     CDS             complement(3126..3806)
                     /locus_tag="ACF3UE_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFD3635952.1"
                     /translation="MNHFKGKQFQKDVIIVAVGYYLRYNLSYRDVQEILYNRGINVSH
                     TTVYRWVQEYGKLLYNIWKRKNKQSIYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPRVLVTDKAPSIASAFKKLQAHGFYQRTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYRSLRTASTTIKGMEAIRGLYKKNRKEGTLFGFSVCTEM
                     KILLGIPA"
     gene            3992..>4127
                     /locus_tag="ACF3UE_002614"
     CDS             3992..>4127
                     /locus_tag="ACF3UE_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
                     /protein_id="HFD3635953.1"
                     /translation="MSTVILAEKPSQALAYASALKQSTKKDGYFEIKDPLFTDETFIT
                     F"
BASE COUNT         1320 a          671 c          861 g         1275 t
ORIGIN      
        1 atattaaaaa aaggattgta tataaatttt tttgatggta atattataaa cgaggatgtt
       61 gctataatta acaacgaaga ggtaagattt catgaaaaaa aactctaaag agtttagaaa
      121 cgaatatgac agattcgttc ttaagttttt gattgataat tattatataa gccgaattga
      181 tctatctaaa gctattggat tagctcctag ttatgtgcga gaattttata atggatctcg
      241 tagctttgga aatgaggcat tagaaaaact agaatcaaca atttttaact tatataaacc
      301 tttgctagag aatcattcat ttgaattaaa tcaagtacag gaaatgatag aatcaattga
      361 ttctgaagag gaacttgagt tgttcagact taagggagct aacgtattag acatttagat
      421 aatttctact tgatttggta aattatattt acaactttca acagattcgg taagataaaa
      481 aaaatatata aaaaagagac ggataaacaa gtgaattgga cctcactcat ttatctgaat
      541 cacataaagc aactatgtgt tctcgctcgt ctcaaggaaa ttatgtaagt ggtagccaac
      601 cacttatgtg atttgaataa atctgttcgg actaccaatc cgaacctgta ggtttatttt
      661 accattttta gacgggcaac tcaatagata aacgcttatt tgtcatgctt tctttagatt
      721 gttttgatat ttctagcgat tgagagaaca cagatcgaac gattatttgt gttctctttt
      781 tgtttagaaa ggataagtag gcatgacagc ttctttagac gtcgtttatt caacgatctt
      841 acaaaatggt atccgtaaat ttaaatataa aaatagccgc cttaaaccgg tctcttttag
      901 cgaacagacg gggaaagggg ctatttttgc gtaccgttca aaagagcata tggttgaggg
      961 aataggctta gtgatcacgt ctgaagaggg cattatcgag aataacaatg cgtttagtca
     1021 ctggacccca aacgtcttcc gctatggcac gtatactgat gaaggcagaa tgtttacaaa
     1081 agggcattct gaggacaatt tacggcaaat caacactttc tttgttgatt ttgacacctt
     1141 agacccaaat tttgattatg gagagatttt gttggcaagc catgagctag gatttatgcc
     1201 aacaatggtt ttgcggactc cccatggtta ccaagcgttt tatgtactgg atcagccagc
     1261 ttttgtgaca aagaaatcca attttaaagt gatcaatgtg gccaaaatga tttctaacaa
     1321 cttgcgaaag acattagcca aagattttcc tgtagacgtc aatgccaatc attttggaat
     1381 cactcgtatg ccaaatgaag acaatacctt attctttgag ccccaatatc gttatagctt
     1441 tgcggactgg atcaactggt caatgcgtgt cgatgcggat aaagcagtaa cctacagaaa
     1501 cgtttttgaa ttaccgtcaa atcaggattt tcgccaagtg gacgaaccct ggttccgtct
     1561 attgatgcgt agtgaaaaga ttaagggaga gaagggaaga tatggtcgaa ataacgtcat
     1621 atttaccctg tctttagcat acttttcttc cggatacgaa atcgaagagt gcgagttggc
     1681 catgttagag ttcaacgatc gattagccta tcctcttact gatcgggaac tgacacgaat
     1741 tatccgatcg gcttattcag gaaagtacca ggcagcgcac agagaaaaaa ttattctatt
     1801 atgccaggaa tggatcgatg aaaatttatc tgaagaacag ctgtttaata agaaaaaagg
     1861 ctggtggaaa ttcaaaaaag agcgtaaagt gcgcaagtat tcgcacagcc atgagtgggc
     1921 gcaagatctc ttagcttatt tgaaccaaca atcatacact tataaacctt atatcgtttc
     1981 aaccaagaaa gagttaagag aagagcttaa aattcctgaa cgctccttgg ataaagtatt
     2041 gaaacagctg aaaaatgaaa ataagatcta ctatcgtgtt cgttccggtc gcaatggggg
     2101 gataactttg gcgtcagtgc atggcttgat gcgatcgatc attcgagtga agaaggaagt
     2161 ccaagaggcg tattttagtg ctatttcaga ggtttttgga ttggcacgta catttatcta
     2221 ctcaacgctg gaacaactca tagaggcacc taaaaaggct gaacaaatgg aattgtttga
     2281 agtggatacc ggataaaaat aaaacccgca aattgccttt tacattatat ctttgatacg
     2341 ctctccgagt cagaggtttt acaggtctta gggaattccc ttgattgcaa tgtttggata
     2401 agtgaggtac tattatcgca tatgtgatta tatttcttag ggggttaccg tccatgggag
     2461 tgaatacttt tgtttatcct tatcccgtca gtgttttcat tatccagcgt ttaggtatga
     2521 ctgtggagga attttgtgag ttacatggtt ataggcaaag taccgtagca acttgggctt
     2581 atcggaatag gcctgtaaaa gtcttaccct gtgattttct gtattgtttg agcttggctt
     2641 ctggtttgtc aatggataag gtttatcagg atttattact gttggaggag aaatttttac
     2701 aaagtttgga tcctaaaaag gagaaaaaat cgatttaaag tttagtaagt ttgaaaggaa
     2761 gagggggata ataatgtttc gtgtagaaat tgttgaaaag aaaacgattg aaaaattgga
     2821 aaaagcagtg aataatattc ttattagtaa aggggataaa gtacagacta tagaatatgc
     2881 tgcagtaaaa aagatttaaa cgtctattat tctgctatga ttgtatataa ggcttgagga
     2941 tgttttgagt tgttaggaat ctaagggaag taaaaatatt tctataggag aacagaaaag
     3001 atggataatg atcattgtga gaatgtaaac aagttagaaa gtgcgggtaa aacttattat
     3061 attattggtg cggttctgtt gcaaagttcc aaaatgaaca atactagtct aacactagct
     3121 atagtttatg caggtattcc taataatatc ttcatttccg tgcagactga aaacccgaag
     3181 agagtgcctt cttttcggtt cttcttatat aatcctcgaa tggcttccat gcctttaatc
     3241 gtggttgagg ctgttcgtaa gcttcgataa aatttgtttc gtctcttgat gggacgatga
     3301 tcttgttcaa tgaggttatt tagatatttc accgtgcgat gttctgttcg ctggtaaaac
     3361 ccgtgtgcct gtaatttttt gaaggcactg gcaatagagg gagctttatc ggtcaccaga
     3421 acccttggtt catcgaactg tttaactaat ctcttgagaa aggcgtaagc tgcttgtgta
     3481 tctcgctttt tccgtaacca tatatccaga gtgagaccat ctgcatcaat ggcgcgataa
     3541 agataatgcc attttccttt gattttaata taggtctcgt ccattttcca cgaataaatg
     3601 gactgtttgt ttttcctctt ccaaatgttg taaagtagtt tcccatattc ctgtacccaa
     3661 cgatagacag tggtgtgaga cacgttaata ccacggttgt acagaatttc ttggacgtca
     3721 cgataactca ggttgtaccg aagatagtag cctacagcga caataatcac atctttctga
     3781 aattgtttgc ctttaaaatg gttcatcttc gttactcctc ctagttccta ttaaactcag
     3841 tttaccctat aatggatctg aggggaaact ttgcaacaga accagttgaa gaacaaactg
     3901 gaatcaatcg ccgaacgttt agaaggtatc gagcaagata taacgtgaca gtagatcaaa
     3961 gaaaaaacaa tgaaaagagg gatagttaat gatgagtacg gttattttag ctgaaaaacc
     4021 aagccaggca ttagcctacg caagtgcttt aaaacaaagc accaaaaaag acggttattt
     4081 tgagatcaaa gacccactat ttacagatga aacgtttatc acctttg
//
LOCUS       DAXLPC010000134         4029 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.137, whole genome shotgun sequence.
ACCESSION   DAXLPC010000134 DAXLPC010000000
VERSION     DAXLPC010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4029
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.137"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            179..775
                     /locus_tag="ACF3UE_002615"
     CDS             179..775
                     /locus_tag="ACF3UE_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFD3635954.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="ACF3UE_002616"
     CDS             899..2698
                     /locus_tag="ACF3UE_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFD3635955.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="ACF3UE_002617"
     CDS             complement(2976..3188)
                     /locus_tag="ACF3UE_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635956.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="ACF3UE_002618"
     CDS             3650..3799
                     /locus_tag="ACF3UE_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635957.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
BASE COUNT         1182 a          689 c          712 g         1446 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctacaatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtata
//
LOCUS       DAXLPC010000135         4001 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.138, whole genome shotgun sequence.
ACCESSION   DAXLPC010000135 DAXLPC010000000
VERSION     DAXLPC010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.138"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(325..2322)
                     /gene="tkt"
                     /locus_tag="ACF3UE_002619"
     CDS             complement(325..2322)
                     /gene="tkt"
                     /locus_tag="ACF3UE_002619"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFD3635958.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPIGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2424..2675)
                     /locus_tag="ACF3UE_002620"
     CDS             complement(2424..2675)
                     /locus_tag="ACF3UE_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFD3635959.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2822..3445
                     /gene="lexA"
                     /locus_tag="ACF3UE_002621"
     CDS             2822..3445
                     /gene="lexA"
                     /locus_tag="ACF3UE_002621"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFD3635960.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3624..3842
                     /locus_tag="ACF3UE_002622"
     CDS             3624..3842
                     /locus_tag="ACF3UE_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635961.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
BASE COUNT         1114 a          847 c          730 g         1310 t
ORIGIN      
        1 gagcaatcgc ttttttattg atcaccattt ttcttttagg tctatggtgt cgggcactgc
       61 gggtcttcag ctcttgcatt caaattcctc ctcaaaataa aaaaacttaa taaaaagttc
      121 tcttcttaaa acaaacttaa ttaattaaat tatactttta attctcaaga aacacaaact
      181 aatccgaaga attctttgtt ttgtcattta aatgtaacat agccgaaaac gaaaagtaat
      241 attgatttat tcttctaaca cataaagaac agctgtctcc aacttgcaga cagctgttct
      301 tatcagtcaa acaattgctt ggatctatga tagttgattg tacgtattca cgacattttc
      361 tactgtaaat ccaaattctt ctaaaatttt agtgccaggg gcagatgcac cgaaatgatc
      421 gattgtaatc gttgcgccct ctgttcctac gtagcgttcc caaccaaatg atgcagcagc
      481 ttcgatagcc acacgtttct tcactgattt aggaagtaca ctttctttat attcagaaga
      541 ttgtttttca aagaggtcaa agcttggcat agaaacaaca gaaacatctt tgcctttttc
      601 agccaattct ttttgagctt tcacagccaa atcaacttca gaacctgttg caatcaaaat
      661 accttctggt gtttctcctt gtgatggaga aagaacatac gcgccttttt tcaccatttc
      721 atctgctact tcttttgtag aaggcaatac tggaaggttt tgacgactca atacaaggat
      781 agtaggcgca tctgttgtct ccatcgctac tttccaagca gcacgtgttt catttccgtc
      841 tgccggacga atcacttgaa caccaggcat gcagcgaaca gatgctagtt gttcaatcgg
      901 ttcgtgcgtt ggtccgtctt ctccgacagc aaccgagtca tgtgttaaga cgtaaacaac
      961 aggagtatgt tggattgctg ctaaacgaac tgctggtctt agataatcga caaagacaaa
     1021 gaatgttcca ccgtagatac gagttccgcc atgaagttgg ataccattca tagccgaagc
     1081 cattgcaaat tcgcggacac cgaaccagat gttgcgtcct tcataatgtt caggagtgaa
     1141 atctttatct gcagccacca ttgtattatt ggaacctgac aagtccgctg aaccacccca
     1201 gaagcttggt atagctttcg ataattcttg gatgacttct ttacttgaaa cacggcttgc
     1261 ttgactgctt ccaacttcat aagttggcaa ttctgcatcc cagttttctg gtagtttgcc
     1321 atcaaaagca tcttcaaatt gttgtgctaa ttcaggataa gcttttttat aattggcaaa
     1381 catttcattc catgcatctt cagctttttg tccttcttct atcatcgttt gatggaagcg
     1441 ggcagctact tcttctggaa cagtgaaatc tggatactcc caaccataaa cttctttagc
     1501 catcttgatg ccatcttcac caataggagc accatgaaca gcagatgttc cttctttagg
     1561 agcaccatag ccgatgactg tttttacttc gatcaatgtt ggtttgtctg tttcagcttt
     1621 tgcttcttca atcgctttag agattgcttc taggtcattt ccgtctttca ctaagatatg
     1681 ttgccagcca tatgcttcat agcgagcacc aacgttttct gtgaaagctt ttgaagttgg
     1741 accgtctagt gaaatatcgt ttgaatcgta taaaacgatc aatttcccta gtttcatatg
     1801 acctgccatc gaacttgctt cttgagatac cccttccatc aagtctccgt caccgcatat
     1861 tgcatacgta tagtgatcca tcacattaaa gttttctttg ttatacgttg ctgcaaggtg
     1921 cgcttctgcc attgccatac cgacagccat tgcaatccct tgtcctaatg gccctgtagt
     1981 ggcttctaca ccatctgtgt gatgtacttc aggatgtcct ggtgttttag aatcccattg
     2041 acggaattgt ttcaaatcat cgattgtcac ttgatagcca gctaaatgaa gcaagctata
     2101 caacattgct gacccatgtc ctgccgaaag aacgaaacgg tcgcggtcag cccagttttt
     2161 tgatgtcgtt ggatttactt tcaggtgttt tgtccataac gcatatgcca taggtgctgc
     2221 gcccatcggc aatccaggat gtcctgagtt tgctttttgg actgcttcaa tacttaatgt
     2281 acgaattgtg ttaacgccaa gttggtcaat tttgtcaaac aaaataaccc ctcctattaa
     2341 tttaggtttt ttttaccttt atttcttaca ctttcattct ataagatgtc acacgaaaaa
     2401 gcaatctttt tcagtatttt ttactaaaag ttgtcatttc ggttgtgtaa gccttttttc
     2461 ttttggattt cttttaattt ttccggggtc acgtcattgc cctcaggatc gacgactttc
     2521 attccttcga tatgatgacg cataccggaa cgaaaagctt ccaaatactc tttgcgtaag
     2581 ttgatttgtt cttgttcttc ggcttttgag agaccatttt ccttcttttt acgtgcaagt
     2641 tcattgatcc tctctatttt ttcaggtgac agcatgctca gccctccttt tactctcctt
     2701 catattatat aaaaactgaa aaaaaaacaa ctagataaac taaataaaat acgaacattc
     2761 gtttgattta gcgcttttta tatggtacta tttatttatc aagtgaaaga aggtgtacct
     2821 tgtggcccga caaactgaat caagacaaat cgaagtctta cgatatatcc atgaacaagt
     2881 aacccaaaaa ggatacccgc cgactgtccg tgaaatcggg gaagctgttc agctttcttc
     2941 tacttctact gttcacggtc atcttgcacg gcttgaaaaa aaagggttta tccaaagaga
     3001 tccgacgaaa cctcgtgcaa tcgagttgac aaaacaaggt ttagaaaaga ttgggattcg
     3061 tccaacaact attccagtac ttggcgtcgt aacagctgga gaacccattt tagcagtaga
     3121 ggatgcttca gacttctttc caatccctcc taatctttct tccgaagaag gcagtctctt
     3181 tatgctgaca attcgtggag atagtatgat caatgctggg atcttggatg gtgacaacgt
     3241 gatcgttcgg aagcaagaaa ctgctcaaaa tggcgatatt gtcattgcaa tgactgccga
     3301 ggacgaagcg acttgcaaac gattctataa agaaaaaaac tttttccgtc tgcagcctga
     3361 aaacgacttg ctcgaaccaa tcatcttaga tcaagtatct atattaggac gagtagtagg
     3421 actttatcgt agtcatatct attaattgct actaataaaa gaaaactttt taaaaagagt
     3481 ttgagacgat ggtctcaaac tcttttttcg cccgggttct tcttctttca aatttttatc
     3541 acttccctct ttacaaaccg aacaaatatt cgtatactaa atatacgaac aattgttcgc
     3601 ataaattaac gaggtgagaa ttcatgaaat caatgagacg tcttggctta gtattaactg
     3661 ttttgttttt aggtattatt attggtaatt tcggcatacg tccagcttta cttgtgtttg
     3721 ttccgttatt tactttgtgg ttcatgttgt gggatgaaaa gaagtaccgt caatctgagc
     3781 ggcgcagaat tcatgaagat catttctatc atgagcccta ctacagatcc aggcaatcat
     3841 aataaggatt gactgctaat tattcaaaag acaagaagtt aaacttttac gggggtgtga
     3901 caaaaatcgg tcacatcctt ttttcgaata aacggtgttc taaagccagt ttttcggtat
     3961 taagtcaaat tgcggaaaaa gtgatttttt aaacttctac t
//
LOCUS       DAXLPC010000136         3928 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.139, whole genome shotgun sequence.
ACCESSION   DAXLPC010000136 DAXLPC010000000
VERSION     DAXLPC010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.139"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..787
                     /locus_tag="ACF3UE_002623"
     CDS             <1..787
                     /locus_tag="ACF3UE_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFD3635962.1"
                     /translation="FFESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESIS
                     ELRRKQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKE
                     YKATYEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVETI
                     DLKEACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKKH
                     EHEFVPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            798..2907
                     /gene="topB"
                     /locus_tag="ACF3UE_002624"
                     /pseudo
     CDS             798..2907
                     /gene="topB"
                     /locus_tag="ACF3UE_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            2923..3072
                     /locus_tag="ACF3UE_002625"
     CDS             2923..3072
                     /locus_tag="ACF3UE_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635963.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            3153..3749
                     /locus_tag="ACF3UE_002626"
     CDS             3153..3749
                     /locus_tag="ACF3UE_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFD3635964.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            3762..>3928
                     /locus_tag="ACF3UE_002627"
     CDS             3762..>3928
                     /locus_tag="ACF3UE_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFD3635965.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGS"
BASE COUNT         1434 a          682 c          849 g          963 t
ORIGIN      
        1 attctttgaa agtagtattg atctgttaag ttacgctgca ttgaatcggg agaaactaca
       61 agatgcctgg ttagtttcga tggacgggtt aaaacatcat gtaatcagtc attacgttga
      121 agagtcgatt tctgaattaa gacgaaaaca aacatttcct caatcgattg aaatatgtgt
      181 ggacaatgat cgtgcaggac atatttttta tgaaaaagaa cagatgaagg gaatcgttga
      241 tccttttacc aataagaaaa tccgttgtga gcgaggaatt ccaaatgatt ggcaagtacc
      301 taaagaatac aaagctactt atgaagcagt cgcaaaagaa atgagtgttg aacctgaagc
      361 aattatggcc atacacaaaa ctgaaactaa tttacagctg acaaatcaat tggtgtctgc
      421 tcatgatgtt caatctacgt ttggaaagat gttggcgaag ggcgaaccag tagaaacaat
      481 tgatttgaaa gaagcatgta ccacggtcgc gaaggaactg aaagtatgtg aacgcgcaga
      541 tggaacatac aactttgatc gtttttatag tagaaaagcc aacataaaag acgttaatgc
      601 aggaatcctt ctttcctata aagcagaaca atactacaaa ggctataaaa agcatgaaca
      661 tgaatttgta cctgaagtga aaaaggattg gaatgatcaa ttgaagcatg agatccagca
      721 acaagaaatc agaaagcaaa aacgtgcgat gttgtttcaa caaggcagac aacaagaaag
      781 ggagtgaagt cgtcactatg aaaaccgtca ttttagcaga aaaaccgtca caagcgaagg
      841 cttatgccga tagcttttct aaagctaccc gaaaagatgg gtattttgag atccaagatc
      901 gattgtttac aggagaaact gtgatcacgt atggttttgg tcatttagtc gagttagatt
      961 cgcccgatat gtacgatgaa aaatggaaac aatgggcatt agaacatttg cctattttcc
     1021 ccaatcaata ccactatcat gttcctaaag ataagaaaaa gcagtttagt gtcgtcaaac
     1081 gacagctgca gtcagctgat acgattgtga tcgcgactga tagcgatcgt gaaggggagc
     1141 tgattgcctg gtcaatcatt caacaagcag gcgccaatca aggaaaaacc tttaaaagac
     1201 tttggatcaa ctccttagaa aaagaagcca tttatcaggg attccaacag ttacgagacg
     1261 cagaagagac ctatccaaaa tttgaagaag tacaagcacg tcagatcgcc gattggttaa
     1321 ttgggatgaa cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa
     1381 gtttttcttt aggtagagtc caaaccccaa cactctatat gatttatcaa ttgcaggaaa
     1441 agattagaaa cttccaaaaa gaaccatatt ttgaaggaaa agcccaagta atcgctcaaa
     1501 atggcgcatt tgatgcgaag cttgatccaa atgaaaccca agcgacacaa gaagcatttg
     1561 aagcctattt aaaagaaaaa ggtgttcaat taggaaaaca gccaggtacg atccttcaag
     1621 tcgaaacaga gaaaaaaagt gcggctagcc cacgtctttt ttctttatcg agccttcagt
     1681 ctaaaatgaa tcaactcatg aaagctagtg ccaaagatac tttggaagcc atgcaagggt
     1741 tgtatgaagg aaaatatcta agctatccgc gaacggatac cccttatatt acggaagggg
     1801 aatatgcgta tctgttggat cacttagacg aatacaagca ttttttaaaa gccgaagcga
     1861 ttccgactcc tattcataca ccgaatagtc ggtatgtgaa taataagaaa gtccaggaac
     1921 attacgcgat cattcctaca aaaacggtta tgacagcagc ggcttttgaa caactaagtc
     1981 cactgcagca ggctatttat gaacaagtgt taaaaacaac ggtggccatg tttgcggaaa
     2041 agtataccta tgaagaaaca acgatcttga cgcaagttca gcagcttcag ttaaaggcaa
     2101 tcgaaaaggt gccgctagat ctaggttgga agaagttatt tggaaaagag agcgacggaa
     2161 aagagaagga agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtgg
     2221 atctacaagt tcttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga
     2281 tcactgcaat gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga
     2341 aagaagtgga aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac
     2401 aaaaggaata tatcaaggta gagaaaaata agctcgtggt gacgaataaa gggattttgc
     2461 tttgccaagc cgtggaaaaa gagccgctgc ttacgagcgc cgaaatgacc gccaaatggg
     2521 aaagctactt gttaaagatc ggtgaacgaa aaggaacaca aaccactttt ctagccaata
     2581 tccaaaaatt tgtctctcac ttattggaag tcgtaccagg gcaaatccaa tccactgatt
     2641 ttggatcgac gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt
     2701 taggaatttg tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt
     2761 gtacgtctga agcctgtgat tttaaaaggt cagaagggtt catttgaagc aacgattgtt
     2821 ttaaaagaag acttcactac aggctttgaa ttttctgaaa agaaaaaaac gaacttcaag
     2881 aaaagaacac gccgcactgc aaaataatgg agggttaatc ttatgcgtaa taccacacac
     2941 aaacaacaag aaatcgaaaa tcaaaaagcc aaaattcgtt cagaacagga aaaaatgcgt
     3001 gccagcaaac gaagactgca gcaattgaag aaccagcaga ggattcaaaa agaaatcgaa
     3061 ttagatcgat aaaatcttcc taactattgt atacgtataa acttatgtta tactgttttt
     3121 ataagtttat acgtatacaa aggagggaga aaatgacaaa agcaatggta tacaagctgc
     3181 tagaagaatt taatggaact ttggctttga aggatgccaa aaaagcgggc atttctcctg
     3241 taacgatcaa acgtatggta gatcgagggg agctggatcg agagtatcca ggttttttca
     3301 ccttacctgg tcaatttcct gatgaattgt ttatggcgca aaaaaaatat gaacgcggca
     3361 ttatttcaca tattaccgcg ttagatttgt atgatttaac agatatgatc cctagacaga
     3421 tcgatctgac tgtaccttac ggttatcacg tttctgaaaa aggattgaag gaattcgcag
     3481 ttgagctaca ctatacaaaa gcggaatggt atgaattagg taagattgaa ataaaaagtc
     3541 gctatgggaa tcctattata gcttatgatc cagaaagaac tttatgtgac atttggaatc
     3601 cctggtatac cgttgaggat gaaatcaaag taaaagcaat caaaaactat atggagtcgg
     3661 acagaaaaaa tcttagaaaa ttgaatgagt atcgacgaat tttaccaaca gacaaaacga
     3721 tgcgttctta tattatggct ttaaattaaa ggagaagata catgacacct acgcagttaa
     3781 aagcaaaagt gaagaatatt tctagagaaa aagaagttga tccgcagctt gttttaagac
     3841 attttatgat ggaaaaattc ttggaaaaaa tctcagagtc tccttatcgt gaaaattttg
     3901 tgttaaaagg cggcttcttg attggctc
//
LOCUS       DAXLPC010000137         3926 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.140, whole genome shotgun sequence.
ACCESSION   DAXLPC010000137 DAXLPC010000000
VERSION     DAXLPC010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.140"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(112..387)
                     /gene="prgO"
                     /locus_tag="ACF3UE_002628"
     CDS             complement(112..387)
                     /gene="prgO"
                     /locus_tag="ACF3UE_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="HFD3635966.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(359..1312)
                     /locus_tag="ACF3UE_002629"
     CDS             complement(359..1312)
                     /locus_tag="ACF3UE_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3635967.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            1924..3417
                     /locus_tag="ACF3UE_002630"
     CDS             1924..3417
                     /locus_tag="ACF3UE_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFD3635968.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            3552..3848
                     /locus_tag="ACF3UE_002631"
     CDS             3552..3848
                     /locus_tag="ACF3UE_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFD3635969.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
BASE COUNT         1307 a          646 c          703 g         1270 t
ORIGIN      
        1 tgttgtatac ccccaaacaa tacacatatt ttgaaggatt aggattaata aagctaaaaa
       61 tatagtaagt atactaaata tatttactat atctagtata cttactatat tttaatcttt
      121 tgatcgtcta ttatatataa tccgttcctc gtcgtttaaa gtatcaacat aggcgtccat
      181 tgcaagtttg actatttcat acataggaat atcttttgca taactaagat cccgaatggt
      241 ttttagtacg ggaggatcta cttgaactgg ttttctttct ttcgcagtgt actttcgttc
      301 ccctaactcg acattaatat catctttaat tgaaatatct tcagcaccaa ttttcttctt
      361 atctttgttc gttggtaata atgccattta gtttaatctc ctttccaaga ggtaggatat
      421 gattggccat tgagtcagca tatttaggtg tataatcaaa tccttcaata tcaccatgtt
      481 gttcatagta ttcaattctt tcttctaatt ctgtaaagat gtctgcaaaa atagcccacc
      541 atcttcgatc tacataatca tttaattgga taccattctc accatacatt tctaaccgat
      601 ccgagccttt aacaatgctt ttaaaaatgt ttgattcacc atacttatca attgtttttt
      661 gatagtttgc gtgttgagag gaacgtcgca ctgagaaaag aacaggcaaa attccaatga
      721 tttgaagatg agactcttca aaattcgtga caatcggaac taaaacttta ttaataaaat
      781 cttctgttcc ttccattgcg taccgtttta attcttgcat tgcaataata taatctgcag
      841 cagttaagaa tgcacgaacc acattatctg ttgatggtgg gcagtcgata aagatataat
      901 cgaaattttt tctcaattct tctaaaggtt taatgaaggc caatgatctc ttacgacgat
      961 caggatattt ttcggacaag tattcattaa gttcttcaga tccaggagag ccagccataa
     1021 tatataaatg tggacttact tgagtaatac ctgaaaccca gtcccctttt ttgattgctg
     1081 cagacatgga tcgatcaaag ctagtaattt gatacgttga tccaatgttg gaagtagtat
     1141 ttctttgttg gtcataatca attagcaaca cgtctttttc aaaaagttga ctagaaacaa
     1201 tcgctaataa atcattgtct gtagtcttac caatgccgcc ttttctacct gtaagcatta
     1261 caacttttcc tagtttatct gatgttttaa atgcagtccg taagttttcc atagttccct
     1321 ccaatttcct atactaaata tatttagtat acttcatata cttaatatat tcgatatatc
     1381 taatatactc caaattgata agaattcaga ctttataagg aatatagtgg atatactaaa
     1441 tatatttgct atattcagta tatcagatat attcaaaatg tcaaaatata tttgtgcgtt
     1501 ttgcgttgac aatttagagt gaaaagaggt aaacttaatt ctatagaaac cacagataat
     1561 tcactattta caaagtagca aaagcagtgg tactctttaa acagaaaaat tacataaaaa
     1621 aaagagacgg aaataattga ttttagcaga atcaattatt tctgaatcac atggttagga
     1681 catgtgttca cgctcgtctc aagaatatgt aagtagctac caactactta tattaaaagt
     1741 tgatcggata ccttttccga ttgcctttat tctaccaaaa aaaggcgagc aactcaacag
     1801 aagaacgttt atttagtgta cttaaattaa atattcttaa acactgaaga gagaacacat
     1861 actatggctg agattaaagc taaactgtgt tctctttttg tttgagaaag gacgttacaa
     1921 tcgatgttga gcgaaattta ttcagctatt cttaaaaacg gcttacgtac atacaaatat
     1981 cgaaacagca ccatgaaacc tgcaggtcat attgattcca gtaggagtgg tgctatcttt
     2041 gcgtaccgta gcaagcaatt aatgaatgtt gggcgtggta tggtcattac ttcggaagaa
     2101 gctattttag agaacgaaaa gaaactaacg cattggacac ctaataccta tcgctttggt
     2161 acttatgcgg atgattatcg aacagtggtt aaaggtcatt ctgagaaaaa cttaagtcaa
     2221 atcaacacat ttgtagttga tatcgattca aaagagaacc atcaaggcga aattatttta
     2281 gcctgtttag atcaagtggg ctacatgcca acgctaattt tagaatcaga tcatggttat
     2341 caagtttatt ttgtactaaa gacaccaggc tatgtcacaa agaaaagcaa tttcaaggtg
     2401 atcgatgtag caaaaaaaat ttcaaaaaca attcgtctac agttggctga aaaattgtcc
     2461 ggagtggatc taggatgtaa ccacttcgga attgctcgat tcccacaaga aaataatatt
     2521 gtttttaaag aaatgaacta tcagtattct tttgctgact ggattcaatg gtcgatgaag
     2581 cttgaatcag atcaaaaaac aaaagaagat cgagaacgaa aactaattgt ctttcctgag
     2641 aaaaaagaaa ttcgtcaagt agatgaaccg tggttcgata tgttacttca taaagcaaac
     2701 atcgtcggcg gagaaggacg tcttggtcga aataatgtga ttttcacgct ttctttagct
     2761 tattactctt caggttatgc attggatact tgcgaataca atatgttcac attcaacgaa
     2821 cggttacagg aaccgctatc tgaagcagaa ttagtaaaga ttgtacgtag tgcttattct
     2881 ggtaattatc aagcagcaag cagagaattc attattgaat tgtgccagca atgggtttca
     2941 ccaaccttaa aaaataatga tctgttcatt caacgacgtg gctggtggaa atttaaaaag
     3001 ccacgagatc aaagaaaata tagtcataaa aatgaatgga aagaagatct attggcttat
     3061 ctaagcgaaa aaagtcttgc tagtgagcct tatttgaacc tgtcaaaaaa agaattggct
     3121 tcacaactaa cgatgcccaa gcgaacactt gataagatct taaatgagtt acgagaggag
     3181 aataaagtct tctacaaggt aacacgagga agaaatggcg gaatgatcat tgcttcagtc
     3241 aaaacgttgt tcgcgagggt tattcaacta agtaaagaaa agagactaga ttattcaaca
     3301 aggatcacag aggtatttgg actcaacgag agcttagtag aagagacatt tagacaatta
     3361 tcaaccccct tgaaccctct taaagaagtg aatctttttg aagtagatac aggttgaaaa
     3421 ataaaaggtg caaattgcct tatacaatat atctatgata cttctgtagg tgttgctccc
     3481 tttgcctagc tacgtgtagg tggtatactt ataactgcgt atgcagtctt atgtatcatg
     3541 gaggaagttg tatgtcgtta aaaaattatg tctattcaca tcctgttaat gtgtttatca
     3601 ttggtcgttt gggattatct gtggaagtgt tctgtgagct ttatggtttt aagcagggga
     3661 ctttgtcttc ttgggttacc agggaaaaaa cagttgcttc tttgccgatt gagtttcttc
     3721 atgggttgtc cttagcttct ggggagacta tggatcaggt atatgattgt ttgtgtgtgt
     3781 tagagcagga gtatattgag tataaaatag ctaacgagtt aagaaaaagg aagaagtata
     3841 tccagtagta gtttttattt actcttaatt gtcaaattaa gttagacaaa tcatcaatac
     3901 ttacgtaact caaaaatact tccaaa
//
LOCUS       DAXLPC010000138         3654 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.143, whole genome shotgun sequence.
ACCESSION   DAXLPC010000138 DAXLPC010000000
VERSION     DAXLPC010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.143"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..776
                     /locus_tag="ACF3UE_002632"
     CDS             <1..776
                     /locus_tag="ACF3UE_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635970.1"
                     /translation="THEIILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERPLK
                     NAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYG
                     CEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSF
                     KIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGR
                     SVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            883..936
                     /locus_tag="ACF3UE_002633"
                     /pseudo
     CDS             883..936
                     /locus_tag="ACF3UE_002633"
                     /inference="COORDINATES: protein motif:HMM:NF019662.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            970..2346
                     /gene="tet(L)"
                     /locus_tag="ACF3UE_002634"
     CDS             970..2346
                     /gene="tet(L)"
                     /locus_tag="ACF3UE_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HFD3635971.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            2910..>3654
                     /gene="mobV"
                     /locus_tag="ACF3UE_002635"
     CDS             2910..>3654
                     /gene="mobV"
                     /locus_tag="ACF3UE_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="HFD3635972.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGL"
BASE COUNT         1163 a          555 c          754 g         1182 t
ORIGIN      
        1 cgacacatga aattatactt tctttcttag ggaaagtaca aatggaagtg attagtgcac
       61 tgttgcaaga aaagtatcat gtggagatag aactaaaaga gcctacagtc atttatatgg
      121 agagaccgtt aaaaaatgca gaatatacca ttcacatcga agtgccgcca aatcctttct
      181 gggcttccat tggtttatct gtatcaccgc ttccgttggg aagtggaatg cagtatgaga
      241 gctcggtttc tcttggatac ttaaatcaat catttcaaaa tgcagttatg gaagggatac
      301 gctatggttg cgaacaagga ttatatggtt ggaatgtgac ggattgtaaa atctgtttta
      361 agtatggctt atactatagc cctgttagta ccccagcaga ttttcggatg cttgctccta
      421 ttgtattgga acaagtctta aaaaaagctg gaacagaatt gttagagcca tatcttagtt
      481 ttaaaattta tgcgccacag gaatatcttt cacgagcata caacgatgct cctaaatatt
      541 gtgcgaacat cgtagacact caattgaaaa ataatgaggt cattcttagt ggagaaatcc
      601 ctgctcggtg tattcaagaa tatcgtagtg atttaacttt ctttacaaat ggacgtagtg
      661 tttgtttaac agagttaaaa gggtaccatg ttactaccgg tgaacctgtt tgccagcccc
      721 gtcgtccaaa tagtcggata gataaagtac gatatatgtt caataaaata acttagtgta
      781 ttttatgttg ttatataaat atggtttctt gttaaataag atgaaatatt ttttaataaa
      841 gatttgaatt aaagtgtaaa ggaggaatta attatgaagt gaaatgaatg taacagggtt
      901 caattaaaag agggaagcgt atcattaacc ctataaacta cgtctgccct cattattgga
      961 gggtgaaatg tgaatacatc ctattcacaa tcgaatttac gacacaacca aattttaatt
     1021 tggctttgca ttttatcttt ttttagcgta ttaaatgaaa tggttttgaa cgtctcatta
     1081 cctgatattg caaatgattt taataaacca cctgcgagta caaactgggt gaacacagcc
     1141 tttatgttaa ccttttccat tggaacagct gtatatggaa agctatctga tcaattaggc
     1201 atcaaaaggt tactcctatt tggaattata ataaattgtt tcgggtcggt aattgggttt
     1261 gttggccatt ctttcttttc cttacttatt atggctcgtt ttattcaagg ggctggtgca
     1321 gctgcatttc cagcactcgt aatggttgta gttgcgcgct atattccaaa ggaaaatagg
     1381 ggtaaagcat ttggtcttat tggatcgata gtagccatgg gagaaggagt cggtccagcg
     1441 attggtggaa tgatagccca ttatattcat tggtcctatc ttctactcat tcctatgata
     1501 acaattatca ctgttccgtt tcttatgaaa ttattaaaga aagaagtaag gataaaaggt
     1561 cattttgata tcaaaggaat tatactaatg tctgtaggca ttgtattttt tatgttgttt
     1621 acaacatcat atagcatttc ttttcttatc gttagcgtgc tgtcattcct gatatttgta
     1681 aaacatatca ggaaagtaac agatcctttt gttgatcccg gattagggaa aaatatacct
     1741 tttatgattg gagttctttg tgggggaatt atatttggaa cagtagcagg gtttgtctct
     1801 atggttcctt atatgatgaa agatgttcac cagctaagta ctgccgaaat cggaagtgta
     1861 attattttcc ctggaacaat gagtgtcatt attttcggct acattggtgg gatacttgtt
     1921 gatagaagag gtcctttata cgtgttaaac atcggagtta catttctttc tgttagcttt
     1981 ttaactgctt cctttctttt agaaacaaca tcatggttca tgacaattat aatcgtattt
     2041 gttttaggtg ggctttcgtt caccaaaaca gttatatcaa caattgtttc aagtagcttg
     2101 aaacagcagg aagctggtgc tggaatgagt ttgcttaact ttaccagctt tttatcagag
     2161 ggaacaggta ttgcaattgt aggtggttta ttatccatac ccttacttga tcaaaggttg
     2221 ttacctatgg aagttgatca gtcaacttat ctgtatagta atttgttatt acttttttca
     2281 ggaatcattg tcattagttg gctggttacc ttgaatgtat ataaacattc tcaaagggat
     2341 ttctaaatcg ttaagggatc aactttggga gagagttcaa aattgatcct ttttttataa
     2401 caggaattca aatctttttg ttccattaaa gggcgcgatt gctgaataaa agatacgaga
     2461 gacctctctt gtatcttttt tattttgagt ggttttgtcc gttacactag aaaaccgaaa
     2521 gacaataaaa attttattct tgctgagtct ggctttcggt aagctagaca aaacggacaa
     2581 aataaaaatt ggcaagggtt taaaggtgga gattttttga gtgatcttct caaaaaatac
     2641 tacctgtccc ttgctgattt ttaaacgagc acgagagcaa aacccccctt tgctgaggtg
     2701 gcagagggca ggtttttttg tttctttttt ctcgtaaaaa aaagaaaggt cttaaaggtt
     2761 ttatggtttt ggtcggcact gccgacagcc tcgcagagca cacactttat gaatataaag
     2821 tatagtgtgt tatactttac ttggaagtgg ttgccggaaa gagcgaaaat gcctcacatt
     2881 tgtgccacct aaaaaggagc gatttacata tgagttatgc agtttgtaga atgcaaaaag
     2941 tgaaatcagc tggactaaaa ggcatgcaat ttcataatca aagagagcga aaaagtagaa
     3001 cgaatgatga tattgaccat gagcgaacac gtgaaaatta tgatttgaaa aatgataaaa
     3061 atattgatta caacgaacgt gtcaaagaaa ttattgaatc acaaaaaaca ggtacaagaa
     3121 aaacgaggaa agatgctgtt cttgtaaatg agttgctagt aacatctgac cgagattttt
     3181 ttgagcaact ggatccagga gaacaaaaac gattttttga ggaaagttat aaattatttt
     3241 ccgaacgata tggcaagcaa aatattgctt atgcaacagt tcataatgat gagcaaaccc
     3301 ctcacatgca tttaggtgtt gtgcctatgc gtgatggaaa actgcaagga aaaaatgtgt
     3361 ttaatcgtca agaactgtta tggctacaag ataaattccc cgagcatatg aaaaaacagg
     3421 gttttgagtt gaagcgtggt gaacgtggct ctgaccgtaa acatattgag acagctaaat
     3481 ttaaaaaaca aactttggaa aaagagattg attttctaga aaaaaattta gcagttaaaa
     3541 aagatgaatg gactgcttat agcgataaag ttaaatcaga tttagaagta ccagcgaaac
     3601 gacacatgaa aagtgttgaa gtgccaacgg gtgaaaagtc catgtttggt ttgg
//
LOCUS       DAXLPC010000139         3652 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.144, whole genome shotgun sequence.
ACCESSION   DAXLPC010000139 DAXLPC010000000
VERSION     DAXLPC010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.144"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..885
                     /locus_tag="ACF3UE_002636"
     CDS             <1..885
                     /locus_tag="ACF3UE_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3635973.1"
                     /translation="SLVDMYVSDYFLKAEASKCITGLYTANEFNHVTPKQLDDKSVVI
                     LCSHGGNTAETVKAGEVAQARGAVTVGLTHNKTADLLKVSDHSFLYEWGDDAKIVNNP
                     MAIILDLTVSLVNVTETFEHYGKFREGMKVIDTVIENGIKQVQDRIKVFADKYKDETM
                     FYILGSGPSYGHAYGFSICSLMEMQWLDSTSVHSGEFFHGPFEVTDKDTNFILLMSIG
                     RTRALDERAKRFLDKYAERVEIVDAKELGLDMISDEVSEFFNPILFYSILSEYRSALA
                     DVRNHDLDVRRYMGKVEY"
     gene            953..1711
                     /locus_tag="ACF3UE_002637"
     CDS             953..1711
                     /locus_tag="ACF3UE_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HFD3635974.1"
                     /translation="MYPGGNSLNFAVFAKKLGHESSFMGVFGSDEEAAHVLSAIKEIG
                     LDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREYPIQLTEEDREYLNQFELIH
                     MGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAIDKVDFGFFSIEDFSDEEVKQ
                     FLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEEPVDTMAAGASFLTAFLLYF
                     LEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            1779..2489
                     /locus_tag="ACF3UE_002638"
     CDS             1779..2489
                     /locus_tag="ACF3UE_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFD3635975.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            2525..>3652
                     /locus_tag="ACF3UE_002639"
     CDS             2525..>3652
                     /locus_tag="ACF3UE_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFD3635976.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         1208 a          548 c          814 g         1082 t
ORIGIN      
        1 tcgctggtag atatgtatgt ctcagattat tttcttaaag ccgaagcatc gaagtgtatt
       61 acaggcttat atacagcgaa cgaatttaac catgtaaccc caaagcaatt agatgataaa
      121 tctgttgtca ttctatgttc tcatggagga aatacagcag aaacggtaaa agcaggagaa
      181 gtcgctcaag ctagaggagc tgtgactgtt ggtctgactc ataataaaac tgcggattta
      241 ttaaaggttt ctgatcatag tttcctttac gaatggggag atgatgcaaa aatagtcaat
      301 aatcctatgg ccatcattct tgatttaact gtatctttgg tcaatgttac cgaaacattt
      361 gaacattacg gtaaattcag agaaggcatg aaggttatcg ataccgtaat tgaaaatggc
      421 attaagcagg tgcaggatcg tattaaagtg tttgctgata agtacaaaga tgaaacaatg
      481 ttttatatct taggtagtgg accatcatat ggacatgctt atggtttttc aatttgctct
      541 ttgatggaaa tgcaatggct tgattcaact tctgttcatt ctggagaatt cttccatgga
      601 ccttttgaag taacagacaa agatacgaat tttattctct tgatgagcat tggacgcact
      661 cgtgctttag atgaacgggc aaaacgattc cttgataaat atgcagaaag agtagaaatc
      721 gttgatgcaa aggaactagg attggatatg atatcagatg aagtttctga attcttcaat
      781 cccattttat tctacagtat tctttcagaa tatcgttcag ctttagcaga tgtacgcaat
      841 catgatttag atgttcgtcg ctatatgggg aaagtggagt actaggagga ttaaaatgaa
      901 ggtattaggc ttaggtgata acgtcgtcga taaatatgaa aatctgggaa ttatgtatcc
      961 tggaggaaat tcattgaatt ttgcagtttt tgcaaaaaaa ctgggacatg aaagtagctt
     1021 tatgggagtt tttggctcag atgaggaggc agctcatgtt ttatcagcaa taaaagaaat
     1081 aggactggac aacagtcact ctcgctttga aaaaggcgag aatggctgtg ccagagtgaa
     1141 gattgatgag ggcgaccgga ttttccttgg cagcaattcg ggaggtgtta ctcgtgaata
     1201 cccgattcag cttactgaag aagacagaga atatttaaac cagtttgaat tgattcatat
     1261 gggattatat agccatgtca atcatctatt agaagagtta caaaatgttt ctggaaagat
     1321 ttcttatgat ttttctgacg actttacgga agaagaggtt cagcgggcaa ttgataaagt
     1381 tgattttggc ttcttttcta tagaagactt ttccgatgaa gaagtaaagc agtttttgat
     1441 gaagcatttt tgtgagcgaa atgatgtatt gattgcaacc cgaggagaaa aaacggctat
     1501 tggttatgat ggagcaaagt tttatgaagt gaaccccgtg ctagaagaac cagttgatac
     1561 aatggcagcg ggagcttctt tcttaacagc tttcctactt tattttctcg aaggggacga
     1621 tatagtcacc gcgatgaaaa aggggaatga atttgctggg aagtcttgtc tggttgacgg
     1681 ttcgttcggc tttggtattc attacgattg agcttgtttt aaattcctgc atttgataac
     1741 ctaaagaaag aaatcccggt aaagtggagg ttaaaaaaat gctggataca aatgcacaat
     1801 taccattgta cttacaatta aaagaaatat taaaaaataa aatcaataca ggggagtatc
     1861 ccgagaatac gaaaattccc gctgaatcag agctgataga aagttatgag gtcagccgaa
     1921 tcacagtgag aaaagcagta gaagaactgg tagaagaagg gtacctactt aaaaaacaag
     1981 ggaaaggaac ttttgtcaac cggcataaag tttttcgtaa aattgaatat attatgggtt
     2041 tcagtgagag ttgtaaatct aatggtttta caccgactag cattgttttg gaacgcaaga
     2101 tcattccagc aactgaaggg atggcaaaaa aactcgatat cgctcaaggt gatgatgttt
     2161 tatatatcca gagaaagcga atggcggata acatccccat tatgttagaa aacaattatt
     2221 tttcttatga aagatatagt ttcttaatgg aggaagagct gactgattct ttgtatgaag
     2281 tacttaaagt ccaaggtacc ttagccatca atcctgggga aactgcactt gaaattgtca
     2341 cagctgatga ccaaattgcc aaaataatgg aagtagctgt tgggacgccc tttttcttta
     2401 tggatacttt aatcaacgat caaaacaaca taccaattca tgtaggtaat caatattacc
     2461 tgggagaagt atatcgtttt tacttatgat ttcctgtttg gatttcaagg agtagatttt
     2521 atttatgaag caaatattgc ggtcaaaaat gatttttgat ggagagcagc cacctttcaa
     2581 aggttatatt gtaatcaatg aagggatcat tgaaaaggtg gaaaacaact ggaattacag
     2641 tgatctatta aatgaaaaca cggaattaat tgcttatgat gatcaattcg ttatgccagc
     2701 aattcatgat aatcatgtat ttttcagtgg ttatttggct atgaatgctg gcatagattt
     2761 aagcgataca tcttcagcta acgaggctgt agagcgtatt aaagctgtaa tgaaccataa
     2821 aaaagcagat gaaccaattt atgctcatgg ctgggatgct gccctgtgga aaactgaccc
     2881 atcagaagag ctattgaatg aaataaacca ctttggtcca atcacagcga tcgacaaaaa
     2941 tcgcagccat tgttggatga atgctattgc taagcagact tatggtttta cagaaaaaga
     3001 aaccagtgct gaaagtcgag tattattaat taaggaaatg ctagcaaaca aaaagctttt
     3061 agcagaggtt tacgctgaat ttgaagcatt actgctttca aaaggtgtta tatcaatgaa
     3121 agaaatcgtt tttgatgacg cagaatttct ttctaatata cctcagagga aaatacttag
     3181 taacctatat gtgcaggcag tccaagaacc tctacagcat gaacttctat atgagtataa
     3241 ggaaaaagtt ttccctgaaa aggtccgctt tggtggagtg aagatcatgg tagatggtgt
     3301 tgttgcggat agaagtggag atatttacgg tgtttatcag tcaggagtag cttcacccga
     3361 gattgactat gaggcaatta aagcagaagt tgctgcattc aatgaagtag agattccttg
     3421 ctgtttgaca acggaaggag ataaagcggg ttataaagct gcgtcaattc ttgtcgaatt
     3481 tggaaagcgg ttacctgaag gcgtttttaa ttcgattagt gatttggaaa tggttactca
     3541 aaagacagca gaaaaaatga acgaaggaca agtagtagca gaggtatatc cacaaattct
     3601 cggcttgaat caaacgttag aagaggctta catgtcaact gttataaaaa at
//
LOCUS       DAXLPC010000140         3632 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.145, whole genome shotgun sequence.
ACCESSION   DAXLPC010000140 DAXLPC010000000
VERSION     DAXLPC010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3632
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.145"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            647..964
                     /locus_tag="ACF3UE_002640"
     CDS             647..964
                     /locus_tag="ACF3UE_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFD3635977.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="ACF3UE_002641"
     CDS             complement(1055..1420)
                     /locus_tag="ACF3UE_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635978.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="ACF3UE_002642"
     CDS             1628..2110
                     /locus_tag="ACF3UE_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635979.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /locus_tag="ACF3UE_002643"
     CDS             2307..3197
                     /locus_tag="ACF3UE_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFD3635980.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(3484..>3632)
                     /locus_tag="ACF3UE_002644"
     CDS             complement(3484..>3632)
                     /locus_tag="ACF3UE_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3635981.1"
                     /translation="AFKVSHSNGVTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGL
                     IFEN"
BASE COUNT         1235 a          567 c          670 g         1160 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac tttttttggc tcttcgtcaa atcgtgttgg
     3421 tgaagacaaa tttgaataaa acttagtccg atatgcggcg cgttctgtgc gccgcatatt
     3481 tttttagttt tcaaagatca gaccttgttg taaatagatc cgtgcccgaa agttataaaa
     3541 gttgcgataa ccaaacgcaa ttcgtttaat cagcttgatc ttgttattca gcccctcagt
     3601 gacgccgttt gagtgggaca ccttaaaggc at
//
LOCUS       DAXLPC010000141         3567 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.146, whole genome shotgun sequence.
ACCESSION   DAXLPC010000141 DAXLPC010000000
VERSION     DAXLPC010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.146"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            790..2340
                     /locus_tag="ACF3UE_002645"
     CDS             790..2340
                     /locus_tag="ACF3UE_002645"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFD3635982.1"
                     /translation="MSDKNTYARRSQRHKQEPDSCENTNQLNEAVKPQTGNENKQPKI
                     PKKKSNYSKYIFALFTALILVIVVTGGYIVYTLKQQEAEAQAKYETAAKNLMASIQEE
                     QDQSGISTKIDTINDGENKCLVYRPVDENTVPFKNANQLLDELAQKQQKKHREKEVLT
                     VARIKATAISSKVNQYRIEADSFIWDRSKENFKKPDSISEKDIYIFKKTGKEITNKDL
                     FPDEGSLLGIQQVIQQSILDQAKEPEKIIDAVLTMDRISYDSKMTYTPDELTIVLPKN
                     STGTSKVTLKYKDIAPFIDTDLVSQESIKDTLPALDENKKYVALTFDDGPNNSSTLDL
                     LNILKTDNVKATFFMLGQMVDQNPDVAKQVHDEGHEVACHSYSHPQLNTLSTDELQSE
                     INKANKAIFKATGVLPRNIRPPYGAIDKKSAETIGMPIIQWDIDSQDWKSKNPRAINN
                     VVKQNVYNGAIILIHDIHPESVKAIPNMISMLKNKGYEFVTIDQLLSGKQKPLHQYFG
                     MNDERLVD"
     gene            2625..2844
                     /locus_tag="ACF3UE_002646"
                     /pseudo
     CDS             2625..2844
                     /locus_tag="ACF3UE_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1347 a          520 c          571 g         1129 t
ORIGIN      
        1 ttttttgttg atttaccaac atgtttagac attttcctct aggaaaaaat taactagcac
       61 cacgggtttt tgtactatta attgtgattt ttaaatgatt gaaaaataga gaggaggaag
      121 caatacgtag aaaaaatatt ttaaattggt gtaagtacaa atatgttatt tacagtattt
      181 tagtttctcg tattaagtgt tactactatg gtgaattctt tagagaatta ataaatagtc
      241 ttctttgata gattgttaaa gggaacttaa caaagtaata agatgcataa tcaaatgcac
      301 aaaaaacaaa aaaagaagtt tcttcgaata gaaattctga aataacatcc tttcgcctaa
      361 tagtgaataa tttaaataaa gagaaactgg ctacactatc aaagcaagtg attctgttta
      421 gctaattact aataattaaa gtattaaaat agtatgttta atcaaataga acaagattgg
      481 ataatagttt atatttttaa tcctagacca ttattggtat ttcaaagact acaaccatac
      541 taattaatct atcgaatggt acaatttcaa aaactaaaat caaaactagt gattctaatg
      601 ttatcaaaac tgagttgaaa attaagtagc cacaatatct aaagtggtga ggaattagcg
      661 ataattacta cgccgaaagt aaaagaataa tagaaaaaac tttccttaaa aattatctat
      721 gaattcgttt tcattataat tgcgctgttt tattttactt tatgatgata aatggaggga
      781 taaagtcata tgtctgacaa aaatacctat gcacgtcgta gccaacgtca caaacaagaa
      841 cctgatagct gtgaaaatac aaatcaattg aatgaagctg taaagcccca aaccggaaac
      901 gaaaacaaac aaccaaaaat accgaagaaa aaatctaatt atagcaagta tatattcgca
      961 ttgtttaccg cacttattct agtaattgtc gttactggcg gctatattgt ttatacatta
     1021 aaacagcaag aagcagaagc tcaagccaaa tatgaaactg ctgcaaaaaa tctcatggct
     1081 tcaatccaag aagagcaaga ccaaagtgga atttcaacga aaatagatac tataaatgac
     1141 ggagaaaata agtgccttgt ttaccgtcca gttgatgaaa atactgttcc tttcaaaaat
     1201 gcaaaccagc tcttagacga gcttgctcaa aagcaacaaa aaaagcatcg tgaaaaagaa
     1261 gtgctcacag ttgccagaat aaaagcaaca gcaatatctt ctaaagttaa tcaatataga
     1321 attgaagcag atagttttat ctgggatcgc agtaaggaaa atttcaaaaa gccagatagt
     1381 atttctgaga aagatatcta tattttcaaa aaaactggca aagaaatcac aaataaggat
     1441 ttgtttccag atgaaggaag tctcttaggt attcaacagg tgattcagca atccatactt
     1501 gatcaagcca aagaacctga aaaaatcatt gatgctgtat taacaatgga tagaatttct
     1561 tatgatagta aaatgactta tacacctgat gaattgacta tcgtcttacc aaaaaattca
     1621 actggaactt ctaaagtcac tctaaaatac aaagatattg cgccattcat tgatacagat
     1681 ctggtttcgc aagaaagtat aaaagataca ttacctgcat tagatgaaaa taaaaagtac
     1741 gtcgctctta cttttgatga tggtccaaat aatagctcaa cacttgattt gttgaatata
     1801 ctaaaaacag ataacgtgaa agctactttt ttcatgttag gacagatggt ggatcaaaat
     1861 ccagatgttg caaaacaagt ccacgacgag ggtcatgagg tagcatgtca ctcgtattct
     1921 catccacaat tgaatacact ttcgacagat gaattacaaa gtgaaataaa taaagctaat
     1981 aaagcaattt tcaaggctac aggcgtcttg cctcgcaata tccgtccccc ttatggcgct
     2041 attgacaaaa aaagtgctga aacaattggc atgccaatta ttcaatggga tattgactca
     2101 caggattgga aatcaaaaaa tcctagagca atcaataatg ttgtcaaaca gaatgtttat
     2161 aatggtgcaa tcatcttaat ccacgatatc catcctgaat cagttaaagc cataccaaat
     2221 atgatctcca tgttaaaaaa taaagggtac gaatttgtga cgatcgatca actattgtca
     2281 ggaaaacaaa aaccattgca tcaatatttt ggtatgaatg atgagcgact agtagactaa
     2341 ctgtaattag attgagtggt atttgaagaa attatatttg tagtttcctt atttgatgaa
     2401 aagtcatgta aaacaaatta ataaagagta ttaagtatac taactgttgt aagtatactt
     2461 aatactcttt tagttattaa ctttagttag tctcgttagc gtagcgtacg aaacaaaaaa
     2521 acacgcattt ctgtgcgtgg acgaaatagc tttagcgata aaaaactcct ttcgatatac
     2581 taataatggc tactaaccgc atatcagatc gaaaggagtt tctaatgttt accgacgata
     2641 aaagtgtagc acatacgaga tgtcatattt tctttaccca aagtatcgac gaaaagtgat
     2701 ttatggaaag ttaagagtag gtattggtca gatattaaga aaattgtgtg agatgaaaaa
     2761 tattgaaatc attaaagctc atgttatatt catttgttag taagaataac gtcaaaaatt
     2821 agtatttcca gttttatggg ttactaaaaa gacgtcactg atcaatttag aaaggtaaat
     2881 atattctggt aataaagata gactgaaccc cgtaaaaacc tcattgcaac gaatcaagga
     2941 aagacgcttt tgcttctccc ttgattgggc acattctttg attttgattt ttgatattga
     3001 ttatatcttt taattcgcca tagttattta tacaataaag aactaaattt tctaagaata
     3061 gactttctag attctttatt ttcagctttt actaaaatga agtcatccta tccattttat
     3121 tcaaaacaaa ttttttaata agaaagatct gttctttttc tttgaaggaa aagaaaaaga
     3181 aaacgtgaaa agaaacttat gcaatctata ctgctaataa cctctataag atcgttgtat
     3241 attgatatta ttatcatgtt tattttagga agaatactat gagttaagtt tttaataaga
     3301 aatgtcgagt ttatgaacct tttttcaaag ttgaaaaaat ttctttattt gataatggcg
     3361 atcaacatct tttagaatgg atgcaatggt taaactgatt gttgagtata taatcacttg
     3421 tttgttttta tttatctttt ccccactata tggttaatag tcagccactt tagaaagagt
     3481 tttagctgtt ttttacttga ggaacatcat tttattggca gtcttatttg acttattaag
     3541 tgaatttata ttaaaaaaat tcgtttt
//
LOCUS       DAXLPC010000142         3542 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.147, whole genome shotgun sequence.
ACCESSION   DAXLPC010000142 DAXLPC010000000
VERSION     DAXLPC010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3542
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.147"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..342
                     /locus_tag="ACF3UE_002647"
     CDS             <1..342
                     /locus_tag="ACF3UE_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HFD3635983.1"
                     /translation="SWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGLHDQ
                     LEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMIRKR
                     LLLEAEKAVKE"
     gene            339..2658
                     /locus_tag="ACF3UE_002648"
                     /pseudo
     CDS             339..2658
                     /locus_tag="ACF3UE_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
     gene            2719..3261
                     /locus_tag="ACF3UE_002649"
     CDS             2719..3261
                     /locus_tag="ACF3UE_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635984.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            3339..>3542
                     /locus_tag="ACF3UE_002650"
     CDS             3339..>3542
                     /locus_tag="ACF3UE_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635985.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWR"
BASE COUNT         1299 a          514 c          708 g         1021 t
ORIGIN      
        1 tcgtgggata tcaatgatat agacatacat tgtacacatg cggacttgga tcttaaggct
       61 ttacaaattg attatgatta tttcctacca gatgaatatg ctagaaatct ctatcatgga
      121 ctgcatgatc aattagaaga aaaaaacgaa gaaaatatgt tttataaaat cgttcaatct
      181 tttgagaatg agacggctaa aaaattgtta attcaatttt acgaagaaca agcaacggat
      241 cgtcttcaag aatatgttga aaagttgatc aaaaatgaag aaatttctga aatgattagg
      301 aaacggctgt tattggaagc tgaaaaggcg gtgaaagaat gatcattgga ggaattttct
      361 ctggcatagc cgactggtgg tcaggtttat tcggagaagg ggatgcagat cccaaaaccg
      421 taacgaaagt cttacaagat tatggtaatt atctgcagta tcaagatgta ttcagttgga
      481 tttgtaatac ttttttatgg ggattgatca aagggttata taatctcaat actttattag
      541 aaaaaacaat ttatcaaagc tttgatttaa aagacttatt gaacgccgct ggtgttaatg
      601 aactatttca aagtttgatt agtaaggtat tggctctttt ttgtgtcgtc acattaattt
      661 atttaggctt gaaatttttt atgagtaaac acccaccgaa agtcaaaaat atcttggtta
      721 atttatttat ggccatgatc ttgatttttg gtggtagttc tttaatcgat gaagggttaa
      781 atatcagtaa aaacttttat ggagacgtca ctgcagcaaa taaagcagat aaaacgggtt
      841 cacctgcttt tcaaattatt caaaataatg tgattgatgt cagtacatta ctagcgactg
      901 acccgaataa agtagaatcc ttaccaacag ataaaagaaa tgctttaaca gcgaaaaatt
      961 tcaaaacagc gaatatcaat gggattatta cacctgatca agctaagaaa atgtctgaat
     1021 caagtgatat tagtacagta caaaaagatc ggttaaaggc attacagtat cgactagagt
     1081 tagacgataa tgggaaagaa atccctgttc aaattagtga tgaaggttta gcaaaatatg
     1141 tgtatacgtc aggctatcgt cgatacatta gtagtccagg gattattttg gctggggaat
     1201 cttctttgtc ggtagcctat ttatttattt tgtttacaat cgttacttgc attattgagc
     1261 tagtatttaa aaaattctat ttagtaattg ccgcgtcaac ggactttgag acaggacaac
     1321 ggatgaaaag tgcgatagaa gatatttctc aatccttctt gttattggcg tttacgattt
     1381 tagaattacg aatctataca ttaatgcttt caggtatcgg tgatttgcat gcggtaggaa
     1441 agatcaatgg attcttgtat gttgttgctt taattgtgct aactattgcg ctattcaaag
     1501 gctctcaatc ggttacgaag attttcggtg ttgatacgag tctgaaaaac ggcagcaatt
     1561 ctcttcttag catgtttgcc ttaggaaata ttgcgaaaaa tgtgggtagc ggagctaaaa
     1621 accttgcaag tgctggtaag agtggtttaa gccatttaaa tgatattcgt aagaatggat
     1681 ttggccatcg aaaagatatt acccatgata acggggaaga acaatcagac gataaagcta
     1741 caactgtacc taatagtaag aagacagttt ccgaaatgtt cgggaaagcg aaaaatggtg
     1801 tttctaaagc cgcagaaggt cttggttacg tcaatgaacg tgggttaaaa ggaacagttg
     1861 aagatcttac agaaaaagcc aaagacacct tagaagagaa attagacggc acgagagcta
     1921 aagaatttgc tgaagctgtg aagaatccat ccgaagcact agaaaaacaa aaagaaaaag
     1981 cttcagcagt caaagaagga ctaaaagatg cgtatggtga aggacaagtc aatgcagcag
     2041 tgaaggcaaa tacaacaagt gaaaaagaaa atcaagaagg tgcagcgatt ccttcagcca
     2101 aagatcacca agatgagtta cattctaacg aaaattcgat cggagaaaaa gattcagaag
     2161 aaggacaaca tggtcagtta ccaaaaaccg atccagaaca atatcgttat aaatctaaca
     2221 ttaattctga aaacgaaaaa cgcatttcag atttaccaaa acgaaatcaa gaagtacaaa
     2281 cggatgagga ttccatcgat ctgccaaatg ataatggcat cgaagttgga actgaaaaat
     2341 caacgaaaat tggtttgcct aagacacaaa atttaccaat gaaagggtac tgttcaaatg
     2401 aaatcaagtc gtttgcctga aaatggaaat ctgacaactg tttcttacaa tttagctgaa
     2461 agtggtgaaa cagagaatgc gtccgttcaa aatattgtga caaaagaagc tgcacctaag
     2521 ccaatcaata aagttcataa tggatacaga ccagcaaacg tagcatttac tgcaccgaca
     2581 aaaataaatg tgacaagaga aactaaaaac aggaacaatg aattgaaaga acaactattg
     2641 aaggatatca aaccataaaa ggcctattta agggcctttt tctttataaa acaagtttaa
     2701 aatggaaagg agaaaattgt ggaggatatt ttaatagcta cgtttataac tgcactggga
     2761 gcatttttaa cgatatttgt ggtgactatt aaaggattta aagatacgga tagtttacaa
     2821 aaagatcatc agtctatttt agatggtcaa aaaacacata ccgaaagcat tattgtacac
     2881 ctttcagaag gattcactta tttgaaagat gctatgccca cattcacagt aaaattaacg
     2941 gaaatatttc attctgttga gcaaatatcg tcagaattga aagagcaaag acaacaaaaa
     3001 gatcgtcaac ttggctcact taattttagg caagaaacga tacaagaatc attggagaat
     3061 gtaaatcgat taaacgatga aatgcaacga gttcatttgg aaaatgaaga attacgcgca
     3121 caaaattatg atttaattca aaagaaaaga aatctggaac aaaaaattgt tgaattaaaa
     3181 gaagaaaatc gtcaattgaa ttatcaatta cgacgaggaa aaaatcgttc tcgtgattta
     3241 ggaaatgaat tagagttgta atatttagaa aaacgctgtg agaaatcaca gtgtttttta
     3301 tttctaaaaa tacaaaatat aaggggtatg gttatattat ggataaatac attcatatga
     3361 aaaatcctcc aagatttagt ggggaatgga agtttttcgc ctttttcttt ttagatctat
     3421 taacgcttgg tggctgcttt ttttgggcga aaatagtcaa taatcttgtc cacttaccac
     3481 tcttttttgc actcttgaat tatggattat ggcttgcgat agcgttagtg attgtttggc
     3541 ga
//
LOCUS       DAXLPC010000143         3481 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.148, whole genome shotgun sequence.
ACCESSION   DAXLPC010000143 DAXLPC010000000
VERSION     DAXLPC010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.148"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            424..1695
                     /locus_tag="ACF3UE_002651"
     CDS             424..1695
                     /locus_tag="ACF3UE_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HFD3635986.1"
                     /translation="MNVFDATLKRLEYIFEEFDKVYFSFSGGKDSGIMVQLANLVAEK
                     LDRNFDLLILNIEANYTATVDFIKKIEQLPRVKNIYHFCLPFFEDNNTSFFQPQWKMW
                     DPSEKEKWIHSLPKNAITLENIDDGLKKYYSLSNGNPDRFLRYFQNWYKEQYPQSAVS
                     CGVGIRAQESLHRHSAVTKGENKYKNRCWINITLEGNILFYPLFDWKVDDIWAATFKC
                     GLEYNYIYEKMYKIGYKYRDMRICQPFGLQQRKALNQFAELEPETWDKLVKRVSGVNF
                     GNIYGKTSLLGLNTSQKPSFMTWQRYSIFLLETLGLYSPLLMNHYYRKICILFAYYKN
                     KYNMDIQDMPDESKRKDWIKDERLWNDWKGIAKALEKNDFVLSTRNYSLTKKDEAELY
                     EMFKEYKDFLGINQLKGKRYENIVQKIGGMK"
     gene            1692..2117
                     /locus_tag="ACF3UE_002652"
     CDS             1692..2117
                     /locus_tag="ACF3UE_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635987.1"
                     /translation="MSEIDIKVYIPPYNKQNFYSLMGKYFAERVYRRKLPYLINTPST
                     IWFLLMNKERIIGFSSIQISNEFIDIGDVFVEDENDDTRKYLLEKVLFFIDKKCERKC
                     VRISLKKDQYLNNLKHYCFKQYRETKNYLFFRREINEQD"
     gene            2104..2637
                     /locus_tag="ACF3UE_002653"
     CDS             2104..2637
                     /locus_tag="ACF3UE_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA];
                     GO_process: GO:0043170 - macromolecule metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043412 - macromolecule modification
                     [Evidence IEA];
                     GO_process: GO:0044238 - primary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IbrB-like domain-containing protein"
                     /protein_id="HFD3635988.1"
                     /translation="MNKIDMPVLNVKMVPVEKIKSNNYNPNHVAEPEMELLELSILKD
                     GYTQPIVCYYDDKKDEYIIIDGFHRYLIGKSKLDLKELPLVVIDKPLEQRMSSTIRHN
                     RARGKHEIDKMSELVLLLVNEGWDDHKIGKELGMEKEEVLRLKQVTGLKSAFLNHEFS
                     ESWDEFVKKNYPKQKDE"
     gene            2771..3238
                     /locus_tag="ACF3UE_002654"
     CDS             2771..3238
                     /locus_tag="ACF3UE_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFD3635989.1"
                     /translation="MKFCETKKVLNQLVADLSVFSVRIHQVHWYMRGERFLFLHPKMD
                     DLMEQINDQLDVISERLITLDGSPYSTLEEFFTNSKLEEEKGSWNKTIDEQIDYLLEG
                     YNYLVSTYEEGIETAGKEGDDCTEDIFIGSKSELEKEIWMLKAELGNSPELDK"
BASE COUNT         1352 a          361 c          597 g         1171 t
ORIGIN      
        1 gatgcaactc ctgttttcag tcgactaatt ctccactttt tgataattgg attgcttttt
       61 aattctaata actttttatt gttttttcca accataaaat tatcctttct acataattta
      121 ttcgaacgat aaaaatgatc gttcattttc attataataa tatttaatgg aaaaacaagt
      181 taaaaatatt gtttgaataa taattccaat tatttctata atatttgtta actgtaagat
      241 actactagac taaaatccat ttttgttttt ttaagtaagt atagtatata aattaaaggt
      301 gttccttaca ttattctata tgatttgaat actataagaa acaacaattg ataaaattat
      361 tgacaaagtt tttaaaggta ttaccattga tattgaacgc ttattttttt agggggatga
      421 gaaatgaatg tctttgatgc tactttaaag agattagaat acatatttga agaatttgac
      481 aaggtgtatt tttcatttag tggtggtaag gatagtggga taatggttca gttagctaat
      541 ctagttgcag aaaaattaga tagaaatttt gatctattaa tattaaatat tgaagcaaat
      601 tacacagcaa ctgttgattt tataaaaaaa attgaacagt tacctagagt aaaaaatatt
      661 tatcattttt gcttaccttt ttttgaggat aacaacacta gtttttttca acctcaatgg
      721 aaaatgtggg atccaagcga aaaagaaaaa tggattcatt ctcttcctaa aaatgccata
      781 actttggaaa atattgatga cggtttaaag aaatattatt cattatcaaa tggtaatccc
      841 gacagatttc ttcgttattt tcaaaattgg tataaagaac aatatcccca aagtgctgta
      901 tcatgtggtg taggtataag agcacaagaa agtttacata gacatagtgc tgttacaaaa
      961 ggtgaaaata aatataagaa tcgatgttgg ataaatataa ctttagaagg aaatattttg
     1021 ttttatcctt tatttgattg gaaagttgat gacatttggg ctgcaacttt taaatgtgga
     1081 ctagaatata attatatcta tgagaaaatg tataagattg gatataagta ccgggacatg
     1141 agaatatgtc agcctttcgg attacaacaa agaaaagcgt taaatcaatt tgctgaactt
     1201 gaacctgaaa catgggataa attagtaaaa agagtaagtg gagttaattt tggaaatata
     1261 tatggtaaaa ctagtctttt aggattaaat acttctcaaa aaccttcatt tatgacttgg
     1321 caaagatatt ctattttttt actagaaaca ttaggattat attctcctct tttaatgaat
     1381 cattattaca gaaagatatg tattcttttt gcttattaca agaataaata taatatggat
     1441 atccaagata tgccagatga atcaaaaaga aaagattgga taaaagatga aagactttgg
     1501 aatgactgga aagggatagc taaagcttta gaaaaaaatg actttgtttt atctactaga
     1561 aattatagtt taacgaaaaa agatgaagct gaactatatg agatgtttaa agaatataaa
     1621 gactttttgg gaataaatca attaaaagga aagaggtacg aaaatattgt acaaaaaata
     1681 ggaggaatga aatgagcgaa atagatatta aagtttatat acccccatac aataaacaaa
     1741 atttttacag tttaatgggg aaatattttg ctgaaagagt atatagaaga aaattacctt
     1801 atttaataaa tacacctagt actatttggt ttttgttaat gaacaaggaa aggataattg
     1861 gattttcttc catccaaatt tccaatgagt ttattgatat tggagatgtt tttgttgaag
     1921 atgaaaatga cgatactcga aagtatctat tggagaaggt tttatttttc atagacaaga
     1981 aatgtgaaag aaagtgtgta cgaatttctt taaaaaaaga tcagtactta aataatctga
     2041 aacattattg ttttaaacaa tatagagaga caaagaatta tttatttttt aggagagaaa
     2101 tcaatgaaca agattgatat gcctgtttta aatgtaaaaa tggttccagt agagaaaata
     2161 aaaagtaata attataaccc aaatcatgtc gctgaacctg aaatggagct tttagaatta
     2221 tcgattttaa aagacggata tacacaacca attgtttgct attatgatga taaaaaagac
     2281 gaatatatta ttattgatgg gttccatagg tatttaattg gaaaaagcaa acttgattta
     2341 aaagaacttc ctttagttgt aattgataag ccattggagc aaagaatgtc aagtacaatt
     2401 agacacaata gagctagagg gaaacatgaa atagataaaa tgtccgaatt agttctactg
     2461 cttgtcaatg aaggatggga cgatcataaa atagggaaag aactaggaat ggaaaaagaa
     2521 gaagttctta gattaaaaca agtaacaggg ttgaaaagtg cctttttgaa ccatgaattt
     2581 agtgaatcat gggatgaatt tgtaaaaaaa aattatccta aacaaaagga tgaataagtg
     2641 gtaaagattt ttataaacac gattttaata taaacgttca ttttattgtt gacaagatat
     2701 atttgttata ttaaattatg tgtaaatcag aattatttct tttaaaaaaa tttaaattag
     2761 gagtgatatt atgaaatttt gtgaaacaaa aaaagtatta aatcaattgg tagccgattt
     2821 aagcgtattt tcagtaagaa tacatcaagt tcattggtat atgcgtggag aaaggtttct
     2881 atttctacat cctaaaatgg atgatctcat ggagcaaatt aatgatcagt tagatgtaat
     2941 ttcagaacga ctgattacac ttgatggatc tccgtattca actctagaag agttttttac
     3001 aaattccaaa ttagaagaag aaaaaggctc ttggaataaa actattgatg aacaaattga
     3061 ttatttattg gaaggttata attatcttgt ttcgacatat gaagagggga ttgaaactgc
     3121 aggaaaggaa ggcgatgact gtacagagga tatttttatt ggttctaaat cagagctaga
     3181 aaaagagatt tggatgttaa aagcagagtt aggtaactca cctgagttag ataaatagat
     3241 acagaacttc aagtgaatgg ttatgatatt tccttgtgaa tagggagtgt ttttcagtgt
     3301 ttctatgaat actataagtg agattgataa aaaaacaaaa acatctaagg agagatttat
     3361 ttctacctta gatgtttttt cactaagtga tctgtttcag tcgataaata taagtgcagg
     3421 tagattttaa caactaatta tatcaaagaa ataagtatat agtactgtaa aaatatatat
     3481 t
//
LOCUS       DAXLPC010000144         3420 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.149, whole genome shotgun sequence.
ACCESSION   DAXLPC010000144 DAXLPC010000000
VERSION     DAXLPC010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.149"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            53..664
                     /locus_tag="ACF3UE_002655"
     CDS             53..664
                     /locus_tag="ACF3UE_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFD3635990.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            737..1666
                     /locus_tag="ACF3UE_002656"
     CDS             737..1666
                     /locus_tag="ACF3UE_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HFD3635991.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1803..2561
                     /locus_tag="ACF3UE_002657"
                     /pseudo
     CDS             1803..2561
                     /locus_tag="ACF3UE_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033645.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
     gene            complement(2609..>3420)
                     /locus_tag="ACF3UE_002658"
     CDS             complement(2609..>3420)
                     /locus_tag="ACF3UE_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFD3635992.1"
                     /translation="MYGHHYTPQTMSNMTKSFTEEVTSFKERELHDRYAAIYMDATYI
                     PLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERGVKNVLLF
                     ITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMVYQASSKK
                     AALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIESFNKQIK
                     KYSHRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE"
BASE COUNT         1123 a          533 c          660 g         1104 t
ORIGIN      
        1 gaagtttata tgaagttata aaatttaatt tatattggaa ggaggaaaat aaatgtattt
       61 tatactacct acactttata gccttttatg tgtaatggca ccatgtatta tttatatggt
      121 atttttttgc aaaaaaaata ccctgaaaca caatatcctg attttgattt ttatgctgta
      181 ctgttggaaa gtttttgaat tgactggtac aggtggacta acagatattt tttatagacc
      241 tgatacaggt aggaaatttt ctctagtaca gggcagtgtt aatcttgtac cattcagtgg
      301 actaaacatt agctttatat taaatatagt aatgtgtgtg cccttaggat tcttactacc
      361 aatcatatgg aaaagttata ggaaaatagt tcctgttttc ttggctgggg ctctattttc
      421 actaattatt gaagtctcac aaattataac tacaagagca acagatattg atgatttaat
      481 agcaaatacc tttggtgcgg ttataggctt tatactgtgg gctgttttaa gtagagtggt
      541 gtccttgaag gacaagtcat ctacagtaga ttatttagaa ccttatattt atatattgat
      601 tggttttacc ggaaaattct tactgtattt tcctttctgg tttgcttttg aagtattatc
      661 ctgataattc catagaaaat aatgagtttg agttgagaaa gaatattctt gtacacaact
      721 ctggaaagga ggaagtatga aaagattctt aaaatggggg cttgttcttt tagcgtcttt
      781 gattgtgatt ctaatgtgta cagcggttgt tatttcttat gtgaatcggc cgtatgcaag
      841 agctgtttat gataggatta aacgcattct tgacaaagat ttttatgacc atctatatct
      901 aggttcttca tttgaaataa taaaccttga tacaatggat attcatagct atatgaaaaa
      961 agaccaagaa gaattacccg cctcattgag caaattattt acgattgatt atgcgcttag
     1021 tgtcctaagt ttagatgaac agattacaat tagtcctact gcacttgaca tgcagaaagc
     1081 tgactcatct actgcacatc ttcaagaagg agatatttta tctgtttatg acattatctg
     1141 tgctatggtc ttaccctcag gaaatgatgc agcttatagt ttggcaattt atacaggtgg
     1201 aaaacttgat cctgatgcaa agaatgatga agaacgctat caaagcttca tgaaaaactt
     1261 agatcgttat ctaagtgagc aaggctataa acatactcat tttactgacg ctgctggcta
     1321 tgactccaat gctacaacat cagcggaaga tttgacaaaa gtagctgcaa agctactaaa
     1381 gaatgataaa tttgcagaaa tagttgccaa ggaaacttat agagcaaaat caattaaggg
     1441 aaatgtttat aactggaata ctacgaatca atttatgcaa caagataata gatactttac
     1501 tgaaggtgta aaaggtgtaa aaactggatc gtttgatggg agatacaatc tatgtgtgta
     1561 ttatacatct agttctgata accactattt acttgtaagt tttggttcag agagtgatag
     1621 taggcgttat gtagatgttc aaaatctatt gcataatctg ccttgaaatt tcgtgccttt
     1681 aagcgcgtat ctaaagtttc tttgaaaagt ttgagaatga agaaagtgag cagtcgaaaa
     1741 acggttgctc acttttttgc cctaaaatcg aaaaaatata aaaaagtcct ttacaacacg
     1801 tctcaggaaa aactgctaag tcaattctaa tatcttgtgg agcaagactt gcaccttttg
     1861 atataagaga gcttagagaa ctaatgagcg aagatgaact agaactcgat aaaattggag
     1921 atagaaaaac tgccttgttt gtaataatat cagatacaga tgatacattt aattttgtag
     1981 tttcaataat gtattctcaa ttatttaatc tactatgtga taaggcagat gatgtgtatg
     2041 gtggaagact tccagttcat gttaggtgtc tacttgatga gtttgcaaat atcggtttga
     2101 ttcctaaatt tgaaaaacta atagcgacaa ttcgttcaag agaaatatcg gcaagtataa
     2161 tactgcaagc acaatctcaa ttaaaagcaa tttataaaga ccatgcagat acaatagttg
     2221 gtaactgtga ctctacactt tttctaggag gaaaagaaaa aacaacagta aaagaattat
     2281 cagaaacctt aggaaaagaa accatagacc tatataacac atcagaaaca agatcaaatc
     2341 aaaaatcttt tggtctaaat tatcaaaaga ctggcaagga acttatgagt caagatgaaa
     2401 taactgtaat ggatggtggt aagtgtattt accagctaag aggagcaaga ccttttctat
     2461 ctgataaatt tgatattaca aagcataaga attacaaatt gttggaagat tatgataaga
     2521 aaaacttgtt tgatgtagaa gagtatttaa aacaaagata gcgtaaaata ttttgtgtaa
     2581 ataactcgtc cttctgcaaa ataatgggtt actcagtaaa cattgaagct aatgtatccg
     2641 tcacttgttg gaagccttta tggcttctat ttaagaattt ttgattgtat gtatcaaaga
     2701 tggatactag gaaacgctct agtgattctt cattttgaaa ctgctctttt ctgtggctgt
     2761 atttcttgat ttgcttatta aaggattcaa tcaagttcgt agagtaaata gtcttgcgta
     2821 tggctaatgg aaaatcatag aaagtgagca ggtaatcgtt cgaaaggatc gattccacca
     2881 tttttggata actggttttc catttttccg caaaagcacc acgtgcttcc aatgccgcct
     2941 ttttagatga cgcttgatac accattttaa aatcatcaca gacttcctta cgatcatcga
     3001 cacgcacttt gtgactgata ttacgggaaa cgtgcacaca gcaatgttga aaacgggctt
     3061 tggggtagaa ccgctgcacg gcccctgcca tcccctttaa gccatccgtg atgaaaagga
     3121 ggacgttttt cacgccacgt tcctggaggt ctattaaaat ctcttcccaa atcgtgatag
     3181 attcagttgg tgcaatcgca tagctcaaca cttcctttga accgtccggg cgaatgccaa
     3241 ctgcgatatg aatggcttcc ttggcgacgg ttttccgctt taaagggata taggttgcgt
     3301 ccatataaat agcggcataa cggtcatgaa gctcacgttc cttaaatgaa gtgacttctt
     3361 ccgtaaatga tttagtcata ttggacatgg tttggggcgt gtagtgatgc ccatacattt
//
LOCUS       DAXLPC010000145         3328 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.150, whole genome shotgun sequence.
ACCESSION   DAXLPC010000145 DAXLPC010000000
VERSION     DAXLPC010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.150"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..354
                     /locus_tag="ACF3UE_002659"
     CDS             <1..354
                     /locus_tag="ACF3UE_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HFD3635993.1"
                     /translation="RATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSS
                     LETPSISAKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKLESLQ
                     PPIPPIPKTPKLPGL"
     gene            791..1108
                     /locus_tag="ACF3UE_002660"
     CDS             791..1108
                     /locus_tag="ACF3UE_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635994.1"
                     /translation="MEKTKKLQLEDFTENEFFGTQEQQYLKAQVREELKEQGFIIDSS
                     FEGDFKTWIGVYARPKDKPTYLDPQNDKEAEEQEQYSINGFKQDFSEWFEWEIKNLKI
                     KEM"
     gene            1147..1644
                     /locus_tag="ACF3UE_002661"
     CDS             1147..1644
                     /locus_tag="ACF3UE_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="HFD3635995.1"
                     /translation="MKYIKNVETLEELKKAYKKLALKLHPDCGGSNEEMAQLNNEYDE
                     LFVKLKNTHKNKDGETYTKETTETPEQFKDIINQLFNLKMDGVSIEIVGTFIWLTGNT
                     KPYKDDIKALEFRYSPKKYAWYKAPSDYKKRSRKNYDMDTIRGMYGSQKVKEDKEEKK
                     YLQAN"
     gene            complement(1734..1925)
                     /locus_tag="ACF3UE_002662"
                     /pseudo
     CDS             complement(1734..1925)
                     /locus_tag="ACF3UE_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281642.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            1849..2121
                     /locus_tag="ACF3UE_002663"
     CDS             1849..2121
                     /locus_tag="ACF3UE_002663"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3635996.1"
                     /translation="MLNALELNRGFLFLWSFSLKIILARKNGTLLEALRAELPAFEQT
                     IVPEFKGAVRAVLKKIHRPSIGVKMGEIANYSSTSSPMGQLKKMFG"
     gene            2292..2870
                     /locus_tag="ACF3UE_002664"
     CDS             2292..2870
                     /locus_tag="ACF3UE_002664"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3635997.1"
                     /translation="MKTKDLIIEEFIKSFGENGFEGTSVDYLAKQVGIKKGSIYTHYS
                     GKNEIFTIACEKILDKCIVAIKQLLEVERDKPLDEQLFILLKTVCLESDFLTADEIAF
                     SKRVAILSSSELLSLVDKLLAKYDNFIDDTVSRIFIDCAKQKMLAEEEITSAISVYRM
                     LLENLYIDSLANQNCNEKLNHLWRYFWKGVCS"
     gene            2902..>3328
                     /locus_tag="ACF3UE_002665"
     CDS             2902..>3328
                     /locus_tag="ACF3UE_002665"
                     /inference="COORDINATES: protein motif:HMM:NF018410.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HFD3635998.1"
                     /translation="MEIIKYIGAAFSTWFIGFFPYFEIYIAIPAGFAAGLNWFDAFLW
                     ASLGNWMVIPFVDICYEWLMKFNFMKKIMEKSLNGKWENRIEKHGAWVILLLTPLAGV
                     WTIGVIAKALKFNRAKLWIYSATSVGITGLIITILIINGI"
BASE COUNT         1290 a          477 c          613 g          948 t
ORIGIN      
        1 agggcaacac caaaacaagc gcatgatatt gttgtcaaaa acttaccgac caatttagaa
       61 acccttcata aaacgggctt atttagcgat ataaggcttt acaatagaga aggagtgaaa
      121 ctctattcaa gcttagaaac gccttccatt agtgcgaaag agaccttaga aagagaatta
      181 aatcgtaaag tatcagggaa agaaattcaa ccgactttgg agagaataga gcaaaaaatg
      241 gttcaaaatc aacaccaaga aacccctgaa tttaaagcaa ttcaacaaaa attggaaagc
      301 ttgcagccac ctataccacc aatacccaaa acacctaaac ttccaggact ttaaacctta
      361 aaaaaggaaa agagtagtta ccaaaaaacg gtaactactc tttttttata aaaacctttc
      421 ctcatgtttg aaaagctgat cgagaaataa agcacacaac ggtattcttt cttttttcag
      481 ttggtacatt ttgcagtctg taacgtgtca tttactgttt gttaccttaa catatccagt
      541 cgaaaacaca agggtatata aacgagcaag ctcgcccttg tgttttcttt gtgtctatgt
      601 tgcgttctcg tcacagcaaa cgacacgaac acactggcga aaatgaacca actgaaaaaa
      661 gaaaggagca tacactgtaa tttatttcta gcttttaaaa catgaggaaa acagcttcac
      721 ttcctcaaac gcctaacaaa aatggttgtc aaaaaactaa aaatcaaaaa aaagaaaaga
      781 ggaaaagaaa atggaaaaaa caaaaaaatt acaattagaa gattttacag aaaatgagtt
      841 ttttggaaca caagaacagc aatatctaaa agctcaagta agagaagagc taaaagagca
      901 aggctttatc atagatagca gttttgaggg cgattttaaa acatggatag gtgtatacgc
      961 aagaccaaaa gataaaccga cctacttaga ccctcaaaac gataaagaag cagaagaaca
     1021 agagcaatat tctattaacg gctttaaaca agattttagc gaatggtttg agtgggaaat
     1081 aaaaaatttg aaaattaaag aaatgtaaaa aaaagccaaa aatcaaaaag aaaaggaatg
     1141 atgaaaatga aatacattaa aaacgttgaa acattagaag aattgaaaaa agcctacaaa
     1201 aagttagctt tgaaattgca ccccgattgt ggtggtagca atgaagaaat ggcgcaacta
     1261 aacaatgaat atgatgaatt gtttgtcaag ctaaaaaaca ctcataagaa caaagacggc
     1321 gaaacctata caaaagaaac gactgaaacg cccgaacaat ttaaggacat tataaatcaa
     1381 cttttcaatc tgaaaatgga cggtgtatca attgaaatcg tgggaacttt tatatggtta
     1441 acaggcaaca caaaacctta taaggacgac ataaaagccc tagaatttcg ttattcacca
     1501 aaaaaatacg catggtataa agcaccaagc gattataaaa aacgtagtcg aaaaaattat
     1561 gatatggaca caataagggg aatgtatgga agtcaaaagg tgaaggaaga taaagaagaa
     1621 aaaaaatact tacaagccaa ttaaggcttg taagtttgtc agaaaggaag ttttaaagtg
     1681 gatattaaaa taaaaaaaat aaagggtatt cggattttat ggtggaaaag ggcctataag
     1741 ttactctttt ccaatttctt aataagtgtg gaaaaatcta caccatagtt gcctgttttg
     1801 tctcggtctg ttatttgata cgaattgaaa ctatcgtata acatagcttt gctgaatgca
     1861 cttgaattaa atcgtggctt cctcttttta tggagctttt cattaaaaat tattttagct
     1921 cgtaaaaacg gaactctttt agaagctttg agagcggaac tacctgcatt tgaacaaacc
     1981 attgtccctg aatttaaagg ggctgttaga gctgttttga aaaagattca tcgtccttct
     2041 ataggggtta aaatgggtga aatagctaat tatagttcca catcaagtcc aatgggacaa
     2101 ctgaagaaaa tgtttgggta acgaaacaca cagaatgagc aattttaata ttaaaattga
     2161 agagttacca tctctagaga aaagtttccg ccaaagtatt gacacataca aatcaccact
     2221 attacttgac aaatggaatc acctagtata aaatactaac taccggtagt tagtattaag
     2281 gatggtgaat tatgaaaaca aaagatttaa ttattgaaga atttataaaa tcctttggtg
     2341 aaaatggatt tgaaggaact tctgttgact atctagcaaa gcaagttggc ataaagaaag
     2401 gttctattta tacccactat agtggaaaaa atgaaatatt tactattgcc tgtgaaaaaa
     2461 tactagataa atgtatcgtt gctataaaac aattgcttga agtagagagg gataaaccat
     2521 tagatgaaca actttttatt ttgcttaaaa ctgtctgtct agaaagtgat tttttaaccg
     2581 ctgatgagat agctttcagc aagcgcgttg caattttatc tagcagtgaa ttgttgtcgc
     2641 ttgtagataa attattagca aaatatgata attttattga cgacacagta tcacgaattt
     2701 ttattgattg tgctaaacaa aaaatgttgg cagaagaaga gataacgtct gccataagtg
     2761 tatatcgtat gttgttggaa aacttatata ttgattcatt agcaaatcaa aattgtaatg
     2821 aaaaattgaa tcatttatgg agatattttt ggaaaggtgt ttgcagttaa aaattaaata
     2881 aacttgattg gaggtttaat tttggaaatt attaagtata ttggagcagc attttcaact
     2941 tggttcatag gtttttttcc ttattttgaa atttatattg caatacctgc aggttttgca
     3001 gccgggctaa attggtttga cgctttttta tgggcttcac taggaaattg gatggttatt
     3061 ccgtttgtgg atatatgcta tgaatggtta atgaaattta atttcatgaa aaaaatcatg
     3121 gaaaaaagtc taaatggaaa atgggagaat cgcatagaaa agcatggtgc atgggttata
     3181 cttttgttaa ctcctttagc aggtgtttgg acaataggtg ttattgctaa agcactaaag
     3241 tttaatcgag caaaactttg gatatatagt gcaactagtg ttgggattac tggattaatt
     3301 attacgatat taattataaa tggaatta
//
LOCUS       DAXLPC010000146         3273 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.151, whole genome shotgun sequence.
ACCESSION   DAXLPC010000146 DAXLPC010000000
VERSION     DAXLPC010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3273
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.151"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            201..1097
                     /locus_tag="ACF3UE_002666"
     CDS             201..1097
                     /locus_tag="ACF3UE_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3635999.1"
                     /translation="MEINLFEAGNRIKQIREKHGYTMADLGKLVDANSPSTINNWEKG
                     NNLPNRKRLEKIALLGGTSVEWIKYGDFSDYVYRLTQNIEEKILKEYGETTLNNYREA
                     LLDELTIEKITYEEDTKILAAAEKINTQNIFQEVKYMYSPDEDYRNIEVKPDLGLTDD
                     NKNIKMIGQRIRKIRKKENITLEEFGKLFSPTADKAVISNWENGKNLPNSERIKKIAE
                     IGGVSELYLMTGVDSSVAESMYFLSEVALDALERLSIEEVNRIIESFAGYLNVISKID
                     DPDKREISLNAICQLSLLDKMG"
     gene            1146..1520
                     /locus_tag="ACF3UE_002667"
                     /pseudo
     CDS             1146..1520
                     /locus_tag="ACF3UE_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353455.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1776..2528
                     /locus_tag="ACF3UE_002668"
                     /pseudo
     CDS             1776..2528
                     /locus_tag="ACF3UE_002668"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            2542..>3273
                     /locus_tag="ACF3UE_002669"
     CDS             2542..>3273
                     /locus_tag="ACF3UE_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3636000.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDPKKVGRKIRSIRK
                     KLGLTMQEFGYEVSNSPRSTVSTWEHGGNLPNKAKLKKIADIANCSVEDLLFDEGFIS
                     EKSQVKLINELKEENSKLKEKIKYYE"
BASE COUNT         1298 a          462 c          588 g          925 t
ORIGIN      
        1 ggttgaattg atagatggac tcaaagaaga aaattcaaag ttaaaagaga agataaaata
       61 ctatgaatgt ttatttgatg gtatagagag tctgctgaac tcacgaaaaa atccctagtt
      121 tttatgaatg accgttttgt aaatctgatt gaaatagatt tatatgattt cggtatatga
      181 tatacattag gaggtgtcga atggaaataa atctttttga ggctggtaat cgaataaagc
      241 aaatacgaga aaaacatgga tatactatgg cagacttagg taaactggtt gatgccaata
      301 gtcctagcac aattaacaat tgggaaaagg gaaataactt acctaataga aagcgtcttg
      361 aaaaaattgc actattaggt ggtacttctg ttgaatggat aaagtatgga gatttttccg
      421 attatgttta tcgcttgaca caaaatatag aggaaaaaat tcttaaagag tacggagaga
      481 ctacactgaa caactaccgt gaagctcttc tagatgaact tacgattgaa aaaatcacat
      541 acgaagaaga tacaaagata ttagcagctg ccgaaaaaat caatacacaa aatatttttc
      601 aggaggtgaa gtacatgtat tctcctgatg aagattatcg aaatatagaa gtcaaaccag
      661 atttaggact gactgatgac aacaaaaata ttaaaatgat tggacaacgt ataaggaaaa
      721 taagaaaaaa agagaatatt acattagaag aattcggcaa actattctct cctacagctg
      781 ataaagctgt tataagcaac tgggaaaatg gtaaaaacct tcctaactca gaaagaatta
      841 aaaagattgc agaaattggc ggagtttctg aactttatct tatgacgggt gtcgattcaa
      901 gcgtagcaga atcaatgtat tttctatctg aagtagcatt ggatgctttg gaacgtctgt
      961 caattgagga agtcaataga ataattgaaa gcttcgccgg ttatcttaat gtgatttcaa
     1021 aaattgatga tccagataag cgagaaatat ctctcaatgc tatttgtcaa ctatcacttc
     1081 tcgataaaat gggttgattc acaaaaaata ttgaaagatt actttactca cgaggaggct
     1141 tagctatgaa acctaatcta tcgttaacta gtgaacgtat tagaaaaatt atcgaatcca
     1201 aaggtctgac attagaacga ttcggtgatt taattggcga cacaccaata agttctgtta
     1261 ataattggct tagaggcgtg tctttaccca ataaaaatag gcttttaaca attgcaaata
     1321 ttggaaacac tagtgtagac tggattaaat ggggaacttt ggaagaatac atagcttcat
     1381 accttataga ttcaggttat gagctatata ttaaagactt tccagagata ccttacaaag
     1441 tctttaaaga cattcaagaa aaatatagtg atacgttttc actagataaa gactatgagt
     1501 tattgaatcc tataataaaa tttactatag ggggcgttac tttgaataga ataaaatttt
     1561 atattgattc cagtaaaaag accattaaac aaattagtac agaaactggt attaactata
     1621 caactcttac gaactattac cgtggtgagc gaaatcctag aaatactgaa acatggaata
     1681 tccttgctga ttatttccat gttcctgtaa gttatttgat gggattagac gaaacaaatg
     1741 ttgaactcaa aaaccttaat attggaaaca acatcaaaaa tattagaaaa agtaaaaata
     1801 tgacacaaac tgattttgct gagttaatgg gtctatcacg atcatatata ggggatttag
     1861 aaaacaacag gagtaatccc agtataaaaa cactggaagc tattgcaaga gcattggacg
     1921 ttccgatagt agcattaatc aacgattctt ctactgataa tatagtagag ccgtatgaaa
     1981 gtttgacagc cgaaaatatc cttcttaaac aagaaaatga ggaattaaaa tatgaggtag
     2041 aaagcttacg aaaaagattg tatgaaatcc aacaagtagt aaatcaagga gctgaaaaaa
     2101 tgattcccaa tctaaaagac gtaagtaaaa gaatcaaata tatcagaaaa aaattaggta
     2161 tgactatgga gcaatttggt tctcatttaa gcaactcacc taaaagtaca attgctactt
     2221 gggaaagtgg tagaaatata ccttctcaga aaaagttaca gctgattgct atagtaggag
     2281 aaaccaccac tgactggatt aaatggggaa ctttagaaga gtatataact tcatacctta
     2341 tcggtatagg atatgagcta tatattaaag actttccaga gatacctcac aaagtcttta
     2401 aagacattca agaaaaatat agtgatacgt tttcgttaga taaagactat gaattattgg
     2461 attctataat aaaaaatata tttacaaaat attactcaaa agaatttgaa gtaacccaaa
     2521 ttccataaga gaggtgattg tatgaagcca aatccttcag aagcaggaaa acgaatcaaa
     2581 caattacgcc tttcatgtgg ttttactatg gaagaacttg gaaggaaaat agataattca
     2641 ccacgtgcga ccatatccaa ctgggaacgt gggaccaatt taccaaatcc acaaaagctg
     2701 aaattattat caactatcac taattcaaca attgactgga ttaaatgggg aactttagaa
     2761 gaatatataa cttcatacct tatcgatata gggtatgagc tatatattaa ggactttcca
     2821 gaaatacctc acaaagtctt taaagacatt caagaaagat atagtaatac gttttcgcta
     2881 aataaagact atgagttatt gaatcctata ataaaaaata tatttacaaa atattactca
     2941 aaagattttg aagattatcg agacatagaa gttaaaccag accctaaaaa ggtagggaga
     3001 aaaattcgtt ctattagaaa aaaattagga cttactatgc aggaatttgg gtacgaggtt
     3061 tctaattctc ctagaagcac tgtgtcaaca tgggaacatg gtggtaactt accgaacaaa
     3121 gccaaactaa aaaaaattgc agacattgcg aattgtagtg tagaagattt gctttttgat
     3181 gaaggcttta tttctgaaaa atcccaagtt aaattgataa atgaactcaa agaagaaaat
     3241 tcaaagctaa aagaaaaaat aaaatactat gaa
//
LOCUS       DAXLPC010000147         3167 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.152, whole genome shotgun sequence.
ACCESSION   DAXLPC010000147 DAXLPC010000000
VERSION     DAXLPC010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3167
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.152"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..144
                     /locus_tag="ACF3UE_002670"
     CDS             <1..144
                     /locus_tag="ACF3UE_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3636001.1"
                     /translation="QTPQNFNKKLQRETVTLDELKAIADVLGVKFVQAFILPDGNEIK
                     IGN"
     gene            160..1002
                     /locus_tag="ACF3UE_002671"
     CDS             160..1002
                     /locus_tag="ACF3UE_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636002.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1065..2867
                     /locus_tag="ACF3UE_002672"
     CDS             1065..2867
                     /locus_tag="ACF3UE_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HFD3636003.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
     gene            complement(2926..>3167)
                     /locus_tag="ACF3UE_002673"
     CDS             complement(2926..>3167)
                     /locus_tag="ACF3UE_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFD3636004.1"
                     /translation="PPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQNFNSRSV
                     KGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1137 a          439 c          640 g          951 t
ORIGIN      
        1 cagactccac agaatttcaa taagaaatta caacgagaaa cggtaacctt agatgagttg
       61 aaagcgattg ctgatgtgct aggtgtcaag tttgtgcagg cttttatatt gcctgatggc
      121 aatgaaataa agataggtaa ttaggaggtg taatttgtat tgaaaatcat aacaataaat
      181 gatgttgagt atgctgtatt tgctgctaat gaaggtactt ccaaaccaca acctcatatc
      241 atagaaacga aatctggtac tattccagaa ggaaaacaac tgagtttatt aaaagaatat
      301 cttaagcaga atgatatttc cccaataaaa ggagcaacaa catattggtg cattgacaag
      361 gttcttaagc ttgattcaag taaagaaaaa actataagtg aaacaatcca taaacaaaaa
      421 tacttatctt taactgaaga aaatattgag aaacagcata agtttgtagg tgcaagctct
      481 aattatggga aagaaggtct aataatacat gatgttttga atgcatttcc tcttcataat
      541 gatttaaata ctattgcgat gaagattgcg gtaattgatg taacaaattc aacacatctt
      601 tctcaatata agagcaggtt gtctctatat gatttggcta aagtaattct ggagattcca
      661 aattttgatg atcggttggc aaaaggagat cctcagttga taaatattat cgcaaggaac
      721 attggtgcag ttaatatgtt ctcatttgca tccaagtact gtacatatca taatgtggaa
      781 gtgtgtggga gagatgatta ctccatcttt gatggtatcg ttaaaaatac tcttccacac
      841 tatatccaag gactaactac gaataagatt gatacgtggc gaagaagttt tgattacgag
      901 gcatttaacg aatgtgttgg aaaactactt gatgaaaata atatacatat tccttttaga
      961 agaagaaagt tagatcactt cttgtggtat gcgaataggt agaatataag aaaaaggcat
     1021 cgtaaaagtg attctggata aaattaatgg gggaggaaat aatagtggga ttatttgatt
     1081 ttctaaagaa aaaacaagga aaggttagta aacacgttga ttatcaactg gcttctagtc
     1141 tatttcgtac tggtaaagtt tttgctgaaa aattggaagt ggacatatca aatgtagatg
     1201 agtttcgtaa aacttttatc gcttttgatg tggaaacaac tggcctaaat tcttcttcag
     1261 atagaattgt agagattggt gcggtgctat ttaaagaagg agttccaatt caatcattcg
     1321 gaactcttgt caatccaaaa gttagaattg cagcctcagc ttcggcaata aataatataa
     1381 ctaatgaaat gctaaactct gctccaaatg agcaggaagt ttacccccag ttggtagaat
     1441 ttttaggaga tgcactagat ggaaaaatca ctatgtgtgc acacaatgca agtttcgatt
     1501 ttggattttt aagtaacaca ttttctagac ttgggtatga tgctaaaatt aagtatgttg
     1561 atactctgag tctctctaga aaacatataa aaggcattgt aaatcataag caagagactg
     1621 tagcggaata tttcggatta ataaatgaca ctgcccatag agcggaatca gatgcagata
     1681 tatgcggaaa gattttttgg ggtgttttag atattattga ggagtcgttg gaagaacaaa
     1741 aaaagcaaat agaaaagatg actccagaca taaaagaact tgaagcttgt gcttttattc
     1801 aagatattat tgagaaaaaa ggatgcgaca ccagttggat caggtatcga aaaaacagta
     1861 ataattatgt cgatgtaact tgtctatata cattcttaaa gtttaagttt gctaagaagg
     1921 gaaattacat cattattaga aaagatgcta caaatggaat tgatttacct atagaacctt
     1981 gtactgtaag tgaaggcggt acaacaaatg tgcgagtcta ttttcgtagc ccctttgact
     2041 taacgcctct ttcaaattat attttcagtg cttatagcga ttgttataat tctatgaatg
     2101 aatatatgag tgttagtaat tacactaaaa aagaagcaga gcaaagcctt agtatgctga
     2161 aatctatttc aaaatcagcg atgaaagagt tattattcga tgcaaaaaat cgtggatatg
     2221 atgagactga agttaaccta aatattgaaa aagtgatatc tagagaagat gtaattatta
     2281 acgggttgca taatcgagtt tcattaaaca agatacgaaa tatagggaat tgggagaaag
     2341 gatttgatgc aggttatcca tattgggaac gtggagaaac tgctaggaaa aatggcaaag
     2401 tagatgaagc tattgcactt tttgataaag ctcgatataa cggctatgat gctcctgcgc
     2461 tatatgattc ttatgctaaa gcttatcgaa aaattaagga ttacgataat gaaattctca
     2521 ttcttgatga aggaattatg cgtaaaacac ggcacgatgt tggtacttta gaggctcgta
     2581 gggataaggc aattaagcta ttatttgcta aacaagaggc agagcggata gctaaggaaa
     2641 aatctgattt tctaaaagcg aacaaaaaag aggatgcgat tagtgagcct agcaagaagc
     2701 gtggaagaca gattattcaa atgactgatg atggaacaat aataaaagaa ttcgatacta
     2761 tagcttctgc tgtaaaagaa gttggcgtta actcaaaaag tattagggat gctgcaaatg
     2821 gagttcaaaa acatgctgga ggatactact ggaaatacaa agattagcag ataatctaag
     2881 ataacctagg atcttcttaa tagatacccg tggtgctagt taattttaat atcctaaaga
     2941 atatctcaaa gttccttcaa aacgtcgttg tgctcgactt aatagaacac tgtaagccag
     3001 taatatgctt tcaaatctac tctctagccc tttaacagaa cgtgagttga aattttgaca
     3061 acctaatttt tctaaggaag aaaaaacagt cccaactgtt tttctttgtt ttccaagtaa
     3121 gctgtggtct agtttttctg atttatccat gtttttacgt ggcggaa
//
LOCUS       DAXLPC010000148         3162 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.153, whole genome shotgun sequence.
ACCESSION   DAXLPC010000148 DAXLPC010000000
VERSION     DAXLPC010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.153"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(62..286)
                     /locus_tag="ACF3UE_002674"
                     /pseudo
     CDS             complement(62..286)
                     /locus_tag="ACF3UE_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(840..926)
                     /locus_tag="ACF3UE_002675"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="ACF3UE_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2092..3132
                     /locus_tag="ACF3UE_002676"
     CDS             2092..3132
                     /locus_tag="ACF3UE_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFD3636005.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
BASE COUNT         1168 a          445 c          458 g         1091 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtgata tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc tatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gcaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt ca
//
LOCUS       DAXLPC010000149         3075 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.154, whole genome shotgun sequence.
ACCESSION   DAXLPC010000149 DAXLPC010000000
VERSION     DAXLPC010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.154"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(65..1285)
                     /locus_tag="ACF3UE_002677"
     CDS             complement(65..1285)
                     /locus_tag="ACF3UE_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFD3636006.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1305..1916)
                     /locus_tag="ACF3UE_002678"
     CDS             complement(1305..1916)
                     /locus_tag="ACF3UE_002678"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFD3636007.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1959..2891)
                     /locus_tag="ACF3UE_002679"
     CDS             complement(1959..2891)
                     /locus_tag="ACF3UE_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFD3636008.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
BASE COUNT          860 a          630 c          528 g         1057 t
ORIGIN      
        1 agcttaaatc atagataccg taagggactt tattctttat ttaaaacttt gcaacagaac
       61 ctttttattt tacagaagca ctcgaaactg catctactgc agtttcatcg tgtgtgctgg
      121 cgctggttac tgcatctgtt tttccaccat gaacagatgc acttgaaacc gcatcttcat
      181 ttccaacaag ttgttgaccc gtttgttgta aataccactc aatgattggt ttgaaatcaa
      241 gaatgtattc attgattcca gcatactctc cattttcatc atgcattgct tggtaattat
      301 gcacaatata tttttctggc acttgttttg gtacatgaac acgtaccgca tctgttgctc
      361 cgcttcgcag ttgttgaatt acccactcta catttttata cgatttttct gggtgacagt
      421 tggctaatgg attccctacc tgaccgggca cacgagcagc taacatctct ttcgcttctt
      481 ggcgcaaatt ataatataaa aattggttat tattatctgc aaaagttaat tccatcggca
      541 tcgaatctaa aaagtaattg atttgatcca ctgtcaataa cccacgattt aatttgacgt
      601 aagtatttcc agaaacggca ccgactgctt cagaagcttt ttccaaccaa tgatcatctg
      661 acatatcaac atcgggtatt gtcgtagcaa ttgttcctgt cgcatgcaaa tcttctggtg
      721 gaagcttttt aggccctgct aaggtagaca cgactttaat gaattttaca aaacttgcta
      781 atgtactgcc taaaaagtca acagttcgtg gatcaatcaa gcgatcttct tggtcaaatg
      841 cttcttttgc ttttcccaat aaaaattcat ttccgggcat cactaatgca ttcacgcctg
      901 gtgcgtccaa aatttggcgc aagtgtaatt gcgcgcgtga agttccttga tcgtagtaag
      961 aagcacccac aaccattaca ggtttatttt caagtggatg gattttaaat gatagccatt
     1021 caagtgcact tttcaatcct gctggaaccg tatgattgtg ttctggcgta gcaataatta
     1081 ccccatcagc cattaagatt ttgcgattta gctgttgaat agcaggacta tttgtttgat
     1141 catcatcttg attgaacaga ggtaaatctt tgatttcaat gatttctaaa ttaaatagtt
     1201 catgatattg tttttggata aatgttaata atttacggtt atatgaaagt tcagctgctg
     1261 atccgacgat acctattaat ttcatctttg tttgctcccc tcgattaaat cgtttcccat
     1321 gaaaagcttt cggcttcacg tttatttgct tggtgcgcat gttgcaattg actagtgatt
     1381 gtgacaaaga gtaagaaatc tttgaatagt tcacgtaatt ttgcgacttg ttcttcatca
     1441 atgagtcgtc cttgctcatc aaaggcttgg agtgaatgac ccaataaaaa ttctgagctt
     1501 ggcataattc gtgcctttaa ctctggtgaa tccaatattt ggcgcaaatg tgcttgtgcg
     1561 cgtgaagaac ctaacgtgcc ataagacgct ccggtaatca tcactggttt atccacaaac
     1621 ggaaaaatac catatgaaag ccaatttaat gcgttaatca atgaagcagg aaccgcatgg
     1681 tcatactctg gtgtgctgat gattacgcca tctgcttgtt caatttttcc agcaatttct
     1741 ttaacaacat ttggtagttc tgtgttttca ggtttgttaa atagtggcag ctccttgatt
     1801 tcgacaattt cgatttctgc ctcatttaca aaataatttt tcataaactg taataattca
     1861 cggtttgttg accgcgttga atttgttcct actaatccaa taaatttcat cttcattctc
     1921 tttcctttct aacatcgatt tctgactgtt cgcacgtact aaattttttc aaatcctttt
     1981 gtatacaaga attgattctc ttttgttaca actgctccct cgatacccgg ctgttcttca
     2041 agcgctttca acacttctaa agaagatgct ccaaataaac gtgtagtcca gatttctcca
     2101 tctacagaag aatcagacaa aatcgtcagg cttgctacgt catttttaac tggaaagcca
     2161 gttttcggat caatgatgtg atgatacact gacgaaccat tttgtagata acgttcgtag
     2221 attccagagg taactaaaga ttggttgttt agtttaacca ccgcaagcga ctcttcacgt
     2281 gaacctttag gatttcgcaa accaatacgc caagcaccat ccgaacgtct tggtgattca
     2341 ccaaaaacaa cgatatttcc tcctaagtta actaaagcaa acgctgcatt tcgctctcgg
     2401 caatgtgtaa ttaatttatc tgcaatgtaa ccttttgcta acgcccccaa gtcaatcatc
     2461 attcctggtt tggttaaaaa aacggttttc attttttcat ctaattgaat ttggtgtgga
     2521 tccgttagca gaagtaactc agttatctct gcttttgttg gaaccaatgc atcttcaaat
     2581 ccaatgtgcc atttttgtac aaccggacca atagcaatat tcagataact atttcttgca
     2641 caactatgtg cttttcctaa tttgatgagc tcaaaaagtt caggatgtac aatcacagct
     2701 tgtcgtccag cagcttgatt gatggccatt aattcagaag ttgcatcatg tgcgctgaag
     2761 cgatgttcat aaacgtgcaa ccattcgcct aactctgcta gtaatcgact aggctcttca
     2821 tgcccaactt gtaatgtaat tgttgtcccc atcatttgcc agattttcgt ttcttcgatc
     2881 acctgattca ttttgtacct tctttacttg aactacggat tacatgagta attagttttt
     2941 atttttgtta ctgttttcac aaccagatga tacgcctgct agatttattt gtcaaccgat
     3001 tttatatatt tttttatata ataaggtaat tttaatataa aattttatat tgtaaaaaaa
     3061 caaataaggg aaaca
//
LOCUS       DAXLPC010000150         3070 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.155, whole genome shotgun sequence.
ACCESSION   DAXLPC010000150 DAXLPC010000000
VERSION     DAXLPC010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.155"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(334..696)
                     /locus_tag="ACF3UE_002680"
     CDS             complement(334..696)
                     /locus_tag="ACF3UE_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636009.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(770..1150)
                     /locus_tag="ACF3UE_002681"
     CDS             complement(770..1150)
                     /locus_tag="ACF3UE_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFD3636010.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1232..2407
                     /locus_tag="ACF3UE_002682"
     CDS             1232..2407
                     /locus_tag="ACF3UE_002682"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFD3636011.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2484..3068)
                     /locus_tag="ACF3UE_002683"
     CDS             complement(2484..3068)
                     /locus_tag="ACF3UE_002683"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFD3636012.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          958 a          587 c          504 g         1021 t
ORIGIN      
        1 aacgactcag ttatcttatc atgtcgttag taacatgtca ataactattt tttaaatttt
       61 ttagaaatgt gatataacat ccacttcaga atcaacgctg ttaaatttat catgtatttc
      121 ttccttggtc aactataaat taagcattac tttgtgaaat gatttttcga tcaattatta
      181 ttattcgtta tacaaccgtt ttcaacatat tttgaaaata aaatgcacta aaaaactatc
      241 tttagcagaa catttcattg tattttttgg accaaacaat aaaaaaagaa gtttgaaaaa
      301 aattcaaact tctttgttcg cttaatctgt attttagaag aaaggcactc cctctacttc
      361 gtaagttcca agaacagagc gcatttgacc tggttcttcc caaatatatc cttcgcctaa
      421 ttcttctctt tgattctttt gttcagtttc aaagacaaac aacggaacat tttcctcttt
      481 aatatgtgta tttgtcaatt ccatcaaact aatcttgcta acatcgatat gaactatttc
      541 ttttaagaaa ttaagtatat tcgctaaacc agtctttcct tcagaaagtt ccgctaacgc
      601 aaattccaac ttgtcatcaa ttgaatggac caaaaatttt ttagtaccat cctccaaatg
      661 caacataatt gtaccagcaa ctcttttgct tgccaaaatt tccacctcga tcaacttgtt
      721 ctatggctta cataaaaatt ctagcacatt ttcagaaaaa atacactttt tatttcttat
      781 tttctttccg ttctagttca gataatgctt cttctatcca aataggtaac tgctccgcaa
      841 tagtggtaaa tccgatctta cgatttttat tcgtgaaata cctttttctg cgatatggaa
      901 cagctggatt tgttttttct aacgttctta aagataaact gatttttttg gaatattcat
      961 caatgtcgat gatctgaact gttactggct gtccgacttt taacaatgaa tggatatttt
     1021 tcgtataacc ggattgtact tctgaaacat gaataagtcc ttgcgtctcg ttatcaagag
     1081 aaacgaatgc gccataaggc tgtatccctg tcacttttcc ttcaattatt tgtccaattt
     1141 tataagtcat ctacttccct ctcttcgcat ttatcattat actgtaaata gctcaaaaaa
     1201 agaagcgacg aaaatgactg gaggtcttaa gatgatcgaa tttgataaac agatttcaag
     1261 aaaagataca gaaagtgtaa aatgggacgc aattgctgag acatatcaaa tggatgactt
     1321 acttcctttg tgggtagcag atatggactt cttgtctccc ggtggggtag ctaaagcgtt
     1381 tagtgaatac atcaaacatg gaatctttgg ttatgccact ctgtctgata aactatatca
     1441 ggctatcatt cattgggaac gccaacacca tgctgtggag ttgacgaaag aaaatatcgt
     1501 ttttacaagt ggtgtgttaa ccagtttagc tgcagcagta caaactttta caaaaccagg
     1561 cgattctatt ttgattcatg acccagttta tcctccattt tcctctatta tagaaacaaa
     1621 tcaacgtcac atcgttcgaa gctctttgct agaaaaaaat aatcatttca tcatggactt
     1681 gtctgacatg gagaaaaaaa tcgaagaaaa caatgtaaaa gcaatgattt tatgcaatcc
     1741 tcacaatcct ggagggcgtg tttggagcaa agaagaattg aaacagttaa gcgaattgtg
     1801 tttaaaacat caagtgattc tgtttagtga cgagatccat caagatttaa ctttattcga
     1861 tcatacattt acttccatgc taacgattga tcctaattta gatgatctac tagttgcttt
     1921 tacttccgca accaagactt tcaatctagc tgcaatcaaa aattcaatgg tatttatcaa
     1981 aaatccagag atgaaagctg attttgaaaa acatttagtg atgaaccaac agcacgaaat
     2041 caacactttt ggactgattg gaacccaagc ggcttatgag acgggtggag aatggttaag
     2101 ccaactgatt ccttatctag aaaaaaatgt tcaaacagtt aatcagtttt ttgaacagta
     2161 tcttccgaaa gtgagaataa tgaaccctga aggaacttac ttaatgtggt tagattttac
     2221 cgcctatatt tcagacgacc aagaattgga gaacactctt gttcggaaag gaaaagtcgt
     2281 attaaatcct ggcatcacgt ttggtccttc cggtcatggg catatgcgct tgaatattgc
     2341 ttgtccagaa gaaactttac tggaaggact taatcgaatc aagtatgctt tagagacaat
     2401 cgattaaatc atttattcaa aataaaagga cgagacctta ctaggtttcg tcctttttca
     2461 taattactcc gtaccatacc aaactattct gaaatttcaa ttgtttcaat cactacatca
     2521 tgtacaggtc ggtcttgtgg accacgttgt acatttgcga tttcatctac tgtgtccatc
     2581 ccttctagta catgtccaaa gactgtatgt cggaaatcta gccaaggagt tccgccacct
     2641 ttatacgctt caatgatttc tgatgggaat ccagcacctt ctagttgtcc aagcatatta
     2701 gctggcacat ttgtgttatt tacaataaag aattggcttc cgtttgtgtt tggacctgaa
     2761 tttgccatag ataaagctcc gcgaaggttg aacagttcac gactgaattc atcttcaaaa
     2821 ctttcgccat aaatactttc gccacccatt cctgttccag ttggatcgcc gccttggatc
     2881 atgaaatcag gaataacgcg gtgaaaaatc acgccatcat aataaccttt tttggaaagt
     2941 tcaatgaaat tttgaaccgt cttcggtgct agttcaggga ataattgaac agtaatgtca
     3001 ccacggtttg ttttgataac agcttttggt cctttttcac tttttaaatc tagttgtggg
     3061 aatgccatat
//
LOCUS       DAXLPC010000151         3035 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.156, whole genome shotgun sequence.
ACCESSION   DAXLPC010000151 DAXLPC010000000
VERSION     DAXLPC010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.156"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..708)
                     /gene="wzy"
                     /locus_tag="ACF3UE_002684"
     CDS             complement(<1..708)
                     /gene="wzy"
                     /locus_tag="ACF3UE_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HFD3636013.1"
                     /translation="MKEKINILMFSLTLVAFTIFCAFSLNQNYWLNWLGILIYLYAIC
                     TWHWRKGDSIFSLYTIFFTLFLLFSYGQCIMWAFGIGTDRGIGTTVVAYGTGIIPSES
                     DMIMVKWYSCISMFVFHIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIV
                     VPIVFVSKLLEVRIALVHGYNALYYGDYATQSGYLQIILYLFFPALICLLIGSNFSKV
                     ITRFVFIIFALYSLLGIM"
     gene            complement(727..1806)
                     /locus_tag="ACF3UE_002685"
     CDS             complement(727..1806)
                     /locus_tag="ACF3UE_002685"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3636014.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     TIIIPNPIKENLPYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIY
                     GEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEAL
                     AIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQK
                     GIKLRKELTSKNISNIWYEYLNQFF"
     gene            complement(1820..2866)
                     /locus_tag="ACF3UE_002686"
     CDS             complement(1820..2866)
                     /locus_tag="ACF3UE_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3636015.1"
                     /translation="MSVKISVIVPCYNVEKYIDECINSLINQTLKDIEIILLNDGSTD
                     NTLAILKKYEKLDSRIKVYEHKNMGLGPTRNRGIKIANGEFLAFVDSDDFVSNTMFES
                     LYNCAIAENADIAIGEVGIFSDREIERVKIRKSLTNLKTIELATYNKKEFFKQFYFNR
                     LYSHNAWDKIYRRSLVLEFNLSFGDNKIIFAEDNWFQLQVFMTNTRICFVDKLCYYYR
                     QQNNSIMHKPKSNLVFRHGNMIADYEKLIRQNGNNIIDKKACMLVAFDVLIMEIFNQK
                     NVGGTCEDYKNALVSLKHHKILRENISNIVRMKAYELEPNMRKKLALVTISIMFNFKM
                     YKTAYNMLWRIYNR"
BASE COUNT         1010 a          559 c          311 g         1155 t
ORIGIN      
        1 cataattcct aataaagaat ataaagcaaa aataataaaa acaaatctcg ttattacttt
       61 tgaaaagttg ctaccaatta ataaacatat taaggctgga aaaaaaagat atagaataat
      121 ttgtaaatat ccactttgtg tagcataatc accataatat aatgcattat aaccatggac
      181 taatgctata cgtacctcta gtaatttaga aacaaaaact atcggtacta ctattataga
      241 aatgatacac cctattttaa ataaaaactt tctatcggca tcagcatctc cagattcata
      301 ccaactaact tttcttagtg tggtttttct cgtaaataag agtgctccta tgtgaaatac
      361 aaacatagaa atacaagaat accattttac cattatcata tctgattcac taggaataat
      421 ccccgtacca taagctacta ctgttgtacc gattccacga tctgttccaa taccgaatgc
      481 ccacataatg cattgcccat aactaaataa taaaaaaaga gtgaaaaaaa tcgtgtataa
      541 tgaaaatatt gaatctcctt ttctccaatg ccatgtacag attgcatata agtaaatcaa
      601 tattccaagc caatttagcc aatagttctg atttaatgaa aaagcgcaaa atattgtaaa
      661 cgcgactaac gttaacgaaa acatcaatat atttattttt tctttcacac aatatcctcc
      721 ttttggttaa aagaactggt ttaaatattc gtaccatata tttgaaatat ttttagatgt
      781 cagttctttt cttagtttaa ttcctttttg cgcttttctt accacacttt ctctatccaa
      841 aagtacccta cgcattgcat ctgttaactt atctagatta ttacattcaa caagatgacc
      901 tatttcattt ctatcaccta aatacattct tgcgccacct actggacaat ctgtagcgat
      961 aactggcact ccaatagcca gtgcttctaa catagaatta gatatacctt cataatcaga
     1021 agaaattaca aatcctgccg cattttgcat cttttcatgt attttatttg taaattcttt
     1081 tagatgaaca aattctgtta atccattatg gttgatataa ctttcaagct cggtttttaa
     1141 tcccccttct ccataaatat ccagttcaca ctcatatcct tcatgaataa gttttcctat
     1201 tgcatcaatc attaagggca aatttttttg tttatccaat ctacatgcag taataaattt
     1261 tttactactt gtagttttat tataataagg taaattttcc tttattgggt tgggaattat
     1321 aattgttttt acttttttat cattgatctt actaaaatat ttttttgcgt ctggtgtttg
     1381 aaaaacaatt ccatctacat ttttataaag aaaatctcta attttcctaa tccatggttc
     1441 ttctggattc cgttgtggat catttcgttc agaaacaatt aatttttgtt ttactcctaa
     1501 caatgaaata atgacatgga tatttacatc agcaaggaac gaaataacca gatcaggctg
     1561 tatttccctt atttttttcc taagttcctt aaagcgttcc aaaggtctaa atgcacgaaa
     1621 cgaactttta catattattg gatgtacctg tatttttcta ttcagttcat agtcttgccg
     1681 attcccatat atagttataa tatcaatttc ccagttatct tgaataaaat tatttgccaa
     1741 attcgcaatt actcgttctg cccctccttt tcccataatt cctatcacaa aggtcaattt
     1801 cctcatattt cctacctctt tatcgattat atattctcca gagcatatta tacgctgttt
     1861 tatacatttt aaaattaaac attatactaa tggtcacaag ggctaacttc tttctcatat
     1921 taggttcaag ttcatatgct ttcattctaa ctatatttga aatattttct ctcaatattt
     1981 tatgatgttt caaagaaact aatgcattct tataatcttc acatgttcca ccaacgtttt
     2041 tttgattaaa aatctccata attagtacat caaatgcaac caacatacaa gcttttttat
     2101 ctattatgtt gtttccattt tgccttatca acttttcata atcagcaatc atatttccat
     2161 gtctaaaaac caaattactt tttggcttat gcattataga attattttgt tggcgataat
     2221 aataacacaa tttatctacg aaacagattc ttgtatttgt cataaatact tgtaattgaa
     2281 accaattatc ttctgcaaaa attattttgt tatcaccaaa tgataaatta aactctaata
     2341 ctaaactacg tctatatatc ttatcccaag cattatgtga atataaacga ttgaaataga
     2401 attgcttaaa aaattctttc ttattatatg ttgctaattc aattgttttt aagttcgtta
     2461 gactttttct tatttttact ctttctattt ctctatcaga aaaaatgcct acttctccaa
     2521 ttgcaatgtc cgcattctct gcaattgcac aattatataa actttcaaac atagtattgg
     2581 aaacaaaatc atcagaatcc acaaaagcca aaaattctcc attagctatt ttaatccctc
     2641 gatttctagt tggccctaac cccatatttt tatgttcgta aacttttatt ctagaatcaa
     2701 gcttttcata tttctttaat atcgccaacg tattatctgt tgaaccatcg tttaacaaaa
     2761 taatctcaat atctttcaat gtttgattta tcaaactatt tatacactca tcaatatatt
     2821 tttcaacatt ataacaaggt acaattacac taatcttaac tgacattatt attacctctt
     2881 tatcaatttg ttataaatat aaattaaaaa tacccatttg tttttcaatg caaacttagc
     2941 actaattcct ttccaattat ctttatattt gcatttacaa atagctctag tatagtattc
     3001 gtcacttaga ttttgtataa tatctttttt tatat
//
LOCUS       DAXLPC010000152         2989 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.157, whole genome shotgun sequence.
ACCESSION   DAXLPC010000152 DAXLPC010000000
VERSION     DAXLPC010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.157"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(628..1380)
                     /locus_tag="ACF3UE_002687"
     CDS             complement(628..1380)
                     /locus_tag="ACF3UE_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFD3636016.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(1395..2642)
                     /locus_tag="ACF3UE_002688"
     CDS             complement(1395..2642)
                     /locus_tag="ACF3UE_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFD3636017.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(2718..2864)
                     /locus_tag="ACF3UE_002689"
     CDS             complement(2718..2864)
                     /locus_tag="ACF3UE_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HFD3636018.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
BASE COUNT         1037 a          483 c          366 g         1103 t
ORIGIN      
        1 agtttggaat ggacagaact ttttactaaa gcttcttgtg ctagttttta taattatatt
       61 aaatttttat cttttattaa agtcagataa aaattctttg gaaatgtaat ggtagagata
      121 tttttacaaa aggacttgca gcgctgtagt tggtgctgca ggaggaccta tttcggccgt
      181 tacaggaggt attggtaatg tacttgtcgg atgtgcatta aagcctgttc ctgcaagtta
      241 aatttataaa aacaggaaag taattatctc aaatcctatc aagtacaatc ataggattgc
      301 acttgacagg acaaattttt taactaaaaa atgaaaaaca ctttctaaaa attagtagaa
      361 tttgccaaat ctttcgcatc ttccaccata catttaattt taattcccct ttatggtact
      421 taataaaaac aagaaaagaa ctattcattt ggcccttttt tggttccaga ccatagaaat
      481 attcctccag taactaatat tgctgttatg cacgtaacta ataacagcta taaaaattgg
      541 tacaacttta ataggattca gaaaaatttg cactagtgaa ggaatctatt ttattagaaa
      601 aatgcaatct ccctaaagaa aaaaccacta aacagtgctt tctttcaact tctccttaat
      661 tttttgtgct ttccctaaag taaagtttct ggccaactct gaatcaaaat atagtgaacg
      721 ttttttaaaa tctatttctt taacgttaaa gatatttact aaacacgctc gactaattct
      781 tgttaacata ggatatttct tttcaagctc actaattctt ccataaaatt cgtactgccc
      841 atctttagta cacaatgata atctatgtgg taattttgaa gcttctacaa aataaatgtc
      901 atttatatca aaagtaaatg tttgagaacc tatggaaaaa acaaatgctt gattcgtaac
      961 ctgttttgtt gcatctatcc tttcttgcgc taataacaat aactcaacaa tctcgtttcg
     1021 atactcatct agtgtttgat cttttgttac aaatcctaac gtttcaactc ttctttttat
     1081 tgttacgggt aacatctcat catgagtagt tgtaaaaatg atttttgctt gaacatcata
     1141 ttttctgatt acttctgcta attctatacc gttaacttca tgatttaaat caatatctaa
     1201 gaaatatatt ccttgctttg gtcggaattg tttgaggtat tttttaactt ctaacggact
     1261 ttgtgttttc aatactatct taaatacttt atcgtgaaaa agaatgaaat tatcaataat
     1321 tcgttctaac tgatttaatt gtataatttg atcttcacat aatattattg gataactcat
     1381 aaatcctcct tccctcaaaa caacaaaata acttgagtag taaattgata cggatcgttt
     1441 tgatagttca caaacatatt gggattcttt ttattgattt cctctatact agataaacct
     1501 aacccttgat gtcccttttt tgttgttatt ccttttttca ttagagtatc tatagagagt
     1561 agtatctctc tacaactatt cgatatcgaa atttctatct gtttatcatc tcggtaaata
     1621 gctagagaca gttctctatc ttgactctct atagatgctt caattgcatt atcgagaata
     1681 attccaagca ccctaataca gtcaaatatt ggaacaggaa cttcaataat agtacttgga
     1741 cattcgaatt tacaacaaat cttattgtta tttgcttggt atagcttcgc tatcaacaaa
     1801 cttttcaaat attcattttt tatatttttt aaataacgat attcaaactt attggttaga
     1861 taagaattag aatagatctc taattctttt atttcttttt ccaatatcga atcatggttt
     1921 tgattagcga tttcttttaa actcagcaat aaatttttat agtcatgtct aaatctggca
     1981 aatttttctt gatctttttc cagtgaatca gtatattttt ttagataaac caattctttt
     2041 cttttcaatt gctgttcata ttgttctcgt tgcctaatag ttattctaat aaataaaaat
     2101 agaacaacaa acatttgaat gattaaaaat attaagacac caaacacaaa atgatcaaat
     2161 acttgatatt gatgagcaac ataagaaaca aataaaccaa ttgtaagtaa ataaatcatg
     2221 aatatagcag taagtttaga actggactgt tcaacaatcc tatttatagc taattttcta
     2281 tataaccaaa taaacatcag caaaaacaaa gaatcaagca ttatctggaa tactacataa
     2341 ccataccctt ttatcccttc aaatgaaaac atatacgtca taaccatgga agtaataata
     2401 gatctgaaat catcaataag catacataat agtaatttat ttaaaagcac tatattagtt
     2461 ttcttctttt cctttaatat aaaataactt ccgattatag gtatagctgc ggaaacatca
     2521 gtaaataatt caacaaaaaa agtgagtggt atcaataaac atacaaaaag atattttctt
     2581 ttgttaagat cagtattagt catataaaat aagagaaaaa agaaaaagtt tcccacgaac
     2641 attcttaata gataagcttt tgtatcgata gtaatcaaga gatcccctcc tgattttagg
     2701 atatcataaa aaaaatttta gttacacttt ttaaataatg aaaaaacaca ttccactaaa
     2761 tttgatgccg gttttccttg aggttttgtt ccagcacctc ctttaatttt tttaagctct
     2821 tgatctgaac attgtttagc atttagtcta tttttttctt ccattacgat tccccctaca
     2881 aactataaat acttttatgt cactgattca atatacctat ttttctaatc aaaaaatttt
     2941 gagacatatt taatattata agtatcatta aaattgagat ttatctcca
//
LOCUS       DAXLPC010000153         2906 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.158, whole genome shotgun sequence.
ACCESSION   DAXLPC010000153 DAXLPC010000000
VERSION     DAXLPC010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.158"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(81..209)
                     /locus_tag="ACF3UE_002690"
     CDS             complement(81..209)
                     /locus_tag="ACF3UE_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636019.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            complement(289..744)
                     /locus_tag="ACF3UE_002691"
     CDS             complement(289..744)
                     /locus_tag="ACF3UE_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFD3636020.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(882..2810)
                     /locus_tag="ACF3UE_002692"
     CDS             complement(882..2810)
                     /locus_tag="ACF3UE_002692"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFD3636021.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
BASE COUNT          936 a          570 c          525 g          875 t
ORIGIN      
        1 aattattcag gttacaaaac attgattaaa aaaagcccct gcatcgcagg agcatcccct
       61 atatcgtttt aataggtcaa tcaaaaagca gtatcaaaca cattttgtat caaatcagga
      121 aataatagat aagctaagcc cagaatcaaa agtaccgcta gaagaaacca gccgattgtt
      181 cctatgaaat actttaattt ttcgaacatt gtatcacctc gttgtcagta tatcacggat
      241 cagtaaattg ggggtgttaa gaatctccta aaatagacaa aatttgttct attttcctaa
      301 agcaaatact tgtaagatac agtaagtgat accagaagca atgaccggtc cggcggcgat
      361 tcctcttaag aagacaacac ctaaaatcgt gccgaaaaca agtgcaacag tgatttgtgg
      421 atcagaagca atcaatccta cacccttgga agataagaca gccactagcc caccgcaaaa
      481 aacagctacc cagccaatag gggatttaaa ggcttctaat agatcacgta gaccgatttc
      541 tcctgttgcg atagggatta gaatagccgc tgtgatgatc gtcaccccaa tattgattcc
      601 tttgccttga agccaaggga aaaaggaacg ggaggctggt atgagcttca taatcaaaac
      661 aaaagctgcc gctatcatca gactttgatt tttagctaaa attgctacaa gtaaaataat
      721 tcctaaaaaa agccaacttt ccatgaaata tattcctcac tttcttcgaa acaatcataa
      781 catgttttta gaaagttaca aaagtaggaa ttcatccttc aagacctatt cataagctgt
      841 ttttttcata aaataaacaa aatcataaaa aaacactttg cttatttgac agaagacagc
      901 cgcgctttgt atagtggaca agacttacat ttttttgaag aatcagaaag atcaggtaaa
      961 ggtcttagta aacgcaagcc attcagaata accaatattg tgcttccttc gtgtcctaca
     1021 actccaagag gtagatttaa aaattgcagg aagttagaag caatcaacaa gagaataaca
     1081 agaatcgaaa aaataatatt ttgtttgatg atccgccgca tttttaaaga tagccgatga
     1141 ctgtagacaa atttatttaa gtcgcttttc attaagacga tgtctgcgat atccatagcg
     1201 gcatctgtcc cttgccccat agcgacacct aaagaagcgg ctgctaaagc aggcgcatca
     1261 ttgactccat caccaaccat cgcatttact tggtaaagtt cattctcttt tttgactagt
     1321 tgtgtttttt cttccggagt acagcttgca tagtaatgtt caatccctac ttgttcagca
     1381 atggcctttg ctgtgccaga atggtcgccg gttatcatac ttgtatggat gttttgggat
     1441 ttaaagtagg aaattacttg ttgggtattt gcttttggaa tatctagcag acctaaaaca
     1501 gcaattaact gctgatcttt agaaagataa atcacggttt tgccttgatt ttccaaacgt
     1561 tcgatcattt ccgcaatctc tttgctgatt atcatcgtct caggatcata tgcgtgcttg
     1621 ccaactttcc attgcgcacc taaataggta gtttgtaatc caaaaccagt aatttcttct
     1681 attggtaagt attggatttc ttcaggtatt gtgcaatcga aatattgcaa aatcgcatga
     1741 gcaagtggat gcgtcgtttt ttgttccata gcaacaagaa gttgttgtgc caaatccttt
     1801 tcatcaaaga aaaagctgtc agttacaact ggttttcctt tagtgagcgt tcctgtttta
     1861 tcaaaggcaa tcgcttttaa ttcagaaagc ttttctaaat ggataccgcc tttgattaaa
     1921 atcccatttt ttgcagaatt tgaaagagca gctagagaag ctggtgtagc agatgcgaca
     1981 agcgcacaag gagaagccac aactaataat accattcctc gataaaagct ttcatcccaa
     2041 ctccaaccta ggaaaaagtg ggggagaagg atcattagag gaacagcaag caaaatcaat
     2101 tttacataat tattttcgat tcgttcgata aatgaagctg tttgagttgg cgtattctgc
     2161 gcttcttcta ctaattggat aatcttagca aagacagttt cggaactcgt ttttgttact
     2221 cgaatcgtga tgggatttcc ttgattcagc gttcctgcat acatctcatc gcctaaatat
     2281 ttttctacag gcacagattc accgcttaat gcagactcat cgatcgttgc ctgtgtgctt
     2341 tctaaaaagc catctatcgg aacagctgct cctttagcga caaataccaa gttatccacc
     2401 tttagttgag aaacatctac ttcttgcatt tgtccatttt cttttaataa ttgggctttt
     2461 tgtggttgaa gattcatcaa agcagtaatt tctttttgac ttttattagt tgtgtattcc
     2521 tctaatgcac cgcttaaaca aaagatgaat gtcaacattg ctccttcaaa gtaattaccg
     2581 atcaaacagg caccaatagc agctaaagcc atcaataaat ccacattcag tgtccgatca
     2641 ttccacaatt ctttcaagcc ttccgatgtt tgtttatatc caccgatgat aatggcactg
     2701 atataaaaaa gtggggtgat ggtaagagag aatcggtcga agataaaacc gaagatcata
     2761 aataaaaggc agccgattgt tgctgcaaaa gcttttttct gattagtcat cgttattaga
     2821 cctccttgtc aaaacaagga tagcataata aaaatgtaat tgataataat aacagctaaa
     2881 tgagaacgat aatggttatc atttgg
//
LOCUS       DAXLPC010000154         2804 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.159, whole genome shotgun sequence.
ACCESSION   DAXLPC010000154 DAXLPC010000000
VERSION     DAXLPC010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.159"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..693
                     /locus_tag="ACF3UE_002693"
     CDS             <1..693
                     /locus_tag="ACF3UE_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFD3636022.1"
                     /translation="TTLREMKVTKETLTTVLNEIFSTPTKEGIQFEIQGMKETREADY
                     YPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTIPLESYPTEQII
                     AEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTRRGKTDPLKIYY
                     EKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVIHVEEKERKLAY
                     QRHQQMNREMER"
     gene            696..1181
                     /gene="ssb"
                     /locus_tag="ACF3UE_002694"
                     /pseudo
     CDS             696..1181
                     /gene="ssb"
                     /locus_tag="ACF3UE_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            1226..1459
                     /locus_tag="ACF3UE_002695"
     CDS             1226..1459
                     /locus_tag="ACF3UE_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636023.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(1618..1740)
                     /locus_tag="ACF3UE_002696"
     CDS             complement(1618..1740)
                     /locus_tag="ACF3UE_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HFD3636024.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            1895..2154
                     /locus_tag="ACF3UE_002697"
                     /pseudo
     CDS             1895..2154
                     /locus_tag="ACF3UE_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328871.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2602..>2804
                     /locus_tag="ACF3UE_002698"
     CDS             2602..>2804
                     /locus_tag="ACF3UE_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFD3636025.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
BASE COUNT          973 a          510 c          568 g          753 t
ORIGIN      
        1 acgactttac gggaaatgaa agtaaccaaa gaaacattaa caacggttct aaacgaaatt
       61 ttttcaacgc cgacgaaaga aggcattcaa tttgagattc aaggaatgaa agaaacgaga
      121 gaagccgatt actatccagg atttagctta cgtgtgctgg cacatttgga aaacatgcgg
      181 ccagatttta aggtagatgt gactacaggt gactcgatct atcctgcaac gatcactcac
      241 agtcataaat tgatgtttga ggatcgaacg attcctttgg aatcctatcc tacagaacaa
      301 attattgctg aaaaattaag tgcaaccttt gattttttaa cagataattc gagaggaaaa
      361 gatttttatg atctctatac tattcctaaa atggagaaga tcgatgagaa gaccttgaaa
      421 gatagtgtga gaaatacatt tacacgtcga ggaaaaactg atccgttaaa gatatactat
      481 gaaaaggata tggatgtact gaaaaatagt cacgagctaa aagatacctg gaagaaatat
      541 caaaaaagca atccttatgc tgcgtcgatc acgtacgatg agacaatgga ttcgattagt
      601 aatttgatgg aaaaagtgat tcacgtcgaa gaaaaagagc gaaaactagc ttatcaaaga
      661 caccaacaga tgaatagaga aatggagaga taaagatgat taataatgtg acattagtag
      721 gacgcttaac caaagatcct gatttacgtt ataccgcaag tggtactgca gtagcgactt
      781 ttaccctagc cgtcaaccga aatttcacga atcaaaacgg caattgagaa gccgatttta
      841 ttaactgcgt gatttggcgc aaaccagcag aaacaatggc gacattagct aaaaaaggta
      901 gcttgattgg tgtagttggg cggattcaaa cgcggactta cgacaaccag caaggacaac
      961 gtgtatatgt gactgaagtt gtagcagata actttcaact attagaaagt aaagcagcga
     1021 cagagagccg tgcgcacgct gatcaatcgt ccaccagtcc aagcaccgcc acctttgaac
     1081 aacggaatac agcgacgcct aacaacaatg gattgaacgc ttcacagaat ccatttggtg
     1141 gacaatcaat cgatattagc gatgatgatc taccgtttta gtttgagaaa gaaggagtaa
     1201 gcatggcaaa aaaattagtc tgacgatgga tctattgata cccgtaattg catttataga
     1261 cgggatttct ttgggcgtca ctgaaaatcc tttggtaaat agaattgcga aaggatcact
     1321 atttcttgta ttcgtgtatc ttgtctgttc ttatctttta aaaagagcag gaaaggataa
     1381 ttccttttgg cgattgacta aagtcacagt agcagcgaca gctgttatac ttacggctat
     1441 tctaccgctt tatatgtaga gttaacggga aatcgttgaa cttcttgcga aatattgcta
     1501 taatgaacat gaaaaagagg agttgcgcta acaacccctc attaacagca ccgattaaag
     1561 aacggtggca gaatattagt tatttggaaa taaccgctga cctgctaaag tagacggtta
     1621 tttctttttg tcatttttaa gcatatttac aatcaaacta atcaaagcaa tggtaaacat
     1681 accaaaacca agaatggttt gaattgtctc atatgcggac aaaaggctta ctcctttcat
     1741 agattttagc acttacattc ataagcacca ccacctttcc agaagtcgcc accgtcttca
     1801 aactttactg tcttgactat tatagcatat ctaaaatcga ataaaaattc tcaattttag
     1861 ctgtttttgc tataatttta gcgaggtgat cgtgatggaa caatatattg gtttactcga
     1921 taaattaggg tgatcaagac acagccattg cttgtgcgat ttacattacg cacgagtcat
     1981 gaaccaatca attgtgtagt ggccaatata gaaatagcgg ataaattgct gattttggaa
     2041 gaaggcaagt atactatttc agtgacaggt cacttcaata aacgaaatca actagtcatt
     2101 gaatcaatgc aaattagaaa ccctgatcat tttacgagat taatgggcat ataaataaaa
     2161 gaagagctgc agtcctaaat gaggattgca gctctttttg ttttacatag aaacaagaaa
     2221 aatgaaaagg cctttttagg aaggcgcaag cgccttctca attgaaaaac ctctctctca
     2281 ctccaaccgc caccgccgtt cgagaagaaa ggaagtgaac gttgcacgtt cactaagata
     2341 aggggtcttg caaagcaaga caaaatagaa aaaacttcct ctcaccaaaa ggttcgttcc
     2401 tgttcgctat ctctttattg atttgccaga ccggcaacaa gttgcctttt atcaccaaaa
     2461 agcgacaagg acaagggtaa atggcacgct gcacgccctt gtccttgtcg cttttagttg
     2521 attcattctg gccaacaaat caataaagaa agaactaacg aaaggaagta aaacctttcc
     2581 taagaggagg cagaatcaat catgcgaaag aaatttgatt attggggtgt tcccttcagc
     2641 gaattattcc caaactatca tgcaccatat actgtcgaat gcgattgtgg agaaagagcg
     2701 aaatgtatca aaagctattg tttgtatcaa tgtccaacat gcgggaaaaa atataccttg
     2761 tcttatggcg attatatttt gattgatgag aaaggaaaga aacg
//
LOCUS       DAXLPC010000155         2692 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.160, whole genome shotgun sequence.
ACCESSION   DAXLPC010000155 DAXLPC010000000
VERSION     DAXLPC010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2692
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.160"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..678
                     /locus_tag="ACF3UE_002699"
     CDS             <1..678
                     /locus_tag="ACF3UE_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636026.1"
                     /translation="VVYGVAYYLLSEPKQIAASNIFTAVMTLMCVMCFSIFSYLLVQF
                     IRQNLTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIKNFLTTIDQFINGYMYL
                     FEVGFILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVDFGKYEELIHTDIVHTS
                     IHEVTVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGIGKLRLDGSNIQQNKPY
                     VLGKVVI"
     gene            722..991
                     /locus_tag="ACF3UE_002700"
     CDS             722..991
                     /locus_tag="ACF3UE_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636027.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            1223..1519
                     /locus_tag="ACF3UE_002701"
     CDS             1223..1519
                     /locus_tag="ACF3UE_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636028.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            1521..1943
                     /locus_tag="ACF3UE_002702"
     CDS             1521..1943
                     /locus_tag="ACF3UE_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636029.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            1962..>2692
                     /gene="mobL"
                     /locus_tag="ACF3UE_002703"
     CDS             1962..>2692
                     /gene="mobL"
                     /locus_tag="ACF3UE_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase MobL"
                     /protein_id="HFD3636030.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNT"
BASE COUNT         1032 a          377 c          522 g          761 t
ORIGIN      
        1 gtggtctatg gggtggccta ttacttgtta agtgagccaa aacagatcgc ggcgtcaaat
       61 attttcacgg cagtaatgac attaatgtgt gtcatgtgct tttctatttt tagttactta
      121 ctcgtccaat ttatcaggca aaatttaaca atgagtaaac ttttcaaaag tttattggac
      181 ttacttatct taggcagtat gttaacgact ctaacagatc ggttcgaaca atctgaaaaa
      241 acggtagagg ggataaagaa cttcttaacg acgattgatc aatttataaa tggatatatg
      301 tatttgtttg aagtaggctt tattctcact ttgtttggtt gtgtatttat aaaactcatt
      361 aaaagatcaa tcgaaaaaga aatggttatt gatctaattc cgacgctgag cggctatgag
      421 tattacgttg attttggaaa gtatgaggag ttgatccata cggatatcgt tcacacgagt
      481 atccatgaag taaccgttaa gggcatcaga tctactttaa aagatggaca ggagacgaaa
      541 acaatcgacc gaagaaaaga ggtctacaat ttttataaag ttgaagcaag tctacgatat
      601 ggcattggga aattgaggtt agatgggagt aatattcaac aaaacaaacc atatgtttta
      661 ggaaaagtgg tgatttagaa cttcctatga aagatgaata aataaggaga atcttttgaa
      721 aatgattctt ctttacagaa ttgtgcttat agttggcacg gagttaaaaa tcttaaagaa
      781 ggagcagtta ttcaaagtga aagaacatca taatcagtta ctatgtatta aaacgggtac
      841 gatgaacatt caataccgaa cagaatattt agaattaacg aatcaaactg attttttgtc
      901 gattcgagag caacataagc aagaaaaatt aatggctact tatagccaat tgattgatga
      961 gtgggaacaa ttcaaggaat ctaaaacata aaattccatt taaacacctt attttttaaa
     1021 gagcataagg aaacgtgacc ccacttttaa aaaaagtggt tggataggct gtgcctatca
     1081 cgtttctgaa aaaaataaat gaccccaaaa taccaatata taggatagta caaggatagc
     1141 aaaggatagt aaaaggatag aggtaggata gcgaaaagga taggatcctt ttcactatcc
     1201 tatattatat tggaggatat ttatgaatgt taaaattaga gatttagatc caaaattcat
     1261 ttctgaaatt gatcgaagat gcgttgaact aagtaatcgt acaggaaata aatggagtcg
     1321 taatgattat ttaaagctac tcgttgaaaa tgattttgat cgtcctttga tggaatacaa
     1381 acaagaaaag tttgaccagt tattagaaaa gttttcagaa attcaaagtt ataacacaaa
     1441 gatattagaa gaatatgtta gccaaaataa tcgtattata gaaatcttga ttgagcaaaa
     1501 tagaggaagt gaactttgat atggcaaagg ttatagacaa acacatttac tttcaccaaa
     1561 cacatatcga tgtattggat gaaactattt ctactcatgc agaggttaaa aactatagtg
     1621 aagctgttcg ctttttatgt atgaactatg atccagaagt ggagaaaaaa gtaaattcca
     1681 atcaagcaaa gttgaatgga atgagtaaag aaatttctat tttaaccgaa atggtttcag
     1741 aatttgcgga tcttcatttg aaagatacag gaatattaat tggtaaaaat tcaactgttt
     1801 atcaagaagc aaaagaacga gtggaaggaa aaattaaatc caatcaaaca aaaaaatatt
     1861 cccctcagtt gaagaaacct gtgaatgaat ctgttcatgc cagagtagat ccatttgatc
     1921 caacgaagat tctaaaaaga taaaaatgaa ggaggataat aatgactcaa tcgccttcag
     1981 ttattctcac ttgtcaattt actttgccga ataaaaagtc attttctact tatattgact
     2041 atattacaag ggaacaggct cttgaagaaa aggaacgacg tacgcccgaa gaagaacagg
     2101 aacttcaacg aatcaagaat gctttagagg agttttatat tcctgaagga gaaacttttt
     2161 cggagagtaa gacgggtaaa gaattcagtg aaacgtcgaa tgaagctcaa tcgttgatgg
     2221 aacatggaat caattttgac aagttagagg aacaagattt taccaattat ctttcttata
     2281 tgacacgtca ctatgcgtta gaacaaaaga aagaactgac gcaaagtgaa caaaaagaat
     2341 accaacgctt gaaccaagca atgaaaaaat atcaaacaga accccataaa aaagcttcag
     2401 gaaatcttcc tggagttttt tctatagctt cagacgaagt gaaaggaagt gatctgaagg
     2461 agattaagca aatcttccaa agaggacaac aaaaaggctc aatcatttat caagatgttg
     2521 tttctcatga taattcgtat cttgaaaaaa taggattgta cgatcccaaa acagatactt
     2581 tagatgaaga agggttaaaa gcagctggaa gaaaaatgat ggagacatta ttcgagaaag
     2641 aacaattgaa tgaaacaggt tactggatgg caacgattca ccgtaacact aa
//
LOCUS       DAXLPC010000156         2663 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.161, whole genome shotgun sequence.
ACCESSION   DAXLPC010000156 DAXLPC010000000
VERSION     DAXLPC010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2663
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.161"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            2..793
                     /locus_tag="ACF3UE_002704"
     CDS             2..793
                     /locus_tag="ACF3UE_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFD3636031.1"
                     /translation="MPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFDGFSP
                     FPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYFGSIL
                     GINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISFVLSM
                     IGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILLQLSF
                     IGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            863..1603
                     /locus_tag="ACF3UE_002705"
     CDS             863..1603
                     /locus_tag="ACF3UE_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFD3636032.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            1614..2618
                     /locus_tag="ACF3UE_002706"
     CDS             1614..2618
                     /locus_tag="ACF3UE_002706"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFD3636033.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
BASE COUNT          839 a          438 c          544 g          842 t
ORIGIN      
        1 aatacctatt tctgaatatc ggaaaaaagc acgagtttct ttggaaaatc aatggggaat
       61 caatacttgg cttgttttct tatctataat atttacgagc gtcatccaga acttttttga
      121 cggtttcagt ccttttccgg aagaaagcat gcagcagcac ttattgagtt ttctagtcga
      181 taatttactt ttattcgcat tcaactatgc attgttttac attgcgctag tagttgtacg
      241 gggtggcaga ccaaaaagta accttttatt ttcagttttc caaagaaagt attttggttc
      301 gatacttggc atcaatttga tcaattcagt catcaactgg ctactcaaca gtttaatctt
      361 tctgcccatg tttttaatca gcggagtgag tacttatatg cagctgcttt tcagttcaaa
      421 tgcggtacct acgggtgtca tgccagaaga ttttcttgat atcagctttg ttttatcgat
      481 gatagggatg atttttgttt cagcactcat catgagtatt gttggcggtt tattccaatt
      541 tgctgcatgg acaaagttcg actatcctga tttgtcggtt attcaatgtt tgaaatatgg
      601 ctggttttta ttgaaagata gaattggtac gtatattttg ttgcagctgt cttttatcgg
      661 ctggtatttg ctaggagcaa tcgctttgtt catcggtctt ttgtgggtca ttgtttatgt
      721 gaatgtgtca gttgcagaat tttatgaaca agcacggatt gaaaaaggag gtccagacgc
      781 ctattttact tagcatgtaa gcagtttatt catcaaaaaa ataacttttg tggtaggata
      841 aatctttgag ggggaatgta cgatgaaatt aactgtttta ggatgcttag gagcgtatcc
      901 ttataaaaat caagggacaa caggttattt gcttcaatct gacgggttca atttgttgat
      961 cgatgcaggt agtgctacgc tgatcaaatt acaagaacac cttgatccac ttgatctaga
     1021 tgctgtgatc cttagccatt atcatcatga tcatattgct gaccttggtg tattacagta
     1081 ttactggcaa cttcatccta agagaaatcc ggagacattg ctttcaattt atggacacac
     1141 aaaagattcc attcactttg aagaattgac gttggaaaat gtctcaaaag gacatcctta
     1201 ttttgaagct gaagaattaa aaattggtcc ttttctgatt acttttatgg aaacaatcca
     1261 tccagtagta tgttacgcca tgcgtatcgt agaagaaaca acggggaaag tattcgtatt
     1321 tacaggtgat tcaggttatt tggaaagttt cgctgatttt gcgaaagatg ctgatttgtt
     1381 tctagcagat acctatcttt ttgaaggaaa tgaacatcat catgcccatt tcacttcaaa
     1441 agaagctgga gaacttgcga aatcagctaa cgtaaagaaa cttgtactta cacacctacc
     1501 tcagtttggt gatttagaac aattgaaaaa tgaagcgcaa aaggcagcag gcaaagggat
     1561 tgatatagaa cttgctgcag ttgacaaagt gtttaacatt taggaggaag aacatgattt
     1621 ttgtaccaaa tgaaaaccac gacccaagaa tcaatttagc aattgaacaa tatttgctgc
     1681 aagaaatgcc tttagatgaa cctattttgc tcttttatat caatgaacct tcaatcatca
     1741 tcggcagaaa ccaaaatacg cttgaagaaa tcaatcgaga ttatgtggaa gaaaatggca
     1801 ttcatgttgt ccgtcgctta agtggaggcg gagctgtcta ccatgatttt ggaaacctga
     1861 actttagttt tatcatgcct gatgatgggg attcattccg tgactttgcg aaagtaacac
     1921 agccaatcat ccaagcactt catgaattgg gtgttgctgg ggcggaattg aaaggccgaa
     1981 atgatctagt cattgatggc atgaaatttt ctggcaacgc gatgtatgct accaacggtc
     2041 ggatgtttgc tcatggaaca attatgttcg actctgatat caatgaagta gtcaatgcat
     2101 taaaagtaaa aaaagacaaa atcgaatcaa aaggaatcaa atcgatccgt tctcgtgtaa
     2161 cgaatatcaa accatttctt ccagaagaaa agcaaaaaat gacaacagaa gaatttcgtc
     2221 aagaaatctt gttgaaaatt ttcggcgtag agtcagtaga agaagtaaaa acgtacgaat
     2281 tgactgatga agattggaaa aaaatcaatc gaatctctga ggaatattat cgaaattggg
     2341 attggaatta cgggaagtct ccagatttca atttctctcg ccaaaaacgt ttttctatcg
     2401 gttcgattga agtccatttg aatgtctcag aaggaatgat caaagaagca aaaatctttg
     2461 gcgatttctt cggactagga gatatctctg acgtggaaaa aaaattggtt ggacagaaat
     2521 atgataaagc atctctatca aaaatagtca gccaaattga tgtgaagaaa tattttggtg
     2581 cgatagaacc agaagaattg cttaccttac tttattgaaa ataaaaaata gcggaatcca
     2641 catatatgga ttccgctatt ttt
//
LOCUS       DAXLPC010000157         2620 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.162, whole genome shotgun sequence.
ACCESSION   DAXLPC010000157 DAXLPC010000000
VERSION     DAXLPC010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.162"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            67..504
                     /locus_tag="ACF3UE_002707"
     CDS             67..504
                     /locus_tag="ACF3UE_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636034.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGQWFFQALLCLEAGVKPNTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYLENVNKYGACYIMKKEDNENE"
     gene            497..1192
                     /locus_tag="ACF3UE_002708"
     CDS             497..1192
                     /locus_tag="ACF3UE_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636035.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEELNSKDATVDDYYLVFTKFLTCGTE
                     SIVLMGMDYELAVPEVFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRK
                     RMPYQRFERKKGQ"
     gene            1357..1557
                     /locus_tag="ACF3UE_002709"
     CDS             1357..1557
                     /locus_tag="ACF3UE_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636036.1"
                     /translation="MNKIIPLLLVLFVGEILMRLSAAVHLNLAVFLVILMFCLIFWRF
                     VLALVSLLFKMIAAIFFIGLFR"
     gene            1573..1752
                     /locus_tag="ACF3UE_002710"
                     /pseudo
     CDS             1573..1752
                     /locus_tag="ACF3UE_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1814..1998
                     /locus_tag="ACF3UE_002711"
                     /pseudo
     CDS             1814..1998
                     /locus_tag="ACF3UE_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            2032..2463
                     /locus_tag="ACF3UE_002712"
     CDS             2032..2463
                     /locus_tag="ACF3UE_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFD3636037.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
BASE COUNT          948 a          406 c          538 g          728 t
ORIGIN      
        1 aacatggaaa cttatgaaaa cgaatattgg ttaaccaaat tagagaacta aaaaggagaa
       61 aaaaatatgg ctcaaaatta ctatgacgaa tttgtcaaat tacctttgga taaaatggca
      121 caaaaaatgg aggatatgac attcctatac aatgagacac gtgttccaaa aaaacattat
      181 aaggaaagat tgtcggtagc tgtggaagaa atgattgaat cgggtgtcga aatgaatctc
      241 attgcgacct actatcgaac gcttgaagaa ctgaaaaagc aaaatggaca atggtttttc
      301 caagccttac tatgcttgga agcaggcgtc aagccaaaca ctatcaaacc ttctgaatac
      361 caagctttag aactaacgta tgggaaattt gtcgaaacga aaaaagccaa gactgtttca
      421 agtgaatggt tggactactt agaaaatgtc aacaagtatg gcgcatgtta catcatgaaa
      481 aaggaggaca acgaaaatga ataaggtgat ttatcaacta acaacggaag atgtgtcaca
      541 ctttttaaca aacaaagaac atttgaatga agtaatcaga cggattcaaa aagactttag
      601 ttgtatggaa gaaatgaagt actttattca aagagtcgaa gaacaattgt atttggaaag
      661 tgaaacgagt caaacgaagg ttacagtcag caataattat ttagacgtgt ataaacgtcg
      721 tcctgacaca ttaaaaaaag gagcggagct tctacgacta gaaacagaaa aatatatcat
      781 gaatgtttac ctagaaagga gtgaactggt cgaaaacttt gtcagctaca cgatttgcag
      841 gaaacactat tactcagaat cagaatatta ttcaattttt gagagcatgg aattaatgga
      901 agagctaaac agcaaagatg cgacggtaga cgattattac cttgtattta ctaaattttt
      961 gacgtgtggg acggaatcta tcgtgttaat gggaatggat tatgaactcg ctgtacccga
     1021 agtatttttg agggaatatg tagaagaagt agataaccca ggcgacgact ggtacacgac
     1081 tttaactgat tttttagata cctacactta cgacgataca gaagaaatcc aaaatgaact
     1141 tgaccgtaaa cgaatgccat atcaacgatt tgaaaggaaa aaaggtcaat aaccatttat
     1201 accgaaaagt gagaatgtgt gaaataaaaa caaaaaacct tgaaattaag ggaatggttc
     1261 ttatttcgca ccaatcgctc caaccgcccc cgccgcttag gtggtgcgaa ataagcgagc
     1321 aaagcccgaa aacctaagag aaagaaggag atttatatga acaaaattat tcccttatta
     1381 ttagtcctat ttgttggaga aatacttatg cgacttagtg cagctgtaca tttaaacctc
     1441 gcagtatttt tggtaatact aatgttttgt ttgatctttt ggcgatttgt attagccctc
     1501 gtaagtctac tattcaagat gattgcagcc atatttttca taggattatt tcgatgaaag
     1561 gagagagtac caatgccaat tgcaatagga aataaacggt tacccgtgac gttggatgaa
     1621 aagagacaaa aagaattgca gtaaccaaag cagaagtacg gcaaaagtga atccaggatt
     1681 atgtgtattg cgttagattt attgattgcg caagaaaaag caggatttga cataccagca
     1741 ctcaaaaagt gatcgcactt tgcgcacgtg ttaatacgtg ttataattat tttgtaagga
     1801 ggtatagtgc acaatgccac ttacgggaaa agaaatgctt aagttattga aaaaaatggc
     1861 tgggttgagc gaaggcaaga gggatttcat catcatcttt ataaggatgg tgttagaatc
     1921 actgttcctg ttcatgccaa tcaagatctt ggccgaggac ttgagcgaaa aattttaaag
     1981 gatgcgggat tgaaataatc tcgcattcga ttaaagaaag gattgactga aatgttaagt
     2041 gagcctttag caaaaaccta tcctgctatt tttagcccag aagaaggtgg tgggtacttt
     2101 attgaatttc ctgatgttca aggtgcttac acaggaatta acgaagacga tatatcttat
     2161 ggaattgcta tggcacaaga ggtgttaggt atggttttag cagattatat tgagcatgaa
     2221 gatctacttc cagaaccaac accaatcaat aagatttctg ttgaagatga ttcttttact
     2281 actttaattc gtgtagatgt tgccaaatat ttgaaagaca cagaacttgt caaaaaaacc
     2341 ttaacaattc ctcaatgggc ggataagcta ggcaaaaggg ctggcataaa tttttcagtc
     2401 cttctaacag aatcaattgc agataaagca gataacattc ttcgttctgg aagaaataat
     2461 tagaactcaa aagggtcaga aacttaaaaa tctttggctt ctttttttac tacaaagatg
     2521 gcttctttaa attatttgcc tgattgattt aaaaaaattg cgcaaagact acgagctaat
     2581 taagttgctc gtggtctttt tttatgaaaa ctttttagat
//
LOCUS       DAXLPC010000158         2600 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.164, whole genome shotgun sequence.
ACCESSION   DAXLPC010000158 DAXLPC010000000
VERSION     DAXLPC010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.164"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            30..1154
                     /locus_tag="ACF3UE_002713"
                     /pseudo
     CDS             30..1154
                     /locus_tag="ACF3UE_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1574..2218
                     /locus_tag="ACF3UE_002714"
     CDS             1574..2218
                     /locus_tag="ACF3UE_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3636038.1"
                     /translation="MYKTANELFNRLKSEKKELILNYILEEFGRVGYESASVRKIADK
                     ADLSAGSLYQYFNNKEGMLRVAIEHVFVILDEYINNINNAPLKLENRLEVMFETILEL
                     GRKHPELIVFYNKIPGDEQMTSEWVKQFYNNTSFFKVYWHTVNELQDEKEISDKIDPV
                     VYTFIIDTMMLSGELLQNTQYQEIKAKIFLEDSIKSSLILKENVIETLTVLARG"
     gene            2225..>2600
                     /locus_tag="ACF3UE_002715"
     CDS             2225..>2600
                     /locus_tag="ACF3UE_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3636039.1"
                     /translation="MTISNKNSMREEIIIIAIKHFSKFGYEKTRLLDIANEAKTSTTT
                     VYSFFKTKHDLYEAAVEYDLNIINLELEKIVKESSTLDEYIINIVERVRLNSEKKQLF
                     LNFFMLISTNSGQIKKIDIIEEF"
BASE COUNT          986 a          360 c          487 g          767 t
ORIGIN      
        1 tataagaaaa cacactggag gaattgttaa tgtcagaaag aaaaccacgt cgaacgttta
       61 ctaaagagtt taaaaatcaa atggttcagt tatatgcgtc agggaaaaag agaaccgata
      121 ttatcagaga gtatgattta accccgtcta cttttgataa atgggtgaaa caagcaaata
      181 cctctggctc atttaaagaa aaagataact taacacctga acaaaaagag ttaattcaat
      241 tgcgaaagca aaataaacaa ctcttgatag aaaatgatat tttaaagcaa gcggcgctga
      301 tattcggacg aaaagacaag taattgatgc aaataagcac aaatactcga tatcagccat
      361 gtgtaaagta ctgggtattg caagagccac ctattattat cgagaaaaag aaacgactca
      421 aggcgcagta gaagcaaaat tagaagaagc ggtggaagaa gtttttcaac aaaatagacg
      481 agcatatggt tcacgcagaa tcaagaaacg ccttgataag aaaaatctca ttttgagtcg
      541 tcgaaaaatt cgtcgcatca tgaaaagacg aggattgaaa tccagttaca cgaagcccaa
      601 atatcgcgta cattcgtgcc aaagcaatca aaagaaaatt gcgaatcact tagatcgaaa
      661 gtttactcaa acaaaagcat tgtcagcggt tgtcacggat ttaacttatg ttcgggtcgg
      721 gacaaattgg gcttatattt gtttgatgat tgatttattc aatcgtgaaa ttattggcca
      781 ttcttgcgga aataaaaaag atgcgcagct tgtaaaaagg gccattcaaa gcattcctta
      841 ctcacttcaa gaaatcgaac tcttccatac ggatcgtgga aaagaatttg ataatgaatt
      901 gattgatctt atcttagaaa catttggcat tcaacgctcc ttgagtaagc ctggatgtcc
      961 atatgataat gccgtttcag aagcgactta caaagctttt aagacggaat ttgtgagtca
     1021 atatcaattt gaaacgatgg cacacttaga attagaatgt tttgattatg tcaattggtg
     1081 gaatcatcat cggatccata gttctcttgg ttataaaaca ccaattgagg tacgctatgc
     1141 ggaggttggc gtagcgaacc cttgataatg agcaagaatc ggttaccttc tgttcgagcg
     1201 gcttatttta ttcaaagtga gcacgccgct aagaaaaccg atttgaggag gctcgttgtc
     1261 aagggcaact ggatatggtg tcataaacag accttataat ttttgtctag aaaagtgttg
     1321 ccattccata catctagagt tattttatat ccccttgaaa gtcaggagtc ttgtaaagaa
     1381 taatgaaaat attaagactt ctgaaattaa gtcgggtcac acttctgtaa atagttcaga
     1441 cgaaattatt agtagtagaa aagtaaatgg ttggaaaatg attcaattag gagaagcttt
     1501 aaaaaatgag cggtcgtttt tataaggtta atatggtata cttagttata atatcttttt
     1561 tgaggagata gctatgtata aaacagcaaa tgaattattt aatcgattaa aatcagaaaa
     1621 aaaagaactc attttaaact atatcttaga agaatttgga agagttggtt atgaatctgc
     1681 ttcagttcgt aagattgctg ataaggcaga tttaagtgca ggatcattat atcagtactt
     1741 taacaataaa gaaggaatgc taagagtagc aatagaacac gtttttgtta ttttagatga
     1801 atatattaat aatataaaca atgctccttt aaaattagaa aatcgtttag aagtaatgtt
     1861 cgaaacaatc ttagaattag gaagaaaaca tcctgaattg attgtttttt ataataaaat
     1921 tcctggtgac gaacaaatga caagcgagtg ggttaaacaa ttttacaata acactagttt
     1981 tttcaaagta tattggcata ccgtaaatga attacaagat gaaaaagaaa taagtgataa
     2041 aattgatcca gttgtctaca cgttcattat tgatacgatg atgttatccg gagaattact
     2101 tcaaaatacg caatatcaag aaataaaagc caaaattttt ctagaagact caataaaaag
     2161 ttcattaata ttaaaagaaa atgttatcga gacgctaact gtacttgcaa gggggtaaga
     2221 gtctatgaca ataagtaata agaatagcat gcgagaagaa attataatta ttgctataaa
     2281 gcatttttct aaatttggtt atgagaaaac aagactttta gatattgcta atgaagctaa
     2341 aactagtact actactgtat atagtttttt taaaacaaaa catgatctgt atgaagctgc
     2401 agtggagtat gatttaaata taataaacct tgaacttgaa aaaattgtta aggaaagttc
     2461 tacactcgat gaatatatta taaatatagt tgaaagagta cgattaaatt ctgaaaagaa
     2521 acaattgttt ttgaattttt ttatgcttat ttcgaccaat tctggccaaa taaaaaaaat
     2581 agatattata gaagaatttg
//
LOCUS       DAXLPC010000159         2566 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.165, whole genome shotgun sequence.
ACCESSION   DAXLPC010000159 DAXLPC010000000
VERSION     DAXLPC010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.165"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(53..910)
                     /locus_tag="ACF3UE_002716"
     CDS             complement(53..910)
                     /locus_tag="ACF3UE_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFD3636040.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(1195..1482)
                     /locus_tag="ACF3UE_002717"
     CDS             complement(1195..1482)
                     /locus_tag="ACF3UE_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFD3636041.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKIIPVLLCGTHEKFYEQLKKLI"
     gene            complement(1472..1801)
                     /locus_tag="ACF3UE_002718"
     CDS             complement(1472..1801)
                     /locus_tag="ACF3UE_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFD3636042.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(1878..2150)
                     /locus_tag="ACF3UE_002719"
     CDS             complement(1878..2150)
                     /locus_tag="ACF3UE_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFD3636043.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(2150..2413)
                     /locus_tag="ACF3UE_002720"
     CDS             complement(2150..2413)
                     /locus_tag="ACF3UE_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFD3636044.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT          772 a          517 c          337 g          940 t
ORIGIN      
        1 tggcgagtcc tttattgttc ccaaaaatat caagtccttt gatgtcagcc aattactcca
       61 cctccgcata ccaattctcg tgttcttcca attctttcaa aatactgata aataattcgt
      121 ggcttttgcg atcccattgt tttaagagac ctttctttgt cttctccatc gtaatacctg
      181 atccgtcgta tcgttttaag cgcgcatttt tgagtacaac atttttaatc aaatgttccc
      241 cataaatctc ttgggcttgt ttatacattt cctgatctac tgcgtcaccg ctttccaaca
      301 tgaaaggaat aacaccagca acatataaat ttgtatcaaa ttctttcaca aaaaagtcca
      361 tatactcaag atattgcatc gcatttctca tcgattttac ttgggtctgt aagacgacga
      421 ttgcccagtc cgcaatgtac atcgcggatt tactatatac agaaatagaa ggtgggacat
      481 ctaaatagat gacgtcaaac tcatcaaata atggttctag cttttctttc atatatttga
      541 attgggataa tgaatcatta tattggtctt tgatccaatc atcatacatt tcaaaggaca
      601 tgtctgctgg aagtatatag aggttattga ttactttata gacagcctct ttaggtggaa
      661 gattgtttat caacacgtca gtcacagtat tttcgtaaac aatcggttca ccttctccgc
      721 ctccttcttc gttagtgaag ttcatatgcg ttaagttcat cacatcagaa gtatttcctt
      781 gcatatccaa gtcaattatc aaggttcttt ttccttcatt aactgctgat tcaaacccta
      841 acatttgcgc gcacgtactt ttacctacgc cacctttaaa attaccgatt acatatttct
      901 tcgctaccac gttcctacct cttttctttt agcaatattc atttgatact attataacat
      961 atttattttt agttactacc aaaaaaagat atatatgtac taccttataa ttaataagga
     1021 aaaggtagta cataaataag gaaaagctga aatatattga tttatagctt tcctcaaagt
     1081 aatgacgtta tttaatttat cgagaagcag agaatactcg cgactttagt catgtagacg
     1141 aatcagattt tcgataaaaa agaagccgtc cttcttaaga acgacaacaa atcactagat
     1201 taattttttc aactgttcat aaaatttttc atgcgttcca cataacaata ctggaataat
     1261 cttgttttct ataatctcgt aagctactct atatgttgtg cccgcatatt taaacccact
     1321 agaccaaata cctgataaat ccccagtttt ttgttcaccc ttatatggat caatcgcaat
     1381 ttcatcataa attaaattca aaaatttttc tttcaatggc ttctctttta gcttttttaa
     1441 atacttaatg acatgttttg aaggaacgat ttcataagcc aatttctgtt gccaactcct
     1501 ctttagtcat tactttagaa ttagtaagtg tatcttcagc aatatctcta aaggaagaat
     1561 gcattttgtt ttttctattc ttaaattcta caagaatctc atctttatcg tagccttctg
     1621 caattatatc agacaaaata tcttcgctaa aatcataaaa ttctttttgt ggttcaacaa
     1681 attcataaag aataccattc tctaccaact ttgcttcaac ttcgactcca ttaggaacat
     1741 taaaatcttt aggtactgtc aacatgattg aattgccttg ttttcttgtt tttgtaatca
     1801 tttaaatccc tcatttctaa cagtatgtaa ttacttagta aatacattat accacgagat
     1861 aatgtattta caagtaatta ctgtgactcg taatgcgtcc ttgctgaata aatttcaacc
     1921 acgtgttcat cttcatctac cttataaaca acccggtgtt gtctattcaa tcttctagaa
     1981 tacctacctt catgtgtagg ttttaacttc tcaaatgatt gggtagggag atagggatct
     2041 tcctttaaag tctgaataac cttctcaaat tgaggtttca aattagactg tttgattttc
     2101 tttaaatcag ctttagccga gtttttaatc atcacagaat agttattcat tataagttat
     2161 cccaatcaat ttcatcaaca ttagtaaatc cactatcatc tttttctcgc ttacgaacaa
     2221 cacccaaagt gcctatttgc tcaagtaata gcgtttcttt gattgctttc caatcatcca
     2281 aaccaataag caccgcatta ttttcactgc gctcactaat gatttcaatt tccgtatgat
     2341 tctcatttac atctttcaac aacttataaa aatttttccg tgctgagcta ggatttaaga
     2401 ctgtttttgc catatctact ccccctctaa tttatatctc cattctaacg tacttaatta
     2461 agtacgtaaa ttcgattgtt ttgtttaaat tggagtacca aaacagcatt gtaaagtgtt
     2521 atccgtttcc tttatacccg tggtgctagt taattttttc ctagag
//
LOCUS       DAXLPC010000160         2509 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.167, whole genome shotgun sequence.
ACCESSION   DAXLPC010000160 DAXLPC010000000
VERSION     DAXLPC010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.167"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(489..614)
                     /locus_tag="ACF3UE_002721"
     CDS             complement(489..614)
                     /locus_tag="ACF3UE_002721"
                     /inference="COORDINATES: protein motif:HMM:NF019687.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636045.1"
                     /translation="MLFPPFKSSKSRKNPSDKYSYHWDFNTKIAVYYTLIATDAL"
     gene            599..>2509
                     /gene="tet(S)"
                     /locus_tag="ACF3UE_002722"
     CDS             599..>2509
                     /gene="tet(S)"
                     /locus_tag="ACF3UE_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HFD3636046.1"
                     /translation="MEEIKLKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSG
                     TTKTDTMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAIL
                     LISAKDGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIK
                     QTVNLNLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSL
                     YPVYHGSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLY
                     SGTLHLRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGD
                     KKRLPHREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIV
                     LSFLGEVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASI
                     GLSVTPLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKY
                     GLYYSPVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKY
                     CANILNTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAF
                     QPRRPNNRIDKVR"
BASE COUNT          900 a          372 c          441 g          796 t
ORIGIN      
        1 atgatatttt ccaagtcaaa cttaatatta acaattcaaa actattggaa ccactgcaaa
       61 atattttgtt aagcagtata tatttcaaaa attatacgta atatatttgt agaaaggttg
      121 tggacagttg tcctattgac ctgaaaagta atataatagc tggatgaata aagaatccct
      181 tatgaacttg taaatcgtta ttaaatcgct gaattttgat agccattctg aagagttatc
      241 ttcaactact acactaactt ccattaattt ctcattaatt tccctttcgt tcaaaaaata
      301 tggttggctt tacaagcatt ctatcatatg atagaattaa gataacattc aaaaggagat
      361 aataaaaatg cggcaaggta ttcttaaata aactgtcaat tagatagcgg gaataattaa
      421 ttaagcatcc ttatttaaaa taaggactgg ttttttgtgc ccagtttaag aatactttta
      481 tcattttatc ataaagcatc tgtggctatc agtgtgtagt atacagctat ttttgtatta
      541 aaatcccagt gataagagta tttatcactg ggattttttc tgctttttga gcttttgaat
      601 ggaggaaata aaattgaaaa ttattaatat cggtatctta gcacatgttg atgcaggaaa
      661 aactactttg acagaaagct tactatacag tagcggagca attaaagagt taggaagtgt
      721 agatagcggt acaacgaaaa cggatactat gtttttggaa cgccagagag gtattactat
      781 tcagaccgca ataacatctt ttcaacggga aaatgttaaa gtaaatattg tagatactcc
      841 tggacacatg gattttttgg cagatgtata ccgttcatta tctgttttgg atggagctat
      901 tttgctaatc tctgcaaaag atggagtaca gtcacaaact cgtatactat tccatgcact
      961 tagaaagatg aacataccta taatattttt tattaacaaa attgatcaaa atggaataaa
     1021 tttgccagat gtttatcaag atattaagga caaactttct gacgacatca taattaagca
     1081 gactgtgaat ctaaatttga aaccttatgt aatagattat actgaaccag aacaatggga
     1141 gacagtaatt gtgggaaatg attatttatt agaaaaatat accattggga aaacattgaa
     1201 tattgcagaa cttgaaaagg aggaaaacga aagaattcaa agttgctcct tatatcctgt
     1261 ttatcacgga agtgcaaaga ataatattgg aattaaacaa cttatagagg taattactag
     1321 caaattattt tcacccacac aactcaattc agataaactt tgtggaaatg tttttaaagt
     1381 agaatattca gatgatggtc aacggcttgt ctatgtacgt ctttatagtg gaacgctaca
     1441 tttgcgagac tcagtcaata tatcagaaaa ggaaaaaata aaagttacag aaatgtatac
     1501 ttcaataaat ggagaattac gccagataga taaggcagag cctggtgaga ttattatttt
     1561 aaaaaatgag cttttaaaac taaataacgt acttggagat aaaaaaagat taccacatag
     1621 agaaattctt gagaatcctc ttcctatgtt acaaacaaca attgaaccat gtaaatcagt
     1681 acaaagagaa aagttactag atgcactttt tgaaatatcc gatagtgatc cccttctaca
     1741 atattatgta gatacagtaa ctcacgaaat tgtgctatct tttttaggtg aggtccaaat
     1801 ggaggtaact tgtactctga ttcaagaaaa atatcatatt gagatagaaa caagaaaacc
     1861 aactgtcatt tatatggaaa gaccattaaa aaaatctgaa tttaccattg atatcgaagt
     1921 acctccaaat cctttctggg cttctattgg tttatctgta acaccacttc ctttgggtag
     1981 tggcattcag tatgagagcc tggtttctct aggttattta aatcaatcat ttcaaaatgc
     2041 agttatggaa ggtatacgct atgggtgtga acaaggattg tacggttgga aattaacaga
     2101 ctgtaagatc tgttttaagt atggtctata ttacagccct gtcagtacgc cagcagattt
     2161 ccgaatgctt gcgcctattg tactagagca ggcttttaga aagagtggta cagagttatt
     2221 agagccatat cttagcttcg aaatttatgt accacaagaa tatctttcga gagcatataa
     2281 tgatgcttcc aaatattgtg caaatatttt aaatactaag ttaaaaggta acgaggtcat
     2341 tctcattggt gaaattccag cccgttgtat tcaagagtat cgaaacagtt taactttctt
     2401 tacaaatgga cgcagtgtct gtttaacaga gttaaaaggt tatcaggtta ctaacattaa
     2461 gtctgctttc caaccacgtc gtccaaataa tagaatagac aaagtaagg
//
LOCUS       DAXLPC010000161         2408 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.168, whole genome shotgun sequence.
ACCESSION   DAXLPC010000161 DAXLPC010000000
VERSION     DAXLPC010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.168"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            150..2315
                     /gene="acm"
                     /locus_tag="ACF3UE_002723"
     CDS             150..2315
                     /gene="acm"
                     /locus_tag="ACF3UE_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HFD3636047.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
BASE COUNT          950 a          358 c          461 g          639 t
ORIGIN      
        1 gcatatttat tttttataaa tatttgtaaa ataactatca attttttagt taaaagattg
       61 gaaatgagtg ggggaggaat tgaagaaagg atttttgaga gatgatatag taggttttat
      121 ttttagttaa aataggggag atagaaaaaa tgaaaaagtg tagaaatatt attttatcaa
      181 tgttatttat tattactaat ataacatcac tgattcctgt tcatgtctat gcggatgcag
      241 gcagagatat cagcagtaat gtcacttcgt tgaccgtgga cccaacgaat attacagatg
      301 gaggaaacat aaaagtaaaa ttctcgtttg acgaaaaaaa acaaaatatc caaccaggtg
      361 attatctttg gatcaattgg ccaagtgaag gaaatattcg cggtgaagga ttccaaaaag
      421 aaatcccatt aatgattgaa aataaaaatg ttggaacttt aacggtcaga aaagattctg
      481 cgcaggttgt gtttaatgaa aatattaaaa acctagactc agtagaaggt tgggggcaat
      541 ttgagataca ggccagaaac gtaaccgata ccggtgaaga aaatacggga ccattcaccg
      601 tgacgagcgg tgataaaaca gctactgtaa atgtgacaaa gccagcttct ggttcttctt
      661 ctagcgtttt ttattataaa acaggagaca tgctacctga agatactaag cacattcgat
      721 ggtttttgaa tattaacaat aacggcactt atgttgaaca accagttaaa atcagtgatg
      781 aaatccaaag tggacaaaga ttagatccaa gtacgtttga aattaatcaa atacacttag
      841 gtgaacagaa ggtttataga ggagaagagg gaatccaaca atttttacaa gatttcccca
      901 gcgctacatt taatttttca gtaactgata attacattga aataactata ccaaaaaact
      961 ttgtcaatct taggaaaata atggtgagtt ataagacgat catagaaaac ccagaacaaa
     1021 taaattttga gaatcattcg gaagcttggt ttaaagaatt taataaacct gctgttgatg
     1081 gagaaagttt caatcataca gttaaaaata tttcagcttc tggtggagtc aacggtacag
     1141 ttagaggcga attgaagatt ttcaaatata tcaatgacac agagattggt atcccaaatg
     1201 tgactttcga attaagacga gcagatgaac agcctattca aggacagtct agtatcctgt
     1261 tgacttcgaa tgaacaggga gaagctagta tcaaaggcct gcaagtagga gactatgttg
     1321 taaaagaaaa agaagcaccc aattggattg attttgatcc actaagttca aatgaactca
     1381 aattctccat aaacgaaaat gatacagagg gagtcagttt acctatttat aacaagaaaa
     1441 aggttacgaa catcacagca actaaaattt ggaacggtgg aaccactcca agaccgagta
     1501 tttattttaa attattcaga gcaagtacaa acaattggga accagttcct gatgcagaaa
     1561 caaaacgatt agacaatgga ataacttcag tgacttggga agatatccaa cagtatgatg
     1621 atagtggaaa cgaatatacg tttaaagtgc aagaagtaga tcaaaacgga aatgattatg
     1681 tcccttcagg ttatcaaaaa attgaaaacg ggctagtcgt tacaaatgag aataaagaag
     1741 tcatttcagt ctcaggacaa aaaacatggg aagacaatga gaaccaagac ggcaaacgac
     1801 cgacgacgat cacagtaaat ctattagccg acggtcaacc gatccaacac aaagaagtaa
     1861 gtgaaaaaga tgattggcgc tatcgtttca caaatctgcc aaaatacaga gacgggcaag
     1921 aaatcatcta tactgtaacg gaagacaacg tgcccgaata cagtacgacg attgacgggt
     1981 ataacatcaa aaacagttat acaccggaaa aaacaaatat atctatacca ggtagccata
     2041 taacaccgtg gaaaaatttt ccagagaaga cagagagaga gaaaattaga aatctattct
     2101 ctcaaaaatt gcaaatattt gctcatacag gagaatccag cgaacaaaga agcaattata
     2161 ttagtaagag agctgtacct aaacagataa caaataaatc aaaaagcatt cttcctaaaa
     2221 caagtagtaa aaaatctagt tttgctgtaa tcattggttt attgatagta actatctgtg
     2281 ctgggatatt cttacaaaaa tataaaaaag tttagttaga atataatatt ttttgttaaa
     2341 tatgactgaa atcaaaagaa taaaattccg atttataatc gaaaaaagaa gcatttttat
     2401 atatgctt
//
LOCUS       DAXLPC010000162         2293 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.169, whole genome shotgun sequence.
ACCESSION   DAXLPC010000162 DAXLPC010000000
VERSION     DAXLPC010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.169"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..674
                     /gene="wzy"
                     /locus_tag="ACF3UE_002724"
     CDS             <1..674
                     /gene="wzy"
                     /locus_tag="ACF3UE_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HFD3636048.1"
                     /translation="WAYTQYKGTFNYKKLIKWLILAVIGIYILNVITKARDGGGLSKL
                     TLKDFTSVFDSDDSPLVDSFFEMGGTMSIITFFLISGNGIYPFANTYLTSLLGSISTR
                     MLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNGGYIGGIVYIFIIGIVIGKI
                     LSNSIDNQDIENHPMKMFLAITTANIIMGFPRAASYLIVKNFVYGVLIILLINFFLQQ
                     FNKRL"
     gene            720..2225
                     /locus_tag="ACF3UE_002725"
     CDS             720..2225
                     /locus_tag="ACF3UE_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFD3636049.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWARKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIKCAVIVFICIILVNVLFYRRYVVKIISKIIVKIKKI"
BASE COUNT          768 a          306 c          386 g          833 t
ORIGIN      
        1 tatgggcata cactcaatat aaaggaacct ttaattataa aaaattaata aagtggctta
       61 ttttagctgt tataggaata tatattctaa acgtaataac gaaagcacgt gatggtggag
      121 gactaagtaa acttacttta aaagatttta catctgtatt tgattcagat gattctcctt
      181 tagttgattc tttttttgaa atggggggga ctatgagtat tataactttt ttcctaataa
      241 gtggtaatgg aatatatccc tttgctaata cttatttgac ctcactctta ggctctatat
      301 caacaagaat gctatcaatg tttggaataa agtttgtttt attagctgat tggttttctc
      361 aggattattt aggaatcact tgggggactg gattctcaat gattgcagaa gcctatgtca
      421 atggtggata cattgggggt atagtctata tttttattat tggtatagtc atcggtaaaa
      481 tcctttctaa tagtatagac aaccaagata ttgaaaatca tcctatgaag atgtttttgg
      541 ctataactac agcaaatatt ataatgggtt ttcctagagc tgcttcatat ttaattgtga
      601 aaaattttgt gtatggtgtt ttaattatat tgttgataaa ctttttccta cagcaattta
      661 ataaacgtct ttaatattta agcttaataa aaagataaaa caagtcagga gttgcaaaaa
      721 tggaaagaac tgctcggctc aaaaaaaaca ctatttgggc tctggtgttt caaataactt
      781 ctattgtctg tggtatgatc ttgctacgtt tgatattaac aaagtacgga tccgaggtta
      841 atggaatgat tagctctatt aaccaatttc tacaaattat ttctttttta caattaggag
      901 taggcgctgt aatgcaatca actctataca aaccactagc agaaaaggat aatttaatga
      961 taagtcaaat cttagcttct ggagggaagt tttatcggca aattgcatat attctactag
     1021 tatacgtggg tttgttactt gcagtctatt atgttctcgt tcctaatgaa tttgggagat
     1081 catatacaat ggcaatgatt gcaacattaa gtattaattc atttgctcaa tattattttg
     1141 gtattgttaa tactttgtta ttaagtgctg accagaaaat ttatattacg tatattgcac
     1201 agacaatagc atttatttct aatacagttg catgtgcttt attaattagt ctgaacacag
     1261 agatccttat ggtaaaactt attactgcta taatttatct tgcttgtcca atatattata
     1321 gatggtatgt ggatcgaaac tataatataa agaggaatgt gtcatatgat aaggaaccga
     1381 tccctcaaaa atggaatggg gttgcacaac acgtagcttc tgttgtacta gatagtactg
     1441 atgttgtagt gttatctata ttttctaacc tgatatatgt atctatatat aatgtgtaca
     1501 atttagtaat atacggagta aaacagctat tcatggctat gacaaatggc gttcaggcct
     1561 tactagggga actttgggcc agaaaagaaa tagaagttct ttacaaaaca tttgcatggt
     1621 tcgaatggat tgtacatact ttgacagttt ttatttttgg ctgtaccggt atactaatcg
     1681 ttccatttat tcaagtatat acaagaggag taacagatgc taattataat caattatcat
     1741 tcgcagcttt acttgtaact gctaacgcac ttcactgtct gcgtacacct tatcatgtaa
     1801 tgataaaagc agctggtaaa tataaagaaa ctcaaaatag ttttataatt gcttctttgt
     1861 taaatttagg tttatcatta attttggtta aaccactagg gctagttgga gtagcattag
     1921 gatctctaat ttcaatcaca tatcatacac tttggagtgc aaattataat tcaaaatatt
     1981 tgcttaaatg gccgatgaaa aaattctata aacagttatt tgtaaacatc ttaactgtag
     2041 ttctttcttt tggggcgaca tcacaattga aaatgatgtc aatcacatat ttggattgga
     2101 ttgttctcgc aattaaatgt gcagttattg tatttatatg tataatccta gttaatgttt
     2161 tattttatag aagatatgta gtaaaaataa ttagtaaaat catcgtaaaa ataaagaaaa
     2221 tttaatacac aataaatgtt ttaataaact taataaaatt atatttgcca aaattagaca
     2281 catatattaa att
//
LOCUS       DAXLPC010000163         2286 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.170, whole genome shotgun sequence.
ACCESSION   DAXLPC010000163 DAXLPC010000000
VERSION     DAXLPC010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.170"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..1082
                     /locus_tag="ACF3UE_002726"
     CDS             <1..1082
                     /locus_tag="ACF3UE_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFD3636050.1"
                     /translation="KILIMANNDDGLYRFRGMLIKNLVDQGNEVIVSLPKGKNIPKLI
                     ELGCQIIETPIDRRGINPKTDFKLFFNYCNILKKIKPDMVIAYTIKPNIYGGLACRLR
                     KVSYALNITGLGTAFQKKGVLKSLIVFLYRLAAKKSKVIFFENFENMKTFQTLQIAKQ
                     SKYKLLNGAGVDVEHFSYLEYPKDEQVHFLFIGRIMKEKGVDELFEAMKNLYSEEKNC
                     VLDVLGYFEEDYGIKIEKYEKEGWLKYHGYQSDIRPFVERAHCFVLPSWHEGMANTNL
                     ESAASGRPIITSDIPGCKEAVIESKSGYLCERKNSCSLYNSMNKFLKLSYEQRINMGK
                     MGRNYMIKKFNKKKVVDETIKSLFS"
     gene            1089..1484
                     /locus_tag="ACF3UE_002727"
     CDS             1089..1484
                     /locus_tag="ACF3UE_002727"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFD3636051.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            1481..>2286
                     /locus_tag="ACF3UE_002728"
     CDS             1481..>2286
                     /locus_tag="ACF3UE_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3636052.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKIGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKNKIINLIYPKLIEDEHGE
                     YFSPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAV"
BASE COUNT          893 a          258 c          439 g          696 t
ORIGIN      
        1 aaaaaattct tataatggca aacaacgatg atggtcttta ccgttttcga ggaatgctca
       61 taaaaaactt agtagatcaa ggtaatgaag ttattgtatc tcttccaaag ggcaagaata
      121 ttcctaaatt aattgaactt ggatgtcaaa ttattgaaac tccaatagat agaagaggaa
      181 ttaatccaaa aactgacttt aaactatttt ttaactattg taatattttg aaaaaaataa
      241 agccagatat ggtcattgct tatactatca aaccaaatat atacggtgga ttggcatgtc
      301 ggttaagaaa ggtttcttat gcattaaata taaccggatt aggaacggca tttcaaaaaa
      361 agggggtttt gaaaagtctc attgtatttt tgtatagatt agcagctaaa aaatctaagg
      421 tcatattttt cgaaaatttt gaaaatatga aaacatttca gactttacaa attgctaaac
      481 aaagtaaata caagctatta aacggtgcag gagtagatgt agaacacttt agttatttag
      541 aatatcctaa agatgagcaa gttcattttt tatttattgg aagaattatg aaagagaaag
      601 gtgtagatga actttttgaa gcaatgaaaa acttatatag tgaagagaaa aattgtgtac
      661 ttgatgtcct tgggtatttt gaagaagatt acggcataaa aattgaaaaa tacgaaaaag
      721 agggatggtt aaaatatcat ggatatcaat ctgatattcg tccctttgta gaaagagcac
      781 attgctttgt tttgcctagt tggcacgaag gaatggcaaa tactaacctt gaatcagcag
      841 catcagggag accaattatt acaagtgata tcccagggtg taaagaagca gttattgaat
      901 cgaagtctgg ttatttatgt gaaagaaaaa atagttgtag tctctataat tcgatgaata
      961 aatttctaaa attatcatat gagcagcgca ttaacatggg aaaaatgggg agaaattata
     1021 tgattaaaaa atttaataag aagaaagttg tcgatgaaac aattaaatca ttatttagtt
     1081 aaaaagatat gttttgcaaa gtatgtgata gaaaagaggg attctgtggc ttcagaatag
     1141 atatcaaaga attggcaaaa gtttctgata tttttttatt tactacatta caagaaggaa
     1201 tgccaagatc tatgatggaa gctatggcaa gtggattgcc atgtatagca agtaaaatcc
     1261 gaggtaatgt agacctttta gtggaaggaa aaggtggata tcttgttcca gctaaagatg
     1321 cagaattagt agcagagtgt ttgagagaac taatcaataa taaatctctt agaaagtata
     1381 tgggaaatga gaacctttcc agaattaaag aattcgaggt tagtatcgta aaaaaaagaa
     1441 tcaaagaaat atatgaagaa gttataggtg agagtgtaaa atgaaaaatc caatgttttc
     1501 aataatagta cctatctatt gcgttgaaaa atatttgaaa gattgcttag attcaataag
     1561 aaatcagaca tttaaaaatt ttgaagcaat actagttgat gacggtagtc ctgacgaatg
     1621 cccagaaata tgtgactatt attcccaaat agatggacgt ttaaaagtaa ttcataagaa
     1681 aaatggtgga ataatagatg cacggaaaat aggagtcact agtgctatgg gagagtatat
     1741 agtttttcta gatggtgatg attggcttgc aaatacttat ttagaaaaat atgcggaagt
     1801 aattactaag tacaatccag atataatatg tagtgggtat tttgcatcac gttccaacaa
     1861 aattagaaaa agagaattgt cttgctcgtt tggatattat gacaaaaata aaattataaa
     1921 tttgatttat cctaaattaa ttgaggatga acatggagaa tattttagtc cacaattatg
     1981 ggcaaaagct tttagaacta ctctgtacaa ggagcaacaa caagtatctg ggcaagttag
     2041 tgttggtgaa gatcatgcat gtacaaaacc atgtatttac catgcaaatt cgatatatat
     2101 gatggaaaaa tgtttatatt attacagaat aaacgaaaat tctataacaa aaaaaccaca
     2161 accatattat tgggaaggac caaaggctat tggagagcat tttgaaaagc agattgatat
     2221 gaataagtat gattttcaag atcaagtata tagaaatgtt acacacaatt tatttaatgt
     2281 tgctgt
//
LOCUS       DAXLPC010000164         2271 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.171, whole genome shotgun sequence.
ACCESSION   DAXLPC010000164 DAXLPC010000000
VERSION     DAXLPC010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.171"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            192..446
                     /locus_tag="ACF3UE_002729"
     CDS             192..446
                     /locus_tag="ACF3UE_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFD3636053.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            447..764
                     /locus_tag="ACF3UE_002730"
     CDS             447..764
                     /locus_tag="ACF3UE_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFD3636054.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1323..2258
                     /locus_tag="ACF3UE_002731"
     CDS             1323..2258
                     /locus_tag="ACF3UE_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636055.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          823 a          307 c          430 g          711 t
ORIGIN      
        1 ggatgttaac ggaagtgtat ggtgagtagt tcactcgtat tttgatatcg tttgtatatg
       61 ttttcagcgt tctaagtggc ttattttgtc caataataat atggagtgga atcccttaag
      121 aaacaccgtt ggcaattgtt gttataacat gttataattt attcatcaaa aactaaaagg
      181 agtgtgataa catgggaaaa gaactaaagg ttagaaagat cggcaatagc gtgggagtga
      241 tccttccaag ctctcttgga ttaaaaagcg gagacattat ccaagccaaa caagaaggca
      301 acttattcat attagatact actcaaatag caaaagaaca cgatcgcaaa ttgattgaag
      361 aaagtttcca agactttgag aaaggtttaa cagtttcaga aattgaaatg gtaaaagctt
      421 tcggaaaata cggctggagt gaatagatga aagagtacac gctagtttat tctaaaagtt
      481 ttcagaccag ccttgaaacg ataatagaag aatgggaaaa tgagcttgct ctttctccag
      541 ccagcataaa aagatttgta ggtgcgatcc agaaggcttt agaactaacc aaaaattttc
      601 caactatgca tgaggaagtt tccgaaatct atggaatgga tatcccaaca tatcggatcg
      661 tgatcggcaa aagctatgcc ttattttatc ggatcgacca tgaaaaaaaa gagatacttg
      721 taggacgtat tttccaatct aaacaaatga aactaggctt ttaacaataa ttaggaaaaa
      781 gtcgctcatc ctctacaggt gggtgattaa tgccgctcga tatggttgtt aaccgtcggt
      841 tactcgaaga ttgatatata agacttagta cctttttatt ttgctccatg ttatggccga
      901 aggtctaaag atacaatcat tagtctagag aaaaattaag aaccgtagga actacgggga
      961 tcgcttggtg aataagagac actgctatta gtgaaaaaat aagatatcaa gtacgctcta
     1021 ttcccaaaaa tttcgtgact ttactcatga gaggttcaag tagtatattt ttaatcaaaa
     1081 ttgacgtaac ttttaataaa tactacctaa ataaggtagt atttattttt gtgttttaaa
     1141 agaggaagtc caatatatct atgggaaact tcttaaatat tatgttggta catgaaaata
     1201 tacatccctg ctagactatt tacaacattt tactttgtac gtattcttgt tttaaaagga
     1261 atgggataaa atataggtac aataactatt tgatgctaaa tataattaat ggaggagaga
     1321 tagtgaacat acttaatgaa aaaagatatg tatggtttgc tggtaaaaaa tatattacta
     1381 ctttcaaaag attatccgag ttaatgcagc agactgttaa aagtgctatg cctgaaggat
     1441 acaagtttaa ttttgttcaa tcttcagtat ctactgaaag tatctatttt tcaattcttt
     1501 ctgagagtag gctttttcat tttagaataa gttctcatgt aaagaaaact gatgttgata
     1561 tatatacgtt ccgtacaaat aattataaaa atttaaatga tttgagtaga agtatcagtg
     1621 aatatctcaa ggggaatagc tatctcaaga ttcgattttc acatatatta attttactac
     1681 catatttgaa tgagaatttc accctaattc aagtagataa gtctttcatt gcctcaggta
     1741 atcaaggaaa tatgaatatt acaagtaaca aaacgtcacg tgtgctattg gcgttgatgg
     1801 gttacggaat tctttataga gatgaccaaa atggccagat tctaataaat cgggctgggc
     1861 gttcattatt aatgaaatat agaaaattta taccggaaga ttttcaaaac ttacagttag
     1921 aaaacatgcg tttagaagat ttatttagat tagcagaaga tgataagtat agatttgaag
     1981 ttttgaaaat tcaaaagaat gaactattga ataagttata tcctgagaat gcgataaaag
     2041 cacattttgg tgatgctaat catatgtata gttggttcat tcctaaaaga tttagaggga
     2101 aaatcaatgc tggagatcaa gtgaaagtac tcaatcgaaa tagtacagat gtcgtaatga
     2161 taacagatat ctatgtagaa gatgaagata taatcaaata tatgaagcct gtgataaaac
     2221 ttgttaataa aaataaagga acccgtggtg ctagttaatt ttttcctaga g
//
LOCUS       DAXLPC010000165         2222 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.172, whole genome shotgun sequence.
ACCESSION   DAXLPC010000165 DAXLPC010000000
VERSION     DAXLPC010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.172"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>2222
                     /locus_tag="ACF3UE_002732"
     CDS             <1..>2222
                     /locus_tag="ACF3UE_002732"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636056.1"
                     /translation="IGAMFLGIGLISCPTVSFASETTEINQSTEIQSTLNNSILKESN
                     SEEKQNIDVSEDSAINKDLELASKATISESENSFGETTNNQENTNLSEDSIEVQPESI
                     IQKEVLTDNDAIQQLEVHPHEDSDDAALVENQMTRVTEESIKSNTSQVDKDTTVLSNT
                     TRDLVNLEDTAIENVTPQKTIKKDSISLLEENNSSSASRTLRRSVRSLDVQTGENFLE
                     DWALPDNSNISGSLITQTGITYVGVKTDDPTQLHLKMAYRAAATPASIDWIYLRVDPE
                     LTKYIEEINIKNTVNIGAQVGYQRYFEKVDTNTLSNVNTFGTPTGVSDAYAQVDQKTG
                     GIYRVLLDKFFIRIPGTNPKSRGALSGNWGVFPSVPLEAERYEANIYIKLSKDVAELQ
                     QELGRDKFGVQLRLQGQSSSGVATIAKESLNKNTIVDLSQEEPDENNSNWLNSPSVHT
                     ITTTYEGKQMGSDGQFSSILEGTDKSLIRVQNTIMNNLLYGTALDLGRPVSFNIEIDP
                     QILNLVSDDDYITIWQVYRENSINHHDGGSNAPVMLKKNMFVDNKIKIEVNKDKAGQY
                     GNGVYYVNAVESFMNTLSSSPFVGANFIDIPVMPKSLIEDEDQLISAEIKTWFTDKKN
                     DQERIVRNSLASSYINLFPTTINFYDYSTKDTEQLLKLRESTYLVSTFGQEINGMDMG
                     ETYEISNYEFVTADPESLIITQKDGNIINLYYKKLSSDAEFYEPEVEKEEVNYGETID
                     "
BASE COUNT          823 a          317 c          417 g          665 t
ORIGIN      
        1 ttatcggtgc aatgttttta ggaataggat taatttcttg tcctacagtt tcttttgcta
       61 gtgaaacaac agagataaat caatcaactg aaatccaatc tactttgaat aattctattc
      121 taaaagaaag taattcagaa gaaaaacaaa atattgatgt gtcggaagat agtgctataa
      181 ataaagatct agaactagct tcgaaagcaa ccatttctga atcagaaaat tcatttggtg
      241 aaactactaa caatcaagaa aatacaaatt tatctgaaga tagtattgaa gttcagccag
      301 agagtattat tcaaaaggaa gtcttgactg ataatgatgc tattcaacaa ttagaagtac
      361 atcctcatga agatagcgat gatgctgctt tagttgagaa tcagatgaca agagttacag
      421 aagaaagtat aaaaagcaat acttcacaag tagataaaga tacgacagtt ttatctaata
      481 caacaaggga cttagttaat ttagaagata ctgctataga aaatgttact ccacaaaaaa
      541 cgatcaaaaa agatagtatt tctttattag aggaaaataa ttcatcatca gcatcaagaa
      601 ctttacgtag aagtgttagg agtcttgatg ttcaaactgg agaaaacttt ttagaagatt
      661 gggcactacc agacaattct aacatttctg gaagtttgat tactcagact ggaattactt
      721 atgtgggtgt aaaaactgat gatcccactc aattacattt gaaaatggct tacagagctg
      781 cagcaacgcc tgcttcaatt gattggattt atcttcgtgt ggatccagag cttacgaaat
      841 atattgaaga aattaacata aaaaataccg taaacatcgg tgcacaagtt gggtaccaac
      901 gatattttga aaaagtagat actaatacat tgagcaatgt aaatactttt ggaactccga
      961 caggtgtaag tgatgcttat gcacaagtag atcaaaaaac tggcggaatc tatcgtgtgt
     1021 tattagataa atttttcata cgtattccgg gcacgaatcc taagagtcga ggcgcgctat
     1081 ctggaaactg gggggtattt ccatctgttc ctctcgaggc tgaaagatat gaagcgaata
     1141 tctatataaa attatcgaaa gatgtcgcag agttacagca agagcttgga agggataagt
     1201 ttggtgttca acttcgttta caaggtcaat caagttctgg tgttgcaact attgctaaag
     1261 aaagtttaaa taagaatact attgttgatc tttcacaaga ggagccagat gaaaataatt
     1321 caaattggtt aaactcacca tctgtccata caattactac cacttatgaa ggaaagcaaa
     1381 tgggaagcga tggtcagttc agtagtattc tcgaaggaac tgataaaagt ctgattagag
     1441 ttcagaatac gatcatgaat aaccttttat atggaacggc acttgattta ggtcgacctg
     1501 tttcatttaa tattgagatt gatccacaaa tattaaattt agtttcagat gatgattata
     1561 ttacgatttg gcaagtatac agagaaaata gtatcaacca tcatgacggt ggatcaaatg
     1621 cacctgtcat gttgaaaaag aatatgtttg tagataataa aataaaaatt gaagtcaaca
     1681 aggataaagc tggtcagtat ggaaatggag tttactacgt taatgctgtt gagagcttta
     1741 tgaatacttt gagttcttca ccatttgttg gtgcaaactt tattgatatt cctgttatgc
     1801 ctaaatctct aattgaagat gaagatcaat tgatatcagc agaaattaaa acatggttta
     1861 cagataaaaa aaatgatcaa gagagaatag taagaaactc acttgcttca agttacatta
     1921 atttattccc tactaccatt aatttctatg attattcaac caaggataca gaacaattat
     1981 tgaagttacg tgaatcaacc tacttagttt ctacgtttgg tcaagaaatt aatggaatgg
     2041 atatggggga aacatacgaa attagtaatt atgagtttgt gactgccgat cctgaaagtt
     2101 taataatcac acaaaaagat ggaaatatca ttaatttgta ttataagaaa ctttctagtg
     2161 atgctgaatt ttatgaacca gaagtagaaa aagaagaagt caactatgga gaaacgattg
     2221 at
//
LOCUS       DAXLPC010000166         2220 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.173, whole genome shotgun sequence.
ACCESSION   DAXLPC010000166 DAXLPC010000000
VERSION     DAXLPC010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.173"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(51..1598)
                     /locus_tag="ACF3UE_002733"
     CDS             complement(51..1598)
                     /locus_tag="ACF3UE_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFD3636057.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="ACF3UE_002734"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="ACF3UE_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFD3636058.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          622 a          465 c          397 g          736 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
//
LOCUS       DAXLPC010000167         2200 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.174, whole genome shotgun sequence.
ACCESSION   DAXLPC010000167 DAXLPC010000000
VERSION     DAXLPC010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.174"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..503
                     /locus_tag="ACF3UE_002735"
     CDS             <1..503
                     /locus_tag="ACF3UE_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636059.1"
                     /translation="SNLIFEGKNLFLNLTISFEKDYHKLDFKEGAELTIKFTDLCSGK
                     CLVNNQSVIDFGDSKYISNFKNKIKAMKSREQSRGVFSKGGHGRKRKLDQDRWEAIKK
                     RESNFVKTYNNQCSAKIIQTAIRNKTQIICISEPDKNYGEWAYYQLKEQIINKGKRYG
                     IEVKSE"
     gene            complement(1063..1440)
                     /locus_tag="ACF3UE_002736"
     CDS             complement(1063..1440)
                     /locus_tag="ACF3UE_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HFD3636060.1"
                     /translation="MKKSYPVIFSAEENGYSVVFPDFAGATQGDNFEEAMSNAKEFLD
                     GILAYYIDEDISVPSPTDIHQLNNLGNNKIVSLIQSDPSPFIQKKTVRKNVTVPEWLV
                     ARGEKDKINFSKVLTDALLKIYE"
     gene            complement(1486..1674)
                     /locus_tag="ACF3UE_002737"
     CDS             complement(1486..1674)
                     /locus_tag="ACF3UE_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HFD3636061.1"
                     /translation="MPLTGKKMLKLAKKNGWKVVRITGSHHIVAKEGFPPVPIPVHSN
                     QDLKKGTEQKLLKDLGLK"
     gene            1866..>2200
                     /locus_tag="ACF3UE_002738"
     CDS             1866..>2200
                     /locus_tag="ACF3UE_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3636062.1"
                     /translation="MNKKQDQEYYIEKLEKENLELKERIRYYETKFCKRGDCMKPNPV
                     ETGKRIKSIRSNFGMTMEQFADLIGNAQKGNINNWERGFSLPNKERLIKIAELSNKTI
                     DWIKWGTLE"
BASE COUNT          801 a          316 c          408 g          675 t
ORIGIN      
        1 agagtaatct aatctttgag gggaaaaatt tatttttgaa tttaacaatt tcttttgaaa
       61 aagattatca taagctagat ttcaaagaag gagctgaatt aaccataaag tttactgatt
      121 tgtgtagcgg taaatgttta gttaacaatc aatctgtgat tgattttggt gacagcaaat
      181 atataagtaa cttcaaaaat aaaattaaag caatgaaatc aagggagcaa agccgaggag
      241 ttttttctaa aggcggtcat ggtcgaaaaa gaaaattaga tcaagataga tgggaagcca
      301 taaagaaaag agaaagcaat tttgttaaaa cctataataa tcaatgttcg gcaaaaatta
      361 ttcaaacagc tatccgcaat aagacgcaaa taatctgtat ttctgaacca gataaaaatt
      421 atggggaatg ggcttattat cagttgaaag aacaaataat aaataaaggg aaaagatatg
      481 gaatagaagt taaaagtgag tagaataaga aatcgttgat ttggcaacga aatagtgagg
      541 ggacactcac tcactgaagg gttagctctg tcaagttgtg taaccagacg gaaggacgaa
      601 tattgttgag gttttagaac catgtaaaac aacacagttc tcaaatgtta cggataaacc
      661 gtttgcggga aatcaggttt taaaaccatg taaaacaaca cagttctcaa ataaggcttt
      721 attgaattga tcagtagttt ctgttttaga gttatataaa acgacatggc tcttaaatag
      781 gagctaacga agaaaaagaa ggtactccgt tttggagtta agtagaaata aaaaaataga
      841 atcgttgatt tggcaacgag ttgaaaaata cgcaaaacta tggtcaccaa gggataaccc
      901 tgaaactgat gatcgctata tcttactagt agttaaacag tctaaatagt actcatttat
      961 tgtattgatt ctaagggaac ctgcaataaa tgagtactat tttactttta attccgctat
     1021 ctatgtcatt aggcaactaa attgttatta atatatttac gtttactcgt atatttttag
     1081 taacgcatct gtcaaaactt tagaaaaatt tattttatct ttttcccctc tagctactaa
     1141 ccattctggg actgtgacgt ttttgcgtac ggtctttttt tggataaatg gagaaggatc
     1201 actttgaata agagaaacaa ttttgttatt gcccaaatta tttagttgat gaatatctgt
     1261 tggagaagga actgaaatat cttcatcaat atagtaagct agaatcccat caagaaattc
     1321 tttagcattg gacatagctt cttcaaaatt atctccttgt gttgctccag caaaatcagg
     1381 aaaaactact gagtagccat tttcttcagc agaaaaaatt acagggtaac tttttttcat
     1441 ttccaccact cctttcgagt taatccaatg aactaaagga ctgggctatt tcagccctaa
     1501 gtcctttagt aacttctgct ctgtcccttt ttttaaatcc tgattactat gaacaggaat
     1561 aggaacgggt gggaatcctt ctttggctac aatatgatgg ctgccagtta tcctcaccac
     1621 tttccaacca tttttcttgg ctagtttgag cattttttta ccggtaagtg gcattcgcga
     1681 ctacctcctt acaaatatta ttatacgcat tatgcgtata aaggtcaaga gtttttacat
     1741 taaaagtaga atgtaagtgt cacaataggg tataccctat tgtatcatat ggtaaagtac
     1801 agtataataa ggtttggagg tgtaacacta gggtgtaaca caatgtgaaa tttggaggtc
     1861 attttttgaa caagaaacag gatcaagaat attatataga aaaattggag aaagagaact
     1921 tagaactcaa agagcgaata agatactatg aaaccaaatt ctgtaaaaga ggtgattgta
     1981 tgaaaccaaa tcctgttgaa acaggtaaaa gaattaaatc aattcgttct aattttggaa
     2041 tgactatgga acaatttgca gatttaattg gaaatgctca aaaaggaaat attaataatt
     2101 gggaacgagg attctccctt cccaacaaag aaagattaat taaaattgct gaattaagta
     2161 acaaaactat cgactggatt aaatggggaa ctttagaaga
//
LOCUS       DAXLPC010000168         2169 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.175, whole genome shotgun sequence.
ACCESSION   DAXLPC010000168 DAXLPC010000000
VERSION     DAXLPC010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2169
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.175"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..300)
                     /locus_tag="ACF3UE_002739"
     CDS             complement(<1..300)
                     /locus_tag="ACF3UE_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HFD3636063.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            393..742
                     /locus_tag="ACF3UE_002740"
                     /pseudo
     CDS             393..742
                     /locus_tag="ACF3UE_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1014..1304)
                     /locus_tag="ACF3UE_002741"
     CDS             complement(1014..1304)
                     /locus_tag="ACF3UE_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636064.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..>2169)
                     /locus_tag="ACF3UE_002742"
     CDS             complement(1512..>2169)
                     /locus_tag="ACF3UE_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFD3636065.1"
                     /translation="AFLCLIGYTGTRYANEIILWGGETDIDTINENLTQLDHTLTDKE
                     QAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQNLESQLVSKDAQ
                     LQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNTVNGLNQQIATLT
                     QEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTADKSQQIVEEHLRK
                     "
BASE COUNT          612 a          408 c          323 g          826 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgagtttc tacatttgtt
     1681 ttttcttgtg tcagtgttgc gatttgttga ttcaaaccat ttacagtatt ttgtaattct
     1741 gaaagttttg cttgtgcttc ttgtagtctt gctgtccaat ctgcattcag atgattgatt
     1801 tcatcatttt tttggttgat ctcatctagt ttgacattga tttcattttg tttgctttgt
     1861 agttgtgcat ccttgctgac taattgactt tctaagtttt gtttttctgc tgccgattga
     1921 tttttttggt tttctaattc atttactttt gtttggtatt cttggacatc tgcctttgaa
     1981 tcttgcaatg tctgttcttt ttgtgctagt cgagcggtaa gatctgtaat cgcttgctct
     2041 ttatctgtca atgtatgatc aagctgtgtc agattctcat tgattgtatc aatatctgtc
     2101 tctccacccc acaaaataat ttcatttgcg taccgcgtgc ctgtgtagcc aattagacat
     2161 agaaatgca
//
LOCUS       DAXLPC010000169         2154 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.176, whole genome shotgun sequence.
ACCESSION   DAXLPC010000169 DAXLPC010000000
VERSION     DAXLPC010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.176"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..441
                     /locus_tag="ACF3UE_002743"
     CDS             <1..441
                     /locus_tag="ACF3UE_002743"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFD3636066.1"
                     /translation="LVPRIFGLTPYIIEDKEMSPYYAQGNLIYVRPKNTNEILVGDII
                     TYYENSGKKISTRRVIAVENNHEDFYTKADTKTYIEPGVVKKRNIIGSPIFQIPYIGL
                     VLSKTAFAWIQGLFFTIAFCLTGITAWNTFVELKKKRRRTQKFL"
     gene            569..1252
                     /locus_tag="ACF3UE_002744"
     CDS             569..1252
                     /locus_tag="ACF3UE_002744"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFD3636067.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1561..1634
                     /locus_tag="ACF3UE_002745"
     tRNA            1561..1634
                     /locus_tag="ACF3UE_002745"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1595..1597,aa:Arg,seq:tct)
     gene            1793..2152
                     /locus_tag="ACF3UE_002746"
     CDS             1793..2152
                     /locus_tag="ACF3UE_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFD3636068.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
BASE COUNT          714 a          337 c          444 g          659 t
ORIGIN      
        1 ttggttcccc gaatttttgg tttgactcct tatattattg aggacaaaga aatgagtcca
       61 tattatgcac aaggaaatct gatatatgta cgaccgaaaa atacaaatga gattttagtc
      121 ggagatatta ttacatatta tgaaaattca ggaaaaaaaa tctcgacgcg tcgcgtaata
      181 gccgttgaaa acaaccacga agatttttat acaaaagctg atacaaagac ttatattgag
      241 cctggagtag taaaaaagag aaatattatc ggtagtccca tctttcagat tccatatatt
      301 ggactagtcc tttcaaaaac ggcatttgca tggattcagg ggttattctt tacgattgct
      361 ttttgcctaa caggaatcac agcatggaat acctttgtag agttgaaaaa gaagcggaga
      421 cgaacacaga aatttttgta agaatgttaa aaacataaat gtattccaga gatccaacga
      481 ctcttctgaa catgaaacac gagaaaacac tcatgcagct tgtagattta gtcagttgtt
      541 cgtataatgt gtgaagagga ggagtagtat gcgcaatgaa atgatgcatc gtcctgtagt
      601 caaagaagaa ctattggatt ttatgcgtac ccagcaaaaa aaattaccgg gtgagctagg
      661 caaactggaa gaagaagctc atgtagcaga agtaccagtt attccccatg aaacagttgt
      721 atttttgaaa tttttacttg gacagcttca gcctgaacga atcttggaga tcggagcagc
      781 tatcggtttt tcatcaagtg tcatggccac gacaatcgga gaaaacgctc atgttacgac
      841 aattgatcgt ttcgatgtca tgatcgagaa agctaaaaaa aactatgaac gtctaggact
      901 gacagataaa gtgactttgc ttgaaggtca agcagcagat atcttgccgg agttgtctgg
      961 tccgtatgac tttattttta tggatagtgc aaaatcaaaa tatattgaat ttttacctga
     1021 atgcttacgt ttgttaagaa aaggtggcgt tttgatggta gatgacatct tccaaggagg
     1081 aacgatcttg ctcccagatg aagagattcc ccgtggcaaa cgagctatcc atcgtaaatt
     1141 aaatgaattt cttcgtgttg tgatggatca tcccgatttg acatcgacaa tcttgccatt
     1201 aggtgatggt gtgatcttaa tgacaaagga atcagaaaca atcgagttgt gatacatgat
     1261 tatggcagcc tgtagataat cgattgaatc gagggctcaa ttcgaacttg atgtaaaagt
     1321 ttctatattt gtaagtcaat taaaggatac aggaaatcta aataaacagg agtagcatga
     1381 agtcaatgta gctcctgttt tcaattgata accttagaac agctgaagga gaatgtctcg
     1441 ttttaaaaga ttgatttagt agttgggcca aaataattca ttatttgcta attaaataac
     1501 tatttcgtat tgacagaagc aatttaatta tctataatta ttgatgttcc gctgattctt
     1561 gtcatagtag ctcagctgga tagagcatcc gccttctaag cggacggtcg ggggttcgaa
     1621 tccctcctgt gacgctaaaa aaccgttaga aactgaggtt tctaacggtt tttctttgtt
     1681 ttttgtgcca atattgtttg ttttcaaagg caaataaaat aaaaaaacat ccttatcgag
     1741 tacaattata aggagcaaaa aaataaaact catcagaaaa gaggaagaag atatgacgat
     1801 actatctaga attttagtga ctctagttgc aattgaattt ttttatatca tgtatatcga
     1861 aacggtgaga actgattctg acacgacaag tagggttttt aaaatgagta aagaagagtt
     1921 aagcagaaaa tctgttcaaa cattgtttaa gaaccaagga gtgtacaatg gactattagg
     1981 agtgggacta ctttatggag cttatctttc ttccgcatct aaagaaatca caagtatgct
     2041 attaatatct attttttttg ttgcattata tggcagtttg actagcgatc gttggatttt
     2101 actcaaacaa ggtgggctag ctctgttggc attgctttct attttcttat aaat
//
LOCUS       DAXLPC010000170         2094 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.177, whole genome shotgun sequence.
ACCESSION   DAXLPC010000170 DAXLPC010000000
VERSION     DAXLPC010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.177"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            23..646
                     /locus_tag="ACF3UE_002747"
     CDS             23..646
                     /locus_tag="ACF3UE_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636069.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..>2094
                     /gene="trpX"
                     /locus_tag="ACF3UE_002748"
     CDS             1096..>2094
                     /gene="trpX"
                     /locus_tag="ACF3UE_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFD3636070.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAK"
BASE COUNT          741 a          346 c          446 g          561 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaa
//
LOCUS       DAXLPC010000171         2085 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.178, whole genome shotgun sequence.
ACCESSION   DAXLPC010000171 DAXLPC010000000
VERSION     DAXLPC010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.178"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            698..1030
                     /gene="traE"
                     /locus_tag="ACF3UE_002749"
     CDS             698..1030
                     /gene="traE"
                     /locus_tag="ACF3UE_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFD3636071.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            1649..1990
                     /locus_tag="ACF3UE_002750"
     CDS             1649..1990
                     /locus_tag="ACF3UE_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFD3636072.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT          730 a          278 c          435 g          642 t
ORIGIN      
        1 attatgataa aaatcacaaa cgtagccttt tacgtcataa gtgttaaaag aaataattaa
       61 tttcaaatat agaaaaggga acgtatgttt gcatactcct tttttttgag ttataataat
      121 acgcgaagag agataatttc attatttaaa caagctaaaa atcttgatat tacttctttt
      181 caggcaatac gaatattatt cgcttacatt ttttgtataa atttaattgt ctgctatgct
      241 tgtgatgaat tgattttcgt tttgcacttt tggatgataa atttggacaa ttgaaaatac
      301 aaaaaaaaga aaggcggtat gaactcggaa ggctggtaac cttcgtcagc gttcatacac
      361 ggcattaaga tttggccctt aatgcgttaa cctttcagtg ttacggtatt acccgcaatg
      421 gatttagtat aacagatatt caaaagtgat accacttttt ttggctgtgt taaggttaaa
      481 aatacgtgat attacgatga atctatgcct aagcataatg ttataaaaat gtccgtgtgg
      541 ctctttgccg tatgacgaac gctgaaatta gagggaacgc atgtttggat gcgttccctc
      601 ttttttgttt gtcatgaacg aaaatcaatt ctctattttt gaaaaataac aagaaaaact
      661 tgttaaaaat atttaaagaa attgggtggt ttattttatg tcatatacag gaattttgag
      721 tctcaaagat atttgtcact acggtaaacg gtgtaccgct acagagaaaa tcacgaagaa
      781 actatcaact ggccaaagta aaaccgttgt gcagtgtaag aaatatataa tccagaaaga
      841 caaagtctca gaggaaatga tttattacat tgggaaacaa aagcaaataa ttttaaaaga
      901 tcctatcccc ttaaaagagc tatatccaac aatcaaacat gtttatgacc aaaacggtgt
      961 actgattggt cgaagaaaaa atggagtctt gcgttgtacc gcaaaaggga tggggcgttt
     1021 gatcggctga attgatcatt ctcataactt gtattttatc gtttttcgct tgcttgaaaa
     1081 tattgtcgag acttctaaag gaacttagag tcactagaaa aataaggagt agacttgatc
     1141 tatcaacaat tcccttcggg gagtgacggg gtaggtttta acgattggta acgtaaaaaa
     1201 ttggtcaatc gagtaaatgc gcttgtttgg atagtggtga aatgaatttg tgtaaataat
     1261 aagcgcagag taaacaagag ggaatttaga agttagacaa gttagaatag cgtctagatt
     1321 aatcatgagc agctactaag ggatctagac tttgacgcaa actcatggaa taaggagtag
     1381 gtcttctcgt aatggggagg acgcacaaga aattgtgtcg tgtgctgcag tacatgtaga
     1441 tacttgcgag gacgttgatt attggatcaa tcgagcattt accgctgtct actagggttt
     1501 ctcgtttcgg acgccataaa cgagtcgaaa ttttttatgt atttttaagt aaacgaaaaa
     1561 cgataaaata tgaacaagtc ctgaataaag tgaaaaaatt aatataaagc atagagaaaa
     1621 tgaaatttac gtaatggagg aatgacaaat gaaaaattat gatccgaata tacgattggg
     1681 cacacatact attaaggttt ctttccaacg ttgggattac aaaggatttg tgacgtttag
     1741 aaggggcgga aattgtaaag gattagatgt tttagcatta gacgaggatg atttatacga
     1801 tcaaacattg actgataatc caattggatt cggcttgcta cctgaagatg atgaaggtaa
     1861 tgaatggttt aaaatgacgc ttatgaatga taatggagac gaattatctg ttgaagatac
     1921 ttggtcatat ttgagtgatt atattgtcag ctttgaaatc attgaatttg tagcggataa
     1981 agaagaataa aaactggagg aataaatttt acagataaag gcttagaagg agtcacgacg
     2041 attaataaaa aggtagtatt accttaggca ttgagtaagg aattt
//
LOCUS       DAXLPC010000172         2067 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.179, whole genome shotgun sequence.
ACCESSION   DAXLPC010000172 DAXLPC010000000
VERSION     DAXLPC010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.179"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..657
                     /locus_tag="ACF3UE_002751"
     CDS             <1..657
                     /locus_tag="ACF3UE_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636073.1"
                     /translation="QFLEELSGEEYRLFLNNNILKLISYAKKANSLSLVDNLDNLLPD
                     KLIYDENEDNSQKQIIIFELYLKWLSSLSVSPESNDDDKYFANKLFQFIFPDYSSMPF
                     FTLINFMLYVKEHLGYDDLVEMIKAYDKEPYPFKGINTGSDMAMISGETVEEILANYK
                     EQNIKTLELIKKNIKYYDPLLANKENIDKLLNAIADSDVRSPRIDELKEEILMYKELF
                     "
     gene            complement(654..1277)
                     /locus_tag="ACF3UE_002752"
     CDS             complement(654..1277)
                     /locus_tag="ACF3UE_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3636074.1"
                     /translation="MKIAYIRVSSIDQNEQRQIEEMKKFGAEKIFIEKQSGATITHRP
                     IFQEALEFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PHLDKFIKDLIIQILAMIAEQERTESKRRQAQVIKIAKANGVYKGRPKLYSADTKNPQ
                     RRLVYENIVKDLNEGIAISKIAKNYNITRQTIYRIKNDIEYNSNQMN"
     gene            1553..1933
                     /locus_tag="ACF3UE_002753"
                     /pseudo
     CDS             1553..1933
                     /locus_tag="ACF3UE_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            1933..2067
                     /locus_tag="ACF3UE_002754"
                     /pseudo
     CDS             1933..2067
                     /locus_tag="ACF3UE_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
BASE COUNT          745 a          306 c          336 g          680 t
ORIGIN      
        1 caatttttag aagaattatc tggagaagaa tatagattat tcctaaataa taatatttta
       61 aaattaatat cttatgccaa gaaagctaat agcctatctt tagtagataa cttagataat
      121 cttttacccg ataaacttat ttatgatgag aatgaagata attcacaaaa acaaataatt
      181 atatttgaat tgtatttaaa gtggcttagc agcctgtcag tgtcaccaga aagcaatgat
      241 gatgataaat attttgcgaa caaactgttt caatttatat ttccagacta ttcttcaatg
      301 ccatttttta cattaataaa ttttatgctg tatgttaaag aacacttagg atatgatgat
      361 ttagtagaaa tgataaaggc atatgataaa gaaccttatc cattcaaagg aatcaatact
      421 ggttcagata tggctatgat ttcaggcgaa actgtagaag aaattctagc taattacaaa
      481 gaacaaaata taaaaactct ggaattaatt aaaaagaata taaaatacta tgatccttta
      541 ctagcgaata aagaaaatat tgataagtta ttaaatgcaa ttgctgattc tgatgttaga
      601 tctcctagaa ttgatgagtt aaaagaagaa attttaatgt ataaagaact tttttaattc
      661 atttgattac tgttatactc aatatcattc ttaattctgt aaatagtttg tctagtaata
      721 ttgtagtttt tagcaatttt tgaaatagct atgccctcat ttaaatcctt aacgatgttt
      781 tcataaacta aacgtcgttg aggatttttt gtatctgcac tatagagttt tggacgacct
      841 ttatagacgc catttgcttt tgcaatttta atgacttgcg cctggcgtcg tttagattcg
      901 gtacgctctt gctctgcaat catggccaaa atttggatga ttaaatcttt aatgaattta
      961 tccaaatgag gattgccaat tgcttcagcc atgatcggta gactggtgat gatcagctgc
     1021 acgtttttct tctttaggta attgactgaa gcaatgattt cgtcgtaatt tcttccaagt
     1081 cggtcgattg cttcgacaat aaaaatatct tggtctcgga caaactctaa agcttcctgg
     1141 aaaatcggtc gatgagtaat cgttgctcca gattgtttct cgatgaaaat tttttctgcg
     1201 ccgaactttt tcatttcttc aatttggcgt tgctcatttt gatcaatcga cgaaactcga
     1261 atataagcaa ttttcaaaat ttttacctac ttcctcaaac tatttaaaat acactcaaaa
     1321 tcaacactaa tttttttata cactataaag ctgtcatttt tctagataaa tggcataaat
     1381 tttcagcgct aagtgacaaa agcaactaat ttttcatgat agatttttaa atatctcaat
     1441 ctatctccaa aattagttgc ttttgtagct atagttgact atgaatatga caaataatta
     1501 gaaaaaactg tgccaattaa atatcaaaat gacaaattga tgaatcaaat tcaaattaag
     1561 gggggcaacc ctggaagtct taaatttacc ctcaatgaat ggtattgaag atgaaaattt
     1621 aaggcgtttg attaatagcc ttgtcattga attgtacaag tatcaagcag aatcagaacg
     1681 aaaaaaaatt aaggaacgtc aggcacaagg aatcgaaatt gctaagaaaa aaggcaaatt
     1741 caaaggtcgg caactgaaat ttaaaaaaaa tgatccacgt ttaaagcatg ctttcgattt
     1801 gtttttgaat ggtttatccg ataaagaagt tgaagaacaa actgggatca atcgccgaac
     1861 gtttagaagg tatcgagcaa gatataacgt gacagtagat caaagaaaaa acaatgaaaa
     1921 gagggatagt taatgagtac ggttatttta gctgaaaaac aagccaggca ttagcctacg
     1981 caagtgcttt aaaacaaagc accaaaaaag acggttattt tgagatcaaa gacccactat
     2041 ttacagatga aacgtttatc acctttg
//
LOCUS       DAXLPC010000173         2033 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.180, whole genome shotgun sequence.
ACCESSION   DAXLPC010000173 DAXLPC010000000
VERSION     DAXLPC010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2033
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.180"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..378
                     /locus_tag="ACF3UE_002755"
     CDS             <1..378
                     /locus_tag="ACF3UE_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFD3636075.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /locus_tag="ACF3UE_002756"
     CDS             426..1826
                     /locus_tag="ACF3UE_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFD3636076.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..2026
                     /locus_tag="ACF3UE_002757"
     CDS             1859..2026
                     /locus_tag="ACF3UE_002757"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636077.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFTGSVAKF"
BASE COUNT          562 a          344 c          437 g          690 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt ttactggttc tgttgcaaag ttttaaatct act
//
LOCUS       DAXLPC010000174         2027 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.181, whole genome shotgun sequence.
ACCESSION   DAXLPC010000174 DAXLPC010000000
VERSION     DAXLPC010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.181"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..582
                     /gene="mobL"
                     /locus_tag="ACF3UE_002758"
     CDS             <1..582
                     /gene="mobL"
                     /locus_tag="ACF3UE_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase MobL"
                     /protein_id="HFD3636078.1"
                     /translation="MNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVL
                     TKEPEYQEYIQISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQD
                     SQIKPLIESVDQMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLR
                     QLNRTINAHEEKYHASKAYEEQQRRIQMEQERQ"
     gene            603..923
                     /locus_tag="ACF3UE_002759"
                     /pseudo
     CDS             603..923
                     /locus_tag="ACF3UE_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1084..>2027)
                     /locus_tag="ACF3UE_002760"
     CDS             complement(1084..>2027)
                     /locus_tag="ACF3UE_002760"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3636079.1"
                     /translation="GPHAGGKHYPKKGFNHIRSKVKMSDVFEFIQSNVHDHDVKQMCT
                     VLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHKILVGRGETL
                     SLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSINQKWVTDITY
                     IHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTPSENLIIHSD
                     LGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYPSKAYENFEA
                     AYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
BASE COUNT          667 a          352 c          423 g          585 t
ORIGIN      
        1 atgaacttat taaatgaagt atataaaacc ctacctgaca aacgttcgga atggaattac
       61 ggggatgaaa aacgaaccaa actttcacca tacacaagag agaaactcga tgagttaacc
      121 aaatatgttt taacaaaaga acctgaatat caagaatata tacagatttc aaaagcattg
      181 aaagaagaag caaaaagtct ttatggggaa agcaagagag aatcaaagga tgcagagaaa
      241 aatgctctct ttgatttaaa aaagcgcaca ggaaatgcca tcctaacaga gctgaagaga
      301 caggatagtc aaataaaacc attaatagaa agtgttgatc agatgcaatc tatttacaat
      361 gaacgatcct ttcgaacgct taaacaattg ccaacgaatg aatacaaata tagttacgaa
      421 gaattcatga agcgcaggaa acaattccaa caaagagttg tcacgcagcg gagtttgcgt
      481 caattaaatc gaacgattaa tgcccatgaa gaaaaatacc acgcaagtaa agcatacgaa
      541 gagcaacaac gaagaattca aatggaacaa gaaagacagt aaagacagta ggaggaatag
      601 caatgaaaca atatttagat caatggaaag ttatagaagg atcattaaga gaagaacgaa
      661 tcgaacaact tcctgattgt ttagaaaaag agcatttgtt ccagataaga gaaatgttga
      721 gaaacgaaca gtttgatcca aatcaatttt tagtcgttga gtacccagct actggtgtgt
      781 attgttgtaa tcatgtgaat ggtgaaaaat attttatcat tcaagaatat gagggcaagt
      841 tagcacctta ttatactact tgggaaatga atgaagaggg aatcaataac tttccatgta
      901 aaagcattgg atttgagtca atacctcgga cacgatttgt gagaattttt tcgagattcc
      961 agcgggtgag tatctcatcg tttcgaccag cggtcaaacc aaaaccgttt gaccgctgat
     1021 cgaagcgatg aagttgaaac cctgtggaaa tctcgccaaa aaaatgtaag tggtagctag
     1081 gaactaagct tgcaatgcca actcctccat ctgatttggt gttaaatagt tgatactact
     1141 atggattcgc ttgcgattgt aaaatccttc aatgtattga aataacgcta aataagcagc
     1201 ttcaaagttt tcatacgctt ttgatggata gacttcttct tttttgagtg aggcgtgaaa
     1261 cgattcgata ccggcattat cgtagggaca gcccttacga ctgaaggagt gccgaatgtt
     1321 caattcattc agctttgcct cataggcttc gctagtgtac tgagaaccca aatctgagtg
     1381 gatgatcaag ttctcggagg gtgtttggtt taagagcgca ttgtcaaggg tttcgataac
     1441 caattctttc gtcatctgct tgccaaactt ccaaccgatg actttctttg tgtggaggtc
     1501 ttgaatagtg gagaggtagg tccagccatc ttttagggta tgaatatagg taatatctgt
     1561 cacccatttt tgattgatcg acgtagtggt aaaatcttgg tttaacaggt ttttacgtcc
     1621 ttcactttta actttcgctt gtttgccagg cttgtacttc ttgagggtga ctgaacgcaa
     1681 gcctaatttt ctcatcagta tttgtacttt ctttaaggac aaggtctcgc cacggccaac
     1741 aagaatctta tgaattttag gcgcaccata gatacccttg ttttcaaagt agattcctga
     1801 aatcaagcgg tttaagcgtt tgttttctga ttggcgcttg gaaggtttct ttttcttcca
     1861 gtcatagtag ctggatttcg gtgcttccaa aacggtacac atttgtttta cgtcatgatc
     1921 atgaacattt gattgaataa attcgaagac atcactcatt tttacttttg agcgaatatg
     1981 gttaaagcct tttttaggat agtgttttcc tcctgcatgc gggccat
//
LOCUS       DAXLPC010000175         2021 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.182, whole genome shotgun sequence.
ACCESSION   DAXLPC010000175 DAXLPC010000000
VERSION     DAXLPC010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.182"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            101..571
                     /locus_tag="ACF3UE_002761"
     CDS             101..571
                     /locus_tag="ACF3UE_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFD3636080.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            793..1896
                     /locus_tag="ACF3UE_002762"
     CDS             793..1896
                     /locus_tag="ACF3UE_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFD3636081.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
BASE COUNT          687 a          328 c          460 g          546 t
ORIGIN      
        1 agaatctctg aagaataaat cacgtgatcg tgacgataaa atacacttac gtcaggtgat
       61 aaaaaataca taagtagaaa actaagagga ggaacagaaa atgaaagaag ttcaattgat
      121 cagaaaaagc gaactatcag aaggtggttg caatgcatgc ggcgtagtag aagcaacaag
      181 ctatacatta aagcttggtg ccaacaaagc gataatctct gagttgacag taggcggtct
      241 tgtggacagt ctggcgcttg ctgaaggttt tattggagaa gatatttatg agatgttttc
      301 agaaatccgt cagttaaaaa aaggggaaaa ctgcatagag gttcatcatg agagcccgaa
      361 tgtgagattc aaacgtggtg ataatgagat gatcttcaat aatcatgtgt ccgatcacac
      421 cgagctatat ggaatcgtga atcaaatact aactgagctt tttggattgg gaccttatgc
      481 gttcaaggaa gaaaacggta atccaaaatt aaacgaagaa tggcaagaaa cgattgaaat
      541 acaaagaaac aacccgcact tatttcaata ggcatccaca gtatttcgta aaagggactt
      601 tgacacgact tttgtcaaaa tcccatcgtt ttttatctat ttgtgttcta aacatttctt
      661 tcagagtagt aacaactgga atgactgaaa tgtaaacaga ttatttgcct gtatcaatac
      721 ggaagagtaa tataaagtgt gtaaacgcta tcatattatt cattcaattt tttatagagg
      781 gaaggcattg aaatggaaaa aacgtatcaa gcaggtacaa atgaaggaat agtggatttt
      841 atcaatatgg aagatttaga aatagccgct tcacaagtga ttccagctgg tggttatggt
      901 tacatcagca gtggtgctgg cgacttattt acttatcaag aaaatgaacg ggcattcaat
      961 catcagctga ttattcctca tgtattaaga gatgtagaat tacccgatac aactacacat
     1021 tttgacaaag aaacgctgac tgcaccaatc atcatggcac cagttgctgc tcatggctta
     1081 gctcatgtga aggcggagaa agcttctgca aaaggtgtag cagattttgg gacgatctat
     1141 acagcaagtt cttacgcttc ttgtacatta gaagagataa gagaagcagg cggggagaaa
     1201 gcaccgcaat ggtttcaatt ttatatgagc aaagatgatg ggatcaattt ggatattctt
     1261 gaagtggcca agcgtaatgg agcaaaagca atcgtattga cagcggatgc aacagttggc
     1321 ggaaaccgtg aaacagaccg cagaaatggg tttaccttcc cactgccaat gccgatcgtt
     1381 caggcttatc aatcaggagt aggccaaacg atggatgctg tgtacaaatc ttccaaacag
     1441 aagcttagtc caaaagatgt agaatttatt gctgctcatt ctgatttgcc agtctatgtg
     1501 aaaggtgtcc agtcagaaga agatgtctat cgttcattag aatctggtgc tggcggaatc
     1561 tgggtatcta atcatggtgg ccgtcaacta gatggtggtc cagcagcgtt tgattcgttg
     1621 caatatgtgg cagaagcagt agataaacgt gtaccaatcg tgtttgacag cggtgtacga
     1681 cgcggacagc atgttttcaa agcaatcgca tcaggtgcag atcttgttgc tattggcaga
     1741 cccgttattt atggattgtc tttaggagga agtacaggag tccatcaagt gtttgatttc
     1801 tttaaaacag aattggaaat ggtcatgcaa ttagctggaa cacaaacagt agaagatatc
     1861 aaaaaaataa aattgcgtga gaatcgtttt atttaagaaa caaatgacga aaaaaatagg
     1921 agtgcggcag atgatgccgt actcctattt ttatagttca aggatgtcac taatagaata
     1981 atttgaaacg aaaaaataaa attgaaatat tttttcatac t
//
LOCUS       DAXLPC010000176         2016 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.183, whole genome shotgun sequence.
ACCESSION   DAXLPC010000176 DAXLPC010000000
VERSION     DAXLPC010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.183"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            364..1524
                     /locus_tag="ACF3UE_002763"
     CDS             364..1524
                     /locus_tag="ACF3UE_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFD3636082.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTIAEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            1540..1983
                     /locus_tag="ACF3UE_002764"
     CDS             1540..1983
                     /locus_tag="ACF3UE_002764"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3636083.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
BASE COUNT          700 a          344 c          390 g          582 t
ORIGIN      
        1 tcttattact caaaacataa cacagttttc acaacctctt ccttaaatgg tgttcaatca
       61 gctgcttctc ggtaataagc tcactagcct agaaaatatg agaagctatt ttctgactag
      121 cactcttatt actcaaagca taacgcagtt ttcacaacct cttccttaaa cggtgttcaa
      181 aagcttgcat ctgcggtaat aagcccaacc caacaaaaaa tatgagtagc tattttttga
      241 ggctgtactt attacttgat gcaggacagc tttttcacaa tctcatcggc tttcattttc
      301 tatttttttc ctgaacccat ataataaaag aaagaacaaa aaaacttgca agggaggaca
      361 catgtgaagc agagtaagca aaaacagtct cgtcgacttt tgtttcgttt gtttttatta
      421 atatgtatcg tcgtagggtt actgatcgct ttatatccat tttatgtgga ttctttaaat
      481 agttttattg atcaaaaacg tatcgaacaa gtacaaaaac ggaccgcagc tgaaattgaa
      541 gtgcagcgaa agaaaatgga ggagaaaaac caacgattaa ctgaccaagg attcaatcct
      601 ggtactgatc ctttcaatga aaagaacaga aatgaaagta caacatccag ccaattagag
      661 gaatggctga tcggaagtat caatatacct aagatccaat taaatatttc actttatgat
      721 cggctcaatg gtaggatcct tgaaaatgga gcaggcgtct tgcaaggaac ctctttcccg
      781 cttggtggaa attcgacgca ttcagtgatc tctgctcaca gcggtttacc taatcgacgg
      841 ttatttaccg aattagatcg tttagaaaac ggagacacgt ttattttgac tgttttggga
      901 gagaaattgg cttatcaagt taaaaatata caagtggtac tgccagatga cacgtctgtt
      961 ctaacgattg cagaaggaga agacttagtt accttgctta catgtacgcc gtatatgatc
     1021 aacacgcatc gtttgctagt gacaggacat cggattcctt ataacgaatc ggtaaaaaaa
     1081 gaagaaggaa aaggaaatca ggaaagaacc atgcggcaat ggtttattct tgcaggaacg
     1141 ataatagctg tagtcatact gttagtgttt atcggacgac taatctatca gtatagatta
     1201 agtaaaaaag tgcttgattt ttcatttatt attagtgatt cgtcagggaa accggtaaat
     1261 ggtagttcat tcattttgaa acataagaaa aaaacactta ctagaaatgg tgtgccgttt
     1321 tcagtacaaa gcgaccatca tgggaaagtc aagctggatc aattgcctgg tgggacttat
     1381 cgaatcgttt cagctgatga tcctaaagtt gctgtttctt ttggtattag aaaagtaaaa
     1441 caagagaaga tatacttttt tgaggggcga aaacttgtaa aagagcttca aaaaaatggt
     1501 ttttatttta aaatcaatga ataagtaagg agagaaaaaa tgatccgcac aacaacaaaa
     1561 ttgtctgcca aagaactgga atctgttcta tcgatttggc tacatgctaa cttggattct
     1621 catgaattca ttccatcaac ttattgggag aatcaagtag aatctgttag gaaagcttta
     1681 ccagatgcag tgatttactt agcagaaata gatcaagaaa ttattggttt tgctggggtg
     1741 attgatcagt ttatcgcagg aatctttgtg aaaagggaat accggcaaca aagaatcggt
     1801 acgcaactaa tgaaaaaaat aaaagaaacc aataaaacac tgactttgac agtctatcaa
     1861 aaaaatcaat cagctattca tttctatctt tcacaaggtt ttacaattca aacacagcaa
     1921 aaagatgaag cagtaaatga ggaggaactt gtgatgaaat ggaatcaaaa cgctgatttt
     1981 tgatgaacag aataacgaaa taatgctccc agccta
//
LOCUS       DAXLPC010000177         1980 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.185, whole genome shotgun sequence.
ACCESSION   DAXLPC010000177 DAXLPC010000000
VERSION     DAXLPC010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.185"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..367
                     /locus_tag="ACF3UE_002765"
     CDS             <1..367
                     /locus_tag="ACF3UE_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFD3636084.1"
                     /translation="KKQIVPKEIETWWRIEMQLRRGKATDWHAMVRESLDSFASPHYL
                     PGDVKPVDRIMIKGLNQDHSEWAYISRNLKYRLRKLLKEESQNDELTNHLRETFKESA
                     NDLKIELDTWLLGLDVTEK"
     gene            1331..>1980
                     /locus_tag="ACF3UE_002766"
     CDS             1331..>1980
                     /locus_tag="ACF3UE_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFD3636085.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVDDK
                     VHPLKLSWSIDRITIVGKLNDTIAYWTQNGVVFVDFEQLMRLNENQGYLKSVGTNGWQ
                     LFDQYGEDIAYIEMLKFHPDKGRIDFNPNKIGEFLKGSMKQFIHDLFLDAHFSRADIA
                     CDILGVPDDFITQYRIVDPVSFKPIYGRSGKLETAYWGSRASERQVRMYNKKLEQER"
BASE COUNT          657 a          305 c          461 g          557 t
ORIGIN      
        1 aaaaaaacag attgtaccaa aagaaatcga aacatggtgg cgtatagaaa tgcagctaag
       61 acgtggcaaa gcaacagatt ggcatgcgat ggttcgggaa agtttagata gctttgcaag
      121 tcctcattac ttgcctggag atgtaaaacc tgttgataga attatgataa aagggctgaa
      181 tcaagatcat tcagagtggg cgtatattag cagaaatttg aaatatagat tgcgcaaatt
      241 gttgaaagaa gaaagccaaa acgatgagtt gacgaatcat ttacgagaga cgtttaagga
      301 atctgcaaac gacttgaaaa tagaattaga cacgtggctt ttgggtttgg acgtgacaga
      361 gaagtgatac cgaataagaa aagtcagatg agtgagagta aatttacgtc aatgtttaat
      421 gacgtgagtt tacgataagc gattattttg cgtgaagcaa aataaagcgt aaaaggagtt
      481 gagagcgtga cacgctttcg gctccttttt tcgttgtcac ttgtgacagc gaataccctc
      541 ggagagcatt tggaattgtg acagccatgt cacaattagg aaaatgttta ctctttgtca
      601 aagagtaaca gaaaggttta cactcttttt attagcgaca gcgcgaagga ggggtttaac
      661 ttggggttta gtatttcgtt caaaaaggga acaaagaata caagcatttc tcataataat
      721 cgtgagttaa ctgatagcca aaaaatcaat ggtttgtctg gtagaaaata attagcagat
      781 ttacaagtgg gaaataaaaa gctgaaagaa gaaaattgca tttcaaacta cattttctac
      841 aatagctcta aaatggcata ttttgcgttc tgagcggttt tagcgtttat ttcgtttagt
      901 tatcggcaca atcgttaaaa cacgttagag gagcgaaaat ggagcctgta aggcgactgg
      961 tagcggaacg atcgtgttag attgtgaaaa ccgatagctg aatgaaataa acagcgggtg
     1021 cgccctttcc atttcggcag gaggaggctc aaggggttcg gggaatgaaa ttccctgagg
     1081 tctttttatt tttttaggag gagtgctata atcaaagaaa acgagaaaaa agagcaaaat
     1141 aaaagccgag cagtgcgcta acactctcga ctatttacgg aaactacttc acctagctcc
     1201 gtaactcagg ttcattatac gaatattttt aggtttcttc aagctagaga tttttggata
     1261 tgaattttta gggttacgtg aactctggaa attctttcca aaagtctctt ttttcgtctg
     1321 gaggacgaaa atggcaaatg aaaatcagtt gagtgaaatt caatcaaaaa ttgaaggtcg
     1381 aggggcagaa aaaagaacaa cgataaatca gctcgaaaaa cttaaccgta tttctaacag
     1441 gcggttaagt gttgacgata aggtacaccc cctaaaatta agttggtcaa tcgatcgaat
     1501 tacaatcgtc ggaaaactga atgataccat agcttattgg acgcaaaatg gagttgtgtt
     1561 tgtcgatttt gagcaattaa tgcgtttgaa tgaaaatcaa gggtatttga agtcggttgg
     1621 tacaaatggt tggcaattat ttgaccaata tggagaagat atcgcctata tcgaaatgtt
     1681 aaaatttcac cctgacaaag gtcgtattga ttttaatcca aataaaattg gcgagttttt
     1741 aaaggggtcg atgaaacaat tcattcatga tttgtttctg gatgcgcatt tctcacgtgc
     1801 agatattgct tgcgatattc tcggtgttcc tgatgatttt attacccagt atcgaatcgt
     1861 tgaccctgtg tcttttaagc caatttatgg ccgttctggc aaattagaaa cagcgtactg
     1921 gggtagtcgt gccagcgagc gacaagtgcg gatgtacaac aaaaagcttg aacaggaacg
//
LOCUS       DAXLPC010000178         1971 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.186, whole genome shotgun sequence.
ACCESSION   DAXLPC010000178 DAXLPC010000000
VERSION     DAXLPC010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1971
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.186"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            192..425
                     /locus_tag="ACF3UE_002767"
     CDS             192..425
                     /locus_tag="ACF3UE_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HFD3636086.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            422..829
                     /locus_tag="ACF3UE_002768"
     CDS             422..829
                     /locus_tag="ACF3UE_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFD3636087.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(1280..1789)
                     /locus_tag="ACF3UE_002769"
     CDS             complement(1280..1789)
                     /locus_tag="ACF3UE_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636088.1"
                     /translation="MKKVLFAVSLVVNIALAGGLFYTITEMNKLDDQRESLAISNEQY
                     KRKLDEASSTNVDTQEAVESSTIVYSNESSETLTNSERSTAPATETVSQKATITIGSK
                     VFTFIVNGLTIEHDSSRTGKMTELSHEFPVIVTTPSATLNGILVQDNNDNNCYIMVDG
                     QTLYRGTYQ"
BASE COUNT          680 a          301 c          326 g          664 t
ORIGIN      
        1 aatttaaaat aaatggtata cataaatagg gaaggaaata gaagggagca atctaaattt
       61 tttgaatttt cttaattaat tatatagaaa gaacaatctt tctatagagt tagacatgag
      121 agggactatg cttgatttaa aatcaacaag cgtatatact gtatatacaa agaaaaagga
      181 gggagaagac tatggcaatt aaagaaagaa aatttaggga agtggggaac tcagtagtat
      241 taactatttc aaaggagttt cttaaagaaa atgggttaaa tcccggagat acggtttttt
      301 tagatgaaga aaaacttcga gcggcaatta caaaaaaaca agccttatct gatgaaattg
      361 atttagcaat atctcaagca ttaactgaat atgatactac ttttagagag cttgtcgata
      421 aatgagtatt cattacctag aagccaaaga tattataaaa atgaatgtaa tccaaataaa
      481 aaaatactct cctaatgaac cccttggtgt aaaggatgcg aatgctttag aaatgtgtgt
      541 agggcaactt cgagcctcag cttttggtga agaggtttat ccttcgattt atgaaaaagc
      601 agctatccta cttatacaat tgataaagaa acatcctttt cacaatgcaa ataaacgtac
      661 tgctttctta gctacttttg tctttttgaa aatcaatgga cagcttttag ctattgatca
      721 aaaagatgct gtaaatttag cggtatatat tgctacgtat gataaggatt tcgatcaact
      781 aaaatatgaa gtgatcaaca ctataaagac acatacgcag cccatttaag gagttactgt
      841 atgtgtcttt atagggttat tagctgctat agcgaaataa ttgaagtaaa ttacaaatag
      901 ctataattca aatccaacta tatagaaaac gtaaattttc tatatacttg gatatgctgg
      961 aatgtttaag agaataatta catttctaga aaatacaata aaaattacag gataattagc
     1021 catatcctac ctcctctagc agttgctcaa aagttagcac taagtaactt cttttttgtt
     1081 gctggtaaca atttatcaat actaaaatag cgtttaagta tctaataaat actaatttta
     1141 aagctcttaa ttattatgaa acacgatata acaatattgc tatatcgtgc tattgtaata
     1201 ttatacattt gaagacagcg tattcttgtt ctaatatcag gaatttttta taaatatcag
     1261 tcatattaag actcaaaatt tattggtatg ttcctctgta tagagtttga ccgtctacca
     1321 ttatatagca attattatca ttgttgtctt gcaccaatat accgttaagg gtagcactag
     1381 gagtagtaac aatcactgga aactcatgag aaagctcggt catttttcct gttctgctag
     1441 aatcgtgttc tattgtcaag ccatttacta taaacgtgaa tactttactt cctattgtta
     1501 tagtagcttt ttgagaaaca gtttctgtag ctggagctgt gcttctttcc gaatttgtta
     1561 gggtttcact ggattcattg ctataaacaa ttgtagagga ttctacggct tcttgagtgt
     1621 ccacgttggt gctgctagct tcatctagct tccttttgta ttgttcgtta ctgattgcta
     1681 agctttcccg ttggtcatca agcttattca tttctgtaat ggtataaaat aatcctcctg
     1741 ctagtgctat attaacaact aaactaaccg caaataatac ctttttcatt cttccttctc
     1801 ttctttctct ttttgtaatt ccttactttt ggataggcta caattaacta gacagaaaaa
     1861 ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct aagagaacac
     1921 gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta g
//
LOCUS       DAXLPC010000179         1919 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.187, whole genome shotgun sequence.
ACCESSION   DAXLPC010000179 DAXLPC010000000
VERSION     DAXLPC010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1919
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.187"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            273..839
                     /gene="amaP"
                     /locus_tag="ACF3UE_002770"
     CDS             273..839
                     /gene="amaP"
                     /locus_tag="ACF3UE_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFD3636089.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            852..1040
                     /locus_tag="ACF3UE_002771"
     CDS             852..1040
                     /locus_tag="ACF3UE_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFD3636090.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1053..1610
                     /locus_tag="ACF3UE_002772"
     CDS             1053..1610
                     /locus_tag="ACF3UE_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3636091.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1642..1884
                     /locus_tag="ACF3UE_002773"
     CDS             1642..1884
                     /locus_tag="ACF3UE_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFD3636092.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          706 a          295 c          395 g          523 t
ORIGIN      
        1 aataaataga atcttgtaat aataactgag cataatcttt gcaattttta atcttgaata
       61 atatccttta agtatagcca gcaatcaaaa gtaaatagag aataagtaag caattgttat
      121 ttcagtatca gactggcaat aaaacgccgt tatgatccag caatgtttgg tagcgcttta
      181 tttactgatg ctatgctaac tgttcgctat ctatactgtg attgtcggta gagttattta
      241 cagggtaaaa ataagtttat aggaggtgga aaatgaataa ggggttaaaa ataatcggtg
      301 ttatcatgag tttactgcta ctttcagtat ttctagcgat tgcgttgatc aatgcgccgt
      361 atattatgcc tgaacaattg gaacgatttc gcttctttac tttaacgaat tactacatgc
      421 aacaatatat tttctgggca gctgtagtat ttgccgttct tgctattatc atcttgctag
      481 tcgttctttt ctatccaaag tcaagaggaa ctttcgttat gaaacgggaa gatggcaaac
      541 taacaatcga caaaaaagcg atcgaagggt tggtacgttc ccatttacac gaagaagagt
      601 tcattcattc acctaaagta cggatacgtt caacgaaaaa tcgaatccat atccatgtca
      661 acggagactt gaaacgaact tcttcattag tagggaaaac aggtgtattg atgcaagata
      721 tcgaagaaga agtaactaaa gtactcggaa caaaagaaac ggtcaaagtg gcagtcacat
      781 acagcggtta tgaagaacaa gaagatacaa gagactacaa gcactctcga gtggaatagg
      841 agggccaaat aatgaaagaa ctattttcag catacaagct ccctattatc tttgggggtc
      901 ttggactact gctagctgtt ttatggttaa cgattggatt tttcaagaca ttgttgatca
      961 taatcatgac agcaattggc gcaggaatcg gtttttattt gaaacagtca ggaatagttg
     1021 atcaattttt taaatcatag gaggaaacaa agatggaaaa caaaaacatg aatacaacaa
     1081 atggatcagt tttggcaaat gaaaaaggag aaaaccgcat gatgaatggt gaattgactt
     1141 atgaagacaa agtcatccaa aaaatcatcg gttatgcatt gaaagatgta gatggtctat
     1201 tgacattaga tggcggattt ttctcaaata tggctgaaaa attagtcaac acagataacg
     1261 taacagcagg tatcaataca gaagtaggta agaaacaagt agctgtggat ctagatgtga
     1321 tcgtagaata cggtaaagac atcgaagata tttacaacca aatcaaagaa ttgatcagta
     1381 ctgaagtaaa caatatgaca catttagatg ttatcgaagt gaatgtgaat gttgcagaca
     1441 tcaaaacaca agaagaatac caaaaagatc aagaaacagt acaagacaaa gtaacagaag
     1501 cagcaaaatc cacaggacaa tttgcttcac gccaaacaga taaagcaaaa tctgctgtag
     1561 gcaaaggtgc acaaaaagtc aaagaaaata acgaaccacg tgtacaataa gaagtaagaa
     1621 gtcagttagg aggaatttaa aatgggattt atttgggcat taatcgtcgg cggtatcatt
     1681 ggagcaattg caggagcaat cacgaataaa ggatcatcaa tggggatcat cgcaaacatc
     1741 attgctggtt tagtaggttc agcaattgga caagctttac taggaacttg gggaccaaca
     1801 attgcaggaa tggctatcat tccatcattg atcggtgcaa tcattttagt attagtcgtt
     1861 tcattctttg cacgtaaatt ataagcaaat tgaagaaaaa cttatgttga aatgaagaa
//
LOCUS       DAXLPC010000180         1914 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.188, whole genome shotgun sequence.
ACCESSION   DAXLPC010000180 DAXLPC010000000
VERSION     DAXLPC010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.188"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            4..396
                     /locus_tag="ACF3UE_002774"
     CDS             4..396
                     /locus_tag="ACF3UE_002774"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3636093.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDDIVYVYDYEKGDK"
     gene            397..1836
                     /locus_tag="ACF3UE_002775"
                     /note="aph(2'')-Ia"
     CDS             397..1836
                     /locus_tag="ACF3UE_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFD3636094.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTDKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCSHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          803 a          138 c          326 g          647 t
ORIGIN      
        1 tttatggaag aagttttaat tgatgataat atggtttttg atattgataa tttaaaagga
       61 tttcttaatg ataccagttc atttgggttt atagctaaag aaaataataa aattatagga
      121 tttgcatatt gctatacact tttaagacct gatggaaaaa caatgtttta tttacactca
      181 ataggaatgt tacctaacta tcaagacaaa ggttatggtt caaaattatt atcttttatt
      241 aaggaatatt ctaaagagat tggttgttct gaaatgtttt taataactga taaaggtaat
      301 cctagagctt gccatgtata tgaaaaatta ggtggtaaaa atgattataa agatgatata
      361 gtatatgtat atgattatga aaaaggtgat aaataaatga atatagttga aaatgaaata
      421 tgtataagaa ctttaataga tgatgatttt cctttgatgt taaaatggtt aactgatgaa
      481 agagtattag aattttatga tggtagagat aaaaaatata cattagaatc attaaaaaaa
      541 cattatacag agccttggga agatgaagtt tttagagtaa ttattgaata taacaatgtt
      601 cctattggat atggacaaat atataaaatg tatgatgagt tatatactga ttatcattat
      661 ccaaaaactg atgagatagt ctatggtatg gatcaattta taggagagcc aaattattgg
      721 agtaaaggaa ttggtacaag atatattaaa ttgatttttg aatttttgaa aaaagaaaga
      781 aatgctaatg cagttatttt agaccctcat aaaaataatc caagagcaat aagggcatac
      841 caaaaatctg gttttagaat tattgaagat ttgccagaac atgaattaca cgagggcaaa
      901 aaagaagatt gttatttaat ggaatataga tatgatgata atgccacaaa tgttaaggca
      961 atgaaatatt taattgagca ttactttgat aatttcaaag tagatagtat tgaaataatc
     1021 ggtagtggtt atgatagtgt ggcatattta gttaataatg aatacatttt taaaacaaaa
     1081 tttagtactg ataagaaaaa aggttatgca aaagaaaaag caatatataa ttttttaaat
     1141 acaaatttag aaactaatgt aaaaattcct aatattgaat attcgtatat tagtgatgaa
     1201 ttatctatac taggttataa agaaattaaa ggaacttttt taacaccaga aatttattct
     1261 actatgtcag aagaagaaca aaatttgtta aaacgagata ttgccagttt tttaagacaa
     1321 atgcacggtt tagattatac agatattagt gaatgtacta ttgataataa acaaaatgta
     1381 ttagaagagt atatattgtt gcgtgaaact atttataatg atttaactga tatagaaaaa
     1441 gattatatag aaagttttat ggaaagacta aatgcaacaa cagtttttga gggtaaaaag
     1501 tgtttatgcc ataatgattt tagttgtagt catctattgt tagatggcaa taatagatta
     1561 actggaataa ttgattttgg agattctgga attatagatg aatattgtga ttttatatac
     1621 ttacttgaag atagtgaaga agaaatagga acaaattttg gagaagatat attaagaatg
     1681 tatggaaata tagatattga gaaagcaaaa gaatatcaag atatagttga agaatattat
     1741 cctattgaaa ctattgttta tggaattaaa aatattaaac aggaatttat cgaaaatggt
     1801 agaaaagaaa tttataaaag gacttataaa gattgattat ataatatatg aaaagctatt
     1861 ataaaagaca ttagtattaa atagtttaaa aaaatgaaaa ataataaagg aagt
//
LOCUS       DAXLPC010000181         1867 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.189, whole genome shotgun sequence.
ACCESSION   DAXLPC010000181 DAXLPC010000000
VERSION     DAXLPC010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1867
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.189"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..471
                     /locus_tag="ACF3UE_002776"
     CDS             <1..471
                     /locus_tag="ACF3UE_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFD3636095.1"
                     /translation="IEKHLAEKDPDNKKIYKENLDKYIEKLNTLDKEAKSKFASIPND
                     KKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKHLVERLRTTKVPSLFVES
                     SVDDRPMKTVSKDTNIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            489..720
                     /locus_tag="ACF3UE_002777"
                     /pseudo
     CDS             489..720
                     /locus_tag="ACF3UE_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
     gene            1598..1867
                     /gene="rpsN"
                     /locus_tag="ACF3UE_002778"
     CDS             1598..1867
                     /gene="rpsN"
                     /locus_tag="ACF3UE_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFD3636096.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAVGDHTDLAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
BASE COUNT          726 a          234 c          317 g          590 t
ORIGIN      
        1 attgaaaaac atttagcgga aaaagatcct gataataaaa aaatctataa agaaaatcta
       61 gataagtata ttgaaaaatt gaatacacta gacaaagaag caaaatctaa atttgcttca
      121 attccgaatg ataaaaaaat gattgttaca agtgaaggat gctttaagta tttctcgaaa
      181 gcgtataatg tgccttctgc ttacatttgg gaaatcaaca ctgaagaaga aggaacgcca
      241 gatcaaatta aacacttagt tgaaagacta cgcacaacaa aagttccttc cttatttgta
      301 gaaagcagtg tggacgatag accgatgaaa acagtatcga aagataccaa tattcctatc
      361 tattcaacga tttttactga ttcaattgca gagaaaggac aagatggtga tagttactac
      421 gcgatgatga aatggaacct ggataaaatt gctgaaggtc tttcaaaata aattggagga
      481 aaaagagtat ggtaaaaatt aaaccaacta ctatactgat ttatttatta gcaattcagg
      541 aattgacgaa aagaaaaaaa gttaaaaaat aaagatttag caaaaattct aagcattact
      601 ccagcatctg taagtgagat gttggctaaa cttagatatg aaggttattt aaacataggg
      661 tgtcaattga caaatagagg gaaagacttt attgacaatt acaaaaagag ctttatataa
      721 aagacttttt atttagaaag gataagaaaa tgactattgg agtaattatg ataggactta
      781 tcctaatagc tggatataat ttttttaaat ctttcttgga ttattttaga aaaggcgaat
      841 gatttagatg agtatattac ttcttatagg attacttttt taatcagcta ttctgttgct
      901 gctcattagt ttaggtttaa gcaatgagtt taataataga cattaatgtt taaaaattta
      961 tagaattaaa aatatcatat aaggcgaatt ttctcatata gactaggtac tacgtgccac
     1021 ttactgaaag ataatagaaa atgaactaag ttattttcaa aaggatgtac ttcatcaaat
     1081 taagatagct ttgtttgtct gaacaatcta tctaaaaaag ataagttcta tcgagatgat
     1141 aggataggct tataattagc ctataaattt ttggaataca gctacaattc tttttcaaat
     1201 tagttactta atgtttattt cttataatat aagaattggt cacaatctta caaaatcatt
     1261 aataaacgag ttaaacataa aagattgaat aaaactatag tttctttcat aatgccgttt
     1321 taagtagaga aaagctactt aaaacggtat ttatgtttta atggactaat aaaaatgaac
     1381 cattattttt tgcacttaaa ctacaagttc ttttaattaa tctgattatc tctatgtatc
     1441 gataaaatca ttttcaaatg gatatctatt catatgattt ttatttcatg ttatttattg
     1501 ttgacaagag aaatttttgt tggtaaagtg tcaatgtcaa aacgtaacgt ttacgatttg
     1561 tgacgtctaa atcaaaacag aaggagtata aatgtatatg gcaaaaaagt ctaaaattgc
     1621 taaagcaaag aaacaaatgg caatgattga aaaatatgca gacaaacgtc aagaattaaa
     1681 agccgtagga gatcacaccg accttgctaa attgccaaga gattcaaatc caaatcgtct
     1741 gaggcttcgt gatcagacgg atggccgtcc aagagggtat atgcggaagt ttggtatgtc
     1801 ccgtattaag tttagagagc ttgcccatca aggtttgatt cctggagtaa aaaaagcaag
     1861 ttggtaa
//
LOCUS       DAXLPC010000182         1851 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.190, whole genome shotgun sequence.
ACCESSION   DAXLPC010000182 DAXLPC010000000
VERSION     DAXLPC010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.190"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            4..1848
                     /locus_tag="ACF3UE_002779"
     CDS             4..1848
                     /locus_tag="ACF3UE_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636097.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT          605 a          340 c          307 g          599 t
ORIGIN      
        1 tttatgtctt tttttaataa catatataat aaaaaagaat ctttttattt acgtataaag
       61 tggagcataa tcattatatt atcattgtta tttttaacag gaattgctta tttcttttat
      121 tttatttttt ctcctgcgga cagcaatcaa atgaaagaaa taaaagattc gtgggttttc
      181 tatacaaaag atgatcctga ttttaagttt gacagcaagt acactcgtac gattcctacc
      241 gtggataaag acgaaacatt cattatggaa acgacacttg aaaaaccgtt ggacgaagca
      301 aatttactaa tcaaaggaaa ccatcaatgg attactgtat atctaggcga aaagatttta
      361 taccaacgga aagattatca ggaagaaagc aatcccggac tctcattggc tgtgatagat
      421 ttaccagcaa attatatcgg aaaaaaattg acccttacag tctcatctcc ttatcagaac
      481 tatgctggac tgccaccgaa agtttatcta ggaacaactg gaccattgat tagttttatt
      541 tattcacaat cagtgccgca agtattgacg atgataatcg ctgtttttat cgctataggg
      601 acctttttct atacgatcta cttgatgtat aaacaaaaac gtcttgaata ctcacttatt
      661 ctcttaagtt gctttgcttt ggcattagga tttgaagctg tatcagaaga tattttaagt
      721 ggtattcttt ttgaaccatt cgttcattct tttttatctc atttatttat tatcttaacg
      781 tcagctttca tcatctgcta ctattggagc cgaatgtttt actataaaaa atggtacgga
      841 attttttgta cgttccaact tttgattttt atcggcgttc tgctttatgc aacttttact
      901 cctgcagaac ttcctgaatt aatgccgatt gctaatattg ctagtgttat aagcacttta
      961 gtcacttcac ttgcatgcat tggcgaagca tataagaata accgttttta tgtagcttgt
     1021 acaccttgga tcgtcttggt agccattatc cattgcttga tttacatcca aacggcatta
     1081 ggtatctatc aaacaacgat caattggtct acgattttat atattatcat tctaatcgtt
     1141 attatcagct acaatctaat cgatcacatc ttaaataccg acaaagatcg gagacaagta
     1201 gatttcttaa aaatcaaaaa tgatttgttg gagcaacatt atgagcagct tcgacagcat
     1261 atccaagaag taaatacact tcgcctggaa tttgtccaag agatggagaa tctgcaagat
     1321 ttaatgcata cggaccaaac aaaagctaaa aactatgtgg aaaagatatt agaagaagca
     1381 aaaaatttcg aaatgctgtg ttctttttgc aaccaccagg tgacaaatct tatcttagcg
     1441 cgttaccaga agttagctgc caaacggaat attcagataa ccttccaagc agatcttccc
     1501 gaagaacttc ctatcaacga tgacgatctg gctcaacttt tgatccacgc tttagagcat
     1561 tcctttagag aaactcatgc catcgaaaat ccactgtatc gaaaaattta tttgtcgata
     1621 cacgaacaag aggaacattt cgtcatttgt tgcgaacata gtgcacatta cgatacaaac
     1681 ctatttagtc gaggcatcac agaagaatta gatgatcagg aacgttttga cttaatgatg
     1741 atgaaagacg tagcggatcg ttacacagga acactaacgc aggaaaaaga tactttcatt
     1801 gatcggatca ctgttcaact ctctcgaaat tacccgaatc ctgtataaaa a
//
LOCUS       DAXLPC010000183         1782 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.191, whole genome shotgun sequence.
ACCESSION   DAXLPC010000183 DAXLPC010000000
VERSION     DAXLPC010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.191"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            339..695
                     /locus_tag="ACF3UE_002780"
     CDS             339..695
                     /locus_tag="ACF3UE_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFD3636098.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            705..1604
                     /locus_tag="ACF3UE_002781"
     CDS             705..1604
                     /locus_tag="ACF3UE_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFD3636099.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT          590 a          300 c          362 g          530 t
ORIGIN      
        1 aagtctttta tttgataagt ttactctacc gaagagttgt taataatccg tgaacaaaaa
       61 gtaattcttt ttccaatagt tgttaaaggt tttttatttt ttatagtatt ttttgttatt
      121 taagaaagga ataaggttaa acaaataaca ggttgctttt tgggtctttt tccgttcaag
      181 aaactgaacg aagaaaaggg aaagttgtct cttttgtgat aagagaaatc ataataaacg
      241 aatgacttac tttccaataa attgagaaca gtcagaacca gacaaattag ttgcatctga
      301 tgaataaagt gattattcta tgacatgagg tgatacagat gaaattagaa gtgacaaaag
      361 aagcacaaga agtattgaag aataaattag aagcagacga tcaactttta ttagatatcg
      421 aaaacggtga cggtccattt gcagaaagcc aagtcagttg ccaattggat acggcatttc
      481 gattgatcat tgtcaaaaaa gatacacaaa cagatctaag tctttattct gtagtggctg
      541 atacaccagt tggaccaatc aaaatcaaag acagtgcaat actttacatg gatgatccat
      601 ccacacttgc tttagaacca acttataata gtttacaatt aaaaggacca agcggcttga
      661 gaaaaggcaa cttgcaagtt gttcgaaaag actagaggga taaaatggga aaattggcga
      721 tcatcagcga cctacatgtg gacatcaata aattcggcga atcagagctg atgcagcttt
      781 ggcaagtttt gcaaaagcac aagatcactc ggcttcatct agccggagat acggctaata
      841 aagtagaccg ttgcctagct gttgtcgaat ttttcgtcaa taaaggatta tctacgacat
      901 ttcatttcgg caatcacgag ttggcagatg tgcccaatga acagatgatg gaccattttc
      961 cagacccaca ttttttaaat gaacggtata ttgctttaaa tgagcagacc gttcttttag
     1021 ggatgaatgg ctggtacgac tatcagtttt ccgaattgaa agattacgag gcaatcgtac
     1081 gaatgaagcg tttgtattgg tatgatcggt tcatccagcg tgggaaaaca gatctcgagg
     1141 tcaatgcaga aatgcttgca gctgcaaaaa atttgctaga ccagctggaa gcaaaaaaac
     1201 ttgaggtgat tttatccact catttcgttc ctaaacgggc atttatcatg tatcaatctg
     1261 ctccttatga gcgttggaac aaattaaatg catttttagg atcagaatca ttcggagaat
     1321 tacttgaccg ttattcaaat atcaaacaag tagtttttgg ccatacgcat cgtcgctttg
     1381 aagataaatc catcggtcac acgatttaca gctgcagacc ttttggttat tattatgaat
     1441 ggcagctgac ccgagatttt gtcttgaaag aacagttgct agacagctat gatcctatga
     1501 aattacgtgt cctcttgcgt gcccatcacc cagcttttca ggcctatcaa acacaacatt
     1561 tgcaagagga atttgaacaa gcgatgacaa tcgttccgta ttgagacagc attagtaatg
     1621 tgtaaaagaa aataccttgt aaaacataag gataagtaag agcagtagat ccatttatcg
     1681 tggatatgct gctttttttg cggaaaataa tcagcgaatg tttatttgat cggatgattt
     1741 gtaactcgca gagtactaga tgcaagcgtg tattcttttt tt
//
LOCUS       DAXLPC010000184         1765 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.192, whole genome shotgun sequence.
ACCESSION   DAXLPC010000184 DAXLPC010000000
VERSION     DAXLPC010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.192"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(430..1002)
                     /locus_tag="ACF3UE_002782"
     CDS             complement(430..1002)
                     /locus_tag="ACF3UE_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3636100.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGIKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1018..1623)
                     /gene="fic"
                     /locus_tag="ACF3UE_002783"
     CDS             complement(1018..1623)
                     /gene="fic"
                     /locus_tag="ACF3UE_002783"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFD3636101.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          517 a          361 c          259 g          628 t
ORIGIN      
        1 taatatcaca ataggaatgc tgtttattat attagcagca gtgctgattt ttatgatagt
       61 tatttggttc ttaaatgaaa gatctaaaga caatcaacac cgtagggata tggagataaa
      121 atcaatagag tcaatagatt atttatcgat aataacacta aaaaagccac gttcctaaac
      181 gtgacttacg ctgaacgata tgtgttgttt ggtagacgaa caaatcgttc attataaata
      241 tatgatggta tcctaatata gtaagcgtgg ctagcatacc tttaattact ttacctttta
      301 cagttaccat acacattttt tgagcagaaa tcaagtaaat aaaaaaatat tatatttcac
      361 aacatgctaa tagactcata tctagaacgc attaagtatt tacctgtctg gttcgctgag
      421 acttcttttt taactttctt caattttctt ctttattcta aaaagcgtac tgcgactgaa
      481 accggttata gcttcaactt ccttatacga tttacctgaa gtaagcagtt catatgcgtg
      541 cctcttcttc ggtgtgattg ttgctttcgg acgtccttct ctgaaattag gattattctt
      601 tcttgcaaac atttttcctt cttgggtacg ttccacaatc atatcacgtt ccatttctgc
      661 tacactcaac aacgtccgtg tcaccattcg ccccatggac gtattttcaa tcgttcctag
      721 attcaaaacc ttgatcgtta cgttatcatc gagtaaaggt tcaatgatct ctaatgcttc
      781 tctcgtgtta cgagcaaatc gatcaagctt cgtaacaact atttcatctc caggcttcag
      841 accagccaac agctgattga attttggccg atcccgtttt atacccgtaa atttttctga
      901 aaaaatattc ttcttctcta cgccgttctc aagcaactgt tgaatttgtt cttttgtact
      961 ttgagaagcg gttgagacac gtgcatatcc atatttcgtc atttggtcca cctactttta
     1021 caaatcatct atcgtatact cagaataccc ttcatagaaa tagctgacat cgattccttt
     1081 catatataac tcgcgatcgt caattttatc agtcagagca ttggaaatta gatagcgtat
     1141 ttccaaatcg tttatgggac ttcgctccat tgcagaaaga tagtctgctt tatcgattaa
     1201 gttccaatct acaacttttt gcaattcttc ctttaaaatg agatccagcc aaattctagt
     1261 acttcggcca tttccttctc gaaatgggtg agcgatattc atctccacat atttcttgat
     1321 aatctcttca aaagaagttt gtggcatctg atcaatatgc tgtaacgaat gttctaaata
     1381 cataactggt gcaaatcgaa aatttccttt tgcaatattg accgatcgga tttttccggc
     1441 aaaatcgtaa atatccgaaa atagaaattc atgaatttca gataaacctt taaatgtacc
     1501 aacttcgatt tcatttattt ttccacaatc gtacaattct ttcgcttttt gtttactgag
     1561 tttttcttca accttagcca actcaacttg attggttaat cccaatttat tctctaaaat
     1621 catgcgaaat ctccttaact ttatgacata agtttatgaa acactctcaa ccccattata
     1681 tcgcgatttt gtttatgtgt caaaaactat taagtttctg acccccgata gatttttcaa
     1741 gtgtctctat tttgcacagt ctagt
//
LOCUS       DAXLPC010000185         1742 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.193, whole genome shotgun sequence.
ACCESSION   DAXLPC010000185 DAXLPC010000000
VERSION     DAXLPC010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.193"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(26..337)
                     /locus_tag="ACF3UE_002784"
     CDS             complement(26..337)
                     /locus_tag="ACF3UE_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3636102.1"
                     /translation="MSKNNNKNNSSELENCLFNPKKLEDSINKVKRINDLPLVLTNKD
                     LKEQFQISDSTLNRLIKLDNFPRCWFGIKGHYLRDDILEWIKKGKEEYFCDQFRLLRE
                     L"
     gene            complement(689..934)
                     /locus_tag="ACF3UE_002785"
     CDS             complement(689..934)
                     /locus_tag="ACF3UE_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3636103.1"
                     /translation="MVDKPKKWQYPLVPLSIILSALEEDPISIKMILKHYDNYIAKLC
                     LTNGFNEVGQFITYVDEYMLRQLEVKLIEAILKFKVN"
     gene            complement(928..1329)
                     /locus_tag="ACF3UE_002786"
     CDS             complement(928..1329)
                     /locus_tag="ACF3UE_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HFD3636104.1"
                     /translation="MQQNYNEKSIQHQFDAYCKKVLRNEAKSIRKRNTRIKDNEEPLN
                     DVNEGKYPQTNFDEQDVYFLFGMEILISDQKLSAAIDQLSDIRRKIILLYYFADFNDA
                     EIGRILNMSTSGIWYQRTKAVEQLKMGYDLW"
     gene            complement(1566..>1742)
                     /locus_tag="ACF3UE_002787"
     CDS             complement(1566..>1742)
                     /locus_tag="ACF3UE_002787"
                     /inference="COORDINATES: protein motif:HMM:NF012948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3636105.1"
                     /translation="TTQVGKQAKKAKMLPKTGEEDTNMITIFGGLLLLGSLGLIDYKK
                     RESKKSSSRIERSK"
BASE COUNT          547 a          311 c          221 g          663 t
ORIGIN      
        1 caatatacag acgaaaaaat aaattctaca attctcgtaa taaacgaaac tgatcacaaa
       61 agtattcttc ctttcctttt tttatccact ccaaaatatc atctctaagg taatgccctt
      121 tgatgccaaa ccagcatctt ggaaaattat ctagttttat aagacgattt aaagtactat
      181 cacttatttg aaattgttct tttagatctt tatttgttaa aactaacggt aggtcattta
      241 ttctctttac tttattgata gaatcctcta gctttttggg attaaataaa caattttcta
      301 actctgatga attattttta ttgttattct ttgacatgat tatctcttcc cttctattat
      361 taaggattaa tctatcagct gcctttgtca aaagcacata ggaatttcac ctctccccaa
      421 gtttacggcg agccttacgg aagtatcatt atcccaacct caaatcatcg ctttttattg
      481 actataaaaa ttattttaga atatttatcg ctccttcttt ataataagag atcatggcgt
      541 aactaaaata tgctccttga agtgttaacg tactgataga atatatttat ttttcaatga
      601 acaataggtt ttctccctaa aagaatccgc taatctaaag tattagaaga ctctttttgg
      661 tagaaaaagt agaaagggga gtttttagct agttaacttt aaatttcaat atagcttcta
      721 ttaatttaac ttctaattgc cttagcatat attcatccac ataggtaata aattgcccca
      781 cctcattaaa tccatttgtt aaacataact tagctatata attatcataa tgtttgagta
      841 tcatcttgat cgaaattgga tcttcttcta gagcagatag gataatagat agtggaacta
      901 atggatactg ccattttttg ggtttatcta ccataggtca taccccattt tcaattgttc
      961 aactgccttc gttcgttgat accagatacc acttgtactc atattgagaa ttctaccgat
     1021 ttcagcatca ttaaaatcgg caaaataata aagtagaata atcttccttc ttatatccga
     1081 taactgatca attgctgctg ataacttctg atctgaaatt aatatctcca ttccaaataa
     1141 gaaatagaca tcttgttcat caaaattagt ttgtggatac ttcccttcat ttacatcatt
     1201 cagtggttcc tcattatctt ttattctagt gtttcgtttt cgaatagact tagcttcgtt
     1261 tcgtaatact tttttgcagt aggcatcaaa ttggtgttgt atagatttct cattatagtt
     1321 ttgttgcacg atcaatatgc tcctttatcc cctttccact aatacaacaa tcagagagtg
     1381 cctttttttc gaaaaaacta aaaaaaaaca aaaaataatc atacttttta ggtggaattt
     1441 cattctcaaa aaaaaaaaaa acgattagta tcactaatcg tttttgagta ttccttgcaa
     1501 aagccaaatt acttttatag ttaaaatttg atattgataa tcatccttct ttcggtagtg
     1561 ggtaatcatt ttgatctttc tattctactt gatgattttt tagactctct ctttttataa
     1621 tcaattaggc ctaaacttcc caacaataga agaccaccaa agatagtaat catatttgta
     1681 tcctcttcac ctgttttggg taacattttc gcttttttag cttgtttccc tacttgtgta
     1741 gt
//
LOCUS       DAXLPC010000186         1728 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.194, whole genome shotgun sequence.
ACCESSION   DAXLPC010000186 DAXLPC010000000
VERSION     DAXLPC010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.194"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            245..1210
                     /locus_tag="ACF3UE_002788"
     CDS             245..1210
                     /locus_tag="ACF3UE_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFD3636106.1"
                     /translation="MAVVLTVAANKGGVGKTLITINLAGAIRRSFPEAKILVVDTDAQ
                     GNSTKSFRVKVAKDQNTIYDVFMDNATVEETIVQTYDDHIDVLPANSDNNYLEFDKME
                     QFRDTILEWFVSLLKKFKDNLTEIMTVSGLKKKMNNIIDPSANYFNALDGKFDNVSDK
                     YDYIIFDTPPELKQVTSSVLSIADVVIVPYEPDLNGVDGVTHLISRVNTLKEKYNPNL
                     RIGGVLANKVYNTNLHAKMINAMMKYTNRNNYHYFDSELPRSITFADKLVRNGMPITM
                     SSPENKFAQHFYKLIIEMNKLGLLSKNGKELEIPHKLYVESDGEE"
     gene            1210..1674
                     /locus_tag="ACF3UE_002789"
     CDS             1210..1674
                     /locus_tag="ACF3UE_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636107.1"
                     /translation="MPRINRKKPTGDFESVFDEELEELETPNDTIDSIPETEVTVSNS
                     FPSDKETITENFNEANRFGLSKTSKSTSSELVARTFKYKKETIQRVESLVYKDQRHSK
                     KIPGTKGFISDFMDNAIWQHLLQLGLATEEEVQKHLNSYSKYPLNFDNYEKK"
BASE COUNT          637 a          253 c          280 g          558 t
ORIGIN      
        1 tataatatat tatcttacta ttatgttact attatcaata gtaacataat ataaaatctg
       61 ctgttttatt ttttgattta ttgttgattt cgacaacgta ttatgctaat atgagaaagt
      121 aatatagtat attactttct cgtattgtta cgattaacaa aatattactt tatatattat
      181 tatctatatt acttatctat taccaaaaat attactatta tattatttag ggaggaattg
      241 aaaaatggca gtagttttga ctgttgcagc aaacaagggt ggtgttggta aaactcttat
      301 tacaatcaat ctcgcaggag ctatccgtag gagttttcct gaagcaaaaa ttcttgtcgt
      361 tgatactgac gctcaaggaa atagtacaaa gtcttttcgt gtgaaagtag ctaaggatca
      421 aaatacgatt tatgatgtct tcatggataa tgcaacagtt gaagaaacta ttgttcaaac
      481 atatgacgat catatagacg ttcttcctgc gaattctgat aacaactatt tagagtttga
      541 taaaatggaa caatttcgtg ataccatatt agaatggttt gtatctttac ttaaaaaatt
      601 taaggataac ttaactgaaa tcatgactgt ttcaggatta aagaaaaaaa tgaataatat
      661 tattgatccc agcgcgaact attttaatgc tcttgatggt aaatttgata atgtgagtga
      721 taaatacgat tacatcattt tcgatacacc accagagtta aaacaagtta cctcatctgt
      781 tctttcaatt gcagacgtag ttatcgtccc ttatgaacct gatttaaatg gggttgatgg
      841 agttacacac ttaatatctc gtgtgaacac attgaaagaa aaatacaatc caaatttacg
      901 cattggaggc gtacttgcca acaaagtcta taatacaaat ctacatgcaa aaatgattaa
      961 cgcaatgatg aaatatacta atagaaacaa ttatcattat tttgattctg aactcccaag
     1021 atcaattacc tttgctgata aattagttcg aaacggaatg ccgataacaa tgagttcacc
     1081 tgaaaacaaa tttgctcagc atttttataa gctgattatc gaaatgaaca agttaggttt
     1141 actttctaaa aatggtaaag aactagaaat tcctcataag ttatatgttg aaagtgacgg
     1201 tgaagaataa tgccaagaat aaacagaaaa aaaccaacag gagattttga gtctgtattc
     1261 gatgaggagc tggaagaact agaaacacct aatgacacta tcgatagcat acctgagact
     1321 gaggtaactg ttagcaatag ttttccctca gataaagaaa caattaccga aaactttaat
     1381 gaagcaaaca gatttggctt aagcaaaact tcgaaatcta caagttctga actagttgca
     1441 cgtacattta aatataaaaa agaaactata cagcgagttg aaagtttagt gtacaaagac
     1501 caaagacatt ctaaaaaaat tcctgggact aagggattta tttcagattt tatggacaat
     1561 gcaatttggc aacatttatt acagctggga cttgccactg aagaagaagt tcaaaaacat
     1621 ctaaacagct atagtaagta tccacttaac ttcgataatt atgaaaagaa gtagcttatc
     1681 gctatttctt tttttatagg gcgaaatttt tatatcacta tttgtatt
//
LOCUS       DAXLPC010000187         1699 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.195, whole genome shotgun sequence.
ACCESSION   DAXLPC010000187 DAXLPC010000000
VERSION     DAXLPC010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.195"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            239..919
                     /locus_tag="ACF3UE_002790"
                     /pseudo
     CDS             239..919
                     /locus_tag="ACF3UE_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
BASE COUNT          607 a          241 c          292 g          559 t
ORIGIN      
        1 tttaaacggt agttacttag ttcttctttg atttgcgtga aatagagggg atttattttt
       61 ctggttacgt gattaaaaaa tccaaaaaat gagcatagga acggttatga ttttagggtg
      121 tgttttaatg agatattgtg atttcattaa caagtgtatg ataatcggtt cttttgcaaa
      181 gttttccaaa aaatctattt tagtgtaaaa ttgagaaaaa aacagagagg acagagtaat
      241 gaatcatttt aaaggcaaac aattcaaaaa agacgtcatt attgtcgctg ttggttacta
      301 cctgcgttac aatctaagct atcgtgaagt tcaggaattg ttatatgatc gtggaataaa
      361 tgtttgtcat actacgattt atcgttgggt gcaagagtac agcaaagtcc tctattatct
      421 ttggaagaag aaaaatagac aatccttcta ttcatggaaa atggacgaaa cctatatcaa
      481 aattaaggga cgttggcatt atctttatcg tgcaattgat gcggacggct taaccttaga
      541 tatctggtta cgaaagaaac gggatacgca agcagcctat gctttcttaa aacgactcca
      601 taaacagttt ggtgagccga aagcaattgt gaccgataaa gcaccttctc ttggctccgc
      661 ctttagaaag ttacagagtg tgggtttata tactaagaca gagcaccgaa ctgtgaagta
      721 tatgaacaat ttaatagaac aagaccatcg acctattaaa cgacgaaata aattttatca
      781 aagtctccgt acagcctctt ccacgattaa gggcatggag accattcgag gaatatataa
      841 aaagaactga agaaatggaa cgctcttcgg cttttcggtg tctactgaaa tcaaggtatt
      901 aatgggaata acagcctaag atatttggag ttcagagagg gcgcgtttga ttttcaaact
      961 tcgcaacaga acccattagc aatatataaa agaaggtatc aagagtcaca gtgaatttat
     1021 tccgaaaagt gaaaagagca aatataaaat ttaataaaaa taagaactaa ataggaaaac
     1081 gtagacgtaa ttttctacgt tttccttttc atatatatta aatattacgg aaaattatat
     1141 aaactaattt agtgttttgt ttgtaattcc taattttgct ccacttttag ataattttta
     1201 ggtctattta actcattaga cattctatgc tcatttttct ccaaatttgt ttcaactctt
     1261 tcgtacttaa ttttgcgtat ttgaaaattc ttcttttaga gtacttttat tacgatacta
     1321 gtatgatata tatctacagc aaacagttaa aatcttccta aaataagcga atagcattcc
     1381 taaaacctat aaaattttta gatgaagcga caagtggaca attaataaac tacttgaaca
     1441 tgaaattatg gatcaccttt caaatttaga aaatggaatt cttatactta ttgcgcaaca
     1501 tttattgatt gcaaaattat gtgacaaaaa gaactagtag aagaaggaat aatggcttga
     1561 taataaagta ctacctatta aaggtagtac tttatttaat ttagtataaa ttaacatact
     1621 actatatttt aggtttcata ttatataaat taataatata ctaccatttg ttggtagtat
     1681 aatttaaagg taataagtt
//
LOCUS       DAXLPC010000188         1621 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.196, whole genome shotgun sequence.
ACCESSION   DAXLPC010000188 DAXLPC010000000
VERSION     DAXLPC010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.196"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(606..1220)
                     /locus_tag="ACF3UE_002791"
     CDS             complement(606..1220)
                     /locus_tag="ACF3UE_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFD3636108.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT          521 a          299 c          253 g          548 t
ORIGIN      
        1 ttatattaag tattttattt ctctgttttt ccttaaaatt ctttttttat ttttagatta
       61 gagaaaatct cgtcctgttt ttttcatttt acaatcattg aaaaattgaa tttcattgca
      121 aaaaaaataa taaacactta taaatatcca ttatctatcc ttcaattttt gtgtatttta
      181 tttctattag aaaaaggtat cctgttggac aattttgtta tatcaggtaa acttcattgc
      241 aataatgata acaaatgtac tataattact ttgtaaagag ttttggggaa gactctttca
      301 tcaacgtgta ttaagagaca agaaagaatc catatggatt ctttcttgtc tctttttcca
      361 ctacttttta tttttctgac actacatatt cttataactc atttctcata actgtgaaac
      421 aacttataaa aataacaaac tttaaacaaa acaagcttaa aatcaaagat gatccatctt
      481 aaaataacta aaacaaaaaa agtagtcgtt gttaatcctc attaataatc gttttctttt
      541 tttcaaacgc tccattttta tgtggaacat tattttttta aggaactttg tcaacatgtg
      601 gataactatt ttccacttgt gtcctggact agctgttttg ctgtaaaata caaaacttgc
      661 tgcagcaaaa agatcgttgc aagagaggct gttccgcaga tcgctggatc tagatttggc
      721 aaagtcaaga ctgcatcatg taaattggcg tggttgtcca aaaccaaatc agcaaattca
      781 aataatcgca aaccactgct atgttgcgat ttgatacttc gtgacaaatc aaatccagta
      841 acaatgatta atggatgacc attttctttg atccactgag ctagttcgat gattgccggg
      901 tttcttcctt cattcgaaag aagaagaaaa atgtcttctg atttgacaga aagctgatca
      961 ataattgcct gtcctgcacc ttctagcgtt tcatagacac ctccggctgg attttcaatc
     1021 aatatacttg gtacaagatc cggggtttga tcccaaaatt caaatgctac accacttagt
     1081 gtgcggctag catatatctg caatctacca ccttgattaa tttgtttcgc gatccaagtg
     1141 ccagcttgaa gcatcagcgg ctcttctatc cttaatttct cttccaattg gtgataatag
     1201 tcaaaataac ataaactcat ttatctctcc cgcctagcta tacttgacat gaatagaaac
     1261 agctgcctaa tctaaggaag tacataaaaa aacagtagtt agacagtaac acatgtggtc
     1321 tttgctgttt caaacacaaa aaaggcattg aacgaatacg cccaatacct tgacatagca
     1381 aataaaacaa cgtgcagacc atggaaaata tctacatagg ggtagaattt tcaccctaga
     1441 ttaggtacaa taaattaggt cgatgcactg cattgactat ggcaaaatga tcggtcaggg
     1501 tgtatgtgtg tgactggtca ttccctgatt cttagcgcca actaagggtc agggagcctt
     1561 tttttattca gctgtttcta tctgaattta ttgtaagtaa tctcttatcc aagtgcaagc
     1621 a
//
LOCUS       DAXLPC010000189         1588 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.197, whole genome shotgun sequence.
ACCESSION   DAXLPC010000189 DAXLPC010000000
VERSION     DAXLPC010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.197"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..200)
                     /locus_tag="ACF3UE_002792"
     CDS             complement(<1..200)
                     /locus_tag="ACF3UE_002792"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3636109.1"
                     /translation="MTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKEGISVSL
                     KHVQKLMKQLNLRSIVVKKYRP"
     gene            complement(311..565)
                     /locus_tag="ACF3UE_002793"
     CDS             complement(311..565)
                     /locus_tag="ACF3UE_002793"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3636110.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
     gene            complement(645..998)
                     /locus_tag="ACF3UE_002794"
                     /pseudo
     CDS             complement(645..998)
                     /locus_tag="ACF3UE_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1111..1368)
                     /locus_tag="ACF3UE_002795"
     CDS             complement(1111..1368)
                     /locus_tag="ACF3UE_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636111.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
BASE COUNT          482 a          324 c          211 g          571 t
ORIGIN      
        1 tgaggtctat attttttaac tacaatcgac cttaaattta attgtttcat tagcttttgg
       61 acatgtttaa gagatactga aatcccttct tttaataaaa cttgatggat ctttgtggca
      121 ccatagcgtt gtttattcgt aaaaaaaatt gttgaaatct tctttttcaa cttattattt
      181 ctgatttctg tagctgtcaa cggtttattc ttataaaaat aatagacact tctagggatt
      241 tctaataacc gacacaacaa agaaacagtg taatccttac accatttttc aataaattga
      301 acaagcgaat ttaggttttc cgagagaata tggctgcggc tttttttaag atttcaagtt
      361 cctcatttaa acgagcattt tcttttctca gttcagctac ttcttttcca gtcagtcctg
      421 tggactgatc aggtaaatat aaattcttcc atttgtaaat cgttgcttca gataagccat
      481 attctttcgc taaccctcga acagaacgtc cagtttgatt cagttcaaca atcatttgtt
      541 taaaattttc ttcatatcgg gtcataaaaa ttcatcctct cgtagataag tttaatttat
      601 tcttgtctct acgaaaagct gtctaagatt tgatactaac accaatcgtc cccaaaaggt
      661 agatcttctc taccactagc taatctactt ctccatcttc gttctctttt catagaacct
      721 gcgctgaact cacacccgtt aaactcagct atgacagtat cttcaattat gttaatctgt
      781 ccatctagtt cgtattcaat cctaaatgga aattctccat aggtgatttc cggttcgggt
      841 attttaggtg agattaatgc aaagaaagga aatattaagc ttggcaacat caaaaaaact
      901 cctcctatga tcacaattcc cgatgtaatc caaaatataa tttgtacaat tctcattgat
      961 ccattgtatt ccattttatt ccccctatta ctattcatat ccgcctatct atatcgatct
     1021 tccaatgcag agataattgc ttccatacct tgatttttta ctgagttacc tatgcgagat
     1081 atcattctcc actaaggtgc atcatattgt ctatctaaca tgattaattc tccaataggt
     1141 gtatactcct ccaaaaacaa catttaatgc atctccctcg acaacataag ctaccatgtt
     1201 tgctgtatat gtgtttgagt ctaattcata agcagataaa tttactgtcg ctggattaaa
     1261 tataatcgca ttcgtattta tagctactga atttgctgct tcagcaccac cttttgaatg
     1321 tccgatcatt gtgatttcaa tagtaggatt tacgtggaca gccctcaccg tttaccctga
     1381 ccattataga aatcgcttac ttttttgaac tacgcaacaa aggatacaat gctcctaact
     1441 tcactgtctc catttttgtc cactaaggaa tataaaaaat aggcattaat tcatttaatt
     1501 cggtcacaac acgttacctt ttaaatcatt atactgtatc tcatacatta ttatcaataa
     1561 actattataa aaatgcaaaa aatgcttt
//
LOCUS       DAXLPC010000190         1570 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.198, whole genome shotgun sequence.
ACCESSION   DAXLPC010000190 DAXLPC010000000
VERSION     DAXLPC010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.198"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            182..877
                     /locus_tag="ACF3UE_002796"
     CDS             182..877
                     /locus_tag="ACF3UE_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFD3636112.1"
                     /translation="MRSSKYTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVL
                     KGIEIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFA
                     QLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKS
                     AYLYDNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKAKGVTELAI
                     YQKRKRIMVPLPV"
     gene            complement(914..1411)
                     /locus_tag="ACF3UE_002797"
     CDS             complement(914..1411)
                     /locus_tag="ACF3UE_002797"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3636113.1"
                     /translation="MNNQIALAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
     gene            complement(1467..>1570)
                     /locus_tag="ACF3UE_002798"
     CDS             complement(1467..>1570)
                     /locus_tag="ACF3UE_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFD3636114.1"
                     /translation="LESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT          501 a          283 c          254 g          532 t
ORIGIN      
        1 cacacacaat tttttaaggt cttaaaacca tcatatatgc aaaagaagct aacctttatt
       61 actaaattag acccgtggtg ctagttaatt ttttcctaga ggaaaatgtc taaacatgtt
      121 ggtaaatcaa caaaaaaacg catatagtag tctcaaaact cccaagaaat gaggactaca
      181 tatgcgttca tcaaaatata ctgaacattt tgacttagcc aatcctgtta ctaaagtcga
      241 tgatatcccc gattatgaaa tgtacagtca aacaatcgat agcttaaata agcgttttgg
      301 caatcgtgtt ttaaaaggca tagaaatcgg ttacatcgct tctgaaaagg atcggatcat
      361 cgactattta gccgataaag attacgattt aaaattactc agtgtgcatc ataatggtca
      421 atttgattat ttagatgacg aagtcaaaga tatggatcct gctattgtga ttcctcagta
      481 ttttgcacaa ctttcagaag cactagttgt tatagaagca gatgtctttg ctcattttga
      541 ctatggtttt cgggtatttg gtctatccgt tgctgaattt aaacaatatg aagcgcagtt
      601 tttaccgatt ctagatcaag taatcaaaaa taaattggca ttcgaattaa atgctaagag
      661 cgcttacttg tatgacaatt tagcgttata tgaatatgtc atcgatttat atctttcacg
      721 tggtggtacc ttgtttagtg ttggatcaga tgggcattac cttgaacatt tccgtttcca
      781 tttcgatgat ctttttgctc tgttaaaagc aaaaggtgtg acggaattag cgatttatca
      841 aaaaagaaag cgaattatgg ttccattacc agtctaaaaa aacgtcctca gcatcaaaag
      901 tgaggacgtt tttttagatt tctttttcta aaatcggaca aatacgatct tgttttccta
      961 aaggaaaatg tttgatcccg atttttttaa atccatgacg ttcataaaaa cgaatacctg
     1021 catgattttt ttcataaaca gtcaaacgta aataacgttt ttgtttcgtt ttagcataac
     1081 gattcgcttc atcgagtaac cgttgcccta accctttgtt ttgataatct ttgagcagat
     1141 agagccgttg aatctctata gcatcttttt catcattgac tttcatataa ccaatgagta
     1201 tttgatgatc cttaatacca ataaatttac tggttgactg tgccaattct actgccaata
     1261 tttcagttgt caattgtgtc tgtaaatatc cttgcatatc aagtggatct gcgccatcga
     1321 taaacgattc ataaaaactg acaacactta caacttgtaa agcatctaga tcatcataat
     1381 ctaaatacgc tagtgcgatt tgattgttca tctaactcct ccttttgaca tagtatacta
     1441 taaatcaccc gtggtgctag ttaattttaa tatcctaaag aatatctcaa agttccttca
     1501 aaacgtcgtt gtgctcgact taatagaaca ctgtaagcca gtaatatgct ttcaaatcta
     1561 ctctctagcc
//
LOCUS       DAXLPC010000191         1487 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.199, whole genome shotgun sequence.
ACCESSION   DAXLPC010000191 DAXLPC010000000
VERSION     DAXLPC010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.199"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            275..>1487
                     /locus_tag="ACF3UE_002799"
     CDS             275..>1487
                     /locus_tag="ACF3UE_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFD3636115.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     ETILEFNDSYHFDQIVIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFS
                     RMFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQH
                     FLENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGK
                     GRFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQ
                     VIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQ
                     SQNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARK
                     FTRLVDTLLRKH"
BASE COUNT          486 a          293 c          270 g          438 t
ORIGIN      
        1 atgtatggaa aggatccaac gggaatttgc tatttcctcc tgtagcgttt gtctaccctg
       61 tttagtctgt tacccgaacc actgttatca ctaccaactc attagctgtt tcgataatgg
      121 actagacttt caaatagtag tttggaaggc agcttctagc tcttttatca ccgtattcta
      181 ttaggcgagg ttgtggctat acagtgagtt tctgggaaat cccacagtat cgaagcattt
      241 tccaaaattt atatcgaaag gaggtccttc ttccatgaaa ttatttgtcg gtattgacgt
      301 tagctctgaa aaactagatg tttgtttttt aacagacgac aatcaattgt ctatcttatc
      361 tgaaatctct gttgccaatg acatcgaagg tgcttcattc atacgagaaa caattcttga
      421 attcaatgac agctaccact ttgatcaaat tgtgattggc atggagtcaa cgtccatgta
      481 cagcttccat ccttccatgt tttttcatga agatgagaaa ctaaagaagc tcaacacact
      541 tgtaacgatt gaaaatcctt ttcgggtgaa acaatttagt cgcatgtttg atgagaataa
      601 aactgatcga aacgatgcat taagaatcgc tgatttcttg cgtattcaac gattcacaac
      661 ttcccctatc aaagaagaga aatacatggc cttacagcgt ttaacacgta ctcgctatca
      721 acttattaag caattgattc gtacaaagca acattttctt gaaaatctaa cgtacaaatg
      781 taatacgctt gctcgagaaa tgcgagacga atcgacgagt ctttttagtg caaccctcat
      841 ttcactcatg acggaagatt tcacattgga tgaacttgct gagcttcctt tagaagcttt
      901 ctgtgattta cttcaagaaa aaggaaaagg ccgtttcaag caaccagaaa aaatcgctaa
      961 agcaattcaa cgtgcaatta ccatgagtta ccgcctaggt gctcttgcac aagaatcaat
     1021 taatgttgtt ttaagtgttc tcgtacgaga aatacgagca cttgaaaaaa atatcaaaga
     1081 attagataaa gccatcgaac aagtaattgt tgtcattcca gaatatcaat gcttaaccag
     1141 tattccaggc gttggtaaag tctatgctgc cggtttaatc gctgaaattg gtcaaatcga
     1201 aagatttgaa gatcagacaa aattggcaaa atacgctgga ttaagttgga aagtgaacca
     1261 atctggaaac tatcagtcgc aaaatacacc tctgacaaaa caaggaaatc gatattttag
     1321 atactactta gttgaagctg ccaactctgt aaaaaattat cttcctgaat acaaagcttt
     1381 ttatcaaagt aaatataagg aggttccaaa gcatcaacac aaacgtgcac tcgtcctaac
     1441 cgcaagaaaa tttacgcgtc tggtggatac gctactacgt aaacacc
//
LOCUS       DAXLPC010000192         1485 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.200, whole genome shotgun sequence.
ACCESSION   DAXLPC010000192 DAXLPC010000000
VERSION     DAXLPC010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.200"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            850..>1485
                     /locus_tag="ACF3UE_002800"
     CDS             850..>1485
                     /locus_tag="ACF3UE_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HFD3636116.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFS"
BASE COUNT          490 a          245 c          250 g          500 t
ORIGIN      
        1 cgaaccgcca caagccacca aataaattcc agaaatctct ccatcatttt tttctacaat
       61 tgcgttaacc gtttttgcta catccatcaa catttcctcc ttaaaatttt aaaaatgtta
      121 attttatcca aaataaaagt aactgattaa atgtaaagat atcacataac gtcatataac
      181 gtcatgtgac ataattgcat tgtatccgct ttctttgtgt ttgtcaatag gaaaaattta
      241 tttctctaaa aaatataaat aatctgcagt gaaacttgag tacatatact aatttcgaaa
      301 aatgcctatg atttaaataa ttatggtgct gggatgaagg tttataagtt tgtcttgatt
      361 tgtttagaag aaatcgtttt tgcacacagt tgaattagga aactactgga gtggaaaata
      421 aagtgatttg acgggtagat gggtgcactt aaatttgaaa atggcttaaa atgctttatt
      481 ttgaattgca gaatttcttt tagtacgcaa tttatggtct taaaactgat taaaaagtga
      541 tacattgatt ttaatacaat ttatgataca aaaaatgacc tcctttctta aataaaagag
      601 gtcattttgt tttgtctcat aatcgattgt ttttgataca gtagttatat tcagaaaaaa
      661 taaagactct tctgagttta taatcctttg gattatatac ggatacagat gtagacataa
      721 aacaagctca attttcaaaa atggcattac tcaccttttt ggtgaattat ttgtataaaa
      781 aaaatataga aaagacaccc tgaaatcctt tagaattaat ttggctacca attcatagga
      841 ggattcaaga tgtctcatac tcagcttatc aaagataccc taaatattct agacctaaat
      901 atctatttcg aggaaaattg tttaactaaa gaaaaataca aagggcaaat ttgcttgatt
      961 tacaaaggaa ctcttctgta caagccagaa gagtgttccc attgtctttg tgtcgtcccc
     1021 tctaggatca ttcgttgggg gacgacaacc gttcggttgt tactgaatga tgtgtctgag
     1081 tatcgcactt atctggagct gaagaaacaa cgatttaaat gtaagtcttg ccaaagaaca
     1141 ttcgtagcgg atacctctgt tgctgaaaaa cactgtttca ttagtcaaaa agttcgttgg
     1201 tctgtcattg ctcgcttaaa agagaatact tccatgacgg aaatcgctcg tcagaaaaat
     1261 atttccactt cttcggtcta tcgtgtcatg aagcgattct accgcccatt gaatcctttc
     1321 aaacagactt tgccaaaggt cttatgcttt gatgaattca aatcggttcg aagtgttgcc
     1381 agtgcaatga gttttatcat gatggacgga caaagccatg cattattgga tattgtcgaa
     1441 aatcgacgct tgccttattt agaacgctat ttttctcggt tttca
//
LOCUS       DAXLPC010000193         1449 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.201, whole genome shotgun sequence.
ACCESSION   DAXLPC010000193 DAXLPC010000000
VERSION     DAXLPC010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.201"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>1449
                     /locus_tag="ACF3UE_002801"
     CDS             <1..>1449
                     /locus_tag="ACF3UE_002801"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HFD3636117.1"
                     /translation="IRSGFQNLQPGMNYYPFYQEAQTRQIADWLIGMNASPLYTLNLQ
                     QKGVQGTFSLGRVQTPTLYLIFQRQEAIENFKKEPFFEVEASIKVNQGSFKGVLSPTQ
                     RFKTQEELLAFVSSKQAKIGNQEGIIADVQTKEKKTNSPSLFSLSSLQSKVNQLYKAT
                     ASQTLKAMQGLYEAKLLSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEMVQTEPR
                     KRYVDGSKVQEHHAIIPTKQVPTESALAKMDDLQRKIYALVVKTTVAMFLPDYLYEET
                     KIQTKVADLLFQSIGKTPKQEGWKILFKQQTKEEKEDVQTLPLVIIGERAEVGVKSVE
                     KETQPPKAFTEGTLLTAMKTANKTVDDEEAIKILQEVEGIGTEATRASIIEALKQKEY
                     IQVIKNKLVVTEKGKLLCQAVESQHLLTSAEMTAKWETYLKKIGKREGNQENFITNIK
                     KFIVHLLEAVPNDIEKLNFSDYQEQKEKEAEKS"
BASE COUNT          549 a          243 c          293 g          364 t
ORIGIN      
        1 atccgaagcg gttttcaaaa tttgcaacct ggaatgaatt actatccctt ttatcaagaa
       61 gcgcaaacac gccaaattgc cgattggttg atcggcatga acgcaagccc tttgtatacg
      121 ttaaatttac aacagaaggg cgtacaaggt acattttcac taggacgtgt tcaaacgccc
      181 accttatacc ttatttttca gcgccaggaa gccatagaga attttaaaaa agaacctttt
      241 ttcgaggtgg aagctagtat aaaagtaaac caagggtcgt ttaagggcgt tctaagcccc
      301 acacagcgtt ttaaaaccca agaggagctt ttagcttttg tttcttctaa acaagctaaa
      361 ataggcaatc aagaggggat aattgctgat gttcaaacca aagagaagaa aacgaatagt
      421 ccgagtttgt tttctttaag tagtttgcaa tcaaaagtca atcagcttta taaagcgaca
      481 gcgagccaaa ctttaaaagc tatgcaagga ctgtatgaag caaaattatt gagttatcca
      541 agaacagata caccatttat tacagagaac gaatttgctt atttaaaagc aaattttggc
      601 aaatatagcg gttttttagg acttgatctc gaaatggttc aaacagagcc tagaaagcgt
      661 tatgtggacg gtagtaaggt acaggaacac cacgccatta tcccaacaaa acaagtacct
      721 accgaatctg cattagcaaa aatggacgat ttacaacgaa aaatatatgc tttagtcgtt
      781 aaaacgaccg ttgccatgtt tttacctgat tacttgtatg aagaaaccaa gatacaaacg
      841 aaagtagctg atttgctgtt tcaatcgatc ggaaagacac caaagcaaga agggtggaaa
      901 attcttttca aacaacaaac caaagaagaa aaagaggacg ttcaaacgtt accactcgtt
      961 atcattggcg aacgtgccga agttggtgtt aagagtgttg aaaaagaaac gcaaccgcca
     1021 aaagctttta cagagggtac attattaact gctatgaaaa cggcgaataa aacggttgat
     1081 gatgaagaag caatcaagat tttacaagaa gttgagggga ttggaacaga agcgacaaga
     1141 gcaagtatta ttgaagcgtt aaaacaaaaa gaatatatcc aagtgattaa gaataagctt
     1201 gttgtaactg aaaaaggaaa attattgtgc caggcagttg aaagtcagca ccttttaacg
     1261 agtgctgaaa tgacggctaa atgggaaacg tatttaaaaa aaatcggtaa aagagaaggc
     1321 aatcaagaga actttattac gaatatcaaa aaattcattg ttcatttact ggaagctgta
     1381 cctaacgata tagaaaaact aaatttttct gattaccagg aacagaaaga aaaagaagca
     1441 gaaaaaagt
//
LOCUS       DAXLPC010000194         1432 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.202, whole genome shotgun sequence.
ACCESSION   DAXLPC010000194 DAXLPC010000000
VERSION     DAXLPC010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.202"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..1350
                     /locus_tag="ACF3UE_002802"
     CDS             <1..1350
                     /locus_tag="ACF3UE_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFD3636118.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
BASE COUNT          564 a          225 c          310 g          333 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gt
//
LOCUS       DAXLPC010000195         1424 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.203, whole genome shotgun sequence.
ACCESSION   DAXLPC010000195 DAXLPC010000000
VERSION     DAXLPC010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.203"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(150..1337)
                     /locus_tag="ACF3UE_002803"
     CDS             complement(150..1337)
                     /locus_tag="ACF3UE_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFD3636119.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAXLPC010000196         1403 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.204, whole genome shotgun sequence.
ACCESSION   DAXLPC010000196 DAXLPC010000000
VERSION     DAXLPC010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.204"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            5..1183
                     /locus_tag="ACF3UE_002804"
     CDS             5..1183
                     /locus_tag="ACF3UE_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFD3636120.1"
                     /translation="MENMSRFKKHITATGKITWYFQAFRTTRRGFNSKREAQLAYLEM
                     EKQHRNKQKRIASNDKFNVVSQKWFEYYRSLNEQKRATYDKREEQVKILNRWIGDKKL
                     SSLSSEELQKFLFILKEKGIDGIDVGYAKNSLQSLVQVLNMIFKYCKKKNLINENPME
                     FVKMPKYQLTVEDLKESVNSLEDKFLTVDELRTFLNYGIIYEELPMSVLFHVLFYTGC
                     RVSEALALQPQDIDFERNEILFYKQTAVKGKSKDFRIETTKSVSSARRVPVTPLVMEK
                     LHELIDVLNKTKRNSNFVVDETYLFVYLDPGKRGVPYRREYVNDHVKRCVERCGINKN
                     FHTHLARHTMASLVAEYCSWDVLKDRLGHTDSTTSKIYRHLTSNERIKPLLAFDSLEN
                     "
BASE COUNT          510 a          178 c          265 g          450 t
ORIGIN      
        1 acaaatggaa aatatgagtc gttttaaaaa acatattact gcaacaggaa aaattacttg
       61 gtactttcag gcttttcgaa ctacgagacg aggttttaat tctaagcgtg aggctcagct
      121 agcttatctt gaaatggaaa aacaacacag aaataagcaa aaaagaattg ctagtaatga
      181 taaattcaat gtggttagtc aaaagtggtt tgaatattat cgatcactaa acgaacaaaa
      241 gagggcaaca tatgataagc gagaagaaca ggtaaaaata cttaatcgat ggattggtga
      301 taaaaaatta agcagtttat cttcagaaga actacaaaaa ttccttttta ttttaaaaga
      361 aaaaggaatt gacggcattg atgttggtta tgctaaaaat agtttacaat ctcttgttca
      421 agttctaaat atgattttta aatattgtaa gaaaaagaat ttgataaatg aaaatccaat
      481 ggagtttgta aaaatgccta agtatcagtt aacagttgaa gatttaaaag agtctgttaa
      541 tagtttagaa gataagtttt taacagtaga tgaattgcga acttttttaa attatgggat
      601 catttatgaa gaattaccca tgtctgttct ttttcatgtt ttgttttata ctgggtgtcg
      661 tgtgagtgaa gcacttgctt tacaacctca agatatagat tttgaacgaa atgaaatctt
      721 attttataag cagacggcag taaaaggaaa aagcaaagat tttcgaattg aaactacaaa
      781 atctgttagt tctgctagaa gagtacctgt cacaccgtta gtaatggaga aattgcacga
      841 attaattgat gtattaaata aaacaaaaag aaatagcaat tttgttgtag acgagactta
      901 tttatttgtt tatcttgatc ctggtaagcg tggagttcct tatcgtcgtg aatatgtaaa
      961 tgaccacgtt aagcgctgtg tagagagatg tggaatcaac aaaaatttcc atactcatct
     1021 ggctcgtcat acgatggcta gtttagtagc tgagtattgc agttgggatg ttttaaagga
     1081 tcgtttaggt catacagata gtacaacttc aaaaatatat cggcatttaa catcaaacga
     1141 aagaataaag cctttgcttg cttttgattc attagaaaat tagattttgg cagaagtgca
     1201 ggtattttag aatctaaaat aggtgttgtg actatgcttt agtcaaagtg tagtcagaaa
     1261 aagagaaaaa cttttatatc aatactttaa tgacttttca caagtatcaa agaaatccgt
     1321 cgttaatcat tgttatcaga ctgagaaaga acccttggta ttcaagggtt cttttttctt
     1381 agcatgtaat ttgaacaccc tga
//
LOCUS       DAXLPC010000197         1389 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.205, whole genome shotgun sequence.
ACCESSION   DAXLPC010000197 DAXLPC010000000
VERSION     DAXLPC010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.205"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            476..727
                     /locus_tag="ACF3UE_002805"
     CDS             476..727
                     /locus_tag="ACF3UE_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636121.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
     gene            761..1039
                     /locus_tag="ACF3UE_002806"
     CDS             761..1039
                     /locus_tag="ACF3UE_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636122.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
BASE COUNT          493 a          192 c          261 g          443 t
ORIGIN      
        1 atacaaataa ttggtttatt ctggcaggcg taatgctttt ttctagtttc tatttattta
       61 gtaatgctct attagcacag cgagggaaat ataagtttaa aatattagat tagatattat
      121 ttttagaggg gataaatata aaatgaaaag aggttattta taatggaaaa agtattacca
      181 attaagagct actgtattcc aaggcttttc atcatagaat ttcaaaagta aagacatgtg
      241 tttcacaaat agtgtctatc ctggctaaat aattcttcca ctatctgctt taatttcagt
      301 agacttttcg gcaagttatt tgctaatgag atgaatagag attacaactc gcctataacc
      361 gcttaaaaca agctttttta aagtatagtt agcaagtcgt attcatatgt tcaaagagga
      421 gggcttatga actttgaatt cattccgtgt gaacagaaca gtagggggaa gtaaaatgaa
      481 agaaaagcct ataaataaat ggtcattgta taaaaattca atgtttggag ttgttatctt
      541 tggtgtttgt gctggattat tccttttcat attattacaa acggtgactc ttttctcttc
      601 taatcctact tatggatgga gagacagtat agccttaggg atgtttgcgg gaggatatgg
      661 attcttattg ttgttctcaa ttctcacact aagtccaatc catggactca ttcaactttg
      721 gaagtaagaa cgagccttaa acttttcgtt ctcggaagaa atggaaaaac acaacataac
      781 aggcagtatg tatgtggatg atcaatggtt tatcagcact gatgaggtaa aaatagctgc
      841 cattaggaga gattacctgc agaaaattca taaaataaaa gatcctaatg ggaaaaaggc
      901 aaggttaatt ataactttga taacatctaa tggtaagaag ttaaaacttg caggatcata
      961 tgataatgtt aaaaagttcg aacattggta tctgcaaaaa gacagcatta gtcttaataa
     1021 acaatttgaa aaaaattaat caaagtcatc ggcaacacga ataatttgac atcttgatat
     1081 tgtgatataa gcaaaaacgg catttctgag accgaacagc ataaaaaatt taaatgttgg
     1141 aatttatata agcaaaaccc aagaagctag atgcgataga gcatttaatt tcttggggtt
     1201 ttgcttggga atcagcatat caattaaaat gatcatctcg gtatttcaaa agtgggtacg
     1261 attacaaata gttggagcaa aatagtgggt aaaattacca ttccagtgtc tgtcttgcct
     1321 ctttttcgtc aatcacaaat agacgagatt cataggaaaa atcgatacag ggtatgattt
     1381 caatgatat
//
LOCUS       DAXLPC010000198         1389 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.206, whole genome shotgun sequence.
ACCESSION   DAXLPC010000198 DAXLPC010000000
VERSION     DAXLPC010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.206"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            278..820
                     /locus_tag="ACF3UE_002807"
     CDS             278..820
                     /locus_tag="ACF3UE_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636123.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            976..>1389
                     /locus_tag="ACF3UE_002808"
     CDS             976..>1389
                     /locus_tag="ACF3UE_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFD3636124.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDGMATLFLTKIIRCCECCGVMA"
BASE COUNT          551 a          164 c          265 g          409 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcaaat tgatgaagca gatcccaaag ggctgcttca tcaatttttt
      121 cgtaagtgtc cgtacactta ctgtgcttgc tcatatatta atcgatcata tactaatcgt
      181 gtaagaacaa ctttaagcat aatacttata ttgttatacc atagtttgga aaaataaaaa
      241 attatatttc atcaacgttt cataaaaggt gtgtagaatg ttattgaaag tagctataaa
      301 atgctattgt gtaaaaaata aaggaggaat aatttatgaa aaaatagtac caagaggagc
      361 atgcctatta cttgcattat gtttgagctt aagcgcagtt gggtgtcaaa aaagtaatga
      421 aaacaataaa ataaaagaag gacaatccat aagttctgaa gaggaaggca tgtcaattaa
      481 tgcaaatggc aaaaatgaaa cttttaagcc atcagattat acattggagg caaagaaaga
      541 atatgtttat gaatatttag ggcttaaatt taaactctca gacaaattta gaaattatat
      601 agctgataaa aagatagcga tgttagatga tcaaagtcct atagataaag aactaaagta
      661 tgctattttg acatttgaga aaatgacaga agaacaaaag aatgcagtta tagaaaagat
      721 gggcgatgga tataaaaatt ggcaaaatga gcttgaaaga attgggacta ttggtatatt
      781 tgaaaaaaat acatcagaag aaaaaaatct aaaattataa aatgtgatac tcatactaaa
      841 ataggagttt caagtgatgg aaaatacgat tgctatttaa gcacaaatag cggagctgaa
      901 agtaatcttc tggatgaatt aaaaagaact gagattcaaa ttatagataa aaaagaacgt
      961 cctaaaaatg gttttgtgct atcagaaaaa actgatttag aaaatacaga agcatttaac
     1021 aaagaatcgg ttaaagattt acgtaaacta ccaacaaagg acataaatgg caaggatttt
     1081 acaagtaaag attttgagaa gtatgatctt actatggtaa atgtatttgc aacttggtgt
     1141 acagcttgtg taaaggaaat tcctgatttg gttgaggttc agaatgaaat gaaaagcaag
     1201 ggtgtaaata tcgttggagt tgttacagat cctgttgatg ataacggtga aaacaaggaa
     1261 gcaattgaaa agtcaaagtt aatacatgaa aagacaaagg cttcatatcc tttcttaatg
     1321 ccagatggaa tggcaacact ttttttgaca aaaattataa ggtgttgtga atgctgcggt
     1381 gttatggct
//
LOCUS       DAXLPC010000199         1364 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.207, whole genome shotgun sequence.
ACCESSION   DAXLPC010000199 DAXLPC010000000
VERSION     DAXLPC010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.207"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            80..>1364
                     /locus_tag="ACF3UE_002809"
     CDS             80..>1364
                     /locus_tag="ACF3UE_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFD3636125.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLI"
BASE COUNT          465 a          263 c          257 g          379 t
ORIGIN      
        1 tttaggtatt aaaaaacata tcgttctcta gtatgattaa atcaccacaa aataaacaac
       61 tgagaggacg atacgctata tgaatgattc tatcaaaaaa atgctgagaa taacagagaa
      121 agatttgatg attacagagg tctcttacga gacccttcag aagaaaaaga cgttggtcgt
      181 cgatgctgtt ctctcgccta ctcctcgtgc ttgtagaagt tgtggttcta ctgtggtaga
      241 tggaaacggg aaagcaatta tagtgaaaaa tggaaaaaag gaaacgattg tccgttttga
      301 acaatacaat catatgcctt tggttatgcg cctaaaaaag caacgctata cctgtaaaaa
      361 ctgtcgcacc cattggacgg ctcaaagtta ttttgtccaa cccagacatt caatcgcaaa
      421 tcatgttaga tataaaattg cttctttact gactgaaaaa gtatctttat cttttattgc
      481 gaaaagctgt caggtatctt tgaccaccgt tattcgtaca ttgaaagagt ttaaaagcta
      541 tttaccaaag caatctaaga agatcctccc cagagtattg atggttgacg aatttcgttc
      601 gcatgcttcc atagaagata agatgagctt tatttgcgcg gatggcgaaa caggaaaatt
      661 aatagatgtt ttgcctacgc gtaaattacc tcgattaaca agctatttct taggttgtac
      721 caatccagaa gaagtagaat tcttggtgac agacatgaac gccgcctact tccagctcac
      781 caaacgtgtt ctgccaaatg cgaaagtcgt gattgatcgg tttcatattg tcaaacacat
      841 gaatcaagcg ttcaatgagt tgcgtatccg tgaaatgaat gaacttcgta aagccggaca
      901 gaaaagccag gcagaaaaac tgaaaaagaa ctggcgcttt ttgctaaaaa atcgtgcaaa
      961 catcaaccat tatgaataca aaacatggaa aagtttccga gcaccaaaat acccatttct
     1021 tactgaagca atgatgattg atcgattgct tgagttttct ccgcccctaa aggaggcgta
     1081 tccctttttt catgaattag ttgaagcctt tcgagacaaa gaccctgact tatttttctc
     1141 cttattggca gaacttcccg aaacgttaga tgacagcttt cgggaaaagc ttcaaaacct
     1201 tctgacctat gaagaaggca tcaccaacgc aatgatctat ccttattcca atggaaaaat
     1261 agaagcgaag aatacccaca taaagacaat gaaacgagta tcctacggat ttaaatcatt
     1321 tgagaacatg agaattagaa tctttttgat caatcaatta atca
//
LOCUS       DAXLPC010000200         1362 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.208, whole genome shotgun sequence.
ACCESSION   DAXLPC010000200 DAXLPC010000000
VERSION     DAXLPC010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.208"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            55..>1362
                     /locus_tag="ACF3UE_002810"
     CDS             55..>1362
                     /locus_tag="ACF3UE_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFD3636126.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFI"
BASE COUNT          529 a          158 c          233 g          442 t
ORIGIN      
        1 agtgttagtt aaagatgaat atacttttta tagaaaggaa aagaatgtaa ttaagtggaa
       61 aaaatagtaa ttattggttc aaaccattca gggctagccg cagctcgatt tctaaactta
      121 agcgattcaa attatgaagt tattctaatc gataaaaaat cagaaattag ttacttggaa
      181 tgtgggacat cgttatttat aaaaggagaa gtaagtaatt tagaagatct tttttatcaa
      241 aatagaatga cactaaattc tgagataaaa aagttatttc tagagacaga agttgacaaa
      301 attgatattc aaaataaaaa gattagttgt gtaaaaaaag atggtacaag attctctcaa
      361 gaatatgaca aagttatatt agctacaggt tcaaagcaaa ttatgctaga tataccgggg
      421 aataatttag ctaatatttt ttcgataaag aattttccaa atgcaaaaga gatttttaaa
      481 gctttggatg atagtactat taaaaaagta ggaattattg gagcaggata tattggagtt
      541 gaaattgctg aagccataag aaaaagaggg aaagaagtat atcttttcga tgttgcagat
      601 agagtgttgt cgacttatta cgaccgtagt ttttcagata aagttgaaga aatactatca
      661 aaaaatggaa tacatctttg tctatcagaa agtcctaaaa aatatttagg aagaaaaaag
      721 attgaaaaaa tagtcactac aagtggtacc caatactcta tggatatggt cgtacaagct
      781 ataggatttc tatctaatag tccaattggg gaaaaggaac tcttgagaga tgttagtgga
      841 gcatatctaa ctaatgaata ccagcaaaca aatataaaag atatatatgc tattggggat
      901 tgtgctacaa ctttttttac gtccattaat agaagtagtg ttgatttttc tatttctaat
      961 gctctaagaa cagcttatat tgcaactcaa catattaaca atcaagattt tacaccttct
     1021 ggttcccaat ttacaaatgg cttttctata tttaattaca atttttacgc agcaggtttg
     1081 aatttaaaaa cagcacgatt attaagtgag tctatagatt atatagaaat agaagatttc
     1141 attagacctg cttttttgag aaaaaatagt cgtgtaaaat taagaattag ctttgaaaaa
     1201 aatacaaaga gaatagtagg tgtacaactt tgtagtcaag aagatttatc tggactatta
     1261 tcaatgtttt ctcttgctat agaagaacaa attacattag acaaattgaa aatgttagat
     1321 tatttatttc atcctagttt tagccaaccc tataatttta tt
//
LOCUS       DAXLPC010000201         1361 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.209, whole genome shotgun sequence.
ACCESSION   DAXLPC010000201 DAXLPC010000000
VERSION     DAXLPC010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.209"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..486
                     /locus_tag="ACF3UE_002811"
     CDS             <1..486
                     /locus_tag="ACF3UE_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFD3636127.1"
                     /translation="LKEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKE
                     QQVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFS
                     NNQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVI
                     K"
     gene            complement(693..1217)
                     /locus_tag="ACF3UE_002812"
                     /pseudo
     CDS             complement(693..1217)
                     /locus_tag="ACF3UE_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          445 a          254 c          260 g          402 t
ORIGIN      
        1 ttaaaggaag cgatcgatca aatcaagacg gctgtcttgt atcctcataa cggattaccg
       61 attttattga tgggtgtaag cggttcagga aaaacctttt tggcagaaaa aatttatgaa
      121 tacgccaagg aacaacaggt gatagaatca aatgctccat ttatcgccta taattgtgct
      181 caatacttta atttctcgat taacaagatc gtagaaaatt taacgatcct tgatgcaatg
      241 aaggttttga gattggtaca aaaggccgtc aaagaactcg aaaaactaat ggggatcgaa
      301 ttttcaaaca atcaattgtt cttgctttac atgcactgct gctcaatgat cgaacgtatt
      361 ttacgcaaag aaagtgtaga tgaacaagca gatatcaaag aatatattca aaaagaggga
      421 cataattatg aaatatcaaa atacccggct tacaaaacga agtttgaaag tactgtaata
      481 aagtaagatt taaataagca taaacaaggt aagaaccata ggggctgtgt caagtccaaa
      541 atcttgtgta aaaaggaaat ctcaaagtac gatgttttgc cttgttgagc ctagctacgg
      601 tccaatatgc tggtaagaag tgtcaagagc aaaaagcgaa gcgtctcttg atacttctca
      661 ccagtatatt atactattgg cggcttaatg tgctaaatct cgttacgatc aaattcaaga
      721 tattttctag gtgcagaagt ccattcgtca tccttttcca tcaataaagc accgatgata
      781 cgaataacag aatcacaatt tgggaaaatt cggacaacac gttcacgacg gcgtacttct
      841 tcatttagtc tttcaagaac attcgttgtt ctcaatcgtt gacggatatt ttctggtaaa
      901 accattactt gcatggcatc ttcgaagccc tcatccaata ttttacaggc agttgcgact
      961 ttcttgtctt ccccatattt atccataata agttgtttac gttctccagc cagctcgatg
     1021 cttgccgttt tgaagatggc tttaaagtct tctttgatat cgcttgagat tttcttggag
     1081 aatttgtcgg aaatgttgcg aaggagatgt gcttggcatc tctgctagct cgcacaaaga
     1141 aggtattctt tcacagcttt tgtgagccct atatgcgcat ccgagatgac catctttact
     1201 cctgaaagac cgcgttcttt caatccgaga gtgtaaaata ttttgtgtaa atagaaaaaa
     1261 ggaagtccct tcagtagaat agagttacca caacacattc acagaaaaga ggacttccat
     1321 atgaacgatt ttactacaga aattctaaag actctagcga a
//
LOCUS       DAXLPC010000202         1345 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.210, whole genome shotgun sequence.
ACCESSION   DAXLPC010000202 DAXLPC010000000
VERSION     DAXLPC010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1345
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.210"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..281)
                     /locus_tag="ACF3UE_002813"
     CDS             complement(<1..281)
                     /locus_tag="ACF3UE_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFD3636128.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFY"
     gene            complement(281..1123)
                     /locus_tag="ACF3UE_002814"
     CDS             complement(281..1123)
                     /locus_tag="ACF3UE_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFD3636129.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(1125..>1345)
                     /locus_tag="ACF3UE_002815"
     CDS             complement(1125..>1345)
                     /locus_tag="ACF3UE_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFD3636130.1"
                     /translation="SERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLI
                     AHGSVESVFNEENLKKAYGDTIFIGEGE"
BASE COUNT          491 a          250 c          156 g          448 t
ORIGIN      
        1 ttataaaaaa tcaaatctgc ttttgaagtt ttttgaacat cttcaggcaa aggttcatat
       61 tcgtggggat ctttcccaat aggtacgata ctgtgtaaat caattttatc ttttgctata
      121 ttttcggtaa tatctgctaa aatcgaatta gtaactacta cttttaattt ttcgttcgaa
      181 gccactttat ctttgtcttt actatttatt gaacatgccc cgaatataaa aagagcaatc
      241 aaaatcccca gacttcccag tactgctttc cattttctca tcataacgat ctctccttct
      301 ttcttaaaaa tttttgtttt ggtgagatta gaaaactaat tacaaataag aatgccgctg
      361 ttaaaacaat acttgatcct gctgctatgt taaaactata accaataaac aatccaagca
      421 atgatgaact tgctccgact gttgcagaaa taaatatcat agttttcaag ctatttgcat
      481 ataaatatgc tgtagctgct ggtgtaatta acattgcaac aattaatata gttcccacac
      541 tttgcatagc tgttactgct actaaagtta atagaaccat caatagataa tgataaaaac
      601 tgacattcat ccctattgct tttgccatta atggatcaaa agaagtgatt aataattctt
      661 taaaaaatag aactactata accaacacta aaaccgaaac gccaattgta atccacttat
      721 caatatcttg tacagctaaa atatttccaa ataaaatatg aaataaatcc gttgagctat
      781 ttgcaactcc tataaggata actcctagtg ctaaaaaaga actgaaagta ataccaattg
      841 ctgtatctcc ttttattaca ctattgcttt ttataaaagt aataatgata gaagctaata
      901 gaccaaatac aatcgcacca ataaaaaaat taatacctaa aatataagaa attgctactc
      961 ctggcaaaac agcatgagaa atagcatcac ccataagaga cattcctctt aaaataataa
     1021 aacaacctac tgttccagaa acaatcccta taactacaga tgtaattaga gcattctgta
     1081 aaaagtgaaa gtcatacaga ccattaataa aattttgaag catattattc cccctctcca
     1141 ataaatatag tatctccata ggcttttttt aaattttctt cattaaatac agattctaca
     1201 cttccgtgag caattagatt tcgattcaaa agaataatat tatcaaaata cttctttacc
     1261 ttgcttaaat catgatgcac aattagcact gtttttccct gatgtttcaa tttttttaac
     1321 gtatccataa ttattcgttc actaa
//
LOCUS       DAXLPC010000203         1297 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.211, whole genome shotgun sequence.
ACCESSION   DAXLPC010000203 DAXLPC010000000
VERSION     DAXLPC010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.211"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..152
                     /locus_tag="ACF3UE_002816"
     CDS             <1..152
                     /locus_tag="ACF3UE_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3636131.1"
                     /translation="TYLNTLLSNSFIINQIVEPQPPENMMDIPGMADEMRRPMMLIVS
                     AKKKM"
     gene            185..1093
                     /locus_tag="ACF3UE_002817"
     CDS             185..1093
                     /locus_tag="ACF3UE_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFD3636132.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            1090..>1297
                     /locus_tag="ACF3UE_002818"
     CDS             1090..>1297
                     /locus_tag="ACF3UE_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636133.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDN"
BASE COUNT          462 a          185 c          294 g          356 t
ORIGIN      
        1 ccacatatct aaatacactg ctttcaaata gttttataat aaatcagatt gtggagccac
       61 agccgccaga gaacatgatg gatattccgg ggatggcgga tgaaatgcga cgcccaatga
      121 tgctgattgt atcggcaaaa aagaagatgt aataatatag aaaaaataaa cgaggagtat
      181 gtaaatgaga tcagaaaaag aaatgatgga tttagtactt tctttagcag aacaggatga
      241 acgtattcga attgtgaccc ttgaggggtc acgcgcaaat attaatatac ctaaagatga
      301 atttcaggat tatgatatta catattttgt aagtgatata gaaccgttta tatctaatga
      361 tgactggctt aatcaatttg ggaatataat aatgatgcaa aagccggagg atatggaatt
      421 attcccacct gaagaaaagg gattttccta tcttatgcta tttgatgatt acaataaaat
      481 tgatcttacc ttattgccct tggaagagtt agataattac ctaaagggcg ataaattaat
      541 aaaggttcta attgataaag attgtagaat taaaagggac atagttccga ctgatataga
      601 ttatcatgta agaaagccaa gcgcaaggga gtatgatgat tgctgcaatg aattttggaa
      661 tgtaacacct tatgttatta aaggattgtg ccgtaaggaa attttatttg ctattgatca
      721 ttttaatcag attgttcgcc atgagctgct gagaatgata tcatggaagg tcggcatcga
      781 aacaggcttt aaattaagtg taggcaagaa ctataagttt attgaaaggt atatatccga
      841 ggatttgtgg gagaaacttt tgtccaccta ccggatggat tcctatgaaa acatatggga
      901 agcattattt ctatgccatc aattgttcag ggcggtatcc ggtgaggtgg cggaaaggct
      961 tcattatgcc tatccggagt atgataggaa tataacaaaa tataccaggg acatgtataa
     1021 aaaatacact ggtaaaaccg gctgcctgga tagcacatat gccgctgata tagaagagag
     1081 gcgggaacag tgattacaga aatgaaagca gggcacctga aagatatcga taaacccagc
     1141 gaaccatttg aggtgatagg taagattata ccgaggtatg aaaacgagaa ttggaccttt
     1201 acagaattac tctatgaagc gccatattta aaaagctacc aagacgaaga ggatgaagag
     1261 gatgaggagg cagattgcct tgaatatatt gacaata
//
LOCUS       DAXLPC010000204         1287 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.212, whole genome shotgun sequence.
ACCESSION   DAXLPC010000204 DAXLPC010000000
VERSION     DAXLPC010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.212"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            256..1044
                     /locus_tag="ACF3UE_002819"
     CDS             256..1044
                     /locus_tag="ACF3UE_002819"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636134.1"
                     /translation="MEKINESKVSVCKEKGESYFLETLSLKQQEDKLFSEWEKEECLK
                     GYYGINQDGLADESSYLQSLPKIAFILKEAYGKENFDMRPYYYDGAHAGSKTWRTAPL
                     WIAGISKIYEENKSTIAQIKTEKRNMGWKEFNQEYIRKVAILNLNKQCTTNGKLTDRK
                     YFQSGIDNKKFINKQIEIYNPEIIICGGTFYPFYDRIYDYKNFDTKYESANQNKQYAE
                     GYKDKKGRLIINTFHPGAIKKEEPWYDSIMEIVERFKSEGLFAK"
     gene            complement(1130..1234)
                     /locus_tag="ACF3UE_002820"
                     /pseudo
     CDS             complement(1130..1234)
                     /locus_tag="ACF3UE_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          473 a          189 c          244 g          381 t
ORIGIN      
        1 ctcctggtat gttttcttct agtctacaca ccttaatttt tctgtctagt taattgtagc
       61 ctatccagag tataatcatt gtaaggtcaa gtatttgact ttttcgatta tgagagcgtt
      121 accttttcta ttactgaagc ctttataaaa tggcgaaata atagaagaaa ctgaaagctc
      181 ttaataaata gacaaactac gttccaatag acgttttaaa aagggtatga aatacagcat
      241 acaaggagtg aaaaaatgga aaaaataaat gaaagtaaag tatcggtctg caaagaaaaa
      301 ggtgagtctt attttttaga aacgttatcg ttaaaacagc aagaagataa gctgttttct
      361 gaatgggaaa aggaagagtg cttgaagggg tattatggga taaatcaaga tggactggca
      421 gatgaaagta gctatttaca atcacttccg aaaattgctt tcatcttaaa ggaagcatac
      481 gggaaagaaa attttgatat gcgcccttat tattacgatg gtgctcatgc tggaagcaaa
      541 acttggcgaa ccgccccttt atggattgct gggatatcta aaatttacga agaaaataaa
      601 agcactatag ctcaaataaa aactgaaaaa agaaatatgg gttggaaaga gttcaatcaa
      661 gaatatatac gaaaggtagc tatcctaaac ctcaacaaac aatgtacgac taatggaaag
      721 ttaacggatc ggaaatattt tcaatccggt atagataata aaaaatttat aaataaacaa
      781 atagagatat acaatccaga aattattatt tgtggaggaa ccttctatcc gttttatgat
      841 cgtatttatg attataaaaa ctttgatacc aaatatgaaa gtgccaacca aaataaacag
      901 tacgcagaag gatataagga taaaaaaggc cgattgatta taaatacttt ccatcctgga
      961 gccataaaaa aagaagagcc atggtatgac tctataatgg aaatagttga aagattcaaa
     1021 agcgaaggct tgtttgctaa gtaagtgagt tccttcttcc aaattacaaa aaataatgga
     1081 taggctacac accttaattt ttctgtctag ttaattgtag cctatccagt cgcgcacgtc
     1141 ctaagcattg cgcagttttg gtaacggatt gattattttt gaaataagac tctatgacta
     1201 ctagttcgtc tgttgtaaga tgggtgtagg tcatttgtac tcactcctta ataattcttt
     1261 ggtcggaact attttgagtg tagcaca
//
LOCUS       DAXLPC010000205         1282 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.213, whole genome shotgun sequence.
ACCESSION   DAXLPC010000205 DAXLPC010000000
VERSION     DAXLPC010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.213"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            81..1253
                     /locus_tag="ACF3UE_002821"
     CDS             81..1253
                     /locus_tag="ACF3UE_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HFD3636135.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          478 a          235 c          227 g          342 t
ORIGIN      
        1 taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac
       61 atacccagga ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc
      121 aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat
      181 ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa
      241 cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag
      301 gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg
      361 aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg tatgtatcag
      421 gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa tccgtctcta
      481 agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag tggcagaatc
      541 gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat ataaaagtac
      601 gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata accaaagatg
      661 gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag acctggacaa
      721 cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt atttctgatg
      781 cgcacaaagg attagtctct gccattagaa aatccttcac caacgtaagt tggcaaagat
      841 gccaagttca cttcctaaga aatatcttta ccaccattcc taaaaaaaat tcaaaatctt
      901 tcagagaagc tgttaaagga atttttaagt tcacagatat taacttagcg cgtgaggcta
      961 aaaatcgatt gattcatgat tatatcgatc aaccaaaata ttcaaaagct tgcgcatcat
     1021 tggatgatgg attcgaagac gcctttcaat ataccgtaca aggaaattcc cacaatcgac
     1081 taaagagtac caatctaatt gaacgactga atcaagaagt acgcagaaga gaaaagatta
     1141 ttcgcatctt ccccaatcaa acatcagcca atcgcttaat tggagccgtt cttatggacc
     1201 tacatgatga atggatttat tcttcaagaa aatacatcaa ttttgataag tagaaatggt
     1261 aaaaacattg tatagcattt ta
//
LOCUS       DAXLPC010000206         1271 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.214, whole genome shotgun sequence.
ACCESSION   DAXLPC010000206 DAXLPC010000000
VERSION     DAXLPC010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.214"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..582
                     /gene="mobL"
                     /locus_tag="ACF3UE_002822"
     CDS             <1..582
                     /gene="mobL"
                     /locus_tag="ACF3UE_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase MobL"
                     /protein_id="HFD3636136.1"
                     /translation="MNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVL
                     TKEPEYQEYIQISKSLKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQD
                     SQIKPLIESMDQMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLR
                     QLNRTINAHEEKYHASKAYEEQQRRIQMEQERQ"
     gene            603..938
                     /locus_tag="ACF3UE_002823"
     CDS             603..938
                     /locus_tag="ACF3UE_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636137.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYSATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            1084..>1271
                     /locus_tag="ACF3UE_002824"
     CDS             1084..>1271
                     /locus_tag="ACF3UE_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636138.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT          502 a          192 c          264 g          313 t
ORIGIN      
        1 atgaacttat taaatgaagt atataaaacc ctacctgaca aacgttcgga atggcattat
       61 ggggatgaaa aacgaaccaa actttcacca tacacaagag agaaactcga tgagttaacc
      121 aaatatgtgt taacaaaaga acctgaatat caagaatata tacagatttc aaaatcattg
      181 aaagaagaag caaaaagtct ttatggggaa agcaagagag aatcaaagga tgcagaaaaa
      241 aatgctctct ttgatttgaa gaagcgcaca ggaaatgcca ttctaacaga actgaagaaa
      301 caggatagtc aaataaaacc tttaatagaa agtatggatc agatgcaatc tatttacaat
      361 gaacgatcct ttcgaacgct taaacagtta ccaacgaatg aatacaaata tagttacgaa
      421 gaattcatga agcgcaggaa acaattccaa caaagagttg tcacgcaacg gagtttgcgt
      481 caattaaatc gaacgattaa tgcccatgaa gaaaaatacc acgcaagtaa agcctacgaa
      541 gagcaacaac gaagaattca aatggaacaa gaaagacagt aaagacagta ggaggaatag
      601 caatgaaaca atatttagat caatggaaag ttatagaagg atcattaaga gaagaacgaa
      661 tcgaacaact tcccgattgt ttagaaaaag agcatttgtt tcagataaga gaaatgttga
      721 gaaacgaaca gtttgatcca aatcaatttt tagtcgttga gtactcagct actggtgtgt
      781 actgttgtaa tcatgtgaag ggtgaaaaat attttatcat tcaagaatat gagggcaagt
      841 tagcgcctta ttatactact tgggaaatga atgaagaggg gatcaataac ttcccgtgta
      901 aaagcattga agagtctatt tcactcacag aatgttagtt gttaagtgaa taaaagaagt
      961 aaaagagtcc tgaacgtaat tgtccaggac tctttttttc aatgaattgt tttccgccaa
     1021 ttcaatgagt ggtgcgattt gcgactacat tatatcaaaa gaaagagaag ggaggaagaa
     1081 gaaatggctt attcaacgat tggagttgtt gttgaaaaaa gcagagacaa tctcgttttt
     1141 gtgacagaaa ttcaaacggg cagagctttt gtcgtcacag acaaagcggc aaaagcgtat
     1201 caaagtggcg atattttaac gttaaatctg actacgaaga cgttcgtcga tgcggcagaa
     1261 gattatccat t
//
LOCUS       DAXLPC010000207         1264 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.215, whole genome shotgun sequence.
ACCESSION   DAXLPC010000207 DAXLPC010000000
VERSION     DAXLPC010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.215"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(361..717)
                     /locus_tag="ACF3UE_002825"
     CDS             complement(361..717)
                     /locus_tag="ACF3UE_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFD3636139.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(731..1141)
                     /locus_tag="ACF3UE_002826"
     CDS             complement(731..1141)
                     /locus_tag="ACF3UE_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFD3636140.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
BASE COUNT          409 a          233 c          179 g          443 t
ORIGIN      
        1 gatagaatca agcttcgcaa gtggttcttt ttcaacgact cagttatctt atcatgtcat
       61 ttccaacatg tcaacaacta ttttatatgt tttttaaaat actattttat tgctttgcta
      121 cttaaaacaa cagaaatgaa tatatcatgt aaatttacac atgtcaatat atttttaact
      181 ctatatcccc acctagattt gaattttgac cacataaatt gagcatgtct ctataaattg
      241 agcatgtctc tatagtagaa aaataaagtc aaaaaaagaa cacataacac gcttgatgct
      301 aagtgttcga ctgttacaac tgtatgaaat gctcagtgac ttgattaaaa cagttaaagt
      361 ctatttattt aagataagct gttccatcaa ctgctcattg tatccaataa atagaacttc
      421 atcgataata atcaaaggac gtctgaggag attggtatgt tgtgtgcata aaaaaatcag
      481 ttgttttttt cctacacagg aaaggtcaat cgcaatgttg tgaaaagcct cagaccaagt
      541 cgcaaatagc tgttctgctt gcacttcttc aaaactgcat aattcttctg cttcttctgt
      601 acttagatcg cgttcttcta agtcaacaaa ttgataaggc aattgatggt gttctaacca
      661 ttgtttcgcc ttcagacttg ttacacagtg cgctgatcca tagactttca cttccacgaa
      721 ggctccctcc ctatgaattt aagatgttat tgttttgtaa atagatcaga tttctggcaa
      781 cacatcgaat ttcacgaggg acaaatgacc ggatctcatc ttcattaaat ccgattagta
      841 ttcttttttc atcaatcaaa ataggtcgtc tcaataatga aggatattct ttgaataaga
      901 cgatcatttg ctttaaagtt aattcgttaa aatctatgcc cagcttttcg taaattttcg
      961 accgagtgga aataatatct tgaactcctc cttcagtcgc tgccaagatc tttttgatct
     1021 cactttctgt taacggttcg gcaaaaatat tcttctcttc aaattcaagt tgattcgctt
     1081 gcaaccatgc tcttgctttt ctacaggaag tacagctagg cgaagtatat acttttatca
     1141 ttttctcact cctttttaat tataatccaa ttctacagta atttttttta aaataccaat
     1201 tattagctaa taaaatataa aaaaaaaaaa aatcaaaata actgattatt tacgtttgaa
     1261 taat
//
LOCUS       DAXLPC010000208         1264 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.216, whole genome shotgun sequence.
ACCESSION   DAXLPC010000208 DAXLPC010000000
VERSION     DAXLPC010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.216"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..660
                     /locus_tag="ACF3UE_002827"
     CDS             <1..660
                     /locus_tag="ACF3UE_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFD3636141.1"
                     /translation="FCQKLGFSGFSDLKIEIAKEDFSKKKEYPSSEKYYDIIATHLTE
                     ALYSTAHLLDEKKLDKAIQLISQAKNLYIFGVGSSGNTSLDLESMFLRVGVQAKAVLD
                     PHFQAQVASLMEEDDVIIAFSLSGKTKDTFDSVEIAKKNGAKILAITNYLHSPIGQTA
                     DVVLQTAIEEFLNGGSLAGKISQLYLCDLLVQGYEQKNNINAVELRERVLRSILDKSL
                     D"
     gene            complement(1021..>1264)
                     /locus_tag="ACF3UE_002828"
     CDS             complement(1021..>1264)
                     /locus_tag="ACF3UE_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFD3636142.1"
                     /translation="KFSFYFKFIESPKVKDRYTLLFIDNLITIYIYSYFNVFYRKKLL
                     LYLSLYQQDKQSIEFEEDLLKHLKILIRTRLFIDKN"
BASE COUNT          491 a          173 c          190 g          410 t
ORIGIN      
        1 ttttgccaaa aattaggatt ttctggtttc tctgatttga agatcgaaat tgcaaaagaa
       61 gatttcagta aaaaaaaaga atatccgtca agcgagaaat attacgatat aattgctact
      121 catctaactg aggcgctcta ttctacagca catttactag atgaaaaaaa actagataag
      181 gcaatccaac tcatcagtca agcaaaaaat ctttatatat ttggggtggg ttctagtgga
      241 aatacaagcc ttgatttaga aagtatgttc ttacgagtag gagttcaagc aaaagctgtt
      301 ctggatcctc attttcaagc tcaagtagct tctttgatgg aagaagacga tgtgattatt
      361 gctttttcat tatccggaaa aacaaaagat acctttgatt ctgtagaaat tgcaaaaaaa
      421 aatggtgcaa agatcttagc aattaccaat taccttcatt ctccaatagg acagacagca
      481 gatgttgttt tacaaacagc aatcgaagaa tttttaaatg gtggttcttt ggcagggaaa
      541 atctctcaat tgtacctttg tgatttactt gtacaaggtt atgaacagaa aaacaatatt
      601 aatgcagtgg aattacgtga aagagtatta cgctctatct tagataaaag cttagattaa
      661 atagagtatt aattgaagca atttatattt aggtgaaata tcaattaatt agtgggactc
      721 acaatttgca caaataactt tcatcttacc tttagatgaa gtgttagaaa gaaaagtatc
      781 aaccatcaat actttgaaaa aattcttttt ataggaatat gatgaacagc tttcaatata
      841 caataatcat tatcaaagat aactgacaac ttttagcaat aaaatacaaa acactttttt
      901 agtcagtatc taaatataac aaatctattt cataaagcaa aaaagcggct agacaaaaga
      961 gatgtctaac cacttacatt tatcatctat ataattcaat gaacagagaa aaaaaggaca
     1021 tcagttttta tcaataaaaa gtcttgttct tatcaatatt ttcagatgtt ttagcagatc
     1081 ctcttcaaat tctatagatt gtttatcttg ttgatataaa gatagataaa gcaataattt
     1141 ttttcgataa aatacattaa aatatgaata gatataaata gtaattaaat tatctataaa
     1201 caataatgta tagcgatctt ttaccttagg ggattctata aatttaaaat agaaagaaaa
     1261 tttt
//
LOCUS       DAXLPC010000209         1215 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.217, whole genome shotgun sequence.
ACCESSION   DAXLPC010000209 DAXLPC010000000
VERSION     DAXLPC010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.217"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..1027
                     /locus_tag="ACF3UE_002829"
     CDS             <1..1027
                     /locus_tag="ACF3UE_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HFD3636143.1"
                     /translation="LTGNPKNIRLFLYNLFNSTEISFVELYTLPIIIKTEKMLKDLKQ
                     YYPLSAYEKKKLFHFLAINLLAEQADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFI
                     NKTLSWLYLHDKLDQKYLRKNEDETIEWLNERFIESFENQFNLLREETSQLIRRELTK
                     IHFKLLHYTINKADEFPLDVSFFRENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFS
                     YLLLLINHIPIQLISEPVKIIIDFSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPD
                     VIITNRNNLYEESASQVVVWLDPPRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPE
                     EIIDRIE"
     gene            complement(1081..>1215)
                     /locus_tag="ACF3UE_002830"
     CDS             complement(1081..>1215)
                     /locus_tag="ACF3UE_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3636144.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
BASE COUNT          427 a          179 c          208 g          401 t
ORIGIN      
        1 gttgacaggg aatcctaaaa acattcggct ttttttatat aatcttttta actcaacaga
       61 gataagtttt gtggaattgt atacgctacc tataattata aaaacagaaa aaatgttaaa
      121 agatttaaaa cagtattatc ctctgtctgc ttatgaaaaa aagaaattat tccacttttt
      181 agcaatcaac ctgttggctg aacaagctga ttctttagat attgctagca atcagtcgct
      241 atttttttcg gatataggat tttaccactt aaaaggagta ttaggagaaa aatccgttat
      301 ttttatcaat aagacactct cttggcttta tcttcatgat aaattggatc aaaaatactt
      361 gagaaaaaat gaagatgaaa caatcgaatg gttgaatgaa cgattcattg aaagttttga
      421 aaatcagttt aatctgttgc gagaagagac gagccaattg atccgaagag agttaaccaa
      481 aatacatttt aaacttttgc attacactat taataaagct gatgaatttc cacttgatgt
      541 ttcttttttt agagaaaact atccagcatt ttattgctat ttgatagagt atataaatga
      601 tctaacgtca aaacgcaaag agttgcttca agataaattt tttctttttt tcagttattt
      661 attattattg atcaatcaca tacccattca actgatttct gaaccagtaa agatcatcat
      721 cgatttttct tatggtgctg cctataatca atttatcaag aaaaatttaa gcttgtacat
      781 taatctgaac acggaagtga tagaggcagg aaagcctgag ttcccggatg ttataatcac
      841 gaataggaat aatctatatg aagaaagtgc atctcaagta gtggtttggc tcgatccgcc
      901 aagagcagta gactggggga atcttacaaa gattttgttg actatccaag aagagaaata
      961 caaagacagc aaaattgaca agcaaataga cgattttcct gaagaaatca tcgacaggat
     1021 cgaatagtga acttctttta gaaagtccga ctgctttttc taaaaatatt atttgtcaaa
     1081 ttaagcgaga caaaactttc catttacgta actcaaaaaa acttctaatg gtgtttggta
     1141 atttagtgat tttctaggga tatggtttct tttggacgca acggatgaga tgaatccttg
     1201 attgacttgg ttgaa
//
LOCUS       DAXLPC010000210         1208 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.218, whole genome shotgun sequence.
ACCESSION   DAXLPC010000210 DAXLPC010000000
VERSION     DAXLPC010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1208
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.218"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            2..1208
                     /locus_tag="ACF3UE_002831"
                     /pseudo
     CDS             2..1208
                     /locus_tag="ACF3UE_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          503 a          193 c          263 g          249 t
ORIGIN      
        1 catggcagaa gaaaaagaac cactagacaa tagtcgtttg ggaaaatcca aaagaaaatt
       61 agtacgattg caaaatgaat taaacgaaca aattgaaaag atgtttgaac accagagaaa
      121 gaccaacggt caaccaatga acgataagag aaatgggcat tcttggttta ggcaacaaga
      181 gcgaatcgaa aataaagtgc atagtctgag agaagagatc aagcaacaag aaaaacaagt
      241 agaaaaactt gaaagacaag aagagataaa ggaaatgggc tataacaagt acggcggact
      301 ggatatgacg atcgagaata ttccaagaat caaagaagaa atcgaacgct ttgaaaaagg
      361 tgaatcgact ttttcagccg ctacgatccg aaaataccaa cggaaattgg aaacattaga
      421 acagctgaaa gaaagatcgg aaaaaggaaa agaaaacctt cttcctgaag tacaagcaat
      481 cattgacagc ggacgagtga cgcaatggaa aaaaatccga ccatttattt tctgaaaggc
      541 tatcgaaaag tcgctttaga actgaatgaa aacggggaat ttgaggaatc taaaaaatac
      601 caagccacgt cggaagagga aaaagcagct gttcgtgaat tacttgaaga ggctgtacca
      661 actgattttt tgaaggagaa agaaaacgat catttttatc gagtagaatt caacgaaaat
      721 gatccagaaa aaggattgaa aagttatggt ggggagatcg taacattcga attgatcgat
      781 caactcaaaa cgttggataa ccaatacgcc gcagaagcag gttattataa attctatttt
      841 gaagaagtga agaacggaga agtagtcgat cagatccgaa tggatctagg ggatggcgtc
      901 aacagtaatc aacccatcta tttagagtta gcaaaattgt gcgaacaagt acctgagaag
      961 gaacaaaaac aatcggtcaa aaatgaacct gtttcgaaag aacaaatgca gtcgaaagaa
     1021 acaaaaacaa aacaaaaggg ctatcaaaaa cgaacggcag aagagattaa acaagaagtt
     1081 aaatcccttt cgcaacaggc actggatgcg gtgaaaaagc atactcattc tcctgaagac
     1141 gtcaaagaac ttttgaactt tatgtctcgt tttccagaac gatcctttag aaatcaatta
     1201 ttgattga
//
LOCUS       DAXLPC010000211         1186 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.219, whole genome shotgun sequence.
ACCESSION   DAXLPC010000211 DAXLPC010000000
VERSION     DAXLPC010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.219"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(188..1048)
                     /locus_tag="ACF3UE_002832"
     CDS             complement(188..1048)
                     /locus_tag="ACF3UE_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFD3636145.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT          360 a          225 c          174 g          427 t
ORIGIN      
        1 atttgatggt taacctactt aaaataaata ctgcaacgac aaacggagat caagcatgct
       61 ttgtaacgta ttttacgata attacgactt tattttatta ctctatcttg ctgccatacc
      121 cgtctatccc taatcatctt tggtgaattt tttcaaagtt agcataacaa aaataagtat
      181 tttttcctta gttaatcaat agtatcattt ttttcatatg atttaattca tcaattaatt
      241 ttttgttttt attaatttta gcaaaagcta gtgcatcttg aatcaattcg agcacttctg
      301 ccttcgactt atttttagcc tgtgcgttct tcgctaattg ggcagcagct cgtgctaagt
      361 aataagtcaa atggttatcc gaacaaatat cgattgcgta atttagtagt gcatcacttg
      421 tttccaaatc accgtcttgc gcaaaaaaaa caccacaatg aaagacgata tttaacaccc
      481 gccagatatc ttctgttgta cgaatcggat acgtataaat tttttcaaac actcgattga
      541 aataaacttc tgctttttcc aactcttttt ctctagcata gaccattcca atacctgtat
      601 atgccaataa acgaaacaac gtgttggctg tttctgccat caacaactga tcaaaatgga
      661 acaacacatc cgtaattggt gcattcgtaa aaatcatttc aaatcctttt agatagtagt
      721 aacgtgcaat cagctcagac tcgtcaatta ccttgggatc aatggctgct aaaatctgtg
      781 tcaattgttc atattcactc gtaatcagtg aaaactctgc tttttctagc tgttcatcaa
      841 gttgtgtatt gatcacgttc atcgaagaaa aaagttcaac taacggaaga ttgattcgat
      901 tacataattt gattaaaatt tttaacgaag ggacttgacc attgttctca aatttactta
      961 atgttgcttg tgtacaaatt ccttcagaca cttctttttg agataagttg gcagcctttc
     1021 ttgccgtaat aaatttttca atgttcatta ttttctctcc aatcagacct cacacgaaaa
     1081 tcatttctgt ctcgatttta gcatgttttc tttgggaatg ctttaggttc tgttgcaaag
     1141 ttttaaataa agaataaagt cccttacggt atctatgatt taagct
//
LOCUS       DAXLPC010000212         1155 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.221, whole genome shotgun sequence.
ACCESSION   DAXLPC010000212 DAXLPC010000000
VERSION     DAXLPC010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1155
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.221"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>1155
                     /locus_tag="ACF3UE_002833"
     CDS             <1..>1155
                     /locus_tag="ACF3UE_002833"
                     /inference="COORDINATES: protein motif:HMM:NF021909.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFD3636146.1"
                     /translation="TVTTTYYDQSKNVSDQLTNINISISNNKEKVIFPHNAESLTSNY
                     AFKVPDSVNPKDYFYIDLSENANFYGVTEANSVTMPNLLAPDNSIIATGKYDIDTNRI
                     QYEFTDYVAVHDNVSGKISLPIFIDPEVVTNTSYQTITASIGNSKKDLSLLVDYSKNV
                     GPQYNANGAGNIFNVDLNNHNFSHTIYVNSLKQTLGNKSIEIRNQRKEENGYNSEIIY
                     DKTNTQIKVYKVKSNGRLTDSFSIATNDSLEDVTNQCYIDFYDNKINISFPSNIDNET
                     YVVQYTSPYTDKKDIATRVVMYGYSPYQLGNTSWYWDNYVKLTDGNASGDGSVISPDP
                     ETPVTPETPDPETPVTPETPDPETPVTPETPDPETPVTPETPDPETPVTP"
BASE COUNT          440 a          192 c          175 g          348 t
ORIGIN      
        1 aacagtaact actacttatt atgaccaatc taaaaatgtt agtgatcaat taacaaatat
       61 taatatttca atatctaata ataaagagaa agtcatattt ccacataatg cagaatcgct
      121 aacttcaaat tatgcattca aagtccctga ctcagttaat ccaaaagatt atttttatat
      181 tgacttgagt gaaaatgcta atttttatgg agttacagaa gctaactctg tcacaatgcc
      241 taatctctta gctccagata attcaattat agcaactgga aaatacgata ttgatactaa
      301 tcgtattcaa tacgaattta cggattatgt agcagtgcat gataatgtta gtggaaaaat
      361 ttctttaccg atctttattg atccagaagt agtaactaat acttcttatc aaactattac
      421 tgcgagtata ggcaatagta aaaaagattt gagtctgtta gtggattatt ctaaaaatgt
      481 aggacctcaa tataatgcta atggtgctgg taacatattt aatgtagact tgaataacca
      541 taatttttct catactatct atgtcaattc tttaaaacaa actttaggaa ataaaagtat
      601 tgaaattaga aatcaaagaa aagaagaaaa tggatataat tctgaaatta tctacgataa
      661 gacaaatact caaataaaag tttataaagt aaaatcaaac ggaagactaa ccgacagttt
      721 ttctattgct acaaatgatt cactagaaga cgtgactaat caatgctata ttgattttta
      781 tgataataaa attaatatta gttttccgag caatattgat aacgaaactt atgtcgttca
      841 atatacttct ccttatacag ataaaaaaga tattgctact agagtagtta tgtatggtta
      901 ctctccttat caattaggca atactagctg gtactgggat aattatgtaa aactaacaga
      961 tggaaatgca agtggtgacg gtagtgtgat atcacctgat ccagaaactc cagtaacgcc
     1021 agagactcca gatccagaaa ctccagtaac accagagact ccagatccag aaactccagt
     1081 aacgcctgag actccagatc cagaaactcc ggtaacgcct gagactccag atccagaaac
     1141 tccagtaacg ccaga
//
LOCUS       DAXLPC010000213         1141 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.222, whole genome shotgun sequence.
ACCESSION   DAXLPC010000213 DAXLPC010000000
VERSION     DAXLPC010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.222"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..378)
                     /locus_tag="ACF3UE_002834"
     CDS             complement(<1..378)
                     /locus_tag="ACF3UE_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFD3636147.1"
                     /translation="MRKWKVVVGSLGILIALFILGACSTNSKDKVASNEKLKVVVTNS
                     ILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGGNA
                     WFTKLVKNANKEENKDYFAASDGI"
     gene            complement(378..>1141)
                     /locus_tag="ACF3UE_002835"
     CDS             complement(378..>1141)
                     /locus_tag="ACF3UE_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFD3636148.1"
                     /translation="VSGTVGCFIILRGMSLMGDAISHAVLPGVAISYILGINFFIGAI
                     VFGLLASIIITFIKSNSVIKGDTAIGITFSSFLALGVILIGVANSSTDLFHILFGNIL
                     AVQDIDKWITIGVSVLVLVIVVLFFKELLITSFDPLMAKAMGMNVNFYHYLLMVLLTL
                     VAVTAMQSVGTILIVAMLITPAATAYLYANSLKTMIFISAAVGASSSLLGLFIGYNFN
                     IAAGSSIVLTAASLFVISFLISPKQKFLRKKERSL"
BASE COUNT          412 a          223 c          140 g          366 t
ORIGIN      
        1 tatgccatca cttgctgcaa aatagtcttt gttttcctct ttgttcgcat ttttaactaa
       61 ttttgtaaac caagcatttc ctccagtttc caagttaaca ccattataaa aaatcaagtc
      121 tgcttttgaa gttttttgaa catcttcagg caaaggttca tattcatggg gatctttccc
      181 aataggtaca atactgtgta aatcaatttt atcctttgct atattttcag taatatctgc
      241 taaaatcgaa ttagtaacta ctacttttaa tttttcgttc gaagccactt tatctttact
      301 atttgttgaa cacgctccta atataaaaag agcaatcaaa atccccagac ttcccactac
      361 tactttccat tttctcatca taacgatctc tccttctttc ttaaaaattt ttgttttggt
      421 gagattagaa aactaattac aaataaggat gccgctgtta aaacaatact tgatcctgcg
      481 gctatgttaa aattataacc aataaacaat ccaagcaatg atgagcttgc cccgactgct
      541 gcagaaataa atatcatagt tttcaagcta tttgcatata aatatgctgt agctgctggc
      601 gtgattaaca ttgcaacaat taatatagtc cccacacttt gcatagctgt tactgctact
      661 aaagttaata gaaccatcag tagataatga taaaaattga cgttcatccc cattgctttt
      721 gccattaatg gatcaaaaga agtaattaat aattctttaa aaaatagaac tactataacc
      781 aacactaaaa cagaaacgcc aatcgtaatc cacttatcaa tatcttgtac agctaaaatg
      841 tttccaaata agatatgaaa taaatccgtt gagctatttg caactcctat aaggataact
      901 cctagcgcta aaaaagaact gaaagtaata ccaattgctg tatctccttt tattacacta
      961 ttgcttttta taaaagtaat aatgatagaa gctaatagac caaatacaat agcaccaata
     1021 aaaaaattaa tacctaaaat ataagaaatt gctactcctg gcaaaacagc atgagaaata
     1081 gcatcgccca taagagacat tcctcttaaa ataataaaac aacctactgt tccagaaaca
     1141 a
//
LOCUS       DAXLPC010000214         1134 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.223, whole genome shotgun sequence.
ACCESSION   DAXLPC010000214 DAXLPC010000000
VERSION     DAXLPC010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1134
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.223"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..232
                     /locus_tag="ACF3UE_002836"
     CDS             <1..232
                     /locus_tag="ACF3UE_002836"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3636149.1"
                     /translation="CKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFY
                     HNCGFKIGSVDTMLYANFENNFEKAVFWYLRF"
     gene            325..1119
                     /locus_tag="ACF3UE_002837"
                     /note="aph(3')-IIIa"
     CDS             325..1119
                     /locus_tag="ACF3UE_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFD3636150.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          359 a          191 c          286 g          298 t
ORIGIN      
        1 atgtaaggat ttcagggggc aaggcatagg cagcgcgctt atcaatatat ctatagaatg
       61 ggcaaagcat aaaaacttgc atggactaat gcttgaaacc caggacaata accttatagc
      121 ttgtaaattc tatcataatt gtggtttcaa aatcggctcc gtcgatacta tgttatacgc
      181 caactttgaa aacaactttg aaaaagctgt tttctggtat ttaaggtttt agaatgcaag
      241 gaacagtgaa ttggagttcg tcttgttata attagcttct tggggtatct ttaaatactg
      301 tagaaaagag gaaggaaata ataaatggct aaaatgagaa tatcaccgga attgaaaaaa
      361 ctgatcgaaa aataccgctg cgtaaaagat acggaaggaa tgtctcctgc taaggtatat
      421 aagctggtgg gagaaaatga aaacctatat ttaaaaatga cggacagccg gtataaaggg
      481 accacctatg atgtggaacg ggaaaaggac atgatgctat ggctggaagg aaagctgcct
      541 gttccaaagg tcctgcactt tgaacggcat gatggctgga gcaatctgct catgagtgag
      601 gccgatggcg tcctttgctc ggaagagtat gaagatgaac aaagccctga aaagattatc
      661 gagctgtatg cggagtgcat caggctcttt cactccatcg acatatcgga ttgtccctat
      721 acgaatagct tagacagccg cttagccgaa ttggattact tactgaataa cgatctggcc
      781 gatgtggatt gcgaaaactg ggaagaagac actccattta aagatccgcg cgagctgtat
      841 gattttttaa agacggaaaa gcccgaagag gaacttgtct tttcccacgg cgacctggga
      901 gacagcaaca tctttgtgaa agatggcaaa gtaagtggct ttattgatct tgggagaagc
      961 ggcagggcgg acaagtggta tgacattgcc ttctgcgtcc ggtcgatcag ggaggatatc
     1021 ggggaagaac agtatgtcga gctatttttt gacttactgg ggatcaagcc tgattgggag
     1081 aaaataaaat attatatttt actggatgaa ttgttttagt acctagattt agat
//
LOCUS       DAXLPC010000215         1133 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.224, whole genome shotgun sequence.
ACCESSION   DAXLPC010000215 DAXLPC010000000
VERSION     DAXLPC010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.224"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>1133
                     /locus_tag="ACF3UE_002838"
     rRNA            <1..>1133
                     /locus_tag="ACF3UE_002838"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          290 a          256 c          350 g          237 t
ORIGIN      
        1 agagaatcct aaggtgagcg agagaactct cgttaaggaa ctcggcaaaa tgaccccgta
       61 acttcgggag aaggggtgct gatcatacga tcagccgcag tgaataggcc caagcgactg
      121 tttatcaaaa acacaggtct ctgcaaaatc gtaagatgaa gtataggggc tgacgcctgc
      181 ccggtgctgg aaggttaaga ggagtgctta gcgcaagcga aggtacgaat tgaagcccca
      241 gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt cgggtaagtt
      301 ccgacccgca cgaaaggcgt aacgatttgg gcactgtctc aacgagagac tcggtgaaat
      361 tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc atggagcttt
      421 actgtagttt gatattgagt gtctgtaccg catgtacagg ataggtagga gccgtagaaa
      481 tcggaacgct agtttcgatg gaggcgctgg tgggatacta cccctgcgtt atggccactc
      541 taacccgcac cactaatcgt ggtgggagac agtgtcagat gggcagtttg actggggcgg
      601 tcgcctccta aaaggtaacg gaggcgccca aaggttccct cagaatggtt ggaaatcatt
      661 cgaagagtgt aaaggcagaa gggagcttga ctgcgagacc aacaagtcga gcagggacga
      721 aagtcgggct tagtgatccg gtggttccgc atggaagggc catcgctcaa cggataaaag
      781 ctaccctggg gataacaggc ttatctcccc caagagtcca catcgacggg gaggtttggc
      841 acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt tgggctgttc
      901 gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc ggtccctatc
      961 cgtcgcgggc gttggaaatt tgagaggagc tgtccttagt acgagaggac cgggatggac
     1021 ttaccgctgg tgtaccagtt gttctgccaa gggcattgct gggtagctat gtagggaagg
     1081 gataaacgct gaaagcatct aagtgtgaag cccacctcaa gatgagattt ccc
//
LOCUS       DAXLPC010000216         1106 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.225, whole genome shotgun sequence.
ACCESSION   DAXLPC010000216 DAXLPC010000000
VERSION     DAXLPC010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.225"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..330
                     /locus_tag="ACF3UE_002839"
     CDS             <1..330
                     /locus_tag="ACF3UE_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3636151.1"
                     /translation="DFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLTNIENKGQQP
                     SFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVTIGKVIQAIY
                     GEKCKFN"
     gene            complement(844..1011)
                     /locus_tag="ACF3UE_002840"
     CDS             complement(844..1011)
                     /locus_tag="ACF3UE_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFD3636152.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITV
                     ITEPDAKTQSR"
BASE COUNT          365 a          164 c          188 g          389 t
ORIGIN      
        1 gatttcaaac cattgggtct tgcgattaaa gaagcccgtc ttagtaaagg attgactcgt
       61 gagcaggtag gatcaatgat ccagattgcg ccacgctatt tgacgaacat tgaaaataaa
      121 ggacaacagc caagttttca tgttgtatat gatttagtga ctttgctaaa tatttctttg
      181 gatggattta ttttagggga agaaaacagt cataaaagct ccaaacgtct tcaagtagaa
      241 gcacagttgg attgtctgga tgaagatgaa ttagtgacga ttgggaaagt gattcaagca
      301 atttacggag aaaaatgtaa atttaactag ttcaataata cacaatggat taattaatac
      361 tatcaggaaa gattgattac aaagatgtaa tgaatttttt ctgatttttg ttaatcataa
      421 atagaaaatg aatttatctt tgttacactt aggaactaga gcgaatgata aatagttctt
      481 tggttactct tatcgctgca aagtacagtt cattttttgt tgttgggaaa attttctgga
      541 tttattgcat atcacttcat ccgactaaaa atttttgatt cccatagcga agttcgtttt
      601 tgttccttag gaaaaacttg actgatatac tagttttgaa atgacgagta actctgtact
      661 tcatcaataa tcaagtattg aattttaatt gtatactttt tatgcttgag ggatgtctac
      721 tgtaatacag ctactgcaaa aaaaatcagt acacttattt tcttataaag gatatcaaga
      781 actaagctca atggtatgca tagaaaagaa aaagccgata aaatgagatt ttgatatctc
      841 gaattatcgg ctctgcgtct ttgcgtctgg ctctgtaatt acagttattc taaacttcgt
      901 tatttcaatt aaaatttctt gtctgcattt aggacaaaat agagggaaat tttttaattc
      961 agtatcttcc ctcattttta aacgggtctt attgccacat atagggcaca gtatccacct
     1021 agtatttaca atatctatat cctcctgttc taattaacaa ctcaatattc attttaaaaa
     1081 tttctcttta gttcactatc aatgta
//
LOCUS       DAXLPC010000217         1097 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.226, whole genome shotgun sequence.
ACCESSION   DAXLPC010000217 DAXLPC010000000
VERSION     DAXLPC010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.226"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..224
                     /locus_tag="ACF3UE_002841"
     CDS             <1..224
                     /locus_tag="ACF3UE_002841"
                     /inference="COORDINATES: protein motif:HMM:TIGR01167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3636153.1"
                     /translation="TPETPDPETPVTPETSNYKTLQIQKSKVNYKSETNKTLPKTGEA
                     KSSGVFVGIIVLLTSIFAGFKLNLKRKKG"
BASE COUNT          438 a          114 c          163 g          382 t
ORIGIN      
        1 taacacctga gactccagat ccagaaaccc cggtaacgcc agagactagt aattataaaa
       61 ctctacaaat acaaaagagt aaggtgaatt ataaatctga aacaaataaa actcttccaa
      121 aaactggaga ggcaaaatca tctggagtat ttgtaggtat aatagtttta ttgacttcta
      181 tttttgctgg atttaaatta aatttgaaaa gaaaaaaagg atagaaaata gatctgagat
      241 agaatactta gtgttctatc tcaggttgta attatgtttt atatcactca agtattaagg
      301 agggattatg ataactttag aagagaaata tatataatct ttaggcaaga aatgtataag
      361 aaaagagtct atttaaatca taagtatatt caagatactg aatctcacgc ccaatgttta
      421 atatgcttgg ccgaaaaaac gtattatatt attcattatt cagaaatact tattggttga
      481 ttttttattt tttctaggga caaagacttg taattaaaga aacaggaaat aaaaaacgaa
      541 aaattaagtc ttctttaaca aaaaaaacat tggaagataa gaaattttca atagaaaaat
      601 ctcatctctc aaaaaaaata ttatatacaa tcgaaaaaaa ttttttatat cgatgatagt
      661 aattttttgt ctagtggatt aaataatact agtgtgaatt ttcaaatatt gttagttaat
      721 agtttttatg gtttctaaaa ggattggagg taagaaataa tatgtttgtg agataagaat
      781 cattatttag tacatcttct tataagcagg gaacttattt ctagaattaa aaaacttgta
      841 taaaaaataa attgaacatt catttttatt tgacttgagg atttttactt gataatatta
      901 tatcgtaaac tattttaatt tataaagtga acagtctatt tttttataca agttactcac
      961 tttgatagtt tcagatatag taattggtta aacttatcgt attagtttaa ctaaagttag
     1021 tgagataaat gaaatgaaag gagaatattc tagaaatcaa actgccaaaa tctgtgtcaa
     1081 gtttaattta taggttt
//
LOCUS       DAXLPC010000218         1089 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.227, whole genome shotgun sequence.
ACCESSION   DAXLPC010000218 DAXLPC010000000
VERSION     DAXLPC010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1089
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.227"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            4..978
                     /gene="bsh"
                     /locus_tag="ACF3UE_002842"
     CDS             4..978
                     /gene="bsh"
                     /locus_tag="ACF3UE_002842"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFD3636154.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          382 a          135 c          187 g          385 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagttact gttactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tgggctaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaaactaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgatgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg ttggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattgatatg
      901 aataaagaag acttagatag tcataagtta attagttatc caattataga aaaacaacaa
      961 attaaatata taaattagtt aatgtgttgt gattgattat ttaatataga tataatacaa
     1021 aaaggcaaag atattttcaa aacatttttt cttgatgtga tatccttgtc ttttttgtaa
     1081 tgtttttaa
//
LOCUS       DAXLPC010000219         1081 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.228, whole genome shotgun sequence.
ACCESSION   DAXLPC010000219 DAXLPC010000000
VERSION     DAXLPC010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1081
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.228"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            118..1014
                     /locus_tag="ACF3UE_002843"
     CDS             118..1014
                     /locus_tag="ACF3UE_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFD3636155.1"
                     /translation="MIQYYYIKKEWGVVMEKEELKILEELRRILNSKNEAIVILNNYF
                     KGGVGKSKLSTMFAYLTDKFNLKVLMIDKDLQATLTKDLAKTFKVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMLERIIQLENEKE"
BASE COUNT          414 a          155 c          178 g          334 t
ORIGIN      
        1 tctttttcaa aataaacata aaagcccttt aaagagggct tttatatatt aatcacaaat
       61 cacttatcac aaatcacaag tgattaatca caaatcactt gtgatttgtg attcctaatg
      121 atacaatatt actatataaa aaaagaatgg ggcgtagtta tggagaagga agaactaaaa
      181 atacttgaag aattaagacg tattttaaac agtaaaaatg aagcaattgt tatcttaaac
      241 aattatttta aaggtggtgt tggaaagtca aaattatcga ctatgtttgc ttatttgaca
      301 gacaaattta atttaaaagt tttaatgatc gataaggact tacaagcaac attgacaaaa
      361 gacttagcaa aaacatttaa ggtagaattg ccacgtgtca atttttatga aggcttgaaa
      421 aatggaaact tggcttcttc tattattcat ttgactgata atttagactt gatccctggc
      481 acgtttgatt tgatgttact gccaaaatta actcgctcat ggacgtttga aaacgaaagt
      541 agattgcttg ctactctttt agcaccttta aaaagtgact atgatctcat tattattgat
      601 actgtaccaa cgccaagcgt ttatacaaat aatgcaatcg tggcaagtga ttacgttatg
      661 atccctttac aagcagaaga agaaagtaca aacaacattc aaaactatat ttcctatttg
      721 attgatttac aagaacagtt taaccctgga ctagatatga tcggttttgt tccttattta
      781 gttgatacgg acagcgcaac gataaaatca aacctggaag aactgtacaa agaacataaa
      841 gaggataatt tggttttccg aaatattatc aagcgaagta ataaagtaag tacctggtct
      901 aaaaacggca ttacagaaca caaaggctat gacaaaaaag ttttatctat gtatgagaac
      961 gtattttttg aaatgcttga gcgaatcatt caattagaaa acgaaaaaga atagaatcac
     1021 aaatcacaag tgattaatca caaatcactt gtgatttgtg attgttgatg ataaaataag
     1081 a
//
LOCUS       DAXLPC010000220         1068 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.229, whole genome shotgun sequence.
ACCESSION   DAXLPC010000220 DAXLPC010000000
VERSION     DAXLPC010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.229"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..490)
                     /locus_tag="ACF3UE_002844"
     CDS             complement(<1..490)
                     /locus_tag="ACF3UE_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFD3636156.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVY"
     gene            complement(550..759)
                     /locus_tag="ACF3UE_002845"
     CDS             complement(550..759)
                     /locus_tag="ACF3UE_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636157.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            complement(826..1065)
                     /locus_tag="ACF3UE_002846"
     CDS             complement(826..1065)
                     /locus_tag="ACF3UE_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636158.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
BASE COUNT          293 a          239 c          140 g          396 t
ORIGIN      
        1 gatagacgcc atcgttacta actaagtcca tcacctcccc taatgacaac ttttgaatat
       61 cagaaaataa aacacctggc atttccatgt tatgacctgc taggacatag tttcctttgc
      121 ccatttcggc atcttcataa aaataagtag ccgctccaag actcaaagtg tattgatttg
      181 cccctttaaa aattggcaat gctaaaccaa gtgcaggaat ctgaatttgt gcaaatactt
      241 gtttattgac gcccatttcg attgcttctt tttgtatgga caacatttgc cccaaagaca
      301 tatcattatt gacgttcgtt gcatcctcct tataactctt tgcatgtgca ttgatttgat
      361 ctacgggcat ctttttttct atattttgct taaacacctc tccttcatgt ttttggtagc
      421 taacatagcc aaacacactg caaaagacga ttaaagtgac tcctaaaaaa ccaaataacc
      481 attttttcat ccatctgcct cctttcagac aaaacaaaaa aactttttct catttccata
      541 gaaaaagttt taaaaatgaa ttctataagt tcgtctcaac tgttcaaagt ttttcattga
      601 acctaacaaa caagctttct cttttcctgt taactgcata tcattgatat attgcgcgac
      661 agataatctt ttaaggtgtt tttgcttcat cgtttttagt aacttttctt ccatttcttt
      721 cgacactttt tttctgtttt cgatttcttc ataattcatg agttttccta ccttccttgt
      781 tttttgcaaa aataaaaaag cctatgatca catacgctct acacttcagt cttgggttat
      841 ctttttcttt cgtttaatta ctggccgtgc tggtttcaaa tccttgattc cattatgggt
      901 tctccaataa tcgaattctt ttcgcaatct ttctttttcc atatctgttc ctttagataa
      961 ggctttgaat acttctttag gtgaataacc acgagctaac agctgtacat accttccttt
     1021 tgtcaaagta tccatatcca tcgcctctaa aactggtcgc gccatcta
//
LOCUS       DAXLPC010000221         1055 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.230, whole genome shotgun sequence.
ACCESSION   DAXLPC010000221 DAXLPC010000000
VERSION     DAXLPC010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.230"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            27..146
                     /locus_tag="ACF3UE_002847"
     CDS             27..146
                     /locus_tag="ACF3UE_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFD3636159.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            complement(394..942)
                     /gene="aac(6')"
                     /locus_tag="ACF3UE_002848"
     CDS             complement(394..942)
                     /gene="aac(6')"
                     /locus_tag="ACF3UE_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFD3636160.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          307 a          224 c          157 g          367 t
ORIGIN      
        1 aaaaatagct ttgtacaagg ttttccatgg tcttccaaaa gccattaaat aattttcgtt
       61 atattgtcta ttattgccat acaaagataa aaaagaataa acaaaaagaa actgtgacaa
      121 aagtcttgtc acagtccctt atctgaataa acggtgttca aaagccagtt tctcggtatt
      181 aagccaaatt tatgcaaaaa tgtagaaagc cattttcaca aaatttttct tactactcga
      241 aactaagcga ctttttcaca acctctggta cacggtgttc caaaagtagc ttcttcggaa
      301 ataagttgga atttcacaaa aattcaagaa gtaattttcg taaattcctt cttatttctt
      361 gaagctgatt acttctgtca caacctcttt ttattattga gaatttggtc gaggaataat
      421 cgtttttgcc atccaaatat ccggtttgtc ccagccattt gcatttggta agacacctac
      481 gattttataa cctaattttt catagaattc atacggatgt tcacgaaggt tctggatgga
      541 agccacttta tcaaatgtat gctcatacag gtccgtttga cttaacgttg ttccatggtc
      601 taaatcatcc gtacctaaat aaatcgtgat tcctcctctg gaagctactt ctttttctaa
      661 gtaattgact aatcgagtac ctatttggtt ctttcgtcgg gagctttcta caactaatgg
      721 atgcaattcc caacctgtga taccgtattg agggattgca ccaataaatc ctactaactc
      781 atcttggtct accgctgcta ccgcgattcg ttctggattc atcatttctt ctacttcttc
      841 tgccgagctg tctccatatt cttccggcca agtcagtctc agtaaatcag aaagctgatc
      901 tttcaatact ggattattac ggtcaaattc actgattatc atacgtcttc ccccttgttc
      961 ttgcttattc taacagtcct tttgaaaaaa cgaaatgttc tcgctcaaaa atctttagct
     1021 accaatcagt atctctattc tttcattatt tatct
//
LOCUS       DAXLPC010000222         1032 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.231, whole genome shotgun sequence.
ACCESSION   DAXLPC010000222 DAXLPC010000000
VERSION     DAXLPC010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.231"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            38..>1032
                     /locus_tag="ACF3UE_002849"
     CDS             38..>1032
                     /locus_tag="ACF3UE_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFD3636161.1"
                     /translation="MHKISVIVPAYNVEDYLENCLESISNQTHSNIEIIVVNDGSPDR
                     SGEIAEEYKKKDMRLKVIHQVNGGLSAARNSGLDSATGDFVCFIDSDDWIEPDYLELL
                     YFGTQTYGADISVLKIKKISSLEQLKEHTIAERKWEIFDREQAMKNLFINNKIGYSAN
                     NKLFNRNLFDNIRFPLGKLMEDKATTYLLIDHSEKVAVNSSAKYHYYQSPKSILRGSF
                     NPRIFDSFEVHEDILIFIDKFYPELSINVRTRYVYEAIRMMMTMIKNNYTNKEDYLRS
                     INILQRFEKEVKIDPDFSPKLKKLVKFLLINKNLPYYMSSSKIASKFLIKIESVR"
BASE COUNT          409 a          129 c          179 g          315 t
ORIGIN      
        1 taaaaataaa aaagatgatt tttaggaagt gaagagagtg cataaaatta gtgttatagt
       61 acccgcatat aacgtagaag actatttaga aaactgctta gaatctattt ccaaccagac
      121 acattcaaat attgaaataa tagtagtcaa tgatggttcc ccggatcgaa gtggggaaat
      181 tgcagaagaa tataaaaaga aagatatgcg attaaaagtg atacatcaag tgaatggtgg
      241 tttaagtgcg gctaggaatt ctggtcttga ttctgcaaca ggagattttg tgtgctttat
      301 tgacagcgat gattggatag aaccagacta tcttgagtta ctatattttg gcacgcaaac
      361 ttatggagca gatatctcgg tgctaaaaat aaaaaagatt tcaagtttag aacaactaaa
      421 agaacataca attgctgaga gaaaatggga aatatttgat agagaacaag caatgaaaaa
      481 cttatttata aataataaaa ttggctattc tgcaaataat aaattattca atagaaattt
      541 atttgataat ataagattcc cactgggtaa attaatggaa gataaggcta ctacttattt
      601 gctgatcgat cattccgaaa aagttgctgt caattcatct gctaaatatc actattacca
      661 aagccctaaa agtatactga gaggaagctt caatcctaga atttttgatt cttttgaagt
      721 ccatgaagat atactaatat tcatagataa gttttatccg gaattatcaa ttaatgttag
      781 aactcgctat gtctatgaag caataaggat gatgatgaca atgattaaaa ataactatac
      841 caataaagaa gattatttac gttctataaa tattttacaa cgctttgaaa aagaagtgaa
      901 aattgatccc gacttttcac caaaattaaa aaaattagta aagtttttat taataaataa
      961 aaacttgcct tactatatgt caagtagtaa gatagcaagt aaattcttga ttaagataga
     1021 atctgtgagg ta
//
LOCUS       DAXLPC010000223          970 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.232, whole genome shotgun sequence.
ACCESSION   DAXLPC010000223 DAXLPC010000000
VERSION     DAXLPC010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.232"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            136..309
                     /locus_tag="ACF3UE_002850"
     CDS             136..309
                     /locus_tag="ACF3UE_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636162.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
BASE COUNT          332 a          151 c          118 g          369 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat
//
LOCUS       DAXLPC010000224          966 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.233, whole genome shotgun sequence.
ACCESSION   DAXLPC010000224 DAXLPC010000000
VERSION     DAXLPC010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..966
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.233"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..>966)
                     /locus_tag="ACF3UE_002851"
     CDS             complement(<1..>966)
                     /locus_tag="ACF3UE_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3636163.1"
                     /translation="LHFYKASYNYHLIDFMYKYPRSVLKDFAKEQFTSVSTVFRYAKL
                     LIPYFRRYHITFHPFQLELNASEANIRSFFYYFYWNSTRESSDKWPFHIEQKEIEKYI
                     VAFEGIYDITLTIFQKRVFSFWLAINIERSSFRKVRVDNEYKSVISDDPHFNLLKKWS
                     KQINLSFNSDELCFLYRIIYSFGVIDGNAIYENSHAYAHQRQNTCSYRAVENLEKVLQ
                     SMFRFSLDIKDPELIFNFIAFHERSYLFYGNPDLFFNRSYIEEMKEEEPRTYHIMEKL
                     KKELQANADLDVSKKLENWAQLFLDYYYVLDYYDLFLTNVKPIKI"
BASE COUNT          359 a          154 c          119 g          334 t
ORIGIN      
        1 aaaatcttaa tcggtttaac atttgttaaa aataaatcat aataatctaa cacataataa
       61 taatccaaaa ataattgtgc ccagttttct aatttctttg atacatccaa atccgcattt
      121 gcttgtaatt cttttttgag tttttccatt atgtgataag ttcgaggttc ttcttctttc
      181 atttcttcga tatacgaacg attaaaaaaa agatctggat taccataaaa tagataactt
      241 ctttcatgaa atgcaataaa attgaatatg agttctggat cctttatatc taaagaaaaa
      301 cggaacatgc tttgtaaaac tttctccaaa ttctcaactg ctcgataaga acaagtattt
      361 tgtcgctgat gtgcatatgc atgactattt tcatatattg catttccatc aattactcca
      421 aaagaataaa ttattcgata aaggaaacac agttcatcgc tgttaaaaga aagattgatt
      481 tgttttgacc acttcttcaa aagattaaaa tgcggatcat ctgagataac tgatttatat
      541 tcattatcta ctcgtacttt tctaaatgaa cttctttcta tattaatggc taaccaaaaa
      601 gaaaatacac gtttttgaaa aatagttaac gtaatatcat aaatcccctc aaaagcaact
      661 atatacttct ctatttcctt ttgttcgata tgaaatggcc acttatcact actttcacgt
      721 gtagaattcc aatagaaata ataaaaaaag ctacgaatgt ttgcctctga tgcattcaat
      781 tctaactgaa atggatgaaa tgttatatga taacgcctaa aatatggaat taagagcttc
      841 gcatatctga aaacagtaga tacactagta aattgctctt tagcaaaatc ttttagaaca
      901 cttctaggat atttatacat aaaatcaatc aaatgataat tataagaagc tttataaaaa
      961 tgaaga
//
LOCUS       DAXLPC010000225          949 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.234, whole genome shotgun sequence.
ACCESSION   DAXLPC010000225 DAXLPC010000000
VERSION     DAXLPC010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.234"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            38..>949
                     /locus_tag="ACF3UE_002852"
     CDS             38..>949
                     /locus_tag="ACF3UE_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3636164.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPME"
BASE COUNT          341 a          173 c          182 g          253 t
ORIGIN      
        1 atagttccga cgaaagaatt ataaggagtg agtacaaatg acctataacc atcttacacc
       61 aactgaactc gtaatgatag aagcttattt caatcaatca caacctgttt caaaagtagc
      121 caatctgtta caacgttctc gacaaactat ttataaggtc tatcgttttc ttaaatctgg
      181 tggaagcgca atgagctact ataaacaata taagaaaaac aaacgtaact gcggaagaca
      241 tccgattgtt ttacctgatg agcaacagga atacattcaa aaaaaggttg ttcaagggtg
      301 ggctcctgat gtccttattg gtcgagcaga gtttcctatt gcttgttcgg tacgcacact
      361 gtatcgaatg tttaaagata aaacctttga cactcacgat ttaccaatga agggaaaaag
      421 aaaaccaaac ggtcataaag aaaaaagagg aaaacaaggg tttcgccggt caatccgaga
      481 cagaaagaca gactataccc agtttgatca tgaatttggt cacctggaag gtgacactat
      541 cgtgggtgga aaacataaaa gcgcggtcat cacattagtt gaacggctat ctaaagtcat
      601 cattaccttg aaacccgaag gcagacaggc taaagacatt gaaaataggc tgaatcaatg
      661 gtttcgttgt gtcccaaaaa acttatttaa atccatcaca tttgattgtg gaaaagaatt
      721 ctcaaattgg aaaaagatta gtaataccaa cgatatttca atttattttg cggatccagg
      781 aacaccttct caacgaggat tgaatgaaca ttcaaatggc ttattacgta aagatggttt
      841 gtataaagct atggatttta atggtgtatc tgaaaccttt atccaatcgg tggcatcgaa
      901 acgaaatcat attcctagaa aatcattaca ctatcggaca ccaatggaa
//
LOCUS       DAXLPC010000226          924 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.235, whole genome shotgun sequence.
ACCESSION   DAXLPC010000226 DAXLPC010000000
VERSION     DAXLPC010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.235"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..113
                     /locus_tag="ACF3UE_002853"
     CDS             <1..113
                     /locus_tag="ACF3UE_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFD3636165.1"
                     /translation="QYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            143..265
                     /locus_tag="ACF3UE_002854"
     CDS             143..265
                     /locus_tag="ACF3UE_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFD3636166.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            283..>924
                     /locus_tag="ACF3UE_002855"
     CDS             283..>924
                     /locus_tag="ACF3UE_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HFD3636167.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGY"
BASE COUNT          371 a          136 c          196 g          221 t
ORIGIN      
        1 ttcaatacac cactcgacaa aaagaccaaa ccactattat tctaatcgga aaaatgttgg
       61 atgaagaaag gatcaaacag agttttgata aattactggc ggaaagcaaa taatgataag
      121 tagtgattgg gggtaatttc taatggagaa aacggatata tctagtgcat atcgacgact
      181 taaaagcccg aatattaaaa ctagaaaaag ggcattaaaa attatcaaag aacataaacg
      241 aaataaaatg aagaaattag cataattaag gaaggaaaaa gaatgaagaa aatcagtgta
      301 ggacttattg ggatagcagc tctaggatta ttgggagctt gctccagcac taatgatgca
      361 aaagtatcga atgataaaga tggaaaatta gaaattgtaa caacattcta tccaatgtat
      421 gatttcacca aaaacatcgt cggcgatgaa gcgaacgtgg atttaatggt tccagcggga
      481 tcagaacctc atgactatga gccctcagct aaggatatgg caaaagctca tgatgctgat
      541 gtttttgtat atcataacga aaacatggaa tcatgggtac caaaagctaa agaaagttgg
      601 aagaaagctg ggcctaatgt agtagaagga acaaaagaca tgattttatt gccaggtagt
      661 gaagaagaag atcatgatca cggagaagaa gatcaccatc atgaactaga tcctcatacg
      721 tgggtttcac ccaaaatggc aattaaggaa gtttcaaata tcaaggatca gttagttaaa
      781 ttgtatccga aaaaagcaaa agtatttgag acaaatgctg aaaagtattt gactaaactg
      841 aaacggttgg atgctgacta taccactagt cttaaagaag cgaaacaaaa aagttttgtg
      901 acgcaacacg cagcctttgg atat
//
LOCUS       DAXLPC010000227          895 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.237, whole genome shotgun sequence.
ACCESSION   DAXLPC010000227 DAXLPC010000000
VERSION     DAXLPC010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.237"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            3..581
                     /locus_tag="ACF3UE_002856"
     CDS             3..581
                     /locus_tag="ACF3UE_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFD3636168.1"
                     /translation="MDNKTNNTKTEIKKNDISKASEAIKGELVFEDKVIQKIIGIALD
                     EIDGLLTVDGGFFSNIAGKLVNTDNTTSGVDVEVGKKQVAVDLSIVAEYGKDVTTIYD
                     KIKQVISNEVRKMTGLDVIEINVNVVDVKTKEQYEKDSVTLQDHLTDAASATGEFASK
                     QIEKSKEALGVASEKVNDGVQNVKEATEPRVK"
BASE COUNT          359 a          100 c          153 g          283 t
ORIGIN      
        1 taatggataa taaaacaaac aatacaaaaa cagaaattaa aaagaatgat atatcaaaag
       61 cttctgaagc tattaaagga gaattggttt ttgaagataa agtaattcaa aaaataatcg
      121 gtattgcatt agatgaaatt gatgggcttt tgacagttga tggaggattc ttttcaaata
      181 tagccggaaa attagtaaat acagataaca caacttctgg agtcgatgtt gaagtaggta
      241 aaaaacaagt tgcagtagat ctttcaatag tggctgaata tggtaaagat gtaactacaa
      301 tttatgataa aattaagcaa gtaatctcaa atgaagttag gaaaatgact ggcttagatg
      361 taattgaaat taacgtaaac gtcgtagatg taaaaacaaa agaacaatac gaaaaagatt
      421 cagttaccct acaagatcat cttactgatg cagcttctgc tactggagaa tttgcttcaa
      481 aacaaattga gaaatcaaaa gaagctttag gagtagcaag tgaaaaagtt aatgatggtg
      541 tacaaaacgt aaaagaagca acagaacctc gtgtaaaata gtaacttcct ttctgtaata
      601 tacaacatat aaaattgaaa gactaaattt aaggctctta gatattttaa tgtagatata
      661 gaagaaagaa ctgaaatata ataaaaccag ttaggtatag gacttaactg gttttagttt
      721 ctttaagtgg gagatcaaca tctgaataag cattttgtga aagatgtaga aatctttata
      781 gctgttggtt actcattttg tatttcttat ttagttcttt tgtctctttc tagtaaatct
      841 ttacaatatt ttagttctca atttatatta tttaaaaatt ttattatcgt ataaa
//
LOCUS       DAXLPC010000228          832 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.238, whole genome shotgun sequence.
ACCESSION   DAXLPC010000228 DAXLPC010000000
VERSION     DAXLPC010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.238"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            143..400
                     /locus_tag="ACF3UE_002857"
     CDS             143..400
                     /locus_tag="ACF3UE_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636169.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(632..>832)
                     /locus_tag="ACF3UE_002858"
     CDS             complement(632..>832)
                     /locus_tag="ACF3UE_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HFD3636170.1"
                     /translation="GMSAFNYQDKVQTSTELLMKIEKEKLLYITKTSPYNKTDEENFH
                     LIVTTLQTELNDIISDFNQVNN"
BASE COUNT          321 a          102 c          110 g          299 t
ORIGIN      
        1 ttttctgtcc acgttcattt tactccaaag ttttcctcat ttcaaaagaa aatcacagaa
       61 tacacgaaga agcgtttcta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt attactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tttgtctaca gtctgaataa
      481 attttaaatt tattgtccat aatgttatta tgaatttata gcattaagaa aagagataag
      541 actttacatt tttttaggaa tgtaaagtct tatctctttt cttaattgta caattagtat
      601 tatctgcact actttctaat taaataaatt tttagttatt aacttgatta aaatcagaga
      661 taatatcatt taattcagtt tgaagggttg taacgattaa atggaaattt tcttcatctg
      721 ttttattata tggggatgtt ttcgttatat ataacaactt ttctttttca attttcatta
      781 ataactctgt cgaagtctgt actttatctt gataattaaa tgcagacata cc
//
LOCUS       DAXLPC010000229          811 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.239, whole genome shotgun sequence.
ACCESSION   DAXLPC010000229 DAXLPC010000000
VERSION     DAXLPC010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.239"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            387..785
                     /gene="spxA"
                     /locus_tag="ACF3UE_002859"
     CDS             387..785
                     /gene="spxA"
                     /locus_tag="ACF3UE_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFD3636171.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT          309 a          110 c          143 g          249 t
ORIGIN      
        1 acagagaaaa taagcgttat aataaagaac agtattattt aaaatgacag aaaacattac
       61 tattaaagaa ataaaaaaca taaaaaatct taagaaatcg gtttcattta gcttttgaga
      121 taaaataata gtacagtttt atacgctgtt tcatatgttt agaaaatttg aattagattt
      181 gaaaactcta atttttaaat gataaaaaaa gcgagaatgc tggttttact gtatattaac
      241 cttagataac tttcattttt ttaaaaaaat tatgaaaaaa aggtagctat ttaaaagttg
      301 attatgtata atagaaacag atgggagatt attatgatct tctgttacaa aaaagtgatt
      361 cttatcacga aaaggagtgg tgcacgttgt taacattata tacttcccca agttgtactt
      421 cctgcagaaa ggctcgtgcg tggttgcaag aacatcagat tccatttgtt gaacgtaata
      481 ttttttcaga accattgaac agttctgaat taaaagcgat tttacaaatg acagaagacg
      541 gaacagaaga aatcatctcg acacgttcca aagtattcca aaaactgaac atggatttag
      601 atgatctgcc gttacaagaa ttattggaac ttgtgcaaaa caatcctgga ttgcttcgcc
      661 gtccaatcat gattgatgat aaacgtctgc aagttggttt taatgaagat gaaattcgtc
      721 ggttcctacc gcgcgatgta cgacaattag aattacgtca agcacaattg atggctggat
      781 tatagaagga taatacgaaa cttggaaaag a
//
LOCUS       DAXLPC010000230          802 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.240, whole genome shotgun sequence.
ACCESSION   DAXLPC010000230 DAXLPC010000000
VERSION     DAXLPC010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.240"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..793
                     /locus_tag="ACF3UE_002860"
     CDS             <1..793
                     /locus_tag="ACF3UE_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFD3636172.1"
                     /translation="CMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGIADPQPI
                     IQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRKQNLNLS
                     ALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENHYNGKHY
                     HQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQDFIVAM
                     QGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
BASE COUNT          306 a          134 c          127 g          235 t
ORIGIN      
        1 atgtatgtgt tgcagtcttc gcagtgattt attagcaata ttgatttctt tactggaaac
       61 aatagaagaa catcaacaac caatttcaca aatcatcatt gaaactacag gtatagcaga
      121 tccccaacca atcattcaaa cacttttaac agcgcctcaa ctaagaggaa gagtatatat
      181 cgatagttta ttgactgtta ttgatagtga cagttttgaa cttattgaaa gagaaccaca
      241 agcccttaag caacttgtca tggcagatcg catttttgtg tctagaaaac aaaacttgaa
      301 tttatctgca ctaaaaaaat tacagagaga aatcaaaagt attaaccctt tatccgatat
      361 tcgaatgttc acacatagtg aaacgattca aaaaaaggat ttttataatt tgaaaaaatt
      421 taatcatccc ttagtttttg aaagtgattc atcagaaaat cactataatg gcaaacacta
      481 tcatcaacac catcaagtac atgagtttaa atcaattctc ttaacttcag atcaagacat
      541 aaaaaaagat tttttactcc aatggattga ctggttgatt ttaaccaacc aagggagcct
      601 gtatcgtttt aaaggattga ttgctttaca agagcaggat tttatagttg ccatgcaagg
      661 ggtaaacgaa caggttaatt ttcaatacac cactcgacaa aaagaccaaa ccactattat
      721 tctaatcgga aaaatgttgg atgaagaaag gatcaaacag agttttgata aattactggc
      781 ggaaagcaaa taatgataag ta
//
LOCUS       DAXLPC010000231          798 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.241, whole genome shotgun sequence.
ACCESSION   DAXLPC010000231 DAXLPC010000000
VERSION     DAXLPC010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.241"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..380
                     /locus_tag="ACF3UE_002861"
     CDS             <1..380
                     /locus_tag="ACF3UE_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HFD3636173.1"
                     /translation="EYKDYYTTGYKTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKI
                     LNYEKGNRGVRFNFETDDAGAGRFKYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEM
                     HNWPTFYPASLSEHEIAQEMMAH"
     gene            404..643
                     /locus_tag="ACF3UE_002862"
     CDS             404..643
                     /locus_tag="ACF3UE_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3636174.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSV
                     DTVRRVLKQDRDCCFIKVNTGRSRRLAKRYNSLIN"
BASE COUNT          282 a          100 c          143 g          273 t
ORIGIN      
        1 ccgagtacaa agattattat actactggct ataagacaga tattgatact atcaacatta
       61 aagacaacac cattgatttt gtagtcaacg gtgaacatca tcaatacaca tacaaatatg
      121 ttggatacaa aattttgaat tatgaaaaag gaaaccgtgg tgttcgtttt aattttgaaa
      181 ctgatgatgc aggtgctggt cgttttaaat atattcaatt tagtgatcat ggaattgcac
      241 caagtaaggc agagcatttc catattttct ttggtggaga aagtcaagaa aaactttata
      301 atgaaatgca taattggcct actttctatc cagcttcatt atctgagcat gagattgctc
      361 aagaaatgat ggcccattaa aatccaatct ttggagaaaa tacatggtaa gaaaagtatt
      421 attgtctatg gattccaaga atattgatgc ttatcggcgt tatcgatttg caaagcaaat
      481 gagattaaat gggagtacat tagctgatat tgctgcaact ttacatgtta gtgttgatac
      541 agttcgtaga gtgttaaaac aagaccggga ttgttgtttt atcaaggtca atactggaag
      601 aagtagacgt ttagcaaaac gatataatag tttgattaat tagttgtaac agtagagcag
      661 attaattttc ttttattagg atttgatctg ctctttatta tgtataggaa ttaacatatt
      721 cgaaaaaata ttacaaaatt gtaatgctat tatttataat taattatttt acaatgctaa
      781 aattgatgat aatatttt
//
LOCUS       DAXLPC010000232          779 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.244, whole genome shotgun sequence.
ACCESSION   DAXLPC010000232 DAXLPC010000000
VERSION     DAXLPC010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.244"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(209..400)
                     /locus_tag="ACF3UE_002863"
     CDS             complement(209..400)
                     /locus_tag="ACF3UE_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636175.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
BASE COUNT          288 a          125 c           97 g          269 t
ORIGIN      
        1 taattcgctt gtggcgaaac ccgacctgga gtttgtctct gtattttgaa ccctaaaaat
       61 taatcaaaca gactgatatt ctcataatca gcgcgaaata agccattaag tacagttttc
      121 ctacctattt ttgataaccc gctggttagt taatattcct tttccgagag agataaatga
      181 ttggttaaat ctatatacat ctcaaccttt aaaaatgttt tcgaaatact tcatcagtac
      241 atgtcataca aattaccagt gcattctcaa attctagttc tttaattgat ttcagttgag
      301 gagcagttac ttttggcgga aatttccatt tttgtccaaa cctcttcccc cgatgaaatt
      361 tctttgttgc aattattgca atgaaaaatt tttgtttcaa aaatatacat aattacttcc
      421 tccaataaaa actatctacc tctcaaatta tttttctcta ataagaaaaa cagaaaaggt
      481 aataagatac aacagtgatg attcctaata aagaaaagac tacaataata tttttctaac
      541 ttatcgcctt caaagaaata gtttcttatt tttcactaaa ataaaaaatt tattgcaaaa
      601 aaaatagaag tgacaaaatt atcaatcatt tcaaggtaat ataactacct gagtttatta
      661 tcgattaaaa tgctaactac atttgcaaga gaagcgagag ttaaaggtaa atatagaatt
      721 tctacttttt tagcaataga aataggaata aaatatttaa aatgtataga aactttctt
//
LOCUS       DAXLPC010000233          777 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.245, whole genome shotgun sequence.
ACCESSION   DAXLPC010000233 DAXLPC010000000
VERSION     DAXLPC010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..777
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.245"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            32..>777
                     /locus_tag="ACF3UE_002864"
     CDS             32..>777
                     /locus_tag="ACF3UE_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636176.1"
                     /translation="MKFAIRKKKGGGAASFIIGCLIFGNIFLNGAIANASSIENSYAI
                     SGFGNQTKGGYFLYNKGIKTESVIDNQVAFCFDKNVIAKLNDRGFSNPGYQLYNEKDE
                     QLLKVYSNEKINKVRNIMAYAWDNFITKYPYLNTYTAASNDDRASLARGISHAIWVTL
                     GQTTEKKSRSDLGGVNTNAYKFYKEALNYKPLAKDINNYDISLLIPTDDNNILQVNAS
                     QSLITVKKIDPDKPVNPDPETPVTPETPDP"
BASE COUNT          288 a          109 c          140 g          240 t
ORIGIN      
        1 gggaatgttt actagttgta aagaaaaaag attgaaattt gcaattagaa agaagaaagg
       61 tggtggtgct gcgtccttta taattggctg tttaattttt ggaaacatat ttctcaatgg
      121 cgctattgct aatgcgtcta gtatagaaaa tagttatgca ataagtggtt ttggtaatca
      181 gacaaaaggt gggtatttct tatataataa gggtattaaa actgaaagtg ttattgataa
      241 ccaagtagct ttttgttttg acaaaaacgt tatagctaaa ctgaatgatc gtgggttttc
      301 aaaccctggt tatcaattat acaatgaaaa agacgaacaa ctcttgaaag tatatagtaa
      361 tgaaaaaatt aataaagtaa gaaatatcat ggcttacgct tgggataatt ttattactaa
      421 atatccctat ttaaatactt atacagccgc ttctaatgat gatcgtgctt ctcttgccag
      481 aggaattagt catgctattt gggtaacctt gggacaaaca acagagaaaa aatcaagaag
      541 tgatttaggt ggcgtaaata ctaatgctta taaattttat aaagaagctc taaattacaa
      601 gccacttgca aaagatatta acaattatga tattagttta cttattccaa ctgacgacaa
      661 taatattttg caggtaaatg cttctcaatc attaataacg gttaaaaaaa tcgatccaga
      721 taaaccagta aatccagatc cagaaactcc ggtaacgcca gagactccag atccaga
//
LOCUS       DAXLPC010000234          748 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.247, whole genome shotgun sequence.
ACCESSION   DAXLPC010000234 DAXLPC010000000
VERSION     DAXLPC010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.247"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            391..474
                     /locus_tag="ACF3UE_002865"
                     /pseudo
     CDS             391..474
                     /locus_tag="ACF3UE_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502600.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MLS leader peptide"
     gene            523..606
                     /locus_tag="ACF3UE_002866"
     CDS             523..606
                     /locus_tag="ACF3UE_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HFD3636177.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
BASE COUNT          257 a           99 c          131 g          261 t
ORIGIN      
        1 aaaaagcttt aactacaagc tttttagaca tctaatcttt tctgaagtac atccgcaact
       61 gtccatactc tgatgtttta tatcttttct aaaagttcgc tagatagggg tcccgagcgc
      121 ctacgaggaa tttgtatcga taagaaatag atttaaaaat ttcgctgtta ttttgtacat
      181 ttaacttgac ggtgacatct ctctattgtg agttattagt ggtacagttt tcaaccgttt
      241 taattataaa aaagtggtgc atttttaaat tggcacaaac aggtaacggt tattgcaggt
      301 gtatttctta tctatgggtt taacatggat tttatcatta aaatcatgag tattgtccga
      361 gagtgattgg tcttgcgtat ggttaaccct aaagttatgg aaataagact tagaagcaaa
      421 cttaagagtg tgttgatagt gcattatctt aaaattttgt ataataggaa ttgaagttaa
      481 attagatgct aaaaatttgt aattaagaag gagggattcg tcatgttggt attccaaatg
      541 cgttatgtag ataaaacatc tactgttttg aaacagacta aaaacagtga ttacgcagat
      601 aaataaatac gttagattaa ttcctaccag tgactaatct tatgactttt taaacagata
      661 actaaaatta caaacaaatc gtttaacttc tgtatttgtt tatagatgta atcacttcag
      721 gagtgataac atgaacaaaa atataaaa
//
LOCUS       DAXLPC010000235          736 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.248, whole genome shotgun sequence.
ACCESSION   DAXLPC010000235 DAXLPC010000000
VERSION     DAXLPC010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..736
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.248"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..734
                     /locus_tag="ACF3UE_002867"
     CDS             <1..734
                     /locus_tag="ACF3UE_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFD3636178.1"
                     /translation="DKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRK
                     LMSQMGLTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKI
                     YLSPILDLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQ
                     YQKKLKENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIR
                     WYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          318 a           94 c          122 g          202 t
ORIGIN      
        1 cagataaata tagcaagata aagcaagaaa ttacagcgat tgtaaaagaa tcaagaaact
       61 cttatggtta tcgtagagtc actttagcgt taaagatgaa aggatataca atcaatcata
      121 aaacagttag aaaattaatg tcccaaatgg gacttacctg tcaaatccga ataaagcgat
      181 ataaatctta taaaggaaca gtaggaaaaa ttgccaagaa tgtgttaaaa cgaaattttt
      241 cagtagatac acccaataaa aaatgggtga cagacgtcac tgaattcaag ataaaaggaa
      301 gaaaaatcta tctatctcct atacttgatt tatttaacgg agaaataatt agttatagta
      361 tatcaactag tccaacatat aaactgattg aagaaatgct tcaacaagca attaaaaaaa
      421 agggaactga gggttcactg attctacatt cagatcaagg atggcagtat cagatgccac
      481 aatatcaaaa aaaattaaaa gagaataaca ttattcaaag catgtctaga aaaggaaatt
      541 gcttagataa ttctgtaata gaaaattttt ttggtgtgct taaatcagag tttttttatc
      601 gagaaaaatt ccgatcaatt gagatatttc aaagtaaatt aaatgagtat attaggtggt
      661 ataataacaa aaggataaaa ctaaagttaa atggactatc tccagtagaa tatcggaaac
      721 agtccattaa atagtt
//
LOCUS       DAXLPC010000236          728 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.249, whole genome shotgun sequence.
ACCESSION   DAXLPC010000236 DAXLPC010000000
VERSION     DAXLPC010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.249"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..330
                     /locus_tag="ACF3UE_002868"
     CDS             <1..330
                     /locus_tag="ACF3UE_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFD3636179.1"
                     /translation="DLGGEKEKDIAVKLPGVTKNTNSKQSSDSKASFNHPSTFFNNNK
                     RSSNLNYNNSNKKRELMNQEKNKEGNRNKNTMELPKTGEKYNGLPVYVGLFTAIASII
                     GLKKNKF"
BASE COUNT          288 a          100 c          119 g          221 t
ORIGIN      
        1 gatcttggtg gagaaaaaga gaaagacata gcagtcaaat tacccggagt aacgaaaaat
       61 acaaattcta aacaaagttc ggatagtaaa gctagcttta atcatccttc tacttttttt
      121 aacaacaaca aaagatcatc taatctaaat tataataata gcaataaaaa aagggaacta
      181 atgaatcaag aaaaaaataa agaaggcaat cgaaataaaa atactatgga gttaccgaaa
      241 actggagaaa aatataatgg tcttcctgtg tatgtagggt tattcacggc gattgcaagt
      301 attatagggc tgaaaaaaaa taaattttaa tgtgggaatt attattattt ctctaattct
      361 atttgagcaa tttaaaatat gaaaatcaat aaagagaaag ttttaagttg ttaagtaaat
      421 taaatttcga ttggaagcat agttgaataa gcctaacatg ttacgaaaga taaataacct
      481 acttttcatt tctagaagag aatgtcttga tgcttataaa cagatttagc tccctatcca
      541 cttcaagtct aattcttttg tatgcaaata aagtattttt aggagagtgt tctcattaga
      601 gaacactctt tttttgtttt gaaaactact tactatacgg gtagtttcaa agtaagcgcc
      661 ccatagaaca gtaccttact aacaaatgca cctcaagata tacttgagct atcaagaagt
      721 ctggaggt
//
LOCUS       DAXLPC010000237          728 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.250, whole genome shotgun sequence.
ACCESSION   DAXLPC010000237 DAXLPC010000000
VERSION     DAXLPC010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.250"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
BASE COUNT          283 a           76 c          131 g          238 t
ORIGIN      
        1 gatttagttg tatcgtttct ttttctattt tatcgcttaa ttttaatagt taattatttg
       61 aatgatatat aaattttaat caaagaaaga caatttattg ttgaaatagt tgttgaagct
      121 ttcgaggcgt tcttgaggta cagttgaaag ctttatatcc actttagagg tatacaaaag
      181 tttaatatga gaattctcag aagataatct actataaaac agtagataag tcagcgccca
      241 aaactaacca ttcgttgtaa aagcaccgtc gtcgatgatc gcttagattg gctatacgaa
      301 agtgagcaac aaaaaaagtt tgggaataaa aagaaagcgt actgtaatct tccaaaaggt
      361 taagatgatt ttgataaaaa aatttaatat atttgttatt tttataatgt gatgatataa
      421 aatggatcga acagttgaat gaggtgttta tatgaaaaaa agtcactcct tatcgtccaa
      481 aacctaaaaa cgtttttgaa agaggaagca taaatatttt gaaggagaaa aggggcaaga
      541 gttaaaagag aagaatcaaa aaagaagtcc aagaaagaaa aaatgtgagt atatttttta
      601 gaaagaaagg aattgttgcg aaactagacc gtaaagattt ataagtaatc agtaacccat
      661 actttttata tttaaagagg ttatttttct gtaaatcgtt gtaaaaaata tctgagttgt
      721 agtatttt
//
LOCUS       DAXLPC010000238          712 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.251, whole genome shotgun sequence.
ACCESSION   DAXLPC010000238 DAXLPC010000000
VERSION     DAXLPC010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..712
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.251"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            45..656
                     /locus_tag="ACF3UE_002869"
     CDS             45..656
                     /locus_tag="ACF3UE_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFD3636180.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFRKIGVEKVFAEKKSGRNTVERP
                     EFNKMLSFVREGDTLVFESLERLGRNSDEILETVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVINIFSWTAQNEREEIKRKQKQGIAIAKKKGVYKGKPYEYSSTAKNPQ
                     KRFIYNEIVRMLGEGVPIKRIAEKTGTNRNLVYRIKKRISESD"
BASE COUNT          280 a           80 c          150 g          202 t
ORIGIN      
        1 cctagttaat taaactagag taaaattatt tgtaggtgtt aaatatgtta gttggctatg
       61 cacgagtcag ttcagatgat caaaatttgg aaagacagct tgaagaattt agaaaaattg
      121 gtgtcgaaaa agtatttgct gagaaaaaat ctggacgtaa cacagtagaa cggccagagt
      181 tcaataaaat gttgtcattt gtcagagaag gggatacgct tgtttttgag tcgcttgaac
      241 gcttaggaag aaattctgat gaaatactag aaacagtatc ttttatagat aaaaatggta
      301 tgggcttaat ggttttgaat ttaccaattt tagatacaaa atttggtgat ccaaacttag
      361 aaaaacttgt tagaagctta gtaattaaca ttttttcttg gacggctcaa aatgagaggg
      421 aggaaattaa gagaaaacaa aaacaaggaa tagcaattgc gaagaagaaa ggagtctata
      481 aaggaaaacc ctacgaatat tcttctactg caaagaatcc acaaaagagg tttatctata
      541 atgaaatagt aagaatgctt ggagaaggtg ttccgattaa gcgaattgca gaaaaaacag
      601 gaacaaatag aaatttagtc tatagaataa agaaaagaat aagtgaatct gattgatttt
      661 aagttctttg agaaatcaat gttacgagag aaggattcta agcctgtttc aa
//
LOCUS       DAXLPC010000239          705 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.252, whole genome shotgun sequence.
ACCESSION   DAXLPC010000239 DAXLPC010000000
VERSION     DAXLPC010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..705
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.252"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..89
                     /locus_tag="ACF3UE_002870"
     CDS             <1..89
                     /locus_tag="ACF3UE_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFD3636181.1"
                     /translation="AKVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(352..>705)
                     /locus_tag="ACF3UE_002871"
     CDS             complement(352..>705)
                     /locus_tag="ACF3UE_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HFD3636182.1"
                     /translation="RATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSS
                     LETPSISPKETLEKELNRKVSGKEIQPTLERIEQKMVLNKHQETPEFKAIQQKLESLQ
                     PPTPPIPKTPKLPGI"
BASE COUNT          200 a          106 c          127 g          272 t
ORIGIN      
        1 acgccaaagt aaacaattta agtaccgtta cttatgagca agtattgtct atttttaata
       61 gttatctatt atttaacggg aggaaataat tctatgagtc gcttttgtaa atttggaaag
      121 ttacacgtta ctaaagggaa tgtagataaa ttattaggta tagggcacct ctaataacta
      181 ccaattaatt cacctcaaaa tgaaattaga aaaaaacagc gaaattttta aatctatttc
      241 ttatcgatac aaattcctcg taggcgctcg ggaccccaac atgaggaaat gtttttataa
      301 aaaaagagta gttaccgttt tttggtaact actcttttcc ttttttaagg tttaaatacc
      361 tggaagttta ggtgttttgg gtattggtgg tgtaggtggc tgcaagcttt ccaatttttg
      421 ttgaattgct ttaaattcag gtgtctcttg gtgtttattt agaaccattt tttgctctat
      481 tcgttctaaa gtcggttgaa tttctttccc tgatacttta cgattcaatt ctttttctaa
      541 ggtttctttt ggactaatag aaggtgtttc caaacttgaa tagagtttta ctccttctct
      601 gttatatagc cttatatcgc taaataagcc cgttttatga agggtttcta aattggtcgg
      661 taagtttttg acaacaatat catgcgcttg ttttggtgtt gccct
//
LOCUS       DAXLPC010000240          696 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.253, whole genome shotgun sequence.
ACCESSION   DAXLPC010000240 DAXLPC010000000
VERSION     DAXLPC010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.253"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(53..628)
                     /locus_tag="ACF3UE_002872"
     CDS             complement(53..628)
                     /locus_tag="ACF3UE_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HFD3636183.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          125 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaacg
//
LOCUS       DAXLPC010000241          690 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.254, whole genome shotgun sequence.
ACCESSION   DAXLPC010000241 DAXLPC010000000
VERSION     DAXLPC010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..690
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.254"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            178..414
                     /locus_tag="ACF3UE_002873"
     CDS             178..414
                     /locus_tag="ACF3UE_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HFD3636184.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            433..648
                     /locus_tag="ACF3UE_002874"
     CDS             433..648
                     /locus_tag="ACF3UE_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HFD3636185.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
BASE COUNT          225 a           95 c          170 g          200 t
ORIGIN      
        1 taattccaca aaaactttga aaacagttct tgaacactaa ctttttcatt cctgaatcaa
       61 atttattttg gaaattttac tattcaagaa taaacttgat aagtttcagg aagattttta
      121 ctgttaatca aatacgtatg ttacagtagc accgtaaaaa atattattta aagaagcgtg
      181 tttaaacatg caaaatgtaa aggaactaag tattgtggaa atgcacaaac tgttggtgga
      241 ggcaataatg cttggggaaa attggggcaa gttgtaggtg gacttaccac aggggcagta
      301 ggtggtgcag gtttaggaac agcaatttgc ggaccagctt gcggtgttgt tggagggtta
      361 tatggagctg tcgctggagg tgctgcagct ggctgggatg ctcgaaaaaa ataaaaaagg
      421 agaataagta gtatgcatat taaaaacaca aaaacaacat ttatattatc ttcagaagag
      481 ttgaaaaata ttcaaggtgg gagtgccgtg ggagttttag gcactacttt ttctggggca
      541 acagcaggag taaaactttg ttcagccgga ggaccttatg caatagctgc ttgtggtgta
      601 ggtggagctt tattaggtgc tggattcagc atgtggaccg gtgcgtaaac aattaaaaaa
      661 tatcaaacct caagattggt ttgtgtcgat
//
LOCUS       DAXLPC010000242          677 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.255, whole genome shotgun sequence.
ACCESSION   DAXLPC010000242 DAXLPC010000000
VERSION     DAXLPC010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.255"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            73..234
                     /locus_tag="ACF3UE_002875"
     CDS             73..234
                     /locus_tag="ACF3UE_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFD3636186.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            253..>677
                     /locus_tag="ACF3UE_002876"
     CDS             253..>677
                     /locus_tag="ACF3UE_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFD3636187.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEG"
BASE COUNT          281 a           63 c          117 g          216 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaaagatat tgaaaaatta
      481 aaagaaattg aagaaaaaat aattcaatat gatggattag caaaactaaa agatgctaaa
      541 gtagttagcg gagaacaaag aataaataga gaagatttat ctgacgaatt taagaatgtt
      601 gtttcactcg aagctacaaa taatactaaa agaaatattt tatttagtag tggagtattt
      661 acaattaaag aaggtaa
//
LOCUS       DAXLPC010000243          666 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.256, whole genome shotgun sequence.
ACCESSION   DAXLPC010000243 DAXLPC010000000
VERSION     DAXLPC010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.256"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>666
                     /locus_tag="ACF3UE_002877"
     CDS             <1..>666
                     /locus_tag="ACF3UE_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
                     /protein_id="HFD3636188.1"
                     /translation="MYGYHYTPQTMSKMTKVLTEEVNAFKVRTLNDKYVAIFMDATYI
                     PLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDIYSRGVHDVLLF
                     ITDGLKGMKDTIHQIYPKAKYQHCCVHVSRNIAHKVRVKDRKEICDDFKAVYQASSKE
                     EANTFLGSMIEKWQKTYPKVTQSLIKNQDLLTFYEFPPGIRRSIYSTNLIESFNKQIK
                     KYS"
BASE COUNT          227 a          123 c          125 g          191 t
ORIGIN      
        1 aaatgtatgg gtatcactac acgccccaaa ccatgtccaa aatgactaaa gtgctgactg
       61 aagaagtaaa tgcatttaaa gttagaactc taaatgataa gtatgtcgct attttcatgg
      121 atgctactta tattccttta aaacggcaaa ccgtctccaa agaagcaatc tatattgcca
      181 ttggtatacg agaagacggc actaaagaag tactaagtta tgcgattgct ccgactgaat
      241 cgacctacgt ttggaatgag ttgttacagg acatttactc cagaggggtt catgatgtct
      301 tactgtttat caccgatggc ttaaaaggca tgaaagatac gattcaccag atttatccta
      361 aagctaaata ccaacattgc tgtgttcacg tttcccgtaa tattgctcat aaagtacgtg
      421 tcaaagatcg aaaagaaatc tgtgatgatt ttaaggctgt ttatcaagct agctcaaagg
      481 aagaggcaaa taccttttta gggagtatga ttgagaagtg gcagaaaact tatcctaaag
      541 tgacgcagtc actgataaaa aatcaagatt tattgacttt ttatgagttt ccgcctggta
      601 tccgccgaag catttactca actaatttaa tcgaatcttt caataaacaa atcaagaaat
      661 acagcc
//
LOCUS       DAXLPC010000244          642 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.257, whole genome shotgun sequence.
ACCESSION   DAXLPC010000244 DAXLPC010000000
VERSION     DAXLPC010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.257"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            191..432
                     /locus_tag="ACF3UE_002878"
                     /pseudo
     CDS             191..432
                     /locus_tag="ACF3UE_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            481..564
                     /locus_tag="ACF3UE_002879"
     CDS             481..564
                     /locus_tag="ACF3UE_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFD3636189.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
BASE COUNT          266 a           77 c          118 g          181 t
ORIGIN      
        1 gccgttgtaa aaattgggga aaagggatat attgatttta tatctttctc aaaataaaca
       61 taaaagccct ttaaagaggg cttttatata ttaatcacaa atcacttatc acaaatcact
      121 tatcacaaat cacaagtgat ttgtgattgt tgatgataaa ataagaataa gaagaaatag
      181 aaagaagtga gtgattgtgg gaaatttagg cgcacaaaaa gaaaaacgaa atgatacacc
      241 aatcagtgca aaaaaagata taatgggaga taagacggtt cgtgttcgtg ctgacttgca
      301 ccatatcata aaaatcgaaa cagcaaagaa tggcggaaac gtaaaagaag ttatggaaat
      361 aagacttaga agcaaactta agagtgtgtt gatagtgcag tatcttaaaa ttttgtgtat
      421 aataggaatt gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc
      481 atgttggtat tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa
      541 aacagtgatt acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta
      601 tgacttttta aacagataac taaaattaca aacaaatcgt tt
//
LOCUS       DAXLPC010000245          640 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.258, whole genome shotgun sequence.
ACCESSION   DAXLPC010000245 DAXLPC010000000
VERSION     DAXLPC010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.258"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..283
                     /locus_tag="ACF3UE_002880"
     CDS             <1..283
                     /locus_tag="ACF3UE_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFD3636190.1"
                     /translation="LIQDDLHHTHRLWLMNKINLYFGHSYVFAFYDYRTNITEVDLVI
                     SNYYIDTGKTPLLLMKNIPTERNWRLFEKTIYQLKKEKEVVKSAFCPEY"
BASE COUNT          218 a           89 c          119 g          214 t
ORIGIN      
        1 tttaatacaa gatgatttac accatacgca tcggttatgg ttaatgaata aaattaatct
       61 gtattttggg cattcttatg tttttgcttt ttatgattac aggacaaata taactgaagt
      121 agatttggtt atttctaatt actacatcga cactggaaaa acgccattac tgttaatgaa
      181 aaatatacct accgaaagaa actggcgttt gttcgagaaa acgatttatc aattgaaaaa
      241 agaaaaagag gttgtgaaat cagcgttttg tcctgagtat tagagaaaca aacggaaaaa
      301 tagtttttca tattttgccg tttttgagct aataccgagg gacagctgat tgaacaccat
      361 ttattgagag attgtgaaaa aactgtcctg catcaagtaa taagaacagc caagtaaaaa
      421 cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttggca agagaacacc
      481 gtttattcgg aaaaagggac tgtgacacta catgtcacag tccctttttg attgaattat
      541 ctcatttgtt ttctaatttt ttctttattt gagaaaatag ttgaactgga taaaaagtac
      601 tggacgtgtc aaaattattt tggatcaaat tagatctatt
//
LOCUS       DAXLPC010000246          625 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.259, whole genome shotgun sequence.
ACCESSION   DAXLPC010000246 DAXLPC010000000
VERSION     DAXLPC010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.259"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            18..>625
                     /locus_tag="ACF3UE_002881"
     CDS             18..>625
                     /locus_tag="ACF3UE_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HFD3636191.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRK"
BASE COUNT          202 a          110 c          128 g          185 t
ORIGIN      
        1 agaggacgat atgctatatg aatgattcta tcaaaaaaat gctgcgatta atagagaaag
       61 atttgatgat tacagaggtc tcttacgaga cctttcagaa gaaaaagacg ttgatcgtcg
      121 atgctgtttt ctcacctgct ccccatacct gtagaaattg tggttctact gtggtagatg
      181 gaaacgggaa agtaattgta gtgaaaaatg ggaagaagga aacgattgtc cgctttgaac
      241 aatacaatca catgcctttg gttatgcgct taaaaaagca gcgctatacc tgtaaaaact
      301 gtcgaaccca ttggacggct caaagttatt ttgttcaacc cagacattca atcgcgaatc
      361 atgtcagata taaaattgct tctttactga ctgaaaaagt atctttatct tttattgcga
      421 aaaattgtca ggtatctttg accaccgtta ttcgtacgtt gaaagagttt aaaagctact
      481 taccaaagca atctaagagg attctcccca gagtattgat ggttgatgaa tttcgttcgc
      541 acgcttccat agaagataaa atgagcttta tttgcgcaga tggcgaaaca ggacaattaa
      601 ttgatgtctt gcctacgcgt aaatt
//
LOCUS       DAXLPC010000247          617 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.260, whole genome shotgun sequence.
ACCESSION   DAXLPC010000247 DAXLPC010000000
VERSION     DAXLPC010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.260"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            28..>617
                     /locus_tag="ACF3UE_002882"
     CDS             28..>617
                     /locus_tag="ACF3UE_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3636192.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGR"
BASE COUNT          212 a          113 c          119 g          173 t
ORIGIN      
        1 ccaaagaatt ataaggagtg agtacaaatg acctataccc atcttacaac ggatgaactt
       61 gtaataatag agtcttattt caaaatgaat caatctgttg ctaaaactgc ccattgcttg
      121 aatcgttcaa gacaaacgat ccataaagta tatctgttct tcaagcaagg aaaatcagcc
      181 ttagaatatt atcaacagta taagaaaaac aaatcaaact gtggtagacg tccgcttgtt
      241 ttacccgagg aacaatcaga atatattcaa agaaaggttg ttcaaggatg gacacccgat
      301 gtgattgttg gtcgtgcagc gtttcctatt agttgttctg ctcgtaccat ttatcgtatg
      361 ttcaaaaagg ggctatttga ttcttctgac ttaccgatga aaggcaagcg taaaccgaat
      421 ggacatcaag aaagacgtgg aaaacaaact ttccgccgct ctattcatga acgtgaaaag
      481 gattatagcc aattctcaaa tgagtttggt caccttgaag gtgacactat cgtaggtctg
      541 aaacataaaa gtgctgtaat taccttagtt gaacgattat caaaagttat catcacattg
      601 aaaccgtgtg gtagaca
//
LOCUS       DAXLPC010000248          604 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.261, whole genome shotgun sequence.
ACCESSION   DAXLPC010000248 DAXLPC010000000
VERSION     DAXLPC010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.261"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            51..>604
                     /locus_tag="ACF3UE_002883"
     CDS             51..>604
                     /locus_tag="ACF3UE_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HFD3636193.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRT"
BASE COUNT          221 a           97 c          119 g          167 t
ORIGIN      
        1 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
       61 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
      121 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
      181 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
      241 agaaaaataa aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag
      301 gaaaatggca ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt
      361 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
      421 ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga
      481 aactaaaaga atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata
      541 atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac
      601 gcac
//
LOCUS       DAXLPC010000249          594 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.262, whole genome shotgun sequence.
ACCESSION   DAXLPC010000249 DAXLPC010000000
VERSION     DAXLPC010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.262"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            431..577
                     /locus_tag="ACF3UE_002884"
                     /pseudo
     CDS             431..577
                     /locus_tag="ACF3UE_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
BASE COUNT          197 a           85 c           97 g          215 t
ORIGIN      
        1 tacgattatt gaaaaaaaaa gataaaactt gattaattga agtattgctt aaatttggaa
       61 gctatgaggg aagaataaaa gagttaggac gggattatct actatttttc tttgttttaa
      121 atatttgtta tctttgaaca taaaagagaa atgtgtcgac tgcagtgttg tgtccctcat
      181 cacgaataaa cggtgttcaa ttagctgatc ttgtattaac ttaaaaaatg gtaaagtacg
      241 agttgctatt ccccattttc aattttctaa cgctcaggac aaaatactgt tttcacaacc
      301 tcattggaat aaaagcatat atattgtttc aagaacgaaa tcttgttatc tttttaaagg
      361 gcatctgtcc aaaatctaat tttaggaggt acgttttggt atttattcgt acaaataaaa
      421 gagaattatc tttattcatg taacgcatcc aattgatttt ttcatgtacg ctcctggaac
      481 gattttactg acgattgctt atttaactgc gaatcgctca ttagctttta tcatagctat
      541 ccatattttg aataacgttc ttggctttgt attatagata cagatgacaa aaaa
//
LOCUS       DAXLPC010000250          572 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.263, whole genome shotgun sequence.
ACCESSION   DAXLPC010000250 DAXLPC010000000
VERSION     DAXLPC010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.263"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>572
                     /locus_tag="ACF3UE_002885"
     CDS             <1..>572
                     /locus_tag="ACF3UE_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3636194.1"
                     /translation="APYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLK
                     GNSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNL
                     RQGYQLYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYS
                     YSNGPLECLNNHIKVLKRNAYGFRNFYNFK"
BASE COUNT          191 a          119 c          109 g          153 t
ORIGIN      
        1 atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc
       61 gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca
      121 cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct
      181 attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg
      241 ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc
      301 ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag
      361 atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata
      421 caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca
      481 gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta aaacgcaatg
      541 cgtacggctt tcgcaacttt tacaatttca aa
//
LOCUS       DAXLPC010000251          570 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.264, whole genome shotgun sequence.
ACCESSION   DAXLPC010000251 DAXLPC010000000
VERSION     DAXLPC010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.264"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(47..132)
                     /locus_tag="ACF3UE_002886"
     tRNA            complement(47..132)
                     /locus_tag="ACF3UE_002886"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(96..98),aa:Leu,seq:taa)
     gene            complement(149..220)
                     /locus_tag="ACF3UE_002887"
     tRNA            complement(149..220)
                     /locus_tag="ACF3UE_002887"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(186..188),aa:Gly,seq:gcc)
     gene            complement(232..304)
                     /locus_tag="ACF3UE_002888"
     tRNA            complement(232..304)
                     /locus_tag="ACF3UE_002888"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(269..271),aa:Thr,seq:tgt)
     gene            complement(322..403)
                     /locus_tag="ACF3UE_002889"
     tRNA            complement(322..403)
                     /locus_tag="ACF3UE_002889"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(367..369),aa:Leu,seq:tag)
     gene            complement(411..483)
                     /locus_tag="ACF3UE_002890"
     tRNA            complement(411..483)
                     /locus_tag="ACF3UE_002890"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(448..450),aa:Lys,seq:ttt)
     gene            complement(487..559)
                     /locus_tag="ACF3UE_002891"
     tRNA            complement(487..559)
                     /locus_tag="ACF3UE_002891"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(524..526),aa:Val,seq:tac)
BASE COUNT          146 a          161 c          137 g          126 t
ORIGIN      
        1 gtagtcaaac actctatcca gttgagctat gggcgcatat ttgaaatgcc gaggaccgga
       61 atcgaaccgg tacggtgatc actcaccgca ggattttaag tcctgtgcgt ctgccagttc
      121 cgccaccccg gcgcgattgc tttggcaaag cggaaaacgg ggttcgaacc cgcgaccccc
      181 accttggcaa ggtggtgctc taccactgag ctatttccgc gtgtttaaag atgccggcta
      241 aaggacttga accctcgacc ctctgattac aaatcagatg ctctaccaac tgagctaagc
      301 cggcatgtaa aacttaaatt atgcgggtga agggacttga acccccacgc cgtaaggcgc
      361 tagatcctaa atctagtgcg tctgccaatt ccgccacacc cgcaaaaata tgagccgtac
      421 agggctcgaa cctgtgaccc tctgattaaa agtcagatgc tctaccaact gagctaacgg
      481 ctcatatgga ggttaacggg atcgaaccgc tgaccctctg cttgtaaggc agatgctctc
      541 ccagctgagc taaacctcca tggataactt
//
LOCUS       DAXLPC010000252          556 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.265, whole genome shotgun sequence.
ACCESSION   DAXLPC010000252 DAXLPC010000000
VERSION     DAXLPC010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.265"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(152..346)
                     /locus_tag="ACF3UE_002892"
     CDS             complement(152..346)
                     /locus_tag="ACF3UE_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636195.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYQSSDI
                     LTLNLTTKTFVDATEDYPFV"
BASE COUNT          171 a          113 c           88 g          184 t
ORIGIN      
        1 tgtgatagag aaataacaat ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat
       61 ttgattttga tcgggtctag tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc
      121 ttaaatttca tcttgactta tcaccattag actaaacaaa tggataatct tctgtcgcat
      181 cgacgaacgt cttcgtagtc agatttaacg ttaaaatatc gctactttga taagcttttg
      241 ccgctttgtc tgtgacgaca aaagatctgc ctgtttgaat ttctgtcaca aaaacgagat
      301 tgtctctgct tttttcaaca acaactccaa tcgttgaatg aaccatttct gcttcctccc
      361 ttctctttct tttgatataa tgtagtcgca aatcgcacca ctcaatgagt tggcggaaaa
      421 caattcattg aaaaaaagag tcctggacaa tcacgttcag gactctttta cttcttttat
      481 tcacttaaca actaacactc tgtgagtgaa atggactctt caatgtgatg ttaggatgat
      541 ttcatggaca cgattt
//
LOCUS       DAXLPC010000253          543 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.266, whole genome shotgun sequence.
ACCESSION   DAXLPC010000253 DAXLPC010000000
VERSION     DAXLPC010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..543
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.266"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            22..492
                     /locus_tag="ACF3UE_002893"
     CDS             22..492
                     /locus_tag="ACF3UE_002893"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFD3636196.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKITAAIESVL"
BASE COUNT          199 a           99 c           80 g          165 t
ORIGIN      
        1 aaatagaaag gagaaaactt tatgtctatt tataattttg aaactacttt agaagacggc
       61 actgtctatt cattgaaaaa atatgcaggc aaaccgataa tcattgttaa cactgcaaca
      121 aaatgcggtc tagcacctca atttaaacaa ttagaagaac tttaccaagc ttatcagaca
      181 caaggtctgg ttatcttagg ctttccttcc aatcaattta aacaagagct agattcagcg
      241 actgaagcag cagaagcttg taaaaccact tatggcgtta ccttccctat gcatcaattg
      301 attgacgtaa atggagaaaa tacagatcct ctttttactt atcttaaaaa tgaagctcct
      361 ggtactgtca ctaaagcaat aaaatggaat tttactaaat ttttgattga tagaaatggc
      421 aaagtaatcg aacgatttgc accacaaact tctccattga aaataaccgc tgcaattgaa
      481 tccgttcttt aacttaataa aaataaaaaa agatgaacta tttctagttc atctttttgc
      541 ctt
//
LOCUS       DAXLPC010000254          534 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.267, whole genome shotgun sequence.
ACCESSION   DAXLPC010000254 DAXLPC010000000
VERSION     DAXLPC010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.267"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>534
                     /locus_tag="ACF3UE_002894"
     CDS             <1..>534
                     /locus_tag="ACF3UE_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFD3636197.1"
                     /translation="YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNK
                     LSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKV
                     DKWFPSSQICSECGHKDG"
BASE COUNT          208 a           71 c           96 g          159 t
ORIGIN      
        1 tatatttctt tgttgtgtaa agaagaaatt atcgaattac ctaaaactaa ttccacaatt
       61 ggtattgact taggtattat ggactttgcg attctttctg atggacaaaa aattgataat
      121 aataaattca cgtccaaaat ggaaaagaaa ctaaagcgtg aacaacgcaa attgtctagg
      181 cgtgctttat tggctaaaaa taaaggtacc aatctatttg aagctaaaaa ttatcaaaaa
      241 caaaaacgca aagtagctag attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat gatcaaaaat cacgatatta tctgtattga agacttaaac
      361 acaaaaggta tgttgcgaaa tcataaatta gctaaaagta tttctgatgt ttcttggtca
      421 aagtttgtga ctaaattaca atacaaggct gactggtatg gacgaaaaat catcaaagta
      481 gataaatggt ttccgtctag tcagatttgt tcagagtgcg gacataaaga tggc
//
LOCUS       DAXLPC010000255          531 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.268, whole genome shotgun sequence.
ACCESSION   DAXLPC010000255 DAXLPC010000000
VERSION     DAXLPC010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.268"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>531
                     /locus_tag="ACF3UE_002895"
     rRNA            <1..>531
                     /locus_tag="ACF3UE_002895"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          155 a          107 c          150 g          119 t
ORIGIN      
        1 gtatgtagtc gtagacccga aaccatgtga tctacccatg tccaggttga aggtgcggta
       61 aaacgcactg gaggaccgaa cccacgtacg ttgaaaagtg cggggatgag gtgtgggtag
      121 cggagaaatt ccaaacgaac ttggagatag ctggttctct ccgaaatagc tttagggcta
      181 gcctcggaat tgagaatgat ggaggtagag cactgtttgg actaggggcc catctcgggt
      241 taccgaattc agataaactc cgaatgccat tcattcatat ccgggagtca gactgtgagt
      301 gataagatcc atagtcgaaa gggaaacagc ccagaccacc agctaaggtc ccaaaatata
      361 tgttaagtgg aaaaggatgt ggggttgcac agacaactag gatgttggct tagaagcagc
      421 caccatttaa agagtgcgta atagctcact agtcgagtga ccctgcgccg aaaatgtacc
      481 ggggctaaac atattaccga agctgtggag tacaccttta ggtgtattgg t
//
LOCUS       DAXLPC010000256          505 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.269, whole genome shotgun sequence.
ACCESSION   DAXLPC010000256 DAXLPC010000000
VERSION     DAXLPC010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.269"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..475
                     /locus_tag="ACF3UE_002896"
     CDS             <1..475
                     /locus_tag="ACF3UE_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636198.1"
                     /translation="KKKQQAITPSENKQLEVHQVQEIKTSSNVERQSRGRTKKVGAPI
                     RKFDKVYSTKHPLKLSTLLNATSRVLVEKYETNMTRDELLRKALDEYIKQNLTQEDKQ
                     DLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDTEDSLRKGWGMNNKVR"
BASE COUNT          215 a           73 c           98 g          119 t
ORIGIN      
        1 aaagaaaaag cagcaagcaa ttacaccatc tgaaaataag caattagaag tgcaccaagt
       61 tcaagaaata aaaacttcct ccaatgttga aagacagagt agaggaagaa caaaaaaagt
      121 tggcgcacca atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc
      181 gactttgtta aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag
      241 agatgaattg cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga
      301 taagcaagat ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc
      361 aattgttcca gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca
      421 agataccgaa gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc
      481 aaagaagaac taagtaacta ccttt
//
LOCUS       DAXLPC010000257          503 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.270, whole genome shotgun sequence.
ACCESSION   DAXLPC010000257 DAXLPC010000000
VERSION     DAXLPC010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.270"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            138..431
                     /locus_tag="ACF3UE_002897"
     CDS             138..431
                     /locus_tag="ACF3UE_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFD3636199.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT          201 a           68 c           91 g          143 t
ORIGIN      
        1 agaataaatc tacctataag tagtagtaaa aaaaagagca ctatgataat atctttctta
       61 agagtaaccg ctttaataaa aaatccagaa tattctaaca taaatggagt attcttagaa
      121 tcaaaaggag aaagaagatg gtttatactt atacggagca agaaaagatg aaagttttag
      181 acacattcat gaatgatgga aaagtaaaac aagtaccaag ttcaacaaaa aagaaataca
      241 tcctattgaa agaagtcttg aaacgctttg accatggagt gacttataca gaaacagagg
      301 ttaattcgat actgctgaac gtattttcta gtggcgatta tgtcgaacaa agacgttatc
      361 taatcacatt tggctttttc aaaagaagtt cagacggtcg ggcatatcag atgatgggaa
      421 ttgaaaatta gaagttttaa tttatactca ttgaaaaaag ttcaagtatg cgatattggt
      481 tctacaccgc atacttgaac ttt
//
LOCUS       DAXLPC010000258          499 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.271, whole genome shotgun sequence.
ACCESSION   DAXLPC010000258 DAXLPC010000000
VERSION     DAXLPC010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.271"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>499
                     /locus_tag="ACF3UE_002898"
     rRNA            <1..>499
                     /locus_tag="ACF3UE_002898"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          162 a           99 c          141 g           97 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaa
//
LOCUS       DAXLPC010000259          496 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.272, whole genome shotgun sequence.
ACCESSION   DAXLPC010000259 DAXLPC010000000
VERSION     DAXLPC010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.272"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            125..322
                     /locus_tag="ACF3UE_002899"
     CDS             125..322
                     /locus_tag="ACF3UE_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFD3636200.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            324..>496
                     /locus_tag="ACF3UE_002900"
     CDS             324..>496
                     /locus_tag="ACF3UE_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFD3636201.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYL"
BASE COUNT          188 a           49 c           91 g          168 t
ORIGIN      
        1 cttaaaagtg attaaattct tattcaggaa ttattttgct acgtttcaag aaggaattgt
       61 tttttgaaat ttaatgaatg ttagaataat agtctaaaaa cattaattta ggggtgatta
      121 gattatgaaa catttaaaaa ttttgtctat taaagagaca caacttatct atgggggtac
      181 cactcatagt ggaaaatatt atggaaatgg agtgtattgc actaaaaata aatgtacggt
      241 cgattgggcc aaggcaacta cttgtattgc aggaatgtct ataggtggtt ttttaggtgg
      301 agcaattcca gggaagtgct aaaatgaaaa aaaatgctaa gcaaattgtt catgaattat
      361 ataatgatat atctataagt aaagatccta aatattctga tattcttgag gttttacaaa
      421 aggtatattt aaaattagaa aaacaaaaat atgaattaga tcccggtcct ttaataaata
      481 gattggtgaa ttatct
//
LOCUS       DAXLPC010000260          477 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.273, whole genome shotgun sequence.
ACCESSION   DAXLPC010000260 DAXLPC010000000
VERSION     DAXLPC010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.273"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..248
                     /locus_tag="ACF3UE_002901"
     CDS             <1..248
                     /locus_tag="ACF3UE_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFD3636202.1"
                     /translation="AKEEPFIVDPTVKVVIKKKKIKIYVRGKIRKAFQTGERQTSFIR
                     KVNTNLNALFGAEQTILTEIKFNDYHERNKETKSKVL"
     gene            258..434
                     /locus_tag="ACF3UE_002902"
     CDS             258..434
                     /locus_tag="ACF3UE_002902"
                     /inference="COORDINATES: protein motif:HMM:NF021542.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFD3636203.1"
                     /translation="MKEFIEKYKYPLIFACVGLLLGLLILTLGLFKIVIITILTVCGF
                     YLGIYLETIGFFDK"
BASE COUNT          199 a           56 c           74 g          148 t
ORIGIN      
        1 cagcaaaaga agagcctttt attgttgatc caacggtaaa agttgtaatt aagaagaaaa
       61 aaataaaaat ctatgtacgg ggaaaaatac gtaaagcttt tcaaacaggg gagcgacaaa
      121 cctcctttat aaggaaagta aacactaatt tgaatgcctt atttggtgca gaacaaacaa
      181 tactaactga aataaaattc aatgattatc atgaaagaaa taaagaaacc aaatcaaaag
      241 ttttatagga gaaaacaatg aaagaattca tagagaaata taaatatccg ctcatttttg
      301 catgtgtagg actactatta ggattattaa ttctcacgtt aggacttttt aaaatagtga
      361 taataacaat acttactgta tgtggttttt atttaggtat ctatttagaa actattggat
      421 tttttgacaa ataaaactag ttaataaccg tttttacggt aaaaaataaa tttttat
//
LOCUS       DAXLPC010000261          468 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.274, whole genome shotgun sequence.
ACCESSION   DAXLPC010000261 DAXLPC010000000
VERSION     DAXLPC010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.274"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>468
                     /locus_tag="ACF3UE_002903"
     CDS             <1..>468
                     /locus_tag="ACF3UE_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HFD3636204.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          155 a           86 c           83 g          144 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaa
//
LOCUS       DAXLPC010000262          450 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.275, whole genome shotgun sequence.
ACCESSION   DAXLPC010000262 DAXLPC010000000
VERSION     DAXLPC010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.275"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            15..>450
                     /locus_tag="ACF3UE_002904"
     CDS             15..>450
                     /locus_tag="ACF3UE_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3636205.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAEN"
BASE COUNT          173 a           58 c           92 g          127 t
ORIGIN      
        1 aaggggtgct ttttttgcgg aaatatacat ttgtttttaa gaaaaaagta gtttcagact
       61 atttaaataa cgaaggcggc tacaaatatc ttgcacataa atatcaaata aatcgtacac
      121 tggttagaca ttgggtaagg atttataact atcatggttg ggaaggcttg gttggaggtg
      181 gcaaaagcta cactacaaaa tttaaacttg atgttataga atatatggaa acaaatggtc
      241 tttctatcca agaaactgct aaaaaattta atatcggttc aaatagaact ctaagtaaat
      301 ggatagagca atatgaagaa ggcggtgctt cttcacttga gagccaaaaa aggggcagaa
      361 aaattagtat gaattccaag ctaaacattc ctaaaaaact taaagatgag tctcttgaag
      421 aagaagttat tcgtttaaga gcagagaacg
//
LOCUS       DAXLPC010000263          435 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.276, whole genome shotgun sequence.
ACCESSION   DAXLPC010000263 DAXLPC010000000
VERSION     DAXLPC010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.276"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..>435)
                     /locus_tag="ACF3UE_002905"
     CDS             complement(<1..>435)
                     /locus_tag="ACF3UE_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3636206.1"
                     /translation="LVMDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQI
                     MNRFRTSHSENQKKYRRLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLS
                     YNEELRTAYHFCQLLRYYFVKRGTEGFQETLKTISSTLPQSFK"
BASE COUNT          122 a           77 c           97 g          139 t
ORIGIN      
        1 tttaaacgac tgaggtaacg tagatgaaat tgttttaagg gtttcttgaa agccttccgt
       61 acctcgttta acgaaataat agcgtaataa ttgacaaaaa tgatacgcag ttcgcaattc
      121 ttcgttgtag cttaacagct catcaacgat ttctgtttga ctaattggtc gtttaaacag
      181 tcgatgataa tgccgtttga gtggctccca tgtcgtggaa tctttgagta agagtttcca
      241 atatcgcttg agccgacggt acttcttctg attttcagag tgtgaggttc gaaaacgatt
      301 catgatctgg acacgtaatt gattgaagct gcgattgatg tgttggacaa tatgaaagcg
      361 gtcagttacg atctccgcat ttggaaagac tgttttaagc aactgacaat agctggcatt
      421 catgtccatc actag
//
LOCUS       DAXLPC010000264          428 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.277, whole genome shotgun sequence.
ACCESSION   DAXLPC010000264 DAXLPC010000000
VERSION     DAXLPC010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.277"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            264..>428
                     /locus_tag="ACF3UE_002906"
     CDS             264..>428
                     /locus_tag="ACF3UE_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3636207.1"
                     /translation="MQTFLTKTSFKKVVLLDYLLEKDNWCAMEELRNLLNVTEKSVLH
                     YIEELEDLFKQ"
BASE COUNT          176 a           44 c           64 g          144 t
ORIGIN      
        1 atttcagaaa aaaattaaac tagattataa taattcttca tgtaaaaata aaaacaatta
       61 cagctatgat gtttaagata aaacaattat gaaatcgata tccgtttata tacttatcat
      121 aagctagaag caaataacta gcctatgtat gtaagtgaga ttatatttat taaaaggctt
      181 cttttgttcg atcagttata gtcgaacgag agaagtttat tctttgatta aaataaacaa
      241 aagtaactta ttgaggtgaa atgatgcaaa cttttttaac taaaacatct ttcaaaaaag
      301 tagttttatt agattatttg ttagaaaaag acaattggtg tgcaatggaa gaacttagaa
      361 atttacttaa tgttacggag aagtcagtct tacactatat agaagaacta gaggatttat
      421 ttaagcaa
//
LOCUS       DAXLPC010000265          420 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.278, whole genome shotgun sequence.
ACCESSION   DAXLPC010000265 DAXLPC010000000
VERSION     DAXLPC010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.278"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            134..>420
                     /locus_tag="ACF3UE_002907"
     CDS             134..>420
                     /locus_tag="ACF3UE_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD3636208.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGT"
BASE COUNT          162 a           52 c           67 g          139 t
ORIGIN      
        1 tttcaaatag ttttgtcatc ctaatcttca gcaacagaaa aaaatccaaa ttttaaaatt
       61 taggcttgac taaaatatat tttctgtata ccatataatc gtgataatca ttatcattta
      121 gaaggagaaa gttatgttag aagtgaaaaa gcttaatgtt tgttataacg attttttagc
      181 attgaacgag atttctttaa aaatacaaga aggtgctcta acaggtatta ttggtccaaa
      241 tggtgctgga aaatctacat tacttaaagc aatgttaaat attatccctc atcagggaga
      301 ggtctccatt aataatgaag atatcaataa aaaactggta aagattgcat atgtagagca
      361 aaaagctgat attgatttta cttttccaat aaaagtaaaa gaatgtgtat ctatgggaac
//
LOCUS       DAXLPC010000266          419 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.279, whole genome shotgun sequence.
ACCESSION   DAXLPC010000266 DAXLPC010000000
VERSION     DAXLPC010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.279"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            15..>419
                     /locus_tag="ACF3UE_002908"
     CDS             15..>419
                     /locus_tag="ACF3UE_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFD3636209.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMS"
BASE COUNT          153 a           78 c           69 g          119 t
ORIGIN      
        1 aagaggactt ccctatgaat gattttacta cagaaattgt gcaaactcta gtcactaaag
       61 gcgatttaaa tgaattattc cgttcgcact tagaaaaagc gataaacaca ctcctacgga
      121 ctgaattaac ggctttttta gattacgaaa aatatgatcg cactggtttt aattcaggta
      181 attcgagaaa cggttcttac tttcgatcaa tcaaaaccga atatggtgaa ttaacattgg
      241 aaatacctag agatcgtaat ggtgagttta aacaacaaac tttaccagcc tacaaaagaa
      301 caaacgatac attggaaacc actattatcc atttattcga aaaaggtgtt acgatgtctg
      361 aaattgctga tttgatcgaa aaaatgtacg gtcatcacta tactccacaa accatgtcc
//
LOCUS       DAXLPC010000267          417 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.280, whole genome shotgun sequence.
ACCESSION   DAXLPC010000267 DAXLPC010000000
VERSION     DAXLPC010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.280"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..159
                     /locus_tag="ACF3UE_002909"
     CDS             <1..159
                     /locus_tag="ACF3UE_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFD3636210.1"
                     /translation="SQLLEVNLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQ
                     VLNKEKVA"
     gene            161..>417
                     /locus_tag="ACF3UE_002910"
     CDS             161..>417
                     /locus_tag="ACF3UE_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFD3636211.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEK"
BASE COUNT          155 a           59 c           77 g          126 t
ORIGIN      
        1 tctcaattat tggaagtcaa tttattaaac caattaaagc ttgcaaaacg tgtaaatctt
       61 tttgattatt ctttagaaga attacaagcc gttcatgagt attggcggtc aatgaatcgt
      121 tactcaaaac aagttttgaa taaagagaaa gtggcttaat atggcaaata tagtcaattt
      181 tactgacaaa caatttgaga atcgcttaaa tgataattta gaagaattga ttcaaggaaa
      241 aaaagcggtt gaatcgccaa ccgctttttt acttggtggg caaccagggt cagggaaaac
      301 cagtttgcga tcagcaattt ttgaagaaac acaagggaat gttattgtca ttgataatga
      361 tacctttaaa caacagcacc ctaattttga tgaactagtg aaactttatg aaaaaga
//
LOCUS       DAXLPC010000268          415 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.281, whole genome shotgun sequence.
ACCESSION   DAXLPC010000268 DAXLPC010000000
VERSION     DAXLPC010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.281"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..339)
                     /locus_tag="ACF3UE_002911"
     CDS             complement(<1..339)
                     /locus_tag="ACF3UE_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3636212.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DAXLPC010000269          397 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.282, whole genome shotgun sequence.
ACCESSION   DAXLPC010000269 DAXLPC010000000
VERSION     DAXLPC010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.282"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>397
                     /locus_tag="ACF3UE_002912"
     CDS             <1..>397
                     /locus_tag="ACF3UE_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFD3636213.1"
                     /translation="MKYNIGKYKERDIYINECIEIVDSLTKNISQILSVHSIENLNND
                     EEYLKINDTLEDILKKYEILANQKKITVNNYILDENVYIGKTALKIILSNLISNAVKY
                     TDVNGVINIGIVNDWLYIENSYGNNKISN"
BASE COUNT          181 a           26 c           58 g          132 t
ORIGIN      
        1 acatgaaata caatattgga aaatataaag aaagagatat ttatattaat gaatgtattg
       61 aaatcgttga tagtttaaca aaaaatattt ctcaaatatt atcagttcat tctatagaaa
      121 atttgaataa tgatgaagaa tatttgaaaa taaatgatac attagaagac atattaaaaa
      181 agtatgaaat attagcaaat caaaagaaaa taactgtcaa taattatata ttagacgaga
      241 atgtttatat aggaaaaaca gctttaaaga ttattctatc taatttgatt agtaatgcgg
      301 taaaatatac tgatgtaaat ggggtaatta atattgggat agttaatgat tggttatata
      361 tagagaattc atacggtaac aataaaattt cgaatat
//
LOCUS       DAXLPC010000270          387 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.283, whole genome shotgun sequence.
ACCESSION   DAXLPC010000270 DAXLPC010000000
VERSION     DAXLPC010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.283"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            95..370
                     /locus_tag="ACF3UE_002913"
     CDS             95..370
                     /locus_tag="ACF3UE_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636214.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
BASE COUNT          165 a           57 c           54 g          111 t
ORIGIN      
        1 atttgattta tatatatttc agtatccttc ttgttttcat ataaccaaag gcgctatgat
       61 ttccatatga aaaaaataaa gtcaggtgaa aaaaatgaaa cttgaggata aaaaagtcat
      121 tttgaagaaa atcaaacgac taccagacca aatagatggc tatacgatct gttctttcaa
      181 aaaagacagg agtataaaag cttatacgca aaacacagaa aaaggaataa tctatttcct
      241 acatgaagaa ggttacgata cccaaacctt tatgtttact gaaaaaaaag aatttcataa
      301 acagatgaaa aaactgattg aaaaagaatt tccaagaagt cataaactct atgtgaatca
      361 gcaattttaa cttctaactg ttcttta
//
LOCUS       DAXLPC010000271          385 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.284, whole genome shotgun sequence.
ACCESSION   DAXLPC010000271 DAXLPC010000000
VERSION     DAXLPC010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.284"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..382
                     /locus_tag="ACF3UE_002914"
     CDS             <1..382
                     /locus_tag="ACF3UE_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFD3636215.1"
                     /translation="KRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWL
                     KTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNR
                     NRIHSSIHYLTPQEFEELAKEKMA"
BASE COUNT          154 a           72 c           68 g           91 t
ORIGIN      
        1 aaaacgaatg actgtggatt gtgtcattca aacattgaat aaagcaaaaa tacattatca
       61 cattccagaa ggaatgattc tacacactga cttgggcagc caatacacag caagagaagt
      121 ggaacaatgg cttaaaacca acaaaataag gcattcttat agtagaaaag gaacacctta
      181 tgataatgct ggaatcgaat ctttccatgc ctcattgaaa aaagaagaag tctacacgac
      241 tagctactca gattttgaag aagcaaatcg agcgctattt agctacattg aaggatttta
      301 taaccgaaat cgaatccata gctcgattca ctatctaacc ccacaggaat ttgaagaatt
      361 agcaaaagaa aaaatggctt aaccg
//
LOCUS       DAXLPC010000272          381 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.285, whole genome shotgun sequence.
ACCESSION   DAXLPC010000272 DAXLPC010000000
VERSION     DAXLPC010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.285"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..>381)
                     /locus_tag="ACF3UE_002915"
     rRNA            complement(<1..>381)
                     /locus_tag="ACF3UE_002915"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           85 a          110 c           94 g           92 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc a
//
LOCUS       DAXLPC010000273          369 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.286, whole genome shotgun sequence.
ACCESSION   DAXLPC010000273 DAXLPC010000000
VERSION     DAXLPC010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..369
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.286"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..274
                     /locus_tag="ACF3UE_002916"
     CDS             <1..274
                     /locus_tag="ACF3UE_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HFD3636216.1"
                     /translation="LIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERINE
                     LIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
BASE COUNT          124 a           64 c           77 g          104 t
ORIGIN      
        1 actcatcaag ctggctaata agggtcaaga ttatgaacat ctagcagatg agattgatga
       61 gctgagagac aagcgacagc tccttttagt agaagatgcc tccctcagtg gcgagaacga
      121 gcgaatcaat gagctgattg aatttatccg caagaacaaa ttccgtacct tagagtacga
      181 tgataagctt gtaaggaaga taatccagag cgttacagtc tatgaagaac acttcgtcat
      241 atccttcaaa tctggcatcg aaatggaaat atgaaaacca gaagtaaata gcccatgatt
      301 ctacagtaga gtcgtgggtt ttcttttgct tgctgattat aataatattt taataactat
      361 tgttattat
//
LOCUS       DAXLPC010000274          362 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.287, whole genome shotgun sequence.
ACCESSION   DAXLPC010000274 DAXLPC010000000
VERSION     DAXLPC010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.287"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..>362)
                     /locus_tag="ACF3UE_002917"
     rRNA            complement(<1..>362)
                     /locus_tag="ACF3UE_002917"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           81 a          114 c           68 g           99 t
ORIGIN      
        1 tctcactaga agcttttctc ggcagtgtga catcaggaac ttcggtacta ttatttccct
       61 ccccatcaca gcttgtcctt aagaaaagaa gcatttgact cctcttcaga cttactgctt
      121 ggacagacat ttccgatcgt ctgcattcct tagcctcctg cgtccctcca ttgctcaaac
      181 aaaaacaacg ggtacaggaa tatcaacctg ttatccatcg cctacgcctg tcggcctcgg
      241 cttaggtccc gactaaccct gggcggacga gccttcccca ggaaacctta gtcattcggt
      301 ggacaggatt ctcacctgtc tttcgctact cataccggca ttctcacttc taagcgctcc
      361 ag
//
LOCUS       DAXLPC010000275          349 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.288, whole genome shotgun sequence.
ACCESSION   DAXLPC010000275 DAXLPC010000000
VERSION     DAXLPC010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.288"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(44..>349)
                     /locus_tag="ACF3UE_002918"
     CDS             complement(44..>349)
                     /locus_tag="ACF3UE_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3636217.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT           98 a           86 c           64 g          101 t
ORIGIN      
        1 atcctcggat ctgattttct ccggcagaag cacaatcatt caattacgct gcctctccag
       61 aggtatcaga tccgcgctca ttatcaagga ttcgcttcgc caatctctgt tgtcgaattt
      121 ggatcggtgt ttcatacgcc aacgtgccat gtaagcgtag atagttccac caatgcacat
      181 aatcaaacaa ttctagacgt agctgtgcca gtgtctcaaa ttggtattga tgcacgaatt
      241 ctactttgac agatttatag gttgattcca caacggcatt atcatacgga caacccttcc
      301 tactcaatga acgagtaatt ccaaaaccat tcagaatctc atgaatggt
//
LOCUS       DAXLPC010000276          339 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.289, whole genome shotgun sequence.
ACCESSION   DAXLPC010000276 DAXLPC010000000
VERSION     DAXLPC010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.289"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            42..164
                     /locus_tag="ACF3UE_002919"
     CDS             42..164
                     /locus_tag="ACF3UE_002919"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636218.1"
                     /translation="MHKPFPDPIQKAIDELGIKNKKRFILVIHYMTCKVRKLVG"
     gene            137..268
                     /locus_tag="ACF3UE_002920"
     CDS             137..268
                     /locus_tag="ACF3UE_002920"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636219.1"
                     /translation="MQSAKACGIAFGLAKWGAKNIENFQSVDIIIDSPQEILDLLEK"
BASE COUNT          122 a           45 c           64 g          108 t
ORIGIN      
        1 atctatattt tgatatacaa attacagctt cagatactaa gttgcataaa ccttttccgg
       61 accccataca aaaggcaatt gatgaattgg gcataaaaaa taagaaacga tttatattgg
      121 tgattcatta tatgacatgc aaagtgcgaa agcttgtggg atagcatttg gtttagctaa
      181 atggggagcc aaaaatatag aaaattttca aagtgtagat ataattattg attctcctca
      241 agaaatactt gatttgttag aaaaatagac aaagagcgtg agataaggat agggtctcac
      301 gctctttgtt tttcgccatt taaagattga aatttttgc
//
LOCUS       DAXLPC010000277          323 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.290, whole genome shotgun sequence.
ACCESSION   DAXLPC010000277 DAXLPC010000000
VERSION     DAXLPC010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.290"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..>323)
                     /locus_tag="ACF3UE_002921"
     rRNA            complement(<1..>323)
                     /locus_tag="ACF3UE_002921"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           64 a           96 c           74 g           89 t
ORIGIN      
        1 ataaatccgg acaacgcttg ccacctacgt attaccgcgg ctgctggcac gtagttagcc
       61 gtggctttct ggttagatac cgtcaaggga tgaacagtta ctctcatcct tgttcttctc
      121 taacaacaga gttttacgat ccgaaaacct tcttcactca cgcggcgttg ctcggtcaga
      181 ctttcgtcca ttgccgaaga ttccctactg ctgcctcccg taggagtttg ggccgtgtct
      241 cagtcccaat gtggccgatc accctctcag gtcggctatg catcgtggcc ttggtgagcc
      301 gttacctcac caactagcta atg
//
LOCUS       DAXLPC010000278          305 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.291, whole genome shotgun sequence.
ACCESSION   DAXLPC010000278 DAXLPC010000000
VERSION     DAXLPC010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.291"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACF3UE_002922"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ACF3UE_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HFD3636220.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           95 a           45 c           50 g          115 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgtt
//
LOCUS       DAXLPC010000279          304 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.292, whole genome shotgun sequence.
ACCESSION   DAXLPC010000279 DAXLPC010000000
VERSION     DAXLPC010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.292"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..>304)
                     /locus_tag="ACF3UE_002923"
     CDS             complement(<1..>304)
                     /locus_tag="ACF3UE_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636221.1"
                     /translation="PLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGLPTQQAI
                     ENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLVSQLES"
BASE COUNT           97 a           64 c           40 g          103 t
ORIGIN      
        1 agattccaat tgtgaaacta aattttcttt catatcaaca ggtatctccc aataaccatc
       61 gatacattga aataactcct cgtcatactc ttcaaaaatt ggatagattc ttaaaaaatc
      121 atcaaatgat aagccttggt cctcatagta atctttgact aatccatttt caattgcctg
      181 ttgggtcggt aaacccgttt cagtaataat tcctctctct accatcgaac gataaaaagt
      241 gcatttatct agcgattgct gggtcgtttc aagataatac tttaatcctt cttcaactaa
      301 aggt
//
LOCUS       DAXLPC010000280          288 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.294, whole genome shotgun sequence.
ACCESSION   DAXLPC010000280 DAXLPC010000000
VERSION     DAXLPC010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.294"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..>288)
                     /locus_tag="ACF3UE_002924"
     CDS             complement(<1..>288)
                     /locus_tag="ACF3UE_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFD3636222.1"
                     /translation="MGTYAGMKVFQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGG
                     QFQRVLLARCLAQNADFIFLDEPFVGIDLISERIIMDTLKELKNQGKTVLIV"
BASE COUNT           83 a           63 c           31 g          111 t
ORIGIN      
        1 cacaattagc actgtttttc cctgattttt caattctttt aacgtatcca taattattcg
       61 ttcactaatt aagtctatcc ctacaaatgg ttcatctaaa aatatgaaat ccgcattttg
      121 agcaagacat cttgctaaaa gtacacgttg aaattgtcct ccagataatt ctcctatttg
      181 atgattagaa tattttccca tatcgacctt ttccaaagcc tttgaaactc tttgccattc
      241 tgcattttta attctttgaa aaactttcat tccggcatat gttcccat
//
LOCUS       DAXLPC010000281          259 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.295, whole genome shotgun sequence.
ACCESSION   DAXLPC010000281 DAXLPC010000000
VERSION     DAXLPC010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.295"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
BASE COUNT          104 a           42 c           27 g           86 t
ORIGIN      
        1 ctctactaca ccatatctat tgacaatcaa ccaaataaaa tacagtattt cacgatatag
       61 tgtgataaat aacaaaatag aagcaataaa gcttcttgtg ttaaaacaat tataaaagaa
      121 ctaaataatt agcccttcta tctataaaaa agtcaatagc gtcactagga tttcctaata
      181 acgctattga ttttcttttc ctctgaaatt aaatcagaaa gatttttcaa taatgataac
      241 tgttttgatt aacagcttt
//
LOCUS       DAXLPC010000282          258 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.296, whole genome shotgun sequence.
ACCESSION   DAXLPC010000282 DAXLPC010000000
VERSION     DAXLPC010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.296"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(170..>258)
                     /locus_tag="ACF3UE_002925"
     CDS             complement(170..>258)
                     /locus_tag="ACF3UE_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFD3636223.1"
                     /translation="AKVNDLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT           77 a           52 c           43 g           86 t
ORIGIN      
        1 gggtcccgag cgcttagtgg gaatttgtac cccttatcga tacaaattcc tcgtaggcgc
       61 tagggacctc tttagcttct tggaagctgt cagtagtata tctaataatt tatctccatt
      121 ccctttagta acgtgtaact ttccaaattt aaaaaagcga ctcatagaat tatttcctcc
      181 cgttaaataa tagataacta ttaaaaatag acaatacttg ctcataagta acggtactta
      241 aatcgtttac tttggcgt
//
LOCUS       DAXLPC010000283          257 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.297, whole genome shotgun sequence.
ACCESSION   DAXLPC010000283 DAXLPC010000000
VERSION     DAXLPC010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.297"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>257
                     /locus_tag="ACF3UE_002926"
     CDS             <1..>257
                     /locus_tag="ACF3UE_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3636224.1"
                     /translation="ILELKRTRFLCHDCGRTFSAKTDLVDEHHQLTKELKQAILMELY
                     ENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL"
BASE COUNT           78 a           56 c           57 g           66 t
ORIGIN      
        1 ctattttaga attaaaacgt acccgttttc tctgccatga ttgtggaagg accttttctg
       61 cgaaaacgga cttagttgat gaacatcatc aactaacaaa ggaactgaag caggcgattc
      121 tcatggaact gtacgaaaat caatcacgta aactaatcgc taagaagtac ttcgtctcgg
      181 atgggacggt gacacggatc ttgcgtgaag caacgaagca ttaccagcca cgtatgaact
      241 tccttccgac ggtgttg
//
LOCUS       DAXLPC010000284          257 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.298, whole genome shotgun sequence.
ACCESSION   DAXLPC010000284 DAXLPC010000000
VERSION     DAXLPC010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.298"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            163..>257
                     /gene="rrf"
                     /locus_tag="ACF3UE_002927"
     rRNA            163..>257
                     /gene="rrf"
                     /locus_tag="ACF3UE_002927"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT           89 a           44 c           64 g           60 t
ORIGIN      
        1 taggtcagga gtggaagtac agtgatgtat ggagcggact gatactaatc gatcgaggac
       61 ttaaccaata ggttaaaaga aaagaactcg gaaaaaaact tatgtgactt caaatccagt
      121 tttgagtgaa caaaatttac tcaataaaag ataacaccac agtgtggtgg cgatagcgag
      181 aaggatacac ctgtaaccat gccgaacaca gaagttaagc ttcttagcgc cgattgtagt
      241 gaggggttgc cccttgt
//
LOCUS       DAXLPC010000285          255 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.299, whole genome shotgun sequence.
ACCESSION   DAXLPC010000285 DAXLPC010000000
VERSION     DAXLPC010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.299"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..>255)
                     /locus_tag="ACF3UE_002928"
     CDS             complement(<1..>255)
                     /locus_tag="ACF3UE_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFD3636225.1"
                     /translation="AEPGHYDEKWQNWKLESLPIFPDRYDFEVAKDKGKQFKIVAELL
                     KKANTIIVATDSDREGENIAWSIIHKANAFSKDKTFKRLW"
BASE COUNT           67 a           51 c           38 g           99 t
ORIGIN      
        1 atccatagtc ttttaaatgt tttatctttt gaaaaggcat ttgctttatg gataatcgac
       61 caggcgatat tttcaccttc tctgtcgcta tctgttgcaa caataattgt atttgccttt
      121 ttgagaagtt ctgcaacaat tttaaactgc tttcccttat cttttgcaac ttcaaaatcg
      181 tatcgatcag gaaaaatcgg caaagattca agtttccaat tttgccactt ttcgtcataa
      241 tgacctggtt ctgct
//
LOCUS       DAXLPC010000286          241 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.301, whole genome shotgun sequence.
ACCESSION   DAXLPC010000286 DAXLPC010000000
VERSION     DAXLPC010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.301"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..220)
                     /locus_tag="ACF3UE_002929"
     CDS             complement(<1..220)
                     /locus_tag="ACF3UE_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3636226.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFP"
BASE COUNT           63 a           45 c           46 g           87 t
ORIGIN      
        1 caggaaaaat gatttcggtt ctcccacaac gtcgcttatt ttctttgtat tgttcaaagt
       61 attcaagtgc tgttccacca catttgagaa agttatagac attgtaaatt gtttggcgtc
      121 cacgtttaag ctgcttcgca acgatagcaa ccggagtttc ttgatgaaaa tatgcttcta
      181 tcattacaag ctcgtttggt gtaagatggg tataagtcat ttatgttcac tctccttgta
      241 t
//
LOCUS       DAXLPC010000287          236 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.302, whole genome shotgun sequence.
ACCESSION   DAXLPC010000287 DAXLPC010000000
VERSION     DAXLPC010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.302"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..>236)
                     /locus_tag="ACF3UE_002930"
     CDS             complement(<1..>236)
                     /locus_tag="ACF3UE_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636227.1"
                     /translation="VVEKENTRKPYTEVENGVSYIVPKGKRRQATLDAMKTNYVHELE
                     RFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEP"
BASE COUNT           57 a           57 c           30 g           92 t
ORIGIN      
        1 ggctctttta ccacttttgt taaggtgtta cgcaaatcac ttttccgcgt caataaattt
       61 cgtttctcca taccaatcat tcgatccttt tcataagaaa aacgttctaa ctcatgtaca
      121 taattggtct tcattgcgtc taatgttgct tgtcttctct tacctttcgg tacgatataa
      181 ctcacaccat tttcaacctc cgtgtaaggt ttacgcgtat tttctttttc aacaac
//
LOCUS       DAXLPC010000288          232 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.304, whole genome shotgun sequence.
ACCESSION   DAXLPC010000288 DAXLPC010000000
VERSION     DAXLPC010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.304"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
BASE COUNT           79 a           35 c           45 g           73 t
ORIGIN      
        1 gagaaaaagc atggaatgcg ctgcatcagg tatcgaggct tagaaaaaaa tcaggtgcat
       61 acgatgcttg tttttgccga aatgagtctg aaaaaattgg tcacttagca gtgggagcat
      121 atgtcttcat attttttatt atacaaaaat agacaaaagt atcagtctac actcttagta
      181 aagaggaaac tgatactttt gtctacagta tgatatttct tacatctact tt
//
LOCUS       DAXLPC010000289          229 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.305, whole genome shotgun sequence.
ACCESSION   DAXLPC010000289 DAXLPC010000000
VERSION     DAXLPC010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.305"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..185
                     /locus_tag="ACF3UE_002931"
     CDS             <1..185
                     /locus_tag="ACF3UE_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFD3636228.1"
                     /translation="YTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQ
                     RILDNELGCANASEAV"
BASE COUNT           61 a           51 c           57 g           60 t
ORIGIN      
        1 aatacacatt tgaaacctta caacaattgg atttggagtt atttgactat gtcaattggt
       61 ggaaccacct tcggttgcac ggtacacttg gctacgagac accggttggt taccgtaacc
      121 agagattggc gcagcgaatc cttgataatg agctcggatg tgctaacgct agcgaggcag
      181 tctaacttta actgttagct cctgccgaag atcgtcacat ccgaggagg
//
LOCUS       DAXLPC010000290          225 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.306, whole genome shotgun sequence.
ACCESSION   DAXLPC010000290 DAXLPC010000000
VERSION     DAXLPC010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.306"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(<1..175)
                     /locus_tag="ACF3UE_002932"
     rRNA            complement(<1..175)
                     /locus_tag="ACF3UE_002932"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           50 a           60 c           49 g           66 t
ORIGIN      
        1 cctgtttcca agtgttatcc ccttctgatg ggcaggttac ccacgtgtta ctcacccgtt
       61 cgccactcct ctttttccgg tggagcaagc tccggtggaa aaagaagcgt tcgacttgca
      121 tgtattaggc acgccgccag cgttcgtcct gagccaggat caaactctca taaaaagttc
      181 gaacaatctt gcgattgtta agctcaattt gtttgctagc atatt
//
LOCUS       DAXLPC010000291          222 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.307, whole genome shotgun sequence.
ACCESSION   DAXLPC010000291 DAXLPC010000000
VERSION     DAXLPC010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.307"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>222
                     /locus_tag="ACF3UE_002933"
     CDS             <1..>222
                     /locus_tag="ACF3UE_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFD3636229.1"
                     /translation="GRKALDIETALNQWFSRFPKNFFKSITFDCGKEFSNWKAISNQH
                     DIDIYFADPGTPSQRPLNENSNGILRRNGL"
BASE COUNT           67 a           46 c           40 g           69 t
ORIGIN      
        1 ggccgtaagg cattagatat tgaaactgcc cttaatcaat ggttttctcg cttccctaaa
       61 aacttcttta aatctattac gtttgactgt ggaaaagaat tttctaactg gaaagccatt
      121 agtaaccaac atgatattga tatatatttt gcggaccctg gaacaccttc tcaacgccca
      181 ttaaacgaga attctaacgg gattctgcgt cgtaatggac tg
//
LOCUS       DAXLPC010000292          204 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.309, whole genome shotgun sequence.
ACCESSION   DAXLPC010000292 DAXLPC010000000
VERSION     DAXLPC010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.309"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>204
                     /locus_tag="ACF3UE_002934"
     rRNA            <1..>204
                     /locus_tag="ACF3UE_002934"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           54 a           42 c           71 g           37 t
ORIGIN      
        1 aagcccccgg ctcaaccggg gagggtcatt ggaaactggg agacttgagt gcagaagagg
       61 agagtggaat tccatgtgta gcggtgaaat gcgtagatat atggaggaac accagtggcg
      121 aaggcggctc tctggtctgt aactgacgct gaggctcgaa agcgtgggga gcaaacagga
      181 ttagataccc tggtagtcca cgcc
//
LOCUS       DAXLPC010000293          203 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.denovo.310, whole genome shotgun sequence.
ACCESSION   DAXLPC010000293 DAXLPC010000000
VERSION     DAXLPC010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..203
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.denovo.310"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..>203
                     /locus_tag="ACF3UE_002935"
     CDS             <1..>203
                     /locus_tag="ACF3UE_002935"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636230.1"
                     /translation="FPDGSSTTVKVPVTVKDKVDWVEIKPIPTIEPEQIMPEEVHKGE
                     GVDLTDNILNLPEGSKVEVVTPV"
BASE COUNT           79 a           40 c           46 g           38 t
ORIGIN      
        1 cttcccagat ggatcaagta caacggttaa ggtaccagta acagtcaaag ataaagtaga
       61 ttgggtagaa atcaagccaa ttccaacaat cgaaccagaa caaatcatgc cagaagaagt
      121 tcataaagga gaaggagttg acctaacgga caacattctg aatcttccag aaggaagtaa
      181 agtggaagtc gtcaccccag tgg
//
LOCUS       DAXLPC010000294        11978 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.guided.081, whole genome shotgun sequence.
ACCESSION   DAXLPC010000294 DAXLPC010000000
VERSION     DAXLPC010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11978
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.guided.081"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            104..799
                     /gene="vanR-A"
                     /locus_tag="ACF3UE_002936"
     CDS             104..799
                     /gene="vanR-A"
                     /locus_tag="ACF3UE_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFD3636231.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            777..1931
                     /locus_tag="ACF3UE_002937"
     CDS             777..1931
                     /locus_tag="ACF3UE_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFD3636232.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2146..3114
                     /locus_tag="ACF3UE_002938"
     CDS             2146..3114
                     /locus_tag="ACF3UE_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFD3636233.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3107..4138
                     /gene="vanA"
                     /locus_tag="ACF3UE_002939"
     CDS             3107..4138
                     /gene="vanA"
                     /locus_tag="ACF3UE_002939"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFD3636234.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4144..4752
                     /locus_tag="ACF3UE_002940"
     CDS             4144..4752
                     /locus_tag="ACF3UE_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFD3636235.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            5202..6092
                     /locus_tag="ACF3UE_002941"
     CDS             5202..6092
                     /locus_tag="ACF3UE_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFD3636236.1"
                     /translation="MLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLENSGTSE
                     NTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDSNIYMS
                     KEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEHNSGL
                     SLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIRYVGLPHS
                     AIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEISGN
                     NIDGVIVTVFPGSTHTNSRR"
     gene            6245..6730
                     /gene="vanZ-A"
                     /locus_tag="ACF3UE_002942"
     CDS             6245..6730
                     /gene="vanZ-A"
                     /locus_tag="ACF3UE_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFD3636237.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            7000..7230
                     /locus_tag="ACF3UE_002943"
     CDS             7000..7230
                     /locus_tag="ACF3UE_002943"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636238.1"
                     /translation="MNKVHVYNHNKFVKEINSDTNSIAKEIASQSPFAELKMTDEYDN
                     LILTTKGFFLDDVPNQIWLKNELMPALTNLQI"
     gene            complement(7277..7540)
                     /locus_tag="ACF3UE_002944"
                     /pseudo
     CDS             complement(7277..7540)
                     /locus_tag="ACF3UE_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043131.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(7565..8887)
                     /locus_tag="ACF3UE_002945"
     CDS             complement(7565..8887)
                     /locus_tag="ACF3UE_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFD3636239.1"
                     /translation="MSDLLSLPDIKTIEPPQENETDMMFKVEAVGPPERCPECGFDKL
                     YKHSSRNQLIMDLPIRLKRVGLQLNRRRYKCRECGSTFWERLISVDEKRSMTKRLLKS
                     IQEQSMSKTFVEVAESVGVDEKTIRNVFKDYVALKEREYQFETPKWLGIDEIHIIRRP
                     RLVLTNIERRTIYDIKPNRNKETVIQRLSEISDRTYIEYVTMDMWKPYKDAVNTILPH
                     AKVVVDKFHVVRMANQALDNVRKSLKAHMSQKERRTLMRERFILLKRKHDLNERESFL
                     LDTWLGNLPALKEAYELKEEFYWIWDTPDPDEGRLCYSQWRHRCMSSNSKDAYKDLVR
                     AVDNWHVEIFNYFDKRLTNAYTESINSIIRQVERMGRGYSFDALRAKILFNEKLHKKR
                     KPRFNSSAFNKAMLYDTFNWYEVNDHDITDNFGVDFSTLIKNLEKGDL"
     gene            complement(9129..10769)
                     /gene="merA"
                     /locus_tag="ACF3UE_002946"
     CDS             complement(9129..10769)
                     /gene="merA"
                     /locus_tag="ACF3UE_002946"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016152 - mercury (II) reductase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA];
                     GO_process: GO:0050787 - detoxification of mercury ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="HFD3636240.1"
                     /translation="MNKFKVNIQGMTCTGCEKHVESALEKIGAKNIESNFRRGEAVFE
                     LPDDIEVESAIKAIDEANYQAGEIEEVSSLENVALINEDDYDLLIIGSGAAAFSSAIK
                     AIEYGAKVGMIERGTVGGTCVNIGCVPSKTLLRAGEINHLSKDNPFKGLQTSAGEVDL
                     ASLITQKDKLVSELRNQKYMDLIDEYNFDLIKGEAKFVDASTVEVNGAKLSAKRFLIA
                     TGASPSLPQISGLEKMDYLTSTTLLELKKIPKRLTVIGSGYIGMELGQLFHHLGSEIT
                     LMQRSERLLKEYDPEISESVEKALIEQGINLVKGATFERVEQSGEIKKVYITVNGSKE
                     VIESDQLLVATGRKPNTDSLNLSAAGVETGKNNEILINDFGQTSNEKIYAAGDVTLGP
                     QFVYVAAYEGGIITDNAIGGLNKKIDLSVVPAVTFTNPTVATVGLTEEQAKEKGYDVK
                     TSVLPLDAVPRAIVNRETTGVFKLVADAETLKVLGVHIVSENAGDVIYAASLAVKFGL
                     TIEDLTETLAPYLTMAEGLKLAALTFDKDVSKLSCCAG"
     gene            complement(10794..11186)
                     /gene="merR"
                     /locus_tag="ACF3UE_002947"
     CDS             complement(10794..11186)
                     /gene="merR"
                     /locus_tag="ACF3UE_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="HFD3636241.1"
                     /translation="MIYRISEFADKCGVNKETIRYYERKNLLQEPHRTEAGYRIYSYD
                     DVKRVGFIKRIQELSFSLSEIYKLLGVVDKDEVRCQDMFEFVSKKQKEVQKQIEDLKR
                     IETMLDDLKQRCPDEKQLHSCPIIETLT"
     gene            11456..11689
                     /locus_tag="ACF3UE_002948"
     CDS             11456..11689
                     /locus_tag="ACF3UE_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636242.1"
                     /translation="MRGINNHQKYDFDLYQIEARSPMSTREITLTVDFIEKKVSGDII
                     AFGDWYDLDIESVNEILKQLKKEGQTLRTINFI"
     gene            complement(11712..11969)
                     /locus_tag="ACF3UE_002949"
     CDS             complement(11712..11969)
                     /locus_tag="ACF3UE_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636243.1"
                     /translation="MANNDLNDINKRIEKLKIQKNILRANSEQNINRKRRTKRLIEKG
                     ALLEKYFEIDYLTVEETEEFLKIFSEYIKANKPKKYQKKEK"
BASE COUNT         3753 a         2194 c         2303 g         3728 t
ORIGIN      
        1 taaaatttgg tagtttataa aaagtatgaa ttattcaggt ataaattcgg ccctataatc
       61 tgataaatta ttaagggcaa acttatgtga aagggtgata actatgagcg ataaaatact
      121 tattgtggat gatgaacatg aaattgccga tttggttgaa ttatacttaa aaaacgagaa
      181 ttatacggtt ttcaaatact ataccgccaa agaagcattg gaatgtatag acaagtctga
      241 gattgacctt gccatattgg acatcatgct tcccggcaca agcggcctta ctatctgtca
      301 aaaaataagg gacaagcaca cctatccgat tatcatgctg accgggaaag atacagaggt
      361 agataaaatt acagggttaa caatcggcgc ggatgattat ataacgaagc cctttcgccc
      421 actggagtta attgctcggg taaaggccca gttgcgccga tacaaaaaat tcagtggagt
      481 aaaggagcag aacgaaaatg ttatcgtcca ctccggcctt gtcattaatg ttaacaccca
      541 tgagtgttat ctgaacgaga agcagttatc ccttactccc accgagtttt caatactgcg
      601 aatcctctgt gaaaacaagg ggaatgtggt tagctccgag ctgctatttc atgagatatg
      661 gggcgacgaa tatttcagca agagcaacaa caccatcacc gtgcatatcc ggcatttgcg
      721 cgaaaaaatg aacgacacca ttgataatcc gaaatatata aaaacggtat ggggggttgg
      781 ttataaaatt gaaaaataaa aaaaacgact attccaaact agaacgaaaa ctttacatgt
      841 atatcgttgc aattgttgtg gtagcaattg tattcgtgtt gtatattcgt tcaatgatcc
      901 gagggaaact tggggattgg atcttaagta ttttggaaaa caaatatgac ttaaatcacc
      961 tggacgcgat gaaattatat caatattcca tacggaacaa tatagatatc tttatttatg
     1021 tggcgattgt cattagtatt cttattctat gtcgcgtcat gctttcaaaa ttcgcaaaat
     1081 actttgacga gataaatacc ggcattgatg tacttattca gaacgaagat aaacaaattg
     1141 agctttctgc ggaaatggat gttatggaac aaaagctcaa cacattaaaa cggactctgg
     1201 aaaagcgaga gcaggatgca aagctggccg aacaaagaaa aaatgacgtt gttatgtact
     1261 tggcgcacga tattaaaacg ccccttacat ccattatcgg ttatttgagc ctgcttgacg
     1321 aggctccaga catgccggta gatcaaaagg caaagtatgt gcatatcacg ttggacaaag
     1381 cgtatcgact cgaacagcta atcgacgagt tttttgagat tacacggtat aacctacaaa
     1441 cgataacgct aacaaaaacg cacatagacc tatactatat gctggtgcag atgaccgatg
     1501 aattttatcc tcagctttcc gcacatggaa aacaggcggt tattcacgcc cccgaggatc
     1561 tgaccgtgtc cggcgaccct gataaactcg cgagagtctt taacaacatt ttgaaaaacg
     1621 ccgctgcata cagtgaggat aacagcatca ttgacattac cgcgggcctc tccggggatg
     1681 tggtgtcaat cgaattcaag aacactggaa gcatcccaaa agataagcta gctgccatat
     1741 ttgaaaagtt ctataggctg gacaatgctc gttcttccga tacgggtggc gcgggacttg
     1801 gattggcgat tgcaaaagaa attattgttc agcatggagg gcagatttac gcggaaagca
     1861 atgataacta tacgacgttt agggtagagc ttccagcgat gccagacttg gttgataaaa
     1921 ggaggtccta agagatgtat ataatttttt aggaaaatct caaggttatc tttacttttt
     1981 cttaggaaat taacaattta atattaagaa acggctcgtt cttacacggt agacttaata
     2041 ccgtaagaac gagccgtttt cgttcttcag agaaagattt gacaagatta ccattggcat
     2101 ccccgtttta tttggtgcct ttcacagaaa gggttggtct taattatgaa taacatcggc
     2161 attactgttt atggatgtga gcaggatgag gcagatgcat tccatgctct ttcgcctcgc
     2221 tttggcgtta tggcaacgat aattaacgcc aacgtgtcgg aatccaacgc caaatccgcg
     2281 cctttcaatc aatgtatcag tgtgggacat aaatcagaga tttccgcctc tattcttctt
     2341 gcgctgaaga gagccggtgt gaaatatatt tctacccgaa gcatcggctg caatcatata
     2401 gatacaactg ctgctaagag aatgggcatc actgtcgaca atgtggcgta ctcgccggat
     2461 agcgttgccg attatactat gatgctaatt cttatggcag tacgcaacgt aaaatcgatt
     2521 gtgcgctctg tggaaaaaca tgatttcagg ttggacagcg accgtggcaa ggtactcagc
     2581 gacatgacag ttggtgtggt gggaacgggc cagataggca aagcggttat tgagcggctg
     2641 cgaggatttg gatgtaaagt gttggcttat agtcgcagcc gaagtataga ggtaaactat
     2701 gtaccgtttg atgagttgct gcaaaatagc gatatcgtta cgcttcatgt gccgctcaat
     2761 acggatacgc actatattat cagccacgaa caaatacaga gaatgaagca aggagcattt
     2821 cttatcaata ctgggcgcgg tccacttgta gatacctatg agttggttaa agcattagaa
     2881 aacgggaaac tgggcggtgc cgcattggat gtattggaag gagaggaaga gtttttctac
     2941 tctgattgca cccaaaaacc aattgataat caatttttac ttaaacttca aagaatgcct
     3001 aacgtgataa tcacaccgca tacggcctat tataccgagc aagcgttgcg tgataccgtt
     3061 gaaaaaacca ttaaaaactg tttggatttt gaaaggagac aggagcatga atagaataaa
     3121 agttgcaata ctgtttgggg gttgctcaga ggagcatgac gtatcggtaa aatctgcaat
     3181 agagatagcc gctaacatta ataaagaaaa atacgagccg ttatacattg gaattacgaa
     3241 atctggtgta tggaaaatgt gcgaaaaacc ttgcgcggaa tgggaaaacg acaattgcta
     3301 ttcagctgta ctctcgccgg ataaaaaaat gcacggatta cttgttaaaa agaaccatga
     3361 atatgaaatc aaccatgttg atgtagcatt ttcagctttg catggcaagt caggtgaaga
     3421 tggatccata caaggtctgt ttgaattgtc cggtatccct tttgtaggct gcgatattca
     3481 aagctcagca atttgtatgg acaaatcgtt gacatacatc gttgcgaaaa atgctgggat
     3541 agctactccc gccttttggg ttattaataa agatgatagg ccggtggcag ctacgtttac
     3601 ctatcctgtt tttgttaagc cggcgcgttc aggctcatcc ttcggtgtga aaaaagtcaa
     3661 tagcgcggac gaattggact acgcaattga atcggcaaga caatatgaca gcaaaatctt
     3721 aattgagcag gctgtttcgg gctgtgaggt cggttgtgcg gtattgggaa acagtgccgc
     3781 gttagttgtt ggcgaggtgg accaaatcag gctgcagtac ggaatctttc gtattcatca
     3841 ggaagtcgag ccggaaaaag gctctgaaaa cgcagttata accgttcccg cagacctttc
     3901 agcagaggag cgaggacgga tacaggaaac ggcaaaaaaa atatataaag cgctcggctg
     3961 tagaggtcta gcccgtgtgg atatgttttt acaagataac ggccgcattg tactgaacga
     4021 agtcaatact ctgcccggtt tcacgtcata cagtcgttat ccccgtatga tggccgctgc
     4081 aggtattgca cttcccgaac tgattgaccg cttgatcgta ttagcgttaa aggggtgata
     4141 agcatggaaa taggatttac ttttttagat gaaatagtac acggtgttcg ttgggacgct
     4201 aaatatgcca cttgggataa tttcaccgga aaaccggttg acggttatga agtaaatcgc
     4261 attgtaggga catacgagtt ggctgaatcg cttttgaagg caaaagaact ggctgctacc
     4321 caagggtacg gattgcttct atgggacggt taccgtccta agcgtgctgt aaactgtttt
     4381 atgcaatggg ctgcacagcc ggaaaataac ctgacaaagg aaagttatta tcccaatatt
     4441 gaccgaactg agatgatttc aaaaggatac gtggcttcaa aatcaagcca tagccgcggc
     4501 agtgccattg atcttacgct ttatcgatta gacacgggtg agcttgtacc aatggggagc
     4561 cgatttgatt ttatggatga acgctctcat catgcggcaa atggaatatc atgcaatgaa
     4621 gcgcaaaatc gcagacgttt gcgctccatc atggaaaaca gtgggtttga agcatatagc
     4681 ctcgaatggt ggcactatgt attaagagac gaaccatacc ccaatagcta ttttgatttc
     4741 cccgttaaat aaacttttaa ccgttgcacg gacaaactat ataagctaac tctttcggca
     4801 ggaaacccga cgtatgtaac tggttcttag ggaatttata tatagtagat agtattgaag
     4861 atgtaaggca gagcgatatt gcggtcatta tctgcgtgcg ctgcggcaag atagcctgat
     4921 aataagactg atcgcataga ggggtggtat ttcacaccgc ccattgtcaa caggcagttc
     4981 agcctcgtta aattcagcat gggtatcact tatgaaaatt catctacatt ggtgataata
     5041 gtaaatccag tagggcgaaa taattgactg taatttacgg ggcaaaacgg cacaatctca
     5101 aacgagattg tgccgtttaa ggggaagatt ctagaaatat ttcatacttc caactatata
     5161 gttaaggagg agactgaaaa tgaagaagtt gttttttttt attgttattg ttattcttaa
     5221 tatacttagg ttatgactac gttaatgaag cactgttttc tcaggaaaaa gtcgaatttc
     5281 aaaattatga tcaaaatccc aaagaacatt tagaaaatag tgggacttct gaaaataccc
     5341 aagagaaaac aattacagaa gaacaggttt atcaaggaaa tctgctatta atcaatagta
     5401 aatatcctgt tcgccaagaa agtgtgaagt cagatatcgt gaatttatct aaacatgacg
     5461 aattaataaa tggatacggg ttgcttgata gtaatattta tatgtcaaaa gaaatagcac
     5521 aaaaattttc agagatggtc aatgatgctg taaagggtgg cgttagtcat tttattatta
     5581 atagtggcta tcgagacttt gatgagcaaa gtgtgcttta ccaagaaatg ggggctgagt
     5641 atgccttacc agcaggttat agtgagcata attcaggttt atcactagat gtaggatcaa
     5701 gcttgacgaa aatggaacga gcccctgaag gaaagtggat agaagaaaat gcttggaaat
     5761 acgggttcat tttacgttat ccagaggaca aaacagagtt aacaggaatt caatatgaac
     5821 catggcatat tcgctatgtt ggtttaccac atagtgcgat tatgaaagaa aagaatttcg
     5881 ttctcgagga atatatggat tacctaaaag aagaaaaaac catttctgtt agtgtaaatg
     5941 gggaaaaata tgagatcttt tattatcctg ttactaaaaa taccaccatt catgtgccga
     6001 ctaatcttcg ttatgagata tcaggaaaca atatagacgg tgtaattgtg acagtgtttc
     6061 ccggatcaac acatactaat tcaaggaggt aaggatggcg gaatgaaacc aacgaaatta
     6121 atgaacagca ttattgtact agcacttttg gggtaacgtt agctttttaa tttaaaaccc
     6181 acgttaacta ggacattgct atactaatga tacaacttaa acaaaagaat tagaggaaat
     6241 tatattggga aaaatattat ctagaggatt gctagcttta tatttagtga cactaatctg
     6301 gttagtgtta ttcaaattac aatacaatat tttatcagta tttaattatc atcaaagaag
     6361 tcttaacttg actccattta ctgctactgg gaatttcaga gagatgatag ataatgttat
     6421 aatctttatt ccatttggct tgcttttgaa tgtcaatttt aaagaaatcg gatttttacc
     6481 taagtttgct tttgtactgg ttttaagtct tacttttgaa ataattcaat ttatcttcgc
     6541 tattggagcg acagacataa cagatgtaat tacaaatact gttggaggct ttcttggact
     6601 gaaattatat ggtttaagca ataagcatat gaatcaaaaa aaattagaca gagttattat
     6661 ttttgtaggt atacttttgc tcgtattatt gctcgtttac cgtacccatt taagaataaa
     6721 ttacgtgtaa gatgtctaaa tcaagcaatc tgatctttca tacacataaa gatattgaat
     6781 gaattggatt agatggaaaa cgggatgtgg ggaaactcgc ccgtaggtgt gaagtgaggg
     6841 gaaaaccggt gataaagtaa aaagcttacc taacactata gtaacaaaga aagcccaatt
     6901 atcaatttta gtgctgagga attggtctct ttaataaatt tccttaacgt tgtaaatccg
     6961 cattttcctg acggtacccc ataaaggaga ataaataaaa tgaataaggt acatgtatat
     7021 aatcataata aatttgtaaa agaaattaat agcgacacga atagcattgc taaagaaatt
     7081 gctagtcaat ccccatttgc tgaattaaaa atgacagatg aatacgataa cttaatttta
     7141 acaacaaaag gctttttcct agatgatgta cctaatcaga tatggctaaa aaatgagtta
     7201 atgccagctc ttacaaattt acagatttaa aaaataacct cacctgatca cattagtata
     7261 attaggtgag gttattttat atattgcgtt gaatattatg tttaatccta tatcttctaa
     7321 atgtttcatg attaatacca gttaaatttt gaacctcttt gtctgaatat ccattcttat
     7381 ataattcaaa agcatgctgt aatctagggc tatcctttgt aaataaaggt tttctacctc
     7441 tatatttttt accgtcttta gcaatcttta ttccctgggc ttgtctttct tttatattct
     7501 ttcgttcaga ttctgcttga tatttatata tttcgggtat tcggatttca tggtggaaaa
     7561 gggcttataa atcacccttc tccaaattct taataagtgt ggaaaaatcg acaccaaagt
     7621 tgtctgtaat gtcgtgatca ttcacttcat accaattgaa agtatcgtat aacatagctt
     7681 tattgaaagc acttgaatta aatcgtggct tacgcttttt atggagcttc tcattgaaaa
     7741 ggattttggc tcgtaaggca tcaaacgagt aacctctacc cattcgctct acctgcctaa
     7801 taatactgtt aattgactcc gtataagcgt tagtgagcct tttatcaaag tagttgaata
     7861 tttcgacatg ccagttgtct acggctctca cgaggtcttt atatgcgtct ttagagttac
     7921 tggacataca acggtgtctc cattgactat aacaaagacg accttcatct ggatcaggag
     7981 tatcccatat ccagtaaaac tcttctttga gttcataggc ttcttttaaa gcaggaagat
     8041 tacctaacca agtatctaag aggaatgatt cacgttcatt tagatcgtgt ttacgcttta
     8101 gaaggataaa cctttcacgc ataagggtac gtctttcttt ttggctcata tgggctttca
     8161 aagactttct gacgttatct aaggcttgat tagccattct aactacatga aacttatcta
     8221 cgacaacttt agcgtgtgga aggatagtgt tcactgcgtc tttgtaaggc ttccacatat
     8281 ccattgtgac gtactcaata taagtcctgt cactgatttc tgaaagacgt tggatgactg
     8341 tttccttgtt acggtttggc ttgatgtcat aaatagtcct gcgttcaata ttagtcaata
     8401 caagccgagg tctacggata atatgtatct cgtctatccc aagccactta ggagtttcaa
     8461 actggtattc acgttctttg agtgccacat agtccttaaa aacgttccta atagttttct
     8521 cgtcaacacc aacgctttct gcgacttcta caaaggtctt agacatggat tgctcttgaa
     8581 tggactttaa aagccttttg gtcatactac gcttttcatc tacagatatt aggcgttccc
     8641 agaaggtaga tccgcattca cgacacttgt atcgtctacg gttcaattgt aagcccactc
     8701 gctttaaacg aatgggcaaa tccataatta gttgatttct tgaactgtgt ttgtacaact
     8761 tgtcaaaacc acattcagga caacgttcag gtggtccgac tgcttcaact ttaaacatca
     8821 tatcggtttc attttcttgt ggtggttcta ttgttttaat gtctggtagg gataataagt
     8881 ctgacatatt gttcatcctt tattactctg cggtgttaag gtatcaatta tagatttgat
     8941 gtcgaaatca tcattgttaa attatttttg tgaccacaaa tgcacttaga aaatccctta
     9001 aagcatttat ataatgggtg atcgcaaaat agtgtatgaa atcttttgta gactttgcta
     9061 aactactgca cacctttagt acagtattag ctggttcact tgaataggga gttgtaaaaa
     9121 aagttccctt agcctgcaca acaagataat ttcgaaacat ctttatcgaa cgtaagtgca
     9181 gctaatttta gcccttcagc cattgttaaa tatggtgcta gggtttctgt taaatcttct
     9241 atcgttaagc caaatttaac agctaatgat gctgcataga tgacatctcc tgcattctca
     9301 gatacaatat gaacccctaa tacttttagt gtttctgcat ctgctactag tttaaataca
     9361 ccggttgttt cacggtttac aattgctctt ggaacagcat ctaaaggtaa tacagatgtc
     9421 ttcacatcat accctttctc ttttgcttgt tcttctgtta aaccaaccgt tgcaaccgtc
     9481 ggattcgtaa acgtaacagc aggaactacc gataaatcta tttttttgtt taatccaccg
     9541 atagcattat cagtaataat tccaccttca taggctgcta catatacaaa ttgcggtcct
     9601 aacgtcacat ctcctgctgc ataaatcttt tcattacttg tttgaccaaa atcattgatc
     9661 aggatttcat tattttttcc agtttcaaca cctgctgcac ttaaatttaa agaatccgta
     9721 tttggttttc ttccagtggc aacaagtaac tgatctgatt caatgacttc tttactgcca
     9781 tttactgtta tgtaaacctt ttttatctct ccactttgtt caacacgctc aaaagttgcc
     9841 cctttgacaa ggtttatacc ctgttcaatt aacgcttttt caactgactc tgaaatctca
     9901 ggatcatact cctttaaaag tcgctcactt ctttgcataa gcgttatttc tgaacctaaa
     9961 tgatgaaata gttgtccaag ctccattcca atgtatcctg agccaattac agttaatcgt
    10021 tttggtattt tctttaactc aagaagtgtt gtactagtta aatagtccat tttttcaagt
    10081 cctgaaattt ggggcaacga aggcgatgca cctgttgcaa ttaaaaagcg ttttgcagat
    10141 aactttgccc cattgacctc aaccgtacta gcatcaacga attttgcttc acctttaatt
    10201 aaatcaaaat tatattcatc aattaaatcc atatattttt gattccgaag ttcgctcacc
    10261 aatttatcct tttgcgtgat taaactagct aaatccactt ctccagcgga tgtttgtaaa
    10321 cctttaaacg gattgtcttt tgataaatga ttgatttccc ctgccctaag aagagttttt
    10381 gacggaacac agccaatatt cacacaggtt cccccaaccg ttccacgctc aatcattcca
    10441 acttttgcac cgtattctat agctttaatt gccgaagaaa aggcagcagc accagaacca
    10501 ataataagaa ggtcataatc atcttcatta attaacgcca cgttttctag tgatgatact
    10561 tcttcaattt ctccggcttg gtaatttgct tcatcaatcg cctttattgc actttcaacc
    10621 tcaatatcat cgggcagttc aaatactgct tcaccacgac gaaaattaga ctcaatattt
    10681 ttagcaccta tcttttcaag tgctgattct acgtgttttt cacaacccgt acaagtcatt
    10741 ccttgaatgt ttaccttaaa tttattcata aaaaagcccc tttcgttaat gtctcatgtt
    10801 aatgtttcta ttattggaca cgaatgtaat tgcttttcat ctggacatcg ttgttttaag
    10861 tcgtctaaca tagtttcaat tcgttttaaa tcctctattt gtttttgcac ttccttttgt
    10921 tttttagaaa caaattcgaa catgtcttga caacgaactt catctttatc tacaacacca
    10981 agtaatttat aaatctcgct taaagaaaaa ctaagttcct gtattcgttt aataaaccca
    11041 acacgcttaa cgtcatcata tgaatatatc cgataaccag cttccgttcg gtgaggttct
    11101 tgtaataaat tttttctctc gtaatatcta atcgtttctt tattaactcc acatttatct
    11161 gcaaactcac taatgcgata aatcatctta tttcacccca tgaatattat aaaccgtgta
    11221 ccatagtacg cggtcaagta aattggacta ttttattttt ccccaacgta tcactcgtat
    11281 gtgattgata cttttatata atactattga ttgtcctaac atcccaccag aaaatccgat
    11341 ttaaacacca gttgttttta aactattaag aaagtaattc cactatatat tccgaagacc
    11401 caaaataaat tttgaaggta atattttaaa agttataaaa gcgacagtaa cagaaatgag
    11461 aggaataaat aatcatcaaa aatacgattt tgatttatat caaatagaag cacgttcgcc
    11521 aatgtcaaca agagaaataa ctttaacagt tgattttata gaaaaaaaag tatcaggtga
    11581 tattatcgct tttggtgatt ggtacgattt ggatatagaa tcagtaaatg aaatattaaa
    11641 gcaattaaaa aaggaaggac aaacattaag aacaatcaat tttatttaaa aaagtatcaa
    11701 aaaaaggaaa attatttttc ctttttttga tactttttag gtttattcgc tttaatatat
    11761 tcagaaaaaa tttttaaaaa ttcttccgtt tcttctacag ttaaatagtc aatttcaaaa
    11821 tacttttcta acaaagcacc tttttcaatt agacgttttg ttcttctttt tctgttaata
    11881 ttttgctcgc tattcgctcg caaaatattt ttttgaattt ttagtttttc tattcttttg
    11941 ttgatgtcat ttaaatcatt atttgccata actattta
//
LOCUS       DAXLPC010000295         5832 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.guided.123, whole genome shotgun sequence.
ACCESSION   DAXLPC010000295 DAXLPC010000000
VERSION     DAXLPC010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.guided.123"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            318..782
                     /locus_tag="ACF3UE_002950"
     CDS             318..782
                     /locus_tag="ACF3UE_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFD3636244.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            766..1395
                     /locus_tag="ACF3UE_002951"
     CDS             766..1395
                     /locus_tag="ACF3UE_002951"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFD3636245.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            1749..3227
                     /gene="msr(C)"
                     /locus_tag="ACF3UE_002952"
     CDS             1749..3227
                     /gene="msr(C)"
                     /locus_tag="ACF3UE_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFD3636246.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            3274..3720
                     /locus_tag="ACF3UE_002953"
     CDS             3274..3720
                     /locus_tag="ACF3UE_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFD3636247.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(3919..4434)
                     /locus_tag="ACF3UE_002954"
     CDS             complement(3919..4434)
                     /locus_tag="ACF3UE_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFD3636248.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            4551..5753
                     /locus_tag="ACF3UE_002955"
     CDS             4551..5753
                     /locus_tag="ACF3UE_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFD3636249.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         1808 a          974 c         1232 g         1818 t
ORIGIN      
        1 tttaagcata ctgatccaat ttctaatatt cgacgggatt cttgcaaaag gcgatttcgg
       61 aaatttttgg cggtgtaaaa ttatctactg cagaagagct atcttctata gtttgataag
      121 aatcaataat cttggtttta gcgttgtgct ttctttatca ttttttccgt tcattctaca
      181 aaaaatttct tttctctata cttttctatt gagagcgttt tttttattac acagctgatt
      241 ctttgacttt tttctttttt tattctatta ttgacaagtc aatcgttgac gagtcaatta
      301 ttagaaagga ggaaattatg tctttagaag agattagtca ccttttatat caaatcaaat
      361 tagccgatca aaaaatcgtc cagatctttg aagaaaatat cggtataagt cttactagat
      421 acgagatcat gatgagactg aaagaagaaa atccattgct acaaagcagt ttgcaagaaa
      481 agttgcagat tgatcaagga gcagttactc gtcatctgaa ggtattggaa gcaaatggct
      541 atgtttcgcg tcagagaaat cctcagaaca accgggaagt gtatgtagcg ctaacagaaa
      601 aagcccagaa gaaaatcaag cattgtgaaa tggaccataa agatacaggt tccgtgctat
      661 ccccggcttt cagcgatgta gaaatgaaac aatttctaac acttttagat aaattgaata
      721 cccaactttg caatataaca acagaaacga aagaggttaa taataatgga acaaaaaaat
      781 gatttttcaa caattatgac tggtagaaga tccgttcgcg tatatgatga aacatacaaa
      841 atcccacacg aagaaatgct ggaaatgatc aaagaagcga cgactgcacc ttcttctgtc
      901 aatatgaaac catggcgctt tgtggtcgct gaaagcgagg aagcaaaaga aatcttgcgt
      961 cctttgatcc gtttcaatac gagacaaaat gatacttctt ctgcaatggt catgattttt
     1021 ggcgatatgc aatgttacga atatggcgaa gaaatctaca accaagctta cgaatcaggg
     1081 aagatgccaa aagaagtcag agatcaacaa ttagctgcga tcattcctta ttacaagagt
     1141 ttttcaagag aagaaatgaa cgatgtagtc aaagtcgatt ctagcttagc ggctatgcaa
     1201 ttcatgttag ttgcgcgtga tcatggctat gaaacaaatc caattggtgg attcgaagca
     1261 gatcagttgg cagaggcatt tggtttggat aaagaccgtt atgttccagt tattatttta
     1321 tcaataggaa aagcggtaga agaaggttac gagtctgttc gtttagcacc agaaaagatc
     1381 actatgttcg aataaaaggt tttcagttac tattcagtag ctattgcttt ttttgaatcg
     1441 tgtgtggtaa cctaataaaa aaggaggtcg gaaaaatgac tgcatcgatg aaattacgtt
     1501 tcgaactttt gaataacaac taaataaatt caaaagacat gtataaacaa caatttcatg
     1561 gatggagtat gtccattttt tcgaacgaca gtagaatagg tgaaagctat gacagatttg
     1621 gtgatttagt catagttatt tcgttcagag taggaaaaga tgtgatgcag tttttttgca
     1681 aacagatttt tctgctcttt tttagtatcg ataattgttg ttttacatga aataggagtg
     1741 taaaacatat ggaaaattta gcagtaaata taacaaatct acaagtcagc tttggcaacc
     1801 agctagaact atctattgat tctcttcgtg tctatcagca agatcgtata gggatcatag
     1861 gagaaaatgg tgtcggtaaa tcgactttgc tcaaactaat agccggtgaa ctttttcccg
     1921 atcatgggaa aatccaaaca gagatcacct tcaactacct gcctcaatta acctatctcg
     1981 ctgaagcaaa ggacctaaat ttggaattag ccagtcattt ccagttaaga ctggaagaaa
     2041 cttcagagcg gaaatggagc ggaggggaag aacgaaagat cgagttgata cgtcttcttt
     2101 cttcttatga acaagggatg cttctagacg agccaacaac ccatctagat agaaaaagta
     2161 ttgatcgact gattgaagag cttcgttatt attatggtac gctggttttt gttagtcatg
     2221 atcgctattt tctagatgag ctagcatcga aaatctggga agtaaaagac ggagaaatcc
     2281 gagagttttc ggggaattat agtgcctatc tcactcaaaa ggaattggag aaaaagactc
     2341 agctacgaga agcagagtcg atcatgaaag agaaaaaacg attggaaaaa tcgatccaag
     2401 aaaagaaaaa acaagcggaa aagttggaaa aagtgtccag taaaaagaaa aagcaacaaa
     2461 tcagactgga tcggttgtct tcctctaaac aaaaagacag tgtacaaaaa gccatccaaa
     2521 agaatgcgaa aacattagag agaagactcc aaaaaatagg agaaacaacc aagccgcagc
     2581 agatgaaaca aatccgtttt ccagtaccaa aatctcttga actccacagc cgctatccca
     2641 tcatgggaca aaatgtccaa ttggaaagaa gtgggagaac attactggta aatggtgatt
     2701 ttcagttttc tttaggtaaa aaaatcgcga ttgtcggtga aaatggttca ggtaagacaa
     2761 ccttattaga acatatccgc aaacaaggag aaggaatcct tctctctccg aaagtaagct
     2821 ttcaagtata tcagcaaaag ggttatcaaa tgacatctga agaatccatc attcgttttg
     2881 tcatgagaca aacagagttt tcagaatcgc ttgtccgtag tttgctgaat cacttagggt
     2941 ttgctcagga aactttgacg aaaccgttat gtacattaag tgggggagaa gcgacccgtc
     3001 tgacgattgc tttgcttttt actaagccaa gtaatgtgtt gctgttagat gaaccgacta
     3061 attttattga tatggcaacg atcgaagctt tagagaagct aatgcaaata tatccgggaa
     3121 cgattttgtt tacttctcat gattcttact ttgtcgagcg tacggctgat gaagtttatg
     3181 aaataaaagg gcagaaaata aaaaaagtac ttacgagaaa tttttaaatg tgctacgatg
     3241 attttcgtga caaatttaaa ggagtggtac agattgccta caaataaaaa agaaggaata
     3301 atttttacaa caatgatgtg ttttttgatg gtcttgggga tgagcgcgta taatttatgg
     3361 ctgcatcaag atcttcattt atcaagtttg ttgattggtc tagtgcctgg attcgtggtg
     3421 gctttcattt tggatgtctt catcatcggt gtgctggcga aaaaaattgc ctttaaacta
     3481 ccagtaaatc cagaaagcaa ggtccaaatg atcttaacta tttcatgctt gatggtttta
     3541 ggaatggtga catgtatgtc tttattcggt gtgatcatgg aacaaggaat acctgatcaa
     3601 ttattctctg cttatatgaa tgcttggaaa atgaatgtga ttgccgcttt accgttgcag
     3661 ttgatcatcg ttggcccgct ttcaagaagt gtgctaaaag caattcaaag taatgaatga
     3721 tggaacactg ttatttgaaa aaaggccttg gcatgctttt tgtcatagtc tcttgaatgc
     3781 agttctagaa aaatagtgat ccgaacgata ggttttggcc tgtcgttcgg atcgcttttt
     3841 cttttccaac tgtattgctc ttttattgaa gataatttgc tcttcaatag atatttctag
     3901 aaaggttctg tttatccctt actcaaaaaa ctgctgcatt tgttctctta cttgctgaca
     3961 ccattggagt tcctgctgac aaagcataat tctgcgctgg atcacaacat aacgtccaaa
     4021 ttcttgtttc ttgtctagcg agaggtcatt caattttttt tgattttttt gcatgatttt
     4081 gttcagctgt tgttctctag tgaatagcag tccagtagct gttgttttat cgagcgtcga
     4141 aaaagcatag atttttgcta gaaattcatc tttttgcgta ggagcgggag tttcctcttt
     4201 gatccattcc tctacaagag cacgtccttc atcagtcaag tggtagatct ttttttgaga
     4261 gtgctcgtct ttgtccaaaa cggtcacata accctgctgg tctaacttgg caagcgttgt
     4321 atagatctga ctgtgatggg cttcccaaaa aattgtgatc agctgcttca attcataccc
     4381 agaacgtggt ttggataaaa gcacgcataa taatatatag gctaaagtat tcataaaaat
     4441 cctacctctc gtcttatttt ctttattata tcacagtaaa gtttccacgt tttacatgtg
     4501 catattgaca tgtaaaataa atcatgtatg atgctaatag agagaaaggg atggaaatat
     4561 tggagaatca aatagatata caagaacaaa caaatgaaga aacaaagggg aaaagttcag
     4621 cgctagttgt agcagctacc tgtatgatcg cttttatggg agtgggtcta gtagacccaa
     4681 tcttaaaaac gattgctgca cagttaaacg ctacgccagc tgaaacgacc ctgttattta
     4741 ctagttacat gttagtcact ggtgtggtga tgctatttac aggtttctta tctagtcgga
     4801 tcggtttgaa aaaaacattg atgacaggat tgtttatcat cgttgtattc gctggtcttg
     4861 gcggattatc tgggaatatc ggaatgctga ttgggttacg tgccggctgg ggtgtcggga
     4921 atgctttatt tgtctctact gctttagcaa cgatcgtcag tattttagtt ggtaacacag
     4981 aaaaagcaat catgatgtat gaagcagcac ttggctgcgg aatggctgtt ggccctctag
     5041 tcggtggggt cttgggcagt ggttcatggc gttatccatt ttttggggta gcatttttga
     5101 tgttttgcgg ttttatagcc ctagcggtac ttttacctga aactgagaaa ccaaagagaa
     5161 aagtaggcct ttgggaaggt gtcaaagcgt taagcaatca taaacttcgt tcagttggac
     5221 taatcgcatt gttatataat ttcggattct ttactttact tgcgtatgcg ccatttttat
     5281 tgattggcta ttctgaatta gaagtcggtt ttgtattttt tggctggggt gtgcttctgg
     5341 ctattgcttc gattttcgtt gcaccggctc ttgagcggaa gtttacgact tatcggacaa
     5401 ttttagcagc atttgtctta ttcattattt gtttgctgtt attaggagct ggaacttcta
     5461 tgccagtcct tgtaccgatc agcattgtgt tagcaggatt tttccaagga attatcaata
     5521 cactgttgac gacgattgct atggaaatac caggtctgca acgaaacgtt gcttcgtcca
     5581 gctatagttt tgtccgcttt ttcggtggag ctttagcacc atttattgca ggtgtgattg
     5641 gtgaacatat tggtgaaagc tatgcgtttt attttgcagg tgccattgtt cttatcagtg
     5701 tatgttgtat catttatcac cgtaattatt ttgctacaaa tgaagaagaa taagaaatca
     5761 gaggttgtga aaaagctgtc ctgcatcaag tcataagaac agccaaacaa aaatagcttc
     5821 tcatattttt cg
//
LOCUS       DAXLPC010000296         4929 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.guided.125, whole genome shotgun sequence.
ACCESSION   DAXLPC010000296 DAXLPC010000000
VERSION     DAXLPC010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4929
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.guided.125"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..153
                     /locus_tag="ACF3UE_002956"
     CDS             <1..153
                     /locus_tag="ACF3UE_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFD3636250.1"
                     /translation="LPEFLHTPFKPILSELLEFYDAENWAKRFITNDSTIYEQYEYDL
                     SSVENK"
     gene            complement(303..1244)
                     /locus_tag="ACF3UE_002957"
     CDS             complement(303..1244)
                     /locus_tag="ACF3UE_002957"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFD3636251.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            1370..2491
                     /locus_tag="ACF3UE_002958"
     CDS             1370..2491
                     /locus_tag="ACF3UE_002958"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFD3636252.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            2749..4251
                     /gene="eat(A)"
                     /locus_tag="ACF3UE_002959"
     CDS             2749..4251
                     /gene="eat(A)"
                     /locus_tag="ACF3UE_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFD3636253.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            4318..4845
                     /locus_tag="ACF3UE_002960"
     CDS             4318..4845
                     /locus_tag="ACF3UE_002960"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFD3636254.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
BASE COUNT         1602 a          891 c         1041 g         1395 t
ORIGIN      
        1 ttaccggaat ttctgcatac accatttaag ccaatcctat cagagctatt ggaattttat
       61 gatgcagaaa attgggcaaa acgatttatc actaacgatt ccactattta tgagcaatac
      121 gaatatgacc tctcctctgt tgaaaacaaa taaaaaacct acattttgaa gagattatgt
      181 actgaaacaa acaagcacaa ttcttatggc atcatgagag ttgtgttttc tttttgatct
      241 tttattgggc ttaaaaaaag agaaccagct gctgattcag ctgattctca tcagagagcc
      301 ttttattctg cgccaaggat tccttctttt gcatggacta attgggtcaa aaaggcacaa
      361 tatggtgtag caatatcata tttttgtcct tttcgccaaa tggcaccatt gatgtagtcg
      421 atttcagtca aacgatggtt tttgatcagg tcttggtaca tagatgggta atgcaacccg
      481 atgttgtcag gatcataagt agaagcaata tgttggtaca cttcttcttg atctagtatg
      541 attccttctt ttgctgcgat agaagcaaat tcagatacga ttgttcgaac catgctctct
      601 gccgcttttt gcgcgcctag ttcagcaata ttacaatcca aaatcgtgca taaaccattc
      661 aatgttccat ttacacaagc ttttcgccaa atggaataac gaacgttatg gctatagatc
      721 ggatttaaat ttgcttcttg aaagacttct acaacttttt ttgtaaatgc ttcgccttct
      781 ggttccaagt tctctagttc gatttctcca tcacctaaca atgtgacttt tccgggacca
      841 gctagaccag ctgtccacat cgtgatccca aataagatat ttttctttgg cacatatttt
      901 tccagtacat cttcatgacc taatccattt agtaaacaca aaacataagt attgtcagta
      961 ataatggatt ggatcgaaca aaacatatca tctaattgat tggcttttgt taatgctacg
     1021 atcaagtcca cgtgttcgtt gctttcgatg atttcttctg gtgaatagat tggcagtttt
     1081 gcgaccactt ctttaccgtt aaagtcagca atcaacccat ttgtacgaat ggcttcaatg
     1141 tgagcaggcc aacgatcgat caagaggacc tcatttccgc tttgatgtag catcaatccg
     1201 attcggctgc ccattgctcc ggccccagct attgcgattt tcatgttttt tctctccttt
     1261 attcaatgag ttccctttta gtatatagaa aaatggaaga aaatagcatt gttttgtttg
     1321 aaaaaaatga aaaaaagtgt cttacttaag aagaaagtga gggatacaga tggatatttt
     1381 ggcggcaatt gattcattta aaggaagtgc ttcttcattt gaactaaatc aggcagttct
     1441 aaatggctgg gaagatcgta aaggaagaaa aatcaatgtg ccgattgcag atggcggaga
     1501 aaatactgca gaagcaatct attacgcgct caggggaaca tggcgtacca ttgatgggat
     1561 ggatctctta ttccgtcagc gaaaaatcag ctatttattg acaacttggc aaggaaaaaa
     1621 caccgcagtc atcgaatctg cacaagcatt ggggttagat ctacttgata aaccaacgga
     1681 tcaaactatc cgacttgctt ccagttatgc cttaggagaa cttattaaag atgcactgct
     1741 tcaagaagta gaacaaatta ttgtcacttt aggaggaagc gggtgtagcg atggtggtct
     1801 aggattactc caatccttgg gtgcttcttt agaagggtac acagaaggaa atcctttatt
     1861 atctactaaa aaacttcatt ttgatcgaag aaacgttctt gtttctaaag taaaattgat
     1921 tatcgctgca gatgttacca atccatatac aggtcaacaa ggagctgctt ggcaatttgg
     1981 aagacaaaaa ggaggaatag atacgacgct agctttctta gataaacaag caggaaagat
     2041 tgctcagcaa ataaaagatt tctgggaggt ggatttagat gatattccag gaagtggagc
     2101 agcaggcggt attggtggag cccttttttt gttgggagcg aagatggttt ctggtttcga
     2161 tttagtcagc caaatcactg gattggaaaa aaagatcgaa caagcagatg tcatcattac
     2221 aggagaaggg cggatcgatc agcaaacgat ccacggaaaa gttccatacg gtgtagcagt
     2281 gcttgcaaaa aaatatcgaa aaccaataat cgctatttgc ggaagtagag accaagagct
     2341 agaaggactt tctgattttc tcccaattgt cttaagtatt catttgggtc caataggttt
     2401 agaagaagca atggaacaca ggcaaacatt agaaaaaaca aaaatcttag gacagacact
     2461 tagcagattt ttcaccatcc tcccgaagta gttgacaaaa tcattttctt tatgctatcg
     2521 taatttcaaa tataggacaa agtgagggat ccgtgcattg aaaaattaag tcgattgatg
     2581 aaagctgcat tcagactgta ccttgtggag acaaggaagc agtgtgcaga ttttcgggat
     2641 tggcttggtt ttttcgatgt atgggtcttt ttgtgtgtat ccaacccttg catcctcttt
     2701 agccagttct gaaaatagga ctggtctttt tttacgaggt gatggaaaat gtctaaaatc
     2761 gaaataaaaa atctgacatt cggctacgac agccaaggca cattattatt tgaacaagca
     2821 aatctaaatt ttgacacaca atggaaacta ggacttatcg gacgaaacgg tcgaggaaag
     2881 acaactttac tgaatattct acaaaacaaa ctaccttatc aagggcaagt aatccatcag
     2941 caagaatttg cctatttccc gcaacagaca aaagataaag aacgtttaac ctattacgtg
     3001 ttaaatgata ttacggattt tgagatatgg gaaatcgaaa gagagctcca attgatgcaa
     3061 acagatcctg aaatcttatg gagagaattc agcacactat cggggggaga gaagacaaaa
     3121 gtcctactgg cacttttatt tgtggatgac actcatttcc cgttaatcga tgaaccaacg
     3181 aatcatttgg atatctctgg tagaaaacaa gtagcggctt atttgaaaaa gaaaaaacaa
     3241 ggcttcatcg tggtcagcca tgaccgggga tttatcgatg aagtagtgga ccatgtttta
     3301 gcaatcgaaa aaagtcaact ggaactttat caagggaatt tctctatcta tgaagaacag
     3361 aaaaaacttc gtgatgaatt tgaaatggct caaaatgaaa aattgaaaaa agaagtcagt
     3421 aggctaaaga aaacagcagc tgaaaaagcc gaatggtctc gttcccgaga aggagataaa
     3481 acaaagaaac aagtcggatt catcgatact gaatctagac gagtgaataa aggagcagtg
     3541 ggtgctgatg ctgcacggac gatgaaacga tccaaagcaa tcgtgaatcg gatggagacc
     3601 cagatcagcg agaaagaaaa actattaaaa gatatcgaat atatcgattc tttgacgatg
     3661 aatagccaag cgtctcacca taagcgactt ttaagcgtag aagatcttca attagggtat
     3721 gaaaatctgt tattcgagcc aattcatttt acaatcgagc ctcatcagcg ggtggcgatt
     3781 tcaggtccta acggtgcagg aaagtcatcc attatccatt atcttctggg ggcattcaac
     3841 ggcaaggtta taggagaaaa ataccagcca aaacatctga gcattagtta tgcaagccaa
     3901 aattatgaag acaatcgagg aacgttggcg gaatttgcag agaaaaacca agtagactac
     3961 caagcatttt tgaacaacct ccgaaagctt gggatggaaa gagatgtttt tcataacaag
     4021 atcgagcaga tgagtatggg ccaacggaaa aaagtggaat tggctaaatc tttatcacag
     4081 ccagctgaac tatatacatg ggatgaacca ttgaattatt tggatgtctt caatcaagaa
     4141 caattagaac aactgatctt gaacgtgaaa cctgccatgt tactagtgga acatgatcaa
     4201 accttcctgg ataaagtatc tactgagatt atttctcttg agagaatcta acccttgtaa
     4261 tctcaagaac aacaaggtat ggttaagggg aactttgcca acgaaggaga gaatcacatg
     4321 ctttatgtaa cgagacacgg agaaacaact tggaacgcac aaggattagt ttgcggacgg
     4381 gcagatgtgc cgctgactga aaaaggacag atgcaggcac agaaactagc agaaaaggta
     4441 gtagatttgc ctgttccaat cacgaaaatc atccattccc ctcttcaacg agcaagagat
     4501 acagcacaag cagttgctga tcgtctcagc ttgccgctga ccgttgatga acgattggta
     4561 gaaatggatt ttggggatta tgatggactg ccaagcaaag atgagaactt tcaaaaagca
     4621 cgtttagcgt tcgctgtacg attcccaaat ggggagtcag tcttagatgt gtatgcacgg
     4681 atcgttcctt tattgaaaga atgcatcgaa gacgaagaaa atgtctatct gttagtttgc
     4741 cataatgcct tgataagagt gatcaatgct tattttcatc cgatgcctaa tgaggggttc
     4801 tttacattca tggtagataa tacagaattg gtttcttatg agtaattatg tttttgtgtt
     4861 atttaaataa aatatttcaa ggcactgctt ttgcttagca gtgccttttt taggttatga
     4921 caattcttt
//
LOCUS       DAXLPC010000297         3736 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.guided.141, whole genome shotgun sequence.
ACCESSION   DAXLPC010000297 DAXLPC010000000
VERSION     DAXLPC010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3736
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.guided.141"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..817
                     /locus_tag="ACF3UE_002961"
     CDS             <1..817
                     /locus_tag="ACF3UE_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein"
                     /protein_id="HFD3636255.1"
                     /translation="LFDSRFKTLQQNPTTHEIILSFLGKVQMEVISALLQEKYHVEIE
                     LKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLN
                     QSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVL
                     KKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCI
                     QEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            924..977
                     /locus_tag="ACF3UE_002962"
                     /pseudo
     CDS             924..977
                     /locus_tag="ACF3UE_002962"
                     /inference="COORDINATES: protein motif:HMM:NF019662.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            1011..2387
                     /gene="tet(L)"
                     /locus_tag="ACF3UE_002963"
     CDS             1011..2387
                     /gene="tet(L)"
                     /locus_tag="ACF3UE_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HFD3636256.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            2951..>3736
                     /gene="mobV"
                     /locus_tag="ACF3UE_002964"
     CDS             2951..>3736
                     /gene="mobV"
                     /locus_tag="ACF3UE_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="HFD3636257.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKGFCCKVLNLLSN"
BASE COUNT         1193 a          567 c          766 g         1210 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccct acgacacatg aaattatact
       61 ttctttctta gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca
      121 tgtggagata gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc
      181 agaatatacc attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc
      241 tgtatcaccg cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata
      301 cttaaatcaa tcatttcaaa atgcagttat ggaagggata cgctatggtt gcgaacaagg
      361 attatatggt tggaatgtga cggattgtaa aatctgtttt aagtatggct tatactatag
      421 ccctgttagt accccagcag attttcggat gcttgctcct attgtattgg aacaagtctt
      481 aaaaaaagct ggaacagaat tgttagagcc atatcttagt tttaaaattt atgcgccaca
      541 ggaatatctt tcacgagcat acaacgatgc tcctaaatat tgtgcgaaca tcgtagacac
      601 tcaattgaaa aataatgagg tcattcttag tggagaaatc cctgctcggt gtattcaaga
      661 atatcgtagt gatttaactt tctttacaaa tggacgtagt gtttgtttaa cagagttaaa
      721 agggtaccat gttactaccg gtgaacctgt ttgccagccc cgtcgtccaa atagtcggat
      781 agataaagta cgatatatgt tcaataaaat aacttagtgt attttatgtt gttatataaa
      841 tatggtttct tgttaaataa gatgaaatat tttttaataa agatttgaat taaagtgtaa
      901 aggaggaatt aattatgaag tgaaatgaat gtaacagggt tcaattaaaa gagggaagcg
      961 tatcattaac cctataaact acgtctgccc tcattattgg agggtgaaat gtgaatacat
     1021 cctattcaca atcgaattta cgacacaacc aaattttaat ttggctttgc attttatctt
     1081 tttttagcgt attaaatgaa atggttttga acgtctcatt acctgatatt gcaaatgatt
     1141 ttaataaacc acctgcgagt acaaactggg tgaacacagc ctttatgtta accttttcca
     1201 ttggaacagc tgtatatgga aagctatctg atcaattagg catcaaaagg ttactcctat
     1261 ttggaattat aataaattgt ttcgggtcgg taattgggtt tgttggccat tctttctttt
     1321 ccttacttat tatggctcgt tttattcaag gggctggtgc agctgcattt ccagcactcg
     1381 taatggttgt agttgcgcgc tatattccaa aggaaaatag gggtaaagca tttggtctta
     1441 ttggatcgat agtagccatg ggagaaggag tcggtccagc gattggtgga atgatagccc
     1501 attatattca ttggtcctat cttctactca ttcctatgat aacaattatc actgttccgt
     1561 ttcttatgaa attattaaag aaagaagtaa ggataaaagg tcattttgat atcaaaggaa
     1621 ttatactaat gtctgtaggc attgtatttt ttatgttgtt tacaacatca tatagcattt
     1681 cttttcttat cgttagcgtg ctgtcattcc tgatatttgt aaaacatatc aggaaagtaa
     1741 cagatccttt tgttgatccc ggattaggga aaaatatacc ttttatgatt ggagttcttt
     1801 gtgggggaat tatatttgga acagtagcag ggtttgtctc tatggttcct tatatgatga
     1861 aagatgttca ccagctaagt actgccgaaa tcggaagtgt aattattttc cctggaacaa
     1921 tgagtgtcat tattttcggc tacattggtg ggatacttgt tgatagaaga ggtcctttat
     1981 acgtgttaaa catcggagtt acatttcttt ctgttagctt tttaactgct tcctttcttt
     2041 tagaaacaac atcatggttc atgacaatta taatcgtatt tgttttaggt gggctttcgt
     2101 tcaccaaaac agttatatca acaattgttt caagtagctt gaaacagcag gaagctggtg
     2161 ctggaatgag tttgcttaac tttaccagct ttttatcaga gggaacaggt attgcaattg
     2221 taggtggttt attatccata cccttacttg atcaaaggtt gttacctatg gaagttgatc
     2281 agtcaactta tctgtatagt aatttgttat tacttttttc aggaatcatt gtcattagtt
     2341 ggctggttac cttgaatgta tataaacatt ctcaaaggga tttctaaatc gttaagggat
     2401 caactttggg agagagttca aaattgatcc tttttttata acaggaattc aaatcttttt
     2461 gttccattaa agggcgcgat tgctgaataa aagatacgag agacctctct tgtatctttt
     2521 ttattttgag tggttttgtc cgttacacta gaaaaccgaa agacaataaa aattttattc
     2581 ttgctgagtc tggctttcgg taagctagac aaaacggaca aaataaaaat tggcaagggt
     2641 ttaaaggtgg agattttttg agtgatcttc tcaaaaaata ctacctgtcc cttgctgatt
     2701 tttaaacgag cacgagagca aaacccccct ttgctgaggt ggcagagggc aggttttttt
     2761 gtttcttttt tctcgtaaaa aaaagaaagg tcttaaaggt tttatggttt tggtcggcac
     2821 tgccgacagc ctcgcagagc acacacttta tgaatataaa gtatagtgtg ttatacttta
     2881 cttggaagtg gttgccggaa agagcgaaaa tgcctcacat ttgtgccacc taaaaaggag
     2941 cgatttacat atgagttatg cagtttgtag aatgcaaaaa gtgaaatcag ctggactaaa
     3001 aggcatgcaa tttcataatc aaagagagcg aaaaagtaga acgaatgatg atattgacca
     3061 tgagcgaaca cgtgaaaatt atgatttgaa aaatgataaa aatattgatt acaacgaacg
     3121 tgtcaaagaa attattgaat cacaaaaaac aggtacaaga aaaacgagga aagatgctgt
     3181 tcttgtaaat gagttgctag taacatctga ccgagatttt tttgagcaac tggatccagg
     3241 agaacaaaaa cgattttttg aggaaagtta taaattattt tccgaacgat atggcaagca
     3301 aaatattgct tatgcaacag ttcataatga tgagcaaacc cctcacatgc atttaggtgt
     3361 tgtgcctatg cgtgatggaa aactgcaagg aaaaaatgtg tttaatcgtc aagaactgtt
     3421 atggctacaa gataaattcc ccgagcatat gaaaaaacag ggttttgagt tgaagcgtgg
     3481 tgaacgtggc tctgaccgta aacatattga gacagctaaa tttaaaaaac aaactttgga
     3541 aaaagagatt gattttctag aaaaaaattt agcagttaaa aaagatgaat ggactgctta
     3601 tagcgataaa gttaaatcag atttagaagt accagcgaaa cgacacatga aaagtgttga
     3661 agtgccaacg ggtgaaaagt ccatgtttgg tttgggaaaa gggttctgtt gcaaagtttt
     3721 aaatctacta tcaaat
//
LOCUS       DAXLPC010000298         3719 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.guided.142, whole genome shotgun sequence.
ACCESSION   DAXLPC010000298 DAXLPC010000000
VERSION     DAXLPC010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.guided.142"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(530..655)
                     /locus_tag="ACF3UE_002965"
     CDS             complement(530..655)
                     /locus_tag="ACF3UE_002965"
                     /inference="COORDINATES: protein motif:HMM:NF019687.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636258.1"
                     /translation="MLFPPFKSSKSRKNPSDKYSYHWDFNTKIAVYYTLIATDAL"
     gene            640..2580
                     /gene="tet(S)"
                     /locus_tag="ACF3UE_002966"
     CDS             640..2580
                     /gene="tet(S)"
                     /locus_tag="ACF3UE_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HFD3636259.1"
                     /translation="MEEIKLKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSG
                     TTKTDTMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAIL
                     LISAKDGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIK
                     QTVNLNLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSL
                     YPVYHGSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLY
                     SGTLHLRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGD
                     KKRLPHREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIV
                     LSFLGEVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASI
                     GLSVTPLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKY
                     GLYYSPVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKY
                     CANILNTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAF
                     QPRRPNNRIDKVRHMFNKINLH"
     gene            2668..2835
                     /locus_tag="ACF3UE_002967"
     CDS             2668..2835
                     /locus_tag="ACF3UE_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFD3636260.1"
                     /translation="MCPICGNKTRLKMREDTELKNFPLFCPKCRQEILIEITKFRITV
                     ITEPDAKTQSR"
     gene            complement(3349..3705)
                     /locus_tag="ACF3UE_002968"
     CDS             complement(3349..3705)
                     /locus_tag="ACF3UE_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFD3636261.1"
                     /translation="MWQTTLSNFDFKPLGLAIKEARLSKGLTREQVGSMIQIAPRYLT
                     NIENKGQQPSFHVVYDLVTLLNISLDGFILGEENSHKSSKRLQVEAQLDCLDEDELVT
                     IGKVIQAIYGEKCKFN"
BASE COUNT         1327 a          577 c          618 g         1197 t
ORIGIN      
        1 atttgatagt agatttaaaa ctttgcaaca gaaccctttt aatgatattt tccaagtcaa
       61 acttaatatt aacaattcaa aactattgga accactgcaa aatattttgt taagcagtat
      121 atatttcaaa aattatacgt aatatatttg tagaaaggtt gtggacagtt gtcctattga
      181 cctgaaaagt aatataatag ctggatgaat aaagaatccc ttatgaactt gtaaatcgtt
      241 attaaatcgc tgaattttga tagccattct gaagagttat cttcaactac tacactaact
      301 tccattaatt tctcattaat ttccctttcg ttcaaaaaat atggttggct ttacaagcat
      361 tctatcatat gatagaatta agataacatt caaaaggaga taataaaaat gcggcaaggt
      421 attcttaaat aaactgtcaa ttagatagcg ggaataatta attaagcatc cttatttaaa
      481 ataaggactg gttttttgtg cccagtttaa gaatactttt atcattttat cataaagcat
      541 ctgtggctat cagtgtgtag tatacagcta tttttgtatt aaaatcccag tgataagagt
      601 atttatcact gggatttttt ctgctttttg agcttttgaa tggaggaaat aaaattgaaa
      661 attattaata tcggtatctt agcacatgtt gatgcaggaa aaactacttt gacagaaagc
      721 ttactataca gtagcggagc aattaaagag ttaggaagtg tagatagcgg tacaacgaaa
      781 acggatacta tgtttttgga acgccagaga ggtattacta ttcagaccgc aataacatct
      841 tttcaacggg aaaatgttaa agtaaatatt gtagatactc ctggacacat ggattttttg
      901 gcagatgtat accgttcatt atctgttttg gatggagcta ttttgctaat ctctgcaaaa
      961 gatggagtac agtcacaaac tcgtatacta ttccatgcac ttagaaagat gaacatacct
     1021 ataatatttt ttattaacaa aattgatcaa aatggaataa atttgccaga tgtttatcaa
     1081 gatattaagg acaaactttc tgacgacatc ataattaagc agactgtgaa tctaaatttg
     1141 aaaccttatg taatagatta tactgaacca gaacaatggg agacagtaat tgtgggaaat
     1201 gattatttat tagaaaaata taccattggg aaaacattga atattgcaga acttgaaaag
     1261 gaggaaaacg aaagaattca aagttgctcc ttatatcctg tttatcacgg aagtgcaaag
     1321 aataatattg gaattaaaca acttatagag gtaattacta gcaaattatt ttcacccaca
     1381 caactcaatt cagataaact ttgtggaaat gtttttaaag tagaatattc agatgatggt
     1441 caacggcttg tctatgtacg tctttatagt ggaacgctac atttgcgaga ctcagtcaat
     1501 atatcagaaa aggaaaaaat aaaagttaca gaaatgtata cttcaataaa tggagaatta
     1561 cgccagatag ataaggcaga gcctggtgag attattattt taaaaaatga gcttttaaaa
     1621 ctaaataacg tacttggaga taaaaaaaga ttaccacata gagaaattct tgagaatcct
     1681 cttcctatgt tacaaacaac aattgaacca tgtaaatcag tacaaagaga aaagttacta
     1741 gatgcacttt ttgaaatatc cgatagtgat ccccttctac aatattatgt agatacagta
     1801 actcacgaaa ttgtgctatc ttttttaggt gaggtccaaa tggaggtaac ttgtactctg
     1861 attcaagaaa aatatcatat tgagatagaa acaagaaaac caactgtcat ttatatggaa
     1921 agaccattaa aaaaatctga atttaccatt gatatcgaag tacctccaaa tcctttctgg
     1981 gcttctattg gtttatctgt aacaccactt cctttgggta gtggcattca gtatgagagc
     2041 ctggtttctc taggttattt aaatcaatca tttcaaaatg cagttatgga aggtatacgc
     2101 tatgggtgtg aacaaggatt gtacggttgg aaattaacag actgtaagat ctgttttaag
     2161 tatggtctat attacagccc tgtcagtacg ccagcagatt tccgaatgct tgcgcctatt
     2221 gtactagagc aggcttttag aaagagtggt acagagttat tagagccata tcttagcttc
     2281 gaaatttatg taccacaaga atatctttcg agagcatata atgatgcttc caaatattgt
     2341 gcaaatattt taaatactaa gttaaaaggt aacgaggtca ttctcattgg tgaaattcca
     2401 gcccgttgta ttcaagagta tcgaaacagt ttaactttct ttacaaatgg acgcagtgtc
     2461 tgtttaacag agttaaaagg ttatcaggtt actaacatta agtctgcttt ccaaccacgt
     2521 cgtccaaata atagaataga caaagtaagg catatgttta ataaaatcaa cttacattga
     2581 tagtgaacta aagagaaatt tttaaaatga atattgagtt gttaattaga acaggaggat
     2641 atagatattg taaatactag gtggatactg tgccctatat gtggcaataa gacccgttta
     2701 aaaatgaggg aagatactga attaaaaaat ttccctctat tttgtcctaa atgcagacaa
     2761 gaaattttaa ttgaaataac gaagtttaga ataactgtaa ttacagagcc agacgcaaag
     2821 acgcagagcc gataattcga gatatcaaaa tctcatttta tcggcttttt cttttctatg
     2881 cataccattg agcttagttc ttgatatcct ttataagaaa ataagtgtac tgattttttt
     2941 tgcagtagct gtattacagt agacatccct caagcataaa aagtatacaa ttaaaattca
     3001 atacttgatt attgatgaag tacagagtta ctcgtcattt caaaactagt atatcagtca
     3061 agtttttcct aaggaacaaa aacgaacttc gctatgggaa tcaaaaattt ttagtcggat
     3121 gaagtgatat gcaataaatc cagaaaattt tcccaacaac aaaaaatgaa ctgtactttg
     3181 cagcgataag agtaaccaaa gaactattta tcattcgctc tagttcctaa gtgtaacaaa
     3241 gataaattca ttttctattt atgattaaca aaaatcagaa aaaattcatt acatctttgt
     3301 aatcaatctt tcctgatagt attaattaat ccattgtgta ttattgaact agttaaattt
     3361 acatttttct ccgtaaattg cttgaatcac tttcccaatc gtcactaatt catcttcatc
     3421 cagacaatcc aactgtgctt ctacttgaag acgtttggag cttttatgac tgttttcttc
     3481 ccctaaaata aatccatcca aagaaatatt tagcaaagtc actaaatcat atacaacatg
     3541 aaaacttggc tgttgtcctt tattttcaat gttcgtcaaa tagcgtggcg caatctggat
     3601 cattgatcct acctgctcac gagtcaatcc tttactaaga cgggcttctt taatcgcaag
     3661 acccaatggt ttgaaatcaa aatttgatag agtagtttgc catattcttg cacccaacg
//
LOCUS       DAXLPC010000299         2610 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.guided.163, whole genome shotgun sequence.
ACCESSION   DAXLPC010000299 DAXLPC010000000
VERSION     DAXLPC010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.guided.163"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(530..655)
                     /locus_tag="ACF3UE_002969"
     CDS             complement(530..655)
                     /locus_tag="ACF3UE_002969"
                     /inference="COORDINATES: protein motif:HMM:NF019687.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFD3636262.1"
                     /translation="MLFPPFKSSKSRKNPSDKYSYHWDFNTKIAVYYTLIATDAL"
     gene            640..2592
                     /gene="tet(S)"
                     /locus_tag="ACF3UE_002970"
     CDS             640..2592
                     /gene="tet(S)"
                     /locus_tag="ACF3UE_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011997530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(S)"
                     /protein_id="HFD3636263.1"
                     /translation="MEEIKLKIINIGILAHVDAGKTTLTESLLYSSGAIKELGSVDSG
                     TTKTDTMFLERQRGITIQTAITSFQRENVKVNIVDTPGHMDFLADVYRSLSVLDGAIL
                     LISAKDGVQSQTRILFHALRKMNIPIIFFINKIDQNGINLPDVYQDIKDKLSDDIIIK
                     QTVNLNLKPYVIDYTEPEQWETVIVGNDYLLEKYTIGKTLNIAELEKEENERIQSCSL
                     YPVYHGSAKNNIGIKQLIEVITSKLFSPTQLNSDKLCGNVFKVEYSDDGQRLVYVRLY
                     SGTLHLRDSVNISEKEKIKVTEMYTSINGELRQIDKAEPGEIIILKNELLKLNNVLGD
                     KKRLPHREILENPLPMLQTTIEPCKSVQREKLLDALFEISDSDPLLQYYVDTVTHEIV
                     LSFLGEVQMEVTCTLIQEKYHIEIETRKPTVIYMERPLKKSEFTIDIEVPPNPFWASI
                     GLSVTPLPLGSGIQYESLVSLGYLNQSFQNAVMEGIRYGCEQGLYGWKLTDCKICFKY
                     GLYYSPVSTPADFRMLAPIVLEQAFRKSGTELLEPYLSFEIYVPQEYLSRAYNDASKY
                     CANILNTKLKGNEVILIGEIPARCIQEYRNSLTFFTNGRSVCLTELKGYQVTNIKSAF
                     QPRRPNNRIDKVRHMFNKINGSVAKF"
BASE COUNT          940 a          386 c          453 g          831 t
ORIGIN      
        1 atttgatagt agatttaaaa ctttgcaaca gaaccctttt aatgatattt tccaagtcaa
       61 acttaatatt aacaattcaa aactattgga accactgcaa aatattttgt taagcagtat
      121 atatttcaaa aattatacgt aatatatttg tagaaaggtt gtggacagtt gtcctattga
      181 cctgaaaagt aatataatag ctggatgaat aaagaatccc ttatgaactt gtaaatcgtt
      241 attaaatcgc tgaattttga tagccattct gaagagttat cttcaactac tacactaact
      301 tccattaatt tctcattaat ttccctttcg ttcaaaaaat atggttggct ttacaagcat
      361 tctatcatat gatagaatta agataacatt caaaaggaga taataaaaat gcggcaaggt
      421 attcttaaat aaactgtcaa ttagatagcg ggaataatta attaagcatc cttatttaaa
      481 ataaggactg gttttttgtg cccagtttaa gaatactttt atcattttat cataaagcat
      541 ctgtggctat cagtgtgtag tatacagcta tttttgtatt aaaatcccag tgataagagt
      601 atttatcact gggatttttt ctgctttttg agcttttgaa tggaggaaat aaaattgaaa
      661 attattaata tcggtatctt agcacatgtt gatgcaggaa aaactacttt gacagaaagc
      721 ttactataca gtagcggagc aattaaagag ttaggaagtg tagatagcgg tacaacgaaa
      781 acggatacta tgtttttgga acgccagaga ggtattacta ttcagaccgc aataacatct
      841 tttcaacggg aaaatgttaa agtaaatatt gtagatactc ctggacacat ggattttttg
      901 gcagatgtat accgttcatt atctgttttg gatggagcta ttttgctaat ctctgcaaaa
      961 gatggagtac agtcacaaac tcgtatacta ttccatgcac ttagaaagat gaacatacct
     1021 ataatatttt ttattaacaa aattgatcaa aatggaataa atttgccaga tgtttatcaa
     1081 gatattaagg acaaactttc tgacgacatc ataattaagc agactgtgaa tctaaatttg
     1141 aaaccttatg taatagatta tactgaacca gaacaatggg agacagtaat tgtgggaaat
     1201 gattatttat tagaaaaata taccattggg aaaacattga atattgcaga acttgaaaag
     1261 gaggaaaacg aaagaattca aagttgctcc ttatatcctg tttatcacgg aagtgcaaag
     1321 aataatattg gaattaaaca acttatagag gtaattacta gcaaattatt ttcacccaca
     1381 caactcaatt cagataaact ttgtggaaat gtttttaaag tagaatattc agatgatggt
     1441 caacggcttg tctatgtacg tctttatagt ggaacgctac atttgcgaga ctcagtcaat
     1501 atatcagaaa aggaaaaaat aaaagttaca gaaatgtata cttcaataaa tggagaatta
     1561 cgccagatag ataaggcaga gcctggtgag attattattt taaaaaatga gcttttaaaa
     1621 ctaaataacg tacttggaga taaaaaaaga ttaccacata gagaaattct tgagaatcct
     1681 cttcctatgt tacaaacaac aattgaacca tgtaaatcag tacaaagaga aaagttacta
     1741 gatgcacttt ttgaaatatc cgatagtgat ccccttctac aatattatgt agatacagta
     1801 actcacgaaa ttgtgctatc ttttttaggt gaggtccaaa tggaggtaac ttgtactctg
     1861 attcaagaaa aatatcatat tgagatagaa acaagaaaac caactgtcat ttatatggaa
     1921 agaccattaa aaaaatctga atttaccatt gatatcgaag tacctccaaa tcctttctgg
     1981 gcttctattg gtttatctgt aacaccactt cctttgggta gtggcattca gtatgagagc
     2041 ctggtttctc taggttattt aaatcaatca tttcaaaatg cagttatgga aggtatacgc
     2101 tatgggtgtg aacaaggatt gtacggttgg aaattaacag actgtaagat ctgttttaag
     2161 tatggtctat attacagccc tgtcagtacg ccagcagatt tccgaatgct tgcgcctatt
     2221 gtactagagc aggcttttag aaagagtggt acagagttat tagagccata tcttagcttc
     2281 gaaatttatg taccacaaga atatctttcg agagcatata atgatgcttc caaatattgt
     2341 gcaaatattt taaatactaa gttaaaaggt aacgaggtca ttctcattgg tgaaattcca
     2401 gcccgttgta ttcaagagta tcgaaacagt ttaactttct ttacaaatgg acgcagtgtc
     2461 tgtttaacag agttaaaagg ttatcaggtt actaacatta agtctgcttt ccaaccacgt
     2521 cgtccaaata atagaataga caaagtaagg catatgttta ataaaatcaa cggttctgtt
     2581 gcaaagtttt aaataaagaa taaaatccct
//
LOCUS       DAXLPC010000300         2558 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.guided.166, whole genome shotgun sequence.
ACCESSION   DAXLPC010000300 DAXLPC010000000
VERSION     DAXLPC010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.guided.166"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            <1..173
                     /locus_tag="ACF3UE_002971"
     CDS             <1..173
                     /locus_tag="ACF3UE_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFD3636264.1"
                     /translation="KYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMDIPGMADEMRR
                     PMMLIVSAKKKM"
     gene            206..1114
                     /locus_tag="ACF3UE_002972"
     CDS             206..1114
                     /locus_tag="ACF3UE_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFD3636265.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            1111..1653
                     /gene="sat4"
                     /locus_tag="ACF3UE_002973"
     CDS             1111..1653
                     /gene="sat4"
                     /locus_tag="ACF3UE_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFD3636266.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            1746..2540
                     /locus_tag="ACF3UE_002974"
                     /note="aph(3')-IIIa"
     CDS             1746..2540
                     /locus_tag="ACF3UE_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFD3636267.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          872 a          398 c          603 g          685 t
ORIGIN      
        1 caaaatatca tagaacactg accacatatc taaatacact gctttcaaat agttttataa
       61 taaatcagat tgtggagcca cagccgccag agaacatgat ggatattccg gggatggcgg
      121 atgaaatgcg acgcccaatg atgctgattg tatcggcaaa aaagaagatg taataatata
      181 gaaaaaataa acgaggagta tgtaaatgag atcagaaaaa gaaatgatgg atttagtact
      241 ttctttagca gaacaggatg aacgtattcg aattgtgacc cttgaggggt cacgcgcaaa
      301 tattaatata cctaaagatg aatttcagga ttatgatatt acatattttg taagtgatat
      361 agaaccgttt atatctaatg atgactggct taatcaattt gggaatataa taatgatgca
      421 aaagccggag gatatggaat tattcccacc tgaagaaaag ggattttcct atcttatgct
      481 atttgatgat tacaataaaa ttgatcttac cttattgccc ttggaagagt tagataatta
      541 cctaaagggc gataaattaa taaaggttct aattgataaa gattgtagaa ttaaaaggga
      601 catagttccg actgatatag attatcatgt aagaaagcca agcgcaaggg agtatgatga
      661 ttgctgcaat gaattttgga atgtaacacc ttatgttatt aaaggattgt gccgtaagga
      721 aattttattt gctattgatc attttaatca gattgttcgc catgagctgc tgagaatgat
      781 atcatggaag gtcggcatcg aaacaggctt taaattaagt gtaggcaaga actataagtt
      841 tattgaaagg tatatatccg aggatttgtg ggagaaactt ttgtccacct accggatgga
      901 ttcctatgaa aacatatggg aagcattatt tctatgccat caattgttca gggcggtatc
      961 cggtgaggtg gcggaaaggc ttcattatgc ctatccggag tatgatagga atataacaaa
     1021 atataccagg gacatgtata aaaaatacac tggtaaaacc ggctgcctgg atagcacata
     1081 tgccgctgat atagaagaga ggcgggaaca gtgattacag aaatgaaagc agggcacctg
     1141 aaagatatcg ataaacccag cgaaccattt gaggtgatag gtaagattat accgaggtat
     1201 gaaaacgaga attggacctt tacagaatta ctctatgaag cgccatattt aaaaagctac
     1261 caagacgaag aggatgaaga ggatgaggag gcagattgcc ttgaatatat tgacaatact
     1321 gataagataa tatatcttta ctaccaagac gataaatgcg tcggaaaagt taaactgcga
     1381 aaaaattgga accggtacgc ttatatagaa gatatcgccg tatgtaagga tttcaggggg
     1441 caaggcatag gcagcgcgct tatcaatata tctatagaat gggcaaagca taaaaacttg
     1501 catggactaa tgcttgaaac ccaggacaat aaccttatag cttgtaaatt ctatcataat
     1561 tgtggtttca aaatcggctc cgtcgatact atgttatacg ccaactttga aaacaacttt
     1621 gaaaaagctg ttttctggta tttaaggttt tagaatgcaa ggaacagtga attggagttc
     1681 gtcttgttat aattagcttc ttggggtatc tttaaatact gtagaaaaga ggaaggaaat
     1741 aataaatggc taaaatgaga atatcaccgg aattgaaaaa actgatcgaa aaataccgct
     1801 gcgtaaaaga tacggaagga atgtctcctg ctaaggtata taagctggtg ggagaaaatg
     1861 aaaacctata tttaaaaatg acggacagcc ggtataaagg gaccacctat gatgtggaac
     1921 gggaaaagga catgatgcta tggctggaag gaaagctgcc tgttccaaag gtcctgcact
     1981 ttgaacggca tgatggctgg agcaatctgc tcatgagtga ggccgatggc gtcctttgct
     2041 cggaagagta tgaagatgaa caaagccctg aaaagattat cgagctgtat gcggagtgca
     2101 tcaggctctt tcactccatc gacatatcgg attgtcccta tacgaatagc ttagacagcc
     2161 gcttagccga attggattac ttactgaata acgatctggc cgatgtggat tgcgaaaact
     2221 gggaagaaga cactccattt aaagatccgc gcgagctgta tgatttttta aagacggaaa
     2281 agcccgaaga ggaacttgtc ttttcccacg gcgacctggg agacagcaac atctttgtga
     2341 aagatggcaa agtaagtggc tttattgatc ttgggagaag cggcagggcg gacaagtggt
     2401 atgacattgc cttctgcgtc cggtcgatca gggaggatat cggggaagaa cagtatgtcg
     2461 agctattttt tgacttactg gggatcaagc ctgattggga gaaaataaaa tattatattt
     2521 tactggatga attgttttag tacctagatt tagatgtc
//
LOCUS       DAXLPC010000301         1996 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.guided.184, whole genome shotgun sequence.
ACCESSION   DAXLPC010000301 DAXLPC010000000
VERSION     DAXLPC010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1996
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.guided.184"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            45..437
                     /locus_tag="ACF3UE_002975"
     CDS             45..437
                     /locus_tag="ACF3UE_002975"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFD3636268.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDDIVYVYDYEKGDK"
     gene            438..1877
                     /locus_tag="ACF3UE_002976"
                     /note="aph(2'')-Ia"
     CDS             438..1877
                     /locus_tag="ACF3UE_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFD3636269.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTDKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCSHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          827 a          153 c          344 g          672 t
ORIGIN      
        1 cattgtatag cattttacac aggagtctgg acttgactga gtttatggaa gaagttttaa
       61 ttgatgataa tatggttttt gatattgata atttaaaagg atttcttaat gataccagtt
      121 catttgggtt tatagctaaa gaaaataata aaattatagg atttgcatat tgctatacac
      181 ttttaagacc tgatggaaaa acaatgtttt atttacactc aataggaatg ttacctaact
      241 atcaagacaa aggttatggt tcaaaattat tatcttttat taaggaatat tctaaagaga
      301 ttggttgttc tgaaatgttt ttaataactg ataaaggtaa tcctagagct tgccatgtat
      361 atgaaaaatt aggtggtaaa aatgattata aagatgatat agtatatgta tatgattatg
      421 aaaaaggtga taaataaatg aatatagttg aaaatgaaat atgtataaga actttaatag
      481 atgatgattt tcctttgatg ttaaaatggt taactgatga aagagtatta gaattttatg
      541 atggtagaga taaaaaatat acattagaat cattaaaaaa acattataca gagccttggg
      601 aagatgaagt ttttagagta attattgaat ataacaatgt tcctattgga tatggacaaa
      661 tatataaaat gtatgatgag ttatatactg attatcatta tccaaaaact gatgagatag
      721 tctatggtat ggatcaattt ataggagagc caaattattg gagtaaagga attggtacaa
      781 gatatattaa attgattttt gaatttttga aaaaagaaag aaatgctaat gcagttattt
      841 tagaccctca taaaaataat ccaagagcaa taagggcata ccaaaaatct ggttttagaa
      901 ttattgaaga tttgccagaa catgaattac acgagggcaa aaaagaagat tgttatttaa
      961 tggaatatag atatgatgat aatgccacaa atgttaaggc aatgaaatat ttaattgagc
     1021 attactttga taatttcaaa gtagatagta ttgaaataat cggtagtggt tatgatagtg
     1081 tggcatattt agttaataat gaatacattt ttaaaacaaa atttagtact gataagaaaa
     1141 aaggttatgc aaaagaaaaa gcaatatata attttttaaa tacaaattta gaaactaatg
     1201 taaaaattcc taatattgaa tattcgtata ttagtgatga attatctata ctaggttata
     1261 aagaaattaa aggaactttt ttaacaccag aaatttattc tactatgtca gaagaagaac
     1321 aaaatttgtt aaaacgagat attgccagtt ttttaagaca aatgcacggt ttagattata
     1381 cagatattag tgaatgtact attgataata aacaaaatgt attagaagag tatatattgt
     1441 tgcgtgaaac tatttataat gatttaactg atatagaaaa agattatata gaaagtttta
     1501 tggaaagact aaatgcaaca acagtttttg agggtaaaaa gtgtttatgc cataatgatt
     1561 ttagttgtag tcatctattg ttagatggca ataatagatt aactggaata attgattttg
     1621 gagattctgg aattatagat gaatattgtg attttatata cttacttgaa gatagtgaag
     1681 aagaaatagg aacaaatttt ggagaagata tattaagaat gtatggaaat atagatattg
     1741 agaaagcaaa agaatatcaa gatatagttg aagaatatta tcctattgaa actattgttt
     1801 atggaattaa aaatattaaa caggaattta tcgaaaatgg tagaaaagaa atttataaaa
     1861 ggacttataa agattgatta tataatatat gaaaagctat tataaaagac attagtatta
     1921 aatagtttaa aaaaatgaaa aataataaag gaagtgagtc aagtccagac tcctgtgtaa
     1981 aatgctatac aatgtt
//
LOCUS       DAXLPC010000302         1168 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.guided.220, whole genome shotgun sequence.
ACCESSION   DAXLPC010000302 DAXLPC010000000
VERSION     DAXLPC010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1168
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.guided.220"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            complement(34..336)
                     /locus_tag="ACF3UE_002977"
                     /pseudo
     CDS             complement(34..336)
                     /locus_tag="ACF3UE_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
     gene            429..778
                     /locus_tag="ACF3UE_002978"
                     /pseudo
     CDS             429..778
                     /locus_tag="ACF3UE_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
BASE COUNT          372 a          222 c          159 g          415 t
ORIGIN      
        1 ttttttcatt tacacaaaat attttatact ctcaacatac ttgcaaagta atactacaat
       61 tcctaacata atcgtagaat ttaataattt ccatagcata aagtgtttag aaaagaacat
      121 taagaatagt tctataataa ttcttgaact ccatgtctta taatgttcta tcgaagcacc
      181 caaatagcca agttcatcta atctacttgc ataaactacg tcatccgctc tcatagtcgg
      241 catatacata ttaaagagta aaaagatacc ccaaatccct attagtaaca agatcagttc
      301 tttgttattc gttatttttc tattatgttt gttcattttt atactccttc ttatatttcc
      361 taatagagta taacatagct ttaagcatta cttaaagata acttaaaagt tatcttttaa
      421 atacttaatt gttaaatacc ttatttgatg caaaagaaat ctacgatagt caacaaaaaa
      481 attttcatta tatccagaaa aatttttctt agttaaggac ctatggattg cagtaatgca
      541 gaattcgtcg aataaactgc caaagacata caatcatatt gcttttaaaa ttgacgaaca
      601 agatatagat tcgtttgtct caaaaatcca aatgttaggt ttaactgtcg aaccaggacg
      661 ttctcgtgtg aaaggcgagg cttcttcaat ttacttttac gactatgata atcacctctt
      721 cgagttacat accggtactc tccaggaacg tttaaaatcc tacaattcca ctacctgaga
      781 ctagtaatga ctagtctctt tttatggcct ctgatccccc cattgagcga atactaatag
      841 ggcttcgaat tgatctgttc aatctttaag caatatccct caaatgagtt tggaaagttt
      901 agtgattcat cacaaatact taaatacatg tagttatata tagattgagg ttcttgtgag
      961 cgtatgctcg tgtgggttca aatcccatcg tctgcatcca tctttccaaa acaagcggct
     1021 aggacatttt tgtctcagcc gcttgttttc tagtttattc tttcatcttg tcggaccttt
     1081 tttcttgggt atagactttt ctcatattct accacaattt tgggtttccc taacacatga
     1141 taggatctca caacaaattg ctttctat
//
LOCUS       DAXLPC010000303          798 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.guided.242, whole genome shotgun sequence.
ACCESSION   DAXLPC010000303 DAXLPC010000000
VERSION     DAXLPC010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.guided.242"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            44..781
                     /gene="erm(B)"
                     /locus_tag="ACF3UE_002979"
     CDS             44..781
                     /gene="erm(B)"
                     /locus_tag="ACF3UE_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFD3636270.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          293 a          139 c          125 g          241 t
ORIGIN      
        1 ttctgtattt gtttatagat gtaatcactt caggagtgat aacatgaaca aaaatataaa
       61 atattctcaa aactttttaa cgagtgaaaa agtactcaac caaataataa aacaattgaa
      121 tttaaaagaa accgataccg tttacgaaat tggaacaggt aaagggcatt taacgacgaa
      181 actggctaaa ataagtaaac aggtaacgtc tattgaatta gacagtcatc tattcaactt
      241 atcgtcagaa aaattaaaac tgaatactcg tgtcacttta attcaccaag atattctaca
      301 gtttcaattc cctaacaaac agaggtataa aattgttggg aatattcctt accatttaag
      361 cacacaaatt attaaaaaag tggtttttga aagccgtgcg tctgacatct atctgattgt
      421 tgaagaagga ttctacaagc gtaccttgga tattcaccga acactagggt tgctcttgca
      481 cactcaagtc tcgattcagc aattgcttaa gctgccagcg gaatgctttc atcctaaacc
      541 aaaagtaaac agtgtcttaa taaaacttac ccgccatacc acagatgttc cagataaata
      601 ttggaagcta tatacgtact ttgtttcaaa atgggtcaat cgagaatatc gtcaactgtt
      661 tactaaaaat cagtttcatc aagcaatgaa acacgccaaa gtaaacaatt taagtaccgt
      721 tacttatgag caagtattgt ctatttttaa tagttatcta ttatttaacg ggaggaaata
      781 attctatgag tcgctttt
//
LOCUS       DAXLPC010000304          798 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.guided.243, whole genome shotgun sequence.
ACCESSION   DAXLPC010000304 DAXLPC010000000
VERSION     DAXLPC010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.guided.243"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            44..781
                     /gene="erm(B)"
                     /locus_tag="ACF3UE_002980"
     CDS             44..781
                     /gene="erm(B)"
                     /locus_tag="ACF3UE_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFD3636271.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKYA
                     KVNDLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          292 a          138 c          126 g          242 t
ORIGIN      
        1 ttctgtattt gtttatagat gtaatcactt caggagtgat aacatgaaca aaaatataaa
       61 atattctcaa aactttttaa cgagtgaaaa agtactcaac caaataataa aacaattgaa
      121 tttaaaagaa accgataccg tttacgaaat tggaacaggt aaagggcatt taacgacgaa
      181 actggctaaa ataagtaaac aggtaacgtc tattgaatta gacagtcatc tattcaactt
      241 atcgtcagaa aaattaaaac tgaatactcg tgtcacttta attcaccaag atattctaca
      301 gtttcaattc cctaacaaac agaggtataa aattgttggg aatattcctt accatttaag
      361 cacacaaatt attaaaaaag tggtttttga aagccgtgcg tctgacatct atctgattgt
      421 tgaagaagga ttctacaagc gtaccttgga tattcaccga acactagggt tgctcttgca
      481 cactcaagtc tcgattcagc aattgcttaa gctgccagcg gaatgctttc atcctaaacc
      541 aaaagtaaac agtgtcttaa taaaacttac ccgccatacc acagatgttc cagataaata
      601 ttggaagcta tatacgtact ttgtttcaaa atgggtcaat cgagaatatc gtcaactgtt
      661 tactaaaaat cagtttcatc aagcaatgaa atacgccaaa gtaaacgatt taagtaccgt
      721 tacttatgag caagtattgt ctatttttaa tagttatcta ttatttaacg ggaggaaata
      781 attctatgag tcgctttt
//
LOCUS       DAXLPC010000305          758 bp    DNA     linear   BCT 08-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2587
            SAMD00565645-rid20745033.guided.246, whole genome shotgun sequence.
ACCESSION   DAXLPC010000305 DAXLPC010000000
VERSION     DAXLPC010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565645
            Sequence Read Archive: DRR428031
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054670.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054670.1
            Genome Coverage       :: 73x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 14:40:38
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,981
            CDSs (total)                      :: 2,913
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 1, 4, 4 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 43 of 104
            Pseudo Genes (incomplete)         :: 54 of 104
            Pseudo Genes (internal stop)      :: 28 of 104
            Pseudo Genes (multiple problems)  :: 18 of 104
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565645-rid20745033.guided.246"
                     /strain="JARB-OU2587"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-06-30"
                     /collected_by="Hiroshima"
     gene            145..693
                     /gene="aac(6')"
                     /locus_tag="ACF3UE_002981"
     CDS             145..693
                     /gene="aac(6')"
                     /locus_tag="ACF3UE_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFD3636272.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          275 a          111 c          168 g          204 t
ORIGIN      
        1 gtttctgtat aattttttta ttttataagt aagataaata atgaaagaat agagatactg
       61 attggtagct aaagattttt gagcgagaac atttcgtttt ttcaaaagga ctgttagaat
      121 aagcaagaac aagggggaag acgtatgata atcagtgaat ttgaccgtaa taatccagta
      181 ttgaaagatc agctttctga tttactgaga ctgacttggc cggaagaata tggagacagc
      241 tcggcagaag aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc agcggtagac
      301 caagatgagt tagtaggatt tattggtgca atccctcaat acggtatcac aggttgggaa
      361 ttgcatccat tagttgtaga aagctcccga cgaaagaacc aaataggtac tcgattagtc
      421 aattacttag aaaaagaagt agcttccaga ggaggaatca cgatttattt aggtacggat
      481 gatttagacc atggaacaac gttaagtcaa acggacctgt atgagcatac atttgataaa
      541 gtggcttcca tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa attaggttat
      601 aaaatcgtag gtgtcttacc aaatgcaaat ggctgggaca aaccggatat ttggatggca
      661 aaaacgatta ttcctcgacc aaattctcaa taataaaaag aggttgtgac agaagtaatc
      721 agcttcaaga aataagaagg aatttacgaa aattactt
//
